locus-tag	class	description
CLQ46_RS00020	COG2203	Gaf domain
CLQ46_RS00020	COG2199	diguanylate cyclase activity
CLQ46_RS00025	COG5001	Diguanylate cyclase
CLQ46_RS00025	COG1716	ATPase activity
CLQ46_RS00045	COG4943	cyclic-guanylate-specific phosphodiesterase activity
CLQ46_RS00055	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CLQ46_RS00105	COG5569	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CLQ46_RS00135	COG0739	heme binding
CLQ46_RS00145	COG2132	Multicopper oxidase
CLQ46_RS00150	COG3667	copper resistance
CLQ46_RS00155	COG2372	response to copper ion
CLQ46_RS00160	COG1276	copper resistance
CLQ46_RS00165	COG0745	RESPONSE REGULATOR receiver
CLQ46_RS00170	COG2205	protein histidine kinase activity
CLQ46_RS00190	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
CLQ46_RS00205	COG0431	NADPH-dependent FMN reductase
CLQ46_RS00235	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
CLQ46_RS00300	COG2801	Transposase and inactivated derivatives
CLQ46_RS00310	COG0501	Belongs to the peptidase M48B family
CLQ46_RS00330	COG0542	response to heat
CLQ46_RS00335	COG0071	Belongs to the small heat shock protein (HSP20) family
CLQ46_RS00445	COG1660	Displays ATPase and GTPase activities
CLQ46_RS00840	COG5499	transcription regulator containing HTH domain
CLQ46_RS00905	COG3344	reverse transcriptase
CLQ46_RS00975	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
CLQ46_RS00985	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CLQ46_RS01065	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CLQ46_RS01075	COG1702	phosphate starvation-inducible protein PhoH
CLQ46_RS01195	COG3941	tape measure
CLQ46_RS01285	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CLQ46_RS01290	COG1475	DNA binding
CLQ46_RS01295	COG1475	DNA binding
CLQ46_RS01435	COG0328	RNA-DNA hybrid ribonuclease activity
CLQ46_RS01470	COG0237	dephospho-CoA kinase activity
CLQ46_RS01485	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
CLQ46_RS01495	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CLQ46_RS01500	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CLQ46_RS01615	COG3064	Membrane
CLQ46_RS01895	COG1349	DNA-binding transcription factor activity
CLQ46_RS01905	COG2084	Dehydrogenase
CLQ46_RS01985	COG2135	peptidase activity
CLQ46_RS02145	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
CLQ46_RS02200	COG0187	DNA topoisomerase II activity
CLQ46_RS02205	COG0561	phosphatase activity
CLQ46_RS02220	COG2186	Transcriptional regulator
CLQ46_RS02225	COG3734	2-keto-3-deoxy-galactonokinase
CLQ46_RS02230	COG0800	Aldolase
CLQ46_RS02260	COG2271	Major facilitator Superfamily
CLQ46_RS02265	COG0823	Involved in the tonB-independent uptake of proteins
CLQ46_RS02270	COG5645	(Lipo)protein
CLQ46_RS02285	COG3645	SOS response
CLQ46_RS02295	COG2188	Transcriptional regulator
CLQ46_RS02310	COG2149	membrane
CLQ46_RS02330	COG2610	gluconate transmembrane transporter activity
CLQ46_RS02335	COG0583	DNA-binding transcription factor activity
CLQ46_RS02340	COG2814	Major facilitator Superfamily
CLQ46_RS02365	COG0028	Belongs to the TPP enzyme family
CLQ46_RS02370	COG0440	acetolactate synthase activity
CLQ46_RS02375	COG2197	response regulator
CLQ46_RS02385	COG2271	Major facilitator Superfamily
CLQ46_RS02430	COG2188	Transcriptional regulator
CLQ46_RS02460	COG4580	involved in the transport of maltose and maltodextrins
CLQ46_RS02465	COG1447	Phosphotransferase system cellobiose-specific component IIA
CLQ46_RS02470	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CLQ46_RS02470	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CLQ46_RS02480	COG1609	Transcriptional regulator
CLQ46_RS02490	COG3384	dioxygenase
CLQ46_RS02495	COG0583	DNA-binding transcription factor activity
CLQ46_RS02500	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
CLQ46_RS02505	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
CLQ46_RS02510	COG2828	Protein conserved in bacteria
CLQ46_RS02525	COG0697	spore germination
CLQ46_RS02530	COG1263	PTS System
CLQ46_RS02530	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CLQ46_RS02540	COG2814	Major facilitator Superfamily
CLQ46_RS02550	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CLQ46_RS02585	COG0583	DNA-binding transcription factor activity
CLQ46_RS02610	COG1464	Belongs to the NlpA lipoprotein family
CLQ46_RS02625	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
CLQ46_RS02635	COG1064	alcohol dehydrogenase
CLQ46_RS02670	COG2211	Major facilitator Superfamily
CLQ46_RS02675	COG1501	Belongs to the glycosyl hydrolase 31 family
CLQ46_RS02685	COG1486	melibiose metabolic process
CLQ46_RS02690	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CLQ46_RS02690	COG1263	PTS System
CLQ46_RS02695	COG2982	Protein involved in outer membrane biogenesis
CLQ46_RS02700	COG2233	PERMEase
CLQ46_RS02705	COG0786	glutamate:sodium symporter activity
CLQ46_RS02725	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
CLQ46_RS02750	COG3152	Membrane
CLQ46_RS02760	COG1494	fructose-1,6-bisphosphatase
CLQ46_RS02765	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CLQ46_RS02770	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CLQ46_RS02775	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CLQ46_RS02795	COG2860	membrane
CLQ46_RS02805	COG2169	Transcriptional regulator
CLQ46_RS02805	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CLQ46_RS02810	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
CLQ46_RS02815	COG1561	YicC-like family, N-terminal region
CLQ46_RS02825	COG3039	Transposase
CLQ46_RS02840	COG1131	(ABC) transporter
CLQ46_RS02845	COG0842	Transport permease protein
CLQ46_RS02870	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CLQ46_RS02905	COG1519	Transferase
CLQ46_RS02910	COG1216	Glycosyl transferase, family 2
CLQ46_RS02915	COG0438	transferase activity, transferring glycosyl groups
CLQ46_RS02925	COG0859	PFAM glycosyl transferase family 9
CLQ46_RS02950	COG0859	PFAM glycosyl transferase family 9
CLQ46_RS02965	COG0156	8-amino-7-oxononanoate synthase activity
CLQ46_RS02975	COG0463	Glycosyl transferase, family 2
CLQ46_RS02980	COG2861	carbohydrate metabolic process
CLQ46_RS02985	COG4942	peptidase
CLQ46_RS02995	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CLQ46_RS03000	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CLQ46_RS03020	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
CLQ46_RS03030	COG2186	Transcriptional regulator
CLQ46_RS03050	COG3722	fumarate hydratase activity
CLQ46_RS03070	COG1566	PFAM secretion protein HlyD family protein
CLQ46_RS03075	COG0625	glutathione transferase activity
CLQ46_RS03085	COG3276	selenocysteine insertion sequence binding
CLQ46_RS03090	COG1414	Transcriptional regulator
CLQ46_RS03095	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
CLQ46_RS03100	COG3977	Valine--pyruvate aminotransferase
CLQ46_RS03105	COG0366	Alpha amylase catalytic
CLQ46_RS03115	COG2992	FlgJ-related protein
CLQ46_RS03120	COG1609	Transcriptional regulator
CLQ46_RS03120	COG2207	Transcriptional regulator
CLQ46_RS03125	COG4214	carbohydrate transport
CLQ46_RS03135	COG4213	ABC transporter substrate-binding protein
CLQ46_RS03155	COG4682	membrane
CLQ46_RS03160	COG4682	membrane
CLQ46_RS03165	COG3274	enterobacterial common antigen metabolic process
CLQ46_RS03205	COG1278	Cold shock
CLQ46_RS03210	COG2944	sequence-specific DNA binding
CLQ46_RS03215	COG2814	Major facilitator Superfamily
CLQ46_RS03240	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CLQ46_RS03250	COG1609	Transcriptional regulator
CLQ46_RS03255	COG2885	chlorophyll binding
CLQ46_RS03260	COG0243	molybdopterin cofactor binding
CLQ46_RS03265	COG0456	acetyltransferase
CLQ46_RS03270	COG2818	Glycosylase
CLQ46_RS03275	COG5571	outer membrane autotransporter
CLQ46_RS03280	COG2223	nitrite transmembrane transporter activity
CLQ46_RS03320	COG0747	negative chemotaxis
CLQ46_RS03325	COG0601	transmembrane transport
CLQ46_RS03330	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CLQ46_RS03335	COG0444	Belongs to the ABC transporter superfamily
CLQ46_RS03340	COG4608	Belongs to the ABC transporter superfamily
CLQ46_RS03365	COG1215	transferase activity, transferring glycosyl groups
CLQ46_RS03370	COG0457	Tetratricopeptide repeat
CLQ46_RS03385	COG2194	sulfuric ester hydrolase activity
CLQ46_RS03415	COG1215	transferase activity, transferring glycosyl groups
CLQ46_RS03420	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
CLQ46_RS03425	COG0457	Tetratricopeptide repeat
CLQ46_RS03425	COG3118	belongs to the thioredoxin family
CLQ46_RS03430	COG2199	diguanylate cyclase activity
CLQ46_RS03430	COG2200	EAL domain
CLQ46_RS03445	COG0612	Peptidase, M16
CLQ46_RS03460	COG2982	Protein involved in outer membrane biogenesis
CLQ46_RS03465	COG0477	Major facilitator Superfamily
CLQ46_RS03470	COG1295	ribonuclease BN
CLQ46_RS03475	COG0583	DNA-binding transcription factor activity
CLQ46_RS03480	COG1028	Short-chain dehydrogenase reductase Sdr
CLQ46_RS03485	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CLQ46_RS03495	COG1454	alcohol dehydrogenase
CLQ46_RS03505	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CLQ46_RS03510	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
CLQ46_RS03515	COG0671	phosphoesterase, PA-phosphatase related
CLQ46_RS03535	COG0589	response to stress
CLQ46_RS03545	COG0306	phosphate transporter
CLQ46_RS03550	COG2081	HI0933 family
CLQ46_RS03555	COG2239	Acts as a magnesium transporter
CLQ46_RS03565	COG1124	(ABC) transporter
CLQ46_RS03575	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CLQ46_RS03580	COG0601	transmembrane transport
CLQ46_RS03585	COG0747	negative chemotaxis
CLQ46_RS03600	COG3479	Phenolic acid decarboxylase
CLQ46_RS03640	COG0628	permease
CLQ46_RS03645	COG0477	Major facilitator Superfamily
CLQ46_RS03655	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
CLQ46_RS03670	COG3714	YhhN family
CLQ46_RS03680	COG3776	membrane
CLQ46_RS03685	COG0742	ribosomal rna small subunit methyltransferase
CLQ46_RS03690	COG0552	protein localization to endoplasmic reticulum
CLQ46_RS03695	COG2884	Cell division ATP-binding protein ftsE
CLQ46_RS03700	COG2177	Part of the ABC transporter FtsEX involved in
CLQ46_RS03715	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CLQ46_RS03725	COG0683	leucine binding
CLQ46_RS03740	COG0683	leucine binding
CLQ46_RS03745	COG0559	Belongs to the binding-protein-dependent transport system permease family
CLQ46_RS03795	COG0584	glycerophosphoryl diester phosphodiesterase
CLQ46_RS03805	COG0405	Gamma-glutamyltransferase
CLQ46_RS03810	COG1247	-acetyltransferase
CLQ46_RS03820	COG0673	inositol 2-dehydrogenase activity
CLQ46_RS03825	COG1741	Belongs to the pirin family
CLQ46_RS03830	COG1609	Transcriptional regulator
CLQ46_RS03835	COG3265	gluconokinase activity
CLQ46_RS03840	COG2610	gluconate transmembrane transporter activity
CLQ46_RS03850	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CLQ46_RS03875	COG0058	SHG alpha-glucan phosphorylase activity
CLQ46_RS03890	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
CLQ46_RS03905	COG1349	DNA-binding transcription factor activity
CLQ46_RS03920	COG0058	SHG alpha-glucan phosphorylase activity
CLQ46_RS03925	COG1640	4-alpha-glucanotransferase
CLQ46_RS03930	COG2610	gluconate transmembrane transporter activity
CLQ46_RS03940	COG1040	competence protein
CLQ46_RS03965	COG1918	ferrous iron import across plasma membrane
CLQ46_RS03970	COG2183	response to ionizing radiation
CLQ46_RS03975	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CLQ46_RS04000	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
CLQ46_RS04005	COG1011	Hydrolase
CLQ46_RS04015	COG0494	nUDIX hydrolase
CLQ46_RS04020	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
CLQ46_RS04045	COG4796	Type ii and iii secretion system protein
CLQ46_RS04065	COG3266	domain, Protein
CLQ46_RS04070	COG0338	D12 class N6 adenine-specific DNA methyltransferase
CLQ46_RS04075	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CLQ46_RS04100	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CLQ46_RS04105	COG0402	S-adenosylhomocysteine deaminase activity
CLQ46_RS04110	COG0738	Major facilitator superfamily
CLQ46_RS04135	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CLQ46_RS04140	COG1289	transmembrane transporter activity
CLQ46_RS04155	COG1765	OsmC-like protein
CLQ46_RS04160	COG3954	Phosphoribulokinase
CLQ46_RS04170	COG0429	hydrolase of the alpha beta-hydrolase fold
CLQ46_RS04180	COG0488	(ABC) transporter
CLQ46_RS04200	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
CLQ46_RS04205	COG1047	Peptidyl-prolyl cis-trans
CLQ46_RS04215	COG0545	Peptidyl-prolyl cis-trans isomerase
CLQ46_RS04220	COG2964	Protein conserved in bacteria
CLQ46_RS04280	COG0051	transcription antitermination factor activity, RNA binding
CLQ46_RS04305	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
CLQ46_RS04320	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
CLQ46_RS04385	COG0201	protein transport
CLQ46_RS04410	COG0202	RNA polymerase activity
CLQ46_RS04425	COG0789	Transcriptional regulator
CLQ46_RS04430	COG3036	rescue of stalled ribosome
CLQ46_RS04460	COG0758	DNA mediated transformation
CLQ46_RS04470	COG0551	DNA topoisomerase type I activity
CLQ46_RS04490	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
CLQ46_RS04530	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CLQ46_RS04535	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CLQ46_RS04540	COG1309	transcriptional regulator
CLQ46_RS04545	COG0582	viral genome integration into host DNA
CLQ46_RS04560	COG3561	AntA/AntB antirepressor
CLQ46_RS04650	COG1802	Transcriptional regulator
CLQ46_RS04650	COG4626	Terminase
CLQ46_RS04680	COG4145	pantothenate transmembrane transporter activity
CLQ46_RS04685	COG3924	membrane
CLQ46_RS04690	COG0439	Biotin carboxylase
CLQ46_RS04695	COG0511	ligase activity, forming carbon-carbon bonds
CLQ46_RS04725	COG2199	diguanylate cyclase activity
CLQ46_RS04725	COG2200	EAL domain
CLQ46_RS04735	COG1077	Cell shape determining protein MreB Mrl
CLQ46_RS04740	COG1792	Involved in formation and maintenance of cell shape
CLQ46_RS04745	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
CLQ46_RS04755	COG1530	ribonuclease E activity
CLQ46_RS04760	COG3164	Protein of unknown function
CLQ46_RS04765	COG0312	modulator of DNA gyrase
CLQ46_RS04770	COG0583	DNA-binding transcription factor activity
CLQ46_RS04785	COG1289	transmembrane transporter activity
CLQ46_RS04790	COG2732	(Barnase) inhibitor
CLQ46_RS04815	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CLQ46_RS04820	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CLQ46_RS04825	COG3105	Protein conserved in bacteria
CLQ46_RS04830	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
CLQ46_RS04850	COG0625	glutathione transferase activity
CLQ46_RS04855	COG2969	positive regulation of protein catabolic process
CLQ46_RS04865	COG0493	'glutamate synthase
CLQ46_RS04870	COG0069	glutamate synthase activity
CLQ46_RS04870	COG0070	glutamate synthase
CLQ46_RS04870	COG0067	glutamate synthase
CLQ46_RS04880	COG1242	4 iron, 4 sulfur cluster binding
CLQ46_RS04885	COG2271	Major facilitator Superfamily
CLQ46_RS04890	COG1063	alcohol dehydrogenase
CLQ46_RS04895	COG1312	Catalyzes the dehydration of D-mannonate
CLQ46_RS04900	COG0784	Response regulator, receiver
CLQ46_RS04900	COG5002	protein histidine kinase activity
CLQ46_RS04900	COG2198	Histidine kinase
CLQ46_RS04905	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
CLQ46_RS04910	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CLQ46_RS04915	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CLQ46_RS04925	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CLQ46_RS04930	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
CLQ46_RS04935	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
CLQ46_RS04940	COG1137	ATPase activity
CLQ46_RS04945	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
CLQ46_RS04950	COG3117	lipopolysaccharide transmembrane transporter activity
CLQ46_RS04955	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
CLQ46_RS04965	COG0530	calcium, potassium:sodium antiporter activity
CLQ46_RS04975	COG1127	ABC transporter
CLQ46_RS04980	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
CLQ46_RS04985	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
CLQ46_RS04990	COG2854	intermembrane phospholipid transfer
CLQ46_RS04995	COG3113	response to antibiotic
CLQ46_RS05000	COG5007	Belongs to the BolA IbaG family
CLQ46_RS05010	COG3423	Transcriptional regulator
CLQ46_RS05015	COG0142	geranyltranstransferase activity
CLQ46_RS05030	COG0697	spore germination
CLQ46_RS05040	COG2027	D-alanyl-D-alanine carboxypeptidase
CLQ46_RS05050	COG1534	Rna-binding protein
CLQ46_RS05060	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CLQ46_RS05065	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
CLQ46_RS05075	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CLQ46_RS05115	COG0195	Participates in both transcription termination and antitermination
CLQ46_RS05165	COG0814	amino acid
CLQ46_RS05170	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CLQ46_RS05175	COG0826	peptidase U32
