locus-tag	class	description
BMD99_RS00020	COG0187	DNA topoisomerase II activity
BMD99_RS00025	COG0561	phosphatase activity
BMD99_RS00040	COG0823	Involved in the tonB-independent uptake of proteins
BMD99_RS00045	COG5645	(Lipo)protein
BMD99_RS00060	COG3645	SOS response
BMD99_RS00070	COG2188	Transcriptional regulator
BMD99_RS00085	COG2149	membrane
BMD99_RS00095	COG0641	radical SAM
BMD99_RS00105	COG2610	gluconate transmembrane transporter activity
BMD99_RS00115	COG0583	DNA-binding transcription factor activity
BMD99_RS00130	COG2814	Major facilitator Superfamily
BMD99_RS00155	COG0028	Belongs to the TPP enzyme family
BMD99_RS00160	COG0440	acetolactate synthase activity
BMD99_RS00165	COG2197	response regulator
BMD99_RS00175	COG2271	Major facilitator Superfamily
BMD99_RS00185	COG0583	DNA-binding transcription factor activity
BMD99_RS00220	COG2188	Transcriptional regulator
BMD99_RS00245	COG4580	involved in the transport of maltose and maltodextrins
BMD99_RS00250	COG1447	Phosphotransferase system cellobiose-specific component IIA
BMD99_RS00255	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BMD99_RS00255	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BMD99_RS00265	COG1609	Transcriptional regulator
BMD99_RS00275	COG3384	dioxygenase
BMD99_RS00280	COG0583	DNA-binding transcription factor activity
BMD99_RS00285	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
BMD99_RS00290	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
BMD99_RS00295	COG2828	Protein conserved in bacteria
BMD99_RS00310	COG0697	spore germination
BMD99_RS00315	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BMD99_RS00315	COG1263	PTS System
BMD99_RS00325	COG2814	Major facilitator Superfamily
BMD99_RS00335	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BMD99_RS00370	COG0583	DNA-binding transcription factor activity
BMD99_RS00395	COG1464	Belongs to the NlpA lipoprotein family
BMD99_RS00410	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
BMD99_RS00420	COG1064	alcohol dehydrogenase
BMD99_RS00455	COG2211	Major facilitator Superfamily
BMD99_RS00460	COG1501	Belongs to the glycosyl hydrolase 31 family
BMD99_RS00475	COG3547	Transposase (IS116 IS110 IS902 family)
BMD99_RS00480	COG1486	melibiose metabolic process
BMD99_RS00485	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BMD99_RS00485	COG1263	PTS System
BMD99_RS00490	COG2982	Protein involved in outer membrane biogenesis
BMD99_RS00495	COG2233	PERMEase
BMD99_RS00500	COG0786	glutamate:sodium symporter activity
BMD99_RS00520	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
BMD99_RS00545	COG3152	Membrane
BMD99_RS00555	COG1494	fructose-1,6-bisphosphatase
BMD99_RS00560	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
BMD99_RS00565	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BMD99_RS00570	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BMD99_RS00590	COG2860	membrane
BMD99_RS00600	COG2169	Transcriptional regulator
BMD99_RS00600	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BMD99_RS00610	COG1561	YicC-like family, N-terminal region
BMD99_RS00625	COG1131	(ABC) transporter
BMD99_RS00630	COG0842	Transport permease protein
BMD99_RS00660	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BMD99_RS00670	COG0227	Belongs to the bacterial ribosomal protein bL28 family
BMD99_RS00680	COG4245	von Willebrand factor, type A
BMD99_RS00715	COG1519	Transferase
BMD99_RS00720	COG1216	Glycosyl transferase, family 2
BMD99_RS00725	COG0438	transferase activity, transferring glycosyl groups
BMD99_RS00735	COG0859	PFAM glycosyl transferase family 9
BMD99_RS00760	COG0859	PFAM glycosyl transferase family 9
BMD99_RS00775	COG0156	8-amino-7-oxononanoate synthase activity
BMD99_RS00785	COG0463	Glycosyl transferase, family 2
BMD99_RS00790	COG2861	carbohydrate metabolic process
BMD99_RS00795	COG4942	peptidase
BMD99_RS00805	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BMD99_RS00810	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
BMD99_RS00830	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
BMD99_RS00840	COG2186	Transcriptional regulator
BMD99_RS00860	COG3722	fumarate hydratase activity
BMD99_RS00880	COG1566	PFAM secretion protein HlyD family protein
BMD99_RS00885	COG0625	glutathione transferase activity
BMD99_RS00895	COG3276	selenocysteine insertion sequence binding
BMD99_RS00900	COG0235	Class ii aldolase
BMD99_RS00905	COG3623	hexulose-6-phosphate isomerase
BMD99_RS00910	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
BMD99_RS00915	COG1070	Carbohydrate kinase
BMD99_RS00920	COG2271	Major facilitator Superfamily
BMD99_RS00930	COG2731	YhcH YjgK YiaL family protein
BMD99_RS00945	COG1414	Transcriptional regulator
BMD99_RS00950	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
BMD99_RS00955	COG3977	Valine--pyruvate aminotransferase
BMD99_RS00960	COG0366	Alpha amylase catalytic
BMD99_RS00965	COG2992	FlgJ-related protein
BMD99_RS00970	COG1609	Transcriptional regulator
BMD99_RS00970	COG2207	Transcriptional regulator
BMD99_RS00975	COG4214	carbohydrate transport
BMD99_RS00985	COG4213	ABC transporter substrate-binding protein
BMD99_RS01005	COG4682	membrane
BMD99_RS01010	COG3274	enterobacterial common antigen metabolic process
BMD99_RS01055	COG1278	Cold shock
BMD99_RS01060	COG2944	sequence-specific DNA binding
BMD99_RS01065	COG2814	Major facilitator Superfamily
BMD99_RS01090	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BMD99_RS01100	COG1609	Transcriptional regulator
BMD99_RS01105	COG2885	chlorophyll binding
BMD99_RS01110	COG0243	molybdopterin cofactor binding
BMD99_RS01115	COG0456	acetyltransferase
BMD99_RS01120	COG2818	Glycosylase
BMD99_RS01125	COG5571	outer membrane autotransporter
BMD99_RS01130	COG2223	nitrite transmembrane transporter activity
BMD99_RS01165	COG0747	negative chemotaxis
BMD99_RS01170	COG0601	transmembrane transport
BMD99_RS01175	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BMD99_RS01180	COG0444	Belongs to the ABC transporter superfamily
BMD99_RS01185	COG4608	Belongs to the ABC transporter superfamily
BMD99_RS01205	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
BMD99_RS01210	COG0457	Tetratricopeptide repeat
BMD99_RS01210	COG3118	belongs to the thioredoxin family
BMD99_RS01215	COG2199	diguanylate cyclase activity
BMD99_RS01215	COG2200	EAL domain
BMD99_RS01225	COG0612	Peptidase, M16
BMD99_RS01240	COG2982	Protein involved in outer membrane biogenesis
BMD99_RS01245	COG0477	Major facilitator Superfamily
BMD99_RS01250	COG1295	ribonuclease BN
BMD99_RS01255	COG0583	DNA-binding transcription factor activity
BMD99_RS01260	COG1028	Short-chain dehydrogenase reductase Sdr
BMD99_RS01275	COG1454	alcohol dehydrogenase
BMD99_RS01285	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BMD99_RS01290	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
BMD99_RS01295	COG0671	phosphoesterase, PA-phosphatase related
BMD99_RS01315	COG0589	response to stress
BMD99_RS01325	COG0306	phosphate transporter
BMD99_RS01330	COG2081	HI0933 family
BMD99_RS01335	COG2239	Acts as a magnesium transporter
BMD99_RS01355	COG1124	(ABC) transporter
BMD99_RS01365	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BMD99_RS01370	COG0601	transmembrane transport
BMD99_RS01375	COG0747	negative chemotaxis
BMD99_RS01390	COG3479	Phenolic acid decarboxylase
BMD99_RS01430	COG0628	permease
BMD99_RS01435	COG0477	Major facilitator Superfamily
BMD99_RS01445	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
BMD99_RS01455	COG2217	Heavy metal translocating P-type atpase
BMD99_RS01460	COG3714	YhhN family
BMD99_RS01470	COG3776	membrane
BMD99_RS01475	COG0742	ribosomal rna small subunit methyltransferase
BMD99_RS01480	COG0552	protein localization to endoplasmic reticulum
BMD99_RS01485	COG2884	Cell division ATP-binding protein ftsE
BMD99_RS01490	COG2177	Part of the ABC transporter FtsEX involved in
BMD99_RS01505	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
BMD99_RS01515	COG0683	leucine binding
BMD99_RS01520	COG4907	membrane protein (DUF2207)
BMD99_RS01525	COG1704	LemA family
BMD99_RS01540	COG0683	leucine binding
BMD99_RS01545	COG0559	Belongs to the binding-protein-dependent transport system permease family
BMD99_RS01595	COG0584	glycerophosphoryl diester phosphodiesterase
BMD99_RS01605	COG0405	Gamma-glutamyltransferase
BMD99_RS01610	COG1247	-acetyltransferase
BMD99_RS01615	COG0673	inositol 2-dehydrogenase activity
BMD99_RS01620	COG1741	Belongs to the pirin family
BMD99_RS01625	COG1609	Transcriptional regulator
BMD99_RS01630	COG3265	gluconokinase activity
BMD99_RS01635	COG2610	gluconate transmembrane transporter activity
BMD99_RS01645	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
BMD99_RS01670	COG0058	SHG alpha-glucan phosphorylase activity
BMD99_RS01685	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
BMD99_RS01700	COG1349	DNA-binding transcription factor activity
BMD99_RS01715	COG0058	SHG alpha-glucan phosphorylase activity
BMD99_RS01720	COG1640	4-alpha-glucanotransferase
BMD99_RS01725	COG2610	gluconate transmembrane transporter activity
BMD99_RS01735	COG1040	competence protein
BMD99_RS01760	COG1918	ferrous iron import across plasma membrane
BMD99_RS01765	COG2183	response to ionizing radiation
BMD99_RS01770	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BMD99_RS01795	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
BMD99_RS01800	COG1011	Hydrolase
BMD99_RS01810	COG0494	nUDIX hydrolase
BMD99_RS01815	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
BMD99_RS01840	COG4796	Type ii and iii secretion system protein
BMD99_RS01860	COG3266	domain, Protein
BMD99_RS01865	COG0338	D12 class N6 adenine-specific DNA methyltransferase
BMD99_RS01870	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
BMD99_RS01885	COG3385	transposase activity
BMD99_RS01900	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BMD99_RS01905	COG0402	S-adenosylhomocysteine deaminase activity
BMD99_RS01910	COG0738	Major facilitator superfamily
BMD99_RS01935	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BMD99_RS01940	COG1289	transmembrane transporter activity
BMD99_RS01950	COG1765	OsmC-like protein
BMD99_RS01955	COG3954	Phosphoribulokinase
BMD99_RS01965	COG0429	hydrolase of the alpha beta-hydrolase fold
BMD99_RS01975	COG0488	(ABC) transporter
BMD99_RS01990	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
BMD99_RS01995	COG1047	Peptidyl-prolyl cis-trans
BMD99_RS02005	COG0545	Peptidyl-prolyl cis-trans isomerase
BMD99_RS02010	COG2964	Protein conserved in bacteria
BMD99_RS02065	COG0051	transcription antitermination factor activity, RNA binding
BMD99_RS02090	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
BMD99_RS02105	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
BMD99_RS02170	COG0201	protein transport
BMD99_RS02185	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
BMD99_RS02195	COG0202	RNA polymerase activity
BMD99_RS02210	COG0789	Transcriptional regulator
BMD99_RS02215	COG3036	rescue of stalled ribosome
BMD99_RS02245	COG0758	DNA mediated transformation
BMD99_RS02255	COG0551	DNA topoisomerase type I activity
BMD99_RS02275	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
BMD99_RS02310	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BMD99_RS02315	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BMD99_RS02320	COG1309	transcriptional regulator
BMD99_RS02340	COG4145	pantothenate transmembrane transporter activity
BMD99_RS02345	COG3924	membrane
BMD99_RS02350	COG0439	Biotin carboxylase
BMD99_RS02355	COG0511	ligase activity, forming carbon-carbon bonds
BMD99_RS02380	COG2200	EAL domain
BMD99_RS02380	COG2199	diguanylate cyclase activity
BMD99_RS02385	COG1077	Cell shape determining protein MreB Mrl
BMD99_RS02390	COG1792	Involved in formation and maintenance of cell shape
BMD99_RS02395	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
BMD99_RS02405	COG1530	ribonuclease E activity
BMD99_RS02410	COG3164	Protein of unknown function
BMD99_RS02415	COG0312	modulator of DNA gyrase
BMD99_RS02420	COG0583	DNA-binding transcription factor activity
BMD99_RS02435	COG1289	transmembrane transporter activity
BMD99_RS02440	COG2732	(Barnase) inhibitor
BMD99_RS02480	COG0471	metal ion transport
BMD99_RS02485	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
BMD99_RS02490	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
BMD99_RS02515	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BMD99_RS02520	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BMD99_RS02525	COG3105	Protein conserved in bacteria
BMD99_RS02530	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
BMD99_RS02550	COG0625	glutathione transferase activity
BMD99_RS02555	COG2969	positive regulation of protein catabolic process
BMD99_RS02565	COG0493	'glutamate synthase
BMD99_RS02570	COG0067	glutamate synthase
BMD99_RS02570	COG0070	glutamate synthase
BMD99_RS02570	COG0069	glutamate synthase activity
BMD99_RS02575	COG1242	4 iron, 4 sulfur cluster binding
BMD99_RS02580	COG2271	Major facilitator Superfamily
BMD99_RS02585	COG1063	alcohol dehydrogenase
BMD99_RS02590	COG1312	Catalyzes the dehydration of D-mannonate
BMD99_RS02595	COG2198	Histidine kinase
BMD99_RS02595	COG0784	Response regulator, receiver
BMD99_RS02595	COG5002	protein histidine kinase activity
BMD99_RS02600	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
BMD99_RS02605	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BMD99_RS02610	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
BMD99_RS02615	COG0583	DNA-binding transcription factor activity
BMD99_RS02675	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BMD99_RS02685	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BMD99_RS02690	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
BMD99_RS02695	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
BMD99_RS02700	COG1137	ATPase activity
BMD99_RS02705	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
BMD99_RS02710	COG3117	lipopolysaccharide transmembrane transporter activity
BMD99_RS02715	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
BMD99_RS02725	COG0530	calcium, potassium:sodium antiporter activity
BMD99_RS02735	COG1127	ABC transporter
BMD99_RS02740	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
BMD99_RS02745	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
BMD99_RS02750	COG2854	intermembrane phospholipid transfer
BMD99_RS02755	COG3113	response to antibiotic
BMD99_RS02760	COG5007	Belongs to the BolA IbaG family
BMD99_RS02770	COG3423	Transcriptional regulator
BMD99_RS02775	COG0142	geranyltranstransferase activity
BMD99_RS02790	COG0697	spore germination
BMD99_RS02800	COG2027	D-alanyl-D-alanine carboxypeptidase
BMD99_RS02810	COG1534	Rna-binding protein
BMD99_RS02820	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BMD99_RS02825	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
BMD99_RS02835	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BMD99_RS02875	COG0195	Participates in both transcription termination and antitermination
BMD99_RS02925	COG0814	amino acid
BMD99_RS02950	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
BMD99_RS02995	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BMD99_RS03000	COG0826	peptidase U32
BMD99_RS03005	COG0826	peptidase U32
BMD99_RS03010	COG3154	lipid carrier protein
BMD99_RS03015	COG3153	acetyltransferase
BMD99_RS03030	COG0693	protein deglycase activity
BMD99_RS03035	COG0702	epimerase
BMD99_RS03040	COG0701	Predicted permease
BMD99_RS03045	COG2823	Periplasmic or secreted lipoprotein
BMD99_RS03065	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
BMD99_RS03080	COG1063	alcohol dehydrogenase
BMD99_RS03085	COG3775	system Galactitol-specific IIC component
BMD99_RS03090	COG3414	Phosphotransferase system galactitol-specific IIB component
BMD99_RS03095	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BMD99_RS03105	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BMD99_RS03105	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
BMD99_RS03110	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BMD99_RS03110	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BMD99_RS03110	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BMD99_RS03115	COG1105	Belongs to the carbohydrate kinase PfkB family
BMD99_RS03130	COG1349	DNA-binding transcription factor activity
BMD99_RS03135	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BMD99_RS03140	COG2721	sulfolactate sulfo-lyase activity
BMD99_RS03145	COG2271	Major facilitator Superfamily
BMD99_RS03155	COG2084	Dehydrogenase
BMD99_RS03160	COG1929	Belongs to the glycerate kinase type-1 family
BMD99_RS03180	COG1741	Belongs to the pirin family
BMD99_RS03185	COG0583	DNA-binding transcription factor activity
BMD99_RS03190	COG3152	Membrane
BMD99_RS03195	COG0435	Glutathione S-transferase
BMD99_RS03200	COG2259	Doxx family
BMD99_RS03210	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
BMD99_RS03215	COG4575	ribosome binding
BMD99_RS03220	COG1422	Protein of unknown function (DUF1090)
BMD99_RS03230	COG0586	Pfam SNARE associated Golgi protein
BMD99_RS03235	COG2186	Transcriptional regulator
BMD99_RS03240	COG2271	Major facilitator Superfamily
BMD99_RS03250	COG2721	sulfolactate sulfo-lyase activity
BMD99_RS03265	COG0861	Integral membrane protein TerC family
BMD99_RS03270	COG0673	inositol 2-dehydrogenase activity
BMD99_RS03275	COG1451	nucleotide metabolic process
BMD99_RS03285	COG0446	pyridine nucleotide-disulphide oxidoreductase
