locus-tag	class	description
KR75_RS00025	COG0561	phosphatase activity
KR75_RS00040	COG0823	Involved in the tonB-independent uptake of proteins
KR75_RS00045	COG5645	(Lipo)protein
KR75_RS00065	COG2188	Transcriptional regulator
KR75_RS00080	COG2149	membrane
KR75_RS00090	COG0641	radical SAM
KR75_RS00100	COG2610	gluconate transmembrane transporter activity
KR75_RS00105	COG0583	DNA-binding transcription factor activity
KR75_RS00110	COG2814	Major facilitator Superfamily
KR75_RS00130	COG0028	Belongs to the TPP enzyme family
KR75_RS00135	COG0440	acetolactate synthase activity
KR75_RS00140	COG2197	response regulator
KR75_RS00150	COG2271	Major facilitator Superfamily
KR75_RS00185	COG4580	involved in the transport of maltose and maltodextrins
KR75_RS00190	COG1447	Phosphotransferase system cellobiose-specific component IIA
KR75_RS00195	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
KR75_RS00195	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
KR75_RS00205	COG1609	Transcriptional regulator
KR75_RS00215	COG3384	dioxygenase
KR75_RS00220	COG0583	DNA-binding transcription factor activity
KR75_RS00225	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
KR75_RS00230	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
KR75_RS00235	COG2828	Protein conserved in bacteria
KR75_RS00250	COG0697	spore germination
KR75_RS00255	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KR75_RS00255	COG1263	PTS System
KR75_RS00265	COG2814	Major facilitator Superfamily
KR75_RS00275	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KR75_RS00295	COG1309	transcriptional regulator
KR75_RS00305	COG0583	DNA-binding transcription factor activity
KR75_RS00330	COG1464	Belongs to the NlpA lipoprotein family
KR75_RS00345	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
KR75_RS00355	COG1064	alcohol dehydrogenase
KR75_RS00385	COG2211	Major facilitator Superfamily
KR75_RS00390	COG1501	Belongs to the glycosyl hydrolase 31 family
KR75_RS00400	COG1486	melibiose metabolic process
KR75_RS00405	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KR75_RS00405	COG1263	PTS System
KR75_RS00410	COG2982	Protein involved in outer membrane biogenesis
KR75_RS00415	COG2233	PERMEase
KR75_RS00420	COG0786	glutamate:sodium symporter activity
KR75_RS00435	COG3074	FtsZ-dependent cytokinesis
KR75_RS00440	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
KR75_RS00465	COG3152	Membrane
KR75_RS00475	COG1494	fructose-1,6-bisphosphatase
KR75_RS00480	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
KR75_RS00485	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KR75_RS00490	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
KR75_RS00515	COG2860	membrane
KR75_RS00525	COG2169	Transcriptional regulator
KR75_RS00525	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
KR75_RS00535	COG1561	YicC-like family, N-terminal region
KR75_RS00550	COG1131	(ABC) transporter
KR75_RS00585	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
KR75_RS00595	COG0227	Belongs to the bacterial ribosomal protein bL28 family
KR75_RS00620	COG1519	Transferase
KR75_RS00625	COG1216	Glycosyl transferase, family 2
KR75_RS00630	COG0438	transferase activity, transferring glycosyl groups
KR75_RS00640	COG0859	PFAM glycosyl transferase family 9
KR75_RS00665	COG0859	PFAM glycosyl transferase family 9
KR75_RS00680	COG0156	8-amino-7-oxononanoate synthase activity
KR75_RS00690	COG0463	Glycosyl transferase, family 2
KR75_RS00695	COG2861	carbohydrate metabolic process
KR75_RS00700	COG4942	peptidase
KR75_RS00710	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KR75_RS00715	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
KR75_RS00735	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
KR75_RS00745	COG2186	Transcriptional regulator
KR75_RS00765	COG3722	fumarate hydratase activity
KR75_RS00785	COG1566	PFAM secretion protein HlyD family protein
KR75_RS00790	COG0625	glutathione transferase activity
KR75_RS00800	COG3276	selenocysteine insertion sequence binding
KR75_RS00805	COG0235	Class ii aldolase
KR75_RS00810	COG3623	hexulose-6-phosphate isomerase
KR75_RS00815	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
KR75_RS00820	COG1070	Carbohydrate kinase
KR75_RS00825	COG2271	Major facilitator Superfamily
KR75_RS00835	COG2731	YhcH YjgK YiaL family protein
KR75_RS00845	COG1414	Transcriptional regulator
KR75_RS00850	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
KR75_RS00855	COG3977	Valine--pyruvate aminotransferase
KR75_RS00860	COG0366	Alpha amylase catalytic
KR75_RS00865	COG2992	FlgJ-related protein
KR75_RS00870	COG2207	Transcriptional regulator
KR75_RS00870	COG1609	Transcriptional regulator
KR75_RS00875	COG4214	carbohydrate transport
KR75_RS00885	COG4213	ABC transporter substrate-binding protein
KR75_RS00900	COG4682	membrane
KR75_RS00905	COG4682	membrane
KR75_RS00910	COG3274	enterobacterial common antigen metabolic process
KR75_RS00935	COG0488	(ABC) transporter
KR75_RS00940	COG1278	Cold shock
KR75_RS00945	COG2944	sequence-specific DNA binding
KR75_RS00950	COG2814	Major facilitator Superfamily
KR75_RS00970	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KR75_RS00980	COG1609	Transcriptional regulator
KR75_RS00985	COG2885	chlorophyll binding
KR75_RS00990	COG0243	molybdopterin cofactor binding
KR75_RS00995	COG0456	acetyltransferase
KR75_RS01000	COG2818	Glycosylase
KR75_RS01005	COG5571	outer membrane autotransporter
KR75_RS01010	COG2223	nitrite transmembrane transporter activity
KR75_RS01035	COG0747	negative chemotaxis
KR75_RS01040	COG0601	transmembrane transport
KR75_RS01045	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KR75_RS01050	COG0444	Belongs to the ABC transporter superfamily
KR75_RS01055	COG4608	Belongs to the ABC transporter superfamily
KR75_RS01065	COG2894	cell division
KR75_RS01075	COG1215	transferase activity, transferring glycosyl groups
KR75_RS01080	COG0457	Tetratricopeptide repeat
KR75_RS01095	COG2194	sulfuric ester hydrolase activity
KR75_RS01130	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
KR75_RS01135	COG3118	belongs to the thioredoxin family
KR75_RS01135	COG0457	Tetratricopeptide repeat
KR75_RS01140	COG2200	EAL domain
KR75_RS01140	COG2199	diguanylate cyclase activity
KR75_RS01150	COG0612	Peptidase, M16
KR75_RS01160	COG2982	Protein involved in outer membrane biogenesis
KR75_RS01165	COG0477	Major facilitator Superfamily
KR75_RS01170	COG1295	ribonuclease BN
KR75_RS01175	COG0583	DNA-binding transcription factor activity
KR75_RS01180	COG1028	Short-chain dehydrogenase reductase Sdr
KR75_RS01185	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KR75_RS01195	COG1454	alcohol dehydrogenase
KR75_RS01205	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KR75_RS01210	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
KR75_RS01215	COG0671	phosphoesterase, PA-phosphatase related
KR75_RS01235	COG0589	response to stress
KR75_RS01245	COG0306	phosphate transporter
KR75_RS01250	COG2081	HI0933 family
KR75_RS01255	COG2239	Acts as a magnesium transporter
KR75_RS01265	COG1124	(ABC) transporter
KR75_RS01275	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KR75_RS01280	COG0601	transmembrane transport
KR75_RS01285	COG0747	negative chemotaxis
KR75_RS01295	COG3479	Phenolic acid decarboxylase
KR75_RS01335	COG0628	permease
KR75_RS01340	COG0477	Major facilitator Superfamily
KR75_RS01350	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
KR75_RS01365	COG3714	YhhN family
KR75_RS01375	COG3776	membrane
KR75_RS01380	COG0742	ribosomal rna small subunit methyltransferase
KR75_RS01385	COG0552	protein localization to endoplasmic reticulum
KR75_RS01390	COG2884	Cell division ATP-binding protein ftsE
KR75_RS01395	COG2177	Part of the ABC transporter FtsEX involved in
KR75_RS01410	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
KR75_RS01420	COG0683	leucine binding
KR75_RS01430	COG0683	leucine binding
KR75_RS01435	COG0559	Belongs to the binding-protein-dependent transport system permease family
KR75_RS01485	COG0584	glycerophosphoryl diester phosphodiesterase
KR75_RS01495	COG0405	Gamma-glutamyltransferase
KR75_RS01500	COG1247	-acetyltransferase
KR75_RS01510	COG0673	inositol 2-dehydrogenase activity
KR75_RS01515	COG1741	Belongs to the pirin family
KR75_RS01520	COG1609	Transcriptional regulator
KR75_RS01525	COG3265	gluconokinase activity
KR75_RS01530	COG2610	gluconate transmembrane transporter activity
KR75_RS01535	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
KR75_RS01560	COG0058	SHG alpha-glucan phosphorylase activity
KR75_RS01575	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
KR75_RS01590	COG1349	DNA-binding transcription factor activity
KR75_RS01600	COG0058	SHG alpha-glucan phosphorylase activity
KR75_RS01605	COG1640	4-alpha-glucanotransferase
KR75_RS01610	COG2610	gluconate transmembrane transporter activity
KR75_RS01620	COG1040	competence protein
KR75_RS01645	COG1918	ferrous iron import across plasma membrane
KR75_RS01650	COG2183	response to ionizing radiation
KR75_RS01655	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
KR75_RS01680	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
KR75_RS01685	COG1011	Hydrolase
KR75_RS01695	COG0494	nUDIX hydrolase
KR75_RS01700	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
KR75_RS01725	COG4796	Type ii and iii secretion system protein
KR75_RS01740	COG3266	domain, Protein
KR75_RS01745	COG0338	D12 class N6 adenine-specific DNA methyltransferase
KR75_RS01750	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
KR75_RS01775	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KR75_RS01780	COG0402	S-adenosylhomocysteine deaminase activity
KR75_RS01785	COG0738	Major facilitator superfamily
KR75_RS01810	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
KR75_RS01815	COG1289	transmembrane transporter activity
KR75_RS01825	COG1765	OsmC-like protein
KR75_RS01830	COG3954	Phosphoribulokinase
KR75_RS01840	COG0429	hydrolase of the alpha beta-hydrolase fold
KR75_RS01845	COG0488	(ABC) transporter
KR75_RS01860	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
KR75_RS01865	COG1047	Peptidyl-prolyl cis-trans
KR75_RS01875	COG0545	Peptidyl-prolyl cis-trans isomerase
KR75_RS01880	COG2964	Protein conserved in bacteria
KR75_RS01930	COG0051	transcription antitermination factor activity, RNA binding
KR75_RS01955	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
KR75_RS01970	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
KR75_RS02035	COG0201	protein transport
KR75_RS02045	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
KR75_RS02055	COG0202	RNA polymerase activity
KR75_RS02070	COG0789	Transcriptional regulator
KR75_RS02100	COG0758	DNA mediated transformation
KR75_RS02110	COG0551	DNA topoisomerase type I activity
KR75_RS02130	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
KR75_RS02165	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KR75_RS02170	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KR75_RS02175	COG1309	transcriptional regulator
KR75_RS02195	COG4145	pantothenate transmembrane transporter activity
KR75_RS02200	COG3924	membrane
KR75_RS02205	COG0439	Biotin carboxylase
KR75_RS02210	COG0511	ligase activity, forming carbon-carbon bonds
KR75_RS02235	COG2200	EAL domain
KR75_RS02235	COG2199	diguanylate cyclase activity
KR75_RS02240	COG1077	Cell shape determining protein MreB Mrl
KR75_RS02245	COG1792	Involved in formation and maintenance of cell shape
KR75_RS02250	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
KR75_RS02260	COG1530	ribonuclease E activity
KR75_RS02265	COG3164	Protein of unknown function
KR75_RS02270	COG0312	modulator of DNA gyrase
KR75_RS02275	COG0583	DNA-binding transcription factor activity
KR75_RS02290	COG1289	transmembrane transporter activity
KR75_RS02295	COG2732	(Barnase) inhibitor
KR75_RS02320	COG1802	Transcriptional regulator
KR75_RS02330	COG0471	metal ion transport
KR75_RS02335	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
KR75_RS02340	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
KR75_RS02350	COG5016	pyruvate
KR75_RS02350	COG0511	ligase activity, forming carbon-carbon bonds
KR75_RS02365	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KR75_RS02370	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KR75_RS02375	COG3105	Protein conserved in bacteria
KR75_RS02380	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
KR75_RS02395	COG0625	glutathione transferase activity
KR75_RS02400	COG2969	positive regulation of protein catabolic process
KR75_RS02410	COG0493	'glutamate synthase
KR75_RS02415	COG0070	glutamate synthase
KR75_RS02415	COG0069	glutamate synthase activity
KR75_RS02415	COG0067	glutamate synthase
KR75_RS02420	COG1242	4 iron, 4 sulfur cluster binding
KR75_RS02425	COG2271	Major facilitator Superfamily
KR75_RS02430	COG1063	alcohol dehydrogenase
KR75_RS02435	COG1312	Catalyzes the dehydration of D-mannonate
KR75_RS02440	COG5002	protein histidine kinase activity
KR75_RS02440	COG2198	Histidine kinase
KR75_RS02440	COG0784	Response regulator, receiver
KR75_RS02445	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
KR75_RS02450	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KR75_RS02455	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
KR75_RS02465	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
KR75_RS02470	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
KR75_RS02475	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
KR75_RS02480	COG1137	ATPase activity
KR75_RS02485	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
KR75_RS02490	COG3117	lipopolysaccharide transmembrane transporter activity
KR75_RS02495	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
KR75_RS02505	COG0530	calcium, potassium:sodium antiporter activity
KR75_RS02510	COG1127	ABC transporter
KR75_RS02515	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
KR75_RS02520	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
KR75_RS02525	COG2854	intermembrane phospholipid transfer
KR75_RS02530	COG3113	response to antibiotic
KR75_RS02535	COG5007	Belongs to the BolA IbaG family
KR75_RS02545	COG3423	Transcriptional regulator
KR75_RS02550	COG0142	geranyltranstransferase activity
KR75_RS02565	COG0697	spore germination
KR75_RS02575	COG2027	D-alanyl-D-alanine carboxypeptidase
KR75_RS02585	COG1534	Rna-binding protein
KR75_RS02595	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KR75_RS02600	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
KR75_RS02610	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
KR75_RS02650	COG0195	Participates in both transcription termination and antitermination
KR75_RS02695	COG0814	amino acid
KR75_RS02700	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KR75_RS02705	COG0826	peptidase U32
KR75_RS02710	COG0826	peptidase U32
KR75_RS02715	COG3154	lipid carrier protein
KR75_RS02720	COG3153	acetyltransferase
KR75_RS02735	COG0693	protein deglycase activity
KR75_RS02740	COG0702	epimerase
KR75_RS02745	COG0701	Predicted permease
KR75_RS02750	COG2823	Periplasmic or secreted lipoprotein
KR75_RS02770	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
KR75_RS02785	COG1063	alcohol dehydrogenase
KR75_RS02790	COG3775	system Galactitol-specific IIC component
KR75_RS02795	COG3414	Phosphotransferase system galactitol-specific IIB component
KR75_RS02800	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
KR75_RS02810	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
KR75_RS02810	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
KR75_RS02815	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
KR75_RS02815	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KR75_RS02815	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KR75_RS02820	COG1105	Belongs to the carbohydrate kinase PfkB family
KR75_RS02830	COG1349	DNA-binding transcription factor activity
KR75_RS02835	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KR75_RS02840	COG2721	sulfolactate sulfo-lyase activity
KR75_RS02845	COG2271	Major facilitator Superfamily
KR75_RS02855	COG2084	Dehydrogenase
KR75_RS02860	COG1929	Belongs to the glycerate kinase type-1 family
KR75_RS02880	COG1741	Belongs to the pirin family
KR75_RS02885	COG0583	DNA-binding transcription factor activity
KR75_RS02890	COG3152	Membrane
KR75_RS02895	COG0435	Glutathione S-transferase
KR75_RS02900	COG2259	Doxx family
KR75_RS02905	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
KR75_RS02910	COG4575	ribosome binding
KR75_RS02915	COG1422	Protein of unknown function (DUF1090)
KR75_RS02925	COG0586	Pfam SNARE associated Golgi protein
KR75_RS02930	COG2186	Transcriptional regulator
KR75_RS02935	COG2271	Major facilitator Superfamily
KR75_RS02945	COG2721	sulfolactate sulfo-lyase activity
KR75_RS02960	COG0861	Integral membrane protein TerC family
KR75_RS02965	COG0673	inositol 2-dehydrogenase activity
KR75_RS02970	COG1451	nucleotide metabolic process
KR75_RS02975	COG3507	Belongs to the glycosyl hydrolase 43 family
KR75_RS02985	COG2211	Major facilitator Superfamily
KR75_RS02995	COG0446	pyridine nucleotide-disulphide oxidoreductase