CLQ46_RS05180	COG0826	peptidase U32
CLQ46_RS05185	COG3154	lipid carrier protein
CLQ46_RS05190	COG3153	acetyltransferase
CLQ46_RS05205	COG0693	protein deglycase activity
CLQ46_RS05210	COG0702	epimerase
CLQ46_RS05215	COG0701	Predicted permease
CLQ46_RS05220	COG2823	Periplasmic or secreted lipoprotein
CLQ46_RS05240	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
CLQ46_RS05255	COG1063	alcohol dehydrogenase
CLQ46_RS05260	COG3775	system Galactitol-specific IIC component
CLQ46_RS05265	COG3414	Phosphotransferase system galactitol-specific IIB component
CLQ46_RS05270	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CLQ46_RS05280	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CLQ46_RS05280	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
CLQ46_RS05285	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CLQ46_RS05285	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CLQ46_RS05285	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CLQ46_RS05290	COG1105	Belongs to the carbohydrate kinase PfkB family
CLQ46_RS05300	COG1349	DNA-binding transcription factor activity
CLQ46_RS05305	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CLQ46_RS05310	COG2721	sulfolactate sulfo-lyase activity
CLQ46_RS05315	COG2271	Major facilitator Superfamily
CLQ46_RS05325	COG2084	Dehydrogenase
CLQ46_RS05330	COG1929	Belongs to the glycerate kinase type-1 family
CLQ46_RS05350	COG1741	Belongs to the pirin family
CLQ46_RS05355	COG0583	DNA-binding transcription factor activity
CLQ46_RS05360	COG3152	Membrane
CLQ46_RS05365	COG0435	Glutathione S-transferase
CLQ46_RS05370	COG2259	Doxx family
CLQ46_RS05380	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
CLQ46_RS05385	COG4575	ribosome binding
CLQ46_RS05390	COG1422	Protein of unknown function (DUF1090)
CLQ46_RS05400	COG0586	Pfam SNARE associated Golgi protein
CLQ46_RS05405	COG2186	Transcriptional regulator
CLQ46_RS05410	COG2271	Major facilitator Superfamily
CLQ46_RS05420	COG2721	sulfolactate sulfo-lyase activity
CLQ46_RS05435	COG0861	Integral membrane protein TerC family
CLQ46_RS05440	COG0673	inositol 2-dehydrogenase activity
CLQ46_RS05445	COG1451	nucleotide metabolic process
CLQ46_RS05465	COG1902	pentaerythritol trinitrate reductase activity
CLQ46_RS05465	COG0446	pyridine nucleotide-disulphide oxidoreductase
CLQ46_RS05520	COG1695	Transcriptional regulator
CLQ46_RS05525	COG2375	cellular response to nickel ion
CLQ46_RS05540	COG1461	Dihydroxyacetone kinase
CLQ46_RS05545	COG2376	Dihydroxyacetone kinase
CLQ46_RS05625	COG3247	response to pH
CLQ46_RS05635	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CLQ46_RS05635	COG2198	Histidine kinase
CLQ46_RS05635	COG2205	protein histidine kinase activity
CLQ46_RS05635	COG0784	Response regulator, receiver
CLQ46_RS05640	COG2197	response regulator
CLQ46_RS05665	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CLQ46_RS05670	COG0358	DNA primase activity
CLQ46_RS05675	COG0828	Belongs to the bacterial ribosomal protein bS21 family
CLQ46_RS05745	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
CLQ46_RS05760	COG4991	sh3 domain protein
CLQ46_RS05765	COG3025	triphosphatase activity
CLQ46_RS05785	COG2960	long-chain fatty acid transporting porin activity
CLQ46_RS05800	COG3384	dioxygenase
CLQ46_RS05805	COG0754	glutathionylspermidine amidase activity
CLQ46_RS05820	COG0494	nUDIX hydrolase
CLQ46_RS05825	COG3151	Protein conserved in bacteria
CLQ46_RS05830	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
CLQ46_RS05835	COG3150	esterase
CLQ46_RS05845	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
CLQ46_RS05850	COG2249	NAD(P)H dehydrogenase (quinone) activity
CLQ46_RS05855	COG0642	Histidine kinase
CLQ46_RS05865	COG3111	PFAM Bacterial OB fold (BOF) protein
CLQ46_RS05870	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
CLQ46_RS05875	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CLQ46_RS05880	COG0204	Acyl-transferase
CLQ46_RS05885	COG2132	Multicopper oxidase
CLQ46_RS05890	COG1032	radical SAM domain protein
CLQ46_RS05900	COG0656	L-ascorbic acid biosynthetic process
CLQ46_RS05905	COG1979	alcohol dehydrogenase
CLQ46_RS05910	COG2207	Transcriptional regulator
CLQ46_RS05915	COG0586	Pfam SNARE associated Golgi protein
CLQ46_RS05920	COG0626	cystathionine gamma-synthase activity
CLQ46_RS05935	COG0848	biopolymer transport protein
CLQ46_RS05940	COG2211	Major facilitator Superfamily
CLQ46_RS05965	COG0625	glutathione transferase activity
CLQ46_RS05975	COG0754	glutathionylspermidine amidase activity
CLQ46_RS05980	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CLQ46_RS06000	COG0583	DNA-binding transcription factor activity
CLQ46_RS06005	COG0626	cystathionine gamma-synthase activity
CLQ46_RS06270	COG3423	Transcriptional regulator
CLQ46_RS06280	COG1278	Cold shock
CLQ46_RS06285	COG3423	Transcriptional regulator
CLQ46_RS06360	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
CLQ46_RS06370	COG1811	Na channel or pump
CLQ46_RS06380	COG1982	Orn Lys Arg decarboxylase major
CLQ46_RS06385	COG2211	Major facilitator Superfamily
CLQ46_RS06400	COG1194	a g-specific adenine glycosylase
CLQ46_RS06410	COG3171	Protein conserved in bacteria
CLQ46_RS06420	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CLQ46_RS06435	COG0762	integral membrane protein
CLQ46_RS06440	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
CLQ46_RS06445	COG2805	Type II/IV secretion system protein
CLQ46_RS06465	COG0189	ligase activity
CLQ46_RS06470	COG1385	rRNA (uridine-N3-)-methyltransferase activity
CLQ46_RS06475	COG2356	endonuclease I
CLQ46_RS06485	COG2814	Major facilitator Superfamily
CLQ46_RS06525	COG2146	nitrite reductase [NAD(P)H] activity
CLQ46_RS06540	COG1028	Short-chain dehydrogenase reductase Sdr
CLQ46_RS06545	COG1414	Transcriptional regulator
CLQ46_RS06575	COG1028	Short-chain dehydrogenase reductase Sdr
CLQ46_RS06580	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
CLQ46_RS06610	COG0501	Belongs to the peptidase M48B family
CLQ46_RS06615	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CLQ46_RS06630	COG0191	fructose-bisphosphate aldolase activity
CLQ46_RS06635	COG0668	transmembrane transport
CLQ46_RS06645	COG2968	Membrane
CLQ46_RS06660	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CLQ46_RS06665	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
CLQ46_RS06685	COG0006	proline dipeptidase activity
CLQ46_RS06690	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CLQ46_RS06695	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CLQ46_RS06715	COG1028	Short-chain dehydrogenase reductase Sdr
CLQ46_RS06720	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CLQ46_RS06740	COG2723	6-phospho-beta-galactosidase activity
CLQ46_RS06745	COG1737	Transcriptional regulator
CLQ46_RS06755	COG1272	protein, Hemolysin III
CLQ46_RS06765	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
CLQ46_RS06775	COG0716	FMN binding
CLQ46_RS06780	COG4974	Belongs to the 'phage' integrase family
CLQ46_RS06790	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
CLQ46_RS06815	COG4942	peptidase
CLQ46_RS06825	COG2814	Major facilitator Superfamily
CLQ46_RS06840	COG0667	Aldo Keto reductase
CLQ46_RS06875	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
CLQ46_RS06880	COG1393	Belongs to the ArsC family
CLQ46_RS06895	COG1538	Outer membrane efflux protein
CLQ46_RS06900	COG1289	transmembrane transporter activity
CLQ46_RS06915	COG3592	Divergent 4Fe-4S mono-cluster
CLQ46_RS06920	COG2388	GCN5-related N-acetyl-transferase
CLQ46_RS06930	COG3539	Fimbrial protein
CLQ46_RS06935	COG3539	Fimbrial protein
CLQ46_RS06940	COG3539	Fimbrial protein
CLQ46_RS06945	COG3188	usher protein
CLQ46_RS06950	COG3121	Chaperone
CLQ46_RS06955	COG3539	Fimbrial protein
CLQ46_RS06965	COG4974	Belongs to the 'phage' integrase family
CLQ46_RS06970	COG0582	viral genome integration into host DNA
CLQ46_RS06980	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
CLQ46_RS06985	COG1846	Transcriptional regulator
CLQ46_RS06990	COG0697	spore germination
CLQ46_RS07040	COG0667	Aldo Keto reductase
CLQ46_RS07045	COG0814	amino acid
CLQ46_RS07060	COG0183	Belongs to the thiolase family
CLQ46_RS07070	COG0823	Involved in the tonB-independent uptake of proteins
CLQ46_RS07075	COG1028	Short-chain dehydrogenase reductase Sdr
CLQ46_RS07080	COG2814	Major facilitator Superfamily
CLQ46_RS07110	COG3842	ATPase activity
CLQ46_RS07115	COG0395	ABC-type sugar transport system, permease component
CLQ46_RS07120	COG1175	transmembrane transport
CLQ46_RS07125	COG1917	Cupin 2, conserved barrel domain protein
CLQ46_RS07130	COG1794	racemase activity, acting on amino acids and derivatives
CLQ46_RS07135	COG0583	DNA-binding transcription factor activity
CLQ46_RS07145	COG1609	Transcriptional regulator
CLQ46_RS07150	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CLQ46_RS07155	COG2723	6-phospho-beta-galactosidase activity
CLQ46_RS07160	COG2186	Transcriptional regulator
CLQ46_RS07170	COG1609	Transcriptional regulator
CLQ46_RS07195	COG0667	Aldo Keto reductase
CLQ46_RS07205	COG0861	Integral membrane protein TerC family
CLQ46_RS07235	COG2165	general secretion pathway protein
CLQ46_RS07240	COG4795	General secretion pathway protein
CLQ46_RS07250	COG4967	type IV pilus modification protein PilV
CLQ46_RS07255	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
CLQ46_RS07260	COG1025	Belongs to the peptidase M16 family
CLQ46_RS07265	COG1074	ATP-dependent DNA helicase activity
CLQ46_RS07270	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CLQ46_RS07280	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
CLQ46_RS07280	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
CLQ46_RS07285	COG0860	N-Acetylmuramoyl-L-alanine amidase
CLQ46_RS07290	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CLQ46_RS07320	COG4656	Part of a membrane complex involved in electron transport
CLQ46_RS07325	COG1012	belongs to the aldehyde dehydrogenase family
CLQ46_RS07325	COG1454	alcohol dehydrogenase
CLQ46_RS07355	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
CLQ46_RS07520	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
CLQ46_RS07525	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
CLQ46_RS07530	COG2166	iron-sulfur cluster assembly
CLQ46_RS07535	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CLQ46_RS07545	COG0583	DNA-binding transcription factor activity
CLQ46_RS07550	COG2363	Small membrane protein
CLQ46_RS07560	COG1349	DNA-binding transcription factor activity
CLQ46_RS07580	COG0738	Major facilitator superfamily
CLQ46_RS07585	COG0235	Class ii aldolase
CLQ46_RS07590	COG1454	alcohol dehydrogenase
CLQ46_RS07605	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CLQ46_RS07620	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CLQ46_RS07625	COG2011	ABC-type metal ion transport system permease component
CLQ46_RS07630	COG1464	Belongs to the NlpA lipoprotein family
CLQ46_RS07640	COG0477	Major facilitator Superfamily
CLQ46_RS07650	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CLQ46_RS07655	COG1760	l-serine dehydratase
CLQ46_RS07660	COG0814	amino acid
CLQ46_RS07665	COG1611	Belongs to the LOG family
CLQ46_RS07680	COG3098	single-species biofilm formation
CLQ46_RS07685	COG0564	pseudouridine synthase activity
CLQ46_RS07690	COG0716	FMN binding
CLQ46_RS07695	COG2271	Major facilitator Superfamily
CLQ46_RS07700	COG4948	Mandelate Racemase Muconate Lactonizing
CLQ46_RS07705	COG4948	Mandelate Racemase Muconate Lactonizing
CLQ46_RS07710	COG1929	Belongs to the glycerate kinase type-1 family
CLQ46_RS07715	COG3437	response regulator, receiver
CLQ46_RS07715	COG3850	Histidine kinase
CLQ46_RS07715	COG2205	protein histidine kinase activity
CLQ46_RS07715	COG4999	Histidine kinase
CLQ46_RS07725	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CLQ46_RS07730	COG3956	TIGRFAM MazG family protein
CLQ46_RS07750	COG0602	queuosine metabolic process
CLQ46_RS07755	COG0720	synthase
CLQ46_RS07775	COG2234	aminopeptidase activity
CLQ46_RS07835	COG1388	LysM domain
CLQ46_RS07835	COG4942	peptidase
CLQ46_RS07840	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CLQ46_RS07865	COG0163	prenyltransferase activity
CLQ46_RS07870	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
CLQ46_RS07915	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CLQ46_RS07920	COG4558	Periplasmic binding protein
CLQ46_RS07925	COG3720	iron ion transport
CLQ46_RS07945	COG0679	Auxin Efflux Carrier
CLQ46_RS07960	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CLQ46_RS07965	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CLQ46_RS07970	COG1121	(ABC) transporter
CLQ46_RS07975	COG0803	Belongs to the bacterial solute-binding protein 9 family
CLQ46_RS07980	COG1609	Transcriptional regulator
CLQ46_RS07985	COG1940	carbohydrate kinase activity
CLQ46_RS07990	COG1447	Phosphotransferase system cellobiose-specific component IIA
CLQ46_RS07995	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CLQ46_RS08000	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CLQ46_RS08005	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CLQ46_RS08015	COG4580	involved in the transport of maltose and maltodextrins
CLQ46_RS08025	COG2723	6-phospho-beta-galactosidase activity
CLQ46_RS08035	COG0309	Hydrogenase expression formation protein (HypE)
CLQ46_RS08040	COG0409	Hydrogenase expression formation protein
CLQ46_RS08045	COG0298	carbon dioxide binding
CLQ46_RS08050	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
CLQ46_RS08070	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
CLQ46_RS08075	COG0651	ATP synthesis coupled electron transport
CLQ46_RS08080	COG0650	Formate hydrogenlyase subunit 4
CLQ46_RS08085	COG3261	NADH dehydrogenase
CLQ46_RS08085	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
CLQ46_RS08090	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CLQ46_RS08095	COG3260	NADH ubiquinone oxidoreductase 20
CLQ46_RS08105	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
CLQ46_RS08115	COG2723	6-phospho-beta-galactosidase activity
CLQ46_RS08120	COG1263	PTS System
CLQ46_RS08120	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CLQ46_RS08125	COG1609	Transcriptional regulator
CLQ46_RS08130	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
CLQ46_RS08135	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
CLQ46_RS08140	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
CLQ46_RS08170	COG1349	DNA-binding transcription factor activity
CLQ46_RS08175	COG4578	phosphoenolpyruvate-dependent sugar phosphotransferase system
CLQ46_RS08180	COG1028	Short-chain dehydrogenase reductase Sdr
CLQ46_RS08190	COG3732	PTS system glucitol sorbitol-specific
CLQ46_RS08195	COG3730	PTS system glucitol sorbitol-specific
CLQ46_RS08200	COG2951	lytic endotransglycosylase activity
CLQ46_RS08210	COG1121	(ABC) transporter
CLQ46_RS08215	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CLQ46_RS08220	COG0803	Belongs to the bacterial solute-binding protein 9 family
CLQ46_RS08225	COG1546	Belongs to the CinA family
CLQ46_RS08250	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
CLQ46_RS08280	COG2823	Periplasmic or secreted lipoprotein
CLQ46_RS08285	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CLQ46_RS08290	COG1238	metal cluster binding
CLQ46_RS08310	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CLQ46_RS08315	COG2814	Major facilitator Superfamily
CLQ46_RS08320	COG1566	PFAM secretion protein HlyD family protein
CLQ46_RS08325	COG1846	Transcriptional regulator
CLQ46_RS08335	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
CLQ46_RS08345	COG4176	ABC-type proline glycine betaine transport system permease component
CLQ46_RS08360	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CLQ46_RS08370	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CLQ46_RS08375	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CLQ46_RS08380	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CLQ46_RS08385	COG4575	ribosome binding
CLQ46_RS08425	COG2916	Histone family protein nucleoid-structuring protein H-NS
CLQ46_RS08440	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CLQ46_RS08445	COG0640	Transcriptional regulator
CLQ46_RS08455	COG0583	DNA-binding transcription factor activity
CLQ46_RS08460	COG3284	Transcriptional regulator
CLQ46_RS08470	COG3539	Fimbrial protein
CLQ46_RS08475	COG3121	Chaperone
CLQ46_RS08495	COG3188	usher protein
CLQ46_RS08505	COG3539	Fimbrial protein
CLQ46_RS08510	COG2197	response regulator
CLQ46_RS08525	COG1028	Short-chain dehydrogenase reductase Sdr
CLQ46_RS08535	COG0235	Class ii aldolase
CLQ46_RS08550	COG4974	Belongs to the 'phage' integrase family
CLQ46_RS08585	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
CLQ46_RS08605	COG3344	reverse transcriptase
CLQ46_RS08640	COG4695	Portal protein
CLQ46_RS08820	COG2867	negative regulation of translational initiation
CLQ46_RS08835	COG0497	DNA recombination
CLQ46_RS08855	COG4536	flavin adenine dinucleotide binding
CLQ46_RS08860	COG4137	Cytochrome C assembly protein
CLQ46_RS08865	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CLQ46_RS08900	COG2885	chlorophyll binding
CLQ46_RS08905	COG2199	diguanylate cyclase activity
