locus-tag	class	description
GCU50_RS00055	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
GCU50_RS00060	COG0765	amino acid transport
GCU50_RS00100	COG1192	Involved in chromosome partitioning
GCU50_RS00320	COG4974	Belongs to the 'phage' integrase family
GCU50_RS00330	COG2771	luxR family
GCU50_RS00330	COG2200	EAL domain
GCU50_RS00430	COG0438	transferase activity, transferring glycosyl groups
GCU50_RS00430	COG1216	Glycosyl transferase, family 2
GCU50_RS00435	COG0438	transferase activity, transferring glycosyl groups
GCU50_RS00435	COG1216	Glycosyl transferase, family 2
GCU50_RS00445	COG1181	Belongs to the D-alanine--D-alanine ligase family
GCU50_RS00465	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GCU50_RS00475	COG0765	amino acid transport
GCU50_RS00480	COG1126	abc transporter atp-binding protein
GCU50_RS00485	COG2197	response regulator
GCU50_RS00495	COG2197	response regulator
GCU50_RS00530	COG0814	amino acid
GCU50_RS00540	COG1528	Iron-storage protein
GCU50_RS00555	COG0477	Major facilitator Superfamily
GCU50_RS00575	COG1879	ABC-type sugar transport system periplasmic component
GCU50_RS00585	COG1172	Belongs to the binding-protein-dependent transport system permease family
GCU50_RS00595	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
GCU50_RS00600	COG0589	response to stress
GCU50_RS00640	COG0840	transmembrane signaling receptor activity
GCU50_RS00655	COG0745	RESPONSE REGULATOR receiver
GCU50_RS00690	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
GCU50_RS00705	COG3102	Protein conserved in bacteria
GCU50_RS00710	COG3142	Participates in the control of copper homeostasis
GCU50_RS00725	COG3788	relative of glutathione S-transferase, MAPEG superfamily
GCU50_RS00730	COG1801	Protein of unknown function DUF72
GCU50_RS00735	COG1335	isochorismatase
GCU50_RS00745	COG0494	nUDIX hydrolase
GCU50_RS00780	COG1108	ABC-type Mn2 Zn2 transport systems permease components
GCU50_RS00790	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
GCU50_RS00795	COG0739	heme binding
GCU50_RS00800	COG1560	Kdo2-lipid A biosynthetic process
GCU50_RS00805	COG0469	pyruvate kinase activity
GCU50_RS00810	COG1737	Transcriptional regulator
GCU50_RS00815	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
GCU50_RS00820	COG0129	dihydroxy-acid dehydratase activity
GCU50_RS00825	COG0800	Aldolase
GCU50_RS00835	COG3141	response to X-ray
GCU50_RS00850	COG1770	oligopeptidase
GCU50_RS00855	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
GCU50_RS00865	COG2372	response to copper ion
GCU50_RS00870	COG1276	copper resistance
GCU50_RS00910	COG0583	DNA-binding transcription factor activity
GCU50_RS00915	COG3321	synthase
GCU50_RS00915	COG0604	alcohol dehydrogenase
GCU50_RS00915	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GCU50_RS00915	COG4221	oxidoreductase activity
GCU50_RS00920	COG2990	Protein conserved in bacteria
GCU50_RS00945	COG3008	intermembrane lipid transfer
GCU50_RS00950	COG2995	paraquat-inducible protein a
GCU50_RS00955	COG1956	GAF domain-containing protein
GCU50_RS00975	COG2814	Major facilitator Superfamily
GCU50_RS00980	COG1414	Transcriptional regulator
GCU50_RS01015	COG2226	methyltransferase
GCU50_RS01025	COG4811	Protein of unknown function (DUF986)
GCU50_RS01030	COG3716	PTS system mannose fructose sorbose family IID component
GCU50_RS01035	COG3715	PTS system
GCU50_RS01040	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GCU50_RS01040	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
GCU50_RS01045	COG1253	flavin adenine dinucleotide binding
GCU50_RS01050	COG2200	EAL domain
GCU50_RS01055	COG1760	l-serine dehydratase
GCU50_RS01065	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
GCU50_RS01075	COG0251	oxidation-reduction process
GCU50_RS01080	COG1199	ATP-dependent helicase activity
GCU50_RS01085	COG1214	PFAM Peptidase M22, glycoprotease
GCU50_RS01090	COG3065	identical protein binding
GCU50_RS01100	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
GCU50_RS01110	COG2894	cell division
GCU50_RS01115	COG0850	regulation of cytokinetic process
GCU50_RS01125	COG0179	Fumarylacetoacetate (FAA) hydrolase
GCU50_RS01145	COG2719	SpoVR family
GCU50_RS01155	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
GCU50_RS01165	COG1619	proteins homologs of microcin C7 resistance protein MccF
GCU50_RS01170	COG0741	lytic transglycosylase activity
GCU50_RS01305	COG0515	serine threonine protein kinase
GCU50_RS01370	COG3209	COG3209 Rhs family protein
GCU50_RS01420	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
GCU50_RS01420	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
GCU50_RS01440	COG4565	transcriptional regulatory protein
GCU50_RS01445	COG3290	protein histidine kinase activity
GCU50_RS01450	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
GCU50_RS01460	COG0518	GMP synthase (glutamine-hydrolyzing) activity
GCU50_RS01460	COG0519	Catalyzes the synthesis of GMP from XMP
GCU50_RS01505	COG3284	Transcriptional regulator
GCU50_RS01530	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
GCU50_RS01535	COG4977	sequence-specific DNA binding
GCU50_RS01630	COG1846	Transcriptional regulator
GCU50_RS01635	COG1566	PFAM secretion protein HlyD family protein
GCU50_RS01640	COG2814	Major facilitator Superfamily
GCU50_RS01660	COG0840	transmembrane signaling receptor activity
GCU50_RS01665	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
GCU50_RS01675	COG1028	Short-chain dehydrogenase reductase Sdr
GCU50_RS01680	COG1063	alcohol dehydrogenase
GCU50_RS01685	COG1546	Belongs to the CinA family
GCU50_RS01690	COG3383	formate dehydrogenase (NAD+) activity
GCU50_RS01700	COG1271	oxidase subunit
GCU50_RS01705	COG1294	oxidase, subunit
GCU50_RS01715	COG1294	oxidase, subunit
GCU50_RS01720	COG1271	oxidase subunit
GCU50_RS01725	COG3546	catalase activity
GCU50_RS01730	COG3685	Protein conserved in bacteria
GCU50_RS01735	COG3685	Protein conserved in bacteria
GCU50_RS01740	COG3729	General stress protein
GCU50_RS01750	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
GCU50_RS01765	COG2323	membrane
GCU50_RS01830	COG2200	EAL domain
GCU50_RS01840	COG3038	cytochrome b561
GCU50_RS01850	COG0564	pseudouridine synthase activity
GCU50_RS01855	COG3122	Protein conserved in bacteria
GCU50_RS01860	COG1304	FMN binding
GCU50_RS01865	COG2072	flavoprotein involved in K transport
GCU50_RS01870	COG1177	transmembrane transport
GCU50_RS01875	COG1176	ABC-type spermidine putrescine transport system, permease component I
GCU50_RS01880	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
GCU50_RS01890	COG0583	DNA-binding transcription factor activity
GCU50_RS01895	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GCU50_RS01900	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
GCU50_RS01910	COG1028	Short-chain dehydrogenase reductase Sdr
GCU50_RS01910	COG0604	alcohol dehydrogenase
GCU50_RS01910	COG3321	synthase
GCU50_RS01915	COG3842	ATPase activity
GCU50_RS01935	COG1605	Chorismate mutase
GCU50_RS01945	COG5434	Belongs to the glycosyl hydrolase 28 family
GCU50_RS01950	COG2207	Transcriptional regulator
GCU50_RS01950	COG3708	Transcriptional regulator
GCU50_RS01955	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GCU50_RS01985	COG2272	Belongs to the type-B carboxylesterase lipase family
GCU50_RS02005	COG0386	Belongs to the glutathione peroxidase family
GCU50_RS02010	COG3038	cytochrome b561
GCU50_RS02030	COG2353	YceI-like domain
GCU50_RS02060	COG1028	Short-chain dehydrogenase reductase Sdr
GCU50_RS02065	COG1250	3-hydroxyacyl-CoA dehydrogenase
GCU50_RS02070	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
GCU50_RS02075	COG0183	Belongs to the thiolase family
GCU50_RS02080	COG3246	L-lysine catabolic process to acetate
GCU50_RS02085	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
GCU50_RS02090	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
GCU50_RS02130	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
GCU50_RS02135	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
GCU50_RS02140	COG1028	Short-chain dehydrogenase reductase Sdr
GCU50_RS02150	COG0154	amidase activity
GCU50_RS02180	COG1028	Short-chain dehydrogenase reductase Sdr
GCU50_RS02205	COG0179	Fumarylacetoacetate (FAA) hydrolase
GCU50_RS02210	COG2207	Transcriptional regulator
GCU50_RS02215	COG1881	PFAM PEBP family protein
GCU50_RS02225	COG0012	GTP binding
GCU50_RS02245	COG0659	secondary active sulfate transmembrane transporter activity
GCU50_RS02275	COG2890	protein-(glutamine-N5) methyltransferase activity
GCU50_RS02295	COG0387	Pfam Sodium calcium exchanger
GCU50_RS02300	COG4572	Cation transport regulator
GCU50_RS02305	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
GCU50_RS02315	COG0840	transmembrane signaling receptor activity
GCU50_RS02320	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
GCU50_RS02330	COG4932	domain protein
GCU50_RS02335	COG2197	response regulator
GCU50_RS02340	COG3850	Histidine kinase
GCU50_RS02350	COG2223	nitrite transmembrane transporter activity
GCU50_RS02355	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
GCU50_RS02360	COG1140	nitrate reductase beta subunit
GCU50_RS02365	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
GCU50_RS02370	COG2181	nitrate reductase activity
GCU50_RS02375	COG0697	spore germination
GCU50_RS02380	COG1522	sequence-specific DNA binding
GCU50_RS02405	COG0788	formyltetrahydrofolate deformylase activity
GCU50_RS02415	COG1752	Esterase of the alpha-beta hydrolase superfamily
GCU50_RS02420	COG0745	RESPONSE REGULATOR receiver
GCU50_RS02425	COG1210	Utp--glucose-1-phosphate uridylyltransferase
GCU50_RS02445	COG1454	alcohol dehydrogenase
GCU50_RS02445	COG1012	belongs to the aldehyde dehydrogenase family
GCU50_RS02450	COG2095	MarC family integral membrane protein
GCU50_RS02465	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GCU50_RS02470	COG0444	Belongs to the ABC transporter superfamily
GCU50_RS02500	COG2350	Protein conserved in bacteria
GCU50_RS02525	COG0727	PFAM Uncharacterised protein family (UPF0153)
GCU50_RS02530	COG3047	cAMP biosynthetic process
GCU50_RS02555	COG0512	Glutamine amidotransferase of anthranilate synthase
GCU50_RS02555	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
GCU50_RS02560	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
GCU50_RS02570	COG0009	L-threonylcarbamoyladenylate synthase
GCU50_RS02580	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
GCU50_RS02585	COG1028	Short-chain dehydrogenase reductase Sdr
GCU50_RS02590	COG0616	signal peptide processing
GCU50_RS02625	COG0671	phosphoesterase, PA-phosphatase related
GCU50_RS02630	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
GCU50_RS02635	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
GCU50_RS02645	COG0023	Translation Initiation Factor
GCU50_RS02655	COG1349	DNA-binding transcription factor activity
GCU50_RS02670	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
GCU50_RS02670	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
GCU50_RS02675	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
GCU50_RS02685	COG4172	Belongs to the ABC transporter superfamily
GCU50_RS02690	COG4171	peptide transport system, permease
GCU50_RS02705	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
GCU50_RS02710	COG1842	Phage shock protein A
GCU50_RS02720	COG1983	PspC domain protein
GCU50_RS02730	COG3106	COG3106 Predicted ATPase
GCU50_RS02735	COG3768	UPF0283 membrane protein
GCU50_RS02745	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
GCU50_RS02750	COG4948	Mandelate Racemase Muconate Lactonizing
GCU50_RS02755	COG2866	Carboxypeptidase
GCU50_RS02760	COG4166	transmembrane transport
GCU50_RS02770	COG3706	GGDEF domain
GCU50_RS02780	COG0840	transmembrane signaling receptor activity
GCU50_RS02790	COG0513	Belongs to the DEAD box helicase family
GCU50_RS02805	COG2329	Antibiotic biosynthesis monooxygenase
GCU50_RS02815	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GCU50_RS02815	COG0674	pyruvate-flavodoxin oxidoreductase activity
GCU50_RS02815	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
GCU50_RS02815	COG1013	pyruvate-flavodoxin oxidoreductase activity
GCU50_RS02820	COG1278	Cold shock
GCU50_RS02830	COG3042	response to heat
GCU50_RS02835	COG3187	Heat shock protein
GCU50_RS02840	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GCU50_RS02850	COG2911	Protein conserved in bacteria
GCU50_RS02860	COG3784	Protein of unknown function (DUF1318)
GCU50_RS02880	COG1643	Atp-dependent helicase
GCU50_RS02885	COG4122	O-methyltransferase activity
GCU50_RS02890	COG1538	Outer membrane efflux protein
GCU50_RS02910	COG1434	Gram-negative-bacterium-type cell wall biogenesis
GCU50_RS02915	COG2755	lipolytic protein G-D-S-L family
GCU50_RS02915	COG0657	acetylesterase activity
GCU50_RS02920	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
GCU50_RS02925	COG3038	cytochrome b561
GCU50_RS02930	COG0477	Major facilitator Superfamily
GCU50_RS02955	COG0840	transmembrane signaling receptor activity
GCU50_RS02975	COG3416	Protein conserved in bacteria
GCU50_RS02980	COG0243	molybdopterin cofactor binding
GCU50_RS02985	COG0583	DNA-binding transcription factor activity
GCU50_RS02990	COG5383	Protein conserved in bacteria
GCU50_RS03005	COG0436	Aminotransferase
GCU50_RS03015	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
GCU50_RS03020	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GCU50_RS03030	COG1595	DNA-templated transcription, initiation
GCU50_RS03040	COG0753	catalase activity
GCU50_RS03045	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
GCU50_RS03050	COG0500	methyltransferase
GCU50_RS03055	COG2195	Cleaves the N-terminal amino acid of tripeptides
GCU50_RS03060	COG0747	negative chemotaxis
GCU50_RS03070	COG0697	spore germination
GCU50_RS03080	COG3135	benzoate transporter
GCU50_RS03085	COG1396	sequence-specific DNA binding
GCU50_RS03090	COG0826	peptidase U32
GCU50_RS03100	COG0583	DNA-binding transcription factor activity
GCU50_RS03105	COG0778	Nitroreductase
GCU50_RS03110	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
GCU50_RS03135	COG0583	DNA-binding transcription factor activity
GCU50_RS03155	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
GCU50_RS03165	COG0154	amidase activity
GCU50_RS03185	COG1733	regulation of RNA biosynthetic process
GCU50_RS03190	COG1064	alcohol dehydrogenase
GCU50_RS03195	COG2610	gluconate transmembrane transporter activity
GCU50_RS03200	COG0129	dihydroxy-acid dehydratase activity
GCU50_RS03205	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GCU50_RS03210	COG1414	Transcriptional regulator
GCU50_RS03265	COG0583	DNA-binding transcription factor activity
GCU50_RS03270	COG2828	Protein conserved in bacteria
GCU50_RS03275	COG2814	Major facilitator Superfamily
GCU50_RS03280	COG0179	Fumarylacetoacetate (FAA) hydrolase
GCU50_RS03285	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
GCU50_RS03290	COG3052	prosthetic group binding
GCU50_RS03310	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
GCU50_RS03335	COG0583	DNA-binding transcription factor activity
GCU50_RS03345	COG1294	oxidase, subunit
GCU50_RS03350	COG1271	oxidase subunit
GCU50_RS03365	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GCU50_RS03370	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
GCU50_RS03375	COG3842	ATPase activity
GCU50_RS03380	COG1176	ABC-type spermidine putrescine transport system, permease component I
GCU50_RS03385	COG1177	transmembrane transport
GCU50_RS03420	COG2267	carboxylic ester hydrolase activity
GCU50_RS03440	COG0747	negative chemotaxis
GCU50_RS03450	COG3238	Protein conserved in bacteria
GCU50_RS03455	COG1247	-acetyltransferase
GCU50_RS03465	COG2130	NADP-dependent
GCU50_RS03470	COG1802	Transcriptional regulator
GCU50_RS03480	COG4772	TonB-dependent receptor
GCU50_RS03490	COG2271	Major facilitator Superfamily
GCU50_RS03505	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
GCU50_RS03505	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
GCU50_RS03510	COG1942	4-Oxalocrotonate Tautomerase
GCU50_RS03515	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
GCU50_RS03525	COG3842	ATPase activity
GCU50_RS03530	COG1840	ABC-type Fe3 transport system, periplasmic component