KR75_RS02995	COG1902	pentaerythritol trinitrate reductase activity
KR75_RS03045	COG1695	Transcriptional regulator
KR75_RS03050	COG2375	cellular response to nickel ion
KR75_RS03065	COG1461	Dihydroxyacetone kinase
KR75_RS03070	COG2376	Dihydroxyacetone kinase
KR75_RS03090	COG3247	response to pH
KR75_RS03100	COG2198	Histidine kinase
KR75_RS03100	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KR75_RS03100	COG2205	protein histidine kinase activity
KR75_RS03100	COG0784	Response regulator, receiver
KR75_RS03105	COG2197	response regulator
KR75_RS03120	COG1773	rubredoxin
KR75_RS03120	COG0426	domain, Protein
KR75_RS03140	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KR75_RS03145	COG0358	DNA primase activity
KR75_RS03150	COG0828	Belongs to the bacterial ribosomal protein bS21 family
KR75_RS03205	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
KR75_RS03220	COG4991	sh3 domain protein
KR75_RS03225	COG3025	triphosphatase activity
KR75_RS03245	COG2960	long-chain fatty acid transporting porin activity
KR75_RS03260	COG3384	dioxygenase
KR75_RS03265	COG0754	glutathionylspermidine amidase activity
KR75_RS03280	COG0494	nUDIX hydrolase
KR75_RS03285	COG3151	Protein conserved in bacteria
KR75_RS03290	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
KR75_RS03295	COG3150	esterase
KR75_RS03305	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
KR75_RS03310	COG2249	NAD(P)H dehydrogenase (quinone) activity
KR75_RS03315	COG0642	Histidine kinase
KR75_RS03325	COG3111	PFAM Bacterial OB fold (BOF) protein
KR75_RS03330	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
KR75_RS03335	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KR75_RS03340	COG0204	Acyl-transferase
KR75_RS03345	COG2132	Multicopper oxidase
KR75_RS03350	COG1032	radical SAM domain protein
KR75_RS03355	COG0656	L-ascorbic acid biosynthetic process
KR75_RS03360	COG1979	alcohol dehydrogenase
KR75_RS03365	COG2207	Transcriptional regulator
KR75_RS03370	COG0586	Pfam SNARE associated Golgi protein
KR75_RS03375	COG0626	cystathionine gamma-synthase activity
KR75_RS03385	COG0848	biopolymer transport protein
KR75_RS03405	COG0625	glutathione transferase activity
KR75_RS03415	COG0754	glutathionylspermidine amidase activity
KR75_RS03420	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KR75_RS03445	COG0626	cystathionine gamma-synthase activity
KR75_RS03500	COG1811	Na channel or pump
KR75_RS03505	COG1982	Orn Lys Arg decarboxylase major
KR75_RS03510	COG2211	Major facilitator Superfamily
KR75_RS03525	COG1194	a g-specific adenine glycosylase
KR75_RS03535	COG3171	Protein conserved in bacteria
KR75_RS03545	COG0635	Involved in the biosynthesis of porphyrin-containing compound
KR75_RS03560	COG0762	integral membrane protein
KR75_RS03565	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
KR75_RS03570	COG2805	Type II/IV secretion system protein
KR75_RS03590	COG0189	ligase activity
KR75_RS03595	COG1385	rRNA (uridine-N3-)-methyltransferase activity
KR75_RS03600	COG2356	endonuclease I
KR75_RS03610	COG2814	Major facilitator Superfamily
KR75_RS03635	COG0501	Belongs to the peptidase M48B family
KR75_RS03640	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
KR75_RS03655	COG0191	fructose-bisphosphate aldolase activity
KR75_RS03660	COG0668	transmembrane transport
KR75_RS03670	COG2968	Membrane
KR75_RS03685	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
KR75_RS03690	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
KR75_RS03710	COG0006	proline dipeptidase activity
KR75_RS03715	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KR75_RS03720	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KR75_RS03740	COG1028	Short-chain dehydrogenase reductase Sdr
KR75_RS03745	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KR75_RS03765	COG2723	6-phospho-beta-galactosidase activity
KR75_RS03770	COG1737	Transcriptional regulator
KR75_RS03780	COG1272	protein, Hemolysin III
KR75_RS03790	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
KR75_RS03800	COG0716	FMN binding
KR75_RS03805	COG4974	Belongs to the 'phage' integrase family
KR75_RS03815	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
KR75_RS03835	COG4942	peptidase
KR75_RS03845	COG2814	Major facilitator Superfamily
KR75_RS03850	COG0583	DNA-binding transcription factor activity
KR75_RS03860	COG0667	Aldo Keto reductase
KR75_RS03865	COG2249	NAD(P)H dehydrogenase (quinone) activity
KR75_RS03900	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
KR75_RS03905	COG1393	Belongs to the ArsC family
KR75_RS03920	COG1538	Outer membrane efflux protein
KR75_RS03925	COG1289	transmembrane transporter activity
KR75_RS03940	COG3592	Divergent 4Fe-4S mono-cluster
KR75_RS03945	COG2388	GCN5-related N-acetyl-transferase
KR75_RS03955	COG3539	Fimbrial protein
KR75_RS03960	COG3539	Fimbrial protein
KR75_RS03965	COG3539	Fimbrial protein
KR75_RS03970	COG3188	usher protein
KR75_RS03975	COG3121	Chaperone
KR75_RS03980	COG3539	Fimbrial protein
KR75_RS03990	COG4974	Belongs to the 'phage' integrase family
KR75_RS03995	COG0582	viral genome integration into host DNA
KR75_RS04020	COG3121	Chaperone
KR75_RS04025	COG3188	usher protein
KR75_RS04035	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
KR75_RS04040	COG1846	Transcriptional regulator
KR75_RS04045	COG0697	spore germination
KR75_RS04095	COG0667	Aldo Keto reductase
KR75_RS04100	COG0814	amino acid
KR75_RS04115	COG0183	Belongs to the thiolase family
KR75_RS04125	COG0823	Involved in the tonB-independent uptake of proteins
KR75_RS04130	COG1028	Short-chain dehydrogenase reductase Sdr
KR75_RS04135	COG2814	Major facilitator Superfamily
KR75_RS04165	COG3842	ATPase activity
KR75_RS04170	COG0395	ABC-type sugar transport system, permease component
KR75_RS04175	COG1175	transmembrane transport
KR75_RS04180	COG1917	Cupin 2, conserved barrel domain protein
KR75_RS04185	COG1794	racemase activity, acting on amino acids and derivatives
KR75_RS04190	COG0583	DNA-binding transcription factor activity
KR75_RS04200	COG1609	Transcriptional regulator
KR75_RS04205	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
KR75_RS04210	COG2723	6-phospho-beta-galactosidase activity
KR75_RS04215	COG2186	Transcriptional regulator
KR75_RS04225	COG1609	Transcriptional regulator
KR75_RS04245	COG0667	Aldo Keto reductase
KR75_RS04255	COG0861	Integral membrane protein TerC family
KR75_RS04285	COG2165	general secretion pathway protein
KR75_RS04290	COG4795	General secretion pathway protein
KR75_RS04300	COG4967	type IV pilus modification protein PilV
KR75_RS04305	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
KR75_RS04310	COG1025	Belongs to the peptidase M16 family
KR75_RS04315	COG1074	ATP-dependent DNA helicase activity
KR75_RS04320	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
KR75_RS04330	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
KR75_RS04330	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
KR75_RS04335	COG0860	N-Acetylmuramoyl-L-alanine amidase
KR75_RS04340	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
KR75_RS04370	COG4656	Part of a membrane complex involved in electron transport
KR75_RS04375	COG1454	alcohol dehydrogenase
KR75_RS04375	COG1012	belongs to the aldehyde dehydrogenase family
KR75_RS04405	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
KR75_RS04570	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
KR75_RS04575	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
KR75_RS04580	COG2166	iron-sulfur cluster assembly
KR75_RS04585	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
KR75_RS04595	COG0583	DNA-binding transcription factor activity
KR75_RS04600	COG2363	Small membrane protein
KR75_RS04610	COG1349	DNA-binding transcription factor activity
KR75_RS04630	COG0738	Major facilitator superfamily
KR75_RS04635	COG0235	Class ii aldolase
KR75_RS04640	COG1454	alcohol dehydrogenase
KR75_RS04655	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KR75_RS04670	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KR75_RS04675	COG2011	ABC-type metal ion transport system permease component
KR75_RS04680	COG1464	Belongs to the NlpA lipoprotein family
KR75_RS04685	COG0477	Major facilitator Superfamily
KR75_RS04695	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KR75_RS04700	COG1760	l-serine dehydratase
KR75_RS04705	COG0814	amino acid
KR75_RS04710	COG1611	Belongs to the LOG family
KR75_RS04725	COG3098	single-species biofilm formation
KR75_RS04730	COG0564	pseudouridine synthase activity
KR75_RS04735	COG0716	FMN binding
KR75_RS04740	COG2271	Major facilitator Superfamily
KR75_RS04745	COG4948	Mandelate Racemase Muconate Lactonizing
KR75_RS04750	COG4948	Mandelate Racemase Muconate Lactonizing
KR75_RS04755	COG1929	Belongs to the glycerate kinase type-1 family
KR75_RS04760	COG3850	Histidine kinase
KR75_RS04760	COG4999	Histidine kinase
KR75_RS04760	COG2205	protein histidine kinase activity
KR75_RS04760	COG3437	response regulator, receiver
KR75_RS04770	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
KR75_RS04780	COG3956	TIGRFAM MazG family protein
KR75_RS04800	COG0602	queuosine metabolic process
KR75_RS04805	COG0720	synthase
KR75_RS04825	COG2234	aminopeptidase activity
KR75_RS04890	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KR75_RS04915	COG0163	prenyltransferase activity
KR75_RS04920	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
KR75_RS04955	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KR75_RS04960	COG4558	Periplasmic binding protein
KR75_RS04965	COG3720	iron ion transport
KR75_RS04985	COG0679	Auxin Efflux Carrier
KR75_RS05000	COG1108	ABC-type Mn2 Zn2 transport systems permease components
KR75_RS05005	COG1108	ABC-type Mn2 Zn2 transport systems permease components
KR75_RS05010	COG1121	(ABC) transporter
KR75_RS05020	COG1609	Transcriptional regulator
KR75_RS05025	COG1940	carbohydrate kinase activity
KR75_RS05030	COG1447	Phosphotransferase system cellobiose-specific component IIA
KR75_RS05035	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
KR75_RS05040	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
KR75_RS05045	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
KR75_RS05050	COG4580	involved in the transport of maltose and maltodextrins
KR75_RS05060	COG2723	6-phospho-beta-galactosidase activity
KR75_RS05070	COG0309	Hydrogenase expression formation protein (HypE)
KR75_RS05075	COG0409	Hydrogenase expression formation protein
KR75_RS05080	COG0298	carbon dioxide binding
KR75_RS05085	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
KR75_RS05100	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
KR75_RS05105	COG0651	ATP synthesis coupled electron transport
KR75_RS05110	COG0650	Formate hydrogenlyase subunit 4
KR75_RS05115	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
KR75_RS05115	COG3261	NADH dehydrogenase
KR75_RS05120	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
KR75_RS05125	COG3260	NADH ubiquinone oxidoreductase 20
KR75_RS05135	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
KR75_RS05145	COG2723	6-phospho-beta-galactosidase activity
KR75_RS05150	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KR75_RS05150	COG1263	PTS System
KR75_RS05160	COG1609	Transcriptional regulator
KR75_RS05165	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
KR75_RS05170	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
KR75_RS05175	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
KR75_RS05185	COG1414	Transcriptional regulator
KR75_RS05190	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
KR75_RS05195	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
KR75_RS05220	COG1349	DNA-binding transcription factor activity
KR75_RS05225	COG4578	phosphoenolpyruvate-dependent sugar phosphotransferase system
KR75_RS05230	COG1028	Short-chain dehydrogenase reductase Sdr
KR75_RS05240	COG3732	PTS system glucitol sorbitol-specific
KR75_RS05245	COG3730	PTS system glucitol sorbitol-specific
KR75_RS05250	COG2951	lytic endotransglycosylase activity
KR75_RS05255	COG1121	(ABC) transporter
KR75_RS05260	COG1108	ABC-type Mn2 Zn2 transport systems permease components
KR75_RS05265	COG0803	Belongs to the bacterial solute-binding protein 9 family
KR75_RS05270	COG1546	Belongs to the CinA family
KR75_RS05290	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
KR75_RS05320	COG2823	Periplasmic or secreted lipoprotein
KR75_RS05325	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
KR75_RS05330	COG1238	metal cluster binding
KR75_RS05350	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
KR75_RS05355	COG2814	Major facilitator Superfamily
KR75_RS05360	COG1566	PFAM secretion protein HlyD family protein
KR75_RS05365	COG1846	Transcriptional regulator
KR75_RS05375	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
KR75_RS05385	COG4176	ABC-type proline glycine betaine transport system permease component
KR75_RS05400	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KR75_RS05410	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
KR75_RS05415	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
KR75_RS05425	COG4575	ribosome binding
KR75_RS05455	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KR75_RS05460	COG0640	Transcriptional regulator
KR75_RS05470	COG0583	DNA-binding transcription factor activity
KR75_RS05475	COG0671	phosphoesterase, PA-phosphatase related
KR75_RS05480	COG3284	Transcriptional regulator
KR75_RS05495	COG3121	Chaperone
KR75_RS05535	COG1028	Short-chain dehydrogenase reductase Sdr
KR75_RS05545	COG0235	Class ii aldolase
KR75_RS05550	COG1126	abc transporter atp-binding protein
KR75_RS05555	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KR75_RS05630	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KR75_RS05635	COG3708	Transcriptional regulator
KR75_RS05635	COG2207	Transcriptional regulator
KR75_RS05665	COG4974	Belongs to the 'phage' integrase family
KR75_RS05760	COG1475	DNA binding
KR75_RS05770	COG0582	viral genome integration into host DNA
KR75_RS05785	COG2867	negative regulation of translational initiation
KR75_RS05800	COG0497	DNA recombination
KR75_RS05815	COG4536	flavin adenine dinucleotide binding
KR75_RS05820	COG4137	Cytochrome C assembly protein
KR75_RS05825	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
KR75_RS05860	COG2885	chlorophyll binding
KR75_RS05865	COG2199	diguanylate cyclase activity
KR75_RS05875	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
KR75_RS05880	COG0287	Prephenate dehydrogenase
KR75_RS05880	COG1605	Chorismate mutase
KR75_RS05895	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
KR75_RS05900	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
KR75_RS05915	COG0542	response to heat
KR75_RS05945	COG0477	Major facilitator Superfamily
KR75_RS05950	COG5544	Lipoprotein
KR75_RS05955	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KR75_RS05965	COG3148	PFAM DTW domain containing protein
KR75_RS05970	COG3118	belongs to the thioredoxin family
KR75_RS05975	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KR75_RS05990	COG0513	Belongs to the DEAD box helicase family
KR75_RS06000	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
KR75_RS06010	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
KR75_RS06015	COG3026	antisigma factor binding
KR75_RS06020	COG3086	response to oxidative stress
KR75_RS06030	COG0681	Belongs to the peptidase S26 family
KR75_RS06050	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
KR75_RS06060	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
KR75_RS06065	COG1737	Transcriptional regulator
KR75_RS06070	COG0560	Phosphoserine phosphatase
KR75_RS06085	COG0047	phosphoribosylformylglycinamidine synthase activity
KR75_RS06085	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KR75_RS06090	COG2205	protein histidine kinase activity
KR75_RS06095	COG3170	Tfp pilus assembly protein FimV
KR75_RS06100	COG2204	response regulator
KR75_RS06105	COG0347	Belongs to the P(II) protein family
KR75_RS06110	COG1017	nitric oxide dioxygenase activity
KR75_RS06110	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
KR75_RS06120	COG2259	Doxx family
KR75_RS06125	COG2814	Major facilitator Superfamily
KR75_RS06130	COG3711	transcriptional antiterminator
KR75_RS06135	COG3683	transport system, periplasmic component
KR75_RS06140	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
KR75_RS06170	COG0822	iron-sulfur transferase activity
KR75_RS06190	COG0633	Ferredoxin
KR75_RS06195	COG2975	iron-sulfur cluster assembly
KR75_RS06215	COG2897	thiosulfate sulfurtransferase activity
KR75_RS06220	COG2373	Large extracellular alpha-helical protein
KR75_RS06225	COG4953	penicillin-binding protein 1C
KR75_RS06255	COG2976	Protein conserved in bacteria
KR75_RS06275	COG1645	bacterial-type flagellum-dependent swarming motility
KR75_RS06285	COG0516	GMP reductase activity
KR75_RS06285	COG0517	IMP dehydrogenase activity
KR75_RS06310	COG2200	EAL domain
KR75_RS06325	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
KR75_RS06340	COG2723	6-phospho-beta-galactosidase activity
KR75_RS06350	COG2233	PERMEase
KR75_RS06365	COG1393	Belongs to the ArsC family
