locus-tag	class	description
GO012_RS00005	COG0716	FMN binding
GO012_RS00010	COG1522	sequence-specific DNA binding
GO012_RS00045	COG1172	Belongs to the binding-protein-dependent transport system permease family
GO012_RS00050	COG1879	ABC-type sugar transport system periplasmic component
GO012_RS00055	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GO012_RS00060	COG1609	Transcriptional regulator
GO012_RS00065	COG0477	Major facilitator Superfamily
GO012_RS00070	COG2186	Transcriptional regulator
GO012_RS00095	COG1763	Mo-molybdopterin cofactor biosynthetic process
GO012_RS00105	COG3084	Protein conserved in bacteria
GO012_RS00110	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
GO012_RS00120	COG0204	Acyl-transferase
GO012_RS00140	COG0635	Involved in the biosynthesis of porphyrin-containing compound
GO012_RS00155	COG3852	Histidine kinase
GO012_RS00160	COG0174	glutamine synthetase
GO012_RS00170	COG1011	Hydrolase
GO012_RS00185	COG0456	acetyltransferase
GO012_RS00195	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
GO012_RS00210	COG2864	formate dehydrogenase
GO012_RS00215	COG0437	4 iron, 4 sulfur cluster binding
GO012_RS00235	COG0205	6-phosphofructokinase activity
GO012_RS00295	COG2211	Major facilitator Superfamily
GO012_RS00305	COG1454	alcohol dehydrogenase
GO012_RS00310	COG1172	Belongs to the binding-protein-dependent transport system permease family
GO012_RS00315	COG1172	Belongs to the binding-protein-dependent transport system permease family
GO012_RS00320	COG1129	ABC transporter
GO012_RS00325	COG1879	ABC-type sugar transport system periplasmic component
GO012_RS00360	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
GO012_RS00365	COG2258	MOSC domain
GO012_RS00370	COG2205	protein histidine kinase activity
GO012_RS00375	COG0745	RESPONSE REGULATOR receiver
GO012_RS00380	COG3678	ATP-independent chaperone mediated protein folding
GO012_RS00400	COG1575	Belongs to the MenA family. Type 1 subfamily
GO012_RS00415	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
GO012_RS00420	COG1609	Transcriptional regulator
GO012_RS00425	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
GO012_RS00440	COG0626	cystathionine gamma-synthase activity
GO012_RS00445	COG0527	aspartate kinase activity
GO012_RS00445	COG0460	homoserine dehydrogenase
GO012_RS00455	COG0737	Belongs to the 5'-nucleotidase family
GO012_RS00465	COG0583	DNA-binding transcription factor activity
GO012_RS00475	COG0697	spore germination
GO012_RS00480	COG0371	Dehydrogenase
GO012_RS00490	COG2207	Transcriptional regulator
GO012_RS00495	COG3443	Belongs to the bacterial solute-binding protein 9 family
GO012_RS00510	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
GO012_RS00525	COG0583	DNA-binding transcription factor activity
GO012_RS00600	COG3085	chromosome segregation
GO012_RS00620	COG3978	acetolactate synthase activity
GO012_RS00625	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
GO012_RS00635	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
GO012_RS00640	COG0583	DNA-binding transcription factor activity
GO012_RS00650	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GO012_RS00655	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GO012_RS00665	COG1811	Na channel or pump
GO012_RS00690	COG3118	belongs to the thioredoxin family
GO012_RS00695	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
GO012_RS00700	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
GO012_RS00710	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
GO012_RS00715	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
GO012_RS00720	COG1088	dTDP-glucose 4,6-dehydratase activity
GO012_RS00725	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
GO012_RS00730	COG0456	acetyltransferase
GO012_RS00735	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
GO012_RS00740	COG2244	polysaccharide biosynthetic process
GO012_RS00760	COG1113	amino acid transport
GO012_RS00785	COG3071	HemY protein
GO012_RS00790	COG2959	enzyme of heme biosynthesis
GO012_RS00805	COG3072	Adenylate cyclase
GO012_RS00815	COG5567	small periplasmic lipoprotein
GO012_RS00835	COG1011	Hydrolase
GO012_RS00840	COG0210	DNA helicase
GO012_RS00845	COG0598	Magnesium transport protein CorA
GO012_RS00855	COG2050	protein possibly involved in aromatic compounds catabolism
GO012_RS00870	COG1280	lysine exporter protein (LysE YggA)
GO012_RS00880	COG1280	lysine exporter protein (LysE YggA)
GO012_RS00885	COG2267	carboxylic ester hydrolase activity
GO012_RS00890	COG0561	phosphatase activity
GO012_RS00900	COG0583	DNA-binding transcription factor activity
GO012_RS00920	COG1322	Protein conserved in bacteria
GO012_RS00930	COG3165	ubiquinone biosynthetic process from chorismate
GO012_RS00940	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
GO012_RS00950	COG0805	protein transport
GO012_RS00990	COG1739	Uncharacterized protein family UPF0029
GO012_RS01000	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
GO012_RS01070	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
GO012_RS01075	COG0250	Participates in transcription elongation, termination and antitermination
GO012_RS01110	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
GO012_RS01115	COG1447	Phosphotransferase system cellobiose-specific component IIA
GO012_RS01125	COG3706	GGDEF domain
GO012_RS01140	COG2104	thiamine diphosphate biosynthetic process
GO012_RS01145	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
GO012_RS01160	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
GO012_RS01180	COG3068	Protein conserved in bacteria
GO012_RS01185	COG0776	regulation of translation
GO012_RS01195	COG3678	ATP-independent chaperone mediated protein folding
GO012_RS01200	COG4191	Histidine kinase
GO012_RS01210	COG0151	Belongs to the GarS family
GO012_RS01240	COG0456	acetyltransferase
GO012_RS01250	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
GO012_RS01300	COG0527	aspartate kinase activity
GO012_RS01310	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
GO012_RS01320	COG0251	oxidation-reduction process
GO012_RS01390	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
GO012_RS01400	COG0534	Mate efflux family protein
GO012_RS01405	COG3237	CsbD-like
GO012_RS01410	COG0735	belongs to the Fur family
GO012_RS01420	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
GO012_RS01435	COG0305	Participates in initiation and elongation during chromosome replication
GO012_RS01440	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
GO012_RS01455	COG0432	Pfam Uncharacterised protein family UPF0047
GO012_RS01460	COG2315	Protein conserved in bacteria
GO012_RS01465	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
GO012_RS01475	COG0741	lytic transglycosylase activity
GO012_RS01480	COG4771	TonB-dependent receptor
GO012_RS01500	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GO012_RS01510	COG0483	inositol monophosphate 1-phosphatase activity
GO012_RS01515	COG1609	Transcriptional regulator
GO012_RS01520	COG1234	tRNA 3'-trailer cleavage
GO012_RS01550	COG4943	cyclic-guanylate-specific phosphodiesterase activity
GO012_RS01560	COG0789	Transcriptional regulator
GO012_RS01565	COG0625	glutathione transferase activity
GO012_RS01570	COG2252	PERMEase
GO012_RS01575	COG0025	NhaP-type Na H and K H
GO012_RS01580	COG0583	DNA-binding transcription factor activity
GO012_RS01585	COG1380	Effector of murein hydrolase LrgA
GO012_RS01590	COG1346	cytolysis
GO012_RS01595	COG3539	Fimbrial protein
GO012_RS01625	COG3162	membrane
GO012_RS01630	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
GO012_RS01640	COG1301	dicarboxylic acid transport
GO012_RS01645	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
GO012_RS01665	COG1879	ABC-type sugar transport system periplasmic component
GO012_RS01670	COG1172	Belongs to the binding-protein-dependent transport system permease family
GO012_RS01675	COG1129	ABC transporter
GO012_RS01680	COG0784	Response regulator, receiver
GO012_RS01680	COG4191	Histidine kinase
GO012_RS01690	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
GO012_RS01700	COG3454	Phosphonate metabolism
GO012_RS01705	COG4778	phosphonate C-P lyase system protein PhnL
GO012_RS01710	COG4107	phosphonate C-P lyase system protein PhnK
GO012_RS01715	COG3627	carbon phosphorus lyase activity
GO012_RS01720	COG3626	phosphonate metabolism
GO012_RS01725	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
GO012_RS01730	COG3624	Phosphonate C-P lyase system protein PhnG
GO012_RS01735	COG2188	Transcriptional regulator
GO012_RS01740	COG2764	glyoxalase bleomycin resistance protein dioxygenase
GO012_RS01745	COG2824	Alkylphosphonate utilization operon protein PhnA
GO012_RS01755	COG2169	Transcriptional regulator
GO012_RS01760	COG1486	melibiose metabolic process
GO012_RS01790	COG0861	Integral membrane protein TerC family
GO012_RS01805	COG1215	transferase activity, transferring glycosyl groups
GO012_RS01810	COG0726	polysaccharide deacetylase
GO012_RS01810	COG1649	PFAM Uncharacterised BCR, COG1649
GO012_RS01815	COG0457	Tetratricopeptide repeat
GO012_RS01850	COG1309	transcriptional regulator
GO012_RS01865	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
GO012_RS01870	COG1027	Aspartate ammonia-lyase
GO012_RS01875	COG3030	protein affecting phage T7 exclusion by the F plasmid
GO012_RS01880	COG0531	amino acid
GO012_RS01930	COG3121	Chaperone
GO012_RS01945	COG1509	lysine 2,3-aminomutase activity
GO012_RS01960	COG5510	response to toxic substance
GO012_RS01965	COG2076	Multidrug Resistance protein
GO012_RS01985	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
GO012_RS01990	COG1053	succinate dehydrogenase
GO012_RS02000	COG0531	amino acid
GO012_RS02005	COG1511	domain protein
GO012_RS02005	COG3264	Mechanosensitive ion channel
GO012_RS02025	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GO012_RS02045	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
GO012_RS02050	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
GO012_RS02050	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
GO012_RS02055	COG0802	atpase or kinase
GO012_RS02060	COG0860	N-Acetylmuramoyl-L-alanine amidase
GO012_RS02080	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
GO012_RS02085	COG0330	HflC and HflK could
GO012_RS02090	COG0330	HflC and HflK could
GO012_RS02100	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
GO012_RS02115	COG0557	exoribonuclease II activity
GO012_RS02120	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GO012_RS02125	COG1960	acyl-CoA dehydrogenase activity
GO012_RS02135	COG3650	response to hydrogen peroxide
GO012_RS02140	COG1073	alpha beta
GO012_RS02160	COG3414	Phosphotransferase system galactitol-specific IIB component
GO012_RS02200	COG2965	DNA replication, synthesis of RNA primer
GO012_RS02215	COG3061	Opacity-associated protein A
GO012_RS02220	COG0545	Peptidyl-prolyl cis-trans isomerase
GO012_RS02225	COG1113	amino acid transport
GO012_RS02235	COG0697	spore germination
GO012_RS02245	COG0702	epimerase
GO012_RS02250	COG1733	regulation of RNA biosynthetic process
GO012_RS02265	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
GO012_RS02280	COG1253	flavin adenine dinucleotide binding
GO012_RS02290	COG0729	surface antigen
GO012_RS02295	COG2911	Protein conserved in bacteria
GO012_RS02300	COG2105	PFAM AIG2 family protein
GO012_RS02310	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
GO012_RS02315	COG1879	ABC-type sugar transport system periplasmic component
GO012_RS02320	COG1129	ABC transporter
GO012_RS02325	COG1172	Belongs to the binding-protein-dependent transport system permease family
GO012_RS02330	COG1172	Belongs to the binding-protein-dependent transport system permease family
GO012_RS02340	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
GO012_RS02360	COG0312	modulator of DNA gyrase
GO012_RS02365	COG3783	Cytochrome b(562)
GO012_RS02395	COG3964	amidohydrolase
GO012_RS02410	COG2706	6-phosphogluconolactonase activity
GO012_RS02415	COG3711	transcriptional antiterminator
GO012_RS02415	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GO012_RS02420	COG3077	Addiction module antitoxin, RelB DinJ family
GO012_RS02425	COG2026	Addiction module toxin, RelE StbE family
GO012_RS02430	COG0602	queuosine metabolic process
GO012_RS02450	COG1486	melibiose metabolic process
GO012_RS02455	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GO012_RS02460	COG0366	Alpha amylase catalytic
GO012_RS02465	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GO012_RS02465	COG1263	PTS System
GO012_RS02505	COG2731	YhcH YjgK YiaL family protein
GO012_RS02515	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
GO012_RS02530	COG0525	valine-tRNA ligase activity
GO012_RS02535	COG2927	DNA polymerase III (CHI subunit)
GO012_RS02545	COG0795	lipopolysaccharide-transporting ATPase activity
GO012_RS02550	COG0795	lipopolysaccharide-transporting ATPase activity
GO012_RS02555	COG0433	COG0433 Predicted ATPase
GO012_RS02570	COG3718	enzyme involved in inositol metabolism
GO012_RS02575	COG1737	Transcriptional regulator
GO012_RS02575	COG0837	glucose binding
GO012_RS02580	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GO012_RS02585	COG3962	Belongs to the TPP enzyme family
GO012_RS02595	COG1082	Xylose isomerase domain protein TIM barrel
GO012_RS02610	COG3842	ATPase activity
GO012_RS02615	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
GO012_RS02620	COG0395	ABC-type sugar transport system, permease component
GO012_RS02630	COG1064	alcohol dehydrogenase
GO012_RS02635	COG0659	secondary active sulfate transmembrane transporter activity
GO012_RS02640	COG0288	reversible hydration of carbon dioxide
GO012_RS02650	COG0582	viral genome integration into host DNA
GO012_RS02735	COG0582	viral genome integration into host DNA
GO012_RS02745	COG3121	Chaperone
GO012_RS02765	COG0673	inositol 2-dehydrogenase activity
GO012_RS02770	COG3732	PTS system glucitol sorbitol-specific
GO012_RS02785	COG3423	Transcriptional regulator
GO012_RS02895	COG0071	Belongs to the small heat shock protein (HSP20) family
GO012_RS03005	COG1216	Glycosyl transferase, family 2
GO012_RS03025	COG3507	Belongs to the glycosyl hydrolase 43 family
GO012_RS03030	COG2211	Major facilitator Superfamily
GO012_RS03035	COG2115	Belongs to the xylose isomerase family
GO012_RS03040	COG4580	involved in the transport of maltose and maltodextrins
GO012_RS03045	COG3272	Protein of unknown function (DUF1722)
GO012_RS03065	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
GO012_RS03080	COG0300	oxidoreductase activity
GO012_RS03085	COG3631	Ketosteroid isomerase-related protein
GO012_RS03090	COG0789	Transcriptional regulator
GO012_RS03095	COG3040	lipid binding
GO012_RS03105	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GO012_RS03110	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GO012_RS03115	COG5569	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GO012_RS03120	COG1538	Outer membrane efflux protein
GO012_RS03125	COG0745	RESPONSE REGULATOR receiver
GO012_RS03130	COG5002	protein histidine kinase activity
GO012_RS03145	COG2850	peptidyl-arginine hydroxylation
GO012_RS03175	COG0842	Transport permease protein
GO012_RS03180	COG1129	ABC transporter
GO012_RS03180	COG0842	Transport permease protein
GO012_RS03185	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GO012_RS03195	COG1879	ABC-type sugar transport system periplasmic component
GO012_RS03200	COG1129	ABC transporter
GO012_RS03205	COG1172	Belongs to the binding-protein-dependent transport system permease family
GO012_RS03215	COG2249	NAD(P)H dehydrogenase (quinone) activity
GO012_RS03220	COG0583	DNA-binding transcription factor activity
GO012_RS03230	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GO012_RS03235	COG5457	Domain of unknown function (DUF1127)
GO012_RS03245	COG1566	PFAM secretion protein HlyD family protein
GO012_RS03260	COG1924	4 iron, 4 sulfur cluster binding
GO012_RS03265	COG1775	2-hydroxyglutaryl-CoA dehydratase, D-component
GO012_RS03275	COG2814	Major facilitator Superfamily
GO012_RS03280	COG2733	membrane
GO012_RS03290	COG2207	Transcriptional regulator
GO012_RS03290	COG1917	Cupin 2, conserved barrel domain protein
GO012_RS03295	COG5464	transposase or invertase
GO012_RS03300	COG1012	belongs to the aldehyde dehydrogenase family
GO012_RS03310	COG0523	cobalamin synthesis protein
GO012_RS03315	COG2879	small protein
GO012_RS03320	COG1966	Carbon starvation protein
GO012_RS03335	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
GO012_RS03340	COG2368	4-hydroxyphenylacetate
GO012_RS03360	COG3971	2-oxopent-4-enoate hydratase activity
GO012_RS03370	COG3384	dioxygenase
GO012_RS03375	COG1012	belongs to the aldehyde dehydrogenase family
GO012_RS03385	COG0179	Fumarylacetoacetate (FAA) hydrolase
GO012_RS03395	COG1846	Transcriptional regulator
GO012_RS03415	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
GO012_RS03430	COG3734	2-keto-3-deoxy-galactonokinase
GO012_RS03435	COG0800	Aldolase
GO012_RS03440	COG1737	Transcriptional regulator
GO012_RS03450	COG1214	PFAM Peptidase M22, glycoprotease
GO012_RS03450	COG0456	acetyltransferase
GO012_RS03455	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
GO012_RS03455	COG3933	PFAM sigma-54 factor interaction domain-containing protein
GO012_RS03470	COG3715	PTS system
GO012_RS03475	COG3716	PTS system mannose fructose sorbose family IID component
GO012_RS03480	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
GO012_RS03490	COG5464	transposase or invertase
GO012_RS03505	COG1484	DNA-dependent DNA replication
GO012_RS03520	COG2966	Psort location CytoplasmicMembrane, score
GO012_RS03535	COG2197	response regulator
GO012_RS03540	COG2197	response regulator
GO012_RS03545	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
