locus-tag	class	description
KLLA0_A00198g	COG1635	Involved in the biosynthesis of the thiazole moiety of thiamine. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur
KLLA0_A00220g	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
KLLA0_A00242g	COG1584	GPR1 FUN34 yaaH family protein
KLLA0_A00286g	COG1196	nuclear chromosome segregation
KLLA0_A00352g	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
KLLA0_A00374g	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
KLLA0_A00418g	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
KLLA0_A00484g	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
KLLA0_A00638g	COG5002	protein histidine kinase activity
KLLA0_A00638g	COG2205	protein histidine kinase activity
KLLA0_A00638g	COG0784	Response regulator, receiver
KLLA0_A00682g	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
KLLA0_A00957g	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
KLLA0_A01133g	COG0484	heat shock protein binding
KLLA0_A01452g	COG0488	(ABC) transporter
KLLA0_A01518g	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
KLLA0_A01848g	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KLLA0_A01947g	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
KLLA0_A01991g	COG1394	ATPase activity, coupled to movement of substances
KLLA0_A02035g	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
KLLA0_A02211g	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
KLLA0_A02233g	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
KLLA0_A02453g	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
KLLA0_A02607g	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
KLLA0_A02651g	COG0450	alkyl hydroperoxide reductase
KLLA0_A02673g	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
KLLA0_A03025g	COG0672	)-iron permease
KLLA0_A03069g	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
KLLA0_A03135g	COG0009	L-threonylcarbamoyladenylate synthase
KLLA0_A03223g	COG2814	Major facilitator Superfamily
KLLA0_A03245g	COG0220	tRNA (guanine-N7-)-methyltransferase activity
KLLA0_A03740g	COG1914	H( )-stimulated, divalent metal cation uptake system
KLLA0_A03982g	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
KLLA0_A04191g	COG0459	protein refolding
KLLA0_A04235g	COG1213	nucleotidyl transferase
KLLA0_A04587g	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
KLLA0_A04631g	COG0477	Major facilitator Superfamily
KLLA0_A04752g	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KLLA0_A04840g	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
KLLA0_A04862g	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
KLLA0_A04961g	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
KLLA0_A05324g	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
KLLA0_A05390g	COG0363	glucosamine-6-phosphate deaminase activity
KLLA0_A05478g	COG0045	succinate-CoA ligase (ADP-forming) activity
KLLA0_A05544g	COG0205	6-phosphofructokinase activity
KLLA0_A05863g	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
KLLA0_A06688g	COG0481	GTPase activity
KLLA0_A06732g	COG0142	geranyltranstransferase activity
KLLA0_A06798g	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
KLLA0_A06886g	COG0833	amino acid
KLLA0_A06930g	COG0833	amino acid
KLLA0_A06952g	COG0534	Mate efflux family protein
KLLA0_A07040g	COG0018	arginyl-trna synthetase
KLLA0_A07172g	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
KLLA0_A07733g	COG1643	Atp-dependent helicase
KLLA0_A07843g	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
KLLA0_A08316g	COG1252	NADH dehydrogenase
KLLA0_A08404g	COG0165	Argininosuccinate lyase
KLLA0_A08426g	COG0017	Asparaginyl-tRNA synthetase
KLLA0_A08448g	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
KLLA0_A08910g	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
KLLA0_A09031g	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
KLLA0_A09075g	COG1902	pentaerythritol trinitrate reductase activity
KLLA0_A09185g	COG0148	phosphopyruvate hydratase activity
KLLA0_A09339g	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
KLLA0_A09647g	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KLLA0_A09647g	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KLLA0_A09735g	COG0302	gtp cyclohydrolase
KLLA0_A09845g	COG0154	amidase activity
KLLA0_A09889g	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
KLLA0_A09955g	COG0156	8-amino-7-oxononanoate synthase activity
KLLA0_A10131g	COG5265	(ABC) transporter
KLLA0_A10307g	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
KLLA0_A10417g	COG1621	beta-fructofuranosidase activity
KLLA0_A10593g	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
KLLA0_A10813g	COG0833	amino acid
KLLA0_A10835g	COG0557	exoribonuclease II activity
KLLA0_A10857g	COG0488	(ABC) transporter
KLLA0_A10923g	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
KLLA0_A11011g	COG0126	phosphoglycerate kinase activity
KLLA0_A11110g	COG2814	Major facilitator Superfamily
KLLA0_A11176g	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
KLLA0_A11352g	COG1028	Short-chain dehydrogenase reductase Sdr
KLLA0_A11484g	COG0017	Asparaginyl-tRNA synthetase
KLLA0_A11660g	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
KLLA0_A11770g	COG0833	amino acid
KLLA0_A11814g	COG1185	polyribonucleotide nucleotidyltransferase activity
KLLA0_B00242g	COG0366	Alpha amylase catalytic
KLLA0_B00264g	COG2814	Major facilitator Superfamily
KLLA0_B00407g	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
KLLA0_B00539g	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
KLLA0_B00561g	COG1643	Atp-dependent helicase
KLLA0_B00737g	COG0037	tRNA processing
KLLA0_B00847g	COG0724	RNA recognition motif
KLLA0_B00869g	COG0267	Belongs to the bacterial ribosomal protein bL33 family
KLLA0_B01111g	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
KLLA0_B01265g	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
KLLA0_B01309g	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
KLLA0_B01397g	COG0277	FAD linked oxidase domain protein
KLLA0_B01628g	COG0450	alkyl hydroperoxide reductase
KLLA0_B01694g	COG0194	GDP metabolic process
KLLA0_B01738g	COG0025	NhaP-type Na H and K H
KLLA0_B01848g	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
KLLA0_B01892g	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
KLLA0_B01980g	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
KLLA0_B02134g	COG0352	thiamine-phosphate diphosphorylase activity
KLLA0_B02244g	COG0101	tRNA pseudouridine synthase activity
KLLA0_B02310g	COG0513	Belongs to the DEAD box helicase family
KLLA0_B02464g	COG0584	glycerophosphoryl diester phosphodiesterase
KLLA0_B02563g	COG4178	(ABC) transporter
KLLA0_B02717g	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
KLLA0_B02783g	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
KLLA0_B02959g	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KLLA0_B03069g	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KLLA0_B03234g	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KLLA0_B03355g	COG0538	isocitrate dehydrogenase activity
