locus-tag	class	description
FGE25_RS00010	COG0592	DNA-directed DNA polymerase activity
FGE25_RS00020	COG0187	DNA topoisomerase II activity
FGE25_RS00025	COG0561	phosphatase activity
FGE25_RS00035	COG0823	Involved in the tonB-independent uptake of proteins
FGE25_RS00040	COG5645	(Lipo)protein
FGE25_RS00050	COG0071	Belongs to the small heat shock protein (HSP20) family
FGE25_RS00065	COG2188	Transcriptional regulator
FGE25_RS00080	COG2149	membrane
FGE25_RS00090	COG0641	radical SAM
FGE25_RS00105	COG2814	Major facilitator Superfamily
FGE25_RS00205	COG4791	protein targeting
FGE25_RS00210	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FGE25_RS00225	COG0028	Belongs to the TPP enzyme family
FGE25_RS00230	COG0440	acetolactate synthase activity
FGE25_RS00255	COG0697	spore germination
FGE25_RS00260	COG4580	involved in the transport of maltose and maltodextrins
FGE25_RS00265	COG1447	Phosphotransferase system cellobiose-specific component IIA
FGE25_RS00270	COG2723	6-phospho-beta-galactosidase activity
FGE25_RS00275	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FGE25_RS00285	COG1609	Transcriptional regulator
FGE25_RS00300	COG0747	negative chemotaxis
FGE25_RS00305	COG0601	transmembrane transport
FGE25_RS00315	COG0444	Belongs to the ABC transporter superfamily
FGE25_RS00320	COG4608	Belongs to the ABC transporter superfamily
FGE25_RS00330	COG1063	alcohol dehydrogenase
FGE25_RS00360	COG2814	Major facilitator Superfamily
FGE25_RS00380	COG3180	Ammonia monooxygenase
FGE25_RS00390	COG1902	pentaerythritol trinitrate reductase activity
FGE25_RS00425	COG2982	Protein involved in outer membrane biogenesis
FGE25_RS00430	COG2233	PERMEase
FGE25_RS00435	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
FGE25_RS00440	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FGE25_RS00445	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FGE25_RS00465	COG2860	membrane
FGE25_RS00470	COG1943	Transposase
FGE25_RS00475	COG1561	YicC-like family, N-terminal region
FGE25_RS00485	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
FGE25_RS00505	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
FGE25_RS00510	COG2003	Belongs to the UPF0758 family
FGE25_RS00515	COG0227	Belongs to the bacterial ribosomal protein bL28 family
FGE25_RS00525	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
FGE25_RS00530	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
FGE25_RS00540	COG1519	Transferase
FGE25_RS00555	COG1216	Glycosyl transferase, family 2
FGE25_RS00575	COG0859	PFAM glycosyl transferase family 9
FGE25_RS00580	COG0859	PFAM glycosyl transferase family 9
FGE25_RS00585	COG0859	PFAM glycosyl transferase family 9
FGE25_RS00595	COG0156	8-amino-7-oxononanoate synthase activity
FGE25_RS00605	COG2861	carbohydrate metabolic process
FGE25_RS00610	COG4942	peptidase
FGE25_RS00615	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
FGE25_RS00620	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FGE25_RS00625	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
FGE25_RS00645	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
FGE25_RS00655	COG2186	Transcriptional regulator
FGE25_RS00670	COG3722	fumarate hydratase activity
FGE25_RS00680	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
FGE25_RS00680	COG2213	PTS system mannitol-specific
FGE25_RS00685	COG0625	glutathione transferase activity
FGE25_RS00695	COG3276	selenocysteine insertion sequence binding
FGE25_RS00700	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
FGE25_RS00705	COG3977	Valine--pyruvate aminotransferase
FGE25_RS00710	COG0366	Alpha amylase catalytic
FGE25_RS00715	COG2992	FlgJ-related protein
FGE25_RS00720	COG2207	Transcriptional regulator
FGE25_RS00720	COG1609	Transcriptional regulator
FGE25_RS00725	COG4214	carbohydrate transport
FGE25_RS00730	COG1129	ABC transporter
FGE25_RS00735	COG4213	ABC transporter substrate-binding protein
FGE25_RS00740	COG2115	Belongs to the xylose isomerase family
FGE25_RS00745	COG1070	Carbohydrate kinase
FGE25_RS00755	COG2169	Transcriptional regulator
FGE25_RS00760	COG3274	enterobacterial common antigen metabolic process
FGE25_RS00780	COG3706	GGDEF domain
FGE25_RS00785	COG1776	CheC inhibitor of MCP methylation
FGE25_RS00790	COG2197	response regulator
FGE25_RS00795	COG0488	(ABC) transporter
FGE25_RS00800	COG2944	sequence-specific DNA binding
FGE25_RS00815	COG2814	Major facilitator Superfamily
FGE25_RS00820	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FGE25_RS00830	COG1609	Transcriptional regulator
FGE25_RS00835	COG0243	molybdopterin cofactor binding
FGE25_RS00840	COG0456	acetyltransferase
FGE25_RS00845	COG2818	Glycosylase
FGE25_RS00850	COG5571	outer membrane autotransporter
FGE25_RS00855	COG2223	nitrite transmembrane transporter activity
FGE25_RS00860	COG1764	response to oxidative stress
FGE25_RS00880	COG0747	negative chemotaxis
FGE25_RS00885	COG0601	transmembrane transport
FGE25_RS00890	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FGE25_RS00895	COG0444	Belongs to the ABC transporter superfamily
FGE25_RS00900	COG4608	Belongs to the ABC transporter superfamily
FGE25_RS00940	COG2194	sulfuric ester hydrolase activity
FGE25_RS00960	COG1192	Involved in chromosome partitioning
FGE25_RS00970	COG1215	transferase activity, transferring glycosyl groups
FGE25_RS00980	COG3118	belongs to the thioredoxin family
FGE25_RS00980	COG0457	Tetratricopeptide repeat
FGE25_RS00985	COG2200	EAL domain
FGE25_RS00985	COG2199	diguanylate cyclase activity
FGE25_RS01000	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FGE25_RS01005	COG2200	EAL domain
FGE25_RS01010	COG2982	Protein involved in outer membrane biogenesis
FGE25_RS01015	COG0477	Major facilitator Superfamily
FGE25_RS01020	COG1295	ribonuclease BN
FGE25_RS01025	COG0583	DNA-binding transcription factor activity
FGE25_RS01030	COG1028	Short-chain dehydrogenase reductase Sdr
FGE25_RS01035	COG3111	PFAM Bacterial OB fold (BOF) protein
FGE25_RS01040	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FGE25_RS01060	COG2957	Belongs to the agmatine deiminase family
FGE25_RS01065	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FGE25_RS01085	COG0588	phosphoglycerate mutase activity
FGE25_RS01095	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FGE25_RS01100	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
FGE25_RS01110	COG0339	signal peptide processing
FGE25_RS01135	COG0306	phosphate transporter
FGE25_RS01140	COG2081	HI0933 family
FGE25_RS01160	COG3501	Rhs element vgr protein
FGE25_RS01220	COG0679	Auxin Efflux Carrier
FGE25_RS01225	COG1028	Short-chain dehydrogenase reductase Sdr
FGE25_RS01245	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FGE25_RS01250	COG0601	transmembrane transport
FGE25_RS01255	COG0747	negative chemotaxis
FGE25_RS01265	COG3479	Phenolic acid decarboxylase
FGE25_RS01305	COG0628	permease
FGE25_RS01310	COG0477	Major facilitator Superfamily
FGE25_RS01320	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
FGE25_RS01335	COG3714	YhhN family
FGE25_RS01345	COG3776	membrane
FGE25_RS01350	COG0742	ribosomal rna small subunit methyltransferase
FGE25_RS01355	COG0552	protein localization to endoplasmic reticulum
FGE25_RS01360	COG2884	Cell division ATP-binding protein ftsE
FGE25_RS01365	COG2177	Part of the ABC transporter FtsEX involved in
FGE25_RS01370	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FGE25_RS01375	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
FGE25_RS01390	COG0683	leucine binding
FGE25_RS01395	COG0559	Belongs to the binding-protein-dependent transport system permease family
FGE25_RS01405	COG0411	ABC transporter
FGE25_RS01410	COG0410	ABC transporter
FGE25_RS01420	COG1653	transport
FGE25_RS01440	COG0584	glycerophosphoryl diester phosphodiesterase
FGE25_RS01450	COG0405	Gamma-glutamyltransferase
FGE25_RS01455	COG1247	-acetyltransferase
FGE25_RS01460	COG0673	inositol 2-dehydrogenase activity
FGE25_RS01465	COG1741	Belongs to the pirin family
FGE25_RS01470	COG1609	Transcriptional regulator
FGE25_RS01475	COG3265	gluconokinase activity
FGE25_RS01480	COG2610	gluconate transmembrane transporter activity
FGE25_RS01485	COG2095	MarC family integral membrane protein
FGE25_RS01490	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
FGE25_RS01515	COG0058	SHG alpha-glucan phosphorylase activity
FGE25_RS01520	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
FGE25_RS01525	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FGE25_RS01535	COG1349	DNA-binding transcription factor activity
FGE25_RS01540	COG2909	trisaccharide binding
FGE25_RS01545	COG0058	SHG alpha-glucan phosphorylase activity
FGE25_RS01550	COG1640	4-alpha-glucanotransferase
FGE25_RS01555	COG2610	gluconate transmembrane transporter activity
FGE25_RS01590	COG1918	ferrous iron import across plasma membrane
FGE25_RS01595	COG2183	response to ionizing radiation
FGE25_RS01600	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FGE25_RS01605	COG0745	RESPONSE REGULATOR receiver
FGE25_RS01615	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
FGE25_RS01625	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
FGE25_RS01630	COG1011	Hydrolase
FGE25_RS01640	COG0494	nUDIX hydrolase
FGE25_RS01645	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
FGE25_RS01650	COG4972	Pilus assembly protein
FGE25_RS01655	COG3166	PFAM Fimbrial assembly family protein
FGE25_RS01670	COG4796	Type ii and iii secretion system protein
FGE25_RS01675	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
FGE25_RS01685	COG3266	domain, Protein
FGE25_RS01690	COG0338	D12 class N6 adenine-specific DNA methyltransferase
FGE25_RS01695	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
FGE25_RS01720	COG2146	nitrite reductase [NAD(P)H] activity
FGE25_RS01725	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FGE25_RS01730	COG0402	S-adenosylhomocysteine deaminase activity
FGE25_RS01755	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FGE25_RS01760	COG1289	transmembrane transporter activity
FGE25_RS01770	COG1765	OsmC-like protein
FGE25_RS01775	COG3954	Phosphoribulokinase
FGE25_RS01780	COG3089	Belongs to the UPF0270 family
FGE25_RS01785	COG0429	hydrolase of the alpha beta-hydrolase fold
FGE25_RS01795	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
FGE25_RS01830	COG0679	Auxin Efflux Carrier
FGE25_RS01840	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
FGE25_RS01850	COG0488	(ABC) transporter
FGE25_RS01855	COG2249	NAD(P)H dehydrogenase (quinone) activity
FGE25_RS01860	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FGE25_RS01860	COG0475	glutathione-regulated potassium exporter activity
FGE25_RS01865	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
FGE25_RS01870	COG1047	Peptidyl-prolyl cis-trans
FGE25_RS01880	COG0545	Peptidyl-prolyl cis-trans isomerase
FGE25_RS01885	COG2964	Protein conserved in bacteria
FGE25_RS01925	COG2906	2 iron, 2 sulfur cluster binding
FGE25_RS01940	COG0051	transcription antitermination factor activity, RNA binding
FGE25_RS01980	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
FGE25_RS02030	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
FGE25_RS02040	COG0200	Binds to the 23S rRNA
FGE25_RS02045	COG0201	protein transport
FGE25_RS02075	COG0203	ribosomal protein L17
FGE25_RS02085	COG0789	Transcriptional regulator
FGE25_RS02100	COG0569	domain protein
FGE25_RS02120	COG0758	DNA mediated transformation
FGE25_RS02130	COG0551	DNA topoisomerase type I activity
FGE25_RS02150	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
FGE25_RS02190	COG1126	abc transporter atp-binding protein
FGE25_RS02195	COG0765	amino acid transport
FGE25_RS02200	COG4597	amino acid ABC transporter
FGE25_RS02205	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FGE25_RS02230	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FGE25_RS02240	COG4145	pantothenate transmembrane transporter activity
FGE25_RS02245	COG3924	membrane
FGE25_RS02250	COG0439	Biotin carboxylase
FGE25_RS02255	COG0511	ligase activity, forming carbon-carbon bonds
FGE25_RS02260	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
FGE25_RS02265	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
FGE25_RS02275	COG2200	EAL domain
FGE25_RS02275	COG2199	diguanylate cyclase activity
FGE25_RS02280	COG1077	Cell shape determining protein MreB Mrl
FGE25_RS02285	COG1792	Involved in formation and maintenance of cell shape
FGE25_RS02290	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
FGE25_RS02300	COG1530	ribonuclease E activity
FGE25_RS02305	COG3164	Protein of unknown function
FGE25_RS02310	COG0312	modulator of DNA gyrase
FGE25_RS02315	COG0583	DNA-binding transcription factor activity
FGE25_RS02330	COG1289	transmembrane transporter activity
FGE25_RS02340	COG2732	(Barnase) inhibitor
FGE25_RS02370	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FGE25_RS02375	COG3105	Protein conserved in bacteria
FGE25_RS02380	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
FGE25_RS02395	COG0625	glutathione transferase activity
FGE25_RS02400	COG2969	positive regulation of protein catabolic process
FGE25_RS02405	COG0493	'glutamate synthase
FGE25_RS02410	COG0069	glutamate synthase activity
FGE25_RS02410	COG0070	glutamate synthase
FGE25_RS02410	COG0067	glutamate synthase
FGE25_RS02415	COG1242	4 iron, 4 sulfur cluster binding
FGE25_RS02420	COG5002	protein histidine kinase activity
FGE25_RS02420	COG2198	Histidine kinase
FGE25_RS02420	COG0784	Response regulator, receiver
FGE25_RS02425	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
FGE25_RS02435	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FGE25_RS02445	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FGE25_RS02450	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
FGE25_RS02460	COG1137	ATPase activity
FGE25_RS02465	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
FGE25_RS02470	COG3117	lipopolysaccharide transmembrane transporter activity
FGE25_RS02475	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
FGE25_RS02485	COG0530	calcium, potassium:sodium antiporter activity
FGE25_RS02490	COG1127	ABC transporter
FGE25_RS02495	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
FGE25_RS02505	COG2854	intermembrane phospholipid transfer
FGE25_RS02510	COG3113	response to antibiotic
FGE25_RS02515	COG5007	Belongs to the BolA IbaG family
FGE25_RS02545	COG0697	spore germination
FGE25_RS02555	COG2027	D-alanyl-D-alanine carboxypeptidase
FGE25_RS02560	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FGE25_RS02565	COG1534	Rna-binding protein
FGE25_RS02575	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FGE25_RS02580	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
FGE25_RS02590	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FGE25_RS02640	COG0137	argininosuccinate synthase activity
FGE25_RS02655	COG0195	Participates in both transcription termination and antitermination
FGE25_RS02695	COG0513	Belongs to the DEAD box helicase family
FGE25_RS02700	COG0814	amino acid
FGE25_RS02705	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FGE25_RS02725	COG3153	acetyltransferase
FGE25_RS02730	COG2827	Endonuclease containing a URI domain
FGE25_RS02735	COG3787	Belongs to the UPF0306 family
FGE25_RS02740	COG0693	protein deglycase activity
FGE25_RS02745	COG0702	epimerase
FGE25_RS02750	COG0701	Predicted permease
FGE25_RS02755	COG2823	Periplasmic or secreted lipoprotein
FGE25_RS02770	COG3107	peptidoglycan biosynthetic process
FGE25_RS02775	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
FGE25_RS02780	COG2721	sulfolactate sulfo-lyase activity
FGE25_RS02785	COG2271	Major facilitator Superfamily
FGE25_RS02795	COG2084	Dehydrogenase
FGE25_RS02800	COG1929	Belongs to the glycerate kinase type-1 family
FGE25_RS02815	COG0519	Catalyzes the synthesis of GMP from XMP
FGE25_RS02825	COG2207	Transcriptional regulator
FGE25_RS02830	COG1741	Belongs to the pirin family
FGE25_RS02835	COG0583	DNA-binding transcription factor activity
FGE25_RS02840	COG3152	Membrane
FGE25_RS02845	COG0435	Glutathione S-transferase
FGE25_RS02850	COG2259	Doxx family
FGE25_RS02860	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
FGE25_RS02865	COG4575	ribosome binding
FGE25_RS02870	COG1422	Protein of unknown function (DUF1090)
FGE25_RS02880	COG0586	Pfam SNARE associated Golgi protein
FGE25_RS02885	COG2186	Transcriptional regulator
FGE25_RS02890	COG2271	Major facilitator Superfamily
FGE25_RS02900	COG2721	sulfolactate sulfo-lyase activity
FGE25_RS02915	COG0861	Integral membrane protein TerC family
FGE25_RS02920	COG0673	inositol 2-dehydrogenase activity
FGE25_RS02925	COG1451	nucleotide metabolic process
FGE25_RS02935	COG1902	pentaerythritol trinitrate reductase activity
FGE25_RS02935	COG0446	pyridine nucleotide-disulphide oxidoreductase
FGE25_RS02940	COG1070	Carbohydrate kinase
FGE25_RS02945	COG1830	Aldolase
FGE25_RS02960	COG0840	transmembrane signaling receptor activity