KR75_RS06370	COG4783	chaperone-mediated protein folding
KR75_RS06375	COG0628	permease
KR75_RS06380	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
KR75_RS06385	COG2716	regulation of RNA biosynthetic process
KR75_RS06395	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
KR75_RS06405	COG2321	neutral zinc metallopeptidase
KR75_RS06410	COG1444	tRNA N-acetyltransferase activity
KR75_RS06415	COG0400	carboxylic ester hydrolase activity
KR75_RS06430	COG1393	Belongs to the ArsC family
KR75_RS06435	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KR75_RS06440	COG0493	'glutamate synthase
KR75_RS06440	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
KR75_RS06450	COG5342	invasion associated locus B
KR75_RS06455	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
KR75_RS06460	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
KR75_RS06470	COG4810	utilization protein
KR75_RS06500	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
KR75_RS06560	COG0860	N-Acetylmuramoyl-L-alanine amidase
KR75_RS06580	COG2837	iron assimilation
KR75_RS06585	COG4150	thiosulfate binding
KR75_RS06590	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
KR75_RS06595	COG4208	sulfate ABC transporter
KR75_RS06600	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
KR75_RS06610	COG4319	ketosteroid isomerase
KR75_RS06645	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
KR75_RS06665	COG3530	Putative quorum-sensing-regulated virulence factor
KR75_RS06670	COG0385	Bile acid
KR75_RS06675	COG0583	DNA-binding transcription factor activity
KR75_RS06715	COG3415	Transposase
KR75_RS06720	COG3415	Transposase
KR75_RS06735	COG2199	diguanylate cyclase activity
KR75_RS06735	COG2200	EAL domain
KR75_RS06740	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KR75_RS06755	COG0667	Aldo Keto reductase
KR75_RS06760	COG3961	Belongs to the TPP enzyme family
KR75_RS06775	COG3279	Response regulator of the LytR AlgR family
KR75_RS06780	COG3275	phosphorelay sensor kinase activity
KR75_RS06790	COG0436	Aminotransferase
KR75_RS06795	COG2807	transmembrane transport
KR75_RS06800	COG0590	tRNA wobble adenosine to inosine editing
KR75_RS06805	COG0583	DNA-binding transcription factor activity
KR75_RS06825	COG2116	formate transmembrane transporter activity
KR75_RS06830	COG2853	Lipoprotein
KR75_RS06840	COG3691	Protein conserved in bacteria
KR75_RS06855	COG2062	phosphohistidine phosphatase, SixA
KR75_RS06880	COG0730	response to heat
KR75_RS06885	COG3101	peptidyl-lysine hydroxylation
KR75_RS06900	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
KR75_RS06910	COG2188	Transcriptional regulator
KR75_RS06920	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
KR75_RS06945	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
KR75_RS06955	COG0586	Pfam SNARE associated Golgi protein
KR75_RS06965	COG0285	dihydrofolate synthase activity
KR75_RS06970	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
KR75_RS06975	COG1286	toxin biosynthetic process
KR75_RS06980	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
KR75_RS06985	COG0163	prenyltransferase activity
KR75_RS07005	COG4160	amino acid transport
KR75_RS07010	COG4598	ABC transporter
KR75_RS07020	COG1090	epimerase
KR75_RS07025	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
KR75_RS07030	COG0625	glutathione transferase activity
KR75_RS07035	COG0625	glutathione transferase activity
KR75_RS07040	COG0622	Phosphoesterase
KR75_RS07045	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
KR75_RS07070	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
KR75_RS07075	COG0471	metal ion transport
KR75_RS07075	COG0490	domain, Protein
KR75_RS07085	COG0436	Aminotransferase
KR75_RS07090	COG0583	DNA-binding transcription factor activity
KR75_RS07135	COG0839	Belongs to the complex I subunit 6 family
KR75_RS07145	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
KR75_RS07150	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
KR75_RS07165	COG2153	protein acetylation
KR75_RS07170	COG1169	isochorismate synthase
KR75_RS07195	COG0318	PFAM AMP-dependent synthetase and ligase
KR75_RS07205	COG5464	transposase or invertase
KR75_RS07220	COG1414	Transcriptional regulator
KR75_RS07230	COG2271	Major facilitator Superfamily
KR75_RS07240	COG0247	lactate metabolic process
KR75_RS07250	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
KR75_RS07255	COG2271	Major facilitator Superfamily
KR75_RS07260	COG0584	glycerophosphoryl diester phosphodiesterase
KR75_RS07265	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
KR75_RS07300	COG0642	Histidine kinase
KR75_RS07300	COG2198	Histidine kinase
KR75_RS07315	COG2169	Transcriptional regulator
KR75_RS07315	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
KR75_RS07320	COG3145	DNA-N1-methyladenine dioxygenase activity
KR75_RS07325	COG4615	Cyclic peptide transporter
KR75_RS07330	COG2239	Acts as a magnesium transporter
KR75_RS07335	COG0659	secondary active sulfate transmembrane transporter activity
KR75_RS07350	COG0628	permease
KR75_RS07365	COG1126	abc transporter atp-binding protein
KR75_RS07370	COG0765	amino acid transport
KR75_RS07375	COG0765	amino acid transport
KR75_RS07390	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KR75_RS07415	COG1349	DNA-binding transcription factor activity
KR75_RS07420	COG0494	nUDIX hydrolase
KR75_RS07440	COG1061	Type III restriction enzyme res subunit
KR75_RS07445	COG1187	pseudouridine synthase activity
KR75_RS07450	COG2814	Major facilitator Superfamily
KR75_RS07460	COG4172	Belongs to the ABC transporter superfamily
KR75_RS07465	COG4239	(ABC) transporter, permease
KR75_RS07470	COG4174	ABC transporter (Permease)
KR75_RS07475	COG4166	transmembrane transport
KR75_RS07480	COG2200	EAL domain
KR75_RS07485	COG0791	NLP P60 protein
KR75_RS07490	COG0671	phosphoesterase, PA-phosphatase related
KR75_RS07495	COG0523	cobalamin synthesis protein
KR75_RS07500	COG0246	Mannitol dehydrogenase
KR75_RS07505	COG1312	Catalyzes the dehydration of D-mannonate
KR75_RS07530	COG1566	PFAM secretion protein HlyD family protein
KR75_RS07535	COG2814	Major facilitator Superfamily
KR75_RS07540	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
KR75_RS07540	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
KR75_RS07545	COG1105	Belongs to the carbohydrate kinase PfkB family
KR75_RS07550	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
KR75_RS07550	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KR75_RS07550	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KR75_RS07560	COG2855	membrane
KR75_RS07565	COG0583	DNA-binding transcription factor activity
KR75_RS07570	COG0833	amino acid
KR75_RS07575	COG4771	TonB-dependent receptor
KR75_RS07590	COG2311	Membrane
KR75_RS07605	COG1129	ABC transporter
KR75_RS07630	COG2949	membrane
KR75_RS07640	COG1346	cytolysis
KR75_RS07650	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KR75_RS07655	COG3659	wide pore channel activity
KR75_RS07670	COG2723	6-phospho-beta-galactosidase activity
KR75_RS07680	COG1538	Outer membrane efflux protein
KR75_RS07685	COG0586	Pfam SNARE associated Golgi protein
KR75_RS07695	COG1686	Belongs to the peptidase S11 family
KR75_RS07705	COG0277	FAD linked oxidase domain protein
KR75_RS07710	COG1472	Belongs to the glycosyl hydrolase 3 family
KR75_RS07715	COG1732	Glycine betaine
KR75_RS07720	COG1174	glycine betaine transport
KR75_RS07725	COG1125	glycine betaine transport
KR75_RS07730	COG1174	glycine betaine transport
KR75_RS07735	COG3275	phosphorelay sensor kinase activity
KR75_RS07745	COG4807	Protein conserved in bacteria
KR75_RS07765	COG5455	response to cobalt ion
KR75_RS07770	COG0583	DNA-binding transcription factor activity
KR75_RS07775	COG2252	PERMEase
KR75_RS07785	COG0583	DNA-binding transcription factor activity
KR75_RS07800	COG0351	phosphomethylpyrimidine kinase
KR75_RS07805	COG1830	Aldolase
KR75_RS07820	COG1070	Carbohydrate kinase
KR75_RS07830	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
KR75_RS07835	COG4948	Mandelate Racemase Muconate Lactonizing
KR75_RS07840	COG0747	negative chemotaxis
KR75_RS07845	COG0601	transmembrane transport
KR75_RS07850	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KR75_RS07855	COG0444	Belongs to the ABC transporter superfamily
KR75_RS07860	COG4608	Belongs to the ABC transporter superfamily
KR75_RS07870	COG0826	peptidase U32
KR75_RS07875	COG0745	RESPONSE REGULATOR receiver
KR75_RS07880	COG2205	protein histidine kinase activity
KR75_RS07905	COG1301	dicarboxylic acid transport
KR75_RS07920	COG5002	protein histidine kinase activity
KR75_RS07925	COG0443	Heat shock 70 kDa protein
KR75_RS07930	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
KR75_RS07945	COG2982	Protein involved in outer membrane biogenesis
KR75_RS07950	COG1253	flavin adenine dinucleotide binding
KR75_RS07990	COG0463	Glycosyl transferase, family 2
KR75_RS08015	COG1088	dTDP-glucose 4,6-dehydratase activity
KR75_RS08075	COG0438	transferase activity, transferring glycosyl groups
KR75_RS08100	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
KR75_RS08125	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KR75_RS08130	COG0583	DNA-binding transcription factor activity
KR75_RS08135	COG0531	amino acid
KR75_RS08150	COG3604	Transcriptional regulator
KR75_RS08155	COG2205	protein histidine kinase activity
KR75_RS08240	COG0640	Transcriptional regulator
KR75_RS08245	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
KR75_RS08250	COG2925	Exonuclease
KR75_RS08265	COG1289	transmembrane transporter activity
KR75_RS08285	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
KR75_RS08295	COG1942	4-Oxalocrotonate Tautomerase
KR75_RS08300	COG0583	DNA-binding transcription factor activity
KR75_RS08305	COG0095	Lipoate-protein ligase
KR75_RS08310	COG0477	Major facilitator Superfamily
KR75_RS08320	COG5001	Diguanylate cyclase
KR75_RS08320	COG3300	MHYT domain
KR75_RS08325	COG3615	Tellurite resistance protein tehB
KR75_RS08350	COG3706	GGDEF domain
KR75_RS08375	COG0534	Mate efflux family protein
KR75_RS08385	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
KR75_RS08405	COG0604	alcohol dehydrogenase
KR75_RS08410	COG1309	transcriptional regulator
KR75_RS08415	COG0025	NhaP-type Na H and K H
KR75_RS08420	COG1045	serine acetyltransferase
KR75_RS08425	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
KR75_RS08445	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KR75_RS08450	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
KR75_RS08485	COG0251	oxidation-reduction process
KR75_RS08500	COG0765	amino acid transport
KR75_RS08505	COG1126	abc transporter atp-binding protein
KR75_RS08510	COG2079	MmgE PrpD family protein
KR75_RS08515	COG1473	amidohydrolase
KR75_RS08520	COG0456	acetyltransferase
KR75_RS08525	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
KR75_RS08530	COG0371	Dehydrogenase
KR75_RS08535	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KR75_RS08540	COG0436	Aminotransferase
KR75_RS08625	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
KR75_RS08630	COG1403	HNH endonuclease
KR75_RS08710	COG0740	serine-type endopeptidase activity
KR75_RS08745	COG1196	nuclear chromosome segregation
KR75_RS08800	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
KR75_RS08810	COG1418	mRNA catabolic process
KR75_RS08815	COG0270	DNA (cytosine-5-)-methyltransferase activity
KR75_RS08820	COG3727	T/G mismatch-specific endonuclease activity
KR75_RS08825	COG0697	spore germination
KR75_RS08830	COG2354	Protein conserved in bacteria
KR75_RS08860	COG0366	Alpha amylase catalytic
KR75_RS08865	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KR75_RS08875	COG0765	amino acid transport
KR75_RS08880	COG1126	abc transporter atp-binding protein
KR75_RS08885	COG2197	response regulator
KR75_RS08895	COG2197	response regulator
KR75_RS08935	COG3012	SEC-C Motif Domain Protein
KR75_RS08935	COG3318	Belongs to the UPF0149 family
KR75_RS08940	COG0814	amino acid
KR75_RS08950	COG1528	Iron-storage protein
KR75_RS08960	COG0477	Major facilitator Superfamily
KR75_RS08970	COG2211	Major facilitator Superfamily
KR75_RS08975	COG1528	Iron-storage protein
KR75_RS08980	COG1879	ABC-type sugar transport system periplasmic component
KR75_RS08990	COG1172	Belongs to the binding-protein-dependent transport system permease family
KR75_RS09015	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
KR75_RS09025	COG3102	Protein conserved in bacteria
KR75_RS09045	COG3788	relative of glutathione S-transferase, MAPEG superfamily
KR75_RS09050	COG1801	Protein of unknown function DUF72
KR75_RS09055	COG1335	isochorismatase
KR75_RS09065	COG0494	nUDIX hydrolase
KR75_RS09090	COG1108	ABC-type Mn2 Zn2 transport systems permease components
KR75_RS09100	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
KR75_RS09105	COG0739	heme binding
KR75_RS09110	COG1560	Kdo2-lipid A biosynthetic process
KR75_RS09130	COG3493	citrate carrier protein
KR75_RS09140	COG1737	Transcriptional regulator
KR75_RS09145	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
KR75_RS09150	COG0129	dihydroxy-acid dehydratase activity
KR75_RS09155	COG0800	Aldolase
KR75_RS09165	COG3141	response to X-ray
KR75_RS09170	COG2979	Protein of unknown function (DUF533)
KR75_RS09175	COG1770	oligopeptidase
KR75_RS09180	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
KR75_RS09190	COG2372	response to copper ion
KR75_RS09195	COG1276	copper resistance
KR75_RS09210	COG2990	Protein conserved in bacteria
KR75_RS09235	COG3008	intermembrane lipid transfer
KR75_RS09240	COG2995	paraquat-inducible protein a
KR75_RS09245	COG1956	GAF domain-containing protein
KR75_RS09265	COG2814	Major facilitator Superfamily
KR75_RS09270	COG1414	Transcriptional regulator
KR75_RS09295	COG0768	penicillin binding
KR75_RS09300	COG2226	methyltransferase
KR75_RS09315	COG3716	PTS system mannose fructose sorbose family IID component
KR75_RS09320	COG3715	PTS system
KR75_RS09325	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KR75_RS09325	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
KR75_RS09330	COG1253	flavin adenine dinucleotide binding
KR75_RS09335	COG2200	EAL domain
KR75_RS09340	COG1760	l-serine dehydratase
KR75_RS09360	COG0251	oxidation-reduction process
KR75_RS09365	COG1199	ATP-dependent helicase activity
KR75_RS09375	COG3065	identical protein binding
KR75_RS09385	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
KR75_RS09395	COG2894	cell division
KR75_RS09410	COG0179	Fumarylacetoacetate (FAA) hydrolase
KR75_RS09440	COG2719	SpoVR family
KR75_RS09460	COG1619	proteins homologs of microcin C7 resistance protein MccF
KR75_RS09480	COG4774	siderophore transport
KR75_RS09495	COG2308	Evidence 4 Homologs of previously reported genes of
KR75_RS09515	COG3842	ATPase activity
KR75_RS09520	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KR75_RS09525	COG0395	ABC-type sugar transport system, permease component
KR75_RS09540	COG1940	carbohydrate kinase activity
KR75_RS09555	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KR75_RS09565	COG1174	glycine betaine transport
KR75_RS09580	COG0583	DNA-binding transcription factor activity
KR75_RS09585	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
KR75_RS09600	COG1882	Formate acetyltransferase
KR75_RS09630	COG0583	DNA-binding transcription factor activity
KR75_RS09660	COG0583	DNA-binding transcription factor activity
KR75_RS09670	COG0564	pseudouridine synthase activity
KR75_RS09675	COG3122	Protein conserved in bacteria
KR75_RS09680	COG2186	Transcriptional regulator
KR75_RS09685	COG3734	2-keto-3-deoxy-galactonokinase
KR75_RS09690	COG0800	Aldolase
KR75_RS09705	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KR75_RS09735	COG0012	GTP binding
KR75_RS09755	COG0659	secondary active sulfate transmembrane transporter activity
KR75_RS09785	COG2890	protein-(glutamine-N5) methyltransferase activity
KR75_RS09805	COG0387	Pfam Sodium calcium exchanger
KR75_RS09810	COG4572	Cation transport regulator
KR75_RS09815	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
KR75_RS09825	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
KR75_RS09830	COG3707	response regulator
KR75_RS09835	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KR75_RS09845	COG1116	anion transmembrane transporter activity
KR75_RS09850	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KR75_RS09850	COG2146	nitrite reductase [NAD(P)H] activity
KR75_RS09855	COG0243	molybdopterin cofactor binding
KR75_RS09860	COG4932	domain protein
KR75_RS09865	COG2197	response regulator
KR75_RS09870	COG3850	Histidine kinase
KR75_RS09875	COG2223	nitrite transmembrane transporter activity
KR75_RS09880	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
KR75_RS09885	COG1140	nitrate reductase beta subunit
KR75_RS09890	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
KR75_RS09895	COG2181	nitrate reductase activity
KR75_RS09905	COG1522	sequence-specific DNA binding
KR75_RS09935	COG0788	formyltetrahydrofolate deformylase activity
KR75_RS09945	COG1752	Esterase of the alpha-beta hydrolase superfamily
KR75_RS09950	COG0745	RESPONSE REGULATOR receiver