CLQ46_RS08915	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CLQ46_RS08920	COG0287	Prephenate dehydrogenase
CLQ46_RS08920	COG1605	Chorismate mutase
CLQ46_RS08930	COG1605	Chorismate mutase
CLQ46_RS08930	COG0077	Prephenate dehydratase
CLQ46_RS08940	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
CLQ46_RS08945	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CLQ46_RS08960	COG0542	response to heat
CLQ46_RS08985	COG0477	Major facilitator Superfamily
CLQ46_RS08990	COG5544	Lipoprotein
CLQ46_RS08995	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CLQ46_RS09005	COG3148	PFAM DTW domain containing protein
CLQ46_RS09010	COG3118	belongs to the thioredoxin family
CLQ46_RS09015	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CLQ46_RS09030	COG0513	Belongs to the DEAD box helicase family
CLQ46_RS09040	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
CLQ46_RS09050	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
CLQ46_RS09055	COG3026	antisigma factor binding
CLQ46_RS09060	COG3086	response to oxidative stress
CLQ46_RS09070	COG0681	Belongs to the peptidase S26 family
CLQ46_RS09090	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
CLQ46_RS09100	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
CLQ46_RS09105	COG1737	Transcriptional regulator
CLQ46_RS09110	COG0560	Phosphoserine phosphatase
CLQ46_RS09125	COG0047	phosphoribosylformylglycinamidine synthase activity
CLQ46_RS09125	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CLQ46_RS09130	COG2205	protein histidine kinase activity
CLQ46_RS09135	COG3170	Tfp pilus assembly protein FimV
CLQ46_RS09140	COG2204	response regulator
CLQ46_RS09145	COG0347	Belongs to the P(II) protein family
CLQ46_RS09150	COG1017	nitric oxide dioxygenase activity
CLQ46_RS09150	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CLQ46_RS09165	COG2259	Doxx family
CLQ46_RS09170	COG1940	carbohydrate kinase activity
CLQ46_RS09175	COG0457	Tetratricopeptide repeat
CLQ46_RS09180	COG0477	Major facilitator Superfamily
CLQ46_RS09180	COG2814	Major facilitator Superfamily
CLQ46_RS09185	COG2017	converts alpha-aldose to the beta-anomer
CLQ46_RS09190	COG2814	Major facilitator Superfamily
CLQ46_RS09195	COG3711	transcriptional antiterminator
CLQ46_RS09200	COG3683	transport system, periplasmic component
CLQ46_RS09205	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
CLQ46_RS09235	COG0822	iron-sulfur transferase activity
CLQ46_RS09255	COG0633	Ferredoxin
CLQ46_RS09260	COG2975	iron-sulfur cluster assembly
CLQ46_RS09280	COG2897	thiosulfate sulfurtransferase activity
CLQ46_RS09285	COG2373	Large extracellular alpha-helical protein
CLQ46_RS09290	COG4953	penicillin-binding protein 1C
CLQ46_RS09325	COG2976	Protein conserved in bacteria
CLQ46_RS09345	COG1645	bacterial-type flagellum-dependent swarming motility
CLQ46_RS09355	COG0516	GMP reductase activity
CLQ46_RS09355	COG0517	IMP dehydrogenase activity
CLQ46_RS09405	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CLQ46_RS09485	COG3344	reverse transcriptase
CLQ46_RS09500	COG5484	DNA packaging
CLQ46_RS09500	COG3728	DNA packaging
CLQ46_RS09630	COG3039	Transposase
CLQ46_RS09670	COG3179	chitinase
CLQ46_RS09680	COG3119	arylsulfatase activity
CLQ46_RS09705	COG2200	EAL domain
CLQ46_RS09720	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
CLQ46_RS09735	COG2723	6-phospho-beta-galactosidase activity
CLQ46_RS09745	COG2233	PERMEase
CLQ46_RS09760	COG1393	Belongs to the ArsC family
CLQ46_RS09765	COG4783	chaperone-mediated protein folding
CLQ46_RS09770	COG0628	permease
CLQ46_RS09775	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CLQ46_RS09780	COG2716	regulation of RNA biosynthetic process
CLQ46_RS09790	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
CLQ46_RS09800	COG2321	neutral zinc metallopeptidase
CLQ46_RS09805	COG1444	tRNA N-acetyltransferase activity
CLQ46_RS09810	COG0400	carboxylic ester hydrolase activity
CLQ46_RS09825	COG1393	Belongs to the ArsC family
CLQ46_RS09835	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CLQ46_RS09845	COG0493	'glutamate synthase
CLQ46_RS09845	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
CLQ46_RS09855	COG5342	invasion associated locus B
CLQ46_RS09860	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CLQ46_RS09865	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CLQ46_RS09875	COG4810	utilization protein
CLQ46_RS09965	COG0860	N-Acetylmuramoyl-L-alanine amidase
CLQ46_RS09985	COG2837	iron assimilation
CLQ46_RS09995	COG4150	thiosulfate binding
CLQ46_RS10000	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
CLQ46_RS10005	COG4208	sulfate ABC transporter
CLQ46_RS10010	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
CLQ46_RS10020	COG4319	ketosteroid isomerase
CLQ46_RS10055	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CLQ46_RS10075	COG3530	Putative quorum-sensing-regulated virulence factor
CLQ46_RS10080	COG0385	Bile acid
CLQ46_RS10085	COG0583	DNA-binding transcription factor activity
CLQ46_RS10120	COG3415	Transposase
CLQ46_RS10125	COG3415	Transposase
CLQ46_RS10140	COG2200	EAL domain
CLQ46_RS10140	COG2199	diguanylate cyclase activity
CLQ46_RS10145	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CLQ46_RS10160	COG0667	Aldo Keto reductase
CLQ46_RS10165	COG3961	Belongs to the TPP enzyme family
CLQ46_RS10180	COG3279	Response regulator of the LytR AlgR family
CLQ46_RS10185	COG3275	phosphorelay sensor kinase activity
CLQ46_RS10195	COG0436	Aminotransferase
CLQ46_RS10205	COG2807	transmembrane transport
CLQ46_RS10210	COG0590	tRNA wobble adenosine to inosine editing
CLQ46_RS10215	COG0583	DNA-binding transcription factor activity
CLQ46_RS10235	COG2116	formate transmembrane transporter activity
CLQ46_RS10240	COG2853	Lipoprotein
CLQ46_RS10255	COG3691	Protein conserved in bacteria
CLQ46_RS10270	COG2062	phosphohistidine phosphatase, SixA
CLQ46_RS10295	COG0730	response to heat
CLQ46_RS10300	COG3101	peptidyl-lysine hydroxylation
CLQ46_RS10315	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CLQ46_RS10335	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CLQ46_RS10345	COG0586	Pfam SNARE associated Golgi protein
CLQ46_RS10355	COG0285	dihydrofolate synthase activity
CLQ46_RS10360	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
CLQ46_RS10365	COG1286	toxin biosynthetic process
CLQ46_RS10370	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
CLQ46_RS10375	COG0163	prenyltransferase activity
CLQ46_RS10395	COG4160	amino acid transport
CLQ46_RS10400	COG4598	ABC transporter
CLQ46_RS10410	COG1090	epimerase
CLQ46_RS10415	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
CLQ46_RS10420	COG0625	glutathione transferase activity
CLQ46_RS10425	COG0625	glutathione transferase activity
CLQ46_RS10430	COG0622	Phosphoesterase
CLQ46_RS10435	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
CLQ46_RS10440	COG0280	phosphate acetyltransferase
CLQ46_RS10440	COG0857	belongs to the CobB CobQ family
CLQ46_RS10460	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CLQ46_RS10465	COG0490	domain, Protein
CLQ46_RS10465	COG0471	metal ion transport
CLQ46_RS10475	COG0436	Aminotransferase
CLQ46_RS10480	COG0583	DNA-binding transcription factor activity
CLQ46_RS10535	COG0839	Belongs to the complex I subunit 6 family
CLQ46_RS10545	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CLQ46_RS10550	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CLQ46_RS10565	COG2153	protein acetylation
CLQ46_RS10570	COG1169	isochorismate synthase
CLQ46_RS10595	COG0318	PFAM AMP-dependent synthetase and ligase
CLQ46_RS10605	COG5464	transposase or invertase
CLQ46_RS10620	COG1414	Transcriptional regulator
CLQ46_RS10630	COG2271	Major facilitator Superfamily
CLQ46_RS10640	COG0247	lactate metabolic process
CLQ46_RS10650	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
CLQ46_RS10655	COG2271	Major facilitator Superfamily
CLQ46_RS10660	COG0584	glycerophosphoryl diester phosphodiesterase
CLQ46_RS10670	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CLQ46_RS10700	COG2205	protein histidine kinase activity
CLQ46_RS10700	COG0784	Response regulator, receiver
CLQ46_RS10710	COG0642	Histidine kinase
CLQ46_RS10710	COG2198	Histidine kinase
CLQ46_RS10725	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CLQ46_RS10725	COG2169	Transcriptional regulator
CLQ46_RS10730	COG3145	DNA-N1-methyladenine dioxygenase activity
CLQ46_RS10735	COG4615	Cyclic peptide transporter
CLQ46_RS10740	COG2239	Acts as a magnesium transporter
CLQ46_RS10745	COG0659	secondary active sulfate transmembrane transporter activity
CLQ46_RS10760	COG0628	permease
CLQ46_RS10785	COG1349	DNA-binding transcription factor activity
CLQ46_RS10790	COG0494	nUDIX hydrolase
CLQ46_RS10810	COG1061	Type III restriction enzyme res subunit
CLQ46_RS10815	COG1187	pseudouridine synthase activity
CLQ46_RS10820	COG2814	Major facilitator Superfamily
CLQ46_RS10830	COG4172	Belongs to the ABC transporter superfamily
CLQ46_RS10835	COG4239	(ABC) transporter, permease
CLQ46_RS10840	COG4174	ABC transporter (Permease)
CLQ46_RS10845	COG4166	transmembrane transport
CLQ46_RS10850	COG2200	EAL domain
CLQ46_RS10855	COG0791	NLP P60 protein
CLQ46_RS10860	COG0671	phosphoesterase, PA-phosphatase related
CLQ46_RS10865	COG0523	cobalamin synthesis protein
CLQ46_RS10870	COG0246	Mannitol dehydrogenase
CLQ46_RS10875	COG1312	Catalyzes the dehydration of D-mannonate
CLQ46_RS10905	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
CLQ46_RS10905	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CLQ46_RS10910	COG1105	Belongs to the carbohydrate kinase PfkB family
CLQ46_RS10915	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CLQ46_RS10915	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CLQ46_RS10915	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
CLQ46_RS10925	COG2855	membrane
CLQ46_RS10935	COG0583	DNA-binding transcription factor activity
CLQ46_RS10940	COG0833	amino acid
CLQ46_RS10955	COG4771	TonB-dependent receptor
CLQ46_RS10970	COG2311	Membrane
CLQ46_RS10985	COG1129	ABC transporter
CLQ46_RS10995	COG2949	membrane
CLQ46_RS11010	COG1346	cytolysis
CLQ46_RS11020	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CLQ46_RS11025	COG3659	wide pore channel activity
CLQ46_RS11040	COG2723	6-phospho-beta-galactosidase activity
CLQ46_RS11045	COG1538	Outer membrane efflux protein
CLQ46_RS11050	COG0586	Pfam SNARE associated Golgi protein
CLQ46_RS11060	COG1686	Belongs to the peptidase S11 family
CLQ46_RS11070	COG0277	FAD linked oxidase domain protein
CLQ46_RS11075	COG1472	Belongs to the glycosyl hydrolase 3 family
CLQ46_RS11080	COG1732	Glycine betaine
CLQ46_RS11085	COG1174	glycine betaine transport
CLQ46_RS11090	COG1125	glycine betaine transport
CLQ46_RS11095	COG1174	glycine betaine transport
CLQ46_RS11105	COG3275	phosphorelay sensor kinase activity
CLQ46_RS11115	COG4807	Protein conserved in bacteria
CLQ46_RS11135	COG5455	response to cobalt ion
CLQ46_RS11140	COG0583	DNA-binding transcription factor activity
CLQ46_RS11145	COG2252	PERMEase
CLQ46_RS11155	COG0583	DNA-binding transcription factor activity
CLQ46_RS11170	COG0351	phosphomethylpyrimidine kinase
CLQ46_RS11175	COG1830	Aldolase
CLQ46_RS11210	COG1070	Carbohydrate kinase
CLQ46_RS11220	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CLQ46_RS11225	COG4948	Mandelate Racemase Muconate Lactonizing
CLQ46_RS11230	COG0747	negative chemotaxis
CLQ46_RS11235	COG0601	transmembrane transport
CLQ46_RS11240	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CLQ46_RS11245	COG0444	Belongs to the ABC transporter superfamily
CLQ46_RS11250	COG4608	Belongs to the ABC transporter superfamily
CLQ46_RS11260	COG0826	peptidase U32
CLQ46_RS11265	COG0745	RESPONSE REGULATOR receiver
CLQ46_RS11270	COG2205	protein histidine kinase activity
CLQ46_RS11295	COG1301	dicarboxylic acid transport
CLQ46_RS11310	COG5002	protein histidine kinase activity
CLQ46_RS11315	COG0443	Heat shock 70 kDa protein
CLQ46_RS11325	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
CLQ46_RS11340	COG2982	Protein involved in outer membrane biogenesis
CLQ46_RS11345	COG1253	flavin adenine dinucleotide binding
CLQ46_RS11395	COG0463	Glycosyl transferase, family 2
CLQ46_RS11410	COG2244	polysaccharide biosynthetic process
CLQ46_RS11420	COG1088	dTDP-glucose 4,6-dehydratase activity
CLQ46_RS11455	COG1088	dTDP-glucose 4,6-dehydratase activity
CLQ46_RS11520	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
CLQ46_RS11550	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CLQ46_RS11555	COG0583	DNA-binding transcription factor activity
CLQ46_RS11565	COG0531	amino acid
CLQ46_RS11570	COG0640	Transcriptional regulator
CLQ46_RS11575	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CLQ46_RS11580	COG2925	Exonuclease
CLQ46_RS11595	COG3344	reverse transcriptase
CLQ46_RS11605	COG1289	transmembrane transporter activity
CLQ46_RS11625	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
CLQ46_RS11635	COG1942	4-Oxalocrotonate Tautomerase
CLQ46_RS11640	COG0583	DNA-binding transcription factor activity
CLQ46_RS11645	COG0095	Lipoate-protein ligase
CLQ46_RS11650	COG0477	Major facilitator Superfamily
CLQ46_RS11665	COG3300	MHYT domain
CLQ46_RS11665	COG5001	Diguanylate cyclase
CLQ46_RS11675	COG3615	Tellurite resistance protein tehB
CLQ46_RS11700	COG3706	GGDEF domain
CLQ46_RS11765	COG2003	Belongs to the UPF0758 family
CLQ46_RS11820	COG3504	Conjugal transfer protein
CLQ46_RS11885	COG4771	TonB-dependent receptor
CLQ46_RS11890	COG1021	2,3-dihydroxybenzoate-AMP ligase
CLQ46_RS11910	COG2226	methyltransferase
CLQ46_RS11910	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CLQ46_RS11910	COG3433	isochorismatase activity
CLQ46_RS11925	COG1132	(ABC) transporter
CLQ46_RS11930	COG2814	Major facilitator Superfamily
CLQ46_RS11935	COG1169	isochorismate synthase
CLQ46_RS11940	COG0582	viral genome integration into host DNA
CLQ46_RS11950	COG0534	Mate efflux family protein
CLQ46_RS11960	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CLQ46_RS11980	COG0604	alcohol dehydrogenase
CLQ46_RS11985	COG1309	transcriptional regulator
CLQ46_RS11990	COG0025	NhaP-type Na H and K H
CLQ46_RS12035	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CLQ46_RS12045	COG1418	mRNA catabolic process
CLQ46_RS12050	COG0270	DNA (cytosine-5-)-methyltransferase activity
CLQ46_RS12055	COG3727	T/G mismatch-specific endonuclease activity
CLQ46_RS12060	COG0697	spore germination
CLQ46_RS12065	COG2354	Protein conserved in bacteria
CLQ46_RS12095	COG0366	Alpha amylase catalytic
CLQ46_RS12100	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CLQ46_RS12110	COG0765	amino acid transport
CLQ46_RS12115	COG1126	abc transporter atp-binding protein
CLQ46_RS12120	COG2197	response regulator
CLQ46_RS12135	COG2197	response regulator
CLQ46_RS12175	COG3318	Belongs to the UPF0149 family
CLQ46_RS12175	COG3012	SEC-C Motif Domain Protein
CLQ46_RS12180	COG0814	amino acid
CLQ46_RS12190	COG1528	Iron-storage protein
CLQ46_RS12205	COG0477	Major facilitator Superfamily
CLQ46_RS12215	COG2211	Major facilitator Superfamily
CLQ46_RS12225	COG1528	Iron-storage protein
CLQ46_RS12235	COG1879	ABC-type sugar transport system periplasmic component
CLQ46_RS12245	COG1172	Belongs to the binding-protein-dependent transport system permease family
CLQ46_RS12270	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
CLQ46_RS12280	COG3102	Protein conserved in bacteria
CLQ46_RS12300	COG3788	relative of glutathione S-transferase, MAPEG superfamily
CLQ46_RS12305	COG1801	Protein of unknown function DUF72
CLQ46_RS12310	COG1335	isochorismatase
CLQ46_RS12320	COG0494	nUDIX hydrolase
CLQ46_RS12345	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CLQ46_RS12355	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
CLQ46_RS12360	COG0739	heme binding
CLQ46_RS12365	COG1560	Kdo2-lipid A biosynthetic process
CLQ46_RS12375	COG1737	Transcriptional regulator
CLQ46_RS12390	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
CLQ46_RS12395	COG0129	dihydroxy-acid dehydratase activity
CLQ46_RS12400	COG0800	Aldolase
CLQ46_RS12410	COG3141	response to X-ray
CLQ46_RS12415	COG2979	Protein of unknown function (DUF533)
CLQ46_RS12420	COG1770	oligopeptidase
CLQ46_RS12425	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CLQ46_RS12435	COG2372	response to copper ion
CLQ46_RS12440	COG1276	copper resistance
CLQ46_RS12455	COG2990	Protein conserved in bacteria
CLQ46_RS12480	COG3008	intermembrane lipid transfer
CLQ46_RS12485	COG2995	paraquat-inducible protein a
CLQ46_RS12490	COG1956	GAF domain-containing protein
CLQ46_RS12510	COG2814	Major facilitator Superfamily
CLQ46_RS12520	COG1414	Transcriptional regulator
CLQ46_RS12560	COG0768	penicillin binding
CLQ46_RS12565	COG2226	methyltransferase
CLQ46_RS12580	COG3716	PTS system mannose fructose sorbose family IID component
CLQ46_RS12585	COG3715	PTS system
CLQ46_RS12590	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CLQ46_RS12590	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
CLQ46_RS12595	COG1253	flavin adenine dinucleotide binding
CLQ46_RS12600	COG2200	EAL domain
CLQ46_RS12605	COG1760	l-serine dehydratase
