locus-tag	class	description
ISD32_RS00020	COG5455	response to cobalt ion
ISD32_RS00025	COG0583	DNA-binding transcription factor activity
ISD32_RS00030	COG2252	PERMEase
ISD32_RS00040	COG0583	DNA-binding transcription factor activity
ISD32_RS00130	COG0351	phosphomethylpyrimidine kinase
ISD32_RS00135	COG1830	Aldolase
ISD32_RS00150	COG1070	Carbohydrate kinase
ISD32_RS00160	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ISD32_RS00165	COG4948	Mandelate Racemase Muconate Lactonizing
ISD32_RS00170	COG0747	negative chemotaxis
ISD32_RS00175	COG0601	transmembrane transport
ISD32_RS00180	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ISD32_RS00185	COG0444	Belongs to the ABC transporter superfamily
ISD32_RS00190	COG4608	Belongs to the ABC transporter superfamily
ISD32_RS00200	COG4974	Belongs to the 'phage' integrase family
ISD32_RS00245	COG4695	Portal protein
ISD32_RS00395	COG0826	peptidase U32
ISD32_RS00400	COG0745	RESPONSE REGULATOR receiver
ISD32_RS00405	COG2205	protein histidine kinase activity
ISD32_RS00430	COG1301	dicarboxylic acid transport
ISD32_RS00450	COG5002	protein histidine kinase activity
ISD32_RS00455	COG0443	Heat shock 70 kDa protein
ISD32_RS00460	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
ISD32_RS00475	COG2982	Protein involved in outer membrane biogenesis
ISD32_RS00480	COG1253	flavin adenine dinucleotide binding
ISD32_RS00535	COG2244	polysaccharide biosynthetic process
ISD32_RS00555	COG1088	dTDP-glucose 4,6-dehydratase activity
ISD32_RS00590	COG1088	dTDP-glucose 4,6-dehydratase activity
ISD32_RS00620	COG0438	transferase activity, transferring glycosyl groups
ISD32_RS00620	COG1216	Glycosyl transferase, family 2
ISD32_RS00650	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
ISD32_RS00680	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ISD32_RS00685	COG0583	DNA-binding transcription factor activity
ISD32_RS00695	COG0531	amino acid
ISD32_RS00710	COG3604	Transcriptional regulator
ISD32_RS00715	COG2205	protein histidine kinase activity
ISD32_RS00800	COG0640	Transcriptional regulator
ISD32_RS00805	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
ISD32_RS00810	COG2925	Exonuclease
ISD32_RS00825	COG1289	transmembrane transporter activity
ISD32_RS00845	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
ISD32_RS00855	COG1942	4-Oxalocrotonate Tautomerase
ISD32_RS00860	COG0583	DNA-binding transcription factor activity
ISD32_RS00865	COG0095	Lipoate-protein ligase
ISD32_RS00870	COG0477	Major facilitator Superfamily
ISD32_RS00880	COG5001	Diguanylate cyclase
ISD32_RS00880	COG3300	MHYT domain
ISD32_RS00890	COG3615	Tellurite resistance protein tehB
ISD32_RS00915	COG3706	GGDEF domain
ISD32_RS00940	COG0534	Mate efflux family protein
ISD32_RS00950	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
ISD32_RS00970	COG0604	alcohol dehydrogenase
ISD32_RS00975	COG1309	transcriptional regulator
ISD32_RS00980	COG0025	NhaP-type Na H and K H
ISD32_RS00985	COG1045	serine acetyltransferase
ISD32_RS00990	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
ISD32_RS01010	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
ISD32_RS01015	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
ISD32_RS01050	COG0251	oxidation-reduction process
ISD32_RS01065	COG0765	amino acid transport
ISD32_RS01070	COG1126	abc transporter atp-binding protein
ISD32_RS01075	COG2079	MmgE PrpD family protein
ISD32_RS01080	COG1473	amidohydrolase
ISD32_RS01085	COG0456	acetyltransferase
ISD32_RS01090	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
ISD32_RS01095	COG0371	Dehydrogenase
ISD32_RS01100	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ISD32_RS01105	COG0436	Aminotransferase
ISD32_RS01125	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
ISD32_RS01135	COG1418	mRNA catabolic process
ISD32_RS01140	COG0270	DNA (cytosine-5-)-methyltransferase activity
ISD32_RS01145	COG3727	T/G mismatch-specific endonuclease activity
ISD32_RS01150	COG0697	spore germination
ISD32_RS01155	COG2354	Protein conserved in bacteria
ISD32_RS01185	COG0366	Alpha amylase catalytic
ISD32_RS01190	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ISD32_RS01200	COG0765	amino acid transport
ISD32_RS01205	COG1126	abc transporter atp-binding protein
ISD32_RS01210	COG2197	response regulator
ISD32_RS01220	COG2197	response regulator
ISD32_RS01260	COG3318	Belongs to the UPF0149 family
ISD32_RS01260	COG3012	SEC-C Motif Domain Protein
ISD32_RS01265	COG0814	amino acid
ISD32_RS01275	COG1528	Iron-storage protein
ISD32_RS01290	COG0477	Major facilitator Superfamily
ISD32_RS01300	COG2211	Major facilitator Superfamily
ISD32_RS01305	COG1528	Iron-storage protein
ISD32_RS01310	COG1879	ABC-type sugar transport system periplasmic component
ISD32_RS01320	COG1172	Belongs to the binding-protein-dependent transport system permease family
ISD32_RS01345	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
ISD32_RS01355	COG3102	Protein conserved in bacteria
ISD32_RS01375	COG3788	relative of glutathione S-transferase, MAPEG superfamily
ISD32_RS01380	COG1801	Protein of unknown function DUF72
ISD32_RS01385	COG1335	isochorismatase
ISD32_RS01395	COG0494	nUDIX hydrolase
ISD32_RS01420	COG1108	ABC-type Mn2 Zn2 transport systems permease components
ISD32_RS01430	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
ISD32_RS01435	COG0739	heme binding
ISD32_RS01440	COG1560	Kdo2-lipid A biosynthetic process
ISD32_RS01460	COG3493	citrate carrier protein
ISD32_RS01470	COG1737	Transcriptional regulator
ISD32_RS01480	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
ISD32_RS01485	COG0129	dihydroxy-acid dehydratase activity
ISD32_RS01490	COG0800	Aldolase
ISD32_RS01500	COG3141	response to X-ray
ISD32_RS01505	COG2979	Protein of unknown function (DUF533)
ISD32_RS01510	COG1770	oligopeptidase
ISD32_RS01515	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
ISD32_RS01525	COG2372	response to copper ion
ISD32_RS01530	COG1276	copper resistance
ISD32_RS01545	COG2990	Protein conserved in bacteria
ISD32_RS01570	COG3008	intermembrane lipid transfer
ISD32_RS01575	COG2995	paraquat-inducible protein a
ISD32_RS01580	COG1956	GAF domain-containing protein
ISD32_RS01600	COG2814	Major facilitator Superfamily
ISD32_RS01605	COG1414	Transcriptional regulator
ISD32_RS01640	COG0768	penicillin binding
ISD32_RS01645	COG2226	methyltransferase
ISD32_RS01660	COG3716	PTS system mannose fructose sorbose family IID component
ISD32_RS01665	COG3715	PTS system
ISD32_RS01670	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ISD32_RS01670	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
ISD32_RS01675	COG1253	flavin adenine dinucleotide binding
ISD32_RS01680	COG2200	EAL domain
ISD32_RS01685	COG1760	l-serine dehydratase
ISD32_RS01705	COG0251	oxidation-reduction process
ISD32_RS01710	COG1199	ATP-dependent helicase activity
ISD32_RS01720	COG3065	identical protein binding
ISD32_RS01730	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
ISD32_RS01740	COG2894	cell division
ISD32_RS01755	COG0179	Fumarylacetoacetate (FAA) hydrolase
ISD32_RS01785	COG2719	SpoVR family
ISD32_RS01810	COG1619	proteins homologs of microcin C7 resistance protein MccF
ISD32_RS01845	COG2308	Evidence 4 Homologs of previously reported genes of
ISD32_RS01865	COG3842	ATPase activity
ISD32_RS01870	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ISD32_RS01875	COG0395	ABC-type sugar transport system, permease component
ISD32_RS01890	COG1940	carbohydrate kinase activity
ISD32_RS01905	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ISD32_RS01915	COG1174	glycine betaine transport
ISD32_RS01935	COG0583	DNA-binding transcription factor activity
ISD32_RS01940	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
ISD32_RS01955	COG1882	Formate acetyltransferase
ISD32_RS01990	COG0583	DNA-binding transcription factor activity
ISD32_RS02020	COG0583	DNA-binding transcription factor activity
ISD32_RS02030	COG0564	pseudouridine synthase activity
ISD32_RS02035	COG3122	Protein conserved in bacteria
ISD32_RS02040	COG2186	Transcriptional regulator
ISD32_RS02045	COG3734	2-keto-3-deoxy-galactonokinase
ISD32_RS02050	COG0800	Aldolase
ISD32_RS02065	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
ISD32_RS02100	COG1388	LysM domain
ISD32_RS02160	COG0012	GTP binding
ISD32_RS02180	COG0659	secondary active sulfate transmembrane transporter activity
ISD32_RS02210	COG2890	protein-(glutamine-N5) methyltransferase activity
ISD32_RS02230	COG0387	Pfam Sodium calcium exchanger
ISD32_RS02235	COG4572	Cation transport regulator
ISD32_RS02240	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
ISD32_RS02250	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
ISD32_RS02255	COG3707	response regulator
ISD32_RS02260	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
ISD32_RS02270	COG1116	anion transmembrane transporter activity
ISD32_RS02275	COG2146	nitrite reductase [NAD(P)H] activity
ISD32_RS02275	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
ISD32_RS02280	COG0243	molybdopterin cofactor binding
ISD32_RS02285	COG4932	domain protein
ISD32_RS02290	COG2197	response regulator
ISD32_RS02295	COG3850	Histidine kinase
ISD32_RS02300	COG2223	nitrite transmembrane transporter activity
ISD32_RS02305	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
ISD32_RS02310	COG1140	nitrate reductase beta subunit
ISD32_RS02315	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
ISD32_RS02320	COG2181	nitrate reductase activity
ISD32_RS02330	COG1522	sequence-specific DNA binding
ISD32_RS02365	COG0788	formyltetrahydrofolate deformylase activity
ISD32_RS02375	COG1752	Esterase of the alpha-beta hydrolase superfamily
ISD32_RS02380	COG0745	RESPONSE REGULATOR receiver
ISD32_RS02385	COG1210	Utp--glucose-1-phosphate uridylyltransferase
ISD32_RS02390	COG2916	Histone family protein nucleoid-structuring protein H-NS
ISD32_RS02400	COG1435	thymidine kinase activity
ISD32_RS02405	COG1454	alcohol dehydrogenase
ISD32_RS02405	COG1012	belongs to the aldehyde dehydrogenase family
ISD32_RS02415	COG2095	MarC family integral membrane protein
ISD32_RS02420	COG4166	transmembrane transport
ISD32_RS02425	COG0601	transmembrane transport
ISD32_RS02430	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ISD32_RS02435	COG0444	Belongs to the ABC transporter superfamily
ISD32_RS02445	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
ISD32_RS02465	COG2353	YceI-like domain
ISD32_RS02470	COG4993	Dehydrogenase
ISD32_RS02475	COG2350	Protein conserved in bacteria
ISD32_RS02485	COG3001	Fructosamine kinase
ISD32_RS02495	COG1105	Belongs to the carbohydrate kinase PfkB family
ISD32_RS02500	COG3137	Salt-induced outer membrane protein
ISD32_RS02540	COG0072	phenylalanine-tRNA ligase activity
ISD32_RS02540	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ISD32_RS02550	COG0251	oxidation-reduction process
ISD32_RS02560	COG0583	DNA-binding transcription factor activity
ISD32_RS02580	COG0386	Belongs to the glutathione peroxidase family
ISD32_RS02590	COG0791	NLP P60 protein
ISD32_RS02600	COG4256	Hemin uptake protein
ISD32_RS02605	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
ISD32_RS02620	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
ISD32_RS02620	COG0574	Belongs to the PEP-utilizing enzyme family
ISD32_RS02630	COG0628	permease
ISD32_RS02635	COG0247	lactate metabolic process
ISD32_RS02635	COG0277	FAD linked oxidase domain protein
ISD32_RS02640	COG2050	protein possibly involved in aromatic compounds catabolism
ISD32_RS02645	COG2261	transglycosylase associated protein
ISD32_RS02670	COG1120	ATPase activity
ISD32_RS02675	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ISD32_RS02690	COG0583	DNA-binding transcription factor activity
ISD32_RS02715	COG1304	FMN binding
ISD32_RS02725	COG0316	Belongs to the HesB IscA family
ISD32_RS02730	COG0719	Fe-S assembly protein
ISD32_RS02735	COG0396	ATPase activity
ISD32_RS02740	COG0719	Fe-S assembly protein
ISD32_RS02755	COG1376	ErfK ybiS ycfS ynhG family protein
ISD32_RS02780	COG1309	transcriptional regulator
ISD32_RS02785	COG3185	4-Hydroxyphenylpyruvate dioxygenase
ISD32_RS02785	COG1082	Xylose isomerase domain protein TIM barrel
ISD32_RS02790	COG2271	Major facilitator Superfamily
ISD32_RS02795	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
ISD32_RS02805	COG1120	ATPase activity
ISD32_RS02810	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ISD32_RS02815	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
ISD32_RS02820	COG1414	Transcriptional regulator
ISD32_RS02855	COG2814	Major facilitator Superfamily
ISD32_RS02875	COG0583	DNA-binding transcription factor activity
ISD32_RS02880	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ISD32_RS02900	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ISD32_RS02905	COG1116	anion transmembrane transporter activity
ISD32_RS02910	COG4774	siderophore transport
ISD32_RS02915	COG1120	ATPase activity
ISD32_RS02920	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ISD32_RS02925	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ISD32_RS02945	COG0765	amino acid transport
ISD32_RS02950	COG1126	abc transporter atp-binding protein
ISD32_RS02985	COG3383	formate dehydrogenase (NAD+) activity
ISD32_RS02990	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
ISD32_RS03000	COG1175	transmembrane transport
ISD32_RS03035	COG4133	protoheme IX ABC transporter activity
ISD32_RS03040	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
ISD32_RS03045	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
ISD32_RS03060	COG1138	Cytochrome C-type biogenesis protein
ISD32_RS03065	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ISD32_RS03070	COG4235	cytochrome complex assembly
ISD32_RS03070	COG3088	subunit of a heme lyase
ISD32_RS03085	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
ISD32_RS03100	COG0583	DNA-binding transcription factor activity
ISD32_RS03130	COG1028	Short-chain dehydrogenase reductase Sdr
ISD32_RS03135	COG2610	gluconate transmembrane transporter activity
ISD32_RS03140	COG1250	3-hydroxyacyl-CoA dehydrogenase
ISD32_RS03150	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
ISD32_RS03160	COG0583	DNA-binding transcription factor activity
ISD32_RS03190	COG2814	Major facilitator Superfamily
ISD32_RS03210	COG0277	FAD linked oxidase domain protein
ISD32_RS03215	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ISD32_RS03240	COG0402	S-adenosylhomocysteine deaminase activity
ISD32_RS03275	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
ISD32_RS03285	COG1028	Short-chain dehydrogenase reductase Sdr
ISD32_RS03290	COG0531	amino acid
ISD32_RS03295	COG0583	DNA-binding transcription factor activity
ISD32_RS03320	COG4608	Belongs to the ABC transporter superfamily
ISD32_RS03325	COG0444	Belongs to the ABC transporter superfamily
ISD32_RS03355	COG2011	ABC-type metal ion transport system permease component
ISD32_RS03370	COG0346	lactoylglutathione lyase activity
ISD32_RS03375	COG1349	DNA-binding transcription factor activity
ISD32_RS03415	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ISD32_RS03435	COG0300	oxidoreductase activity
ISD32_RS03475	COG0307	riboflavin synthase, alpha
ISD32_RS03480	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
ISD32_RS03485	COG2814	Major facilitator Superfamily
ISD32_RS03490	COG0583	DNA-binding transcription factor activity
ISD32_RS03505	COG2814	Major facilitator Superfamily
ISD32_RS03515	COG2207	Transcriptional regulator
ISD32_RS03520	COG0791	NLP P60 protein
ISD32_RS03525	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
ISD32_RS03535	COG0346	lactoylglutathione lyase activity
ISD32_RS03540	COG1902	pentaerythritol trinitrate reductase activity
ISD32_RS03545	COG1309	transcriptional regulator
ISD32_RS03550	COG3313	Fe-S protein
ISD32_RS03555	COG4989	oxidoreductase activity
ISD32_RS03560	COG2032	superoxide dismutase activity
ISD32_RS03565	COG1289	transmembrane transporter activity
ISD32_RS03570	COG1566	PFAM secretion protein HlyD family protein
ISD32_RS03585	COG3706	GGDEF domain
ISD32_RS03600	COG3895	Periplasmic Protein
ISD32_RS03615	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
ISD32_RS03620	COG0625	glutathione transferase activity
ISD32_RS03630	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
ISD32_RS03640	COG4659	FMN binding
ISD32_RS03675	COG2723	6-phospho-beta-galactosidase activity
ISD32_RS03685	COG0673	inositol 2-dehydrogenase activity
ISD32_RS03695	COG2814	Major facilitator Superfamily
ISD32_RS03715	COG3038	cytochrome b561
ISD32_RS03735	COG0583	DNA-binding transcription factor activity
ISD32_RS03740	COG3485	protocatechuate 3,4-dioxygenase
ISD32_RS03745	COG3485	protocatechuate 3,4-dioxygenase
ISD32_RS03750	COG5383	Protein conserved in bacteria
ISD32_RS03755	COG2272	Belongs to the type-B carboxylesterase lipase family
ISD32_RS03770	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
ISD32_RS03775	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
ISD32_RS03780	COG1275	C4-dicarboxylate transporter malic acid transport protein
ISD32_RS03785	COG0500	methyltransferase
ISD32_RS03800	COG3708	Transcriptional regulator
ISD32_RS03800	COG2207	Transcriptional regulator
ISD32_RS03805	COG3135	benzoate transporter
ISD32_RS03810	COG1396	sequence-specific DNA binding
ISD32_RS03820	COG0826	peptidase U32
ISD32_RS03840	COG1294	oxidase, subunit
ISD32_RS03845	COG1271	oxidase subunit
ISD32_RS03850	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ISD32_RS03855	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
ISD32_RS03860	COG3842	ATPase activity
ISD32_RS03865	COG1176	ABC-type spermidine putrescine transport system, permease component I
ISD32_RS03870	COG1177	transmembrane transport
ISD32_RS03875	COG1012	belongs to the aldehyde dehydrogenase family
ISD32_RS03905	COG1012	belongs to the aldehyde dehydrogenase family
ISD32_RS03910	COG0747	negative chemotaxis