BMD99_RS03285	COG1902	pentaerythritol trinitrate reductase activity
BMD99_RS03340	COG1695	Transcriptional regulator
BMD99_RS03345	COG2375	cellular response to nickel ion
BMD99_RS03360	COG1461	Dihydroxyacetone kinase
BMD99_RS03365	COG2376	Dihydroxyacetone kinase
BMD99_RS03445	COG3247	response to pH
BMD99_RS03455	COG0784	Response regulator, receiver
BMD99_RS03455	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BMD99_RS03455	COG2198	Histidine kinase
BMD99_RS03455	COG2205	protein histidine kinase activity
BMD99_RS03460	COG2197	response regulator
BMD99_RS03485	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BMD99_RS03490	COG0358	DNA primase activity
BMD99_RS03495	COG0828	Belongs to the bacterial ribosomal protein bS21 family
BMD99_RS03550	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
BMD99_RS03565	COG4991	sh3 domain protein
BMD99_RS03570	COG3025	triphosphatase activity
BMD99_RS03595	COG2960	long-chain fatty acid transporting porin activity
BMD99_RS03610	COG3384	dioxygenase
BMD99_RS03615	COG0754	glutathionylspermidine amidase activity
BMD99_RS03630	COG0494	nUDIX hydrolase
BMD99_RS03635	COG3151	Protein conserved in bacteria
BMD99_RS03640	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
BMD99_RS03645	COG3150	esterase
BMD99_RS03655	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
BMD99_RS03660	COG2249	NAD(P)H dehydrogenase (quinone) activity
BMD99_RS03665	COG0642	Histidine kinase
BMD99_RS03675	COG3111	PFAM Bacterial OB fold (BOF) protein
BMD99_RS03680	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
BMD99_RS03685	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BMD99_RS03690	COG0204	Acyl-transferase
BMD99_RS03695	COG2132	Multicopper oxidase
BMD99_RS03700	COG1032	radical SAM domain protein
BMD99_RS03705	COG0656	L-ascorbic acid biosynthetic process
BMD99_RS03710	COG1979	alcohol dehydrogenase
BMD99_RS03715	COG2207	Transcriptional regulator
BMD99_RS03720	COG0586	Pfam SNARE associated Golgi protein
BMD99_RS03725	COG0626	cystathionine gamma-synthase activity
BMD99_RS03735	COG0848	biopolymer transport protein
BMD99_RS03755	COG0625	glutathione transferase activity
BMD99_RS03765	COG0754	glutathionylspermidine amidase activity
BMD99_RS03770	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BMD99_RS03790	COG0583	DNA-binding transcription factor activity
BMD99_RS03795	COG0626	cystathionine gamma-synthase activity
BMD99_RS03860	COG0582	viral genome integration into host DNA
BMD99_RS03870	COG1811	Na channel or pump
BMD99_RS03880	COG1982	Orn Lys Arg decarboxylase major
BMD99_RS03885	COG2211	Major facilitator Superfamily
BMD99_RS03900	COG1194	a g-specific adenine glycosylase
BMD99_RS03910	COG3171	Protein conserved in bacteria
BMD99_RS03920	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BMD99_RS03935	COG0762	integral membrane protein
BMD99_RS03940	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
BMD99_RS03945	COG2805	Type II/IV secretion system protein
BMD99_RS03970	COG1385	rRNA (uridine-N3-)-methyltransferase activity
BMD99_RS03975	COG2356	endonuclease I
BMD99_RS03985	COG2814	Major facilitator Superfamily
BMD99_RS04020	COG0501	Belongs to the peptidase M48B family
BMD99_RS04025	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
BMD99_RS04040	COG0191	fructose-bisphosphate aldolase activity
BMD99_RS04045	COG0668	transmembrane transport
BMD99_RS04055	COG2968	Membrane
BMD99_RS04065	COG3385	transposase activity
BMD99_RS04080	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BMD99_RS04085	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
BMD99_RS04105	COG0006	proline dipeptidase activity
BMD99_RS04110	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BMD99_RS04115	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BMD99_RS04135	COG1028	Short-chain dehydrogenase reductase Sdr
BMD99_RS04140	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BMD99_RS04160	COG2723	6-phospho-beta-galactosidase activity
BMD99_RS04165	COG1737	Transcriptional regulator
BMD99_RS04175	COG1272	protein, Hemolysin III
BMD99_RS04190	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
BMD99_RS04200	COG0716	FMN binding
BMD99_RS04205	COG4974	Belongs to the 'phage' integrase family
BMD99_RS04215	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
BMD99_RS04235	COG1811	Na channel or pump
BMD99_RS04245	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
BMD99_RS04250	COG0583	DNA-binding transcription factor activity
BMD99_RS04255	COG4942	peptidase
BMD99_RS04295	COG0582	viral genome integration into host DNA
BMD99_RS04305	COG3335	DDE superfamily endonuclease
BMD99_RS04355	COG3344	reverse transcriptase
BMD99_RS04380	COG2814	Major facilitator Superfamily
BMD99_RS04385	COG0583	DNA-binding transcription factor activity
BMD99_RS04395	COG0667	Aldo Keto reductase
BMD99_RS04400	COG2249	NAD(P)H dehydrogenase (quinone) activity
BMD99_RS04435	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
BMD99_RS04440	COG1393	Belongs to the ArsC family
BMD99_RS04460	COG1538	Outer membrane efflux protein
BMD99_RS04465	COG1289	transmembrane transporter activity
BMD99_RS04480	COG3592	Divergent 4Fe-4S mono-cluster
BMD99_RS04485	COG2388	GCN5-related N-acetyl-transferase
BMD99_RS04495	COG3539	Fimbrial protein
BMD99_RS04500	COG3539	Fimbrial protein
BMD99_RS04505	COG3539	Fimbrial protein
BMD99_RS04510	COG3188	usher protein
BMD99_RS04515	COG3121	Chaperone
BMD99_RS04520	COG3539	Fimbrial protein
BMD99_RS04530	COG4974	Belongs to the 'phage' integrase family
BMD99_RS04535	COG0582	viral genome integration into host DNA
BMD99_RS04550	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
BMD99_RS04555	COG1846	Transcriptional regulator
BMD99_RS04560	COG0697	spore germination
BMD99_RS04610	COG0667	Aldo Keto reductase
BMD99_RS04615	COG0814	amino acid
BMD99_RS04630	COG0183	Belongs to the thiolase family
BMD99_RS04640	COG0823	Involved in the tonB-independent uptake of proteins
BMD99_RS04645	COG1028	Short-chain dehydrogenase reductase Sdr
BMD99_RS04650	COG2814	Major facilitator Superfamily
BMD99_RS04680	COG3842	ATPase activity
BMD99_RS04685	COG0395	ABC-type sugar transport system, permease component
BMD99_RS04690	COG1175	transmembrane transport
BMD99_RS04695	COG1917	Cupin 2, conserved barrel domain protein
BMD99_RS04700	COG1794	racemase activity, acting on amino acids and derivatives
BMD99_RS04705	COG0583	DNA-binding transcription factor activity
BMD99_RS04715	COG1609	Transcriptional regulator
BMD99_RS04720	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BMD99_RS04725	COG2723	6-phospho-beta-galactosidase activity
BMD99_RS04730	COG2186	Transcriptional regulator
BMD99_RS04740	COG1609	Transcriptional regulator
BMD99_RS04765	COG0667	Aldo Keto reductase
BMD99_RS04775	COG0861	Integral membrane protein TerC family
BMD99_RS04815	COG2165	general secretion pathway protein
BMD99_RS04820	COG4795	General secretion pathway protein
BMD99_RS04830	COG4967	type IV pilus modification protein PilV
BMD99_RS04835	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
BMD99_RS04840	COG1025	Belongs to the peptidase M16 family
BMD99_RS04845	COG1074	ATP-dependent DNA helicase activity
BMD99_RS04850	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
BMD99_RS04865	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
BMD99_RS04865	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
BMD99_RS04870	COG0860	N-Acetylmuramoyl-L-alanine amidase
BMD99_RS04875	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BMD99_RS04905	COG4656	Part of a membrane complex involved in electron transport
BMD99_RS04910	COG1454	alcohol dehydrogenase
BMD99_RS04910	COG1012	belongs to the aldehyde dehydrogenase family
BMD99_RS05155	COG2885	chlorophyll binding
BMD99_RS05180	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
BMD99_RS05185	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
BMD99_RS05190	COG2166	iron-sulfur cluster assembly
BMD99_RS05195	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BMD99_RS05205	COG0583	DNA-binding transcription factor activity
BMD99_RS05210	COG2363	Small membrane protein
BMD99_RS05220	COG1349	DNA-binding transcription factor activity
BMD99_RS05240	COG0738	Major facilitator superfamily
BMD99_RS05245	COG0235	Class ii aldolase
BMD99_RS05250	COG1454	alcohol dehydrogenase
BMD99_RS05265	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BMD99_RS05280	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
BMD99_RS05285	COG2011	ABC-type metal ion transport system permease component
BMD99_RS05300	COG0477	Major facilitator Superfamily
BMD99_RS05310	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BMD99_RS05315	COG1760	l-serine dehydratase
BMD99_RS05320	COG0814	amino acid
BMD99_RS05325	COG1611	Belongs to the LOG family
BMD99_RS05340	COG3098	single-species biofilm formation
BMD99_RS05345	COG0564	pseudouridine synthase activity
BMD99_RS05350	COG0716	FMN binding
BMD99_RS05355	COG2271	Major facilitator Superfamily
BMD99_RS05360	COG4948	Mandelate Racemase Muconate Lactonizing
BMD99_RS05365	COG4948	Mandelate Racemase Muconate Lactonizing
BMD99_RS05370	COG1929	Belongs to the glycerate kinase type-1 family
BMD99_RS05375	COG2205	protein histidine kinase activity
BMD99_RS05375	COG3437	response regulator, receiver
BMD99_RS05375	COG4999	Histidine kinase
BMD99_RS05375	COG3850	Histidine kinase
BMD99_RS05385	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BMD99_RS05390	COG3956	TIGRFAM MazG family protein
BMD99_RS05410	COG0602	queuosine metabolic process
BMD99_RS05415	COG1070	Carbohydrate kinase
BMD99_RS05420	COG2223	nitrite transmembrane transporter activity
BMD99_RS05425	COG1028	Short-chain dehydrogenase reductase Sdr
BMD99_RS05430	COG0277	FAD linked oxidase domain protein
BMD99_RS05435	COG0477	Major facilitator Superfamily
BMD99_RS05440	COG2086	electron transfer activity
BMD99_RS05445	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
BMD99_RS05450	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
BMD99_RS05455	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
BMD99_RS05460	COG0644	oxidoreductase
BMD99_RS05465	COG0720	synthase
BMD99_RS05485	COG1203	CRISPR-associated helicase, Cas3
BMD99_RS05500	COG1857	crispr-associated protein
BMD99_RS05515	COG1518	maintenance of DNA repeat elements
BMD99_RS05520	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
BMD99_RS05535	COG2234	aminopeptidase activity
BMD99_RS05595	COG4942	peptidase
BMD99_RS05595	COG1388	LysM domain
BMD99_RS05600	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BMD99_RS05625	COG0163	prenyltransferase activity
BMD99_RS05630	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
BMD99_RS05670	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BMD99_RS05675	COG4558	Periplasmic binding protein
BMD99_RS05680	COG3720	iron ion transport
BMD99_RS05700	COG0679	Auxin Efflux Carrier
BMD99_RS05715	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BMD99_RS05720	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BMD99_RS05725	COG1121	(ABC) transporter
BMD99_RS05735	COG1609	Transcriptional regulator
BMD99_RS05740	COG1940	carbohydrate kinase activity
BMD99_RS05745	COG1447	Phosphotransferase system cellobiose-specific component IIA
BMD99_RS05750	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BMD99_RS05755	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BMD99_RS05760	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BMD99_RS05770	COG4580	involved in the transport of maltose and maltodextrins
BMD99_RS05780	COG2723	6-phospho-beta-galactosidase activity
BMD99_RS05790	COG0309	Hydrogenase expression formation protein (HypE)
BMD99_RS05795	COG0409	Hydrogenase expression formation protein
BMD99_RS05800	COG0298	carbon dioxide binding
BMD99_RS05805	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
BMD99_RS05825	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
BMD99_RS05830	COG0651	ATP synthesis coupled electron transport
BMD99_RS05835	COG0650	Formate hydrogenlyase subunit 4
BMD99_RS05840	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
BMD99_RS05840	COG3261	NADH dehydrogenase
BMD99_RS05845	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BMD99_RS05850	COG3260	NADH ubiquinone oxidoreductase 20
BMD99_RS05860	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
BMD99_RS05870	COG2723	6-phospho-beta-galactosidase activity
BMD99_RS05875	COG1263	PTS System
BMD99_RS05875	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BMD99_RS05885	COG1609	Transcriptional regulator
BMD99_RS05890	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
BMD99_RS05895	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
BMD99_RS05900	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
BMD99_RS05930	COG1349	DNA-binding transcription factor activity
BMD99_RS05935	COG4578	phosphoenolpyruvate-dependent sugar phosphotransferase system
BMD99_RS05940	COG1028	Short-chain dehydrogenase reductase Sdr
BMD99_RS05950	COG3732	PTS system glucitol sorbitol-specific
BMD99_RS05955	COG3730	PTS system glucitol sorbitol-specific
BMD99_RS05960	COG2951	lytic endotransglycosylase activity
BMD99_RS05970	COG3547	Transposase (IS116 IS110 IS902 family)
BMD99_RS05980	COG1121	(ABC) transporter
BMD99_RS05985	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BMD99_RS05990	COG0803	Belongs to the bacterial solute-binding protein 9 family
BMD99_RS05995	COG1546	Belongs to the CinA family
BMD99_RS06020	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
BMD99_RS06045	COG2823	Periplasmic or secreted lipoprotein
BMD99_RS06050	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BMD99_RS06055	COG1238	metal cluster binding
BMD99_RS06075	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BMD99_RS06080	COG2814	Major facilitator Superfamily
BMD99_RS06085	COG1566	PFAM secretion protein HlyD family protein
BMD99_RS06090	COG1846	Transcriptional regulator
BMD99_RS06100	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
BMD99_RS06110	COG4176	ABC-type proline glycine betaine transport system permease component
BMD99_RS06125	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BMD99_RS06135	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
BMD99_RS06140	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BMD99_RS06145	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BMD99_RS06150	COG4575	ribosome binding
BMD99_RS06190	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BMD99_RS06195	COG0640	Transcriptional regulator
BMD99_RS06205	COG0583	DNA-binding transcription factor activity
BMD99_RS06210	COG0671	phosphoesterase, PA-phosphatase related
BMD99_RS06215	COG3284	Transcriptional regulator
BMD99_RS06230	COG3121	Chaperone
BMD99_RS06250	COG3188	usher protein
BMD99_RS06265	COG2197	response regulator
BMD99_RS06290	COG0235	Class ii aldolase
BMD99_RS06295	COG1126	abc transporter atp-binding protein
BMD99_RS06300	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BMD99_RS06350	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BMD99_RS06355	COG2207	Transcriptional regulator
BMD99_RS06355	COG3708	Transcriptional regulator
BMD99_RS06365	COG0583	DNA-binding transcription factor activity
BMD99_RS06385	COG2867	negative regulation of translational initiation
BMD99_RS06400	COG0497	DNA recombination
BMD99_RS06415	COG4536	flavin adenine dinucleotide binding
BMD99_RS06420	COG4137	Cytochrome C assembly protein
BMD99_RS06425	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
BMD99_RS06465	COG2885	chlorophyll binding
BMD99_RS06470	COG2199	diguanylate cyclase activity
BMD99_RS06480	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
BMD99_RS06485	COG0287	Prephenate dehydrogenase
BMD99_RS06485	COG1605	Chorismate mutase
BMD99_RS06495	COG1605	Chorismate mutase
BMD99_RS06495	COG0077	Prephenate dehydratase
BMD99_RS06505	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
BMD99_RS06510	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BMD99_RS06525	COG0542	response to heat
BMD99_RS06555	COG0477	Major facilitator Superfamily
BMD99_RS06560	COG5544	Lipoprotein
BMD99_RS06565	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BMD99_RS06575	COG3148	PFAM DTW domain containing protein
BMD99_RS06580	COG3118	belongs to the thioredoxin family
BMD99_RS06585	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BMD99_RS06600	COG0513	Belongs to the DEAD box helicase family
BMD99_RS06610	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
BMD99_RS06630	COG3026	antisigma factor binding
BMD99_RS06635	COG3086	response to oxidative stress
BMD99_RS06645	COG0681	Belongs to the peptidase S26 family
BMD99_RS06665	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
BMD99_RS06675	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
BMD99_RS06690	COG1737	Transcriptional regulator
BMD99_RS06695	COG0560	Phosphoserine phosphatase
BMD99_RS06715	COG0047	phosphoribosylformylglycinamidine synthase activity
BMD99_RS06715	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BMD99_RS06720	COG2205	protein histidine kinase activity
BMD99_RS06725	COG3170	Tfp pilus assembly protein FimV
BMD99_RS06730	COG2204	response regulator
BMD99_RS06735	COG0347	Belongs to the P(II) protein family
BMD99_RS06740	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BMD99_RS06740	COG1017	nitric oxide dioxygenase activity
BMD99_RS06755	COG2259	Doxx family
BMD99_RS06760	COG1940	carbohydrate kinase activity
BMD99_RS06765	COG0457	Tetratricopeptide repeat
BMD99_RS06770	COG0477	Major facilitator Superfamily