KLLA0_B03377g	COG0463	Glycosyl transferase, family 2
KLLA0_B03586g	COG2815	serine threonine protein kinase
KLLA0_B03586g	COG0515	serine threonine protein kinase
KLLA0_B03938g	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KLLA0_B04004g	COG2313	pseudouridylate synthase activity
KLLA0_B04378g	COG0626	cystathionine gamma-synthase activity
KLLA0_B04565g	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
KLLA0_B04774g	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KLLA0_B04774g	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KLLA0_B05137g	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
KLLA0_B05247g	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
KLLA0_B05577g	COG0085	RNA polymerase activity
KLLA0_B05863g	COG0596	Alpha beta hydrolase
KLLA0_B06094g	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KLLA0_B06303g	COG0085	RNA polymerase activity
KLLA0_B06523g	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KLLA0_B06556g	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
KLLA0_B06754g	COG0404	The glycine cleavage system catalyzes the degradation of glycine
KLLA0_B06776g	COG0833	amino acid
KLLA0_B06842g	COG0318	PFAM AMP-dependent synthetase and ligase
KLLA0_B07062g	COG0259	pyridoxamine-phosphate oxidase activity
KLLA0_B07205g	COG0515	serine threonine protein kinase
KLLA0_B07271g	COG0484	heat shock protein binding
KLLA0_B07557g	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
KLLA0_B07579g	COG0515	serine threonine protein kinase
KLLA0_B07579g	COG2815	serine threonine protein kinase
KLLA0_B07733g	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
KLLA0_B07843g	COG0443	Heat shock 70 kDa protein
KLLA0_B08063g	COG0047	phosphoribosylformylglycinamidine synthase activity
KLLA0_B08063g	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KLLA0_B08129g	COG1162	GTPase activity
KLLA0_B08239g	COG0539	negative regulation of cytoplasmic translation
KLLA0_B08371g	COG4221	oxidoreductase activity
KLLA0_B08437g	COG0590	tRNA wobble adenosine to inosine editing
KLLA0_B08800g	COG0154	amidase activity
KLLA0_B08932g	COG0423	glycine-tRNA ligase activity
KLLA0_B08998g	COG2895	sulfate adenylyltransferase (ATP) activity
KLLA0_B09152g	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
KLLA0_B09174g	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
KLLA0_B09240g	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
KLLA0_B09306g	COG0494	nUDIX hydrolase
KLLA0_B09504g	COG0316	Belongs to the HesB IscA family
KLLA0_B09526g	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
KLLA0_B09636g	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
KLLA0_B09658g	COG0667	Aldo Keto reductase
KLLA0_B09702g	COG1716	ATPase activity
KLLA0_B09702g	COG1131	(ABC) transporter
KLLA0_B09702g	COG0842	Transport permease protein
KLLA0_B09790g	COG0515	serine threonine protein kinase
KLLA0_B09790g	COG2815	serine threonine protein kinase
KLLA0_B09922g	COG0833	amino acid
KLLA0_B10175g	COG1657	PFAM Prenyltransferase squalene oxidase
KLLA0_B10472g	COG0724	RNA recognition motif
KLLA0_B10648g	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
KLLA0_B10692g	COG0175	sulfate reduction
KLLA0_B10868g	COG0367	asparagine synthase
KLLA0_B11033g	COG0004	ammonium transporteR
KLLA0_B11638g	COG1643	Atp-dependent helicase
KLLA0_B11924g	COG0515	serine threonine protein kinase
KLLA0_B11924g	COG2815	serine threonine protein kinase
KLLA0_B12012g	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
KLLA0_B12100g	COG0456	acetyltransferase
KLLA0_B12177g	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
KLLA0_B12199g	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
KLLA0_B12265g	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
KLLA0_B12375g	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
KLLA0_B12375g	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
KLLA0_B12397g	COG0339	signal peptide processing
KLLA0_B12463g	COG0285	dihydrofolate synthase activity
KLLA0_B12540g	COG1012	belongs to the aldehyde dehydrogenase family
KLLA0_B12584g	COG0028	Belongs to the TPP enzyme family
KLLA0_B12694g	COG0033	Phosphoglucomutase
KLLA0_B12716g	COG0515	serine threonine protein kinase
KLLA0_B12848g	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
KLLA0_B12958g	COG0328	RNA-DNA hybrid ribonuclease activity
KLLA0_B13112g	COG2815	serine threonine protein kinase
KLLA0_B13112g	COG0515	serine threonine protein kinase
KLLA0_B13321g	COG0529	Catalyzes the synthesis of activated sulfate
KLLA0_B13519g	COG0052	Belongs to the universal ribosomal protein uS2 family
KLLA0_B13739g	COG2255	four-way junction helicase activity
KLLA0_B13882g	COG0459	protein refolding
KLLA0_B13926g	COG0351	phosphomethylpyrimidine kinase
KLLA0_B13926g	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
KLLA0_B13926g	COG0352	thiamine-phosphate diphosphorylase activity
KLLA0_B13992g	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
KLLA0_B14058g	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
KLLA0_B14256g	COG1132	(ABC) transporter
KLLA0_B14278g	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
KLLA0_B14366g	COG0512	Glutamine amidotransferase of anthranilate synthase
KLLA0_B14476g	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
KLLA0_B14476g	COG1017	nitric oxide dioxygenase activity
KLLA0_B14685g	COG1113	amino acid transport
KLLA0_B14707g	COG0656	L-ascorbic acid biosynthetic process
KLLA0_B14729g	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
KLLA0_B14861g	COG2814	Major facilitator Superfamily
KLLA0_B14883g	COG3250	beta-galactosidase activity
KLLA0_C00440g	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
KLLA0_C00572g	COG0339	signal peptide processing
KLLA0_C00715g	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
KLLA0_C00737g	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
KLLA0_C01111g	COG3118	belongs to the thioredoxin family
KLLA0_C01452g	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
KLLA0_C01606g	COG0833	amino acid
KLLA0_C01650g	COG2815	serine threonine protein kinase
KLLA0_C01650g	COG0515	serine threonine protein kinase
KLLA0_C01694g	COG2132	Multicopper oxidase
KLLA0_C01826g	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
KLLA0_C01826g	COG0666	response to abiotic stimulus
KLLA0_C01991g	COG1132	(ABC) transporter
KLLA0_C02013g	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
KLLA0_C02035g	COG1819	glycosyl
KLLA0_C02167g	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KLLA0_C02343g	COG0833	amino acid
KLLA0_C02365g	COG0833	amino acid
KLLA0_C02761g	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KLLA0_C02783g	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
KLLA0_C02915g	COG1196	nuclear chromosome segregation
KLLA0_C02981g	COG0484	heat shock protein binding
KLLA0_C03025g	COG0215	cysteine-tRNA ligase activity
KLLA0_C03630g	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