FGE25_RS02970	COG1695	Transcriptional regulator
FGE25_RS02975	COG2375	cellular response to nickel ion
FGE25_RS02985	COG2204	response regulator
FGE25_RS02995	COG4191	Histidine kinase
FGE25_RS02995	COG0784	Response regulator, receiver
FGE25_RS03025	COG4974	Belongs to the 'phage' integrase family
FGE25_RS03120	COG3663	DNA glycosylase
FGE25_RS03125	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FGE25_RS03130	COG0358	DNA primase activity
FGE25_RS03150	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
FGE25_RS03160	COG0617	tRNA 3'-terminal CCA addition
FGE25_RS03165	COG4991	sh3 domain protein
FGE25_RS03170	COG3025	triphosphatase activity
FGE25_RS03180	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
FGE25_RS03180	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
FGE25_RS03205	COG3384	dioxygenase
FGE25_RS03210	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FGE25_RS03225	COG0754	glutathionylspermidine amidase activity
FGE25_RS03240	COG0494	nUDIX hydrolase
FGE25_RS03245	COG3151	Protein conserved in bacteria
FGE25_RS03250	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
FGE25_RS03255	COG3150	esterase
FGE25_RS03260	COG0187	DNA topoisomerase II activity
FGE25_RS03265	COG2207	Transcriptional regulator
FGE25_RS03265	COG1917	Cupin 2, conserved barrel domain protein
FGE25_RS03275	COG2211	Major facilitator Superfamily
FGE25_RS03280	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
FGE25_RS03285	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
FGE25_RS03290	COG2249	NAD(P)H dehydrogenase (quinone) activity
FGE25_RS03300	COG0745	RESPONSE REGULATOR receiver
FGE25_RS03305	COG3111	PFAM Bacterial OB fold (BOF) protein
FGE25_RS03315	COG0204	Acyl-transferase
FGE25_RS03320	COG2132	Multicopper oxidase
FGE25_RS03325	COG1032	radical SAM domain protein
FGE25_RS03330	COG0656	L-ascorbic acid biosynthetic process
FGE25_RS03335	COG1979	alcohol dehydrogenase
FGE25_RS03340	COG2207	Transcriptional regulator
FGE25_RS03345	COG0586	Pfam SNARE associated Golgi protein
FGE25_RS03350	COG0626	cystathionine gamma-synthase activity
FGE25_RS03355	COG0811	peptide transport
FGE25_RS03360	COG0848	biopolymer transport protein
FGE25_RS03365	COG1028	Short-chain dehydrogenase reductase Sdr
FGE25_RS03385	COG2862	Uncharacterized protein family, UPF0114
FGE25_RS03390	COG0667	Aldo Keto reductase
FGE25_RS03400	COG0840	transmembrane signaling receptor activity
FGE25_RS03410	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
FGE25_RS03415	COG0437	4 iron, 4 sulfur cluster binding
FGE25_RS03420	COG5557	Pfam Polysulphide reductase, NrfD
FGE25_RS03425	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
FGE25_RS03430	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
FGE25_RS03435	COG1773	rubredoxin
FGE25_RS03440	COG0375	protein maturation
FGE25_RS03445	COG0298	carbon dioxide binding
FGE25_RS03450	COG1349	DNA-binding transcription factor activity
FGE25_RS03455	COG5001	Diguanylate cyclase
FGE25_RS03460	COG0625	glutathione transferase activity
FGE25_RS03515	COG3615	Tellurite resistance protein tehB
FGE25_RS03525	COG3615	Tellurite resistance protein tehB
FGE25_RS03550	COG2226	methyltransferase
FGE25_RS03555	COG2890	protein-(glutamine-N5) methyltransferase activity
FGE25_RS03565	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
FGE25_RS03575	COG2977	Belongs to the P-Pant transferase superfamily
FGE25_RS03580	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FGE25_RS03615	COG1811	Na channel or pump
FGE25_RS03620	COG1982	Orn Lys Arg decarboxylase major
FGE25_RS03635	COG3493	citrate carrier protein
FGE25_RS03640	COG0179	Fumarylacetoacetate (FAA) hydrolase
FGE25_RS03650	COG3052	prosthetic group binding
FGE25_RS03670	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
FGE25_RS03680	COG2211	Major facilitator Superfamily
FGE25_RS03695	COG1194	a g-specific adenine glycosylase
FGE25_RS03705	COG3171	Protein conserved in bacteria
FGE25_RS03715	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FGE25_RS03730	COG0762	integral membrane protein
FGE25_RS03735	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
FGE25_RS03740	COG2805	Type II/IV secretion system protein
FGE25_RS03745	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FGE25_RS03770	COG1385	rRNA (uridine-N3-)-methyltransferase activity
FGE25_RS03775	COG2356	endonuclease I
FGE25_RS03780	COG3091	SprT-like family
FGE25_RS03785	COG2814	Major facilitator Superfamily
FGE25_RS03800	COG1166	arginine decarboxylase activity
FGE25_RS03805	COG0501	Belongs to the peptidase M48B family
FGE25_RS03810	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
FGE25_RS03820	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
FGE25_RS03825	COG0126	phosphoglycerate kinase activity
FGE25_RS03830	COG0191	fructose-bisphosphate aldolase activity
FGE25_RS03835	COG0668	transmembrane transport
FGE25_RS03840	COG1279	arginine transmembrane transporter activity
FGE25_RS03845	COG2968	Membrane
FGE25_RS03855	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
FGE25_RS03860	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FGE25_RS03865	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
FGE25_RS03885	COG0006	proline dipeptidase activity
FGE25_RS03890	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FGE25_RS03895	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FGE25_RS03910	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FGE25_RS03910	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FGE25_RS03915	COG1028	Short-chain dehydrogenase reductase Sdr
FGE25_RS03920	COG2723	6-phospho-beta-galactosidase activity
FGE25_RS03925	COG1737	Transcriptional regulator
FGE25_RS03930	COG1272	protein, Hemolysin III
FGE25_RS03950	COG0716	FMN binding
FGE25_RS03955	COG4974	Belongs to the 'phage' integrase family
FGE25_RS03960	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FGE25_RS03975	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
FGE25_RS03980	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
FGE25_RS03985	COG1811	Na channel or pump
FGE25_RS03995	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
FGE25_RS04000	COG0583	DNA-binding transcription factor activity
FGE25_RS04005	COG4942	peptidase
FGE25_RS04040	COG3592	Divergent 4Fe-4S mono-cluster
FGE25_RS04045	COG2388	GCN5-related N-acetyl-transferase
FGE25_RS04060	COG2610	gluconate transmembrane transporter activity
FGE25_RS04065	COG1312	Catalyzes the dehydration of D-mannonate
FGE25_RS04080	COG2226	methyltransferase
FGE25_RS04085	COG2267	carboxylic ester hydrolase activity
FGE25_RS04105	COG2850	peptidyl-arginine hydroxylation
FGE25_RS04130	COG0583	DNA-binding transcription factor activity
FGE25_RS04135	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
FGE25_RS04140	COG1210	Utp--glucose-1-phosphate uridylyltransferase
FGE25_RS04145	COG3300	MHYT domain
FGE25_RS04145	COG5001	Diguanylate cyclase
FGE25_RS04155	COG0457	Tetratricopeptide repeat
FGE25_RS04160	COG1215	transferase activity, transferring glycosyl groups
FGE25_RS04165	COG1215	transferase activity, transferring glycosyl groups
FGE25_RS04175	COG2200	EAL domain
FGE25_RS04175	COG2202	Pas domain
FGE25_RS04175	COG2199	diguanylate cyclase activity
FGE25_RS04180	COG0745	RESPONSE REGULATOR receiver
FGE25_RS04180	COG3706	GGDEF domain
FGE25_RS04185	COG0626	cystathionine gamma-synthase activity
FGE25_RS04200	COG2011	ABC-type metal ion transport system permease component
FGE25_RS04205	COG1464	Belongs to the NlpA lipoprotein family
FGE25_RS04210	COG0183	Belongs to the thiolase family
FGE25_RS04215	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
FGE25_RS04220	COG0823	Involved in the tonB-independent uptake of proteins
FGE25_RS04230	COG1028	Short-chain dehydrogenase reductase Sdr
FGE25_RS04235	COG2814	Major facilitator Superfamily
FGE25_RS04240	COG0823	Involved in the tonB-independent uptake of proteins
FGE25_RS04250	COG3842	ATPase activity
FGE25_RS04255	COG0395	ABC-type sugar transport system, permease component
FGE25_RS04260	COG1175	transmembrane transport
FGE25_RS04270	COG1794	racemase activity, acting on amino acids and derivatives
FGE25_RS04275	COG0583	DNA-binding transcription factor activity
FGE25_RS04280	COG0019	diaminopimelate decarboxylase activity
FGE25_RS04285	COG1609	Transcriptional regulator
FGE25_RS04290	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FGE25_RS04295	COG2723	6-phospho-beta-galactosidase activity
FGE25_RS04305	COG2186	Transcriptional regulator
FGE25_RS04315	COG1609	Transcriptional regulator
FGE25_RS04325	COG0477	Major facilitator Superfamily
FGE25_RS04330	COG0667	Aldo Keto reductase
FGE25_RS04340	COG0861	Integral membrane protein TerC family
FGE25_RS04350	COG0494	nUDIX hydrolase
FGE25_RS04365	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
FGE25_RS04370	COG2165	general secretion pathway protein
FGE25_RS04375	COG4795	General secretion pathway protein
FGE25_RS04385	COG4967	type IV pilus modification protein PilV
FGE25_RS04390	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
FGE25_RS04400	COG1074	ATP-dependent DNA helicase activity
FGE25_RS04405	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FGE25_RS04410	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
FGE25_RS04410	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
FGE25_RS04415	COG0860	N-Acetylmuramoyl-L-alanine amidase
FGE25_RS04430	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
FGE25_RS04435	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
FGE25_RS04440	COG2166	iron-sulfur cluster assembly
FGE25_RS04445	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
FGE25_RS04455	COG0583	DNA-binding transcription factor activity
FGE25_RS04460	COG2363	Small membrane protein
FGE25_RS04470	COG2234	aminopeptidase activity
FGE25_RS04500	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
FGE25_RS04510	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
FGE25_RS04530	COG4942	peptidase
FGE25_RS04530	COG1388	LysM domain
FGE25_RS04545	COG0477	Major facilitator Superfamily
FGE25_RS04570	COG2207	Transcriptional regulator
FGE25_RS04580	COG4221	oxidoreductase activity
FGE25_RS04585	COG1902	pentaerythritol trinitrate reductase activity
FGE25_RS04590	COG0583	DNA-binding transcription factor activity
FGE25_RS04600	COG2207	Transcriptional regulator
FGE25_RS04620	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
FGE25_RS04625	COG4221	oxidoreductase activity
FGE25_RS04645	COG1486	melibiose metabolic process
FGE25_RS04650	COG1917	Cupin 2, conserved barrel domain protein
FGE25_RS04650	COG2169	Transcriptional regulator
FGE25_RS04655	COG1447	Phosphotransferase system cellobiose-specific component IIA
FGE25_RS04660	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FGE25_RS04665	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FGE25_RS04685	COG5002	protein histidine kinase activity
FGE25_RS04695	COG2353	YceI-like domain
FGE25_RS04720	COG2249	NAD(P)H dehydrogenase (quinone) activity
FGE25_RS04730	COG3707	response regulator
FGE25_RS04735	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FGE25_RS04745	COG1116	anion transmembrane transporter activity
FGE25_RS04750	COG2146	nitrite reductase [NAD(P)H] activity
FGE25_RS04750	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FGE25_RS04755	COG0243	molybdopterin cofactor binding
FGE25_RS04760	COG0745	RESPONSE REGULATOR receiver
FGE25_RS04765	COG2205	protein histidine kinase activity
FGE25_RS04775	COG0596	Alpha beta hydrolase
FGE25_RS04800	COG3604	Transcriptional regulator
FGE25_RS04805	COG0309	Hydrogenase expression formation protein (HypE)
FGE25_RS04810	COG0409	Hydrogenase expression formation protein
FGE25_RS04815	COG0298	carbon dioxide binding
FGE25_RS04820	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
FGE25_RS04825	COG0375	protein maturation
FGE25_RS04835	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
FGE25_RS04840	COG0651	ATP synthesis coupled electron transport
FGE25_RS04845	COG0650	Formate hydrogenlyase subunit 4
FGE25_RS04850	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
FGE25_RS04850	COG3261	NADH dehydrogenase
FGE25_RS04855	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FGE25_RS04860	COG3260	NADH ubiquinone oxidoreductase 20
FGE25_RS04870	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
FGE25_RS04875	COG3706	GGDEF domain
FGE25_RS04880	COG0583	DNA-binding transcription factor activity
FGE25_RS04885	COG0667	Aldo Keto reductase
FGE25_RS04890	COG1609	Transcriptional regulator
FGE25_RS04895	COG2190	(PTS) system
FGE25_RS04895	COG1263	PTS System
FGE25_RS04895	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FGE25_RS04910	COG0640	Transcriptional regulator
FGE25_RS04920	COG1396	sequence-specific DNA binding
FGE25_RS04930	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FGE25_RS04930	COG2169	Transcriptional regulator
FGE25_RS04935	COG3387	PFAM Glycoside hydrolase 15-related
FGE25_RS04940	COG1028	Short-chain dehydrogenase reductase Sdr
FGE25_RS04945	COG2723	6-phospho-beta-galactosidase activity
FGE25_RS04950	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FGE25_RS04950	COG1263	PTS System
FGE25_RS04955	COG1609	Transcriptional regulator
FGE25_RS04960	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
FGE25_RS04965	COG3383	formate dehydrogenase (NAD+) activity
FGE25_RS04970	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
FGE25_RS04980	COG1773	rubredoxin
FGE25_RS04980	COG0426	domain, Protein
FGE25_RS04990	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
FGE25_RS04990	COG0517	IMP dehydrogenase activity
FGE25_RS04995	COG1349	DNA-binding transcription factor activity
FGE25_RS05000	COG4578	phosphoenolpyruvate-dependent sugar phosphotransferase system
FGE25_RS05005	COG1028	Short-chain dehydrogenase reductase Sdr
FGE25_RS05015	COG3732	PTS system glucitol sorbitol-specific
FGE25_RS05020	COG3730	PTS system glucitol sorbitol-specific
FGE25_RS05025	COG2951	lytic endotransglycosylase activity
FGE25_RS05035	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FGE25_RS05040	COG0803	Belongs to the bacterial solute-binding protein 9 family
FGE25_RS05045	COG1546	Belongs to the CinA family
FGE25_RS05095	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FGE25_RS05100	COG1238	metal cluster binding
FGE25_RS05105	COG2918	glutathione biosynthetic process
FGE25_RS05120	COG0545	Peptidyl-prolyl cis-trans isomerase
FGE25_RS05125	COG2814	Major facilitator Superfamily
FGE25_RS05130	COG1566	PFAM secretion protein HlyD family protein
FGE25_RS05135	COG1846	Transcriptional regulator
FGE25_RS05145	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
FGE25_RS05150	COG2814	Major facilitator Superfamily
FGE25_RS05160	COG4176	ABC-type proline glycine betaine transport system permease component
FGE25_RS05185	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
FGE25_RS05190	COG4575	ribosome binding
FGE25_RS05210	COG0401	homolog of Blt101
FGE25_RS05230	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
FGE25_RS05235	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FGE25_RS05240	COG0640	Transcriptional regulator
FGE25_RS05275	COG0076	glutamate decarboxylase activity
FGE25_RS05280	COG0531	amino acid
FGE25_RS05290	COG3639	organic phosphonate transmembrane transporter activity
FGE25_RS05300	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
FGE25_RS05310	COG3501	Rhs element vgr protein
FGE25_RS05330	COG1175	transmembrane transport
FGE25_RS05335	COG3842	ATPase activity
FGE25_RS05350	COG4232	protein-disulfide reductase activity
FGE25_RS05360	COG4533	DNA binding
FGE25_RS05380	COG1815	bacterial-type flagellum-dependent cell motility
FGE25_RS05385	COG1558	bacterial-type flagellum-dependent cell motility
FGE25_RS05390	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
FGE25_RS05395	COG1749	Flagellar hook protein flgE
FGE25_RS05405	COG4786	Flagellar basal body rod
FGE25_RS05425	COG1256	bacterial-type flagellum assembly
FGE25_RS05430	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FGE25_RS05435	COG0840	transmembrane signaling receptor activity
FGE25_RS05440	COG1191	sigma factor activity
FGE25_RS05460	COG1360	Flagellar Motor Protein
FGE25_RS05465	COG2198	Histidine kinase
FGE25_RS05465	COG0643	Histidine kinase
FGE25_RS05535	COG3409	Peptidoglycan-binding domain 1 protein
FGE25_RS05535	COG3429	Glucose-6-phosphate dehydrogenase subunit
FGE25_RS05555	COG1475	DNA binding
FGE25_RS05565	COG0582	viral genome integration into host DNA
FGE25_RS05580	COG2867	negative regulation of translational initiation
FGE25_RS05585	COG2914	Belongs to the UPF0125 (RnfH) family
FGE25_RS05605	COG4536	flavin adenine dinucleotide binding
FGE25_RS05610	COG4137	Cytochrome C assembly protein
FGE25_RS05615	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
FGE25_RS05765	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
FGE25_RS05795	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
FGE25_RS05800	COG0287	Prephenate dehydrogenase