ISD32_RS03920	COG3238	Protein conserved in bacteria
ISD32_RS03925	COG1247	-acetyltransferase
ISD32_RS03935	COG2130	NADP-dependent
ISD32_RS03950	COG3691	Protein conserved in bacteria
ISD32_RS03955	COG4772	TonB-dependent receptor
ISD32_RS03980	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
ISD32_RS03985	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
ISD32_RS03990	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
ISD32_RS03995	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ISD32_RS04000	COG1473	amidohydrolase
ISD32_RS04005	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ISD32_RS04010	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ISD32_RS04020	COG0765	amino acid transport
ISD32_RS04025	COG1126	abc transporter atp-binding protein
ISD32_RS04035	COG2271	Major facilitator Superfamily
ISD32_RS04045	COG1609	Transcriptional regulator
ISD32_RS04050	COG0625	glutathione transferase activity
ISD32_RS04080	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
ISD32_RS04085	COG3842	ATPase activity
ISD32_RS04090	COG1840	ABC-type Fe3 transport system, periplasmic component
ISD32_RS04095	COG1178	ABC-type Fe3 transport system permease component
ISD32_RS04100	COG2162	N-hydroxyarylamine O-acetyltransferase activity
ISD32_RS04105	COG2181	nitrate reductase activity
ISD32_RS04110	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
ISD32_RS04115	COG1140	nitrate reductase beta subunit
ISD32_RS04120	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
ISD32_RS04140	COG1414	Transcriptional regulator
ISD32_RS04145	COG4948	Mandelate Racemase Muconate Lactonizing
ISD32_RS04150	COG4829	muconolactone delta-isomerase
ISD32_RS04155	COG3485	protocatechuate 3,4-dioxygenase
ISD32_RS04190	COG0437	4 iron, 4 sulfur cluster binding
ISD32_RS04195	COG2864	formate dehydrogenase
ISD32_RS04210	COG2326	polyphosphate kinase activity
ISD32_RS04220	COG2814	Major facilitator Superfamily
ISD32_RS04230	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ISD32_RS04240	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ISD32_RS04245	COG0601	transmembrane transport
ISD32_RS04250	COG0747	negative chemotaxis
ISD32_RS04255	COG1064	alcohol dehydrogenase
ISD32_RS04270	COG0488	(ABC) transporter
ISD32_RS04310	COG1028	Short-chain dehydrogenase reductase Sdr
ISD32_RS04315	COG3729	General stress protein
ISD32_RS04325	COG3685	Protein conserved in bacteria
ISD32_RS04335	COG0366	Alpha amylase catalytic
ISD32_RS04345	COG2323	membrane
ISD32_RS04355	COG3111	PFAM Bacterial OB fold (BOF) protein
ISD32_RS04365	COG1764	response to oxidative stress
ISD32_RS04380	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
ISD32_RS04385	COG3781	membrane
ISD32_RS04390	COG0243	molybdopterin cofactor binding
ISD32_RS04395	COG0583	DNA-binding transcription factor activity
ISD32_RS04400	COG2814	Major facilitator Superfamily
ISD32_RS04405	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
ISD32_RS04425	COG0519	Catalyzes the synthesis of GMP from XMP
ISD32_RS04425	COG0518	GMP synthase (glutamine-hydrolyzing) activity
ISD32_RS04465	COG0596	Alpha beta hydrolase
ISD32_RS04475	COG2205	protein histidine kinase activity
ISD32_RS04490	COG0076	glutamate decarboxylase activity
ISD32_RS04495	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
ISD32_RS04500	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
ISD32_RS04505	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ISD32_RS04510	COG1116	anion transmembrane transporter activity
ISD32_RS04515	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
ISD32_RS04535	COG0673	inositol 2-dehydrogenase activity
ISD32_RS04545	COG1609	Transcriptional regulator
ISD32_RS04550	COG3706	GGDEF domain
ISD32_RS04560	COG0402	S-adenosylhomocysteine deaminase activity
ISD32_RS04565	COG1953	Uracil, thiamine, allantoin
ISD32_RS04620	COG2207	Transcriptional regulator
ISD32_RS04635	COG0583	DNA-binding transcription factor activity
ISD32_RS04655	COG1263	PTS System
ISD32_RS04655	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ISD32_RS04655	COG2190	(PTS) system
ISD32_RS04660	COG2723	6-phospho-beta-galactosidase activity
ISD32_RS04665	COG3711	transcriptional antiterminator
ISD32_RS04670	COG0583	DNA-binding transcription factor activity
ISD32_RS04685	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
ISD32_RS04755	COG0765	amino acid transport
ISD32_RS04765	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
ISD32_RS04775	COG2070	2-Nitropropane dioxygenase
ISD32_RS04780	COG0583	DNA-binding transcription factor activity
ISD32_RS04790	COG1902	pentaerythritol trinitrate reductase activity
ISD32_RS04795	COG4529	Protein conserved in bacteria
ISD32_RS04800	COG0477	Major facilitator Superfamily
ISD32_RS04830	COG2223	nitrite transmembrane transporter activity
ISD32_RS04845	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
ISD32_RS04855	COG3665	Urea carboxylase-associated protein
ISD32_RS04860	COG0439	Biotin carboxylase
ISD32_RS04890	COG2197	response regulator
ISD32_RS04940	COG0583	DNA-binding transcription factor activity
ISD32_RS04945	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ISD32_RS04955	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
ISD32_RS04970	COG1172	Belongs to the binding-protein-dependent transport system permease family
ISD32_RS04980	COG1609	Transcriptional regulator
ISD32_RS05005	COG0747	negative chemotaxis
ISD32_RS05010	COG0601	transmembrane transport
ISD32_RS05015	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ISD32_RS05025	COG2814	Major facilitator Superfamily
ISD32_RS05030	COG1566	PFAM secretion protein HlyD family protein
ISD32_RS05075	COG4128	Pfam Zonular occludens toxin
ISD32_RS05100	COG5002	protein histidine kinase activity
ISD32_RS05100	COG3850	Histidine kinase
ISD32_RS05185	COG2186	Transcriptional regulator
ISD32_RS05190	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ISD32_RS05190	COG1263	PTS System
ISD32_RS05200	COG2814	Major facilitator Superfamily
ISD32_RS05205	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
ISD32_RS05205	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
ISD32_RS05220	COG2819	hydrolase of the alpha beta superfamily
ISD32_RS05225	COG3300	MHYT domain
ISD32_RS05225	COG5001	Diguanylate cyclase
ISD32_RS05245	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
ISD32_RS05280	COG3188	usher protein
ISD32_RS05290	COG1649	PFAM Uncharacterised BCR, COG1649
ISD32_RS05295	COG3550	peptidyl-serine autophosphorylation
ISD32_RS05300	COG1396	sequence-specific DNA binding
ISD32_RS05305	COG2351	hydroxyisourate hydrolase activity
ISD32_RS05315	COG2233	PERMEase
ISD32_RS05345	COG2207	Transcriptional regulator
ISD32_RS05360	COG4628	conserved protein (DUF2132)
ISD32_RS05380	COG2011	ABC-type metal ion transport system permease component
ISD32_RS05385	COG2070	2-Nitropropane dioxygenase
ISD32_RS05395	COG0477	Major facilitator Superfamily
ISD32_RS05470	COG2199	diguanylate cyclase activity
ISD32_RS05485	COG1012	belongs to the aldehyde dehydrogenase family
ISD32_RS05490	COG0583	DNA-binding transcription factor activity
ISD32_RS05500	COG0039	L-malate dehydrogenase activity
ISD32_RS05505	COG1349	DNA-binding transcription factor activity
ISD32_RS05510	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
ISD32_RS05515	COG3395	kinase activity
ISD32_RS05525	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ISD32_RS05530	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
ISD32_RS05535	COG2271	Major facilitator Superfamily
ISD32_RS05560	COG4977	sequence-specific DNA binding
ISD32_RS05570	COG0697	spore germination
ISD32_RS05575	COG2814	Major facilitator Superfamily
ISD32_RS05605	COG0683	leucine binding
ISD32_RS05610	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
ISD32_RS05645	COG2223	nitrite transmembrane transporter activity
ISD32_RS05650	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
ISD32_RS05665	COG1349	DNA-binding transcription factor activity
ISD32_RS05670	COG2084	Dehydrogenase
ISD32_RS05675	COG3395	kinase activity
ISD32_RS05680	COG0235	Class ii aldolase
ISD32_RS05685	COG3622	Belongs to the hyi family
ISD32_RS05690	COG2610	gluconate transmembrane transporter activity
ISD32_RS05695	COG2207	Transcriptional regulator
ISD32_RS05695	COG3708	Transcriptional regulator
ISD32_RS05710	COG2200	EAL domain
ISD32_RS05715	COG1546	Belongs to the CinA family
ISD32_RS05720	COG0071	Belongs to the small heat shock protein (HSP20) family
ISD32_RS05775	COG0583	DNA-binding transcription factor activity
ISD32_RS05785	COG0406	alpha-ribazole phosphatase activity
ISD32_RS05790	COG0583	DNA-binding transcription factor activity
ISD32_RS05815	COG3210	domain, Protein
ISD32_RS05875	COG1196	nuclear chromosome segregation
ISD32_RS05955	COG3728	DNA packaging
ISD32_RS05955	COG5484	DNA packaging
ISD32_RS06015	COG3477	response to acidic pH
ISD32_RS06055	COG0583	DNA-binding transcription factor activity
ISD32_RS06075	COG1484	DNA-dependent DNA replication
ISD32_RS06125	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
ISD32_RS06145	COG0582	viral genome integration into host DNA
ISD32_RS06155	COG4221	oxidoreductase activity
ISD32_RS06160	COG1802	Transcriptional regulator
ISD32_RS06165	COG0589	response to stress
ISD32_RS06170	COG0246	Mannitol dehydrogenase
ISD32_RS06175	COG2271	Major facilitator Superfamily
ISD32_RS06190	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
ISD32_RS06205	COG0243	molybdopterin cofactor binding
ISD32_RS06210	COG0437	4 iron, 4 sulfur cluster binding
ISD32_RS06215	COG3302	dmso reductase anchor subunit
ISD32_RS06230	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
ISD32_RS06235	COG1940	carbohydrate kinase activity
ISD32_RS06240	COG0583	DNA-binding transcription factor activity
ISD32_RS06245	COG2814	Major facilitator Superfamily
ISD32_RS06250	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
ISD32_RS06265	COG3591	Belongs to the peptidase S1B family
ISD32_RS06285	COG0628	permease
ISD32_RS06315	COG0679	Auxin Efflux Carrier
ISD32_RS06325	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
ISD32_RS06355	COG3290	protein histidine kinase activity
ISD32_RS06360	COG4565	transcriptional regulatory protein
ISD32_RS06380	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
ISD32_RS06380	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
ISD32_RS06390	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
ISD32_RS06395	COG0596	Alpha beta hydrolase
ISD32_RS06405	COG0183	Belongs to the thiolase family
ISD32_RS06410	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
ISD32_RS06420	COG1414	Transcriptional regulator
ISD32_RS06425	COG2840	Smr protein MutS2
ISD32_RS06430	COG0583	DNA-binding transcription factor activity
ISD32_RS06440	COG1473	amidohydrolase
ISD32_RS06445	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
ISD32_RS06460	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
ISD32_RS06475	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
ISD32_RS06480	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
ISD32_RS06495	COG0531	amino acid
ISD32_RS06505	COG3136	membrane protein required for alginate biosynthesis
ISD32_RS06510	COG0745	RESPONSE REGULATOR receiver
ISD32_RS06520	COG1028	Short-chain dehydrogenase reductase Sdr
ISD32_RS06525	COG2205	protein histidine kinase activity
ISD32_RS06535	COG0114	fumarate hydratase activity
ISD32_RS06540	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
ISD32_RS06540	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
ISD32_RS06545	COG1482	cell wall glycoprotein biosynthetic process
ISD32_RS06550	COG5339	Protein conserved in bacteria
ISD32_RS06555	COG1609	Transcriptional regulator
ISD32_RS06560	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ISD32_RS06560	COG1263	PTS System
ISD32_RS06565	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
ISD32_RS06595	COG0425	Belongs to the sulfur carrier protein TusA family
ISD32_RS06600	COG5562	phage envelope protein
ISD32_RS06605	COG0401	homolog of Blt101
ISD32_RS06610	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
ISD32_RS06615	COG1012	belongs to the aldehyde dehydrogenase family
ISD32_RS06625	COG1434	Gram-negative-bacterium-type cell wall biogenesis
ISD32_RS06630	COG0477	Major facilitator Superfamily
ISD32_RS06635	COG1113	amino acid transport
ISD32_RS06640	COG2988	succinylglutamate desuccinylase activity
ISD32_RS06645	COG3724	N-succinylarginine dihydrolase activity
ISD32_RS06650	COG1012	belongs to the aldehyde dehydrogenase family
ISD32_RS06655	COG3138	arginine N-succinyltransferase
ISD32_RS06660	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
ISD32_RS06670	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
ISD32_RS06685	COG0183	Belongs to the thiolase family
ISD32_RS06695	COG0667	Aldo Keto reductase
ISD32_RS06700	COG2814	Major facilitator Superfamily
ISD32_RS06705	COG0667	Aldo Keto reductase
ISD32_RS06710	COG0583	DNA-binding transcription factor activity
ISD32_RS06735	COG4122	O-methyltransferase activity
ISD32_RS06745	COG1643	Atp-dependent helicase
ISD32_RS06755	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system
ISD32_RS06765	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
ISD32_RS06770	COG3327	negative regulation of DNA-templated transcription, initiation
ISD32_RS06775	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
ISD32_RS06780	COG0183	Belongs to the thiolase family
ISD32_RS06785	COG2050	protein possibly involved in aromatic compounds catabolism
ISD32_RS06790	COG1250	3-hydroxyacyl-CoA dehydrogenase
ISD32_RS06795	COG1024	Enoyl-CoA hydratase
ISD32_RS06800	COG1024	Enoyl-CoA hydratase
ISD32_RS06805	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
ISD32_RS06810	COG2151	metal-sulfur cluster biosynthetic enzyme
ISD32_RS06815	COG3396	Phenylacetate-CoA oxygenase
ISD32_RS06820	COG3460	Phenylacetate-CoA oxygenase
ISD32_RS06825	COG3396	Phenylacetate-CoA oxygenase
ISD32_RS06830	COG1012	belongs to the aldehyde dehydrogenase family
ISD32_RS06830	COG2030	dehydratase
ISD32_RS06850	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
ISD32_RS06865	COG2072	flavoprotein involved in K transport
ISD32_RS06870	COG0583	DNA-binding transcription factor activity
ISD32_RS06875	COG1126	abc transporter atp-binding protein
ISD32_RS06885	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ISD32_RS06900	COG1012	belongs to the aldehyde dehydrogenase family
ISD32_RS06905	COG2207	Transcriptional regulator
ISD32_RS06910	COG3784	Protein of unknown function (DUF1318)
ISD32_RS06920	COG2911	Protein conserved in bacteria
ISD32_RS06925	COG0586	Pfam SNARE associated Golgi protein
ISD32_RS06930	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
ISD32_RS06935	COG3187	Heat shock protein
ISD32_RS06940	COG3042	response to heat
ISD32_RS06945	COG1013	pyruvate-flavodoxin oxidoreductase activity
ISD32_RS06945	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
ISD32_RS06945	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ISD32_RS06945	COG0674	pyruvate-flavodoxin oxidoreductase activity
ISD32_RS06950	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
ISD32_RS06960	COG0589	response to stress
ISD32_RS06970	COG0513	Belongs to the DEAD box helicase family
ISD32_RS06980	COG1349	DNA-binding transcription factor activity
ISD32_RS06985	COG0673	inositol 2-dehydrogenase activity
ISD32_RS07000	COG1113	amino acid transport
ISD32_RS07005	COG1522	sequence-specific DNA binding
ISD32_RS07015	COG1448	Aminotransferase
ISD32_RS07020	COG2011	ABC-type metal ion transport system permease component
ISD32_RS07030	COG1464	Belongs to the NlpA lipoprotein family
ISD32_RS07035	COG0436	Aminotransferase
ISD32_RS07040	COG0604	alcohol dehydrogenase
ISD32_RS07070	COG0583	DNA-binding transcription factor activity
ISD32_RS07090	COG1028	Short-chain dehydrogenase reductase Sdr
ISD32_RS07095	COG1309	transcriptional regulator
ISD32_RS07100	COG1028	Short-chain dehydrogenase reductase Sdr
ISD32_RS07190	COG2885	chlorophyll binding
ISD32_RS07215	COG0693	protein deglycase activity
ISD32_RS07220	COG1028	Short-chain dehydrogenase reductase Sdr
ISD32_RS07225	COG0583	DNA-binding transcription factor activity
ISD32_RS07290	COG3250	beta-galactosidase activity
ISD32_RS07295	COG0656	L-ascorbic acid biosynthetic process
ISD32_RS07340	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
ISD32_RS07345	COG0583	DNA-binding transcription factor activity
ISD32_RS07350	COG0583	DNA-binding transcription factor activity
ISD32_RS07355	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ISD32_RS07365	COG0765	amino acid transport
ISD32_RS07375	COG4166	transmembrane transport
ISD32_RS07385	COG2866	Carboxypeptidase
ISD32_RS07390	COG4948	Mandelate Racemase Muconate Lactonizing
ISD32_RS07395	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
ISD32_RS07400	COG3180	Ammonia monooxygenase
ISD32_RS07410	COG1486	melibiose metabolic process
ISD32_RS07415	COG0583	DNA-binding transcription factor activity
ISD32_RS07425	COG3106	COG3106 Predicted ATPase
ISD32_RS07435	COG1983	PspC domain protein
ISD32_RS07445	COG1842	Phage shock protein A
ISD32_RS07450	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
ISD32_RS07460	COG1473	amidohydrolase
ISD32_RS07475	COG0702	epimerase
ISD32_RS07490	COG4171	peptide transport system, permease
ISD32_RS07505	COG2986	histidine ammonia-lyase
ISD32_RS07535	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
ISD32_RS07540	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
ISD32_RS07540	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
ISD32_RS07555	COG1349	DNA-binding transcription factor activity
ISD32_RS07565	COG0023	Translation Initiation Factor
ISD32_RS07575	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
ISD32_RS07580	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
ISD32_RS07585	COG0671	phosphoesterase, PA-phosphatase related
ISD32_RS07595	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