KR75_RS09955	COG1210	Utp--glucose-1-phosphate uridylyltransferase
KR75_RS09960	COG2916	Histone family protein nucleoid-structuring protein H-NS
KR75_RS09965	COG1435	thymidine kinase activity
KR75_RS09970	COG1454	alcohol dehydrogenase
KR75_RS09970	COG1012	belongs to the aldehyde dehydrogenase family
KR75_RS09975	COG2095	MarC family integral membrane protein
KR75_RS09980	COG4166	transmembrane transport
KR75_RS09985	COG0601	transmembrane transport
KR75_RS09990	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KR75_RS09995	COG0444	Belongs to the ABC transporter superfamily
KR75_RS10005	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KR75_RS10025	COG2353	YceI-like domain
KR75_RS10030	COG4993	Dehydrogenase
KR75_RS10035	COG2350	Protein conserved in bacteria
KR75_RS10045	COG3001	Fructosamine kinase
KR75_RS10055	COG1105	Belongs to the carbohydrate kinase PfkB family
KR75_RS10060	COG3137	Salt-induced outer membrane protein
KR75_RS10095	COG0072	phenylalanine-tRNA ligase activity
KR75_RS10095	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KR75_RS10105	COG0251	oxidation-reduction process
KR75_RS10115	COG0583	DNA-binding transcription factor activity
KR75_RS10135	COG0386	Belongs to the glutathione peroxidase family
KR75_RS10145	COG0791	NLP P60 protein
KR75_RS10155	COG4256	Hemin uptake protein
KR75_RS10160	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
KR75_RS10170	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
KR75_RS10170	COG0574	Belongs to the PEP-utilizing enzyme family
KR75_RS10180	COG0628	permease
KR75_RS10185	COG0277	FAD linked oxidase domain protein
KR75_RS10185	COG0247	lactate metabolic process
KR75_RS10190	COG2050	protein possibly involved in aromatic compounds catabolism
KR75_RS10195	COG2261	transglycosylase associated protein
KR75_RS10220	COG1120	ATPase activity
KR75_RS10225	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KR75_RS10235	COG0583	DNA-binding transcription factor activity
KR75_RS10260	COG1304	FMN binding
KR75_RS10270	COG0582	viral genome integration into host DNA
KR75_RS10300	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
KR75_RS10345	COG1484	DNA-dependent DNA replication
KR75_RS10425	COG3179	chitinase
KR75_RS10455	COG5484	DNA packaging
KR75_RS10455	COG3728	DNA packaging
KR75_RS10520	COG1196	nuclear chromosome segregation
KR75_RS10555	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
KR75_RS10560	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
KR75_RS10565	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KR75_RS10575	COG0583	DNA-binding transcription factor activity
KR75_RS10580	COG1176	ABC-type spermidine putrescine transport system, permease component I
KR75_RS10585	COG0725	ABC transporter, periplasmic molybdate-binding protein
KR75_RS10600	COG2200	EAL domain
KR75_RS10605	COG0316	Belongs to the HesB IscA family
KR75_RS10610	COG0719	Fe-S assembly protein
KR75_RS10615	COG0396	ATPase activity
KR75_RS10620	COG0719	Fe-S assembly protein
KR75_RS10635	COG1376	ErfK ybiS ycfS ynhG family protein
KR75_RS10655	COG1309	transcriptional regulator
KR75_RS10660	COG3185	4-Hydroxyphenylpyruvate dioxygenase
KR75_RS10660	COG1082	Xylose isomerase domain protein TIM barrel
KR75_RS10665	COG2271	Major facilitator Superfamily
KR75_RS10670	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
KR75_RS10680	COG1120	ATPase activity
KR75_RS10685	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KR75_RS10690	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KR75_RS10695	COG1414	Transcriptional regulator
KR75_RS10730	COG2814	Major facilitator Superfamily
KR75_RS10750	COG0583	DNA-binding transcription factor activity
KR75_RS10755	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KR75_RS10775	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KR75_RS10780	COG1116	anion transmembrane transporter activity
KR75_RS10785	COG4774	siderophore transport
KR75_RS10790	COG1120	ATPase activity
KR75_RS10795	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KR75_RS10800	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KR75_RS10805	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KR75_RS10820	COG0765	amino acid transport
KR75_RS10825	COG1126	abc transporter atp-binding protein
KR75_RS10850	COG3119	arylsulfatase activity
KR75_RS10860	COG1116	anion transmembrane transporter activity
KR75_RS10875	COG0346	lactoylglutathione lyase activity
KR75_RS10885	COG1121	(ABC) transporter
KR75_RS10890	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KR75_RS10905	COG2814	Major facilitator Superfamily
KR75_RS10910	COG0860	N-Acetylmuramoyl-L-alanine amidase
KR75_RS10920	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
KR75_RS10920	COG1017	nitric oxide dioxygenase activity
KR75_RS10935	COG1473	amidohydrolase
KR75_RS10940	COG3383	formate dehydrogenase (NAD+) activity
KR75_RS10945	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
KR75_RS10955	COG1175	transmembrane transport
KR75_RS10985	COG4133	protoheme IX ABC transporter activity
KR75_RS10990	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
KR75_RS10995	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
KR75_RS11010	COG1138	Cytochrome C-type biogenesis protein
KR75_RS11015	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KR75_RS11020	COG3088	subunit of a heme lyase
KR75_RS11020	COG4235	cytochrome complex assembly
KR75_RS11050	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KR75_RS11055	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
KR75_RS11070	COG0583	DNA-binding transcription factor activity
KR75_RS11115	COG1028	Short-chain dehydrogenase reductase Sdr
KR75_RS11120	COG2610	gluconate transmembrane transporter activity
KR75_RS11125	COG1250	3-hydroxyacyl-CoA dehydrogenase
KR75_RS11135	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
KR75_RS11145	COG0583	DNA-binding transcription factor activity
KR75_RS11170	COG2814	Major facilitator Superfamily
KR75_RS11190	COG0277	FAD linked oxidase domain protein
KR75_RS11195	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KR75_RS11220	COG0402	S-adenosylhomocysteine deaminase activity
KR75_RS11275	COG4608	Belongs to the ABC transporter superfamily
KR75_RS11280	COG0444	Belongs to the ABC transporter superfamily
KR75_RS11310	COG2011	ABC-type metal ion transport system permease component
KR75_RS11325	COG0346	lactoylglutathione lyase activity
KR75_RS11330	COG1349	DNA-binding transcription factor activity
KR75_RS11365	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
KR75_RS11385	COG0300	oxidoreductase activity
KR75_RS11420	COG0307	riboflavin synthase, alpha
KR75_RS11425	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
KR75_RS11430	COG2814	Major facilitator Superfamily
KR75_RS11435	COG0583	DNA-binding transcription factor activity
KR75_RS11445	COG2814	Major facilitator Superfamily
KR75_RS11455	COG2207	Transcriptional regulator
KR75_RS11460	COG0791	NLP P60 protein
KR75_RS11465	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
KR75_RS11475	COG0346	lactoylglutathione lyase activity
KR75_RS11480	COG1902	pentaerythritol trinitrate reductase activity
KR75_RS11485	COG1309	transcriptional regulator
KR75_RS11490	COG3313	Fe-S protein
KR75_RS11495	COG4989	oxidoreductase activity
KR75_RS11500	COG2032	superoxide dismutase activity
KR75_RS11505	COG1289	transmembrane transporter activity
KR75_RS11510	COG1566	PFAM secretion protein HlyD family protein
KR75_RS11525	COG3706	GGDEF domain
KR75_RS11540	COG3895	Periplasmic Protein
KR75_RS11555	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
KR75_RS11560	COG0625	glutathione transferase activity
KR75_RS11570	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
KR75_RS11580	COG4659	FMN binding
KR75_RS11615	COG2723	6-phospho-beta-galactosidase activity
KR75_RS11625	COG0673	inositol 2-dehydrogenase activity
KR75_RS11635	COG2814	Major facilitator Superfamily
KR75_RS11655	COG3038	cytochrome b561
KR75_RS11675	COG0583	DNA-binding transcription factor activity
KR75_RS11680	COG3485	protocatechuate 3,4-dioxygenase
KR75_RS11685	COG3485	protocatechuate 3,4-dioxygenase
KR75_RS11690	COG5383	Protein conserved in bacteria
KR75_RS11695	COG2272	Belongs to the type-B carboxylesterase lipase family
KR75_RS11710	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KR75_RS11715	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
KR75_RS11720	COG1275	C4-dicarboxylate transporter malic acid transport protein
KR75_RS11725	COG0500	methyltransferase
KR75_RS11735	COG0697	spore germination
KR75_RS11740	COG2207	Transcriptional regulator
KR75_RS11740	COG3708	Transcriptional regulator
KR75_RS11745	COG3135	benzoate transporter
KR75_RS11750	COG1396	sequence-specific DNA binding
KR75_RS11755	COG0826	peptidase U32
KR75_RS11775	COG1294	oxidase, subunit
KR75_RS11780	COG1271	oxidase subunit
KR75_RS11785	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KR75_RS11790	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
KR75_RS11795	COG3842	ATPase activity
KR75_RS11800	COG1176	ABC-type spermidine putrescine transport system, permease component I
KR75_RS11805	COG1177	transmembrane transport
KR75_RS11810	COG1012	belongs to the aldehyde dehydrogenase family
KR75_RS11835	COG1012	belongs to the aldehyde dehydrogenase family
KR75_RS11840	COG0747	negative chemotaxis
KR75_RS11850	COG3238	Protein conserved in bacteria
KR75_RS11855	COG1247	-acetyltransferase
KR75_RS11865	COG2130	NADP-dependent
KR75_RS11875	COG3691	Protein conserved in bacteria
KR75_RS11880	COG4772	TonB-dependent receptor
KR75_RS11905	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
KR75_RS11910	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
KR75_RS11915	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
KR75_RS11920	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KR75_RS11925	COG1473	amidohydrolase
KR75_RS11930	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KR75_RS11935	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KR75_RS11945	COG0765	amino acid transport
KR75_RS11950	COG1126	abc transporter atp-binding protein
KR75_RS11960	COG2271	Major facilitator Superfamily
KR75_RS11970	COG1609	Transcriptional regulator
KR75_RS11975	COG0625	glutathione transferase activity
KR75_RS11990	COG2211	Major facilitator Superfamily
KR75_RS12005	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
KR75_RS12010	COG3842	ATPase activity
KR75_RS12015	COG1840	ABC-type Fe3 transport system, periplasmic component
KR75_RS12020	COG1178	ABC-type Fe3 transport system permease component
KR75_RS12025	COG2162	N-hydroxyarylamine O-acetyltransferase activity
KR75_RS12030	COG0210	DNA helicase
KR75_RS12045	COG1414	Transcriptional regulator
KR75_RS12050	COG4948	Mandelate Racemase Muconate Lactonizing
KR75_RS12055	COG4829	muconolactone delta-isomerase
KR75_RS12060	COG3485	protocatechuate 3,4-dioxygenase
KR75_RS12070	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
KR75_RS12090	COG0243	molybdopterin cofactor binding
KR75_RS12090	COG3383	formate dehydrogenase (NAD+) activity
KR75_RS12095	COG3383	formate dehydrogenase (NAD+) activity
KR75_RS12095	COG0243	molybdopterin cofactor binding
KR75_RS12100	COG0437	4 iron, 4 sulfur cluster binding
KR75_RS12105	COG2864	formate dehydrogenase
KR75_RS12120	COG2326	polyphosphate kinase activity
KR75_RS12130	COG2814	Major facilitator Superfamily
KR75_RS12140	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KR75_RS12150	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KR75_RS12155	COG0601	transmembrane transport
KR75_RS12160	COG0747	negative chemotaxis
KR75_RS12165	COG1064	alcohol dehydrogenase
KR75_RS12180	COG0488	(ABC) transporter
KR75_RS12215	COG1028	Short-chain dehydrogenase reductase Sdr
KR75_RS12220	COG3729	General stress protein
KR75_RS12230	COG3685	Protein conserved in bacteria
KR75_RS12240	COG0366	Alpha amylase catalytic
KR75_RS12250	COG2323	membrane
KR75_RS12260	COG3111	PFAM Bacterial OB fold (BOF) protein
KR75_RS12265	COG1764	response to oxidative stress
KR75_RS12280	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
KR75_RS12285	COG3781	membrane
KR75_RS12290	COG0243	molybdopterin cofactor binding
KR75_RS12295	COG0583	DNA-binding transcription factor activity
KR75_RS12300	COG2814	Major facilitator Superfamily
KR75_RS12305	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
KR75_RS12325	COG0518	GMP synthase (glutamine-hydrolyzing) activity
KR75_RS12325	COG0519	Catalyzes the synthesis of GMP from XMP
KR75_RS12360	COG0596	Alpha beta hydrolase
KR75_RS12385	COG0076	glutamate decarboxylase activity
KR75_RS12390	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
KR75_RS12395	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KR75_RS12400	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KR75_RS12405	COG1116	anion transmembrane transporter activity
KR75_RS12410	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
KR75_RS12430	COG0673	inositol 2-dehydrogenase activity
KR75_RS12440	COG1609	Transcriptional regulator
KR75_RS12445	COG3706	GGDEF domain
KR75_RS12455	COG0402	S-adenosylhomocysteine deaminase activity
KR75_RS12460	COG1953	Uracil, thiamine, allantoin
KR75_RS12495	COG0596	Alpha beta hydrolase
KR75_RS12505	COG3321	synthase
KR75_RS12505	COG1028	Short-chain dehydrogenase reductase Sdr
KR75_RS12505	COG0604	alcohol dehydrogenase
KR75_RS12515	COG2207	Transcriptional regulator
KR75_RS12530	COG0583	DNA-binding transcription factor activity
KR75_RS12550	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KR75_RS12550	COG2190	(PTS) system
KR75_RS12550	COG1263	PTS System
KR75_RS12555	COG2723	6-phospho-beta-galactosidase activity
KR75_RS12560	COG3711	transcriptional antiterminator
KR75_RS12565	COG0583	DNA-binding transcription factor activity
KR75_RS12580	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
KR75_RS12645	COG0765	amino acid transport
KR75_RS12655	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
KR75_RS12665	COG2070	2-Nitropropane dioxygenase
KR75_RS12670	COG0583	DNA-binding transcription factor activity
KR75_RS12680	COG1902	pentaerythritol trinitrate reductase activity
KR75_RS12685	COG4529	Protein conserved in bacteria
KR75_RS12690	COG0477	Major facilitator Superfamily
KR75_RS12720	COG2223	nitrite transmembrane transporter activity
KR75_RS12735	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
KR75_RS12745	COG3665	Urea carboxylase-associated protein
KR75_RS12750	COG0439	Biotin carboxylase
KR75_RS12765	COG1028	Short-chain dehydrogenase reductase Sdr
KR75_RS12770	COG0583	DNA-binding transcription factor activity
KR75_RS12775	COG1609	Transcriptional regulator
KR75_RS12780	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
KR75_RS12790	COG3037	sugar-specific permease SgaT UlaA
KR75_RS12795	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
KR75_RS12805	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KR75_RS12825	COG0583	DNA-binding transcription factor activity
KR75_RS12830	COG0583	DNA-binding transcription factor activity
KR75_RS12835	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KR75_RS12845	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KR75_RS12860	COG1172	Belongs to the binding-protein-dependent transport system permease family
KR75_RS12870	COG1609	Transcriptional regulator
KR75_RS12895	COG0747	negative chemotaxis
KR75_RS12900	COG0601	transmembrane transport
KR75_RS12905	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KR75_RS12915	COG2814	Major facilitator Superfamily
KR75_RS12920	COG1566	PFAM secretion protein HlyD family protein
KR75_RS12935	COG0667	Aldo Keto reductase
KR75_RS12945	COG2814	Major facilitator Superfamily
KR75_RS12960	COG5002	protein histidine kinase activity
KR75_RS13000	COG0656	L-ascorbic acid biosynthetic process
KR75_RS13005	COG0667	Aldo Keto reductase
KR75_RS13010	COG1064	alcohol dehydrogenase
KR75_RS13020	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KR75_RS13025	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KR75_RS13035	COG0702	epimerase
KR75_RS13040	COG1064	alcohol dehydrogenase
KR75_RS13050	COG0110	maltose O-acetyltransferase activity
KR75_RS13055	COG0583	DNA-binding transcription factor activity
KR75_RS13095	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KR75_RS13110	COG3850	Histidine kinase
KR75_RS13110	COG5002	protein histidine kinase activity
KR75_RS13195	COG2186	Transcriptional regulator
KR75_RS13200	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KR75_RS13200	COG1263	PTS System
KR75_RS13210	COG2814	Major facilitator Superfamily
KR75_RS13215	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
KR75_RS13215	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
KR75_RS13225	COG2819	hydrolase of the alpha beta superfamily
KR75_RS13230	COG3300	MHYT domain
KR75_RS13230	COG5001	Diguanylate cyclase
KR75_RS13250	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
KR75_RS13280	COG3188	usher protein
KR75_RS13290	COG1649	PFAM Uncharacterised BCR, COG1649
KR75_RS13295	COG3550	peptidyl-serine autophosphorylation
KR75_RS13300	COG1396	sequence-specific DNA binding
KR75_RS13305	COG2351	hydroxyisourate hydrolase activity
KR75_RS13315	COG2233	PERMEase
KR75_RS13345	COG2207	Transcriptional regulator
KR75_RS13360	COG4628	conserved protein (DUF2132)
KR75_RS13380	COG2011	ABC-type metal ion transport system permease component
KR75_RS13385	COG2070	2-Nitropropane dioxygenase
KR75_RS13395	COG0477	Major facilitator Superfamily
KR75_RS13465	COG2199	diguanylate cyclase activity
KR75_RS13480	COG1012	belongs to the aldehyde dehydrogenase family
KR75_RS13485	COG0583	DNA-binding transcription factor activity
KR75_RS13495	COG0039	L-malate dehydrogenase activity
KR75_RS13500	COG1349	DNA-binding transcription factor activity
KR75_RS13505	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
KR75_RS13510	COG3395	kinase activity
KR75_RS13520	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KR75_RS13525	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
KR75_RS13530	COG2271	Major facilitator Superfamily
KR75_RS13555	COG4977	sequence-specific DNA binding
KR75_RS13565	COG0697	spore germination
KR75_RS13570	COG2814	Major facilitator Superfamily
KR75_RS13600	COG0683	leucine binding
KR75_RS13605	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
KR75_RS13640	COG2223	nitrite transmembrane transporter activity
KR75_RS13645	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
KR75_RS13660	COG1349	DNA-binding transcription factor activity
KR75_RS13665	COG2084	Dehydrogenase
KR75_RS13670	COG3395	kinase activity
KR75_RS13675	COG0235	Class ii aldolase
KR75_RS13680	COG3622	Belongs to the hyi family
KR75_RS13685	COG2610	gluconate transmembrane transporter activity
KR75_RS13690	COG2207	Transcriptional regulator
KR75_RS13690	COG3708	Transcriptional regulator
KR75_RS13700	COG2200	EAL domain
KR75_RS13705	COG1546	Belongs to the CinA family
KR75_RS13710	COG0071	Belongs to the small heat shock protein (HSP20) family
KR75_RS13760	COG0583	DNA-binding transcription factor activity
KR75_RS13770	COG0406	alpha-ribazole phosphatase activity
KR75_RS13775	COG0583	DNA-binding transcription factor activity
KR75_RS13805	COG4221	oxidoreductase activity
KR75_RS13810	COG1802	Transcriptional regulator
KR75_RS13815	COG0589	response to stress
KR75_RS13820	COG0246	Mannitol dehydrogenase
KR75_RS13825	COG2271	Major facilitator Superfamily
KR75_RS13840	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KR75_RS13855	COG0243	molybdopterin cofactor binding
KR75_RS13860	COG0437	4 iron, 4 sulfur cluster binding
KR75_RS13865	COG3302	dmso reductase anchor subunit
KR75_RS13880	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
KR75_RS13885	COG1940	carbohydrate kinase activity
KR75_RS13890	COG0583	DNA-binding transcription factor activity
KR75_RS13895	COG2814	Major facilitator Superfamily
KR75_RS13900	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
KR75_RS13910	COG3591	Belongs to the peptidase S1B family
KR75_RS13930	COG0628	permease
KR75_RS13960	COG0679	Auxin Efflux Carrier
KR75_RS13970	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
KR75_RS13980	COG2814	Major facilitator Superfamily
KR75_RS13995	COG3290	protein histidine kinase activity
KR75_RS14000	COG4565	transcriptional regulatory protein
KR75_RS14020	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
KR75_RS14020	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
KR75_RS14030	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
KR75_RS14035	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
KR75_RS14045	COG0183	Belongs to the thiolase family
KR75_RS14050	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
KR75_RS14060	COG1414	Transcriptional regulator
KR75_RS14065	COG2840	Smr protein MutS2
KR75_RS14070	COG0583	DNA-binding transcription factor activity
KR75_RS14080	COG1473	amidohydrolase
KR75_RS14085	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
KR75_RS14100	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KR75_RS14115	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
KR75_RS14120	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
KR75_RS14130	COG0531	amino acid
KR75_RS14140	COG3136	membrane protein required for alginate biosynthesis
KR75_RS14145	COG0745	RESPONSE REGULATOR receiver
KR75_RS14155	COG1028	Short-chain dehydrogenase reductase Sdr
KR75_RS14160	COG2205	protein histidine kinase activity
KR75_RS14170	COG0114	fumarate hydratase activity
KR75_RS14175	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
KR75_RS14175	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
KR75_RS14180	COG1482	cell wall glycoprotein biosynthetic process
KR75_RS14185	COG5339	Protein conserved in bacteria
KR75_RS14190	COG1609	Transcriptional regulator
KR75_RS14195	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KR75_RS14195	COG1263	PTS System
KR75_RS14200	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
KR75_RS14230	COG0425	Belongs to the sulfur carrier protein TusA family
KR75_RS14235	COG5562	phage envelope protein
KR75_RS14240	COG0401	homolog of Blt101
KR75_RS14245	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
KR75_RS14250	COG1012	belongs to the aldehyde dehydrogenase family
KR75_RS14255	COG1434	Gram-negative-bacterium-type cell wall biogenesis
KR75_RS14260	COG0477	Major facilitator Superfamily
KR75_RS14265	COG1113	amino acid transport
KR75_RS14270	COG2988	succinylglutamate desuccinylase activity
KR75_RS14275	COG3724	N-succinylarginine dihydrolase activity
KR75_RS14280	COG1012	belongs to the aldehyde dehydrogenase family
KR75_RS14285	COG3138	arginine N-succinyltransferase
KR75_RS14290	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
KR75_RS14295	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
KR75_RS14310	COG0183	Belongs to the thiolase family
KR75_RS14320	COG0667	Aldo Keto reductase
KR75_RS14325	COG2814	Major facilitator Superfamily
KR75_RS14330	COG0667	Aldo Keto reductase
KR75_RS14335	COG0583	DNA-binding transcription factor activity
KR75_RS14360	COG4122	O-methyltransferase activity
KR75_RS14370	COG1643	Atp-dependent helicase
KR75_RS14380	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system
KR75_RS14390	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
KR75_RS14395	COG3327	negative regulation of DNA-templated transcription, initiation
KR75_RS14400	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
KR75_RS14405	COG0183	Belongs to the thiolase family
KR75_RS14410	COG2050	protein possibly involved in aromatic compounds catabolism
KR75_RS14415	COG1250	3-hydroxyacyl-CoA dehydrogenase
KR75_RS14420	COG1024	Enoyl-CoA hydratase
KR75_RS14425	COG1024	Enoyl-CoA hydratase
KR75_RS14430	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
KR75_RS14435	COG2151	metal-sulfur cluster biosynthetic enzyme
KR75_RS14440	COG3396	Phenylacetate-CoA oxygenase
KR75_RS14445	COG3460	Phenylacetate-CoA oxygenase
KR75_RS14450	COG3396	Phenylacetate-CoA oxygenase
KR75_RS14455	COG2030	dehydratase
KR75_RS14455	COG1012	belongs to the aldehyde dehydrogenase family
KR75_RS14475	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KR75_RS14490	COG2072	flavoprotein involved in K transport
KR75_RS14495	COG0583	DNA-binding transcription factor activity
KR75_RS14500	COG1126	abc transporter atp-binding protein
KR75_RS14510	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KR75_RS14525	COG1012	belongs to the aldehyde dehydrogenase family
KR75_RS14530	COG2207	Transcriptional regulator
KR75_RS14535	COG3784	Protein of unknown function (DUF1318)
KR75_RS14545	COG2911	Protein conserved in bacteria
KR75_RS14550	COG0586	Pfam SNARE associated Golgi protein
KR75_RS14555	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KR75_RS14560	COG3187	Heat shock protein
KR75_RS14565	COG3042	response to heat
KR75_RS14570	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
KR75_RS14570	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
KR75_RS14570	COG1013	pyruvate-flavodoxin oxidoreductase activity
KR75_RS14570	COG0674	pyruvate-flavodoxin oxidoreductase activity
KR75_RS14575	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
KR75_RS14585	COG0589	response to stress
KR75_RS14595	COG0513	Belongs to the DEAD box helicase family
KR75_RS14605	COG1349	DNA-binding transcription factor activity
KR75_RS14610	COG0673	inositol 2-dehydrogenase activity
KR75_RS14625	COG1113	amino acid transport
KR75_RS14630	COG1522	sequence-specific DNA binding
KR75_RS14640	COG1448	Aminotransferase
KR75_RS14645	COG2011	ABC-type metal ion transport system permease component
KR75_RS14655	COG1464	Belongs to the NlpA lipoprotein family
KR75_RS14660	COG0436	Aminotransferase
KR75_RS14665	COG0604	alcohol dehydrogenase
KR75_RS14690	COG0583	DNA-binding transcription factor activity
KR75_RS14710	COG1028	Short-chain dehydrogenase reductase Sdr
KR75_RS14715	COG1309	transcriptional regulator
KR75_RS14720	COG1028	Short-chain dehydrogenase reductase Sdr
KR75_RS14785	COG2885	chlorophyll binding
KR75_RS14810	COG0693	protein deglycase activity
KR75_RS14815	COG1028	Short-chain dehydrogenase reductase Sdr
KR75_RS14820	COG0583	DNA-binding transcription factor activity
KR75_RS14880	COG3250	beta-galactosidase activity
KR75_RS14885	COG0656	L-ascorbic acid biosynthetic process
KR75_RS14925	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KR75_RS14930	COG0583	DNA-binding transcription factor activity
KR75_RS14935	COG0583	DNA-binding transcription factor activity
KR75_RS14940	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KR75_RS14950	COG0765	amino acid transport
KR75_RS14960	COG4166	transmembrane transport
KR75_RS14965	COG2866	Carboxypeptidase
KR75_RS14970	COG4948	Mandelate Racemase Muconate Lactonizing
KR75_RS14975	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
KR75_RS14980	COG3180	Ammonia monooxygenase
KR75_RS14995	COG3106	COG3106 Predicted ATPase
KR75_RS15005	COG1983	PspC domain protein
KR75_RS15015	COG1842	Phage shock protein A
KR75_RS15020	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
KR75_RS15030	COG1473	amidohydrolase
KR75_RS15045	COG0702	epimerase
KR75_RS15060	COG4171	peptide transport system, permease
KR75_RS15075	COG2986	histidine ammonia-lyase
KR75_RS15105	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
KR75_RS15110	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
KR75_RS15110	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
KR75_RS15125	COG1349	DNA-binding transcription factor activity
KR75_RS15135	COG0023	Translation Initiation Factor
KR75_RS15145	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
KR75_RS15150	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
KR75_RS15155	COG0671	phosphoesterase, PA-phosphatase related
KR75_RS15165	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
KR75_RS15185	COG0616	signal peptide processing
KR75_RS15190	COG1028	Short-chain dehydrogenase reductase Sdr
KR75_RS15195	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
KR75_RS15210	COG0009	L-threonylcarbamoyladenylate synthase
KR75_RS15220	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
KR75_RS15225	COG0512	Glutamine amidotransferase of anthranilate synthase
KR75_RS15225	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
KR75_RS15230	COG0135	phosphoribosylanthranilate isomerase activity
KR75_RS15230	COG0134	indole-3-glycerol-phosphate synthase activity
KR75_RS15275	COG4774	siderophore transport
KR75_RS15285	COG3047	cAMP biosynthetic process
KR75_RS15290	COG0727	PFAM Uncharacterised protein family (UPF0153)
KR75_RS15320	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
KR75_RS15325	COG1028	Short-chain dehydrogenase reductase Sdr
KR75_RS15330	COG1988	membrane-bound metal-dependent
KR75_RS15335	COG1823	symporter activity
KR75_RS15345	COG0753	catalase activity
KR75_RS15355	COG1486	melibiose metabolic process
KR75_RS15360	COG2169	Transcriptional regulator
KR75_RS15360	COG1917	Cupin 2, conserved barrel domain protein
KR75_RS15365	COG1447	Phosphotransferase system cellobiose-specific component IIA
KR75_RS15370	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
KR75_RS15375	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
KR75_RS15380	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
KR75_RS15390	COG0322	excinuclease ABC activity
KR75_RS15395	COG3678	ATP-independent chaperone mediated protein folding
KR75_RS15405	COG3724	N-succinylarginine dihydrolase activity
KR75_RS15415	COG3138	arginine N-succinyltransferase
KR75_RS15425	COG0708	Exodeoxyribonuclease III
KR75_RS15430	COG0398	Pfam SNARE associated Golgi protein
KR75_RS15435	COG0398	Pfam SNARE associated Golgi protein
KR75_RS15440	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
KR75_RS15445	COG4134	Bacterial extracellular solute-binding protein
KR75_RS15450	COG4135	transport system, permease component
KR75_RS15455	COG4136	ATPase activity
KR75_RS15460	COG2897	thiosulfate sulfurtransferase activity
KR75_RS15465	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
KR75_RS15470	COG0494	nUDIX hydrolase
KR75_RS15475	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
KR75_RS15480	COG1028	Short-chain dehydrogenase reductase Sdr
KR75_RS15480	COG0604	alcohol dehydrogenase
KR75_RS15480	COG3321	synthase
KR75_RS15485	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KR75_RS15490	COG0709	Synthesizes selenophosphate from selenide and ATP
KR75_RS15500	COG0778	Nitroreductase
KR75_RS15505	COG0616	signal peptide processing
KR75_RS15510	COG0252	asparaginase activity
KR75_RS15515	COG1335	isochorismatase
KR75_RS15530	COG3139	Protein of unknown function (DUF1315)
KR75_RS15550	COG0656	L-ascorbic acid biosynthetic process
KR75_RS15555	COG3713	MltA-interacting MipA family protein
KR75_RS15560	COG2766	serine protein kinase
KR75_RS15575	COG0386	Belongs to the glutathione peroxidase family
KR75_RS15610	COG1126	abc transporter atp-binding protein
KR75_RS15615	COG0765	amino acid transport
KR75_RS15620	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KR75_RS15630	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
KR75_RS15645	COG0300	oxidoreductase activity
KR75_RS15650	COG0583	DNA-binding transcription factor activity
KR75_RS15655	COG1902	pentaerythritol trinitrate reductase activity
KR75_RS15665	COG1028	Short-chain dehydrogenase reductase Sdr
KR75_RS15670	COG0583	DNA-binding transcription factor activity
KR75_RS15685	COG1283	sodium-dependent phosphate transmembrane transporter activity
KR75_RS15720	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KR75_RS15725	COG0765	amino acid transport
KR75_RS15730	COG1126	abc transporter atp-binding protein
KR75_RS15735	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KR75_RS15740	COG4948	Mandelate Racemase Muconate Lactonizing
KR75_RS15745	COG0006	proline dipeptidase activity
KR75_RS15750	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KR75_RS15755	COG0504	CTP synthase activity
KR75_RS15760	COG0436	Aminotransferase
KR75_RS15775	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
KR75_RS15795	COG0859	PFAM glycosyl transferase family 9
KR75_RS15800	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
KR75_RS15810	COG2207	Transcriptional regulator
KR75_RS15815	COG2807	transmembrane transport
KR75_RS15820	COG0504	CTP synthase activity
KR75_RS15825	COG1683	Conserved Protein
KR75_RS15830	COG3189	MarR family transcriptional regulator
KR75_RS15835	COG3042	response to heat
KR75_RS15840	COG2203	Gaf domain
KR75_RS15840	COG2199	diguanylate cyclase activity
KR75_RS15845	COG3182	Iron-regulated membrane protein
KR75_RS15855	COG1560	Kdo2-lipid A biosynthetic process
KR75_RS15865	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
KR75_RS15870	COG3706	GGDEF domain
KR75_RS15875	COG0583	DNA-binding transcription factor activity
KR75_RS15880	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
KR75_RS15905	COG2207	Transcriptional regulator
KR75_RS15920	COG1566	PFAM secretion protein HlyD family protein
KR75_RS15925	COG1294	oxidase, subunit
KR75_RS15930	COG1271	oxidase subunit
KR75_RS15935	COG3546	catalase activity
KR75_RS15940	COG3685	Protein conserved in bacteria
KR75_RS15945	COG3685	Protein conserved in bacteria
KR75_RS15950	COG3729	General stress protein
KR75_RS15955	COG1063	alcohol dehydrogenase
KR75_RS15960	COG3813	Protein conserved in bacteria
KR75_RS15990	COG0640	Transcriptional regulator
KR75_RS16005	COG4943	cyclic-guanylate-specific phosphodiesterase activity
KR75_RS16010	COG3706	GGDEF domain
KR75_RS16085	COG3772	lysozyme
KR75_RS16100	COG1403	HNH endonuclease
KR75_RS16140	COG1396	sequence-specific DNA binding
KR75_RS16165	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
KR75_RS16175	COG0582	viral genome integration into host DNA
KR75_RS16180	COG0538	isocitrate dehydrogenase activity
KR75_RS16185	COG1187	pseudouridine synthase activity
KR75_RS16205	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
KR75_RS16225	COG2205	protein histidine kinase activity
KR75_RS16230	COG2850	peptidyl-arginine hydroxylation
KR75_RS16250	COG1177	transmembrane transport
KR75_RS16265	COG0318	PFAM AMP-dependent synthetase and ligase
KR75_RS16275	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
KR75_RS16285	COG4591	ABC-type transport system involved in lipoprotein release permease component
KR75_RS16295	COG4591	ABC-type transport system involved in lipoprotein release permease component
KR75_RS16300	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
KR75_RS16305	COG1388	LysM domain
KR75_RS16305	COG1376	ErfK ybiS ycfS ynhG family protein
KR75_RS16315	COG1309	transcriptional regulator
KR75_RS16325	COG3134	Outer membrane lipoprotein
KR75_RS16330	COG1252	NADH dehydrogenase
KR75_RS16355	COG5633	Lipoprotein
KR75_RS16360	COG0537	adenosine 5'-monophosphoramidase activity
KR75_RS16370	COG0084	hydrolase, TatD family'
KR75_RS16375	COG0470	DNA polymerase III
KR75_RS16385	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
KR75_RS16390	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
KR75_RS16395	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
KR75_RS16410	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
KR75_RS16430	COG1399	metal-binding, possibly nucleic acid-binding protein
KR75_RS16435	COG0424	maF-like protein
KR75_RS16445	COG1530	ribonuclease E activity
KR75_RS16450	COG0583	DNA-binding transcription factor activity
KR75_RS16455	COG2814	Major facilitator Superfamily
KR75_RS16475	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KR75_RS16520	COG1560	Kdo2-lipid A biosynthetic process
KR75_RS16535	COG5645	(Lipo)protein
KR75_RS16570	COG3381	protein complex oligomerization
KR75_RS16595	COG1309	transcriptional regulator
KR75_RS16600	COG0583	DNA-binding transcription factor activity
KR75_RS16610	COG1335	isochorismatase
KR75_RS16620	COG1702	phosphate starvation-inducible protein PhoH
KR75_RS16640	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KR75_RS16650	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KR75_RS16665	COG1309	transcriptional regulator
KR75_RS16700	COG2233	PERMEase
KR75_RS16735	COG1028	Short-chain dehydrogenase reductase Sdr
KR75_RS16745	COG0531	amino acid
KR75_RS16750	COG0174	glutamine synthetase
KR75_RS16755	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
KR75_RS16760	COG1396	sequence-specific DNA binding
KR75_RS16760	COG1917	Cupin 2, conserved barrel domain protein
KR75_RS16765	COG1012	belongs to the aldehyde dehydrogenase family
KR75_RS16770	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KR75_RS16775	COG0583	DNA-binding transcription factor activity
KR75_RS16780	COG0473	3-isopropylmalate dehydrogenase activity
KR75_RS16785	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
KR75_RS16790	COG4638	Rieske (2fe-2S)
KR75_RS16795	COG1012	belongs to the aldehyde dehydrogenase family
KR75_RS16800	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
KR75_RS16810	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KR75_RS16815	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KR75_RS16820	COG1882	Formate acetyltransferase
KR75_RS16825	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
KR75_RS16830	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KR75_RS16840	COG2207	Transcriptional regulator
KR75_RS16845	COG3706	GGDEF domain
KR75_RS16865	COG2200	EAL domain
KR75_RS16875	COG0058	SHG alpha-glucan phosphorylase activity
KR75_RS16890	COG0670	Belongs to the BI1 family
KR75_RS16905	COG2207	Transcriptional regulator
KR75_RS16910	COG1881	PFAM PEBP family protein
KR75_RS16925	COG1832	CoA-binding protein
KR75_RS16935	COG0210	DNA helicase
KR75_RS16940	COG3304	Inner membrane component domain
KR75_RS16945	COG1289	transmembrane transporter activity
KR75_RS16950	COG3070	regulator of competence-specific genes
KR75_RS16970	COG1067	ATP-dependent peptidase activity
KR75_RS16980	COG3009	Protein conserved in bacteria
KR75_RS16985	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
KR75_RS16985	COG3008	intermembrane lipid transfer
KR75_RS16990	COG2995	paraquat-inducible protein a
KR75_RS16995	COG0488	(ABC) transporter
KR75_RS17005	COG3217	Mosc domain protein beta barrel domain protein
KR75_RS17005	COG0633	Ferredoxin
KR75_RS17020	COG0431	NADPH-dependent FMN reductase
KR75_RS17025	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KR75_RS17030	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KR75_RS17035	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KR75_RS17045	COG0308	aminopeptidase N
KR75_RS17050	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
KR75_RS17065	COG0814	amino acid
KR75_RS17075	COG1522	sequence-specific DNA binding
KR75_RS17085	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
KR75_RS17090	COG1448	Aminotransferase
KR75_RS17095	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KR75_RS17100	COG3108	Peptidase M15
KR75_RS17105	COG2989	Protein conserved in bacteria
KR75_RS17115	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
KR75_RS17125	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
KR75_RS17130	COG1434	Gram-negative-bacterium-type cell wall biogenesis
KR75_RS17135	COG3173	Aminoglycoside phosphotransferase
KR75_RS17150	COG3214	Protein conserved in bacteria
KR75_RS17165	COG0658	competence protein
KR75_RS17165	COG2333	competence protein COMEC
KR75_RS17175	COG0539	negative regulation of cytoplasmic translation
KR75_RS17195	COG2323	membrane
KR75_RS17200	COG1944	ATP diphosphatase activity
KR75_RS17205	COG2116	formate transmembrane transporter activity
KR75_RS17210	COG1882	Formate acetyltransferase
KR75_RS17215	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
KR75_RS17220	COG0477	Major facilitator Superfamily
KR75_RS17225	COG3302	dmso reductase anchor subunit
KR75_RS17230	COG0437	4 iron, 4 sulfur cluster binding
KR75_RS17235	COG0243	molybdopterin cofactor binding
KR75_RS17245	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
KR75_RS17265	COG0492	ferredoxin-NADP+ reductase activity
KR75_RS17270	COG4988	ABC transporter
KR75_RS17275	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
KR75_RS17290	COG0542	response to heat
KR75_RS17300	COG1278	Cold shock
KR75_RS17310	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KR75_RS17315	COG3593	DNA synthesis involved in DNA repair
KR75_RS17325	COG2431	L-lysine efflux transmembrane transporter activity
KR75_RS17335	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
KR75_RS17345	COG0028	Belongs to the TPP enzyme family
KR75_RS17350	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
KR75_RS17355	COG0702	epimerase
KR75_RS17360	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KR75_RS17365	COG3023	N-Acetylmuramoyl-L-alanine amidase
KR75_RS17370	COG4251	negative regulation of phosphorylation
KR75_RS17370	COG3706	GGDEF domain
KR75_RS17370	COG5001	Diguanylate cyclase
KR75_RS17370	COG2203	Gaf domain
KR75_RS17385	COG1126	abc transporter atp-binding protein
KR75_RS17390	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KR75_RS17395	COG4215	(ABC) transporter
KR75_RS17400	COG4160	amino acid transport
KR75_RS17405	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KR75_RS17410	COG5002	protein histidine kinase activity
KR75_RS17415	COG0745	RESPONSE REGULATOR receiver
KR75_RS17430	COG1177	transmembrane transport
KR75_RS17435	COG1176	ABC-type spermidine putrescine transport system, permease component I
KR75_RS17440	COG3842	ATPase activity
KR75_RS17445	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
KR75_RS17460	COG0778	Nitroreductase
KR75_RS17600	COG4695	Portal protein
KR75_RS17655	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
KR75_RS17660	COG3226	Transcriptional regulator
KR75_RS17665	COG0738	Major facilitator superfamily
KR75_RS17670	COG0561	phosphatase activity
KR75_RS17675	COG2814	Major facilitator Superfamily
KR75_RS17680	COG0671	phosphoesterase, PA-phosphatase related
KR75_RS17685	COG1349	DNA-binding transcription factor activity
KR75_RS17690	COG1686	Belongs to the peptidase S11 family
KR75_RS17695	COG0625	glutathione transferase activity
KR75_RS17700	COG2133	pyrroloquinoline quinone binding
KR75_RS17710	COG2223	nitrite transmembrane transporter activity
KR75_RS17735	COG0747	negative chemotaxis
KR75_RS17745	COG1446	asparaginase
KR75_RS17750	COG0303	'Molybdopterin
KR75_RS17755	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
KR75_RS17760	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
KR75_RS17765	COG1882	Formate acetyltransferase
KR75_RS17770	COG0561	phosphatase activity
KR75_RS17780	COG1609	Transcriptional regulator
KR75_RS17785	COG2271	Major facilitator Superfamily
KR75_RS17795	COG0488	(ABC) transporter
KR75_RS17805	COG1376	ErfK ybiS ycfS ynhG family protein
KR75_RS17810	COG2188	Transcriptional regulator
KR75_RS17815	COG2723	6-phospho-beta-galactosidase activity
KR75_RS17820	COG0667	Aldo Keto reductase
KR75_RS17825	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
KR75_RS17840	COG2194	sulfuric ester hydrolase activity
KR75_RS17845	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
KR75_RS17860	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KR75_RS17865	COG0765	amino acid transport
KR75_RS17870	COG1126	abc transporter atp-binding protein
KR75_RS17875	COG0668	transmembrane transport
KR75_RS17885	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
KR75_RS17895	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
KR75_RS17905	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
KR75_RS17910	COG1199	ATP-dependent helicase activity
KR75_RS17915	COG0513	Belongs to the DEAD box helicase family
KR75_RS17920	COG3958	Transketolase
KR75_RS17925	COG3959	Transketolase, thiamine diphosphate binding domain
KR75_RS17930	COG1028	Short-chain dehydrogenase reductase Sdr
KR75_RS17935	COG2271	Major facilitator Superfamily
KR75_RS17940	COG0583	DNA-binding transcription factor activity
KR75_RS17945	COG1309	transcriptional regulator
KR75_RS17950	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KR75_RS17955	COG1131	(ABC) transporter
KR75_RS17960	COG0842	Transport permease protein
KR75_RS17965	COG0842	Transport permease protein
KR75_RS17975	COG3568	Endonuclease Exonuclease Phosphatase
KR75_RS17980	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KR75_RS17985	COG0392	lysyltransferase activity
KR75_RS17990	COG0670	Belongs to the BI1 family
KR75_RS17995	COG0314	molybdopterin synthase activity
KR75_RS18000	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
KR75_RS18010	COG0521	Mo-molybdopterin cofactor biosynthetic process
KR75_RS18055	COG2226	methyltransferase
KR75_RS18070	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
KR75_RS18075	COG1881	PFAM PEBP family protein
KR75_RS18110	COG4677	pectinesterase activity
KR75_RS18120	COG0589	response to stress
KR75_RS18125	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KR75_RS18160	COG0789	Transcriptional regulator
KR75_RS18165	COG2200	EAL domain
KR75_RS18190	COG0561	phosphatase activity
KR75_RS18200	COG4149	molybdate abc transporter
KR75_RS18205	COG0725	ABC transporter, periplasmic molybdate-binding protein
KR75_RS18215	COG2005	Transcriptional regulator
KR75_RS18215	COG3585	molybdate ion transport
KR75_RS18220	COG1119	ATPase activity
KR75_RS18230	COG1085	galactose-1-phosphate uridylyltransferase
KR75_RS18240	COG2017	converts alpha-aldose to the beta-anomer
KR75_RS18250	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
KR75_RS18260	COG1230	cation diffusion facilitator family transporter
KR75_RS18265	COG3201	nicotinamide mononucleotide transporter
KR75_RS18270	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
KR75_RS18325	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
KR75_RS18330	COG2885	chlorophyll binding
KR75_RS18340	COG3064	Membrane
KR75_RS18340	COG3064	Membrane
KR75_RS18345	COG0848	biopolymer transport protein
KR75_RS18350	COG0811	peptide transport
KR75_RS18355	COG0824	Thioesterase
KR75_RS18360	COG3790	cyd operon protein YbgE
KR75_RS18365	COG4890	Cyd operon protein YbgT
KR75_RS18370	COG1294	oxidase, subunit
KR75_RS18375	COG1271	oxidase subunit
KR75_RS18380	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
KR75_RS18390	COG0508	dehydrogenase complex catalyzes the overall conversion of
KR75_RS18395	COG0567	Dehydrogenase, E1 component
KR75_RS18400	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
KR75_RS18405	COG1053	succinate dehydrogenase
KR75_RS18410	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
KR75_RS18415	COG2009	succinate dehydrogenase
KR75_RS18440	COG1984	allophanate hydrolase subunit 2
KR75_RS18445	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
KR75_RS18485	COG2205	protein histidine kinase activity
KR75_RS18490	COG0745	RESPONSE REGULATOR receiver
KR75_RS18500	COG0033	Phosphoglucomutase
KR75_RS18510	COG0596	Alpha beta hydrolase
KR75_RS18525	COG0735	belongs to the Fur family
KR75_RS18530	COG0583	DNA-binding transcription factor activity
KR75_RS18535	COG1053	succinate dehydrogenase
KR75_RS18575	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
KR75_RS18580	COG1846	Transcriptional regulator
KR75_RS18580	COG1940	carbohydrate kinase activity
KR75_RS18585	COG0647	UMP catabolic process
KR75_RS18590	COG0367	asparagine synthase
KR75_RS18630	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KR75_RS18640	COG1702	phosphate starvation-inducible protein PhoH
KR75_RS18665	COG0765	amino acid transport
KR75_RS18670	COG0765	amino acid transport
KR75_RS18675	COG1126	abc transporter atp-binding protein
KR75_RS18690	COG2888	peptidyl-tyrosine sulfation
KR75_RS18705	COG1466	dna polymerase III delta subunit
KR75_RS18720	COG0799	negative regulation of ribosome biogenesis
KR75_RS18730	COG0768	penicillin binding
KR75_RS18735	COG0772	Belongs to the SEDS family
KR75_RS18740	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
KR75_RS18745	COG1686	Belongs to the peptidase S11 family
KR75_RS18760	COG0583	DNA-binding transcription factor activity
KR75_RS18770	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
KR75_RS18775	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
KR75_RS18795	COG3069	C4-dicarboxylate transmembrane transporter activity
KR75_RS18800	COG3719	Belongs to the RNase T2 family
KR75_RS18805	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
KR75_RS18825	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
KR75_RS18830	COG0583	DNA-binding transcription factor activity
KR75_RS18835	COG3969	phosphoadenosine phosphosulfate
KR75_RS18840	COG1475	DNA binding
KR75_RS18845	COG0436	Aminotransferase
KR75_RS18870	COG1129	ABC transporter
KR75_RS18875	COG1172	Belongs to the binding-protein-dependent transport system permease family
KR75_RS18880	COG1172	Belongs to the binding-protein-dependent transport system permease family
KR75_RS18890	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
KR75_RS18905	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
KR75_RS18915	COG0402	S-adenosylhomocysteine deaminase activity
KR75_RS18925	COG0483	inositol monophosphate 1-phosphatase activity
KR75_RS18930	COG2271	Major facilitator Superfamily
KR75_RS18960	COG1172	Belongs to the binding-protein-dependent transport system permease family
KR75_RS18965	COG1129	ABC transporter
KR75_RS18970	COG0371	Dehydrogenase
KR75_RS18990	COG2879	small protein
KR75_RS18995	COG1966	Carbon starvation protein
KR75_RS19010	COG1028	Short-chain dehydrogenase reductase Sdr
KR75_RS19015	COG3433	isochorismatase activity
KR75_RS19015	COG1535	isochorismatase
KR75_RS19020	COG1021	2,3-dihydroxybenzoate-AMP ligase
KR75_RS19025	COG1169	isochorismate synthase
KR75_RS19030	COG4592	Periplasmic binding protein
KR75_RS19040	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KR75_RS19045	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KR75_RS19050	COG1120	ATPase activity
KR75_RS19055	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
KR75_RS19055	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KR75_RS19060	COG3251	PFAM MbtH domain protein
KR75_RS19065	COG2382	esterase
KR75_RS19070	COG4771	TonB-dependent receptor
KR75_RS19075	COG2977	Belongs to the P-Pant transferase superfamily
KR75_RS19080	COG3958	Transketolase
KR75_RS19085	COG3959	Transketolase, thiamine diphosphate binding domain
KR75_RS19090	COG2390	Transcriptional regulator
KR75_RS19095	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
KR75_RS19100	COG1879	ABC-type sugar transport system periplasmic component
KR75_RS19110	COG1129	ABC transporter
KR75_RS19115	COG1172	Belongs to the binding-protein-dependent transport system permease family
KR75_RS19125	COG1028	Short-chain dehydrogenase reductase Sdr
KR75_RS19135	COG0583	DNA-binding transcription factor activity
KR75_RS19140	COG0668	transmembrane transport
KR75_RS19150	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
KR75_RS19195	COG0747	negative chemotaxis
KR75_RS19200	COG0601	transmembrane transport
KR75_RS19205	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KR75_RS19210	COG0444	Belongs to the ABC transporter superfamily
KR75_RS19215	COG4608	Belongs to the ABC transporter superfamily
KR75_RS19220	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
KR75_RS19225	COG4221	oxidoreductase activity
KR75_RS19235	COG4215	(ABC) transporter
KR75_RS19240	COG0765	amino acid transport
KR75_RS19245	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
KR75_RS19260	COG0697	spore germination
KR75_RS19275	COG4608	Belongs to the ABC transporter superfamily
KR75_RS19280	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KR75_RS19290	COG4166	transmembrane transport
KR75_RS19300	COG3698	Phosphodiester glycosidase
KR75_RS19340	COG2315	Protein conserved in bacteria
KR75_RS19345	COG0778	Nitroreductase
KR75_RS19355	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KR75_RS19365	COG3716	PTS system mannose fructose sorbose family IID component
KR75_RS19370	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
KR75_RS19375	COG2222	sugar isomerase
KR75_RS19380	COG3933	PFAM sigma-54 factor interaction domain-containing protein
KR75_RS19380	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
KR75_RS19400	COG0477	Major facilitator Superfamily
KR75_RS19405	COG0668	transmembrane transport
KR75_RS19410	COG1609	Transcriptional regulator
KR75_RS19420	COG0673	inositol 2-dehydrogenase activity
KR75_RS19430	COG2211	Major facilitator Superfamily
KR75_RS19435	COG1113	amino acid transport
KR75_RS19450	COG1012	belongs to the aldehyde dehydrogenase family
KR75_RS19455	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KR75_RS19465	COG0531	amino acid
KR75_RS19480	COG4680	protein conserved in bacteria
KR75_RS19510	COG0667	Aldo Keto reductase
KR75_RS19515	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KR75_RS19520	COG1473	amidohydrolase
KR75_RS19545	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KR75_RS19550	COG1120	ATPase activity
KR75_RS19555	COG1566	PFAM secretion protein HlyD family protein
KR75_RS19600	COG4211	Belongs to the binding-protein-dependent transport system permease family
KR75_RS19605	COG1129	ABC transporter
KR75_RS19620	COG0673	inositol 2-dehydrogenase activity
KR75_RS19655	COG3104	oligopeptide transport
KR75_RS19660	COG1982	Orn Lys Arg decarboxylase major
KR75_RS19665	COG0531	amino acid
KR75_RS19670	COG3710	Transcriptional regulator
KR75_RS19680	COG1560	Kdo2-lipid A biosynthetic process
KR75_RS19695	COG3188	usher protein
KR75_RS19700	COG3121	Chaperone
KR75_RS19705	COG3539	Fimbrial protein
KR75_RS19750	COG2501	S4 domain
KR75_RS19760	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
KR75_RS19775	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
KR75_RS19780	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
KR75_RS19795	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
KR75_RS19800	COG4181	ATPase activity
KR75_RS19805	COG2755	lipolytic protein G-D-S-L family
KR75_RS19810	COG0300	oxidoreductase activity
KR75_RS19815	COG3118	belongs to the thioredoxin family
KR75_RS19820	COG0390	transport system, permease component
KR75_RS19825	COG4619	ABC transporter
KR75_RS19830	COG0330	HflC and HflK could
KR75_RS19835	COG1585	Membrane protein implicated in regulation of membrane protease activity
KR75_RS19850	COG3735	TraB family
KR75_RS19855	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
KR75_RS19865	COG2223	nitrite transmembrane transporter activity
KR75_RS19870	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
KR75_RS19870	COG4651	solute:proton antiporter activity
KR75_RS19875	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KR75_RS19915	COG2832	Protein of unknown function (DUF454)
KR75_RS19920	COG3923	Primosomal replication protein n
KR75_RS19935	COG1196	nuclear chromosome segregation
KR75_RS19935	COG3264	Mechanosensitive ion channel
KR75_RS19940	COG1309	transcriptional regulator
KR75_RS19945	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KR75_RS19950	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KR75_RS19965	COG0110	maltose O-acetyltransferase activity
KR75_RS20010	COG1874	Beta-galactosidase
KR75_RS20015	COG3867	Arabinogalactan endo-beta-1,4-galactanase
KR75_RS20020	COG3833	ABC-type maltose transport systems, permease component
KR75_RS20025	COG1175	transmembrane transport
KR75_RS20030	COG2182	Extracellular solute-binding protein
KR75_RS20040	COG4943	cyclic-guanylate-specific phosphodiesterase activity
KR75_RS20055	COG2364	Membrane
KR75_RS20085	COG3695	enzyme binding
KR75_RS20090	COG3126	Type III secretion system lipoprotein chaperone (YscW)
KR75_RS20095	COG1946	Acyl-CoA thioesterase
KR75_RS20100	COG0004	ammonium transporteR
KR75_RS20105	COG0347	Belongs to the P(II) protein family
KR75_RS20110	COG1132	(ABC) transporter
KR75_RS20115	COG1132	(ABC) transporter
KR75_RS20120	COG1522	sequence-specific DNA binding
KR75_RS20135	COG4533	DNA binding
KR75_RS20145	COG0824	Thioesterase
KR75_RS20150	COG1555	photosystem II stabilization
KR75_RS20155	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
KR75_RS20160	COG0776	regulation of translation
KR75_RS20165	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
KR75_RS20185	COG0271	Belongs to the BolA IbaG family
KR75_RS20190	COG3056	Lipoprotein
KR75_RS20195	COG2223	nitrite transmembrane transporter activity
KR75_RS20200	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
KR75_RS20205	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
KR75_RS20210	COG1845	cytochrome c oxidase, subunit III
KR75_RS20215	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
KR75_RS20230	COG1414	Transcriptional regulator
KR75_RS20235	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
KR75_RS20240	COG1053	succinate dehydrogenase
KR75_RS20250	COG1053	succinate dehydrogenase
KR75_RS20265	COG0673	inositol 2-dehydrogenase activity
KR75_RS20270	COG2814	Major facilitator Superfamily
KR75_RS20280	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
KR75_RS20305	COG0142	geranyltranstransferase activity
KR75_RS20315	COG0667	Aldo Keto reductase
KR75_RS20320	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
KR75_RS20325	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
KR75_RS20340	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KR75_RS20340	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KR75_RS20350	COG4238	major outer membrane lipoprotein
KR75_RS20370	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
KR75_RS20375	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
KR75_RS20380	COG1862	Preprotein translocase
KR75_RS20400	COG0450	alkyl hydroperoxide reductase
KR75_RS20405	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
KR75_RS20420	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KR75_RS20430	COG1228	amidohydrolase
KR75_RS20440	COG1335	isochorismatase
KR75_RS20445	COG0583	DNA-binding transcription factor activity
KR75_RS20450	COG0366	Alpha amylase catalytic
KR75_RS20475	COG0420	3'-5' exonuclease activity
KR75_RS20480	COG0419	ATPase involved in DNA repair
KR75_RS20485	COG1940	carbohydrate kinase activity
KR75_RS20500	COG4126	flavin adenine dinucleotide binding
KR75_RS20510	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
KR75_RS20515	COG3416	Protein conserved in bacteria
KR75_RS20525	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KR75_RS20535	COG1785	Belongs to the alkaline phosphatase family
KR75_RS20555	COG1181	Belongs to the D-alanine--D-alanine ligase family
KR75_RS20575	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
KR75_RS20580	COG1335	isochorismatase
KR75_RS20585	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
KR75_RS20590	COG0113	porphobilinogen synthase activity
KR75_RS20605	COG2175	clavaminate synthase activity
KR75_RS20610	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KR75_RS20615	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
KR75_RS20620	COG4521	taurine ABC transporter
KR75_RS20625	COG2040	homocysteine
KR75_RS20630	COG0833	amino acid
KR75_RS20640	COG4303	Ethanolamine ammonia lyase large subunit
KR75_RS20645	COG4302	ethanolamine ammonia-lyase activity
KR75_RS20675	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KR75_RS20680	COG1126	abc transporter atp-binding protein
KR75_RS20685	COG4597	amino acid ABC transporter
KR75_RS20690	COG0765	amino acid transport
KR75_RS20705	COG3188	usher protein
KR75_RS20730	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
KR75_RS20740	COG3639	organic phosphonate transmembrane transporter activity
KR75_RS20755	COG0791	NLP P60 protein
KR75_RS20780	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KR75_RS20785	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KR75_RS20790	COG1116	anion transmembrane transporter activity
KR75_RS20810	COG2207	Transcriptional regulator
KR75_RS20820	COG0519	Catalyzes the synthesis of GMP from XMP
KR75_RS20820	COG0518	GMP synthase (glutamine-hydrolyzing) activity
KR75_RS20830	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
KR75_RS20835	COG0022	dehydrogenase e1 component
KR75_RS20840	COG0508	dehydrogenase complex catalyzes the overall conversion of
KR75_RS20845	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KR75_RS20855	COG0625	glutathione transferase activity
KR75_RS20860	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
KR75_RS20875	COG0579	oxidoreductase
KR75_RS20880	COG1012	belongs to the aldehyde dehydrogenase family
KR75_RS20885	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
KR75_RS20890	COG1113	amino acid transport
KR75_RS20895	COG1802	Transcriptional regulator
KR75_RS20915	COG2195	Cleaves the N-terminal amino acid of tripeptides
KR75_RS20920	COG0454	-acetyltransferase
KR75_RS20935	COG2991	Protein conserved in bacteria
KR75_RS20950	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
KR75_RS20955	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
KR75_RS20975	COG3034	peptidoglycan biosynthetic process
KR75_RS20980	COG0121	glutamine amidotransferase
KR75_RS20990	COG1960	acyl-CoA dehydrogenase activity
KR75_RS20995	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
KR75_RS21010	COG0583	DNA-binding transcription factor activity
KR75_RS21030	COG2226	methyltransferase
KR75_RS21040	COG1388	LysM domain
KR75_RS21040	COG0741	lytic transglycosylase activity
KR75_RS21045	COG2226	methyltransferase
KR75_RS21055	COG2814	Major facilitator Superfamily
KR75_RS21060	COG0583	DNA-binding transcription factor activity
KR75_RS21065	COG0656	L-ascorbic acid biosynthetic process
KR75_RS21100	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
KR75_RS21110	COG2011	ABC-type metal ion transport system permease component
KR75_RS21115	COG1464	Belongs to the NlpA lipoprotein family
KR75_RS21125	COG1720	tRNA m6t6A37 methyltransferase activity
KR75_RS21140	COG3015	lipoprotein NlpE involved in copper resistance
KR75_RS21145	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
KR75_RS21160	COG4568	rho-dependent transcription termination
KR75_RS21170	COG0346	lactoylglutathione lyase activity
KR75_RS21175	COG1982	Orn Lys Arg decarboxylase major
KR75_RS21215	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
KR75_RS21225	COG0750	zinc metalloprotease
KR75_RS21230	COG0575	Belongs to the CDS family
KR75_RS21265	COG0024	Methionine aminopeptidase
KR75_RS21270	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
KR75_RS21285	COG3835	regulator
KR75_RS21290	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KR75_RS21310	COG2860	membrane
KR75_RS21330	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KR75_RS21335	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KR75_RS21340	COG1120	ATPase activity
KR75_RS21345	COG4774	siderophore transport
KR75_RS21350	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KR75_RS21435	COG1643	Atp-dependent helicase
KR75_RS21440	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
KR75_RS21460	COG0617	tRNA 3'-terminal CCA addition
KR75_RS21465	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
KR75_RS21485	COG0726	polysaccharide deacetylase
KR75_RS21490	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
KR75_RS21495	COG0842	Transport permease protein
KR75_RS21500	COG1131	(ABC) transporter
KR75_RS21505	COG0288	reversible hydration of carbon dioxide
KR75_RS21515	COG4993	Dehydrogenase
KR75_RS21520	COG2132	Multicopper oxidase
KR75_RS21535	COG0545	Peptidyl-prolyl cis-trans isomerase
KR75_RS21560	COG3064	Membrane
KR75_RS21575	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KR75_RS21580	COG0508	dehydrogenase complex catalyzes the overall conversion of
KR75_RS21585	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
KR75_RS21590	COG2186	Transcriptional regulator
KR75_RS21595	COG1113	amino acid transport
KR75_RS21600	COG2211	Major facilitator Superfamily
KR75_RS21605	COG3940	Belongs to the glycosyl hydrolase 43 family
KR75_RS21610	COG3725	Membrane protein required for beta-lactamase induction
KR75_RS21615	COG3023	N-Acetylmuramoyl-L-alanine amidase
KR75_RS21625	COG4969	Belongs to the N-Me-Phe pilin family
KR75_RS21630	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
KR75_RS21635	COG1459	type II secretion system
KR75_RS21660	COG0494	nUDIX hydrolase
KR75_RS21680	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
KR75_RS21685	COG0849	cell division
KR75_RS21695	COG1181	Belongs to the D-alanine--D-alanine ligase family
KR75_RS21710	COG0772	Belongs to the SEDS family
KR75_RS21725	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
KR75_RS21735	COG0768	penicillin binding
KR75_RS21755	COG1609	Transcriptional regulator
KR75_RS21765	COG0028	Belongs to the TPP enzyme family
KR75_RS21800	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
KR75_RS21805	COG0738	Major facilitator superfamily
KR75_RS21815	COG0583	DNA-binding transcription factor activity
KR75_RS21820	COG2271	Major facilitator Superfamily
KR75_RS21825	COG2814	Major facilitator Superfamily
KR75_RS21840	COG1178	ABC-type Fe3 transport system permease component
KR75_RS21850	COG0586	Pfam SNARE associated Golgi protein
KR75_RS21870	COG0235	Class ii aldolase
KR75_RS21875	COG0417	DNA replication proofreading
KR75_RS21890	COG0564	pseudouridine synthase activity
KR75_RS21900	COG3493	citrate carrier protein
KR75_RS21915	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
KR75_RS21920	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
KR75_RS21930	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
KR75_RS21965	COG2271	Major facilitator Superfamily
KR75_RS21970	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KR75_RS21975	COG1609	Transcriptional regulator
KR75_RS21980	COG1028	Short-chain dehydrogenase reductase Sdr
KR75_RS21985	COG3265	gluconokinase activity
KR75_RS21990	COG2731	YhcH YjgK YiaL family protein
KR75_RS22005	COG0505	Belongs to the CarA family
KR75_RS22040	COG1047	Peptidyl-prolyl cis-trans
KR75_RS22055	COG0196	riboflavin kinase activity
KR75_RS22065	COG0583	DNA-binding transcription factor activity
KR75_RS22090	COG4735	regulation of single-species biofilm formation
KR75_RS22095	COG1584	GPR1 FUN34 yaaH family protein
KR75_RS22100	COG0477	Major facilitator Superfamily
KR75_RS22105	COG0521	Mo-molybdopterin cofactor biosynthetic process
KR75_RS22110	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
KR75_RS22115	COG1115	amino acid carrier protein
KR75_RS22130	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
KR75_RS22140	COG0460	homoserine dehydrogenase
KR75_RS22140	COG0527	aspartate kinase activity
KR75_RS22145	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
KR75_RS22150	COG0745	RESPONSE REGULATOR receiver
KR75_RS22155	COG4452	Inner membrane protein CreD
KR75_RS22160	COG2205	protein histidine kinase activity
KR75_RS22165	COG0745	RESPONSE REGULATOR receiver
KR75_RS22170	COG3045	CreA protein
KR75_RS22175	COG3708	Transcriptional regulator
KR75_RS22175	COG2207	Transcriptional regulator
KR75_RS22195	COG0741	lytic transglycosylase activity
KR75_RS22200	COG0488	(ABC) transporter
KR75_RS22210	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
KR75_RS22215	COG0560	Phosphoserine phosphatase
KR75_RS22220	COG3726	membrane protein affecting hemolysin expression
KR75_RS22250	COG0084	hydrolase, TatD family'
KR75_RS22255	COG4667	esterase of the alpha-beta hydrolase superfamily
KR75_RS22265	COG2823	Periplasmic or secreted lipoprotein
KR75_RS22275	COG1011	Hydrolase
KR75_RS22280	COG0456	acetyltransferase
KR75_RS22285	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
KR75_RS22315	COG3706	GGDEF domain
KR75_RS22320	COG4114	ferric iron reductase
KR75_RS22325	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
KR75_RS22330	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
KR75_RS22335	COG2197	response regulator
KR75_RS22340	COG2197	response regulator
KR75_RS22345	COG2169	Transcriptional regulator
KR75_RS22345	COG1917	Cupin 2, conserved barrel domain protein
KR75_RS22355	COG2966	Psort location CytoplasmicMembrane, score
KR75_RS22370	COG1484	DNA-dependent DNA replication
KR75_RS22395	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
KR75_RS22400	COG3716	PTS system mannose fructose sorbose family IID component
KR75_RS22405	COG3715	PTS system
KR75_RS22420	COG3933	PFAM sigma-54 factor interaction domain-containing protein
KR75_RS22420	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
KR75_RS22430	COG1063	alcohol dehydrogenase
KR75_RS22435	COG1802	Transcriptional regulator
KR75_RS22440	COG2271	Major facilitator Superfamily
KR75_RS22445	COG0456	acetyltransferase
KR75_RS22445	COG1214	PFAM Peptidase M22, glycoprotease