GCU50_RS03535	COG1178	ABC-type Fe3 transport system permease component
GCU50_RS03540	COG2162	N-hydroxyarylamine O-acetyltransferase activity
GCU50_RS03560	COG0437	4 iron, 4 sulfur cluster binding
GCU50_RS03565	COG2864	formate dehydrogenase
GCU50_RS03570	COG2814	Major facilitator Superfamily
GCU50_RS03585	COG1064	alcohol dehydrogenase
GCU50_RS03595	COG0488	(ABC) transporter
GCU50_RS03615	COG0840	transmembrane signaling receptor activity
GCU50_RS03620	COG2200	EAL domain
GCU50_RS03630	COG0028	Belongs to the TPP enzyme family
GCU50_RS03650	COG1574	metal-dependent hydrolase with the TIM-barrel fold
GCU50_RS03675	COG4191	Histidine kinase
GCU50_RS03680	COG4566	intracellular signal transduction
GCU50_RS03700	COG2814	Major facilitator Superfamily
GCU50_RS03740	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
GCU50_RS03745	COG1733	regulation of RNA biosynthetic process
GCU50_RS03775	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
GCU50_RS03780	COG0076	glutamate decarboxylase activity
GCU50_RS03785	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
GCU50_RS03790	COG0527	aspartate kinase activity
GCU50_RS03795	COG4628	conserved protein (DUF2132)
GCU50_RS03800	COG1649	PFAM Uncharacterised BCR, COG1649
GCU50_RS03830	COG1275	C4-dicarboxylate transporter malic acid transport protein
GCU50_RS03845	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
GCU50_RS03850	COG2864	formate dehydrogenase
GCU50_RS03855	COG0437	4 iron, 4 sulfur cluster binding
GCU50_RS03860	COG0243	molybdopterin cofactor binding
GCU50_RS03860	COG3383	formate dehydrogenase (NAD+) activity
GCU50_RS03875	COG4221	oxidoreductase activity
GCU50_RS03890	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
GCU50_RS03910	COG0154	amidase activity
GCU50_RS04015	COG2205	protein histidine kinase activity
GCU50_RS04020	COG3604	Transcriptional regulator
GCU50_RS04035	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
GCU50_RS04040	COG0840	transmembrane signaling receptor activity
GCU50_RS04045	COG1012	belongs to the aldehyde dehydrogenase family
GCU50_RS04050	COG0583	DNA-binding transcription factor activity
GCU50_RS04055	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
GCU50_RS04065	COG3781	membrane
GCU50_RS04070	COG0246	Mannitol dehydrogenase
GCU50_RS04080	COG3706	GGDEF domain
GCU50_RS04085	COG3706	GGDEF domain
GCU50_RS04090	COG2199	diguanylate cyclase activity
GCU50_RS04105	COG0840	transmembrane signaling receptor activity
GCU50_RS04110	COG1012	belongs to the aldehyde dehydrogenase family
GCU50_RS04115	COG0583	DNA-binding transcription factor activity
GCU50_RS04120	COG4943	cyclic-guanylate-specific phosphodiesterase activity
GCU50_RS04140	COG0583	DNA-binding transcription factor activity
GCU50_RS04145	COG1028	Short-chain dehydrogenase reductase Sdr
GCU50_RS04150	COG0583	DNA-binding transcription factor activity
GCU50_RS04170	COG4993	Dehydrogenase
GCU50_RS04190	COG3708	Transcriptional regulator
GCU50_RS04190	COG2207	Transcriptional regulator
GCU50_RS04195	COG1556	Lactate utilization protein
GCU50_RS04200	COG1139	Iron-sulfur cluster binding protein
GCU50_RS04205	COG0247	lactate metabolic process
GCU50_RS04225	COG0039	L-malate dehydrogenase activity
GCU50_RS04235	COG2814	Major facilitator Superfamily
GCU50_RS04240	COG0596	Alpha beta hydrolase
GCU50_RS04265	COG0697	spore germination
GCU50_RS04270	COG2814	Major facilitator Superfamily
GCU50_RS04275	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
GCU50_RS04305	COG0339	signal peptide processing
GCU50_RS04310	COG4221	oxidoreductase activity
GCU50_RS04315	COG1802	Transcriptional regulator
GCU50_RS04330	COG0246	Mannitol dehydrogenase
GCU50_RS04335	COG0477	Major facilitator Superfamily
GCU50_RS04340	COG1063	alcohol dehydrogenase
GCU50_RS04345	COG4948	Mandelate Racemase Muconate Lactonizing
GCU50_RS04360	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GCU50_RS04380	COG0437	4 iron, 4 sulfur cluster binding
GCU50_RS04385	COG3302	dmso reductase anchor subunit
GCU50_RS04390	COG3381	protein complex oligomerization
GCU50_RS04395	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
GCU50_RS04400	COG1940	carbohydrate kinase activity
GCU50_RS04405	COG0583	DNA-binding transcription factor activity
GCU50_RS04410	COG2814	Major facilitator Superfamily
GCU50_RS04425	COG3591	Belongs to the peptidase S1B family
GCU50_RS04440	COG2076	Multidrug Resistance protein
GCU50_RS04470	COG2840	Smr protein MutS2
GCU50_RS04475	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
GCU50_RS04480	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GCU50_RS04490	COG0668	transmembrane transport
GCU50_RS04495	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
GCU50_RS04500	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
GCU50_RS04515	COG0531	amino acid
GCU50_RS04520	COG3136	membrane protein required for alginate biosynthesis
GCU50_RS04525	COG0745	RESPONSE REGULATOR receiver
GCU50_RS04530	COG2205	protein histidine kinase activity
GCU50_RS04540	COG0114	fumarate hydratase activity
GCU50_RS04545	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
GCU50_RS04545	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
GCU50_RS04555	COG5339	Protein conserved in bacteria
GCU50_RS04575	COG0673	inositol 2-dehydrogenase activity
GCU50_RS04615	COG4659	FMN binding
GCU50_RS04625	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
GCU50_RS04640	COG0625	glutathione transferase activity
GCU50_RS04645	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
GCU50_RS04660	COG3895	Periplasmic Protein
GCU50_RS04685	COG2032	superoxide dismutase activity
GCU50_RS04690	COG4989	oxidoreductase activity
GCU50_RS04695	COG3313	Fe-S protein
GCU50_RS04700	COG1309	transcriptional regulator
GCU50_RS04705	COG1902	pentaerythritol trinitrate reductase activity
GCU50_RS04710	COG0346	lactoylglutathione lyase activity
GCU50_RS04720	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
GCU50_RS04725	COG0791	NLP P60 protein
GCU50_RS04735	COG2814	Major facilitator Superfamily
GCU50_RS04750	COG0583	DNA-binding transcription factor activity
GCU50_RS04755	COG2814	Major facilitator Superfamily
GCU50_RS04760	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
GCU50_RS04765	COG0307	riboflavin synthase, alpha
GCU50_RS04770	COG0534	Mate efflux family protein
GCU50_RS04785	COG1064	alcohol dehydrogenase
GCU50_RS04790	COG1126	abc transporter atp-binding protein
GCU50_RS04795	COG0765	amino acid transport
GCU50_RS04820	COG1376	ErfK ybiS ycfS ynhG family protein
GCU50_RS04825	COG2166	iron-sulfur cluster assembly
GCU50_RS04835	COG0719	Fe-S assembly protein
GCU50_RS04840	COG0396	ATPase activity
GCU50_RS04845	COG0719	Fe-S assembly protein
GCU50_RS04850	COG0316	Belongs to the HesB IscA family
GCU50_RS04855	COG2267	carboxylic ester hydrolase activity
GCU50_RS04895	COG1560	Kdo2-lipid A biosynthetic process
GCU50_RS04900	COG2050	protein possibly involved in aromatic compounds catabolism
GCU50_RS04905	COG0247	lactate metabolic process
GCU50_RS04905	COG0277	FAD linked oxidase domain protein
GCU50_RS04910	COG0628	permease
GCU50_RS04920	COG1472	Belongs to the glycosyl hydrolase 3 family
GCU50_RS04925	COG2211	Major facilitator Superfamily
GCU50_RS04950	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
GCU50_RS04950	COG0574	Belongs to the PEP-utilizing enzyme family
GCU50_RS04960	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
GCU50_RS04975	COG0791	NLP P60 protein
GCU50_RS04985	COG0386	Belongs to the glutathione peroxidase family
GCU50_RS04990	COG4139	cobalamin transport
GCU50_RS04995	COG0776	regulation of translation
GCU50_RS05000	COG0072	phenylalanine-tRNA ligase activity
GCU50_RS05000	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GCU50_RS05035	COG0859	PFAM glycosyl transferase family 9
GCU50_RS05055	COG3137	Salt-induced outer membrane protein
GCU50_RS05060	COG1105	Belongs to the carbohydrate kinase PfkB family
GCU50_RS05070	COG3001	Fructosamine kinase
GCU50_RS05080	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GCU50_RS05085	COG1028	Short-chain dehydrogenase reductase Sdr
GCU50_RS05090	COG1988	membrane-bound metal-dependent
GCU50_RS05095	COG1823	symporter activity
GCU50_RS05110	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GCU50_RS05120	COG0322	excinuclease ABC activity
GCU50_RS05130	COG3678	ATP-independent chaperone mediated protein folding
GCU50_RS05140	COG3724	N-succinylarginine dihydrolase activity
GCU50_RS05145	COG1012	belongs to the aldehyde dehydrogenase family
GCU50_RS05165	COG2897	thiosulfate sulfurtransferase activity
GCU50_RS05170	COG0494	nUDIX hydrolase
GCU50_RS05180	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
GCU50_RS05185	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
GCU50_RS05200	COG0778	Nitroreductase
GCU50_RS05205	COG0616	signal peptide processing
GCU50_RS05210	COG0252	asparaginase activity
GCU50_RS05215	COG1335	isochorismatase
GCU50_RS05220	COG3139	Protein of unknown function (DUF1315)
GCU50_RS05240	COG0656	L-ascorbic acid biosynthetic process
GCU50_RS05245	COG3713	MltA-interacting MipA family protein
GCU50_RS05255	COG1696	Membrane protein involved in D-alanine export
GCU50_RS05260	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GCU50_RS05270	COG2766	serine protein kinase
GCU50_RS05275	COG2718	Belongs to the UPF0229 family
GCU50_RS05285	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
GCU50_RS05300	COG2207	Transcriptional regulator
GCU50_RS05305	COG2807	transmembrane transport
GCU50_RS05320	COG3189	MarR family transcriptional regulator
GCU50_RS05330	COG3042	response to heat
GCU50_RS05350	COG0840	transmembrane signaling receptor activity
GCU50_RS05405	COG1473	amidohydrolase
GCU50_RS05410	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
GCU50_RS05415	COG0251	oxidation-reduction process
GCU50_RS05435	COG5001	Diguanylate cyclase
GCU50_RS05440	COG0840	transmembrane signaling receptor activity
GCU50_RS05455	COG0840	transmembrane signaling receptor activity
GCU50_RS05470	COG1028	Short-chain dehydrogenase reductase Sdr
GCU50_RS05475	COG0604	alcohol dehydrogenase
GCU50_RS05475	COG1028	Short-chain dehydrogenase reductase Sdr
GCU50_RS05475	COG3321	synthase
GCU50_RS05495	COG0583	DNA-binding transcription factor activity
GCU50_RS05505	COG0667	Aldo Keto reductase
GCU50_RS05520	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
GCU50_RS05525	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
GCU50_RS05530	COG0538	isocitrate dehydrogenase activity
GCU50_RS05535	COG1187	pseudouridine synthase activity
GCU50_RS05550	COG2915	High frequency lysogenization protein hflD homolog
GCU50_RS05555	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
GCU50_RS05560	COG0745	RESPONSE REGULATOR receiver
GCU50_RS05570	COG2850	peptidyl-arginine hydroxylation
GCU50_RS05590	COG1012	belongs to the aldehyde dehydrogenase family
GCU50_RS05620	COG4591	ABC-type transport system involved in lipoprotein release permease component
GCU50_RS05625	COG1136	(ABC) transporter
GCU50_RS05630	COG4591	ABC-type transport system involved in lipoprotein release permease component
GCU50_RS05635	COG4763	Acyl-transferase
GCU50_RS05640	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
GCU50_RS05645	COG1376	ErfK ybiS ycfS ynhG family protein
GCU50_RS05645	COG1388	LysM domain
GCU50_RS05655	COG1309	transcriptional regulator
GCU50_RS05660	COG3134	Outer membrane lipoprotein
GCU50_RS05665	COG1252	NADH dehydrogenase
GCU50_RS05680	COG0510	thiamine kinase activity
GCU50_RS05685	COG3417	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b)
GCU50_RS05690	COG5633	Lipoprotein
GCU50_RS05695	COG0537	adenosine 5'-monophosphoramidase activity
GCU50_RS05705	COG0084	hydrolase, TatD family'
GCU50_RS05710	COG0470	DNA polymerase III
GCU50_RS05720	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
GCU50_RS05725	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
GCU50_RS05730	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GCU50_RS05740	COG1028	Short-chain dehydrogenase reductase Sdr
GCU50_RS05745	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
GCU50_RS05765	COG1399	metal-binding, possibly nucleic acid-binding protein
GCU50_RS05770	COG0424	maF-like protein
GCU50_RS05775	COG0823	Involved in the tonB-independent uptake of proteins
GCU50_RS05775	COG1506	peptidase
GCU50_RS05780	COG0564	pseudouridine synthase activity
GCU50_RS05785	COG1530	ribonuclease E activity
GCU50_RS05790	COG0583	DNA-binding transcription factor activity
GCU50_RS05795	COG2814	Major facilitator Superfamily
GCU50_RS05800	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
GCU50_RS05805	COG1256	bacterial-type flagellum assembly
GCU50_RS05825	COG4786	Flagellar basal body rod
GCU50_RS05830	COG4787	bacterial-type flagellum-dependent cell motility
GCU50_RS05835	COG1749	Flagellar hook protein flgE
GCU50_RS05840	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
GCU50_RS05870	COG0728	peptidoglycan biosynthetic process
GCU50_RS05875	COG0673	inositol 2-dehydrogenase activity
GCU50_RS05880	COG3132	Protein of unknown function, DUF480
GCU50_RS05885	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GCU50_RS05940	COG1560	Kdo2-lipid A biosynthetic process
GCU50_RS05955	COG5645	(Lipo)protein
GCU50_RS05975	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
GCU50_RS05990	COG3381	protein complex oligomerization
GCU50_RS06015	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
GCU50_RS06020	COG1702	phosphate starvation-inducible protein PhoH
GCU50_RS06040	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
GCU50_RS06065	COG1069	ribulokinase activity
GCU50_RS06070	COG1172	Belongs to the binding-protein-dependent transport system permease family
GCU50_RS06075	COG1172	Belongs to the binding-protein-dependent transport system permease family
GCU50_RS06080	COG1129	ABC transporter
GCU50_RS06100	COG1309	transcriptional regulator
GCU50_RS06130	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
GCU50_RS06140	COG3729	General stress protein
GCU50_RS06160	COG4221	oxidoreductase activity
GCU50_RS06165	COG2207	Transcriptional regulator
GCU50_RS06175	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
GCU50_RS06185	COG0765	amino acid transport
GCU50_RS06240	COG1953	Uracil, thiamine, allantoin
GCU50_RS06245	COG0402	S-adenosylhomocysteine deaminase activity
GCU50_RS06250	COG2351	hydroxyisourate hydrolase activity
GCU50_RS06260	COG2233	PERMEase
GCU50_RS06265	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GCU50_RS06290	COG3328	transposase activity
GCU50_RS06320	COG3210	domain, Protein
GCU50_RS06340	COG0840	transmembrane signaling receptor activity
GCU50_RS06365	COG0670	Belongs to the BI1 family
GCU50_RS06380	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
GCU50_RS06390	COG1832	CoA-binding protein
GCU50_RS06400	COG0210	DNA helicase
GCU50_RS06405	COG3304	Inner membrane component domain
GCU50_RS06410	COG1289	transmembrane transporter activity
GCU50_RS06415	COG3070	regulator of competence-specific genes
GCU50_RS06435	COG1067	ATP-dependent peptidase activity
GCU50_RS06445	COG3130	regulation of translation
GCU50_RS06450	COG3009	Protein conserved in bacteria
GCU50_RS06455	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
GCU50_RS06455	COG3008	intermembrane lipid transfer
GCU50_RS06460	COG2995	paraquat-inducible protein a
GCU50_RS06465	COG0488	(ABC) transporter
GCU50_RS06475	COG3217	Mosc domain protein beta barrel domain protein
GCU50_RS06475	COG0633	Ferredoxin
GCU50_RS06490	COG0431	NADPH-dependent FMN reductase
GCU50_RS06495	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
GCU50_RS06505	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GCU50_RS06510	COG1116	anion transmembrane transporter activity
GCU50_RS06515	COG0308	aminopeptidase N
GCU50_RS06525	COG0017	Asparaginyl-tRNA synthetase
GCU50_RS06535	COG1448	Aminotransferase
GCU50_RS06540	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GCU50_RS06545	COG3108	Peptidase M15
GCU50_RS06550	COG2989	Protein conserved in bacteria
GCU50_RS06560	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
GCU50_RS06570	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