BMD99_RS06770	COG2814	Major facilitator Superfamily
BMD99_RS06775	COG2017	converts alpha-aldose to the beta-anomer
BMD99_RS06780	COG2814	Major facilitator Superfamily
BMD99_RS06785	COG3711	transcriptional antiterminator
BMD99_RS06790	COG3683	transport system, periplasmic component
BMD99_RS06795	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
BMD99_RS06825	COG0822	iron-sulfur transferase activity
BMD99_RS06845	COG0633	Ferredoxin
BMD99_RS06850	COG2975	iron-sulfur cluster assembly
BMD99_RS06875	COG2897	thiosulfate sulfurtransferase activity
BMD99_RS06880	COG2373	Large extracellular alpha-helical protein
BMD99_RS06885	COG4953	penicillin-binding protein 1C
BMD99_RS06915	COG2976	Protein conserved in bacteria
BMD99_RS06980	COG3039	Transposase
BMD99_RS07095	COG1645	bacterial-type flagellum-dependent swarming motility
BMD99_RS07105	COG0516	GMP reductase activity
BMD99_RS07105	COG0517	IMP dehydrogenase activity
BMD99_RS07115	COG0582	viral genome integration into host DNA
BMD99_RS07130	COG3119	arylsulfatase activity
BMD99_RS07135	COG0641	radical SAM
BMD99_RS07155	COG2200	EAL domain
BMD99_RS07170	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
BMD99_RS07185	COG2723	6-phospho-beta-galactosidase activity
BMD99_RS07195	COG2233	PERMEase
BMD99_RS07210	COG1393	Belongs to the ArsC family
BMD99_RS07215	COG4783	chaperone-mediated protein folding
BMD99_RS07220	COG0628	permease
BMD99_RS07225	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
BMD99_RS07230	COG2716	regulation of RNA biosynthetic process
BMD99_RS07240	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
BMD99_RS07250	COG2321	neutral zinc metallopeptidase
BMD99_RS07255	COG1444	tRNA N-acetyltransferase activity
BMD99_RS07260	COG0400	carboxylic ester hydrolase activity
BMD99_RS07275	COG1393	Belongs to the ArsC family
BMD99_RS07285	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BMD99_RS07295	COG0493	'glutamate synthase
BMD99_RS07295	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
BMD99_RS07305	COG5342	invasion associated locus B
BMD99_RS07310	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
BMD99_RS07325	COG4810	utilization protein
BMD99_RS07355	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
BMD99_RS07415	COG0860	N-Acetylmuramoyl-L-alanine amidase
BMD99_RS07435	COG2837	iron assimilation
BMD99_RS07445	COG4150	thiosulfate binding
BMD99_RS07450	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
BMD99_RS07455	COG4208	sulfate ABC transporter
BMD99_RS07460	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
BMD99_RS07470	COG4319	ketosteroid isomerase
BMD99_RS07515	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BMD99_RS07535	COG3530	Putative quorum-sensing-regulated virulence factor
BMD99_RS07540	COG0385	Bile acid
BMD99_RS07545	COG0583	DNA-binding transcription factor activity
BMD99_RS07580	COG3415	Transposase
BMD99_RS07585	COG3415	Transposase
BMD99_RS07600	COG2199	diguanylate cyclase activity
BMD99_RS07600	COG2200	EAL domain
BMD99_RS07605	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BMD99_RS07620	COG0667	Aldo Keto reductase
BMD99_RS07625	COG3961	Belongs to the TPP enzyme family
BMD99_RS07640	COG3279	Response regulator of the LytR AlgR family
BMD99_RS07645	COG3275	phosphorelay sensor kinase activity
BMD99_RS07650	COG0436	Aminotransferase
BMD99_RS07660	COG2807	transmembrane transport
BMD99_RS07665	COG0590	tRNA wobble adenosine to inosine editing
BMD99_RS07670	COG0583	DNA-binding transcription factor activity
BMD99_RS07720	COG2116	formate transmembrane transporter activity
BMD99_RS07725	COG2853	Lipoprotein
BMD99_RS07735	COG3691	Protein conserved in bacteria
BMD99_RS07750	COG2062	phosphohistidine phosphatase, SixA
BMD99_RS07775	COG0730	response to heat
BMD99_RS07780	COG3101	peptidyl-lysine hydroxylation
BMD99_RS07795	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BMD99_RS07805	COG2188	Transcriptional regulator
BMD99_RS07815	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BMD99_RS07820	COG1447	Phosphotransferase system cellobiose-specific component IIA
BMD99_RS07840	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
BMD99_RS07850	COG0586	Pfam SNARE associated Golgi protein
BMD99_RS07860	COG0285	dihydrofolate synthase activity
BMD99_RS07865	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
BMD99_RS07870	COG1286	toxin biosynthetic process
BMD99_RS07875	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
BMD99_RS07880	COG0163	prenyltransferase activity
BMD99_RS07900	COG4160	amino acid transport
BMD99_RS07905	COG4598	ABC transporter
BMD99_RS07915	COG1090	epimerase
BMD99_RS07920	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
BMD99_RS07925	COG0625	glutathione transferase activity
BMD99_RS07930	COG0625	glutathione transferase activity
BMD99_RS07935	COG0622	Phosphoesterase
BMD99_RS07940	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
BMD99_RS07945	COG0280	phosphate acetyltransferase
BMD99_RS07945	COG0857	belongs to the CobB CobQ family
BMD99_RS07965	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BMD99_RS07970	COG0471	metal ion transport
BMD99_RS07970	COG0490	domain, Protein
BMD99_RS07980	COG0436	Aminotransferase
BMD99_RS07985	COG0583	DNA-binding transcription factor activity
BMD99_RS08035	COG0839	Belongs to the complex I subunit 6 family
BMD99_RS08045	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
BMD99_RS08050	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BMD99_RS08065	COG2153	protein acetylation
BMD99_RS08070	COG1169	isochorismate synthase
BMD99_RS08095	COG0318	PFAM AMP-dependent synthetase and ligase
BMD99_RS08105	COG5464	transposase or invertase
BMD99_RS08120	COG1414	Transcriptional regulator
BMD99_RS08130	COG2271	Major facilitator Superfamily
BMD99_RS08140	COG0247	lactate metabolic process
BMD99_RS08150	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
BMD99_RS08155	COG0583	DNA-binding transcription factor activity
BMD99_RS08160	COG2814	Major facilitator Superfamily
BMD99_RS08165	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BMD99_RS08205	COG0642	Histidine kinase
BMD99_RS08205	COG2198	Histidine kinase
BMD99_RS08220	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BMD99_RS08220	COG2169	Transcriptional regulator
BMD99_RS08225	COG3145	DNA-N1-methyladenine dioxygenase activity
BMD99_RS08230	COG4615	Cyclic peptide transporter
BMD99_RS08235	COG2239	Acts as a magnesium transporter
BMD99_RS08240	COG0659	secondary active sulfate transmembrane transporter activity
BMD99_RS08255	COG0628	permease
BMD99_RS08280	COG1349	DNA-binding transcription factor activity
BMD99_RS08285	COG0494	nUDIX hydrolase
BMD99_RS08295	COG1061	Type III restriction enzyme res subunit
BMD99_RS08305	COG2814	Major facilitator Superfamily
BMD99_RS08320	COG4172	Belongs to the ABC transporter superfamily
BMD99_RS08325	COG4239	(ABC) transporter, permease
BMD99_RS08330	COG4174	ABC transporter (Permease)
BMD99_RS08335	COG4166	transmembrane transport
BMD99_RS08340	COG2200	EAL domain
BMD99_RS08345	COG0791	NLP P60 protein
BMD99_RS08350	COG0671	phosphoesterase, PA-phosphatase related
BMD99_RS08355	COG0523	cobalamin synthesis protein
BMD99_RS08360	COG0246	Mannitol dehydrogenase
BMD99_RS08365	COG1312	Catalyzes the dehydration of D-mannonate
BMD99_RS08370	COG3385	transposase activity
BMD99_RS08395	COG1566	PFAM secretion protein HlyD family protein
BMD99_RS08415	COG1105	Belongs to the carbohydrate kinase PfkB family
BMD99_RS08420	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BMD99_RS08420	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
BMD99_RS08420	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BMD99_RS08430	COG2855	membrane
BMD99_RS08440	COG0583	DNA-binding transcription factor activity
BMD99_RS08445	COG0833	amino acid
BMD99_RS08450	COG4771	TonB-dependent receptor
BMD99_RS08465	COG2311	Membrane
BMD99_RS08480	COG1129	ABC transporter
BMD99_RS08500	COG2949	membrane
BMD99_RS08505	COG3547	Transposase (IS116 IS110 IS902 family)
BMD99_RS08520	COG1346	cytolysis
BMD99_RS08530	COG0583	DNA-binding transcription factor activity
BMD99_RS08535	COG2271	Major facilitator Superfamily
BMD99_RS08555	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BMD99_RS08560	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BMD99_RS08565	COG3659	wide pore channel activity
BMD99_RS08580	COG2723	6-phospho-beta-galactosidase activity
BMD99_RS08585	COG2226	methyltransferase
BMD99_RS08590	COG1538	Outer membrane efflux protein
BMD99_RS08595	COG0586	Pfam SNARE associated Golgi protein
BMD99_RS08605	COG1686	Belongs to the peptidase S11 family
BMD99_RS08625	COG0277	FAD linked oxidase domain protein
BMD99_RS08630	COG1472	Belongs to the glycosyl hydrolase 3 family
BMD99_RS08635	COG1732	Glycine betaine
BMD99_RS08640	COG1174	glycine betaine transport
BMD99_RS08645	COG1125	glycine betaine transport
BMD99_RS08650	COG1174	glycine betaine transport
BMD99_RS08660	COG3275	phosphorelay sensor kinase activity
BMD99_RS08670	COG4807	Protein conserved in bacteria
BMD99_RS08690	COG5455	response to cobalt ion
BMD99_RS08695	COG0583	DNA-binding transcription factor activity
BMD99_RS08700	COG2252	PERMEase
BMD99_RS08710	COG0583	DNA-binding transcription factor activity
BMD99_RS08715	COG2015	COG2015, Alkyl sulfatase and related hydrolases
BMD99_RS08725	COG2015	COG2015, Alkyl sulfatase and related hydrolases
BMD99_RS08735	COG0351	phosphomethylpyrimidine kinase
BMD99_RS08740	COG1830	Aldolase
BMD99_RS08755	COG1070	Carbohydrate kinase
BMD99_RS08765	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BMD99_RS08775	COG0826	peptidase U32
BMD99_RS08780	COG0745	RESPONSE REGULATOR receiver
BMD99_RS08785	COG2205	protein histidine kinase activity
BMD99_RS08810	COG1301	dicarboxylic acid transport
BMD99_RS08825	COG5002	protein histidine kinase activity
BMD99_RS08830	COG0443	Heat shock 70 kDa protein
BMD99_RS08835	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
BMD99_RS08850	COG2982	Protein involved in outer membrane biogenesis
BMD99_RS08855	COG1253	flavin adenine dinucleotide binding
BMD99_RS08950	COG1088	dTDP-glucose 4,6-dehydratase activity
BMD99_RS08960	COG1091	dTDP-4-dehydrorhamnose reductase activity
BMD99_RS08980	COG2244	polysaccharide biosynthetic process
BMD99_RS08985	COG1216	Glycosyl transferase, family 2
BMD99_RS08985	COG1442	glycosyl transferase family 8
BMD99_RS09020	COG3436	PFAM IS66 Orf2 family protein
BMD99_RS09090	COG0438	transferase activity, transferring glycosyl groups
BMD99_RS09095	COG1442	glycosyl transferase family 8
BMD99_RS09095	COG1216	Glycosyl transferase, family 2
BMD99_RS09105	COG0463	Glycosyl transferase, family 2
BMD99_RS09130	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
BMD99_RS09160	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BMD99_RS09165	COG0583	DNA-binding transcription factor activity
BMD99_RS09175	COG0531	amino acid
BMD99_RS09200	COG3604	Transcriptional regulator
BMD99_RS09205	COG2205	protein histidine kinase activity
BMD99_RS09290	COG0640	Transcriptional regulator
BMD99_RS09295	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
BMD99_RS09300	COG2925	Exonuclease
BMD99_RS09315	COG1289	transmembrane transporter activity
BMD99_RS09335	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
BMD99_RS09345	COG1942	4-Oxalocrotonate Tautomerase
BMD99_RS09350	COG0583	DNA-binding transcription factor activity
BMD99_RS09355	COG0095	Lipoate-protein ligase
BMD99_RS09360	COG0477	Major facilitator Superfamily
BMD99_RS09375	COG3300	MHYT domain
BMD99_RS09375	COG5001	Diguanylate cyclase
BMD99_RS09380	COG3615	Tellurite resistance protein tehB
BMD99_RS09405	COG3706	GGDEF domain
BMD99_RS09425	COG0534	Mate efflux family protein
BMD99_RS09440	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
BMD99_RS09460	COG0604	alcohol dehydrogenase
BMD99_RS09465	COG1309	transcriptional regulator
BMD99_RS09470	COG0025	NhaP-type Na H and K H
BMD99_RS09490	COG1376	ErfK ybiS ycfS ynhG family protein
BMD99_RS09520	COG1028	Short-chain dehydrogenase reductase Sdr
BMD99_RS09530	COG0523	cobalamin synthesis protein
BMD99_RS09590	COG3436	PFAM IS66 Orf2 family protein
BMD99_RS09595	COG4372	Transposase
BMD99_RS09610	COG0583	DNA-binding transcription factor activity
BMD99_RS09620	COG1028	Short-chain dehydrogenase reductase Sdr
BMD99_RS09625	COG1028	Short-chain dehydrogenase reductase Sdr
BMD99_RS09630	COG4221	oxidoreductase activity
BMD99_RS09635	COG2207	Transcriptional regulator
BMD99_RS09645	COG1959	2 iron, 2 sulfur cluster binding
BMD99_RS09655	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BMD99_RS09660	COG0582	viral genome integration into host DNA
BMD99_RS09680	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
BMD99_RS09695	COG1418	mRNA catabolic process
BMD99_RS09700	COG0270	DNA (cytosine-5-)-methyltransferase activity
BMD99_RS09705	COG3727	T/G mismatch-specific endonuclease activity
BMD99_RS09710	COG0697	spore germination
BMD99_RS09715	COG2354	Protein conserved in bacteria
BMD99_RS09745	COG0366	Alpha amylase catalytic
BMD99_RS09750	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BMD99_RS09760	COG0765	amino acid transport
BMD99_RS09765	COG1126	abc transporter atp-binding protein
BMD99_RS09770	COG2197	response regulator
BMD99_RS09780	COG2197	response regulator
BMD99_RS09820	COG3318	Belongs to the UPF0149 family
BMD99_RS09820	COG3012	SEC-C Motif Domain Protein
BMD99_RS09825	COG0814	amino acid
BMD99_RS09835	COG1528	Iron-storage protein
BMD99_RS09845	COG0477	Major facilitator Superfamily
BMD99_RS09855	COG2211	Major facilitator Superfamily
BMD99_RS09865	COG1528	Iron-storage protein
BMD99_RS09870	COG1879	ABC-type sugar transport system periplasmic component
BMD99_RS09880	COG1172	Belongs to the binding-protein-dependent transport system permease family
BMD99_RS09905	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
BMD99_RS09915	COG3102	Protein conserved in bacteria
BMD99_RS09935	COG3788	relative of glutathione S-transferase, MAPEG superfamily
BMD99_RS09940	COG1801	Protein of unknown function DUF72
BMD99_RS09945	COG1335	isochorismatase
BMD99_RS09955	COG0494	nUDIX hydrolase
BMD99_RS09980	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BMD99_RS09990	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
BMD99_RS09995	COG0739	heme binding
BMD99_RS10000	COG1560	Kdo2-lipid A biosynthetic process
BMD99_RS10010	COG1737	Transcriptional regulator
BMD99_RS10020	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
BMD99_RS10025	COG0129	dihydroxy-acid dehydratase activity
BMD99_RS10030	COG0800	Aldolase
BMD99_RS10040	COG3141	response to X-ray
BMD99_RS10045	COG2979	Protein of unknown function (DUF533)
BMD99_RS10050	COG1770	oligopeptidase
BMD99_RS10055	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
BMD99_RS10065	COG2372	response to copper ion
BMD99_RS10070	COG1276	copper resistance
BMD99_RS10080	COG1216	Glycosyl transferase, family 2
BMD99_RS10080	COG1442	glycosyl transferase family 8
BMD99_RS10125	COG3008	intermembrane lipid transfer
BMD99_RS10130	COG2995	paraquat-inducible protein a
BMD99_RS10135	COG1956	GAF domain-containing protein
BMD99_RS10155	COG2814	Major facilitator Superfamily
BMD99_RS10165	COG1414	Transcriptional regulator
BMD99_RS10205	COG0768	penicillin binding
BMD99_RS10210	COG2226	methyltransferase
BMD99_RS10225	COG3716	PTS system mannose fructose sorbose family IID component
BMD99_RS10230	COG3715	PTS system
BMD99_RS10235	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BMD99_RS10235	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
BMD99_RS10240	COG1253	flavin adenine dinucleotide binding
BMD99_RS10245	COG2200	EAL domain
BMD99_RS10250	COG1760	l-serine dehydratase
BMD99_RS10270	COG0251	oxidation-reduction process
BMD99_RS10275	COG1199	ATP-dependent helicase activity
BMD99_RS10280	COG1214	PFAM Peptidase M22, glycoprotease
BMD99_RS10285	COG3065	identical protein binding
BMD99_RS10295	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
BMD99_RS10305	COG2894	cell division
BMD99_RS10320	COG0179	Fumarylacetoacetate (FAA) hydrolase
BMD99_RS10350	COG2719	SpoVR family
BMD99_RS10370	COG1619	proteins homologs of microcin C7 resistance protein MccF
BMD99_RS10390	COG4774	siderophore transport
BMD99_RS10405	COG2308	Evidence 4 Homologs of previously reported genes of
BMD99_RS10435	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BMD99_RS10445	COG1174	glycine betaine transport
BMD99_RS10460	COG0583	DNA-binding transcription factor activity
BMD99_RS10465	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
BMD99_RS10480	COG1882	Formate acetyltransferase
BMD99_RS10510	COG0583	DNA-binding transcription factor activity
BMD99_RS10535	COG0583	DNA-binding transcription factor activity
BMD99_RS10550	COG3122	Protein conserved in bacteria
BMD99_RS10575	COG2885	chlorophyll binding
BMD99_RS10595	COG1262	PFAM Formylglycine-generating sulfatase enzyme
BMD99_RS10600	COG1262	PFAM Formylglycine-generating sulfatase enzyme
BMD99_RS10735	COG1396	sequence-specific DNA binding
BMD99_RS10750	COG2003	Belongs to the UPF0758 family
BMD99_RS10755	COG4974	Belongs to the 'phage' integrase family
BMD99_RS10785	COG1196	nuclear chromosome segregation
BMD99_RS10820	COG0582	viral genome integration into host DNA
BMD99_RS10825	COG0012	GTP binding
BMD99_RS10845	COG0659	secondary active sulfate transmembrane transporter activity
BMD99_RS10875	COG2890	protein-(glutamine-N5) methyltransferase activity
BMD99_RS10895	COG0387	Pfam Sodium calcium exchanger