GO012_RS03550	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GO012_RS03550	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GO012_RS03555	COG4114	ferric iron reductase
GO012_RS03560	COG3706	GGDEF domain
GO012_RS03590	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
GO012_RS03595	COG0456	acetyltransferase
GO012_RS03600	COG1011	Hydrolase
GO012_RS03610	COG2823	Periplasmic or secreted lipoprotein
GO012_RS03620	COG4667	esterase of the alpha-beta hydrolase superfamily
GO012_RS03625	COG0084	hydrolase, TatD family'
GO012_RS03630	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
GO012_RS03665	COG0560	Phosphoserine phosphatase
GO012_RS03670	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
GO012_RS03680	COG0488	(ABC) transporter
GO012_RS03685	COG0741	lytic transglycosylase activity
GO012_RS03705	COG3708	Transcriptional regulator
GO012_RS03705	COG2207	Transcriptional regulator
GO012_RS03710	COG3045	CreA protein
GO012_RS03715	COG0745	RESPONSE REGULATOR receiver
GO012_RS03720	COG2205	protein histidine kinase activity
GO012_RS03725	COG4452	Inner membrane protein CreD
GO012_RS03730	COG0745	RESPONSE REGULATOR receiver
GO012_RS03740	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
GO012_RS03750	COG0460	homoserine dehydrogenase
GO012_RS03750	COG0527	aspartate kinase activity
GO012_RS03760	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
GO012_RS03775	COG1115	amino acid carrier protein
GO012_RS03785	COG0521	Mo-molybdopterin cofactor biosynthetic process
GO012_RS03790	COG0477	Major facilitator Superfamily
GO012_RS03795	COG1584	GPR1 FUN34 yaaH family protein
GO012_RS03800	COG4735	regulation of single-species biofilm formation
GO012_RS03825	COG0583	DNA-binding transcription factor activity
GO012_RS03840	COG0196	riboflavin kinase activity
GO012_RS03855	COG1047	Peptidyl-prolyl cis-trans
GO012_RS03880	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
GO012_RS03890	COG0505	Belongs to the CarA family
GO012_RS03935	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
GO012_RS03945	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
GO012_RS03950	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
GO012_RS03965	COG3493	citrate carrier protein
GO012_RS03975	COG0564	pseudouridine synthase activity
GO012_RS03985	COG0417	DNA replication proofreading
GO012_RS03990	COG0235	Class ii aldolase
GO012_RS04010	COG0586	Pfam SNARE associated Golgi protein
GO012_RS04020	COG1178	ABC-type Fe3 transport system permease component
GO012_RS04025	COG4143	(ABC) transporter
GO012_RS04040	COG2814	Major facilitator Superfamily
GO012_RS04045	COG2271	Major facilitator Superfamily
GO012_RS04050	COG0583	DNA-binding transcription factor activity
GO012_RS04060	COG0738	Major facilitator superfamily
GO012_RS04105	COG0028	Belongs to the TPP enzyme family
GO012_RS04115	COG1609	Transcriptional regulator
GO012_RS04135	COG0768	penicillin binding
GO012_RS04140	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
GO012_RS04145	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
GO012_RS04160	COG0772	Belongs to the SEDS family
GO012_RS04175	COG1181	Belongs to the D-alanine--D-alanine ligase family
GO012_RS04185	COG0849	cell division
GO012_RS04190	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
GO012_RS04210	COG0494	nUDIX hydrolase
GO012_RS04225	COG0237	dephospho-CoA kinase activity
GO012_RS04235	COG1459	type II secretion system
GO012_RS04240	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
GO012_RS04245	COG4969	Belongs to the N-Me-Phe pilin family
GO012_RS04255	COG3023	N-Acetylmuramoyl-L-alanine amidase
GO012_RS04260	COG3725	Membrane protein required for beta-lactamase induction
GO012_RS04265	COG3940	Belongs to the glycosyl hydrolase 43 family
GO012_RS04270	COG2211	Major facilitator Superfamily
GO012_RS04275	COG1113	amino acid transport
GO012_RS04280	COG2186	Transcriptional regulator
GO012_RS04285	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
GO012_RS04290	COG0508	dehydrogenase complex catalyzes the overall conversion of
GO012_RS04295	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GO012_RS04310	COG3064	Membrane
GO012_RS04355	COG2132	Multicopper oxidase
GO012_RS04360	COG4993	Dehydrogenase
GO012_RS04370	COG0288	reversible hydration of carbon dioxide
GO012_RS04375	COG1131	(ABC) transporter
GO012_RS04380	COG0842	Transport permease protein
GO012_RS04385	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
GO012_RS04390	COG0726	polysaccharide deacetylase
GO012_RS04410	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
GO012_RS04415	COG0617	tRNA 3'-terminal CCA addition
GO012_RS04425	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
GO012_RS04435	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
GO012_RS04440	COG1643	Atp-dependent helicase
GO012_RS04535	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GO012_RS04540	COG4774	siderophore transport
GO012_RS04545	COG1120	ATPase activity
GO012_RS04550	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GO012_RS04555	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GO012_RS04580	COG2860	membrane
GO012_RS04600	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GO012_RS04605	COG3835	regulator
GO012_RS04620	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
GO012_RS04625	COG0024	Methionine aminopeptidase
GO012_RS04650	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
GO012_RS04660	COG0575	Belongs to the CDS family
GO012_RS04665	COG0750	zinc metalloprotease
GO012_RS04675	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
GO012_RS04705	COG0587	DNA-directed DNA polymerase activity
GO012_RS04720	COG0346	lactoylglutathione lyase activity
GO012_RS04730	COG4568	rho-dependent transcription termination
GO012_RS04740	COG4681	YaeQ
GO012_RS04745	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
GO012_RS04750	COG3015	lipoprotein NlpE involved in copper resistance
GO012_RS04755	COG0791	NLP P60 protein
GO012_RS04765	COG1720	tRNA m6t6A37 methyltransferase activity
GO012_RS04775	COG1464	Belongs to the NlpA lipoprotein family
GO012_RS04780	COG2011	ABC-type metal ion transport system permease component
GO012_RS04790	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
GO012_RS04825	COG0656	L-ascorbic acid biosynthetic process
GO012_RS04830	COG0583	DNA-binding transcription factor activity
GO012_RS04835	COG2814	Major facilitator Superfamily
GO012_RS04845	COG2226	methyltransferase
GO012_RS04850	COG0741	lytic transglycosylase activity
GO012_RS04850	COG1388	LysM domain
GO012_RS04860	COG2226	methyltransferase
GO012_RS04870	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
GO012_RS04880	COG0583	DNA-binding transcription factor activity
GO012_RS04890	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
GO012_RS04895	COG1960	acyl-CoA dehydrogenase activity
GO012_RS04905	COG0121	glutamine amidotransferase
GO012_RS04910	COG3034	peptidoglycan biosynthetic process
GO012_RS04925	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
GO012_RS04930	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
GO012_RS04945	COG2991	Protein conserved in bacteria
GO012_RS04960	COG0454	-acetyltransferase
GO012_RS04965	COG2195	Cleaves the N-terminal amino acid of tripeptides
GO012_RS04985	COG1802	Transcriptional regulator
GO012_RS04990	COG1113	amino acid transport
GO012_RS04995	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
GO012_RS05000	COG1012	belongs to the aldehyde dehydrogenase family
GO012_RS05005	COG0579	oxidoreductase
GO012_RS05020	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
GO012_RS05025	COG0625	glutathione transferase activity
GO012_RS05030	COG3775	system Galactitol-specific IIC component
GO012_RS05035	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GO012_RS05040	COG1028	Short-chain dehydrogenase reductase Sdr
GO012_RS05045	COG1070	Carbohydrate kinase
GO012_RS05055	COG1830	Aldolase
GO012_RS05065	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GO012_RS05070	COG0508	dehydrogenase complex catalyzes the overall conversion of
GO012_RS05075	COG0022	dehydrogenase e1 component
GO012_RS05080	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
GO012_RS05085	COG2909	trisaccharide binding
GO012_RS05135	COG0791	NLP P60 protein
GO012_RS05155	COG3639	organic phosphonate transmembrane transporter activity
GO012_RS05165	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
GO012_RS05190	COG3188	usher protein
GO012_RS05205	COG0765	amino acid transport
GO012_RS05210	COG4597	amino acid ABC transporter
GO012_RS05215	COG1126	abc transporter atp-binding protein
GO012_RS05220	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GO012_RS05230	COG0410	ABC transporter
GO012_RS05235	COG0411	ABC transporter
GO012_RS05255	COG4302	ethanolamine ammonia-lyase activity
GO012_RS05260	COG4303	Ethanolamine ammonia lyase large subunit
GO012_RS05280	COG0833	amino acid
GO012_RS05285	COG2040	homocysteine
GO012_RS05290	COG4521	taurine ABC transporter
GO012_RS05295	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
GO012_RS05300	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GO012_RS05305	COG2175	clavaminate synthase activity
GO012_RS05315	COG0113	porphobilinogen synthase activity
GO012_RS05320	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
GO012_RS05325	COG1335	isochorismatase
GO012_RS05330	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
GO012_RS05350	COG1181	Belongs to the D-alanine--D-alanine ligase family
GO012_RS05370	COG1785	Belongs to the alkaline phosphatase family
GO012_RS05380	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
GO012_RS05390	COG3416	Protein conserved in bacteria
GO012_RS05395	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
GO012_RS05405	COG4126	flavin adenine dinucleotide binding
GO012_RS05420	COG1940	carbohydrate kinase activity
GO012_RS05425	COG0419	ATPase involved in DNA repair
GO012_RS05430	COG0420	3'-5' exonuclease activity
GO012_RS05445	COG1114	Component of the transport system for branched-chain amino acids
GO012_RS05455	COG0366	Alpha amylase catalytic
GO012_RS05460	COG0583	DNA-binding transcription factor activity
GO012_RS05465	COG1335	isochorismatase
GO012_RS05475	COG1228	amidohydrolase
GO012_RS05485	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GO012_RS05500	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GO012_RS05505	COG0450	alkyl hydroperoxide reductase
GO012_RS05525	COG1862	Preprotein translocase
GO012_RS05530	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GO012_RS05535	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GO012_RS05555	COG4238	major outer membrane lipoprotein
GO012_RS05565	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GO012_RS05565	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GO012_RS05585	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
GO012_RS05590	COG0667	Aldo Keto reductase
GO012_RS05600	COG0142	geranyltranstransferase activity
GO012_RS05620	COG0693	protein deglycase activity
GO012_RS05625	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
GO012_RS05635	COG2814	Major facilitator Superfamily
GO012_RS05640	COG0673	inositol 2-dehydrogenase activity
GO012_RS05655	COG1053	succinate dehydrogenase
GO012_RS05670	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
GO012_RS05675	COG1414	Transcriptional regulator
GO012_RS05690	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
GO012_RS05695	COG1845	cytochrome c oxidase, subunit III
GO012_RS05700	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
GO012_RS05705	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
GO012_RS05710	COG2223	nitrite transmembrane transporter activity
GO012_RS05715	COG3056	Lipoprotein
GO012_RS05720	COG0271	Belongs to the BolA IbaG family
GO012_RS05745	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
GO012_RS05750	COG0776	regulation of translation
GO012_RS05755	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GO012_RS05760	COG1555	photosystem II stabilization
GO012_RS05765	COG0824	Thioesterase
GO012_RS05775	COG4533	DNA binding
GO012_RS05790	COG1522	sequence-specific DNA binding
GO012_RS05795	COG1132	(ABC) transporter
GO012_RS05800	COG1132	(ABC) transporter
GO012_RS05805	COG0347	Belongs to the P(II) protein family
GO012_RS05810	COG0004	ammonium transporteR
GO012_RS05815	COG1946	Acyl-CoA thioesterase
GO012_RS05820	COG3126	Type III secretion system lipoprotein chaperone (YscW)
GO012_RS05825	COG3695	enzyme binding
GO012_RS05855	COG2364	Membrane
GO012_RS05870	COG4943	cyclic-guanylate-specific phosphodiesterase activity
GO012_RS05880	COG2182	Extracellular solute-binding protein
GO012_RS05885	COG1175	transmembrane transport
GO012_RS05890	COG3833	ABC-type maltose transport systems, permease component
GO012_RS05895	COG3867	Arabinogalactan endo-beta-1,4-galactanase
GO012_RS05900	COG1874	Beta-galactosidase
GO012_RS05945	COG0110	maltose O-acetyltransferase activity
GO012_RS05960	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GO012_RS05965	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GO012_RS05970	COG1309	transcriptional regulator
GO012_RS05975	COG1196	nuclear chromosome segregation
GO012_RS05975	COG3264	Mechanosensitive ion channel
GO012_RS05990	COG3923	Primosomal replication protein n
GO012_RS05995	COG2832	Protein of unknown function (DUF454)
GO012_RS06035	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GO012_RS06040	COG4651	solute:proton antiporter activity
GO012_RS06040	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
GO012_RS06045	COG2223	nitrite transmembrane transporter activity
GO012_RS06055	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
GO012_RS06060	COG3735	TraB family
GO012_RS06075	COG1585	Membrane protein implicated in regulation of membrane protease activity
GO012_RS06080	COG0330	HflC and HflK could
GO012_RS06085	COG4619	ABC transporter
GO012_RS06090	COG0390	transport system, permease component
GO012_RS06095	COG3118	belongs to the thioredoxin family
GO012_RS06100	COG0300	oxidoreductase activity
GO012_RS06105	COG2755	lipolytic protein G-D-S-L family
GO012_RS06110	COG4181	ATPase activity
GO012_RS06115	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
GO012_RS06145	COG3960	tartronate-semialdehyde synthase activity
GO012_RS06150	COG3622	Belongs to the hyi family
GO012_RS06155	COG2084	Dehydrogenase
GO012_RS06165	COG1953	Uracil, thiamine, allantoin
GO012_RS06175	COG2233	PERMEase
GO012_RS06180	COG1929	Belongs to the glycerate kinase type-1 family
GO012_RS06185	COG3257	ureidoglycine aminohydrolase activity
GO012_RS06190	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GO012_RS06195	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
GO012_RS06200	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
GO012_RS06205	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
GO012_RS06215	COG0549	Belongs to the carbamate kinase family
GO012_RS06220	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
GO012_RS06225	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
GO012_RS06240	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
GO012_RS06260	COG1988	membrane-bound metal-dependent
GO012_RS06265	COG2501	S4 domain
GO012_RS06310	COG3539	Fimbrial protein
GO012_RS06315	COG3121	Chaperone
GO012_RS06320	COG3188	usher protein
GO012_RS06335	COG1560	Kdo2-lipid A biosynthetic process
GO012_RS06345	COG3710	Transcriptional regulator
GO012_RS06350	COG0531	amino acid
GO012_RS06355	COG1982	Orn Lys Arg decarboxylase major
GO012_RS06360	COG3104	oligopeptide transport
GO012_RS06390	COG0673	inositol 2-dehydrogenase activity
GO012_RS06405	COG1129	ABC transporter
GO012_RS06410	COG4211	Belongs to the binding-protein-dependent transport system permease family
GO012_RS06455	COG1566	PFAM secretion protein HlyD family protein
GO012_RS06460	COG1120	ATPase activity
GO012_RS06465	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GO012_RS06485	COG1473	amidohydrolase
GO012_RS06490	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GO012_RS06495	COG0667	Aldo Keto reductase
GO012_RS06540	COG0531	amino acid
GO012_RS06550	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GO012_RS06555	COG1012	belongs to the aldehyde dehydrogenase family
GO012_RS06570	COG1113	amino acid transport
GO012_RS06575	COG2211	Major facilitator Superfamily
GO012_RS06585	COG0673	inositol 2-dehydrogenase activity
GO012_RS06600	COG0668	transmembrane transport
GO012_RS06605	COG0477	Major facilitator Superfamily
GO012_RS06620	COG3933	PFAM sigma-54 factor interaction domain-containing protein
GO012_RS06620	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
GO012_RS06625	COG2222	sugar isomerase
GO012_RS06630	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
GO012_RS06635	COG3716	PTS system mannose fructose sorbose family IID component
GO012_RS06645	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GO012_RS06655	COG0778	Nitroreductase
GO012_RS06660	COG2315	Protein conserved in bacteria
GO012_RS06705	COG3698	Phosphodiester glycosidase
GO012_RS06725	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GO012_RS06730	COG4608	Belongs to the ABC transporter superfamily
GO012_RS06745	COG0697	spore germination
GO012_RS06760	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
GO012_RS06765	COG0765	amino acid transport
GO012_RS06770	COG4215	(ABC) transporter
GO012_RS06780	COG4221	oxidoreductase activity
GO012_RS06795	COG4608	Belongs to the ABC transporter superfamily
GO012_RS06800	COG0444	Belongs to the ABC transporter superfamily
GO012_RS06805	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GO012_RS06810	COG0601	transmembrane transport
GO012_RS06815	COG0747	negative chemotaxis
GO012_RS06840	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
GO012_RS06850	COG0668	transmembrane transport