GCU50_RS06575	COG1434	Gram-negative-bacterium-type cell wall biogenesis
GCU50_RS06580	COG3173	Aminoglycoside phosphotransferase
GCU50_RS06590	COG2835	tetraacyldisaccharide 4'-kinase activity
GCU50_RS06595	COG3214	Protein conserved in bacteria
GCU50_RS06610	COG2333	competence protein COMEC
GCU50_RS06610	COG0658	competence protein
GCU50_RS06620	COG0539	negative regulation of cytoplasmic translation
GCU50_RS06640	COG2323	membrane
GCU50_RS06645	COG1944	ATP diphosphatase activity
GCU50_RS06650	COG2116	formate transmembrane transporter activity
GCU50_RS06655	COG1882	Formate acetyltransferase
GCU50_RS06660	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
GCU50_RS06665	COG0477	Major facilitator Superfamily
GCU50_RS06670	COG3302	dmso reductase anchor subunit
GCU50_RS06675	COG0437	4 iron, 4 sulfur cluster binding
GCU50_RS06680	COG0243	molybdopterin cofactor binding
GCU50_RS06690	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
GCU50_RS06700	COG1178	ABC-type Fe3 transport system permease component
GCU50_RS06700	COG1674	ftsk spoiiie
GCU50_RS06705	COG1522	sequence-specific DNA binding
GCU50_RS06710	COG0492	ferredoxin-NADP+ reductase activity
GCU50_RS06715	COG4988	ABC transporter
GCU50_RS06720	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
GCU50_RS06735	COG0542	response to heat
GCU50_RS06745	COG1278	Cold shock
GCU50_RS06755	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GCU50_RS06760	COG2990	Protein conserved in bacteria
GCU50_RS06765	COG3593	DNA synthesis involved in DNA repair
GCU50_RS06770	COG2431	L-lysine efflux transmembrane transporter activity
GCU50_RS06775	COG1151	hydroxylamine reductase activity
GCU50_RS06780	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
GCU50_RS06790	COG0028	Belongs to the TPP enzyme family
GCU50_RS06795	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
GCU50_RS06800	COG0702	epimerase
GCU50_RS06805	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GCU50_RS06815	COG3023	N-Acetylmuramoyl-L-alanine amidase
GCU50_RS06820	COG0393	Putative heavy-metal-binding
GCU50_RS06830	COG1126	abc transporter atp-binding protein
GCU50_RS06835	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GCU50_RS06840	COG4215	(ABC) transporter
GCU50_RS06845	COG4160	amino acid transport
GCU50_RS06850	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GCU50_RS06855	COG1414	Transcriptional regulator
GCU50_RS06860	COG3507	Belongs to the glycosyl hydrolase 43 family
GCU50_RS06865	COG2211	Major facilitator Superfamily
GCU50_RS06870	COG0129	dihydroxy-acid dehydratase activity
GCU50_RS06875	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GCU50_RS06890	COG1177	transmembrane transport
GCU50_RS06895	COG1176	ABC-type spermidine putrescine transport system, permease component I
GCU50_RS06900	COG3842	ATPase activity
GCU50_RS06905	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
GCU50_RS06985	COG3226	Transcriptional regulator
GCU50_RS06990	COG0738	Major facilitator superfamily
GCU50_RS06995	COG2814	Major facilitator Superfamily
GCU50_RS07000	COG0671	phosphoesterase, PA-phosphatase related
GCU50_RS07005	COG1349	DNA-binding transcription factor activity
GCU50_RS07010	COG1686	Belongs to the peptidase S11 family
GCU50_RS07015	COG0625	glutathione transferase activity
GCU50_RS07020	COG2133	pyrroloquinoline quinone binding
GCU50_RS07035	COG4770	biotin carboxylase activity
GCU50_RS07040	COG3665	Urea carboxylase-associated protein
GCU50_RS07045	COG3665	Urea carboxylase-associated protein
GCU50_RS07050	COG3842	ATPase activity
GCU50_RS07155	COG4172	Belongs to the ABC transporter superfamily
GCU50_RS07160	COG1446	asparaginase
GCU50_RS07165	COG0303	'Molybdopterin
GCU50_RS07170	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
GCU50_RS07175	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
GCU50_RS07180	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
GCU50_RS07185	COG1882	Formate acetyltransferase
GCU50_RS07190	COG0561	phosphatase activity
GCU50_RS07200	COG1609	Transcriptional regulator
GCU50_RS07205	COG2271	Major facilitator Superfamily
GCU50_RS07215	COG0488	(ABC) transporter
GCU50_RS07220	COG1376	ErfK ybiS ycfS ynhG family protein
GCU50_RS07225	COG2188	Transcriptional regulator
GCU50_RS07230	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GCU50_RS07235	COG2723	6-phospho-beta-galactosidase activity
GCU50_RS07240	COG0667	Aldo Keto reductase
GCU50_RS07250	COG2814	Major facilitator Superfamily
GCU50_RS07260	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
GCU50_RS07265	COG1321	iron dependent repressor
GCU50_RS07275	COG2194	sulfuric ester hydrolase activity
GCU50_RS07280	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
GCU50_RS07300	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GCU50_RS07305	COG0765	amino acid transport
GCU50_RS07310	COG1126	abc transporter atp-binding protein
GCU50_RS07315	COG0668	transmembrane transport
GCU50_RS07330	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
GCU50_RS07340	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
GCU50_RS07350	COG0513	Belongs to the DEAD box helicase family
GCU50_RS07355	COG1309	transcriptional regulator
GCU50_RS07360	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GCU50_RS07365	COG1131	(ABC) transporter
GCU50_RS07370	COG0842	Transport permease protein
GCU50_RS07375	COG0842	Transport permease protein
GCU50_RS07385	COG3568	Endonuclease Exonuclease Phosphatase
GCU50_RS07390	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GCU50_RS07395	COG0392	lysyltransferase activity
GCU50_RS07400	COG0670	Belongs to the BI1 family
GCU50_RS07410	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
GCU50_RS07420	COG0521	Mo-molybdopterin cofactor biosynthetic process
GCU50_RS07430	COG0391	Required for morphogenesis under gluconeogenic growth conditions
GCU50_RS07435	COG2194	sulfuric ester hydrolase activity
GCU50_RS07445	COG0642	Histidine kinase
GCU50_RS07450	COG0556	nucleotide-excision repair
GCU50_RS07455	COG0410	ABC transporter
GCU50_RS07480	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
GCU50_RS07485	COG1881	PFAM PEBP family protein
GCU50_RS07500	COG4677	pectinesterase activity
GCU50_RS07505	COG2706	6-phosphogluconolactonase activity
GCU50_RS07510	COG0561	phosphatase activity
GCU50_RS07520	COG4149	molybdate abc transporter
GCU50_RS07525	COG0725	ABC transporter, periplasmic molybdate-binding protein
GCU50_RS07535	COG3585	molybdate ion transport
GCU50_RS07535	COG2005	Transcriptional regulator
GCU50_RS07540	COG1119	ATPase activity
GCU50_RS07545	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
GCU50_RS07550	COG1085	galactose-1-phosphate uridylyltransferase
GCU50_RS07560	COG2017	converts alpha-aldose to the beta-anomer
GCU50_RS07570	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
GCU50_RS07585	COG3201	nicotinamide mononucleotide transporter
GCU50_RS07590	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
GCU50_RS07620	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
GCU50_RS07625	COG2885	chlorophyll binding
GCU50_RS07635	COG3064	Membrane
GCU50_RS07640	COG0848	biopolymer transport protein
GCU50_RS07645	COG0811	peptide transport
GCU50_RS07650	COG0824	Thioesterase
GCU50_RS07655	COG3790	cyd operon protein YbgE
GCU50_RS07660	COG4890	Cyd operon protein YbgT
GCU50_RS07665	COG1294	oxidase, subunit
GCU50_RS07670	COG1271	oxidase subunit
GCU50_RS07680	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
GCU50_RS07690	COG0508	dehydrogenase complex catalyzes the overall conversion of
GCU50_RS07695	COG0567	Dehydrogenase, E1 component
GCU50_RS07700	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
GCU50_RS07705	COG1053	succinate dehydrogenase
GCU50_RS07710	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
GCU50_RS07715	COG2009	succinate dehydrogenase
GCU50_RS07720	COG0372	Belongs to the citrate synthase family
GCU50_RS07735	COG1984	allophanate hydrolase subunit 2
GCU50_RS07740	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
GCU50_RS07745	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
GCU50_RS07750	COG0415	Belongs to the DNA photolyase family
GCU50_RS07765	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
GCU50_RS07770	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
GCU50_RS07780	COG2205	protein histidine kinase activity
GCU50_RS07785	COG0745	RESPONSE REGULATOR receiver
GCU50_RS07795	COG0033	Phosphoglucomutase
GCU50_RS07805	COG0596	Alpha beta hydrolase
GCU50_RS07820	COG0735	belongs to the Fur family
GCU50_RS07840	COG2190	(PTS) system
GCU50_RS07840	COG1263	PTS System
GCU50_RS07840	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GCU50_RS07850	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
GCU50_RS07855	COG1846	Transcriptional regulator
GCU50_RS07855	COG1940	carbohydrate kinase activity
GCU50_RS07860	COG0647	UMP catabolic process
GCU50_RS07865	COG0367	asparagine synthase
GCU50_RS07910	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GCU50_RS07920	COG1702	phosphate starvation-inducible protein PhoH
GCU50_RS07925	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
GCU50_RS07950	COG0765	amino acid transport
GCU50_RS07955	COG0765	amino acid transport
GCU50_RS07960	COG1126	abc transporter atp-binding protein
GCU50_RS07965	COG2888	peptidyl-tyrosine sulfation
GCU50_RS07980	COG1466	dna polymerase III delta subunit
GCU50_RS07990	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
GCU50_RS08000	COG0799	negative regulation of ribosome biogenesis
GCU50_RS08010	COG0768	penicillin binding
GCU50_RS08015	COG0772	Belongs to the SEDS family
GCU50_RS08020	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
GCU50_RS08025	COG1686	Belongs to the peptidase S11 family
GCU50_RS08030	COG2921	Belongs to the UPF0250 family
GCU50_RS08040	COG0583	DNA-binding transcription factor activity
GCU50_RS08055	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
GCU50_RS08060	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
GCU50_RS08085	COG3719	Belongs to the RNase T2 family
GCU50_RS08090	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
GCU50_RS08110	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
GCU50_RS08115	COG0436	Aminotransferase
GCU50_RS08125	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
GCU50_RS08170	COG3423	Transcriptional regulator
GCU50_RS08180	COG2026	Addiction module toxin, RelE StbE family
GCU50_RS08190	COG1309	transcriptional regulator
GCU50_RS08200	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GCU50_RS08205	COG1486	melibiose metabolic process
GCU50_RS08210	COG1447	Phosphotransferase system cellobiose-specific component IIA
GCU50_RS08345	COG0235	Class ii aldolase
GCU50_RS08350	COG3623	hexulose-6-phosphate isomerase
GCU50_RS08355	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
GCU50_RS08360	COG1070	Carbohydrate kinase
GCU50_RS08375	COG2731	YhcH YjgK YiaL family protein
GCU50_RS08385	COG1414	Transcriptional regulator
GCU50_RS08420	COG1120	ATPase activity
GCU50_RS08425	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GCU50_RS08455	COG1172	Belongs to the binding-protein-dependent transport system permease family
GCU50_RS08460	COG1129	ABC transporter
GCU50_RS08465	COG0371	Dehydrogenase
GCU50_RS08470	COG1309	transcriptional regulator
GCU50_RS08480	COG2879	small protein
GCU50_RS08485	COG1966	Carbon starvation protein
GCU50_RS08495	COG1028	Short-chain dehydrogenase reductase Sdr
GCU50_RS08500	COG3433	isochorismatase activity
GCU50_RS08500	COG1535	isochorismatase
GCU50_RS08505	COG1021	2,3-dihydroxybenzoate-AMP ligase
GCU50_RS08510	COG1169	isochorismate synthase
GCU50_RS08515	COG4592	Periplasmic binding protein
GCU50_RS08525	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GCU50_RS08530	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GCU50_RS08535	COG1120	ATPase activity
GCU50_RS08540	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GCU50_RS08540	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
GCU50_RS08545	COG3251	PFAM MbtH domain protein
GCU50_RS08550	COG2382	esterase
GCU50_RS08555	COG4771	TonB-dependent receptor
GCU50_RS08560	COG2977	Belongs to the P-Pant transferase superfamily
GCU50_RS08575	COG0601	transmembrane transport
GCU50_RS08580	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GCU50_RS08620	COG4608	Belongs to the ABC transporter superfamily
GCU50_RS08630	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
GCU50_RS08635	COG4221	oxidoreductase activity
GCU50_RS08640	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
GCU50_RS08645	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GCU50_RS08650	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GCU50_RS08655	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
GCU50_RS08665	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
GCU50_RS08665	COG0493	'glutamate synthase
GCU50_RS08685	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
GCU50_RS08700	COG2207	Transcriptional regulator
GCU50_RS08715	COG1393	Belongs to the ArsC family
GCU50_RS08725	COG0640	Transcriptional regulator
GCU50_RS08730	COG5002	protein histidine kinase activity
GCU50_RS08740	COG2207	Transcriptional regulator
GCU50_RS08745	COG0840	transmembrane signaling receptor activity
GCU50_RS08795	COG4608	Belongs to the ABC transporter superfamily
GCU50_RS08800	COG0444	Belongs to the ABC transporter superfamily
GCU50_RS08805	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GCU50_RS08810	COG0601	transmembrane transport
GCU50_RS08820	COG2267	carboxylic ester hydrolase activity
GCU50_RS08830	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
GCU50_RS08845	COG1902	pentaerythritol trinitrate reductase activity
GCU50_RS08875	COG1028	Short-chain dehydrogenase reductase Sdr
GCU50_RS08905	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
GCU50_RS08905	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
GCU50_RS08910	COG5001	Diguanylate cyclase
GCU50_RS08915	COG0840	transmembrane signaling receptor activity
GCU50_RS08925	COG5000	phosphorelay sensor kinase activity
GCU50_RS08935	COG2204	response regulator
GCU50_RS08940	COG0071	Belongs to the small heat shock protein (HSP20) family
GCU50_RS08955	COG0840	transmembrane signaling receptor activity
GCU50_RS08980	COG0745	RESPONSE REGULATOR receiver
GCU50_RS09010	COG1028	Short-chain dehydrogenase reductase Sdr
GCU50_RS09015	COG1902	pentaerythritol trinitrate reductase activity
GCU50_RS09020	COG0583	DNA-binding transcription factor activity
GCU50_RS09050	COG1733	regulation of RNA biosynthetic process
GCU50_RS09100	COG2501	S4 domain
GCU50_RS09105	COG2190	(PTS) system
GCU50_RS09105	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GCU50_RS09105	COG1263	PTS System
GCU50_RS09110	COG1609	Transcriptional regulator
GCU50_RS09120	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
GCU50_RS09125	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
GCU50_RS09130	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
GCU50_RS09135	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
GCU50_RS09155	COG1464	Belongs to the NlpA lipoprotein family
GCU50_RS09165	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
GCU50_RS09170	COG4181	ATPase activity
GCU50_RS09175	COG2755	lipolytic protein G-D-S-L family
GCU50_RS09180	COG0300	oxidoreductase activity
GCU50_RS09185	COG3118	belongs to the thioredoxin family
GCU50_RS09190	COG0330	HflC and HflK could
GCU50_RS09195	COG1585	Membrane protein implicated in regulation of membrane protease activity
GCU50_RS09210	COG3735	TraB family
GCU50_RS09215	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
GCU50_RS09225	COG2223	nitrite transmembrane transporter activity
GCU50_RS09230	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
GCU50_RS09230	COG4651	solute:proton antiporter activity
GCU50_RS09235	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GCU50_RS09240	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
GCU50_RS09265	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
GCU50_RS09285	COG3923	Primosomal replication protein n
GCU50_RS09295	COG3264	Mechanosensitive ion channel
GCU50_RS09295	COG1196	nuclear chromosome segregation
GCU50_RS09300	COG1309	transcriptional regulator