BMD99_RS10900	COG4572	Cation transport regulator
BMD99_RS10905	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
BMD99_RS10915	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
BMD99_RS10920	COG3707	response regulator
BMD99_RS10925	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BMD99_RS10935	COG1116	anion transmembrane transporter activity
BMD99_RS10940	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BMD99_RS10940	COG2146	nitrite reductase [NAD(P)H] activity
BMD99_RS10945	COG0243	molybdopterin cofactor binding
BMD99_RS10950	COG4932	domain protein
BMD99_RS10955	COG2197	response regulator
BMD99_RS10960	COG3850	Histidine kinase
BMD99_RS10970	COG2223	nitrite transmembrane transporter activity
BMD99_RS10975	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
BMD99_RS10980	COG1140	nitrate reductase beta subunit
BMD99_RS10985	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
BMD99_RS10990	COG2181	nitrate reductase activity
BMD99_RS11000	COG1522	sequence-specific DNA binding
BMD99_RS11025	COG0788	formyltetrahydrofolate deformylase activity
BMD99_RS11035	COG1752	Esterase of the alpha-beta hydrolase superfamily
BMD99_RS11040	COG0745	RESPONSE REGULATOR receiver
BMD99_RS11045	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BMD99_RS11050	COG2916	Histone family protein nucleoid-structuring protein H-NS
BMD99_RS11055	COG1435	thymidine kinase activity
BMD99_RS11060	COG1012	belongs to the aldehyde dehydrogenase family
BMD99_RS11060	COG1454	alcohol dehydrogenase
BMD99_RS11065	COG2095	MarC family integral membrane protein
BMD99_RS11070	COG4166	transmembrane transport
BMD99_RS11075	COG0601	transmembrane transport
BMD99_RS11080	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BMD99_RS11085	COG0444	Belongs to the ABC transporter superfamily
BMD99_RS11095	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BMD99_RS11115	COG2353	YceI-like domain
BMD99_RS11120	COG2350	Protein conserved in bacteria
BMD99_RS11130	COG3001	Fructosamine kinase
BMD99_RS11140	COG1105	Belongs to the carbohydrate kinase PfkB family
BMD99_RS11145	COG3137	Salt-induced outer membrane protein
BMD99_RS11185	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BMD99_RS11185	COG0072	phenylalanine-tRNA ligase activity
BMD99_RS11205	COG0583	DNA-binding transcription factor activity
BMD99_RS11225	COG0386	Belongs to the glutathione peroxidase family
BMD99_RS11235	COG0791	NLP P60 protein
BMD99_RS11245	COG4256	Hemin uptake protein
BMD99_RS11250	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
BMD99_RS11260	COG0574	Belongs to the PEP-utilizing enzyme family
BMD99_RS11260	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BMD99_RS11270	COG0628	permease
BMD99_RS11275	COG0277	FAD linked oxidase domain protein
BMD99_RS11275	COG0247	lactate metabolic process
BMD99_RS11280	COG2050	protein possibly involved in aromatic compounds catabolism
BMD99_RS11285	COG2261	transglycosylase associated protein
BMD99_RS11310	COG0583	DNA-binding transcription factor activity
BMD99_RS11335	COG1304	FMN binding
BMD99_RS11350	COG0316	Belongs to the HesB IscA family
BMD99_RS11355	COG0719	Fe-S assembly protein
BMD99_RS11360	COG0396	ATPase activity
BMD99_RS11365	COG0719	Fe-S assembly protein
BMD99_RS11380	COG1376	ErfK ybiS ycfS ynhG family protein
BMD99_RS11405	COG1309	transcriptional regulator
BMD99_RS11410	COG3185	4-Hydroxyphenylpyruvate dioxygenase
BMD99_RS11410	COG1082	Xylose isomerase domain protein TIM barrel
BMD99_RS11415	COG2271	Major facilitator Superfamily
BMD99_RS11420	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
BMD99_RS11430	COG1120	ATPase activity
BMD99_RS11435	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BMD99_RS11440	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BMD99_RS11445	COG1414	Transcriptional regulator
BMD99_RS11480	COG2814	Major facilitator Superfamily
BMD99_RS11500	COG0583	DNA-binding transcription factor activity
BMD99_RS11505	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BMD99_RS11525	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BMD99_RS11530	COG1116	anion transmembrane transporter activity
BMD99_RS11535	COG4774	siderophore transport
BMD99_RS11540	COG1120	ATPase activity
BMD99_RS11545	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BMD99_RS11550	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BMD99_RS11570	COG0765	amino acid transport
BMD99_RS11575	COG1126	abc transporter atp-binding protein
BMD99_RS11595	COG1473	amidohydrolase
BMD99_RS11600	COG3383	formate dehydrogenase (NAD+) activity
BMD99_RS11605	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
BMD99_RS11620	COG1175	transmembrane transport
BMD99_RS11650	COG1857	crispr-associated protein
BMD99_RS11660	COG1518	maintenance of DNA repeat elements
BMD99_RS11665	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
BMD99_RS11670	COG3157	Type VI secretion system effector, Hcp
BMD99_RS11700	COG4133	protoheme IX ABC transporter activity
BMD99_RS11705	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BMD99_RS11710	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BMD99_RS11725	COG1138	Cytochrome C-type biogenesis protein
BMD99_RS11730	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BMD99_RS11735	COG3088	subunit of a heme lyase
BMD99_RS11735	COG4235	cytochrome complex assembly
BMD99_RS11770	COG1028	Short-chain dehydrogenase reductase Sdr
BMD99_RS11775	COG2610	gluconate transmembrane transporter activity
BMD99_RS11780	COG1250	3-hydroxyacyl-CoA dehydrogenase
BMD99_RS11790	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
BMD99_RS11800	COG0583	DNA-binding transcription factor activity
BMD99_RS11850	COG0277	FAD linked oxidase domain protein
BMD99_RS11855	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BMD99_RS11880	COG0402	S-adenosylhomocysteine deaminase activity
BMD99_RS11970	COG0604	alcohol dehydrogenase
BMD99_RS11970	COG1028	Short-chain dehydrogenase reductase Sdr
BMD99_RS11970	COG3321	synthase
BMD99_RS11975	COG0583	DNA-binding transcription factor activity
BMD99_RS12000	COG4608	Belongs to the ABC transporter superfamily
BMD99_RS12005	COG0444	Belongs to the ABC transporter superfamily
BMD99_RS12035	COG2011	ABC-type metal ion transport system permease component
BMD99_RS12050	COG0346	lactoylglutathione lyase activity
BMD99_RS12055	COG1349	DNA-binding transcription factor activity
BMD99_RS12085	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BMD99_RS12105	COG0300	oxidoreductase activity
BMD99_RS12150	COG0307	riboflavin synthase, alpha
BMD99_RS12155	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
BMD99_RS12160	COG2814	Major facilitator Superfamily
BMD99_RS12165	COG0583	DNA-binding transcription factor activity
BMD99_RS12180	COG2814	Major facilitator Superfamily
BMD99_RS12190	COG2207	Transcriptional regulator
BMD99_RS12195	COG0791	NLP P60 protein
BMD99_RS12200	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
BMD99_RS12210	COG0346	lactoylglutathione lyase activity
BMD99_RS12215	COG1902	pentaerythritol trinitrate reductase activity
BMD99_RS12220	COG1309	transcriptional regulator
BMD99_RS12225	COG3313	Fe-S protein
BMD99_RS12230	COG4989	oxidoreductase activity
BMD99_RS12235	COG2032	superoxide dismutase activity
BMD99_RS12240	COG1289	transmembrane transporter activity
BMD99_RS12245	COG1566	PFAM secretion protein HlyD family protein
BMD99_RS12265	COG3335	DDE superfamily endonuclease
BMD99_RS12285	COG3895	Periplasmic Protein
BMD99_RS12300	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
BMD99_RS12305	COG0625	glutathione transferase activity
BMD99_RS12320	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
BMD99_RS12330	COG4659	FMN binding
BMD99_RS12365	COG2723	6-phospho-beta-galactosidase activity
BMD99_RS12375	COG0673	inositol 2-dehydrogenase activity
BMD99_RS12395	COG3038	cytochrome b561
BMD99_RS12415	COG0583	DNA-binding transcription factor activity
BMD99_RS12420	COG3485	protocatechuate 3,4-dioxygenase
BMD99_RS12425	COG3485	protocatechuate 3,4-dioxygenase
BMD99_RS12430	COG5383	Protein conserved in bacteria
BMD99_RS12435	COG2272	Belongs to the type-B carboxylesterase lipase family
BMD99_RS12450	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BMD99_RS12455	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
BMD99_RS12460	COG1275	C4-dicarboxylate transporter malic acid transport protein
BMD99_RS12465	COG0500	methyltransferase
BMD99_RS12480	COG2207	Transcriptional regulator
BMD99_RS12480	COG3708	Transcriptional regulator
BMD99_RS12485	COG3135	benzoate transporter
BMD99_RS12490	COG1396	sequence-specific DNA binding
BMD99_RS12495	COG0826	peptidase U32
BMD99_RS12515	COG1294	oxidase, subunit
BMD99_RS12520	COG1271	oxidase subunit
BMD99_RS12525	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BMD99_RS12530	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
BMD99_RS12535	COG3842	ATPase activity
BMD99_RS12540	COG1176	ABC-type spermidine putrescine transport system, permease component I
BMD99_RS12545	COG1177	transmembrane transport
BMD99_RS12550	COG1012	belongs to the aldehyde dehydrogenase family
BMD99_RS12575	COG1012	belongs to the aldehyde dehydrogenase family
BMD99_RS12585	COG0747	negative chemotaxis
BMD99_RS12595	COG3238	Protein conserved in bacteria
BMD99_RS12600	COG1247	-acetyltransferase
BMD99_RS12610	COG2130	NADP-dependent
BMD99_RS12620	COG3691	Protein conserved in bacteria
BMD99_RS12630	COG4772	TonB-dependent receptor
BMD99_RS12655	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
BMD99_RS12660	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
BMD99_RS12665	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
BMD99_RS12670	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BMD99_RS12675	COG1473	amidohydrolase
BMD99_RS12680	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BMD99_RS12685	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BMD99_RS12695	COG0765	amino acid transport
BMD99_RS12700	COG1126	abc transporter atp-binding protein
BMD99_RS12710	COG2271	Major facilitator Superfamily
BMD99_RS12720	COG1609	Transcriptional regulator
BMD99_RS12725	COG0625	glutathione transferase activity
BMD99_RS12740	COG2211	Major facilitator Superfamily
BMD99_RS12755	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BMD99_RS12760	COG3842	ATPase activity
BMD99_RS12765	COG1840	ABC-type Fe3 transport system, periplasmic component
BMD99_RS12770	COG1178	ABC-type Fe3 transport system permease component
BMD99_RS12775	COG2162	N-hydroxyarylamine O-acetyltransferase activity
BMD99_RS12790	COG3335	DDE superfamily endonuclease
BMD99_RS12805	COG2181	nitrate reductase activity
BMD99_RS12810	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
BMD99_RS12815	COG1140	nitrate reductase beta subunit
BMD99_RS12820	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
BMD99_RS12840	COG1414	Transcriptional regulator
BMD99_RS12845	COG4948	Mandelate Racemase Muconate Lactonizing
BMD99_RS12850	COG4829	muconolactone delta-isomerase
BMD99_RS12855	COG3485	protocatechuate 3,4-dioxygenase
BMD99_RS12865	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
BMD99_RS12880	COG0697	spore germination
BMD99_RS12885	COG0243	molybdopterin cofactor binding
BMD99_RS12885	COG3383	formate dehydrogenase (NAD+) activity
BMD99_RS12890	COG3383	formate dehydrogenase (NAD+) activity
BMD99_RS12890	COG0243	molybdopterin cofactor binding
BMD99_RS12895	COG0437	4 iron, 4 sulfur cluster binding
BMD99_RS12900	COG2864	formate dehydrogenase
BMD99_RS12915	COG2326	polyphosphate kinase activity
BMD99_RS12925	COG2814	Major facilitator Superfamily
BMD99_RS12935	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BMD99_RS12945	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BMD99_RS12950	COG0601	transmembrane transport
BMD99_RS12955	COG0747	negative chemotaxis
BMD99_RS12960	COG1064	alcohol dehydrogenase
BMD99_RS12975	COG0488	(ABC) transporter
BMD99_RS13020	COG1028	Short-chain dehydrogenase reductase Sdr
BMD99_RS13025	COG3729	General stress protein
BMD99_RS13035	COG3685	Protein conserved in bacteria
BMD99_RS13055	COG2323	membrane
BMD99_RS13065	COG3111	PFAM Bacterial OB fold (BOF) protein
BMD99_RS13070	COG1764	response to oxidative stress
BMD99_RS13090	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
BMD99_RS13095	COG3781	membrane
BMD99_RS13100	COG0243	molybdopterin cofactor binding
BMD99_RS13105	COG0583	DNA-binding transcription factor activity
BMD99_RS13110	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BMD99_RS13140	COG1447	Phosphotransferase system cellobiose-specific component IIA
BMD99_RS13145	COG2814	Major facilitator Superfamily
BMD99_RS13150	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
BMD99_RS13160	COG0583	DNA-binding transcription factor activity
BMD99_RS13180	COG0519	Catalyzes the synthesis of GMP from XMP
BMD99_RS13180	COG0518	GMP synthase (glutamine-hydrolyzing) activity
BMD99_RS13220	COG0596	Alpha beta hydrolase
BMD99_RS13230	COG2205	protein histidine kinase activity
BMD99_RS13245	COG0076	glutamate decarboxylase activity
BMD99_RS13250	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
BMD99_RS13255	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BMD99_RS13260	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BMD99_RS13265	COG1116	anion transmembrane transporter activity
BMD99_RS13270	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
BMD99_RS13295	COG4644	lycopene metabolic process
BMD99_RS13310	COG1609	Transcriptional regulator
BMD99_RS13315	COG3706	GGDEF domain
BMD99_RS13325	COG0402	S-adenosylhomocysteine deaminase activity
BMD99_RS13330	COG1953	Uracil, thiamine, allantoin
BMD99_RS13365	COG0406	alpha-ribazole phosphatase activity
BMD99_RS13370	COG1280	lysine exporter protein (LysE YggA)
BMD99_RS13395	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BMD99_RS13460	COG0765	amino acid transport
BMD99_RS13470	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
BMD99_RS13480	COG2070	2-Nitropropane dioxygenase
BMD99_RS13485	COG0583	DNA-binding transcription factor activity
BMD99_RS13495	COG1902	pentaerythritol trinitrate reductase activity
BMD99_RS13500	COG4529	Protein conserved in bacteria
BMD99_RS13505	COG0477	Major facilitator Superfamily
BMD99_RS13535	COG2223	nitrite transmembrane transporter activity
BMD99_RS13545	COG1609	Transcriptional regulator
BMD99_RS13565	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
BMD99_RS13575	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BMD99_RS13600	COG3655	Transcriptional regulator
BMD99_RS13635	COG0583	DNA-binding transcription factor activity
BMD99_RS13640	COG1979	alcohol dehydrogenase
BMD99_RS13645	COG1028	Short-chain dehydrogenase reductase Sdr
BMD99_RS13660	COG4977	sequence-specific DNA binding
BMD99_RS13675	COG5002	protein histidine kinase activity
BMD99_RS13675	COG3850	Histidine kinase
BMD99_RS13710	COG2186	Transcriptional regulator
BMD99_RS13715	COG1263	PTS System
BMD99_RS13715	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BMD99_RS13725	COG2814	Major facilitator Superfamily
BMD99_RS13730	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
BMD99_RS13730	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BMD99_RS13745	COG2819	hydrolase of the alpha beta superfamily
BMD99_RS13785	COG3188	usher protein
BMD99_RS13795	COG1649	PFAM Uncharacterised BCR, COG1649
BMD99_RS13800	COG3550	peptidyl-serine autophosphorylation
BMD99_RS13805	COG1396	sequence-specific DNA binding
BMD99_RS13810	COG2351	hydroxyisourate hydrolase activity
BMD99_RS13815	COG3195	allantoin biosynthetic process
BMD99_RS13815	COG3648	Uricase
BMD99_RS13820	COG2233	PERMEase
BMD99_RS13850	COG2207	Transcriptional regulator
BMD99_RS13865	COG4628	conserved protein (DUF2132)
BMD99_RS13885	COG2011	ABC-type metal ion transport system permease component
BMD99_RS13890	COG2070	2-Nitropropane dioxygenase
BMD99_RS13970	COG2199	diguanylate cyclase activity
BMD99_RS13985	COG1012	belongs to the aldehyde dehydrogenase family
BMD99_RS13990	COG0583	DNA-binding transcription factor activity
BMD99_RS14000	COG0039	L-malate dehydrogenase activity
BMD99_RS14005	COG1349	DNA-binding transcription factor activity
BMD99_RS14010	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
BMD99_RS14015	COG3395	kinase activity
BMD99_RS14020	COG1454	alcohol dehydrogenase
BMD99_RS14025	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BMD99_RS14030	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BMD99_RS14035	COG2271	Major facilitator Superfamily
BMD99_RS14060	COG4977	sequence-specific DNA binding
BMD99_RS14070	COG0697	spore germination
BMD99_RS14075	COG2814	Major facilitator Superfamily
BMD99_RS14090	COG1129	ABC transporter
BMD99_RS14105	COG0683	leucine binding
BMD99_RS14110	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
BMD99_RS14145	COG2223	nitrite transmembrane transporter activity
BMD99_RS14150	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
BMD99_RS14165	COG1349	DNA-binding transcription factor activity
BMD99_RS14170	COG2084	Dehydrogenase
BMD99_RS14175	COG3395	kinase activity
BMD99_RS14180	COG0235	Class ii aldolase
BMD99_RS14185	COG3622	Belongs to the hyi family
BMD99_RS14190	COG2610	gluconate transmembrane transporter activity
BMD99_RS14210	COG2200	EAL domain
BMD99_RS14215	COG1546	Belongs to the CinA family
BMD99_RS14220	COG0071	Belongs to the small heat shock protein (HSP20) family
BMD99_RS14240	COG4221	oxidoreductase activity
BMD99_RS14245	COG1802	Transcriptional regulator