KLLA0_C03674g	COG0210	DNA helicase
KLLA0_C03718g	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
KLLA0_C03718g	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
KLLA0_C03828g	COG2815	serine threonine protein kinase
KLLA0_C03828g	COG0515	serine threonine protein kinase
KLLA0_C03938g	COG0515	serine threonine protein kinase
KLLA0_C03938g	COG0457	Tetratricopeptide repeat
KLLA0_C03960g	COG1253	flavin adenine dinucleotide binding
KLLA0_C04037g	COG0137	argininosuccinate synthase activity
KLLA0_C04081g	COG0588	phosphoglycerate mutase activity
KLLA0_C04213g	COG2815	serine threonine protein kinase
KLLA0_C04213g	COG0515	serine threonine protein kinase
KLLA0_C04235g	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
KLLA0_C04301g	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
KLLA0_C04345g	COG0515	serine threonine protein kinase
KLLA0_C04345g	COG4991	sh3 domain protein
KLLA0_C04345g	COG3064	Membrane
KLLA0_C04477g	COG1716	ATPase activity
KLLA0_C04477g	COG1131	(ABC) transporter
KLLA0_C04477g	COG0842	Transport permease protein
KLLA0_C04576g	COG0513	Belongs to the DEAD box helicase family
KLLA0_C04598g	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
KLLA0_C04642g	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
KLLA0_C04818g	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
KLLA0_C04862g	COG0481	GTPase activity
KLLA0_C05214g	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
KLLA0_C05236g	COG0405	Gamma-glutamyltransferase
KLLA0_C05368g	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
KLLA0_C05522g	COG0724	RNA recognition motif
KLLA0_C05764g	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
KLLA0_C06270g	COG1841	ribosomal large subunit assembly
KLLA0_C06336g	COG1252	NADH dehydrogenase
KLLA0_C06380g	COG0193	aminoacyl-tRNA hydrolase activity
KLLA0_C06534g	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KLLA0_C06743g	COG2124	cytochrome p450
KLLA0_C06908g	COG0588	phosphoglycerate mutase activity
KLLA0_C07172g	COG0518	GMP synthase (glutamine-hydrolyzing) activity
KLLA0_C07172g	COG0519	Catalyzes the synthesis of GMP from XMP
KLLA0_C07260g	COG0484	heat shock protein binding
KLLA0_C07359g	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
KLLA0_C07535g	COG0515	serine threonine protein kinase
KLLA0_C07645g	COG0006	proline dipeptidase activity
KLLA0_C07777g	COG1012	belongs to the aldehyde dehydrogenase family
KLLA0_C07887g	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KLLA0_C07887g	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
KLLA0_C07997g	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
KLLA0_C08217g	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
KLLA0_C08239g	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
KLLA0_C08349g	COG0251	oxidation-reduction process
KLLA0_C08393g	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
KLLA0_C08448g	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
KLLA0_C08448g	COG0512	Glutamine amidotransferase of anthranilate synthase
KLLA0_C08525g	COG0515	serine threonine protein kinase
KLLA0_C08547g	COG4249	Peptidase C14 caspase catalytic subunit p20
KLLA0_C08547g	COG2319	Wd-40 repeat
KLLA0_C08635g	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
KLLA0_C08701g	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
KLLA0_C09240g	COG0167	dihydroorotate dehydrogenase activity
KLLA0_C09306g	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
KLLA0_C09548g	COG0109	protoheme IX farnesyltransferase activity
KLLA0_C09592g	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KLLA0_C09823g	COG0484	heat shock protein binding
KLLA0_C09911g	COG0417	DNA replication proofreading
KLLA0_C09966g	COG2897	thiosulfate sulfurtransferase activity
KLLA0_C10208g	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
KLLA0_C10296g	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
KLLA0_C10384g	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
KLLA0_C10549g	COG1012	belongs to the aldehyde dehydrogenase family
KLLA0_C10571g	COG0557	exoribonuclease II activity
KLLA0_C10714g	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
KLLA0_C10736g	COG1111	helicase
KLLA0_C10736g	COG1205	dead DEAH box helicase
KLLA0_C10857g	COG1063	alcohol dehydrogenase
KLLA0_C11099g	COG1185	polyribonucleotide nucleotidyltransferase activity
KLLA0_C11297g	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
KLLA0_C11319g	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
KLLA0_C11319g	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
KLLA0_C11451g	COG0459	protein refolding
KLLA0_C11803g	COG2351	hydroxyisourate hydrolase activity
KLLA0_C12133g	COG0200	Binds to the 23S rRNA
KLLA0_C12309g	COG2814	Major facilitator Superfamily
KLLA0_C12397g	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
KLLA0_C12694g	COG1028	Short-chain dehydrogenase reductase Sdr
KLLA0_C12991g	COG0644	oxidoreductase
KLLA0_C12991g	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
KLLA0_C13255g	COG0417	DNA replication proofreading
KLLA0_C13541g	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
KLLA0_C13838g	COG0187	DNA topoisomerase II activity
KLLA0_C14234g	COG1132	(ABC) transporter
KLLA0_C14256g	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
KLLA0_C14432g	COG0076	glutamate decarboxylase activity
KLLA0_C14520g	COG1222	aaa ATPase
KLLA0_C14652g	COG0443	Heat shock 70 kDa protein
KLLA0_C14949g	COG0738	Major facilitator superfamily
KLLA0_C15059g	COG0156	8-amino-7-oxononanoate synthase activity
KLLA0_C15125g	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
KLLA0_C15147g	COG0181	hydroxymethylbilane synthase activity
KLLA0_C15257g	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
KLLA0_C15433g	COG0513	Belongs to the DEAD box helicase family
KLLA0_C15873g	COG1113	amino acid transport
KLLA0_C15895g	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
KLLA0_C15983g	COG0736	holo-[acyl-carrier-protein] synthase activity
KLLA0_C16071g	COG0463	Glycosyl transferase, family 2
KLLA0_C16115g	COG0488	(ABC) transporter
KLLA0_C16137g	COG1546	Belongs to the CinA family
KLLA0_C16137g	COG1058	Belongs to the CinA family
KLLA0_C16423g	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
KLLA0_C16577g	COG0515	serine threonine protein kinase
KLLA0_C16621g	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
KLLA0_C17028g	COG0626	cystathionine gamma-synthase activity
KLLA0_C17314g	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
KLLA0_C17424g	COG0513	Belongs to the DEAD box helicase family
KLLA0_C17556g	COG1122	ATPase activity
KLLA0_C17578g	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
KLLA0_C17688g	COG0617	tRNA 3'-terminal CCA addition
KLLA0_C17732g	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
KLLA0_C17842g	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
KLLA0_C18051g	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
KLLA0_C18513g	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KLLA0_C18590g	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