GCU50_RS09305	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GCU50_RS09310	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GCU50_RS09345	COG0257	Belongs to the bacterial ribosomal protein bL36 family
GCU50_RS09370	COG2011	ABC-type metal ion transport system permease component
GCU50_RS09380	COG5507	3-demethylubiquinone-9 3-methyltransferase
GCU50_RS09385	COG3250	beta-galactosidase activity
GCU50_RS09390	COG1609	Transcriptional regulator
GCU50_RS09415	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GCU50_RS09425	COG3695	enzyme binding
GCU50_RS09430	COG3126	Type III secretion system lipoprotein chaperone (YscW)
GCU50_RS09435	COG1946	Acyl-CoA thioesterase
GCU50_RS09440	COG0004	ammonium transporteR
GCU50_RS09445	COG0347	Belongs to the P(II) protein family
GCU50_RS09450	COG1132	(ABC) transporter
GCU50_RS09455	COG1132	(ABC) transporter
GCU50_RS09460	COG1522	sequence-specific DNA binding
GCU50_RS09470	COG0561	phosphatase activity
GCU50_RS09475	COG4533	DNA binding
GCU50_RS09485	COG0824	Thioesterase
GCU50_RS09490	COG1555	photosystem II stabilization
GCU50_RS09495	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GCU50_RS09500	COG0776	regulation of translation
GCU50_RS09505	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
GCU50_RS09525	COG0271	Belongs to the BolA IbaG family
GCU50_RS09530	COG3056	Lipoprotein
GCU50_RS09535	COG2223	nitrite transmembrane transporter activity
GCU50_RS09540	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
GCU50_RS09545	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
GCU50_RS09550	COG1845	cytochrome c oxidase, subunit III
GCU50_RS09555	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
GCU50_RS09560	COG0109	protoheme IX farnesyltransferase activity
GCU50_RS09565	COG2814	Major facilitator Superfamily
GCU50_RS09570	COG1666	GTP binding
GCU50_RS09575	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
GCU50_RS09595	COG0142	geranyltranstransferase activity
GCU50_RS09605	COG0667	Aldo Keto reductase
GCU50_RS09610	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
GCU50_RS09620	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
GCU50_RS09630	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GCU50_RS09630	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GCU50_RS09640	COG4238	major outer membrane lipoprotein
GCU50_RS09645	COG3248	Nucleoside-binding outer membrane protein
GCU50_RS09660	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GCU50_RS09670	COG1862	Preprotein translocase
GCU50_RS09680	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
GCU50_RS09690	COG0450	alkyl hydroperoxide reductase
GCU50_RS09695	COG0366	Alpha amylase catalytic
GCU50_RS09715	COG5002	protein histidine kinase activity
GCU50_RS09725	COG0420	3'-5' exonuclease activity
GCU50_RS09730	COG0419	ATPase involved in DNA repair
GCU50_RS09735	COG1940	carbohydrate kinase activity
GCU50_RS09745	COG3123	guanosine phosphorylase activity
GCU50_RS09750	COG4126	flavin adenine dinucleotide binding
GCU50_RS09760	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
GCU50_RS09770	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
GCU50_RS09785	COG1785	Belongs to the alkaline phosphatase family
GCU50_RS09805	COG1181	Belongs to the D-alanine--D-alanine ligase family
GCU50_RS09825	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
GCU50_RS09835	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
GCU50_RS09840	COG0113	porphobilinogen synthase activity
GCU50_RS09850	COG0531	amino acid
GCU50_RS09860	COG4302	ethanolamine ammonia-lyase activity
GCU50_RS09865	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GCU50_RS09880	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
GCU50_RS09885	COG4948	Mandelate Racemase Muconate Lactonizing
GCU50_RS09920	COG0583	DNA-binding transcription factor activity
GCU50_RS09930	COG2308	Evidence 4 Homologs of previously reported genes of
GCU50_RS09965	COG4221	oxidoreductase activity
GCU50_RS09970	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
GCU50_RS09990	COG1309	transcriptional regulator
GCU50_RS10010	COG3272	Protein of unknown function (DUF1722)
GCU50_RS10015	COG0789	Transcriptional regulator
GCU50_RS10025	COG2205	protein histidine kinase activity
GCU50_RS10030	COG0745	RESPONSE REGULATOR receiver
GCU50_RS10035	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
GCU50_RS10040	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
GCU50_RS10105	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
GCU50_RS10110	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
GCU50_RS10115	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
GCU50_RS10135	COG2195	Cleaves the N-terminal amino acid of tripeptides
GCU50_RS10145	COG3034	peptidoglycan biosynthetic process
GCU50_RS10150	COG0121	glutamine amidotransferase
GCU50_RS10165	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
GCU50_RS10175	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GCU50_RS10190	COG4608	Belongs to the ABC transporter superfamily
GCU50_RS10195	COG0444	Belongs to the ABC transporter superfamily
GCU50_RS10205	COG2084	Dehydrogenase
GCU50_RS10220	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
GCU50_RS10225	COG0720	synthase
GCU50_RS10230	COG0602	queuosine metabolic process
GCU50_RS10250	COG3956	TIGRFAM MazG family protein
GCU50_RS10255	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
GCU50_RS10260	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GCU50_RS10265	COG3437	response regulator, receiver
GCU50_RS10265	COG3850	Histidine kinase
GCU50_RS10265	COG4999	Histidine kinase
GCU50_RS10265	COG2205	protein histidine kinase activity
GCU50_RS10270	COG1929	Belongs to the glycerate kinase type-1 family
GCU50_RS10300	COG3188	usher protein
GCU50_RS10320	COG4948	Mandelate Racemase Muconate Lactonizing
GCU50_RS10325	COG4948	Mandelate Racemase Muconate Lactonizing
GCU50_RS10330	COG2271	Major facilitator Superfamily
GCU50_RS10335	COG0716	FMN binding
GCU50_RS10340	COG0564	pseudouridine synthase activity
GCU50_RS10345	COG3098	single-species biofilm formation
GCU50_RS10365	COG1611	Belongs to the LOG family
GCU50_RS10370	COG0814	amino acid
GCU50_RS10375	COG1760	l-serine dehydratase
GCU50_RS10390	COG3188	usher protein
GCU50_RS10445	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
GCU50_RS10455	COG1580	Controls the rotational direction of flagella during chemotaxis
GCU50_RS10470	COG1157	protein secretion by the type III secretion system
GCU50_RS10475	COG1317	bacterial-type flagellum organization
GCU50_RS10480	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
GCU50_RS10485	COG1766	The M ring may be actively involved in energy transduction
GCU50_RS10490	COG1677	Flagellar hook-basal body complex protein FliE
GCU50_RS10495	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
GCU50_RS10500	COG2201	protein-glutamate methylesterase activity
GCU50_RS10505	COG0745	RESPONSE REGULATOR receiver
GCU50_RS10520	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
GCU50_RS10550	COG0835	chemotaxis
GCU50_RS10580	COG0840	transmembrane signaling receptor activity
GCU50_RS10585	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
GCU50_RS10590	COG1256	bacterial-type flagellum assembly
GCU50_RS10620	COG1749	Flagellar hook protein flgE
GCU50_RS10635	COG1815	bacterial-type flagellum-dependent cell motility
GCU50_RS10665	COG0840	transmembrane signaling receptor activity
GCU50_RS10665	COG2203	Gaf domain
GCU50_RS10670	COG0840	transmembrane signaling receptor activity
GCU50_RS10725	COG1566	PFAM secretion protein HlyD family protein
GCU50_RS10730	COG1289	transmembrane transporter activity
GCU50_RS10755	COG2226	methyltransferase
GCU50_RS10765	COG1388	LysM domain
GCU50_RS10765	COG0741	lytic transglycosylase activity
GCU50_RS10770	COG3021	interspecies interaction between organisms
GCU50_RS10775	COG0583	DNA-binding transcription factor activity
GCU50_RS10780	COG0656	L-ascorbic acid biosynthetic process
GCU50_RS10800	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GCU50_RS10830	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
GCU50_RS10840	COG2011	ABC-type metal ion transport system permease component
GCU50_RS10845	COG1464	Belongs to the NlpA lipoprotein family
GCU50_RS10855	COG1720	tRNA m6t6A37 methyltransferase activity
GCU50_RS10865	COG3015	lipoprotein NlpE involved in copper resistance
GCU50_RS10870	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
GCU50_RS10885	COG4568	rho-dependent transcription termination
GCU50_RS10890	COG0037	tRNA processing
GCU50_RS10895	COG0346	lactoylglutathione lyase activity
GCU50_RS10900	COG1982	Orn Lys Arg decarboxylase major
GCU50_RS10910	COG0587	DNA-directed DNA polymerase activity
GCU50_RS10930	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
GCU50_RS10940	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
GCU50_RS10945	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GCU50_RS10955	COG0575	Belongs to the CDS family
GCU50_RS10965	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
GCU50_RS10980	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
GCU50_RS11010	COG3835	regulator
GCU50_RS11030	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GCU50_RS11035	COG2860	membrane
GCU50_RS11060	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GCU50_RS11065	COG1120	ATPase activity
GCU50_RS11070	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GCU50_RS11075	COG1643	Atp-dependent helicase
GCU50_RS11080	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
GCU50_RS11100	COG0617	tRNA 3'-terminal CCA addition
GCU50_RS11105	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
GCU50_RS11110	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
GCU50_RS11115	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
GCU50_RS11125	COG0726	polysaccharide deacetylase
GCU50_RS11130	COG0842	Transport permease protein
GCU50_RS11135	COG1131	(ABC) transporter
GCU50_RS11140	COG0288	reversible hydration of carbon dioxide
GCU50_RS11150	COG4993	Dehydrogenase
GCU50_RS11155	COG2132	Multicopper oxidase
GCU50_RS11190	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GCU50_RS11195	COG0508	dehydrogenase complex catalyzes the overall conversion of
GCU50_RS11200	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
GCU50_RS11205	COG2186	Transcriptional regulator
GCU50_RS11210	COG1113	amino acid transport
GCU50_RS11215	COG3725	Membrane protein required for beta-lactamase induction
GCU50_RS11230	COG4969	Belongs to the N-Me-Phe pilin family
GCU50_RS11235	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
GCU50_RS11240	COG1459	type II secretion system
GCU50_RS11265	COG0494	nUDIX hydrolase
GCU50_RS11285	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
GCU50_RS11290	COG0849	cell division
GCU50_RS11315	COG0772	Belongs to the SEDS family
GCU50_RS11330	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
GCU50_RS11335	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
GCU50_RS11340	COG0768	penicillin binding
GCU50_RS11370	COG0028	Belongs to the TPP enzyme family
GCU50_RS11405	COG2814	Major facilitator Superfamily
GCU50_RS11425	COG1178	ABC-type Fe3 transport system permease component
GCU50_RS11435	COG0586	Pfam SNARE associated Golgi protein
GCU50_RS11450	COG2160	L-arabinose isomerase activity
GCU50_RS11455	COG0235	Class ii aldolase
GCU50_RS11460	COG0417	DNA replication proofreading
GCU50_RS11465	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
GCU50_RS11480	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
GCU50_RS11485	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GCU50_RS11500	COG2967	ApaG domain
GCU50_RS11510	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
GCU50_RS11535	COG0505	Belongs to the CarA family
GCU50_RS11560	COG1047	Peptidyl-prolyl cis-trans
GCU50_RS11575	COG0196	riboflavin kinase activity
GCU50_RS11590	COG0583	DNA-binding transcription factor activity
GCU50_RS11610	COG1584	GPR1 FUN34 yaaH family protein
GCU50_RS11620	COG0521	Mo-molybdopterin cofactor biosynthetic process
GCU50_RS11630	COG1115	amino acid carrier protein
GCU50_RS11645	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
GCU50_RS11655	COG0527	aspartate kinase activity
GCU50_RS11655	COG0460	homoserine dehydrogenase
GCU50_RS11665	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
GCU50_RS11675	COG0745	RESPONSE REGULATOR receiver
GCU50_RS11680	COG3045	CreA protein
GCU50_RS11685	COG3708	Transcriptional regulator
GCU50_RS11685	COG2207	Transcriptional regulator
GCU50_RS11700	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
GCU50_RS11705	COG0741	lytic transglycosylase activity
GCU50_RS11710	COG0488	(ABC) transporter
GCU50_RS11720	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
GCU50_RS11725	COG0560	Phosphoserine phosphatase
GCU50_RS11730	COG3726	membrane protein affecting hemolysin expression
GCU50_RS11760	COG1328	CTP reductase activity
GCU50_RS11765	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
GCU50_RS11770	COG0084	hydrolase, TatD family'
GCU50_RS11775	COG4667	esterase of the alpha-beta hydrolase superfamily
GCU50_RS11785	COG2823	Periplasmic or secreted lipoprotein
GCU50_RS11795	COG1011	Hydrolase
GCU50_RS11800	COG0456	acetyltransferase
GCU50_RS11805	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
GCU50_RS11840	COG4114	ferric iron reductase
GCU50_RS11845	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GCU50_RS11850	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
GCU50_RS11855	COG2197	response regulator
GCU50_RS11865	COG2966	Psort location CytoplasmicMembrane, score
GCU50_RS11875	COG1846	Transcriptional regulator
GCU50_RS11880	COG1764	response to oxidative stress
GCU50_RS11890	COG1484	DNA-dependent DNA replication
GCU50_RS11910	COG0840	transmembrane signaling receptor activity
GCU50_RS11915	COG1966	Carbon starvation protein
GCU50_RS11920	COG2879	small protein
GCU50_RS11925	COG0523	cobalamin synthesis protein
GCU50_RS11935	COG1012	belongs to the aldehyde dehydrogenase family
GCU50_RS11945	COG1473	amidohydrolase
GCU50_RS11950	COG0700	Nucleoside recognition
GCU50_RS11955	COG3366	ferrous iron transmembrane transporter activity
GCU50_RS11960	COG0583	DNA-binding transcription factor activity
GCU50_RS11975	COG2733	membrane
GCU50_RS11980	COG1775	2-hydroxyglutaryl-CoA dehydratase, D-component
GCU50_RS11985	COG1924	4 iron, 4 sulfur cluster binding
GCU50_RS12025	COG0740	serine-type endopeptidase activity
GCU50_RS12030	COG5457	Domain of unknown function (DUF1127)
GCU50_RS12035	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GCU50_RS12040	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
GCU50_RS12045	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GCU50_RS12045	COG1263	PTS System
GCU50_RS12055	COG1917	Cupin 2, conserved barrel domain protein
GCU50_RS12055	COG4977	sequence-specific DNA binding
GCU50_RS12060	COG0583	DNA-binding transcription factor activity
GCU50_RS12080	COG1737	Transcriptional regulator
GCU50_RS12090	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GCU50_RS12095	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GCU50_RS12100	COG1120	ATPase activity
GCU50_RS12105	COG4774	siderophore transport
GCU50_RS12110	COG1175	transmembrane transport
GCU50_RS12115	COG0395	ABC-type sugar transport system, permease component
GCU50_RS12120	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
GCU50_RS12125	COG3842	ATPase activity
GCU50_RS12130	COG1653	transport
GCU50_RS12150	COG2259	Doxx family
GCU50_RS12170	COG1733	regulation of RNA biosynthetic process
GCU50_RS12190	COG0583	DNA-binding transcription factor activity
GCU50_RS12195	COG4772	TonB-dependent receptor
GCU50_RS12220	COG2814	Major facilitator Superfamily
GCU50_RS12225	COG4264	IucA IucC family
GCU50_RS12230	COG0019	diaminopimelate decarboxylase activity
GCU50_RS12235	COG0583	DNA-binding transcription factor activity
GCU50_RS12250	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
GCU50_RS12255	COG1028	Short-chain dehydrogenase reductase Sdr
GCU50_RS12265	COG0702	epimerase
GCU50_RS12270	COG0583	DNA-binding transcription factor activity
GCU50_RS12280	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GCU50_RS12300	COG0583	DNA-binding transcription factor activity