ISD32_RS07620	COG0616	signal peptide processing
ISD32_RS07625	COG1028	Short-chain dehydrogenase reductase Sdr
ISD32_RS07630	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
ISD32_RS07655	COG0583	DNA-binding transcription factor activity
ISD32_RS07665	COG0009	L-threonylcarbamoyladenylate synthase
ISD32_RS07675	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
ISD32_RS07680	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
ISD32_RS07680	COG0512	Glutamine amidotransferase of anthranilate synthase
ISD32_RS07685	COG0134	indole-3-glycerol-phosphate synthase activity
ISD32_RS07685	COG0135	phosphoribosylanthranilate isomerase activity
ISD32_RS07730	COG4774	siderophore transport
ISD32_RS07740	COG3047	cAMP biosynthetic process
ISD32_RS07745	COG0727	PFAM Uncharacterised protein family (UPF0153)
ISD32_RS07775	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ISD32_RS07780	COG1028	Short-chain dehydrogenase reductase Sdr
ISD32_RS07785	COG1988	membrane-bound metal-dependent
ISD32_RS07790	COG1823	symporter activity
ISD32_RS07800	COG0753	catalase activity
ISD32_RS07810	COG1486	melibiose metabolic process
ISD32_RS07815	COG2169	Transcriptional regulator
ISD32_RS07815	COG1917	Cupin 2, conserved barrel domain protein
ISD32_RS07820	COG1447	Phosphotransferase system cellobiose-specific component IIA
ISD32_RS07825	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
ISD32_RS07835	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
ISD32_RS07840	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ISD32_RS07850	COG0322	excinuclease ABC activity
ISD32_RS07855	COG3678	ATP-independent chaperone mediated protein folding
ISD32_RS07865	COG3724	N-succinylarginine dihydrolase activity
ISD32_RS07875	COG3138	arginine N-succinyltransferase
ISD32_RS07885	COG0708	Exodeoxyribonuclease III
ISD32_RS07890	COG0398	Pfam SNARE associated Golgi protein
ISD32_RS07895	COG0398	Pfam SNARE associated Golgi protein
ISD32_RS07900	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
ISD32_RS07905	COG4134	Bacterial extracellular solute-binding protein
ISD32_RS07910	COG4135	transport system, permease component
ISD32_RS07915	COG4136	ATPase activity
ISD32_RS07920	COG2897	thiosulfate sulfurtransferase activity
ISD32_RS07925	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
ISD32_RS07930	COG0494	nUDIX hydrolase
ISD32_RS07935	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
ISD32_RS07940	COG3321	synthase
ISD32_RS07940	COG0604	alcohol dehydrogenase
ISD32_RS07940	COG1028	Short-chain dehydrogenase reductase Sdr
ISD32_RS07945	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
ISD32_RS07950	COG0709	Synthesizes selenophosphate from selenide and ATP
ISD32_RS07960	COG0778	Nitroreductase
ISD32_RS07965	COG0616	signal peptide processing
ISD32_RS07970	COG0252	asparaginase activity
ISD32_RS07975	COG1335	isochorismatase
ISD32_RS07980	COG2814	Major facilitator Superfamily
ISD32_RS07985	COG1349	DNA-binding transcription factor activity
ISD32_RS07990	COG0667	Aldo Keto reductase
ISD32_RS07995	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ISD32_RS08000	COG0191	fructose-bisphosphate aldolase activity
ISD32_RS08005	COG1063	alcohol dehydrogenase
ISD32_RS08010	COG2271	Major facilitator Superfamily
ISD32_RS08015	COG1063	alcohol dehydrogenase
ISD32_RS08030	COG3139	Protein of unknown function (DUF1315)
ISD32_RS08050	COG0656	L-ascorbic acid biosynthetic process
ISD32_RS08055	COG3713	MltA-interacting MipA family protein
ISD32_RS08060	COG2766	serine protein kinase
ISD32_RS08075	COG0386	Belongs to the glutathione peroxidase family
ISD32_RS08110	COG1126	abc transporter atp-binding protein
ISD32_RS08115	COG0765	amino acid transport
ISD32_RS08120	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ISD32_RS08130	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
ISD32_RS08145	COG0300	oxidoreductase activity
ISD32_RS08155	COG1902	pentaerythritol trinitrate reductase activity
ISD32_RS08165	COG1028	Short-chain dehydrogenase reductase Sdr
ISD32_RS08170	COG0583	DNA-binding transcription factor activity
ISD32_RS08190	COG1283	sodium-dependent phosphate transmembrane transporter activity
ISD32_RS08225	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ISD32_RS08230	COG0765	amino acid transport
ISD32_RS08235	COG1126	abc transporter atp-binding protein
ISD32_RS08240	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
ISD32_RS08250	COG0006	proline dipeptidase activity
ISD32_RS08255	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ISD32_RS08265	COG0436	Aminotransferase
ISD32_RS08275	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
ISD32_RS08295	COG0859	PFAM glycosyl transferase family 9
ISD32_RS08305	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
ISD32_RS08315	COG2207	Transcriptional regulator
ISD32_RS08320	COG2807	transmembrane transport
ISD32_RS08325	COG0504	CTP synthase activity
ISD32_RS08330	COG1683	Conserved Protein
ISD32_RS08335	COG3189	MarR family transcriptional regulator
ISD32_RS08340	COG3042	response to heat
ISD32_RS08345	COG2203	Gaf domain
ISD32_RS08345	COG2199	diguanylate cyclase activity
ISD32_RS08365	COG3182	Iron-regulated membrane protein
ISD32_RS08375	COG1560	Kdo2-lipid A biosynthetic process
ISD32_RS08385	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
ISD32_RS08390	COG3706	GGDEF domain
ISD32_RS08395	COG0583	DNA-binding transcription factor activity
ISD32_RS08400	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
ISD32_RS08430	COG2207	Transcriptional regulator
ISD32_RS08445	COG1566	PFAM secretion protein HlyD family protein
ISD32_RS08450	COG1294	oxidase, subunit
ISD32_RS08455	COG1271	oxidase subunit
ISD32_RS08460	COG3546	catalase activity
ISD32_RS08465	COG3685	Protein conserved in bacteria
ISD32_RS08470	COG3685	Protein conserved in bacteria
ISD32_RS08475	COG3729	General stress protein
ISD32_RS08480	COG1063	alcohol dehydrogenase
ISD32_RS08485	COG3813	Protein conserved in bacteria
ISD32_RS08510	COG0640	Transcriptional regulator
ISD32_RS08515	COG0538	isocitrate dehydrogenase activity
ISD32_RS08525	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
ISD32_RS08535	COG1472	Belongs to the glycosyl hydrolase 3 family
ISD32_RS08555	COG0538	isocitrate dehydrogenase activity
ISD32_RS08560	COG4943	cyclic-guanylate-specific phosphodiesterase activity
ISD32_RS08565	COG3706	GGDEF domain
ISD32_RS08650	COG0616	signal peptide processing
ISD32_RS08665	COG1802	Transcriptional regulator
ISD32_RS08665	COG4626	Terminase
ISD32_RS08710	COG3772	lysozyme
ISD32_RS08735	COG1403	HNH endonuclease
ISD32_RS08765	COG1349	DNA-binding transcription factor activity
ISD32_RS08815	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
ISD32_RS08825	COG0582	viral genome integration into host DNA
ISD32_RS08830	COG0538	isocitrate dehydrogenase activity
ISD32_RS08835	COG1187	pseudouridine synthase activity
ISD32_RS08855	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
ISD32_RS08875	COG2205	protein histidine kinase activity
ISD32_RS08880	COG2850	peptidyl-arginine hydroxylation
ISD32_RS08885	COG1943	Transposase
ISD32_RS08905	COG1177	transmembrane transport
ISD32_RS08920	COG0318	PFAM AMP-dependent synthetase and ligase
ISD32_RS08925	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
ISD32_RS08930	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
ISD32_RS08935	COG0698	ribose 5-phosphate isomerase
ISD32_RS08950	COG3395	kinase activity
ISD32_RS08965	COG2390	Transcriptional regulator
ISD32_RS08975	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
ISD32_RS08985	COG4591	ABC-type transport system involved in lipoprotein release permease component
ISD32_RS08995	COG4591	ABC-type transport system involved in lipoprotein release permease component
ISD32_RS09005	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
ISD32_RS09010	COG1376	ErfK ybiS ycfS ynhG family protein
ISD32_RS09010	COG1388	LysM domain
ISD32_RS09025	COG1309	transcriptional regulator
ISD32_RS09040	COG3134	Outer membrane lipoprotein
ISD32_RS09045	COG1252	NADH dehydrogenase
ISD32_RS09070	COG5633	Lipoprotein
ISD32_RS09075	COG0537	adenosine 5'-monophosphoramidase activity
ISD32_RS09085	COG0084	hydrolase, TatD family'
ISD32_RS09090	COG0470	DNA polymerase III
ISD32_RS09100	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
ISD32_RS09105	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
ISD32_RS09110	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
ISD32_RS09125	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
ISD32_RS09145	COG1399	metal-binding, possibly nucleic acid-binding protein
ISD32_RS09150	COG0424	maF-like protein
ISD32_RS09165	COG1530	ribonuclease E activity
ISD32_RS09170	COG0583	DNA-binding transcription factor activity
ISD32_RS09175	COG2814	Major facilitator Superfamily
ISD32_RS09195	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
ISD32_RS09240	COG1560	Kdo2-lipid A biosynthetic process
ISD32_RS09255	COG5645	(Lipo)protein
ISD32_RS09290	COG3381	protein complex oligomerization
ISD32_RS09325	COG1309	transcriptional regulator
ISD32_RS09330	COG0583	DNA-binding transcription factor activity
ISD32_RS09340	COG1335	isochorismatase
ISD32_RS09350	COG1702	phosphate starvation-inducible protein PhoH
ISD32_RS09370	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
ISD32_RS09380	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ISD32_RS09395	COG1309	transcriptional regulator
ISD32_RS09430	COG2233	PERMEase
ISD32_RS09445	COG3729	General stress protein
ISD32_RS09480	COG1028	Short-chain dehydrogenase reductase Sdr
ISD32_RS09495	COG0531	amino acid
ISD32_RS09500	COG0174	glutamine synthetase
ISD32_RS09505	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
ISD32_RS09510	COG1917	Cupin 2, conserved barrel domain protein
ISD32_RS09510	COG1396	sequence-specific DNA binding
ISD32_RS09515	COG1012	belongs to the aldehyde dehydrogenase family
ISD32_RS09520	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ISD32_RS09525	COG0583	DNA-binding transcription factor activity
ISD32_RS09530	COG0473	3-isopropylmalate dehydrogenase activity
ISD32_RS09535	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
ISD32_RS09540	COG4638	Rieske (2fe-2S)
ISD32_RS09545	COG1012	belongs to the aldehyde dehydrogenase family
ISD32_RS09550	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
ISD32_RS09555	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
ISD32_RS09555	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
ISD32_RS09555	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
ISD32_RS09560	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ISD32_RS09565	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ISD32_RS09570	COG1882	Formate acetyltransferase
ISD32_RS09575	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
ISD32_RS09580	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ISD32_RS09590	COG2207	Transcriptional regulator
ISD32_RS09595	COG3706	GGDEF domain
ISD32_RS09615	COG2200	EAL domain
ISD32_RS09625	COG0058	SHG alpha-glucan phosphorylase activity
ISD32_RS09640	COG0670	Belongs to the BI1 family
ISD32_RS09655	COG2207	Transcriptional regulator
ISD32_RS09660	COG1881	PFAM PEBP family protein
ISD32_RS09675	COG1832	CoA-binding protein
ISD32_RS09685	COG0210	DNA helicase
ISD32_RS09690	COG3304	Inner membrane component domain
ISD32_RS09695	COG1289	transmembrane transporter activity
ISD32_RS09700	COG3070	regulator of competence-specific genes
ISD32_RS09720	COG1067	ATP-dependent peptidase activity
ISD32_RS09730	COG3130	regulation of translation
ISD32_RS09735	COG3009	Protein conserved in bacteria
ISD32_RS09740	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
ISD32_RS09740	COG3008	intermembrane lipid transfer
ISD32_RS09745	COG2995	paraquat-inducible protein a
ISD32_RS09750	COG0488	(ABC) transporter
ISD32_RS09760	COG0633	Ferredoxin
ISD32_RS09760	COG3217	Mosc domain protein beta barrel domain protein
ISD32_RS09775	COG0431	NADPH-dependent FMN reductase
ISD32_RS09780	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
ISD32_RS09785	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ISD32_RS09790	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ISD32_RS09800	COG0308	aminopeptidase N
ISD32_RS09805	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
ISD32_RS09815	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
ISD32_RS09820	COG1448	Aminotransferase
ISD32_RS09825	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ISD32_RS09830	COG3108	Peptidase M15
ISD32_RS09835	COG2989	Protein conserved in bacteria
ISD32_RS09845	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
ISD32_RS09855	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
ISD32_RS09860	COG1434	Gram-negative-bacterium-type cell wall biogenesis
ISD32_RS09865	COG3173	Aminoglycoside phosphotransferase
ISD32_RS09880	COG3214	Protein conserved in bacteria
ISD32_RS09895	COG0658	competence protein
ISD32_RS09895	COG2333	competence protein COMEC
ISD32_RS09905	COG0539	negative regulation of cytoplasmic translation
ISD32_RS09925	COG2323	membrane
ISD32_RS09930	COG1944	ATP diphosphatase activity
ISD32_RS09935	COG2116	formate transmembrane transporter activity
ISD32_RS09940	COG1882	Formate acetyltransferase
ISD32_RS09945	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
ISD32_RS09950	COG0477	Major facilitator Superfamily
ISD32_RS09955	COG3302	dmso reductase anchor subunit
ISD32_RS09960	COG0437	4 iron, 4 sulfur cluster binding
ISD32_RS09965	COG0243	molybdopterin cofactor binding
ISD32_RS09975	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
ISD32_RS09995	COG0492	ferredoxin-NADP+ reductase activity
ISD32_RS10000	COG4988	ABC transporter
ISD32_RS10005	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
ISD32_RS10020	COG0542	response to heat
ISD32_RS10030	COG1278	Cold shock
ISD32_RS10040	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ISD32_RS10045	COG3593	DNA synthesis involved in DNA repair
ISD32_RS10055	COG2431	L-lysine efflux transmembrane transporter activity
ISD32_RS10065	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
ISD32_RS10075	COG0028	Belongs to the TPP enzyme family
ISD32_RS10080	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
ISD32_RS10085	COG0702	epimerase
ISD32_RS10090	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ISD32_RS10095	COG3023	N-Acetylmuramoyl-L-alanine amidase
ISD32_RS10100	COG3706	GGDEF domain
ISD32_RS10100	COG4251	negative regulation of phosphorylation
ISD32_RS10100	COG5001	Diguanylate cyclase
ISD32_RS10100	COG2203	Gaf domain
ISD32_RS10115	COG1126	abc transporter atp-binding protein
ISD32_RS10120	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ISD32_RS10125	COG4215	(ABC) transporter
ISD32_RS10130	COG4160	amino acid transport
ISD32_RS10135	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ISD32_RS10140	COG5002	protein histidine kinase activity
ISD32_RS10145	COG0745	RESPONSE REGULATOR receiver
ISD32_RS10160	COG1177	transmembrane transport
ISD32_RS10165	COG1176	ABC-type spermidine putrescine transport system, permease component I
ISD32_RS10170	COG3842	ATPase activity
ISD32_RS10175	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
ISD32_RS10190	COG0778	Nitroreductase
ISD32_RS10215	COG3226	Transcriptional regulator
ISD32_RS10220	COG0738	Major facilitator superfamily
ISD32_RS10225	COG0561	phosphatase activity
ISD32_RS10230	COG2814	Major facilitator Superfamily
ISD32_RS10235	COG0671	phosphoesterase, PA-phosphatase related
ISD32_RS10240	COG1349	DNA-binding transcription factor activity
ISD32_RS10245	COG1686	Belongs to the peptidase S11 family
ISD32_RS10250	COG0625	glutathione transferase activity
ISD32_RS10255	COG2133	pyrroloquinoline quinone binding
ISD32_RS10265	COG2223	nitrite transmembrane transporter activity
ISD32_RS10290	COG0747	negative chemotaxis
ISD32_RS10300	COG1446	asparaginase
ISD32_RS10305	COG0303	'Molybdopterin
ISD32_RS10310	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
ISD32_RS10315	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
ISD32_RS10320	COG1882	Formate acetyltransferase
ISD32_RS10325	COG0561	phosphatase activity
ISD32_RS10335	COG1609	Transcriptional regulator
ISD32_RS10340	COG2271	Major facilitator Superfamily
ISD32_RS10350	COG0488	(ABC) transporter
ISD32_RS10360	COG1376	ErfK ybiS ycfS ynhG family protein
ISD32_RS10365	COG2188	Transcriptional regulator
ISD32_RS10370	COG2723	6-phospho-beta-galactosidase activity
ISD32_RS10375	COG0667	Aldo Keto reductase
ISD32_RS10380	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
ISD32_RS10395	COG2194	sulfuric ester hydrolase activity
ISD32_RS10400	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
ISD32_RS10415	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ISD32_RS10420	COG0765	amino acid transport
ISD32_RS10425	COG1126	abc transporter atp-binding protein
ISD32_RS10430	COG0668	transmembrane transport
ISD32_RS10440	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
ISD32_RS10450	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
ISD32_RS10460	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
ISD32_RS10465	COG1199	ATP-dependent helicase activity
ISD32_RS10470	COG0513	Belongs to the DEAD box helicase family
ISD32_RS10475	COG3958	Transketolase
ISD32_RS10480	COG3959	Transketolase, thiamine diphosphate binding domain
ISD32_RS10485	COG1028	Short-chain dehydrogenase reductase Sdr
ISD32_RS10490	COG2271	Major facilitator Superfamily
ISD32_RS10495	COG0583	DNA-binding transcription factor activity
ISD32_RS10500	COG1309	transcriptional regulator
ISD32_RS10505	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ISD32_RS10510	COG1131	(ABC) transporter
ISD32_RS10515	COG0842	Transport permease protein
ISD32_RS10520	COG0842	Transport permease protein
ISD32_RS10530	COG3568	Endonuclease Exonuclease Phosphatase
ISD32_RS10535	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ISD32_RS10540	COG0392	lysyltransferase activity