CLQ46_RS12625	COG0251	oxidation-reduction process
CLQ46_RS12630	COG1199	ATP-dependent helicase activity
CLQ46_RS12640	COG3065	identical protein binding
CLQ46_RS12650	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
CLQ46_RS12660	COG2894	cell division
CLQ46_RS12675	COG0179	Fumarylacetoacetate (FAA) hydrolase
CLQ46_RS12705	COG2719	SpoVR family
CLQ46_RS12725	COG1619	proteins homologs of microcin C7 resistance protein MccF
CLQ46_RS12735	COG4774	siderophore transport
CLQ46_RS12750	COG2308	Evidence 4 Homologs of previously reported genes of
CLQ46_RS12790	COG0583	DNA-binding transcription factor activity
CLQ46_RS12795	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CLQ46_RS12810	COG1882	Formate acetyltransferase
CLQ46_RS12840	COG0583	DNA-binding transcription factor activity
CLQ46_RS12870	COG0583	DNA-binding transcription factor activity
CLQ46_RS12885	COG3122	Protein conserved in bacteria
CLQ46_RS12915	COG2885	chlorophyll binding
CLQ46_RS13065	COG0012	GTP binding
CLQ46_RS13085	COG0659	secondary active sulfate transmembrane transporter activity
CLQ46_RS13120	COG2890	protein-(glutamine-N5) methyltransferase activity
CLQ46_RS13140	COG0387	Pfam Sodium calcium exchanger
CLQ46_RS13145	COG4572	Cation transport regulator
CLQ46_RS13150	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
CLQ46_RS13160	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
CLQ46_RS13165	COG3707	response regulator
CLQ46_RS13170	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CLQ46_RS13180	COG1116	anion transmembrane transporter activity
CLQ46_RS13185	COG2146	nitrite reductase [NAD(P)H] activity
CLQ46_RS13185	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CLQ46_RS13190	COG0243	molybdopterin cofactor binding
CLQ46_RS13195	COG4932	domain protein
CLQ46_RS13200	COG2197	response regulator
CLQ46_RS13205	COG3850	Histidine kinase
CLQ46_RS13210	COG2223	nitrite transmembrane transporter activity
CLQ46_RS13215	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
CLQ46_RS13220	COG1140	nitrate reductase beta subunit
CLQ46_RS13225	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
CLQ46_RS13230	COG2181	nitrate reductase activity
CLQ46_RS13240	COG1522	sequence-specific DNA binding
CLQ46_RS13275	COG0788	formyltetrahydrofolate deformylase activity
CLQ46_RS13285	COG1752	Esterase of the alpha-beta hydrolase superfamily
CLQ46_RS13290	COG0745	RESPONSE REGULATOR receiver
CLQ46_RS13295	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CLQ46_RS13300	COG2916	Histone family protein nucleoid-structuring protein H-NS
CLQ46_RS13305	COG1435	thymidine kinase activity
CLQ46_RS13310	COG1454	alcohol dehydrogenase
CLQ46_RS13310	COG1012	belongs to the aldehyde dehydrogenase family
CLQ46_RS13320	COG2095	MarC family integral membrane protein
CLQ46_RS13325	COG4166	transmembrane transport
CLQ46_RS13330	COG0601	transmembrane transport
CLQ46_RS13335	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CLQ46_RS13340	COG0444	Belongs to the ABC transporter superfamily
CLQ46_RS13350	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CLQ46_RS13370	COG2353	YceI-like domain
CLQ46_RS13375	COG2350	Protein conserved in bacteria
CLQ46_RS13385	COG3001	Fructosamine kinase
CLQ46_RS13395	COG1105	Belongs to the carbohydrate kinase PfkB family
CLQ46_RS13400	COG3137	Salt-induced outer membrane protein
CLQ46_RS13440	COG0072	phenylalanine-tRNA ligase activity
CLQ46_RS13440	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CLQ46_RS13460	COG0583	DNA-binding transcription factor activity
CLQ46_RS13480	COG0386	Belongs to the glutathione peroxidase family
CLQ46_RS13490	COG0791	NLP P60 protein
CLQ46_RS13500	COG4256	Hemin uptake protein
CLQ46_RS13505	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CLQ46_RS13515	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CLQ46_RS13515	COG0574	Belongs to the PEP-utilizing enzyme family
CLQ46_RS13525	COG0628	permease
CLQ46_RS13530	COG0247	lactate metabolic process
CLQ46_RS13530	COG0277	FAD linked oxidase domain protein
CLQ46_RS13535	COG2050	protein possibly involved in aromatic compounds catabolism
CLQ46_RS13540	COG2261	transglycosylase associated protein
CLQ46_RS13570	COG1120	ATPase activity
CLQ46_RS13575	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CLQ46_RS13585	COG0583	DNA-binding transcription factor activity
CLQ46_RS13610	COG1304	FMN binding
CLQ46_RS13615	COG1309	transcriptional regulator
CLQ46_RS13630	COG0316	Belongs to the HesB IscA family
CLQ46_RS13635	COG0719	Fe-S assembly protein
CLQ46_RS13640	COG0396	ATPase activity
CLQ46_RS13645	COG0719	Fe-S assembly protein
CLQ46_RS13660	COG1376	ErfK ybiS ycfS ynhG family protein
CLQ46_RS13685	COG1309	transcriptional regulator
CLQ46_RS13690	COG1082	Xylose isomerase domain protein TIM barrel
CLQ46_RS13690	COG3185	4-Hydroxyphenylpyruvate dioxygenase
CLQ46_RS13695	COG2271	Major facilitator Superfamily
CLQ46_RS13700	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CLQ46_RS13710	COG1120	ATPase activity
CLQ46_RS13715	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CLQ46_RS13720	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CLQ46_RS13725	COG1414	Transcriptional regulator
CLQ46_RS13760	COG2814	Major facilitator Superfamily
CLQ46_RS13780	COG0583	DNA-binding transcription factor activity
CLQ46_RS13785	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CLQ46_RS13805	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CLQ46_RS13810	COG1116	anion transmembrane transporter activity
CLQ46_RS13815	COG4774	siderophore transport
CLQ46_RS13820	COG1120	ATPase activity
CLQ46_RS13825	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CLQ46_RS13830	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CLQ46_RS13850	COG0765	amino acid transport
CLQ46_RS13855	COG1126	abc transporter atp-binding protein
CLQ46_RS13885	COG1473	amidohydrolase
CLQ46_RS13890	COG3383	formate dehydrogenase (NAD+) activity
CLQ46_RS13895	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
CLQ46_RS13910	COG1175	transmembrane transport
CLQ46_RS13940	COG4133	protoheme IX ABC transporter activity
CLQ46_RS13945	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CLQ46_RS13950	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CLQ46_RS13965	COG1138	Cytochrome C-type biogenesis protein
CLQ46_RS13970	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CLQ46_RS13975	COG4235	cytochrome complex assembly
CLQ46_RS13975	COG3088	subunit of a heme lyase
CLQ46_RS14015	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
CLQ46_RS14060	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CLQ46_RS14110	COG1028	Short-chain dehydrogenase reductase Sdr
CLQ46_RS14115	COG2610	gluconate transmembrane transporter activity
CLQ46_RS14120	COG1250	3-hydroxyacyl-CoA dehydrogenase
CLQ46_RS14130	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
CLQ46_RS14140	COG0583	DNA-binding transcription factor activity
CLQ46_RS14165	COG0277	FAD linked oxidase domain protein
CLQ46_RS14170	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CLQ46_RS14195	COG0402	S-adenosylhomocysteine deaminase activity
CLQ46_RS14245	COG3321	synthase
CLQ46_RS14245	COG0604	alcohol dehydrogenase
CLQ46_RS14245	COG1028	Short-chain dehydrogenase reductase Sdr
CLQ46_RS14275	COG4608	Belongs to the ABC transporter superfamily
CLQ46_RS14280	COG0444	Belongs to the ABC transporter superfamily
CLQ46_RS14305	COG0346	lactoylglutathione lyase activity
CLQ46_RS14310	COG1349	DNA-binding transcription factor activity
CLQ46_RS14340	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
CLQ46_RS14395	COG0307	riboflavin synthase, alpha
CLQ46_RS14400	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CLQ46_RS14405	COG2814	Major facilitator Superfamily
CLQ46_RS14410	COG0583	DNA-binding transcription factor activity
CLQ46_RS14425	COG2814	Major facilitator Superfamily
CLQ46_RS14440	COG0791	NLP P60 protein
CLQ46_RS14445	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
CLQ46_RS14455	COG0346	lactoylglutathione lyase activity
CLQ46_RS14460	COG1902	pentaerythritol trinitrate reductase activity
CLQ46_RS14465	COG1309	transcriptional regulator
CLQ46_RS14470	COG3313	Fe-S protein
CLQ46_RS14475	COG4989	oxidoreductase activity
CLQ46_RS14480	COG2032	superoxide dismutase activity
CLQ46_RS14485	COG1289	transmembrane transporter activity
CLQ46_RS14490	COG1566	PFAM secretion protein HlyD family protein
CLQ46_RS14505	COG3706	GGDEF domain
CLQ46_RS14520	COG3895	Periplasmic Protein
CLQ46_RS14535	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
CLQ46_RS14540	COG0625	glutathione transferase activity
CLQ46_RS14555	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CLQ46_RS14565	COG4659	FMN binding
CLQ46_RS14600	COG2723	6-phospho-beta-galactosidase activity
CLQ46_RS14610	COG0673	inositol 2-dehydrogenase activity
CLQ46_RS14620	COG2814	Major facilitator Superfamily
CLQ46_RS14640	COG3038	cytochrome b561
CLQ46_RS14660	COG0583	DNA-binding transcription factor activity
CLQ46_RS14665	COG3485	protocatechuate 3,4-dioxygenase
CLQ46_RS14670	COG3485	protocatechuate 3,4-dioxygenase
CLQ46_RS14675	COG5383	Protein conserved in bacteria
CLQ46_RS14680	COG2272	Belongs to the type-B carboxylesterase lipase family
CLQ46_RS14695	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CLQ46_RS14700	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
CLQ46_RS14705	COG1275	C4-dicarboxylate transporter malic acid transport protein
CLQ46_RS14710	COG0500	methyltransferase
CLQ46_RS14725	COG3708	Transcriptional regulator
CLQ46_RS14725	COG2207	Transcriptional regulator
CLQ46_RS14730	COG3135	benzoate transporter
CLQ46_RS14735	COG1396	sequence-specific DNA binding
CLQ46_RS14745	COG0826	peptidase U32
CLQ46_RS14765	COG1294	oxidase, subunit
CLQ46_RS14770	COG1271	oxidase subunit
CLQ46_RS14775	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CLQ46_RS14780	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
CLQ46_RS14785	COG3842	ATPase activity
CLQ46_RS14790	COG1176	ABC-type spermidine putrescine transport system, permease component I
CLQ46_RS14795	COG1177	transmembrane transport
CLQ46_RS14800	COG1012	belongs to the aldehyde dehydrogenase family
CLQ46_RS14830	COG1012	belongs to the aldehyde dehydrogenase family
CLQ46_RS14835	COG0747	negative chemotaxis
CLQ46_RS14845	COG3238	Protein conserved in bacteria
CLQ46_RS14850	COG1247	-acetyltransferase
CLQ46_RS14860	COG2130	NADP-dependent
CLQ46_RS14875	COG3691	Protein conserved in bacteria
CLQ46_RS14880	COG1228	amidohydrolase
CLQ46_RS14885	COG4772	TonB-dependent receptor
CLQ46_RS14910	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
CLQ46_RS14915	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CLQ46_RS14920	COG1473	amidohydrolase
CLQ46_RS14925	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CLQ46_RS14930	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CLQ46_RS14940	COG0765	amino acid transport
CLQ46_RS14945	COG1126	abc transporter atp-binding protein
CLQ46_RS14955	COG0625	glutathione transferase activity
CLQ46_RS14985	COG2211	Major facilitator Superfamily
CLQ46_RS15000	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CLQ46_RS15005	COG3842	ATPase activity
CLQ46_RS15010	COG1840	ABC-type Fe3 transport system, periplasmic component
CLQ46_RS15015	COG1178	ABC-type Fe3 transport system permease component
CLQ46_RS15020	COG2162	N-hydroxyarylamine O-acetyltransferase activity
CLQ46_RS15025	COG2181	nitrate reductase activity
CLQ46_RS15030	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
CLQ46_RS15035	COG1140	nitrate reductase beta subunit
CLQ46_RS15040	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
CLQ46_RS15060	COG1414	Transcriptional regulator
CLQ46_RS15065	COG4948	Mandelate Racemase Muconate Lactonizing
CLQ46_RS15070	COG4829	muconolactone delta-isomerase
CLQ46_RS15075	COG3485	protocatechuate 3,4-dioxygenase
CLQ46_RS15085	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
CLQ46_RS15105	COG0243	molybdopterin cofactor binding
CLQ46_RS15105	COG3383	formate dehydrogenase (NAD+) activity
CLQ46_RS15110	COG3383	formate dehydrogenase (NAD+) activity
CLQ46_RS15110	COG0243	molybdopterin cofactor binding
CLQ46_RS15115	COG0437	4 iron, 4 sulfur cluster binding
CLQ46_RS15120	COG2864	formate dehydrogenase
CLQ46_RS15135	COG2326	polyphosphate kinase activity
CLQ46_RS15145	COG2814	Major facilitator Superfamily
CLQ46_RS15155	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CLQ46_RS15165	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CLQ46_RS15175	COG0747	negative chemotaxis
CLQ46_RS15180	COG1064	alcohol dehydrogenase
CLQ46_RS15195	COG0488	(ABC) transporter
CLQ46_RS15235	COG1028	Short-chain dehydrogenase reductase Sdr
CLQ46_RS15240	COG3729	General stress protein
CLQ46_RS15255	COG3685	Protein conserved in bacteria
CLQ46_RS15265	COG0366	Alpha amylase catalytic
CLQ46_RS15275	COG2323	membrane
CLQ46_RS15285	COG3111	PFAM Bacterial OB fold (BOF) protein
CLQ46_RS15290	COG1764	response to oxidative stress
CLQ46_RS15315	COG3781	membrane
CLQ46_RS15320	COG0243	molybdopterin cofactor binding
CLQ46_RS15325	COG0583	DNA-binding transcription factor activity
CLQ46_RS15330	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CLQ46_RS15355	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CLQ46_RS15360	COG1447	Phosphotransferase system cellobiose-specific component IIA
CLQ46_RS15365	COG2814	Major facilitator Superfamily
CLQ46_RS15375	COG1285	pathogenesis
CLQ46_RS15380	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
CLQ46_RS15390	COG0583	DNA-binding transcription factor activity
CLQ46_RS15410	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CLQ46_RS15410	COG0519	Catalyzes the synthesis of GMP from XMP
CLQ46_RS15450	COG0596	Alpha beta hydrolase
CLQ46_RS15460	COG2205	protein histidine kinase activity
CLQ46_RS15475	COG0076	glutamate decarboxylase activity
CLQ46_RS15480	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CLQ46_RS15485	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CLQ46_RS15490	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CLQ46_RS15495	COG1116	anion transmembrane transporter activity
CLQ46_RS15500	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
CLQ46_RS15510	COG0673	inositol 2-dehydrogenase activity
CLQ46_RS15520	COG1609	Transcriptional regulator
CLQ46_RS15525	COG3706	GGDEF domain
CLQ46_RS15530	COG0402	S-adenosylhomocysteine deaminase activity
CLQ46_RS15535	COG1953	Uracil, thiamine, allantoin
CLQ46_RS15570	COG0406	alpha-ribazole phosphatase activity
CLQ46_RS15580	COG1335	isochorismatase
CLQ46_RS15620	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CLQ46_RS15685	COG0765	amino acid transport
CLQ46_RS15695	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
CLQ46_RS15705	COG2070	2-Nitropropane dioxygenase
CLQ46_RS15710	COG0583	DNA-binding transcription factor activity
CLQ46_RS15720	COG1902	pentaerythritol trinitrate reductase activity
CLQ46_RS15725	COG4529	Protein conserved in bacteria
CLQ46_RS15730	COG0477	Major facilitator Superfamily
CLQ46_RS15760	COG2223	nitrite transmembrane transporter activity
CLQ46_RS15770	COG1609	Transcriptional regulator
CLQ46_RS15775	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CLQ46_RS15785	COG3037	sugar-specific permease SgaT UlaA
CLQ46_RS15790	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CLQ46_RS15800	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CLQ46_RS15805	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CLQ46_RS15805	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CLQ46_RS15805	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
CLQ46_RS15835	COG0583	DNA-binding transcription factor activity
CLQ46_RS15840	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CLQ46_RS15850	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CLQ46_RS15865	COG1172	Belongs to the binding-protein-dependent transport system permease family
CLQ46_RS15875	COG1609	Transcriptional regulator
CLQ46_RS15905	COG1652	LysM domain
CLQ46_RS15920	COG0426	domain, Protein
CLQ46_RS15920	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CLQ46_RS15950	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
CLQ46_RS15950	COG0456	acetyltransferase
CLQ46_RS15960	COG0667	Aldo Keto reductase
CLQ46_RS15965	COG0667	Aldo Keto reductase
CLQ46_RS15975	COG0667	Aldo Keto reductase
CLQ46_RS15990	COG4977	sequence-specific DNA binding
CLQ46_RS16010	COG4977	sequence-specific DNA binding
CLQ46_RS16015	COG1349	DNA-binding transcription factor activity
CLQ46_RS16030	COG1349	DNA-binding transcription factor activity
CLQ46_RS16035	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CLQ46_RS16040	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CLQ46_RS16045	COG0738	Major facilitator superfamily
CLQ46_RS16090	COG1929	Belongs to the glycerate kinase type-1 family
CLQ46_RS16095	COG3835	regulator
CLQ46_RS16115	COG2186	Transcriptional regulator
CLQ46_RS16120	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CLQ46_RS16120	COG1263	PTS System
CLQ46_RS16135	COG2814	Major facilitator Superfamily
CLQ46_RS16140	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