FGE25_RS05800	COG1605	Chorismate mutase
FGE25_RS05810	COG0077	Prephenate dehydratase
FGE25_RS05810	COG1605	Chorismate mutase
FGE25_RS05815	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
FGE25_RS05820	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FGE25_RS05825	COG0564	pseudouridine synthase activity
FGE25_RS05835	COG0542	response to heat
FGE25_RS05860	COG0477	Major facilitator Superfamily
FGE25_RS05865	COG5544	Lipoprotein
FGE25_RS05870	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FGE25_RS05875	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FGE25_RS05875	COG1042	CoA-binding domain protein
FGE25_RS05875	COG0045	succinate-CoA ligase (ADP-forming) activity
FGE25_RS05885	COG3118	belongs to the thioredoxin family
FGE25_RS05890	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FGE25_RS05905	COG0513	Belongs to the DEAD box helicase family
FGE25_RS05915	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
FGE25_RS05925	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
FGE25_RS05935	COG3086	response to oxidative stress
FGE25_RS05945	COG0681	Belongs to the peptidase S26 family
FGE25_RS05950	COG0571	ribonuclease III activity
FGE25_RS05960	COG1381	Involved in DNA repair and RecF pathway recombination
FGE25_RS05965	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
FGE25_RS05975	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
FGE25_RS05980	COG3240	lipase activity
FGE25_RS05985	COG1737	Transcriptional regulator
FGE25_RS05995	COG0560	Phosphoserine phosphatase
FGE25_RS06000	COG0590	tRNA wobble adenosine to inosine editing
FGE25_RS06005	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
FGE25_RS06010	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FGE25_RS06010	COG0047	phosphoribosylformylglycinamidine synthase activity
FGE25_RS06015	COG2205	protein histidine kinase activity
FGE25_RS06020	COG3170	Tfp pilus assembly protein FimV
FGE25_RS06025	COG2204	response regulator
FGE25_RS06030	COG0347	Belongs to the P(II) protein family
FGE25_RS06055	COG2814	Major facilitator Superfamily
FGE25_RS06060	COG3711	transcriptional antiterminator
FGE25_RS06065	COG3683	transport system, periplasmic component
FGE25_RS06070	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
FGE25_RS06095	COG0822	iron-sulfur transferase activity
FGE25_RS06115	COG0633	Ferredoxin
FGE25_RS06120	COG2975	iron-sulfur cluster assembly
FGE25_RS06125	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
FGE25_RS06140	COG1737	Transcriptional regulator
FGE25_RS06145	COG2897	thiosulfate sulfurtransferase activity
FGE25_RS06155	COG2190	(PTS) system
FGE25_RS06155	COG1263	PTS System
FGE25_RS06155	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FGE25_RS06160	COG2373	Large extracellular alpha-helical protein
FGE25_RS06165	COG4953	penicillin-binding protein 1C
FGE25_RS06190	COG0124	histidyl-tRNA synthetase
FGE25_RS06195	COG2976	Protein conserved in bacteria
FGE25_RS06215	COG1645	bacterial-type flagellum-dependent swarming motility
FGE25_RS06230	COG1570	exodeoxyribonuclease VII activity
FGE25_RS06235	COG0516	GMP reductase activity
FGE25_RS06235	COG0517	IMP dehydrogenase activity
FGE25_RS06245	COG0582	viral genome integration into host DNA
FGE25_RS06280	COG3846	protein secretion by the type IV secretion system
FGE25_RS06285	COG3093	addiction module antidote protein HigA
FGE25_RS06300	COG0464	growth
FGE25_RS06310	COG0840	transmembrane signaling receptor activity
FGE25_RS06335	COG2200	EAL domain
FGE25_RS06340	COG0248	Ppx GppA phosphatase
FGE25_RS06345	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
FGE25_RS06350	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
FGE25_RS06365	COG2233	PERMEase
FGE25_RS06375	COG1393	Belongs to the ArsC family
FGE25_RS06380	COG4783	chaperone-mediated protein folding
FGE25_RS06385	COG0628	permease
FGE25_RS06390	COG2116	formate transmembrane transporter activity
FGE25_RS06395	COG3604	Transcriptional regulator
FGE25_RS06405	COG3260	NADH ubiquinone oxidoreductase 20
FGE25_RS06410	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FGE25_RS06415	COG3261	NADH dehydrogenase
FGE25_RS06415	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
FGE25_RS06420	COG0651	ATP synthesis coupled electron transport
FGE25_RS06425	COG4237	Hydrogenase 4 membrane
FGE25_RS06430	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FGE25_RS06435	COG0650	Formate hydrogenlyase subunit 4
FGE25_RS06440	COG0651	ATP synthesis coupled electron transport
FGE25_RS06445	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
FGE25_RS06450	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
FGE25_RS06455	COG2716	regulation of RNA biosynthetic process
FGE25_RS06465	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
FGE25_RS06470	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
FGE25_RS06475	COG2321	neutral zinc metallopeptidase
FGE25_RS06485	COG0400	carboxylic ester hydrolase activity
FGE25_RS06500	COG1393	Belongs to the ArsC family
FGE25_RS06515	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FGE25_RS06520	COG3850	Histidine kinase
FGE25_RS06525	COG0493	'glutamate synthase
FGE25_RS06525	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
FGE25_RS06530	COG0494	nUDIX hydrolase
FGE25_RS06535	COG5342	invasion associated locus B
FGE25_RS06545	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
FGE25_RS06565	COG0860	N-Acetylmuramoyl-L-alanine amidase
FGE25_RS06585	COG2837	iron assimilation
FGE25_RS06595	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
FGE25_RS06600	COG4208	sulfate ABC transporter
FGE25_RS06605	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
FGE25_RS06620	COG2190	(PTS) system
FGE25_RS06635	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FGE25_RS06645	COG3115	cell septum assembly
FGE25_RS06655	COG3530	Putative quorum-sensing-regulated virulence factor
FGE25_RS06660	COG0385	Bile acid
FGE25_RS06665	COG0583	DNA-binding transcription factor activity
FGE25_RS06715	COG0840	transmembrane signaling receptor activity
FGE25_RS06740	COG4215	(ABC) transporter
FGE25_RS06800	COG2026	Addiction module toxin, RelE StbE family
FGE25_RS06805	COG3077	Addiction module antitoxin, RelB DinJ family
FGE25_RS06810	COG0174	glutamine synthetase
FGE25_RS06825	COG0840	transmembrane signaling receptor activity
FGE25_RS06835	COG1349	DNA-binding transcription factor activity
FGE25_RS06840	COG1113	amino acid transport
FGE25_RS06855	COG0384	phenazine biosynthesis protein PhzF
FGE25_RS06870	COG2315	Protein conserved in bacteria
FGE25_RS06875	COG1309	transcriptional regulator
FGE25_RS06890	COG3415	Transposase
FGE25_RS06895	COG3415	Transposase
FGE25_RS06910	COG2200	EAL domain
FGE25_RS06910	COG2199	diguanylate cyclase activity
FGE25_RS06915	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FGE25_RS06920	COG1914	H( )-stimulated, divalent metal cation uptake system
FGE25_RS06930	COG0667	Aldo Keto reductase
FGE25_RS06935	COG3961	Belongs to the TPP enzyme family
FGE25_RS06940	COG0038	chloride channel
FGE25_RS06950	COG3279	Response regulator of the LytR AlgR family
FGE25_RS06955	COG3275	phosphorelay sensor kinase activity
FGE25_RS06960	COG0436	Aminotransferase
FGE25_RS06995	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
FGE25_RS07005	COG1174	glycine betaine transport
FGE25_RS07020	COG2986	histidine ammonia-lyase
FGE25_RS07030	COG2188	Transcriptional regulator
FGE25_RS07035	COG0402	S-adenosylhomocysteine deaminase activity
FGE25_RS07045	COG2116	formate transmembrane transporter activity
FGE25_RS07055	COG2067	long-chain fatty acid transport protein
FGE25_RS07060	COG3691	Protein conserved in bacteria
FGE25_RS07075	COG2062	phosphohistidine phosphatase, SixA
FGE25_RS07085	COG2890	protein-(glutamine-N5) methyltransferase activity
FGE25_RS07100	COG0730	response to heat
FGE25_RS07105	COG3101	peptidyl-lysine hydroxylation
FGE25_RS07120	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FGE25_RS07130	COG2723	6-phospho-beta-galactosidase activity
FGE25_RS07140	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FGE25_RS07145	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
FGE25_RS07155	COG0586	Pfam SNARE associated Golgi protein
FGE25_RS07165	COG0285	dihydrofolate synthase activity
FGE25_RS07170	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
FGE25_RS07175	COG1286	toxin biosynthetic process
FGE25_RS07180	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
FGE25_RS07185	COG0163	prenyltransferase activity
FGE25_RS07195	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FGE25_RS07200	COG4215	(ABC) transporter
FGE25_RS07205	COG4160	amino acid transport
FGE25_RS07210	COG4598	ABC transporter
FGE25_RS07225	COG1090	epimerase
FGE25_RS07230	COG0625	glutathione transferase activity
FGE25_RS07235	COG0625	glutathione transferase activity
FGE25_RS07240	COG0622	Phosphoesterase
FGE25_RS07245	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
FGE25_RS07250	COG1609	Transcriptional regulator
FGE25_RS07255	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FGE25_RS07265	COG3037	sugar-specific permease SgaT UlaA
FGE25_RS07270	COG3959	Transketolase, thiamine diphosphate binding domain
FGE25_RS07275	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
FGE25_RS07285	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
FGE25_RS07300	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FGE25_RS07305	COG0471	metal ion transport
FGE25_RS07305	COG0490	domain, Protein
FGE25_RS07315	COG0436	Aminotransferase
FGE25_RS07320	COG0583	DNA-binding transcription factor activity
FGE25_RS07340	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
FGE25_RS07350	COG1034	ATP synthesis coupled electron transport
FGE25_RS07355	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
FGE25_RS07360	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FGE25_RS07365	COG0839	Belongs to the complex I subunit 6 family
FGE25_RS07375	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FGE25_RS07380	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FGE25_RS07390	COG0784	Response regulator, receiver
FGE25_RS07390	COG0835	chemotaxis
FGE25_RS07400	COG2153	protein acetylation
FGE25_RS07405	COG4575	ribosome binding
FGE25_RS07410	COG1169	isochorismate synthase
FGE25_RS07420	COG0596	Alpha beta hydrolase
FGE25_RS07455	COG0247	lactate metabolic process
FGE25_RS07465	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
FGE25_RS07470	COG2271	Major facilitator Superfamily
FGE25_RS07475	COG0584	glycerophosphoryl diester phosphodiesterase
FGE25_RS07480	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FGE25_RS07485	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FGE25_RS07495	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FGE25_RS07505	COG0784	Response regulator, receiver
FGE25_RS07505	COG2205	protein histidine kinase activity
FGE25_RS07515	COG2198	Histidine kinase
FGE25_RS07515	COG0642	Histidine kinase
FGE25_RS07520	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
FGE25_RS07530	COG2169	Transcriptional regulator
FGE25_RS07530	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FGE25_RS07535	COG3145	DNA-N1-methyladenine dioxygenase activity
FGE25_RS07540	COG4615	Cyclic peptide transporter
FGE25_RS07545	COG2239	Acts as a magnesium transporter
FGE25_RS07550	COG0659	secondary active sulfate transmembrane transporter activity
FGE25_RS07570	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FGE25_RS07575	COG0577	efflux transmembrane transporter activity
FGE25_RS07575	COG1136	(ABC) transporter
FGE25_RS07585	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FGE25_RS07595	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FGE25_RS07600	COG1028	Short-chain dehydrogenase reductase Sdr
FGE25_RS07625	COG3082	Protein of unknown function (DUF1414)
FGE25_RS07640	COG1061	Type III restriction enzyme res subunit
FGE25_RS07645	COG1187	pseudouridine synthase activity
FGE25_RS07650	COG2814	Major facilitator Superfamily
FGE25_RS07660	COG4172	Belongs to the ABC transporter superfamily
FGE25_RS07665	COG4239	(ABC) transporter, permease
FGE25_RS07670	COG4174	ABC transporter (Permease)
FGE25_RS07675	COG4166	transmembrane transport
FGE25_RS07680	COG2200	EAL domain
FGE25_RS07685	COG0791	NLP P60 protein
FGE25_RS07690	COG0671	phosphoesterase, PA-phosphatase related
FGE25_RS07695	COG0523	cobalamin synthesis protein
FGE25_RS07700	COG0246	Mannitol dehydrogenase
FGE25_RS07720	COG2814	Major facilitator Superfamily
FGE25_RS07730	COG1105	Belongs to the carbohydrate kinase PfkB family
FGE25_RS07735	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
FGE25_RS07735	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FGE25_RS07735	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FGE25_RS07745	COG2855	membrane
FGE25_RS07750	COG0583	DNA-binding transcription factor activity
FGE25_RS07765	COG0765	amino acid transport
FGE25_RS07775	COG0833	amino acid
FGE25_RS07780	COG4771	TonB-dependent receptor
FGE25_RS07790	COG0477	Major facilitator Superfamily
FGE25_RS07800	COG2311	Membrane
FGE25_RS07810	COG1879	ABC-type sugar transport system periplasmic component
FGE25_RS07815	COG1129	ABC transporter
FGE25_RS07835	COG2949	membrane
FGE25_RS07840	COG0295	cytidine deaminase activity
FGE25_RS07845	COG1346	cytolysis
FGE25_RS07855	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FGE25_RS07875	COG1028	Short-chain dehydrogenase reductase Sdr
FGE25_RS07880	COG0586	Pfam SNARE associated Golgi protein
FGE25_RS07890	COG1686	Belongs to the peptidase S11 family
FGE25_RS07900	COG0277	FAD linked oxidase domain protein
FGE25_RS07905	COG1472	Belongs to the glycosyl hydrolase 3 family
FGE25_RS07910	COG1732	Glycine betaine
FGE25_RS07915	COG1174	glycine betaine transport
FGE25_RS07920	COG1125	glycine betaine transport
FGE25_RS07925	COG1174	glycine betaine transport
FGE25_RS07935	COG0789	Transcriptional regulator
FGE25_RS07940	COG3275	phosphorelay sensor kinase activity
FGE25_RS07950	COG4807	Protein conserved in bacteria
FGE25_RS07955	COG4808	Protein conserved in bacteria
FGE25_RS07965	COG0489	protein tyrosine kinase activity
FGE25_RS07975	COG5455	response to cobalt ion
FGE25_RS07980	COG0604	alcohol dehydrogenase
FGE25_RS07990	COG2182	Extracellular solute-binding protein
FGE25_RS07995	COG1175	transmembrane transport
FGE25_RS08000	COG3833	ABC-type maltose transport systems, permease component
FGE25_RS08005	COG3867	Arabinogalactan endo-beta-1,4-galactanase
FGE25_RS08010	COG1874	Beta-galactosidase
FGE25_RS08035	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
FGE25_RS08040	COG0351	phosphomethylpyrimidine kinase
FGE25_RS08045	COG1830	Aldolase
FGE25_RS08050	COG4948	Mandelate Racemase Muconate Lactonizing
FGE25_RS08075	COG0745	RESPONSE REGULATOR receiver
FGE25_RS08080	COG2205	protein histidine kinase activity
FGE25_RS08095	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FGE25_RS08105	COG0443	Heat shock 70 kDa protein
FGE25_RS08110	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
FGE25_RS08115	COG3447	MASE1 domain protein
FGE25_RS08115	COG5002	protein histidine kinase activity
FGE25_RS08115	COG5001	Diguanylate cyclase
FGE25_RS08130	COG2982	Protein involved in outer membrane biogenesis
FGE25_RS08135	COG0494	nUDIX hydrolase
FGE25_RS08140	COG1349	DNA-binding transcription factor activity
FGE25_RS08145	COG1253	flavin adenine dinucleotide binding
FGE25_RS08165	COG0463	Glycosyl transferase, family 2
FGE25_RS08170	COG1045	serine acetyltransferase
FGE25_RS08175	COG0438	transferase activity, transferring glycosyl groups
FGE25_RS08185	COG1216	Glycosyl transferase, family 2
FGE25_RS08190	COG0110	maltose O-acetyltransferase activity
FGE25_RS08195	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
FGE25_RS08200	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FGE25_RS08205	COG1051	belongs to the nudix hydrolase family
FGE25_RS08210	COG0297	glycogen (starch) synthase activity
FGE25_RS08215	COG0662	Cupin 2, conserved barrel domain protein
FGE25_RS08215	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
FGE25_RS08220	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FGE25_RS08225	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FGE25_RS08230	COG2244	polysaccharide biosynthetic process
FGE25_RS08235	COG2327	Polysaccharide pyruvyl transferase
FGE25_RS08240	COG0438	transferase activity, transferring glycosyl groups
FGE25_RS08250	COG1210	Utp--glucose-1-phosphate uridylyltransferase
FGE25_RS08305	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
FGE25_RS08330	COG0140	phosphoribosyl-ATP diphosphatase activity
FGE25_RS08330	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
FGE25_RS08345	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
FGE25_RS08350	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
FGE25_RS08350	COG0131	Imidazoleglycerol-phosphate dehydratase
FGE25_RS08375	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FGE25_RS08380	COG0531	amino acid