ISD32_RS10545	COG0670	Belongs to the BI1 family
ISD32_RS10550	COG0314	molybdopterin synthase activity
ISD32_RS10555	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
ISD32_RS10565	COG0521	Mo-molybdopterin cofactor biosynthetic process
ISD32_RS10590	COG0642	Histidine kinase
ISD32_RS10615	COG2226	methyltransferase
ISD32_RS10630	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
ISD32_RS10635	COG1881	PFAM PEBP family protein
ISD32_RS10675	COG4677	pectinesterase activity
ISD32_RS10685	COG0589	response to stress
ISD32_RS10690	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ISD32_RS10720	COG0789	Transcriptional regulator
ISD32_RS10725	COG2200	EAL domain
ISD32_RS10750	COG0561	phosphatase activity
ISD32_RS10760	COG4149	molybdate abc transporter
ISD32_RS10765	COG0725	ABC transporter, periplasmic molybdate-binding protein
ISD32_RS10775	COG2005	Transcriptional regulator
ISD32_RS10775	COG3585	molybdate ion transport
ISD32_RS10780	COG1119	ATPase activity
ISD32_RS10790	COG1085	galactose-1-phosphate uridylyltransferase
ISD32_RS10800	COG2017	converts alpha-aldose to the beta-anomer
ISD32_RS10835	COG0471	metal ion transport
ISD32_RS10835	COG0490	domain, Protein
ISD32_RS10855	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
ISD32_RS10855	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
ISD32_RS10860	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
ISD32_RS10870	COG1230	cation diffusion facilitator family transporter
ISD32_RS10875	COG3201	nicotinamide mononucleotide transporter
ISD32_RS10880	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
ISD32_RS10925	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
ISD32_RS10930	COG2885	chlorophyll binding
ISD32_RS10940	COG3064	Membrane
ISD32_RS10940	COG3064	Membrane
ISD32_RS10945	COG0848	biopolymer transport protein
ISD32_RS10950	COG0811	peptide transport
ISD32_RS10955	COG0824	Thioesterase
ISD32_RS10960	COG3790	cyd operon protein YbgE
ISD32_RS10965	COG4890	Cyd operon protein YbgT
ISD32_RS10970	COG1294	oxidase, subunit
ISD32_RS10975	COG1271	oxidase subunit
ISD32_RS10980	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
ISD32_RS10990	COG0508	dehydrogenase complex catalyzes the overall conversion of
ISD32_RS10995	COG0567	Dehydrogenase, E1 component
ISD32_RS11000	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
ISD32_RS11005	COG1053	succinate dehydrogenase
ISD32_RS11010	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
ISD32_RS11015	COG2009	succinate dehydrogenase
ISD32_RS11040	COG1984	allophanate hydrolase subunit 2
ISD32_RS11045	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
ISD32_RS11090	COG2205	protein histidine kinase activity
ISD32_RS11095	COG0745	RESPONSE REGULATOR receiver
ISD32_RS11105	COG0033	Phosphoglucomutase
ISD32_RS11115	COG0596	Alpha beta hydrolase
ISD32_RS11130	COG0735	belongs to the Fur family
ISD32_RS11135	COG0583	DNA-binding transcription factor activity
ISD32_RS11140	COG1053	succinate dehydrogenase
ISD32_RS11185	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
ISD32_RS11190	COG1846	Transcriptional regulator
ISD32_RS11190	COG1940	carbohydrate kinase activity
ISD32_RS11195	COG0647	UMP catabolic process
ISD32_RS11200	COG0367	asparagine synthase
ISD32_RS11240	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ISD32_RS11250	COG1702	phosphate starvation-inducible protein PhoH
ISD32_RS11275	COG0765	amino acid transport
ISD32_RS11280	COG0765	amino acid transport
ISD32_RS11285	COG1126	abc transporter atp-binding protein
ISD32_RS11300	COG2888	peptidyl-tyrosine sulfation
ISD32_RS11315	COG1466	dna polymerase III delta subunit
ISD32_RS11330	COG0799	negative regulation of ribosome biogenesis
ISD32_RS11340	COG0768	penicillin binding
ISD32_RS11345	COG0772	Belongs to the SEDS family
ISD32_RS11350	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
ISD32_RS11355	COG1686	Belongs to the peptidase S11 family
ISD32_RS11370	COG0583	DNA-binding transcription factor activity
ISD32_RS11380	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
ISD32_RS11385	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
ISD32_RS11405	COG3069	C4-dicarboxylate transmembrane transporter activity
ISD32_RS11410	COG3719	Belongs to the RNase T2 family
ISD32_RS11415	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
ISD32_RS11435	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
ISD32_RS11440	COG0583	DNA-binding transcription factor activity
ISD32_RS11445	COG3969	phosphoadenosine phosphosulfate
ISD32_RS11450	COG1475	DNA binding
ISD32_RS11455	COG0436	Aminotransferase
ISD32_RS11480	COG1129	ABC transporter
ISD32_RS11485	COG1172	Belongs to the binding-protein-dependent transport system permease family
ISD32_RS11490	COG1172	Belongs to the binding-protein-dependent transport system permease family
ISD32_RS11500	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
ISD32_RS11515	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
ISD32_RS11525	COG0402	S-adenosylhomocysteine deaminase activity
ISD32_RS11535	COG0483	inositol monophosphate 1-phosphatase activity
ISD32_RS11540	COG2271	Major facilitator Superfamily
ISD32_RS11570	COG1172	Belongs to the binding-protein-dependent transport system permease family
ISD32_RS11575	COG1129	ABC transporter
ISD32_RS11580	COG0371	Dehydrogenase
ISD32_RS11585	COG1028	Short-chain dehydrogenase reductase Sdr
ISD32_RS11600	COG2879	small protein
ISD32_RS11605	COG1966	Carbon starvation protein
ISD32_RS11615	COG1028	Short-chain dehydrogenase reductase Sdr
ISD32_RS11620	COG3433	isochorismatase activity
ISD32_RS11620	COG1535	isochorismatase
ISD32_RS11625	COG1021	2,3-dihydroxybenzoate-AMP ligase
ISD32_RS11630	COG1169	isochorismate synthase
ISD32_RS11635	COG4592	Periplasmic binding protein
ISD32_RS11645	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ISD32_RS11650	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ISD32_RS11655	COG1120	ATPase activity
ISD32_RS11670	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
ISD32_RS11670	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
ISD32_RS11675	COG3251	PFAM MbtH domain protein
ISD32_RS11680	COG2382	esterase
ISD32_RS11685	COG4771	TonB-dependent receptor
ISD32_RS11690	COG2977	Belongs to the P-Pant transferase superfamily
ISD32_RS11695	COG3958	Transketolase
ISD32_RS11700	COG3959	Transketolase, thiamine diphosphate binding domain
ISD32_RS11705	COG2390	Transcriptional regulator
ISD32_RS11710	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
ISD32_RS11715	COG1879	ABC-type sugar transport system periplasmic component
ISD32_RS11725	COG1129	ABC transporter
ISD32_RS11730	COG1172	Belongs to the binding-protein-dependent transport system permease family
ISD32_RS11740	COG1028	Short-chain dehydrogenase reductase Sdr
ISD32_RS11750	COG0583	DNA-binding transcription factor activity
ISD32_RS11755	COG0668	transmembrane transport
ISD32_RS11765	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
ISD32_RS11790	COG0747	negative chemotaxis
ISD32_RS11795	COG0601	transmembrane transport
ISD32_RS11800	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ISD32_RS11805	COG0444	Belongs to the ABC transporter superfamily
ISD32_RS11810	COG4608	Belongs to the ABC transporter superfamily
ISD32_RS11815	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
ISD32_RS11820	COG4221	oxidoreductase activity
ISD32_RS11830	COG4215	(ABC) transporter
ISD32_RS11835	COG0765	amino acid transport
ISD32_RS11840	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
ISD32_RS11855	COG0697	spore germination
ISD32_RS11870	COG4608	Belongs to the ABC transporter superfamily
ISD32_RS11875	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ISD32_RS11885	COG4166	transmembrane transport
ISD32_RS11895	COG3698	Phosphodiester glycosidase
ISD32_RS11935	COG2315	Protein conserved in bacteria
ISD32_RS11940	COG0778	Nitroreductase
ISD32_RS11950	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ISD32_RS11960	COG3716	PTS system mannose fructose sorbose family IID component
ISD32_RS11965	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
ISD32_RS11970	COG2222	sugar isomerase
ISD32_RS11975	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
ISD32_RS11975	COG3933	PFAM sigma-54 factor interaction domain-containing protein
ISD32_RS11990	COG0477	Major facilitator Superfamily
ISD32_RS11995	COG0668	transmembrane transport
ISD32_RS12000	COG1609	Transcriptional regulator
ISD32_RS12010	COG0673	inositol 2-dehydrogenase activity
ISD32_RS12020	COG2211	Major facilitator Superfamily
ISD32_RS12025	COG1113	amino acid transport
ISD32_RS12040	COG1012	belongs to the aldehyde dehydrogenase family
ISD32_RS12045	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ISD32_RS12055	COG0531	amino acid
ISD32_RS12090	COG0667	Aldo Keto reductase
ISD32_RS12095	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ISD32_RS12100	COG1473	amidohydrolase
ISD32_RS12125	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ISD32_RS12130	COG1120	ATPase activity
ISD32_RS12135	COG1566	PFAM secretion protein HlyD family protein
ISD32_RS12180	COG4211	Belongs to the binding-protein-dependent transport system permease family
ISD32_RS12185	COG1129	ABC transporter
ISD32_RS12200	COG0673	inositol 2-dehydrogenase activity
ISD32_RS12240	COG3104	oligopeptide transport
ISD32_RS12245	COG1982	Orn Lys Arg decarboxylase major
ISD32_RS12250	COG0531	amino acid
ISD32_RS12255	COG3710	Transcriptional regulator
ISD32_RS12265	COG1560	Kdo2-lipid A biosynthetic process
ISD32_RS12275	COG3539	Fimbrial protein
ISD32_RS12280	COG3188	usher protein
ISD32_RS12285	COG3121	Chaperone
ISD32_RS12290	COG3539	Fimbrial protein
ISD32_RS12345	COG2501	S4 domain
ISD32_RS12355	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
ISD32_RS12370	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
ISD32_RS12375	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
ISD32_RS12395	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
ISD32_RS12400	COG4181	ATPase activity
ISD32_RS12405	COG2755	lipolytic protein G-D-S-L family
ISD32_RS12410	COG0300	oxidoreductase activity
ISD32_RS12415	COG3118	belongs to the thioredoxin family
ISD32_RS12420	COG0390	transport system, permease component
ISD32_RS12425	COG4619	ABC transporter
ISD32_RS12430	COG0330	HflC and HflK could
ISD32_RS12435	COG1585	Membrane protein implicated in regulation of membrane protease activity
ISD32_RS12450	COG3735	TraB family
ISD32_RS12455	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
ISD32_RS12465	COG2223	nitrite transmembrane transporter activity
ISD32_RS12470	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
ISD32_RS12470	COG4651	solute:proton antiporter activity
ISD32_RS12475	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ISD32_RS12515	COG2832	Protein of unknown function (DUF454)
ISD32_RS12520	COG3923	Primosomal replication protein n
ISD32_RS12535	COG3264	Mechanosensitive ion channel
ISD32_RS12535	COG1196	nuclear chromosome segregation
ISD32_RS12540	COG1309	transcriptional regulator
ISD32_RS12545	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ISD32_RS12550	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ISD32_RS12565	COG0110	maltose O-acetyltransferase activity
ISD32_RS12615	COG1874	Beta-galactosidase
ISD32_RS12620	COG3867	Arabinogalactan endo-beta-1,4-galactanase
ISD32_RS12625	COG3833	ABC-type maltose transport systems, permease component
ISD32_RS12630	COG1175	transmembrane transport
ISD32_RS12635	COG2182	Extracellular solute-binding protein
ISD32_RS12645	COG4943	cyclic-guanylate-specific phosphodiesterase activity
ISD32_RS12660	COG2364	Membrane
ISD32_RS12690	COG3695	enzyme binding
ISD32_RS12695	COG3126	Type III secretion system lipoprotein chaperone (YscW)
ISD32_RS12700	COG1946	Acyl-CoA thioesterase
ISD32_RS12705	COG0004	ammonium transporteR
ISD32_RS12710	COG0347	Belongs to the P(II) protein family
ISD32_RS12715	COG1132	(ABC) transporter
ISD32_RS12720	COG1132	(ABC) transporter
ISD32_RS12725	COG1522	sequence-specific DNA binding
ISD32_RS12740	COG4533	DNA binding
ISD32_RS12750	COG0824	Thioesterase
ISD32_RS12755	COG1555	photosystem II stabilization
ISD32_RS12760	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
ISD32_RS12765	COG0776	regulation of translation
ISD32_RS12770	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
ISD32_RS12790	COG0271	Belongs to the BolA IbaG family
ISD32_RS12795	COG3056	Lipoprotein
ISD32_RS12800	COG2223	nitrite transmembrane transporter activity
ISD32_RS12805	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
ISD32_RS12810	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
ISD32_RS12815	COG1845	cytochrome c oxidase, subunit III
ISD32_RS12820	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
ISD32_RS12835	COG1414	Transcriptional regulator
ISD32_RS12840	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
ISD32_RS12845	COG1053	succinate dehydrogenase
ISD32_RS12855	COG1053	succinate dehydrogenase
ISD32_RS12870	COG0673	inositol 2-dehydrogenase activity
ISD32_RS12875	COG2814	Major facilitator Superfamily
ISD32_RS12885	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
ISD32_RS12910	COG0142	geranyltranstransferase activity
ISD32_RS12920	COG0667	Aldo Keto reductase
ISD32_RS12925	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
ISD32_RS12930	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
ISD32_RS12945	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ISD32_RS12945	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ISD32_RS12955	COG4238	major outer membrane lipoprotein
ISD32_RS12975	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ISD32_RS12980	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ISD32_RS12985	COG1862	Preprotein translocase
ISD32_RS13010	COG0450	alkyl hydroperoxide reductase
ISD32_RS13020	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
ISD32_RS13035	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ISD32_RS13045	COG1228	amidohydrolase
ISD32_RS13055	COG1335	isochorismatase
ISD32_RS13060	COG0583	DNA-binding transcription factor activity
ISD32_RS13065	COG0366	Alpha amylase catalytic
ISD32_RS13095	COG0420	3'-5' exonuclease activity
ISD32_RS13100	COG0419	ATPase involved in DNA repair
ISD32_RS13105	COG1940	carbohydrate kinase activity
ISD32_RS13120	COG4126	flavin adenine dinucleotide binding
ISD32_RS13130	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
ISD32_RS13135	COG3416	Protein conserved in bacteria
ISD32_RS13145	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
ISD32_RS13155	COG1785	Belongs to the alkaline phosphatase family
ISD32_RS13195	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
ISD32_RS13200	COG1335	isochorismatase
ISD32_RS13205	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
ISD32_RS13210	COG0113	porphobilinogen synthase activity
ISD32_RS13215	COG1943	Transposase
ISD32_RS13225	COG2175	clavaminate synthase activity
ISD32_RS13230	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ISD32_RS13235	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
ISD32_RS13240	COG4521	taurine ABC transporter
ISD32_RS13245	COG2040	homocysteine
ISD32_RS13250	COG0833	amino acid
ISD32_RS13265	COG4303	Ethanolamine ammonia lyase large subunit
ISD32_RS13270	COG4302	ethanolamine ammonia-lyase activity
ISD32_RS13310	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ISD32_RS13315	COG1126	abc transporter atp-binding protein
ISD32_RS13320	COG4597	amino acid ABC transporter
ISD32_RS13325	COG0765	amino acid transport
ISD32_RS13340	COG3188	usher protein
ISD32_RS13365	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
ISD32_RS13375	COG3639	organic phosphonate transmembrane transporter activity
ISD32_RS13390	COG0791	NLP P60 protein
ISD32_RS13415	COG0582	viral genome integration into host DNA
ISD32_RS13465	COG2003	Belongs to the UPF0758 family
ISD32_RS13485	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ISD32_RS13490	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
ISD32_RS13495	COG1116	anion transmembrane transporter activity
ISD32_RS13515	COG2207	Transcriptional regulator
ISD32_RS13525	COG0518	GMP synthase (glutamine-hydrolyzing) activity
ISD32_RS13525	COG0519	Catalyzes the synthesis of GMP from XMP
ISD32_RS13535	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
ISD32_RS13540	COG0022	dehydrogenase e1 component
ISD32_RS13545	COG0508	dehydrogenase complex catalyzes the overall conversion of
ISD32_RS13550	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ISD32_RS13570	COG1070	Carbohydrate kinase
ISD32_RS13575	COG1028	Short-chain dehydrogenase reductase Sdr
ISD32_RS13580	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
ISD32_RS13585	COG3775	system Galactitol-specific IIC component
ISD32_RS13590	COG0625	glutathione transferase activity
ISD32_RS13595	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
ISD32_RS13610	COG0579	oxidoreductase
ISD32_RS13615	COG1012	belongs to the aldehyde dehydrogenase family
ISD32_RS13620	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
ISD32_RS13625	COG1113	amino acid transport
ISD32_RS13630	COG1802	Transcriptional regulator
ISD32_RS13635	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
ISD32_RS13645	COG1596	polysaccharide export
ISD32_RS13665	COG0463	Glycosyl transferase, family 2
ISD32_RS13670	COG0438	transferase activity, transferring glycosyl groups
ISD32_RS13675	COG0438	transferase activity, transferring glycosyl groups
ISD32_RS13675	COG0297	glycogen (starch) synthase activity
ISD32_RS13690	COG1045	serine acetyltransferase
ISD32_RS13710	COG2195	Cleaves the N-terminal amino acid of tripeptides
ISD32_RS13715	COG0454	-acetyltransferase
ISD32_RS13730	COG2991	Protein conserved in bacteria
ISD32_RS13745	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
ISD32_RS13750	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
ISD32_RS13765	COG3034	peptidoglycan biosynthetic process
ISD32_RS13770	COG0121	glutamine amidotransferase
ISD32_RS13780	COG1960	acyl-CoA dehydrogenase activity
ISD32_RS13785	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
ISD32_RS13800	COG0583	DNA-binding transcription factor activity
ISD32_RS13820	COG2226	methyltransferase
ISD32_RS13830	COG1388	LysM domain
ISD32_RS13830	COG0741	lytic transglycosylase activity
ISD32_RS13835	COG2226	methyltransferase
ISD32_RS13845	COG2814	Major facilitator Superfamily
ISD32_RS13850	COG0583	DNA-binding transcription factor activity
ISD32_RS13855	COG0656	L-ascorbic acid biosynthetic process
ISD32_RS13890	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
ISD32_RS13900	COG2011	ABC-type metal ion transport system permease component
ISD32_RS13905	COG1464	Belongs to the NlpA lipoprotein family
ISD32_RS13915	COG1720	tRNA m6t6A37 methyltransferase activity
ISD32_RS13925	COG0791	NLP P60 protein
ISD32_RS13930	COG3015	lipoprotein NlpE involved in copper resistance
ISD32_RS13935	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
ISD32_RS13950	COG4568	rho-dependent transcription termination
ISD32_RS13960	COG0346	lactoylglutathione lyase activity
ISD32_RS13965	COG1982	Orn Lys Arg decarboxylase major
ISD32_RS14005	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
ISD32_RS14015	COG0750	zinc metalloprotease
ISD32_RS14020	COG0575	Belongs to the CDS family
ISD32_RS14055	COG0024	Methionine aminopeptidase
ISD32_RS14060	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
ISD32_RS14075	COG3835	regulator
ISD32_RS14080	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ISD32_RS14100	COG2860	membrane
ISD32_RS14120	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ISD32_RS14125	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
ISD32_RS14130	COG1120	ATPase activity
ISD32_RS14135	COG4774	siderophore transport
ISD32_RS14140	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
ISD32_RS14235	COG1643	Atp-dependent helicase
ISD32_RS14240	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
ISD32_RS14260	COG0617	tRNA 3'-terminal CCA addition
ISD32_RS14265	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
ISD32_RS14285	COG0726	polysaccharide deacetylase
ISD32_RS14290	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
ISD32_RS14295	COG0842	Transport permease protein
ISD32_RS14300	COG1131	(ABC) transporter
ISD32_RS14305	COG0288	reversible hydration of carbon dioxide
ISD32_RS14320	COG4993	Dehydrogenase
ISD32_RS14325	COG2132	Multicopper oxidase
ISD32_RS14340	COG0545	Peptidyl-prolyl cis-trans isomerase
ISD32_RS14365	COG3064	Membrane
ISD32_RS14380	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ISD32_RS14385	COG0508	dehydrogenase complex catalyzes the overall conversion of
ISD32_RS14390	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
ISD32_RS14395	COG2186	Transcriptional regulator
ISD32_RS14400	COG1113	amino acid transport
ISD32_RS14405	COG2211	Major facilitator Superfamily
ISD32_RS14410	COG3940	Belongs to the glycosyl hydrolase 43 family
ISD32_RS14415	COG3725	Membrane protein required for beta-lactamase induction
ISD32_RS14420	COG3023	N-Acetylmuramoyl-L-alanine amidase
ISD32_RS14430	COG4969	Belongs to the N-Me-Phe pilin family
ISD32_RS14435	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
ISD32_RS14440	COG1459	type II secretion system
ISD32_RS14465	COG0494	nUDIX hydrolase
ISD32_RS14485	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
ISD32_RS14490	COG0849	cell division
ISD32_RS14500	COG1181	Belongs to the D-alanine--D-alanine ligase family
ISD32_RS14515	COG0772	Belongs to the SEDS family
ISD32_RS14530	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
ISD32_RS14540	COG0768	penicillin binding
ISD32_RS14560	COG1609	Transcriptional regulator
ISD32_RS14570	COG0028	Belongs to the TPP enzyme family
ISD32_RS14610	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
ISD32_RS14615	COG0738	Major facilitator superfamily
ISD32_RS14625	COG0583	DNA-binding transcription factor activity
ISD32_RS14630	COG2271	Major facilitator Superfamily
ISD32_RS14635	COG2814	Major facilitator Superfamily
ISD32_RS14655	COG1178	ABC-type Fe3 transport system permease component
ISD32_RS14665	COG0586	Pfam SNARE associated Golgi protein
ISD32_RS14685	COG0235	Class ii aldolase
ISD32_RS14690	COG0417	DNA replication proofreading
ISD32_RS14700	COG0564	pseudouridine synthase activity
ISD32_RS14710	COG3493	citrate carrier protein
ISD32_RS14725	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
ISD32_RS14730	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
ISD32_RS14740	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
ISD32_RS14775	COG2271	Major facilitator Superfamily
ISD32_RS14780	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
ISD32_RS14785	COG1609	Transcriptional regulator
ISD32_RS14790	COG1028	Short-chain dehydrogenase reductase Sdr
ISD32_RS14795	COG3265	gluconokinase activity
ISD32_RS14800	COG2731	YhcH YjgK YiaL family protein
ISD32_RS14815	COG0505	Belongs to the CarA family
ISD32_RS14895	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
ISD32_RS14900	COG0471	metal ion transport
ISD32_RS14905	COG0471	metal ion transport
ISD32_RS14910	COG2828	Protein conserved in bacteria
ISD32_RS14915	COG0583	DNA-binding transcription factor activity
ISD32_RS14930	COG1047	Peptidyl-prolyl cis-trans
ISD32_RS14945	COG0196	riboflavin kinase activity
ISD32_RS14955	COG0583	DNA-binding transcription factor activity
ISD32_RS14980	COG4735	regulation of single-species biofilm formation
ISD32_RS14985	COG1584	GPR1 FUN34 yaaH family protein
ISD32_RS14990	COG0477	Major facilitator Superfamily
ISD32_RS14995	COG0521	Mo-molybdopterin cofactor biosynthetic process
ISD32_RS15000	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
ISD32_RS15005	COG1115	amino acid carrier protein
ISD32_RS15020	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
ISD32_RS15030	COG0527	aspartate kinase activity
ISD32_RS15030	COG0460	homoserine dehydrogenase
ISD32_RS15040	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
ISD32_RS15050	COG0745	RESPONSE REGULATOR receiver
ISD32_RS15055	COG4452	Inner membrane protein CreD
ISD32_RS15060	COG2205	protein histidine kinase activity
ISD32_RS15065	COG0745	RESPONSE REGULATOR receiver
ISD32_RS15070	COG3045	CreA protein
ISD32_RS15075	COG3708	Transcriptional regulator
ISD32_RS15075	COG2207	Transcriptional regulator
ISD32_RS15095	COG0741	lytic transglycosylase activity
ISD32_RS15100	COG0488	(ABC) transporter
ISD32_RS15110	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
ISD32_RS15115	COG0560	Phosphoserine phosphatase
ISD32_RS15120	COG3726	membrane protein affecting hemolysin expression
ISD32_RS15150	COG0084	hydrolase, TatD family'
ISD32_RS15155	COG4667	esterase of the alpha-beta hydrolase superfamily
ISD32_RS15165	COG2823	Periplasmic or secreted lipoprotein
ISD32_RS15175	COG1011	Hydrolase
ISD32_RS15180	COG0456	acetyltransferase
ISD32_RS15185	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
ISD32_RS15220	COG3706	GGDEF domain
ISD32_RS15225	COG4114	ferric iron reductase
ISD32_RS15230	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
ISD32_RS15235	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
ISD32_RS15240	COG2197	response regulator
ISD32_RS15245	COG2197	response regulator
ISD32_RS15250	COG1917	Cupin 2, conserved barrel domain protein
ISD32_RS15250	COG2169	Transcriptional regulator
ISD32_RS15260	COG2966	Psort location CytoplasmicMembrane, score
ISD32_RS15275	COG1484	DNA-dependent DNA replication
ISD32_RS15290	COG5464	transposase or invertase
ISD32_RS15300	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
ISD32_RS15305	COG3716	PTS system mannose fructose sorbose family IID component
ISD32_RS15310	COG3715	PTS system
ISD32_RS15325	COG3933	PFAM sigma-54 factor interaction domain-containing protein
ISD32_RS15325	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
ISD32_RS15335	COG1063	alcohol dehydrogenase
ISD32_RS15340	COG1802	Transcriptional regulator
ISD32_RS15345	COG2271	Major facilitator Superfamily
ISD32_RS15350	COG1214	PFAM Peptidase M22, glycoprotease
ISD32_RS15350	COG0456	acetyltransferase
ISD32_RS15365	COG0531	amino acid
ISD32_RS15370	COG1012	belongs to the aldehyde dehydrogenase family
ISD32_RS15375	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ISD32_RS15405	COG1846	Transcriptional regulator
ISD32_RS15415	COG0179	Fumarylacetoacetate (FAA) hydrolase
ISD32_RS15425	COG1012	belongs to the aldehyde dehydrogenase family
ISD32_RS15430	COG3384	dioxygenase
ISD32_RS15440	COG3971	2-oxopent-4-enoate hydratase activity
ISD32_RS15460	COG2368	4-hydroxyphenylacetate
ISD32_RS15465	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
ISD32_RS15480	COG1966	Carbon starvation protein
ISD32_RS15485	COG2879	small protein
ISD32_RS15490	COG0523	cobalamin synthesis protein
ISD32_RS15505	COG1012	belongs to the aldehyde dehydrogenase family
ISD32_RS15510	COG5464	transposase or invertase
ISD32_RS15515	COG2207	Transcriptional regulator
ISD32_RS15515	COG1917	Cupin 2, conserved barrel domain protein
ISD32_RS15525	COG2733	membrane
ISD32_RS15540	COG1775	2-hydroxyglutaryl-CoA dehydratase, D-component
ISD32_RS15545	COG1924	4 iron, 4 sulfur cluster binding
ISD32_RS15555	COG1473	amidohydrolase
ISD32_RS15560	COG0700	Nucleoside recognition
ISD32_RS15565	COG3366	ferrous iron transmembrane transporter activity
ISD32_RS15570	COG0583	DNA-binding transcription factor activity
ISD32_RS15580	COG1566	PFAM secretion protein HlyD family protein
ISD32_RS15590	COG5457	Domain of unknown function (DUF1127)
ISD32_RS15595	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ISD32_RS15605	COG0583	DNA-binding transcription factor activity
ISD32_RS15610	COG2249	NAD(P)H dehydrogenase (quinone) activity
ISD32_RS15620	COG1172	Belongs to the binding-protein-dependent transport system permease family
ISD32_RS15625	COG1129	ABC transporter
ISD32_RS15630	COG1879	ABC-type sugar transport system periplasmic component
ISD32_RS15640	COG3706	GGDEF domain
ISD32_RS15645	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ISD32_RS15650	COG1129	ABC transporter
ISD32_RS15650	COG0842	Transport permease protein
ISD32_RS15655	COG0842	Transport permease protein
ISD32_RS15690	COG2850	peptidyl-arginine hydroxylation
ISD32_RS15695	COG5002	protein histidine kinase activity
ISD32_RS15700	COG0745	RESPONSE REGULATOR receiver
ISD32_RS15705	COG1538	Outer membrane efflux protein
ISD32_RS15710	COG5569	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ISD32_RS15715	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ISD32_RS15720	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ISD32_RS15730	COG3040	lipid binding
ISD32_RS15735	COG0789	Transcriptional regulator
ISD32_RS15740	COG3631	Ketosteroid isomerase-related protein
ISD32_RS15745	COG0300	oxidoreductase activity
ISD32_RS15760	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
ISD32_RS15780	COG3272	Protein of unknown function (DUF1722)
ISD32_RS15785	COG4580	involved in the transport of maltose and maltodextrins
ISD32_RS15795	COG2211	Major facilitator Superfamily
ISD32_RS15800	COG3507	Belongs to the glycosyl hydrolase 43 family
ISD32_RS15950	COG0582	viral genome integration into host DNA
ISD32_RS15960	COG0288	reversible hydration of carbon dioxide
ISD32_RS15965	COG0659	secondary active sulfate transmembrane transporter activity
ISD32_RS15970	COG1064	alcohol dehydrogenase
ISD32_RS15975	COG1175	transmembrane transport
ISD32_RS15980	COG0395	ABC-type sugar transport system, permease component
ISD32_RS15985	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
ISD32_RS15990	COG3842	ATPase activity
ISD32_RS15995	COG1653	transport
ISD32_RS16005	COG1082	Xylose isomerase domain protein TIM barrel
ISD32_RS16015	COG3962	Belongs to the TPP enzyme family
ISD32_RS16020	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ISD32_RS16025	COG1737	Transcriptional regulator
ISD32_RS16025	COG0837	glucose binding
ISD32_RS16030	COG3718	enzyme involved in inositol metabolism
ISD32_RS16045	COG0433	COG0433 Predicted ATPase
ISD32_RS16050	COG0795	lipopolysaccharide-transporting ATPase activity
ISD32_RS16055	COG0795	lipopolysaccharide-transporting ATPase activity
ISD32_RS16065	COG2927	DNA polymerase III (CHI subunit)
ISD32_RS16070	COG0525	valine-tRNA ligase activity
ISD32_RS16095	COG2731	YhcH YjgK YiaL family protein
ISD32_RS16130	COG1263	PTS System
ISD32_RS16130	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ISD32_RS16135	COG0366	Alpha amylase catalytic
ISD32_RS16145	COG0602	queuosine metabolic process
ISD32_RS16150	COG2026	Addiction module toxin, RelE StbE family
ISD32_RS16155	COG3077	Addiction module antitoxin, RelB DinJ family
ISD32_RS16160	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
ISD32_RS16160	COG3711	transcriptional antiterminator
ISD32_RS16165	COG2706	6-phosphogluconolactonase activity
ISD32_RS16180	COG3964	amidohydrolase
ISD32_RS16220	COG0312	modulator of DNA gyrase
ISD32_RS16240	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
ISD32_RS16250	COG1172	Belongs to the binding-protein-dependent transport system permease family
ISD32_RS16255	COG1172	Belongs to the binding-protein-dependent transport system permease family
ISD32_RS16260	COG1129	ABC transporter
ISD32_RS16265	COG1879	ABC-type sugar transport system periplasmic component
ISD32_RS16280	COG2105	PFAM AIG2 family protein
ISD32_RS16285	COG2911	Protein conserved in bacteria
ISD32_RS16290	COG0729	surface antigen
ISD32_RS16305	COG1914	H( )-stimulated, divalent metal cation uptake system
ISD32_RS16310	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ISD32_RS16315	COG1609	Transcriptional regulator
ISD32_RS16320	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
ISD32_RS16325	COG1253	flavin adenine dinucleotide binding
ISD32_RS16350	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
ISD32_RS16365	COG1733	regulation of RNA biosynthetic process
ISD32_RS16370	COG0702	epimerase
ISD32_RS16380	COG0697	spore germination
ISD32_RS16390	COG1113	amino acid transport
ISD32_RS16395	COG0545	Peptidyl-prolyl cis-trans isomerase
ISD32_RS16400	COG3061	Opacity-associated protein A
ISD32_RS16410	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
ISD32_RS16415	COG2965	DNA replication, synthesis of RNA primer
ISD32_RS16475	COG1073	alpha beta
ISD32_RS16480	COG3650	response to hydrogen peroxide
ISD32_RS16490	COG1960	acyl-CoA dehydrogenase activity
ISD32_RS16495	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ISD32_RS16500	COG0557	exoribonuclease II activity
ISD32_RS16515	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
ISD32_RS16525	COG0330	HflC and HflK could
ISD32_RS16530	COG0330	HflC and HflK could
ISD32_RS16535	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
ISD32_RS16560	COG0802	atpase or kinase
ISD32_RS16565	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
ISD32_RS16565	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
ISD32_RS16570	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
ISD32_RS16590	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ISD32_RS16610	COG3264	Mechanosensitive ion channel
ISD32_RS16610	COG1511	domain protein
ISD32_RS16625	COG1053	succinate dehydrogenase
ISD32_RS16630	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
ISD32_RS16650	COG2076	Multidrug Resistance protein
ISD32_RS16670	COG1509	lysine 2,3-aminomutase activity
ISD32_RS16735	COG0531	amino acid
ISD32_RS16740	COG3030	protein affecting phage T7 exclusion by the F plasmid
ISD32_RS16745	COG1027	Aspartate ammonia-lyase
ISD32_RS16750	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
ISD32_RS16765	COG1309	transcriptional regulator
ISD32_RS16815	COG1649	PFAM Uncharacterised BCR, COG1649
ISD32_RS16815	COG0726	polysaccharide deacetylase
ISD32_RS16820	COG1215	transferase activity, transferring glycosyl groups
ISD32_RS16835	COG0861	Integral membrane protein TerC family
ISD32_RS16870	COG1486	melibiose metabolic process
ISD32_RS16875	COG2169	Transcriptional regulator
ISD32_RS16885	COG2824	Alkylphosphonate utilization operon protein PhnA
ISD32_RS16890	COG2764	glyoxalase bleomycin resistance protein dioxygenase
ISD32_RS16895	COG2188	Transcriptional regulator
ISD32_RS16900	COG3624	Phosphonate C-P lyase system protein PhnG
ISD32_RS16905	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
ISD32_RS16910	COG3626	phosphonate metabolism
ISD32_RS16915	COG3627	carbon phosphorus lyase activity
ISD32_RS16920	COG4107	phosphonate C-P lyase system protein PhnK
ISD32_RS16925	COG4778	phosphonate C-P lyase system protein PhnL
ISD32_RS16930	COG3454	Phosphonate metabolism
ISD32_RS16940	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
ISD32_RS16950	COG0784	Response regulator, receiver
ISD32_RS16950	COG4191	Histidine kinase
ISD32_RS16955	COG1129	ABC transporter
ISD32_RS16960	COG1172	Belongs to the binding-protein-dependent transport system permease family
ISD32_RS16995	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
ISD32_RS17000	COG1301	dicarboxylic acid transport
ISD32_RS17015	COG3162	membrane
ISD32_RS17045	COG3539	Fimbrial protein
ISD32_RS17050	COG1346	cytolysis
ISD32_RS17055	COG1380	Effector of murein hydrolase LrgA
ISD32_RS17060	COG0583	DNA-binding transcription factor activity
ISD32_RS17065	COG0025	NhaP-type Na H and K H
ISD32_RS17070	COG2252	PERMEase
ISD32_RS17075	COG0625	glutathione transferase activity
ISD32_RS17080	COG0789	Transcriptional regulator
ISD32_RS17090	COG4943	cyclic-guanylate-specific phosphodiesterase activity
ISD32_RS17115	COG3842	ATPase activity
ISD32_RS17120	COG1234	tRNA 3'-trailer cleavage
ISD32_RS17125	COG1609	Transcriptional regulator
ISD32_RS17130	COG0483	inositol monophosphate 1-phosphatase activity
ISD32_RS17140	COG0583	DNA-binding transcription factor activity
ISD32_RS17150	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ISD32_RS17165	COG4771	TonB-dependent receptor
ISD32_RS17170	COG0741	lytic transglycosylase activity
ISD32_RS17175	COG0629	single-stranded DNA binding
ISD32_RS17185	COG2315	Protein conserved in bacteria
ISD32_RS17190	COG0432	Pfam Uncharacterised protein family UPF0047
ISD32_RS17205	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
ISD32_RS17210	COG0305	Participates in initiation and elongation during chromosome replication
ISD32_RS17225	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
ISD32_RS17235	COG0735	belongs to the Fur family
ISD32_RS17240	COG3237	CsbD-like
ISD32_RS17245	COG0534	Mate efflux family protein
ISD32_RS17255	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
ISD32_RS17315	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
ISD32_RS17325	COG0527	aspartate kinase activity
ISD32_RS17390	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
ISD32_RS17420	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
ISD32_RS17430	COG0456	acetyltransferase
ISD32_RS17460	COG0151	Belongs to the GarS family
ISD32_RS17470	COG4191	Histidine kinase
ISD32_RS17510	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
ISD32_RS17525	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
ISD32_RS17530	COG2104	thiamine diphosphate biosynthetic process
ISD32_RS17540	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
ISD32_RS17545	COG3706	GGDEF domain
ISD32_RS17555	COG1447	Phosphotransferase system cellobiose-specific component IIA
ISD32_RS17560	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
ISD32_RS17595	COG0250	Participates in transcription elongation, termination and antitermination
ISD32_RS17640	COG0812	UDP-N-acetylmuramate dehydrogenase activity
ISD32_RS17670	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
ISD32_RS17680	COG1739	Uncharacterized protein family UPF0029
ISD32_RS17720	COG0805	protein transport
ISD32_RS17740	COG3165	ubiquinone biosynthetic process from chorismate
ISD32_RS17760	COG0412	Dienelactone hydrolase
ISD32_RS17770	COG0583	DNA-binding transcription factor activity
ISD32_RS17775	COG0697	spore germination
ISD32_RS17780	COG0561	phosphatase activity
ISD32_RS17785	COG2267	carboxylic ester hydrolase activity
ISD32_RS17790	COG1280	lysine exporter protein (LysE YggA)
ISD32_RS17800	COG1280	lysine exporter protein (LysE YggA)
ISD32_RS17830	COG0210	DNA helicase
ISD32_RS17835	COG1011	Hydrolase
ISD32_RS17865	COG3072	Adenylate cyclase
ISD32_RS17880	COG2959	enzyme of heme biosynthesis
ISD32_RS17885	COG3071	HemY protein
ISD32_RS17930	COG2244	polysaccharide biosynthetic process
ISD32_RS17935	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
ISD32_RS17940	COG0456	acetyltransferase
ISD32_RS17945	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
ISD32_RS17950	COG1088	dTDP-glucose 4,6-dehydratase activity
ISD32_RS17955	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
ISD32_RS17960	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
ISD32_RS17970	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
ISD32_RS17975	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
ISD32_RS17980	COG3118	belongs to the thioredoxin family
ISD32_RS18005	COG1811	Na channel or pump
ISD32_RS18015	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
ISD32_RS18020	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
ISD32_RS18030	COG0583	DNA-binding transcription factor activity
ISD32_RS18035	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
ISD32_RS18045	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
ISD32_RS18050	COG3978	acetolactate synthase activity
ISD32_RS18070	COG3085	chromosome segregation
ISD32_RS18145	COG0583	DNA-binding transcription factor activity
ISD32_RS18160	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
ISD32_RS18175	COG3443	Belongs to the bacterial solute-binding protein 9 family
ISD32_RS18180	COG2207	Transcriptional regulator
ISD32_RS18190	COG0371	Dehydrogenase
ISD32_RS18200	COG0583	DNA-binding transcription factor activity
ISD32_RS18210	COG0737	Belongs to the 5'-nucleotidase family
ISD32_RS18220	COG0527	aspartate kinase activity
ISD32_RS18220	COG0460	homoserine dehydrogenase
ISD32_RS18225	COG0626	cystathionine gamma-synthase activity
ISD32_RS18240	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
ISD32_RS18245	COG1609	Transcriptional regulator
ISD32_RS18250	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
ISD32_RS18265	COG1575	Belongs to the MenA family. Type 1 subfamily
ISD32_RS18285	COG3678	ATP-independent chaperone mediated protein folding
ISD32_RS18290	COG0745	RESPONSE REGULATOR receiver
ISD32_RS18295	COG2205	protein histidine kinase activity
ISD32_RS18300	COG2258	MOSC domain
ISD32_RS18305	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
ISD32_RS18345	COG1129	ABC transporter
ISD32_RS18350	COG1172	Belongs to the binding-protein-dependent transport system permease family
ISD32_RS18355	COG1172	Belongs to the binding-protein-dependent transport system permease family
ISD32_RS18360	COG1454	alcohol dehydrogenase
ISD32_RS18370	COG2211	Major facilitator Superfamily
ISD32_RS18430	COG0205	6-phosphofructokinase activity
ISD32_RS18450	COG0437	4 iron, 4 sulfur cluster binding
ISD32_RS18455	COG2864	formate dehydrogenase
ISD32_RS18470	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
ISD32_RS18475	COG0657	acetylesterase activity
ISD32_RS18480	COG0456	acetyltransferase
ISD32_RS18495	COG1011	Hydrolase
ISD32_RS18510	COG3852	Histidine kinase
ISD32_RS18525	COG0635	Involved in the biosynthesis of porphyrin-containing compound
ISD32_RS18545	COG0204	Acyl-transferase
ISD32_RS18555	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
ISD32_RS18560	COG3084	Protein conserved in bacteria
ISD32_RS18570	COG1763	Mo-molybdopterin cofactor biosynthetic process
ISD32_RS18595	COG2186	Transcriptional regulator
ISD32_RS18600	COG0477	Major facilitator Superfamily
ISD32_RS18605	COG1609	Transcriptional regulator
ISD32_RS18610	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ISD32_RS18620	COG1172	Belongs to the binding-protein-dependent transport system permease family
ISD32_RS18625	COG1129	ABC transporter
ISD32_RS18655	COG1522	sequence-specific DNA binding
ISD32_RS18660	COG0716	FMN binding
ISD32_RS18675	COG3312	ion transport
ISD32_RS18725	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
ISD32_RS18730	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
ISD32_RS18735	COG0573	inorganic phosphate transmembrane transporter activity
ISD32_RS18740	COG0581	inorganic phosphate transmembrane transporter activity
ISD32_RS18745	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
ISD32_RS18750	COG0704	Plays a role in the regulation of phosphate uptake
ISD32_RS18760	COG2382	esterase
ISD32_RS18765	COG0363	glucosamine-6-phosphate deaminase activity
ISD32_RS18770	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ISD32_RS18775	COG2252	PERMEase
ISD32_RS18780	COG0431	NADPH-dependent FMN reductase
ISD32_RS18785	COG2091	lysine biosynthetic process via aminoadipic acid
ISD32_RS18815	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
ISD32_RS18850	COG0561	phosphatase activity
ISD32_RS18865	COG0823	Involved in the tonB-independent uptake of proteins
ISD32_RS18870	COG5645	(Lipo)protein
ISD32_RS18885	COG3645	SOS response
ISD32_RS18895	COG2188	Transcriptional regulator
ISD32_RS18910	COG2149	membrane
ISD32_RS18920	COG0641	radical SAM
ISD32_RS18930	COG2610	gluconate transmembrane transporter activity
ISD32_RS18940	COG0583	DNA-binding transcription factor activity
ISD32_RS18945	COG2814	Major facilitator Superfamily
ISD32_RS18975	COG0028	Belongs to the TPP enzyme family
ISD32_RS18980	COG0440	acetolactate synthase activity
ISD32_RS18985	COG2197	response regulator
ISD32_RS18995	COG2271	Major facilitator Superfamily
ISD32_RS19025	COG4580	involved in the transport of maltose and maltodextrins
ISD32_RS19030	COG1447	Phosphotransferase system cellobiose-specific component IIA
ISD32_RS19035	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
ISD32_RS19035	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
ISD32_RS19045	COG1609	Transcriptional regulator
ISD32_RS19055	COG3384	dioxygenase
ISD32_RS19060	COG0583	DNA-binding transcription factor activity
ISD32_RS19065	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
ISD32_RS19070	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
ISD32_RS19075	COG2828	Protein conserved in bacteria
ISD32_RS19090	COG0697	spore germination
ISD32_RS19095	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ISD32_RS19095	COG1263	PTS System
ISD32_RS19105	COG2814	Major facilitator Superfamily
ISD32_RS19115	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ISD32_RS19140	COG1309	transcriptional regulator
ISD32_RS19150	COG0583	DNA-binding transcription factor activity
ISD32_RS19175	COG1464	Belongs to the NlpA lipoprotein family
ISD32_RS19190	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
ISD32_RS19200	COG1064	alcohol dehydrogenase
ISD32_RS19230	COG2211	Major facilitator Superfamily
ISD32_RS19235	COG1501	Belongs to the glycosyl hydrolase 31 family
ISD32_RS19245	COG1486	melibiose metabolic process
ISD32_RS19250	COG1263	PTS System
ISD32_RS19250	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ISD32_RS19255	COG2982	Protein involved in outer membrane biogenesis
ISD32_RS19260	COG2233	PERMEase
ISD32_RS19265	COG0786	glutamate:sodium symporter activity
ISD32_RS19280	COG3074	FtsZ-dependent cytokinesis
ISD32_RS19285	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
ISD32_RS19310	COG3152	Membrane
ISD32_RS19320	COG1494	fructose-1,6-bisphosphatase
ISD32_RS19325	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
ISD32_RS19330	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ISD32_RS19335	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
ISD32_RS19355	COG2860	membrane
ISD32_RS19365	COG1561	YicC-like family, N-terminal region
ISD32_RS19380	COG1131	(ABC) transporter
ISD32_RS19385	COG0842	Transport permease protein
ISD32_RS19410	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
ISD32_RS19420	COG0227	Belongs to the bacterial ribosomal protein bL28 family
ISD32_RS19430	COG4245	von Willebrand factor, type A
ISD32_RS19465	COG1519	Transferase
ISD32_RS19470	COG1216	Glycosyl transferase, family 2
ISD32_RS19475	COG0438	transferase activity, transferring glycosyl groups
ISD32_RS19485	COG0859	PFAM glycosyl transferase family 9
ISD32_RS19510	COG0859	PFAM glycosyl transferase family 9
ISD32_RS19525	COG0156	8-amino-7-oxononanoate synthase activity
ISD32_RS19535	COG0463	Glycosyl transferase, family 2
ISD32_RS19540	COG2861	carbohydrate metabolic process
ISD32_RS19545	COG4942	peptidase
ISD32_RS19555	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
ISD32_RS19560	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
ISD32_RS19580	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
ISD32_RS19590	COG2186	Transcriptional regulator
ISD32_RS19610	COG3722	fumarate hydratase activity
ISD32_RS19630	COG1566	PFAM secretion protein HlyD family protein
ISD32_RS19635	COG0625	glutathione transferase activity
ISD32_RS19645	COG3276	selenocysteine insertion sequence binding
ISD32_RS19650	COG0235	Class ii aldolase
ISD32_RS19655	COG3623	hexulose-6-phosphate isomerase
ISD32_RS19660	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
ISD32_RS19665	COG1070	Carbohydrate kinase
ISD32_RS19670	COG2271	Major facilitator Superfamily
ISD32_RS19680	COG2731	YhcH YjgK YiaL family protein
ISD32_RS19690	COG1414	Transcriptional regulator
ISD32_RS19695	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
ISD32_RS19700	COG3977	Valine--pyruvate aminotransferase
ISD32_RS19705	COG0366	Alpha amylase catalytic
ISD32_RS19710	COG2992	FlgJ-related protein
ISD32_RS19715	COG1609	Transcriptional regulator
ISD32_RS19715	COG2207	Transcriptional regulator
ISD32_RS19720	COG4214	carbohydrate transport
ISD32_RS19730	COG4213	ABC transporter substrate-binding protein
ISD32_RS19745	COG4682	membrane
ISD32_RS19750	COG4682	membrane
ISD32_RS19755	COG3274	enterobacterial common antigen metabolic process
ISD32_RS19780	COG0488	(ABC) transporter
ISD32_RS19785	COG1278	Cold shock
ISD32_RS19790	COG2944	sequence-specific DNA binding
ISD32_RS19795	COG2814	Major facilitator Superfamily
ISD32_RS19815	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ISD32_RS19825	COG1609	Transcriptional regulator
ISD32_RS19830	COG2885	chlorophyll binding
ISD32_RS19835	COG0243	molybdopterin cofactor binding
ISD32_RS19840	COG0456	acetyltransferase
ISD32_RS19845	COG2818	Glycosylase
ISD32_RS19850	COG5571	outer membrane autotransporter
ISD32_RS19855	COG2223	nitrite transmembrane transporter activity
ISD32_RS19885	COG0747	negative chemotaxis
ISD32_RS19890	COG0601	transmembrane transport
ISD32_RS19895	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ISD32_RS19900	COG0444	Belongs to the ABC transporter superfamily
ISD32_RS19905	COG4608	Belongs to the ABC transporter superfamily
ISD32_RS19920	COG2894	cell division
ISD32_RS19930	COG1215	transferase activity, transferring glycosyl groups
ISD32_RS19935	COG0457	Tetratricopeptide repeat
ISD32_RS19950	COG2194	sulfuric ester hydrolase activity
ISD32_RS19980	COG1215	transferase activity, transferring glycosyl groups
ISD32_RS19985	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
ISD32_RS19990	COG3118	belongs to the thioredoxin family
ISD32_RS19990	COG0457	Tetratricopeptide repeat
ISD32_RS19995	COG2200	EAL domain
ISD32_RS19995	COG2199	diguanylate cyclase activity
ISD32_RS20005	COG0612	Peptidase, M16
ISD32_RS20015	COG2982	Protein involved in outer membrane biogenesis
ISD32_RS20020	COG0477	Major facilitator Superfamily
ISD32_RS20025	COG1295	ribonuclease BN
ISD32_RS20030	COG0583	DNA-binding transcription factor activity
ISD32_RS20035	COG1028	Short-chain dehydrogenase reductase Sdr
ISD32_RS20040	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
ISD32_RS20050	COG1454	alcohol dehydrogenase
ISD32_RS20060	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ISD32_RS20065	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
ISD32_RS20070	COG0671	phosphoesterase, PA-phosphatase related
ISD32_RS20090	COG0589	response to stress
ISD32_RS20100	COG0306	phosphate transporter
ISD32_RS20105	COG2081	HI0933 family
ISD32_RS20110	COG2204	response regulator
ISD32_RS20115	COG3964	amidohydrolase
ISD32_RS20120	COG0471	metal ion transport
ISD32_RS20125	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
ISD32_RS20130	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
ISD32_RS20140	COG2239	Acts as a magnesium transporter
ISD32_RS20160	COG1124	(ABC) transporter
ISD32_RS20170	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ISD32_RS20175	COG0601	transmembrane transport
ISD32_RS20180	COG0747	negative chemotaxis
ISD32_RS20190	COG3479	Phenolic acid decarboxylase
ISD32_RS20230	COG0628	permease
ISD32_RS20235	COG0477	Major facilitator Superfamily
ISD32_RS20245	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
ISD32_RS20260	COG3714	YhhN family
ISD32_RS20270	COG3776	membrane
ISD32_RS20275	COG0742	ribosomal rna small subunit methyltransferase
ISD32_RS20280	COG0552	protein localization to endoplasmic reticulum
ISD32_RS20285	COG2884	Cell division ATP-binding protein ftsE
ISD32_RS20290	COG2177	Part of the ABC transporter FtsEX involved in
ISD32_RS20305	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
ISD32_RS20315	COG0683	leucine binding
ISD32_RS20325	COG0683	leucine binding
ISD32_RS20330	COG0559	Belongs to the binding-protein-dependent transport system permease family
ISD32_RS20380	COG0584	glycerophosphoryl diester phosphodiesterase
ISD32_RS20390	COG0405	Gamma-glutamyltransferase
ISD32_RS20395	COG1247	-acetyltransferase
ISD32_RS20405	COG0673	inositol 2-dehydrogenase activity
ISD32_RS20410	COG1741	Belongs to the pirin family
ISD32_RS20415	COG1609	Transcriptional regulator
ISD32_RS20420	COG3265	gluconokinase activity
ISD32_RS20425	COG2610	gluconate transmembrane transporter activity
ISD32_RS20435	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
ISD32_RS20460	COG0058	SHG alpha-glucan phosphorylase activity
ISD32_RS20475	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
ISD32_RS20490	COG1349	DNA-binding transcription factor activity
ISD32_RS20505	COG0058	SHG alpha-glucan phosphorylase activity
ISD32_RS20510	COG1640	4-alpha-glucanotransferase
ISD32_RS20515	COG2610	gluconate transmembrane transporter activity
ISD32_RS20525	COG1040	competence protein
ISD32_RS20550	COG1918	ferrous iron import across plasma membrane
ISD32_RS20555	COG2183	response to ionizing radiation
ISD32_RS20560	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
ISD32_RS20585	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
ISD32_RS20590	COG1011	Hydrolase
ISD32_RS20600	COG0494	nUDIX hydrolase
ISD32_RS20605	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
ISD32_RS20630	COG4796	Type ii and iii secretion system protein
ISD32_RS20645	COG3266	domain, Protein
ISD32_RS20650	COG0338	D12 class N6 adenine-specific DNA methyltransferase
ISD32_RS20655	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
ISD32_RS20680	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
ISD32_RS20685	COG0402	S-adenosylhomocysteine deaminase activity
ISD32_RS20690	COG0738	Major facilitator superfamily
ISD32_RS20715	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
ISD32_RS20720	COG1289	transmembrane transporter activity
ISD32_RS20730	COG1765	OsmC-like protein
ISD32_RS20735	COG3954	Phosphoribulokinase
ISD32_RS20745	COG0429	hydrolase of the alpha beta-hydrolase fold
ISD32_RS20750	COG0488	(ABC) transporter
ISD32_RS20765	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
ISD32_RS20770	COG1047	Peptidyl-prolyl cis-trans
ISD32_RS20780	COG0545	Peptidyl-prolyl cis-trans isomerase
ISD32_RS20785	COG2964	Protein conserved in bacteria
ISD32_RS20845	COG0051	transcription antitermination factor activity, RNA binding
ISD32_RS20870	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
ISD32_RS20885	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
ISD32_RS20950	COG0201	protein transport
ISD32_RS20965	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
ISD32_RS20975	COG0202	RNA polymerase activity
ISD32_RS20990	COG0789	Transcriptional regulator
ISD32_RS20995	COG3036	rescue of stalled ribosome
ISD32_RS21025	COG0758	DNA mediated transformation
ISD32_RS21035	COG0551	DNA topoisomerase type I activity
ISD32_RS21055	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
ISD32_RS21090	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ISD32_RS21095	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ISD32_RS21100	COG1309	transcriptional regulator
ISD32_RS21120	COG4145	pantothenate transmembrane transporter activity
ISD32_RS21125	COG3924	membrane
ISD32_RS21130	COG0439	Biotin carboxylase
ISD32_RS21135	COG0511	ligase activity, forming carbon-carbon bonds
ISD32_RS21160	COG2199	diguanylate cyclase activity
ISD32_RS21160	COG2200	EAL domain
ISD32_RS21165	COG1077	Cell shape determining protein MreB Mrl
ISD32_RS21170	COG1792	Involved in formation and maintenance of cell shape
ISD32_RS21175	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
ISD32_RS21185	COG1530	ribonuclease E activity
ISD32_RS21190	COG3164	Protein of unknown function
ISD32_RS21195	COG0312	modulator of DNA gyrase
ISD32_RS21200	COG0583	DNA-binding transcription factor activity
ISD32_RS21215	COG1289	transmembrane transporter activity
ISD32_RS21220	COG2732	(Barnase) inhibitor
ISD32_RS21245	COG1802	Transcriptional regulator
ISD32_RS21255	COG0471	metal ion transport
ISD32_RS21260	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
ISD32_RS21265	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
ISD32_RS21290	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ISD32_RS21295	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ISD32_RS21300	COG3105	Protein conserved in bacteria
ISD32_RS21305	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
ISD32_RS21325	COG0625	glutathione transferase activity
ISD32_RS21330	COG2969	positive regulation of protein catabolic process
ISD32_RS21340	COG0493	'glutamate synthase
ISD32_RS21345	COG0067	glutamate synthase
ISD32_RS21345	COG0069	glutamate synthase activity
ISD32_RS21345	COG0070	glutamate synthase
ISD32_RS21350	COG1242	4 iron, 4 sulfur cluster binding
ISD32_RS21355	COG2271	Major facilitator Superfamily
ISD32_RS21360	COG1063	alcohol dehydrogenase
ISD32_RS21365	COG1312	Catalyzes the dehydration of D-mannonate
ISD32_RS21370	COG0784	Response regulator, receiver
ISD32_RS21370	COG2198	Histidine kinase
ISD32_RS21370	COG5002	protein histidine kinase activity
ISD32_RS21375	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
ISD32_RS21380	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
ISD32_RS21385	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
ISD32_RS21395	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
ISD32_RS21400	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
ISD32_RS21405	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
ISD32_RS21410	COG1137	ATPase activity
ISD32_RS21415	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
ISD32_RS21420	COG3117	lipopolysaccharide transmembrane transporter activity
ISD32_RS21425	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
ISD32_RS21435	COG0530	calcium, potassium:sodium antiporter activity
ISD32_RS21440	COG1127	ABC transporter
ISD32_RS21445	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
ISD32_RS21450	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
ISD32_RS21455	COG2854	intermembrane phospholipid transfer
ISD32_RS21460	COG3113	response to antibiotic
ISD32_RS21465	COG5007	Belongs to the BolA IbaG family
ISD32_RS21475	COG3423	Transcriptional regulator
ISD32_RS21480	COG0142	geranyltranstransferase activity
ISD32_RS21495	COG0697	spore germination
ISD32_RS21505	COG2027	D-alanyl-D-alanine carboxypeptidase
ISD32_RS21515	COG1534	Rna-binding protein
ISD32_RS21525	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ISD32_RS21530	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
ISD32_RS21540	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
ISD32_RS21580	COG0195	Participates in both transcription termination and antitermination
ISD32_RS21625	COG0814	amino acid
ISD32_RS21630	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ISD32_RS21635	COG0826	peptidase U32
ISD32_RS21640	COG0826	peptidase U32
ISD32_RS21645	COG3154	lipid carrier protein
ISD32_RS21650	COG3153	acetyltransferase
ISD32_RS21665	COG0693	protein deglycase activity
ISD32_RS21670	COG0702	epimerase
ISD32_RS21675	COG0701	Predicted permease
ISD32_RS21680	COG2823	Periplasmic or secreted lipoprotein
ISD32_RS21700	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
ISD32_RS21715	COG1063	alcohol dehydrogenase
ISD32_RS21720	COG3775	system Galactitol-specific IIC component
ISD32_RS21725	COG3414	Phosphotransferase system galactitol-specific IIB component
ISD32_RS21730	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
ISD32_RS21740	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
ISD32_RS21740	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
ISD32_RS21745	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ISD32_RS21745	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ISD32_RS21745	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
ISD32_RS21750	COG1105	Belongs to the carbohydrate kinase PfkB family
ISD32_RS21760	COG1349	DNA-binding transcription factor activity
ISD32_RS21765	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ISD32_RS21770	COG2721	sulfolactate sulfo-lyase activity
ISD32_RS21780	COG2084	Dehydrogenase
ISD32_RS21785	COG1929	Belongs to the glycerate kinase type-1 family
ISD32_RS21810	COG1741	Belongs to the pirin family
ISD32_RS21815	COG0583	DNA-binding transcription factor activity
ISD32_RS21820	COG3152	Membrane
ISD32_RS21825	COG0435	Glutathione S-transferase
ISD32_RS21830	COG2259	Doxx family
ISD32_RS21840	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
ISD32_RS21845	COG4575	ribosome binding
ISD32_RS21850	COG1422	Protein of unknown function (DUF1090)
ISD32_RS21860	COG0586	Pfam SNARE associated Golgi protein
ISD32_RS21865	COG2186	Transcriptional regulator
ISD32_RS21870	COG2271	Major facilitator Superfamily
ISD32_RS21880	COG2721	sulfolactate sulfo-lyase activity
ISD32_RS21895	COG0861	Integral membrane protein TerC family
ISD32_RS21900	COG0673	inositol 2-dehydrogenase activity
ISD32_RS21905	COG1451	nucleotide metabolic process
ISD32_RS21915	COG1902	pentaerythritol trinitrate reductase activity
ISD32_RS21915	COG0446	pyridine nucleotide-disulphide oxidoreductase
ISD32_RS21965	COG1695	Transcriptional regulator
ISD32_RS21970	COG2375	cellular response to nickel ion
ISD32_RS21985	COG1461	Dihydroxyacetone kinase
ISD32_RS21990	COG2376	Dihydroxyacetone kinase
ISD32_RS22060	COG3247	response to pH
ISD32_RS22070	COG2198	Histidine kinase
ISD32_RS22070	COG2205	protein histidine kinase activity
ISD32_RS22070	COG0784	Response regulator, receiver
ISD32_RS22070	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ISD32_RS22075	COG2197	response regulator
ISD32_RS22090	COG0426	domain, Protein
ISD32_RS22090	COG1773	rubredoxin
ISD32_RS22115	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
ISD32_RS22120	COG0358	DNA primase activity
ISD32_RS22125	COG0828	Belongs to the bacterial ribosomal protein bS21 family
ISD32_RS22180	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
ISD32_RS22195	COG4991	sh3 domain protein
ISD32_RS22200	COG3025	triphosphatase activity
ISD32_RS22225	COG2960	long-chain fatty acid transporting porin activity
ISD32_RS22240	COG3384	dioxygenase
ISD32_RS22245	COG0754	glutathionylspermidine amidase activity
ISD32_RS22260	COG0494	nUDIX hydrolase
ISD32_RS22265	COG3151	Protein conserved in bacteria
ISD32_RS22270	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
ISD32_RS22275	COG3150	esterase
ISD32_RS22285	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
ISD32_RS22290	COG2249	NAD(P)H dehydrogenase (quinone) activity
ISD32_RS22295	COG0642	Histidine kinase
ISD32_RS22305	COG3111	PFAM Bacterial OB fold (BOF) protein
ISD32_RS22310	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
ISD32_RS22315	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
ISD32_RS22320	COG0204	Acyl-transferase
ISD32_RS22325	COG2132	Multicopper oxidase
ISD32_RS22330	COG1032	radical SAM domain protein
ISD32_RS22335	COG0656	L-ascorbic acid biosynthetic process
ISD32_RS22340	COG1979	alcohol dehydrogenase
ISD32_RS22345	COG2207	Transcriptional regulator
ISD32_RS22350	COG0586	Pfam SNARE associated Golgi protein
ISD32_RS22355	COG0626	cystathionine gamma-synthase activity
ISD32_RS22365	COG0848	biopolymer transport protein
ISD32_RS22385	COG0625	glutathione transferase activity
ISD32_RS22400	COG0754	glutathionylspermidine amidase activity
ISD32_RS22405	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ISD32_RS22435	COG0626	cystathionine gamma-synthase activity
ISD32_RS22490	COG1811	Na channel or pump
ISD32_RS22495	COG1982	Orn Lys Arg decarboxylase major
ISD32_RS22500	COG2211	Major facilitator Superfamily
ISD32_RS22515	COG1194	a g-specific adenine glycosylase
ISD32_RS22525	COG3171	Protein conserved in bacteria
ISD32_RS22540	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
ISD32_RS22540	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
ISD32_RS22545	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
ISD32_RS22550	COG0635	Involved in the biosynthesis of porphyrin-containing compound
ISD32_RS22565	COG0762	integral membrane protein
ISD32_RS22570	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
ISD32_RS22575	COG2805	Type II/IV secretion system protein
ISD32_RS22595	COG0189	ligase activity
ISD32_RS22600	COG1385	rRNA (uridine-N3-)-methyltransferase activity
ISD32_RS22605	COG2356	endonuclease I
ISD32_RS22615	COG2814	Major facilitator Superfamily
ISD32_RS22650	COG0501	Belongs to the peptidase M48B family
ISD32_RS22655	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
ISD32_RS22670	COG0191	fructose-bisphosphate aldolase activity
ISD32_RS22675	COG0668	transmembrane transport
ISD32_RS22685	COG2968	Membrane
ISD32_RS22700	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
ISD32_RS22710	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
ISD32_RS22730	COG0006	proline dipeptidase activity
ISD32_RS22735	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ISD32_RS22740	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ISD32_RS22760	COG1028	Short-chain dehydrogenase reductase Sdr
ISD32_RS22765	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ISD32_RS22785	COG2723	6-phospho-beta-galactosidase activity
ISD32_RS22790	COG1737	Transcriptional regulator
ISD32_RS22800	COG1272	protein, Hemolysin III
ISD32_RS22810	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
ISD32_RS22820	COG0716	FMN binding
ISD32_RS22825	COG4974	Belongs to the 'phage' integrase family
ISD32_RS22835	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
ISD32_RS22855	COG4942	peptidase
ISD32_RS22865	COG2814	Major facilitator Superfamily
ISD32_RS22880	COG0667	Aldo Keto reductase
ISD32_RS22885	COG2249	NAD(P)H dehydrogenase (quinone) activity
ISD32_RS22920	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
ISD32_RS22925	COG1393	Belongs to the ArsC family
ISD32_RS22940	COG1538	Outer membrane efflux protein
ISD32_RS22945	COG1289	transmembrane transporter activity
ISD32_RS22960	COG3592	Divergent 4Fe-4S mono-cluster
ISD32_RS22965	COG2388	GCN5-related N-acetyl-transferase
ISD32_RS22975	COG3539	Fimbrial protein
ISD32_RS22980	COG3539	Fimbrial protein
ISD32_RS22985	COG3539	Fimbrial protein
ISD32_RS22990	COG3188	usher protein
ISD32_RS22995	COG3121	Chaperone
ISD32_RS23000	COG3539	Fimbrial protein
ISD32_RS23010	COG4974	Belongs to the 'phage' integrase family
ISD32_RS23015	COG0582	viral genome integration into host DNA
ISD32_RS23035	COG3121	Chaperone
ISD32_RS23040	COG3188	usher protein
ISD32_RS23050	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
ISD32_RS23055	COG1846	Transcriptional regulator
ISD32_RS23060	COG0697	spore germination
ISD32_RS23110	COG0667	Aldo Keto reductase
ISD32_RS23115	COG0814	amino acid
ISD32_RS23130	COG0183	Belongs to the thiolase family
ISD32_RS23140	COG0823	Involved in the tonB-independent uptake of proteins
ISD32_RS23145	COG1028	Short-chain dehydrogenase reductase Sdr
ISD32_RS23150	COG2814	Major facilitator Superfamily
ISD32_RS23185	COG3842	ATPase activity
ISD32_RS23190	COG0395	ABC-type sugar transport system, permease component
ISD32_RS23195	COG1175	transmembrane transport
ISD32_RS23200	COG1917	Cupin 2, conserved barrel domain protein
ISD32_RS23205	COG1794	racemase activity, acting on amino acids and derivatives
ISD32_RS23210	COG0583	DNA-binding transcription factor activity
ISD32_RS23220	COG1609	Transcriptional regulator
ISD32_RS23225	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
ISD32_RS23230	COG2723	6-phospho-beta-galactosidase activity
ISD32_RS23235	COG2186	Transcriptional regulator
ISD32_RS23245	COG1609	Transcriptional regulator
ISD32_RS23265	COG0667	Aldo Keto reductase
ISD32_RS23275	COG0861	Integral membrane protein TerC family
ISD32_RS23310	COG2165	general secretion pathway protein
ISD32_RS23315	COG4795	General secretion pathway protein
ISD32_RS23325	COG4967	type IV pilus modification protein PilV
ISD32_RS23330	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
ISD32_RS23335	COG1025	Belongs to the peptidase M16 family
ISD32_RS23340	COG1074	ATP-dependent DNA helicase activity
ISD32_RS23345	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
ISD32_RS23355	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
ISD32_RS23355	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
ISD32_RS23360	COG0860	N-Acetylmuramoyl-L-alanine amidase
ISD32_RS23365	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
ISD32_RS23395	COG4656	Part of a membrane complex involved in electron transport
ISD32_RS23400	COG1454	alcohol dehydrogenase
ISD32_RS23400	COG1012	belongs to the aldehyde dehydrogenase family
ISD32_RS23430	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
ISD32_RS23635	COG2885	chlorophyll binding
ISD32_RS23670	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
ISD32_RS23675	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
ISD32_RS23680	COG2166	iron-sulfur cluster assembly
ISD32_RS23685	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
ISD32_RS23695	COG0583	DNA-binding transcription factor activity
ISD32_RS23700	COG2363	Small membrane protein
ISD32_RS23710	COG1349	DNA-binding transcription factor activity
ISD32_RS23730	COG0738	Major facilitator superfamily
ISD32_RS23735	COG0235	Class ii aldolase
ISD32_RS23740	COG1454	alcohol dehydrogenase
ISD32_RS23760	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ISD32_RS23775	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
ISD32_RS23780	COG2011	ABC-type metal ion transport system permease component
ISD32_RS23785	COG1464	Belongs to the NlpA lipoprotein family
ISD32_RS23790	COG0477	Major facilitator Superfamily
ISD32_RS23800	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
ISD32_RS23805	COG1760	l-serine dehydratase
ISD32_RS23810	COG0814	amino acid
ISD32_RS23815	COG1611	Belongs to the LOG family
ISD32_RS23830	COG3098	single-species biofilm formation
ISD32_RS23835	COG0564	pseudouridine synthase activity
ISD32_RS23840	COG0716	FMN binding
ISD32_RS23845	COG2271	Major facilitator Superfamily
ISD32_RS23850	COG4948	Mandelate Racemase Muconate Lactonizing
ISD32_RS23855	COG4948	Mandelate Racemase Muconate Lactonizing
ISD32_RS23860	COG1929	Belongs to the glycerate kinase type-1 family
ISD32_RS23865	COG4999	Histidine kinase
ISD32_RS23865	COG3850	Histidine kinase
ISD32_RS23865	COG2205	protein histidine kinase activity
ISD32_RS23865	COG3437	response regulator, receiver
ISD32_RS23875	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
ISD32_RS23880	COG3956	TIGRFAM MazG family protein
ISD32_RS23900	COG0602	queuosine metabolic process
ISD32_RS23905	COG0720	synthase
ISD32_RS23940	COG1857	crispr-associated protein
ISD32_RS23955	COG1518	maintenance of DNA repeat elements
ISD32_RS23960	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
ISD32_RS23975	COG2234	aminopeptidase activity
ISD32_RS24035	COG4942	peptidase
ISD32_RS24035	COG1388	LysM domain
ISD32_RS24040	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
ISD32_RS24065	COG0163	prenyltransferase activity
ISD32_RS24070	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
ISD32_RS24110	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ISD32_RS24115	COG4558	Periplasmic binding protein
ISD32_RS24120	COG3720	iron ion transport
ISD32_RS24140	COG0679	Auxin Efflux Carrier
ISD32_RS24155	COG1108	ABC-type Mn2 Zn2 transport systems permease components
ISD32_RS24160	COG1108	ABC-type Mn2 Zn2 transport systems permease components
ISD32_RS24165	COG1121	(ABC) transporter
ISD32_RS24170	COG0803	Belongs to the bacterial solute-binding protein 9 family
ISD32_RS24175	COG1609	Transcriptional regulator
ISD32_RS24180	COG1940	carbohydrate kinase activity
ISD32_RS24185	COG1447	Phosphotransferase system cellobiose-specific component IIA
ISD32_RS24190	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
ISD32_RS24195	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
ISD32_RS24200	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
ISD32_RS24205	COG4580	involved in the transport of maltose and maltodextrins
ISD32_RS24215	COG2723	6-phospho-beta-galactosidase activity
ISD32_RS24225	COG0309	Hydrogenase expression formation protein (HypE)
ISD32_RS24230	COG0409	Hydrogenase expression formation protein
ISD32_RS24235	COG0298	carbon dioxide binding
ISD32_RS24240	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
ISD32_RS24255	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
ISD32_RS24260	COG0651	ATP synthesis coupled electron transport
ISD32_RS24265	COG0650	Formate hydrogenlyase subunit 4
ISD32_RS24270	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
ISD32_RS24270	COG3261	NADH dehydrogenase
ISD32_RS24275	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ISD32_RS24280	COG3260	NADH ubiquinone oxidoreductase 20
ISD32_RS24290	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
ISD32_RS24300	COG2723	6-phospho-beta-galactosidase activity
ISD32_RS24305	COG1263	PTS System
ISD32_RS24305	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ISD32_RS24310	COG1609	Transcriptional regulator
ISD32_RS24315	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
ISD32_RS24320	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
ISD32_RS24325	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
ISD32_RS24335	COG1414	Transcriptional regulator
ISD32_RS24340	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
ISD32_RS24345	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
ISD32_RS24370	COG1349	DNA-binding transcription factor activity
ISD32_RS24375	COG4578	phosphoenolpyruvate-dependent sugar phosphotransferase system
ISD32_RS24380	COG1028	Short-chain dehydrogenase reductase Sdr
ISD32_RS24390	COG3732	PTS system glucitol sorbitol-specific
ISD32_RS24395	COG3730	PTS system glucitol sorbitol-specific
ISD32_RS24400	COG2951	lytic endotransglycosylase activity
ISD32_RS24405	COG1121	(ABC) transporter
ISD32_RS24410	COG1108	ABC-type Mn2 Zn2 transport systems permease components
ISD32_RS24415	COG0803	Belongs to the bacterial solute-binding protein 9 family
ISD32_RS24420	COG1546	Belongs to the CinA family
ISD32_RS24440	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
ISD32_RS24470	COG2823	Periplasmic or secreted lipoprotein
ISD32_RS24475	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ISD32_RS24480	COG1238	metal cluster binding
ISD32_RS24500	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
ISD32_RS24505	COG2814	Major facilitator Superfamily
ISD32_RS24510	COG1566	PFAM secretion protein HlyD family protein
ISD32_RS24515	COG1846	Transcriptional regulator
ISD32_RS24525	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
ISD32_RS24535	COG4176	ABC-type proline glycine betaine transport system permease component
ISD32_RS24550	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ISD32_RS24560	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
ISD32_RS24565	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
ISD32_RS24575	COG4575	ribosome binding
ISD32_RS24605	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
ISD32_RS24610	COG0640	Transcriptional regulator
ISD32_RS24620	COG0583	DNA-binding transcription factor activity
ISD32_RS24625	COG0671	phosphoesterase, PA-phosphatase related
ISD32_RS24630	COG3284	Transcriptional regulator
ISD32_RS24640	COG3539	Fimbrial protein
ISD32_RS24645	COG3121	Chaperone
ISD32_RS24680	COG1028	Short-chain dehydrogenase reductase Sdr
ISD32_RS24690	COG0235	Class ii aldolase
ISD32_RS24695	COG1126	abc transporter atp-binding protein
ISD32_RS24700	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ISD32_RS24740	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ISD32_RS24745	COG2207	Transcriptional regulator
ISD32_RS24745	COG3708	Transcriptional regulator
ISD32_RS24775	COG0662	Cupin 2, conserved barrel domain protein
ISD32_RS24785	COG1028	Short-chain dehydrogenase reductase Sdr
ISD32_RS24840	COG0582	viral genome integration into host DNA
ISD32_RS24855	COG2867	negative regulation of translational initiation
ISD32_RS24870	COG0497	DNA recombination
ISD32_RS24885	COG4536	flavin adenine dinucleotide binding
ISD32_RS24890	COG4137	Cytochrome C assembly protein
ISD32_RS24895	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
ISD32_RS24930	COG2885	chlorophyll binding
ISD32_RS24935	COG2199	diguanylate cyclase activity
ISD32_RS24945	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
ISD32_RS24950	COG0287	Prephenate dehydrogenase
ISD32_RS24950	COG1605	Chorismate mutase
ISD32_RS24960	COG1605	Chorismate mutase
ISD32_RS24960	COG0077	Prephenate dehydratase
ISD32_RS24970	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
ISD32_RS24975	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ISD32_RS24990	COG0542	response to heat
ISD32_RS25015	COG0477	Major facilitator Superfamily
ISD32_RS25020	COG5544	Lipoprotein
ISD32_RS25025	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ISD32_RS25035	COG3148	PFAM DTW domain containing protein
ISD32_RS25040	COG3118	belongs to the thioredoxin family
ISD32_RS25045	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ISD32_RS25060	COG0513	Belongs to the DEAD box helicase family
ISD32_RS25070	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
ISD32_RS25085	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
ISD32_RS25090	COG3026	antisigma factor binding
ISD32_RS25095	COG3086	response to oxidative stress
ISD32_RS25105	COG0681	Belongs to the peptidase S26 family
ISD32_RS25125	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
ISD32_RS25135	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
ISD32_RS25140	COG1737	Transcriptional regulator
ISD32_RS25145	COG0560	Phosphoserine phosphatase
ISD32_RS25160	COG0047	phosphoribosylformylglycinamidine synthase activity
ISD32_RS25160	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
ISD32_RS25165	COG2205	protein histidine kinase activity
ISD32_RS25170	COG3170	Tfp pilus assembly protein FimV
ISD32_RS25175	COG2204	response regulator
ISD32_RS25180	COG0347	Belongs to the P(II) protein family
ISD32_RS25185	COG1017	nitric oxide dioxygenase activity
ISD32_RS25185	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
ISD32_RS25195	COG2259	Doxx family
ISD32_RS25200	COG2814	Major facilitator Superfamily
ISD32_RS25205	COG3711	transcriptional antiterminator
ISD32_RS25210	COG3683	transport system, periplasmic component
ISD32_RS25215	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
ISD32_RS25245	COG0822	iron-sulfur transferase activity
ISD32_RS25265	COG0633	Ferredoxin
ISD32_RS25270	COG2975	iron-sulfur cluster assembly
ISD32_RS25295	COG2897	thiosulfate sulfurtransferase activity
ISD32_RS25300	COG2373	Large extracellular alpha-helical protein
ISD32_RS25305	COG4953	penicillin-binding protein 1C
ISD32_RS25335	COG2976	Protein conserved in bacteria
ISD32_RS25355	COG1645	bacterial-type flagellum-dependent swarming motility
ISD32_RS25365	COG0516	GMP reductase activity
ISD32_RS25365	COG0517	IMP dehydrogenase activity
ISD32_RS25375	COG0582	viral genome integration into host DNA
ISD32_RS25405	COG5314	conjugation
ISD32_RS25465	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
ISD32_RS25475	COG2814	Major facilitator Superfamily
ISD32_RS25510	COG2200	EAL domain
ISD32_RS25525	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
ISD32_RS25540	COG2723	6-phospho-beta-galactosidase activity
ISD32_RS25550	COG2233	PERMEase
ISD32_RS25565	COG1393	Belongs to the ArsC family
ISD32_RS25570	COG4783	chaperone-mediated protein folding
ISD32_RS25580	COG0628	permease
ISD32_RS25585	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
ISD32_RS25590	COG2716	regulation of RNA biosynthetic process
ISD32_RS25600	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
ISD32_RS25610	COG2321	neutral zinc metallopeptidase
ISD32_RS25615	COG1444	tRNA N-acetyltransferase activity
ISD32_RS25620	COG0400	carboxylic ester hydrolase activity
ISD32_RS25635	COG1393	Belongs to the ArsC family
ISD32_RS25645	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ISD32_RS25650	COG0493	'glutamate synthase
ISD32_RS25650	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
ISD32_RS25660	COG5342	invasion associated locus B
ISD32_RS25665	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
ISD32_RS25670	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
ISD32_RS25680	COG4810	utilization protein
ISD32_RS25710	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
ISD32_RS25770	COG0860	N-Acetylmuramoyl-L-alanine amidase
ISD32_RS25790	COG2837	iron assimilation
ISD32_RS25800	COG4150	thiosulfate binding
ISD32_RS25805	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
ISD32_RS25810	COG4208	sulfate ABC transporter
ISD32_RS25815	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
ISD32_RS25825	COG4319	ketosteroid isomerase
ISD32_RS25860	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
ISD32_RS25880	COG3530	Putative quorum-sensing-regulated virulence factor
ISD32_RS25885	COG0385	Bile acid
ISD32_RS25890	COG0583	DNA-binding transcription factor activity
ISD32_RS25920	COG3415	Transposase
ISD32_RS25925	COG3415	Transposase
ISD32_RS25940	COG2200	EAL domain
ISD32_RS25940	COG2199	diguanylate cyclase activity
ISD32_RS25945	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
ISD32_RS25960	COG0667	Aldo Keto reductase
ISD32_RS25965	COG3961	Belongs to the TPP enzyme family
ISD32_RS25980	COG3279	Response regulator of the LytR AlgR family
ISD32_RS25985	COG3275	phosphorelay sensor kinase activity
ISD32_RS25995	COG0436	Aminotransferase
ISD32_RS26005	COG2807	transmembrane transport
ISD32_RS26010	COG0590	tRNA wobble adenosine to inosine editing
ISD32_RS26015	COG0583	DNA-binding transcription factor activity
ISD32_RS26035	COG2116	formate transmembrane transporter activity
ISD32_RS26040	COG2853	Lipoprotein
ISD32_RS26050	COG3691	Protein conserved in bacteria
ISD32_RS26065	COG2062	phosphohistidine phosphatase, SixA
ISD32_RS26090	COG0730	response to heat
ISD32_RS26095	COG3101	peptidyl-lysine hydroxylation
ISD32_RS26110	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
ISD32_RS26120	COG2188	Transcriptional regulator
ISD32_RS26130	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
ISD32_RS26135	COG1447	Phosphotransferase system cellobiose-specific component IIA
ISD32_RS26155	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
ISD32_RS26165	COG0586	Pfam SNARE associated Golgi protein
ISD32_RS26175	COG0285	dihydrofolate synthase activity
ISD32_RS26180	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
ISD32_RS26185	COG1286	toxin biosynthetic process
ISD32_RS26190	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
ISD32_RS26195	COG0163	prenyltransferase activity
ISD32_RS26220	COG4160	amino acid transport
ISD32_RS26225	COG4598	ABC transporter
ISD32_RS26240	COG1090	epimerase
ISD32_RS26245	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
ISD32_RS26250	COG0625	glutathione transferase activity
ISD32_RS26255	COG0625	glutathione transferase activity
ISD32_RS26260	COG0622	Phosphoesterase
ISD32_RS26265	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
ISD32_RS26290	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ISD32_RS26295	COG0471	metal ion transport
ISD32_RS26295	COG0490	domain, Protein
ISD32_RS26305	COG0436	Aminotransferase
ISD32_RS26310	COG0583	DNA-binding transcription factor activity
ISD32_RS26355	COG0839	Belongs to the complex I subunit 6 family
ISD32_RS26365	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
ISD32_RS26370	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ISD32_RS26385	COG2153	protein acetylation
ISD32_RS26390	COG1169	isochorismate synthase
ISD32_RS26415	COG0318	PFAM AMP-dependent synthetase and ligase
ISD32_RS26425	COG5464	transposase or invertase
ISD32_RS26440	COG1414	Transcriptional regulator
ISD32_RS26450	COG2271	Major facilitator Superfamily
ISD32_RS26460	COG0247	lactate metabolic process
ISD32_RS26470	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
ISD32_RS26475	COG2271	Major facilitator Superfamily
ISD32_RS26480	COG0584	glycerophosphoryl diester phosphodiesterase
ISD32_RS26485	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
ISD32_RS26520	COG0642	Histidine kinase
ISD32_RS26520	COG2198	Histidine kinase
ISD32_RS26535	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
ISD32_RS26535	COG2169	Transcriptional regulator
ISD32_RS26540	COG3145	DNA-N1-methyladenine dioxygenase activity
ISD32_RS26545	COG4615	Cyclic peptide transporter
ISD32_RS26550	COG2239	Acts as a magnesium transporter
ISD32_RS26555	COG0659	secondary active sulfate transmembrane transporter activity
ISD32_RS26570	COG0628	permease
ISD32_RS26585	COG1126	abc transporter atp-binding protein
ISD32_RS26590	COG0765	amino acid transport
ISD32_RS26595	COG0765	amino acid transport
ISD32_RS26610	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
ISD32_RS26635	COG1349	DNA-binding transcription factor activity
ISD32_RS26640	COG0494	nUDIX hydrolase
ISD32_RS26660	COG1061	Type III restriction enzyme res subunit
ISD32_RS26665	COG1187	pseudouridine synthase activity
ISD32_RS26670	COG2814	Major facilitator Superfamily
ISD32_RS26680	COG4172	Belongs to the ABC transporter superfamily
ISD32_RS26685	COG4239	(ABC) transporter, permease
ISD32_RS26690	COG4174	ABC transporter (Permease)
ISD32_RS26695	COG4166	transmembrane transport
ISD32_RS26700	COG2200	EAL domain
ISD32_RS26705	COG0791	NLP P60 protein
ISD32_RS26710	COG0671	phosphoesterase, PA-phosphatase related
ISD32_RS26715	COG0523	cobalamin synthesis protein
ISD32_RS26720	COG0246	Mannitol dehydrogenase
ISD32_RS26725	COG1312	Catalyzes the dehydration of D-mannonate
ISD32_RS26750	COG1566	PFAM secretion protein HlyD family protein
ISD32_RS26755	COG2814	Major facilitator Superfamily
ISD32_RS26760	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
ISD32_RS26760	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
ISD32_RS26765	COG1105	Belongs to the carbohydrate kinase PfkB family
ISD32_RS26770	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ISD32_RS26770	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ISD32_RS26770	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
ISD32_RS26780	COG2855	membrane
ISD32_RS26785	COG0583	DNA-binding transcription factor activity
ISD32_RS26790	COG0833	amino acid
ISD32_RS26795	COG4771	TonB-dependent receptor
ISD32_RS26810	COG2311	Membrane
ISD32_RS26825	COG1129	ABC transporter
ISD32_RS26845	COG2949	membrane
ISD32_RS26855	COG1346	cytolysis
ISD32_RS26865	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
ISD32_RS26870	COG3659	wide pore channel activity
ISD32_RS26885	COG2723	6-phospho-beta-galactosidase activity
ISD32_RS26895	COG1538	Outer membrane efflux protein
ISD32_RS26900	COG0586	Pfam SNARE associated Golgi protein
ISD32_RS26910	COG1686	Belongs to the peptidase S11 family
ISD32_RS26925	COG0277	FAD linked oxidase domain protein
ISD32_RS26930	COG1472	Belongs to the glycosyl hydrolase 3 family
ISD32_RS26935	COG1732	Glycine betaine
ISD32_RS26940	COG1174	glycine betaine transport
ISD32_RS26945	COG1125	glycine betaine transport
ISD32_RS26950	COG1174	glycine betaine transport
ISD32_RS26960	COG3275	phosphorelay sensor kinase activity
ISD32_RS26970	COG4807	Protein conserved in bacteria
ISD32_RS26985	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
ISD32_RS26990	COG2213	PTS system mannitol-specific
ISD32_RS26990	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
ISD32_RS26995	COG3414	Phosphotransferase system galactitol-specific IIB component
ISD32_RS27000	COG3775	system Galactitol-specific IIC component
ISD32_RS27005	COG0698	ribose 5-phosphate isomerase
ISD32_RS27010	COG1349	DNA-binding transcription factor activity
ISD32_RS27015	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
ISD32_RS27020	COG3414	Phosphotransferase system galactitol-specific IIB component
ISD32_RS27025	COG3775	system Galactitol-specific IIC component
ISD32_RS27030	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
ISD32_RS27035	COG1028	Short-chain dehydrogenase reductase Sdr
ISD32_RS27040	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
ISD32_RS27080	COG2801	Transposase and inactivated derivatives
ISD32_RS27090	COG2801	Transposase and inactivated derivatives
ISD32_RS27150	COG2223	nitrite transmembrane transporter activity
ISD32_RS27165	COG0800	Aldolase
ISD32_RS27170	COG3734	2-keto-3-deoxy-galactonokinase
ISD32_RS27175	COG2186	Transcriptional regulator
ISD32_RS27185	COG3381	protein complex oligomerization
ISD32_RS27195	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
ISD32_RS27200	COG0814	amino acid
ISD32_RS27205	COG1522	sequence-specific DNA binding
ISD32_RS27215	COG1794	racemase activity, acting on amino acids and derivatives
ISD32_RS27260	COG2207	Transcriptional regulator
ISD32_RS27260	COG3708	Transcriptional regulator
ISD32_RS27270	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ISD32_RS27280	COG0745	RESPONSE REGULATOR receiver
ISD32_RS27290	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
ISD32_RS27290	COG0456	acetyltransferase
ISD32_RS27400	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
ISD32_RS27405	COG0148	phosphopyruvate hydratase activity
ISD32_RS27415	COG1227	inorganic diphosphatase activity
ISD32_RS27505	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
ISD32_RS27535	COG0431	NADPH-dependent FMN reductase
ISD32_RS27830	COG0583	DNA-binding transcription factor activity
ISD32_RS27835	COG0129	dihydroxy-acid dehydratase activity
ISD32_RS27845	COG2801	Transposase and inactivated derivatives
ISD32_RS27875	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
ISD32_RS27900	COG1566	PFAM secretion protein HlyD family protein
ISD32_RS27905	COG2814	Major facilitator Superfamily
ISD32_RS27925	COG0583	DNA-binding transcription factor activity
ISD32_RS27930	COG1486	melibiose metabolic process
ISD32_RS27935	COG3118	belongs to the thioredoxin family
ISD32_RS27940	COG2207	Transcriptional regulator
ISD32_RS27945	COG1881	PFAM PEBP family protein
ISD32_RS27950	COG1902	pentaerythritol trinitrate reductase activity
ISD32_RS27960	COG1028	Short-chain dehydrogenase reductase Sdr