GCU50_RS12310	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
GCU50_RS12315	COG2207	Transcriptional regulator
GCU50_RS12365	COG0604	alcohol dehydrogenase
GCU50_RS12385	COG1902	pentaerythritol trinitrate reductase activity
GCU50_RS12390	COG1309	transcriptional regulator
GCU50_RS12400	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GCU50_RS12405	COG3321	synthase
GCU50_RS12405	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GCU50_RS12405	COG4221	oxidoreductase activity
GCU50_RS12405	COG1028	Short-chain dehydrogenase reductase Sdr
GCU50_RS12430	COG1396	sequence-specific DNA binding
GCU50_RS12450	COG2040	homocysteine
GCU50_RS12455	COG0833	amino acid
GCU50_RS12475	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GCU50_RS12480	COG0765	amino acid transport
GCU50_RS12485	COG0765	amino acid transport
GCU50_RS12505	COG1028	Short-chain dehydrogenase reductase Sdr
GCU50_RS12515	COG0840	transmembrane signaling receptor activity
GCU50_RS12660	COG2003	Belongs to the UPF0758 family
GCU50_RS12690	COG4735	regulation of single-species biofilm formation
GCU50_RS12720	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
GCU50_RS12725	COG0732	type I restriction modification DNA specificity domain
GCU50_RS12735	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
GCU50_RS12750	COG0582	viral genome integration into host DNA
GCU50_RS12760	COG2197	response regulator
GCU50_RS12795	COG1064	alcohol dehydrogenase
GCU50_RS12805	COG0795	lipopolysaccharide-transporting ATPase activity
GCU50_RS12810	COG0795	lipopolysaccharide-transporting ATPase activity
GCU50_RS12815	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
GCU50_RS12820	COG2927	DNA polymerase III (CHI subunit)
GCU50_RS12855	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
GCU50_RS12860	COG2731	YhcH YjgK YiaL family protein
GCU50_RS12890	COG0251	oxidation-reduction process
GCU50_RS12910	COG1263	PTS System
GCU50_RS12910	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GCU50_RS12915	COG0366	Alpha amylase catalytic
GCU50_RS12925	COG0602	queuosine metabolic process
GCU50_RS12935	COG2207	Transcriptional regulator
GCU50_RS12940	COG0300	oxidoreductase activity
GCU50_RS12945	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GCU50_RS12945	COG3711	transcriptional antiterminator
GCU50_RS12950	COG2706	6-phosphogluconolactonase activity
GCU50_RS12965	COG3964	amidohydrolase
GCU50_RS13000	COG0312	modulator of DNA gyrase
GCU50_RS13015	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
GCU50_RS13030	COG0840	transmembrane signaling receptor activity
GCU50_RS13035	COG1172	Belongs to the binding-protein-dependent transport system permease family
GCU50_RS13040	COG1172	Belongs to the binding-protein-dependent transport system permease family
GCU50_RS13045	COG1129	ABC transporter
GCU50_RS13050	COG1879	ABC-type sugar transport system periplasmic component
GCU50_RS13065	COG2105	PFAM AIG2 family protein
GCU50_RS13070	COG2911	Protein conserved in bacteria
GCU50_RS13075	COG0729	surface antigen
GCU50_RS13080	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GCU50_RS13085	COG1253	flavin adenine dinucleotide binding
GCU50_RS13095	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
GCU50_RS13100	COG1218	3'(2'),5'-bisphosphate nucleotidase
GCU50_RS13110	COG1733	regulation of RNA biosynthetic process
GCU50_RS13115	COG0702	epimerase
GCU50_RS13125	COG0697	spore germination
GCU50_RS13130	COG0840	transmembrane signaling receptor activity
GCU50_RS13140	COG1113	amino acid transport
GCU50_RS13145	COG0545	Peptidyl-prolyl cis-trans isomerase
GCU50_RS13150	COG3061	Opacity-associated protein A
GCU50_RS13160	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
GCU50_RS13165	COG2965	DNA replication, synthesis of RNA primer
GCU50_RS13220	COG1073	alpha beta
GCU50_RS13225	COG3650	response to hydrogen peroxide
GCU50_RS13240	COG1960	acyl-CoA dehydrogenase activity
GCU50_RS13245	COG0477	Major facilitator Superfamily
GCU50_RS13250	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GCU50_RS13260	COG0557	exoribonuclease II activity
GCU50_RS13275	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
GCU50_RS13280	COG0330	HflC and HflK could
GCU50_RS13285	COG0330	HflC and HflK could
GCU50_RS13290	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
GCU50_RS13300	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
GCU50_RS13310	COG0860	N-Acetylmuramoyl-L-alanine amidase
GCU50_RS13315	COG0802	atpase or kinase
GCU50_RS13320	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
GCU50_RS13320	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
GCU50_RS13325	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
GCU50_RS13360	COG1511	domain protein
GCU50_RS13360	COG3264	Mechanosensitive ion channel
GCU50_RS13370	COG1053	succinate dehydrogenase
GCU50_RS13375	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
GCU50_RS13380	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
GCU50_RS13450	COG1509	lysine 2,3-aminomutase activity
GCU50_RS13475	COG0531	amino acid
GCU50_RS13480	COG3030	protein affecting phage T7 exclusion by the F plasmid
GCU50_RS13485	COG1027	Aspartate ammonia-lyase
GCU50_RS13490	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
GCU50_RS13505	COG1309	transcriptional regulator
GCU50_RS13530	COG2885	chlorophyll binding
GCU50_RS13555	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GCU50_RS13585	COG0148	phosphopyruvate hydratase activity
GCU50_RS13590	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
GCU50_RS13625	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
GCU50_RS13630	COG0477	Major facilitator Superfamily
GCU50_RS13640	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
GCU50_RS13645	COG2824	Alkylphosphonate utilization operon protein PhnA
GCU50_RS13655	COG2188	Transcriptional regulator
GCU50_RS13660	COG3624	Phosphonate C-P lyase system protein PhnG
GCU50_RS13665	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
GCU50_RS13670	COG3626	phosphonate metabolism
GCU50_RS13675	COG3627	carbon phosphorus lyase activity
GCU50_RS13680	COG4107	phosphonate C-P lyase system protein PhnK
GCU50_RS13685	COG4778	phosphonate C-P lyase system protein PhnL
GCU50_RS13690	COG3454	Phosphonate metabolism
GCU50_RS13695	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
GCU50_RS13700	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
GCU50_RS13735	COG1129	ABC transporter
GCU50_RS13740	COG1172	Belongs to the binding-protein-dependent transport system permease family
GCU50_RS13755	COG0191	fructose-bisphosphate aldolase activity
GCU50_RS13760	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GCU50_RS13775	COG0768	penicillin binding
GCU50_RS13780	COG2814	Major facilitator Superfamily
GCU50_RS13785	COG1301	dicarboxylic acid transport
GCU50_RS13795	COG3162	membrane
GCU50_RS13800	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GCU50_RS13805	COG1403	HNH endonuclease
GCU50_RS13815	COG1454	alcohol dehydrogenase
GCU50_RS13820	COG0583	DNA-binding transcription factor activity
GCU50_RS13850	COG0025	NhaP-type Na H and K H
GCU50_RS13855	COG2252	PERMEase
GCU50_RS13860	COG0789	Transcriptional regulator
GCU50_RS13870	COG4943	cyclic-guanylate-specific phosphodiesterase activity
GCU50_RS13905	COG3842	ATPase activity
GCU50_RS13910	COG1234	tRNA 3'-trailer cleavage
GCU50_RS13915	COG1609	Transcriptional regulator
GCU50_RS13920	COG0483	inositol monophosphate 1-phosphatase activity
GCU50_RS13960	COG0765	amino acid transport
GCU50_RS13965	COG1126	abc transporter atp-binding protein
GCU50_RS13970	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GCU50_RS13975	COG1605	Chorismate mutase
GCU50_RS13990	COG2315	Protein conserved in bacteria
GCU50_RS13995	COG0432	Pfam Uncharacterised protein family UPF0047
GCU50_RS14005	COG1448	Aminotransferase
GCU50_RS14015	COG0305	Participates in initiation and elongation during chromosome replication
GCU50_RS14030	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
GCU50_RS14045	COG0735	belongs to the Fur family
GCU50_RS14050	COG3237	CsbD-like
GCU50_RS14055	COG0534	Mate efflux family protein
GCU50_RS14065	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
GCU50_RS14080	COG3161	chorismate lyase activity
GCU50_RS14100	COG2182	Extracellular solute-binding protein
GCU50_RS14110	COG3833	ABC-type maltose transport systems, permease component
GCU50_RS14115	COG3223	Belongs to the PsiE family
GCU50_RS14130	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GCU50_RS14155	COG0527	aspartate kinase activity
GCU50_RS14175	COG1187	pseudouridine synthase activity
GCU50_RS14180	COG1283	sodium-dependent phosphate transmembrane transporter activity
GCU50_RS14215	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
GCU50_RS14250	COG0151	Belongs to the GarS family
GCU50_RS14265	COG3678	ATP-independent chaperone mediated protein folding
GCU50_RS14300	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
GCU50_RS14315	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
GCU50_RS14320	COG2104	thiamine diphosphate biosynthetic process
GCU50_RS14330	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
GCU50_RS14345	COG1447	Phosphotransferase system cellobiose-specific component IIA
GCU50_RS14380	COG0250	Participates in transcription elongation, termination and antitermination
GCU50_RS14435	COG0812	UDP-N-acetylmuramate dehydrogenase activity
GCU50_RS14475	COG1739	Uncharacterized protein family UPF0029
GCU50_RS14500	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
GCU50_RS14515	COG0805	protein transport
GCU50_RS14525	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
GCU50_RS14530	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
GCU50_RS14535	COG3165	ubiquinone biosynthetic process from chorismate
GCU50_RS14545	COG1322	Protein conserved in bacteria
GCU50_RS14565	COG0583	DNA-binding transcription factor activity
GCU50_RS14575	COG0561	phosphatase activity
GCU50_RS14580	COG2267	carboxylic ester hydrolase activity
GCU50_RS14585	COG1280	lysine exporter protein (LysE YggA)
GCU50_RS14590	COG1280	lysine exporter protein (LysE YggA)
GCU50_RS14600	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
GCU50_RS14620	COG0210	DNA helicase
GCU50_RS14625	COG1011	Hydrolase
GCU50_RS14645	COG5567	small periplasmic lipoprotein
GCU50_RS14670	COG2959	enzyme of heme biosynthesis
GCU50_RS14675	COG3071	HemY protein
GCU50_RS14720	COG2244	polysaccharide biosynthetic process
GCU50_RS14725	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
GCU50_RS14730	COG0456	acetyltransferase
GCU50_RS14735	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
GCU50_RS14740	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
GCU50_RS14750	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
GCU50_RS14755	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
GCU50_RS14765	COG3118	belongs to the thioredoxin family
GCU50_RS14810	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
GCU50_RS14820	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
GCU50_RS14825	COG3978	acetolactate synthase activity
GCU50_RS14845	COG3085	chromosome segregation
GCU50_RS14920	COG0583	DNA-binding transcription factor activity
GCU50_RS14935	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
GCU50_RS14950	COG2207	Transcriptional regulator
GCU50_RS14960	COG0371	Dehydrogenase
GCU50_RS14965	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
GCU50_RS14970	COG0527	aspartate kinase activity
GCU50_RS14970	COG0460	homoserine dehydrogenase
GCU50_RS14975	COG0626	cystathionine gamma-synthase activity
GCU50_RS14990	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
GCU50_RS14995	COG1609	Transcriptional regulator
GCU50_RS15000	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
GCU50_RS15015	COG1575	Belongs to the MenA family. Type 1 subfamily
GCU50_RS15020	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
GCU50_RS15025	COG3074	FtsZ-dependent cytokinesis
GCU50_RS15030	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
GCU50_RS15040	COG1494	fructose-1,6-bisphosphatase
GCU50_RS15050	COG3152	Membrane
GCU50_RS15060	COG0149	triose-phosphate isomerase activity
GCU50_RS15075	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
GCU50_RS15200	COG4695	Portal protein
GCU50_RS15260	COG4974	Belongs to the 'phage' integrase family
GCU50_RS15275	COG3678	ATP-independent chaperone mediated protein folding
GCU50_RS15280	COG0745	RESPONSE REGULATOR receiver
GCU50_RS15285	COG2205	protein histidine kinase activity
GCU50_RS15290	COG2258	MOSC domain
GCU50_RS15295	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GCU50_RS15315	COG1917	Cupin 2, conserved barrel domain protein
GCU50_RS15315	COG4977	sequence-specific DNA binding
GCU50_RS15340	COG0235	Class ii aldolase
GCU50_RS15345	COG1454	alcohol dehydrogenase
GCU50_RS15375	COG0437	4 iron, 4 sulfur cluster binding
GCU50_RS15380	COG2864	formate dehydrogenase
GCU50_RS15400	COG0456	acetyltransferase
GCU50_RS15415	COG1011	Hydrolase
GCU50_RS15430	COG3852	Histidine kinase
GCU50_RS15445	COG0635	Involved in the biosynthesis of porphyrin-containing compound
GCU50_RS15465	COG0204	Acyl-transferase
GCU50_RS15475	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
GCU50_RS15480	COG3084	Protein conserved in bacteria
GCU50_RS15485	COG0746	molybdenum cofactor guanylyltransferase activity
GCU50_RS15490	COG1763	Mo-molybdopterin cofactor biosynthetic process
GCU50_RS15520	COG2186	Transcriptional regulator
GCU50_RS15525	COG0477	Major facilitator Superfamily
GCU50_RS15530	COG1609	Transcriptional regulator
GCU50_RS15535	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GCU50_RS15540	COG1879	ABC-type sugar transport system periplasmic component
GCU50_RS15545	COG1172	Belongs to the binding-protein-dependent transport system permease family
GCU50_RS15555	COG1869	D-ribose catabolic process
GCU50_RS15575	COG1522	sequence-specific DNA binding
GCU50_RS15580	COG0716	FMN binding
GCU50_RS15595	COG3312	ion transport
GCU50_RS15645	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
GCU50_RS15655	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
GCU50_RS15660	COG0573	inorganic phosphate transmembrane transporter activity
GCU50_RS15665	COG0581	inorganic phosphate transmembrane transporter activity
GCU50_RS15675	COG0704	Plays a role in the regulation of phosphate uptake
GCU50_RS15690	COG3180	Ammonia monooxygenase
GCU50_RS15720	COG4735	regulation of single-species biofilm formation
GCU50_RS15740	COG0725	ABC transporter, periplasmic molybdate-binding protein
GCU50_RS15765	COG2207	Transcriptional regulator
GCU50_RS15795	COG1609	Transcriptional regulator
GCU50_RS15805	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GCU50_RS15810	COG2723	6-phospho-beta-galactosidase activity
GCU50_RS15815	COG1447	Phosphotransferase system cellobiose-specific component IIA
GCU50_RS15820	COG4580	involved in the transport of maltose and maltodextrins
GCU50_RS15825	COG0697	spore germination
GCU50_RS15840	COG0440	acetolactate synthase activity
GCU50_RS15845	COG0028	Belongs to the TPP enzyme family
GCU50_RS15865	COG2814	Major facilitator Superfamily
GCU50_RS15880	COG0641	radical SAM
GCU50_RS15890	COG2149	membrane
GCU50_RS15905	COG0071	Belongs to the small heat shock protein (HSP20) family
GCU50_RS15915	COG5645	(Lipo)protein
GCU50_RS15920	COG0823	Involved in the tonB-independent uptake of proteins
GCU50_RS15925	COG0561	phosphatase activity
GCU50_RS15935	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
GCU50_RS15940	COG0592	DNA-directed DNA polymerase activity
GCU50_RS15965	COG0706	membrane insertase activity
GCU50_RS15975	COG2091	lysine biosynthetic process via aminoadipic acid
GCU50_RS15980	COG0431	NADPH-dependent FMN reductase
GCU50_RS15985	COG2252	PERMEase
GCU50_RS15990	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GCU50_RS16000	COG3196	Protein conserved in bacteria
GCU50_RS16025	COG2211	Major facilitator Superfamily
GCU50_RS16030	COG1501	Belongs to the glycosyl hydrolase 31 family
GCU50_RS16035	COG2982	Protein involved in outer membrane biogenesis
GCU50_RS16040	COG2233	PERMEase
GCU50_RS16045	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