CLQ46_RS16140	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CLQ46_RS16150	COG2819	hydrolase of the alpha beta superfamily
CLQ46_RS16155	COG5001	Diguanylate cyclase
CLQ46_RS16155	COG3300	MHYT domain
CLQ46_RS16190	COG3188	usher protein
CLQ46_RS16200	COG1649	PFAM Uncharacterised BCR, COG1649
CLQ46_RS16205	COG3550	peptidyl-serine autophosphorylation
CLQ46_RS16210	COG1396	sequence-specific DNA binding
CLQ46_RS16215	COG2351	hydroxyisourate hydrolase activity
CLQ46_RS16220	COG3648	Uricase
CLQ46_RS16220	COG3195	allantoin biosynthetic process
CLQ46_RS16225	COG2233	PERMEase
CLQ46_RS16255	COG2207	Transcriptional regulator
CLQ46_RS16270	COG4628	conserved protein (DUF2132)
CLQ46_RS16290	COG2011	ABC-type metal ion transport system permease component
CLQ46_RS16295	COG2070	2-Nitropropane dioxygenase
CLQ46_RS16305	COG0477	Major facilitator Superfamily
CLQ46_RS16385	COG2199	diguanylate cyclase activity
CLQ46_RS16400	COG1012	belongs to the aldehyde dehydrogenase family
CLQ46_RS16405	COG0583	DNA-binding transcription factor activity
CLQ46_RS16415	COG0039	L-malate dehydrogenase activity
CLQ46_RS16420	COG1349	DNA-binding transcription factor activity
CLQ46_RS16425	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
CLQ46_RS16430	COG3395	kinase activity
CLQ46_RS16440	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CLQ46_RS16455	COG2731	YhcH YjgK YiaL family protein
CLQ46_RS16460	COG1028	Short-chain dehydrogenase reductase Sdr
CLQ46_RS16485	COG4977	sequence-specific DNA binding
CLQ46_RS16495	COG0697	spore germination
CLQ46_RS16500	COG2814	Major facilitator Superfamily
CLQ46_RS16510	COG0410	ABC transporter
CLQ46_RS16515	COG1129	ABC transporter
CLQ46_RS16530	COG0683	leucine binding
CLQ46_RS16535	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
CLQ46_RS16570	COG2223	nitrite transmembrane transporter activity
CLQ46_RS16575	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
CLQ46_RS16590	COG1349	DNA-binding transcription factor activity
CLQ46_RS16600	COG2084	Dehydrogenase
CLQ46_RS16605	COG3395	kinase activity
CLQ46_RS16610	COG0235	Class ii aldolase
CLQ46_RS16615	COG3622	Belongs to the hyi family
CLQ46_RS16620	COG2610	gluconate transmembrane transporter activity
CLQ46_RS16625	COG2207	Transcriptional regulator
CLQ46_RS16625	COG3708	Transcriptional regulator
CLQ46_RS16640	COG2200	EAL domain
CLQ46_RS16645	COG1546	Belongs to the CinA family
CLQ46_RS16650	COG0071	Belongs to the small heat shock protein (HSP20) family
CLQ46_RS16660	COG2197	response regulator
CLQ46_RS16665	COG2135	peptidase activity
CLQ46_RS16670	COG2207	Transcriptional regulator
CLQ46_RS16685	COG4221	oxidoreductase activity
CLQ46_RS16690	COG1802	Transcriptional regulator
CLQ46_RS16695	COG0589	response to stress
CLQ46_RS16700	COG0246	Mannitol dehydrogenase
CLQ46_RS16705	COG2271	Major facilitator Superfamily
CLQ46_RS16720	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CLQ46_RS16735	COG0243	molybdopterin cofactor binding
CLQ46_RS16740	COG0437	4 iron, 4 sulfur cluster binding
CLQ46_RS16745	COG3302	dmso reductase anchor subunit
CLQ46_RS16760	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
CLQ46_RS16765	COG1940	carbohydrate kinase activity
CLQ46_RS16770	COG0583	DNA-binding transcription factor activity
CLQ46_RS16775	COG2814	Major facilitator Superfamily
CLQ46_RS16780	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
CLQ46_RS16790	COG3591	Belongs to the peptidase S1B family
CLQ46_RS16810	COG0628	permease
CLQ46_RS16840	COG0679	Auxin Efflux Carrier
CLQ46_RS16850	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
CLQ46_RS16875	COG3290	protein histidine kinase activity
CLQ46_RS16880	COG4565	transcriptional regulatory protein
CLQ46_RS16905	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
CLQ46_RS16905	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
CLQ46_RS16925	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CLQ46_RS16930	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CLQ46_RS16940	COG0183	Belongs to the thiolase family
CLQ46_RS16945	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
CLQ46_RS16955	COG1414	Transcriptional regulator
CLQ46_RS16960	COG2840	Smr protein MutS2
CLQ46_RS16965	COG0583	DNA-binding transcription factor activity
CLQ46_RS16975	COG1473	amidohydrolase
CLQ46_RS16980	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
CLQ46_RS16995	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CLQ46_RS17010	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
CLQ46_RS17015	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
CLQ46_RS17035	COG0531	amino acid
CLQ46_RS17045	COG3136	membrane protein required for alginate biosynthesis
CLQ46_RS17050	COG0745	RESPONSE REGULATOR receiver
CLQ46_RS17060	COG2205	protein histidine kinase activity
CLQ46_RS17070	COG0114	fumarate hydratase activity
CLQ46_RS17075	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
CLQ46_RS17075	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
CLQ46_RS17080	COG1482	cell wall glycoprotein biosynthetic process
CLQ46_RS17085	COG5339	Protein conserved in bacteria
CLQ46_RS17090	COG1609	Transcriptional regulator
CLQ46_RS17095	COG1263	PTS System
CLQ46_RS17095	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CLQ46_RS17100	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
CLQ46_RS17125	COG2391	methyltransferase activity
CLQ46_RS17130	COG0425	Belongs to the sulfur carrier protein TusA family
CLQ46_RS17135	COG5562	phage envelope protein
CLQ46_RS17140	COG0401	homolog of Blt101
CLQ46_RS17145	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CLQ46_RS17150	COG1012	belongs to the aldehyde dehydrogenase family
CLQ46_RS17155	COG1434	Gram-negative-bacterium-type cell wall biogenesis
CLQ46_RS17160	COG0477	Major facilitator Superfamily
CLQ46_RS17165	COG1113	amino acid transport
CLQ46_RS17170	COG2988	succinylglutamate desuccinylase activity
CLQ46_RS17175	COG3724	N-succinylarginine dihydrolase activity
CLQ46_RS17180	COG1012	belongs to the aldehyde dehydrogenase family
CLQ46_RS17185	COG3138	arginine N-succinyltransferase
CLQ46_RS17190	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CLQ46_RS17195	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CLQ46_RS17200	COG0667	Aldo Keto reductase
CLQ46_RS17205	COG0583	DNA-binding transcription factor activity
CLQ46_RS17230	COG4122	O-methyltransferase activity
CLQ46_RS17235	COG1643	Atp-dependent helicase
CLQ46_RS17250	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
CLQ46_RS17255	COG3327	negative regulation of DNA-templated transcription, initiation
CLQ46_RS17260	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
CLQ46_RS17265	COG0183	Belongs to the thiolase family
CLQ46_RS17270	COG2050	protein possibly involved in aromatic compounds catabolism
CLQ46_RS17275	COG1250	3-hydroxyacyl-CoA dehydrogenase
CLQ46_RS17280	COG1024	Enoyl-CoA hydratase
CLQ46_RS17285	COG1024	Enoyl-CoA hydratase
CLQ46_RS17290	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CLQ46_RS17295	COG2151	metal-sulfur cluster biosynthetic enzyme
CLQ46_RS17300	COG3396	Phenylacetate-CoA oxygenase
CLQ46_RS17305	COG3460	Phenylacetate-CoA oxygenase
CLQ46_RS17310	COG3396	Phenylacetate-CoA oxygenase
CLQ46_RS17315	COG2030	dehydratase
CLQ46_RS17315	COG1012	belongs to the aldehyde dehydrogenase family
CLQ46_RS17345	COG1012	belongs to the aldehyde dehydrogenase family
CLQ46_RS17350	COG2207	Transcriptional regulator
CLQ46_RS17355	COG3784	Protein of unknown function (DUF1318)
CLQ46_RS17365	COG2911	Protein conserved in bacteria
CLQ46_RS17370	COG0586	Pfam SNARE associated Golgi protein
CLQ46_RS17375	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CLQ46_RS17380	COG3187	Heat shock protein
CLQ46_RS17385	COG3042	response to heat
CLQ46_RS17395	COG1013	pyruvate-flavodoxin oxidoreductase activity
CLQ46_RS17395	COG0674	pyruvate-flavodoxin oxidoreductase activity
CLQ46_RS17395	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CLQ46_RS17395	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
CLQ46_RS17400	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CLQ46_RS17410	COG0589	response to stress
CLQ46_RS17420	COG0513	Belongs to the DEAD box helicase family
CLQ46_RS17440	COG1349	DNA-binding transcription factor activity
CLQ46_RS17445	COG0673	inositol 2-dehydrogenase activity
CLQ46_RS17460	COG1113	amino acid transport
CLQ46_RS17465	COG1522	sequence-specific DNA binding
CLQ46_RS17475	COG1448	Aminotransferase
CLQ46_RS17480	COG2011	ABC-type metal ion transport system permease component
CLQ46_RS17495	COG0436	Aminotransferase
CLQ46_RS17500	COG0604	alcohol dehydrogenase
CLQ46_RS17525	COG0583	DNA-binding transcription factor activity
CLQ46_RS17545	COG1028	Short-chain dehydrogenase reductase Sdr
CLQ46_RS17550	COG1309	transcriptional regulator
CLQ46_RS17555	COG1028	Short-chain dehydrogenase reductase Sdr
CLQ46_RS17650	COG2885	chlorophyll binding
CLQ46_RS17685	COG0582	viral genome integration into host DNA
CLQ46_RS17690	COG0693	protein deglycase activity
CLQ46_RS17695	COG1078	dGTPase activity
CLQ46_RS17700	COG1028	Short-chain dehydrogenase reductase Sdr
CLQ46_RS17705	COG0583	DNA-binding transcription factor activity
CLQ46_RS17725	COG0656	L-ascorbic acid biosynthetic process
CLQ46_RS17755	COG4166	transmembrane transport
CLQ46_RS17760	COG2866	Carboxypeptidase
CLQ46_RS17765	COG4948	Mandelate Racemase Muconate Lactonizing
CLQ46_RS17770	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
CLQ46_RS17775	COG3180	Ammonia monooxygenase
CLQ46_RS17785	COG1486	melibiose metabolic process
CLQ46_RS17790	COG0583	DNA-binding transcription factor activity
CLQ46_RS17800	COG3106	COG3106 Predicted ATPase
CLQ46_RS17810	COG1983	PspC domain protein
CLQ46_RS17820	COG1842	Phage shock protein A
CLQ46_RS17825	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
CLQ46_RS17835	COG1473	amidohydrolase
CLQ46_RS17850	COG0702	epimerase
CLQ46_RS17865	COG2135	peptidase activity
CLQ46_RS17875	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CLQ46_RS17880	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CLQ46_RS17885	COG3344	reverse transcriptase
CLQ46_RS17970	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
CLQ46_RS18085	COG4171	peptide transport system, permease
CLQ46_RS18100	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
CLQ46_RS18110	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
CLQ46_RS18115	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CLQ46_RS18115	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CLQ46_RS18130	COG1349	DNA-binding transcription factor activity
CLQ46_RS18140	COG0023	Translation Initiation Factor
CLQ46_RS18150	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
CLQ46_RS18155	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
CLQ46_RS18160	COG0671	phosphoesterase, PA-phosphatase related
CLQ46_RS18170	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
CLQ46_RS18200	COG0616	signal peptide processing
CLQ46_RS18210	COG1028	Short-chain dehydrogenase reductase Sdr
CLQ46_RS18215	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
CLQ46_RS18225	COG0583	DNA-binding transcription factor activity
CLQ46_RS18235	COG0009	L-threonylcarbamoyladenylate synthase
CLQ46_RS18245	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CLQ46_RS18250	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CLQ46_RS18250	COG0512	Glutamine amidotransferase of anthranilate synthase
CLQ46_RS18255	COG0135	phosphoribosylanthranilate isomerase activity
CLQ46_RS18255	COG0134	indole-3-glycerol-phosphate synthase activity
CLQ46_RS18310	COG4774	siderophore transport
CLQ46_RS18320	COG3047	cAMP biosynthetic process
CLQ46_RS18325	COG0727	PFAM Uncharacterised protein family (UPF0153)
CLQ46_RS18355	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CLQ46_RS18360	COG1028	Short-chain dehydrogenase reductase Sdr
CLQ46_RS18365	COG1988	membrane-bound metal-dependent
CLQ46_RS18370	COG1823	symporter activity
CLQ46_RS18380	COG0753	catalase activity
CLQ46_RS18390	COG1486	melibiose metabolic process
CLQ46_RS18395	COG1917	Cupin 2, conserved barrel domain protein
CLQ46_RS18395	COG2169	Transcriptional regulator
CLQ46_RS18400	COG1447	Phosphotransferase system cellobiose-specific component IIA
CLQ46_RS18405	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CLQ46_RS18410	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CLQ46_RS18415	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CLQ46_RS18425	COG0322	excinuclease ABC activity
CLQ46_RS18430	COG3678	ATP-independent chaperone mediated protein folding
CLQ46_RS18440	COG3724	N-succinylarginine dihydrolase activity
CLQ46_RS18450	COG3138	arginine N-succinyltransferase
CLQ46_RS18460	COG0708	Exodeoxyribonuclease III
CLQ46_RS18465	COG0398	Pfam SNARE associated Golgi protein
CLQ46_RS18470	COG0398	Pfam SNARE associated Golgi protein
CLQ46_RS18475	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CLQ46_RS18480	COG4134	Bacterial extracellular solute-binding protein
CLQ46_RS18485	COG4135	transport system, permease component
CLQ46_RS18490	COG4136	ATPase activity
CLQ46_RS18495	COG2897	thiosulfate sulfurtransferase activity
CLQ46_RS18500	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CLQ46_RS18505	COG0494	nUDIX hydrolase
CLQ46_RS18510	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CLQ46_RS18515	COG1028	Short-chain dehydrogenase reductase Sdr
CLQ46_RS18515	COG0604	alcohol dehydrogenase
CLQ46_RS18515	COG3321	synthase
CLQ46_RS18520	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CLQ46_RS18525	COG0709	Synthesizes selenophosphate from selenide and ATP
CLQ46_RS18545	COG0778	Nitroreductase
CLQ46_RS18550	COG0616	signal peptide processing
CLQ46_RS18555	COG0252	asparaginase activity
CLQ46_RS18560	COG1335	isochorismatase
CLQ46_RS18565	COG2814	Major facilitator Superfamily
CLQ46_RS18570	COG1349	DNA-binding transcription factor activity
CLQ46_RS18575	COG0667	Aldo Keto reductase
CLQ46_RS18580	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CLQ46_RS18585	COG0191	fructose-bisphosphate aldolase activity
CLQ46_RS18590	COG1063	alcohol dehydrogenase
CLQ46_RS18595	COG2271	Major facilitator Superfamily
CLQ46_RS18600	COG1063	alcohol dehydrogenase
CLQ46_RS18615	COG3139	Protein of unknown function (DUF1315)
CLQ46_RS18640	COG3713	MltA-interacting MipA family protein
CLQ46_RS18645	COG2766	serine protein kinase
CLQ46_RS18660	COG0386	Belongs to the glutathione peroxidase family
CLQ46_RS18680	COG1028	Short-chain dehydrogenase reductase Sdr
CLQ46_RS18685	COG0583	DNA-binding transcription factor activity
CLQ46_RS18690	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CLQ46_RS18695	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CLQ46_RS18700	COG3344	reverse transcriptase
CLQ46_RS18715	COG0859	PFAM glycosyl transferase family 9
CLQ46_RS18720	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CLQ46_RS18730	COG2207	Transcriptional regulator
CLQ46_RS18735	COG2807	transmembrane transport
CLQ46_RS18740	COG0504	CTP synthase activity
CLQ46_RS18745	COG1683	Conserved Protein
CLQ46_RS18750	COG3189	MarR family transcriptional regulator
CLQ46_RS18755	COG3042	response to heat
CLQ46_RS18760	COG2203	Gaf domain
CLQ46_RS18760	COG2199	diguanylate cyclase activity
CLQ46_RS18780	COG3182	Iron-regulated membrane protein
CLQ46_RS18790	COG1560	Kdo2-lipid A biosynthetic process
CLQ46_RS18805	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
CLQ46_RS18810	COG3706	GGDEF domain
CLQ46_RS18815	COG0583	DNA-binding transcription factor activity
CLQ46_RS18820	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
CLQ46_RS18845	COG1294	oxidase, subunit
CLQ46_RS18850	COG1271	oxidase subunit
CLQ46_RS18855	COG3546	catalase activity
CLQ46_RS18860	COG3685	Protein conserved in bacteria
CLQ46_RS18865	COG3685	Protein conserved in bacteria
CLQ46_RS18870	COG3729	General stress protein
CLQ46_RS18875	COG1063	alcohol dehydrogenase
CLQ46_RS18880	COG3813	Protein conserved in bacteria
CLQ46_RS18895	COG0640	Transcriptional regulator
CLQ46_RS18900	COG0538	isocitrate dehydrogenase activity
CLQ46_RS18990	COG0616	signal peptide processing
CLQ46_RS19005	COG1802	Transcriptional regulator
CLQ46_RS19005	COG4626	Terminase
CLQ46_RS19045	COG3772	lysozyme
CLQ46_RS19070	COG1403	HNH endonuclease
CLQ46_RS19095	COG3344	reverse transcriptase
CLQ46_RS19105	COG0232	Belongs to the dGTPase family. Type 2 subfamily
CLQ46_RS19150	COG1396	sequence-specific DNA binding
CLQ46_RS19175	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CLQ46_RS19185	COG0582	viral genome integration into host DNA
CLQ46_RS19190	COG0538	isocitrate dehydrogenase activity
CLQ46_RS19195	COG1187	pseudouridine synthase activity
CLQ46_RS19215	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CLQ46_RS19235	COG2205	protein histidine kinase activity
CLQ46_RS19240	COG2850	peptidyl-arginine hydroxylation
CLQ46_RS19260	COG1177	transmembrane transport
CLQ46_RS19275	COG0318	PFAM AMP-dependent synthetase and ligase
CLQ46_RS19285	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
CLQ46_RS19295	COG4591	ABC-type transport system involved in lipoprotein release permease component