KR75_RS22460	COG0531	amino acid
KR75_RS22465	COG1012	belongs to the aldehyde dehydrogenase family
KR75_RS22470	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KR75_RS22485	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KR75_RS22485	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
KR75_RS22500	COG1846	Transcriptional regulator
KR75_RS22505	COG0179	Fumarylacetoacetate (FAA) hydrolase
KR75_RS22515	COG1012	belongs to the aldehyde dehydrogenase family
KR75_RS22520	COG3384	dioxygenase
KR75_RS22530	COG3971	2-oxopent-4-enoate hydratase activity
KR75_RS22550	COG2368	4-hydroxyphenylacetate
KR75_RS22555	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
KR75_RS22570	COG1966	Carbon starvation protein
KR75_RS22575	COG2879	small protein
KR75_RS22580	COG0523	cobalamin synthesis protein
KR75_RS22595	COG1012	belongs to the aldehyde dehydrogenase family
KR75_RS22600	COG5464	transposase or invertase
KR75_RS22605	COG2207	Transcriptional regulator
KR75_RS22605	COG1917	Cupin 2, conserved barrel domain protein
KR75_RS22615	COG2733	membrane
KR75_RS22630	COG1775	2-hydroxyglutaryl-CoA dehydratase, D-component
KR75_RS22635	COG1924	4 iron, 4 sulfur cluster binding
KR75_RS22645	COG1473	amidohydrolase
KR75_RS22650	COG0700	Nucleoside recognition
KR75_RS22655	COG3366	ferrous iron transmembrane transporter activity
KR75_RS22660	COG0583	DNA-binding transcription factor activity
KR75_RS22670	COG1566	PFAM secretion protein HlyD family protein
KR75_RS22680	COG5457	Domain of unknown function (DUF1127)
KR75_RS22685	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KR75_RS22695	COG0583	DNA-binding transcription factor activity
KR75_RS22700	COG2249	NAD(P)H dehydrogenase (quinone) activity
KR75_RS22710	COG1172	Belongs to the binding-protein-dependent transport system permease family
KR75_RS22715	COG1129	ABC transporter
KR75_RS22720	COG1879	ABC-type sugar transport system periplasmic component
KR75_RS22730	COG3706	GGDEF domain
KR75_RS22735	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KR75_RS22740	COG0842	Transport permease protein
KR75_RS22740	COG1129	ABC transporter
KR75_RS22745	COG0842	Transport permease protein
KR75_RS22785	COG2850	peptidyl-arginine hydroxylation
KR75_RS22790	COG5002	protein histidine kinase activity
KR75_RS22795	COG0745	RESPONSE REGULATOR receiver
KR75_RS22800	COG1538	Outer membrane efflux protein
KR75_RS22805	COG5569	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KR75_RS22810	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KR75_RS22815	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KR75_RS22825	COG3040	lipid binding
KR75_RS22830	COG0789	Transcriptional regulator
KR75_RS22835	COG3631	Ketosteroid isomerase-related protein
KR75_RS22840	COG0300	oxidoreductase activity
KR75_RS22855	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
KR75_RS22875	COG3272	Protein of unknown function (DUF1722)
KR75_RS22880	COG4580	involved in the transport of maltose and maltodextrins
KR75_RS22890	COG2211	Major facilitator Superfamily
KR75_RS22895	COG3507	Belongs to the glycosyl hydrolase 43 family
KR75_RS22965	COG0582	viral genome integration into host DNA
KR75_RS23030	COG0288	reversible hydration of carbon dioxide
KR75_RS23035	COG0659	secondary active sulfate transmembrane transporter activity
KR75_RS23040	COG1064	alcohol dehydrogenase
KR75_RS23045	COG1175	transmembrane transport
KR75_RS23050	COG0395	ABC-type sugar transport system, permease component
KR75_RS23055	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
KR75_RS23060	COG3842	ATPase activity
KR75_RS23065	COG1653	transport
KR75_RS23075	COG1082	Xylose isomerase domain protein TIM barrel
KR75_RS23085	COG3962	Belongs to the TPP enzyme family
KR75_RS23090	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KR75_RS23095	COG0837	glucose binding
KR75_RS23095	COG1737	Transcriptional regulator
KR75_RS23100	COG3718	enzyme involved in inositol metabolism
KR75_RS23115	COG0433	COG0433 Predicted ATPase
KR75_RS23120	COG0795	lipopolysaccharide-transporting ATPase activity
KR75_RS23125	COG0795	lipopolysaccharide-transporting ATPase activity
KR75_RS23135	COG2927	DNA polymerase III (CHI subunit)
KR75_RS23140	COG0525	valine-tRNA ligase activity
KR75_RS23165	COG2731	YhcH YjgK YiaL family protein
KR75_RS23195	COG1263	PTS System
KR75_RS23195	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KR75_RS23200	COG0366	Alpha amylase catalytic
KR75_RS23210	COG0602	queuosine metabolic process
KR75_RS23215	COG3711	transcriptional antiterminator
KR75_RS23215	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
KR75_RS23220	COG2706	6-phosphogluconolactonase activity
KR75_RS23235	COG3964	amidohydrolase
KR75_RS23270	COG0312	modulator of DNA gyrase
KR75_RS23290	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
KR75_RS23300	COG1172	Belongs to the binding-protein-dependent transport system permease family
KR75_RS23305	COG1172	Belongs to the binding-protein-dependent transport system permease family
KR75_RS23310	COG1129	ABC transporter
KR75_RS23315	COG1879	ABC-type sugar transport system periplasmic component
KR75_RS23330	COG2105	PFAM AIG2 family protein
KR75_RS23335	COG2911	Protein conserved in bacteria
KR75_RS23340	COG0729	surface antigen
KR75_RS23355	COG1914	H( )-stimulated, divalent metal cation uptake system
KR75_RS23360	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KR75_RS23365	COG1609	Transcriptional regulator
KR75_RS23370	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
KR75_RS23375	COG1253	flavin adenine dinucleotide binding
KR75_RS23400	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
KR75_RS23415	COG1733	regulation of RNA biosynthetic process
KR75_RS23420	COG0702	epimerase
KR75_RS23430	COG0697	spore germination
KR75_RS23440	COG1113	amino acid transport
KR75_RS23445	COG0545	Peptidyl-prolyl cis-trans isomerase
KR75_RS23450	COG3061	Opacity-associated protein A
KR75_RS23460	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
KR75_RS23465	COG2965	DNA replication, synthesis of RNA primer
KR75_RS23525	COG1073	alpha beta
KR75_RS23530	COG3650	response to hydrogen peroxide
KR75_RS23540	COG1960	acyl-CoA dehydrogenase activity
KR75_RS23545	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KR75_RS23550	COG0557	exoribonuclease II activity
KR75_RS23565	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
KR75_RS23575	COG0330	HflC and HflK could
KR75_RS23580	COG0330	HflC and HflK could
KR75_RS23585	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
KR75_RS23605	COG0860	N-Acetylmuramoyl-L-alanine amidase
KR75_RS23610	COG0802	atpase or kinase
KR75_RS23615	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
KR75_RS23615	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
KR75_RS23620	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
KR75_RS23640	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KR75_RS23660	COG1511	domain protein
KR75_RS23660	COG3264	Mechanosensitive ion channel
KR75_RS23675	COG1053	succinate dehydrogenase
KR75_RS23680	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
KR75_RS23700	COG2076	Multidrug Resistance protein
KR75_RS23720	COG1509	lysine 2,3-aminomutase activity
KR75_RS23785	COG0531	amino acid
KR75_RS23790	COG3030	protein affecting phage T7 exclusion by the F plasmid
KR75_RS23795	COG1027	Aspartate ammonia-lyase
KR75_RS23800	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
KR75_RS23815	COG1309	transcriptional regulator
KR75_RS23840	COG0457	Tetratricopeptide repeat
KR75_RS23845	COG0726	polysaccharide deacetylase
KR75_RS23845	COG1649	PFAM Uncharacterised BCR, COG1649
KR75_RS23850	COG1215	transferase activity, transferring glycosyl groups
KR75_RS23865	COG0861	Integral membrane protein TerC family
KR75_RS23895	COG1486	melibiose metabolic process
KR75_RS23900	COG2169	Transcriptional regulator
KR75_RS23910	COG2824	Alkylphosphonate utilization operon protein PhnA
KR75_RS23915	COG2764	glyoxalase bleomycin resistance protein dioxygenase
KR75_RS23920	COG2188	Transcriptional regulator
KR75_RS23925	COG3624	Phosphonate C-P lyase system protein PhnG
KR75_RS23930	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
KR75_RS23935	COG3626	phosphonate metabolism
KR75_RS23940	COG3627	carbon phosphorus lyase activity
KR75_RS23945	COG4107	phosphonate C-P lyase system protein PhnK
KR75_RS23950	COG4778	phosphonate C-P lyase system protein PhnL
KR75_RS23955	COG3454	Phosphonate metabolism
KR75_RS23965	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
KR75_RS23975	COG0784	Response regulator, receiver
KR75_RS23975	COG4191	Histidine kinase
KR75_RS23980	COG1129	ABC transporter
KR75_RS23985	COG1172	Belongs to the binding-protein-dependent transport system permease family
KR75_RS24015	COG3383	formate dehydrogenase (NAD+) activity
KR75_RS24020	COG3383	formate dehydrogenase (NAD+) activity
KR75_RS24025	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
KR75_RS24030	COG1301	dicarboxylic acid transport
KR75_RS24045	COG3162	membrane
KR75_RS24075	COG3539	Fimbrial protein
KR75_RS24080	COG1346	cytolysis
KR75_RS24085	COG1380	Effector of murein hydrolase LrgA
KR75_RS24090	COG0583	DNA-binding transcription factor activity
KR75_RS24095	COG0025	NhaP-type Na H and K H
KR75_RS24100	COG2252	PERMEase
KR75_RS24105	COG0625	glutathione transferase activity
KR75_RS24110	COG0789	Transcriptional regulator
KR75_RS24120	COG4943	cyclic-guanylate-specific phosphodiesterase activity
KR75_RS24145	COG3842	ATPase activity
KR75_RS24150	COG1234	tRNA 3'-trailer cleavage
KR75_RS24155	COG1609	Transcriptional regulator
KR75_RS24160	COG0483	inositol monophosphate 1-phosphatase activity
KR75_RS24170	COG0583	DNA-binding transcription factor activity
KR75_RS24180	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
KR75_RS24195	COG4771	TonB-dependent receptor
KR75_RS24200	COG0741	lytic transglycosylase activity
KR75_RS24205	COG0629	single-stranded DNA binding
KR75_RS24215	COG2315	Protein conserved in bacteria
KR75_RS24220	COG0432	Pfam Uncharacterised protein family UPF0047
KR75_RS24235	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
KR75_RS24240	COG0305	Participates in initiation and elongation during chromosome replication
KR75_RS24255	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KR75_RS24265	COG0735	belongs to the Fur family
KR75_RS24270	COG3237	CsbD-like
KR75_RS24275	COG0534	Mate efflux family protein
KR75_RS24285	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
KR75_RS24345	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
KR75_RS24355	COG0527	aspartate kinase activity
KR75_RS24420	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
KR75_RS24450	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
KR75_RS24460	COG0456	acetyltransferase
KR75_RS24495	COG0151	Belongs to the GarS family
KR75_RS24505	COG4191	Histidine kinase
KR75_RS24545	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
KR75_RS24560	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
KR75_RS24565	COG2104	thiamine diphosphate biosynthetic process
KR75_RS24575	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
KR75_RS24580	COG3706	GGDEF domain
KR75_RS24590	COG1447	Phosphotransferase system cellobiose-specific component IIA
KR75_RS24595	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
KR75_RS24630	COG0250	Participates in transcription elongation, termination and antitermination
KR75_RS24675	COG0812	UDP-N-acetylmuramate dehydrogenase activity
KR75_RS24710	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
KR75_RS24720	COG1739	Uncharacterized protein family UPF0029
KR75_RS24760	COG0805	protein transport
KR75_RS24780	COG3165	ubiquinone biosynthetic process from chorismate
KR75_RS24800	COG0412	Dienelactone hydrolase
KR75_RS24815	COG0583	DNA-binding transcription factor activity
KR75_RS24820	COG0697	spore germination
KR75_RS24825	COG0561	phosphatase activity
KR75_RS24830	COG2267	carboxylic ester hydrolase activity
KR75_RS24835	COG1280	lysine exporter protein (LysE YggA)
KR75_RS24845	COG1280	lysine exporter protein (LysE YggA)
KR75_RS24875	COG0210	DNA helicase
KR75_RS24880	COG1011	Hydrolase
KR75_RS24910	COG3072	Adenylate cyclase
KR75_RS24925	COG2959	enzyme of heme biosynthesis
KR75_RS24930	COG3071	HemY protein
KR75_RS24975	COG2244	polysaccharide biosynthetic process
KR75_RS24980	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
KR75_RS24985	COG0456	acetyltransferase
KR75_RS24990	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
KR75_RS24995	COG1088	dTDP-glucose 4,6-dehydratase activity
KR75_RS25000	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
KR75_RS25005	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
KR75_RS25015	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
KR75_RS25020	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
KR75_RS25025	COG3118	belongs to the thioredoxin family
KR75_RS25050	COG1811	Na channel or pump
KR75_RS25060	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
KR75_RS25065	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
KR75_RS25075	COG0583	DNA-binding transcription factor activity
KR75_RS25080	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
KR75_RS25090	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
KR75_RS25095	COG3978	acetolactate synthase activity
KR75_RS25110	COG3085	chromosome segregation
KR75_RS25185	COG0583	DNA-binding transcription factor activity
KR75_RS25200	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
KR75_RS25215	COG3443	Belongs to the bacterial solute-binding protein 9 family
KR75_RS25220	COG2207	Transcriptional regulator
KR75_RS25230	COG0371	Dehydrogenase
KR75_RS25240	COG0583	DNA-binding transcription factor activity
KR75_RS25250	COG0527	aspartate kinase activity
KR75_RS25250	COG0460	homoserine dehydrogenase
KR75_RS25255	COG0626	cystathionine gamma-synthase activity
KR75_RS25270	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
KR75_RS25275	COG1609	Transcriptional regulator
KR75_RS25280	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
KR75_RS25295	COG1575	Belongs to the MenA family. Type 1 subfamily
KR75_RS25315	COG3678	ATP-independent chaperone mediated protein folding
KR75_RS25320	COG0745	RESPONSE REGULATOR receiver
KR75_RS25325	COG2205	protein histidine kinase activity
KR75_RS25330	COG2258	MOSC domain
KR75_RS25335	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
KR75_RS25375	COG1129	ABC transporter
KR75_RS25380	COG1172	Belongs to the binding-protein-dependent transport system permease family
KR75_RS25385	COG1172	Belongs to the binding-protein-dependent transport system permease family
KR75_RS25390	COG1454	alcohol dehydrogenase
KR75_RS25405	COG2211	Major facilitator Superfamily
KR75_RS25410	COG1609	Transcriptional regulator
KR75_RS25415	COG2211	Major facilitator Superfamily
KR75_RS25475	COG0205	6-phosphofructokinase activity
KR75_RS25490	COG0243	molybdopterin cofactor binding
KR75_RS25490	COG3383	formate dehydrogenase (NAD+) activity
KR75_RS25495	COG3383	formate dehydrogenase (NAD+) activity
KR75_RS25495	COG0243	molybdopterin cofactor binding
KR75_RS25500	COG0437	4 iron, 4 sulfur cluster binding
KR75_RS25505	COG2864	formate dehydrogenase
KR75_RS25520	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
KR75_RS25525	COG0657	acetylesterase activity
KR75_RS25530	COG0456	acetyltransferase
KR75_RS25545	COG1011	Hydrolase
KR75_RS25560	COG3852	Histidine kinase
KR75_RS25570	COG0635	Involved in the biosynthesis of porphyrin-containing compound
KR75_RS25590	COG0204	Acyl-transferase
KR75_RS25600	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
KR75_RS25605	COG3084	Protein conserved in bacteria
KR75_RS25615	COG1763	Mo-molybdopterin cofactor biosynthetic process
KR75_RS25645	COG2186	Transcriptional regulator
KR75_RS25650	COG0477	Major facilitator Superfamily
KR75_RS25655	COG1609	Transcriptional regulator
KR75_RS25660	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KR75_RS25670	COG1172	Belongs to the binding-protein-dependent transport system permease family
KR75_RS25675	COG1129	ABC transporter
KR75_RS25705	COG1522	sequence-specific DNA binding
KR75_RS25710	COG0716	FMN binding
KR75_RS25725	COG3312	ion transport
KR75_RS25775	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
KR75_RS25780	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
KR75_RS25785	COG0573	inorganic phosphate transmembrane transporter activity
KR75_RS25790	COG0581	inorganic phosphate transmembrane transporter activity
KR75_RS25795	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
KR75_RS25800	COG0704	Plays a role in the regulation of phosphate uptake
KR75_RS25810	COG2382	esterase
KR75_RS25815	COG0363	glucosamine-6-phosphate deaminase activity
KR75_RS25820	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
KR75_RS25825	COG2252	PERMEase
KR75_RS25830	COG0431	NADPH-dependent FMN reductase
KR75_RS25835	COG2091	lysine biosynthetic process via aminoadipic acid
KR75_RS26185	COG2207	Transcriptional regulator
KR75_RS26230	COG1501	Belongs to the glycosyl hydrolase 31 family
KR75_RS26235	COG1501	Belongs to the glycosyl hydrolase 31 family