FGE25_RS08385	COG2391	methyltransferase activity
FGE25_RS08390	COG0425	Belongs to the sulfur carrier protein TusA family
FGE25_RS08395	COG2925	Exonuclease
FGE25_RS08410	COG1289	transmembrane transporter activity
FGE25_RS08415	COG2926	Belongs to the UPF0265 family
FGE25_RS08445	COG2241	protein methyltransferase activity
FGE25_RS08455	COG2875	Belongs to the precorrin methyltransferase family
FGE25_RS08505	COG0640	Transcriptional regulator
FGE25_RS08510	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
FGE25_RS08525	COG1376	ErfK ybiS ycfS ynhG family protein
FGE25_RS08530	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FGE25_RS08540	COG3122	Protein conserved in bacteria
FGE25_RS08585	COG0534	Mate efflux family protein
FGE25_RS08595	COG0006	proline dipeptidase activity
FGE25_RS08600	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
FGE25_RS08605	COG0604	alcohol dehydrogenase
FGE25_RS08610	COG1309	transcriptional regulator
FGE25_RS08625	COG0583	DNA-binding transcription factor activity
FGE25_RS08645	COG0583	DNA-binding transcription factor activity
FGE25_RS08650	COG0477	Major facilitator Superfamily
FGE25_RS08655	COG1605	Chorismate mutase
FGE25_RS08665	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FGE25_RS08670	COG1733	regulation of RNA biosynthetic process
FGE25_RS08690	COG3228	Belongs to the MtfA family
FGE25_RS08705	COG1418	mRNA catabolic process
FGE25_RS08710	COG3727	T/G mismatch-specific endonuclease activity
FGE25_RS08715	COG0697	spore germination
FGE25_RS08720	COG2354	Protein conserved in bacteria
FGE25_RS08725	COG5475	Uncharacterized small protein (DUF2158)
FGE25_RS08760	COG1987	bacterial-type flagellum assembly
FGE25_RS08770	COG3190	flagellar
FGE25_RS08795	COG2882	bacterial-type flagellum organization
FGE25_RS08805	COG1317	bacterial-type flagellum organization
FGE25_RS08810	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FGE25_RS08820	COG1677	Flagellar hook-basal body complex protein FliE
FGE25_RS08825	COG0346	lactoylglutathione lyase activity
FGE25_RS08830	COG3706	GGDEF domain
FGE25_RS08840	COG0425	Belongs to the sulfur carrier protein TusA family
FGE25_RS08845	COG2391	methyltransferase activity
FGE25_RS08855	COG0366	Alpha amylase catalytic
FGE25_RS08870	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
FGE25_RS08890	COG1216	Glycosyl transferase, family 2
FGE25_RS08890	COG0438	transferase activity, transferring glycosyl groups
FGE25_RS08905	COG1181	Belongs to the D-alanine--D-alanine ligase family
FGE25_RS08910	COG0673	inositol 2-dehydrogenase activity
FGE25_RS08920	COG1191	sigma factor activity
FGE25_RS08950	COG2197	response regulator
FGE25_RS08960	COG2197	response regulator
FGE25_RS08990	COG0814	amino acid
FGE25_RS09005	COG1528	Iron-storage protein
FGE25_RS09020	COG2814	Major facilitator Superfamily
FGE25_RS09040	COG1879	ABC-type sugar transport system periplasmic component
FGE25_RS09050	COG1172	Belongs to the binding-protein-dependent transport system permease family
FGE25_RS09060	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
FGE25_RS09130	COG0840	transmembrane signaling receptor activity
FGE25_RS09145	COG0745	RESPONSE REGULATOR receiver
FGE25_RS09160	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FGE25_RS09175	COG2211	Major facilitator Superfamily
FGE25_RS09180	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
FGE25_RS09190	COG3102	Protein conserved in bacteria
FGE25_RS09195	COG3142	Participates in the control of copper homeostasis
FGE25_RS09210	COG3788	relative of glutathione S-transferase, MAPEG superfamily
FGE25_RS09215	COG1801	Protein of unknown function DUF72
FGE25_RS09220	COG1335	isochorismatase
FGE25_RS09230	COG0494	nUDIX hydrolase
FGE25_RS09265	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FGE25_RS09275	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
FGE25_RS09280	COG0739	heme binding
FGE25_RS09285	COG1560	Kdo2-lipid A biosynthetic process
FGE25_RS09290	COG0469	pyruvate kinase activity
FGE25_RS09295	COG1737	Transcriptional regulator
FGE25_RS09300	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
FGE25_RS09305	COG0129	dihydroxy-acid dehydratase activity
FGE25_RS09310	COG0800	Aldolase
FGE25_RS09320	COG3141	response to X-ray
FGE25_RS09330	COG2979	Protein of unknown function (DUF533)
FGE25_RS09335	COG1770	oligopeptidase
FGE25_RS09340	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FGE25_RS09350	COG2372	response to copper ion
FGE25_RS09355	COG1276	copper resistance
FGE25_RS09365	COG2990	Protein conserved in bacteria
FGE25_RS09390	COG3008	intermembrane lipid transfer
FGE25_RS09395	COG2995	paraquat-inducible protein a
FGE25_RS09400	COG1956	GAF domain-containing protein
FGE25_RS09420	COG2814	Major facilitator Superfamily
FGE25_RS09425	COG1414	Transcriptional regulator
FGE25_RS09455	COG1278	Cold shock
FGE25_RS09460	COG2226	methyltransferase
FGE25_RS09475	COG3716	PTS system mannose fructose sorbose family IID component
FGE25_RS09480	COG3715	PTS system
FGE25_RS09485	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FGE25_RS09485	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
FGE25_RS09490	COG1253	flavin adenine dinucleotide binding
FGE25_RS09495	COG2200	EAL domain
FGE25_RS09500	COG1760	l-serine dehydratase
FGE25_RS09520	COG0251	oxidation-reduction process
FGE25_RS09525	COG1199	ATP-dependent helicase activity
FGE25_RS09530	COG1214	PFAM Peptidase M22, glycoprotease
FGE25_RS09535	COG3065	identical protein binding
FGE25_RS09540	COG0318	PFAM AMP-dependent synthetase and ligase
FGE25_RS09545	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
FGE25_RS09555	COG2894	cell division
FGE25_RS09560	COG0850	regulation of cytokinetic process
FGE25_RS09570	COG0179	Fumarylacetoacetate (FAA) hydrolase
FGE25_RS09590	COG2719	SpoVR family
FGE25_RS09605	COG3263	regulation of cellular component size
FGE25_RS09610	COG1619	proteins homologs of microcin C7 resistance protein MccF
FGE25_RS09615	COG0741	lytic transglycosylase activity
FGE25_RS09695	COG3773	Cell wall hydrolase
FGE25_RS09695	COG3409	Peptidoglycan-binding domain 1 protein
FGE25_RS09760	COG3501	Rhs element vgr protein
FGE25_RS09845	COG3501	Rhs element vgr protein
FGE25_RS09860	COG3209	COG3209 Rhs family protein
FGE25_RS09920	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
FGE25_RS09920	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
FGE25_RS09930	COG1053	succinate dehydrogenase
FGE25_RS09940	COG4565	transcriptional regulatory protein
FGE25_RS09945	COG3290	protein histidine kinase activity
FGE25_RS09960	COG3284	Transcriptional regulator
FGE25_RS09965	COG1012	belongs to the aldehyde dehydrogenase family
FGE25_RS09985	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
FGE25_RS10000	COG3685	Protein conserved in bacteria
FGE25_RS10005	COG3685	Protein conserved in bacteria
FGE25_RS10010	COG3729	General stress protein
FGE25_RS10015	COG3383	formate dehydrogenase (NAD+) activity
FGE25_RS10025	COG1271	oxidase subunit
FGE25_RS10030	COG1294	oxidase, subunit
FGE25_RS10035	COG1309	transcriptional regulator
FGE25_RS10040	COG0251	oxidation-reduction process
FGE25_RS10060	COG3546	catalase activity
FGE25_RS10065	COG3685	Protein conserved in bacteria
FGE25_RS10075	COG1846	Transcriptional regulator
FGE25_RS10080	COG1566	PFAM secretion protein HlyD family protein
FGE25_RS10085	COG2814	Major facilitator Superfamily
FGE25_RS10100	COG0789	Transcriptional regulator
FGE25_RS10105	COG2200	EAL domain
FGE25_RS10155	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
FGE25_RS10170	COG0583	DNA-binding transcription factor activity
FGE25_RS10185	COG1556	Lactate utilization protein
FGE25_RS10190	COG1139	Iron-sulfur cluster binding protein
FGE25_RS10195	COG0247	lactate metabolic process
FGE25_RS10200	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FGE25_RS10215	COG1403	HNH endonuclease
FGE25_RS10230	COG1278	Cold shock
FGE25_RS10250	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FGE25_RS10260	COG0745	RESPONSE REGULATOR receiver
FGE25_RS10265	COG5002	protein histidine kinase activity
FGE25_RS10285	COG2382	esterase
FGE25_RS10290	COG1566	PFAM secretion protein HlyD family protein
FGE25_RS10305	COG2207	Transcriptional regulator
FGE25_RS10320	COG3272	Protein of unknown function (DUF1722)
FGE25_RS10340	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FGE25_RS10355	COG0300	oxidoreductase activity
FGE25_RS10365	COG0789	Transcriptional regulator
FGE25_RS10400	COG3397	chitin binding
FGE25_RS10435	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
FGE25_RS10460	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
FGE25_RS10500	COG1396	sequence-specific DNA binding
FGE25_RS10515	COG2003	Belongs to the UPF0758 family
FGE25_RS10520	COG4974	Belongs to the 'phage' integrase family
FGE25_RS10570	COG0582	viral genome integration into host DNA
FGE25_RS10575	COG0012	GTP binding
FGE25_RS10595	COG0659	secondary active sulfate transmembrane transporter activity
FGE25_RS10600	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
FGE25_RS10625	COG2890	protein-(glutamine-N5) methyltransferase activity
FGE25_RS10630	COG3094	Invasion gene expression up-regulator, SirB
FGE25_RS10635	COG2912	Transglutaminase-like superfamily
FGE25_RS10645	COG0387	Pfam Sodium calcium exchanger
FGE25_RS10650	COG4572	Cation transport regulator
FGE25_RS10655	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
FGE25_RS10665	COG0840	transmembrane signaling receptor activity
FGE25_RS10670	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
FGE25_RS10680	COG4932	domain protein
FGE25_RS10685	COG2197	response regulator
FGE25_RS10690	COG3850	Histidine kinase
FGE25_RS10695	COG2223	nitrite transmembrane transporter activity
FGE25_RS10700	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
FGE25_RS10705	COG1140	nitrate reductase beta subunit
FGE25_RS10710	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
FGE25_RS10715	COG2181	nitrate reductase activity
FGE25_RS10720	COG0697	spore germination
FGE25_RS10725	COG1522	sequence-specific DNA binding
FGE25_RS10760	COG0788	formyltetrahydrofolate deformylase activity
FGE25_RS10770	COG1752	Esterase of the alpha-beta hydrolase superfamily
FGE25_RS10775	COG0745	RESPONSE REGULATOR receiver
FGE25_RS10780	COG1210	Utp--glucose-1-phosphate uridylyltransferase
FGE25_RS10790	COG1435	thymidine kinase activity
FGE25_RS10795	COG1012	belongs to the aldehyde dehydrogenase family
FGE25_RS10795	COG1454	alcohol dehydrogenase
FGE25_RS10800	COG2095	MarC family integral membrane protein
FGE25_RS10815	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FGE25_RS10820	COG0444	Belongs to the ABC transporter superfamily
FGE25_RS10855	COG2350	Protein conserved in bacteria
FGE25_RS10865	COG1607	acyl-coa hydrolase
FGE25_RS10885	COG3047	cAMP biosynthetic process
FGE25_RS10890	COG0038	chloride channel
FGE25_RS10905	COG0134	indole-3-glycerol-phosphate synthase activity
FGE25_RS10905	COG0135	phosphoribosylanthranilate isomerase activity
FGE25_RS10910	COG0512	Glutamine amidotransferase of anthranilate synthase
FGE25_RS10910	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FGE25_RS10915	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FGE25_RS10920	COG0613	PHP domain protein
FGE25_RS10925	COG0009	L-threonylcarbamoyladenylate synthase
FGE25_RS10930	COG1187	pseudouridine synthase activity
FGE25_RS10935	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
FGE25_RS10940	COG1028	Short-chain dehydrogenase reductase Sdr
FGE25_RS10945	COG0616	signal peptide processing
FGE25_RS10955	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FGE25_RS10980	COG0671	phosphoesterase, PA-phosphatase related
FGE25_RS10985	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
FGE25_RS10990	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
FGE25_RS10995	COG0284	orotidine-5'-phosphate decarboxylase activity
FGE25_RS11000	COG0023	Translation Initiation Factor
FGE25_RS11010	COG1349	DNA-binding transcription factor activity
FGE25_RS11020	COG1024	Enoyl-CoA hydratase
FGE25_RS11025	COG5001	Diguanylate cyclase
FGE25_RS11035	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FGE25_RS11035	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FGE25_RS11040	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
FGE25_RS11050	COG4172	Belongs to the ABC transporter superfamily
FGE25_RS11055	COG4171	peptide transport system, permease
FGE25_RS11060	COG4168	peptide transport system, permease
FGE25_RS11070	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
FGE25_RS11075	COG1842	Phage shock protein A
FGE25_RS11085	COG1983	PspC domain protein
FGE25_RS11095	COG3106	COG3106 Predicted ATPase
FGE25_RS11105	COG3283	Transcriptional regulator of aromatic amino acids metabolism
FGE25_RS11115	COG4948	Mandelate Racemase Muconate Lactonizing
FGE25_RS11120	COG2866	Carboxypeptidase
FGE25_RS11125	COG4166	transmembrane transport
FGE25_RS11135	COG3706	GGDEF domain
FGE25_RS11160	COG0513	Belongs to the DEAD box helicase family
FGE25_RS11180	COG1234	tRNA 3'-trailer cleavage
FGE25_RS11185	COG2329	Antibiotic biosynthesis monooxygenase
FGE25_RS11195	COG0674	pyruvate-flavodoxin oxidoreductase activity
FGE25_RS11195	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FGE25_RS11195	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
FGE25_RS11195	COG1013	pyruvate-flavodoxin oxidoreductase activity
FGE25_RS11205	COG4251	negative regulation of phosphorylation
FGE25_RS11205	COG2203	Gaf domain
FGE25_RS11205	COG3706	GGDEF domain
FGE25_RS11205	COG5001	Diguanylate cyclase
FGE25_RS11210	COG3042	response to heat
FGE25_RS11215	COG3187	Heat shock protein
FGE25_RS11220	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FGE25_RS11230	COG2911	Protein conserved in bacteria
FGE25_RS11240	COG3784	Protein of unknown function (DUF1318)
FGE25_RS11250	COG1643	Atp-dependent helicase
FGE25_RS11280	COG1434	Gram-negative-bacterium-type cell wall biogenesis
FGE25_RS11285	COG1012	belongs to the aldehyde dehydrogenase family
FGE25_RS11290	COG2755	lipolytic protein G-D-S-L family
FGE25_RS11290	COG0657	acetylesterase activity
FGE25_RS11295	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
FGE25_RS11300	COG3038	cytochrome b561
FGE25_RS11305	COG0477	Major facilitator Superfamily
FGE25_RS11330	COG0840	transmembrane signaling receptor activity
FGE25_RS11340	COG3416	Protein conserved in bacteria
FGE25_RS11345	COG0640	Transcriptional regulator
FGE25_RS11350	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
FGE25_RS11355	COG1393	Belongs to the ArsC family
FGE25_RS11360	COG0243	molybdopterin cofactor binding
FGE25_RS11365	COG0583	DNA-binding transcription factor activity
FGE25_RS11370	COG5383	Protein conserved in bacteria
FGE25_RS11385	COG0436	Aminotransferase
FGE25_RS11395	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
FGE25_RS11400	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FGE25_RS11410	COG1595	DNA-templated transcription, initiation
FGE25_RS11420	COG0753	catalase activity
FGE25_RS11425	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
FGE25_RS11430	COG0500	methyltransferase
FGE25_RS11435	COG2195	Cleaves the N-terminal amino acid of tripeptides
FGE25_RS11440	COG0747	negative chemotaxis
FGE25_RS11450	COG0697	spore germination
FGE25_RS11460	COG3135	benzoate transporter
FGE25_RS11465	COG1396	sequence-specific DNA binding
FGE25_RS11470	COG0826	peptidase U32
FGE25_RS11490	COG0778	Nitroreductase
FGE25_RS11505	COG1294	oxidase, subunit
FGE25_RS11510	COG1271	oxidase subunit
FGE25_RS11515	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FGE25_RS11520	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
FGE25_RS11525	COG3842	ATPase activity
FGE25_RS11530	COG1176	ABC-type spermidine putrescine transport system, permease component I
FGE25_RS11535	COG1177	transmembrane transport
FGE25_RS11540	COG1012	belongs to the aldehyde dehydrogenase family
FGE25_RS11560	COG3038	cytochrome b561
FGE25_RS11595	COG0747	negative chemotaxis
FGE25_RS11605	COG3238	Protein conserved in bacteria
FGE25_RS11610	COG1247	-acetyltransferase
FGE25_RS11620	COG2130	NADP-dependent
FGE25_RS11625	COG1802	Transcriptional regulator
FGE25_RS11640	COG4772	TonB-dependent receptor
FGE25_RS11670	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FGE25_RS11675	COG1473	amidohydrolase
FGE25_RS11680	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FGE25_RS11700	COG1126	abc transporter atp-binding protein
FGE25_RS11710	COG2271	Major facilitator Superfamily
FGE25_RS11720	COG1609	Transcriptional regulator
FGE25_RS11725	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
FGE25_RS11725	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
FGE25_RS11730	COG0625	glutathione transferase activity
FGE25_RS11745	COG1942	4-Oxalocrotonate Tautomerase
FGE25_RS11755	COG0657	acetylesterase activity
FGE25_RS11755	COG2755	lipolytic protein G-D-S-L family