GO012_RS06855	COG0583	DNA-binding transcription factor activity
GO012_RS06865	COG1028	Short-chain dehydrogenase reductase Sdr
GO012_RS06875	COG1172	Belongs to the binding-protein-dependent transport system permease family
GO012_RS06880	COG1129	ABC transporter
GO012_RS06890	COG1879	ABC-type sugar transport system periplasmic component
GO012_RS06895	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
GO012_RS06900	COG2390	Transcriptional regulator
GO012_RS06905	COG3959	Transketolase, thiamine diphosphate binding domain
GO012_RS06910	COG3958	Transketolase
GO012_RS06915	COG2977	Belongs to the P-Pant transferase superfamily
GO012_RS06920	COG4771	TonB-dependent receptor
GO012_RS06925	COG2382	esterase
GO012_RS06930	COG3251	PFAM MbtH domain protein
GO012_RS06935	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
GO012_RS06935	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GO012_RS06940	COG1120	ATPase activity
GO012_RS06945	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GO012_RS06950	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GO012_RS06960	COG4592	Periplasmic binding protein
GO012_RS06965	COG1169	isochorismate synthase
GO012_RS06970	COG1021	2,3-dihydroxybenzoate-AMP ligase
GO012_RS06975	COG1535	isochorismatase
GO012_RS06975	COG3433	isochorismatase activity
GO012_RS06980	COG1028	Short-chain dehydrogenase reductase Sdr
GO012_RS06990	COG1966	Carbon starvation protein
GO012_RS06995	COG2879	small protein
GO012_RS07010	COG1028	Short-chain dehydrogenase reductase Sdr
GO012_RS07015	COG0371	Dehydrogenase
GO012_RS07020	COG1129	ABC transporter
GO012_RS07025	COG1172	Belongs to the binding-protein-dependent transport system permease family
GO012_RS07055	COG2271	Major facilitator Superfamily
GO012_RS07060	COG0483	inositol monophosphate 1-phosphatase activity
GO012_RS07070	COG0402	S-adenosylhomocysteine deaminase activity
GO012_RS07080	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
GO012_RS07095	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GO012_RS07105	COG1172	Belongs to the binding-protein-dependent transport system permease family
GO012_RS07110	COG1172	Belongs to the binding-protein-dependent transport system permease family
GO012_RS07115	COG1129	ABC transporter
GO012_RS07140	COG0436	Aminotransferase
GO012_RS07145	COG1475	DNA binding
GO012_RS07150	COG3969	phosphoadenosine phosphosulfate
GO012_RS07155	COG0583	DNA-binding transcription factor activity
GO012_RS07160	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
GO012_RS07165	COG0450	alkyl hydroperoxide reductase
GO012_RS07175	COG0589	response to stress
GO012_RS07180	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
GO012_RS07185	COG3719	Belongs to the RNase T2 family
GO012_RS07190	COG3069	C4-dicarboxylate transmembrane transporter activity
GO012_RS07200	COG1278	Cold shock
GO012_RS07210	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
GO012_RS07215	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
GO012_RS07225	COG0583	DNA-binding transcription factor activity
GO012_RS07240	COG1686	Belongs to the peptidase S11 family
GO012_RS07245	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
GO012_RS07250	COG0772	Belongs to the SEDS family
GO012_RS07255	COG0768	penicillin binding
GO012_RS07265	COG0799	negative regulation of ribosome biogenesis
GO012_RS07280	COG1466	dna polymerase III delta subunit
GO012_RS07295	COG2888	peptidyl-tyrosine sulfation
GO012_RS07310	COG1126	abc transporter atp-binding protein
GO012_RS07315	COG0765	amino acid transport
GO012_RS07320	COG0765	amino acid transport
GO012_RS07335	COG4535	Mg2 and Co2 transporter CorC
GO012_RS07345	COG1702	phosphate starvation-inducible protein PhoH
GO012_RS07355	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GO012_RS07395	COG0367	asparagine synthase
GO012_RS07400	COG0647	UMP catabolic process
GO012_RS07405	COG1846	Transcriptional regulator
GO012_RS07405	COG1940	carbohydrate kinase activity
GO012_RS07410	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
GO012_RS07445	COG0477	Major facilitator Superfamily
GO012_RS07450	COG0735	belongs to the Fur family
GO012_RS07465	COG0596	Alpha beta hydrolase
GO012_RS07475	COG0033	Phosphoglucomutase
GO012_RS07485	COG0745	RESPONSE REGULATOR receiver
GO012_RS07490	COG2205	protein histidine kinase activity
GO012_RS07520	COG0415	Belongs to the DNA photolyase family
GO012_RS07530	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
GO012_RS07535	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
GO012_RS07540	COG1984	allophanate hydrolase subunit 2
GO012_RS07575	COG2009	succinate dehydrogenase
GO012_RS07580	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
GO012_RS07585	COG1053	succinate dehydrogenase
GO012_RS07590	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
GO012_RS07595	COG0567	Dehydrogenase, E1 component
GO012_RS07600	COG0508	dehydrogenase complex catalyzes the overall conversion of
GO012_RS07610	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
GO012_RS07620	COG1271	oxidase subunit
GO012_RS07625	COG1294	oxidase, subunit
GO012_RS07630	COG4890	Cyd operon protein YbgT
GO012_RS07635	COG3790	cyd operon protein YbgE
GO012_RS07640	COG0824	Thioesterase
GO012_RS07645	COG0811	peptide transport
GO012_RS07650	COG0848	biopolymer transport protein
GO012_RS07655	COG3064	Membrane
GO012_RS07665	COG2885	chlorophyll binding
GO012_RS07670	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
GO012_RS07715	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
GO012_RS07720	COG3201	nicotinamide mononucleotide transporter
GO012_RS07735	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
GO012_RS07745	COG2017	converts alpha-aldose to the beta-anomer
GO012_RS07755	COG1085	galactose-1-phosphate uridylyltransferase
GO012_RS07765	COG1119	ATPase activity
GO012_RS07770	COG3585	molybdate ion transport
GO012_RS07770	COG2005	Transcriptional regulator
GO012_RS07780	COG0725	ABC transporter, periplasmic molybdate-binding protein
GO012_RS07785	COG4149	molybdate abc transporter
GO012_RS07790	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
GO012_RS07795	COG0561	phosphatase activity
GO012_RS07820	COG2200	EAL domain
GO012_RS07825	COG0789	Transcriptional regulator
GO012_RS07855	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GO012_RS07860	COG0589	response to stress
GO012_RS07870	COG4677	pectinesterase activity
GO012_RS07905	COG1881	PFAM PEBP family protein
GO012_RS07910	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
GO012_RS07925	COG2226	methyltransferase
GO012_RS07935	COG0410	ABC transporter
GO012_RS07955	COG0642	Histidine kinase
GO012_RS07960	COG0745	RESPONSE REGULATOR receiver
GO012_RS07980	COG0521	Mo-molybdopterin cofactor biosynthetic process
GO012_RS07990	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
GO012_RS07995	COG0314	molybdopterin synthase activity
GO012_RS08000	COG0670	Belongs to the BI1 family
GO012_RS08005	COG0392	lysyltransferase activity
GO012_RS08010	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GO012_RS08015	COG3568	Endonuclease Exonuclease Phosphatase
GO012_RS08025	COG0842	Transport permease protein
GO012_RS08030	COG0842	Transport permease protein
GO012_RS08035	COG1131	(ABC) transporter
GO012_RS08040	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GO012_RS08045	COG1309	transcriptional regulator
GO012_RS08050	COG0583	DNA-binding transcription factor activity
GO012_RS08055	COG2271	Major facilitator Superfamily
GO012_RS08060	COG1028	Short-chain dehydrogenase reductase Sdr
GO012_RS08065	COG3959	Transketolase, thiamine diphosphate binding domain
GO012_RS08070	COG3958	Transketolase
GO012_RS08075	COG0513	Belongs to the DEAD box helicase family
GO012_RS08080	COG1199	ATP-dependent helicase activity
GO012_RS08085	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
GO012_RS08095	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
GO012_RS08105	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
GO012_RS08115	COG0668	transmembrane transport
GO012_RS08120	COG1126	abc transporter atp-binding protein
GO012_RS08125	COG0765	amino acid transport
GO012_RS08130	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GO012_RS08145	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
GO012_RS08150	COG2194	sulfuric ester hydrolase activity
GO012_RS08160	COG1321	iron dependent repressor
GO012_RS08165	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
GO012_RS08170	COG2723	6-phospho-beta-galactosidase activity
GO012_RS08175	COG2188	Transcriptional regulator
GO012_RS08180	COG1376	ErfK ybiS ycfS ynhG family protein
GO012_RS08185	COG2365	Tyrosine phosphatase family
GO012_RS08190	COG0488	(ABC) transporter
GO012_RS08200	COG2271	Major facilitator Superfamily
GO012_RS08205	COG1609	Transcriptional regulator
GO012_RS08215	COG0561	phosphatase activity
GO012_RS08225	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
GO012_RS08230	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
GO012_RS08235	COG0303	'Molybdopterin
GO012_RS08250	COG0747	negative chemotaxis
GO012_RS08270	COG2223	nitrite transmembrane transporter activity
GO012_RS08280	COG2133	pyrroloquinoline quinone binding
GO012_RS08285	COG0625	glutathione transferase activity
GO012_RS08290	COG1686	Belongs to the peptidase S11 family
GO012_RS08295	COG1349	DNA-binding transcription factor activity
GO012_RS08300	COG0671	phosphoesterase, PA-phosphatase related
GO012_RS08305	COG2814	Major facilitator Superfamily
GO012_RS08310	COG0561	phosphatase activity
GO012_RS08315	COG0738	Major facilitator superfamily
GO012_RS08320	COG3226	Transcriptional regulator
GO012_RS08335	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
GO012_RS08345	COG0778	Nitroreductase
GO012_RS08360	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
GO012_RS08365	COG3842	ATPase activity
GO012_RS08370	COG1176	ABC-type spermidine putrescine transport system, permease component I
GO012_RS08375	COG1177	transmembrane transport
GO012_RS08390	COG0745	RESPONSE REGULATOR receiver
GO012_RS08395	COG5002	protein histidine kinase activity
GO012_RS08400	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GO012_RS08405	COG4160	amino acid transport
GO012_RS08410	COG4215	(ABC) transporter
GO012_RS08415	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GO012_RS08420	COG1126	abc transporter atp-binding protein
GO012_RS08430	COG5001	Diguanylate cyclase
GO012_RS08430	COG2203	Gaf domain
GO012_RS08430	COG4251	negative regulation of phosphorylation
GO012_RS08430	COG3706	GGDEF domain
GO012_RS08435	COG3023	N-Acetylmuramoyl-L-alanine amidase
GO012_RS08440	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GO012_RS08445	COG0702	epimerase
GO012_RS08450	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
GO012_RS08455	COG0028	Belongs to the TPP enzyme family
GO012_RS08465	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
GO012_RS08475	COG2431	L-lysine efflux transmembrane transporter activity
GO012_RS08480	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
GO012_RS08485	COG3593	DNA synthesis involved in DNA repair
GO012_RS08490	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GO012_RS08500	COG1278	Cold shock
GO012_RS08510	COG0542	response to heat
GO012_RS08525	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
GO012_RS08530	COG4988	ABC transporter
GO012_RS08535	COG0492	ferredoxin-NADP+ reductase activity
GO012_RS08545	COG1674	ftsk spoiiie
GO012_RS08545	COG1178	ABC-type Fe3 transport system permease component
GO012_RS08555	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
GO012_RS08565	COG0243	molybdopterin cofactor binding
GO012_RS08570	COG0437	4 iron, 4 sulfur cluster binding
GO012_RS08575	COG3302	dmso reductase anchor subunit
GO012_RS08585	COG0477	Major facilitator Superfamily
GO012_RS08590	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
GO012_RS08595	COG1882	Formate acetyltransferase
GO012_RS08600	COG2116	formate transmembrane transporter activity
GO012_RS08605	COG1944	ATP diphosphatase activity
GO012_RS08610	COG2323	membrane
GO012_RS08630	COG0539	negative regulation of cytoplasmic translation
GO012_RS08640	COG2333	competence protein COMEC
GO012_RS08640	COG0658	competence protein
GO012_RS08655	COG3214	Protein conserved in bacteria
GO012_RS08670	COG3173	Aminoglycoside phosphotransferase
GO012_RS08675	COG1434	Gram-negative-bacterium-type cell wall biogenesis
GO012_RS08680	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
GO012_RS08690	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
GO012_RS08700	COG2989	Protein conserved in bacteria
GO012_RS08705	COG3108	Peptidase M15
GO012_RS08710	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GO012_RS08715	COG1448	Aminotransferase
GO012_RS08720	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
GO012_RS08730	COG1522	sequence-specific DNA binding
GO012_RS08740	COG0814	amino acid
GO012_RS08750	COG1473	amidohydrolase
GO012_RS08760	COG0308	aminopeptidase N
GO012_RS08770	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GO012_RS08775	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GO012_RS08780	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
GO012_RS08785	COG0431	NADPH-dependent FMN reductase
GO012_RS08800	COG0633	Ferredoxin
GO012_RS08800	COG3217	Mosc domain protein beta barrel domain protein
GO012_RS08810	COG0488	(ABC) transporter
GO012_RS08815	COG2995	paraquat-inducible protein a
GO012_RS08820	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
GO012_RS08820	COG3008	intermembrane lipid transfer
GO012_RS08825	COG3009	Protein conserved in bacteria
GO012_RS08830	COG3130	regulation of translation
GO012_RS08840	COG1067	ATP-dependent peptidase activity
GO012_RS08865	COG3070	regulator of competence-specific genes
GO012_RS08870	COG1289	transmembrane transporter activity
GO012_RS08875	COG3304	Inner membrane component domain
GO012_RS08880	COG0210	DNA helicase
GO012_RS08890	COG1832	CoA-binding protein
GO012_RS08905	COG1881	PFAM PEBP family protein
GO012_RS08910	COG2207	Transcriptional regulator
GO012_RS08925	COG0670	Belongs to the BI1 family
GO012_RS08940	COG0058	SHG alpha-glucan phosphorylase activity
GO012_RS08950	COG2200	EAL domain
GO012_RS08970	COG3706	GGDEF domain
GO012_RS08975	COG2207	Transcriptional regulator
GO012_RS08985	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GO012_RS08990	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
GO012_RS09000	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GO012_RS09005	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GO012_RS09010	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
GO012_RS09010	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
GO012_RS09010	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GO012_RS09015	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
GO012_RS09020	COG1012	belongs to the aldehyde dehydrogenase family
GO012_RS09025	COG4638	Rieske (2fe-2S)
GO012_RS09030	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
GO012_RS09035	COG0473	3-isopropylmalate dehydrogenase activity
GO012_RS09040	COG0583	DNA-binding transcription factor activity
GO012_RS09045	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GO012_RS09050	COG1012	belongs to the aldehyde dehydrogenase family
GO012_RS09055	COG1396	sequence-specific DNA binding
GO012_RS09055	COG1917	Cupin 2, conserved barrel domain protein
GO012_RS09060	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
GO012_RS09065	COG0174	glutamine synthetase
GO012_RS09070	COG0531	amino acid
GO012_RS09085	COG1028	Short-chain dehydrogenase reductase Sdr
GO012_RS09090	COG1733	regulation of RNA biosynthetic process
GO012_RS09110	COG3729	General stress protein
GO012_RS09120	COG2233	PERMEase
GO012_RS09155	COG1309	transcriptional regulator
GO012_RS09170	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GO012_RS09180	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
GO012_RS09185	COG0672	)-iron permease
GO012_RS09200	COG1702	phosphate starvation-inducible protein PhoH
GO012_RS09215	COG1335	isochorismatase
GO012_RS09225	COG0583	DNA-binding transcription factor activity
GO012_RS09245	COG3381	protein complex oligomerization
GO012_RS09280	COG5645	(Lipo)protein
GO012_RS09295	COG1560	Kdo2-lipid A biosynthetic process
GO012_RS09340	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GO012_RS09360	COG2814	Major facilitator Superfamily
GO012_RS09365	COG0583	DNA-binding transcription factor activity
GO012_RS09370	COG1530	ribonuclease E activity
GO012_RS09385	COG1399	metal-binding, possibly nucleic acid-binding protein
GO012_RS09405	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
GO012_RS09410	COG1028	Short-chain dehydrogenase reductase Sdr
GO012_RS09420	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GO012_RS09425	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
GO012_RS09430	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
GO012_RS09440	COG0470	DNA polymerase III
GO012_RS09445	COG0084	hydrolase, TatD family'
GO012_RS09455	COG0537	adenosine 5'-monophosphoramidase activity
GO012_RS09460	COG5633	Lipoprotein
GO012_RS09485	COG1252	NADH dehydrogenase
GO012_RS09490	COG3134	Outer membrane lipoprotein
GO012_RS09500	COG1309	transcriptional regulator
GO012_RS09510	COG1388	LysM domain
GO012_RS09510	COG1376	ErfK ybiS ycfS ynhG family protein
GO012_RS09515	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
GO012_RS09520	COG4591	ABC-type transport system involved in lipoprotein release permease component
GO012_RS09530	COG4591	ABC-type transport system involved in lipoprotein release permease component
GO012_RS09540	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
GO012_RS09550	COG2390	Transcriptional regulator
GO012_RS09565	COG3395	kinase activity
GO012_RS09580	COG0698	ribose 5-phosphate isomerase