KLLA0_C18887g	COG0673	inositol 2-dehydrogenase activity
KLLA0_C18909g	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KLLA0_C19085g	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KLLA0_C19360g	COG0167	dihydroorotate dehydrogenase activity
KLLA0_C19382g	COG1454	alcohol dehydrogenase
KLLA0_D00231g	COG0366	Alpha amylase catalytic
KLLA0_D00253g	COG2814	Major facilitator Superfamily
KLLA0_D00462g	COG0415	Belongs to the DNA photolyase family
KLLA0_D00594g	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
KLLA0_D00748g	COG1132	(ABC) transporter
KLLA0_D00902g	COG0114	fumarate hydratase activity
KLLA0_D01243g	COG1741	Belongs to the pirin family
KLLA0_D01551g	COG2040	homocysteine
KLLA0_D01573g	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KLLA0_D01771g	COG2226	methyltransferase
KLLA0_D01903g	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
KLLA0_D02134g	COG0156	8-amino-7-oxononanoate synthase activity
KLLA0_D02156g	COG1119	ATPase activity
KLLA0_D02288g	COG5277	cytoskeleton organization
KLLA0_D02508g	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
KLLA0_D02772g	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
KLLA0_D02794g	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
KLLA0_D02838g	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KLLA0_D02926g	COG0418	dihydroorotase activity
KLLA0_D02970g	COG2271	Major facilitator Superfamily
KLLA0_D03146g	COG2816	NAD+ diphosphatase activity
KLLA0_D03168g	COG0515	serine threonine protein kinase
KLLA0_D03190g	COG2815	serine threonine protein kinase
KLLA0_D03190g	COG0515	serine threonine protein kinase
KLLA0_D03212g	COG0222	ribosome binding
KLLA0_D03344g	COG0277	FAD linked oxidase domain protein
KLLA0_D03432g	COG1716	ATPase activity
KLLA0_D03432g	COG0842	Transport permease protein
KLLA0_D03432g	COG1131	(ABC) transporter
KLLA0_D03476g	COG1131	(ABC) transporter
KLLA0_D03476g	COG1716	ATPase activity
KLLA0_D03476g	COG0842	Transport permease protein
KLLA0_D03608g	COG0012	GTP binding
KLLA0_D03630g	COG1999	signal sequence binding
KLLA0_D03696g	COG0105	UTP biosynthetic process
KLLA0_D03839g	COG0017	Asparaginyl-tRNA synthetase
KLLA0_D03905g	COG0386	Belongs to the glutathione peroxidase family
KLLA0_D04037g	COG2873	o-acetylhomoserine
KLLA0_D04059g	COG1132	(ABC) transporter
KLLA0_D04224g	COG0443	Heat shock 70 kDa protein
KLLA0_D04356g	COG2233	PERMEase
KLLA0_D04378g	COG0217	transcriptional regulatory protein
KLLA0_D04444g	COG1053	succinate dehydrogenase
KLLA0_D04554g	COG0842	Transport permease protein
KLLA0_D04554g	COG1131	(ABC) transporter
KLLA0_D04554g	COG1716	ATPase activity
KLLA0_D04796g	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
KLLA0_D04818g	COG0484	heat shock protein binding
KLLA0_D04906g	COG0473	3-isopropylmalate dehydrogenase activity
KLLA0_D04928g	COG1104	cysteine desulfurase activity
KLLA0_D05379g	COG2814	Major facilitator Superfamily
KLLA0_D05467g	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
KLLA0_D05511g	COG1063	alcohol dehydrogenase
KLLA0_D06127g	COG1028	Short-chain dehydrogenase reductase Sdr
KLLA0_D06259g	COG0475	glutathione-regulated potassium exporter activity
KLLA0_D06402g	COG0484	heat shock protein binding
KLLA0_D06655g	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
KLLA0_D06897g	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
KLLA0_D06919g	COG0823	Involved in the tonB-independent uptake of proteins
KLLA0_D06919g	COG1506	peptidase
KLLA0_D07007g	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
KLLA0_D07161g	COG0822	iron-sulfur transferase activity
KLLA0_D07304g	COG2815	serine threonine protein kinase
KLLA0_D07304g	COG0515	serine threonine protein kinase
KLLA0_D07326g	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
KLLA0_D07348g	COG0515	serine threonine protein kinase
KLLA0_D07348g	COG2815	serine threonine protein kinase
KLLA0_D07502g	COG1196	nuclear chromosome segregation
KLLA0_D07656g	COG0484	heat shock protein binding
KLLA0_D07744g	COG0004	ammonium transporteR
KLLA0_D07766g	COG0004	ammonium transporteR
KLLA0_D07810g	COG0515	serine threonine protein kinase
KLLA0_D07898g	COG0481	GTPase activity
KLLA0_D08052g	COG0179	Fumarylacetoacetate (FAA) hydrolase
KLLA0_D08096g	COG0688	phosphatidylethanolamine metabolic process
KLLA0_D08206g	COG0724	RNA recognition motif
KLLA0_D08305g	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
KLLA0_D08437g	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
KLLA0_D08690g	COG1490	D-aminoacyl-tRNA deacylase activity
KLLA0_D08712g	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
KLLA0_D08811g	COG0110	maltose O-acetyltransferase activity
KLLA0_D09020g	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
KLLA0_D09350g	COG0459	protein refolding
KLLA0_D09504g	COG0513	Belongs to the DEAD box helicase family
KLLA0_D09559g	COG0443	Heat shock 70 kDa protein
KLLA0_D09581g	COG1914	H( )-stimulated, divalent metal cation uptake system
KLLA0_D09911g	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
KLLA0_D09999g	COG1012	belongs to the aldehyde dehydrogenase family
KLLA0_D10021g	COG1012	belongs to the aldehyde dehydrogenase family
KLLA0_D10109g	COG0656	L-ascorbic acid biosynthetic process
KLLA0_D10659g	COG0049	tRNA binding
KLLA0_D10703g	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
KLLA0_D10736g	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KLLA0_D10890g	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KLLA0_D11154g	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KLLA0_D11242g	COG2124	cytochrome p450
KLLA0_D11484g	COG0248	Ppx GppA phosphatase
KLLA0_D11660g	COG0753	catalase activity
KLLA0_D11792g	COG0724	RNA recognition motif
KLLA0_D11814g	COG0515	serine threonine protein kinase
KLLA0_D11858g	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
KLLA0_D12056g	COG0183	Belongs to the thiolase family
KLLA0_D12078g	COG3265	gluconokinase activity
KLLA0_D12100g	COG0515	serine threonine protein kinase
KLLA0_D12100g	COG2815	serine threonine protein kinase
KLLA0_D12188g	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
KLLA0_D12342g	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
KLLA0_D12474g	COG5398	heme oxygenase
KLLA0_D12496g	COG1793	dna ligase
KLLA0_D12562g	COG0227	Belongs to the bacterial ribosomal protein bL28 family
KLLA0_D12628g	COG0154	amidase activity
KLLA0_D12694g	COG0514	ATP-dependent DNA helicase (RecQ)
KLLA0_D12738g	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
KLLA0_D12738g	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
KLLA0_D12958g	COG0326	Molecular chaperone. Has ATPase activity
KLLA0_D13068g	COG0308	aminopeptidase N
KLLA0_D13310g	COG2814	Major facilitator Superfamily
KLLA0_D13310g	COG0477	Major facilitator Superfamily
KLLA0_D13354g	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
KLLA0_D13464g	COG0484	heat shock protein binding
KLLA0_D13552g	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