FGE25_RS11760	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FGE25_RS11770	COG3842	ATPase activity
FGE25_RS11775	COG1840	ABC-type Fe3 transport system, periplasmic component
FGE25_RS11780	COG4149	molybdate abc transporter
FGE25_RS11785	COG2162	N-hydroxyarylamine O-acetyltransferase activity
FGE25_RS11810	COG0437	4 iron, 4 sulfur cluster binding
FGE25_RS11815	COG2864	formate dehydrogenase
FGE25_RS11820	COG2814	Major facilitator Superfamily
FGE25_RS11830	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FGE25_RS11845	COG0601	transmembrane transport
FGE25_RS11860	COG1064	alcohol dehydrogenase
FGE25_RS11870	COG0488	(ABC) transporter
FGE25_RS11890	COG0463	Glycosyl transferase, family 2
FGE25_RS11895	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FGE25_RS11905	COG2223	nitrite transmembrane transporter activity
FGE25_RS11920	COG0840	transmembrane signaling receptor activity
FGE25_RS11925	COG1126	abc transporter atp-binding protein
FGE25_RS11930	COG0765	amino acid transport
FGE25_RS11935	COG4597	amino acid ABC transporter
FGE25_RS11940	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FGE25_RS11960	COG1802	Transcriptional regulator
FGE25_RS11965	COG2200	EAL domain
FGE25_RS11970	COG4251	negative regulation of phosphorylation
FGE25_RS11970	COG2203	Gaf domain
FGE25_RS11970	COG3706	GGDEF domain
FGE25_RS11970	COG5001	Diguanylate cyclase
FGE25_RS11980	COG0028	Belongs to the TPP enzyme family
FGE25_RS12030	COG4566	intracellular signal transduction
FGE25_RS12050	COG2814	Major facilitator Superfamily
FGE25_RS12080	COG0076	glutamate decarboxylase activity
FGE25_RS12085	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
FGE25_RS12090	COG0527	aspartate kinase activity
FGE25_RS12095	COG4628	conserved protein (DUF2132)
FGE25_RS12130	COG1275	C4-dicarboxylate transporter malic acid transport protein
FGE25_RS12140	COG1366	Belongs to the anti-sigma-factor antagonist family
FGE25_RS12205	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
FGE25_RS12210	COG2864	formate dehydrogenase
FGE25_RS12215	COG0437	4 iron, 4 sulfur cluster binding
FGE25_RS12235	COG4221	oxidoreductase activity
FGE25_RS12240	COG0583	DNA-binding transcription factor activity
FGE25_RS12245	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
FGE25_RS12320	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FGE25_RS12325	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FGE25_RS12335	COG2205	protein histidine kinase activity
FGE25_RS12340	COG3604	Transcriptional regulator
FGE25_RS12355	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
FGE25_RS12360	COG0840	transmembrane signaling receptor activity
FGE25_RS12365	COG1012	belongs to the aldehyde dehydrogenase family
FGE25_RS12370	COG0583	DNA-binding transcription factor activity
FGE25_RS12375	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FGE25_RS12385	COG3781	membrane
FGE25_RS12390	COG0246	Mannitol dehydrogenase
FGE25_RS12400	COG3706	GGDEF domain
FGE25_RS12405	COG3706	GGDEF domain
FGE25_RS12410	COG2199	diguanylate cyclase activity
FGE25_RS12425	COG0840	transmembrane signaling receptor activity
FGE25_RS12430	COG1012	belongs to the aldehyde dehydrogenase family
FGE25_RS12435	COG0583	DNA-binding transcription factor activity
FGE25_RS12445	COG0039	L-malate dehydrogenase activity
FGE25_RS12460	COG2814	Major facilitator Superfamily
FGE25_RS12475	COG1846	Transcriptional regulator
FGE25_RS12490	COG0697	spore germination
FGE25_RS12495	COG2814	Major facilitator Superfamily
FGE25_RS12500	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
FGE25_RS12530	COG0339	signal peptide processing
FGE25_RS12535	COG4221	oxidoreductase activity
FGE25_RS12540	COG1802	Transcriptional regulator
FGE25_RS12550	COG0246	Mannitol dehydrogenase
FGE25_RS12565	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FGE25_RS12580	COG0583	DNA-binding transcription factor activity
FGE25_RS12590	COG0243	molybdopterin cofactor binding
FGE25_RS12595	COG0437	4 iron, 4 sulfur cluster binding
FGE25_RS12600	COG3302	dmso reductase anchor subunit
FGE25_RS12605	COG3381	protein complex oligomerization
FGE25_RS12615	COG2199	diguanylate cyclase activity
FGE25_RS12615	COG2203	Gaf domain
FGE25_RS12640	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
FGE25_RS12645	COG1940	carbohydrate kinase activity
FGE25_RS12650	COG0583	DNA-binding transcription factor activity
FGE25_RS12655	COG2814	Major facilitator Superfamily
FGE25_RS12660	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
FGE25_RS12670	COG3591	Belongs to the peptidase S1B family
FGE25_RS12685	COG2076	Multidrug Resistance protein
FGE25_RS12690	COG0628	permease
FGE25_RS12695	COG4943	cyclic-guanylate-specific phosphodiesterase activity
FGE25_RS12700	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FGE25_RS12705	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FGE25_RS12710	COG5002	protein histidine kinase activity
FGE25_RS12750	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
FGE25_RS12765	COG1028	Short-chain dehydrogenase reductase Sdr
FGE25_RS12770	COG0280	phosphate acetyltransferase
FGE25_RS12775	COG3426	butyrate kinase activity
FGE25_RS12785	COG2840	Smr protein MutS2
FGE25_RS12790	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FGE25_RS12795	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FGE25_RS12805	COG0668	transmembrane transport
FGE25_RS12810	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
FGE25_RS12815	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
FGE25_RS12825	COG0531	amino acid
FGE25_RS12830	COG3136	membrane protein required for alginate biosynthesis
FGE25_RS12835	COG0745	RESPONSE REGULATOR receiver
FGE25_RS12840	COG2205	protein histidine kinase activity
FGE25_RS12850	COG0114	fumarate hydratase activity
FGE25_RS12865	COG5339	Protein conserved in bacteria
FGE25_RS12870	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FGE25_RS12870	COG1263	PTS System
FGE25_RS12875	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
FGE25_RS12885	COG0673	inositol 2-dehydrogenase activity
FGE25_RS12925	COG4659	FMN binding
FGE25_RS12935	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
FGE25_RS12960	COG0625	glutathione transferase activity
FGE25_RS12965	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
FGE25_RS12980	COG3895	Periplasmic Protein
FGE25_RS12985	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
FGE25_RS12990	COG3133	Outer membrane lipoprotein
FGE25_RS13005	COG1566	PFAM secretion protein HlyD family protein
FGE25_RS13010	COG1289	transmembrane transporter activity
FGE25_RS13015	COG2032	superoxide dismutase activity
FGE25_RS13020	COG4989	oxidoreductase activity
FGE25_RS13025	COG3313	Fe-S protein
FGE25_RS13030	COG1309	transcriptional regulator
FGE25_RS13035	COG1902	pentaerythritol trinitrate reductase activity
FGE25_RS13040	COG0346	lactoylglutathione lyase activity
FGE25_RS13050	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
FGE25_RS13055	COG0791	NLP P60 protein
FGE25_RS13060	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
FGE25_RS13065	COG2814	Major facilitator Superfamily
FGE25_RS13080	COG0583	DNA-binding transcription factor activity
FGE25_RS13085	COG2814	Major facilitator Superfamily
FGE25_RS13090	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FGE25_RS13095	COG0307	riboflavin synthase, alpha
FGE25_RS13115	COG3468	outer membrane autotransporter barrel domain protein
FGE25_RS13115	COG3468	outer membrane autotransporter barrel domain protein
FGE25_RS13135	COG1376	ErfK ybiS ycfS ynhG family protein
FGE25_RS13140	COG2166	iron-sulfur cluster assembly
FGE25_RS13150	COG0719	Fe-S assembly protein
FGE25_RS13155	COG0396	ATPase activity
FGE25_RS13160	COG0719	Fe-S assembly protein
FGE25_RS13165	COG0316	Belongs to the HesB IscA family
FGE25_RS13175	COG2267	carboxylic ester hydrolase activity
FGE25_RS13190	COG1560	Kdo2-lipid A biosynthetic process
FGE25_RS13195	COG2050	protein possibly involved in aromatic compounds catabolism
FGE25_RS13200	COG0277	FAD linked oxidase domain protein
FGE25_RS13200	COG0247	lactate metabolic process
FGE25_RS13205	COG0628	permease
FGE25_RS13220	COG1472	Belongs to the glycosyl hydrolase 3 family
FGE25_RS13225	COG2211	Major facilitator Superfamily
FGE25_RS13230	COG0574	Belongs to the PEP-utilizing enzyme family
FGE25_RS13230	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FGE25_RS13240	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
FGE25_RS13245	COG4256	Hemin uptake protein
FGE25_RS13260	COG0791	NLP P60 protein
FGE25_RS13270	COG0386	Belongs to the glutathione peroxidase family
FGE25_RS13280	COG0776	regulation of translation
FGE25_RS13285	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FGE25_RS13285	COG0072	phenylalanine-tRNA ligase activity
FGE25_RS13335	COG3137	Salt-induced outer membrane protein
FGE25_RS13340	COG1105	Belongs to the carbohydrate kinase PfkB family
FGE25_RS13360	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FGE25_RS13365	COG1028	Short-chain dehydrogenase reductase Sdr
FGE25_RS13370	COG1988	membrane-bound metal-dependent
FGE25_RS13385	COG0753	catalase activity
FGE25_RS13390	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FGE25_RS13400	COG0322	excinuclease ABC activity
FGE25_RS13410	COG3678	ATP-independent chaperone mediated protein folding
FGE25_RS13420	COG3724	N-succinylarginine dihydrolase activity
FGE25_RS13425	COG1012	belongs to the aldehyde dehydrogenase family
FGE25_RS13440	COG0708	Exodeoxyribonuclease III
FGE25_RS13445	COG2897	thiosulfate sulfurtransferase activity
FGE25_RS13450	COG0494	nUDIX hydrolase
FGE25_RS13465	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FGE25_RS13470	COG0709	Synthesizes selenophosphate from selenide and ATP
FGE25_RS13490	COG0778	Nitroreductase
FGE25_RS13495	COG0616	signal peptide processing
FGE25_RS13500	COG0252	asparaginase activity
FGE25_RS13505	COG1335	isochorismatase
FGE25_RS13510	COG3139	Protein of unknown function (DUF1315)
FGE25_RS13520	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
FGE25_RS13530	COG0656	L-ascorbic acid biosynthetic process
FGE25_RS13535	COG3713	MltA-interacting MipA family protein
FGE25_RS13545	COG1696	Membrane protein involved in D-alanine export
FGE25_RS13550	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FGE25_RS13560	COG2766	serine protein kinase
FGE25_RS13565	COG2718	Belongs to the UPF0229 family
FGE25_RS13570	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
FGE25_RS13580	COG0765	amino acid transport
FGE25_RS13585	COG4597	amino acid ABC transporter
FGE25_RS13595	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FGE25_RS13600	COG2207	Transcriptional regulator
FGE25_RS13605	COG2807	transmembrane transport
FGE25_RS13610	COG0504	CTP synthase activity
FGE25_RS13615	COG1683	Conserved Protein
FGE25_RS13620	COG3189	MarR family transcriptional regulator
FGE25_RS13630	COG3042	response to heat
FGE25_RS13635	COG2199	diguanylate cyclase activity
FGE25_RS13635	COG2203	Gaf domain
FGE25_RS13645	COG5001	Diguanylate cyclase
FGE25_RS13665	COG0840	transmembrane signaling receptor activity
FGE25_RS13750	COG0538	isocitrate dehydrogenase activity
FGE25_RS13760	COG2135	peptidase activity
FGE25_RS13770	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
FGE25_RS13810	COG3772	lysozyme
FGE25_RS13830	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
FGE25_RS13870	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
FGE25_RS13905	COG0582	viral genome integration into host DNA
FGE25_RS13915	COG0538	isocitrate dehydrogenase activity
FGE25_RS13920	COG1187	pseudouridine synthase activity
FGE25_RS13935	COG2915	High frequency lysogenization protein hflD homolog
FGE25_RS13940	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
FGE25_RS13945	COG0745	RESPONSE REGULATOR receiver
FGE25_RS13955	COG2850	peptidyl-arginine hydroxylation
FGE25_RS13970	COG1176	ABC-type spermidine putrescine transport system, permease component I
FGE25_RS13975	COG1177	transmembrane transport
FGE25_RS13980	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
FGE25_RS13985	COG2205	protein histidine kinase activity
FGE25_RS14000	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
FGE25_RS14010	COG4591	ABC-type transport system involved in lipoprotein release permease component
FGE25_RS14020	COG4591	ABC-type transport system involved in lipoprotein release permease component
FGE25_RS14025	COG4763	Acyl-transferase
FGE25_RS14030	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
FGE25_RS14035	COG1388	LysM domain
FGE25_RS14035	COG1376	ErfK ybiS ycfS ynhG family protein
FGE25_RS14045	COG1309	transcriptional regulator
FGE25_RS14050	COG3134	Outer membrane lipoprotein
FGE25_RS14055	COG1252	NADH dehydrogenase
FGE25_RS14070	COG0510	thiamine kinase activity
FGE25_RS14075	COG3417	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b)
FGE25_RS14080	COG5633	Lipoprotein
FGE25_RS14085	COG0537	adenosine 5'-monophosphoramidase activity
FGE25_RS14090	COG4773	Receptor
FGE25_RS14100	COG0084	hydrolase, TatD family'
FGE25_RS14105	COG0470	DNA polymerase III
FGE25_RS14115	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
FGE25_RS14120	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FGE25_RS14125	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FGE25_RS14135	COG1028	Short-chain dehydrogenase reductase Sdr
FGE25_RS14140	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
FGE25_RS14160	COG1399	metal-binding, possibly nucleic acid-binding protein
FGE25_RS14170	COG0823	Involved in the tonB-independent uptake of proteins
FGE25_RS14170	COG1506	peptidase
FGE25_RS14180	COG1530	ribonuclease E activity
FGE25_RS14185	COG0583	DNA-binding transcription factor activity
FGE25_RS14190	COG2814	Major facilitator Superfamily
FGE25_RS14200	COG1256	bacterial-type flagellum assembly
FGE25_RS14220	COG4786	Flagellar basal body rod
FGE25_RS14225	COG4787	bacterial-type flagellum-dependent cell motility
FGE25_RS14230	COG1749	Flagellar hook protein flgE
FGE25_RS14235	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
FGE25_RS14240	COG1558	bacterial-type flagellum-dependent cell motility
FGE25_RS14260	COG3418	PFAM FlgN family protein
FGE25_RS14265	COG0728	peptidoglycan biosynthetic process
FGE25_RS14275	COG3132	Protein of unknown function, DUF480
FGE25_RS14280	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FGE25_RS14290	COG2999	glutathione oxidoreductase activity
FGE25_RS14325	COG3038	cytochrome b561
FGE25_RS14340	COG1560	Kdo2-lipid A biosynthetic process
FGE25_RS14355	COG5645	(Lipo)protein
FGE25_RS14375	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
FGE25_RS14425	COG3381	protein complex oligomerization
FGE25_RS14430	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
FGE25_RS14435	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FGE25_RS14450	COG0604	alcohol dehydrogenase
FGE25_RS14455	COG0583	DNA-binding transcription factor activity
FGE25_RS14465	COG0583	DNA-binding transcription factor activity
FGE25_RS14495	COG0840	transmembrane signaling receptor activity
FGE25_RS14515	COG1028	Short-chain dehydrogenase reductase Sdr
FGE25_RS14525	COG2207	Transcriptional regulator
FGE25_RS14545	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FGE25_RS14555	COG1028	Short-chain dehydrogenase reductase Sdr
FGE25_RS14590	COG0745	RESPONSE REGULATOR receiver
FGE25_RS14605	COG1028	Short-chain dehydrogenase reductase Sdr
FGE25_RS14620	COG0583	DNA-binding transcription factor activity
FGE25_RS14630	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
FGE25_RS14635	COG2130	NADP-dependent
FGE25_RS14640	COG2040	homocysteine
FGE25_RS14645	COG0833	amino acid
FGE25_RS14660	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FGE25_RS14665	COG0765	amino acid transport
FGE25_RS14700	COG1733	regulation of RNA biosynthetic process
FGE25_RS14705	COG1028	Short-chain dehydrogenase reductase Sdr
FGE25_RS14755	COG0583	DNA-binding transcription factor activity
FGE25_RS14760	COG4221	oxidoreductase activity
FGE25_RS14775	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FGE25_RS14780	COG4977	sequence-specific DNA binding
FGE25_RS14790	COG5434	Belongs to the glycosyl hydrolase 28 family
FGE25_RS14800	COG1605	Chorismate mutase
FGE25_RS14805	COG1702	phosphate starvation-inducible protein PhoH
FGE25_RS14810	COG2837	iron assimilation
FGE25_RS14820	COG0672	)-iron permease
FGE25_RS14825	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FGE25_RS14835	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FGE25_RS14850	COG1069	ribulokinase activity
FGE25_RS14855	COG1172	Belongs to the binding-protein-dependent transport system permease family
FGE25_RS14860	COG1172	Belongs to the binding-protein-dependent transport system permease family
FGE25_RS14865	COG1129	ABC transporter
FGE25_RS14885	COG1309	transcriptional regulator
FGE25_RS14895	COG3729	General stress protein
FGE25_RS14915	COG1733	regulation of RNA biosynthetic process