GCU50_RS16050	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GCU50_RS16055	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
GCU50_RS16075	COG1561	YicC-like family, N-terminal region
GCU50_RS16085	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
GCU50_RS16100	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
GCU50_RS16110	COG0227	Belongs to the bacterial ribosomal protein bL28 family
GCU50_RS16115	COG0267	Belongs to the bacterial ribosomal protein bL33 family
GCU50_RS16120	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
GCU50_RS16135	COG1519	Transferase
GCU50_RS16140	COG1216	Glycosyl transferase, family 2
GCU50_RS16145	COG0438	transferase activity, transferring glycosyl groups
GCU50_RS16150	COG0438	transferase activity, transferring glycosyl groups
GCU50_RS16155	COG0859	PFAM glycosyl transferase family 9
GCU50_RS16185	COG0859	PFAM glycosyl transferase family 9
GCU50_RS16205	COG2861	carbohydrate metabolic process
GCU50_RS16210	COG4942	peptidase
GCU50_RS16220	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GCU50_RS16225	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
GCU50_RS16245	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
GCU50_RS16255	COG2186	Transcriptional regulator
GCU50_RS16270	COG3722	fumarate hydratase activity
GCU50_RS16285	COG0625	glutathione transferase activity
GCU50_RS16295	COG3276	selenocysteine insertion sequence binding
GCU50_RS16300	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
GCU50_RS16305	COG3977	Valine--pyruvate aminotransferase
GCU50_RS16310	COG0366	Alpha amylase catalytic
GCU50_RS16315	COG2992	FlgJ-related protein
GCU50_RS16320	COG1609	Transcriptional regulator
GCU50_RS16320	COG2207	Transcriptional regulator
GCU50_RS16325	COG4214	carbohydrate transport
GCU50_RS16335	COG4213	ABC transporter substrate-binding protein
GCU50_RS16340	COG2115	Belongs to the xylose isomerase family
GCU50_RS16345	COG1070	Carbohydrate kinase
GCU50_RS16360	COG3274	enterobacterial common antigen metabolic process
GCU50_RS16380	COG5001	Diguanylate cyclase
GCU50_RS16380	COG4251	negative regulation of phosphorylation
GCU50_RS16380	COG3706	GGDEF domain
GCU50_RS16380	COG2203	Gaf domain
GCU50_RS16385	COG1776	CheC inhibitor of MCP methylation
GCU50_RS16390	COG2197	response regulator
GCU50_RS16395	COG2944	sequence-specific DNA binding
GCU50_RS16415	COG2814	Major facilitator Superfamily
GCU50_RS16420	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GCU50_RS16430	COG1609	Transcriptional regulator
GCU50_RS16435	COG0243	molybdopterin cofactor binding
GCU50_RS16440	COG0456	acetyltransferase
GCU50_RS16445	COG2818	Glycosylase
GCU50_RS16450	COG5571	outer membrane autotransporter
GCU50_RS16455	COG2223	nitrite transmembrane transporter activity
GCU50_RS16460	COG1764	response to oxidative stress
GCU50_RS16480	COG0747	negative chemotaxis
GCU50_RS16485	COG0601	transmembrane transport
GCU50_RS16490	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GCU50_RS16495	COG0444	Belongs to the ABC transporter superfamily
GCU50_RS16500	COG4608	Belongs to the ABC transporter superfamily
GCU50_RS16525	COG1215	transferase activity, transferring glycosyl groups
GCU50_RS16545	COG2194	sulfuric ester hydrolase activity
GCU50_RS16565	COG1192	Involved in chromosome partitioning
GCU50_RS16575	COG1215	transferase activity, transferring glycosyl groups
GCU50_RS16585	COG0457	Tetratricopeptide repeat
GCU50_RS16585	COG3118	belongs to the thioredoxin family
GCU50_RS16590	COG2199	diguanylate cyclase activity
GCU50_RS16590	COG2200	EAL domain
GCU50_RS16600	COG0612	Peptidase, M16
GCU50_RS16610	COG2200	EAL domain
GCU50_RS16615	COG2982	Protein involved in outer membrane biogenesis
GCU50_RS16620	COG0477	Major facilitator Superfamily
GCU50_RS16630	COG1295	ribonuclease BN
GCU50_RS16635	COG0583	DNA-binding transcription factor activity
GCU50_RS16640	COG1028	Short-chain dehydrogenase reductase Sdr
GCU50_RS16645	COG3111	PFAM Bacterial OB fold (BOF) protein
GCU50_RS16650	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GCU50_RS16670	COG2957	Belongs to the agmatine deiminase family
GCU50_RS16675	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
GCU50_RS16685	COG0406	alpha-ribazole phosphatase activity
GCU50_RS16690	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GCU50_RS16695	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
GCU50_RS16700	COG0671	phosphoesterase, PA-phosphatase related
GCU50_RS16705	COG0339	signal peptide processing
GCU50_RS16725	COG0306	phosphate transporter
GCU50_RS16730	COG2081	HI0933 family
GCU50_RS16745	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
GCU50_RS16765	COG3209	COG3209 Rhs family protein
GCU50_RS16765	COG4104	PAAR repeat-containing protein
GCU50_RS16815	COG0679	Auxin Efflux Carrier
GCU50_RS16820	COG1028	Short-chain dehydrogenase reductase Sdr
GCU50_RS16840	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GCU50_RS16845	COG0601	transmembrane transport
GCU50_RS16850	COG0747	negative chemotaxis
GCU50_RS16860	COG3479	Phenolic acid decarboxylase
GCU50_RS16900	COG0628	permease
GCU50_RS16905	COG0477	Major facilitator Superfamily
GCU50_RS16915	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
GCU50_RS16930	COG3714	YhhN family
GCU50_RS16940	COG3776	membrane
GCU50_RS16945	COG0742	ribosomal rna small subunit methyltransferase
GCU50_RS16950	COG0552	protein localization to endoplasmic reticulum
GCU50_RS16955	COG2884	Cell division ATP-binding protein ftsE
GCU50_RS16960	COG2177	Part of the ABC transporter FtsEX involved in
GCU50_RS16965	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
GCU50_RS16975	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
GCU50_RS16985	COG0456	acetyltransferase
GCU50_RS16990	COG0683	leucine binding
GCU50_RS17005	COG0411	ABC transporter
GCU50_RS17035	COG0584	glycerophosphoryl diester phosphodiesterase
GCU50_RS17045	COG0405	Gamma-glutamyltransferase
GCU50_RS17050	COG1247	-acetyltransferase
GCU50_RS17055	COG0673	inositol 2-dehydrogenase activity
GCU50_RS17060	COG1741	Belongs to the pirin family
GCU50_RS17065	COG1609	Transcriptional regulator
GCU50_RS17070	COG3265	gluconokinase activity
GCU50_RS17075	COG2610	gluconate transmembrane transporter activity
GCU50_RS17080	COG2095	MarC family integral membrane protein
GCU50_RS17085	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
GCU50_RS17095	COG1523	belongs to the glycosyl hydrolase 13 family
GCU50_RS17100	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
GCU50_RS17110	COG0058	SHG alpha-glucan phosphorylase activity
GCU50_RS17115	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
GCU50_RS17130	COG1349	DNA-binding transcription factor activity
GCU50_RS17135	COG2909	trisaccharide binding
GCU50_RS17140	COG0058	SHG alpha-glucan phosphorylase activity
GCU50_RS17145	COG1640	4-alpha-glucanotransferase
GCU50_RS17150	COG2610	gluconate transmembrane transporter activity
GCU50_RS17160	COG1040	competence protein
GCU50_RS17180	COG1918	ferrous iron import across plasma membrane
GCU50_RS17185	COG2183	response to ionizing radiation
GCU50_RS17190	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
GCU50_RS17215	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
GCU50_RS17220	COG1011	Hydrolase
GCU50_RS17230	COG0494	nUDIX hydrolase
GCU50_RS17235	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
GCU50_RS17240	COG4972	Pilus assembly protein
GCU50_RS17245	COG3166	PFAM Fimbrial assembly family protein
GCU50_RS17260	COG4796	Type ii and iii secretion system protein
GCU50_RS17275	COG3266	domain, Protein
GCU50_RS17280	COG0338	D12 class N6 adenine-specific DNA methyltransferase
GCU50_RS17285	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
GCU50_RS17310	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
GCU50_RS17320	COG0402	S-adenosylhomocysteine deaminase activity
GCU50_RS17345	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
GCU50_RS17350	COG1289	transmembrane transporter activity
GCU50_RS17355	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GCU50_RS17360	COG1765	OsmC-like protein
GCU50_RS17365	COG3954	Phosphoribulokinase
GCU50_RS17375	COG0429	hydrolase of the alpha beta-hydrolase fold
GCU50_RS17425	COG0679	Auxin Efflux Carrier
GCU50_RS17445	COG0488	(ABC) transporter
GCU50_RS17450	COG2249	NAD(P)H dehydrogenase (quinone) activity
GCU50_RS17455	COG0475	glutathione-regulated potassium exporter activity
GCU50_RS17455	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
GCU50_RS17460	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
GCU50_RS17465	COG1047	Peptidyl-prolyl cis-trans
GCU50_RS17475	COG0545	Peptidyl-prolyl cis-trans isomerase
GCU50_RS17480	COG2964	Protein conserved in bacteria
GCU50_RS17535	COG0051	transcription antitermination factor activity, RNA binding
GCU50_RS17560	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
GCU50_RS17575	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
GCU50_RS17625	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
GCU50_RS17635	COG0200	Binds to the 23S rRNA
GCU50_RS17640	COG0201	protein transport
GCU50_RS17680	COG0789	Transcriptional regulator
GCU50_RS17685	COG3036	rescue of stalled ribosome
GCU50_RS17715	COG0758	DNA mediated transformation
GCU50_RS17725	COG0551	DNA topoisomerase type I activity
GCU50_RS17745	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
GCU50_RS17785	COG1126	abc transporter atp-binding protein
GCU50_RS17790	COG0765	amino acid transport
GCU50_RS17795	COG4597	amino acid ABC transporter
GCU50_RS17800	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GCU50_RS17815	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
GCU50_RS17825	COG4145	pantothenate transmembrane transporter activity
GCU50_RS17830	COG3924	membrane
GCU50_RS17835	COG0439	Biotin carboxylase
GCU50_RS17840	COG0511	ligase activity, forming carbon-carbon bonds
GCU50_RS17845	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
GCU50_RS17850	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
GCU50_RS17860	COG2199	diguanylate cyclase activity
GCU50_RS17860	COG2200	EAL domain
GCU50_RS17865	COG1077	Cell shape determining protein MreB Mrl
GCU50_RS17870	COG1792	Involved in formation and maintenance of cell shape
GCU50_RS17875	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
GCU50_RS17890	COG3164	Protein of unknown function
GCU50_RS17895	COG0312	modulator of DNA gyrase
GCU50_RS17900	COG0583	DNA-binding transcription factor activity
GCU50_RS17915	COG1289	transmembrane transporter activity
GCU50_RS17925	COG2732	(Barnase) inhibitor
GCU50_RS17955	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GCU50_RS17960	COG3105	Protein conserved in bacteria
GCU50_RS17965	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
GCU50_RS17980	COG0625	glutathione transferase activity
GCU50_RS17985	COG2969	positive regulation of protein catabolic process
GCU50_RS17990	COG0493	'glutamate synthase
GCU50_RS17995	COG0067	glutamate synthase
GCU50_RS17995	COG0070	glutamate synthase
GCU50_RS17995	COG0069	glutamate synthase activity
GCU50_RS18000	COG1242	4 iron, 4 sulfur cluster binding
GCU50_RS18005	COG5002	protein histidine kinase activity
GCU50_RS18005	COG0784	Response regulator, receiver
GCU50_RS18005	COG2198	Histidine kinase
GCU50_RS18010	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
GCU50_RS18020	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
GCU50_RS18025	COG1660	Displays ATPase and GTPase activities
GCU50_RS18035	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
GCU50_RS18045	COG1137	ATPase activity
GCU50_RS18050	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
GCU50_RS18055	COG3117	lipopolysaccharide transmembrane transporter activity
GCU50_RS18060	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
GCU50_RS18070	COG0530	calcium, potassium:sodium antiporter activity
GCU50_RS18075	COG1127	ABC transporter
GCU50_RS18080	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
GCU50_RS18085	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
GCU50_RS18090	COG2854	intermembrane phospholipid transfer
GCU50_RS18095	COG3113	response to antibiotic
GCU50_RS18100	COG5007	Belongs to the BolA IbaG family
GCU50_RS18110	COG3423	Transcriptional regulator
GCU50_RS18115	COG0142	geranyltranstransferase activity
GCU50_RS18130	COG0697	spore germination
GCU50_RS18140	COG2027	D-alanyl-D-alanine carboxypeptidase
GCU50_RS18150	COG1534	Rna-binding protein
GCU50_RS18155	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
GCU50_RS18165	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
GCU50_RS18170	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GCU50_RS18175	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
GCU50_RS18185	COG0137	argininosuccinate synthase activity
GCU50_RS18200	COG0195	Participates in both transcription termination and antitermination
GCU50_RS18240	COG0513	Belongs to the DEAD box helicase family
GCU50_RS18245	COG0814	amino acid
GCU50_RS18250	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GCU50_RS18255	COG0826	peptidase U32
GCU50_RS18260	COG0826	peptidase U32
GCU50_RS18265	COG3154	lipid carrier protein
GCU50_RS18270	COG3153	acetyltransferase
GCU50_RS18285	COG0693	protein deglycase activity
GCU50_RS18290	COG0702	epimerase
GCU50_RS18295	COG0701	Predicted permease
GCU50_RS18300	COG2823	Periplasmic or secreted lipoprotein
GCU50_RS18315	COG3107	peptidoglycan biosynthetic process
GCU50_RS18320	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
GCU50_RS18325	COG2721	sulfolactate sulfo-lyase activity
GCU50_RS18330	COG2271	Major facilitator Superfamily
GCU50_RS18340	COG2084	Dehydrogenase
GCU50_RS18345	COG1929	Belongs to the glycerate kinase type-1 family
GCU50_RS18355	COG1741	Belongs to the pirin family
GCU50_RS18360	COG0583	DNA-binding transcription factor activity
GCU50_RS18365	COG3152	Membrane
GCU50_RS18370	COG0435	Glutathione S-transferase
GCU50_RS18375	COG2259	Doxx family
GCU50_RS18385	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
GCU50_RS18390	COG4575	ribosome binding
GCU50_RS18395	COG1422	Protein of unknown function (DUF1090)
GCU50_RS18405	COG0586	Pfam SNARE associated Golgi protein
GCU50_RS18410	COG2186	Transcriptional regulator
GCU50_RS18415	COG2271	Major facilitator Superfamily
GCU50_RS18425	COG2721	sulfolactate sulfo-lyase activity
GCU50_RS18435	COG0861	Integral membrane protein TerC family
GCU50_RS18440	COG0673	inositol 2-dehydrogenase activity
GCU50_RS18450	COG1522	sequence-specific DNA binding
GCU50_RS18455	COG1451	nucleotide metabolic process
GCU50_RS18465	COG1902	pentaerythritol trinitrate reductase activity
GCU50_RS18465	COG0446	pyridine nucleotide-disulphide oxidoreductase
GCU50_RS18470	COG1070	Carbohydrate kinase
GCU50_RS18475	COG1830	Aldolase
GCU50_RS18490	COG0840	transmembrane signaling receptor activity
GCU50_RS18495	COG0840	transmembrane signaling receptor activity
GCU50_RS18500	COG1695	Transcriptional regulator
GCU50_RS18505	COG2375	cellular response to nickel ion
GCU50_RS18515	COG1028	Short-chain dehydrogenase reductase Sdr
GCU50_RS18525	COG0840	transmembrane signaling receptor activity
GCU50_RS18530	COG0582	viral genome integration into host DNA
GCU50_RS18545	COG3561	AntA/AntB antirepressor
GCU50_RS18640	COG3663	DNA glycosylase
GCU50_RS18650	COG0358	DNA primase activity
GCU50_RS18655	COG0828	Belongs to the bacterial ribosomal protein bS21 family
GCU50_RS18670	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
GCU50_RS18680	COG0617	tRNA 3'-terminal CCA addition
GCU50_RS18685	COG4991	sh3 domain protein
GCU50_RS18690	COG3025	triphosphatase activity
GCU50_RS18700	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
GCU50_RS18700	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
GCU50_RS18720	COG3384	dioxygenase
GCU50_RS18725	COG0754	glutathionylspermidine amidase activity
GCU50_RS18740	COG0494	nUDIX hydrolase
GCU50_RS18745	COG3151	Protein conserved in bacteria
GCU50_RS18750	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
GCU50_RS18755	COG3150	esterase
GCU50_RS18760	COG0187	DNA topoisomerase II activity
GCU50_RS18785	COG1174	glycine betaine transport
GCU50_RS18800	COG2986	histidine ammonia-lyase