GO012_RS09585	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
GO012_RS09590	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
GO012_RS09595	COG0318	PFAM AMP-dependent synthetase and ligase
GO012_RS09605	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
GO012_RS09610	COG1177	transmembrane transport
GO012_RS09615	COG1176	ABC-type spermidine putrescine transport system, permease component I
GO012_RS09630	COG1943	Transposase
GO012_RS09635	COG2850	peptidyl-arginine hydroxylation
GO012_RS09640	COG2205	protein histidine kinase activity
GO012_RS09660	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
GO012_RS09680	COG1187	pseudouridine synthase activity
GO012_RS09685	COG0538	isocitrate dehydrogenase activity
GO012_RS09690	COG0582	viral genome integration into host DNA
GO012_RS09700	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
GO012_RS09755	COG3344	reverse transcriptase
GO012_RS09775	COG1403	HNH endonuclease
GO012_RS09800	COG3772	lysozyme
GO012_RS09840	COG1802	Transcriptional regulator
GO012_RS09840	COG4626	Terminase
GO012_RS09855	COG0616	signal peptide processing
GO012_RS09940	COG3706	GGDEF domain
GO012_RS09945	COG3300	MHYT domain
GO012_RS09945	COG5001	Diguanylate cyclase
GO012_RS09950	COG0538	isocitrate dehydrogenase activity
GO012_RS09955	COG0640	Transcriptional regulator
GO012_RS09970	COG3813	Protein conserved in bacteria
GO012_RS09975	COG1063	alcohol dehydrogenase
GO012_RS09985	COG3729	General stress protein
GO012_RS09990	COG3685	Protein conserved in bacteria
GO012_RS09995	COG3685	Protein conserved in bacteria
GO012_RS10000	COG3546	catalase activity
GO012_RS10005	COG1271	oxidase subunit
GO012_RS10010	COG1294	oxidase, subunit
GO012_RS10035	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
GO012_RS10040	COG0583	DNA-binding transcription factor activity
GO012_RS10045	COG3706	GGDEF domain
GO012_RS10050	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
GO012_RS10060	COG1560	Kdo2-lipid A biosynthetic process
GO012_RS10070	COG3182	Iron-regulated membrane protein
GO012_RS10090	COG2203	Gaf domain
GO012_RS10090	COG2199	diguanylate cyclase activity
GO012_RS10095	COG3042	response to heat
GO012_RS10100	COG3189	MarR family transcriptional regulator
GO012_RS10105	COG1683	Conserved Protein
GO012_RS10110	COG0504	CTP synthase activity
GO012_RS10115	COG2807	transmembrane transport
GO012_RS10120	COG2207	Transcriptional regulator
GO012_RS10130	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
GO012_RS10135	COG0859	PFAM glycosyl transferase family 9
GO012_RS10145	COG3344	reverse transcriptase
GO012_RS10150	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
GO012_RS10155	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
GO012_RS10160	COG0583	DNA-binding transcription factor activity
GO012_RS10165	COG1028	Short-chain dehydrogenase reductase Sdr
GO012_RS10185	COG0386	Belongs to the glutathione peroxidase family
GO012_RS10200	COG2766	serine protein kinase
GO012_RS10205	COG3713	MltA-interacting MipA family protein
GO012_RS10210	COG0656	L-ascorbic acid biosynthetic process
GO012_RS10220	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
GO012_RS10230	COG3139	Protein of unknown function (DUF1315)
GO012_RS10235	COG1403	HNH endonuclease
GO012_RS10245	COG1335	isochorismatase
GO012_RS10250	COG0252	asparaginase activity
GO012_RS10255	COG0616	signal peptide processing
GO012_RS10260	COG0778	Nitroreductase
GO012_RS10270	COG0709	Synthesizes selenophosphate from selenide and ATP
GO012_RS10275	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
GO012_RS10285	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
GO012_RS10290	COG0494	nUDIX hydrolase
GO012_RS10295	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
GO012_RS10300	COG2897	thiosulfate sulfurtransferase activity
GO012_RS10305	COG4136	ATPase activity
GO012_RS10310	COG4135	transport system, permease component
GO012_RS10315	COG4134	Bacterial extracellular solute-binding protein
GO012_RS10320	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
GO012_RS10325	COG0398	Pfam SNARE associated Golgi protein
GO012_RS10330	COG0398	Pfam SNARE associated Golgi protein
GO012_RS10335	COG0708	Exodeoxyribonuclease III
GO012_RS10345	COG3138	arginine N-succinyltransferase
GO012_RS10355	COG3724	N-succinylarginine dihydrolase activity
GO012_RS10365	COG3678	ATP-independent chaperone mediated protein folding
GO012_RS10370	COG0322	excinuclease ABC activity
GO012_RS10380	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GO012_RS10385	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GO012_RS10390	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GO012_RS10395	COG1447	Phosphotransferase system cellobiose-specific component IIA
GO012_RS10400	COG2169	Transcriptional regulator
GO012_RS10400	COG1917	Cupin 2, conserved barrel domain protein
GO012_RS10405	COG1486	melibiose metabolic process
GO012_RS10415	COG0753	catalase activity
GO012_RS10430	COG1988	membrane-bound metal-dependent
GO012_RS10435	COG1028	Short-chain dehydrogenase reductase Sdr
GO012_RS10440	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GO012_RS10450	COG1607	acyl-coa hydrolase
GO012_RS10475	COG3047	cAMP biosynthetic process
GO012_RS10485	COG4774	siderophore transport
GO012_RS10540	COG0134	indole-3-glycerol-phosphate synthase activity
GO012_RS10540	COG0135	phosphoribosylanthranilate isomerase activity
GO012_RS10545	COG0512	Glutamine amidotransferase of anthranilate synthase
GO012_RS10545	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
GO012_RS10550	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
GO012_RS10560	COG0009	L-threonylcarbamoyladenylate synthase
GO012_RS10570	COG0583	DNA-binding transcription factor activity
GO012_RS10575	COG1187	pseudouridine synthase activity
GO012_RS10580	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
GO012_RS10585	COG1028	Short-chain dehydrogenase reductase Sdr
GO012_RS10595	COG0616	signal peptide processing
GO012_RS10605	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
GO012_RS10620	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
GO012_RS10630	COG0671	phosphoesterase, PA-phosphatase related
GO012_RS10635	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
GO012_RS10640	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
GO012_RS10650	COG0023	Translation Initiation Factor
GO012_RS10660	COG1349	DNA-binding transcription factor activity
GO012_RS10675	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
GO012_RS10675	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
GO012_RS10680	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
GO012_RS10690	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
GO012_RS10705	COG4171	peptide transport system, permease
GO012_RS10710	COG4168	peptide transport system, permease
GO012_RS10720	COG0702	epimerase
GO012_RS10735	COG1473	amidohydrolase
GO012_RS10745	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
GO012_RS10750	COG1842	Phage shock protein A
GO012_RS10760	COG1983	PspC domain protein
GO012_RS10770	COG3106	COG3106 Predicted ATPase
GO012_RS10780	COG0583	DNA-binding transcription factor activity
GO012_RS10785	COG1486	melibiose metabolic process
GO012_RS10790	COG3283	Transcriptional regulator of aromatic amino acids metabolism
GO012_RS10795	COG3180	Ammonia monooxygenase
GO012_RS10800	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
GO012_RS10805	COG4948	Mandelate Racemase Muconate Lactonizing
GO012_RS10810	COG2866	Carboxypeptidase
GO012_RS10815	COG4166	transmembrane transport
GO012_RS10880	COG0656	L-ascorbic acid biosynthetic process
GO012_RS10890	COG5002	protein histidine kinase activity
GO012_RS10890	COG2205	protein histidine kinase activity
GO012_RS10890	COG0784	Response regulator, receiver
GO012_RS10930	COG3706	GGDEF domain
GO012_RS10930	COG0745	RESPONSE REGULATOR receiver
GO012_RS10950	COG0583	DNA-binding transcription factor activity
GO012_RS10955	COG1028	Short-chain dehydrogenase reductase Sdr
GO012_RS10960	COG1078	dGTPase activity
GO012_RS10965	COG0693	protein deglycase activity
GO012_RS10990	COG2885	chlorophyll binding
GO012_RS11015	COG1705	Flagellar rod assembly protein muramidase FlgJ
GO012_RS11015	COG1388	LysM domain
GO012_RS11085	COG1028	Short-chain dehydrogenase reductase Sdr
GO012_RS11090	COG1309	transcriptional regulator
GO012_RS11095	COG1028	Short-chain dehydrogenase reductase Sdr
GO012_RS11115	COG0583	DNA-binding transcription factor activity
GO012_RS11145	COG0436	Aminotransferase
GO012_RS11160	COG2011	ABC-type metal ion transport system permease component
GO012_RS11165	COG1448	Aminotransferase
GO012_RS11175	COG1522	sequence-specific DNA binding
GO012_RS11180	COG1113	amino acid transport
GO012_RS11195	COG0673	inositol 2-dehydrogenase activity
GO012_RS11200	COG1349	DNA-binding transcription factor activity
GO012_RS11210	COG0513	Belongs to the DEAD box helicase family
GO012_RS11220	COG0589	response to stress
GO012_RS11230	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
GO012_RS11235	COG1013	pyruvate-flavodoxin oxidoreductase activity
GO012_RS11235	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
GO012_RS11235	COG0674	pyruvate-flavodoxin oxidoreductase activity
GO012_RS11235	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GO012_RS11240	COG3042	response to heat
GO012_RS11245	COG3187	Heat shock protein
GO012_RS11250	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GO012_RS11255	COG0586	Pfam SNARE associated Golgi protein
GO012_RS11260	COG2911	Protein conserved in bacteria
GO012_RS11270	COG3784	Protein of unknown function (DUF1318)
GO012_RS11275	COG2207	Transcriptional regulator
GO012_RS11280	COG1012	belongs to the aldehyde dehydrogenase family
GO012_RS11300	COG1012	belongs to the aldehyde dehydrogenase family
GO012_RS11300	COG2030	dehydratase
GO012_RS11305	COG3396	Phenylacetate-CoA oxygenase
GO012_RS11310	COG3460	Phenylacetate-CoA oxygenase
GO012_RS11315	COG3396	Phenylacetate-CoA oxygenase
GO012_RS11320	COG2151	metal-sulfur cluster biosynthetic enzyme
GO012_RS11325	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
GO012_RS11330	COG1024	Enoyl-CoA hydratase
GO012_RS11335	COG1024	Enoyl-CoA hydratase
GO012_RS11340	COG1250	3-hydroxyacyl-CoA dehydrogenase
GO012_RS11345	COG2050	protein possibly involved in aromatic compounds catabolism
GO012_RS11350	COG0183	Belongs to the thiolase family
GO012_RS11355	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
GO012_RS11360	COG3327	negative regulation of DNA-templated transcription, initiation
GO012_RS11365	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
GO012_RS11380	COG1643	Atp-dependent helicase
GO012_RS11390	COG1538	Outer membrane efflux protein
GO012_RS11410	COG0583	DNA-binding transcription factor activity
GO012_RS11415	COG0667	Aldo Keto reductase
GO012_RS11420	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
GO012_RS11425	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
GO012_RS11430	COG3138	arginine N-succinyltransferase
GO012_RS11435	COG1012	belongs to the aldehyde dehydrogenase family
GO012_RS11440	COG3724	N-succinylarginine dihydrolase activity
GO012_RS11445	COG2988	succinylglutamate desuccinylase activity
GO012_RS11450	COG1113	amino acid transport
GO012_RS11455	COG0477	Major facilitator Superfamily
GO012_RS11460	COG1434	Gram-negative-bacterium-type cell wall biogenesis
GO012_RS11465	COG1012	belongs to the aldehyde dehydrogenase family
GO012_RS11470	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
GO012_RS11475	COG0401	homolog of Blt101
GO012_RS11480	COG5562	phage envelope protein
GO012_RS11485	COG0425	Belongs to the sulfur carrier protein TusA family
GO012_RS11490	COG2391	methyltransferase activity
GO012_RS11515	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
GO012_RS11520	COG1263	PTS System
GO012_RS11520	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GO012_RS11525	COG1609	Transcriptional regulator
GO012_RS11530	COG5339	Protein conserved in bacteria
GO012_RS11535	COG1482	cell wall glycoprotein biosynthetic process
GO012_RS11540	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
GO012_RS11540	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
GO012_RS11545	COG0114	fumarate hydratase activity
GO012_RS11555	COG2205	protein histidine kinase activity
GO012_RS11565	COG0745	RESPONSE REGULATOR receiver
GO012_RS11570	COG3136	membrane protein required for alginate biosynthesis
GO012_RS11580	COG0531	amino acid
GO012_RS11590	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
GO012_RS11595	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
GO012_RS11610	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GO012_RS11615	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
GO012_RS11625	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
GO012_RS11630	COG1473	amidohydrolase
GO012_RS11640	COG0583	DNA-binding transcription factor activity
GO012_RS11645	COG2840	Smr protein MutS2
GO012_RS11650	COG1414	Transcriptional regulator
GO012_RS11660	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
GO012_RS11665	COG0183	Belongs to the thiolase family
GO012_RS11675	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
GO012_RS11680	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
GO012_RS11690	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
GO012_RS11690	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
GO012_RS11700	COG1053	succinate dehydrogenase
GO012_RS11710	COG4565	transcriptional regulatory protein
GO012_RS11715	COG3290	protein histidine kinase activity
GO012_RS11740	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
GO012_RS11750	COG0679	Auxin Efflux Carrier
GO012_RS11780	COG0628	permease
GO012_RS11800	COG3591	Belongs to the peptidase S1B family
GO012_RS11810	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
GO012_RS11815	COG2814	Major facilitator Superfamily
GO012_RS11820	COG0583	DNA-binding transcription factor activity
GO012_RS11825	COG1940	carbohydrate kinase activity
GO012_RS11830	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
GO012_RS11845	COG3302	dmso reductase anchor subunit
GO012_RS11850	COG0437	4 iron, 4 sulfur cluster binding
GO012_RS11855	COG0243	molybdopterin cofactor binding
GO012_RS11870	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GO012_RS11885	COG2271	Major facilitator Superfamily
GO012_RS11890	COG0246	Mannitol dehydrogenase
GO012_RS11895	COG0589	response to stress
GO012_RS11900	COG1802	Transcriptional regulator
GO012_RS11905	COG4221	oxidoreductase activity
GO012_RS11920	COG2207	Transcriptional regulator
GO012_RS11925	COG2135	peptidase activity
GO012_RS11935	COG2197	response regulator
GO012_RS11940	COG0071	Belongs to the small heat shock protein (HSP20) family
GO012_RS11945	COG1546	Belongs to the CinA family
GO012_RS11950	COG2200	EAL domain
GO012_RS11965	COG3708	Transcriptional regulator
GO012_RS11965	COG2207	Transcriptional regulator
GO012_RS11970	COG2610	gluconate transmembrane transporter activity
GO012_RS11975	COG3622	Belongs to the hyi family
GO012_RS11980	COG0235	Class ii aldolase
GO012_RS11985	COG3395	kinase activity
GO012_RS11990	COG2084	Dehydrogenase
GO012_RS11995	COG1349	DNA-binding transcription factor activity
GO012_RS12010	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
GO012_RS12015	COG2223	nitrite transmembrane transporter activity
GO012_RS12050	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
GO012_RS12070	COG0411	ABC transporter
GO012_RS12085	COG2814	Major facilitator Superfamily
GO012_RS12090	COG0697	spore germination
GO012_RS12100	COG4977	sequence-specific DNA binding
GO012_RS12105	COG1846	Transcriptional regulator
GO012_RS12125	COG2271	Major facilitator Superfamily
GO012_RS12130	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GO012_RS12135	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GO012_RS12145	COG3395	kinase activity
GO012_RS12150	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
GO012_RS12155	COG1349	DNA-binding transcription factor activity
GO012_RS12160	COG0039	L-malate dehydrogenase activity
GO012_RS12170	COG0583	DNA-binding transcription factor activity
GO012_RS12175	COG1012	belongs to the aldehyde dehydrogenase family
GO012_RS12190	COG2199	diguanylate cyclase activity
GO012_RS12255	COG0477	Major facilitator Superfamily
GO012_RS12265	COG0477	Major facilitator Superfamily
GO012_RS12275	COG2070	2-Nitropropane dioxygenase
GO012_RS12280	COG2011	ABC-type metal ion transport system permease component
GO012_RS12315	COG2207	Transcriptional regulator
GO012_RS12345	COG2233	PERMEase
GO012_RS12350	COG3195	allantoin biosynthetic process
GO012_RS12350	COG3648	Uricase
GO012_RS12355	COG2351	hydroxyisourate hydrolase activity
GO012_RS12360	COG1396	sequence-specific DNA binding
GO012_RS12365	COG3550	peptidyl-serine autophosphorylation
GO012_RS12380	COG3188	usher protein
GO012_RS12400	COG0024	Methionine aminopeptidase
GO012_RS12415	COG5001	Diguanylate cyclase
GO012_RS12415	COG3300	MHYT domain
GO012_RS12420	COG2819	hydrolase of the alpha beta superfamily
GO012_RS12430	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
GO012_RS12430	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
GO012_RS12435	COG2814	Major facilitator Superfamily
GO012_RS12445	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GO012_RS12445	COG1263	PTS System
GO012_RS12450	COG2186	Transcriptional regulator
GO012_RS12470	COG3835	regulator
GO012_RS12475	COG1929	Belongs to the glycerate kinase type-1 family
GO012_RS12520	COG0738	Major facilitator superfamily
GO012_RS12525	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GO012_RS12530	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
GO012_RS12535	COG1349	DNA-binding transcription factor activity
GO012_RS12565	COG0667	Aldo Keto reductase
GO012_RS12575	COG0456	acetyltransferase