FGE25_RS14920	COG4221	oxidoreductase activity
FGE25_RS14930	COG3706	GGDEF domain
FGE25_RS14960	COG2177	Part of the ABC transporter FtsEX involved in
FGE25_RS14970	COG1136	(ABC) transporter
FGE25_RS14985	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FGE25_RS14995	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FGE25_RS15000	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FGE25_RS15010	COG0736	holo-[acyl-carrier-protein] synthase activity
FGE25_RS15015	COG2831	hemolysin activation secretion protein
FGE25_RS15020	COG3710	Transcriptional regulator
FGE25_RS15040	COG0670	Belongs to the BI1 family
FGE25_RS15055	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
FGE25_RS15065	COG1832	CoA-binding protein
FGE25_RS15075	COG0210	DNA helicase
FGE25_RS15080	COG3304	Inner membrane component domain
FGE25_RS15085	COG1289	transmembrane transporter activity
FGE25_RS15090	COG3070	regulator of competence-specific genes
FGE25_RS15110	COG1067	ATP-dependent peptidase activity
FGE25_RS15120	COG3130	regulation of translation
FGE25_RS15125	COG3009	Protein conserved in bacteria
FGE25_RS15130	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
FGE25_RS15130	COG3008	intermembrane lipid transfer
FGE25_RS15135	COG2995	paraquat-inducible protein a
FGE25_RS15140	COG0488	(ABC) transporter
FGE25_RS15150	COG0633	Ferredoxin
FGE25_RS15150	COG3217	Mosc domain protein beta barrel domain protein
FGE25_RS15165	COG0431	NADPH-dependent FMN reductase
FGE25_RS15170	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FGE25_RS15180	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FGE25_RS15185	COG1116	anion transmembrane transporter activity
FGE25_RS15190	COG0308	aminopeptidase N
FGE25_RS15205	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
FGE25_RS15210	COG1448	Aminotransferase
FGE25_RS15215	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FGE25_RS15220	COG3108	Peptidase M15
FGE25_RS15225	COG2989	Protein conserved in bacteria
FGE25_RS15235	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
FGE25_RS15245	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FGE25_RS15250	COG1434	Gram-negative-bacterium-type cell wall biogenesis
FGE25_RS15255	COG3173	Aminoglycoside phosphotransferase
FGE25_RS15265	COG2835	tetraacyldisaccharide 4'-kinase activity
FGE25_RS15270	COG3214	Protein conserved in bacteria
FGE25_RS15285	COG2333	competence protein COMEC
FGE25_RS15285	COG0658	competence protein
FGE25_RS15295	COG0539	negative regulation of cytoplasmic translation
FGE25_RS15315	COG2323	membrane
FGE25_RS15320	COG1944	ATP diphosphatase activity
FGE25_RS15325	COG2116	formate transmembrane transporter activity
FGE25_RS15330	COG1882	Formate acetyltransferase
FGE25_RS15335	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
FGE25_RS15340	COG0477	Major facilitator Superfamily
FGE25_RS15350	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
FGE25_RS15360	COG1674	ftsk spoiiie
FGE25_RS15360	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
FGE25_RS15370	COG0492	ferredoxin-NADP+ reductase activity
FGE25_RS15375	COG4988	ABC transporter
FGE25_RS15380	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
FGE25_RS15405	COG3706	GGDEF domain
FGE25_RS15410	COG0542	response to heat
FGE25_RS15415	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
FGE25_RS15420	COG1278	Cold shock
FGE25_RS15430	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FGE25_RS15435	COG2990	Protein conserved in bacteria
FGE25_RS15440	COG3593	DNA synthesis involved in DNA repair
FGE25_RS15445	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
FGE25_RS15450	COG2431	L-lysine efflux transmembrane transporter activity
FGE25_RS15455	COG1151	hydroxylamine reductase activity
FGE25_RS15460	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FGE25_RS15470	COG0028	Belongs to the TPP enzyme family
FGE25_RS15475	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
FGE25_RS15480	COG0702	epimerase
FGE25_RS15485	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FGE25_RS15495	COG3023	N-Acetylmuramoyl-L-alanine amidase
FGE25_RS15500	COG0393	Putative heavy-metal-binding
FGE25_RS15510	COG1126	abc transporter atp-binding protein
FGE25_RS15515	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FGE25_RS15520	COG4215	(ABC) transporter
FGE25_RS15525	COG4160	amino acid transport
FGE25_RS15530	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FGE25_RS15535	COG0243	molybdopterin cofactor binding
FGE25_RS15550	COG1177	transmembrane transport
FGE25_RS15555	COG1176	ABC-type spermidine putrescine transport system, permease component I
FGE25_RS15560	COG3842	ATPase activity
FGE25_RS15565	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
FGE25_RS15580	COG0778	Nitroreductase
FGE25_RS15585	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
FGE25_RS15690	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
FGE25_RS15715	COG3226	Transcriptional regulator
FGE25_RS15720	COG0738	Major facilitator superfamily
FGE25_RS15725	COG2814	Major facilitator Superfamily
FGE25_RS15730	COG0671	phosphoesterase, PA-phosphatase related
FGE25_RS15735	COG1349	DNA-binding transcription factor activity
FGE25_RS15740	COG1686	Belongs to the peptidase S11 family
FGE25_RS15745	COG0625	glutathione transferase activity
FGE25_RS15760	COG0583	DNA-binding transcription factor activity
FGE25_RS15770	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
FGE25_RS15775	COG2133	pyrroloquinoline quinone binding
FGE25_RS15815	COG2819	hydrolase of the alpha beta superfamily
FGE25_RS15830	COG1846	Transcriptional regulator
FGE25_RS15830	COG0456	acetyltransferase
FGE25_RS15840	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FGE25_RS15855	COG4172	Belongs to the ABC transporter superfamily
FGE25_RS15860	COG1446	asparaginase
FGE25_RS15865	COG0303	'Molybdopterin
FGE25_RS15875	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
FGE25_RS15885	COG0561	phosphatase activity
FGE25_RS15900	COG2271	Major facilitator Superfamily
FGE25_RS15910	COG0488	(ABC) transporter
FGE25_RS15915	COG1376	ErfK ybiS ycfS ynhG family protein
FGE25_RS15920	COG2188	Transcriptional regulator
FGE25_RS15925	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FGE25_RS15930	COG2723	6-phospho-beta-galactosidase activity
FGE25_RS15935	COG0667	Aldo Keto reductase
FGE25_RS15945	COG2814	Major facilitator Superfamily
FGE25_RS15950	COG1566	PFAM secretion protein HlyD family protein
FGE25_RS15955	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
FGE25_RS15960	COG1321	iron dependent repressor
FGE25_RS15970	COG2194	sulfuric ester hydrolase activity
FGE25_RS15975	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
FGE25_RS15985	COG0783	Belongs to the Dps family
FGE25_RS15990	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FGE25_RS15995	COG0765	amino acid transport
FGE25_RS16000	COG1126	abc transporter atp-binding protein
FGE25_RS16005	COG0668	transmembrane transport
FGE25_RS16020	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
FGE25_RS16030	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FGE25_RS16045	COG3711	transcriptional antiterminator
FGE25_RS16050	COG2190	(PTS) system
FGE25_RS16050	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FGE25_RS16050	COG1263	PTS System
FGE25_RS16055	COG2723	6-phospho-beta-galactosidase activity
FGE25_RS16060	COG2723	6-phospho-beta-galactosidase activity
FGE25_RS16070	COG0513	Belongs to the DEAD box helicase family
FGE25_RS16075	COG1309	transcriptional regulator
FGE25_RS16080	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FGE25_RS16085	COG1131	(ABC) transporter
FGE25_RS16090	COG0842	Transport permease protein
FGE25_RS16095	COG0842	Transport permease protein
FGE25_RS16105	COG3568	Endonuclease Exonuclease Phosphatase
FGE25_RS16110	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FGE25_RS16115	COG0392	lysyltransferase activity
FGE25_RS16125	COG0670	Belongs to the BI1 family
FGE25_RS16130	COG0314	molybdopterin synthase activity
FGE25_RS16135	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
FGE25_RS16145	COG0521	Mo-molybdopterin cofactor biosynthetic process
FGE25_RS16160	COG2194	sulfuric ester hydrolase activity
FGE25_RS16170	COG0642	Histidine kinase
FGE25_RS16185	COG0410	ABC transporter
FGE25_RS16210	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FGE25_RS16215	COG1881	PFAM PEBP family protein
FGE25_RS16220	COG4677	pectinesterase activity
FGE25_RS16230	COG0561	phosphatase activity
FGE25_RS16240	COG4149	molybdate abc transporter
FGE25_RS16245	COG0725	ABC transporter, periplasmic molybdate-binding protein
FGE25_RS16255	COG3585	molybdate ion transport
FGE25_RS16255	COG2005	Transcriptional regulator
FGE25_RS16260	COG1119	ATPase activity
FGE25_RS16275	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FGE25_RS16280	COG1085	galactose-1-phosphate uridylyltransferase
FGE25_RS16290	COG2017	converts alpha-aldose to the beta-anomer
FGE25_RS16300	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
FGE25_RS16315	COG3201	nicotinamide mononucleotide transporter
FGE25_RS16320	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
FGE25_RS16350	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
FGE25_RS16355	COG2885	chlorophyll binding
FGE25_RS16365	COG3064	Membrane
FGE25_RS16370	COG0848	biopolymer transport protein
FGE25_RS16375	COG0811	peptide transport
FGE25_RS16380	COG0824	Thioesterase
FGE25_RS16385	COG3790	cyd operon protein YbgE
FGE25_RS16390	COG4890	Cyd operon protein YbgT
FGE25_RS16395	COG1294	oxidase, subunit
FGE25_RS16400	COG1271	oxidase subunit
FGE25_RS16405	COG2814	Major facilitator Superfamily
FGE25_RS16410	COG1733	regulation of RNA biosynthetic process
FGE25_RS16415	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
FGE25_RS16425	COG0508	dehydrogenase complex catalyzes the overall conversion of
FGE25_RS16430	COG0567	Dehydrogenase, E1 component
FGE25_RS16440	COG1053	succinate dehydrogenase
FGE25_RS16445	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
FGE25_RS16450	COG2009	succinate dehydrogenase
FGE25_RS16455	COG0372	Belongs to the citrate synthase family
FGE25_RS16465	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
FGE25_RS16470	COG1984	allophanate hydrolase subunit 2
FGE25_RS16475	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
FGE25_RS16480	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
FGE25_RS16505	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
FGE25_RS16510	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
FGE25_RS16520	COG2205	protein histidine kinase activity
FGE25_RS16525	COG0745	RESPONSE REGULATOR receiver
FGE25_RS16535	COG0033	Phosphoglucomutase
FGE25_RS16545	COG0596	Alpha beta hydrolase
FGE25_RS16560	COG0735	belongs to the Fur family
FGE25_RS16575	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FGE25_RS16585	COG2190	(PTS) system
FGE25_RS16585	COG1263	PTS System
FGE25_RS16585	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FGE25_RS16595	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
FGE25_RS16600	COG1846	Transcriptional regulator
FGE25_RS16600	COG1940	carbohydrate kinase activity
FGE25_RS16605	COG0647	UMP catabolic process
FGE25_RS16610	COG0367	asparagine synthase
FGE25_RS16655	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FGE25_RS16665	COG1702	phosphate starvation-inducible protein PhoH
FGE25_RS16670	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
FGE25_RS16675	COG4535	Mg2 and Co2 transporter CorC
FGE25_RS16680	COG0815	Transfers the fatty acyl group on membrane lipoproteins
FGE25_RS16690	COG0765	amino acid transport
FGE25_RS16695	COG0765	amino acid transport
FGE25_RS16700	COG1126	abc transporter atp-binding protein
FGE25_RS16705	COG2888	peptidyl-tyrosine sulfation
FGE25_RS16720	COG1466	dna polymerase III delta subunit
FGE25_RS16730	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FGE25_RS16740	COG0799	negative regulation of ribosome biogenesis
FGE25_RS16750	COG0768	penicillin binding
FGE25_RS16755	COG0772	Belongs to the SEDS family
FGE25_RS16760	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
FGE25_RS16765	COG1686	Belongs to the peptidase S11 family
FGE25_RS16770	COG2921	Belongs to the UPF0250 family
FGE25_RS16775	COG0321	lipoyl(octanoyl) transferase activity
FGE25_RS16780	COG0583	DNA-binding transcription factor activity
FGE25_RS16790	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FGE25_RS16795	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FGE25_RS16805	COG1278	Cold shock
FGE25_RS16815	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FGE25_RS16820	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FGE25_RS16840	COG3069	C4-dicarboxylate transmembrane transporter activity
FGE25_RS16845	COG3719	Belongs to the RNase T2 family
FGE25_RS16850	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FGE25_RS16855	COG0589	response to stress
FGE25_RS16865	COG0450	alkyl hydroperoxide reductase
FGE25_RS16870	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FGE25_RS16875	COG0436	Aminotransferase
FGE25_RS16885	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
FGE25_RS16900	COG0840	transmembrane signaling receptor activity
FGE25_RS16930	COG3210	domain, Protein
FGE25_RS16945	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FGE25_RS16960	COG1120	ATPase activity
FGE25_RS16965	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FGE25_RS16970	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FGE25_RS16975	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FGE25_RS17000	COG1120	ATPase activity
FGE25_RS17005	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FGE25_RS17045	COG1172	Belongs to the binding-protein-dependent transport system permease family
FGE25_RS17050	COG1129	ABC transporter
FGE25_RS17055	COG0371	Dehydrogenase
FGE25_RS17075	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FGE25_RS17080	COG1309	transcriptional regulator
FGE25_RS17090	COG2879	small protein
FGE25_RS17095	COG1966	Carbon starvation protein
FGE25_RS17100	COG2050	protein possibly involved in aromatic compounds catabolism
FGE25_RS17105	COG1028	Short-chain dehydrogenase reductase Sdr
FGE25_RS17110	COG3433	isochorismatase activity
FGE25_RS17110	COG1535	isochorismatase
FGE25_RS17115	COG1021	2,3-dihydroxybenzoate-AMP ligase
FGE25_RS17120	COG1169	isochorismate synthase
FGE25_RS17125	COG4592	Periplasmic binding protein
FGE25_RS17135	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FGE25_RS17140	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FGE25_RS17145	COG1120	ATPase activity
FGE25_RS17155	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FGE25_RS17155	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
FGE25_RS17160	COG3251	PFAM MbtH domain protein
FGE25_RS17165	COG2382	esterase
FGE25_RS17170	COG4771	TonB-dependent receptor
FGE25_RS17175	COG0840	transmembrane signaling receptor activity
FGE25_RS17190	COG4221	oxidoreductase activity
FGE25_RS17195	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
FGE25_RS17225	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
FGE25_RS17290	COG4558	Periplasmic binding protein
FGE25_RS17295	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FGE25_RS17300	COG1120	ATPase activity
FGE25_RS17330	COG0444	Belongs to the ABC transporter superfamily
FGE25_RS17340	COG0601	transmembrane transport
FGE25_RS17350	COG2267	carboxylic ester hydrolase activity
FGE25_RS17360	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
FGE25_RS17370	COG0840	transmembrane signaling receptor activity
FGE25_RS17380	COG1902	pentaerythritol trinitrate reductase activity
FGE25_RS17405	COG1028	Short-chain dehydrogenase reductase Sdr
FGE25_RS17410	COG0583	DNA-binding transcription factor activity
FGE25_RS17430	COG2190	(PTS) system
FGE25_RS17430	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FGE25_RS17430	COG1263	PTS System
FGE25_RS17460	COG0583	DNA-binding transcription factor activity
FGE25_RS17465	COG0427	acetyl-CoA hydrolase
FGE25_RS17470	COG1024	Enoyl-CoA hydratase
FGE25_RS17475	COG1703	isobutyryl-CoA mutase activity
FGE25_RS17480	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FGE25_RS17480	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FGE25_RS17495	COG0071	Belongs to the small heat shock protein (HSP20) family
FGE25_RS17550	COG3772	lysozyme
FGE25_RS17640	COG0582	viral genome integration into host DNA
FGE25_RS17705	COG2501	S4 domain
FGE25_RS17710	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FGE25_RS17710	COG2190	(PTS) system
FGE25_RS17710	COG1263	PTS System
FGE25_RS17715	COG1609	Transcriptional regulator
FGE25_RS17720	COG1988	membrane-bound metal-dependent
FGE25_RS17730	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
FGE25_RS17740	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
FGE25_RS17745	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
FGE25_RS17765	COG1464	Belongs to the NlpA lipoprotein family