BMD99_RS14250	COG0589	response to stress
BMD99_RS14255	COG0246	Mannitol dehydrogenase
BMD99_RS14260	COG2271	Major facilitator Superfamily
BMD99_RS14275	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BMD99_RS14290	COG0243	molybdopterin cofactor binding
BMD99_RS14295	COG0437	4 iron, 4 sulfur cluster binding
BMD99_RS14300	COG3302	dmso reductase anchor subunit
BMD99_RS14315	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
BMD99_RS14320	COG1940	carbohydrate kinase activity
BMD99_RS14325	COG0583	DNA-binding transcription factor activity
BMD99_RS14330	COG2814	Major facilitator Superfamily
BMD99_RS14335	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
BMD99_RS14350	COG3591	Belongs to the peptidase S1B family
BMD99_RS14365	COG0628	permease
BMD99_RS14395	COG0679	Auxin Efflux Carrier
BMD99_RS14405	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
BMD99_RS14415	COG2814	Major facilitator Superfamily
BMD99_RS14430	COG3290	protein histidine kinase activity
BMD99_RS14435	COG4565	transcriptional regulatory protein
BMD99_RS14460	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
BMD99_RS14460	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
BMD99_RS14480	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BMD99_RS14485	COG0596	Alpha beta hydrolase
BMD99_RS14495	COG0183	Belongs to the thiolase family
BMD99_RS14500	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
BMD99_RS14510	COG1414	Transcriptional regulator
BMD99_RS14515	COG2840	Smr protein MutS2
BMD99_RS14520	COG0583	DNA-binding transcription factor activity
BMD99_RS14530	COG1473	amidohydrolase
BMD99_RS14535	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
BMD99_RS14545	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BMD99_RS14550	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BMD99_RS14565	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
BMD99_RS14570	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
BMD99_RS14590	COG0531	amino acid
BMD99_RS14600	COG3136	membrane protein required for alginate biosynthesis
BMD99_RS14605	COG0745	RESPONSE REGULATOR receiver
BMD99_RS14615	COG2205	protein histidine kinase activity
BMD99_RS14625	COG0114	fumarate hydratase activity
BMD99_RS14630	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
BMD99_RS14630	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
BMD99_RS14635	COG1482	cell wall glycoprotein biosynthetic process
BMD99_RS14640	COG5339	Protein conserved in bacteria
BMD99_RS14645	COG1609	Transcriptional regulator
BMD99_RS14650	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BMD99_RS14650	COG1263	PTS System
BMD99_RS14655	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
BMD99_RS14675	COG2391	methyltransferase activity
BMD99_RS14680	COG0425	Belongs to the sulfur carrier protein TusA family
BMD99_RS14685	COG5562	phage envelope protein
BMD99_RS14690	COG0401	homolog of Blt101
BMD99_RS14695	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
BMD99_RS14700	COG1012	belongs to the aldehyde dehydrogenase family
BMD99_RS14710	COG1434	Gram-negative-bacterium-type cell wall biogenesis
BMD99_RS14715	COG0477	Major facilitator Superfamily
BMD99_RS14720	COG1113	amino acid transport
BMD99_RS14725	COG2988	succinylglutamate desuccinylase activity
BMD99_RS14730	COG3724	N-succinylarginine dihydrolase activity
BMD99_RS14735	COG1012	belongs to the aldehyde dehydrogenase family
BMD99_RS14740	COG3138	arginine N-succinyltransferase
BMD99_RS14745	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BMD99_RS14750	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BMD99_RS14755	COG0667	Aldo Keto reductase
BMD99_RS14760	COG0583	DNA-binding transcription factor activity
BMD99_RS14785	COG4122	O-methyltransferase activity
BMD99_RS14795	COG3335	DDE superfamily endonuclease
BMD99_RS14810	COG1643	Atp-dependent helicase
BMD99_RS14820	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system
BMD99_RS14830	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
BMD99_RS14835	COG3327	negative regulation of DNA-templated transcription, initiation
BMD99_RS14840	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
BMD99_RS14845	COG0183	Belongs to the thiolase family
BMD99_RS14850	COG2050	protein possibly involved in aromatic compounds catabolism
BMD99_RS14855	COG1250	3-hydroxyacyl-CoA dehydrogenase
BMD99_RS14860	COG1024	Enoyl-CoA hydratase
BMD99_RS14865	COG1024	Enoyl-CoA hydratase
BMD99_RS14870	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BMD99_RS14875	COG2151	metal-sulfur cluster biosynthetic enzyme
BMD99_RS14880	COG3396	Phenylacetate-CoA oxygenase
BMD99_RS14885	COG3460	Phenylacetate-CoA oxygenase
BMD99_RS14890	COG3396	Phenylacetate-CoA oxygenase
BMD99_RS14895	COG2030	dehydratase
BMD99_RS14895	COG1012	belongs to the aldehyde dehydrogenase family
BMD99_RS14920	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BMD99_RS14935	COG2072	flavoprotein involved in K transport
BMD99_RS14940	COG0583	DNA-binding transcription factor activity
BMD99_RS14945	COG1126	abc transporter atp-binding protein
BMD99_RS14955	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BMD99_RS14970	COG1012	belongs to the aldehyde dehydrogenase family
BMD99_RS14975	COG2207	Transcriptional regulator
BMD99_RS14980	COG3784	Protein of unknown function (DUF1318)
BMD99_RS14990	COG2911	Protein conserved in bacteria
BMD99_RS15000	COG0586	Pfam SNARE associated Golgi protein
BMD99_RS15005	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BMD99_RS15010	COG3187	Heat shock protein
BMD99_RS15015	COG3042	response to heat
BMD99_RS15025	COG1013	pyruvate-flavodoxin oxidoreductase activity
BMD99_RS15025	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
BMD99_RS15025	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BMD99_RS15025	COG0674	pyruvate-flavodoxin oxidoreductase activity
BMD99_RS15030	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
BMD99_RS15050	COG0513	Belongs to the DEAD box helicase family
BMD99_RS15065	COG1349	DNA-binding transcription factor activity
BMD99_RS15070	COG0673	inositol 2-dehydrogenase activity
BMD99_RS15085	COG2011	ABC-type metal ion transport system permease component
BMD99_RS15090	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
BMD99_RS15095	COG1464	Belongs to the NlpA lipoprotein family
BMD99_RS15100	COG0436	Aminotransferase
BMD99_RS15105	COG0604	alcohol dehydrogenase
BMD99_RS15130	COG0583	DNA-binding transcription factor activity
BMD99_RS15150	COG1028	Short-chain dehydrogenase reductase Sdr
BMD99_RS15155	COG1309	transcriptional regulator
BMD99_RS15160	COG1028	Short-chain dehydrogenase reductase Sdr
BMD99_RS15255	COG2885	chlorophyll binding
BMD99_RS15280	COG0693	protein deglycase activity
BMD99_RS15285	COG1078	dGTPase activity
BMD99_RS15290	COG1028	Short-chain dehydrogenase reductase Sdr
BMD99_RS15295	COG0583	DNA-binding transcription factor activity
BMD99_RS15330	COG5002	protein histidine kinase activity
BMD99_RS15330	COG0784	Response regulator, receiver
BMD99_RS15330	COG2205	protein histidine kinase activity
BMD99_RS15335	COG0656	L-ascorbic acid biosynthetic process
BMD99_RS15365	COG4166	transmembrane transport
BMD99_RS15370	COG2866	Carboxypeptidase
BMD99_RS15375	COG4948	Mandelate Racemase Muconate Lactonizing
BMD99_RS15380	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
BMD99_RS15385	COG3180	Ammonia monooxygenase
BMD99_RS15395	COG1486	melibiose metabolic process
BMD99_RS15400	COG0583	DNA-binding transcription factor activity
BMD99_RS15410	COG3106	COG3106 Predicted ATPase
BMD99_RS15420	COG1983	PspC domain protein
BMD99_RS15430	COG1842	Phage shock protein A
BMD99_RS15435	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
BMD99_RS15445	COG1473	amidohydrolase
BMD99_RS15460	COG0702	epimerase
BMD99_RS15475	COG4171	peptide transport system, permease
BMD99_RS15490	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
BMD99_RS15505	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BMD99_RS15505	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BMD99_RS15520	COG1349	DNA-binding transcription factor activity
BMD99_RS15530	COG0023	Translation Initiation Factor
BMD99_RS15540	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
BMD99_RS15545	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
BMD99_RS15550	COG0671	phosphoesterase, PA-phosphatase related
BMD99_RS15560	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
BMD99_RS15585	COG0616	signal peptide processing
BMD99_RS15595	COG1028	Short-chain dehydrogenase reductase Sdr
BMD99_RS15600	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
BMD99_RS15620	COG0009	L-threonylcarbamoyladenylate synthase
BMD99_RS15630	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
BMD99_RS15635	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
BMD99_RS15635	COG0512	Glutamine amidotransferase of anthranilate synthase
BMD99_RS15640	COG0134	indole-3-glycerol-phosphate synthase activity
BMD99_RS15640	COG0135	phosphoribosylanthranilate isomerase activity
BMD99_RS15685	COG4774	siderophore transport
BMD99_RS15695	COG3047	cAMP biosynthetic process
BMD99_RS15700	COG0727	PFAM Uncharacterised protein family (UPF0153)
BMD99_RS15730	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BMD99_RS15735	COG1028	Short-chain dehydrogenase reductase Sdr
BMD99_RS15740	COG1988	membrane-bound metal-dependent
BMD99_RS15745	COG1823	symporter activity
BMD99_RS15755	COG0753	catalase activity
BMD99_RS15765	COG1486	melibiose metabolic process
BMD99_RS15770	COG1917	Cupin 2, conserved barrel domain protein
BMD99_RS15770	COG2169	Transcriptional regulator
BMD99_RS15775	COG1447	Phosphotransferase system cellobiose-specific component IIA
BMD99_RS15780	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BMD99_RS15785	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BMD99_RS15790	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BMD99_RS15800	COG0322	excinuclease ABC activity
BMD99_RS15805	COG3678	ATP-independent chaperone mediated protein folding
BMD99_RS15815	COG3724	N-succinylarginine dihydrolase activity
BMD99_RS15825	COG3138	arginine N-succinyltransferase
BMD99_RS15835	COG0708	Exodeoxyribonuclease III
BMD99_RS15840	COG0398	Pfam SNARE associated Golgi protein
BMD99_RS15845	COG0398	Pfam SNARE associated Golgi protein
BMD99_RS15850	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BMD99_RS15855	COG4134	Bacterial extracellular solute-binding protein
BMD99_RS15860	COG4135	transport system, permease component
BMD99_RS15865	COG4136	ATPase activity
BMD99_RS15870	COG2897	thiosulfate sulfurtransferase activity
BMD99_RS15875	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
BMD99_RS15880	COG0494	nUDIX hydrolase
BMD99_RS15890	COG3321	synthase
BMD99_RS15890	COG0604	alcohol dehydrogenase
BMD99_RS15890	COG1028	Short-chain dehydrogenase reductase Sdr
BMD99_RS15895	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BMD99_RS15900	COG0709	Synthesizes selenophosphate from selenide and ATP
BMD99_RS15910	COG0778	Nitroreductase
BMD99_RS15915	COG0616	signal peptide processing
BMD99_RS15920	COG0252	asparaginase activity
BMD99_RS15925	COG1335	isochorismatase
BMD99_RS15940	COG3139	Protein of unknown function (DUF1315)
BMD99_RS15960	COG0656	L-ascorbic acid biosynthetic process
BMD99_RS15965	COG3713	MltA-interacting MipA family protein
BMD99_RS15970	COG2766	serine protein kinase
BMD99_RS15985	COG0386	Belongs to the glutathione peroxidase family
BMD99_RS16010	COG1126	abc transporter atp-binding protein
BMD99_RS16015	COG0765	amino acid transport
BMD99_RS16020	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BMD99_RS16030	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BMD99_RS16040	COG1028	Short-chain dehydrogenase reductase Sdr
BMD99_RS16045	COG0583	DNA-binding transcription factor activity
BMD99_RS16050	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BMD99_RS16055	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
BMD99_RS16060	COG3344	reverse transcriptase
BMD99_RS16075	COG0859	PFAM glycosyl transferase family 9
BMD99_RS16080	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
BMD99_RS16090	COG2207	Transcriptional regulator
BMD99_RS16095	COG2807	transmembrane transport
BMD99_RS16100	COG0504	CTP synthase activity
BMD99_RS16105	COG1683	Conserved Protein
BMD99_RS16110	COG3189	MarR family transcriptional regulator
BMD99_RS16115	COG3042	response to heat
BMD99_RS16120	COG2203	Gaf domain
BMD99_RS16120	COG2199	diguanylate cyclase activity
BMD99_RS16140	COG3182	Iron-regulated membrane protein
BMD99_RS16150	COG1560	Kdo2-lipid A biosynthetic process
BMD99_RS16160	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
BMD99_RS16165	COG3706	GGDEF domain
BMD99_RS16170	COG0583	DNA-binding transcription factor activity
BMD99_RS16175	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
BMD99_RS16200	COG1294	oxidase, subunit
BMD99_RS16205	COG1271	oxidase subunit
BMD99_RS16210	COG3546	catalase activity
BMD99_RS16215	COG3685	Protein conserved in bacteria
BMD99_RS16225	COG3729	General stress protein
BMD99_RS16230	COG1063	alcohol dehydrogenase
BMD99_RS16235	COG3813	Protein conserved in bacteria
BMD99_RS16250	COG0640	Transcriptional regulator
BMD99_RS16265	COG3344	reverse transcriptase
BMD99_RS16390	COG4695	Portal protein
BMD99_RS16400	COG1802	Transcriptional regulator
BMD99_RS16400	COG4626	Terminase
BMD99_RS16435	COG3179	chitinase
BMD99_RS16455	COG3385	transposase activity
BMD99_RS16475	COG1403	HNH endonuclease
BMD99_RS16480	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
BMD99_RS16510	COG4197	protein conserved in bacteria, prophage-related
BMD99_RS16565	COG0582	viral genome integration into host DNA
BMD99_RS16570	COG0538	isocitrate dehydrogenase activity
BMD99_RS16575	COG1187	pseudouridine synthase activity
BMD99_RS16595	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
BMD99_RS16615	COG2205	protein histidine kinase activity
BMD99_RS16620	COG2850	peptidyl-arginine hydroxylation
BMD99_RS16625	COG1943	Transposase
BMD99_RS16645	COG1177	transmembrane transport
BMD99_RS16660	COG0318	PFAM AMP-dependent synthetase and ligase
BMD99_RS16665	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
BMD99_RS16670	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
BMD99_RS16675	COG0698	ribose 5-phosphate isomerase
BMD99_RS16690	COG3395	kinase activity
BMD99_RS16705	COG2390	Transcriptional regulator
BMD99_RS16715	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
BMD99_RS16725	COG4591	ABC-type transport system involved in lipoprotein release permease component
BMD99_RS16735	COG4591	ABC-type transport system involved in lipoprotein release permease component
BMD99_RS16740	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
BMD99_RS16745	COG1388	LysM domain
BMD99_RS16745	COG1376	ErfK ybiS ycfS ynhG family protein
BMD99_RS16755	COG1309	transcriptional regulator
BMD99_RS16765	COG3134	Outer membrane lipoprotein
BMD99_RS16770	COG1252	NADH dehydrogenase
BMD99_RS16800	COG5633	Lipoprotein
BMD99_RS16805	COG0537	adenosine 5'-monophosphoramidase activity
BMD99_RS16815	COG0084	hydrolase, TatD family'
BMD99_RS16820	COG0470	DNA polymerase III
BMD99_RS16830	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
BMD99_RS16835	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BMD99_RS16840	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BMD99_RS16850	COG1028	Short-chain dehydrogenase reductase Sdr
BMD99_RS16855	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
BMD99_RS16875	COG1399	metal-binding, possibly nucleic acid-binding protein
BMD99_RS16880	COG0424	maF-like protein
BMD99_RS16895	COG1530	ribonuclease E activity
BMD99_RS16900	COG0583	DNA-binding transcription factor activity
BMD99_RS16905	COG2814	Major facilitator Superfamily
BMD99_RS16925	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BMD99_RS16975	COG1560	Kdo2-lipid A biosynthetic process
BMD99_RS16995	COG5645	(Lipo)protein
BMD99_RS17035	COG3381	protein complex oligomerization
BMD99_RS17055	COG0583	DNA-binding transcription factor activity
BMD99_RS17065	COG1335	isochorismatase
BMD99_RS17080	COG1702	phosphate starvation-inducible protein PhoH
BMD99_RS17100	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BMD99_RS17110	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BMD99_RS17120	COG3547	Transposase (IS116 IS110 IS902 family)
BMD99_RS17135	COG1309	transcriptional regulator
BMD99_RS17170	COG2233	PERMEase
BMD99_RS17195	COG3729	General stress protein
BMD99_RS17225	COG4221	oxidoreductase activity
BMD99_RS17240	COG0531	amino acid
BMD99_RS17250	COG0174	glutamine synthetase
BMD99_RS17255	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
BMD99_RS17260	COG1917	Cupin 2, conserved barrel domain protein
BMD99_RS17260	COG1396	sequence-specific DNA binding
BMD99_RS17265	COG1012	belongs to the aldehyde dehydrogenase family
BMD99_RS17270	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BMD99_RS17275	COG0583	DNA-binding transcription factor activity
BMD99_RS17280	COG0473	3-isopropylmalate dehydrogenase activity
BMD99_RS17285	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BMD99_RS17285	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BMD99_RS17285	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BMD99_RS17290	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BMD99_RS17295	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BMD99_RS17300	COG1882	Formate acetyltransferase
BMD99_RS17305	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
