locus-tag	class	description
KR75_RS00035	COG1253	flavin adenine dinucleotide binding
KR75_RS00040	COG2982	Protein involved in outer membrane biogenesis
KR75_RS00055	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
KR75_RS00060	COG0443	Heat shock 70 kDa protein
KR75_RS00065	COG5002	protein histidine kinase activity
KR75_RS00080	COG1301	dicarboxylic acid transport
KR75_RS00105	COG2205	protein histidine kinase activity
KR75_RS00110	COG0745	RESPONSE REGULATOR receiver
KR75_RS00115	COG0826	peptidase U32
KR75_RS00125	COG4608	Belongs to the ABC transporter superfamily
KR75_RS00130	COG0444	Belongs to the ABC transporter superfamily
KR75_RS00135	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KR75_RS00140	COG0601	transmembrane transport
KR75_RS00145	COG0747	negative chemotaxis
KR75_RS00150	COG4948	Mandelate Racemase Muconate Lactonizing
KR75_RS00155	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
KR75_RS00165	COG1070	Carbohydrate kinase
KR75_RS00180	COG1830	Aldolase
KR75_RS00185	COG0351	phosphomethylpyrimidine kinase
KR75_RS00200	COG0583	DNA-binding transcription factor activity
KR75_RS00210	COG2252	PERMEase
KR75_RS00215	COG0583	DNA-binding transcription factor activity
KR75_RS00220	COG5455	response to cobalt ion
KR75_RS00240	COG4807	Protein conserved in bacteria
KR75_RS00250	COG3275	phosphorelay sensor kinase activity
KR75_RS00255	COG1174	glycine betaine transport
KR75_RS00260	COG1125	glycine betaine transport
KR75_RS00265	COG1174	glycine betaine transport
KR75_RS00270	COG1732	Glycine betaine
KR75_RS00275	COG1472	Belongs to the glycosyl hydrolase 3 family
KR75_RS00280	COG0277	FAD linked oxidase domain protein
KR75_RS00290	COG1686	Belongs to the peptidase S11 family
KR75_RS00300	COG0586	Pfam SNARE associated Golgi protein
KR75_RS00305	COG1538	Outer membrane efflux protein
KR75_RS00315	COG2723	6-phospho-beta-galactosidase activity
KR75_RS00330	COG3659	wide pore channel activity
KR75_RS00335	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KR75_RS00345	COG1346	cytolysis
KR75_RS00355	COG2949	membrane
KR75_RS00380	COG1129	ABC transporter
KR75_RS00395	COG2311	Membrane
KR75_RS00410	COG4771	TonB-dependent receptor
KR75_RS00415	COG0833	amino acid
KR75_RS00420	COG0583	DNA-binding transcription factor activity
KR75_RS00425	COG2855	membrane
KR75_RS00435	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KR75_RS00435	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KR75_RS00435	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
KR75_RS00440	COG1105	Belongs to the carbohydrate kinase PfkB family
KR75_RS00445	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
KR75_RS00445	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
KR75_RS00450	COG2814	Major facilitator Superfamily
KR75_RS00455	COG1566	PFAM secretion protein HlyD family protein
KR75_RS00480	COG1312	Catalyzes the dehydration of D-mannonate
KR75_RS00485	COG0246	Mannitol dehydrogenase
KR75_RS00490	COG0523	cobalamin synthesis protein
KR75_RS00495	COG0671	phosphoesterase, PA-phosphatase related
KR75_RS00500	COG0791	NLP P60 protein
KR75_RS00505	COG2200	EAL domain
KR75_RS00510	COG4166	transmembrane transport
KR75_RS00515	COG4174	ABC transporter (Permease)
KR75_RS00520	COG4239	(ABC) transporter, permease
KR75_RS00525	COG4172	Belongs to the ABC transporter superfamily
KR75_RS00535	COG2814	Major facilitator Superfamily
KR75_RS00540	COG1187	pseudouridine synthase activity
KR75_RS00545	COG1061	Type III restriction enzyme res subunit
KR75_RS00565	COG0494	nUDIX hydrolase
KR75_RS00570	COG1349	DNA-binding transcription factor activity
KR75_RS00595	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KR75_RS00610	COG0765	amino acid transport
KR75_RS00615	COG0765	amino acid transport
KR75_RS00620	COG1126	abc transporter atp-binding protein
KR75_RS00635	COG0628	permease
KR75_RS00650	COG0659	secondary active sulfate transmembrane transporter activity
KR75_RS00655	COG2239	Acts as a magnesium transporter
KR75_RS00660	COG4615	Cyclic peptide transporter
KR75_RS00665	COG3145	DNA-N1-methyladenine dioxygenase activity
KR75_RS00670	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
KR75_RS00670	COG2169	Transcriptional regulator
KR75_RS00685	COG2198	Histidine kinase
KR75_RS00685	COG0642	Histidine kinase
KR75_RS00720	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
KR75_RS00725	COG0584	glycerophosphoryl diester phosphodiesterase
KR75_RS00730	COG2271	Major facilitator Superfamily
KR75_RS00735	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
KR75_RS00745	COG0247	lactate metabolic process
KR75_RS00755	COG2271	Major facilitator Superfamily
KR75_RS00765	COG1414	Transcriptional regulator
KR75_RS00780	COG5464	transposase or invertase
KR75_RS00790	COG0318	PFAM AMP-dependent synthetase and ligase
KR75_RS00815	COG1169	isochorismate synthase
KR75_RS00820	COG2153	protein acetylation
KR75_RS00835	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
KR75_RS00840	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
KR75_RS00850	COG0839	Belongs to the complex I subunit 6 family
KR75_RS00895	COG0583	DNA-binding transcription factor activity
KR75_RS00900	COG0436	Aminotransferase
KR75_RS00910	COG0490	domain, Protein
KR75_RS00910	COG0471	metal ion transport
KR75_RS00915	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
KR75_RS00940	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
KR75_RS00945	COG0622	Phosphoesterase
KR75_RS00950	COG0625	glutathione transferase activity
KR75_RS00955	COG0625	glutathione transferase activity
KR75_RS00960	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
KR75_RS00965	COG1090	epimerase
KR75_RS00975	COG4598	ABC transporter
KR75_RS00980	COG4160	amino acid transport
KR75_RS01000	COG0163	prenyltransferase activity
KR75_RS01005	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
KR75_RS01010	COG1286	toxin biosynthetic process
KR75_RS01015	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
KR75_RS01020	COG0285	dihydrofolate synthase activity
KR75_RS01030	COG0586	Pfam SNARE associated Golgi protein
KR75_RS01040	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
KR75_RS01065	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
KR75_RS01075	COG2188	Transcriptional regulator
KR75_RS01085	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
KR75_RS01100	COG3101	peptidyl-lysine hydroxylation
KR75_RS01105	COG0730	response to heat
KR75_RS01130	COG2062	phosphohistidine phosphatase, SixA
KR75_RS01145	COG3691	Protein conserved in bacteria
KR75_RS01155	COG2853	Lipoprotein
KR75_RS01160	COG2116	formate transmembrane transporter activity
KR75_RS01180	COG0583	DNA-binding transcription factor activity
KR75_RS01185	COG0590	tRNA wobble adenosine to inosine editing
KR75_RS01190	COG2807	transmembrane transport
KR75_RS01195	COG0436	Aminotransferase
KR75_RS01205	COG3275	phosphorelay sensor kinase activity
KR75_RS01210	COG3279	Response regulator of the LytR AlgR family
KR75_RS01225	COG3961	Belongs to the TPP enzyme family
KR75_RS01230	COG0667	Aldo Keto reductase
KR75_RS01245	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KR75_RS01250	COG2200	EAL domain
KR75_RS01250	COG2199	diguanylate cyclase activity
KR75_RS01265	COG3415	Transposase
KR75_RS01270	COG3415	Transposase
KR75_RS01305	COG0583	DNA-binding transcription factor activity
KR75_RS01310	COG0385	Bile acid
KR75_RS01315	COG3530	Putative quorum-sensing-regulated virulence factor
KR75_RS01335	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
KR75_RS01370	COG4319	ketosteroid isomerase
KR75_RS01380	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
KR75_RS01385	COG4208	sulfate ABC transporter
KR75_RS01390	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
KR75_RS01395	COG4150	thiosulfate binding
KR75_RS01400	COG2837	iron assimilation
KR75_RS01420	COG0860	N-Acetylmuramoyl-L-alanine amidase
KR75_RS01480	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
KR75_RS01510	COG4810	utilization protein
KR75_RS01520	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
KR75_RS01525	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
KR75_RS01530	COG5342	invasion associated locus B
KR75_RS01540	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
KR75_RS01540	COG0493	'glutamate synthase
KR75_RS01545	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KR75_RS01550	COG1393	Belongs to the ArsC family
KR75_RS01565	COG0400	carboxylic ester hydrolase activity
KR75_RS01570	COG1444	tRNA N-acetyltransferase activity
KR75_RS01575	COG2321	neutral zinc metallopeptidase
KR75_RS01585	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
KR75_RS01595	COG2716	regulation of RNA biosynthetic process
KR75_RS01600	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
KR75_RS01605	COG0628	permease
KR75_RS01610	COG4783	chaperone-mediated protein folding
KR75_RS01615	COG1393	Belongs to the ArsC family
KR75_RS01630	COG2233	PERMEase
KR75_RS01640	COG2723	6-phospho-beta-galactosidase activity
KR75_RS01655	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
KR75_RS01670	COG2200	EAL domain
KR75_RS01695	COG0517	IMP dehydrogenase activity
KR75_RS01695	COG0516	GMP reductase activity
KR75_RS01705	COG1645	bacterial-type flagellum-dependent swarming motility
KR75_RS01725	COG2976	Protein conserved in bacteria
KR75_RS01755	COG4953	penicillin-binding protein 1C
KR75_RS01760	COG2373	Large extracellular alpha-helical protein
KR75_RS01765	COG2897	thiosulfate sulfurtransferase activity
KR75_RS01785	COG2975	iron-sulfur cluster assembly
KR75_RS01790	COG0633	Ferredoxin
KR75_RS01810	COG0822	iron-sulfur transferase activity
KR75_RS01840	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
KR75_RS01845	COG3683	transport system, periplasmic component
KR75_RS01850	COG3711	transcriptional antiterminator
KR75_RS01855	COG2814	Major facilitator Superfamily
KR75_RS01860	COG2259	Doxx family
KR75_RS01870	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
KR75_RS01870	COG1017	nitric oxide dioxygenase activity
KR75_RS01875	COG0347	Belongs to the P(II) protein family
KR75_RS01880	COG2204	response regulator
KR75_RS01885	COG3170	Tfp pilus assembly protein FimV
KR75_RS01890	COG2205	protein histidine kinase activity
KR75_RS01895	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KR75_RS01895	COG0047	phosphoribosylformylglycinamidine synthase activity
KR75_RS01910	COG0560	Phosphoserine phosphatase
KR75_RS01915	COG1737	Transcriptional regulator
KR75_RS01920	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
KR75_RS01930	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
KR75_RS01955	COG0681	Belongs to the peptidase S26 family
KR75_RS01965	COG3086	response to oxidative stress
KR75_RS01970	COG3026	antisigma factor binding
KR75_RS01975	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
KR75_RS01985	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
KR75_RS01995	COG0513	Belongs to the DEAD box helicase family
KR75_RS02010	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KR75_RS02015	COG3118	belongs to the thioredoxin family
KR75_RS02020	COG3148	PFAM DTW domain containing protein
KR75_RS02030	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KR75_RS02035	COG5544	Lipoprotein
KR75_RS02040	COG0477	Major facilitator Superfamily
KR75_RS02075	COG0542	response to heat
KR75_RS02090	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
KR75_RS02095	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
KR75_RS02110	COG1605	Chorismate mutase
KR75_RS02110	COG0287	Prephenate dehydrogenase
KR75_RS02115	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
KR75_RS02125	COG2199	diguanylate cyclase activity
KR75_RS02130	COG2885	chlorophyll binding
KR75_RS02165	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
KR75_RS02170	COG4137	Cytochrome C assembly protein
KR75_RS02175	COG4536	flavin adenine dinucleotide binding
KR75_RS02190	COG0497	DNA recombination
KR75_RS02205	COG2867	negative regulation of translational initiation
KR75_RS02215	COG0582	viral genome integration into host DNA
KR75_RS02225	COG1475	DNA binding
KR75_RS02320	COG4974	Belongs to the 'phage' integrase family
KR75_RS02350	COG3708	Transcriptional regulator
KR75_RS02350	COG2207	Transcriptional regulator
KR75_RS02355	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KR75_RS02430	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KR75_RS02435	COG1126	abc transporter atp-binding protein
KR75_RS02440	COG0235	Class ii aldolase
KR75_RS02450	COG1028	Short-chain dehydrogenase reductase Sdr
KR75_RS02490	COG3121	Chaperone
KR75_RS02505	COG3284	Transcriptional regulator
KR75_RS02510	COG0671	phosphoesterase, PA-phosphatase related
KR75_RS02515	COG0583	DNA-binding transcription factor activity
KR75_RS02525	COG0640	Transcriptional regulator
KR75_RS02530	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KR75_RS02560	COG4575	ribosome binding
KR75_RS02570	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
KR75_RS02575	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
KR75_RS02585	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KR75_RS02600	COG4176	ABC-type proline glycine betaine transport system permease component
KR75_RS02610	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
KR75_RS02620	COG1846	Transcriptional regulator
KR75_RS02625	COG1566	PFAM secretion protein HlyD family protein
KR75_RS02630	COG2814	Major facilitator Superfamily
KR75_RS02635	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
KR75_RS02655	COG1238	metal cluster binding
KR75_RS02660	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
KR75_RS02665	COG2823	Periplasmic or secreted lipoprotein
KR75_RS02695	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
KR75_RS02715	COG1546	Belongs to the CinA family
KR75_RS02720	COG0803	Belongs to the bacterial solute-binding protein 9 family
KR75_RS02725	COG1108	ABC-type Mn2 Zn2 transport systems permease components
KR75_RS02730	COG1121	(ABC) transporter
KR75_RS02735	COG2951	lytic endotransglycosylase activity
KR75_RS02740	COG3730	PTS system glucitol sorbitol-specific
KR75_RS02745	COG3732	PTS system glucitol sorbitol-specific
KR75_RS02755	COG1028	Short-chain dehydrogenase reductase Sdr
KR75_RS02760	COG4578	phosphoenolpyruvate-dependent sugar phosphotransferase system
KR75_RS02765	COG1349	DNA-binding transcription factor activity
KR75_RS02790	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
KR75_RS02795	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
KR75_RS02800	COG1414	Transcriptional regulator
KR75_RS02810	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
KR75_RS02815	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
KR75_RS02820	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
KR75_RS02825	COG1609	Transcriptional regulator
KR75_RS02835	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KR75_RS02835	COG1263	PTS System
KR75_RS02840	COG2723	6-phospho-beta-galactosidase activity
KR75_RS02850	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
KR75_RS02860	COG3260	NADH ubiquinone oxidoreductase 20
KR75_RS02865	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
KR75_RS02870	COG3261	NADH dehydrogenase
KR75_RS02870	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
KR75_RS02875	COG0650	Formate hydrogenlyase subunit 4
KR75_RS02880	COG0651	ATP synthesis coupled electron transport
KR75_RS02885	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
KR75_RS02900	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
KR75_RS02905	COG0298	carbon dioxide binding
KR75_RS02910	COG0409	Hydrogenase expression formation protein
KR75_RS02915	COG0309	Hydrogenase expression formation protein (HypE)
KR75_RS02925	COG2723	6-phospho-beta-galactosidase activity
KR75_RS02935	COG4580	involved in the transport of maltose and maltodextrins
KR75_RS02940	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
KR75_RS02945	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
KR75_RS02950	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
KR75_RS02955	COG1447	Phosphotransferase system cellobiose-specific component IIA
KR75_RS02960	COG1940	carbohydrate kinase activity
KR75_RS02965	COG1609	Transcriptional regulator
KR75_RS02975	COG1121	(ABC) transporter
KR75_RS02980	COG1108	ABC-type Mn2 Zn2 transport systems permease components
KR75_RS02985	COG1108	ABC-type Mn2 Zn2 transport systems permease components
KR75_RS03000	COG0679	Auxin Efflux Carrier
KR75_RS03020	COG3720	iron ion transport
KR75_RS03025	COG4558	Periplasmic binding protein
KR75_RS03030	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KR75_RS03065	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
KR75_RS03070	COG0163	prenyltransferase activity
KR75_RS03095	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KR75_RS03160	COG2234	aminopeptidase activity
KR75_RS03180	COG0720	synthase
KR75_RS03185	COG0602	queuosine metabolic process
KR75_RS03205	COG3956	TIGRFAM MazG family protein
KR75_RS03215	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
KR75_RS03225	COG3437	response regulator, receiver
KR75_RS03225	COG2205	protein histidine kinase activity