GO012_RS12575	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
GO012_RS12590	COG1840	ABC-type Fe3 transport system, periplasmic component
GO012_RS12600	COG1652	LysM domain
GO012_RS12630	COG1609	Transcriptional regulator
GO012_RS12640	COG1172	Belongs to the binding-protein-dependent transport system permease family
GO012_RS12655	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GO012_RS12665	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GO012_RS12670	COG0583	DNA-binding transcription factor activity
GO012_RS12675	COG0583	DNA-binding transcription factor activity
GO012_RS12695	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GO012_RS12710	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
GO012_RS12715	COG3037	sugar-specific permease SgaT UlaA
GO012_RS12725	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GO012_RS12730	COG1609	Transcriptional regulator
GO012_RS12740	COG2223	nitrite transmembrane transporter activity
GO012_RS12770	COG0477	Major facilitator Superfamily
GO012_RS12775	COG4529	Protein conserved in bacteria
GO012_RS12780	COG1902	pentaerythritol trinitrate reductase activity
GO012_RS12790	COG0583	DNA-binding transcription factor activity
GO012_RS12795	COG2070	2-Nitropropane dioxygenase
GO012_RS12805	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
GO012_RS12860	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
GO012_RS12880	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GO012_RS12895	COG2207	Transcriptional regulator
GO012_RS12905	COG0596	Alpha beta hydrolase
GO012_RS12940	COG1953	Uracil, thiamine, allantoin
GO012_RS12945	COG0402	S-adenosylhomocysteine deaminase activity
GO012_RS12950	COG3706	GGDEF domain
GO012_RS12965	COG0673	inositol 2-dehydrogenase activity
GO012_RS12975	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
GO012_RS12980	COG1116	anion transmembrane transporter activity
GO012_RS12985	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GO012_RS12990	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
GO012_RS12995	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
GO012_RS13000	COG0076	glutamate decarboxylase activity
GO012_RS13015	COG2205	protein histidine kinase activity
GO012_RS13020	COG0745	RESPONSE REGULATOR receiver
GO012_RS13025	COG0596	Alpha beta hydrolase
GO012_RS13065	COG0518	GMP synthase (glutamine-hydrolyzing) activity
GO012_RS13065	COG0519	Catalyzes the synthesis of GMP from XMP
GO012_RS13085	COG0583	DNA-binding transcription factor activity
GO012_RS13095	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
GO012_RS13100	COG1285	pathogenesis
GO012_RS13105	COG2814	Major facilitator Superfamily
GO012_RS13110	COG1447	Phosphotransferase system cellobiose-specific component IIA
GO012_RS13115	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GO012_RS13145	COG0583	DNA-binding transcription factor activity
GO012_RS13150	COG0243	molybdopterin cofactor binding
GO012_RS13155	COG3781	membrane
GO012_RS13160	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
GO012_RS13175	COG1764	response to oxidative stress
GO012_RS13180	COG3111	PFAM Bacterial OB fold (BOF) protein
GO012_RS13190	COG2323	membrane
GO012_RS13200	COG0366	Alpha amylase catalytic
GO012_RS13210	COG3685	Protein conserved in bacteria
GO012_RS13220	COG3729	General stress protein
GO012_RS13225	COG1028	Short-chain dehydrogenase reductase Sdr
GO012_RS13260	COG0488	(ABC) transporter
GO012_RS13275	COG1064	alcohol dehydrogenase
GO012_RS13280	COG0747	negative chemotaxis
GO012_RS13300	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GO012_RS13310	COG2814	Major facilitator Superfamily
GO012_RS13320	COG2326	polyphosphate kinase activity
GO012_RS13335	COG2864	formate dehydrogenase
GO012_RS13340	COG0437	4 iron, 4 sulfur cluster binding
GO012_RS13365	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
GO012_RS13375	COG3485	protocatechuate 3,4-dioxygenase
GO012_RS13380	COG4829	muconolactone delta-isomerase
GO012_RS13385	COG4948	Mandelate Racemase Muconate Lactonizing
GO012_RS13390	COG1414	Transcriptional regulator
GO012_RS13405	COG2223	nitrite transmembrane transporter activity
GO012_RS13410	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
GO012_RS13415	COG1140	nitrate reductase beta subunit
GO012_RS13420	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
GO012_RS13425	COG2181	nitrate reductase activity
GO012_RS13430	COG2162	N-hydroxyarylamine O-acetyltransferase activity
GO012_RS13435	COG1178	ABC-type Fe3 transport system permease component
GO012_RS13440	COG1840	ABC-type Fe3 transport system, periplasmic component
GO012_RS13445	COG3842	ATPase activity
GO012_RS13450	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
GO012_RS13460	COG0625	glutathione transferase activity
GO012_RS13470	COG1126	abc transporter atp-binding protein
GO012_RS13475	COG0765	amino acid transport
GO012_RS13490	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GO012_RS13500	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GO012_RS13530	COG4772	TonB-dependent receptor
GO012_RS13535	COG1228	amidohydrolase
GO012_RS13540	COG3691	Protein conserved in bacteria
GO012_RS13550	COG2130	NADP-dependent
GO012_RS13560	COG1247	-acetyltransferase
GO012_RS13565	COG3238	Protein conserved in bacteria
GO012_RS13575	COG0747	negative chemotaxis
GO012_RS13580	COG1012	belongs to the aldehyde dehydrogenase family
GO012_RS13615	COG1012	belongs to the aldehyde dehydrogenase family
GO012_RS13620	COG1177	transmembrane transport
GO012_RS13625	COG1176	ABC-type spermidine putrescine transport system, permease component I
GO012_RS13630	COG3842	ATPase activity
GO012_RS13635	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
GO012_RS13640	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GO012_RS13645	COG1271	oxidase subunit
GO012_RS13650	COG1294	oxidase, subunit
GO012_RS13670	COG0826	peptidase U32
GO012_RS13680	COG1396	sequence-specific DNA binding
GO012_RS13685	COG3135	benzoate transporter
GO012_RS13690	COG2207	Transcriptional regulator
GO012_RS13690	COG3708	Transcriptional regulator
GO012_RS13695	COG0697	spore germination
GO012_RS13705	COG0500	methyltransferase
GO012_RS13710	COG1275	C4-dicarboxylate transporter malic acid transport protein
GO012_RS13715	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
GO012_RS13720	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GO012_RS13735	COG2272	Belongs to the type-B carboxylesterase lipase family
GO012_RS13740	COG5383	Protein conserved in bacteria
GO012_RS13745	COG3485	protocatechuate 3,4-dioxygenase
GO012_RS13750	COG3485	protocatechuate 3,4-dioxygenase
GO012_RS13775	COG3038	cytochrome b561
GO012_RS13790	COG1733	regulation of RNA biosynthetic process
GO012_RS13795	COG2814	Major facilitator Superfamily
GO012_RS13805	COG0673	inositol 2-dehydrogenase activity
GO012_RS13815	COG2723	6-phospho-beta-galactosidase activity
GO012_RS13850	COG4659	FMN binding
GO012_RS13860	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
GO012_RS13870	COG0625	glutathione transferase activity
GO012_RS13875	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
GO012_RS13890	COG3895	Periplasmic Protein
GO012_RS13900	COG3133	Outer membrane lipoprotein
GO012_RS13905	COG3706	GGDEF domain
GO012_RS13920	COG1566	PFAM secretion protein HlyD family protein
GO012_RS13925	COG1289	transmembrane transporter activity
GO012_RS13930	COG2032	superoxide dismutase activity
GO012_RS13935	COG4989	oxidoreductase activity
GO012_RS13940	COG3313	Fe-S protein
GO012_RS13945	COG1309	transcriptional regulator
GO012_RS13950	COG1902	pentaerythritol trinitrate reductase activity
GO012_RS13955	COG0346	lactoylglutathione lyase activity
GO012_RS13965	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
GO012_RS13970	COG0791	NLP P60 protein
GO012_RS13980	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
GO012_RS13985	COG2814	Major facilitator Superfamily
GO012_RS14000	COG0583	DNA-binding transcription factor activity
GO012_RS14005	COG2814	Major facilitator Superfamily
GO012_RS14010	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
GO012_RS14015	COG0307	riboflavin synthase, alpha
GO012_RS14060	COG0300	oxidoreductase activity
GO012_RS14080	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
GO012_RS14110	COG1349	DNA-binding transcription factor activity
GO012_RS14115	COG0346	lactoylglutathione lyase activity
GO012_RS14145	COG0444	Belongs to the ABC transporter superfamily
GO012_RS14150	COG4608	Belongs to the ABC transporter superfamily
GO012_RS14195	COG0583	DNA-binding transcription factor activity
GO012_RS14205	COG0402	S-adenosylhomocysteine deaminase activity
GO012_RS14235	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GO012_RS14240	COG0277	FAD linked oxidase domain protein
GO012_RS14265	COG0583	DNA-binding transcription factor activity
GO012_RS14275	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
GO012_RS14285	COG1250	3-hydroxyacyl-CoA dehydrogenase
GO012_RS14290	COG2610	gluconate transmembrane transporter activity
GO012_RS14295	COG1028	Short-chain dehydrogenase reductase Sdr
GO012_RS14345	COG4235	cytochrome complex assembly
GO012_RS14345	COG3088	subunit of a heme lyase
GO012_RS14350	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GO012_RS14355	COG1138	Cytochrome C-type biogenesis protein
GO012_RS14370	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
GO012_RS14375	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
GO012_RS14380	COG4133	protoheme IX ABC transporter activity
GO012_RS14410	COG3157	Type VI secretion system effector, Hcp
GO012_RS14415	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
GO012_RS14420	COG1518	maintenance of DNA repeat elements
GO012_RS14430	COG1857	crispr-associated protein
GO012_RS14460	COG1175	transmembrane transport
GO012_RS14465	COG1840	ABC-type Fe3 transport system, periplasmic component
GO012_RS14470	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
GO012_RS14475	COG3383	formate dehydrogenase (NAD+) activity
GO012_RS14480	COG1473	amidohydrolase
GO012_RS14495	COG2814	Major facilitator Superfamily
GO012_RS14510	COG1126	abc transporter atp-binding protein
GO012_RS14515	COG0765	amino acid transport
GO012_RS14535	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GO012_RS14540	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GO012_RS14545	COG1120	ATPase activity
GO012_RS14550	COG4774	siderophore transport
GO012_RS14555	COG1116	anion transmembrane transporter activity
GO012_RS14560	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GO012_RS14580	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GO012_RS14585	COG0583	DNA-binding transcription factor activity
GO012_RS14605	COG2814	Major facilitator Superfamily
GO012_RS14640	COG1414	Transcriptional regulator
GO012_RS14665	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
GO012_RS14670	COG2271	Major facilitator Superfamily
GO012_RS14680	COG1309	transcriptional regulator
GO012_RS14705	COG1376	ErfK ybiS ycfS ynhG family protein
GO012_RS14720	COG0719	Fe-S assembly protein
GO012_RS14725	COG0396	ATPase activity
GO012_RS14730	COG0719	Fe-S assembly protein
GO012_RS14735	COG0316	Belongs to the HesB IscA family
GO012_RS14750	COG1309	transcriptional regulator
GO012_RS14755	COG1304	FMN binding
GO012_RS14780	COG0583	DNA-binding transcription factor activity
GO012_RS14790	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GO012_RS14795	COG1120	ATPase activity
GO012_RS14820	COG2261	transglycosylase associated protein
GO012_RS14825	COG2050	protein possibly involved in aromatic compounds catabolism
GO012_RS14830	COG0277	FAD linked oxidase domain protein
GO012_RS14830	COG0247	lactate metabolic process
GO012_RS14835	COG0628	permease
GO012_RS14845	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
GO012_RS14845	COG0574	Belongs to the PEP-utilizing enzyme family
GO012_RS14855	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
GO012_RS14860	COG4256	Hemin uptake protein
GO012_RS14870	COG0791	NLP P60 protein
GO012_RS14880	COG0386	Belongs to the glutathione peroxidase family
GO012_RS14900	COG0583	DNA-binding transcription factor activity
GO012_RS14920	COG0072	phenylalanine-tRNA ligase activity
GO012_RS14920	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GO012_RS14960	COG3137	Salt-induced outer membrane protein
GO012_RS14965	COG1105	Belongs to the carbohydrate kinase PfkB family
GO012_RS14985	COG2350	Protein conserved in bacteria
GO012_RS14990	COG2353	YceI-like domain
GO012_RS15010	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GO012_RS15020	COG0444	Belongs to the ABC transporter superfamily
GO012_RS15025	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GO012_RS15030	COG0601	transmembrane transport
GO012_RS15035	COG4166	transmembrane transport
GO012_RS15040	COG2095	MarC family integral membrane protein
GO012_RS15045	COG1454	alcohol dehydrogenase
GO012_RS15045	COG1012	belongs to the aldehyde dehydrogenase family
GO012_RS15050	COG1435	thymidine kinase activity
GO012_RS15055	COG2916	Histone family protein nucleoid-structuring protein H-NS
GO012_RS15060	COG1210	Utp--glucose-1-phosphate uridylyltransferase
GO012_RS15065	COG0745	RESPONSE REGULATOR receiver
GO012_RS15070	COG1752	Esterase of the alpha-beta hydrolase superfamily
GO012_RS15080	COG0788	formyltetrahydrofolate deformylase activity
GO012_RS15115	COG1522	sequence-specific DNA binding
GO012_RS15125	COG2181	nitrate reductase activity
GO012_RS15130	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
GO012_RS15135	COG1140	nitrate reductase beta subunit
GO012_RS15140	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
GO012_RS15145	COG2223	nitrite transmembrane transporter activity
GO012_RS15150	COG3850	Histidine kinase
GO012_RS15155	COG2197	response regulator
GO012_RS15160	COG4932	domain protein
GO012_RS15165	COG0243	molybdopterin cofactor binding
GO012_RS15170	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
GO012_RS15170	COG2146	nitrite reductase [NAD(P)H] activity
GO012_RS15175	COG1116	anion transmembrane transporter activity
GO012_RS15185	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
GO012_RS15190	COG3707	response regulator
GO012_RS15195	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
GO012_RS15205	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
GO012_RS15210	COG4572	Cation transport regulator
GO012_RS15215	COG0387	Pfam Sodium calcium exchanger
GO012_RS15225	COG2912	Transglutaminase-like superfamily
GO012_RS15230	COG3094	Invasion gene expression up-regulator, SirB
GO012_RS15235	COG2890	protein-(glutamine-N5) methyltransferase activity
GO012_RS15260	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
GO012_RS15265	COG0659	secondary active sulfate transmembrane transporter activity
GO012_RS15285	COG0012	GTP binding
GO012_RS15350	COG1262	PFAM Formylglycine-generating sulfatase enzyme
GO012_RS15360	COG1262	PFAM Formylglycine-generating sulfatase enzyme
GO012_RS15375	COG3501	Rhs element vgr protein
GO012_RS15380	COG2885	chlorophyll binding
GO012_RS15400	COG3122	Protein conserved in bacteria
GO012_RS15415	COG0583	DNA-binding transcription factor activity
GO012_RS15445	COG0583	DNA-binding transcription factor activity
GO012_RS15450	COG0410	ABC transporter
GO012_RS15465	COG0559	Belongs to the binding-protein-dependent transport system permease family
GO012_RS15475	COG1882	Formate acetyltransferase
GO012_RS15490	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
GO012_RS15495	COG0583	DNA-binding transcription factor activity
GO012_RS15535	COG2308	Evidence 4 Homologs of previously reported genes of
GO012_RS15550	COG4774	siderophore transport
GO012_RS15560	COG1619	proteins homologs of microcin C7 resistance protein MccF
GO012_RS15580	COG2719	SpoVR family
GO012_RS15610	COG0179	Fumarylacetoacetate (FAA) hydrolase
GO012_RS15625	COG2894	cell division
GO012_RS15635	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
GO012_RS15640	COG0318	PFAM AMP-dependent synthetase and ligase
GO012_RS15645	COG3065	identical protein binding
GO012_RS15655	COG1199	ATP-dependent helicase activity
GO012_RS15660	COG0251	oxidation-reduction process
GO012_RS15680	COG1760	l-serine dehydratase
GO012_RS15685	COG2200	EAL domain
GO012_RS15690	COG1253	flavin adenine dinucleotide binding
GO012_RS15695	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
GO012_RS15695	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GO012_RS15700	COG3715	PTS system
GO012_RS15705	COG3716	PTS system mannose fructose sorbose family IID component
GO012_RS15720	COG2226	methyltransferase
GO012_RS15725	COG0768	penicillin binding
GO012_RS15730	COG1278	Cold shock
GO012_RS15755	COG1414	Transcriptional regulator
GO012_RS15760	COG2814	Major facilitator Superfamily
GO012_RS15780	COG1956	GAF domain-containing protein
GO012_RS15785	COG2995	paraquat-inducible protein a
GO012_RS15790	COG3008	intermembrane lipid transfer
GO012_RS15815	COG2990	Protein conserved in bacteria
GO012_RS15835	COG2372	response to copper ion
GO012_RS15845	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
GO012_RS15850	COG1770	oligopeptidase
GO012_RS15855	COG2979	Protein of unknown function (DUF533)
GO012_RS15860	COG3141	response to X-ray
GO012_RS15870	COG0800	Aldolase
GO012_RS15875	COG0129	dihydroxy-acid dehydratase activity
GO012_RS15880	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
GO012_RS15885	COG1737	Transcriptional regulator
GO012_RS15895	COG1560	Kdo2-lipid A biosynthetic process
GO012_RS15900	COG0739	heme binding
GO012_RS15905	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
GO012_RS15915	COG1108	ABC-type Mn2 Zn2 transport systems permease components
GO012_RS15940	COG0494	nUDIX hydrolase
GO012_RS15950	COG1335	isochorismatase
GO012_RS15955	COG1801	Protein of unknown function DUF72