FGE25_RS17775	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
FGE25_RS17780	COG4181	ATPase activity
FGE25_RS17785	COG2755	lipolytic protein G-D-S-L family
FGE25_RS17790	COG0300	oxidoreductase activity
FGE25_RS17795	COG3118	belongs to the thioredoxin family
FGE25_RS17800	COG0330	HflC and HflK could
FGE25_RS17805	COG1585	Membrane protein implicated in regulation of membrane protease activity
FGE25_RS17825	COG2314	TM2 domain
FGE25_RS17835	COG3735	TraB family
FGE25_RS17845	COG0737	Belongs to the 5'-nucleotidase family
FGE25_RS17850	COG2223	nitrite transmembrane transporter activity
FGE25_RS17855	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FGE25_RS17855	COG4651	solute:proton antiporter activity
FGE25_RS17860	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FGE25_RS17865	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
FGE25_RS17890	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
FGE25_RS17900	COG2832	Protein of unknown function (DUF454)
FGE25_RS17905	COG3923	Primosomal replication protein n
FGE25_RS17915	COG1196	nuclear chromosome segregation
FGE25_RS17915	COG3264	Mechanosensitive ion channel
FGE25_RS17920	COG1309	transcriptional regulator
FGE25_RS17925	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FGE25_RS17930	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FGE25_RS17945	COG0110	maltose O-acetyltransferase activity
FGE25_RS17965	COG0257	Belongs to the bacterial ribosomal protein bL36 family
FGE25_RS17990	COG2011	ABC-type metal ion transport system permease component
FGE25_RS17995	COG1263	PTS System
FGE25_RS17995	COG2190	(PTS) system
FGE25_RS17995	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FGE25_RS18000	COG4948	Mandelate Racemase Muconate Lactonizing
FGE25_RS18010	COG4943	cyclic-guanylate-specific phosphodiesterase activity
FGE25_RS18020	COG5507	3-demethylubiquinone-9 3-methyltransferase
FGE25_RS18025	COG3250	beta-galactosidase activity
FGE25_RS18030	COG1609	Transcriptional regulator
FGE25_RS18050	COG2364	Membrane
FGE25_RS18055	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FGE25_RS18075	COG3695	enzyme binding
FGE25_RS18080	COG3126	Type III secretion system lipoprotein chaperone (YscW)
FGE25_RS18085	COG1946	Acyl-CoA thioesterase
FGE25_RS18090	COG0004	ammonium transporteR
FGE25_RS18095	COG0347	Belongs to the P(II) protein family
FGE25_RS18100	COG1132	(ABC) transporter
FGE25_RS18105	COG1132	(ABC) transporter
FGE25_RS18110	COG1522	sequence-specific DNA binding
FGE25_RS18115	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FGE25_RS18120	COG0561	phosphatase activity
FGE25_RS18125	COG4533	DNA binding
FGE25_RS18135	COG0824	Thioesterase
FGE25_RS18145	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FGE25_RS18150	COG0776	regulation of translation
FGE25_RS18155	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
FGE25_RS18175	COG0271	Belongs to the BolA IbaG family
FGE25_RS18180	COG3056	Lipoprotein
FGE25_RS18185	COG2223	nitrite transmembrane transporter activity
FGE25_RS18190	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
FGE25_RS18195	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FGE25_RS18200	COG1845	cytochrome c oxidase, subunit III
FGE25_RS18205	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
FGE25_RS18210	COG0109	protoheme IX farnesyltransferase activity
FGE25_RS18215	COG2814	Major facilitator Superfamily
FGE25_RS18225	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
FGE25_RS18245	COG0142	geranyltranstransferase activity
FGE25_RS18255	COG0667	Aldo Keto reductase
FGE25_RS18260	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
FGE25_RS18270	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FGE25_RS18280	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FGE25_RS18280	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FGE25_RS18290	COG4238	major outer membrane lipoprotein
FGE25_RS18295	COG3248	Nucleoside-binding outer membrane protein
FGE25_RS18300	COG1438	arginine binding
FGE25_RS18310	COG1136	(ABC) transporter
FGE25_RS18310	COG0577	efflux transmembrane transporter activity
FGE25_RS18335	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FGE25_RS18335	COG2205	protein histidine kinase activity
FGE25_RS18345	COG2197	response regulator
FGE25_RS18350	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FGE25_RS18360	COG1862	Preprotein translocase
FGE25_RS18370	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
FGE25_RS18375	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
FGE25_RS18380	COG0450	alkyl hydroperoxide reductase
FGE25_RS18395	COG0366	Alpha amylase catalytic
FGE25_RS18405	COG1114	Component of the transport system for branched-chain amino acids
FGE25_RS18410	COG5002	protein histidine kinase activity
FGE25_RS18420	COG0420	3'-5' exonuclease activity
FGE25_RS18425	COG0419	ATPase involved in DNA repair
FGE25_RS18430	COG1940	carbohydrate kinase activity
FGE25_RS18440	COG3123	guanosine phosphorylase activity
FGE25_RS18445	COG4126	flavin adenine dinucleotide binding
FGE25_RS18455	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
FGE25_RS18465	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FGE25_RS18480	COG1785	Belongs to the alkaline phosphatase family
FGE25_RS18500	COG1181	Belongs to the D-alanine--D-alanine ligase family
FGE25_RS18520	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
FGE25_RS18530	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FGE25_RS18535	COG0113	porphobilinogen synthase activity
FGE25_RS18555	COG4303	Ethanolamine ammonia lyase large subunit
FGE25_RS18570	COG2323	membrane
FGE25_RS18575	COG1546	Belongs to the CinA family
FGE25_RS18590	COG0583	DNA-binding transcription factor activity
FGE25_RS18595	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
FGE25_RS18605	COG3729	General stress protein
FGE25_RS18615	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
FGE25_RS18620	COG1971	Probably functions as a manganese efflux pump
FGE25_RS18625	COG3443	Belongs to the bacterial solute-binding protein 9 family
FGE25_RS18630	COG3121	Chaperone
FGE25_RS18640	COG3188	usher protein
FGE25_RS18655	COG1309	transcriptional regulator
FGE25_RS18675	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
FGE25_RS18700	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
FGE25_RS18710	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
FGE25_RS18730	COG2195	Cleaves the N-terminal amino acid of tripeptides
FGE25_RS18740	COG3034	peptidoglycan biosynthetic process
FGE25_RS18745	COG0121	glutamine amidotransferase
FGE25_RS18760	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FGE25_RS18785	COG4608	Belongs to the ABC transporter superfamily
FGE25_RS18790	COG0444	Belongs to the ABC transporter superfamily
FGE25_RS18805	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
FGE25_RS18840	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FGE25_RS18850	COG0720	synthase
FGE25_RS18855	COG1028	Short-chain dehydrogenase reductase Sdr
FGE25_RS18860	COG0602	queuosine metabolic process
FGE25_RS18865	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
FGE25_RS18885	COG3956	TIGRFAM MazG family protein
FGE25_RS18890	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FGE25_RS18895	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FGE25_RS18900	COG2205	protein histidine kinase activity
FGE25_RS18900	COG4999	Histidine kinase
FGE25_RS18900	COG3437	response regulator, receiver
FGE25_RS18900	COG3850	Histidine kinase
FGE25_RS18905	COG1929	Belongs to the glycerate kinase type-1 family
FGE25_RS18910	COG4948	Mandelate Racemase Muconate Lactonizing
FGE25_RS18915	COG4948	Mandelate Racemase Muconate Lactonizing
FGE25_RS18920	COG2271	Major facilitator Superfamily
FGE25_RS18925	COG0716	FMN binding
FGE25_RS18930	COG0564	pseudouridine synthase activity
FGE25_RS18935	COG3098	single-species biofilm formation
FGE25_RS18950	COG1611	Belongs to the LOG family
FGE25_RS18955	COG0814	amino acid
FGE25_RS18960	COG1760	l-serine dehydratase
FGE25_RS18985	COG1953	Uracil, thiamine, allantoin
FGE25_RS18995	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FGE25_RS19005	COG2226	methyltransferase
FGE25_RS19015	COG0741	lytic transglycosylase activity
FGE25_RS19015	COG1388	LysM domain
FGE25_RS19020	COG3021	interspecies interaction between organisms
FGE25_RS19025	COG0583	DNA-binding transcription factor activity
FGE25_RS19050	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FGE25_RS19080	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
FGE25_RS19085	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FGE25_RS19090	COG2011	ABC-type metal ion transport system permease component
FGE25_RS19095	COG1464	Belongs to the NlpA lipoprotein family
FGE25_RS19105	COG1720	tRNA m6t6A37 methyltransferase activity
FGE25_RS19115	COG3015	lipoprotein NlpE involved in copper resistance
FGE25_RS19120	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
FGE25_RS19125	COG4681	YaeQ
FGE25_RS19135	COG4568	rho-dependent transcription termination
FGE25_RS19140	COG0037	tRNA processing
FGE25_RS19145	COG0346	lactoylglutathione lyase activity
FGE25_RS19180	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FGE25_RS19185	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FGE25_RS19190	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
FGE25_RS19195	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FGE25_RS19205	COG0575	Belongs to the CDS family
FGE25_RS19215	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
FGE25_RS19230	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
FGE25_RS19240	COG0024	Methionine aminopeptidase
FGE25_RS19260	COG3835	regulator
FGE25_RS19265	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FGE25_RS19285	COG2860	membrane
FGE25_RS19305	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FGE25_RS19310	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FGE25_RS19315	COG1120	ATPase activity
FGE25_RS19320	COG4774	siderophore transport
FGE25_RS19325	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FGE25_RS19330	COG1643	Atp-dependent helicase
FGE25_RS19335	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
FGE25_RS19340	COG1489	DNA binding
FGE25_RS19345	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
FGE25_RS19355	COG0617	tRNA 3'-terminal CCA addition
FGE25_RS19360	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
FGE25_RS19365	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
FGE25_RS19370	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
FGE25_RS19380	COG0726	polysaccharide deacetylase
FGE25_RS19385	COG0842	Transport permease protein
FGE25_RS19390	COG1131	(ABC) transporter
FGE25_RS19395	COG0288	reversible hydration of carbon dioxide
FGE25_RS19405	COG4993	Dehydrogenase
FGE25_RS19410	COG2132	Multicopper oxidase
FGE25_RS19450	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FGE25_RS19455	COG0508	dehydrogenase complex catalyzes the overall conversion of
FGE25_RS19460	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
FGE25_RS19465	COG2186	Transcriptional regulator
FGE25_RS19470	COG1113	amino acid transport
FGE25_RS19475	COG2211	Major facilitator Superfamily
FGE25_RS19480	COG3940	Belongs to the glycosyl hydrolase 43 family
FGE25_RS19485	COG3725	Membrane protein required for beta-lactamase induction
FGE25_RS19500	COG4969	Belongs to the N-Me-Phe pilin family
FGE25_RS19505	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FGE25_RS19510	COG1459	type II secretion system
FGE25_RS19535	COG0494	nUDIX hydrolase
FGE25_RS19555	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
FGE25_RS19560	COG0849	cell division
FGE25_RS19570	COG1181	Belongs to the D-alanine--D-alanine ligase family
FGE25_RS19585	COG0772	Belongs to the SEDS family
FGE25_RS19595	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FGE25_RS19600	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
FGE25_RS19605	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
FGE25_RS19610	COG0768	penicillin binding
FGE25_RS19630	COG1609	Transcriptional regulator
FGE25_RS19640	COG0028	Belongs to the TPP enzyme family
FGE25_RS19675	COG2814	Major facilitator Superfamily
FGE25_RS19690	COG4143	(ABC) transporter
FGE25_RS19695	COG1178	ABC-type Fe3 transport system permease component
FGE25_RS19705	COG0586	Pfam SNARE associated Golgi protein
FGE25_RS19720	COG2160	L-arabinose isomerase activity
FGE25_RS19725	COG0235	Class ii aldolase
FGE25_RS19730	COG0417	DNA replication proofreading
FGE25_RS19735	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
FGE25_RS19740	COG0564	pseudouridine synthase activity
FGE25_RS19750	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
FGE25_RS19775	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
FGE25_RS19805	COG0505	Belongs to the CarA family
FGE25_RS19815	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
FGE25_RS19830	COG1047	Peptidyl-prolyl cis-trans
FGE25_RS19845	COG0196	riboflavin kinase activity
FGE25_RS19855	COG0268	Binds directly to 16S ribosomal RNA
FGE25_RS19860	COG0583	DNA-binding transcription factor activity
FGE25_RS19880	COG1584	GPR1 FUN34 yaaH family protein
FGE25_RS19890	COG0521	Mo-molybdopterin cofactor biosynthetic process
FGE25_RS19895	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
FGE25_RS19900	COG1115	amino acid carrier protein
FGE25_RS19905	COG3022	response to hydroperoxide
FGE25_RS19910	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
FGE25_RS19920	COG0527	aspartate kinase activity
FGE25_RS19920	COG0460	homoserine dehydrogenase
FGE25_RS19930	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
FGE25_RS19940	COG0745	RESPONSE REGULATOR receiver
FGE25_RS19945	COG4452	Inner membrane protein CreD
FGE25_RS19950	COG2205	protein histidine kinase activity
FGE25_RS19955	COG0745	RESPONSE REGULATOR receiver
FGE25_RS19960	COG3045	CreA protein
FGE25_RS19965	COG2207	Transcriptional regulator
FGE25_RS19965	COG3708	Transcriptional regulator
FGE25_RS19980	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
FGE25_RS19985	COG0741	lytic transglycosylase activity
FGE25_RS19990	COG0488	(ABC) transporter
FGE25_RS20010	COG0560	Phosphoserine phosphatase
FGE25_RS20015	COG3726	membrane protein affecting hemolysin expression
FGE25_RS20025	COG3550	peptidyl-serine autophosphorylation
FGE25_RS20050	COG1328	CTP reductase activity
FGE25_RS20055	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
FGE25_RS20060	COG0084	hydrolase, TatD family'
FGE25_RS20065	COG4667	esterase of the alpha-beta hydrolase superfamily
FGE25_RS20075	COG2823	Periplasmic or secreted lipoprotein
FGE25_RS20085	COG1011	Hydrolase
FGE25_RS20090	COG0456	acetyltransferase
FGE25_RS20095	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
FGE25_RS20125	COG3706	GGDEF domain
FGE25_RS20130	COG4114	ferric iron reductase
FGE25_RS20135	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FGE25_RS20140	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
FGE25_RS20145	COG2197	response regulator
FGE25_RS20150	COG2197	response regulator
FGE25_RS20155	COG2966	Psort location CytoplasmicMembrane, score
FGE25_RS20165	COG1846	Transcriptional regulator
FGE25_RS20170	COG1764	response to oxidative stress
FGE25_RS20180	COG1484	DNA-dependent DNA replication
FGE25_RS20200	COG0840	transmembrane signaling receptor activity
FGE25_RS20205	COG1966	Carbon starvation protein
FGE25_RS20210	COG2879	small protein
FGE25_RS20215	COG0523	cobalamin synthesis protein
FGE25_RS20220	COG1012	belongs to the aldehyde dehydrogenase family
FGE25_RS20235	COG1473	amidohydrolase
FGE25_RS20240	COG0700	Nucleoside recognition
FGE25_RS20245	COG3366	ferrous iron transmembrane transporter activity
FGE25_RS20250	COG0583	DNA-binding transcription factor activity
FGE25_RS20255	COG2207	Transcriptional regulator
FGE25_RS20255	COG1917	Cupin 2, conserved barrel domain protein
FGE25_RS20265	COG2733	membrane
FGE25_RS20275	COG1775	2-hydroxyglutaryl-CoA dehydratase, D-component
FGE25_RS20280	COG1924	4 iron, 4 sulfur cluster binding
FGE25_RS20315	COG0740	serine-type endopeptidase activity
FGE25_RS20320	COG5457	Domain of unknown function (DUF1127)
FGE25_RS20325	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FGE25_RS20330	COG0791	NLP P60 protein
FGE25_RS20335	COG1191	sigma factor activity
FGE25_RS20340	COG0745	RESPONSE REGULATOR receiver
FGE25_RS20355	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
FGE25_RS20360	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FGE25_RS20360	COG1263	PTS System
FGE25_RS20375	COG0583	DNA-binding transcription factor activity
FGE25_RS20380	COG2249	NAD(P)H dehydrogenase (quinone) activity
FGE25_RS20385	COG1309	transcriptional regulator
FGE25_RS20400	COG1538	Outer membrane efflux protein
FGE25_RS20410	COG1737	Transcriptional regulator
FGE25_RS20420	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FGE25_RS20425	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FGE25_RS20430	COG1120	ATPase activity
FGE25_RS20435	COG4774	siderophore transport
FGE25_RS20445	COG0395	ABC-type sugar transport system, permease component
FGE25_RS20450	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
FGE25_RS20455	COG3842	ATPase activity
FGE25_RS20460	COG1653	transport
FGE25_RS20515	COG2259	Doxx family
FGE25_RS20540	COG0583	DNA-binding transcription factor activity
FGE25_RS20625	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
FGE25_RS20645	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
FGE25_RS20665	COG1715	Restriction endonuclease
FGE25_RS20675	COG0582	viral genome integration into host DNA
FGE25_RS20685	COG2197	response regulator
FGE25_RS20730	COG1064	alcohol dehydrogenase
FGE25_RS20745	COG0795	lipopolysaccharide-transporting ATPase activity
FGE25_RS20750	COG0795	lipopolysaccharide-transporting ATPase activity
FGE25_RS20755	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
FGE25_RS20760	COG2927	DNA polymerase III (CHI subunit)
FGE25_RS20765	COG0525	valine-tRNA ligase activity
FGE25_RS20785	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
FGE25_RS20795	COG2731	YhcH YjgK YiaL family protein
FGE25_RS20800	COG2235	arginine
FGE25_RS20815	COG1288	antiporter activity
FGE25_RS20820	COG1438	arginine binding
FGE25_RS20845	COG0251	oxidation-reduction process
FGE25_RS20850	COG3525	Glycosyl hydrolase, family 20, catalytic domain
FGE25_RS20870	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FGE25_RS20870	COG1263	PTS System
FGE25_RS20875	COG0366	Alpha amylase catalytic
FGE25_RS20885	COG0602	queuosine metabolic process
FGE25_RS20890	COG2207	Transcriptional regulator
FGE25_RS20895	COG0300	oxidoreductase activity
FGE25_RS20900	COG3711	transcriptional antiterminator
FGE25_RS20900	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FGE25_RS20920	COG3964	amidohydrolase
FGE25_RS20950	COG0583	DNA-binding transcription factor activity
FGE25_RS20955	COG1028	Short-chain dehydrogenase reductase Sdr
FGE25_RS20955	COG0604	alcohol dehydrogenase
FGE25_RS20955	COG3321	synthase
FGE25_RS20960	COG3783	Cytochrome b(562)
FGE25_RS20965	COG0312	modulator of DNA gyrase
FGE25_RS20980	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FGE25_RS20995	COG0840	transmembrane signaling receptor activity
FGE25_RS21000	COG1172	Belongs to the binding-protein-dependent transport system permease family
FGE25_RS21005	COG1172	Belongs to the binding-protein-dependent transport system permease family
FGE25_RS21010	COG1129	ABC transporter
FGE25_RS21015	COG1879	ABC-type sugar transport system periplasmic component
FGE25_RS21020	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
FGE25_RS21030	COG2105	PFAM AIG2 family protein
FGE25_RS21035	COG2911	Protein conserved in bacteria
FGE25_RS21040	COG0729	surface antigen
FGE25_RS21045	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FGE25_RS21050	COG1253	flavin adenine dinucleotide binding
FGE25_RS21060	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
FGE25_RS21065	COG1218	3'(2'),5'-bisphosphate nucleotidase
FGE25_RS21075	COG1733	regulation of RNA biosynthetic process
FGE25_RS21080	COG0702	epimerase
FGE25_RS21090	COG0697	spore germination
FGE25_RS21095	COG0840	transmembrane signaling receptor activity
FGE25_RS21105	COG1113	amino acid transport
FGE25_RS21110	COG0545	Peptidyl-prolyl cis-trans isomerase
FGE25_RS21115	COG3061	Opacity-associated protein A
FGE25_RS21120	COG0697	spore germination
FGE25_RS21155	COG1073	alpha beta
FGE25_RS21160	COG3650	response to hydrogen peroxide
FGE25_RS21175	COG1960	acyl-CoA dehydrogenase activity
FGE25_RS21180	COG0477	Major facilitator Superfamily
FGE25_RS21185	COG0754	glutathionylspermidine amidase activity
FGE25_RS21190	COG5463	Belongs to the UPF0441 family
FGE25_RS21195	COG3766	membrane
FGE25_RS21205	COG1842	Phage shock protein A
FGE25_RS21210	COG3789	protein conserved in bacteria
FGE25_RS21215	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FGE25_RS21220	COG0557	exoribonuclease II activity
FGE25_RS21225	COG1959	2 iron, 2 sulfur cluster binding
FGE25_RS21235	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
FGE25_RS21240	COG0330	HflC and HflK could
FGE25_RS21245	COG0330	HflC and HflK could
FGE25_RS21250	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
FGE25_RS21260	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
FGE25_RS21265	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
FGE25_RS21270	COG0860	N-Acetylmuramoyl-L-alanine amidase
FGE25_RS21275	COG0802	atpase or kinase
FGE25_RS21280	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
FGE25_RS21280	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
FGE25_RS21285	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
FGE25_RS21320	COG1511	domain protein
FGE25_RS21320	COG3264	Mechanosensitive ion channel
FGE25_RS21330	COG1053	succinate dehydrogenase
FGE25_RS21335	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
FGE25_RS21340	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
FGE25_RS21355	COG2076	Multidrug Resistance protein
FGE25_RS21365	COG5510	response to toxic substance
FGE25_RS21380	COG1509	lysine 2,3-aminomutase activity
FGE25_RS21410	COG0531	amino acid
FGE25_RS21415	COG3030	protein affecting phage T7 exclusion by the F plasmid
FGE25_RS21420	COG1027	Aspartate ammonia-lyase
FGE25_RS21425	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
FGE25_RS21440	COG1309	transcriptional regulator
FGE25_RS21460	COG3647	Membrane
FGE25_RS21465	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
FGE25_RS21490	COG2824	Alkylphosphonate utilization operon protein PhnA
FGE25_RS21495	COG2764	glyoxalase bleomycin resistance protein dioxygenase
FGE25_RS21500	COG2188	Transcriptional regulator
FGE25_RS21505	COG3624	Phosphonate C-P lyase system protein PhnG
FGE25_RS21510	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
FGE25_RS21515	COG3626	phosphonate metabolism
FGE25_RS21520	COG3627	carbon phosphorus lyase activity
FGE25_RS21525	COG4107	phosphonate C-P lyase system protein PhnK
FGE25_RS21530	COG4778	phosphonate C-P lyase system protein PhnL
FGE25_RS21535	COG3454	Phosphonate metabolism
FGE25_RS21545	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
FGE25_RS21565	COG1129	ABC transporter
FGE25_RS21570	COG1172	Belongs to the binding-protein-dependent transport system permease family
FGE25_RS21575	COG1879	ABC-type sugar transport system periplasmic component
FGE25_RS21585	COG0191	fructose-bisphosphate aldolase activity
FGE25_RS21590	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FGE25_RS21595	COG0745	RESPONSE REGULATOR receiver
FGE25_RS21610	COG4106	trans-aconitate 2-methyltransferase activity
FGE25_RS21615	COG0697	spore germination
FGE25_RS21625	COG0640	Transcriptional regulator
FGE25_RS21630	COG1301	dicarboxylic acid transport
FGE25_RS21640	COG3162	membrane
FGE25_RS21645	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FGE25_RS21650	COG0673	inositol 2-dehydrogenase activity
FGE25_RS21655	COG1346	cytolysis
FGE25_RS21660	COG1380	Effector of murein hydrolase LrgA
FGE25_RS21665	COG0583	DNA-binding transcription factor activity
FGE25_RS21670	COG0025	NhaP-type Na H and K H
FGE25_RS21675	COG2252	PERMEase
FGE25_RS21685	COG0789	Transcriptional regulator
FGE25_RS21695	COG4943	cyclic-guanylate-specific phosphodiesterase activity
FGE25_RS21730	COG3842	ATPase activity
FGE25_RS21735	COG1234	tRNA 3'-trailer cleavage
FGE25_RS21740	COG1609	Transcriptional regulator
FGE25_RS21745	COG0483	inositol monophosphate 1-phosphatase activity
FGE25_RS21765	COG3209	COG3209 Rhs family protein
FGE25_RS21780	COG3501	Rhs element vgr protein
FGE25_RS21785	COG0765	amino acid transport
FGE25_RS21790	COG1126	abc transporter atp-binding protein
FGE25_RS21795	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FGE25_RS21805	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
FGE25_RS21810	COG2315	Protein conserved in bacteria
FGE25_RS21815	COG0745	RESPONSE REGULATOR receiver
FGE25_RS21825	COG0432	Pfam Uncharacterised protein family UPF0047
FGE25_RS21830	COG3700	Belongs to the class B bacterial acid phosphatase family
FGE25_RS21835	COG1448	Aminotransferase
FGE25_RS21850	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FGE25_RS21855	COG0305	Participates in initiation and elongation during chromosome replication
FGE25_RS21870	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FGE25_RS21875	COG1335	isochorismatase
FGE25_RS21885	COG0735	belongs to the Fur family
FGE25_RS21890	COG3237	CsbD-like
FGE25_RS21895	COG0534	Mate efflux family protein
FGE25_RS21905	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
FGE25_RS21930	COG4580	involved in the transport of maltose and maltodextrins
FGE25_RS21940	COG2182	Extracellular solute-binding protein
FGE25_RS21955	COG3223	Belongs to the PsiE family
FGE25_RS21965	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
FGE25_RS21970	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FGE25_RS21995	COG0527	aspartate kinase activity
FGE25_RS22000	COG3541	Predicted nucleotidyltransferase
FGE25_RS22005	COG1690	Belongs to the RtcB family
FGE25_RS22015	COG4650	regulator
FGE25_RS22025	COG5499	transcription regulator containing HTH domain
FGE25_RS22030	COG4680	protein conserved in bacteria
FGE25_RS22040	COG1187	pseudouridine synthase activity
FGE25_RS22045	COG1283	sodium-dependent phosphate transmembrane transporter activity
FGE25_RS22070	COG1414	Transcriptional regulator
FGE25_RS22085	COG4589	Belongs to the CDS family
FGE25_RS22100	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
FGE25_RS22140	COG0151	Belongs to the GarS family
FGE25_RS22150	COG0776	regulation of translation
FGE25_RS22155	COG3068	Protein conserved in bacteria
FGE25_RS22175	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
FGE25_RS22185	COG0352	thiamine-phosphate diphosphorylase activity
FGE25_RS22190	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FGE25_RS22195	COG2104	thiamine diphosphate biosynthetic process
FGE25_RS22205	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
FGE25_RS22210	COG3706	GGDEF domain
FGE25_RS22220	COG1447	Phosphotransferase system cellobiose-specific component IIA
FGE25_RS22240	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
FGE25_RS22255	COG0250	Participates in transcription elongation, termination and antitermination
FGE25_RS22260	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FGE25_RS22305	COG0812	UDP-N-acetylmuramate dehydrogenase activity
FGE25_RS22345	COG1739	Uncharacterized protein family UPF0029
FGE25_RS22380	COG0084	hydrolase, TatD family'
FGE25_RS22385	COG0805	protein transport
FGE25_RS22395	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FGE25_RS22405	COG3165	ubiquinone biosynthetic process from chorismate
FGE25_RS22415	COG1322	Protein conserved in bacteria
FGE25_RS22425	COG0412	Dienelactone hydrolase
FGE25_RS22430	COG3842	ATPase activity
FGE25_RS22435	COG4149	molybdate abc transporter
FGE25_RS22440	COG1840	ABC-type Fe3 transport system, periplasmic component
FGE25_RS22450	COG0583	DNA-binding transcription factor activity
FGE25_RS22455	COG0697	spore germination
FGE25_RS22460	COG0561	phosphatase activity
FGE25_RS22465	COG2267	carboxylic ester hydrolase activity
FGE25_RS22470	COG1280	lysine exporter protein (LysE YggA)
FGE25_RS22475	COG1280	lysine exporter protein (LysE YggA)
FGE25_RS22485	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
FGE25_RS22490	COG2050	protein possibly involved in aromatic compounds catabolism
FGE25_RS22510	COG0598	Magnesium transport protein CorA
FGE25_RS22515	COG0210	DNA helicase
FGE25_RS22520	COG1011	Hydrolase
FGE25_RS22540	COG5567	small periplasmic lipoprotein
FGE25_RS22550	COG3072	Adenylate cyclase
FGE25_RS22555	COG0181	hydroxymethylbilane synthase activity
FGE25_RS22565	COG2959	enzyme of heme biosynthesis
FGE25_RS22570	COG3071	HemY protein
FGE25_RS22595	COG1113	amino acid transport
FGE25_RS22615	COG2244	polysaccharide biosynthetic process
FGE25_RS22620	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
FGE25_RS22625	COG0456	acetyltransferase
FGE25_RS22630	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
FGE25_RS22635	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
FGE25_RS22645	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FGE25_RS22650	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
FGE25_RS22655	COG3118	belongs to the thioredoxin family
FGE25_RS22675	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FGE25_RS22695	COG0583	DNA-binding transcription factor activity
FGE25_RS22700	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FGE25_RS22710	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FGE25_RS22715	COG3978	acetolactate synthase activity
FGE25_RS22730	COG0606	chelatase, subunit chli
FGE25_RS22735	COG3085	chromosome segregation
FGE25_RS22815	COG0583	DNA-binding transcription factor activity
FGE25_RS22820	COG0165	Argininosuccinate lyase
FGE25_RS22845	COG2207	Transcriptional regulator
FGE25_RS22855	COG0371	Dehydrogenase
FGE25_RS22860	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
FGE25_RS22865	COG0460	homoserine dehydrogenase
FGE25_RS22865	COG0527	aspartate kinase activity
FGE25_RS22870	COG0626	cystathionine gamma-synthase activity
FGE25_RS22885	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
FGE25_RS22890	COG1609	Transcriptional regulator
FGE25_RS22895	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
FGE25_RS22910	COG1575	Belongs to the MenA family. Type 1 subfamily
FGE25_RS22915	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FGE25_RS22920	COG3074	FtsZ-dependent cytokinesis
FGE25_RS22925	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
FGE25_RS22935	COG1494	fructose-1,6-bisphosphatase
FGE25_RS22945	COG3152	Membrane
FGE25_RS22955	COG0149	triose-phosphate isomerase activity
FGE25_RS23020	COG1598	PFAM Uncharacterised protein family UPF0150
FGE25_RS23095	COG0582	viral genome integration into host DNA
FGE25_RS23100	COG3678	ATP-independent chaperone mediated protein folding
FGE25_RS23105	COG0745	RESPONSE REGULATOR receiver
FGE25_RS23110	COG2205	protein histidine kinase activity
FGE25_RS23115	COG2258	MOSC domain
FGE25_RS23140	COG4977	sequence-specific DNA binding
FGE25_RS23140	COG1917	Cupin 2, conserved barrel domain protein
FGE25_RS23150	COG1070	Carbohydrate kinase
FGE25_RS23165	COG1879	ABC-type sugar transport system periplasmic component
FGE25_RS23170	COG1129	ABC transporter
FGE25_RS23175	COG1172	Belongs to the binding-protein-dependent transport system permease family
FGE25_RS23185	COG1454	alcohol dehydrogenase
FGE25_RS23200	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
FGE25_RS23220	COG0577	efflux transmembrane transporter activity
FGE25_RS23220	COG1136	(ABC) transporter
FGE25_RS23265	COG0437	4 iron, 4 sulfur cluster binding
FGE25_RS23270	COG2864	formate dehydrogenase
FGE25_RS23290	COG0456	acetyltransferase
FGE25_RS23305	COG1011	Hydrolase
FGE25_RS23315	COG0174	glutamine synthetase
FGE25_RS23320	COG3852	Histidine kinase
FGE25_RS23335	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FGE25_RS23355	COG0204	Acyl-transferase
FGE25_RS23365	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
FGE25_RS23370	COG3084	Protein conserved in bacteria
FGE25_RS23375	COG0746	molybdenum cofactor guanylyltransferase activity
FGE25_RS23380	COG1763	Mo-molybdopterin cofactor biosynthetic process
FGE25_RS23405	COG2186	Transcriptional regulator
FGE25_RS23410	COG0477	Major facilitator Superfamily
FGE25_RS23415	COG1609	Transcriptional regulator
FGE25_RS23420	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FGE25_RS23425	COG1879	ABC-type sugar transport system periplasmic component
FGE25_RS23430	COG1172	Belongs to the binding-protein-dependent transport system permease family
FGE25_RS23440	COG1869	D-ribose catabolic process
FGE25_RS23465	COG1522	sequence-specific DNA binding
FGE25_RS23470	COG0716	FMN binding
FGE25_RS23485	COG3312	ion transport
FGE25_RS23500	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
FGE25_RS23510	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
FGE25_RS23520	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
FGE25_RS23525	COG0355	proton-transporting ATP synthase activity, rotational mechanism
FGE25_RS23535	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
FGE25_RS23550	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
FGE25_RS23555	COG0573	inorganic phosphate transmembrane transporter activity
FGE25_RS23560	COG0581	inorganic phosphate transmembrane transporter activity
FGE25_RS23570	COG0704	Plays a role in the regulation of phosphate uptake
FGE25_RS23575	COG1397	ADP-ribosylglycohydrolase
FGE25_RS23580	COG3196	Protein conserved in bacteria
FGE25_RS23585	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FGE25_RS23590	COG2252	PERMEase
FGE25_RS23595	COG0431	NADPH-dependent FMN reductase
FGE25_RS23600	COG2091	lysine biosynthetic process via aminoadipic acid