KR75_RS03225	COG3850	Histidine kinase
KR75_RS03225	COG4999	Histidine kinase
KR75_RS03230	COG1929	Belongs to the glycerate kinase type-1 family
KR75_RS03235	COG4948	Mandelate Racemase Muconate Lactonizing
KR75_RS03240	COG4948	Mandelate Racemase Muconate Lactonizing
KR75_RS03245	COG2271	Major facilitator Superfamily
KR75_RS03250	COG0716	FMN binding
KR75_RS03255	COG0564	pseudouridine synthase activity
KR75_RS03260	COG3098	single-species biofilm formation
KR75_RS03275	COG1611	Belongs to the LOG family
KR75_RS03280	COG0814	amino acid
KR75_RS03285	COG1760	l-serine dehydratase
KR75_RS03290	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KR75_RS03300	COG0477	Major facilitator Superfamily
KR75_RS03305	COG1464	Belongs to the NlpA lipoprotein family
KR75_RS03310	COG2011	ABC-type metal ion transport system permease component
KR75_RS03315	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KR75_RS03330	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KR75_RS03345	COG1454	alcohol dehydrogenase
KR75_RS03350	COG0235	Class ii aldolase
KR75_RS03355	COG0738	Major facilitator superfamily
KR75_RS03375	COG1349	DNA-binding transcription factor activity
KR75_RS03385	COG2363	Small membrane protein
KR75_RS03390	COG0583	DNA-binding transcription factor activity
KR75_RS03400	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
KR75_RS03405	COG2166	iron-sulfur cluster assembly
KR75_RS03410	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
KR75_RS03415	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
KR75_RS03580	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
KR75_RS03610	COG1012	belongs to the aldehyde dehydrogenase family
KR75_RS03610	COG1454	alcohol dehydrogenase
KR75_RS03615	COG4656	Part of a membrane complex involved in electron transport
KR75_RS03645	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
KR75_RS03650	COG0860	N-Acetylmuramoyl-L-alanine amidase
KR75_RS03655	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
KR75_RS03655	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
KR75_RS03665	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
KR75_RS03670	COG1074	ATP-dependent DNA helicase activity
KR75_RS03675	COG1025	Belongs to the peptidase M16 family
KR75_RS03680	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
KR75_RS03685	COG4967	type IV pilus modification protein PilV
KR75_RS03695	COG4795	General secretion pathway protein
KR75_RS03700	COG2165	general secretion pathway protein
KR75_RS03730	COG0861	Integral membrane protein TerC family
KR75_RS03740	COG0667	Aldo Keto reductase
KR75_RS03760	COG1609	Transcriptional regulator
KR75_RS03770	COG2186	Transcriptional regulator
KR75_RS03775	COG2723	6-phospho-beta-galactosidase activity
KR75_RS03780	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
KR75_RS03785	COG1609	Transcriptional regulator
KR75_RS03795	COG0583	DNA-binding transcription factor activity
KR75_RS03800	COG1794	racemase activity, acting on amino acids and derivatives
KR75_RS03805	COG1917	Cupin 2, conserved barrel domain protein
KR75_RS03810	COG1175	transmembrane transport
KR75_RS03815	COG0395	ABC-type sugar transport system, permease component
KR75_RS03820	COG3842	ATPase activity
KR75_RS03850	COG2814	Major facilitator Superfamily
KR75_RS03855	COG1028	Short-chain dehydrogenase reductase Sdr
KR75_RS03860	COG0823	Involved in the tonB-independent uptake of proteins
KR75_RS03870	COG0183	Belongs to the thiolase family
KR75_RS03885	COG0814	amino acid
KR75_RS03890	COG0667	Aldo Keto reductase
KR75_RS03940	COG0697	spore germination
KR75_RS03945	COG1846	Transcriptional regulator
KR75_RS03950	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
KR75_RS03960	COG3188	usher protein
KR75_RS03965	COG3121	Chaperone
KR75_RS03990	COG0582	viral genome integration into host DNA
KR75_RS03995	COG4974	Belongs to the 'phage' integrase family
KR75_RS04005	COG3539	Fimbrial protein
KR75_RS04010	COG3121	Chaperone
KR75_RS04015	COG3188	usher protein
KR75_RS04020	COG3539	Fimbrial protein
KR75_RS04025	COG3539	Fimbrial protein
KR75_RS04030	COG3539	Fimbrial protein
KR75_RS04040	COG2388	GCN5-related N-acetyl-transferase
KR75_RS04045	COG3592	Divergent 4Fe-4S mono-cluster
KR75_RS04060	COG1289	transmembrane transporter activity
KR75_RS04065	COG1538	Outer membrane efflux protein
KR75_RS04080	COG1393	Belongs to the ArsC family
KR75_RS04085	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
KR75_RS04120	COG2249	NAD(P)H dehydrogenase (quinone) activity
KR75_RS04125	COG0667	Aldo Keto reductase
KR75_RS04135	COG0583	DNA-binding transcription factor activity
KR75_RS04140	COG2814	Major facilitator Superfamily
KR75_RS04150	COG4942	peptidase
KR75_RS04170	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
KR75_RS04180	COG4974	Belongs to the 'phage' integrase family
KR75_RS04185	COG0716	FMN binding
KR75_RS04195	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
KR75_RS04205	COG1272	protein, Hemolysin III
KR75_RS04215	COG1737	Transcriptional regulator
KR75_RS04220	COG2723	6-phospho-beta-galactosidase activity
KR75_RS04240	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KR75_RS04245	COG1028	Short-chain dehydrogenase reductase Sdr
KR75_RS04265	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KR75_RS04270	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KR75_RS04275	COG0006	proline dipeptidase activity
KR75_RS04290	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
KR75_RS04295	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
KR75_RS04310	COG2968	Membrane
KR75_RS04320	COG0668	transmembrane transport
KR75_RS04325	COG0191	fructose-bisphosphate aldolase activity
KR75_RS04340	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
KR75_RS04345	COG0501	Belongs to the peptidase M48B family
KR75_RS04370	COG2814	Major facilitator Superfamily
KR75_RS04380	COG2356	endonuclease I
KR75_RS04385	COG1385	rRNA (uridine-N3-)-methyltransferase activity
KR75_RS04390	COG0189	ligase activity
KR75_RS04410	COG2805	Type II/IV secretion system protein
KR75_RS04415	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
KR75_RS04420	COG0762	integral membrane protein
KR75_RS04435	COG0635	Involved in the biosynthesis of porphyrin-containing compound
KR75_RS04445	COG3171	Protein conserved in bacteria
KR75_RS04455	COG1194	a g-specific adenine glycosylase
KR75_RS04470	COG2211	Major facilitator Superfamily
KR75_RS04475	COG1982	Orn Lys Arg decarboxylase major
KR75_RS04480	COG1811	Na channel or pump
KR75_RS04535	COG0626	cystathionine gamma-synthase activity
KR75_RS04560	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KR75_RS04565	COG0754	glutathionylspermidine amidase activity
KR75_RS04575	COG0625	glutathione transferase activity
KR75_RS04595	COG0848	biopolymer transport protein
KR75_RS04605	COG0626	cystathionine gamma-synthase activity
KR75_RS04610	COG0586	Pfam SNARE associated Golgi protein
KR75_RS04615	COG2207	Transcriptional regulator
KR75_RS04620	COG1979	alcohol dehydrogenase
KR75_RS04625	COG0656	L-ascorbic acid biosynthetic process
KR75_RS04630	COG1032	radical SAM domain protein
KR75_RS04635	COG2132	Multicopper oxidase
KR75_RS04640	COG0204	Acyl-transferase
KR75_RS04645	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KR75_RS04650	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
KR75_RS04655	COG3111	PFAM Bacterial OB fold (BOF) protein
KR75_RS04665	COG0642	Histidine kinase
KR75_RS04670	COG2249	NAD(P)H dehydrogenase (quinone) activity
KR75_RS04675	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
KR75_RS04685	COG3150	esterase
KR75_RS04690	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
KR75_RS04695	COG3151	Protein conserved in bacteria
KR75_RS04700	COG0494	nUDIX hydrolase
KR75_RS04715	COG0754	glutathionylspermidine amidase activity
KR75_RS04720	COG3384	dioxygenase
KR75_RS04735	COG2960	long-chain fatty acid transporting porin activity
KR75_RS04755	COG3025	triphosphatase activity
KR75_RS04760	COG4991	sh3 domain protein
KR75_RS04775	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
KR75_RS04830	COG0828	Belongs to the bacterial ribosomal protein bS21 family
KR75_RS04835	COG0358	DNA primase activity
KR75_RS04840	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KR75_RS04860	COG1773	rubredoxin
KR75_RS04860	COG0426	domain, Protein
KR75_RS04875	COG2197	response regulator
KR75_RS04880	COG2205	protein histidine kinase activity
KR75_RS04880	COG2198	Histidine kinase
KR75_RS04880	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KR75_RS04880	COG0784	Response regulator, receiver
KR75_RS04890	COG3247	response to pH
KR75_RS04910	COG2376	Dihydroxyacetone kinase
KR75_RS04915	COG1461	Dihydroxyacetone kinase
KR75_RS04930	COG2375	cellular response to nickel ion
KR75_RS04935	COG1695	Transcriptional regulator
KR75_RS04985	COG0446	pyridine nucleotide-disulphide oxidoreductase
KR75_RS04985	COG1902	pentaerythritol trinitrate reductase activity
KR75_RS04995	COG2211	Major facilitator Superfamily
KR75_RS05005	COG3507	Belongs to the glycosyl hydrolase 43 family
KR75_RS05010	COG1451	nucleotide metabolic process
KR75_RS05015	COG0673	inositol 2-dehydrogenase activity
KR75_RS05020	COG0861	Integral membrane protein TerC family
KR75_RS05035	COG2721	sulfolactate sulfo-lyase activity
KR75_RS05045	COG2271	Major facilitator Superfamily
KR75_RS05050	COG2186	Transcriptional regulator
KR75_RS05055	COG0586	Pfam SNARE associated Golgi protein
KR75_RS05065	COG1422	Protein of unknown function (DUF1090)
KR75_RS05070	COG4575	ribosome binding
KR75_RS05075	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
KR75_RS05080	COG2259	Doxx family
KR75_RS05085	COG0435	Glutathione S-transferase
KR75_RS05090	COG3152	Membrane
KR75_RS05095	COG0583	DNA-binding transcription factor activity
KR75_RS05100	COG1741	Belongs to the pirin family
KR75_RS05115	COG1929	Belongs to the glycerate kinase type-1 family
KR75_RS05120	COG2084	Dehydrogenase
KR75_RS05130	COG2271	Major facilitator Superfamily
KR75_RS05135	COG2721	sulfolactate sulfo-lyase activity
KR75_RS05140	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KR75_RS05145	COG1349	DNA-binding transcription factor activity
KR75_RS05155	COG1105	Belongs to the carbohydrate kinase PfkB family
KR75_RS05160	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
KR75_RS05160	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KR75_RS05160	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KR75_RS05165	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
KR75_RS05165	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
KR75_RS05175	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
KR75_RS05180	COG3414	Phosphotransferase system galactitol-specific IIB component
KR75_RS05185	COG3775	system Galactitol-specific IIC component
KR75_RS05190	COG1063	alcohol dehydrogenase
KR75_RS05205	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
KR75_RS05225	COG2823	Periplasmic or secreted lipoprotein
KR75_RS05230	COG0701	Predicted permease
KR75_RS05235	COG0702	epimerase
KR75_RS05240	COG0693	protein deglycase activity
KR75_RS05255	COG3153	acetyltransferase
KR75_RS05260	COG3154	lipid carrier protein
KR75_RS05265	COG0826	peptidase U32
KR75_RS05270	COG0826	peptidase U32
KR75_RS05275	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KR75_RS05280	COG0814	amino acid
KR75_RS05325	COG0195	Participates in both transcription termination and antitermination
KR75_RS05365	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
KR75_RS05375	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
KR75_RS05380	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KR75_RS05390	COG1534	Rna-binding protein
KR75_RS05400	COG2027	D-alanyl-D-alanine carboxypeptidase
KR75_RS05410	COG0697	spore germination
KR75_RS05425	COG0142	geranyltranstransferase activity
KR75_RS05430	COG3423	Transcriptional regulator
KR75_RS05440	COG5007	Belongs to the BolA IbaG family
KR75_RS05445	COG3113	response to antibiotic
KR75_RS05450	COG2854	intermembrane phospholipid transfer
KR75_RS05455	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
KR75_RS05460	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
KR75_RS05465	COG1127	ABC transporter
KR75_RS05470	COG0530	calcium, potassium:sodium antiporter activity
KR75_RS05480	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
KR75_RS05485	COG3117	lipopolysaccharide transmembrane transporter activity
KR75_RS05490	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
KR75_RS05495	COG1137	ATPase activity
KR75_RS05500	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
KR75_RS05505	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
KR75_RS05510	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
KR75_RS05520	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
KR75_RS05525	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KR75_RS05530	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
KR75_RS05535	COG5002	protein histidine kinase activity
KR75_RS05535	COG0784	Response regulator, receiver
KR75_RS05535	COG2198	Histidine kinase
KR75_RS05540	COG1312	Catalyzes the dehydration of D-mannonate
KR75_RS05545	COG1063	alcohol dehydrogenase
KR75_RS05550	COG2271	Major facilitator Superfamily
KR75_RS05555	COG1242	4 iron, 4 sulfur cluster binding
KR75_RS05560	COG0070	glutamate synthase
KR75_RS05560	COG0069	glutamate synthase activity
KR75_RS05560	COG0067	glutamate synthase
KR75_RS05565	COG0493	'glutamate synthase
KR75_RS05575	COG2969	positive regulation of protein catabolic process
KR75_RS05580	COG0625	glutathione transferase activity
KR75_RS05595	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
KR75_RS05600	COG3105	Protein conserved in bacteria
KR75_RS05605	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KR75_RS05610	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KR75_RS05625	COG5016	pyruvate
KR75_RS05625	COG0511	ligase activity, forming carbon-carbon bonds
KR75_RS05635	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
KR75_RS05640	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
KR75_RS05645	COG0471	metal ion transport
KR75_RS05655	COG1802	Transcriptional regulator
KR75_RS05680	COG2732	(Barnase) inhibitor
KR75_RS05685	COG1289	transmembrane transporter activity
KR75_RS05700	COG0583	DNA-binding transcription factor activity
KR75_RS05705	COG0312	modulator of DNA gyrase
KR75_RS05710	COG3164	Protein of unknown function
KR75_RS05715	COG1530	ribonuclease E activity
KR75_RS05725	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
KR75_RS05730	COG1792	Involved in formation and maintenance of cell shape
KR75_RS05735	COG1077	Cell shape determining protein MreB Mrl
KR75_RS05740	COG2200	EAL domain
KR75_RS05740	COG2199	diguanylate cyclase activity
KR75_RS05765	COG0511	ligase activity, forming carbon-carbon bonds
KR75_RS05770	COG0439	Biotin carboxylase
KR75_RS05775	COG3924	membrane
KR75_RS05780	COG4145	pantothenate transmembrane transporter activity
KR75_RS05805	COG1309	transcriptional regulator
KR75_RS05810	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KR75_RS05815	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KR75_RS05845	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
KR75_RS05865	COG0551	DNA topoisomerase type I activity
KR75_RS05875	COG0758	DNA mediated transformation
KR75_RS05905	COG0789	Transcriptional regulator
KR75_RS05920	COG0202	RNA polymerase activity
KR75_RS05930	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
KR75_RS05940	COG0201	protein transport
KR75_RS06005	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
KR75_RS06020	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
KR75_RS06045	COG0051	transcription antitermination factor activity, RNA binding
KR75_RS06095	COG2964	Protein conserved in bacteria
KR75_RS06100	COG0545	Peptidyl-prolyl cis-trans isomerase
KR75_RS06110	COG1047	Peptidyl-prolyl cis-trans
KR75_RS06115	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
KR75_RS06130	COG0488	(ABC) transporter
KR75_RS06135	COG0429	hydrolase of the alpha beta-hydrolase fold
KR75_RS06145	COG3954	Phosphoribulokinase
KR75_RS06150	COG1765	OsmC-like protein
KR75_RS06160	COG1289	transmembrane transporter activity
KR75_RS06165	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
KR75_RS06185	COG0738	Major facilitator superfamily
KR75_RS06190	COG0402	S-adenosylhomocysteine deaminase activity
KR75_RS06195	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KR75_RS06220	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
KR75_RS06225	COG0338	D12 class N6 adenine-specific DNA methyltransferase
KR75_RS06230	COG3266	domain, Protein
KR75_RS06245	COG4796	Type ii and iii secretion system protein
KR75_RS06270	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
KR75_RS06275	COG0494	nUDIX hydrolase
KR75_RS06285	COG1011	Hydrolase
KR75_RS06290	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
KR75_RS06315	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
KR75_RS06320	COG2183	response to ionizing radiation
KR75_RS06325	COG1918	ferrous iron import across plasma membrane
KR75_RS06350	COG1040	competence protein