GO012_RS15960	COG3788	relative of glutathione S-transferase, MAPEG superfamily
GO012_RS15980	COG3102	Protein conserved in bacteria
GO012_RS15990	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
GO012_RS16015	COG1172	Belongs to the binding-protein-dependent transport system permease family
GO012_RS16025	COG1879	ABC-type sugar transport system periplasmic component
GO012_RS16030	COG1528	Iron-storage protein
GO012_RS16035	COG2211	Major facilitator Superfamily
GO012_RS16045	COG0477	Major facilitator Superfamily
GO012_RS16060	COG1528	Iron-storage protein
GO012_RS16070	COG0814	amino acid
GO012_RS16075	COG3318	Belongs to the UPF0149 family
GO012_RS16075	COG3012	SEC-C Motif Domain Protein
GO012_RS16100	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
GO012_RS16110	COG2197	response regulator
GO012_RS16120	COG2197	response regulator
GO012_RS16145	COG0366	Alpha amylase catalytic
GO012_RS16175	COG2354	Protein conserved in bacteria
GO012_RS16180	COG0697	spore germination
GO012_RS16185	COG3727	T/G mismatch-specific endonuclease activity
GO012_RS16190	COG0270	DNA (cytosine-5-)-methyltransferase activity
GO012_RS16195	COG1418	mRNA catabolic process
GO012_RS16205	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
GO012_RS16225	COG0251	oxidation-reduction process
GO012_RS16240	COG1376	ErfK ybiS ycfS ynhG family protein
GO012_RS16260	COG0025	NhaP-type Na H and K H
GO012_RS16265	COG1309	transcriptional regulator
GO012_RS16270	COG0604	alcohol dehydrogenase
GO012_RS16290	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
GO012_RS16315	COG2264	protein methyltransferase activity
GO012_RS16335	COG2994	toxin metabolic process
GO012_RS16370	COG0582	viral genome integration into host DNA
GO012_RS16380	COG0534	Mate efflux family protein
GO012_RS16390	COG0582	viral genome integration into host DNA
GO012_RS16405	COG1108	ABC-type Mn2 Zn2 transport systems permease components
GO012_RS16410	COG0803	Belongs to the bacterial solute-binding protein 9 family
GO012_RS16440	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
GO012_RS16450	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
GO012_RS16455	COG0803	Belongs to the bacterial solute-binding protein 9 family
GO012_RS16460	COG1121	(ABC) transporter
GO012_RS16465	COG1108	ABC-type Mn2 Zn2 transport systems permease components
GO012_RS16470	COG1108	ABC-type Mn2 Zn2 transport systems permease components
GO012_RS16485	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
GO012_RS16495	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
GO012_RS16500	COG0523	cobalamin synthesis protein
GO012_RS16525	COG0523	cobalamin synthesis protein
GO012_RS16535	COG0735	belongs to the Fur family
GO012_RS16540	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GO012_RS16555	COG0582	viral genome integration into host DNA
GO012_RS16560	COG1169	isochorismate synthase
GO012_RS16565	COG2814	Major facilitator Superfamily
GO012_RS16570	COG1132	(ABC) transporter
GO012_RS16585	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GO012_RS16585	COG3433	isochorismatase activity
GO012_RS16585	COG2226	methyltransferase
GO012_RS16605	COG1021	2,3-dihydroxybenzoate-AMP ligase
GO012_RS16610	COG4771	TonB-dependent receptor
GO012_RS16690	COG3504	Conjugal transfer protein
GO012_RS16740	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
GO012_RS16765	COG0154	amidase activity
GO012_RS16795	COG1960	acyl-CoA dehydrogenase activity
GO012_RS16800	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GO012_RS16805	COG1250	3-hydroxyacyl-CoA dehydrogenase
GO012_RS16820	COG2197	response regulator
GO012_RS16855	COG3706	GGDEF domain
GO012_RS16880	COG3615	Tellurite resistance protein tehB
GO012_RS16885	COG5001	Diguanylate cyclase
GO012_RS16885	COG3300	MHYT domain
GO012_RS16895	COG0477	Major facilitator Superfamily
GO012_RS16905	COG0583	DNA-binding transcription factor activity
GO012_RS16910	COG1942	4-Oxalocrotonate Tautomerase
GO012_RS16920	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
GO012_RS16940	COG1289	transmembrane transporter activity
GO012_RS16950	COG3344	reverse transcriptase
GO012_RS16960	COG2925	Exonuclease
GO012_RS16965	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
GO012_RS16970	COG0640	Transcriptional regulator
GO012_RS16975	COG0531	amino acid
GO012_RS16985	COG0583	DNA-binding transcription factor activity
GO012_RS16990	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GO012_RS17020	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
GO012_RS17045	COG0463	Glycosyl transferase, family 2
GO012_RS17055	COG1442	glycosyl transferase family 8
GO012_RS17055	COG1216	Glycosyl transferase, family 2
GO012_RS17060	COG0438	transferase activity, transferring glycosyl groups
GO012_RS17125	COG0297	glycogen (starch) synthase activity
GO012_RS17130	COG1051	belongs to the nudix hydrolase family
GO012_RS17135	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GO012_RS17140	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
GO012_RS17145	COG0110	maltose O-acetyltransferase activity
GO012_RS17200	COG1253	flavin adenine dinucleotide binding
GO012_RS17205	COG2982	Protein involved in outer membrane biogenesis
GO012_RS17220	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
GO012_RS17225	COG0443	Heat shock 70 kDa protein
GO012_RS17230	COG5002	protein histidine kinase activity
GO012_RS17250	COG1301	dicarboxylic acid transport
GO012_RS17275	COG2205	protein histidine kinase activity
GO012_RS17280	COG0745	RESPONSE REGULATOR receiver
GO012_RS17295	COG4608	Belongs to the ABC transporter superfamily
GO012_RS17300	COG0444	Belongs to the ABC transporter superfamily
GO012_RS17310	COG0601	transmembrane transport
GO012_RS17315	COG0747	negative chemotaxis
GO012_RS17320	COG4948	Mandelate Racemase Muconate Lactonizing
GO012_RS17325	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GO012_RS17335	COG1070	Carbohydrate kinase
GO012_RS17370	COG1830	Aldolase
GO012_RS17375	COG0351	phosphomethylpyrimidine kinase
GO012_RS17410	COG2015	COG2015, Alkyl sulfatase and related hydrolases
GO012_RS17415	COG0583	DNA-binding transcription factor activity
GO012_RS17425	COG2252	PERMEase
GO012_RS17430	COG0583	DNA-binding transcription factor activity
GO012_RS17435	COG5455	response to cobalt ion
GO012_RS17455	COG4807	Protein conserved in bacteria
GO012_RS17465	COG3275	phosphorelay sensor kinase activity
GO012_RS17475	COG1174	glycine betaine transport
GO012_RS17480	COG1125	glycine betaine transport
GO012_RS17485	COG1174	glycine betaine transport
GO012_RS17490	COG1732	Glycine betaine
GO012_RS17495	COG1472	Belongs to the glycosyl hydrolase 3 family
GO012_RS17500	COG0277	FAD linked oxidase domain protein
GO012_RS17510	COG1686	Belongs to the peptidase S11 family
GO012_RS17520	COG0586	Pfam SNARE associated Golgi protein
GO012_RS17525	COG1538	Outer membrane efflux protein
GO012_RS17530	COG2723	6-phospho-beta-galactosidase activity
GO012_RS17545	COG3659	wide pore channel activity
GO012_RS17550	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
GO012_RS17560	COG1346	cytolysis
GO012_RS17570	COG2949	membrane
GO012_RS17580	COG1129	ABC transporter
GO012_RS17595	COG2311	Membrane
GO012_RS17610	COG4771	TonB-dependent receptor
GO012_RS17615	COG0833	amino acid
GO012_RS17620	COG0583	DNA-binding transcription factor activity
GO012_RS17625	COG2855	membrane
GO012_RS17635	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
GO012_RS17635	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GO012_RS17635	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GO012_RS17640	COG1105	Belongs to the carbohydrate kinase PfkB family
GO012_RS17645	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
GO012_RS17645	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
GO012_RS17650	COG2814	Major facilitator Superfamily
GO012_RS17665	COG1312	Catalyzes the dehydration of D-mannonate
GO012_RS17670	COG0246	Mannitol dehydrogenase
GO012_RS17675	COG0523	cobalamin synthesis protein
GO012_RS17680	COG0671	phosphoesterase, PA-phosphatase related
GO012_RS17685	COG0791	NLP P60 protein
GO012_RS17690	COG2200	EAL domain
GO012_RS17695	COG4166	transmembrane transport
GO012_RS17700	COG4174	ABC transporter (Permease)
GO012_RS17705	COG4239	(ABC) transporter, permease
GO012_RS17710	COG4172	Belongs to the ABC transporter superfamily
GO012_RS17720	COG2814	Major facilitator Superfamily
GO012_RS17725	COG1187	pseudouridine synthase activity
GO012_RS17730	COG1061	Type III restriction enzyme res subunit
GO012_RS17750	COG0494	nUDIX hydrolase
GO012_RS17755	COG1349	DNA-binding transcription factor activity
GO012_RS17780	COG0628	permease
GO012_RS17795	COG0659	secondary active sulfate transmembrane transporter activity
GO012_RS17800	COG2239	Acts as a magnesium transporter
GO012_RS17805	COG4615	Cyclic peptide transporter
GO012_RS17810	COG3145	DNA-N1-methyladenine dioxygenase activity
GO012_RS17815	COG2169	Transcriptional regulator
GO012_RS17815	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
GO012_RS17830	COG0642	Histidine kinase
GO012_RS17830	COG2198	Histidine kinase
GO012_RS17840	COG2205	protein histidine kinase activity
GO012_RS17840	COG0784	Response regulator, receiver
GO012_RS17865	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
GO012_RS17870	COG0584	glycerophosphoryl diester phosphodiesterase
GO012_RS17875	COG2271	Major facilitator Superfamily
GO012_RS17880	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
GO012_RS17890	COG0247	lactate metabolic process
GO012_RS17900	COG2271	Major facilitator Superfamily
GO012_RS17910	COG1414	Transcriptional regulator
GO012_RS17925	COG5464	transposase or invertase
GO012_RS17935	COG0318	PFAM AMP-dependent synthetase and ligase
GO012_RS17960	COG1169	isochorismate synthase
GO012_RS17965	COG2153	protein acetylation
GO012_RS17980	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GO012_RS17985	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
GO012_RS17995	COG0839	Belongs to the complex I subunit 6 family
GO012_RS18010	COG1034	ATP synthesis coupled electron transport
GO012_RS18020	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
GO012_RS18040	COG0583	DNA-binding transcription factor activity
GO012_RS18045	COG0436	Aminotransferase
GO012_RS18055	COG0471	metal ion transport
GO012_RS18055	COG0490	domain, Protein
GO012_RS18060	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GO012_RS18075	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
GO012_RS18080	COG0857	belongs to the CobB CobQ family
GO012_RS18080	COG0280	phosphate acetyltransferase
GO012_RS18085	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
GO012_RS18090	COG0622	Phosphoesterase
GO012_RS18095	COG0625	glutathione transferase activity
GO012_RS18100	COG0625	glutathione transferase activity
GO012_RS18105	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
GO012_RS18110	COG1090	epimerase
GO012_RS18120	COG4598	ABC transporter
GO012_RS18125	COG4160	amino acid transport
GO012_RS18130	COG4215	(ABC) transporter
GO012_RS18140	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GO012_RS18145	COG0163	prenyltransferase activity
GO012_RS18150	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
GO012_RS18155	COG1286	toxin biosynthetic process
GO012_RS18160	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
GO012_RS18165	COG0285	dihydrofolate synthase activity
GO012_RS18175	COG0586	Pfam SNARE associated Golgi protein
GO012_RS18185	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
GO012_RS18205	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GO012_RS18220	COG3101	peptidyl-lysine hydroxylation
GO012_RS18225	COG0730	response to heat
GO012_RS18240	COG2890	protein-(glutamine-N5) methyltransferase activity
GO012_RS18250	COG2062	phosphohistidine phosphatase, SixA
GO012_RS18265	COG3691	Protein conserved in bacteria
GO012_RS18275	COG2853	Lipoprotein
GO012_RS18280	COG2116	formate transmembrane transporter activity
GO012_RS18300	COG0583	DNA-binding transcription factor activity
GO012_RS18305	COG0590	tRNA wobble adenosine to inosine editing
GO012_RS18310	COG2807	transmembrane transport
GO012_RS18320	COG0436	Aminotransferase
GO012_RS18325	COG3275	phosphorelay sensor kinase activity
GO012_RS18330	COG3279	Response regulator of the LytR AlgR family
GO012_RS18345	COG3961	Belongs to the TPP enzyme family
GO012_RS18350	COG0667	Aldo Keto reductase
GO012_RS18365	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
GO012_RS18370	COG2200	EAL domain
GO012_RS18370	COG2199	diguanylate cyclase activity
GO012_RS18385	COG3415	Transposase
GO012_RS18390	COG3415	Transposase
GO012_RS18425	COG0583	DNA-binding transcription factor activity
GO012_RS18430	COG0385	Bile acid
GO012_RS18435	COG3530	Putative quorum-sensing-regulated virulence factor
GO012_RS18455	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
GO012_RS18470	COG2190	(PTS) system
GO012_RS18490	COG4319	ketosteroid isomerase
GO012_RS18500	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
GO012_RS18505	COG4208	sulfate ABC transporter
GO012_RS18510	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
GO012_RS18515	COG4150	thiosulfate binding
GO012_RS18525	COG2837	iron assimilation
GO012_RS18545	COG0860	N-Acetylmuramoyl-L-alanine amidase
GO012_RS18565	COG4816	utilization protein
GO012_RS18595	COG4820	ethanolamine utilization protein (EutJ)
GO012_RS18630	COG4917	ethanolamine utilization protein
GO012_RS18635	COG4810	utilization protein
GO012_RS18645	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
GO012_RS18650	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
GO012_RS18655	COG5342	invasion associated locus B
GO012_RS18665	COG0493	'glutamate synthase
GO012_RS18665	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
GO012_RS18670	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GO012_RS18680	COG1393	Belongs to the ArsC family
GO012_RS18695	COG0400	carboxylic ester hydrolase activity
GO012_RS18700	COG1444	tRNA N-acetyltransferase activity
GO012_RS18705	COG2321	neutral zinc metallopeptidase
GO012_RS18715	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
GO012_RS18725	COG2716	regulation of RNA biosynthetic process
GO012_RS18730	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
GO012_RS18735	COG0628	permease
GO012_RS18740	COG4783	chaperone-mediated protein folding
GO012_RS18745	COG1393	Belongs to the ArsC family
GO012_RS18760	COG2233	PERMEase
GO012_RS18770	COG2723	6-phospho-beta-galactosidase activity
GO012_RS18785	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
GO012_RS18795	COG0248	Ppx GppA phosphatase
GO012_RS18800	COG2200	EAL domain
GO012_RS18820	COG0641	radical SAM
GO012_RS18835	COG0516	GMP reductase activity
GO012_RS18835	COG0517	IMP dehydrogenase activity
GO012_RS18845	COG1645	bacterial-type flagellum-dependent swarming motility
GO012_RS18865	COG2976	Protein conserved in bacteria
GO012_RS18895	COG4953	penicillin-binding protein 1C
GO012_RS18900	COG2373	Large extracellular alpha-helical protein
GO012_RS18905	COG2897	thiosulfate sulfurtransferase activity
GO012_RS18925	COG2975	iron-sulfur cluster assembly
GO012_RS18930	COG0633	Ferredoxin
GO012_RS18950	COG0822	iron-sulfur transferase activity
GO012_RS18980	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
GO012_RS18985	COG3683	transport system, periplasmic component
GO012_RS18990	COG3711	transcriptional antiterminator
GO012_RS18995	COG2814	Major facilitator Superfamily
GO012_RS19000	COG2017	converts alpha-aldose to the beta-anomer
GO012_RS19005	COG0477	Major facilitator Superfamily
GO012_RS19005	COG2814	Major facilitator Superfamily
GO012_RS19010	COG0457	Tetratricopeptide repeat
GO012_RS19020	COG2259	Doxx family
GO012_RS19030	COG1017	nitric oxide dioxygenase activity
GO012_RS19030	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
GO012_RS19035	COG0347	Belongs to the P(II) protein family
GO012_RS19040	COG2204	response regulator
GO012_RS19045	COG3170	Tfp pilus assembly protein FimV
GO012_RS19050	COG2205	protein histidine kinase activity
GO012_RS19055	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
GO012_RS19055	COG0047	phosphoribosylformylglycinamidine synthase activity
GO012_RS19065	COG0590	tRNA wobble adenosine to inosine editing
GO012_RS19070	COG0560	Phosphoserine phosphatase
GO012_RS19075	COG1737	Transcriptional regulator
GO012_RS19080	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
GO012_RS19090	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
GO012_RS19110	COG0681	Belongs to the peptidase S26 family
GO012_RS19120	COG3086	response to oxidative stress
GO012_RS19125	COG3026	antisigma factor binding
GO012_RS19145	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
GO012_RS19155	COG0513	Belongs to the DEAD box helicase family
GO012_RS19170	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GO012_RS19175	COG3118	belongs to the thioredoxin family
GO012_RS19190	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GO012_RS19195	COG5544	Lipoprotein
GO012_RS19200	COG0477	Major facilitator Superfamily
GO012_RS19225	COG0542	response to heat
GO012_RS19235	COG0564	pseudouridine synthase activity
GO012_RS19240	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GO012_RS19245	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
GO012_RS19255	COG1605	Chorismate mutase
GO012_RS19255	COG0077	Prephenate dehydratase
GO012_RS19265	COG0287	Prephenate dehydrogenase
GO012_RS19265	COG1605	Chorismate mutase
GO012_RS19270	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
GO012_RS19280	COG2199	diguanylate cyclase activity
GO012_RS19285	COG2885	chlorophyll binding
GO012_RS19320	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
GO012_RS19325	COG4137	Cytochrome C assembly protein
GO012_RS19330	COG4536	flavin adenine dinucleotide binding