BMD99_RS17310	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BMD99_RS17320	COG2207	Transcriptional regulator
BMD99_RS17325	COG3706	GGDEF domain
BMD99_RS17345	COG2200	EAL domain
BMD99_RS17355	COG0058	SHG alpha-glucan phosphorylase activity
BMD99_RS17370	COG0670	Belongs to the BI1 family
BMD99_RS17390	COG1881	PFAM PEBP family protein
BMD99_RS17405	COG1832	CoA-binding protein
BMD99_RS17415	COG0210	DNA helicase
BMD99_RS17420	COG3304	Inner membrane component domain
BMD99_RS17425	COG1289	transmembrane transporter activity
BMD99_RS17430	COG3070	regulator of competence-specific genes
BMD99_RS17450	COG1067	ATP-dependent peptidase activity
BMD99_RS17460	COG3130	regulation of translation
BMD99_RS17465	COG3009	Protein conserved in bacteria
BMD99_RS17470	COG3008	intermembrane lipid transfer
BMD99_RS17470	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
BMD99_RS17475	COG2995	paraquat-inducible protein a
BMD99_RS17480	COG0488	(ABC) transporter
BMD99_RS17490	COG0633	Ferredoxin
BMD99_RS17490	COG3217	Mosc domain protein beta barrel domain protein
BMD99_RS17505	COG0431	NADPH-dependent FMN reductase
BMD99_RS17510	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BMD99_RS17515	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BMD99_RS17520	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BMD99_RS17530	COG0308	aminopeptidase N
BMD99_RS17550	COG1448	Aminotransferase
BMD99_RS17565	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BMD99_RS17570	COG3108	Peptidase M15
BMD99_RS17575	COG2989	Protein conserved in bacteria
BMD99_RS17585	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
BMD99_RS17595	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
BMD99_RS17600	COG1434	Gram-negative-bacterium-type cell wall biogenesis
BMD99_RS17605	COG3173	Aminoglycoside phosphotransferase
BMD99_RS17620	COG3214	Protein conserved in bacteria
BMD99_RS17635	COG2333	competence protein COMEC
BMD99_RS17635	COG0658	competence protein
BMD99_RS17645	COG0539	negative regulation of cytoplasmic translation
BMD99_RS17665	COG2323	membrane
BMD99_RS17670	COG1944	ATP diphosphatase activity
BMD99_RS17675	COG2116	formate transmembrane transporter activity
BMD99_RS17680	COG1882	Formate acetyltransferase
BMD99_RS17685	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
BMD99_RS17690	COG0477	Major facilitator Superfamily
BMD99_RS17695	COG3302	dmso reductase anchor subunit
BMD99_RS17700	COG0437	4 iron, 4 sulfur cluster binding
BMD99_RS17705	COG0243	molybdopterin cofactor binding
BMD99_RS17715	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
BMD99_RS17725	COG1674	ftsk spoiiie
BMD99_RS17725	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
BMD99_RS17735	COG0492	ferredoxin-NADP+ reductase activity
BMD99_RS17740	COG4988	ABC transporter
BMD99_RS17745	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
BMD99_RS17760	COG0542	response to heat
BMD99_RS17775	COG1278	Cold shock
BMD99_RS17785	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BMD99_RS17790	COG3593	DNA synthesis involved in DNA repair
BMD99_RS17805	COG2431	L-lysine efflux transmembrane transporter activity
BMD99_RS17815	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BMD99_RS17830	COG0028	Belongs to the TPP enzyme family
BMD99_RS17835	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
BMD99_RS17840	COG0702	epimerase
BMD99_RS17845	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BMD99_RS17850	COG3023	N-Acetylmuramoyl-L-alanine amidase
BMD99_RS17855	COG5001	Diguanylate cyclase
BMD99_RS17855	COG4251	negative regulation of phosphorylation
BMD99_RS17855	COG3706	GGDEF domain
BMD99_RS17855	COG2203	Gaf domain
BMD99_RS17870	COG1126	abc transporter atp-binding protein
BMD99_RS17875	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BMD99_RS17880	COG4215	(ABC) transporter
BMD99_RS17885	COG4160	amino acid transport
BMD99_RS17890	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BMD99_RS17895	COG5002	protein histidine kinase activity
BMD99_RS17900	COG0745	RESPONSE REGULATOR receiver
BMD99_RS17915	COG1177	transmembrane transport
BMD99_RS17920	COG1176	ABC-type spermidine putrescine transport system, permease component I
BMD99_RS17925	COG3842	ATPase activity
BMD99_RS17930	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
BMD99_RS17945	COG0778	Nitroreductase
BMD99_RS17970	COG3226	Transcriptional regulator
BMD99_RS17975	COG0738	Major facilitator superfamily
BMD99_RS17980	COG0561	phosphatase activity
BMD99_RS17985	COG2814	Major facilitator Superfamily
BMD99_RS17995	COG0671	phosphoesterase, PA-phosphatase related
BMD99_RS18000	COG1349	DNA-binding transcription factor activity
BMD99_RS18005	COG1686	Belongs to the peptidase S11 family
BMD99_RS18010	COG0625	glutathione transferase activity
BMD99_RS18015	COG2133	pyrroloquinoline quinone binding
BMD99_RS18055	COG0747	negative chemotaxis
BMD99_RS18065	COG1446	asparaginase
BMD99_RS18070	COG0303	'Molybdopterin
BMD99_RS18075	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BMD99_RS18080	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
BMD99_RS18085	COG1882	Formate acetyltransferase
BMD99_RS18090	COG0561	phosphatase activity
BMD99_RS18100	COG0488	(ABC) transporter
BMD99_RS18110	COG1376	ErfK ybiS ycfS ynhG family protein
BMD99_RS18115	COG2188	Transcriptional regulator
BMD99_RS18120	COG2723	6-phospho-beta-galactosidase activity
BMD99_RS18125	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
BMD99_RS18140	COG2194	sulfuric ester hydrolase activity
BMD99_RS18145	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
BMD99_RS18160	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BMD99_RS18165	COG0765	amino acid transport
BMD99_RS18170	COG1126	abc transporter atp-binding protein
BMD99_RS18175	COG0668	transmembrane transport
BMD99_RS18185	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BMD99_RS18195	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
BMD99_RS18205	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
BMD99_RS18210	COG1199	ATP-dependent helicase activity
BMD99_RS18215	COG0513	Belongs to the DEAD box helicase family
BMD99_RS18220	COG3958	Transketolase
BMD99_RS18225	COG3959	Transketolase, thiamine diphosphate binding domain
BMD99_RS18230	COG1028	Short-chain dehydrogenase reductase Sdr
BMD99_RS18235	COG2271	Major facilitator Superfamily
BMD99_RS18240	COG0583	DNA-binding transcription factor activity
BMD99_RS18245	COG1309	transcriptional regulator
BMD99_RS18250	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BMD99_RS18255	COG1131	(ABC) transporter
BMD99_RS18260	COG0842	Transport permease protein
BMD99_RS18265	COG0842	Transport permease protein
BMD99_RS18275	COG3568	Endonuclease Exonuclease Phosphatase
BMD99_RS18280	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BMD99_RS18285	COG0392	lysyltransferase activity
BMD99_RS18305	COG0670	Belongs to the BI1 family
BMD99_RS18310	COG0314	molybdopterin synthase activity
BMD99_RS18315	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
BMD99_RS18325	COG0521	Mo-molybdopterin cofactor biosynthetic process
BMD99_RS18385	COG0410	ABC transporter
BMD99_RS18395	COG2226	methyltransferase
BMD99_RS18410	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BMD99_RS18415	COG1881	PFAM PEBP family protein
BMD99_RS18450	COG4677	pectinesterase activity
BMD99_RS18460	COG0589	response to stress
BMD99_RS18465	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BMD99_RS18495	COG0789	Transcriptional regulator
BMD99_RS18500	COG2200	EAL domain
BMD99_RS18525	COG0561	phosphatase activity
BMD99_RS18535	COG4149	molybdate abc transporter
BMD99_RS18540	COG0725	ABC transporter, periplasmic molybdate-binding protein
BMD99_RS18550	COG3585	molybdate ion transport
BMD99_RS18550	COG2005	Transcriptional regulator
BMD99_RS18555	COG1119	ATPase activity
BMD99_RS18565	COG1085	galactose-1-phosphate uridylyltransferase
BMD99_RS18575	COG2017	converts alpha-aldose to the beta-anomer
BMD99_RS18585	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
BMD99_RS18595	COG1230	cation diffusion facilitator family transporter
BMD99_RS18600	COG3201	nicotinamide mononucleotide transporter
BMD99_RS18605	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
BMD99_RS18655	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
BMD99_RS18660	COG2885	chlorophyll binding
BMD99_RS18670	COG3064	Membrane
BMD99_RS18675	COG0848	biopolymer transport protein
BMD99_RS18680	COG0811	peptide transport
BMD99_RS18685	COG0824	Thioesterase
BMD99_RS18690	COG3790	cyd operon protein YbgE
BMD99_RS18695	COG4890	Cyd operon protein YbgT
BMD99_RS18700	COG1294	oxidase, subunit
BMD99_RS18705	COG1271	oxidase subunit
BMD99_RS18710	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
BMD99_RS18725	COG0508	dehydrogenase complex catalyzes the overall conversion of
BMD99_RS18730	COG0567	Dehydrogenase, E1 component
BMD99_RS18735	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
BMD99_RS18740	COG1053	succinate dehydrogenase
BMD99_RS18745	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
BMD99_RS18750	COG2009	succinate dehydrogenase
BMD99_RS18775	COG1984	allophanate hydrolase subunit 2
BMD99_RS18780	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
BMD99_RS18795	COG0415	Belongs to the DNA photolyase family
BMD99_RS18825	COG2205	protein histidine kinase activity
BMD99_RS18830	COG0745	RESPONSE REGULATOR receiver
BMD99_RS18840	COG0033	Phosphoglucomutase
BMD99_RS18845	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
BMD99_RS18850	COG0596	Alpha beta hydrolase
BMD99_RS18865	COG0735	belongs to the Fur family
BMD99_RS18905	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
BMD99_RS18910	COG1940	carbohydrate kinase activity
BMD99_RS18910	COG1846	Transcriptional regulator
BMD99_RS18915	COG0647	UMP catabolic process
BMD99_RS18920	COG0367	asparagine synthase
BMD99_RS18955	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BMD99_RS18965	COG1702	phosphate starvation-inducible protein PhoH
BMD99_RS18990	COG0765	amino acid transport
BMD99_RS18995	COG0765	amino acid transport
BMD99_RS19000	COG1126	abc transporter atp-binding protein
BMD99_RS19015	COG2888	peptidyl-tyrosine sulfation
BMD99_RS19030	COG1466	dna polymerase III delta subunit
BMD99_RS19045	COG0799	negative regulation of ribosome biogenesis
BMD99_RS19055	COG0768	penicillin binding
BMD99_RS19060	COG0772	Belongs to the SEDS family
BMD99_RS19065	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
BMD99_RS19070	COG1686	Belongs to the peptidase S11 family
BMD99_RS19085	COG0583	DNA-binding transcription factor activity
BMD99_RS19100	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BMD99_RS19120	COG3069	C4-dicarboxylate transmembrane transporter activity
BMD99_RS19125	COG3719	Belongs to the RNase T2 family
BMD99_RS19130	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BMD99_RS19150	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
BMD99_RS19155	COG0583	DNA-binding transcription factor activity
BMD99_RS19160	COG3969	phosphoadenosine phosphosulfate
BMD99_RS19165	COG1475	DNA binding
BMD99_RS19170	COG0436	Aminotransferase
BMD99_RS19195	COG1129	ABC transporter
BMD99_RS19200	COG1172	Belongs to the binding-protein-dependent transport system permease family
BMD99_RS19205	COG1172	Belongs to the binding-protein-dependent transport system permease family
BMD99_RS19215	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BMD99_RS19230	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
BMD99_RS19240	COG0402	S-adenosylhomocysteine deaminase activity
BMD99_RS19250	COG0483	inositol monophosphate 1-phosphatase activity
BMD99_RS19255	COG2271	Major facilitator Superfamily
BMD99_RS19285	COG1172	Belongs to the binding-protein-dependent transport system permease family
BMD99_RS19290	COG1129	ABC transporter
BMD99_RS19295	COG0371	Dehydrogenase
BMD99_RS19300	COG1028	Short-chain dehydrogenase reductase Sdr
BMD99_RS19310	COG2879	small protein
BMD99_RS19315	COG1966	Carbon starvation protein
BMD99_RS19330	COG1028	Short-chain dehydrogenase reductase Sdr
BMD99_RS19335	COG1535	isochorismatase
BMD99_RS19335	COG3433	isochorismatase activity
BMD99_RS19340	COG1021	2,3-dihydroxybenzoate-AMP ligase
BMD99_RS19345	COG1169	isochorismate synthase
BMD99_RS19350	COG4592	Periplasmic binding protein
BMD99_RS19360	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BMD99_RS19365	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BMD99_RS19370	COG1120	ATPase activity
BMD99_RS19375	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
BMD99_RS19375	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BMD99_RS19380	COG3251	PFAM MbtH domain protein
BMD99_RS19385	COG2382	esterase
BMD99_RS19395	COG4771	TonB-dependent receptor
BMD99_RS19405	COG1879	ABC-type sugar transport system periplasmic component
BMD99_RS19415	COG1129	ABC transporter
BMD99_RS19420	COG1172	Belongs to the binding-protein-dependent transport system permease family
BMD99_RS19425	COG5464	transposase or invertase
BMD99_RS19430	COG2390	Transcriptional regulator
BMD99_RS19435	COG3959	Transketolase, thiamine diphosphate binding domain
BMD99_RS19440	COG3958	Transketolase
BMD99_RS19450	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
BMD99_RS19460	COG0583	DNA-binding transcription factor activity
BMD99_RS19465	COG0668	transmembrane transport
BMD99_RS19475	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BMD99_RS19500	COG0747	negative chemotaxis
BMD99_RS19505	COG0601	transmembrane transport
BMD99_RS19510	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BMD99_RS19515	COG0444	Belongs to the ABC transporter superfamily
BMD99_RS19520	COG4608	Belongs to the ABC transporter superfamily
BMD99_RS19535	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BMD99_RS19540	COG4221	oxidoreductase activity
BMD99_RS19550	COG4215	(ABC) transporter
BMD99_RS19555	COG0765	amino acid transport
BMD99_RS19560	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
BMD99_RS19575	COG0697	spore germination
BMD99_RS19585	COG3698	Phosphodiester glycosidase
BMD99_RS19630	COG2315	Protein conserved in bacteria
BMD99_RS19635	COG0778	Nitroreductase
BMD99_RS19665	COG0477	Major facilitator Superfamily
BMD99_RS19670	COG0668	transmembrane transport
BMD99_RS19675	COG1609	Transcriptional regulator
BMD99_RS19695	COG2211	Major facilitator Superfamily
BMD99_RS19700	COG1113	amino acid transport
BMD99_RS19715	COG1012	belongs to the aldehyde dehydrogenase family
BMD99_RS19720	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BMD99_RS19730	COG0531	amino acid
BMD99_RS19745	COG4680	protein conserved in bacteria
BMD99_RS19785	COG0667	Aldo Keto reductase
BMD99_RS19790	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BMD99_RS19795	COG1473	amidohydrolase
BMD99_RS19830	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BMD99_RS19835	COG1120	ATPase activity
BMD99_RS19840	COG1566	PFAM secretion protein HlyD family protein
BMD99_RS19885	COG4211	Belongs to the binding-protein-dependent transport system permease family
BMD99_RS19890	COG1129	ABC transporter
BMD99_RS19905	COG0673	inositol 2-dehydrogenase activity
BMD99_RS19940	COG3104	oligopeptide transport
BMD99_RS19945	COG1982	Orn Lys Arg decarboxylase major
BMD99_RS19950	COG0531	amino acid
BMD99_RS19955	COG3710	Transcriptional regulator
BMD99_RS19965	COG1560	Kdo2-lipid A biosynthetic process
BMD99_RS19980	COG3188	usher protein
BMD99_RS19985	COG3121	Chaperone
BMD99_RS19990	COG3539	Fimbrial protein
BMD99_RS20045	COG2501	S4 domain
BMD99_RS20050	COG3385	transposase activity
BMD99_RS20060	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
BMD99_RS20075	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
BMD99_RS20080	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
BMD99_RS20085	COG0549	Belongs to the carbamate kinase family
BMD99_RS20095	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
BMD99_RS20100	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
BMD99_RS20105	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
BMD99_RS20110	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BMD99_RS20115	COG3257	ureidoglycine aminohydrolase activity
BMD99_RS20120	COG1929	Belongs to the glycerate kinase type-1 family
BMD99_RS20125	COG2233	PERMEase
BMD99_RS20135	COG1953	Uracil, thiamine, allantoin
BMD99_RS20145	COG2084	Dehydrogenase
BMD99_RS20150	COG3622	Belongs to the hyi family
BMD99_RS20155	COG3960	tartronate-semialdehyde synthase activity
BMD99_RS20190	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
BMD99_RS20195	COG4181	ATPase activity
BMD99_RS20200	COG2755	lipolytic protein G-D-S-L family
BMD99_RS20205	COG0300	oxidoreductase activity
BMD99_RS20210	COG3118	belongs to the thioredoxin family
BMD99_RS20215	COG0390	transport system, permease component
BMD99_RS20220	COG4619	ABC transporter
BMD99_RS20225	COG0330	HflC and HflK could
BMD99_RS20230	COG1585	Membrane protein implicated in regulation of membrane protease activity
BMD99_RS20245	COG3735	TraB family
BMD99_RS20250	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
BMD99_RS20265	COG2223	nitrite transmembrane transporter activity
BMD99_RS20270	COG4651	solute:proton antiporter activity
BMD99_RS20270	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BMD99_RS20275	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BMD99_RS20315	COG2832	Protein of unknown function (DUF454)
BMD99_RS20320	COG3923	Primosomal replication protein n
BMD99_RS20335	COG1196	nuclear chromosome segregation