KR75_RS06360	COG2610	gluconate transmembrane transporter activity
KR75_RS06365	COG1640	4-alpha-glucanotransferase
KR75_RS06370	COG0058	SHG alpha-glucan phosphorylase activity
KR75_RS06380	COG1349	DNA-binding transcription factor activity
KR75_RS06395	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
KR75_RS06410	COG0058	SHG alpha-glucan phosphorylase activity
KR75_RS06435	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
KR75_RS06440	COG2610	gluconate transmembrane transporter activity
KR75_RS06445	COG3265	gluconokinase activity
KR75_RS06450	COG1609	Transcriptional regulator
KR75_RS06455	COG1741	Belongs to the pirin family
KR75_RS06460	COG0673	inositol 2-dehydrogenase activity
KR75_RS06470	COG1247	-acetyltransferase
KR75_RS06475	COG0405	Gamma-glutamyltransferase
KR75_RS06485	COG0584	glycerophosphoryl diester phosphodiesterase
KR75_RS06535	COG0559	Belongs to the binding-protein-dependent transport system permease family
KR75_RS06540	COG0683	leucine binding
KR75_RS06555	COG0683	leucine binding
KR75_RS06565	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
KR75_RS06580	COG2177	Part of the ABC transporter FtsEX involved in
KR75_RS06585	COG2884	Cell division ATP-binding protein ftsE
KR75_RS06590	COG0552	protein localization to endoplasmic reticulum
KR75_RS06595	COG0742	ribosomal rna small subunit methyltransferase
KR75_RS06600	COG3776	membrane
KR75_RS06610	COG3714	YhhN family
KR75_RS06625	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
KR75_RS06635	COG0477	Major facilitator Superfamily
KR75_RS06640	COG0628	permease
KR75_RS06680	COG3479	Phenolic acid decarboxylase
KR75_RS06690	COG0747	negative chemotaxis
KR75_RS06695	COG0601	transmembrane transport
KR75_RS06700	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KR75_RS06710	COG1124	(ABC) transporter
KR75_RS06720	COG2239	Acts as a magnesium transporter
KR75_RS06725	COG2081	HI0933 family
KR75_RS06730	COG0306	phosphate transporter
KR75_RS06740	COG0589	response to stress
KR75_RS06760	COG0671	phosphoesterase, PA-phosphatase related
KR75_RS06765	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
KR75_RS06770	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KR75_RS06780	COG1454	alcohol dehydrogenase
KR75_RS06790	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KR75_RS06795	COG1028	Short-chain dehydrogenase reductase Sdr
KR75_RS06800	COG0583	DNA-binding transcription factor activity
KR75_RS06805	COG1295	ribonuclease BN
KR75_RS06810	COG0477	Major facilitator Superfamily
KR75_RS06815	COG2982	Protein involved in outer membrane biogenesis
KR75_RS06825	COG0612	Peptidase, M16
KR75_RS06835	COG2200	EAL domain
KR75_RS06835	COG2199	diguanylate cyclase activity
KR75_RS06840	COG3118	belongs to the thioredoxin family
KR75_RS06840	COG0457	Tetratricopeptide repeat
KR75_RS06845	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
KR75_RS06880	COG2194	sulfuric ester hydrolase activity
KR75_RS06895	COG0457	Tetratricopeptide repeat
KR75_RS06900	COG1215	transferase activity, transferring glycosyl groups
KR75_RS06910	COG2894	cell division
KR75_RS06920	COG4608	Belongs to the ABC transporter superfamily
KR75_RS06925	COG0444	Belongs to the ABC transporter superfamily
KR75_RS06930	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KR75_RS06935	COG0601	transmembrane transport
KR75_RS06940	COG0747	negative chemotaxis
KR75_RS06965	COG2223	nitrite transmembrane transporter activity
KR75_RS06970	COG5571	outer membrane autotransporter
KR75_RS06975	COG2818	Glycosylase
KR75_RS06980	COG0456	acetyltransferase
KR75_RS06985	COG0243	molybdopterin cofactor binding
KR75_RS06990	COG2885	chlorophyll binding
KR75_RS06995	COG1609	Transcriptional regulator
KR75_RS07005	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KR75_RS07025	COG2814	Major facilitator Superfamily
KR75_RS07030	COG2944	sequence-specific DNA binding
KR75_RS07035	COG1278	Cold shock
KR75_RS07040	COG0488	(ABC) transporter
KR75_RS07065	COG3274	enterobacterial common antigen metabolic process
KR75_RS07070	COG4682	membrane
KR75_RS07075	COG4682	membrane
KR75_RS07090	COG4213	ABC transporter substrate-binding protein
KR75_RS07100	COG4214	carbohydrate transport
KR75_RS07105	COG2207	Transcriptional regulator
KR75_RS07105	COG1609	Transcriptional regulator
KR75_RS07110	COG2992	FlgJ-related protein
KR75_RS07115	COG0366	Alpha amylase catalytic
KR75_RS07120	COG3977	Valine--pyruvate aminotransferase
KR75_RS07125	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
KR75_RS07130	COG1414	Transcriptional regulator
KR75_RS07140	COG2731	YhcH YjgK YiaL family protein
KR75_RS07150	COG2271	Major facilitator Superfamily
KR75_RS07155	COG1070	Carbohydrate kinase
KR75_RS07160	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
KR75_RS07165	COG3623	hexulose-6-phosphate isomerase
KR75_RS07170	COG0235	Class ii aldolase
KR75_RS07175	COG3276	selenocysteine insertion sequence binding
KR75_RS07185	COG0625	glutathione transferase activity
KR75_RS07190	COG1566	PFAM secretion protein HlyD family protein
KR75_RS07210	COG3722	fumarate hydratase activity
KR75_RS07230	COG2186	Transcriptional regulator
KR75_RS07240	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
KR75_RS07260	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
KR75_RS07265	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KR75_RS07275	COG4942	peptidase
KR75_RS07280	COG2861	carbohydrate metabolic process
KR75_RS07285	COG0463	Glycosyl transferase, family 2
KR75_RS07295	COG0156	8-amino-7-oxononanoate synthase activity
KR75_RS07310	COG0859	PFAM glycosyl transferase family 9
KR75_RS07335	COG0859	PFAM glycosyl transferase family 9
KR75_RS07345	COG0438	transferase activity, transferring glycosyl groups
KR75_RS07350	COG1216	Glycosyl transferase, family 2
KR75_RS07355	COG1519	Transferase
KR75_RS07380	COG0227	Belongs to the bacterial ribosomal protein bL28 family
KR75_RS07390	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
KR75_RS07425	COG1131	(ABC) transporter
KR75_RS07440	COG1561	YicC-like family, N-terminal region
KR75_RS07450	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
KR75_RS07450	COG2169	Transcriptional regulator
KR75_RS07460	COG2860	membrane
KR75_RS07485	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
KR75_RS07490	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KR75_RS07495	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
KR75_RS07500	COG1494	fructose-1,6-bisphosphatase
KR75_RS07510	COG3152	Membrane
KR75_RS07535	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
KR75_RS07540	COG3074	FtsZ-dependent cytokinesis
KR75_RS07555	COG0786	glutamate:sodium symporter activity
KR75_RS07560	COG2233	PERMEase
KR75_RS07565	COG2982	Protein involved in outer membrane biogenesis
KR75_RS07570	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KR75_RS07570	COG1263	PTS System
KR75_RS07575	COG1486	melibiose metabolic process
KR75_RS07585	COG1501	Belongs to the glycosyl hydrolase 31 family
KR75_RS07590	COG2211	Major facilitator Superfamily
KR75_RS07620	COG1064	alcohol dehydrogenase
KR75_RS07630	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
KR75_RS07645	COG1464	Belongs to the NlpA lipoprotein family
KR75_RS07670	COG0583	DNA-binding transcription factor activity
KR75_RS07680	COG1309	transcriptional regulator
KR75_RS07700	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KR75_RS07710	COG2814	Major facilitator Superfamily
KR75_RS07720	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KR75_RS07720	COG1263	PTS System
KR75_RS07725	COG0697	spore germination
KR75_RS07740	COG2828	Protein conserved in bacteria
KR75_RS07745	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
KR75_RS07750	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
KR75_RS07755	COG0583	DNA-binding transcription factor activity
KR75_RS07760	COG3384	dioxygenase
KR75_RS07770	COG1609	Transcriptional regulator
KR75_RS07780	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
KR75_RS07780	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
KR75_RS07785	COG1447	Phosphotransferase system cellobiose-specific component IIA
KR75_RS07790	COG4580	involved in the transport of maltose and maltodextrins
KR75_RS07820	COG2271	Major facilitator Superfamily
KR75_RS07830	COG2197	response regulator
KR75_RS07835	COG0440	acetolactate synthase activity
KR75_RS07840	COG0028	Belongs to the TPP enzyme family
KR75_RS07855	COG2814	Major facilitator Superfamily
KR75_RS07860	COG0583	DNA-binding transcription factor activity
KR75_RS07865	COG2610	gluconate transmembrane transporter activity
KR75_RS07875	COG0641	radical SAM
KR75_RS07885	COG2149	membrane
KR75_RS07900	COG2188	Transcriptional regulator
KR75_RS07920	COG5645	(Lipo)protein
KR75_RS07925	COG0823	Involved in the tonB-independent uptake of proteins
KR75_RS07940	COG0561	phosphatase activity
KR75_RS07995	COG2091	lysine biosynthetic process via aminoadipic acid
KR75_RS08000	COG0431	NADPH-dependent FMN reductase
KR75_RS08005	COG2252	PERMEase
KR75_RS08010	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
KR75_RS08015	COG0363	glucosamine-6-phosphate deaminase activity
KR75_RS08020	COG2382	esterase
KR75_RS08030	COG0704	Plays a role in the regulation of phosphate uptake
KR75_RS08035	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
KR75_RS08040	COG0581	inorganic phosphate transmembrane transporter activity
KR75_RS08045	COG0573	inorganic phosphate transmembrane transporter activity
KR75_RS08050	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
KR75_RS08055	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
KR75_RS08105	COG3312	ion transport
KR75_RS08120	COG0716	FMN binding
KR75_RS08125	COG1522	sequence-specific DNA binding
KR75_RS08155	COG1129	ABC transporter
KR75_RS08160	COG1172	Belongs to the binding-protein-dependent transport system permease family
KR75_RS08170	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KR75_RS08175	COG1609	Transcriptional regulator
KR75_RS08180	COG0477	Major facilitator Superfamily
KR75_RS08185	COG2186	Transcriptional regulator
KR75_RS08210	COG1763	Mo-molybdopterin cofactor biosynthetic process
KR75_RS08220	COG3084	Protein conserved in bacteria
KR75_RS08225	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
KR75_RS08235	COG0204	Acyl-transferase
KR75_RS08255	COG0635	Involved in the biosynthesis of porphyrin-containing compound
KR75_RS08265	COG3852	Histidine kinase
KR75_RS08280	COG1011	Hydrolase
KR75_RS08295	COG0456	acetyltransferase
KR75_RS08300	COG0657	acetylesterase activity
KR75_RS08305	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
KR75_RS08320	COG2864	formate dehydrogenase
KR75_RS08325	COG0437	4 iron, 4 sulfur cluster binding
KR75_RS08330	COG3383	formate dehydrogenase (NAD+) activity
KR75_RS08330	COG0243	molybdopterin cofactor binding
KR75_RS08335	COG3383	formate dehydrogenase (NAD+) activity
KR75_RS08335	COG0243	molybdopterin cofactor binding
KR75_RS08350	COG0205	6-phosphofructokinase activity
KR75_RS08410	COG2211	Major facilitator Superfamily
KR75_RS08415	COG1609	Transcriptional regulator
KR75_RS08420	COG2211	Major facilitator Superfamily
KR75_RS08435	COG1454	alcohol dehydrogenase
KR75_RS08440	COG1172	Belongs to the binding-protein-dependent transport system permease family
KR75_RS08445	COG1172	Belongs to the binding-protein-dependent transport system permease family
KR75_RS08450	COG1129	ABC transporter
KR75_RS08490	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
KR75_RS08495	COG2258	MOSC domain
KR75_RS08500	COG2205	protein histidine kinase activity
KR75_RS08505	COG0745	RESPONSE REGULATOR receiver
KR75_RS08510	COG3678	ATP-independent chaperone mediated protein folding
KR75_RS08530	COG1575	Belongs to the MenA family. Type 1 subfamily
KR75_RS08545	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
KR75_RS08550	COG1609	Transcriptional regulator
KR75_RS08555	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
KR75_RS08570	COG0626	cystathionine gamma-synthase activity
KR75_RS08575	COG0460	homoserine dehydrogenase
KR75_RS08575	COG0527	aspartate kinase activity
KR75_RS08585	COG0583	DNA-binding transcription factor activity
KR75_RS08595	COG0371	Dehydrogenase
KR75_RS08605	COG2207	Transcriptional regulator
KR75_RS08610	COG3443	Belongs to the bacterial solute-binding protein 9 family
KR75_RS08625	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
KR75_RS08640	COG0583	DNA-binding transcription factor activity
KR75_RS08715	COG3085	chromosome segregation
KR75_RS08730	COG3978	acetolactate synthase activity
KR75_RS08735	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
KR75_RS08745	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
KR75_RS08750	COG0583	DNA-binding transcription factor activity
KR75_RS08760	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
KR75_RS08765	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
KR75_RS08775	COG1811	Na channel or pump
KR75_RS08800	COG3118	belongs to the thioredoxin family
KR75_RS08805	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
KR75_RS08810	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
KR75_RS08820	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
KR75_RS08825	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
KR75_RS08830	COG1088	dTDP-glucose 4,6-dehydratase activity
KR75_RS08835	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
KR75_RS08840	COG0456	acetyltransferase
KR75_RS08845	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
KR75_RS08850	COG2244	polysaccharide biosynthetic process
KR75_RS08895	COG3071	HemY protein
KR75_RS08900	COG2959	enzyme of heme biosynthesis
KR75_RS08915	COG3072	Adenylate cyclase
KR75_RS08945	COG1011	Hydrolase
KR75_RS08950	COG0210	DNA helicase
KR75_RS08980	COG1280	lysine exporter protein (LysE YggA)
KR75_RS08990	COG1280	lysine exporter protein (LysE YggA)
KR75_RS08995	COG2267	carboxylic ester hydrolase activity
KR75_RS09000	COG0561	phosphatase activity
KR75_RS09005	COG0697	spore germination
KR75_RS09010	COG0583	DNA-binding transcription factor activity
KR75_RS09020	COG0412	Dienelactone hydrolase
KR75_RS09040	COG3165	ubiquinone biosynthetic process from chorismate
KR75_RS09060	COG0805	protein transport
KR75_RS09100	COG1739	Uncharacterized protein family UPF0029
KR75_RS09110	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
KR75_RS09140	COG0812	UDP-N-acetylmuramate dehydrogenase activity
KR75_RS09185	COG0250	Participates in transcription elongation, termination and antitermination
KR75_RS09220	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
KR75_RS09225	COG1447	Phosphotransferase system cellobiose-specific component IIA
KR75_RS09235	COG3706	GGDEF domain
KR75_RS09240	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
KR75_RS09250	COG2104	thiamine diphosphate biosynthetic process
KR75_RS09255	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
KR75_RS09270	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
KR75_RS09310	COG4191	Histidine kinase
KR75_RS09320	COG0151	Belongs to the GarS family
KR75_RS09350	COG0456	acetyltransferase
KR75_RS09360	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
KR75_RS09390	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
KR75_RS09455	COG0527	aspartate kinase activity
KR75_RS09465	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
KR75_RS09525	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
KR75_RS09535	COG0534	Mate efflux family protein
KR75_RS09540	COG3237	CsbD-like
KR75_RS09545	COG0735	belongs to the Fur family
KR75_RS09555	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KR75_RS09570	COG0305	Participates in initiation and elongation during chromosome replication
KR75_RS09575	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
KR75_RS09590	COG0432	Pfam Uncharacterised protein family UPF0047
KR75_RS09595	COG2315	Protein conserved in bacteria
KR75_RS09605	COG0629	single-stranded DNA binding
KR75_RS09610	COG0741	lytic transglycosylase activity
KR75_RS09615	COG4771	TonB-dependent receptor
KR75_RS09630	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
KR75_RS09640	COG0583	DNA-binding transcription factor activity
KR75_RS09650	COG0483	inositol monophosphate 1-phosphatase activity
KR75_RS09655	COG1609	Transcriptional regulator
KR75_RS09660	COG1234	tRNA 3'-trailer cleavage
KR75_RS09665	COG3842	ATPase activity
KR75_RS09690	COG4943	cyclic-guanylate-specific phosphodiesterase activity
KR75_RS09700	COG0789	Transcriptional regulator
KR75_RS09705	COG0625	glutathione transferase activity
KR75_RS09710	COG2252	PERMEase
KR75_RS09715	COG0025	NhaP-type Na H and K H
KR75_RS09720	COG0583	DNA-binding transcription factor activity
KR75_RS09725	COG1380	Effector of murein hydrolase LrgA
KR75_RS09730	COG1346	cytolysis
KR75_RS09735	COG3539	Fimbrial protein
KR75_RS09765	COG3162	membrane
KR75_RS09780	COG1301	dicarboxylic acid transport
KR75_RS09785	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
KR75_RS09790	COG3383	formate dehydrogenase (NAD+) activity
KR75_RS09795	COG3383	formate dehydrogenase (NAD+) activity
KR75_RS09825	COG1172	Belongs to the binding-protein-dependent transport system permease family
KR75_RS09830	COG1129	ABC transporter
KR75_RS09835	COG0784	Response regulator, receiver
KR75_RS09835	COG4191	Histidine kinase
KR75_RS09845	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
KR75_RS09855	COG3454	Phosphonate metabolism
KR75_RS09860	COG4778	phosphonate C-P lyase system protein PhnL
KR75_RS09865	COG4107	phosphonate C-P lyase system protein PhnK
KR75_RS09870	COG3627	carbon phosphorus lyase activity
KR75_RS09875	COG3626	phosphonate metabolism
KR75_RS09880	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
KR75_RS09885	COG3624	Phosphonate C-P lyase system protein PhnG
KR75_RS09890	COG2188	Transcriptional regulator
KR75_RS09895	COG2764	glyoxalase bleomycin resistance protein dioxygenase
KR75_RS09900	COG2824	Alkylphosphonate utilization operon protein PhnA
KR75_RS09910	COG2169	Transcriptional regulator
KR75_RS09915	COG1486	melibiose metabolic process
KR75_RS09945	COG0861	Integral membrane protein TerC family
KR75_RS09960	COG1215	transferase activity, transferring glycosyl groups
KR75_RS09965	COG0726	polysaccharide deacetylase
KR75_RS09965	COG1649	PFAM Uncharacterised BCR, COG1649
KR75_RS09970	COG0457	Tetratricopeptide repeat
KR75_RS09995	COG1309	transcriptional regulator
KR75_RS10010	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
KR75_RS10015	COG1027	Aspartate ammonia-lyase
KR75_RS10020	COG3030	protein affecting phage T7 exclusion by the F plasmid
KR75_RS10025	COG0531	amino acid
KR75_RS10090	COG1509	lysine 2,3-aminomutase activity
KR75_RS10110	COG2076	Multidrug Resistance protein
KR75_RS10130	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
KR75_RS10135	COG1053	succinate dehydrogenase
KR75_RS10150	COG1511	domain protein
KR75_RS10150	COG3264	Mechanosensitive ion channel
KR75_RS10170	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KR75_RS10190	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
KR75_RS10195	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
KR75_RS10195	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
KR75_RS10200	COG0802	atpase or kinase
KR75_RS10205	COG0860	N-Acetylmuramoyl-L-alanine amidase
KR75_RS10225	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
KR75_RS10230	COG0330	HflC and HflK could
KR75_RS10235	COG0330	HflC and HflK could
KR75_RS10245	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
KR75_RS10260	COG0557	exoribonuclease II activity
KR75_RS10265	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KR75_RS10270	COG1960	acyl-CoA dehydrogenase activity
KR75_RS10280	COG3650	response to hydrogen peroxide
KR75_RS10285	COG1073	alpha beta
KR75_RS10345	COG2965	DNA replication, synthesis of RNA primer
KR75_RS10350	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
KR75_RS10360	COG3061	Opacity-associated protein A
KR75_RS10365	COG0545	Peptidyl-prolyl cis-trans isomerase
KR75_RS10370	COG1113	amino acid transport
KR75_RS10380	COG0697	spore germination
KR75_RS10390	COG0702	epimerase
KR75_RS10395	COG1733	regulation of RNA biosynthetic process
KR75_RS10410	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
KR75_RS10435	COG1253	flavin adenine dinucleotide binding
KR75_RS10440	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
KR75_RS10445	COG1609	Transcriptional regulator
KR75_RS10450	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KR75_RS10455	COG1914	H( )-stimulated, divalent metal cation uptake system
KR75_RS10470	COG0729	surface antigen
KR75_RS10475	COG2911	Protein conserved in bacteria
KR75_RS10480	COG2105	PFAM AIG2 family protein
KR75_RS10495	COG1879	ABC-type sugar transport system periplasmic component
KR75_RS10500	COG1129	ABC transporter
KR75_RS10505	COG1172	Belongs to the binding-protein-dependent transport system permease family
KR75_RS10510	COG1172	Belongs to the binding-protein-dependent transport system permease family
KR75_RS10520	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
KR75_RS10540	COG0312	modulator of DNA gyrase
KR75_RS10575	COG3964	amidohydrolase
KR75_RS10590	COG2706	6-phosphogluconolactonase activity
KR75_RS10595	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
KR75_RS10595	COG3711	transcriptional antiterminator
KR75_RS10600	COG0602	queuosine metabolic process
KR75_RS10610	COG0366	Alpha amylase catalytic
KR75_RS10615	COG1263	PTS System
KR75_RS10615	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KR75_RS10645	COG2731	YhcH YjgK YiaL family protein
KR75_RS10670	COG0525	valine-tRNA ligase activity
KR75_RS10675	COG2927	DNA polymerase III (CHI subunit)
KR75_RS10685	COG0795	lipopolysaccharide-transporting ATPase activity
KR75_RS10690	COG0795	lipopolysaccharide-transporting ATPase activity
KR75_RS10695	COG0433	COG0433 Predicted ATPase
KR75_RS10710	COG3718	enzyme involved in inositol metabolism
KR75_RS10715	COG1737	Transcriptional regulator
KR75_RS10715	COG0837	glucose binding
KR75_RS10720	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KR75_RS10725	COG3962	Belongs to the TPP enzyme family
KR75_RS10735	COG1082	Xylose isomerase domain protein TIM barrel
KR75_RS10745	COG1653	transport
KR75_RS10750	COG3842	ATPase activity
KR75_RS10755	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
KR75_RS10760	COG0395	ABC-type sugar transport system, permease component
KR75_RS10765	COG1175	transmembrane transport
KR75_RS10770	COG1064	alcohol dehydrogenase
KR75_RS10775	COG0659	secondary active sulfate transmembrane transporter activity
KR75_RS10780	COG0288	reversible hydration of carbon dioxide
KR75_RS10845	COG0582	viral genome integration into host DNA
KR75_RS10915	COG3507	Belongs to the glycosyl hydrolase 43 family
KR75_RS10920	COG2211	Major facilitator Superfamily
KR75_RS10930	COG4580	involved in the transport of maltose and maltodextrins
KR75_RS10935	COG3272	Protein of unknown function (DUF1722)
KR75_RS10955	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
KR75_RS10970	COG0300	oxidoreductase activity
KR75_RS10975	COG3631	Ketosteroid isomerase-related protein
KR75_RS10980	COG0789	Transcriptional regulator
KR75_RS10985	COG3040	lipid binding
KR75_RS10995	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KR75_RS11000	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KR75_RS11005	COG5569	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KR75_RS11010	COG1538	Outer membrane efflux protein
KR75_RS11015	COG0745	RESPONSE REGULATOR receiver
KR75_RS11020	COG5002	protein histidine kinase activity
KR75_RS11025	COG2850	peptidyl-arginine hydroxylation
KR75_RS11055	COG0842	Transport permease protein
KR75_RS11060	COG0842	Transport permease protein
KR75_RS11060	COG1129	ABC transporter
KR75_RS11065	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KR75_RS11070	COG3706	GGDEF domain
KR75_RS11080	COG1879	ABC-type sugar transport system periplasmic component
KR75_RS11085	COG1129	ABC transporter
KR75_RS11090	COG1172	Belongs to the binding-protein-dependent transport system permease family
KR75_RS11100	COG2249	NAD(P)H dehydrogenase (quinone) activity
KR75_RS11105	COG0583	DNA-binding transcription factor activity
KR75_RS11115	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KR75_RS11125	COG1566	PFAM secretion protein HlyD family protein
KR75_RS11135	COG0583	DNA-binding transcription factor activity
KR75_RS11140	COG3366	ferrous iron transmembrane transporter activity
KR75_RS11145	COG0700	Nucleoside recognition
KR75_RS11150	COG1473	amidohydrolase
KR75_RS11160	COG1924	4 iron, 4 sulfur cluster binding
KR75_RS11165	COG1775	2-hydroxyglutaryl-CoA dehydratase, D-component
KR75_RS11180	COG2733	membrane
KR75_RS11190	COG2207	Transcriptional regulator
KR75_RS11190	COG1917	Cupin 2, conserved barrel domain protein
KR75_RS11195	COG5464	transposase or invertase
KR75_RS11200	COG1012	belongs to the aldehyde dehydrogenase family
KR75_RS11215	COG0523	cobalamin synthesis protein
KR75_RS11220	COG2879	small protein
KR75_RS11225	COG1966	Carbon starvation protein
KR75_RS11240	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
KR75_RS11245	COG2368	4-hydroxyphenylacetate
KR75_RS11265	COG3971	2-oxopent-4-enoate hydratase activity
KR75_RS11275	COG3384	dioxygenase
KR75_RS11280	COG1012	belongs to the aldehyde dehydrogenase family
KR75_RS11290	COG0179	Fumarylacetoacetate (FAA) hydrolase
KR75_RS11295	COG1846	Transcriptional regulator
KR75_RS11310	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KR75_RS11310	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
KR75_RS11325	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KR75_RS11330	COG1012	belongs to the aldehyde dehydrogenase family
KR75_RS11335	COG0531	amino acid
KR75_RS11350	COG1214	PFAM Peptidase M22, glycoprotease
KR75_RS11350	COG0456	acetyltransferase
KR75_RS11355	COG2271	Major facilitator Superfamily
KR75_RS11360	COG1802	Transcriptional regulator
KR75_RS11365	COG1063	alcohol dehydrogenase
KR75_RS11375	COG3933	PFAM sigma-54 factor interaction domain-containing protein
KR75_RS11375	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
KR75_RS11390	COG3715	PTS system
KR75_RS11395	COG3716	PTS system mannose fructose sorbose family IID component
KR75_RS11400	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
KR75_RS11425	COG1484	DNA-dependent DNA replication
KR75_RS11440	COG2966	Psort location CytoplasmicMembrane, score
KR75_RS11450	COG2169	Transcriptional regulator
KR75_RS11450	COG1917	Cupin 2, conserved barrel domain protein
KR75_RS11455	COG2197	response regulator
KR75_RS11460	COG2197	response regulator
KR75_RS11465	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
KR75_RS11470	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
KR75_RS11475	COG4114	ferric iron reductase
KR75_RS11480	COG3706	GGDEF domain
KR75_RS11510	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
KR75_RS11515	COG0456	acetyltransferase
KR75_RS11520	COG1011	Hydrolase
KR75_RS11530	COG2823	Periplasmic or secreted lipoprotein
KR75_RS11535	COG4667	esterase of the alpha-beta hydrolase superfamily
KR75_RS11540	COG0084	hydrolase, TatD family'
KR75_RS11570	COG3726	membrane protein affecting hemolysin expression
KR75_RS11575	COG0560	Phosphoserine phosphatase
KR75_RS11580	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
KR75_RS11590	COG0488	(ABC) transporter
KR75_RS11595	COG0741	lytic transglycosylase activity
KR75_RS11615	COG3708	Transcriptional regulator
KR75_RS11615	COG2207	Transcriptional regulator
KR75_RS11620	COG3045	CreA protein
KR75_RS11625	COG0745	RESPONSE REGULATOR receiver
KR75_RS11630	COG2205	protein histidine kinase activity
KR75_RS11635	COG4452	Inner membrane protein CreD
KR75_RS11640	COG0745	RESPONSE REGULATOR receiver
KR75_RS11645	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
KR75_RS11650	COG0527	aspartate kinase activity
KR75_RS11650	COG0460	homoserine dehydrogenase
KR75_RS11660	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
KR75_RS11675	COG1115	amino acid carrier protein
KR75_RS11680	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
KR75_RS11685	COG0521	Mo-molybdopterin cofactor biosynthetic process
KR75_RS11690	COG0477	Major facilitator Superfamily
KR75_RS11695	COG1584	GPR1 FUN34 yaaH family protein
KR75_RS11700	COG4735	regulation of single-species biofilm formation
KR75_RS11725	COG0583	DNA-binding transcription factor activity
KR75_RS11735	COG0196	riboflavin kinase activity
KR75_RS11750	COG1047	Peptidyl-prolyl cis-trans
KR75_RS11785	COG0505	Belongs to the CarA family
KR75_RS11800	COG2731	YhcH YjgK YiaL family protein
KR75_RS11805	COG3265	gluconokinase activity
KR75_RS11810	COG1028	Short-chain dehydrogenase reductase Sdr
KR75_RS11815	COG1609	Transcriptional regulator
KR75_RS11820	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KR75_RS11825	COG2271	Major facilitator Superfamily
KR75_RS11860	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
KR75_RS11870	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
KR75_RS11875	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
KR75_RS11890	COG3493	citrate carrier protein
KR75_RS11900	COG0564	pseudouridine synthase activity
KR75_RS11915	COG0417	DNA replication proofreading
KR75_RS11920	COG0235	Class ii aldolase
KR75_RS11940	COG0586	Pfam SNARE associated Golgi protein
KR75_RS11950	COG1178	ABC-type Fe3 transport system permease component
KR75_RS11965	COG2814	Major facilitator Superfamily
KR75_RS11970	COG2271	Major facilitator Superfamily
KR75_RS11975	COG0583	DNA-binding transcription factor activity
KR75_RS11985	COG0738	Major facilitator superfamily
KR75_RS11990	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
KR75_RS12025	COG0028	Belongs to the TPP enzyme family
KR75_RS12035	COG1609	Transcriptional regulator
KR75_RS12055	COG0768	penicillin binding
KR75_RS12065	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
KR75_RS12080	COG0772	Belongs to the SEDS family
KR75_RS12095	COG1181	Belongs to the D-alanine--D-alanine ligase family
KR75_RS12105	COG0849	cell division
KR75_RS12110	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
KR75_RS12130	COG0494	nUDIX hydrolase
KR75_RS12155	COG1459	type II secretion system
KR75_RS12160	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
KR75_RS12165	COG4969	Belongs to the N-Me-Phe pilin family
KR75_RS12175	COG3023	N-Acetylmuramoyl-L-alanine amidase
KR75_RS12180	COG3725	Membrane protein required for beta-lactamase induction
KR75_RS12185	COG3940	Belongs to the glycosyl hydrolase 43 family
KR75_RS12190	COG2211	Major facilitator Superfamily
KR75_RS12195	COG1113	amino acid transport
KR75_RS12200	COG2186	Transcriptional regulator
KR75_RS12205	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
KR75_RS12210	COG0508	dehydrogenase complex catalyzes the overall conversion of
KR75_RS12215	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KR75_RS12230	COG3064	Membrane
KR75_RS12255	COG0545	Peptidyl-prolyl cis-trans isomerase
KR75_RS12270	COG2132	Multicopper oxidase
KR75_RS12275	COG4993	Dehydrogenase
KR75_RS12285	COG0288	reversible hydration of carbon dioxide
KR75_RS12290	COG1131	(ABC) transporter
KR75_RS12295	COG0842	Transport permease protein
KR75_RS12300	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
KR75_RS12305	COG0726	polysaccharide deacetylase
KR75_RS12325	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
KR75_RS12330	COG0617	tRNA 3'-terminal CCA addition
KR75_RS12350	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
KR75_RS12355	COG1643	Atp-dependent helicase
KR75_RS12440	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KR75_RS12445	COG4774	siderophore transport
KR75_RS12450	COG1120	ATPase activity
KR75_RS12455	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KR75_RS12460	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KR75_RS12480	COG2860	membrane
KR75_RS12500	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KR75_RS12505	COG3835	regulator
KR75_RS12520	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
KR75_RS12525	COG0024	Methionine aminopeptidase
KR75_RS12560	COG0575	Belongs to the CDS family
KR75_RS12565	COG0750	zinc metalloprotease
KR75_RS12575	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
KR75_RS12615	COG1982	Orn Lys Arg decarboxylase major
KR75_RS12620	COG0346	lactoylglutathione lyase activity
KR75_RS12630	COG4568	rho-dependent transcription termination
KR75_RS12645	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
KR75_RS12650	COG3015	lipoprotein NlpE involved in copper resistance
KR75_RS12665	COG1720	tRNA m6t6A37 methyltransferase activity
KR75_RS12675	COG1464	Belongs to the NlpA lipoprotein family
KR75_RS12680	COG2011	ABC-type metal ion transport system permease component
KR75_RS12690	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
KR75_RS12725	COG0656	L-ascorbic acid biosynthetic process
KR75_RS12730	COG0583	DNA-binding transcription factor activity
KR75_RS12735	COG2814	Major facilitator Superfamily
KR75_RS12745	COG2226	methyltransferase
KR75_RS12750	COG1388	LysM domain
KR75_RS12750	COG0741	lytic transglycosylase activity
KR75_RS12760	COG2226	methyltransferase
KR75_RS12780	COG0583	DNA-binding transcription factor activity
KR75_RS12795	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
KR75_RS12800	COG1960	acyl-CoA dehydrogenase activity
KR75_RS12810	COG0121	glutamine amidotransferase
KR75_RS12815	COG3034	peptidoglycan biosynthetic process
KR75_RS12835	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
KR75_RS12840	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
KR75_RS12855	COG2991	Protein conserved in bacteria
KR75_RS12870	COG0454	-acetyltransferase
KR75_RS12875	COG2195	Cleaves the N-terminal amino acid of tripeptides
KR75_RS12895	COG1802	Transcriptional regulator
KR75_RS12900	COG1113	amino acid transport
KR75_RS12905	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
KR75_RS12910	COG1012	belongs to the aldehyde dehydrogenase family
KR75_RS12915	COG0579	oxidoreductase
KR75_RS12930	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
KR75_RS12935	COG0625	glutathione transferase activity
KR75_RS12945	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KR75_RS12950	COG0508	dehydrogenase complex catalyzes the overall conversion of
KR75_RS12955	COG0022	dehydrogenase e1 component
KR75_RS12960	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
KR75_RS12970	COG0519	Catalyzes the synthesis of GMP from XMP
KR75_RS12970	COG0518	GMP synthase (glutamine-hydrolyzing) activity
KR75_RS12980	COG2207	Transcriptional regulator
KR75_RS13000	COG1116	anion transmembrane transporter activity
KR75_RS13005	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KR75_RS13010	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KR75_RS13035	COG0791	NLP P60 protein
KR75_RS13050	COG3639	organic phosphonate transmembrane transporter activity
KR75_RS13060	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
KR75_RS13085	COG3188	usher protein
KR75_RS13100	COG0765	amino acid transport
KR75_RS13105	COG4597	amino acid ABC transporter
KR75_RS13110	COG1126	abc transporter atp-binding protein
KR75_RS13115	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KR75_RS13150	COG4302	ethanolamine ammonia-lyase activity
KR75_RS13155	COG4303	Ethanolamine ammonia lyase large subunit
KR75_RS13165	COG0833	amino acid
KR75_RS13170	COG2040	homocysteine
KR75_RS13175	COG4521	taurine ABC transporter
KR75_RS13180	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
KR75_RS13185	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KR75_RS13190	COG2175	clavaminate synthase activity
KR75_RS13205	COG0113	porphobilinogen synthase activity
KR75_RS13210	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
KR75_RS13215	COG1335	isochorismatase
KR75_RS13220	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
KR75_RS13240	COG1181	Belongs to the D-alanine--D-alanine ligase family
KR75_RS13260	COG1785	Belongs to the alkaline phosphatase family
KR75_RS13270	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KR75_RS13280	COG3416	Protein conserved in bacteria
KR75_RS13285	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
KR75_RS13295	COG4126	flavin adenine dinucleotide binding
KR75_RS13310	COG1940	carbohydrate kinase activity
KR75_RS13315	COG0419	ATPase involved in DNA repair
KR75_RS13320	COG0420	3'-5' exonuclease activity
KR75_RS13345	COG0366	Alpha amylase catalytic
KR75_RS13350	COG0583	DNA-binding transcription factor activity
KR75_RS13355	COG1335	isochorismatase
KR75_RS13365	COG1228	amidohydrolase
KR75_RS13375	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KR75_RS13390	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
KR75_RS13395	COG0450	alkyl hydroperoxide reductase
KR75_RS13415	COG1862	Preprotein translocase
KR75_RS13420	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
KR75_RS13425	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
KR75_RS13445	COG4238	major outer membrane lipoprotein
KR75_RS13455	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KR75_RS13455	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KR75_RS13470	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
KR75_RS13475	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
KR75_RS13480	COG0667	Aldo Keto reductase
KR75_RS13490	COG0142	geranyltranstransferase activity
KR75_RS13515	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
KR75_RS13525	COG2814	Major facilitator Superfamily
KR75_RS13530	COG0673	inositol 2-dehydrogenase activity
KR75_RS13545	COG1053	succinate dehydrogenase
KR75_RS13555	COG1053	succinate dehydrogenase
KR75_RS13560	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
KR75_RS13565	COG1414	Transcriptional regulator
KR75_RS13580	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
KR75_RS13585	COG1845	cytochrome c oxidase, subunit III
KR75_RS13590	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
KR75_RS13595	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
KR75_RS13600	COG2223	nitrite transmembrane transporter activity
KR75_RS13605	COG3056	Lipoprotein
KR75_RS13610	COG0271	Belongs to the BolA IbaG family
KR75_RS13630	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
KR75_RS13635	COG0776	regulation of translation
KR75_RS13640	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
KR75_RS13645	COG1555	photosystem II stabilization
KR75_RS13650	COG0824	Thioesterase
KR75_RS13660	COG4533	DNA binding
KR75_RS13675	COG1522	sequence-specific DNA binding
KR75_RS13680	COG1132	(ABC) transporter
KR75_RS13685	COG1132	(ABC) transporter
KR75_RS13690	COG0347	Belongs to the P(II) protein family
KR75_RS13695	COG0004	ammonium transporteR
KR75_RS13700	COG1946	Acyl-CoA thioesterase
KR75_RS13705	COG3126	Type III secretion system lipoprotein chaperone (YscW)
KR75_RS13710	COG3695	enzyme binding
KR75_RS13735	COG2364	Membrane
KR75_RS13750	COG4943	cyclic-guanylate-specific phosphodiesterase activity
KR75_RS13760	COG2182	Extracellular solute-binding protein
KR75_RS13765	COG1175	transmembrane transport
KR75_RS13770	COG3833	ABC-type maltose transport systems, permease component
KR75_RS13775	COG3867	Arabinogalactan endo-beta-1,4-galactanase
KR75_RS13780	COG1874	Beta-galactosidase
KR75_RS13825	COG0110	maltose O-acetyltransferase activity
KR75_RS13840	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KR75_RS13845	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KR75_RS13850	COG1309	transcriptional regulator
KR75_RS13855	COG3264	Mechanosensitive ion channel
KR75_RS13855	COG1196	nuclear chromosome segregation
KR75_RS13865	COG3923	Primosomal replication protein n
KR75_RS13870	COG2832	Protein of unknown function (DUF454)
KR75_RS13910	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KR75_RS13915	COG4651	solute:proton antiporter activity
KR75_RS13915	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
KR75_RS13920	COG2223	nitrite transmembrane transporter activity
KR75_RS13930	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
KR75_RS13935	COG3735	TraB family
KR75_RS13950	COG1585	Membrane protein implicated in regulation of membrane protease activity
KR75_RS13955	COG0330	HflC and HflK could
KR75_RS13960	COG4619	ABC transporter
KR75_RS13965	COG0390	transport system, permease component
KR75_RS13970	COG3118	belongs to the thioredoxin family
KR75_RS13975	COG0300	oxidoreductase activity
KR75_RS13980	COG2755	lipolytic protein G-D-S-L family
KR75_RS13985	COG4181	ATPase activity
KR75_RS13990	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
KR75_RS14005	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
KR75_RS14010	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
KR75_RS14025	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
KR75_RS14035	COG2501	S4 domain
KR75_RS14080	COG3539	Fimbrial protein
KR75_RS14085	COG3121	Chaperone
KR75_RS14090	COG3188	usher protein
KR75_RS14105	COG1560	Kdo2-lipid A biosynthetic process
KR75_RS14115	COG3710	Transcriptional regulator
KR75_RS14120	COG0531	amino acid
KR75_RS14125	COG1982	Orn Lys Arg decarboxylase major
KR75_RS14130	COG3104	oligopeptide transport
KR75_RS14165	COG0673	inositol 2-dehydrogenase activity
KR75_RS14180	COG1129	ABC transporter
KR75_RS14185	COG4211	Belongs to the binding-protein-dependent transport system permease family
KR75_RS14230	COG1566	PFAM secretion protein HlyD family protein
KR75_RS14235	COG1120	ATPase activity
KR75_RS14240	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KR75_RS14265	COG1473	amidohydrolase
KR75_RS14270	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KR75_RS14275	COG0667	Aldo Keto reductase
KR75_RS14305	COG4680	protein conserved in bacteria
KR75_RS14320	COG0531	amino acid
KR75_RS14330	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KR75_RS14335	COG1012	belongs to the aldehyde dehydrogenase family
KR75_RS14350	COG1113	amino acid transport
KR75_RS14355	COG2211	Major facilitator Superfamily
KR75_RS14365	COG0673	inositol 2-dehydrogenase activity
KR75_RS14375	COG1609	Transcriptional regulator
KR75_RS14380	COG0668	transmembrane transport
KR75_RS14385	COG0477	Major facilitator Superfamily
KR75_RS14400	COG3933	PFAM sigma-54 factor interaction domain-containing protein
KR75_RS14400	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
KR75_RS14405	COG2222	sugar isomerase
KR75_RS14410	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
KR75_RS14415	COG3716	PTS system mannose fructose sorbose family IID component
KR75_RS14425	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KR75_RS14435	COG0778	Nitroreductase
KR75_RS14440	COG2315	Protein conserved in bacteria
KR75_RS14480	COG3698	Phosphodiester glycosidase
KR75_RS14490	COG4166	transmembrane transport
KR75_RS14500	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KR75_RS14505	COG4608	Belongs to the ABC transporter superfamily
KR75_RS14520	COG0697	spore germination
KR75_RS14535	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
KR75_RS14540	COG0765	amino acid transport
KR75_RS14545	COG4215	(ABC) transporter
KR75_RS14555	COG4221	oxidoreductase activity
KR75_RS14560	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
KR75_RS14565	COG4608	Belongs to the ABC transporter superfamily
KR75_RS14570	COG0444	Belongs to the ABC transporter superfamily
KR75_RS14575	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KR75_RS14580	COG0601	transmembrane transport
KR75_RS14585	COG0747	negative chemotaxis
KR75_RS14630	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
KR75_RS14640	COG0668	transmembrane transport
KR75_RS14645	COG0583	DNA-binding transcription factor activity
KR75_RS14655	COG1028	Short-chain dehydrogenase reductase Sdr
KR75_RS14665	COG1172	Belongs to the binding-protein-dependent transport system permease family
KR75_RS14670	COG1129	ABC transporter
KR75_RS14680	COG1879	ABC-type sugar transport system periplasmic component
KR75_RS14685	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
KR75_RS14690	COG2390	Transcriptional regulator
KR75_RS14695	COG3959	Transketolase, thiamine diphosphate binding domain
KR75_RS14700	COG3958	Transketolase
KR75_RS14705	COG2977	Belongs to the P-Pant transferase superfamily
KR75_RS14710	COG4771	TonB-dependent receptor
KR75_RS14715	COG2382	esterase
KR75_RS14720	COG3251	PFAM MbtH domain protein
KR75_RS14725	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KR75_RS14725	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
KR75_RS14730	COG1120	ATPase activity
KR75_RS14735	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KR75_RS14740	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KR75_RS14750	COG4592	Periplasmic binding protein
KR75_RS14755	COG1169	isochorismate synthase
KR75_RS14760	COG1021	2,3-dihydroxybenzoate-AMP ligase
KR75_RS14765	COG3433	isochorismatase activity
KR75_RS14765	COG1535	isochorismatase
KR75_RS14770	COG1028	Short-chain dehydrogenase reductase Sdr
KR75_RS14785	COG1966	Carbon starvation protein
KR75_RS14790	COG2879	small protein
KR75_RS14810	COG0371	Dehydrogenase
KR75_RS14815	COG1129	ABC transporter
KR75_RS14820	COG1172	Belongs to the binding-protein-dependent transport system permease family
KR75_RS14850	COG2271	Major facilitator Superfamily
KR75_RS14855	COG0483	inositol monophosphate 1-phosphatase activity
KR75_RS14865	COG0402	S-adenosylhomocysteine deaminase activity
KR75_RS14875	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
KR75_RS14890	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
KR75_RS14900	COG1172	Belongs to the binding-protein-dependent transport system permease family
KR75_RS14905	COG1172	Belongs to the binding-protein-dependent transport system permease family
KR75_RS14910	COG1129	ABC transporter
KR75_RS14935	COG0436	Aminotransferase
KR75_RS14940	COG1475	DNA binding
KR75_RS14945	COG3969	phosphoadenosine phosphosulfate
KR75_RS14950	COG0583	DNA-binding transcription factor activity
KR75_RS14955	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
KR75_RS14975	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
KR75_RS14980	COG3719	Belongs to the RNase T2 family
KR75_RS14985	COG3069	C4-dicarboxylate transmembrane transporter activity
KR75_RS15005	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
KR75_RS15010	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
KR75_RS15020	COG0583	DNA-binding transcription factor activity
KR75_RS15035	COG1686	Belongs to the peptidase S11 family
KR75_RS15040	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
KR75_RS15045	COG0772	Belongs to the SEDS family
KR75_RS15050	COG0768	penicillin binding
KR75_RS15060	COG0799	negative regulation of ribosome biogenesis
KR75_RS15075	COG1466	dna polymerase III delta subunit
KR75_RS15090	COG2888	peptidyl-tyrosine sulfation
KR75_RS15105	COG1126	abc transporter atp-binding protein
KR75_RS15110	COG0765	amino acid transport
KR75_RS15115	COG0765	amino acid transport
KR75_RS15140	COG1702	phosphate starvation-inducible protein PhoH
KR75_RS15150	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KR75_RS15190	COG0367	asparagine synthase
KR75_RS15195	COG0647	UMP catabolic process
KR75_RS15200	COG1940	carbohydrate kinase activity
KR75_RS15200	COG1846	Transcriptional regulator
KR75_RS15205	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
KR75_RS15245	COG1053	succinate dehydrogenase
KR75_RS15250	COG0583	DNA-binding transcription factor activity
KR75_RS15255	COG0735	belongs to the Fur family
KR75_RS15270	COG0596	Alpha beta hydrolase
KR75_RS15280	COG0033	Phosphoglucomutase
KR75_RS15290	COG0745	RESPONSE REGULATOR receiver
KR75_RS15295	COG2205	protein histidine kinase activity
KR75_RS15335	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
KR75_RS15340	COG1984	allophanate hydrolase subunit 2
KR75_RS15365	COG2009	succinate dehydrogenase
KR75_RS15370	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
KR75_RS15375	COG1053	succinate dehydrogenase
KR75_RS15380	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
KR75_RS15385	COG0567	Dehydrogenase, E1 component
KR75_RS15390	COG0508	dehydrogenase complex catalyzes the overall conversion of
KR75_RS15400	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
KR75_RS15405	COG1271	oxidase subunit
KR75_RS15410	COG1294	oxidase, subunit
KR75_RS15415	COG3790	cyd operon protein YbgE
KR75_RS15420	COG0824	Thioesterase
KR75_RS15425	COG0811	peptide transport
KR75_RS15430	COG0848	biopolymer transport protein
KR75_RS15435	COG3064	Membrane
KR75_RS15435	COG3064	Membrane
KR75_RS15445	COG2885	chlorophyll binding
KR75_RS15450	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
KR75_RS15490	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
KR75_RS15495	COG3201	nicotinamide mononucleotide transporter
KR75_RS15500	COG1230	cation diffusion facilitator family transporter
KR75_RS15510	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
KR75_RS15520	COG2017	converts alpha-aldose to the beta-anomer
KR75_RS15530	COG1085	galactose-1-phosphate uridylyltransferase
KR75_RS15540	COG1119	ATPase activity
KR75_RS15545	COG3585	molybdate ion transport
KR75_RS15545	COG2005	Transcriptional regulator
KR75_RS15555	COG0725	ABC transporter, periplasmic molybdate-binding protein
KR75_RS15560	COG4149	molybdate abc transporter
KR75_RS15570	COG0561	phosphatase activity
KR75_RS15595	COG2200	EAL domain
KR75_RS15600	COG0789	Transcriptional regulator
KR75_RS15635	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KR75_RS15640	COG0589	response to stress
KR75_RS15650	COG4677	pectinesterase activity
KR75_RS15685	COG1881	PFAM PEBP family protein
KR75_RS15690	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
KR75_RS15705	COG2226	methyltransferase
KR75_RS15750	COG0521	Mo-molybdopterin cofactor biosynthetic process
KR75_RS15760	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
KR75_RS15765	COG0314	molybdopterin synthase activity
KR75_RS15770	COG0670	Belongs to the BI1 family
KR75_RS15775	COG0392	lysyltransferase activity
KR75_RS15780	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KR75_RS15785	COG3568	Endonuclease Exonuclease Phosphatase
KR75_RS15795	COG0842	Transport permease protein
KR75_RS15800	COG0842	Transport permease protein
KR75_RS15805	COG1131	(ABC) transporter
KR75_RS15810	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KR75_RS15815	COG1309	transcriptional regulator
KR75_RS15820	COG0583	DNA-binding transcription factor activity
KR75_RS15825	COG2271	Major facilitator Superfamily
KR75_RS15830	COG1028	Short-chain dehydrogenase reductase Sdr
KR75_RS15835	COG3959	Transketolase, thiamine diphosphate binding domain
KR75_RS15840	COG3958	Transketolase
KR75_RS15845	COG0513	Belongs to the DEAD box helicase family
KR75_RS15850	COG1199	ATP-dependent helicase activity
KR75_RS15855	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
KR75_RS15865	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
KR75_RS15875	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
KR75_RS15885	COG0668	transmembrane transport
KR75_RS15890	COG1126	abc transporter atp-binding protein
KR75_RS15895	COG0765	amino acid transport
KR75_RS15900	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KR75_RS15915	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
KR75_RS15920	COG2194	sulfuric ester hydrolase activity
KR75_RS15935	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
KR75_RS15940	COG0667	Aldo Keto reductase
KR75_RS15945	COG2723	6-phospho-beta-galactosidase activity
KR75_RS15950	COG2188	Transcriptional regulator
KR75_RS15955	COG1376	ErfK ybiS ycfS ynhG family protein
KR75_RS15965	COG0488	(ABC) transporter
KR75_RS15975	COG2271	Major facilitator Superfamily
KR75_RS15980	COG1609	Transcriptional regulator
KR75_RS15990	COG0561	phosphatase activity
KR75_RS15995	COG1882	Formate acetyltransferase
KR75_RS16000	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
KR75_RS16005	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
KR75_RS16010	COG0303	'Molybdopterin
KR75_RS16015	COG1446	asparaginase
KR75_RS16025	COG0747	negative chemotaxis
KR75_RS16050	COG2223	nitrite transmembrane transporter activity
KR75_RS16060	COG2133	pyrroloquinoline quinone binding
KR75_RS16065	COG0625	glutathione transferase activity
KR75_RS16070	COG1686	Belongs to the peptidase S11 family
KR75_RS16075	COG1349	DNA-binding transcription factor activity
KR75_RS16080	COG0671	phosphoesterase, PA-phosphatase related
KR75_RS16085	COG2814	Major facilitator Superfamily
KR75_RS16090	COG0561	phosphatase activity
KR75_RS16095	COG0738	Major facilitator superfamily
KR75_RS16100	COG3226	Transcriptional regulator
KR75_RS16105	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
KR75_RS16160	COG4695	Portal protein
KR75_RS16305	COG0778	Nitroreductase
KR75_RS16320	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
KR75_RS16325	COG3842	ATPase activity
KR75_RS16330	COG1176	ABC-type spermidine putrescine transport system, permease component I
KR75_RS16335	COG1177	transmembrane transport
KR75_RS16350	COG0745	RESPONSE REGULATOR receiver
KR75_RS16355	COG5002	protein histidine kinase activity
KR75_RS16360	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KR75_RS16365	COG4160	amino acid transport
KR75_RS16370	COG4215	(ABC) transporter
KR75_RS16375	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KR75_RS16380	COG1126	abc transporter atp-binding protein
KR75_RS16395	COG3706	GGDEF domain
KR75_RS16395	COG4251	negative regulation of phosphorylation
KR75_RS16395	COG5001	Diguanylate cyclase
KR75_RS16395	COG2203	Gaf domain
KR75_RS16400	COG3023	N-Acetylmuramoyl-L-alanine amidase
KR75_RS16405	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KR75_RS16410	COG0702	epimerase
KR75_RS16415	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
KR75_RS16420	COG0028	Belongs to the TPP enzyme family
KR75_RS16430	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
KR75_RS16440	COG2431	L-lysine efflux transmembrane transporter activity
KR75_RS16450	COG3593	DNA synthesis involved in DNA repair
KR75_RS16455	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KR75_RS16465	COG1278	Cold shock
KR75_RS16475	COG0542	response to heat
KR75_RS16490	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
KR75_RS16495	COG4988	ABC transporter
KR75_RS16500	COG0492	ferredoxin-NADP+ reductase activity
KR75_RS16520	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
KR75_RS16530	COG0243	molybdopterin cofactor binding
KR75_RS16535	COG0437	4 iron, 4 sulfur cluster binding
KR75_RS16540	COG3302	dmso reductase anchor subunit
KR75_RS16545	COG0477	Major facilitator Superfamily
KR75_RS16550	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
KR75_RS16555	COG1882	Formate acetyltransferase
KR75_RS16560	COG2116	formate transmembrane transporter activity
KR75_RS16565	COG1944	ATP diphosphatase activity
KR75_RS16570	COG2323	membrane
KR75_RS16590	COG0539	negative regulation of cytoplasmic translation
KR75_RS16600	COG0658	competence protein
KR75_RS16600	COG2333	competence protein COMEC
KR75_RS16615	COG3214	Protein conserved in bacteria
KR75_RS16630	COG3173	Aminoglycoside phosphotransferase
KR75_RS16635	COG1434	Gram-negative-bacterium-type cell wall biogenesis
KR75_RS16640	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
KR75_RS16650	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
KR75_RS16660	COG2989	Protein conserved in bacteria
KR75_RS16665	COG3108	Peptidase M15
KR75_RS16670	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KR75_RS16675	COG1448	Aminotransferase
KR75_RS16680	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
KR75_RS16690	COG1522	sequence-specific DNA binding
KR75_RS16700	COG0814	amino acid
KR75_RS16715	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
KR75_RS16720	COG0308	aminopeptidase N
KR75_RS16730	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KR75_RS16735	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KR75_RS16740	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KR75_RS16745	COG0431	NADPH-dependent FMN reductase
KR75_RS16760	COG3217	Mosc domain protein beta barrel domain protein
KR75_RS16760	COG0633	Ferredoxin
KR75_RS16770	COG0488	(ABC) transporter
KR75_RS16775	COG2995	paraquat-inducible protein a
KR75_RS16780	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
KR75_RS16780	COG3008	intermembrane lipid transfer
KR75_RS16785	COG3009	Protein conserved in bacteria
KR75_RS16795	COG1067	ATP-dependent peptidase activity
KR75_RS16815	COG3070	regulator of competence-specific genes
KR75_RS16820	COG1289	transmembrane transporter activity
KR75_RS16825	COG3304	Inner membrane component domain
KR75_RS16830	COG0210	DNA helicase
KR75_RS16840	COG1832	CoA-binding protein
KR75_RS16855	COG1881	PFAM PEBP family protein
KR75_RS16860	COG2207	Transcriptional regulator
KR75_RS16875	COG0670	Belongs to the BI1 family
KR75_RS16890	COG0058	SHG alpha-glucan phosphorylase activity
KR75_RS16900	COG2200	EAL domain
KR75_RS16920	COG3706	GGDEF domain
KR75_RS16925	COG2207	Transcriptional regulator
KR75_RS16935	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KR75_RS16940	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
KR75_RS16945	COG1882	Formate acetyltransferase
KR75_RS16950	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KR75_RS16955	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KR75_RS16965	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
KR75_RS16970	COG1012	belongs to the aldehyde dehydrogenase family
KR75_RS16975	COG4638	Rieske (2fe-2S)
KR75_RS16980	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
KR75_RS16985	COG0473	3-isopropylmalate dehydrogenase activity
KR75_RS16990	COG0583	DNA-binding transcription factor activity
KR75_RS16995	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KR75_RS17000	COG1012	belongs to the aldehyde dehydrogenase family
KR75_RS17005	COG1917	Cupin 2, conserved barrel domain protein
KR75_RS17005	COG1396	sequence-specific DNA binding
KR75_RS17010	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
KR75_RS17015	COG0174	glutamine synthetase
KR75_RS17020	COG0531	amino acid
KR75_RS17030	COG1028	Short-chain dehydrogenase reductase Sdr
KR75_RS17065	COG2233	PERMEase
KR75_RS17100	COG1309	transcriptional regulator
KR75_RS17115	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KR75_RS17125	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KR75_RS17145	COG1702	phosphate starvation-inducible protein PhoH
KR75_RS17160	COG1335	isochorismatase
KR75_RS17170	COG0583	DNA-binding transcription factor activity
KR75_RS17175	COG1309	transcriptional regulator
KR75_RS17200	COG3381	protein complex oligomerization
KR75_RS17235	COG5645	(Lipo)protein
KR75_RS17250	COG1560	Kdo2-lipid A biosynthetic process
KR75_RS17290	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KR75_RS17310	COG2814	Major facilitator Superfamily
KR75_RS17315	COG0583	DNA-binding transcription factor activity
KR75_RS17320	COG1530	ribonuclease E activity
KR75_RS17330	COG0424	maF-like protein
KR75_RS17335	COG1399	metal-binding, possibly nucleic acid-binding protein
KR75_RS17355	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
KR75_RS17370	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
KR75_RS17375	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
KR75_RS17380	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
KR75_RS17390	COG0470	DNA polymerase III
KR75_RS17395	COG0084	hydrolase, TatD family'
KR75_RS17405	COG0537	adenosine 5'-monophosphoramidase activity
KR75_RS17410	COG5633	Lipoprotein
KR75_RS17435	COG1252	NADH dehydrogenase
KR75_RS17440	COG3134	Outer membrane lipoprotein
KR75_RS17450	COG1309	transcriptional regulator
KR75_RS17460	COG1388	LysM domain
KR75_RS17460	COG1376	ErfK ybiS ycfS ynhG family protein
KR75_RS17465	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
KR75_RS17470	COG4591	ABC-type transport system involved in lipoprotein release permease component
KR75_RS17480	COG4591	ABC-type transport system involved in lipoprotein release permease component
KR75_RS17490	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
KR75_RS17500	COG0318	PFAM AMP-dependent synthetase and ligase
KR75_RS17515	COG1177	transmembrane transport
KR75_RS17535	COG2850	peptidyl-arginine hydroxylation
KR75_RS17540	COG2205	protein histidine kinase activity
KR75_RS17560	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
KR75_RS17580	COG1187	pseudouridine synthase activity
KR75_RS17585	COG0538	isocitrate dehydrogenase activity
KR75_RS17590	COG0582	viral genome integration into host DNA
KR75_RS17600	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
KR75_RS17625	COG1396	sequence-specific DNA binding
KR75_RS17670	COG1403	HNH endonuclease
KR75_RS17685	COG3772	lysozyme
KR75_RS17760	COG3706	GGDEF domain
KR75_RS17765	COG4943	cyclic-guanylate-specific phosphodiesterase activity
KR75_RS17780	COG0640	Transcriptional regulator
KR75_RS17810	COG3813	Protein conserved in bacteria
KR75_RS17815	COG1063	alcohol dehydrogenase
KR75_RS17820	COG3729	General stress protein
KR75_RS17825	COG3685	Protein conserved in bacteria
KR75_RS17830	COG3685	Protein conserved in bacteria
KR75_RS17835	COG3546	catalase activity
KR75_RS17840	COG1271	oxidase subunit
KR75_RS17845	COG1294	oxidase, subunit
KR75_RS17850	COG1566	PFAM secretion protein HlyD family protein
KR75_RS17865	COG2207	Transcriptional regulator
KR75_RS17895	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
KR75_RS17900	COG0583	DNA-binding transcription factor activity
KR75_RS17905	COG3706	GGDEF domain
KR75_RS17910	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
KR75_RS17920	COG1560	Kdo2-lipid A biosynthetic process
KR75_RS17930	COG3182	Iron-regulated membrane protein
KR75_RS17940	COG2199	diguanylate cyclase activity
KR75_RS17940	COG2203	Gaf domain
KR75_RS17945	COG3042	response to heat
KR75_RS17950	COG3189	MarR family transcriptional regulator
KR75_RS17955	COG1683	Conserved Protein
KR75_RS17960	COG0504	CTP synthase activity
KR75_RS17965	COG2807	transmembrane transport
KR75_RS17970	COG2207	Transcriptional regulator
KR75_RS17980	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
KR75_RS17985	COG0859	PFAM glycosyl transferase family 9
KR75_RS18005	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
KR75_RS18020	COG0436	Aminotransferase
KR75_RS18025	COG0504	CTP synthase activity
KR75_RS18030	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KR75_RS18035	COG0006	proline dipeptidase activity
KR75_RS18040	COG4948	Mandelate Racemase Muconate Lactonizing
KR75_RS18045	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KR75_RS18050	COG1126	abc transporter atp-binding protein
KR75_RS18055	COG0765	amino acid transport
KR75_RS18060	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KR75_RS18095	COG1283	sodium-dependent phosphate transmembrane transporter activity
KR75_RS18110	COG0583	DNA-binding transcription factor activity
KR75_RS18115	COG1028	Short-chain dehydrogenase reductase Sdr
KR75_RS18125	COG1902	pentaerythritol trinitrate reductase activity
KR75_RS18130	COG0583	DNA-binding transcription factor activity
KR75_RS18135	COG0300	oxidoreductase activity
KR75_RS18150	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
KR75_RS18160	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KR75_RS18165	COG0765	amino acid transport
KR75_RS18170	COG1126	abc transporter atp-binding protein
KR75_RS18205	COG0386	Belongs to the glutathione peroxidase family
KR75_RS18220	COG2766	serine protein kinase
KR75_RS18225	COG3713	MltA-interacting MipA family protein
KR75_RS18230	COG0656	L-ascorbic acid biosynthetic process
KR75_RS18250	COG3139	Protein of unknown function (DUF1315)
KR75_RS18265	COG1335	isochorismatase
KR75_RS18270	COG0252	asparaginase activity
KR75_RS18275	COG0616	signal peptide processing
KR75_RS18280	COG0778	Nitroreductase
KR75_RS18290	COG0709	Synthesizes selenophosphate from selenide and ATP
KR75_RS18295	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KR75_RS18300	COG1028	Short-chain dehydrogenase reductase Sdr
KR75_RS18300	COG3321	synthase
KR75_RS18300	COG0604	alcohol dehydrogenase
KR75_RS18305	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
KR75_RS18310	COG0494	nUDIX hydrolase
KR75_RS18315	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
KR75_RS18320	COG2897	thiosulfate sulfurtransferase activity
KR75_RS18325	COG4136	ATPase activity
KR75_RS18330	COG4135	transport system, permease component
KR75_RS18335	COG4134	Bacterial extracellular solute-binding protein
KR75_RS18340	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
KR75_RS18345	COG0398	Pfam SNARE associated Golgi protein
KR75_RS18350	COG0398	Pfam SNARE associated Golgi protein
KR75_RS18355	COG0708	Exodeoxyribonuclease III
KR75_RS18365	COG3138	arginine N-succinyltransferase
KR75_RS18375	COG3724	N-succinylarginine dihydrolase activity
KR75_RS18385	COG3678	ATP-independent chaperone mediated protein folding
KR75_RS18390	COG0322	excinuclease ABC activity
KR75_RS18400	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
KR75_RS18405	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
KR75_RS18410	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
KR75_RS18415	COG1447	Phosphotransferase system cellobiose-specific component IIA
KR75_RS18420	COG1917	Cupin 2, conserved barrel domain protein
KR75_RS18420	COG2169	Transcriptional regulator
KR75_RS18425	COG1486	melibiose metabolic process
KR75_RS18435	COG0753	catalase activity
KR75_RS18445	COG1823	symporter activity
KR75_RS18450	COG1988	membrane-bound metal-dependent
KR75_RS18455	COG1028	Short-chain dehydrogenase reductase Sdr
KR75_RS18460	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
KR75_RS18490	COG0727	PFAM Uncharacterised protein family (UPF0153)
KR75_RS18495	COG3047	cAMP biosynthetic process
KR75_RS18505	COG4774	siderophore transport
KR75_RS18550	COG0134	indole-3-glycerol-phosphate synthase activity
KR75_RS18550	COG0135	phosphoribosylanthranilate isomerase activity
KR75_RS18555	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
KR75_RS18555	COG0512	Glutamine amidotransferase of anthranilate synthase
KR75_RS18560	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
KR75_RS18570	COG0009	L-threonylcarbamoyladenylate synthase
KR75_RS18585	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
KR75_RS18590	COG1028	Short-chain dehydrogenase reductase Sdr
KR75_RS18600	COG0616	signal peptide processing
KR75_RS18620	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
KR75_RS18630	COG0671	phosphoesterase, PA-phosphatase related
KR75_RS18635	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
KR75_RS18640	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
KR75_RS18650	COG0023	Translation Initiation Factor
KR75_RS18660	COG1349	DNA-binding transcription factor activity
KR75_RS18675	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
KR75_RS18675	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
KR75_RS18680	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
KR75_RS18710	COG2986	histidine ammonia-lyase
KR75_RS18725	COG4171	peptide transport system, permease
KR75_RS18740	COG0702	epimerase
KR75_RS18755	COG1473	amidohydrolase
KR75_RS18765	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
KR75_RS18770	COG1842	Phage shock protein A
KR75_RS18780	COG1983	PspC domain protein
KR75_RS18790	COG3106	COG3106 Predicted ATPase
KR75_RS18805	COG3180	Ammonia monooxygenase
KR75_RS18810	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
KR75_RS18815	COG4948	Mandelate Racemase Muconate Lactonizing
KR75_RS18820	COG2866	Carboxypeptidase
KR75_RS18825	COG4166	transmembrane transport
KR75_RS18835	COG0765	amino acid transport
KR75_RS18845	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KR75_RS18850	COG0583	DNA-binding transcription factor activity
KR75_RS18855	COG0583	DNA-binding transcription factor activity
KR75_RS18860	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KR75_RS18900	COG0656	L-ascorbic acid biosynthetic process
KR75_RS18905	COG3250	beta-galactosidase activity
KR75_RS18965	COG0583	DNA-binding transcription factor activity
KR75_RS18970	COG1028	Short-chain dehydrogenase reductase Sdr
KR75_RS18975	COG0693	protein deglycase activity
KR75_RS19000	COG2885	chlorophyll binding
KR75_RS19060	COG1028	Short-chain dehydrogenase reductase Sdr
KR75_RS19065	COG1309	transcriptional regulator
KR75_RS19070	COG1028	Short-chain dehydrogenase reductase Sdr
KR75_RS19090	COG0583	DNA-binding transcription factor activity
KR75_RS19115	COG0604	alcohol dehydrogenase
KR75_RS19120	COG0436	Aminotransferase
KR75_RS19125	COG1464	Belongs to the NlpA lipoprotein family
KR75_RS19135	COG2011	ABC-type metal ion transport system permease component
KR75_RS19140	COG1448	Aminotransferase
KR75_RS19150	COG1522	sequence-specific DNA binding
KR75_RS19155	COG1113	amino acid transport
KR75_RS19170	COG0673	inositol 2-dehydrogenase activity
KR75_RS19175	COG1349	DNA-binding transcription factor activity
KR75_RS19185	COG0513	Belongs to the DEAD box helicase family
KR75_RS19195	COG0589	response to stress
KR75_RS19205	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
KR75_RS19210	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
KR75_RS19210	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
KR75_RS19210	COG1013	pyruvate-flavodoxin oxidoreductase activity
KR75_RS19210	COG0674	pyruvate-flavodoxin oxidoreductase activity
KR75_RS19215	COG3042	response to heat
KR75_RS19220	COG3187	Heat shock protein
KR75_RS19225	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KR75_RS19230	COG0586	Pfam SNARE associated Golgi protein
KR75_RS19235	COG2911	Protein conserved in bacteria
KR75_RS19245	COG3784	Protein of unknown function (DUF1318)
KR75_RS19250	COG2207	Transcriptional regulator
KR75_RS19255	COG1012	belongs to the aldehyde dehydrogenase family
KR75_RS19270	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KR75_RS19280	COG1126	abc transporter atp-binding protein
KR75_RS19285	COG0583	DNA-binding transcription factor activity
KR75_RS19290	COG2072	flavoprotein involved in K transport
KR75_RS19305	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KR75_RS19325	COG1012	belongs to the aldehyde dehydrogenase family
KR75_RS19325	COG2030	dehydratase
KR75_RS19330	COG3396	Phenylacetate-CoA oxygenase
KR75_RS19335	COG3460	Phenylacetate-CoA oxygenase
KR75_RS19340	COG3396	Phenylacetate-CoA oxygenase
KR75_RS19345	COG2151	metal-sulfur cluster biosynthetic enzyme
KR75_RS19350	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
KR75_RS19355	COG1024	Enoyl-CoA hydratase
KR75_RS19360	COG1024	Enoyl-CoA hydratase
KR75_RS19365	COG1250	3-hydroxyacyl-CoA dehydrogenase
KR75_RS19370	COG2050	protein possibly involved in aromatic compounds catabolism
KR75_RS19375	COG0183	Belongs to the thiolase family
KR75_RS19380	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
KR75_RS19385	COG3327	negative regulation of DNA-templated transcription, initiation
KR75_RS19390	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
KR75_RS19400	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system
KR75_RS19410	COG1643	Atp-dependent helicase
KR75_RS19420	COG4122	O-methyltransferase activity
KR75_RS19445	COG0583	DNA-binding transcription factor activity
KR75_RS19450	COG0667	Aldo Keto reductase
KR75_RS19455	COG2814	Major facilitator Superfamily
KR75_RS19460	COG0667	Aldo Keto reductase
KR75_RS19470	COG0183	Belongs to the thiolase family
KR75_RS19485	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
KR75_RS19490	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
KR75_RS19495	COG3138	arginine N-succinyltransferase
KR75_RS19500	COG1012	belongs to the aldehyde dehydrogenase family
KR75_RS19505	COG3724	N-succinylarginine dihydrolase activity
KR75_RS19510	COG2988	succinylglutamate desuccinylase activity
KR75_RS19515	COG1113	amino acid transport
KR75_RS19520	COG0477	Major facilitator Superfamily
KR75_RS19525	COG1434	Gram-negative-bacterium-type cell wall biogenesis
KR75_RS19530	COG1012	belongs to the aldehyde dehydrogenase family
KR75_RS19535	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
KR75_RS19545	COG5562	phage envelope protein
KR75_RS19550	COG0425	Belongs to the sulfur carrier protein TusA family
KR75_RS19580	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
KR75_RS19585	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KR75_RS19585	COG1263	PTS System
KR75_RS19590	COG1609	Transcriptional regulator
KR75_RS19595	COG5339	Protein conserved in bacteria
KR75_RS19600	COG1482	cell wall glycoprotein biosynthetic process
KR75_RS19605	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
KR75_RS19605	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
KR75_RS19610	COG0114	fumarate hydratase activity
KR75_RS19620	COG2205	protein histidine kinase activity
KR75_RS19625	COG1028	Short-chain dehydrogenase reductase Sdr
KR75_RS19635	COG0745	RESPONSE REGULATOR receiver
KR75_RS19640	COG3136	membrane protein required for alginate biosynthesis
KR75_RS19650	COG0531	amino acid
KR75_RS19660	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
KR75_RS19665	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
KR75_RS19680	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KR75_RS19695	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
KR75_RS19700	COG1473	amidohydrolase
KR75_RS19710	COG0583	DNA-binding transcription factor activity
KR75_RS19715	COG2840	Smr protein MutS2
KR75_RS19720	COG1414	Transcriptional regulator
KR75_RS19730	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
KR75_RS19735	COG0183	Belongs to the thiolase family
KR75_RS19745	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
KR75_RS19750	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
KR75_RS19760	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
KR75_RS19760	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
KR75_RS19780	COG4565	transcriptional regulatory protein
KR75_RS19785	COG3290	protein histidine kinase activity
KR75_RS19800	COG2814	Major facilitator Superfamily
KR75_RS19810	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
KR75_RS19820	COG0679	Auxin Efflux Carrier
KR75_RS19850	COG0628	permease
KR75_RS19870	COG3591	Belongs to the peptidase S1B family
KR75_RS19880	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
KR75_RS19885	COG2814	Major facilitator Superfamily
KR75_RS19890	COG0583	DNA-binding transcription factor activity
KR75_RS19895	COG1940	carbohydrate kinase activity
KR75_RS19900	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
KR75_RS19915	COG3302	dmso reductase anchor subunit
KR75_RS19920	COG0437	4 iron, 4 sulfur cluster binding
KR75_RS19925	COG0243	molybdopterin cofactor binding
KR75_RS19940	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KR75_RS19955	COG2271	Major facilitator Superfamily
KR75_RS19960	COG0246	Mannitol dehydrogenase
KR75_RS19965	COG0589	response to stress
KR75_RS19970	COG1802	Transcriptional regulator
KR75_RS19975	COG4221	oxidoreductase activity
KR75_RS20005	COG0583	DNA-binding transcription factor activity
KR75_RS20010	COG0406	alpha-ribazole phosphatase activity
KR75_RS20020	COG0583	DNA-binding transcription factor activity
KR75_RS20070	COG0071	Belongs to the small heat shock protein (HSP20) family
KR75_RS20075	COG1546	Belongs to the CinA family
KR75_RS20080	COG2200	EAL domain
KR75_RS20090	COG2207	Transcriptional regulator
KR75_RS20090	COG3708	Transcriptional regulator
KR75_RS20095	COG2610	gluconate transmembrane transporter activity
KR75_RS20100	COG3622	Belongs to the hyi family
KR75_RS20105	COG0235	Class ii aldolase
KR75_RS20110	COG3395	kinase activity
KR75_RS20115	COG2084	Dehydrogenase
KR75_RS20120	COG1349	DNA-binding transcription factor activity
KR75_RS20135	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
KR75_RS20140	COG2223	nitrite transmembrane transporter activity
KR75_RS20175	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
KR75_RS20180	COG0683	leucine binding
KR75_RS20210	COG2814	Major facilitator Superfamily
KR75_RS20215	COG0697	spore germination
KR75_RS20225	COG4977	sequence-specific DNA binding
KR75_RS20250	COG2271	Major facilitator Superfamily
KR75_RS20255	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
KR75_RS20260	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KR75_RS20270	COG3395	kinase activity
KR75_RS20275	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
KR75_RS20280	COG1349	DNA-binding transcription factor activity
KR75_RS20285	COG0039	L-malate dehydrogenase activity
KR75_RS20295	COG0583	DNA-binding transcription factor activity
KR75_RS20300	COG1012	belongs to the aldehyde dehydrogenase family
KR75_RS20315	COG2199	diguanylate cyclase activity
KR75_RS20385	COG0477	Major facilitator Superfamily
KR75_RS20395	COG2070	2-Nitropropane dioxygenase
KR75_RS20400	COG2011	ABC-type metal ion transport system permease component
KR75_RS20420	COG4628	conserved protein (DUF2132)
KR75_RS20435	COG2207	Transcriptional regulator
KR75_RS20465	COG2233	PERMEase
KR75_RS20475	COG2351	hydroxyisourate hydrolase activity
KR75_RS20480	COG1396	sequence-specific DNA binding
KR75_RS20485	COG3550	peptidyl-serine autophosphorylation
KR75_RS20490	COG1649	PFAM Uncharacterised BCR, COG1649
KR75_RS20500	COG3188	usher protein
KR75_RS20535	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
KR75_RS20555	COG5001	Diguanylate cyclase
KR75_RS20555	COG3300	MHYT domain
KR75_RS20560	COG2819	hydrolase of the alpha beta superfamily
KR75_RS20570	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
KR75_RS20570	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
KR75_RS20575	COG2814	Major facilitator Superfamily
KR75_RS20585	COG1263	PTS System
KR75_RS20585	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KR75_RS20590	COG2186	Transcriptional regulator
KR75_RS20675	COG3850	Histidine kinase
KR75_RS20675	COG5002	protein histidine kinase activity
KR75_RS20690	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KR75_RS20725	COG0583	DNA-binding transcription factor activity
KR75_RS20730	COG0110	maltose O-acetyltransferase activity
KR75_RS20740	COG1064	alcohol dehydrogenase
KR75_RS20745	COG0702	epimerase
KR75_RS20755	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KR75_RS20760	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KR75_RS20775	COG1064	alcohol dehydrogenase
KR75_RS20780	COG0667	Aldo Keto reductase
KR75_RS20785	COG0656	L-ascorbic acid biosynthetic process
KR75_RS20825	COG5002	protein histidine kinase activity
KR75_RS20840	COG2814	Major facilitator Superfamily
KR75_RS20850	COG0667	Aldo Keto reductase
KR75_RS20865	COG1566	PFAM secretion protein HlyD family protein
KR75_RS20870	COG2814	Major facilitator Superfamily
KR75_RS20880	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KR75_RS20885	COG0601	transmembrane transport
KR75_RS20890	COG0747	negative chemotaxis
KR75_RS20915	COG1609	Transcriptional regulator
KR75_RS20925	COG1172	Belongs to the binding-protein-dependent transport system permease family
KR75_RS20940	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KR75_RS20950	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KR75_RS20955	COG0583	DNA-binding transcription factor activity
KR75_RS20960	COG0583	DNA-binding transcription factor activity
KR75_RS20980	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KR75_RS20990	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
KR75_RS20995	COG3037	sugar-specific permease SgaT UlaA
KR75_RS21005	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
KR75_RS21010	COG1609	Transcriptional regulator
KR75_RS21015	COG0583	DNA-binding transcription factor activity
KR75_RS21020	COG1028	Short-chain dehydrogenase reductase Sdr
KR75_RS21035	COG0439	Biotin carboxylase
KR75_RS21040	COG3665	Urea carboxylase-associated protein
KR75_RS21050	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
KR75_RS21065	COG2223	nitrite transmembrane transporter activity
KR75_RS21095	COG0477	Major facilitator Superfamily
KR75_RS21100	COG4529	Protein conserved in bacteria
KR75_RS21105	COG1902	pentaerythritol trinitrate reductase activity
KR75_RS21115	COG0583	DNA-binding transcription factor activity
KR75_RS21120	COG2070	2-Nitropropane dioxygenase
KR75_RS21130	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
KR75_RS21140	COG0765	amino acid transport
KR75_RS21205	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
KR75_RS21220	COG0583	DNA-binding transcription factor activity
KR75_RS21225	COG3711	transcriptional antiterminator
KR75_RS21230	COG2723	6-phospho-beta-galactosidase activity
KR75_RS21235	COG2190	(PTS) system
KR75_RS21235	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KR75_RS21235	COG1263	PTS System
KR75_RS21255	COG0583	DNA-binding transcription factor activity
KR75_RS21270	COG2207	Transcriptional regulator
KR75_RS21280	COG0604	alcohol dehydrogenase
KR75_RS21280	COG3321	synthase
KR75_RS21280	COG1028	Short-chain dehydrogenase reductase Sdr
KR75_RS21295	COG0596	Alpha beta hydrolase
KR75_RS21330	COG1953	Uracil, thiamine, allantoin
KR75_RS21335	COG0402	S-adenosylhomocysteine deaminase activity
KR75_RS21345	COG3706	GGDEF domain
KR75_RS21350	COG1609	Transcriptional regulator
KR75_RS21360	COG0673	inositol 2-dehydrogenase activity
KR75_RS21385	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
KR75_RS21390	COG1116	anion transmembrane transporter activity
KR75_RS21395	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KR75_RS21400	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KR75_RS21405	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
KR75_RS21410	COG0076	glutamate decarboxylase activity
KR75_RS21440	COG0596	Alpha beta hydrolase
KR75_RS21475	COG0518	GMP synthase (glutamine-hydrolyzing) activity
KR75_RS21475	COG0519	Catalyzes the synthesis of GMP from XMP
KR75_RS21495	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
KR75_RS21500	COG2814	Major facilitator Superfamily
KR75_RS21505	COG0583	DNA-binding transcription factor activity
KR75_RS21510	COG0243	molybdopterin cofactor binding
KR75_RS21515	COG3781	membrane
KR75_RS21520	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
KR75_RS21535	COG1764	response to oxidative stress
KR75_RS21540	COG3111	PFAM Bacterial OB fold (BOF) protein
KR75_RS21550	COG2323	membrane
KR75_RS21560	COG0366	Alpha amylase catalytic
KR75_RS21570	COG3685	Protein conserved in bacteria
KR75_RS21580	COG3729	General stress protein
KR75_RS21585	COG1028	Short-chain dehydrogenase reductase Sdr
KR75_RS21620	COG0488	(ABC) transporter
KR75_RS21635	COG1064	alcohol dehydrogenase
KR75_RS21640	COG0747	negative chemotaxis
KR75_RS21645	COG0601	transmembrane transport
KR75_RS21650	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KR75_RS21660	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KR75_RS21670	COG2814	Major facilitator Superfamily
KR75_RS21680	COG2326	polyphosphate kinase activity
KR75_RS21695	COG2864	formate dehydrogenase
KR75_RS21700	COG0437	4 iron, 4 sulfur cluster binding
KR75_RS21705	COG0243	molybdopterin cofactor binding
KR75_RS21705	COG3383	formate dehydrogenase (NAD+) activity
KR75_RS21710	COG0243	molybdopterin cofactor binding
KR75_RS21710	COG3383	formate dehydrogenase (NAD+) activity
KR75_RS21730	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
KR75_RS21740	COG3485	protocatechuate 3,4-dioxygenase
KR75_RS21745	COG4829	muconolactone delta-isomerase
KR75_RS21750	COG4948	Mandelate Racemase Muconate Lactonizing
KR75_RS21755	COG1414	Transcriptional regulator
KR75_RS21770	COG0210	DNA helicase
KR75_RS21775	COG2162	N-hydroxyarylamine O-acetyltransferase activity
KR75_RS21780	COG1178	ABC-type Fe3 transport system permease component
KR75_RS21785	COG1840	ABC-type Fe3 transport system, periplasmic component
KR75_RS21790	COG3842	ATPase activity
KR75_RS21795	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
KR75_RS21810	COG2211	Major facilitator Superfamily
KR75_RS21825	COG0625	glutathione transferase activity
KR75_RS21830	COG1609	Transcriptional regulator
KR75_RS21840	COG2271	Major facilitator Superfamily
KR75_RS21850	COG1126	abc transporter atp-binding protein
KR75_RS21855	COG0765	amino acid transport
KR75_RS21865	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KR75_RS21870	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KR75_RS21875	COG1473	amidohydrolase
KR75_RS21880	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KR75_RS21885	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
KR75_RS21890	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
KR75_RS21895	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
KR75_RS21920	COG4772	TonB-dependent receptor
KR75_RS21925	COG3691	Protein conserved in bacteria
KR75_RS21935	COG2130	NADP-dependent
KR75_RS21945	COG1247	-acetyltransferase
KR75_RS21950	COG3238	Protein conserved in bacteria
KR75_RS21960	COG0747	negative chemotaxis
KR75_RS21965	COG1012	belongs to the aldehyde dehydrogenase family
KR75_RS21980	COG1012	belongs to the aldehyde dehydrogenase family
KR75_RS21985	COG1177	transmembrane transport
KR75_RS21990	COG1176	ABC-type spermidine putrescine transport system, permease component I
KR75_RS21995	COG3842	ATPase activity
KR75_RS22000	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
KR75_RS22005	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KR75_RS22010	COG1271	oxidase subunit
KR75_RS22015	COG1294	oxidase, subunit
KR75_RS22030	COG0826	peptidase U32
KR75_RS22035	COG1396	sequence-specific DNA binding
KR75_RS22040	COG3135	benzoate transporter
KR75_RS22045	COG2207	Transcriptional regulator
KR75_RS22045	COG3708	Transcriptional regulator
KR75_RS22060	COG0500	methyltransferase
KR75_RS22065	COG1275	C4-dicarboxylate transporter malic acid transport protein
KR75_RS22070	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
KR75_RS22075	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KR75_RS22090	COG2272	Belongs to the type-B carboxylesterase lipase family
KR75_RS22095	COG5383	Protein conserved in bacteria
KR75_RS22100	COG3485	protocatechuate 3,4-dioxygenase
KR75_RS22105	COG3485	protocatechuate 3,4-dioxygenase
KR75_RS22110	COG0583	DNA-binding transcription factor activity
KR75_RS22130	COG3038	cytochrome b561
KR75_RS22150	COG2814	Major facilitator Superfamily
KR75_RS22160	COG0673	inositol 2-dehydrogenase activity
KR75_RS22170	COG2723	6-phospho-beta-galactosidase activity
KR75_RS22205	COG4659	FMN binding
KR75_RS22215	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
KR75_RS22225	COG0625	glutathione transferase activity
KR75_RS22230	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
KR75_RS22245	COG3895	Periplasmic Protein
KR75_RS22260	COG3706	GGDEF domain
KR75_RS22275	COG1566	PFAM secretion protein HlyD family protein
KR75_RS22280	COG1289	transmembrane transporter activity
KR75_RS22285	COG2032	superoxide dismutase activity
KR75_RS22290	COG4989	oxidoreductase activity
KR75_RS22295	COG3313	Fe-S protein
KR75_RS22300	COG1309	transcriptional regulator
KR75_RS22305	COG1902	pentaerythritol trinitrate reductase activity
KR75_RS22310	COG0346	lactoylglutathione lyase activity
KR75_RS22320	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
KR75_RS22325	COG0791	NLP P60 protein
KR75_RS22330	COG2207	Transcriptional regulator
KR75_RS22340	COG2814	Major facilitator Superfamily
KR75_RS22355	COG0583	DNA-binding transcription factor activity
KR75_RS22360	COG2814	Major facilitator Superfamily
KR75_RS22365	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
KR75_RS22370	COG0307	riboflavin synthase, alpha
KR75_RS22410	COG0300	oxidoreductase activity
KR75_RS22430	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
KR75_RS22465	COG1349	DNA-binding transcription factor activity
KR75_RS22470	COG0346	lactoylglutathione lyase activity
KR75_RS22485	COG2011	ABC-type metal ion transport system permease component
KR75_RS22515	COG0444	Belongs to the ABC transporter superfamily
KR75_RS22520	COG4608	Belongs to the ABC transporter superfamily
KR75_RS22575	COG0402	S-adenosylhomocysteine deaminase activity
KR75_RS22600	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KR75_RS22605	COG0277	FAD linked oxidase domain protein
KR75_RS22625	COG2814	Major facilitator Superfamily
KR75_RS22650	COG0583	DNA-binding transcription factor activity
KR75_RS22660	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
KR75_RS22670	COG1250	3-hydroxyacyl-CoA dehydrogenase
KR75_RS22675	COG2610	gluconate transmembrane transporter activity
KR75_RS22680	COG1028	Short-chain dehydrogenase reductase Sdr
KR75_RS22725	COG0583	DNA-binding transcription factor activity
KR75_RS22740	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
KR75_RS22745	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KR75_RS22770	COG4235	cytochrome complex assembly
KR75_RS22770	COG3088	subunit of a heme lyase
KR75_RS22775	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KR75_RS22780	COG1138	Cytochrome C-type biogenesis protein
KR75_RS22795	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
KR75_RS22800	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
KR75_RS22805	COG4133	protoheme IX ABC transporter activity
KR75_RS22835	COG1175	transmembrane transport
KR75_RS22845	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
KR75_RS22850	COG3383	formate dehydrogenase (NAD+) activity
KR75_RS22855	COG1473	amidohydrolase
KR75_RS22870	COG1017	nitric oxide dioxygenase activity
KR75_RS22870	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
KR75_RS22880	COG0860	N-Acetylmuramoyl-L-alanine amidase
KR75_RS22885	COG2814	Major facilitator Superfamily
KR75_RS22900	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KR75_RS22905	COG1121	(ABC) transporter
KR75_RS22915	COG0346	lactoylglutathione lyase activity
KR75_RS22930	COG1116	anion transmembrane transporter activity
KR75_RS22940	COG3119	arylsulfatase activity
KR75_RS22965	COG1126	abc transporter atp-binding protein
KR75_RS22970	COG0765	amino acid transport
KR75_RS22985	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KR75_RS22990	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KR75_RS22995	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KR75_RS23000	COG1120	ATPase activity
KR75_RS23005	COG4774	siderophore transport
KR75_RS23010	COG1116	anion transmembrane transporter activity
KR75_RS23015	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KR75_RS23035	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KR75_RS23040	COG0583	DNA-binding transcription factor activity
KR75_RS23060	COG2814	Major facilitator Superfamily
KR75_RS23095	COG1414	Transcriptional regulator
KR75_RS23100	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KR75_RS23105	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KR75_RS23110	COG1120	ATPase activity
KR75_RS23120	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
KR75_RS23125	COG2271	Major facilitator Superfamily
KR75_RS23130	COG1082	Xylose isomerase domain protein TIM barrel
KR75_RS23130	COG3185	4-Hydroxyphenylpyruvate dioxygenase
KR75_RS23135	COG1309	transcriptional regulator
KR75_RS23155	COG1376	ErfK ybiS ycfS ynhG family protein
KR75_RS23170	COG0719	Fe-S assembly protein
KR75_RS23175	COG0396	ATPase activity
KR75_RS23180	COG0719	Fe-S assembly protein
KR75_RS23185	COG0316	Belongs to the HesB IscA family
KR75_RS23190	COG2200	EAL domain
KR75_RS23205	COG0725	ABC transporter, periplasmic molybdate-binding protein
KR75_RS23210	COG1176	ABC-type spermidine putrescine transport system, permease component I
KR75_RS23215	COG0583	DNA-binding transcription factor activity
KR75_RS23225	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KR75_RS23230	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
KR75_RS23235	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
KR75_RS23270	COG1196	nuclear chromosome segregation
KR75_RS23335	COG5484	DNA packaging
KR75_RS23335	COG3728	DNA packaging
KR75_RS23365	COG3179	chitinase
KR75_RS23450	COG1484	DNA-dependent DNA replication
KR75_RS23495	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
KR75_RS23525	COG0582	viral genome integration into host DNA
KR75_RS23535	COG1304	FMN binding
KR75_RS23560	COG0583	DNA-binding transcription factor activity
KR75_RS23570	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KR75_RS23575	COG1120	ATPase activity
KR75_RS23600	COG2261	transglycosylase associated protein
KR75_RS23605	COG2050	protein possibly involved in aromatic compounds catabolism
KR75_RS23610	COG0247	lactate metabolic process
KR75_RS23610	COG0277	FAD linked oxidase domain protein
KR75_RS23615	COG0628	permease
KR75_RS23620	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
KR75_RS23620	COG0574	Belongs to the PEP-utilizing enzyme family
KR75_RS23630	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
KR75_RS23635	COG4256	Hemin uptake protein
KR75_RS23645	COG0791	NLP P60 protein
KR75_RS23655	COG0386	Belongs to the glutathione peroxidase family
KR75_RS23675	COG0583	DNA-binding transcription factor activity
KR75_RS23685	COG0251	oxidation-reduction process
KR75_RS23695	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KR75_RS23695	COG0072	phenylalanine-tRNA ligase activity
KR75_RS23730	COG3137	Salt-induced outer membrane protein
KR75_RS23735	COG1105	Belongs to the carbohydrate kinase PfkB family
KR75_RS23745	COG3001	Fructosamine kinase
KR75_RS23755	COG2350	Protein conserved in bacteria
KR75_RS23760	COG4993	Dehydrogenase
KR75_RS23765	COG2353	YceI-like domain
KR75_RS23785	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KR75_RS23795	COG0444	Belongs to the ABC transporter superfamily
KR75_RS23800	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KR75_RS23805	COG0601	transmembrane transport
KR75_RS23810	COG4166	transmembrane transport
KR75_RS23815	COG2095	MarC family integral membrane protein
KR75_RS23820	COG1454	alcohol dehydrogenase
KR75_RS23820	COG1012	belongs to the aldehyde dehydrogenase family
KR75_RS23825	COG1435	thymidine kinase activity
KR75_RS23830	COG2916	Histone family protein nucleoid-structuring protein H-NS
KR75_RS23835	COG1210	Utp--glucose-1-phosphate uridylyltransferase
KR75_RS23840	COG0745	RESPONSE REGULATOR receiver
KR75_RS23845	COG1752	Esterase of the alpha-beta hydrolase superfamily
KR75_RS23855	COG0788	formyltetrahydrofolate deformylase activity
KR75_RS23870	COG1522	sequence-specific DNA binding
KR75_RS23880	COG2181	nitrate reductase activity
KR75_RS23885	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
KR75_RS23890	COG1140	nitrate reductase beta subunit
KR75_RS23895	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
KR75_RS23900	COG2223	nitrite transmembrane transporter activity
KR75_RS23905	COG3850	Histidine kinase
KR75_RS23910	COG2197	response regulator
KR75_RS23915	COG4932	domain protein
KR75_RS23920	COG0243	molybdopterin cofactor binding
KR75_RS23925	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KR75_RS23925	COG2146	nitrite reductase [NAD(P)H] activity
KR75_RS23930	COG1116	anion transmembrane transporter activity
KR75_RS23940	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KR75_RS23945	COG3707	response regulator
KR75_RS23950	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
KR75_RS23960	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
KR75_RS23965	COG4572	Cation transport regulator
KR75_RS23970	COG0387	Pfam Sodium calcium exchanger
KR75_RS23990	COG2890	protein-(glutamine-N5) methyltransferase activity
KR75_RS24020	COG0659	secondary active sulfate transmembrane transporter activity
KR75_RS24040	COG0012	GTP binding
KR75_RS24070	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KR75_RS24085	COG0800	Aldolase
KR75_RS24090	COG3734	2-keto-3-deoxy-galactonokinase
KR75_RS24095	COG2186	Transcriptional regulator
KR75_RS24100	COG3122	Protein conserved in bacteria
KR75_RS24105	COG0564	pseudouridine synthase activity
KR75_RS24115	COG0583	DNA-binding transcription factor activity
KR75_RS24145	COG0583	DNA-binding transcription factor activity
KR75_RS24175	COG1882	Formate acetyltransferase
KR75_RS24190	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
KR75_RS24195	COG0583	DNA-binding transcription factor activity
KR75_RS24210	COG1174	glycine betaine transport
KR75_RS24220	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KR75_RS24235	COG1940	carbohydrate kinase activity
KR75_RS24250	COG0395	ABC-type sugar transport system, permease component
KR75_RS24255	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KR75_RS24260	COG3842	ATPase activity
KR75_RS24280	COG2308	Evidence 4 Homologs of previously reported genes of
KR75_RS24295	COG4774	siderophore transport
KR75_RS24315	COG1619	proteins homologs of microcin C7 resistance protein MccF
KR75_RS24335	COG2719	SpoVR family
KR75_RS24365	COG0179	Fumarylacetoacetate (FAA) hydrolase
KR75_RS24380	COG2894	cell division
KR75_RS24390	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
KR75_RS24400	COG3065	identical protein binding
KR75_RS24410	COG1199	ATP-dependent helicase activity
KR75_RS24415	COG0251	oxidation-reduction process
KR75_RS24435	COG1760	l-serine dehydratase
KR75_RS24440	COG2200	EAL domain
KR75_RS24445	COG1253	flavin adenine dinucleotide binding
KR75_RS24450	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
KR75_RS24450	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KR75_RS24455	COG3715	PTS system
KR75_RS24460	COG3716	PTS system mannose fructose sorbose family IID component
KR75_RS24475	COG2226	methyltransferase
KR75_RS24480	COG0768	penicillin binding
KR75_RS24505	COG1414	Transcriptional regulator
KR75_RS24510	COG2814	Major facilitator Superfamily
KR75_RS24530	COG1956	GAF domain-containing protein
KR75_RS24535	COG2995	paraquat-inducible protein a
KR75_RS24540	COG3008	intermembrane lipid transfer
KR75_RS24565	COG2990	Protein conserved in bacteria
KR75_RS24580	COG1276	copper resistance
KR75_RS24585	COG2372	response to copper ion
KR75_RS24595	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
KR75_RS24600	COG1770	oligopeptidase
KR75_RS24605	COG2979	Protein of unknown function (DUF533)
KR75_RS24610	COG3141	response to X-ray
KR75_RS24620	COG0800	Aldolase
KR75_RS24625	COG0129	dihydroxy-acid dehydratase activity
KR75_RS24630	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
KR75_RS24635	COG1737	Transcriptional regulator
KR75_RS24645	COG3493	citrate carrier protein
KR75_RS24665	COG1560	Kdo2-lipid A biosynthetic process
KR75_RS24670	COG0739	heme binding
KR75_RS24675	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
KR75_RS24685	COG1108	ABC-type Mn2 Zn2 transport systems permease components
KR75_RS24710	COG0494	nUDIX hydrolase
KR75_RS24720	COG1335	isochorismatase
KR75_RS24725	COG1801	Protein of unknown function DUF72
KR75_RS24730	COG3788	relative of glutathione S-transferase, MAPEG superfamily
KR75_RS24750	COG3102	Protein conserved in bacteria
KR75_RS24760	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
KR75_RS24785	COG1172	Belongs to the binding-protein-dependent transport system permease family
KR75_RS24795	COG1879	ABC-type sugar transport system periplasmic component
KR75_RS24800	COG1528	Iron-storage protein
KR75_RS24805	COG2211	Major facilitator Superfamily
KR75_RS24815	COG0477	Major facilitator Superfamily
KR75_RS24825	COG1528	Iron-storage protein
KR75_RS24835	COG0814	amino acid
KR75_RS24840	COG3012	SEC-C Motif Domain Protein
KR75_RS24840	COG3318	Belongs to the UPF0149 family
KR75_RS24880	COG2197	response regulator
KR75_RS24890	COG2197	response regulator
KR75_RS24895	COG1126	abc transporter atp-binding protein
KR75_RS24900	COG0765	amino acid transport
KR75_RS24910	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KR75_RS24915	COG0366	Alpha amylase catalytic
KR75_RS24945	COG2354	Protein conserved in bacteria
KR75_RS24950	COG0697	spore germination
KR75_RS24955	COG3727	T/G mismatch-specific endonuclease activity
KR75_RS24960	COG0270	DNA (cytosine-5-)-methyltransferase activity
KR75_RS24965	COG1418	mRNA catabolic process
KR75_RS24975	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
KR75_RS25030	COG1196	nuclear chromosome segregation
KR75_RS25065	COG0740	serine-type endopeptidase activity
KR75_RS25145	COG1403	HNH endonuclease
KR75_RS25150	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
KR75_RS25245	COG0436	Aminotransferase
KR75_RS25250	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KR75_RS25255	COG0371	Dehydrogenase
KR75_RS25260	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
KR75_RS25265	COG0456	acetyltransferase
KR75_RS25270	COG1473	amidohydrolase
KR75_RS25275	COG2079	MmgE PrpD family protein
KR75_RS25280	COG1126	abc transporter atp-binding protein
KR75_RS25285	COG0765	amino acid transport
KR75_RS25300	COG0251	oxidation-reduction process
KR75_RS25335	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
KR75_RS25340	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KR75_RS25360	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
KR75_RS25365	COG1045	serine acetyltransferase
KR75_RS25370	COG0025	NhaP-type Na H and K H
KR75_RS25375	COG1309	transcriptional regulator
KR75_RS25380	COG0604	alcohol dehydrogenase
KR75_RS25400	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
KR75_RS25410	COG0534	Mate efflux family protein
KR75_RS25435	COG3706	GGDEF domain
KR75_RS25460	COG3615	Tellurite resistance protein tehB
KR75_RS25465	COG5001	Diguanylate cyclase
KR75_RS25465	COG3300	MHYT domain
KR75_RS25475	COG0477	Major facilitator Superfamily
KR75_RS25480	COG0095	Lipoate-protein ligase
KR75_RS25485	COG0583	DNA-binding transcription factor activity
KR75_RS25490	COG1942	4-Oxalocrotonate Tautomerase
KR75_RS25500	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
KR75_RS25520	COG1289	transmembrane transporter activity
KR75_RS25535	COG2925	Exonuclease
KR75_RS25540	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
KR75_RS25545	COG0640	Transcriptional regulator
KR75_RS25630	COG2205	protein histidine kinase activity
KR75_RS25635	COG3604	Transcriptional regulator
KR75_RS25650	COG0531	amino acid
KR75_RS25655	COG0583	DNA-binding transcription factor activity
KR75_RS25660	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KR75_RS25685	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
KR75_RS25710	COG0438	transferase activity, transferring glycosyl groups
KR75_RS25770	COG1088	dTDP-glucose 4,6-dehydratase activity
KR75_RS25795	COG0463	Glycosyl transferase, family 2
KR75_RS25970	COG0826	peptidase U32
KR75_RS26155	COG1472	Belongs to the glycosyl hydrolase 3 family
KR75_RS26265	COG1346	cytolysis
KR75_RS26420	COG0523	cobalamin synthesis protein
KR75_RS26740	COG0444	Belongs to the ABC transporter superfamily