GO012_RS19345	COG0497	DNA recombination
GO012_RS19360	COG2867	negative regulation of translational initiation
GO012_RS19390	COG2207	Transcriptional regulator
GO012_RS19390	COG3708	Transcriptional regulator
GO012_RS19395	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GO012_RS19420	COG3622	Belongs to the hyi family
GO012_RS19425	COG0477	Major facilitator Superfamily
GO012_RS19430	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
GO012_RS19435	COG2271	Major facilitator Superfamily
GO012_RS19450	COG0431	NADPH-dependent FMN reductase
GO012_RS19500	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GO012_RS19530	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GO012_RS19540	COG0235	Class ii aldolase
GO012_RS19550	COG1028	Short-chain dehydrogenase reductase Sdr
GO012_RS19565	COG2197	response regulator
GO012_RS19580	COG3188	usher protein
GO012_RS19600	COG3121	Chaperone
GO012_RS19605	COG3539	Fimbrial protein
GO012_RS19610	COG1012	belongs to the aldehyde dehydrogenase family
GO012_RS19615	COG3284	Transcriptional regulator
GO012_RS19620	COG0583	DNA-binding transcription factor activity
GO012_RS19630	COG0640	Transcriptional regulator
GO012_RS19635	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GO012_RS19650	COG2916	Histone family protein nucleoid-structuring protein H-NS
GO012_RS19665	COG4575	ribosome binding
GO012_RS19670	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GO012_RS19675	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
GO012_RS19680	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
GO012_RS19690	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GO012_RS19705	COG4176	ABC-type proline glycine betaine transport system permease component
GO012_RS19715	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
GO012_RS19725	COG1846	Transcriptional regulator
GO012_RS19730	COG1566	PFAM secretion protein HlyD family protein
GO012_RS19735	COG2814	Major facilitator Superfamily
GO012_RS19740	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
GO012_RS19760	COG1238	metal cluster binding
GO012_RS19765	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GO012_RS19770	COG2823	Periplasmic or secreted lipoprotein
GO012_RS19820	COG1546	Belongs to the CinA family
GO012_RS19825	COG0803	Belongs to the bacterial solute-binding protein 9 family
GO012_RS19830	COG1108	ABC-type Mn2 Zn2 transport systems permease components
GO012_RS19835	COG1121	(ABC) transporter
GO012_RS19845	COG2951	lytic endotransglycosylase activity
GO012_RS19850	COG3730	PTS system glucitol sorbitol-specific
GO012_RS19855	COG3732	PTS system glucitol sorbitol-specific
GO012_RS19865	COG1028	Short-chain dehydrogenase reductase Sdr
GO012_RS19870	COG4578	phosphoenolpyruvate-dependent sugar phosphotransferase system
GO012_RS19875	COG1349	DNA-binding transcription factor activity
GO012_RS19900	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
GO012_RS19905	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
GO012_RS19910	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
GO012_RS19915	COG1609	Transcriptional regulator
GO012_RS19920	COG1263	PTS System
GO012_RS19920	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GO012_RS19925	COG2723	6-phospho-beta-galactosidase activity
GO012_RS19935	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
GO012_RS19945	COG3260	NADH ubiquinone oxidoreductase 20
GO012_RS19950	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GO012_RS19955	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
GO012_RS19955	COG3261	NADH dehydrogenase
GO012_RS19960	COG0650	Formate hydrogenlyase subunit 4
GO012_RS19965	COG0651	ATP synthesis coupled electron transport
GO012_RS19970	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
GO012_RS19985	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
GO012_RS19990	COG0298	carbon dioxide binding
GO012_RS19995	COG0409	Hydrogenase expression formation protein
GO012_RS20000	COG0309	Hydrogenase expression formation protein (HypE)
GO012_RS20010	COG2723	6-phospho-beta-galactosidase activity
GO012_RS20020	COG4580	involved in the transport of maltose and maltodextrins
GO012_RS20025	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GO012_RS20030	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GO012_RS20035	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GO012_RS20040	COG1447	Phosphotransferase system cellobiose-specific component IIA
GO012_RS20045	COG1940	carbohydrate kinase activity
GO012_RS20050	COG1609	Transcriptional regulator
GO012_RS20060	COG1121	(ABC) transporter
GO012_RS20065	COG1108	ABC-type Mn2 Zn2 transport systems permease components
GO012_RS20070	COG1108	ABC-type Mn2 Zn2 transport systems permease components
GO012_RS20085	COG0679	Auxin Efflux Carrier
GO012_RS20105	COG3720	iron ion transport
GO012_RS20110	COG4558	Periplasmic binding protein
GO012_RS20115	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GO012_RS20140	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
GO012_RS20145	COG0163	prenyltransferase activity
GO012_RS20170	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
GO012_RS20175	COG4942	peptidase
GO012_RS20175	COG1388	LysM domain
GO012_RS20235	COG2234	aminopeptidase activity
GO012_RS20255	COG0720	synthase
GO012_RS20260	COG0602	queuosine metabolic process
GO012_RS20280	COG3956	TIGRFAM MazG family protein
GO012_RS20285	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
GO012_RS20295	COG4999	Histidine kinase
GO012_RS20295	COG3850	Histidine kinase
GO012_RS20295	COG3437	response regulator, receiver
GO012_RS20295	COG2205	protein histidine kinase activity
GO012_RS20305	COG1929	Belongs to the glycerate kinase type-1 family
GO012_RS20310	COG4948	Mandelate Racemase Muconate Lactonizing
GO012_RS20315	COG4948	Mandelate Racemase Muconate Lactonizing
GO012_RS20320	COG2271	Major facilitator Superfamily
GO012_RS20325	COG0716	FMN binding
GO012_RS20330	COG0564	pseudouridine synthase activity
GO012_RS20335	COG3098	single-species biofilm formation
GO012_RS20350	COG1611	Belongs to the LOG family
GO012_RS20355	COG0814	amino acid
GO012_RS20360	COG1760	l-serine dehydratase
GO012_RS20365	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
GO012_RS20375	COG0477	Major facilitator Superfamily
GO012_RS20380	COG1464	Belongs to the NlpA lipoprotein family
GO012_RS20385	COG2011	ABC-type metal ion transport system permease component
GO012_RS20390	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
GO012_RS20405	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GO012_RS20420	COG1454	alcohol dehydrogenase
GO012_RS20425	COG0235	Class ii aldolase
GO012_RS20430	COG0738	Major facilitator superfamily
GO012_RS20450	COG1349	DNA-binding transcription factor activity
GO012_RS20460	COG2363	Small membrane protein
GO012_RS20465	COG0583	DNA-binding transcription factor activity
GO012_RS20475	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
GO012_RS20480	COG2166	iron-sulfur cluster assembly
GO012_RS20485	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
GO012_RS20490	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
GO012_RS20565	COG2875	Belongs to the precorrin methyltransferase family
GO012_RS20575	COG2241	protein methyltransferase activity
GO012_RS20610	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
GO012_RS20645	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
GO012_RS20680	COG1454	alcohol dehydrogenase
GO012_RS20680	COG1012	belongs to the aldehyde dehydrogenase family
GO012_RS20685	COG4656	Part of a membrane complex involved in electron transport
GO012_RS20695	COG4810	utilization protein
GO012_RS20715	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
GO012_RS20720	COG0860	N-Acetylmuramoyl-L-alanine amidase
GO012_RS20725	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
GO012_RS20725	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
GO012_RS20735	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
GO012_RS20740	COG1074	ATP-dependent DNA helicase activity
GO012_RS20745	COG1025	Belongs to the peptidase M16 family
GO012_RS20750	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
GO012_RS20755	COG4967	type IV pilus modification protein PilV
GO012_RS20765	COG4795	General secretion pathway protein
GO012_RS20770	COG2165	general secretion pathway protein
GO012_RS20800	COG0861	Integral membrane protein TerC family
GO012_RS20810	COG0667	Aldo Keto reductase
GO012_RS20825	COG1609	Transcriptional regulator
GO012_RS20835	COG2186	Transcriptional regulator
GO012_RS20840	COG2723	6-phospho-beta-galactosidase activity
GO012_RS20845	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GO012_RS20850	COG1609	Transcriptional regulator
GO012_RS20855	COG0019	diaminopimelate decarboxylase activity
GO012_RS20860	COG0583	DNA-binding transcription factor activity
GO012_RS20865	COG1794	racemase activity, acting on amino acids and derivatives
GO012_RS20870	COG1917	Cupin 2, conserved barrel domain protein
GO012_RS20875	COG1175	transmembrane transport
GO012_RS20880	COG0395	ABC-type sugar transport system, permease component
GO012_RS20885	COG3842	ATPase activity
GO012_RS20915	COG2814	Major facilitator Superfamily
GO012_RS20920	COG1028	Short-chain dehydrogenase reductase Sdr
GO012_RS20925	COG0823	Involved in the tonB-independent uptake of proteins
GO012_RS20930	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
GO012_RS20935	COG0183	Belongs to the thiolase family
GO012_RS20950	COG0814	amino acid
GO012_RS20955	COG0667	Aldo Keto reductase
GO012_RS21005	COG0697	spore germination
GO012_RS21010	COG1846	Transcriptional regulator
GO012_RS21015	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
GO012_RS21020	COG0582	viral genome integration into host DNA
GO012_RS21025	COG4974	Belongs to the 'phage' integrase family
GO012_RS21035	COG3539	Fimbrial protein
GO012_RS21040	COG3121	Chaperone
GO012_RS21045	COG3188	usher protein
GO012_RS21050	COG3539	Fimbrial protein
GO012_RS21055	COG3539	Fimbrial protein
GO012_RS21060	COG3539	Fimbrial protein
GO012_RS21070	COG2388	GCN5-related N-acetyl-transferase
GO012_RS21075	COG3592	Divergent 4Fe-4S mono-cluster
GO012_RS21090	COG1289	transmembrane transporter activity
GO012_RS21095	COG1538	Outer membrane efflux protein
GO012_RS21105	COG3104	oligopeptide transport
GO012_RS21110	COG1393	Belongs to the ArsC family
GO012_RS21115	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
GO012_RS21155	COG0667	Aldo Keto reductase
GO012_RS21170	COG2814	Major facilitator Superfamily
GO012_RS21180	COG4942	peptidase
GO012_RS21200	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
GO012_RS21210	COG4974	Belongs to the 'phage' integrase family
GO012_RS21215	COG0716	FMN binding
GO012_RS21225	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
GO012_RS21235	COG1272	protein, Hemolysin III
GO012_RS21245	COG1737	Transcriptional regulator
GO012_RS21250	COG2723	6-phospho-beta-galactosidase activity
GO012_RS21270	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GO012_RS21275	COG1028	Short-chain dehydrogenase reductase Sdr
GO012_RS21295	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GO012_RS21300	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GO012_RS21305	COG0006	proline dipeptidase activity
GO012_RS21325	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
GO012_RS21330	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GO012_RS21345	COG2968	Membrane
GO012_RS21355	COG0668	transmembrane transport
GO012_RS21360	COG0191	fructose-bisphosphate aldolase activity
GO012_RS21375	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
GO012_RS21380	COG0501	Belongs to the peptidase M48B family
GO012_RS21420	COG2814	Major facilitator Superfamily
GO012_RS21430	COG2356	endonuclease I
GO012_RS21435	COG1385	rRNA (uridine-N3-)-methyltransferase activity
GO012_RS21440	COG0189	ligase activity
GO012_RS21460	COG2805	Type II/IV secretion system protein
GO012_RS21465	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
GO012_RS21470	COG0762	integral membrane protein
GO012_RS21485	COG0635	Involved in the biosynthesis of porphyrin-containing compound
GO012_RS21500	COG4214	carbohydrate transport
GO012_RS21510	COG3171	Protein conserved in bacteria
GO012_RS21520	COG1194	a g-specific adenine glycosylase
GO012_RS21535	COG2211	Major facilitator Superfamily
GO012_RS21540	COG1982	Orn Lys Arg decarboxylase major
GO012_RS21545	COG1811	Na channel or pump
GO012_RS21590	COG0626	cystathionine gamma-synthase activity
GO012_RS21615	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GO012_RS21620	COG0754	glutathionylspermidine amidase activity
GO012_RS21630	COG0625	glutathione transferase activity
GO012_RS21655	COG2211	Major facilitator Superfamily
GO012_RS21660	COG0848	biopolymer transport protein
GO012_RS21665	COG0811	peptide transport
GO012_RS21670	COG0626	cystathionine gamma-synthase activity
GO012_RS21675	COG0586	Pfam SNARE associated Golgi protein
GO012_RS21680	COG2207	Transcriptional regulator
GO012_RS21685	COG1979	alcohol dehydrogenase
GO012_RS21690	COG0656	L-ascorbic acid biosynthetic process
GO012_RS21700	COG1032	radical SAM domain protein
GO012_RS21705	COG2132	Multicopper oxidase
GO012_RS21710	COG0204	Acyl-transferase
GO012_RS21715	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
GO012_RS21720	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
GO012_RS21725	COG3111	PFAM Bacterial OB fold (BOF) protein
GO012_RS21730	COG0745	RESPONSE REGULATOR receiver
GO012_RS21735	COG0642	Histidine kinase
GO012_RS21745	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
GO012_RS21750	COG0187	DNA topoisomerase II activity
GO012_RS21755	COG3150	esterase
GO012_RS21760	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
GO012_RS21765	COG3151	Protein conserved in bacteria
GO012_RS21770	COG0494	nUDIX hydrolase
GO012_RS21785	COG0754	glutathionylspermidine amidase activity
GO012_RS21790	COG3384	dioxygenase
GO012_RS21805	COG2960	long-chain fatty acid transporting porin activity
GO012_RS21825	COG3025	triphosphatase activity
GO012_RS21830	COG4991	sh3 domain protein
GO012_RS21845	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
GO012_RS21905	COG0358	DNA primase activity
GO012_RS21910	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
GO012_RS21935	COG2197	response regulator
GO012_RS21940	COG0784	Response regulator, receiver
GO012_RS21940	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GO012_RS21940	COG2198	Histidine kinase
GO012_RS21940	COG2205	protein histidine kinase activity
GO012_RS21950	COG3247	response to pH
GO012_RS22020	COG2376	Dihydroxyacetone kinase
GO012_RS22025	COG1461	Dihydroxyacetone kinase
GO012_RS22040	COG2375	cellular response to nickel ion
GO012_RS22045	COG1695	Transcriptional regulator
GO012_RS22095	COG0446	pyridine nucleotide-disulphide oxidoreductase
GO012_RS22095	COG1902	pentaerythritol trinitrate reductase activity
GO012_RS22115	COG1451	nucleotide metabolic process
GO012_RS22120	COG0673	inositol 2-dehydrogenase activity
GO012_RS22125	COG0861	Integral membrane protein TerC family
GO012_RS22140	COG2721	sulfolactate sulfo-lyase activity
GO012_RS22150	COG2271	Major facilitator Superfamily
GO012_RS22155	COG2186	Transcriptional regulator
GO012_RS22160	COG0586	Pfam SNARE associated Golgi protein
GO012_RS22170	COG1422	Protein of unknown function (DUF1090)
GO012_RS22175	COG4575	ribosome binding
GO012_RS22180	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
GO012_RS22190	COG2259	Doxx family
GO012_RS22195	COG0435	Glutathione S-transferase
GO012_RS22200	COG3152	Membrane
GO012_RS22205	COG0583	DNA-binding transcription factor activity
GO012_RS22210	COG1741	Belongs to the pirin family
GO012_RS22230	COG1929	Belongs to the glycerate kinase type-1 family
GO012_RS22235	COG2084	Dehydrogenase
GO012_RS22245	COG2271	Major facilitator Superfamily
GO012_RS22255	COG2721	sulfolactate sulfo-lyase activity
GO012_RS22260	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GO012_RS22265	COG1349	DNA-binding transcription factor activity
GO012_RS22275	COG1105	Belongs to the carbohydrate kinase PfkB family
GO012_RS22280	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GO012_RS22280	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GO012_RS22280	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GO012_RS22285	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
GO012_RS22285	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
GO012_RS22295	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GO012_RS22300	COG3414	Phosphotransferase system galactitol-specific IIB component
GO012_RS22305	COG3775	system Galactitol-specific IIC component
GO012_RS22310	COG1063	alcohol dehydrogenase
GO012_RS22325	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
GO012_RS22345	COG2823	Periplasmic or secreted lipoprotein
GO012_RS22350	COG0701	Predicted permease
GO012_RS22355	COG0702	epimerase
GO012_RS22360	COG0693	protein deglycase activity
GO012_RS22375	COG3153	acetyltransferase
GO012_RS22395	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GO012_RS22400	COG0814	amino acid
GO012_RS22445	COG0195	Participates in both transcription termination and antitermination
GO012_RS22485	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
GO012_RS22495	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
GO012_RS22500	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
GO012_RS22510	COG1534	Rna-binding protein
GO012_RS22515	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
GO012_RS22520	COG2027	D-alanyl-D-alanine carboxypeptidase
GO012_RS22530	COG0697	spore germination
GO012_RS22545	COG0142	geranyltranstransferase activity
GO012_RS22550	COG3423	Transcriptional regulator
GO012_RS22560	COG5007	Belongs to the BolA IbaG family
GO012_RS22565	COG3113	response to antibiotic