BMD99_RS20335	COG3264	Mechanosensitive ion channel
BMD99_RS20340	COG1309	transcriptional regulator
BMD99_RS20345	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BMD99_RS20350	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BMD99_RS20355	COG3335	DDE superfamily endonuclease
BMD99_RS20370	COG0110	maltose O-acetyltransferase activity
BMD99_RS20415	COG1874	Beta-galactosidase
BMD99_RS20420	COG3867	Arabinogalactan endo-beta-1,4-galactanase
BMD99_RS20425	COG3833	ABC-type maltose transport systems, permease component
BMD99_RS20430	COG1175	transmembrane transport
BMD99_RS20435	COG2182	Extracellular solute-binding protein
BMD99_RS20445	COG4943	cyclic-guanylate-specific phosphodiesterase activity
BMD99_RS20460	COG2364	Membrane
BMD99_RS20490	COG3695	enzyme binding
BMD99_RS20495	COG3126	Type III secretion system lipoprotein chaperone (YscW)
BMD99_RS20500	COG1946	Acyl-CoA thioesterase
BMD99_RS20505	COG3385	transposase activity
BMD99_RS20510	COG0004	ammonium transporteR
BMD99_RS20515	COG0347	Belongs to the P(II) protein family
BMD99_RS20520	COG1132	(ABC) transporter
BMD99_RS20525	COG1132	(ABC) transporter
BMD99_RS20530	COG1522	sequence-specific DNA binding
BMD99_RS20545	COG4533	DNA binding
BMD99_RS20555	COG0824	Thioesterase
BMD99_RS20560	COG1555	photosystem II stabilization
BMD99_RS20565	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BMD99_RS20570	COG0776	regulation of translation
BMD99_RS20575	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
BMD99_RS20605	COG0271	Belongs to the BolA IbaG family
BMD99_RS20610	COG3056	Lipoprotein
BMD99_RS20615	COG2223	nitrite transmembrane transporter activity
BMD99_RS20620	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
BMD99_RS20625	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BMD99_RS20630	COG1845	cytochrome c oxidase, subunit III
BMD99_RS20635	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
BMD99_RS20650	COG1414	Transcriptional regulator
BMD99_RS20655	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
BMD99_RS20660	COG1053	succinate dehydrogenase
BMD99_RS20670	COG1053	succinate dehydrogenase
BMD99_RS20685	COG0673	inositol 2-dehydrogenase activity
BMD99_RS20690	COG2814	Major facilitator Superfamily
BMD99_RS20700	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
BMD99_RS20725	COG0142	geranyltranstransferase activity
BMD99_RS20735	COG0667	Aldo Keto reductase
BMD99_RS20740	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
BMD99_RS20745	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
BMD99_RS20760	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BMD99_RS20760	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BMD99_RS20770	COG4238	major outer membrane lipoprotein
BMD99_RS20790	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BMD99_RS20795	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BMD99_RS20800	COG1862	Preprotein translocase
BMD99_RS20820	COG0450	alkyl hydroperoxide reductase
BMD99_RS20825	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BMD99_RS20840	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BMD99_RS20850	COG1228	amidohydrolase
BMD99_RS20860	COG1335	isochorismatase
BMD99_RS20865	COG0583	DNA-binding transcription factor activity
BMD99_RS20870	COG0366	Alpha amylase catalytic
BMD99_RS20895	COG3385	transposase activity
BMD99_RS20900	COG0420	3'-5' exonuclease activity
BMD99_RS20905	COG0419	ATPase involved in DNA repair
BMD99_RS20910	COG1940	carbohydrate kinase activity
BMD99_RS20925	COG4126	flavin adenine dinucleotide binding
BMD99_RS20935	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
BMD99_RS20940	COG3416	Protein conserved in bacteria
BMD99_RS20950	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BMD99_RS20960	COG1785	Belongs to the alkaline phosphatase family
BMD99_RS21000	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
BMD99_RS21005	COG1335	isochorismatase
BMD99_RS21010	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BMD99_RS21015	COG0113	porphobilinogen synthase activity
BMD99_RS21025	COG1943	Transposase
BMD99_RS21045	COG2175	clavaminate synthase activity
BMD99_RS21050	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BMD99_RS21055	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
BMD99_RS21060	COG4521	taurine ABC transporter
BMD99_RS21065	COG2040	homocysteine
BMD99_RS21070	COG0833	amino acid
BMD99_RS21080	COG4303	Ethanolamine ammonia lyase large subunit
BMD99_RS21085	COG4302	ethanolamine ammonia-lyase activity
BMD99_RS21125	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BMD99_RS21130	COG1126	abc transporter atp-binding protein
BMD99_RS21135	COG4597	amino acid ABC transporter
BMD99_RS21140	COG0765	amino acid transport
BMD99_RS21155	COG3188	usher protein
BMD99_RS21180	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
BMD99_RS21190	COG3639	organic phosphonate transmembrane transporter activity
BMD99_RS21230	COG0791	NLP P60 protein
BMD99_RS21265	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
BMD99_RS21280	COG0579	oxidoreductase
BMD99_RS21285	COG1012	belongs to the aldehyde dehydrogenase family
BMD99_RS21290	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
BMD99_RS21295	COG1113	amino acid transport
BMD99_RS21300	COG1802	Transcriptional regulator
BMD99_RS21320	COG2195	Cleaves the N-terminal amino acid of tripeptides
BMD99_RS21325	COG0454	-acetyltransferase
BMD99_RS21340	COG2991	Protein conserved in bacteria
BMD99_RS21355	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
BMD99_RS21360	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
BMD99_RS21380	COG3034	peptidoglycan biosynthetic process
BMD99_RS21385	COG0121	glutamine amidotransferase
BMD99_RS21395	COG1960	acyl-CoA dehydrogenase activity
BMD99_RS21400	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BMD99_RS21415	COG0583	DNA-binding transcription factor activity
BMD99_RS21435	COG2226	methyltransferase
BMD99_RS21445	COG0741	lytic transglycosylase activity
BMD99_RS21445	COG1388	LysM domain
BMD99_RS21450	COG2226	methyltransferase
BMD99_RS21460	COG2814	Major facilitator Superfamily
BMD99_RS21465	COG0583	DNA-binding transcription factor activity
BMD99_RS21470	COG0656	L-ascorbic acid biosynthetic process
BMD99_RS21505	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
BMD99_RS21515	COG2011	ABC-type metal ion transport system permease component
BMD99_RS21520	COG1464	Belongs to the NlpA lipoprotein family
BMD99_RS21530	COG1720	tRNA m6t6A37 methyltransferase activity
BMD99_RS21540	COG0791	NLP P60 protein
BMD99_RS21545	COG3015	lipoprotein NlpE involved in copper resistance
BMD99_RS21550	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
BMD99_RS21565	COG4568	rho-dependent transcription termination
BMD99_RS21575	COG0346	lactoylglutathione lyase activity
BMD99_RS21580	COG1982	Orn Lys Arg decarboxylase major
BMD99_RS21620	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
BMD99_RS21630	COG0750	zinc metalloprotease
BMD99_RS21635	COG0575	Belongs to the CDS family
BMD99_RS21650	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
BMD99_RS21675	COG0024	Methionine aminopeptidase
BMD99_RS21680	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
BMD99_RS21695	COG3835	regulator
BMD99_RS21700	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BMD99_RS21720	COG2860	membrane
BMD99_RS21740	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BMD99_RS21745	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BMD99_RS21750	COG1120	ATPase activity
BMD99_RS21755	COG4774	siderophore transport
BMD99_RS21760	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BMD99_RS21845	COG1643	Atp-dependent helicase
BMD99_RS21850	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
BMD99_RS21870	COG0617	tRNA 3'-terminal CCA addition
BMD99_RS21875	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
BMD99_RS21895	COG0726	polysaccharide deacetylase
BMD99_RS21900	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
BMD99_RS21905	COG0842	Transport permease protein
BMD99_RS21910	COG1131	(ABC) transporter
BMD99_RS21915	COG0288	reversible hydration of carbon dioxide
BMD99_RS21925	COG4993	Dehydrogenase
BMD99_RS21930	COG2132	Multicopper oxidase
BMD99_RS21975	COG3064	Membrane
BMD99_RS21990	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BMD99_RS21995	COG0508	dehydrogenase complex catalyzes the overall conversion of
BMD99_RS22000	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
BMD99_RS22005	COG2186	Transcriptional regulator
BMD99_RS22010	COG1113	amino acid transport
BMD99_RS22015	COG2211	Major facilitator Superfamily
BMD99_RS22020	COG3940	Belongs to the glycosyl hydrolase 43 family
BMD99_RS22025	COG3725	Membrane protein required for beta-lactamase induction
BMD99_RS22040	COG4969	Belongs to the N-Me-Phe pilin family
BMD99_RS22045	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
BMD99_RS22050	COG1459	type II secretion system
BMD99_RS22075	COG0494	nUDIX hydrolase
BMD99_RS22095	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
BMD99_RS22100	COG0849	cell division
BMD99_RS22125	COG0772	Belongs to the SEDS family
BMD99_RS22140	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
BMD99_RS22150	COG0768	penicillin binding
BMD99_RS22170	COG1609	Transcriptional regulator
BMD99_RS22180	COG0028	Belongs to the TPP enzyme family
BMD99_RS22220	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
BMD99_RS22225	COG0738	Major facilitator superfamily
BMD99_RS22235	COG0583	DNA-binding transcription factor activity
BMD99_RS22240	COG2271	Major facilitator Superfamily
BMD99_RS22245	COG2814	Major facilitator Superfamily
BMD99_RS22270	COG1178	ABC-type Fe3 transport system permease component
BMD99_RS22280	COG0586	Pfam SNARE associated Golgi protein
BMD99_RS22300	COG0235	Class ii aldolase
BMD99_RS22305	COG0417	DNA replication proofreading
BMD99_RS22315	COG0564	pseudouridine synthase activity
BMD99_RS22330	COG3493	citrate carrier protein
BMD99_RS22345	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
BMD99_RS22350	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
BMD99_RS22360	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
BMD99_RS22385	COG3547	Transposase (IS116 IS110 IS902 family)
BMD99_RS22405	COG2271	Major facilitator Superfamily
BMD99_RS22410	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BMD99_RS22415	COG1609	Transcriptional regulator
BMD99_RS22420	COG1028	Short-chain dehydrogenase reductase Sdr
BMD99_RS22425	COG3265	gluconokinase activity
BMD99_RS22430	COG2731	YhcH YjgK YiaL family protein
BMD99_RS22445	COG0505	Belongs to the CarA family
BMD99_RS22535	COG1047	Peptidyl-prolyl cis-trans
BMD99_RS22550	COG0196	riboflavin kinase activity
BMD99_RS22590	COG4735	regulation of single-species biofilm formation
BMD99_RS22595	COG1584	GPR1 FUN34 yaaH family protein
BMD99_RS22600	COG0477	Major facilitator Superfamily
BMD99_RS22605	COG0521	Mo-molybdopterin cofactor biosynthetic process
BMD99_RS22610	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
BMD99_RS22615	COG1115	amino acid carrier protein
BMD99_RS22630	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
BMD99_RS22640	COG0527	aspartate kinase activity
BMD99_RS22640	COG0460	homoserine dehydrogenase
BMD99_RS22650	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
BMD99_RS22660	COG0745	RESPONSE REGULATOR receiver
BMD99_RS22665	COG4452	Inner membrane protein CreD
BMD99_RS22670	COG2205	protein histidine kinase activity
BMD99_RS22675	COG0745	RESPONSE REGULATOR receiver
BMD99_RS22680	COG3045	CreA protein
BMD99_RS22685	COG2207	Transcriptional regulator
BMD99_RS22685	COG3708	Transcriptional regulator
BMD99_RS22705	COG0741	lytic transglycosylase activity
BMD99_RS22710	COG0488	(ABC) transporter
BMD99_RS22720	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
BMD99_RS22725	COG0560	Phosphoserine phosphatase
BMD99_RS22735	COG3726	membrane protein affecting hemolysin expression
BMD99_RS22765	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BMD99_RS22770	COG0084	hydrolase, TatD family'
BMD99_RS22775	COG4667	esterase of the alpha-beta hydrolase superfamily
BMD99_RS22785	COG2823	Periplasmic or secreted lipoprotein
BMD99_RS22795	COG1011	Hydrolase
BMD99_RS22800	COG0456	acetyltransferase
BMD99_RS22805	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
BMD99_RS22825	COG3706	GGDEF domain
BMD99_RS22830	COG4114	ferric iron reductase
BMD99_RS22835	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BMD99_RS22835	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BMD99_RS22840	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
BMD99_RS22845	COG2197	response regulator
BMD99_RS22850	COG2197	response regulator
BMD99_RS22865	COG2966	Psort location CytoplasmicMembrane, score
BMD99_RS22880	COG1484	DNA-dependent DNA replication
BMD99_RS22895	COG5464	transposase or invertase
BMD99_RS22905	COG1063	alcohol dehydrogenase
BMD99_RS22910	COG1802	Transcriptional regulator
BMD99_RS22915	COG2271	Major facilitator Superfamily
BMD99_RS22920	COG0456	acetyltransferase
BMD99_RS22920	COG1214	PFAM Peptidase M22, glycoprotease
BMD99_RS22930	COG1737	Transcriptional regulator
BMD99_RS22935	COG0800	Aldolase
BMD99_RS22940	COG3734	2-keto-3-deoxy-galactonokinase
BMD99_RS22955	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
BMD99_RS22990	COG0531	amino acid
BMD99_RS22995	COG1012	belongs to the aldehyde dehydrogenase family
BMD99_RS23000	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BMD99_RS23015	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
BMD99_RS23015	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BMD99_RS23030	COG1846	Transcriptional regulator
BMD99_RS23035	COG0179	Fumarylacetoacetate (FAA) hydrolase
BMD99_RS23045	COG1012	belongs to the aldehyde dehydrogenase family
BMD99_RS23050	COG3384	dioxygenase
BMD99_RS23060	COG3971	2-oxopent-4-enoate hydratase activity
BMD99_RS23080	COG2368	4-hydroxyphenylacetate
BMD99_RS23085	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BMD99_RS23090	COG1966	Carbon starvation protein
BMD99_RS23095	COG2879	small protein
BMD99_RS23100	COG0523	cobalamin synthesis protein
BMD99_RS23110	COG1012	belongs to the aldehyde dehydrogenase family
BMD99_RS23115	COG5464	transposase or invertase
BMD99_RS23120	COG2207	Transcriptional regulator
BMD99_RS23120	COG1917	Cupin 2, conserved barrel domain protein
BMD99_RS23130	COG2733	membrane
BMD99_RS23145	COG1775	2-hydroxyglutaryl-CoA dehydratase, D-component
BMD99_RS23150	COG1924	4 iron, 4 sulfur cluster binding
BMD99_RS23165	COG1566	PFAM secretion protein HlyD family protein
BMD99_RS23175	COG5457	Domain of unknown function (DUF1127)
BMD99_RS23180	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BMD99_RS23200	COG0583	DNA-binding transcription factor activity
BMD99_RS23205	COG2249	NAD(P)H dehydrogenase (quinone) activity
BMD99_RS23215	COG1172	Belongs to the binding-protein-dependent transport system permease family
BMD99_RS23220	COG1129	ABC transporter
BMD99_RS23235	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BMD99_RS23240	COG1129	ABC transporter
BMD99_RS23240	COG0842	Transport permease protein
BMD99_RS23245	COG0842	Transport permease protein
BMD99_RS23280	COG2850	peptidyl-arginine hydroxylation
BMD99_RS23295	COG5002	protein histidine kinase activity
BMD99_RS23300	COG0745	RESPONSE REGULATOR receiver
BMD99_RS23310	COG1538	Outer membrane efflux protein
BMD99_RS23315	COG5569	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BMD99_RS23320	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BMD99_RS23325	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BMD99_RS23335	COG3040	lipid binding
BMD99_RS23340	COG0789	Transcriptional regulator
BMD99_RS23345	COG3631	Ketosteroid isomerase-related protein
BMD99_RS23350	COG0300	oxidoreductase activity
BMD99_RS23365	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
BMD99_RS23385	COG3272	Protein of unknown function (DUF1722)
BMD99_RS23395	COG4580	involved in the transport of maltose and maltodextrins
BMD99_RS23400	COG2115	Belongs to the xylose isomerase family
BMD99_RS23405	COG2211	Major facilitator Superfamily
BMD99_RS23410	COG3507	Belongs to the glycosyl hydrolase 43 family
BMD99_RS23495	COG0659	secondary active sulfate transmembrane transporter activity
BMD99_RS23500	COG1064	alcohol dehydrogenase
BMD99_RS23505	COG1175	transmembrane transport
BMD99_RS23510	COG0395	ABC-type sugar transport system, permease component
BMD99_RS23515	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
BMD99_RS23520	COG3842	ATPase activity
BMD99_RS23525	COG1653	transport
BMD99_RS23535	COG1082	Xylose isomerase domain protein TIM barrel
BMD99_RS23545	COG3962	Belongs to the TPP enzyme family
BMD99_RS23550	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BMD99_RS23555	COG0837	glucose binding
BMD99_RS23555	COG1737	Transcriptional regulator
BMD99_RS23570	COG3718	enzyme involved in inositol metabolism
BMD99_RS23585	COG0433	COG0433 Predicted ATPase
BMD99_RS23590	COG0795	lipopolysaccharide-transporting ATPase activity
BMD99_RS23595	COG0795	lipopolysaccharide-transporting ATPase activity
BMD99_RS23610	COG2927	DNA polymerase III (CHI subunit)
BMD99_RS23615	COG0525	valine-tRNA ligase activity
BMD99_RS23640	COG3547	Transposase (IS116 IS110 IS902 family)
BMD99_RS23660	COG2731	YhcH YjgK YiaL family protein
BMD99_RS23680	COG0251	oxidation-reduction process
BMD99_RS23685	COG3525	Glycosyl hydrolase, family 20, catalytic domain
BMD99_RS23705	COG1263	PTS System