KLLA0_D13970g	COG0489	protein tyrosine kinase activity
KLLA0_D14201g	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
KLLA0_D14487g	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
KLLA0_D14685g	COG0753	catalase activity
KLLA0_D14905g	COG0515	serine threonine protein kinase
KLLA0_D14949g	COG0724	RNA recognition motif
KLLA0_D14971g	COG0525	valine-tRNA ligase activity
KLLA0_D15455g	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
KLLA0_D15521g	COG1028	Short-chain dehydrogenase reductase Sdr
KLLA0_D15895g	COG0307	riboflavin synthase, alpha
KLLA0_D15983g	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
KLLA0_D16005g	COG1196	nuclear chromosome segregation
KLLA0_D16148g	COG0107	imidazoleglycerol-phosphate synthase activity
KLLA0_D16170g	COG0202	RNA polymerase activity
KLLA0_D16522g	COG0508	dehydrogenase complex catalyzes the overall conversion of
KLLA0_D16830g	COG0833	amino acid
KLLA0_D17094g	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
KLLA0_D18095g	COG0612	Peptidase, M16
KLLA0_D18172g	COG0564	pseudouridine synthase activity
KLLA0_D18436g	COG0024	Methionine aminopeptidase
KLLA0_D18711g	COG0237	dephospho-CoA kinase activity
KLLA0_D18777g	COG0321	lipoyl(octanoyl) transferase activity
KLLA0_D19041g	COG0443	Heat shock 70 kDa protein
KLLA0_D19360g	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
KLLA0_D19426g	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
KLLA0_D19492g	COG0402	S-adenosylhomocysteine deaminase activity
KLLA0_D19602g	COG0484	heat shock protein binding
KLLA0_D19624g	COG0625	glutathione transferase activity
KLLA0_D19833g	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
KLLA0_D19833g	COG4624	Iron only hydrogenase large subunit, C-terminal domain
KLLA0_D19855g	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
KLLA0_D19929g	COG1063	alcohol dehydrogenase
KLLA0_D19933g	COG0300	oxidoreductase activity
KLLA0_D19941g	COG0477	Major facilitator Superfamily
KLLA0_D19953g	COG2814	Major facilitator Superfamily
KLLA0_E00221g	COG0798	PFAM Bile acid sodium symporter
KLLA0_E00287g	COG0477	Major facilitator Superfamily
KLLA0_E00287g	COG2814	Major facilitator Superfamily
KLLA0_E00309g	COG3119	arylsulfatase activity
KLLA0_E00529g	COG1132	(ABC) transporter
KLLA0_E00595g	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
KLLA0_E00617g	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
KLLA0_E00683g	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
KLLA0_E00925g	COG0706	membrane insertase activity
KLLA0_E01497g	COG0003	Pfam Anion-transporting ATPase
KLLA0_E01673g	COG4284	Utp--glucose-1-phosphate uridylyltransferase
KLLA0_E01761g	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
KLLA0_E01783g	COG2814	Major facilitator Superfamily
KLLA0_E01805g	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
KLLA0_E01959g	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
KLLA0_E01981g	COG0123	including yeast histone deacetylase and acetoin utilization protein
KLLA0_E02003g	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KLLA0_E02487g	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KLLA0_E02685g	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
KLLA0_E02707g	COG3961	Belongs to the TPP enzyme family
KLLA0_E02993g	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
KLLA0_E03037g	COG2814	Major facilitator Superfamily
KLLA0_E03103g	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
KLLA0_E03125g	COG0473	3-isopropylmalate dehydrogenase activity
KLLA0_E03235g	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
KLLA0_E03433g	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
KLLA0_E03565g	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KLLA0_E03609g	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
KLLA0_E03719g	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
KLLA0_E03719g	COG0517	IMP dehydrogenase activity
KLLA0_E03829g	COG2814	Major facilitator Superfamily
KLLA0_E04159g	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
KLLA0_E04181g	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KLLA0_E04181g	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KLLA0_E04247g	COG0515	serine threonine protein kinase
KLLA0_E04247g	COG2815	serine threonine protein kinase
KLLA0_E04379g	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KLLA0_E04423g	COG0484	heat shock protein binding
KLLA0_E04577g	COG4783	chaperone-mediated protein folding
KLLA0_E04731g	COG0659	secondary active sulfate transmembrane transporter activity
KLLA0_E05105g	COG1025	Belongs to the peptidase M16 family
KLLA0_E05325g	COG0495	leucyl-tRNA aminoacylation
KLLA0_E05391g	COG2365	Tyrosine phosphatase family
KLLA0_E05435g	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
KLLA0_E05545g	COG0504	CTP synthase activity
KLLA0_E05743g	COG0049	tRNA binding
KLLA0_E06381g	COG0124	histidyl-tRNA synthetase
KLLA0_E06447g	COG2815	serine threonine protein kinase
KLLA0_E06447g	COG0515	serine threonine protein kinase
KLLA0_E06667g	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
KLLA0_E06755g	COG2814	Major facilitator Superfamily
KLLA0_E07063g	COG0738	Major facilitator superfamily
KLLA0_E07173g	COG1605	Chorismate mutase
KLLA0_E07173g	COG0077	Prephenate dehydratase
KLLA0_E07525g	COG0039	L-malate dehydrogenase activity
KLLA0_E07569g	COG0191	fructose-bisphosphate aldolase activity
KLLA0_E07657g	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
KLLA0_E07899g	COG0484	heat shock protein binding
KLLA0_E08053g	COG0563	adenylate kinase activity
KLLA0_E08339g	COG0473	3-isopropylmalate dehydrogenase activity
KLLA0_E08361g	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
KLLA0_E08361g	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
KLLA0_E08405g	COG0515	serine threonine protein kinase
KLLA0_E08405g	COG2815	serine threonine protein kinase
KLLA0_E08845g	COG1965	Belongs to the frataxin family
KLLA0_E08999g	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
KLLA0_E08999g	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
KLLA0_E09021g	COG2814	Major facilitator Superfamily
KLLA0_E09065g	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
KLLA0_E09109g	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
KLLA0_E09197g	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KLLA0_E09307g	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
KLLA0_E09373g	COG0596	Alpha beta hydrolase
KLLA0_E09571g	COG2271	Major facilitator Superfamily
KLLA0_E09791g	COG0508	dehydrogenase complex catalyzes the overall conversion of
KLLA0_E09835g	COG2046	Belongs to the sulfate adenylyltransferase family
KLLA0_E09835g	COG0529	Catalyzes the synthesis of activated sulfate
KLLA0_E09857g	COG1028	Short-chain dehydrogenase reductase Sdr
KLLA0_E10385g	COG1612	heme a metabolic process
KLLA0_E10407g	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
KLLA0_E10583g	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
KLLA0_E10649g	COG0133	tryptophan synthase activity