CLQ46_RS19305	COG4591	ABC-type transport system involved in lipoprotein release permease component
CLQ46_RS19315	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CLQ46_RS19320	COG1376	ErfK ybiS ycfS ynhG family protein
CLQ46_RS19320	COG1388	LysM domain
CLQ46_RS19330	COG1309	transcriptional regulator
CLQ46_RS19340	COG3134	Outer membrane lipoprotein
CLQ46_RS19345	COG1252	NADH dehydrogenase
CLQ46_RS19370	COG5633	Lipoprotein
CLQ46_RS19375	COG0537	adenosine 5'-monophosphoramidase activity
CLQ46_RS19385	COG0084	hydrolase, TatD family'
CLQ46_RS19390	COG0470	DNA polymerase III
CLQ46_RS19400	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CLQ46_RS19405	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CLQ46_RS19410	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CLQ46_RS19425	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
CLQ46_RS19445	COG1399	metal-binding, possibly nucleic acid-binding protein
CLQ46_RS19465	COG1530	ribonuclease E activity
CLQ46_RS19470	COG0583	DNA-binding transcription factor activity
CLQ46_RS19475	COG2814	Major facilitator Superfamily
CLQ46_RS19495	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CLQ46_RS19545	COG1560	Kdo2-lipid A biosynthetic process
CLQ46_RS19565	COG5645	(Lipo)protein
CLQ46_RS19605	COG3381	protein complex oligomerization
CLQ46_RS19630	COG0583	DNA-binding transcription factor activity
CLQ46_RS19640	COG1335	isochorismatase
CLQ46_RS19650	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CLQ46_RS19655	COG1702	phosphate starvation-inducible protein PhoH
CLQ46_RS19675	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CLQ46_RS19685	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CLQ46_RS19705	COG1309	transcriptional regulator
CLQ46_RS19740	COG2233	PERMEase
CLQ46_RS19750	COG3729	General stress protein
CLQ46_RS19775	COG1028	Short-chain dehydrogenase reductase Sdr
CLQ46_RS19790	COG0531	amino acid
CLQ46_RS19800	COG0174	glutamine synthetase
CLQ46_RS19805	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
CLQ46_RS19810	COG1917	Cupin 2, conserved barrel domain protein
CLQ46_RS19810	COG1396	sequence-specific DNA binding
CLQ46_RS19815	COG1012	belongs to the aldehyde dehydrogenase family
CLQ46_RS19820	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CLQ46_RS19825	COG0583	DNA-binding transcription factor activity
CLQ46_RS19830	COG0473	3-isopropylmalate dehydrogenase activity
CLQ46_RS19840	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CLQ46_RS19845	COG4638	Rieske (2fe-2S)
CLQ46_RS19850	COG1012	belongs to the aldehyde dehydrogenase family
CLQ46_RS19855	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CLQ46_RS19865	COG2200	EAL domain
CLQ46_RS19870	COG2200	EAL domain
CLQ46_RS19885	COG0670	Belongs to the BI1 family
CLQ46_RS19900	COG2207	Transcriptional regulator
CLQ46_RS19905	COG1881	PFAM PEBP family protein
CLQ46_RS19920	COG1832	CoA-binding protein
CLQ46_RS19930	COG0210	DNA helicase
CLQ46_RS19935	COG3304	Inner membrane component domain
CLQ46_RS19940	COG1289	transmembrane transporter activity
CLQ46_RS19945	COG3070	regulator of competence-specific genes
CLQ46_RS19970	COG1067	ATP-dependent peptidase activity
CLQ46_RS19980	COG3130	regulation of translation
CLQ46_RS19990	COG3009	Protein conserved in bacteria
CLQ46_RS19995	COG3008	intermembrane lipid transfer
CLQ46_RS19995	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
CLQ46_RS20000	COG2995	paraquat-inducible protein a
CLQ46_RS20005	COG0488	(ABC) transporter
CLQ46_RS20015	COG0633	Ferredoxin
CLQ46_RS20015	COG3217	Mosc domain protein beta barrel domain protein
CLQ46_RS20030	COG0431	NADPH-dependent FMN reductase
CLQ46_RS20035	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CLQ46_RS20040	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CLQ46_RS20045	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CLQ46_RS20055	COG0308	aminopeptidase N
CLQ46_RS20070	COG1473	amidohydrolase
CLQ46_RS20080	COG0814	amino acid
CLQ46_RS20090	COG1522	sequence-specific DNA binding
CLQ46_RS20105	COG1448	Aminotransferase
CLQ46_RS20110	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CLQ46_RS20115	COG3108	Peptidase M15
CLQ46_RS20125	COG2989	Protein conserved in bacteria
CLQ46_RS20135	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
CLQ46_RS20145	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CLQ46_RS20150	COG1434	Gram-negative-bacterium-type cell wall biogenesis
CLQ46_RS20155	COG3173	Aminoglycoside phosphotransferase
CLQ46_RS20170	COG3214	Protein conserved in bacteria
CLQ46_RS20185	COG0658	competence protein
CLQ46_RS20185	COG2333	competence protein COMEC
CLQ46_RS20195	COG0539	negative regulation of cytoplasmic translation
CLQ46_RS20215	COG2323	membrane
CLQ46_RS20220	COG1944	ATP diphosphatase activity
CLQ46_RS20225	COG2116	formate transmembrane transporter activity
CLQ46_RS20230	COG1882	Formate acetyltransferase
CLQ46_RS20235	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
CLQ46_RS20240	COG0477	Major facilitator Superfamily
CLQ46_RS20250	COG3302	dmso reductase anchor subunit
CLQ46_RS20255	COG0437	4 iron, 4 sulfur cluster binding
CLQ46_RS20260	COG0243	molybdopterin cofactor binding
CLQ46_RS20270	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CLQ46_RS20280	COG1674	ftsk spoiiie
CLQ46_RS20280	COG1178	ABC-type Fe3 transport system permease component
CLQ46_RS20290	COG0492	ferredoxin-NADP+ reductase activity
CLQ46_RS20295	COG4988	ABC transporter
CLQ46_RS20300	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
CLQ46_RS20315	COG0542	response to heat
CLQ46_RS20325	COG1278	Cold shock
CLQ46_RS20340	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CLQ46_RS20345	COG3593	DNA synthesis involved in DNA repair
CLQ46_RS20355	COG2431	L-lysine efflux transmembrane transporter activity
CLQ46_RS20365	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CLQ46_RS20380	COG0028	Belongs to the TPP enzyme family
CLQ46_RS20385	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
CLQ46_RS20390	COG0702	epimerase
CLQ46_RS20395	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CLQ46_RS20400	COG3023	N-Acetylmuramoyl-L-alanine amidase
CLQ46_RS20405	COG4251	negative regulation of phosphorylation
CLQ46_RS20405	COG5001	Diguanylate cyclase
CLQ46_RS20405	COG3706	GGDEF domain
CLQ46_RS20405	COG2203	Gaf domain
CLQ46_RS20420	COG1126	abc transporter atp-binding protein
CLQ46_RS20425	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CLQ46_RS20430	COG4215	(ABC) transporter
CLQ46_RS20435	COG4160	amino acid transport
CLQ46_RS20440	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CLQ46_RS20445	COG5002	protein histidine kinase activity
CLQ46_RS20450	COG0745	RESPONSE REGULATOR receiver
CLQ46_RS20465	COG1177	transmembrane transport
CLQ46_RS20470	COG1176	ABC-type spermidine putrescine transport system, permease component I
CLQ46_RS20475	COG3842	ATPase activity
CLQ46_RS20480	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
CLQ46_RS20665	COG4695	Portal protein
CLQ46_RS20700	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
CLQ46_RS20740	COG3344	reverse transcriptase
CLQ46_RS20750	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
CLQ46_RS20755	COG3226	Transcriptional regulator
CLQ46_RS20760	COG0738	Major facilitator superfamily
CLQ46_RS20765	COG0561	phosphatase activity
CLQ46_RS20770	COG2814	Major facilitator Superfamily
CLQ46_RS20780	COG0671	phosphoesterase, PA-phosphatase related
CLQ46_RS20785	COG1349	DNA-binding transcription factor activity
CLQ46_RS20790	COG1686	Belongs to the peptidase S11 family
CLQ46_RS20795	COG0625	glutathione transferase activity
CLQ46_RS20800	COG2133	pyrroloquinoline quinone binding
CLQ46_RS20810	COG2223	nitrite transmembrane transporter activity
CLQ46_RS20835	COG0747	negative chemotaxis
CLQ46_RS20850	COG0303	'Molybdopterin
CLQ46_RS20855	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CLQ46_RS20860	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
CLQ46_RS20865	COG1882	Formate acetyltransferase
CLQ46_RS20870	COG0561	phosphatase activity
CLQ46_RS20880	COG1609	Transcriptional regulator
CLQ46_RS20885	COG2271	Major facilitator Superfamily
CLQ46_RS20900	COG0488	(ABC) transporter
CLQ46_RS20905	COG2365	Tyrosine phosphatase family
CLQ46_RS20910	COG1376	ErfK ybiS ycfS ynhG family protein
CLQ46_RS20915	COG2188	Transcriptional regulator
CLQ46_RS20920	COG2723	6-phospho-beta-galactosidase activity
CLQ46_RS20925	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
CLQ46_RS20930	COG1321	iron dependent repressor
CLQ46_RS20940	COG2194	sulfuric ester hydrolase activity
CLQ46_RS20945	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
CLQ46_RS20960	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CLQ46_RS20965	COG0765	amino acid transport
CLQ46_RS20970	COG1126	abc transporter atp-binding protein
CLQ46_RS20975	COG0668	transmembrane transport
CLQ46_RS20985	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CLQ46_RS20995	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
CLQ46_RS21005	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CLQ46_RS21010	COG1199	ATP-dependent helicase activity
CLQ46_RS21015	COG0513	Belongs to the DEAD box helicase family
CLQ46_RS21020	COG3958	Transketolase
CLQ46_RS21025	COG3959	Transketolase, thiamine diphosphate binding domain
CLQ46_RS21030	COG1028	Short-chain dehydrogenase reductase Sdr
CLQ46_RS21035	COG2271	Major facilitator Superfamily
CLQ46_RS21040	COG0583	DNA-binding transcription factor activity
CLQ46_RS21045	COG1309	transcriptional regulator
CLQ46_RS21050	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CLQ46_RS21055	COG1131	(ABC) transporter
CLQ46_RS21060	COG0842	Transport permease protein
CLQ46_RS21065	COG0842	Transport permease protein
CLQ46_RS21080	COG3568	Endonuclease Exonuclease Phosphatase
CLQ46_RS21085	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CLQ46_RS21090	COG0392	lysyltransferase activity
CLQ46_RS21105	COG0670	Belongs to the BI1 family
CLQ46_RS21110	COG0314	molybdopterin synthase activity
CLQ46_RS21115	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
CLQ46_RS21125	COG0521	Mo-molybdopterin cofactor biosynthetic process
CLQ46_RS21150	COG0745	RESPONSE REGULATOR receiver
CLQ46_RS21155	COG0642	Histidine kinase
CLQ46_RS21190	COG2226	methyltransferase
CLQ46_RS21210	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CLQ46_RS21215	COG1881	PFAM PEBP family protein
CLQ46_RS21255	COG4677	pectinesterase activity
CLQ46_RS21285	COG0789	Transcriptional regulator
CLQ46_RS21290	COG2200	EAL domain
CLQ46_RS21315	COG0561	phosphatase activity
CLQ46_RS21320	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
CLQ46_RS21325	COG4149	molybdate abc transporter
CLQ46_RS21330	COG0725	ABC transporter, periplasmic molybdate-binding protein
CLQ46_RS21340	COG3585	molybdate ion transport
CLQ46_RS21340	COG2005	Transcriptional regulator
CLQ46_RS21345	COG1119	ATPase activity
CLQ46_RS21355	COG1085	galactose-1-phosphate uridylyltransferase
CLQ46_RS21365	COG2017	converts alpha-aldose to the beta-anomer
CLQ46_RS21375	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CLQ46_RS21390	COG3201	nicotinamide mononucleotide transporter
CLQ46_RS21395	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
CLQ46_RS21435	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
CLQ46_RS21440	COG2885	chlorophyll binding
CLQ46_RS21450	COG3064	Membrane
CLQ46_RS21455	COG0848	biopolymer transport protein
CLQ46_RS21460	COG0811	peptide transport
CLQ46_RS21465	COG0824	Thioesterase
CLQ46_RS21470	COG3790	cyd operon protein YbgE
CLQ46_RS21475	COG4890	Cyd operon protein YbgT
CLQ46_RS21480	COG1294	oxidase, subunit
CLQ46_RS21485	COG1271	oxidase subunit
CLQ46_RS21495	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
CLQ46_RS21505	COG0508	dehydrogenase complex catalyzes the overall conversion of
CLQ46_RS21510	COG0567	Dehydrogenase, E1 component
CLQ46_RS21515	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CLQ46_RS21520	COG1053	succinate dehydrogenase
CLQ46_RS21525	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
CLQ46_RS21530	COG2009	succinate dehydrogenase
CLQ46_RS21575	COG1984	allophanate hydrolase subunit 2
CLQ46_RS21580	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
CLQ46_RS21595	COG0415	Belongs to the DNA photolyase family
CLQ46_RS21625	COG2205	protein histidine kinase activity
CLQ46_RS21630	COG0745	RESPONSE REGULATOR receiver
CLQ46_RS21640	COG0033	Phosphoglucomutase
CLQ46_RS21650	COG0596	Alpha beta hydrolase
CLQ46_RS21665	COG0735	belongs to the Fur family
CLQ46_RS21710	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
CLQ46_RS21715	COG1846	Transcriptional regulator
CLQ46_RS21715	COG1940	carbohydrate kinase activity
CLQ46_RS21720	COG0647	UMP catabolic process
CLQ46_RS21725	COG0367	asparagine synthase
CLQ46_RS21770	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CLQ46_RS21780	COG1702	phosphate starvation-inducible protein PhoH
CLQ46_RS21790	COG4535	Mg2 and Co2 transporter CorC
CLQ46_RS21805	COG0765	amino acid transport
CLQ46_RS21810	COG0765	amino acid transport
CLQ46_RS21815	COG1126	abc transporter atp-binding protein
CLQ46_RS21830	COG2888	peptidyl-tyrosine sulfation
CLQ46_RS21845	COG1466	dna polymerase III delta subunit
CLQ46_RS21865	COG0799	negative regulation of ribosome biogenesis
CLQ46_RS21875	COG0768	penicillin binding
CLQ46_RS21880	COG0772	Belongs to the SEDS family
CLQ46_RS21885	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
CLQ46_RS21890	COG1686	Belongs to the peptidase S11 family
CLQ46_RS21905	COG0583	DNA-binding transcription factor activity
CLQ46_RS21920	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CLQ46_RS21945	COG3069	C4-dicarboxylate transmembrane transporter activity
CLQ46_RS21950	COG3719	Belongs to the RNase T2 family
CLQ46_RS21955	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CLQ46_RS21975	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CLQ46_RS21980	COG0583	DNA-binding transcription factor activity
CLQ46_RS21985	COG3969	phosphoadenosine phosphosulfate
CLQ46_RS21990	COG1475	DNA binding
CLQ46_RS21995	COG0436	Aminotransferase
CLQ46_RS22020	COG1129	ABC transporter
CLQ46_RS22025	COG1172	Belongs to the binding-protein-dependent transport system permease family
CLQ46_RS22030	COG1172	Belongs to the binding-protein-dependent transport system permease family
CLQ46_RS22040	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CLQ46_RS22055	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
CLQ46_RS22065	COG0402	S-adenosylhomocysteine deaminase activity
CLQ46_RS22075	COG0483	inositol monophosphate 1-phosphatase activity
CLQ46_RS22080	COG2271	Major facilitator Superfamily
CLQ46_RS22110	COG1172	Belongs to the binding-protein-dependent transport system permease family
CLQ46_RS22115	COG1129	ABC transporter
CLQ46_RS22120	COG0371	Dehydrogenase
CLQ46_RS22125	COG1028	Short-chain dehydrogenase reductase Sdr
CLQ46_RS22140	COG2879	small protein
CLQ46_RS22165	COG1028	Short-chain dehydrogenase reductase Sdr
CLQ46_RS22170	COG3433	isochorismatase activity
CLQ46_RS22170	COG1535	isochorismatase
CLQ46_RS22175	COG1021	2,3-dihydroxybenzoate-AMP ligase
CLQ46_RS22180	COG1169	isochorismate synthase
CLQ46_RS22185	COG4592	Periplasmic binding protein
CLQ46_RS22195	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CLQ46_RS22200	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CLQ46_RS22205	COG1120	ATPase activity
CLQ46_RS22210	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CLQ46_RS22210	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
CLQ46_RS22215	COG3251	PFAM MbtH domain protein
CLQ46_RS22220	COG2382	esterase
CLQ46_RS22225	COG4771	TonB-dependent receptor
CLQ46_RS22230	COG2977	Belongs to the P-Pant transferase superfamily
CLQ46_RS22235	COG3958	Transketolase
CLQ46_RS22240	COG3959	Transketolase, thiamine diphosphate binding domain
CLQ46_RS22250	COG2390	Transcriptional regulator
CLQ46_RS22255	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CLQ46_RS22260	COG1879	ABC-type sugar transport system periplasmic component
CLQ46_RS22270	COG1129	ABC transporter
CLQ46_RS22275	COG1172	Belongs to the binding-protein-dependent transport system permease family
CLQ46_RS22285	COG1028	Short-chain dehydrogenase reductase Sdr
CLQ46_RS22295	COG0583	DNA-binding transcription factor activity
CLQ46_RS22300	COG0668	transmembrane transport
CLQ46_RS22310	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CLQ46_RS22340	COG0747	negative chemotaxis
CLQ46_RS22345	COG0601	transmembrane transport
CLQ46_RS22350	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CLQ46_RS22355	COG0444	Belongs to the ABC transporter superfamily
CLQ46_RS22360	COG4608	Belongs to the ABC transporter superfamily
CLQ46_RS22370	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CLQ46_RS22375	COG4221	oxidoreductase activity
CLQ46_RS22385	COG4215	(ABC) transporter
CLQ46_RS22390	COG0765	amino acid transport
CLQ46_RS22395	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
CLQ46_RS22410	COG0697	spore germination
CLQ46_RS22420	COG3698	Phosphodiester glycosidase
CLQ46_RS22470	COG2315	Protein conserved in bacteria
CLQ46_RS22475	COG0778	Nitroreductase
CLQ46_RS22485	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CLQ46_RS22495	COG3716	PTS system mannose fructose sorbose family IID component
CLQ46_RS22500	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CLQ46_RS22505	COG2222	sugar isomerase
CLQ46_RS22510	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
CLQ46_RS22510	COG3933	PFAM sigma-54 factor interaction domain-containing protein
CLQ46_RS22530	COG0477	Major facilitator Superfamily
CLQ46_RS22535	COG0668	transmembrane transport
CLQ46_RS22565	COG3188	usher protein
CLQ46_RS22580	COG2771	luxR family
CLQ46_RS22590	COG0673	inositol 2-dehydrogenase activity
CLQ46_RS22600	COG2211	Major facilitator Superfamily
CLQ46_RS22605	COG1113	amino acid transport
CLQ46_RS22620	COG1012	belongs to the aldehyde dehydrogenase family
CLQ46_RS22625	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CLQ46_RS22635	COG0531	amino acid
CLQ46_RS22685	COG0667	Aldo Keto reductase
CLQ46_RS22690	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CLQ46_RS22695	COG1473	amidohydrolase
CLQ46_RS22715	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CLQ46_RS22720	COG1120	ATPase activity
CLQ46_RS22725	COG1566	PFAM secretion protein HlyD family protein
CLQ46_RS22770	COG1172	Belongs to the binding-protein-dependent transport system permease family
CLQ46_RS22775	COG1129	ABC transporter
CLQ46_RS22790	COG0673	inositol 2-dehydrogenase activity
CLQ46_RS22820	COG3104	oligopeptide transport
CLQ46_RS22825	COG1982	Orn Lys Arg decarboxylase major
CLQ46_RS22830	COG0531	amino acid
CLQ46_RS22835	COG3710	Transcriptional regulator
CLQ46_RS22845	COG1560	Kdo2-lipid A biosynthetic process
CLQ46_RS22860	COG3188	usher protein
CLQ46_RS22865	COG3121	Chaperone
CLQ46_RS22870	COG3539	Fimbrial protein
CLQ46_RS22930	COG2501	S4 domain
CLQ46_RS22940	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CLQ46_RS22960	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
CLQ46_RS22965	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
CLQ46_RS22980	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
CLQ46_RS22985	COG4181	ATPase activity
CLQ46_RS22990	COG2755	lipolytic protein G-D-S-L family
CLQ46_RS22995	COG0300	oxidoreductase activity
CLQ46_RS23000	COG3118	belongs to the thioredoxin family
CLQ46_RS23010	COG0390	transport system, permease component
CLQ46_RS23015	COG4619	ABC transporter
CLQ46_RS23020	COG0330	HflC and HflK could
CLQ46_RS23025	COG1585	Membrane protein implicated in regulation of membrane protease activity
CLQ46_RS23040	COG3735	TraB family
CLQ46_RS23045	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CLQ46_RS23055	COG2223	nitrite transmembrane transporter activity
CLQ46_RS23060	COG4651	solute:proton antiporter activity
CLQ46_RS23060	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CLQ46_RS23065	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CLQ46_RS23110	COG2832	Protein of unknown function (DUF454)
CLQ46_RS23115	COG3923	Primosomal replication protein n
CLQ46_RS23125	COG5464	transposase or invertase
CLQ46_RS23130	COG1196	nuclear chromosome segregation
CLQ46_RS23130	COG3264	Mechanosensitive ion channel
CLQ46_RS23150	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CLQ46_RS23155	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CLQ46_RS23170	COG0110	maltose O-acetyltransferase activity
CLQ46_RS23215	COG1874	Beta-galactosidase
CLQ46_RS23220	COG3867	Arabinogalactan endo-beta-1,4-galactanase
CLQ46_RS23225	COG3833	ABC-type maltose transport systems, permease component
CLQ46_RS23230	COG1175	transmembrane transport
CLQ46_RS23235	COG2182	Extracellular solute-binding protein
CLQ46_RS23245	COG4943	cyclic-guanylate-specific phosphodiesterase activity
CLQ46_RS23260	COG2364	Membrane
CLQ46_RS23290	COG3695	enzyme binding
CLQ46_RS23295	COG3126	Type III secretion system lipoprotein chaperone (YscW)
CLQ46_RS23300	COG1946	Acyl-CoA thioesterase
CLQ46_RS23305	COG0004	ammonium transporteR
CLQ46_RS23310	COG0347	Belongs to the P(II) protein family
CLQ46_RS23315	COG1132	(ABC) transporter
CLQ46_RS23320	COG1132	(ABC) transporter
CLQ46_RS23325	COG1522	sequence-specific DNA binding
CLQ46_RS23340	COG4533	DNA binding
CLQ46_RS23350	COG0824	Thioesterase
CLQ46_RS23355	COG1555	photosystem II stabilization
CLQ46_RS23360	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CLQ46_RS23365	COG0776	regulation of translation
CLQ46_RS23370	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
CLQ46_RS23400	COG0271	Belongs to the BolA IbaG family
CLQ46_RS23405	COG3056	Lipoprotein
CLQ46_RS23410	COG2223	nitrite transmembrane transporter activity
CLQ46_RS23415	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
CLQ46_RS23420	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CLQ46_RS23425	COG1845	cytochrome c oxidase, subunit III
CLQ46_RS23430	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
CLQ46_RS23445	COG1414	Transcriptional regulator
CLQ46_RS23450	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CLQ46_RS23455	COG1053	succinate dehydrogenase
CLQ46_RS23465	COG1053	succinate dehydrogenase
CLQ46_RS23480	COG0673	inositol 2-dehydrogenase activity
CLQ46_RS23485	COG2814	Major facilitator Superfamily
CLQ46_RS23495	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CLQ46_RS23500	COG0693	protein deglycase activity
CLQ46_RS23520	COG0142	geranyltranstransferase activity
CLQ46_RS23530	COG0667	Aldo Keto reductase
CLQ46_RS23535	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
CLQ46_RS23555	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CLQ46_RS23555	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CLQ46_RS23565	COG4238	major outer membrane lipoprotein
CLQ46_RS23585	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CLQ46_RS23590	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CLQ46_RS23595	COG1862	Preprotein translocase
CLQ46_RS23615	COG0450	alkyl hydroperoxide reductase
CLQ46_RS23620	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CLQ46_RS23635	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CLQ46_RS23645	COG1228	amidohydrolase
CLQ46_RS23655	COG1335	isochorismatase
CLQ46_RS23660	COG0583	DNA-binding transcription factor activity
CLQ46_RS23665	COG0366	Alpha amylase catalytic
CLQ46_RS23690	COG0420	3'-5' exonuclease activity
CLQ46_RS23695	COG0419	ATPase involved in DNA repair
CLQ46_RS23700	COG1940	carbohydrate kinase activity
CLQ46_RS23715	COG4126	flavin adenine dinucleotide binding
CLQ46_RS23725	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
CLQ46_RS23730	COG3416	Protein conserved in bacteria
CLQ46_RS23740	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CLQ46_RS23750	COG1785	Belongs to the alkaline phosphatase family
CLQ46_RS23790	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
CLQ46_RS23795	COG1335	isochorismatase
CLQ46_RS23800	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CLQ46_RS23805	COG0113	porphobilinogen synthase activity
CLQ46_RS23815	COG2175	clavaminate synthase activity
CLQ46_RS23820	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CLQ46_RS23825	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
CLQ46_RS23830	COG4521	taurine ABC transporter
CLQ46_RS23835	COG2040	homocysteine
CLQ46_RS23840	COG0833	amino acid
CLQ46_RS23850	COG4303	Ethanolamine ammonia lyase large subunit
CLQ46_RS23855	COG4302	ethanolamine ammonia-lyase activity
CLQ46_RS23890	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CLQ46_RS23895	COG1126	abc transporter atp-binding protein
CLQ46_RS23900	COG0765	amino acid transport
CLQ46_RS23905	COG0765	amino acid transport
CLQ46_RS23920	COG3188	usher protein
CLQ46_RS23945	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
CLQ46_RS23955	COG3639	organic phosphonate transmembrane transporter activity
CLQ46_RS23985	COG0791	NLP P60 protein
CLQ46_RS24010	COG0582	viral genome integration into host DNA
CLQ46_RS24015	COG1192	Involved in chromosome partitioning
CLQ46_RS24075	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
CLQ46_RS24080	COG0022	dehydrogenase e1 component
CLQ46_RS24085	COG0508	dehydrogenase complex catalyzes the overall conversion of
CLQ46_RS24090	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CLQ46_RS24115	COG1070	Carbohydrate kinase
CLQ46_RS24120	COG1028	Short-chain dehydrogenase reductase Sdr
CLQ46_RS24125	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CLQ46_RS24130	COG3775	system Galactitol-specific IIC component
CLQ46_RS24135	COG0625	glutathione transferase activity
CLQ46_RS24140	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
CLQ46_RS24160	COG0579	oxidoreductase
CLQ46_RS24165	COG1012	belongs to the aldehyde dehydrogenase family
CLQ46_RS24170	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CLQ46_RS24175	COG1113	amino acid transport
CLQ46_RS24180	COG1802	Transcriptional regulator
CLQ46_RS24200	COG2195	Cleaves the N-terminal amino acid of tripeptides
CLQ46_RS24205	COG0454	-acetyltransferase
CLQ46_RS24220	COG2991	Protein conserved in bacteria
CLQ46_RS24235	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
CLQ46_RS24240	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
CLQ46_RS24260	COG3034	peptidoglycan biosynthetic process
CLQ46_RS24265	COG0121	glutamine amidotransferase
CLQ46_RS24275	COG1960	acyl-CoA dehydrogenase activity
CLQ46_RS24280	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CLQ46_RS24290	COG0583	DNA-binding transcription factor activity
CLQ46_RS24305	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CLQ46_RS24315	COG2226	methyltransferase
CLQ46_RS24325	COG0741	lytic transglycosylase activity
CLQ46_RS24325	COG1388	LysM domain
CLQ46_RS24330	COG2226	methyltransferase
CLQ46_RS24340	COG2814	Major facilitator Superfamily
CLQ46_RS24345	COG0583	DNA-binding transcription factor activity
CLQ46_RS24350	COG0656	L-ascorbic acid biosynthetic process
CLQ46_RS24390	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
CLQ46_RS24400	COG2011	ABC-type metal ion transport system permease component
CLQ46_RS24405	COG1464	Belongs to the NlpA lipoprotein family
CLQ46_RS24415	COG1720	tRNA m6t6A37 methyltransferase activity
CLQ46_RS24425	COG0791	NLP P60 protein
CLQ46_RS24430	COG3015	lipoprotein NlpE involved in copper resistance
CLQ46_RS24435	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
CLQ46_RS24450	COG4568	rho-dependent transcription termination
CLQ46_RS24460	COG0346	lactoylglutathione lyase activity
CLQ46_RS24465	COG1982	Orn Lys Arg decarboxylase major
CLQ46_RS24505	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
CLQ46_RS24515	COG0750	zinc metalloprotease
CLQ46_RS24520	COG0575	Belongs to the CDS family
CLQ46_RS24535	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
CLQ46_RS24560	COG0024	Methionine aminopeptidase
CLQ46_RS24565	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
CLQ46_RS24580	COG3835	regulator
CLQ46_RS24585	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CLQ46_RS24605	COG2860	membrane
CLQ46_RS24625	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CLQ46_RS24630	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CLQ46_RS24635	COG1120	ATPase activity
CLQ46_RS24645	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CLQ46_RS24735	COG1643	Atp-dependent helicase
CLQ46_RS24740	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
CLQ46_RS24760	COG0617	tRNA 3'-terminal CCA addition
CLQ46_RS24765	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CLQ46_RS24785	COG0726	polysaccharide deacetylase
CLQ46_RS24790	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
CLQ46_RS24795	COG0842	Transport permease protein
CLQ46_RS24800	COG1131	(ABC) transporter
CLQ46_RS24805	COG0288	reversible hydration of carbon dioxide
CLQ46_RS24815	COG4993	Dehydrogenase
CLQ46_RS24820	COG2132	Multicopper oxidase
CLQ46_RS24875	COG3064	Membrane
CLQ46_RS24890	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CLQ46_RS24895	COG0508	dehydrogenase complex catalyzes the overall conversion of
CLQ46_RS24900	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
CLQ46_RS24905	COG2186	Transcriptional regulator
CLQ46_RS24910	COG1113	amino acid transport
CLQ46_RS24915	COG2211	Major facilitator Superfamily
CLQ46_RS24920	COG3940	Belongs to the glycosyl hydrolase 43 family
CLQ46_RS24925	COG3725	Membrane protein required for beta-lactamase induction
CLQ46_RS24930	COG3023	N-Acetylmuramoyl-L-alanine amidase
CLQ46_RS24940	COG4969	Belongs to the N-Me-Phe pilin family
CLQ46_RS24945	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CLQ46_RS24950	COG1459	type II secretion system
CLQ46_RS24975	COG0494	nUDIX hydrolase
CLQ46_RS24995	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CLQ46_RS25000	COG0849	cell division
CLQ46_RS25025	COG0772	Belongs to the SEDS family
CLQ46_RS25040	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
CLQ46_RS25045	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CLQ46_RS25050	COG0768	penicillin binding
CLQ46_RS25075	COG1609	Transcriptional regulator
CLQ46_RS25085	COG0028	Belongs to the TPP enzyme family
CLQ46_RS25135	COG0738	Major facilitator superfamily
CLQ46_RS25145	COG0583	DNA-binding transcription factor activity
CLQ46_RS25150	COG2271	Major facilitator Superfamily
CLQ46_RS25155	COG2814	Major facilitator Superfamily
CLQ46_RS25175	COG1178	ABC-type Fe3 transport system permease component
CLQ46_RS25185	COG0586	Pfam SNARE associated Golgi protein
CLQ46_RS25220	COG0417	DNA replication proofreading
CLQ46_RS25225	COG0235	Class ii aldolase
CLQ46_RS25255	COG0564	pseudouridine synthase activity
CLQ46_RS25270	COG3493	citrate carrier protein
CLQ46_RS25285	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
CLQ46_RS25290	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
CLQ46_RS25300	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
CLQ46_RS25355	COG0505	Belongs to the CarA family
CLQ46_RS25425	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CLQ46_RS25450	COG1047	Peptidyl-prolyl cis-trans
CLQ46_RS25465	COG0196	riboflavin kinase activity
CLQ46_RS25485	COG0583	DNA-binding transcription factor activity
CLQ46_RS25510	COG4735	regulation of single-species biofilm formation
CLQ46_RS25515	COG1584	GPR1 FUN34 yaaH family protein
CLQ46_RS25520	COG0477	Major facilitator Superfamily
CLQ46_RS25525	COG0521	Mo-molybdopterin cofactor biosynthetic process
CLQ46_RS25530	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CLQ46_RS25535	COG1115	amino acid carrier protein
CLQ46_RS25550	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
CLQ46_RS25560	COG0460	homoserine dehydrogenase
CLQ46_RS25560	COG0527	aspartate kinase activity
CLQ46_RS25570	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
CLQ46_RS25585	COG0745	RESPONSE REGULATOR receiver
CLQ46_RS25590	COG4452	Inner membrane protein CreD
CLQ46_RS25595	COG2205	protein histidine kinase activity
CLQ46_RS25600	COG0745	RESPONSE REGULATOR receiver
CLQ46_RS25605	COG3045	CreA protein
CLQ46_RS25610	COG2207	Transcriptional regulator
CLQ46_RS25610	COG3708	Transcriptional regulator
CLQ46_RS25630	COG0741	lytic transglycosylase activity
CLQ46_RS25640	COG0488	(ABC) transporter
CLQ46_RS25650	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
CLQ46_RS25655	COG0560	Phosphoserine phosphatase
CLQ46_RS25665	COG3726	membrane protein affecting hemolysin expression
CLQ46_RS25695	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CLQ46_RS25700	COG0084	hydrolase, TatD family'
CLQ46_RS25705	COG4667	esterase of the alpha-beta hydrolase superfamily
CLQ46_RS25715	COG2823	Periplasmic or secreted lipoprotein
CLQ46_RS25725	COG1011	Hydrolase
CLQ46_RS25730	COG0456	acetyltransferase
CLQ46_RS25735	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
CLQ46_RS25765	COG3706	GGDEF domain
CLQ46_RS25770	COG4114	ferric iron reductase
CLQ46_RS25775	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CLQ46_RS25775	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CLQ46_RS25780	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CLQ46_RS25785	COG2197	response regulator
CLQ46_RS25790	COG2197	response regulator
CLQ46_RS25810	COG2966	Psort location CytoplasmicMembrane, score
CLQ46_RS25825	COG1484	DNA-dependent DNA replication
CLQ46_RS25840	COG5464	transposase or invertase
CLQ46_RS25850	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CLQ46_RS25855	COG3716	PTS system mannose fructose sorbose family IID component
CLQ46_RS25860	COG3715	PTS system
CLQ46_RS25875	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
CLQ46_RS25875	COG3933	PFAM sigma-54 factor interaction domain-containing protein
CLQ46_RS25885	COG1063	alcohol dehydrogenase
CLQ46_RS25890	COG1802	Transcriptional regulator
CLQ46_RS25895	COG2271	Major facilitator Superfamily
CLQ46_RS25900	COG0456	acetyltransferase
CLQ46_RS25900	COG1214	PFAM Peptidase M22, glycoprotease
CLQ46_RS25910	COG1737	Transcriptional regulator
CLQ46_RS25915	COG0800	Aldolase
CLQ46_RS25920	COG3734	2-keto-3-deoxy-galactonokinase
CLQ46_RS25935	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
CLQ46_RS25965	COG1846	Transcriptional regulator
CLQ46_RS25975	COG0179	Fumarylacetoacetate (FAA) hydrolase
CLQ46_RS25985	COG1012	belongs to the aldehyde dehydrogenase family
CLQ46_RS25990	COG3384	dioxygenase
CLQ46_RS26000	COG3971	2-oxopent-4-enoate hydratase activity
CLQ46_RS26020	COG2368	4-hydroxyphenylacetate
CLQ46_RS26025	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CLQ46_RS26040	COG1966	Carbon starvation protein
CLQ46_RS26045	COG2879	small protein
CLQ46_RS26050	COG0523	cobalamin synthesis protein
CLQ46_RS26060	COG1012	belongs to the aldehyde dehydrogenase family
CLQ46_RS26065	COG5464	transposase or invertase
CLQ46_RS26070	COG2207	Transcriptional regulator
CLQ46_RS26070	COG1917	Cupin 2, conserved barrel domain protein
CLQ46_RS26080	COG2733	membrane
CLQ46_RS26095	COG1775	2-hydroxyglutaryl-CoA dehydratase, D-component
CLQ46_RS26100	COG1924	4 iron, 4 sulfur cluster binding
CLQ46_RS26115	COG1566	PFAM secretion protein HlyD family protein
CLQ46_RS26125	COG5457	Domain of unknown function (DUF1127)
CLQ46_RS26130	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CLQ46_RS26140	COG0583	DNA-binding transcription factor activity
CLQ46_RS26145	COG2249	NAD(P)H dehydrogenase (quinone) activity
CLQ46_RS26155	COG1172	Belongs to the binding-protein-dependent transport system permease family
CLQ46_RS26160	COG1129	ABC transporter
CLQ46_RS26165	COG1879	ABC-type sugar transport system periplasmic component
CLQ46_RS26175	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CLQ46_RS26180	COG1129	ABC transporter
CLQ46_RS26180	COG0842	Transport permease protein
CLQ46_RS26185	COG0842	Transport permease protein
CLQ46_RS26220	COG2850	peptidyl-arginine hydroxylation
CLQ46_RS26235	COG5002	protein histidine kinase activity
CLQ46_RS26240	COG0745	RESPONSE REGULATOR receiver
CLQ46_RS26250	COG1538	Outer membrane efflux protein
CLQ46_RS26255	COG5569	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CLQ46_RS26260	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CLQ46_RS26265	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CLQ46_RS26275	COG3040	lipid binding
CLQ46_RS26280	COG0789	Transcriptional regulator
CLQ46_RS26290	COG0300	oxidoreductase activity
CLQ46_RS26305	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CLQ46_RS26325	COG3272	Protein of unknown function (DUF1722)
CLQ46_RS26330	COG4580	involved in the transport of maltose and maltodextrins
CLQ46_RS26340	COG2211	Major facilitator Superfamily
CLQ46_RS26345	COG3507	Belongs to the glycosyl hydrolase 43 family
CLQ46_RS26375	COG3039	Transposase
CLQ46_RS26385	COG0582	viral genome integration into host DNA
CLQ46_RS26400	COG0288	reversible hydration of carbon dioxide
CLQ46_RS26405	COG0659	secondary active sulfate transmembrane transporter activity
CLQ46_RS26410	COG1064	alcohol dehydrogenase
CLQ46_RS26415	COG1175	transmembrane transport
CLQ46_RS26420	COG0395	ABC-type sugar transport system, permease component
CLQ46_RS26425	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
CLQ46_RS26430	COG3842	ATPase activity
CLQ46_RS26435	COG1653	transport
CLQ46_RS26445	COG1082	Xylose isomerase domain protein TIM barrel
CLQ46_RS26455	COG3962	Belongs to the TPP enzyme family
CLQ46_RS26460	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CLQ46_RS26465	COG1737	Transcriptional regulator
CLQ46_RS26465	COG0837	glucose binding
CLQ46_RS26500	COG3718	enzyme involved in inositol metabolism
CLQ46_RS26515	COG0433	COG0433 Predicted ATPase
CLQ46_RS26520	COG0795	lipopolysaccharide-transporting ATPase activity
CLQ46_RS26525	COG0795	lipopolysaccharide-transporting ATPase activity
CLQ46_RS26540	COG2927	DNA polymerase III (CHI subunit)
CLQ46_RS26545	COG0525	valine-tRNA ligase activity
CLQ46_RS26570	COG2188	Transcriptional regulator
CLQ46_RS26575	COG1288	antiporter activity
CLQ46_RS26580	COG1228	amidohydrolase
CLQ46_RS26600	COG2222	sugar isomerase
CLQ46_RS26605	COG2731	YhcH YjgK YiaL family protein
CLQ46_RS26650	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CLQ46_RS26650	COG1263	PTS System
CLQ46_RS26655	COG0366	Alpha amylase catalytic
CLQ46_RS26660	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CLQ46_RS26665	COG1486	melibiose metabolic process
CLQ46_RS26685	COG0602	queuosine metabolic process
CLQ46_RS26690	COG2026	Addiction module toxin, RelE StbE family
CLQ46_RS26695	COG3077	Addiction module antitoxin, RelB DinJ family
CLQ46_RS26700	COG3711	transcriptional antiterminator
CLQ46_RS26700	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CLQ46_RS26705	COG2706	6-phosphogluconolactonase activity
CLQ46_RS26720	COG3964	amidohydrolase
CLQ46_RS26755	COG0312	modulator of DNA gyrase
CLQ46_RS26775	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CLQ46_RS26785	COG1172	Belongs to the binding-protein-dependent transport system permease family
CLQ46_RS26790	COG1172	Belongs to the binding-protein-dependent transport system permease family
CLQ46_RS26795	COG1129	ABC transporter
CLQ46_RS26800	COG1879	ABC-type sugar transport system periplasmic component
CLQ46_RS26820	COG2105	PFAM AIG2 family protein
CLQ46_RS26825	COG2911	Protein conserved in bacteria
CLQ46_RS26830	COG0729	surface antigen
CLQ46_RS26840	COG1253	flavin adenine dinucleotide binding
CLQ46_RS26855	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
CLQ46_RS26870	COG1733	regulation of RNA biosynthetic process
CLQ46_RS26875	COG0702	epimerase
CLQ46_RS26885	COG0697	spore germination
CLQ46_RS26895	COG1113	amino acid transport
CLQ46_RS26900	COG0545	Peptidyl-prolyl cis-trans isomerase
CLQ46_RS26905	COG3061	Opacity-associated protein A
CLQ46_RS26915	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
CLQ46_RS26920	COG2965	DNA replication, synthesis of RNA primer
CLQ46_RS26980	COG1073	alpha beta
CLQ46_RS26985	COG3650	response to hydrogen peroxide
CLQ46_RS26995	COG1960	acyl-CoA dehydrogenase activity
CLQ46_RS27000	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CLQ46_RS27005	COG0557	exoribonuclease II activity
CLQ46_RS27020	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
CLQ46_RS27030	COG0330	HflC and HflK could
CLQ46_RS27035	COG0330	HflC and HflK could
CLQ46_RS27040	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CLQ46_RS27060	COG0860	N-Acetylmuramoyl-L-alanine amidase
CLQ46_RS27065	COG0802	atpase or kinase
CLQ46_RS27070	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
CLQ46_RS27070	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
CLQ46_RS27075	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
CLQ46_RS27125	COG0629	single-stranded DNA binding
CLQ46_RS27135	COG0270	DNA (cytosine-5-)-methyltransferase activity
CLQ46_RS27325	COG2003	Belongs to the UPF0758 family
CLQ46_RS27470	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
CLQ46_RS27470	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CLQ46_RS27475	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CLQ46_RS27480	COG1252	NADH dehydrogenase
CLQ46_RS27485	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
CLQ46_RS27550	COG4372	Transposase
CLQ46_RS27575	COG0583	DNA-binding transcription factor activity
CLQ46_RS27590	COG0583	DNA-binding transcription factor activity
CLQ46_RS27605	COG2837	iron assimilation
CLQ46_RS27610	COG0582	viral genome integration into host DNA
CLQ46_RS27635	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CLQ46_RS27660	COG3264	Mechanosensitive ion channel
CLQ46_RS27660	COG1511	domain protein
CLQ46_RS27675	COG1053	succinate dehydrogenase
CLQ46_RS27680	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CLQ46_RS27700	COG2076	Multidrug Resistance protein
CLQ46_RS27705	COG5510	response to toxic substance
CLQ46_RS27720	COG1509	lysine 2,3-aminomutase activity
CLQ46_RS27790	COG0531	amino acid
CLQ46_RS27795	COG3030	protein affecting phage T7 exclusion by the F plasmid
CLQ46_RS27805	COG1027	Aspartate ammonia-lyase
CLQ46_RS27810	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
CLQ46_RS27825	COG1309	transcriptional regulator
CLQ46_RS27855	COG0457	Tetratricopeptide repeat
CLQ46_RS27860	COG1649	PFAM Uncharacterised BCR, COG1649
CLQ46_RS27860	COG0726	polysaccharide deacetylase
CLQ46_RS27865	COG1215	transferase activity, transferring glycosyl groups
CLQ46_RS27885	COG0861	Integral membrane protein TerC family
CLQ46_RS27920	COG1486	melibiose metabolic process
CLQ46_RS27930	COG2169	Transcriptional regulator
CLQ46_RS27945	COG2824	Alkylphosphonate utilization operon protein PhnA
CLQ46_RS27950	COG2764	glyoxalase bleomycin resistance protein dioxygenase
CLQ46_RS27955	COG2188	Transcriptional regulator
CLQ46_RS27960	COG3624	Phosphonate C-P lyase system protein PhnG
CLQ46_RS27965	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
CLQ46_RS27970	COG3626	phosphonate metabolism
CLQ46_RS27975	COG3627	carbon phosphorus lyase activity
CLQ46_RS27980	COG4107	phosphonate C-P lyase system protein PhnK
CLQ46_RS27985	COG4778	phosphonate C-P lyase system protein PhnL
CLQ46_RS27990	COG3454	Phosphonate metabolism
CLQ46_RS28000	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
CLQ46_RS28010	COG4191	Histidine kinase
CLQ46_RS28010	COG0784	Response regulator, receiver
CLQ46_RS28015	COG1129	ABC transporter
CLQ46_RS28020	COG1172	Belongs to the binding-protein-dependent transport system permease family
CLQ46_RS28055	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
CLQ46_RS28060	COG1301	dicarboxylic acid transport
CLQ46_RS28070	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CLQ46_RS28080	COG3162	membrane
CLQ46_RS28110	COG3539	Fimbrial protein
CLQ46_RS28115	COG1346	cytolysis
CLQ46_RS28120	COG1380	Effector of murein hydrolase LrgA
CLQ46_RS28125	COG0583	DNA-binding transcription factor activity
CLQ46_RS28130	COG0025	NhaP-type Na H and K H
CLQ46_RS28135	COG2252	PERMEase
CLQ46_RS28140	COG0625	glutathione transferase activity
CLQ46_RS28145	COG0789	Transcriptional regulator
CLQ46_RS28155	COG4943	cyclic-guanylate-specific phosphodiesterase activity
CLQ46_RS28190	COG1234	tRNA 3'-trailer cleavage
CLQ46_RS28195	COG1609	Transcriptional regulator
CLQ46_RS28200	COG0483	inositol monophosphate 1-phosphatase activity
CLQ46_RS28215	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CLQ46_RS28235	COG4771	TonB-dependent receptor
CLQ46_RS28240	COG0741	lytic transglycosylase activity
CLQ46_RS28260	COG2315	Protein conserved in bacteria
CLQ46_RS28265	COG0432	Pfam Uncharacterised protein family UPF0047
CLQ46_RS28280	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CLQ46_RS28285	COG0305	Participates in initiation and elongation during chromosome replication
CLQ46_RS28300	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CLQ46_RS28310	COG0735	belongs to the Fur family
CLQ46_RS28315	COG3237	CsbD-like
CLQ46_RS28320	COG0534	Mate efflux family protein
CLQ46_RS28330	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
CLQ46_RS28405	COG0251	oxidation-reduction process
CLQ46_RS28415	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
CLQ46_RS28435	COG0527	aspartate kinase activity
CLQ46_RS28490	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CLQ46_RS28520	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
CLQ46_RS28530	COG0456	acetyltransferase
CLQ46_RS28570	COG0151	Belongs to the GarS family
CLQ46_RS28580	COG4191	Histidine kinase
CLQ46_RS28585	COG3678	ATP-independent chaperone mediated protein folding
CLQ46_RS28620	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
CLQ46_RS28635	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CLQ46_RS28640	COG2104	thiamine diphosphate biosynthetic process
CLQ46_RS28660	COG3706	GGDEF domain
CLQ46_RS28670	COG1447	Phosphotransferase system cellobiose-specific component IIA
CLQ46_RS28675	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
CLQ46_RS28715	COG0250	Participates in transcription elongation, termination and antitermination
CLQ46_RS28765	COG0812	UDP-N-acetylmuramate dehydrogenase activity
CLQ46_RS28800	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
CLQ46_RS28810	COG1739	Uncharacterized protein family UPF0029
CLQ46_RS28855	COG0805	protein transport
CLQ46_RS28875	COG3165	ubiquinone biosynthetic process from chorismate
CLQ46_RS28905	COG0583	DNA-binding transcription factor activity
CLQ46_RS28910	COG0697	spore germination
CLQ46_RS28915	COG0561	phosphatase activity
CLQ46_RS28920	COG2267	carboxylic ester hydrolase activity
CLQ46_RS28925	COG1280	lysine exporter protein (LysE YggA)
CLQ46_RS28935	COG1280	lysine exporter protein (LysE YggA)
CLQ46_RS28970	COG0210	DNA helicase
CLQ46_RS28975	COG1011	Hydrolase
CLQ46_RS29005	COG3072	Adenylate cyclase
CLQ46_RS29020	COG2959	enzyme of heme biosynthesis
CLQ46_RS29025	COG3071	HemY protein
CLQ46_RS29070	COG2244	polysaccharide biosynthetic process
CLQ46_RS29075	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CLQ46_RS29080	COG0456	acetyltransferase
CLQ46_RS29085	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
CLQ46_RS29090	COG1088	dTDP-glucose 4,6-dehydratase activity
CLQ46_RS29095	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
CLQ46_RS29100	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
CLQ46_RS29110	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CLQ46_RS29115	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
CLQ46_RS29125	COG3118	belongs to the thioredoxin family
CLQ46_RS29155	COG1811	Na channel or pump
CLQ46_RS29165	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CLQ46_RS29170	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CLQ46_RS29180	COG0583	DNA-binding transcription factor activity
CLQ46_RS29185	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CLQ46_RS29200	COG3978	acetolactate synthase activity
CLQ46_RS29220	COG3085	chromosome segregation
CLQ46_RS29295	COG0583	DNA-binding transcription factor activity
CLQ46_RS29320	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
CLQ46_RS29335	COG3443	Belongs to the bacterial solute-binding protein 9 family
CLQ46_RS29340	COG2207	Transcriptional regulator
CLQ46_RS29350	COG0371	Dehydrogenase
CLQ46_RS29355	COG0697	spore germination
CLQ46_RS29365	COG0583	DNA-binding transcription factor activity
CLQ46_RS29375	COG0737	Belongs to the 5'-nucleotidase family
CLQ46_RS29385	COG0527	aspartate kinase activity
CLQ46_RS29385	COG0460	homoserine dehydrogenase
CLQ46_RS29390	COG0626	cystathionine gamma-synthase activity
CLQ46_RS29405	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CLQ46_RS29410	COG1609	Transcriptional regulator
CLQ46_RS29415	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
CLQ46_RS29430	COG1575	Belongs to the MenA family. Type 1 subfamily
CLQ46_RS29450	COG3678	ATP-independent chaperone mediated protein folding
CLQ46_RS29455	COG0745	RESPONSE REGULATOR receiver
CLQ46_RS29460	COG2205	protein histidine kinase activity
CLQ46_RS29465	COG2258	MOSC domain
CLQ46_RS29470	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CLQ46_RS29515	COG1129	ABC transporter
CLQ46_RS29520	COG1172	Belongs to the binding-protein-dependent transport system permease family
CLQ46_RS29525	COG1172	Belongs to the binding-protein-dependent transport system permease family
CLQ46_RS29530	COG1454	alcohol dehydrogenase
CLQ46_RS29540	COG2211	Major facilitator Superfamily
CLQ46_RS29600	COG0205	6-phosphofructokinase activity
CLQ46_RS29620	COG3383	formate dehydrogenase (NAD+) activity
CLQ46_RS29620	COG0243	molybdopterin cofactor binding
CLQ46_RS29625	COG3383	formate dehydrogenase (NAD+) activity
CLQ46_RS29625	COG0243	molybdopterin cofactor binding
CLQ46_RS29630	COG0437	4 iron, 4 sulfur cluster binding
CLQ46_RS29635	COG2864	formate dehydrogenase
CLQ46_RS29650	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
CLQ46_RS29655	COG0657	acetylesterase activity
CLQ46_RS29660	COG0456	acetyltransferase
CLQ46_RS29675	COG1011	Hydrolase
CLQ46_RS29695	COG3852	Histidine kinase
CLQ46_RS29705	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CLQ46_RS29735	COG0204	Acyl-transferase
CLQ46_RS29745	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
CLQ46_RS29750	COG3084	Protein conserved in bacteria
CLQ46_RS29760	COG1763	Mo-molybdopterin cofactor biosynthetic process
CLQ46_RS29790	COG2186	Transcriptional regulator
CLQ46_RS29795	COG0477	Major facilitator Superfamily
CLQ46_RS29800	COG1609	Transcriptional regulator
CLQ46_RS29805	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CLQ46_RS29815	COG1172	Belongs to the binding-protein-dependent transport system permease family
CLQ46_RS29820	COG1129	ABC transporter
CLQ46_RS29850	COG1522	sequence-specific DNA binding
CLQ46_RS29855	COG0716	FMN binding
CLQ46_RS29870	COG3312	ion transport
CLQ46_RS29920	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CLQ46_RS29925	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
CLQ46_RS29930	COG0573	inorganic phosphate transmembrane transporter activity
CLQ46_RS29935	COG0581	inorganic phosphate transmembrane transporter activity
CLQ46_RS29940	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CLQ46_RS29945	COG0704	Plays a role in the regulation of phosphate uptake
CLQ46_RS29960	COG2382	esterase
CLQ46_RS29965	COG0363	glucosamine-6-phosphate deaminase activity
CLQ46_RS29970	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CLQ46_RS29980	COG2252	PERMEase
CLQ46_RS29985	COG0431	NADPH-dependent FMN reductase
CLQ46_RS30025	COG0759	Could be involved in insertion of integral membrane proteins into the membrane