BMD99_RS23705	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BMD99_RS23710	COG0366	Alpha amylase catalytic
BMD99_RS23720	COG0602	queuosine metabolic process
BMD99_RS23725	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BMD99_RS23725	COG3711	transcriptional antiterminator
BMD99_RS23730	COG2706	6-phosphogluconolactonase activity
BMD99_RS23745	COG3964	amidohydrolase
BMD99_RS23780	COG0312	modulator of DNA gyrase
BMD99_RS23800	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
BMD99_RS23810	COG1172	Belongs to the binding-protein-dependent transport system permease family
BMD99_RS23815	COG1172	Belongs to the binding-protein-dependent transport system permease family
BMD99_RS23820	COG1129	ABC transporter
BMD99_RS23825	COG1879	ABC-type sugar transport system periplasmic component
BMD99_RS23845	COG2105	PFAM AIG2 family protein
BMD99_RS23850	COG2911	Protein conserved in bacteria
BMD99_RS23855	COG0729	surface antigen
BMD99_RS23890	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BMD99_RS23895	COG1609	Transcriptional regulator
BMD99_RS23900	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
BMD99_RS23905	COG1253	flavin adenine dinucleotide binding
BMD99_RS23930	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
BMD99_RS23950	COG1733	regulation of RNA biosynthetic process
BMD99_RS23955	COG0702	epimerase
BMD99_RS23965	COG0697	spore germination
BMD99_RS23975	COG1113	amino acid transport
BMD99_RS23980	COG0545	Peptidyl-prolyl cis-trans isomerase
BMD99_RS23985	COG3061	Opacity-associated protein A
BMD99_RS23995	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
BMD99_RS24000	COG2965	DNA replication, synthesis of RNA primer
BMD99_RS24060	COG1073	alpha beta
BMD99_RS24065	COG3650	response to hydrogen peroxide
BMD99_RS24075	COG1960	acyl-CoA dehydrogenase activity
BMD99_RS24080	COG0754	glutathionylspermidine amidase activity
BMD99_RS24085	COG5463	Belongs to the UPF0441 family
BMD99_RS24090	COG3766	membrane
BMD99_RS24100	COG1842	Phage shock protein A
BMD99_RS24105	COG3789	protein conserved in bacteria
BMD99_RS24110	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BMD99_RS24115	COG0557	exoribonuclease II activity
BMD99_RS24130	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
BMD99_RS24140	COG0330	HflC and HflK could
BMD99_RS24145	COG0330	HflC and HflK could
BMD99_RS24150	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BMD99_RS24170	COG0860	N-Acetylmuramoyl-L-alanine amidase
BMD99_RS24175	COG0802	atpase or kinase
BMD99_RS24180	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
BMD99_RS24180	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
BMD99_RS24185	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
BMD99_RS24210	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BMD99_RS24235	COG1511	domain protein
BMD99_RS24235	COG3264	Mechanosensitive ion channel
BMD99_RS24250	COG1053	succinate dehydrogenase
BMD99_RS24255	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
BMD99_RS24275	COG2076	Multidrug Resistance protein
BMD99_RS24280	COG5510	response to toxic substance
BMD99_RS24295	COG1509	lysine 2,3-aminomutase activity
BMD99_RS24300	COG0745	RESPONSE REGULATOR receiver
BMD99_RS24340	COG3335	DDE superfamily endonuclease
BMD99_RS24395	COG0531	amino acid
BMD99_RS24400	COG3030	protein affecting phage T7 exclusion by the F plasmid
BMD99_RS24410	COG1027	Aspartate ammonia-lyase
BMD99_RS24415	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
BMD99_RS24430	COG1309	transcriptional regulator
BMD99_RS24455	COG0457	Tetratricopeptide repeat
BMD99_RS24460	COG0726	polysaccharide deacetylase
BMD99_RS24460	COG1649	PFAM Uncharacterised BCR, COG1649
BMD99_RS24465	COG1215	transferase activity, transferring glycosyl groups
BMD99_RS24485	COG0861	Integral membrane protein TerC family
BMD99_RS24520	COG1486	melibiose metabolic process
BMD99_RS24530	COG2169	Transcriptional regulator
BMD99_RS24545	COG2824	Alkylphosphonate utilization operon protein PhnA
BMD99_RS24550	COG2764	glyoxalase bleomycin resistance protein dioxygenase
BMD99_RS24555	COG2188	Transcriptional regulator
BMD99_RS24560	COG3624	Phosphonate C-P lyase system protein PhnG
BMD99_RS24565	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
BMD99_RS24570	COG3626	phosphonate metabolism
BMD99_RS24575	COG3627	carbon phosphorus lyase activity
BMD99_RS24580	COG4107	phosphonate C-P lyase system protein PhnK
BMD99_RS24585	COG4778	phosphonate C-P lyase system protein PhnL
BMD99_RS24590	COG3454	Phosphonate metabolism
BMD99_RS24600	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
BMD99_RS24610	COG4191	Histidine kinase
BMD99_RS24610	COG0784	Response regulator, receiver
BMD99_RS24615	COG1129	ABC transporter
BMD99_RS24620	COG1172	Belongs to the binding-protein-dependent transport system permease family
BMD99_RS24640	COG3385	transposase activity
BMD99_RS24660	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
BMD99_RS24665	COG1301	dicarboxylic acid transport
BMD99_RS24675	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BMD99_RS24685	COG3162	membrane
BMD99_RS24715	COG3539	Fimbrial protein
BMD99_RS24720	COG1346	cytolysis
BMD99_RS24725	COG1380	Effector of murein hydrolase LrgA
BMD99_RS24730	COG0583	DNA-binding transcription factor activity
BMD99_RS24735	COG0025	NhaP-type Na H and K H
BMD99_RS24740	COG2252	PERMEase
BMD99_RS24745	COG0625	glutathione transferase activity
BMD99_RS24750	COG0789	Transcriptional regulator
BMD99_RS24760	COG4943	cyclic-guanylate-specific phosphodiesterase activity
BMD99_RS24790	COG1234	tRNA 3'-trailer cleavage
BMD99_RS24795	COG1609	Transcriptional regulator
BMD99_RS24800	COG0483	inositol monophosphate 1-phosphatase activity
BMD99_RS24810	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BMD99_RS24830	COG4771	TonB-dependent receptor
BMD99_RS24835	COG0741	lytic transglycosylase activity
BMD99_RS24855	COG2315	Protein conserved in bacteria
BMD99_RS24860	COG0432	Pfam Uncharacterised protein family UPF0047
BMD99_RS24875	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BMD99_RS24880	COG0305	Participates in initiation and elongation during chromosome replication
BMD99_RS24895	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BMD99_RS24905	COG0735	belongs to the Fur family
BMD99_RS24910	COG3237	CsbD-like
BMD99_RS24915	COG0534	Mate efflux family protein
BMD99_RS24925	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
BMD99_RS24990	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
BMD99_RS25005	COG0527	aspartate kinase activity
BMD99_RS25070	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
BMD99_RS25100	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
BMD99_RS25110	COG0456	acetyltransferase
BMD99_RS25145	COG0151	Belongs to the GarS family
BMD99_RS25155	COG4191	Histidine kinase
BMD99_RS25195	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
BMD99_RS25210	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BMD99_RS25215	COG2104	thiamine diphosphate biosynthetic process
BMD99_RS25230	COG3706	GGDEF domain
BMD99_RS25240	COG1447	Phosphotransferase system cellobiose-specific component IIA
BMD99_RS25245	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
BMD99_RS25280	COG0250	Participates in transcription elongation, termination and antitermination
BMD99_RS25330	COG0812	UDP-N-acetylmuramate dehydrogenase activity
BMD99_RS25360	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
BMD99_RS25370	COG1739	Uncharacterized protein family UPF0029
BMD99_RS25415	COG0805	protein transport
BMD99_RS25435	COG3165	ubiquinone biosynthetic process from chorismate
BMD99_RS25455	COG0412	Dienelactone hydrolase
BMD99_RS25465	COG0583	DNA-binding transcription factor activity
BMD99_RS25470	COG0697	spore germination
BMD99_RS25475	COG0561	phosphatase activity
BMD99_RS25480	COG2267	carboxylic ester hydrolase activity
BMD99_RS25485	COG1280	lysine exporter protein (LysE YggA)
BMD99_RS25495	COG1280	lysine exporter protein (LysE YggA)
BMD99_RS25525	COG0210	DNA helicase
BMD99_RS25530	COG1011	Hydrolase
BMD99_RS25560	COG3072	Adenylate cyclase
BMD99_RS25575	COG2959	enzyme of heme biosynthesis
BMD99_RS25580	COG3071	HemY protein
BMD99_RS25625	COG2244	polysaccharide biosynthetic process
BMD99_RS25630	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
BMD99_RS25635	COG0456	acetyltransferase
BMD99_RS25640	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
BMD99_RS25645	COG1088	dTDP-glucose 4,6-dehydratase activity
BMD99_RS25650	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
BMD99_RS25655	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
BMD99_RS25665	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BMD99_RS25670	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
BMD99_RS25680	COG3118	belongs to the thioredoxin family
BMD99_RS25710	COG1811	Na channel or pump
BMD99_RS25720	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BMD99_RS25725	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BMD99_RS25735	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BMD99_RS25740	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
BMD99_RS25740	COG0473	3-isopropylmalate dehydrogenase activity
BMD99_RS25745	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BMD99_RS25765	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
BMD99_RS25780	COG3978	acetolactate synthase activity
BMD99_RS25800	COG3085	chromosome segregation
BMD99_RS25875	COG0583	DNA-binding transcription factor activity
BMD99_RS25900	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
BMD99_RS25915	COG3443	Belongs to the bacterial solute-binding protein 9 family
BMD99_RS25920	COG2207	Transcriptional regulator
BMD99_RS25930	COG0371	Dehydrogenase
BMD99_RS25935	COG0697	spore germination
BMD99_RS25945	COG0583	DNA-binding transcription factor activity
BMD99_RS25955	COG0527	aspartate kinase activity
BMD99_RS25955	COG0460	homoserine dehydrogenase
BMD99_RS25960	COG0626	cystathionine gamma-synthase activity
BMD99_RS25975	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
BMD99_RS25980	COG1609	Transcriptional regulator
BMD99_RS25985	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
BMD99_RS26000	COG1575	Belongs to the MenA family. Type 1 subfamily
BMD99_RS26020	COG3678	ATP-independent chaperone mediated protein folding
BMD99_RS26025	COG0745	RESPONSE REGULATOR receiver
BMD99_RS26030	COG2205	protein histidine kinase activity
BMD99_RS26035	COG2258	MOSC domain
BMD99_RS26040	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BMD99_RS26085	COG1129	ABC transporter
BMD99_RS26090	COG1172	Belongs to the binding-protein-dependent transport system permease family
BMD99_RS26095	COG1172	Belongs to the binding-protein-dependent transport system permease family
BMD99_RS26100	COG1454	alcohol dehydrogenase
BMD99_RS26110	COG0110	maltose O-acetyltransferase activity
BMD99_RS26115	COG2211	Major facilitator Superfamily
BMD99_RS26175	COG0205	6-phosphofructokinase activity
BMD99_RS26190	COG0243	molybdopterin cofactor binding
BMD99_RS26190	COG3383	formate dehydrogenase (NAD+) activity
BMD99_RS26195	COG0243	molybdopterin cofactor binding
BMD99_RS26195	COG3383	formate dehydrogenase (NAD+) activity
BMD99_RS26200	COG0437	4 iron, 4 sulfur cluster binding
BMD99_RS26205	COG2864	formate dehydrogenase
BMD99_RS26220	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
BMD99_RS26230	COG0456	acetyltransferase
BMD99_RS26245	COG1011	Hydrolase
BMD99_RS26250	COG2271	Major facilitator Superfamily
BMD99_RS26255	COG1082	Xylose isomerase domain protein TIM barrel
BMD99_RS26260	COG2188	Transcriptional regulator
BMD99_RS26275	COG3852	Histidine kinase
BMD99_RS26285	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BMD99_RS26320	COG0204	Acyl-transferase
BMD99_RS26325	COG3385	transposase activity
BMD99_RS26335	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BMD99_RS26340	COG3084	Protein conserved in bacteria
BMD99_RS26350	COG1763	Mo-molybdopterin cofactor biosynthetic process
BMD99_RS26375	COG2186	Transcriptional regulator
BMD99_RS26380	COG0477	Major facilitator Superfamily
BMD99_RS26385	COG1609	Transcriptional regulator
BMD99_RS26390	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BMD99_RS26400	COG1172	Belongs to the binding-protein-dependent transport system permease family
BMD99_RS26405	COG1129	ABC transporter
BMD99_RS26435	COG1522	sequence-specific DNA binding
BMD99_RS26440	COG0716	FMN binding
BMD99_RS26455	COG3312	ion transport
BMD99_RS26505	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
BMD99_RS26510	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
BMD99_RS26515	COG0573	inorganic phosphate transmembrane transporter activity
BMD99_RS26520	COG0581	inorganic phosphate transmembrane transporter activity
BMD99_RS26525	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
BMD99_RS26530	COG0704	Plays a role in the regulation of phosphate uptake
BMD99_RS26545	COG2382	esterase
BMD99_RS26550	COG0363	glucosamine-6-phosphate deaminase activity
BMD99_RS26555	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BMD99_RS26565	COG2252	PERMEase
BMD99_RS26570	COG0431	NADPH-dependent FMN reductase
BMD99_RS26575	COG2091	lysine biosynthetic process via aminoadipic acid
BMD99_RS26605	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
BMD99_RS26645	COG3547	Transposase (IS116 IS110 IS902 family)
BMD99_RS26660	COG2423	ornithine cyclodeaminase activity
BMD99_RS26665	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
BMD99_RS26670	COG1126	abc transporter atp-binding protein
BMD99_RS26675	COG1126	abc transporter atp-binding protein
BMD99_RS26680	COG0765	amino acid transport
BMD99_RS26685	COG0765	amino acid transport
BMD99_RS26690	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BMD99_RS26695	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BMD99_RS26700	COG0006	proline dipeptidase activity
BMD99_RS26705	COG3608	succinylglutamate desuccinylase aspartoacylase
BMD99_RS26730	COG0110	maltose O-acetyltransferase activity
BMD99_RS26735	COG2223	nitrite transmembrane transporter activity
BMD99_RS26745	COG1609	Transcriptional regulator
BMD99_RS26770	COG3436	PFAM IS66 Orf2 family protein
BMD99_RS26775	COG1120	ATPase activity
BMD99_RS26780	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BMD99_RS26785	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BMD99_RS26790	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
BMD99_RS26795	COG4772	TonB-dependent receptor
BMD99_RS26800	COG3712	iron ion homeostasis
BMD99_RS26805	COG1595	DNA-templated transcription, initiation
BMD99_RS26840	COG0501	Belongs to the peptidase M48B family
BMD99_RS26860	COG0542	response to heat
BMD99_RS26865	COG0071	Belongs to the small heat shock protein (HSP20) family
BMD99_RS26935	COG4372	Transposase
BMD99_RS26940	COG3436	PFAM IS66 Orf2 family protein
BMD99_RS26965	COG5569	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BMD99_RS26995	COG0739	heme binding
BMD99_RS27005	COG2132	Multicopper oxidase
BMD99_RS27010	COG3667	copper resistance
BMD99_RS27015	COG2372	response to copper ion
BMD99_RS27020	COG1276	copper resistance
BMD99_RS27025	COG0745	RESPONSE REGULATOR receiver
BMD99_RS27030	COG2205	protein histidine kinase activity
BMD99_RS27040	COG3039	Transposase
BMD99_RS27070	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
BMD99_RS27095	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BMD99_RS27135	COG2801	Transposase and inactivated derivatives
BMD99_RS27145	COG2801	Transposase and inactivated derivatives
BMD99_RS27240	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
BMD99_RS27270	COG2188	Transcriptional regulator
BMD99_RS27275	COG0402	S-adenosylhomocysteine deaminase activity
BMD99_RS27290	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
BMD99_RS27295	COG0318	PFAM AMP-dependent synthetase and ligase
BMD99_RS27310	COG3677	Transposase
BMD99_RS27315	COG3677	Transposase
BMD99_RS27315	COG1662	PFAM IS1 transposase
BMD99_RS27360	COG4598	ABC transporter
BMD99_RS27365	COG0765	amino acid transport
BMD99_RS27370	COG0765	amino acid transport
BMD99_RS27380	COG0583	DNA-binding transcription factor activity
BMD99_RS27420	COG0789	Transcriptional regulator
BMD99_RS27470	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
BMD99_RS27500	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BMD99_RS27575	COG0697	spore germination
BMD99_RS27750	COG3547	Transposase (IS116 IS110 IS902 family)
BMD99_RS27840	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
BMD99_RS27935	COG1702	phosphate starvation-inducible protein PhoH
BMD99_RS27960	COG0338	D12 class N6 adenine-specific DNA methyltransferase
BMD99_RS28325	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
BMD99_RS28350	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BMD99_RS28365	COG0419	ATPase involved in DNA repair
BMD99_RS28405	COG3344	reverse transcriptase
BMD99_RS28415	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BMD99_RS28545	COG1528	Iron-storage protein
BMD99_RS28565	COG0463	Glycosyl transferase, family 2
BMD99_RS28680	COG3344	reverse transcriptase
BMD99_RS28810	COG5499	transcription regulator containing HTH domain
BMD99_RS28950	COG1342	Belongs to the UPF0251 family
BMD99_RS28965	COG0463	Glycosyl transferase, family 2
BMD99_RS28980	COG4644	lycopene metabolic process
BMD99_RS29015	COG4644	lycopene metabolic process
BMD99_RS29030	COG1216	Glycosyl transferase, family 2
BMD99_RS29030	COG1442	glycosyl transferase family 8
BMD99_RS29055	COG2244	polysaccharide biosynthetic process
BMD99_RS29135	COG2314	TM2 domain