KLLA0_E11089g	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
KLLA0_E11265g	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
KLLA0_E11551g	COG0083	homoserine kinase activity
KLLA0_E11573g	COG0612	Peptidase, M16
KLLA0_E11859g	COG0588	phosphoglycerate mutase activity
KLLA0_E11881g	COG1584	GPR1 FUN34 yaaH family protein
KLLA0_E12145g	COG0515	serine threonine protein kinase
KLLA0_E12145g	COG2815	serine threonine protein kinase
KLLA0_E12321g	COG1185	polyribonucleotide nucleotidyltransferase activity
KLLA0_E12475g	COG2759	Belongs to the formate--tetrahydrofolate ligase family
KLLA0_E12717g	COG2226	methyltransferase
KLLA0_E12827g	COG1785	Belongs to the alkaline phosphatase family
KLLA0_E12915g	COG3104	oligopeptide transport
KLLA0_E12981g	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
KLLA0_E13157g	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
KLLA0_E13201g	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
KLLA0_E13531g	COG0515	serine threonine protein kinase
KLLA0_E13773g	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KLLA0_E13817g	COG1028	Short-chain dehydrogenase reductase Sdr
KLLA0_E13905g	COG2224	Isocitrate lyase
KLLA0_E14059g	COG0659	secondary active sulfate transmembrane transporter activity
KLLA0_E14103g	COG0006	proline dipeptidase activity
KLLA0_E14345g	COG0101	tRNA pseudouridine synthase activity
KLLA0_E14367g	COG0513	Belongs to the DEAD box helicase family
KLLA0_E14587g	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
KLLA0_E14785g	COG2815	serine threonine protein kinase
KLLA0_E14785g	COG0515	serine threonine protein kinase
KLLA0_E14807g	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
KLLA0_E15247g	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
KLLA0_E15335g	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
KLLA0_E15357g	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
KLLA0_E16017g	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
KLLA0_E16039g	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
KLLA0_E16237g	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
KLLA0_E16281g	COG0833	amino acid
KLLA0_E16347g	COG0492	ferredoxin-NADP+ reductase activity
KLLA0_E16347g	COG3118	belongs to the thioredoxin family
KLLA0_E16391g	COG2086	electron transfer activity
KLLA0_E16435g	COG0235	Class ii aldolase
KLLA0_E16545g	COG2759	Belongs to the formate--tetrahydrofolate ligase family
KLLA0_E16567g	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
KLLA0_E16897g	COG0542	response to heat
KLLA0_E17073g	COG0515	serine threonine protein kinase
KLLA0_E17073g	COG2815	serine threonine protein kinase
KLLA0_E17183g	COG0142	geranyltranstransferase activity
KLLA0_E17205g	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
KLLA0_E17491g	COG1012	belongs to the aldehyde dehydrogenase family
KLLA0_E17645g	COG0135	phosphoribosylanthranilate isomerase activity
KLLA0_E17667g	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
KLLA0_E18349g	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
KLLA0_E18635g	COG0281	malic enzyme
KLLA0_E18679g	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
KLLA0_E19097g	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
KLLA0_E19471g	COG3239	Fatty acid desaturase
KLLA0_E19625g	COG0070	glutamate synthase
KLLA0_E19625g	COG0067	glutamate synthase
KLLA0_E19625g	COG0069	glutamate synthase activity
KLLA0_E19691g	COG0277	FAD linked oxidase domain protein
KLLA0_E19779g	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
KLLA0_E19801g	COG0442	prolyl-tRNA aminoacylation
KLLA0_E19889g	COG1064	alcohol dehydrogenase
KLLA0_E19955g	COG0084	hydrolase, TatD family'
KLLA0_E20065g	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
KLLA0_E20241g	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
KLLA0_E20285g	COG0450	alkyl hydroperoxide reductase
KLLA0_E20373g	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
KLLA0_E20527g	COG0443	Heat shock 70 kDa protein
KLLA0_E20549g	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
KLLA0_E20659g	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
KLLA0_E20945g	COG2814	Major facilitator Superfamily
KLLA0_E21077g	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
KLLA0_E21253g	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KLLA0_E21297g	COG1362	aminopeptidase activity
KLLA0_E21319g	COG0626	cystathionine gamma-synthase activity
KLLA0_E21363g	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
KLLA0_E21605g	COG0492	ferredoxin-NADP+ reductase activity
KLLA0_E21627g	COG0656	L-ascorbic acid biosynthetic process
KLLA0_E21825g	COG0180	Tryptophanyl-tRNA synthetase
KLLA0_E21891g	COG1252	NADH dehydrogenase
KLLA0_E22089g	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
KLLA0_E22111g	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
KLLA0_E22265g	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
KLLA0_E22309g	COG0443	Heat shock 70 kDa protein
KLLA0_E22375g	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
KLLA0_E22397g	COG1028	Short-chain dehydrogenase reductase Sdr
KLLA0_E22617g	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
KLLA0_E22903g	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
KLLA0_E22925g	COG5277	cytoskeleton organization
KLLA0_E23057g	COG1012	belongs to the aldehyde dehydrogenase family
KLLA0_E23167g	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
KLLA0_E23299g	COG0142	geranyltranstransferase activity
KLLA0_E23695g	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
KLLA0_E23717g	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
KLLA0_E23761g	COG2119	membrane
KLLA0_E24003g	COG1028	Short-chain dehydrogenase reductase Sdr
KLLA0_E24069g	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KLLA0_E24135g	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
KLLA0_E24267g	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
KLLA0_E24465g	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
KLLA0_E24597g	COG0443	Heat shock 70 kDa protein
KLLA0_E24795g	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
KLLA0_F00242g	COG0798	PFAM Bile acid sodium symporter
KLLA0_F00440g	COG1012	belongs to the aldehyde dehydrogenase family
KLLA0_F00506g	COG1063	alcohol dehydrogenase
KLLA0_F00528g	COG1063	alcohol dehydrogenase
KLLA0_F00704g	COG0010	Belongs to the arginase family
KLLA0_F00792g	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KLLA0_F00836g	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
KLLA0_F00858g	COG0123	including yeast histone deacetylase and acetoin utilization protein
KLLA0_F00924g	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
KLLA0_F00946g	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KLLA0_F01012g	COG0833	amino acid
KLLA0_F01034g	COG0513	Belongs to the DEAD box helicase family
KLLA0_F01144g	COG1160	GTP binding
KLLA0_F01188g	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KLLA0_F01188g	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
KLLA0_F01210g	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