GCU50_RS18810	COG2188	Transcriptional regulator
GCU50_RS18815	COG0402	S-adenosylhomocysteine deaminase activity
GCU50_RS18820	COG0400	carboxylic ester hydrolase activity
GCU50_RS18825	COG0435	Glutathione S-transferase
GCU50_RS18835	COG0583	DNA-binding transcription factor activity
GCU50_RS18840	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
GCU50_RS18845	COG2249	NAD(P)H dehydrogenase (quinone) activity
GCU50_RS18855	COG0204	Acyl-transferase
GCU50_RS18865	COG1032	radical SAM domain protein
GCU50_RS18875	COG1979	alcohol dehydrogenase
GCU50_RS18880	COG2207	Transcriptional regulator
GCU50_RS18900	COG0848	biopolymer transport protein
GCU50_RS18920	COG2862	Uncharacterized protein family, UPF0114
GCU50_RS18925	COG0667	Aldo Keto reductase
GCU50_RS18935	COG0840	transmembrane signaling receptor activity
GCU50_RS18945	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
GCU50_RS18950	COG0437	4 iron, 4 sulfur cluster binding
GCU50_RS18955	COG5557	Pfam Polysulphide reductase, NrfD
GCU50_RS18960	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
GCU50_RS18965	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
GCU50_RS18970	COG1773	rubredoxin
GCU50_RS18980	COG0298	carbon dioxide binding
GCU50_RS18985	COG0625	glutathione transferase activity
GCU50_RS19030	COG3615	Tellurite resistance protein tehB
GCU50_RS19040	COG3615	Tellurite resistance protein tehB
GCU50_RS19070	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
GCU50_RS19125	COG1278	Cold shock
GCU50_RS19140	COG1028	Short-chain dehydrogenase reductase Sdr
GCU50_RS19150	COG2217	Heavy metal translocating P-type atpase
GCU50_RS19180	COG1811	Na channel or pump
GCU50_RS19185	COG1982	Orn Lys Arg decarboxylase major
GCU50_RS19200	COG3493	citrate carrier protein
GCU50_RS19205	COG0179	Fumarylacetoacetate (FAA) hydrolase
GCU50_RS19215	COG3052	prosthetic group binding
GCU50_RS19235	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
GCU50_RS19240	COG2211	Major facilitator Superfamily
GCU50_RS19255	COG1194	a g-specific adenine glycosylase
GCU50_RS19265	COG3171	Protein conserved in bacteria
GCU50_RS19275	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
GCU50_RS19280	COG0635	Involved in the biosynthesis of porphyrin-containing compound
GCU50_RS19290	COG1872	DUF167
GCU50_RS19295	COG0762	integral membrane protein
GCU50_RS19300	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
GCU50_RS19305	COG2805	Type II/IV secretion system protein
GCU50_RS19310	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GCU50_RS19335	COG1385	rRNA (uridine-N3-)-methyltransferase activity
GCU50_RS19340	COG2356	endonuclease I
GCU50_RS19345	COG3091	SprT-like family
GCU50_RS19350	COG2814	Major facilitator Superfamily
GCU50_RS19365	COG1166	arginine decarboxylase activity
GCU50_RS19370	COG0501	Belongs to the peptidase M48B family
GCU50_RS19375	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
GCU50_RS19385	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
GCU50_RS19395	COG0191	fructose-bisphosphate aldolase activity
GCU50_RS19400	COG0668	transmembrane transport
GCU50_RS19405	COG1279	arginine transmembrane transporter activity
GCU50_RS19410	COG2968	Membrane
GCU50_RS19415	COG0583	DNA-binding transcription factor activity
GCU50_RS19425	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GCU50_RS19430	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
GCU50_RS19450	COG0006	proline dipeptidase activity
GCU50_RS19455	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GCU50_RS19460	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GCU50_RS19480	COG0477	Major facilitator Superfamily
GCU50_RS19485	COG1028	Short-chain dehydrogenase reductase Sdr
GCU50_RS19495	COG2723	6-phospho-beta-galactosidase activity
GCU50_RS19500	COG1737	Transcriptional regulator
GCU50_RS19505	COG1272	protein, Hemolysin III
GCU50_RS19525	COG0716	FMN binding
GCU50_RS19530	COG4974	Belongs to the 'phage' integrase family
GCU50_RS19540	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
GCU50_RS19555	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
GCU50_RS19565	COG4942	peptidase
GCU50_RS19660	COG3592	Divergent 4Fe-4S mono-cluster
GCU50_RS19665	COG2388	GCN5-related N-acetyl-transferase
GCU50_RS19675	COG2610	gluconate transmembrane transporter activity
GCU50_RS19680	COG1312	Catalyzes the dehydration of D-mannonate
GCU50_RS19700	COG2226	methyltransferase
GCU50_RS19705	COG2850	peptidyl-arginine hydroxylation
GCU50_RS19725	COG0583	DNA-binding transcription factor activity
GCU50_RS19730	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
GCU50_RS19735	COG1210	Utp--glucose-1-phosphate uridylyltransferase
GCU50_RS19740	COG5001	Diguanylate cyclase
GCU50_RS19740	COG3300	MHYT domain
GCU50_RS19750	COG0457	Tetratricopeptide repeat
GCU50_RS19755	COG1215	transferase activity, transferring glycosyl groups
GCU50_RS19760	COG1215	transferase activity, transferring glycosyl groups
GCU50_RS19770	COG2202	Pas domain
GCU50_RS19770	COG2199	diguanylate cyclase activity
GCU50_RS19770	COG2200	EAL domain
GCU50_RS19780	COG0626	cystathionine gamma-synthase activity
GCU50_RS19795	COG2011	ABC-type metal ion transport system permease component
GCU50_RS19800	COG1464	Belongs to the NlpA lipoprotein family
GCU50_RS19805	COG0183	Belongs to the thiolase family
GCU50_RS19810	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
GCU50_RS19815	COG0823	Involved in the tonB-independent uptake of proteins
GCU50_RS19825	COG1028	Short-chain dehydrogenase reductase Sdr
GCU50_RS19830	COG2814	Major facilitator Superfamily
GCU50_RS19835	COG0823	Involved in the tonB-independent uptake of proteins
GCU50_RS19845	COG3842	ATPase activity
GCU50_RS19850	COG0395	ABC-type sugar transport system, permease component
GCU50_RS19855	COG1175	transmembrane transport
GCU50_RS19865	COG1794	racemase activity, acting on amino acids and derivatives
GCU50_RS19870	COG0583	DNA-binding transcription factor activity
GCU50_RS19880	COG1609	Transcriptional regulator
GCU50_RS19885	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GCU50_RS19890	COG2723	6-phospho-beta-galactosidase activity
GCU50_RS19895	COG2186	Transcriptional regulator
GCU50_RS19905	COG1609	Transcriptional regulator
GCU50_RS19915	COG0477	Major facilitator Superfamily
GCU50_RS19920	COG0667	Aldo Keto reductase
GCU50_RS19930	COG0861	Integral membrane protein TerC family
GCU50_RS19945	COG0494	nUDIX hydrolase
GCU50_RS19965	COG2165	general secretion pathway protein
GCU50_RS19970	COG4795	General secretion pathway protein
GCU50_RS19980	COG4967	type IV pilus modification protein PilV
GCU50_RS19985	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
GCU50_RS19995	COG1074	ATP-dependent DNA helicase activity
GCU50_RS20000	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
GCU50_RS20005	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
GCU50_RS20005	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
GCU50_RS20010	COG0860	N-Acetylmuramoyl-L-alanine amidase
GCU50_RS20025	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
GCU50_RS20030	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
GCU50_RS20035	COG2166	iron-sulfur cluster assembly
GCU50_RS20040	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
GCU50_RS20050	COG0583	DNA-binding transcription factor activity
GCU50_RS20055	COG2363	Small membrane protein
GCU50_RS20070	COG2234	aminopeptidase activity
GCU50_RS20130	COG4942	peptidase
GCU50_RS20130	COG1388	LysM domain
GCU50_RS20135	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
GCU50_RS20150	COG0583	DNA-binding transcription factor activity
GCU50_RS20175	COG5001	Diguanylate cyclase
GCU50_RS20240	COG1028	Short-chain dehydrogenase reductase Sdr
GCU50_RS20250	COG2226	methyltransferase
GCU50_RS20305	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
GCU50_RS20360	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GCU50_RS20390	COG3707	response regulator
GCU50_RS20395	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
GCU50_RS20400	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GCU50_RS20405	COG1116	anion transmembrane transporter activity
GCU50_RS20410	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
GCU50_RS20410	COG2146	nitrite reductase [NAD(P)H] activity
GCU50_RS20415	COG0243	molybdopterin cofactor binding
GCU50_RS20450	COG0309	Hydrogenase expression formation protein (HypE)
GCU50_RS20455	COG0409	Hydrogenase expression formation protein
GCU50_RS20460	COG0298	carbon dioxide binding
GCU50_RS20465	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
GCU50_RS20470	COG0375	protein maturation
GCU50_RS20480	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
GCU50_RS20485	COG0651	ATP synthesis coupled electron transport
GCU50_RS20490	COG0650	Formate hydrogenlyase subunit 4
GCU50_RS20495	COG3261	NADH dehydrogenase
GCU50_RS20495	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
GCU50_RS20500	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GCU50_RS20505	COG3260	NADH ubiquinone oxidoreductase 20
GCU50_RS20515	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
GCU50_RS20520	COG3706	GGDEF domain
GCU50_RS20525	COG0583	DNA-binding transcription factor activity
GCU50_RS20530	COG0667	Aldo Keto reductase
GCU50_RS20535	COG1609	Transcriptional regulator
GCU50_RS20560	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
GCU50_RS20565	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
GCU50_RS20565	COG2169	Transcriptional regulator
GCU50_RS20570	COG2723	6-phospho-beta-galactosidase activity
GCU50_RS20575	COG1263	PTS System
GCU50_RS20575	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GCU50_RS20580	COG1609	Transcriptional regulator
GCU50_RS20585	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
GCU50_RS20590	COG3383	formate dehydrogenase (NAD+) activity
GCU50_RS20595	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
GCU50_RS20605	COG1773	rubredoxin
GCU50_RS20605	COG0426	domain, Protein
GCU50_RS20610	COG3604	Transcriptional regulator
GCU50_RS20620	COG1349	DNA-binding transcription factor activity
GCU50_RS20625	COG4578	phosphoenolpyruvate-dependent sugar phosphotransferase system
GCU50_RS20630	COG1028	Short-chain dehydrogenase reductase Sdr
GCU50_RS20640	COG3732	PTS system glucitol sorbitol-specific
GCU50_RS20645	COG3730	PTS system glucitol sorbitol-specific
GCU50_RS20650	COG2951	lytic endotransglycosylase activity
GCU50_RS20655	COG3711	transcriptional antiterminator
GCU50_RS20660	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GCU50_RS20660	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GCU50_RS20660	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GCU50_RS20665	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GCU50_RS20670	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GCU50_RS20670	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GCU50_RS20680	COG0191	fructose-bisphosphate aldolase activity
GCU50_RS20685	COG1940	carbohydrate kinase activity
GCU50_RS20700	COG1108	ABC-type Mn2 Zn2 transport systems permease components
GCU50_RS20710	COG1546	Belongs to the CinA family
GCU50_RS20730	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
GCU50_RS20760	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GCU50_RS20765	COG1238	metal cluster binding
GCU50_RS20770	COG2918	glutathione biosynthetic process
GCU50_RS20785	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
GCU50_RS20790	COG2814	Major facilitator Superfamily
GCU50_RS20795	COG1566	PFAM secretion protein HlyD family protein
GCU50_RS20800	COG1846	Transcriptional regulator
GCU50_RS20810	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
GCU50_RS20815	COG2814	Major facilitator Superfamily
GCU50_RS20825	COG4176	ABC-type proline glycine betaine transport system permease component
GCU50_RS20835	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GCU50_RS20850	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
GCU50_RS20855	COG4575	ribosome binding
GCU50_RS20875	COG0401	homolog of Blt101
GCU50_RS20890	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GCU50_RS20895	COG0640	Transcriptional regulator
GCU50_RS20935	COG3639	organic phosphonate transmembrane transporter activity
GCU50_RS20945	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
GCU50_RS20965	COG1175	transmembrane transport
GCU50_RS20970	COG3842	ATPase activity
GCU50_RS20995	COG2382	esterase
GCU50_RS21025	COG5001	Diguanylate cyclase
GCU50_RS21025	COG4251	negative regulation of phosphorylation
GCU50_RS21025	COG2203	Gaf domain
GCU50_RS21025	COG3706	GGDEF domain
GCU50_RS21030	COG0281	malic enzyme
GCU50_RS21035	COG0679	Auxin Efflux Carrier
GCU50_RS21040	COG3493	citrate carrier protein
GCU50_RS21095	COG0402	S-adenosylhomocysteine deaminase activity
GCU50_RS21100	COG0251	oxidation-reduction process
GCU50_RS21110	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
GCU50_RS21120	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GCU50_RS21160	COG2130	NADP-dependent
GCU50_RS21170	COG0583	DNA-binding transcription factor activity
GCU50_RS21200	COG3179	chitinase
GCU50_RS21265	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
GCU50_RS21265	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
GCU50_RS21330	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
GCU50_RS21335	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
GCU50_RS21370	COG1442	glycosyl transferase family 8
GCU50_RS21370	COG1216	Glycosyl transferase, family 2
GCU50_RS21395	COG2003	Belongs to the UPF0758 family
GCU50_RS21435	COG4735	regulation of single-species biofilm formation
GCU50_RS21450	COG3311	Transcriptional regulator
GCU50_RS21490	COG3547	Transposase (IS116 IS110 IS902 family)
GCU50_RS21495	COG0582	viral genome integration into host DNA
GCU50_RS21510	COG2867	negative regulation of translational initiation
GCU50_RS21520	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GCU50_RS21530	COG0497	DNA recombination
GCU50_RS21545	COG4536	flavin adenine dinucleotide binding
GCU50_RS21550	COG4137	Cytochrome C assembly protein
GCU50_RS21555	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
GCU50_RS21715	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
GCU50_RS21735	COG1605	Chorismate mutase
GCU50_RS21735	COG0287	Prephenate dehydrogenase
GCU50_RS21745	COG0077	Prephenate dehydratase
GCU50_RS21745	COG1605	Chorismate mutase
GCU50_RS21750	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
GCU50_RS21755	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GCU50_RS21765	COG1496	oxidoreductase activity
GCU50_RS21770	COG0542	response to heat
GCU50_RS21795	COG0477	Major facilitator Superfamily
GCU50_RS21800	COG5544	Lipoprotein
GCU50_RS21805	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GCU50_RS21815	COG3148	PFAM DTW domain containing protein
GCU50_RS21820	COG3118	belongs to the thioredoxin family
GCU50_RS21825	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GCU50_RS21840	COG0513	Belongs to the DEAD box helicase family
GCU50_RS21850	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
GCU50_RS21870	COG3086	response to oxidative stress
GCU50_RS21880	COG0681	Belongs to the peptidase S26 family
GCU50_RS21890	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
GCU50_RS21895	COG1381	Involved in DNA repair and RecF pathway recombination
GCU50_RS21900	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
GCU50_RS21910	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
GCU50_RS21915	COG1737	Transcriptional regulator
GCU50_RS21925	COG0560	Phosphoserine phosphatase
GCU50_RS21935	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
GCU50_RS21945	COG0047	phosphoribosylformylglycinamidine synthase activity
GCU50_RS21945	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
GCU50_RS21950	COG2205	protein histidine kinase activity
GCU50_RS21955	COG3170	Tfp pilus assembly protein FimV
GCU50_RS21960	COG2204	response regulator
GCU50_RS21965	COG0347	Belongs to the P(II) protein family
GCU50_RS21990	COG2814	Major facilitator Superfamily
GCU50_RS21995	COG3711	transcriptional antiterminator
GCU50_RS22000	COG3683	transport system, periplasmic component
GCU50_RS22005	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
GCU50_RS22030	COG0822	iron-sulfur transferase activity
GCU50_RS22050	COG0633	Ferredoxin
GCU50_RS22055	COG2975	iron-sulfur cluster assembly
GCU50_RS22070	COG1737	Transcriptional regulator
GCU50_RS22075	COG2897	thiosulfate sulfurtransferase activity
GCU50_RS22085	COG1263	PTS System
GCU50_RS22085	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GCU50_RS22085	COG2190	(PTS) system
GCU50_RS22090	COG2373	Large extracellular alpha-helical protein
GCU50_RS22095	COG4953	penicillin-binding protein 1C
GCU50_RS22110	COG1426	Protein conserved in bacteria
GCU50_RS22120	COG0124	histidyl-tRNA synthetase
GCU50_RS22125	COG2976	Protein conserved in bacteria
GCU50_RS22175	COG1645	bacterial-type flagellum-dependent swarming motility
GCU50_RS22190	COG1570	exodeoxyribonuclease VII activity
GCU50_RS22195	COG0517	IMP dehydrogenase activity
GCU50_RS22195	COG0516	GMP reductase activity
GCU50_RS22210	COG3077	Addiction module antitoxin, RelB DinJ family
GCU50_RS22225	COG3423	Transcriptional regulator
GCU50_RS22245	COG3668	Plasmid stabilization system
GCU50_RS22270	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
GCU50_RS22275	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
GCU50_RS22290	COG2233	PERMEase
GCU50_RS22300	COG1393	Belongs to the ArsC family
GCU50_RS22305	COG4783	chaperone-mediated protein folding
GCU50_RS22310	COG0628	permease
GCU50_RS22315	COG2116	formate transmembrane transporter activity
GCU50_RS22320	COG3604	Transcriptional regulator
GCU50_RS22330	COG3260	NADH ubiquinone oxidoreductase 20
GCU50_RS22335	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GCU50_RS22340	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
GCU50_RS22340	COG3261	NADH dehydrogenase
GCU50_RS22345	COG0651	ATP synthesis coupled electron transport
GCU50_RS22350	COG4237	Hydrogenase 4 membrane
GCU50_RS22355	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
GCU50_RS22360	COG0650	Formate hydrogenlyase subunit 4
GCU50_RS22365	COG0651	ATP synthesis coupled electron transport
GCU50_RS22370	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
GCU50_RS22375	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
GCU50_RS22380	COG2716	regulation of RNA biosynthetic process
GCU50_RS22390	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
GCU50_RS22395	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
GCU50_RS22400	COG2321	neutral zinc metallopeptidase
GCU50_RS22410	COG0400	carboxylic ester hydrolase activity
GCU50_RS22425	COG1393	Belongs to the ArsC family
GCU50_RS22440	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GCU50_RS22445	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
GCU50_RS22445	COG0493	'glutamate synthase
GCU50_RS22450	COG0494	nUDIX hydrolase
GCU50_RS22455	COG5342	invasion associated locus B
GCU50_RS22460	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
GCU50_RS22480	COG0860	N-Acetylmuramoyl-L-alanine amidase
GCU50_RS22500	COG2837	iron assimilation
GCU50_RS22510	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
GCU50_RS22515	COG4208	sulfate ABC transporter
GCU50_RS22520	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
GCU50_RS22560	COG3115	cell septum assembly
GCU50_RS22570	COG3530	Putative quorum-sensing-regulated virulence factor
GCU50_RS22575	COG0385	Bile acid
GCU50_RS22580	COG0583	DNA-binding transcription factor activity
GCU50_RS22630	COG0840	transmembrane signaling receptor activity
GCU50_RS22640	COG4166	transmembrane transport
GCU50_RS22650	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GCU50_RS22655	COG4608	Belongs to the ABC transporter superfamily
GCU50_RS22660	COG0444	Belongs to the ABC transporter superfamily
GCU50_RS22665	COG0154	amidase activity
GCU50_RS22685	COG0765	amino acid transport
GCU50_RS22690	COG0765	amino acid transport
GCU50_RS22700	COG3706	GGDEF domain
GCU50_RS22730	COG0583	DNA-binding transcription factor activity
GCU50_RS22750	COG0840	transmembrane signaling receptor activity
GCU50_RS22755	COG0346	lactoylglutathione lyase activity
GCU50_RS22760	COG1113	amino acid transport
GCU50_RS22770	COG0384	phenazine biosynthesis protein PhzF
GCU50_RS22775	COG0477	Major facilitator Superfamily
GCU50_RS22785	COG2315	Protein conserved in bacteria
GCU50_RS22805	COG3415	Transposase
GCU50_RS22810	COG3415	Transposase
GCU50_RS22830	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
GCU50_RS22835	COG1914	H( )-stimulated, divalent metal cation uptake system
GCU50_RS22845	COG0667	Aldo Keto reductase
GCU50_RS22850	COG3961	Belongs to the TPP enzyme family
GCU50_RS22860	COG0837	glucose binding
GCU50_RS22865	COG3279	Response regulator of the LytR AlgR family
GCU50_RS22870	COG3275	phosphorelay sensor kinase activity
GCU50_RS22875	COG0436	Aminotransferase
GCU50_RS22995	COG4974	Belongs to the 'phage' integrase family
GCU50_RS23090	COG0582	viral genome integration into host DNA
GCU50_RS23100	COG2116	formate transmembrane transporter activity
GCU50_RS23110	COG2067	long-chain fatty acid transport protein
GCU50_RS23115	COG3691	Protein conserved in bacteria
GCU50_RS23130	COG2062	phosphohistidine phosphatase, SixA
GCU50_RS23155	COG0730	response to heat
GCU50_RS23160	COG3101	peptidyl-lysine hydroxylation
GCU50_RS23175	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GCU50_RS23180	COG2723	6-phospho-beta-galactosidase activity
GCU50_RS23195	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
GCU50_RS23205	COG0586	Pfam SNARE associated Golgi protein
GCU50_RS23215	COG0285	dihydrofolate synthase activity
GCU50_RS23220	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
GCU50_RS23225	COG1286	toxin biosynthetic process
GCU50_RS23230	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
GCU50_RS23235	COG0163	prenyltransferase activity
GCU50_RS23245	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GCU50_RS23255	COG4160	amino acid transport
GCU50_RS23260	COG4598	ABC transporter
GCU50_RS23265	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GCU50_RS23270	COG1090	epimerase
GCU50_RS23275	COG0625	glutathione transferase activity
GCU50_RS23280	COG0625	glutathione transferase activity
GCU50_RS23285	COG0622	Phosphoesterase
GCU50_RS23295	COG1609	Transcriptional regulator
GCU50_RS23300	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GCU50_RS23310	COG3037	sugar-specific permease SgaT UlaA
GCU50_RS23315	COG3959	Transketolase, thiamine diphosphate binding domain
GCU50_RS23320	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
GCU50_RS23345	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GCU50_RS23350	COG0471	metal ion transport
GCU50_RS23350	COG0490	domain, Protein
GCU50_RS23360	COG0436	Aminotransferase
GCU50_RS23365	COG0583	DNA-binding transcription factor activity
GCU50_RS23405	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
GCU50_RS23415	COG0839	Belongs to the complex I subunit 6 family
GCU50_RS23425	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
GCU50_RS23430	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GCU50_RS23440	COG0784	Response regulator, receiver
GCU50_RS23440	COG0835	chemotaxis
GCU50_RS23450	COG2153	protein acetylation
GCU50_RS23455	COG4575	ribosome binding
GCU50_RS23460	COG1169	isochorismate synthase
GCU50_RS23470	COG0596	Alpha beta hydrolase
GCU50_RS23485	COG0318	PFAM AMP-dependent synthetase and ligase
GCU50_RS23505	COG0247	lactate metabolic process
GCU50_RS23515	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
GCU50_RS23520	COG2271	Major facilitator Superfamily
GCU50_RS23525	COG0584	glycerophosphoryl diester phosphodiesterase
GCU50_RS23530	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
GCU50_RS23540	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GCU50_RS23565	COG0642	Histidine kinase
GCU50_RS23565	COG2198	Histidine kinase
GCU50_RS23580	COG2169	Transcriptional regulator
GCU50_RS23580	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
GCU50_RS23585	COG3145	DNA-N1-methyladenine dioxygenase activity
GCU50_RS23590	COG4615	Cyclic peptide transporter
GCU50_RS23595	COG2239	Acts as a magnesium transporter
GCU50_RS23600	COG0659	secondary active sulfate transmembrane transporter activity
GCU50_RS23635	COG1061	Type III restriction enzyme res subunit
GCU50_RS23645	COG2814	Major facilitator Superfamily
GCU50_RS23655	COG4172	Belongs to the ABC transporter superfamily
GCU50_RS23660	COG4239	(ABC) transporter, permease
GCU50_RS23665	COG4174	ABC transporter (Permease)
GCU50_RS23670	COG4166	transmembrane transport
GCU50_RS23675	COG2200	EAL domain
GCU50_RS23680	COG0791	NLP P60 protein
GCU50_RS23685	COG0671	phosphoesterase, PA-phosphatase related
GCU50_RS23690	COG0523	cobalamin synthesis protein
GCU50_RS23695	COG0246	Mannitol dehydrogenase
GCU50_RS23725	COG1105	Belongs to the carbohydrate kinase PfkB family
GCU50_RS23730	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GCU50_RS23730	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GCU50_RS23730	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
GCU50_RS23740	COG2855	membrane
GCU50_RS23745	COG0583	DNA-binding transcription factor activity
GCU50_RS23750	COG0833	amino acid
GCU50_RS23760	COG0477	Major facilitator Superfamily
GCU50_RS23770	COG2311	Membrane
GCU50_RS23780	COG1879	ABC-type sugar transport system periplasmic component
GCU50_RS23785	COG1129	ABC transporter
GCU50_RS23790	COG4211	Belongs to the binding-protein-dependent transport system permease family
GCU50_RS23805	COG2949	membrane
GCU50_RS23815	COG1346	cytolysis
GCU50_RS23825	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
GCU50_RS23845	COG2723	6-phospho-beta-galactosidase activity
GCU50_RS23860	COG1028	Short-chain dehydrogenase reductase Sdr
GCU50_RS23865	COG0586	Pfam SNARE associated Golgi protein
GCU50_RS23875	COG1686	Belongs to the peptidase S11 family
GCU50_RS23890	COG0277	FAD linked oxidase domain protein
GCU50_RS23895	COG1472	Belongs to the glycosyl hydrolase 3 family
GCU50_RS23900	COG1732	Glycine betaine
GCU50_RS23905	COG1174	glycine betaine transport
GCU50_RS23910	COG1125	glycine betaine transport
GCU50_RS23915	COG1174	glycine betaine transport
GCU50_RS23925	COG0789	Transcriptional regulator
GCU50_RS23930	COG3275	phosphorelay sensor kinase activity
GCU50_RS23940	COG4807	Protein conserved in bacteria
GCU50_RS23945	COG4808	Protein conserved in bacteria
GCU50_RS23950	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GCU50_RS23950	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GCU50_RS23955	COG0489	protein tyrosine kinase activity
GCU50_RS23965	COG5455	response to cobalt ion
GCU50_RS23980	COG2182	Extracellular solute-binding protein
GCU50_RS23985	COG1175	transmembrane transport
GCU50_RS23990	COG3833	ABC-type maltose transport systems, permease component
GCU50_RS23995	COG3867	Arabinogalactan endo-beta-1,4-galactanase
GCU50_RS24000	COG1874	Beta-galactosidase
GCU50_RS24030	COG0840	transmembrane signaling receptor activity
GCU50_RS24060	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
GCU50_RS24065	COG0351	phosphomethylpyrimidine kinase
GCU50_RS24070	COG1830	Aldolase
GCU50_RS24080	COG0826	peptidase U32
GCU50_RS24090	COG0745	RESPONSE REGULATOR receiver
GCU50_RS24095	COG2205	protein histidine kinase activity
GCU50_RS24110	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GCU50_RS24115	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GCU50_RS24120	COG0443	Heat shock 70 kDa protein
GCU50_RS24125	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
GCU50_RS24130	COG3447	MASE1 domain protein
GCU50_RS24130	COG5001	Diguanylate cyclase
GCU50_RS24130	COG5002	protein histidine kinase activity
GCU50_RS24145	COG2982	Protein involved in outer membrane biogenesis
GCU50_RS24150	COG0494	nUDIX hydrolase
GCU50_RS24160	COG1253	flavin adenine dinucleotide binding
GCU50_RS24185	COG0463	Glycosyl transferase, family 2
GCU50_RS24190	COG1045	serine acetyltransferase
GCU50_RS24195	COG0438	transferase activity, transferring glycosyl groups
GCU50_RS24205	COG1216	Glycosyl transferase, family 2
GCU50_RS24210	COG0110	maltose O-acetyltransferase activity
GCU50_RS24215	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
GCU50_RS24220	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GCU50_RS24225	COG1051	belongs to the nudix hydrolase family
GCU50_RS24230	COG0297	glycogen (starch) synthase activity
GCU50_RS24235	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
GCU50_RS24235	COG0662	Cupin 2, conserved barrel domain protein
GCU50_RS24240	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GCU50_RS24245	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
GCU50_RS24250	COG2244	polysaccharide biosynthetic process
GCU50_RS24255	COG2327	Polysaccharide pyruvyl transferase
GCU50_RS24260	COG0438	transferase activity, transferring glycosyl groups
GCU50_RS24295	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
GCU50_RS24325	COG0438	transferase activity, transferring glycosyl groups
GCU50_RS24330	COG0438	transferase activity, transferring glycosyl groups
GCU50_RS24350	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
GCU50_RS24375	COG0107	imidazoleglycerol-phosphate synthase activity
GCU50_RS24385	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
GCU50_RS24400	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
GCU50_RS24420	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GCU50_RS24430	COG0531	amino acid
GCU50_RS24435	COG2925	Exonuclease
GCU50_RS24450	COG1289	transmembrane transporter activity
GCU50_RS24550	COG0640	Transcriptional regulator
GCU50_RS24555	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
GCU50_RS24565	COG1376	ErfK ybiS ycfS ynhG family protein
GCU50_RS24575	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GCU50_RS24585	COG0583	DNA-binding transcription factor activity
GCU50_RS24590	COG0604	alcohol dehydrogenase
GCU50_RS24600	COG2207	Transcriptional regulator
GCU50_RS24615	COG1566	PFAM secretion protein HlyD family protein
GCU50_RS24620	COG4977	sequence-specific DNA binding
GCU50_RS24650	COG1902	pentaerythritol trinitrate reductase activity
GCU50_RS24650	COG0446	pyridine nucleotide-disulphide oxidoreductase
GCU50_RS24665	COG0625	glutathione transferase activity
GCU50_RS24670	COG0583	DNA-binding transcription factor activity
GCU50_RS24675	COG0583	DNA-binding transcription factor activity
GCU50_RS24695	COG2813	Specifically methylates the guanine in position
GCU50_RS24700	COG0583	DNA-binding transcription factor activity
GCU50_RS24725	COG0534	Mate efflux family protein
GCU50_RS24735	COG0840	transmembrane signaling receptor activity
GCU50_RS24755	COG0583	DNA-binding transcription factor activity
GCU50_RS24770	COG3423	Transcriptional regulator
GCU50_RS24790	COG0006	proline dipeptidase activity
GCU50_RS24795	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
GCU50_RS24800	COG0604	alcohol dehydrogenase
GCU50_RS24805	COG1309	transcriptional regulator
GCU50_RS24825	COG1215	transferase activity, transferring glycosyl groups
GCU50_RS24835	COG1984	allophanate hydrolase subunit 2
GCU50_RS24845	COG0439	Biotin carboxylase
GCU50_RS24850	COG0511	ligase activity, forming carbon-carbon bonds
GCU50_RS24870	COG0745	RESPONSE REGULATOR receiver
GCU50_RS24890	COG5002	protein histidine kinase activity
GCU50_RS24895	COG0745	RESPONSE REGULATOR receiver
GCU50_RS24910	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GCU50_RS24920	COG0251	oxidation-reduction process
GCU50_RS24960	COG0477	Major facilitator Superfamily
GCU50_RS24970	COG1028	Short-chain dehydrogenase reductase Sdr
GCU50_RS24990	COG1737	Transcriptional regulator
GCU50_RS25030	COG1418	mRNA catabolic process
GCU50_RS25035	COG3727	T/G mismatch-specific endonuclease activity
GCU50_RS25040	COG0697	spore germination
GCU50_RS25045	COG2354	Protein conserved in bacteria
GCU50_RS25050	COG5475	Uncharacterized small protein (DUF2158)
GCU50_RS25110	COG1580	Controls the rotational direction of flagella during chemotaxis
GCU50_RS25120	COG2882	bacterial-type flagellum organization
GCU50_RS25130	COG1317	bacterial-type flagellum organization
GCU50_RS25145	COG1677	Flagellar hook-basal body complex protein FliE
GCU50_RS25155	COG0425	Belongs to the sulfur carrier protein TusA family
GCU50_RS25160	COG2391	methyltransferase activity