GO012_RS22570	COG2854	intermembrane phospholipid transfer
GO012_RS22575	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
GO012_RS22580	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
GO012_RS22585	COG1127	ABC transporter
GO012_RS22590	COG0530	calcium, potassium:sodium antiporter activity
GO012_RS22600	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
GO012_RS22605	COG3117	lipopolysaccharide transmembrane transporter activity
GO012_RS22610	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
GO012_RS22615	COG1137	ATPase activity
GO012_RS22620	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
GO012_RS22625	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
GO012_RS22630	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GO012_RS22640	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
GO012_RS22645	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GO012_RS22650	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
GO012_RS22655	COG5002	protein histidine kinase activity
GO012_RS22655	COG0784	Response regulator, receiver
GO012_RS22655	COG2198	Histidine kinase
GO012_RS22660	COG1312	Catalyzes the dehydration of D-mannonate
GO012_RS22665	COG1063	alcohol dehydrogenase
GO012_RS22670	COG2271	Major facilitator Superfamily
GO012_RS22675	COG1242	4 iron, 4 sulfur cluster binding
GO012_RS22680	COG0070	glutamate synthase
GO012_RS22680	COG0067	glutamate synthase
GO012_RS22680	COG0069	glutamate synthase activity
GO012_RS22685	COG0493	'glutamate synthase
GO012_RS22695	COG2969	positive regulation of protein catabolic process
GO012_RS22700	COG0625	glutathione transferase activity
GO012_RS22720	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
GO012_RS22725	COG3105	Protein conserved in bacteria
GO012_RS22730	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GO012_RS22735	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GO012_RS22765	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
GO012_RS22770	COG0471	metal ion transport
GO012_RS22805	COG2732	(Barnase) inhibitor
GO012_RS22810	COG1289	transmembrane transporter activity
GO012_RS22825	COG0583	DNA-binding transcription factor activity
GO012_RS22830	COG0312	modulator of DNA gyrase
GO012_RS22835	COG3164	Protein of unknown function
GO012_RS22840	COG1530	ribonuclease E activity
GO012_RS22850	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
GO012_RS22855	COG1792	Involved in formation and maintenance of cell shape
GO012_RS22860	COG1077	Cell shape determining protein MreB Mrl
GO012_RS22865	COG2199	diguanylate cyclase activity
GO012_RS22865	COG2200	EAL domain
GO012_RS22875	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
GO012_RS22890	COG0511	ligase activity, forming carbon-carbon bonds
GO012_RS22895	COG0439	Biotin carboxylase
GO012_RS22900	COG3924	membrane
GO012_RS22905	COG4145	pantothenate transmembrane transporter activity
GO012_RS22925	COG1309	transcriptional regulator
GO012_RS22930	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GO012_RS22935	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GO012_RS22970	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
GO012_RS22990	COG0551	DNA topoisomerase type I activity
GO012_RS23000	COG0758	DNA mediated transformation
GO012_RS23020	COG0569	domain protein
GO012_RS23030	COG3036	rescue of stalled ribosome
GO012_RS23035	COG0789	Transcriptional regulator
GO012_RS23050	COG0202	RNA polymerase activity
GO012_RS23075	COG0201	protein transport
GO012_RS23140	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
GO012_RS23145	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
GO012_RS23180	COG0051	transcription antitermination factor activity, RNA binding
GO012_RS23195	COG2906	2 iron, 2 sulfur cluster binding
GO012_RS23235	COG2964	Protein conserved in bacteria
GO012_RS23240	COG0545	Peptidyl-prolyl cis-trans isomerase
GO012_RS23250	COG1047	Peptidyl-prolyl cis-trans
GO012_RS23255	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
GO012_RS23270	COG0488	(ABC) transporter
GO012_RS23275	COG0429	hydrolase of the alpha beta-hydrolase fold
GO012_RS23285	COG3954	Phosphoribulokinase
GO012_RS23290	COG1765	OsmC-like protein
GO012_RS23300	COG1289	transmembrane transporter activity
GO012_RS23305	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
GO012_RS23330	COG0738	Major facilitator superfamily
GO012_RS23335	COG0402	S-adenosylhomocysteine deaminase activity
GO012_RS23340	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
GO012_RS23345	COG2146	nitrite reductase [NAD(P)H] activity
GO012_RS23365	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
GO012_RS23370	COG0338	D12 class N6 adenine-specific DNA methyltransferase
GO012_RS23375	COG3266	domain, Protein
GO012_RS23390	COG4796	Type ii and iii secretion system protein
GO012_RS23415	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
GO012_RS23420	COG0494	nUDIX hydrolase
GO012_RS23430	COG1011	Hydrolase
GO012_RS23435	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
GO012_RS23455	COG0745	RESPONSE REGULATOR receiver
GO012_RS23460	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
GO012_RS23465	COG2183	response to ionizing radiation
GO012_RS23470	COG1918	ferrous iron import across plasma membrane
GO012_RS23495	COG1040	competence protein
GO012_RS23505	COG2610	gluconate transmembrane transporter activity
GO012_RS23510	COG1640	4-alpha-glucanotransferase
GO012_RS23515	COG0058	SHG alpha-glucan phosphorylase activity
GO012_RS23525	COG1349	DNA-binding transcription factor activity
GO012_RS23540	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
GO012_RS23545	COG0058	SHG alpha-glucan phosphorylase activity
GO012_RS23570	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
GO012_RS23580	COG2610	gluconate transmembrane transporter activity
GO012_RS23585	COG3265	gluconokinase activity
GO012_RS23590	COG1609	Transcriptional regulator
GO012_RS23595	COG1741	Belongs to the pirin family
GO012_RS23600	COG0673	inositol 2-dehydrogenase activity
GO012_RS23610	COG1247	-acetyltransferase
GO012_RS23615	COG0405	Gamma-glutamyltransferase
GO012_RS23625	COG0584	glycerophosphoryl diester phosphodiesterase
GO012_RS23645	COG1653	transport
GO012_RS23660	COG0410	ABC transporter
GO012_RS23665	COG0411	ABC transporter
GO012_RS23675	COG0559	Belongs to the binding-protein-dependent transport system permease family
GO012_RS23680	COG0683	leucine binding
GO012_RS23695	COG0683	leucine binding
GO012_RS23705	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
GO012_RS23720	COG2177	Part of the ABC transporter FtsEX involved in
GO012_RS23725	COG2884	Cell division ATP-binding protein ftsE
GO012_RS23730	COG0552	protein localization to endoplasmic reticulum
GO012_RS23735	COG0742	ribosomal rna small subunit methyltransferase
GO012_RS23740	COG3776	membrane
GO012_RS23750	COG3714	YhhN family
GO012_RS23765	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
GO012_RS23775	COG0477	Major facilitator Superfamily
GO012_RS23780	COG0628	permease
GO012_RS23820	COG3479	Phenolic acid decarboxylase
GO012_RS23830	COG0747	negative chemotaxis
GO012_RS23835	COG0601	transmembrane transport
GO012_RS23840	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GO012_RS23850	COG1124	(ABC) transporter
GO012_RS23865	COG2239	Acts as a magnesium transporter
GO012_RS23870	COG2081	HI0933 family
GO012_RS23875	COG0306	phosphate transporter
GO012_RS23885	COG0589	response to stress
GO012_RS23905	COG0671	phosphoesterase, PA-phosphatase related
GO012_RS23910	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
GO012_RS23915	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GO012_RS23925	COG1454	alcohol dehydrogenase
GO012_RS23935	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GO012_RS23940	COG1028	Short-chain dehydrogenase reductase Sdr
GO012_RS23945	COG0583	DNA-binding transcription factor activity
GO012_RS23950	COG1295	ribonuclease BN
GO012_RS23955	COG0477	Major facilitator Superfamily
GO012_RS23960	COG2982	Protein involved in outer membrane biogenesis
GO012_RS23975	COG0612	Peptidase, M16
GO012_RS23985	COG2200	EAL domain
GO012_RS23985	COG2199	diguanylate cyclase activity
GO012_RS23990	COG3118	belongs to the thioredoxin family
GO012_RS23990	COG0457	Tetratricopeptide repeat
GO012_RS23995	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
GO012_RS24000	COG1215	transferase activity, transferring glycosyl groups
GO012_RS24030	COG2194	sulfuric ester hydrolase activity
GO012_RS24050	COG1215	transferase activity, transferring glycosyl groups
GO012_RS24060	COG2894	cell division
GO012_RS24070	COG4608	Belongs to the ABC transporter superfamily
GO012_RS24075	COG0444	Belongs to the ABC transporter superfamily
GO012_RS24080	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GO012_RS24085	COG0601	transmembrane transport
GO012_RS24090	COG0747	negative chemotaxis
GO012_RS24115	COG2223	nitrite transmembrane transporter activity
GO012_RS24120	COG5571	outer membrane autotransporter
GO012_RS24125	COG2818	Glycosylase
GO012_RS24130	COG0456	acetyltransferase
GO012_RS24135	COG0243	molybdopterin cofactor binding
GO012_RS24140	COG2885	chlorophyll binding
GO012_RS24145	COG1609	Transcriptional regulator
GO012_RS24155	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GO012_RS24175	COG2814	Major facilitator Superfamily
GO012_RS24180	COG2944	sequence-specific DNA binding
GO012_RS24185	COG1278	Cold shock
GO012_RS24215	COG3274	enterobacterial common antigen metabolic process
GO012_RS24220	COG4682	membrane
GO012_RS24225	COG4682	membrane
GO012_RS24240	COG4213	ABC transporter substrate-binding protein
GO012_RS24245	COG1129	ABC transporter
GO012_RS24250	COG4214	carbohydrate transport
GO012_RS24255	COG2207	Transcriptional regulator
GO012_RS24255	COG1609	Transcriptional regulator
GO012_RS24260	COG2992	FlgJ-related protein
GO012_RS24265	COG0366	Alpha amylase catalytic
GO012_RS24270	COG3977	Valine--pyruvate aminotransferase
GO012_RS24275	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
GO012_RS24280	COG1414	Transcriptional regulator
GO012_RS24285	COG3276	selenocysteine insertion sequence binding
GO012_RS24295	COG0625	glutathione transferase activity
GO012_RS24315	COG3722	fumarate hydratase activity
GO012_RS24335	COG2186	Transcriptional regulator
GO012_RS24345	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
GO012_RS24365	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
GO012_RS24370	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GO012_RS24380	COG4942	peptidase
GO012_RS24385	COG2861	carbohydrate metabolic process
GO012_RS24390	COG0463	Glycosyl transferase, family 2
GO012_RS24400	COG0156	8-amino-7-oxononanoate synthase activity
GO012_RS24415	COG0859	PFAM glycosyl transferase family 9
GO012_RS24440	COG0859	PFAM glycosyl transferase family 9
GO012_RS24450	COG0438	transferase activity, transferring glycosyl groups
GO012_RS24455	COG1216	Glycosyl transferase, family 2
GO012_RS24460	COG1519	Transferase
GO012_RS24495	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
GO012_RS24525	COG0842	Transport permease protein
GO012_RS24530	COG1131	(ABC) transporter
GO012_RS24545	COG1561	YicC-like family, N-terminal region
GO012_RS24550	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
GO012_RS24555	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
GO012_RS24555	COG2169	Transcriptional regulator
GO012_RS24565	COG2860	membrane
GO012_RS24585	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
GO012_RS24590	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GO012_RS24595	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
GO012_RS24600	COG1494	fructose-1,6-bisphosphatase
GO012_RS24610	COG3152	Membrane
GO012_RS24635	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
GO012_RS24655	COG0786	glutamate:sodium symporter activity
GO012_RS24660	COG2233	PERMEase
GO012_RS24665	COG2982	Protein involved in outer membrane biogenesis
GO012_RS24670	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GO012_RS24670	COG1263	PTS System
GO012_RS24675	COG1486	melibiose metabolic process
GO012_RS24685	COG1501	Belongs to the glycosyl hydrolase 31 family
GO012_RS24690	COG2211	Major facilitator Superfamily
GO012_RS24700	COG0582	viral genome integration into host DNA
GO012_RS24735	COG1064	alcohol dehydrogenase
GO012_RS24745	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
GO012_RS24760	COG1464	Belongs to the NlpA lipoprotein family
GO012_RS24785	COG0583	DNA-binding transcription factor activity
GO012_RS24810	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GO012_RS24815	COG1538	Outer membrane efflux protein
GO012_RS24820	COG2814	Major facilitator Superfamily
GO012_RS24830	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GO012_RS24830	COG1263	PTS System
GO012_RS24835	COG0697	spore germination
GO012_RS24850	COG2828	Protein conserved in bacteria
GO012_RS24855	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
GO012_RS24860	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
GO012_RS24865	COG0583	DNA-binding transcription factor activity
GO012_RS24870	COG3384	dioxygenase
GO012_RS24880	COG1609	Transcriptional regulator
GO012_RS24890	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GO012_RS24890	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GO012_RS24895	COG1447	Phosphotransferase system cellobiose-specific component IIA
GO012_RS24900	COG4580	involved in the transport of maltose and maltodextrins
GO012_RS24925	COG2188	Transcriptional regulator
GO012_RS24965	COG2271	Major facilitator Superfamily
GO012_RS24975	COG2197	response regulator
GO012_RS24980	COG0440	acetolactate synthase activity
GO012_RS24985	COG0028	Belongs to the TPP enzyme family
GO012_RS25010	COG2814	Major facilitator Superfamily
GO012_RS25015	COG0583	DNA-binding transcription factor activity
GO012_RS25020	COG2610	gluconate transmembrane transporter activity
GO012_RS25040	COG2149	membrane
GO012_RS25055	COG2188	Transcriptional regulator
GO012_RS25065	COG3645	SOS response
GO012_RS25080	COG5645	(Lipo)protein
GO012_RS25085	COG0823	Involved in the tonB-independent uptake of proteins
GO012_RS25090	COG2271	Major facilitator Superfamily
GO012_RS25100	COG0800	Aldolase
GO012_RS25105	COG3734	2-keto-3-deoxy-galactonokinase
GO012_RS25110	COG2186	Transcriptional regulator
GO012_RS25125	COG0561	phosphatase activity
GO012_RS25130	COG0187	DNA topoisomerase II activity
GO012_RS25160	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
GO012_RS25190	COG2091	lysine biosynthetic process via aminoadipic acid
GO012_RS25195	COG0431	NADPH-dependent FMN reductase
GO012_RS25200	COG2252	PERMEase
GO012_RS25205	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GO012_RS25210	COG0363	glucosamine-6-phosphate deaminase activity
GO012_RS25215	COG2382	esterase
GO012_RS25225	COG0704	Plays a role in the regulation of phosphate uptake
GO012_RS25230	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
GO012_RS25235	COG0581	inorganic phosphate transmembrane transporter activity
GO012_RS25240	COG0573	inorganic phosphate transmembrane transporter activity
GO012_RS25245	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
GO012_RS25300	COG3312	ion transport
GO012_RS25315	COG0500	methyltransferase
GO012_RS25330	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GO012_RS25340	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
GO012_RS25375	COG0500	methyltransferase
GO012_RS25390	COG2771	luxR family
GO012_RS25410	COG2382	esterase
GO012_RS25430	COG1475	DNA binding
GO012_RS25435	COG3969	phosphoadenosine phosphosulfate
GO012_RS25450	COG1595	DNA-templated transcription, initiation
GO012_RS25460	COG4772	TonB-dependent receptor
GO012_RS25465	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
GO012_RS25505	COG2916	Histone family protein nucleoid-structuring protein H-NS
GO012_RS25510	COG0656	L-ascorbic acid biosynthetic process
GO012_RS25555	COG4172	Belongs to the ABC transporter superfamily
GO012_RS25575	COG0735	belongs to the Fur family
GO012_RS25580	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
GO012_RS25585	COG0523	cobalamin synthesis protein
GO012_RS25610	COG0523	cobalamin synthesis protein
GO012_RS25615	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
GO012_RS25625	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
GO012_RS25650	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
GO012_RS25735	COG4680	protein conserved in bacteria
GO012_RS25740	COG5499	transcription regulator containing HTH domain
GO012_RS25795	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
GO012_RS25810	COG0789	Transcriptional regulator
GO012_RS25815	COG2205	protein histidine kinase activity
GO012_RS25820	COG0745	RESPONSE REGULATOR receiver
GO012_RS25825	COG1276	copper resistance
GO012_RS25830	COG2372	response to copper ion
GO012_RS25835	COG3667	copper resistance
GO012_RS25840	COG2132	Multicopper oxidase
GO012_RS25850	COG0739	heme binding
GO012_RS25880	COG5569	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GO012_RS25915	COG3706	GGDEF domain
GO012_RS26010	COG1192	Involved in chromosome partitioning
GO012_RS26015	COG1475	DNA binding
GO012_RS26035	COG3436	PFAM IS66 Orf2 family protein
GO012_RS26040	COG4372	Transposase
GO012_RS26130	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GO012_RS26155	COG2144	transferase activity, transferring acyl groups
GO012_RS26190	COG4316	Uncharacterized protein conserved in bacteria (DUF2251)
GO012_RS26210	COG4245	von Willebrand factor, type A
GO012_RS26215	COG4245	von Willebrand factor, type A
GO012_RS26225	COG4245	von Willebrand factor, type A
GO012_RS26245	COG1358	cellular component organization or biogenesis
GO012_RS26350	COG1522	sequence-specific DNA binding
GO012_RS26420	COG1956	GAF domain-containing protein
GO012_RS26520	COG0523	cobalamin synthesis protein