KLLA0_F01507g	COG0515	serine threonine protein kinase
KLLA0_F01617g	COG0436	Aminotransferase
KLLA0_F01793g	COG0203	ribosomal protein L17
KLLA0_F01903g	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KLLA0_F02431g	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
KLLA0_F02706g	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
KLLA0_F02728g	COG0656	L-ascorbic acid biosynthetic process
KLLA0_F02838g	COG2815	serine threonine protein kinase
KLLA0_F02838g	COG0515	serine threonine protein kinase
KLLA0_F03190g	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
KLLA0_F03311g	COG2814	Major facilitator Superfamily
KLLA0_F03355g	COG2890	protein-(glutamine-N5) methyltransferase activity
KLLA0_F03509g	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
KLLA0_F04037g	COG0288	reversible hydration of carbon dioxide
KLLA0_F04103g	COG0473	3-isopropylmalate dehydrogenase activity
KLLA0_F04169g	COG0306	phosphate transporter
KLLA0_F04301g	COG3386	PFAM SMP-30 Gluconolaconase
KLLA0_F04323g	COG0655	NAD(P)H dehydrogenase (quinone) activity
KLLA0_F04477g	COG0567	Dehydrogenase, E1 component
KLLA0_F04499g	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
KLLA0_F04521g	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
KLLA0_F04741g	COG0508	dehydrogenase complex catalyzes the overall conversion of
KLLA0_F04774g	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
KLLA0_F04796g	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
KLLA0_F05005g	COG0459	protein refolding
KLLA0_F05027g	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
KLLA0_F05071g	COG0085	RNA polymerase activity
KLLA0_F05071g	COG0085	RNA polymerase activity
KLLA0_F05071g	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KLLA0_F05071g	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KLLA0_F05093g	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
KLLA0_F05181g	COG2814	Major facilitator Superfamily
KLLA0_F05401g	COG1155	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit
KLLA0_F05489g	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
KLLA0_F05632g	COG0387	Pfam Sodium calcium exchanger
KLLA0_F05676g	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KLLA0_F05753g	COG0277	FAD linked oxidase domain protein
KLLA0_F05775g	COG0656	L-ascorbic acid biosynthetic process
KLLA0_F05918g	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
KLLA0_F06072g	COG4770	biotin carboxylase activity
KLLA0_F06094g	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KLLA0_F06182g	COG0572	uridine kinase
KLLA0_F06204g	COG1643	Atp-dependent helicase
KLLA0_F06248g	COG0205	6-phosphofructokinase activity
KLLA0_F06556g	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
KLLA0_F06578g	COG0107	imidazoleglycerol-phosphate synthase activity
KLLA0_F06666g	COG1160	GTP binding
KLLA0_F06710g	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
KLLA0_F06732g	COG0386	Belongs to the glutathione peroxidase family
KLLA0_F06853g	COG2814	Major facilitator Superfamily
KLLA0_F06963g	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
KLLA0_F07007g	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
KLLA0_F07447g	COG2217	Heavy metal translocating P-type atpase
KLLA0_F07513g	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
KLLA0_F07623g	COG0515	serine threonine protein kinase
KLLA0_F07623g	COG2815	serine threonine protein kinase
KLLA0_F07843g	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
KLLA0_F07909g	COG0626	cystathionine gamma-synthase activity
KLLA0_F07975g	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
KLLA0_F07997g	COG1196	nuclear chromosome segregation
KLLA0_F08228g	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
KLLA0_F08393g	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
KLLA0_F08415g	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
KLLA0_F08437g	COG1085	galactose-1-phosphate uridylyltransferase
KLLA0_F08833g	COG1129	ABC transporter
KLLA0_F08921g	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
KLLA0_F08954g	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
KLLA0_F08998g	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
KLLA0_F09119g	COG0123	including yeast histone deacetylase and acetoin utilization protein
KLLA0_F09141g	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
KLLA0_F09163g	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KLLA0_F09185g	COG1233	COG1233 Phytoene dehydrogenase and related
KLLA0_F09273g	COG0113	porphobilinogen synthase activity
KLLA0_F09449g	COG0459	protein refolding
KLLA0_F09603g	COG0022	dehydrogenase e1 component
KLLA0_F09603g	COG0508	dehydrogenase complex catalyzes the overall conversion of
KLLA0_F09647g	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
KLLA0_F09691g	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
KLLA0_F09812g	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
KLLA0_F09955g	COG1183	phosphatidylcholine synthase activity
KLLA0_F10021g	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KLLA0_F10307g	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
KLLA0_F10351g	COG3118	belongs to the thioredoxin family
KLLA0_F10395g	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KLLA0_F10395g	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KLLA0_F10505g	COG0513	Belongs to the DEAD box helicase family
KLLA0_F10879g	COG0183	Belongs to the thiolase family
KLLA0_F11022g	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
KLLA0_F11033g	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
KLLA0_F11253g	COG0585	pseudouridine synthase activity
KLLA0_F11297g	COG0285	dihydrofolate synthase activity
KLLA0_F11319g	COG2815	serine threonine protein kinase
KLLA0_F11319g	COG0515	serine threonine protein kinase
KLLA0_F11484g	COG2274	protein secretion by the type I secretion system
KLLA0_F11770g	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
KLLA0_F11957g	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
KLLA0_F12001g	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
KLLA0_F12056g	COG0435	Glutathione S-transferase
KLLA0_F12210g	COG0488	(ABC) transporter
KLLA0_F12276g	COG0391	Required for morphogenesis under gluconeogenic growth conditions
KLLA0_F12342g	COG0538	isocitrate dehydrogenase activity
KLLA0_F12364g	COG0440	acetolactate synthase activity
KLLA0_F12386g	COG0211	Belongs to the bacterial ribosomal protein bL27 family
KLLA0_F12496g	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
KLLA0_F12562g	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
KLLA0_F12562g	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
KLLA0_F12628g	COG1012	belongs to the aldehyde dehydrogenase family
KLLA0_F12782g	COG0655	NAD(P)H dehydrogenase (quinone) activity
KLLA0_F13552g	COG0515	serine threonine protein kinase
KLLA0_F13552g	COG2815	serine threonine protein kinase
KLLA0_F13574g	COG1362	aminopeptidase activity
KLLA0_F13596g	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
KLLA0_F13640g	COG1448	Aminotransferase
KLLA0_F13684g	COG2814	Major facilitator Superfamily
KLLA0_F13706g	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KLLA0_F13926g	COG0513	Belongs to the DEAD box helicase family
KLLA0_F13970g	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
KLLA0_F13992g	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
KLLA0_F14190g	COG0515	serine threonine protein kinase
KLLA0_F14190g	COG2815	serine threonine protein kinase
KLLA0_F14366g	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
KLLA0_F14663g	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
KLLA0_F14707g	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KLLA0_F14773g	COG0355	proton-transporting ATP synthase activity, rotational mechanism
KLLA0_F14927g	COG0688	phosphatidylethanolamine metabolic process
KLLA0_F15037g	COG0492	ferredoxin-NADP+ reductase activity
KLLA0_F15103g	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KLLA0_F15389g	COG0180	Tryptophanyl-tRNA synthetase
KLLA0_F15752g	COG0513	Belongs to the DEAD box helicase family
KLLA0_F15950g	COG0513	Belongs to the DEAD box helicase family
KLLA0_F16016g	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KLLA0_F16170g	COG1648	precorrin-2 dehydrogenase activity
KLLA0_F16170g	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
KLLA0_F16258g	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
KLLA0_F16511g	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
KLLA0_F16555g	COG2857	Cytochrome c1
KLLA0_F16555g	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
KLLA0_F16665g	COG1234	tRNA 3'-trailer cleavage
KLLA0_F16753g	COG1053	succinate dehydrogenase
KLLA0_F16885g	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
KLLA0_F16929g	COG3474	cytochrome
KLLA0_F16962g	COG3961	Belongs to the TPP enzyme family
KLLA0_F17050g	COG0039	L-malate dehydrogenase activity
KLLA0_F17347g	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
KLLA0_F17435g	COG1643	Atp-dependent helicase
KLLA0_F17479g	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
KLLA0_F17655g	COG0138	bifunctional purine biosynthesis protein purh
KLLA0_F17776g	COG2814	Major facilitator Superfamily
KLLA0_F18150g	COG0316	Belongs to the HesB IscA family
KLLA0_F18194g	COG0542	response to heat
KLLA0_F18392g	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
KLLA0_F18414g	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
KLLA0_F18436g	COG0051	transcription antitermination factor activity, RNA binding
KLLA0_F18546g	COG0408	coproporphyrinogen oxidase activity
KLLA0_F18612g	COG2815	serine threonine protein kinase
KLLA0_F18612g	COG0515	serine threonine protein kinase
KLLA0_F18678g	COG1024	Enoyl-CoA hydratase
KLLA0_F18744g	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
KLLA0_F18832g	COG0149	triose-phosphate isomerase activity
KLLA0_F19041g	COG1069	ribulokinase activity
KLLA0_F19085g	COG1196	nuclear chromosome segregation
KLLA0_F19184g	COG0484	heat shock protein binding
KLLA0_F19250g	COG0230	Belongs to the bacterial ribosomal protein bL34 family
KLLA0_F19360g	COG0667	Aldo Keto reductase
KLLA0_F19536g	COG0515	serine threonine protein kinase
KLLA0_F19536g	COG2815	serine threonine protein kinase
KLLA0_F19888g	COG0714	Associated with various cellular activities
KLLA0_F20053g	COG2815	serine threonine protein kinase
KLLA0_F20053g	COG0515	serine threonine protein kinase
KLLA0_F20075g	COG1132	(ABC) transporter
KLLA0_F20141g	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
KLLA0_F20548g	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
KLLA0_F20658g	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
KLLA0_F20724g	COG1754	DNA topoisomerase type I activity
KLLA0_F20724g	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KLLA0_F20746g	COG1230	cation diffusion facilitator family transporter
KLLA0_F20768g	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
KLLA0_F20768g	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
KLLA0_F21032g	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
KLLA0_F21120g	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KLLA0_F21120g	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KLLA0_F21340g	COG0459	protein refolding
KLLA0_F21560g	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
KLLA0_F21582g	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
KLLA0_F21626g	COG0218	Necessary for normal cell division and for the maintenance of normal septation
KLLA0_F21692g	COG1716	ATPase activity
KLLA0_F21692g	COG1131	(ABC) transporter
KLLA0_F21692g	COG0842	Transport permease protein
KLLA0_F21758g	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
KLLA0_F21802g	COG0534	Mate efflux family protein
KLLA0_F22242g	COG1335	isochorismatase
KLLA0_F22946g	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
KLLA0_F23012g	COG0405	Gamma-glutamyltransferase
KLLA0_F23221g	COG0387	Pfam Sodium calcium exchanger
KLLA0_F23243g	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KLLA0_F23265g	COG3266	domain, Protein
KLLA0_F23265g	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
KLLA0_F23287g	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
KLLA0_F23375g	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KLLA0_F23397g	COG0469	pyruvate kinase activity
KLLA0_F23419g	COG0833	amino acid
KLLA0_F23914g	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
KLLA0_F24068g	COG0291	Belongs to the bacterial ribosomal protein bL35 family
KLLA0_F24156g	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
KLLA0_F24310g	COG0572	uridine kinase
KLLA0_F24398g	COG1444	tRNA N-acetyltransferase activity
KLLA0_F24640g	COG0575	Belongs to the CDS family
KLLA0_F24684g	COG0513	Belongs to the DEAD box helicase family
KLLA0_F24706g	COG0482	sulfurtransferase activity
KLLA0_F24728g	COG0483	inositol monophosphate 1-phosphatase activity
KLLA0_F24794g	COG0564	pseudouridine synthase activity
KLLA0_F24816g	COG0571	ribonuclease III activity
KLLA0_F24882g	COG0505	Belongs to the CarA family
KLLA0_F25234g	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
KLLA0_F25454g	COG2154	pterin-4-alpha-carbinolamine dehydratase
KLLA0_F25564g	COG0012	GTP binding
KLLA0_F25718g	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
KLLA0_F25784g	COG2116	formate transmembrane transporter activity
KLLA0_F25960g	COG0039	L-malate dehydrogenase activity
KLLA0_F26158g	COG2175	clavaminate synthase activity
KLLA0_F26224g	COG1643	Atp-dependent helicase
KLLA0_F26246g	COG2814	Major facilitator Superfamily
KLLA0_F26268g	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
KLLA0_F26400g	COG2132	Multicopper oxidase
KLLA0_F26455g	COG0443	Heat shock 70 kDa protein
KLLA0_F26587g	COG1956	GAF domain-containing protein
KLLA0_F26851g	COG0667	Aldo Keto reductase
KLLA0_F27093g	COG0833	amino acid
KLLA0_F27247g	COG0228	four-way junction DNA binding
KLLA0_F27489g	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
KllafMp01	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation