locus-tag	class	description
D0638_RS00010	COG0592	DNA-directed DNA polymerase activity
D0638_RS00020	COG2501	S4 domain
D0638_RS00035	COG0187	DNA topoisomerase II activity
D0638_RS00045	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
D0638_RS00060	COG0629	single-stranded DNA binding
D0638_RS00070	COG1271	oxidase subunit
D0638_RS00075	COG1294	oxidase, subunit
D0638_RS00135	COG0561	phosphatase activity
D0638_RS00155	COG3409	Peptidoglycan-binding domain 1 protein
D0638_RS00230	COG3409	Peptidoglycan-binding domain 1 protein
D0638_RS00265	COG0800	Aldolase
D0638_RS00290	COG1132	(ABC) transporter
D0638_RS00295	COG2814	Major facilitator Superfamily
D0638_RS00305	COG2409	Drug exporters of the RND superfamily
D0638_RS00305	COG1033	growth of symbiont in host cell
D0638_RS00310	COG1309	transcriptional regulator
D0638_RS00325	COG1732	Glycine betaine
D0638_RS00360	COG2217	Heavy metal translocating P-type atpase
D0638_RS00365	COG2217	Heavy metal translocating P-type atpase
D0638_RS00375	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
D0638_RS00385	COG0159	tryptophan synthase activity
D0638_RS00395	COG0135	phosphoribosylanthranilate isomerase activity
D0638_RS00430	COG2814	Major facilitator Superfamily
D0638_RS00475	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
D0638_RS00495	COG0019	diaminopimelate decarboxylase activity
D0638_RS00500	COG0527	aspartate kinase activity
D0638_RS00510	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
D0638_RS00565	COG1131	(ABC) transporter
D0638_RS00580	COG0305	Participates in initiation and elongation during chromosome replication
D0638_RS00595	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
D0638_RS00600	COG1737	Transcriptional regulator
D0638_RS00605	COG1309	transcriptional regulator
D0638_RS00610	COG0577	efflux transmembrane transporter activity
D0638_RS00610	COG1136	(ABC) transporter
D0638_RS00630	COG2217	Heavy metal translocating P-type atpase
D0638_RS00635	COG0640	Transcriptional regulator
D0638_RS00640	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
D0638_RS00645	COG0583	DNA-binding transcription factor activity
D0638_RS00650	COG3620	sequence-specific DNA binding
D0638_RS00660	COG1131	(ABC) transporter
D0638_RS00670	COG1328	CTP reductase activity
D0638_RS00750	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
D0638_RS00790	COG2252	PERMEase
D0638_RS00805	COG1116	anion transmembrane transporter activity
D0638_RS00810	COG4521	taurine ABC transporter
D0638_RS00815	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
D0638_RS00820	COG0446	pyridine nucleotide-disulphide oxidoreductase
D0638_RS00825	COG2391	methyltransferase activity
D0638_RS00840	COG0346	lactoylglutathione lyase activity
D0638_RS00900	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
D0638_RS00925	COG1511	domain protein
D0638_RS00925	COG1511	domain protein
D0638_RS00935	COG0477	Major facilitator Superfamily
D0638_RS00945	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
D0638_RS00950	COG4166	transmembrane transport
D0638_RS00970	COG1131	(ABC) transporter
D0638_RS00995	COG1132	(ABC) transporter
D0638_RS01000	COG1396	sequence-specific DNA binding
D0638_RS01015	COG0446	pyridine nucleotide-disulphide oxidoreductase
D0638_RS01055	COG0716	FMN binding
D0638_RS01070	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
D0638_RS01080	COG2261	transglycosylase associated protein
D0638_RS01095	COG1302	Protein conserved in bacteria
D0638_RS01125	COG3442	glutamine amidotransferase
D0638_RS01145	COG1192	Involved in chromosome partitioning
D0638_RS01150	COG1475	DNA binding
D0638_RS01155	COG4481	Protein conserved in bacteria
D0638_RS01160	COG0012	GTP binding
D0638_RS01170	COG0517	IMP dehydrogenase activity
D0638_RS01170	COG0516	GMP reductase activity
D0638_RS01190	COG1686	Belongs to the peptidase S11 family
D0638_RS01195	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
D0638_RS01205	COG1794	racemase activity, acting on amino acids and derivatives
D0638_RS01210	COG0656	L-ascorbic acid biosynthetic process
D0638_RS01215	COG1349	DNA-binding transcription factor activity
D0638_RS01225	COG1012	belongs to the aldehyde dehydrogenase family
D0638_RS01230	COG3718	enzyme involved in inositol metabolism
D0638_RS01235	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
D0638_RS01240	COG3962	Belongs to the TPP enzyme family
D0638_RS01245	COG0673	inositol 2-dehydrogenase activity
D0638_RS01250	COG0673	inositol 2-dehydrogenase activity
D0638_RS01260	COG0191	fructose-bisphosphate aldolase activity
D0638_RS01265	COG1942	4-Oxalocrotonate Tautomerase
D0638_RS01270	COG1737	Transcriptional regulator
D0638_RS01275	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
D0638_RS01285	COG2610	gluconate transmembrane transporter activity
D0638_RS01295	COG1121	(ABC) transporter
D0638_RS01310	COG2084	Dehydrogenase
D0638_RS01315	COG1164	Oligoendopeptidase f
D0638_RS01320	COG1316	TRANSCRIPTIONal
D0638_RS01325	COG1114	Component of the transport system for branched-chain amino acids
D0638_RS01340	COG1216	Glycosyl transferase, family 2
D0638_RS01365	COG0488	(ABC) transporter
D0638_RS01390	COG3118	belongs to the thioredoxin family
D0638_RS01410	COG0683	leucine binding
D0638_RS01440	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
D0638_RS01450	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
D0638_RS01455	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
D0638_RS01480	COG2723	6-phospho-beta-galactosidase activity
D0638_RS01485	COG0446	pyridine nucleotide-disulphide oxidoreductase
D0638_RS01505	COG2182	Extracellular solute-binding protein
D0638_RS01515	COG3064	Membrane
D0638_RS01515	COG3525	Glycosyl hydrolase, family 20, catalytic domain
D0638_RS01515	COG3583	domain protein
D0638_RS01520	COG1482	cell wall glycoprotein biosynthetic process
D0638_RS01525	COG2188	Transcriptional regulator
D0638_RS01530	COG2222	sugar isomerase
D0638_RS01535	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
D0638_RS01550	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
D0638_RS01555	COG3715	PTS system
D0638_RS01560	COG3716	PTS system mannose fructose sorbose family IID component
D0638_RS01565	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
D0638_RS01565	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
D0638_RS01575	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
D0638_RS01580	COG0006	proline dipeptidase activity
D0638_RS01590	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
D0638_RS01595	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
D0638_RS01600	COG1447	Phosphotransferase system cellobiose-specific component IIA
D0638_RS01605	COG1363	Peptidase, m42
D0638_RS01615	COG2195	Cleaves the N-terminal amino acid of tripeptides
D0638_RS01620	COG4166	transmembrane transport
D0638_RS01645	COG1129	ABC transporter
D0638_RS01655	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
D0638_RS01675	COG0351	phosphomethylpyrimidine kinase
D0638_RS01680	COG0531	amino acid
D0638_RS01690	COG1609	Transcriptional regulator
D0638_RS01705	COG1172	Belongs to the binding-protein-dependent transport system permease family
D0638_RS01710	COG1879	ABC-type sugar transport system periplasmic component
D0638_RS01730	COG2814	Major facilitator Superfamily
D0638_RS01785	COG1131	(ABC) transporter
D0638_RS01805	COG1053	succinate dehydrogenase
D0638_RS01810	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
D0638_RS01870	COG2267	carboxylic ester hydrolase activity
D0638_RS01920	COG1609	Transcriptional regulator
D0638_RS01930	COG3716	PTS system mannose fructose sorbose family IID component
D0638_RS01970	COG3716	PTS system mannose fructose sorbose family IID component
D0638_RS01975	COG3715	PTS system
D0638_RS01980	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
D0638_RS01990	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
D0638_RS01990	COG3933	PFAM sigma-54 factor interaction domain-containing protein
D0638_RS01995	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
D0638_RS02000	COG3711	transcriptional antiterminator
D0638_RS02005	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
D0638_RS02005	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
D0638_RS02015	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
D0638_RS02015	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
D0638_RS02015	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
D0638_RS02020	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
D0638_RS02025	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
D0638_RS02025	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
D0638_RS02025	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
D0638_RS02045	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
D0638_RS02045	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
D0638_RS02045	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
D0638_RS02050	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
D0638_RS02050	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
D0638_RS02055	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
D0638_RS02070	COG0191	fructose-bisphosphate aldolase activity
D0638_RS02075	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
D0638_RS02075	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
D0638_RS02075	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
D0638_RS02080	COG1028	Short-chain dehydrogenase reductase Sdr
D0638_RS02090	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
D0638_RS02090	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
D0638_RS02095	COG3715	PTS system
D0638_RS02100	COG3716	PTS system mannose fructose sorbose family IID component
D0638_RS02105	COG0246	Mannitol dehydrogenase
D0638_RS02110	COG1461	Dihydroxyacetone kinase
D0638_RS02115	COG2376	Dihydroxyacetone kinase
D0638_RS02120	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
D0638_RS02125	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
D0638_RS02130	COG1609	Transcriptional regulator
D0638_RS02140	COG2390	Transcriptional regulator
D0638_RS02150	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
D0638_RS02155	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
D0638_RS02160	COG3715	PTS system
D0638_RS02165	COG3716	PTS system mannose fructose sorbose family IID component
D0638_RS02170	COG0191	fructose-bisphosphate aldolase activity
D0638_RS02175	COG0471	metal ion transport
D0638_RS02185	COG0583	DNA-binding transcription factor activity
D0638_RS02200	COG1122	ATPase activity
D0638_RS02250	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
D0638_RS02255	COG1349	DNA-binding transcription factor activity
D0638_RS02260	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
D0638_RS02265	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
D0638_RS02270	COG1349	DNA-binding transcription factor activity
D0638_RS02310	COG0477	Major facilitator Superfamily
D0638_RS02330	COG4221	oxidoreductase activity
D0638_RS02355	COG0446	pyridine nucleotide-disulphide oxidoreductase
D0638_RS02360	COG0561	phosphatase activity
D0638_RS02370	COG1609	Transcriptional regulator
D0638_RS02375	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
D0638_RS02385	COG3716	PTS system mannose fructose sorbose family IID component
D0638_RS02400	COG0366	Alpha amylase catalytic
D0638_RS02405	COG1132	(ABC) transporter
D0638_RS02410	COG1132	(ABC) transporter
D0638_RS02430	COG1464	Belongs to the NlpA lipoprotein family
D0638_RS02460	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
D0638_RS02465	COG1461	Dihydroxyacetone kinase
D0638_RS02470	COG2376	Dihydroxyacetone kinase
D0638_RS02495	COG2814	Major facilitator Superfamily
D0638_RS02515	COG0028	Belongs to the TPP enzyme family
D0638_RS02530	COG2226	methyltransferase
D0638_RS02535	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
D0638_RS02540	COG0174	glutamine synthetase
D0638_RS02555	COG0789	Transcriptional regulator
D0638_RS02560	COG0656	L-ascorbic acid biosynthetic process
D0638_RS02575	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
D0638_RS02600	COG1131	(ABC) transporter
D0638_RS02620	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
D0638_RS02650	COG0308	aminopeptidase N
D0638_RS02655	COG0531	amino acid
D0638_RS02675	COG1028	Short-chain dehydrogenase reductase Sdr
D0638_RS02685	COG2271	Major facilitator Superfamily
D0638_RS02690	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
D0638_RS02695	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
D0638_RS02700	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
D0638_RS02715	COG2801	Transposase and inactivated derivatives
D0638_RS02765	COG1396	sequence-specific DNA binding
D0638_RS02865	COG2826	transposase and inactivated derivatives, IS30 family
D0638_RS02900	COG2801	Transposase and inactivated derivatives
D0638_RS03050	COG3547	Transposase (IS116 IS110 IS902 family)
D0638_RS03080	COG3764	Sortase (surface protein transpeptidase)
D0638_RS03160	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
D0638_RS03190	COG0783	Belongs to the Dps family
D0638_RS03200	COG2801	Transposase and inactivated derivatives
D0638_RS03215	COG2801	Transposase and inactivated derivatives
D0638_RS03230	COG3976	FMN-binding domain protein
D0638_RS03230	COG0431	NADPH-dependent FMN reductase
D0638_RS03230	COG1053	succinate dehydrogenase
D0638_RS03270	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
D0638_RS03280	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
D0638_RS03325	COG1131	(ABC) transporter
D0638_RS03335	COG1309	transcriptional regulator
D0638_RS03355	COG4619	ABC transporter
D0638_RS03360	COG0390	transport system, permease component
D0638_RS03395	COG1174	glycine betaine transport
D0638_RS03405	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
D0638_RS03420	COG0626	cystathionine gamma-synthase activity
D0638_RS03425	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
D0638_RS03430	COG0765	amino acid transport
D0638_RS03440	COG1114	Component of the transport system for branched-chain amino acids
D0638_RS03490	COG0697	spore germination
D0638_RS03500	COG1131	(ABC) transporter
D0638_RS03515	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
D0638_RS03520	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
D0638_RS03530	COG1132	(ABC) transporter
D0638_RS03535	COG1132	(ABC) transporter
D0638_RS03540	COG2223	nitrite transmembrane transporter activity
D0638_RS03545	COG2188	Transcriptional regulator
D0638_RS03550	COG0366	Alpha amylase catalytic
D0638_RS03555	COG1263	PTS System
D0638_RS03555	COG2190	(PTS) system
D0638_RS03555	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
D0638_RS03565	COG0531	amino acid
D0638_RS03570	COG0039	L-malate dehydrogenase activity
D0638_RS03580	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
D0638_RS03585	COG1278	Cold shock
D0638_RS03600	COG0488	(ABC) transporter
D0638_RS03605	COG0702	epimerase
D0638_RS03615	COG0656	L-ascorbic acid biosynthetic process
D0638_RS03620	COG1113	amino acid transport
D0638_RS03630	COG0025	NhaP-type Na H and K H
D0638_RS03635	COG3547	Transposase (IS116 IS110 IS902 family)
D0638_RS03680	COG0004	ammonium transporteR
D0638_RS03690	COG1285	pathogenesis
D0638_RS03710	COG1131	(ABC) transporter
D0638_RS03720	COG0488	(ABC) transporter
D0638_RS03725	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
D0638_RS03730	COG1573	uracil-dna glycosylase
D0638_RS03745	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
D0638_RS03750	COG1215	transferase activity, transferring glycosyl groups
D0638_RS03760	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
D0638_RS03765	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
D0638_RS03770	COG1609	Transcriptional regulator
D0638_RS03775	COG2017	converts alpha-aldose to the beta-anomer
D0638_RS03800	COG3775	system Galactitol-specific IIC component
D0638_RS03820	COG3684	Belongs to the aldolase LacD family
D0638_RS03835	COG1349	DNA-binding transcription factor activity
D0638_RS03850	COG0419	ATPase involved in DNA repair
D0638_RS03880	COG1194	a g-specific adenine glycosylase
D0638_RS03890	COG2249	NAD(P)H dehydrogenase (quinone) activity
D0638_RS03910	COG0351	phosphomethylpyrimidine kinase
D0638_RS03925	COG2910	NAD(P)H-binding
D0638_RS03935	COG1472	Belongs to the glycosyl hydrolase 3 family
D0638_RS03960	COG4120	Belongs to the binding-protein-dependent transport system permease family
D0638_RS03970	COG0604	alcohol dehydrogenase
D0638_RS03980	COG0463	Glycosyl transferase, family 2
D0638_RS03985	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
D0638_RS03995	COG0745	RESPONSE REGULATOR receiver
D0638_RS04000	COG5002	protein histidine kinase activity
D0638_RS04010	COG2508	Transcriptional regulator
D0638_RS04025	COG0778	Nitroreductase
D0638_RS04065	COG0604	alcohol dehydrogenase
D0638_RS04080	COG0628	permease
D0638_RS04105	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
D0638_RS04120	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
D0638_RS04125	COG3189	MarR family transcriptional regulator
D0638_RS04155	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
D0638_RS04180	COG0300	oxidoreductase activity
D0638_RS04185	COG0105	UTP biosynthetic process
D0638_RS04190	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
D0638_RS04195	COG2267	carboxylic ester hydrolase activity
D0638_RS04225	COG2267	carboxylic ester hydrolase activity
D0638_RS04265	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
D0638_RS04295	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
D0638_RS04300	COG0343	queuine tRNA-ribosyltransferase activity
D0638_RS04305	COG1862	Preprotein translocase
D0638_RS04310	COG1012	belongs to the aldehyde dehydrogenase family
D0638_RS04310	COG1454	alcohol dehydrogenase
D0638_RS04325	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
D0638_RS04330	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
D0638_RS04340	COG4109	DRTGG domain
D0638_RS04345	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
D0638_RS04350	COG0513	Belongs to the DEAD box helicase family
D0638_RS04405	COG3118	belongs to the thioredoxin family
D0638_RS04420	COG1696	Membrane protein involved in D-alanine export
D0638_RS04430	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
D0638_RS04435	COG1719	4-vinyl reductase, 4VR
D0638_RS04440	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
D0638_RS04450	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
D0638_RS04465	COG0668	transmembrane transport
D0638_RS04485	COG1827	regulation of RNA biosynthetic process
D0638_RS04490	COG0006	proline dipeptidase activity
D0638_RS04495	COG1609	Transcriptional regulator
D0638_RS04500	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
D0638_RS04505	COG1011	Hydrolase
D0638_RS04545	COG0737	Belongs to the 5'-nucleotidase family
D0638_RS04550	COG4470	Protein conserved in bacteria
D0638_RS04555	COG0647	UMP catabolic process
D0638_RS04570	COG0586	Pfam SNARE associated Golgi protein
D0638_RS04575	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
D0638_RS04590	COG1098	S1 RNA binding domain
D0638_RS04740	COG0531	amino acid
D0638_RS04745	COG0438	transferase activity, transferring glycosyl groups
D0638_RS04750	COG0438	transferase activity, transferring glycosyl groups
D0638_RS04765	COG0436	Aminotransferase
D0638_RS04780	COG1368	sulfuric ester hydrolase activity
D0638_RS04785	COG0735	belongs to the Fur family
D0638_RS04830	COG0477	Major facilitator Superfamily
D0638_RS04840	COG2814	Major facilitator Superfamily
D0638_RS04850	COG0671	phosphoesterase, PA-phosphatase related
D0638_RS04870	COG2244	polysaccharide biosynthetic process
D0638_RS04875	COG1187	pseudouridine synthase activity
D0638_RS04885	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
D0638_RS04905	COG0438	transferase activity, transferring glycosyl groups
D0638_RS04910	COG0386	Belongs to the glutathione peroxidase family
D0638_RS04915	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
D0638_RS04925	COG3830	Belongs to the UPF0237 family
D0638_RS04950	COG2357	RelA SpoT domain protein
D0638_RS04960	COG0564	pseudouridine synthase activity
D0638_RS04970	COG3142	Participates in the control of copper homeostasis
D0638_RS04980	COG2706	6-phosphogluconolactonase activity
D0638_RS04990	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
D0638_RS05005	COG2226	methyltransferase
D0638_RS05015	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
D0638_RS05025	COG1674	ftsk spoiiie
D0638_RS05030	COG0612	Peptidase, M16
D0638_RS05035	COG0612	Peptidase, M16
D0638_RS05040	COG1028	Short-chain dehydrogenase reductase Sdr
D0638_RS05045	COG1426	Protein conserved in bacteria
D0638_RS05050	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
D0638_RS05065	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
D0638_RS05085	COG1739	Uncharacterized protein family UPF0029
D0638_RS05090	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
D0638_RS05115	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
D0638_RS05120	COG2884	Cell division ATP-binding protein ftsE
D0638_RS05125	COG2177	Part of the ABC transporter FtsEX involved in
D0638_RS05135	COG0745	RESPONSE REGULATOR receiver
D0638_RS05140	COG5002	protein histidine kinase activity
D0638_RS05150	COG0573	inorganic phosphate transmembrane transporter activity
D0638_RS05155	COG0581	inorganic phosphate transmembrane transporter activity
D0638_RS05160	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
D0638_RS05165	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
D0638_RS05170	COG0704	Plays a role in the regulation of phosphate uptake
D0638_RS05185	COG1950	PFAM Membrane protein of
D0638_RS05195	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
D0638_RS05205	COG0492	ferredoxin-NADP+ reductase activity
D0638_RS05215	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
D0638_RS05220	COG0745	RESPONSE REGULATOR receiver
D0638_RS05225	COG2205	protein histidine kinase activity
D0638_RS05230	COG1136	(ABC) transporter
D0638_RS05260	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
D0638_RS05280	COG0391	Required for morphogenesis under gluconeogenic growth conditions
D0638_RS05290	COG1846	Transcriptional regulator
D0638_RS05315	COG2176	DNA-directed DNA polymerase activity
D0638_RS05320	COG2390	Transcriptional regulator
D0638_RS05360	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
D0638_RS05370	COG0557	exoribonuclease II activity
D0638_RS05380	COG1609	Transcriptional regulator
D0638_RS05385	COG0366	Alpha amylase catalytic
D0638_RS05400	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
D0638_RS05405	COG3842	ATPase activity
D0638_RS05410	COG0366	Alpha amylase catalytic
D0638_RS05420	COG1175	transmembrane transport
D0638_RS05425	COG3833	ABC-type maltose transport systems, permease component
D0638_RS05475	COG0395	ABC-type sugar transport system, permease component
D0638_RS05480	COG1175	transmembrane transport
D0638_RS05505	COG0561	phosphatase activity
D0638_RS05515	COG0280	phosphate acetyltransferase
D0638_RS05520	COG0802	atpase or kinase
D0638_RS05530	COG4152	abc transporter atp-binding protein
D0638_RS05535	COG1668	transmembrane transport
D0638_RS05545	COG0708	Exodeoxyribonuclease III
D0638_RS05560	COG1396	sequence-specific DNA binding
D0638_RS05560	COG3800	Transcriptional regulator
D0638_RS05570	COG1176	ABC-type spermidine putrescine transport system, permease component I
D0638_RS05575	COG1177	transmembrane transport
D0638_RS05580	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
D0638_RS05595	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
D0638_RS05600	COG1309	transcriptional regulator
D0638_RS05630	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
D0638_RS05655	COG1459	type II secretion system
D0638_RS05685	COG0827	DNA restriction-modification system
D0638_RS05695	COG1113	amino acid transport
D0638_RS05745	COG0745	RESPONSE REGULATOR receiver
D0638_RS05750	COG3850	Histidine kinase
D0638_RS05750	COG5002	protein histidine kinase activity
D0638_RS05785	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
D0638_RS05845	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
D0638_RS05850	COG2814	Major facilitator Superfamily
D0638_RS05855	COG0561	phosphatase activity
D0638_RS05860	COG2326	polyphosphate kinase activity
D0638_RS05865	COG3590	peptidase
D0638_RS05870	COG2814	Major facilitator Superfamily
D0638_RS05910	COG0673	inositol 2-dehydrogenase activity
D0638_RS05920	COG1447	Phosphotransferase system cellobiose-specific component IIA
D0638_RS05940	COG0514	ATP-dependent DNA helicase (RecQ)
D0638_RS05945	COG2309	aminopeptidase activity
D0638_RS05970	COG1295	ribonuclease BN
D0638_RS05975	COG0716	FMN binding
D0638_RS05980	COG0024	Methionine aminopeptidase
D0638_RS05990	COG0463	Glycosyl transferase, family 2
D0638_RS06010	COG1210	Utp--glucose-1-phosphate uridylyltransferase
D0638_RS06065	COG2190	(PTS) system
D0638_RS06065	COG1263	PTS System
D0638_RS06065	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
D0638_RS06070	COG3711	transcriptional antiterminator
D0638_RS06085	COG4485	Bacterial membrane protein, YfhO
D0638_RS06100	COG0463	Glycosyl transferase, family 2
D0638_RS06110	COG4129	membrane
D0638_RS06130	COG1278	Cold shock
D0638_RS06140	COG1705	Flagellar rod assembly protein muramidase FlgJ
D0638_RS06155	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
D0638_RS06160	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
D0638_RS06175	COG1368	sulfuric ester hydrolase activity
D0638_RS06185	COG4975	Glucose uptake
D0638_RS06195	COG0582	viral genome integration into host DNA
D0638_RS06270	COG3561	AntA/AntB antirepressor
D0638_RS06540	COG0590	tRNA wobble adenosine to inosine editing
D0638_RS06560	COG2814	Major facilitator Superfamily
D0638_RS06565	COG3548	integral membrane protein
D0638_RS06615	COG2514	catechol 2,3-dioxygenase activity
D0638_RS06630	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
D0638_RS06635	COG1435	thymidine kinase activity
D0638_RS06645	COG2890	protein-(glutamine-N5) methyltransferase activity
D0638_RS06650	COG0009	L-threonylcarbamoyladenylate synthase
D0638_RS06665	COG0356	it plays a direct role in the translocation of protons across the membrane
D0638_RS06710	COG1077	Cell shape determining protein MreB Mrl
D0638_RS06735	COG0772	Belongs to the SEDS family
D0638_RS06740	COG0509	glycine decarboxylation via glycine cleavage system
D0638_RS06745	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
D0638_RS06750	COG1464	Belongs to the NlpA lipoprotein family
D0638_RS06755	COG1464	Belongs to the NlpA lipoprotein family
D0638_RS06765	COG2011	ABC-type metal ion transport system permease component
D0638_RS06775	COG0719	Fe-S assembly protein
D0638_RS06780	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
D0638_RS06785	COG0822	iron-sulfur transferase activity
D0638_RS06790	COG0719	Fe-S assembly protein
D0638_RS06820	COG0589	response to stress
D0638_RS06840	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
D0638_RS06845	COG2918	glutathione biosynthetic process
D0638_RS06845	COG0189	ligase activity
D0638_RS06850	COG5506	Protein of unknown function (DUF1694)
D0638_RS06860	COG1760	l-serine dehydratase
D0638_RS06865	COG1760	l-serine dehydratase
D0638_RS06880	COG1028	Short-chain dehydrogenase reductase Sdr
D0638_RS06890	COG1428	Deoxynucleoside kinase
D0638_RS06905	COG4166	transmembrane transport
D0638_RS06910	COG2205	protein histidine kinase activity
D0638_RS06915	COG0745	RESPONSE REGULATOR receiver
D0638_RS06935	COG0583	DNA-binding transcription factor activity
D0638_RS06970	COG0454	-acetyltransferase
D0638_RS06985	COG1307	EDD domain protein, DegV family
D0638_RS06990	COG2197	response regulator
D0638_RS06995	COG4585	Histidine kinase
D0638_RS07005	COG1131	(ABC) transporter
D0638_RS07015	COG0789	Transcriptional regulator
D0638_RS07050	COG2183	response to ionizing radiation
D0638_RS07055	COG3620	sequence-specific DNA binding
D0638_RS07115	COG1956	GAF domain-containing protein
D0638_RS07120	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
D0638_RS07125	COG1104	cysteine desulfurase activity
D0638_RS07140	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
D0638_RS07145	COG0525	valine-tRNA ligase activity
D0638_RS07160	COG2003	Belongs to the UPF0758 family
D0638_RS07165	COG1077	Cell shape determining protein MreB Mrl
D0638_RS07170	COG1792	Involved in formation and maintenance of cell shape
D0638_RS07180	COG0850	regulation of cytokinetic process
D0638_RS07185	COG2894	cell division
D0638_RS07190	COG0765	amino acid transport
D0638_RS07200	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
D0638_RS07205	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
D0638_RS07225	COG2001	Belongs to the MraZ family
D0638_RS07240	COG0768	penicillin binding
D0638_RS07270	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
D0638_RS07290	COG3599	regulation of cell shape
D0638_RS07300	COG1278	Cold shock
D0638_RS07310	COG2814	Major facilitator Superfamily
D0638_RS07315	COG3853	Toxic anion resistance protein (TelA)
D0638_RS07325	COG0494	nUDIX hydrolase
D0638_RS07340	COG1104	cysteine desulfurase activity
D0638_RS07385	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
D0638_RS07395	COG1597	lipid kinase activity
D0638_RS07465	COG0483	inositol monophosphate 1-phosphatase activity
D0638_RS07470	COG1217	gtp-binding protein TYPA
D0638_RS07475	COG0772	Belongs to the SEDS family
D0638_RS07485	COG4471	UPF0298 protein
D0638_RS07490	COG0742	ribosomal rna small subunit methyltransferase
D0638_RS07500	COG3480	Lon protease (S16) C-terminal proteolytic domain
D0638_RS07510	COG2333	competence protein COMEC
D0638_RS07510	COG0658	competence protein
D0638_RS07515	COG1466	dna polymerase III delta subunit
D0638_RS07560	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
D0638_RS07575	COG1132	(ABC) transporter
D0638_RS07585	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
D0638_RS07610	COG0765	amino acid transport
D0638_RS07615	COG1126	abc transporter atp-binding protein
D0638_RS07625	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
D0638_RS07625	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
D0638_RS07625	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
D0638_RS07630	COG1105	Belongs to the carbohydrate kinase PfkB family
D0638_RS07635	COG1349	DNA-binding transcription factor activity
D0638_RS07645	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
D0638_RS07645	COG2755	lipolytic protein G-D-S-L family
D0638_RS07655	COG0300	oxidoreductase activity
D0638_RS07670	COG0542	response to heat
D0638_RS07685	COG0737	Belongs to the 5'-nucleotidase family
D0638_RS07700	COG0587	DNA-directed DNA polymerase activity
D0638_RS07720	COG2996	Protein conserved in bacteria
D0638_RS07730	COG0456	acetyltransferase
D0638_RS07735	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
D0638_RS07740	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
D0638_RS07745	COG1187	pseudouridine synthase activity
D0638_RS07750	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
D0638_RS07765	COG0514	ATP-dependent DNA helicase (RecQ)
D0638_RS07780	COG0539	negative regulation of cytoplasmic translation
D0638_RS07795	COG0457	Tetratricopeptide repeat
D0638_RS07800	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
D0638_RS07815	COG0488	(ABC) transporter
D0638_RS07830	COG1272	protein, Hemolysin III
D0638_RS07835	COG1307	EDD domain protein, DegV family
D0638_RS07840	COG2755	lipolytic protein G-D-S-L family
D0638_RS07850	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
D0638_RS07860	COG0793	Belongs to the peptidase S41A family
D0638_RS07860	COG3409	Peptidoglycan-binding domain 1 protein
D0638_RS07910	COG1196	nuclear chromosome segregation
D0638_RS07915	COG1396	sequence-specific DNA binding
D0638_RS07920	COG2946	Replication initiation factor
D0638_RS07945	COG0758	DNA mediated transformation
D0638_RS07955	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
D0638_RS07980	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
D0638_RS08000	COG0187	DNA topoisomerase II activity
D0638_RS08005	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
D0638_RS08010	COG1882	Formate acetyltransferase
D0638_RS08015	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
D0638_RS08020	COG0583	DNA-binding transcription factor activity
D0638_RS08025	COG1227	inorganic diphosphatase activity
D0638_RS08030	COG4974	Belongs to the 'phage' integrase family
D0638_RS08040	COG0577	efflux transmembrane transporter activity
D0638_RS08045	COG1136	(ABC) transporter
D0638_RS08050	COG5002	protein histidine kinase activity
D0638_RS08055	COG0745	RESPONSE REGULATOR receiver
D0638_RS08075	COG0778	Nitroreductase
D0638_RS08080	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
D0638_RS08115	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
D0638_RS08130	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
D0638_RS08135	COG0494	nUDIX hydrolase
D0638_RS08140	COG1307	EDD domain protein, DegV family
D0638_RS08145	COG1293	RNA-binding protein homologous to eukaryotic snRNP
D0638_RS08160	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
D0638_RS08165	COG0508	dehydrogenase complex catalyzes the overall conversion of
D0638_RS08170	COG0022	dehydrogenase e1 component
D0638_RS08175	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
D0638_RS08180	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
D0638_RS08185	COG3426	butyrate kinase activity
D0638_RS08190	COG0280	phosphate acetyltransferase
D0638_RS08195	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
D0638_RS08200	COG0284	orotidine-5'-phosphate decarboxylase activity
D0638_RS08215	COG0505	Belongs to the CarA family
D0638_RS08230	COG2233	PERMEase
D0638_RS08235	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
D0638_RS08240	COG0564	pseudouridine synthase activity
D0638_RS08245	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
D0638_RS08260	COG0328	RNA-DNA hybrid ribonuclease activity
D0638_RS08280	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
D0638_RS08300	COG1393	Belongs to the ArsC family
D0638_RS08310	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
D0638_RS08320	COG0583	DNA-binding transcription factor activity
D0638_RS08325	COG3590	peptidase
D0638_RS08330	COG0095	Lipoate-protein ligase
D0638_RS08345	COG0116	Belongs to the methyltransferase superfamily
D0638_RS08375	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
D0638_RS08390	COG2131	deaminase
D0638_RS08395	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
D0638_RS08410	COG0436	Aminotransferase
D0638_RS08420	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
D0638_RS08420	COG1199	ATP-dependent helicase activity
D0638_RS08455	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
D0638_RS08455	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
D0638_RS08470	COG2151	metal-sulfur cluster biosynthetic enzyme
D0638_RS08475	COG1942	4-Oxalocrotonate Tautomerase
D0638_RS08480	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
D0638_RS08485	COG2384	SAM-dependent methyltransferase
D0638_RS08490	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
D0638_RS08495	COG0358	DNA primase activity
D0638_RS08525	COG1381	Involved in DNA repair and RecF pathway recombination
D0638_RS08535	COG0295	cytidine deaminase activity
D0638_RS08550	COG1702	phosphate starvation-inducible protein PhoH
D0638_RS08555	COG1610	YqeY-like protein
D0638_RS08570	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
D0638_RS08575	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
D0638_RS08580	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
D0638_RS08615	COG1131	(ABC) transporter
D0638_RS08625	COG0860	N-Acetylmuramoyl-L-alanine amidase
D0638_RS08625	COG3103	Sh3 type 3 domain protein
D0638_RS08625	COG4991	sh3 domain protein
D0638_RS08640	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
D0638_RS08650	COG1385	rRNA (uridine-N3-)-methyltransferase activity
D0638_RS08665	COG2094	Belongs to the DNA glycosylase MPG family
D0638_RS08705	COG0673	inositol 2-dehydrogenase activity
D0638_RS08710	COG0438	transferase activity, transferring glycosyl groups
D0638_RS08755	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
D0638_RS08770	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
D0638_RS08770	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
D0638_RS08800	COG1132	(ABC) transporter
D0638_RS08820	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
D0638_RS08830	COG0635	Involved in the biosynthesis of porphyrin-containing compound
D0638_RS08835	COG0196	riboflavin kinase activity
D0638_RS08845	COG0861	Integral membrane protein TerC family
D0638_RS08870	COG2740	Nucleic-acid-binding protein implicated in transcription termination
D0638_RS08875	COG0195	Participates in both transcription termination and antitermination
D0638_RS08895	COG0750	zinc metalloprotease
D0638_RS08900	COG4589	Belongs to the CDS family
D0638_RS08905	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
D0638_RS08935	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
D0638_RS08940	COG0204	Acyl-transferase
D0638_RS08945	COG0531	amino acid
D0638_RS08955	COG1132	(ABC) transporter
D0638_RS08960	COG1132	(ABC) transporter
D0638_RS08965	COG3763	UPF0154 protein
D0638_RS08970	COG4224	UPF0291 protein
D0638_RS08995	COG1837	Belongs to the UPF0109 family
D0638_RS09005	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
D0638_RS09020	COG0552	protein localization to endoplasmic reticulum
D0638_RS09025	COG1196	nuclear chromosome segregation
D0638_RS09030	COG0571	ribonuclease III activity
D0638_RS09040	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
D0638_RS09045	COG0601	transmembrane transport
D0638_RS09050	COG4608	Belongs to the ABC transporter superfamily
D0638_RS09060	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
D0638_RS09070	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
D0638_RS09075	COG1461	Dihydroxyacetone kinase
D0638_RS09095	COG1564	THIamine pyrophosphokinase
D0638_RS09100	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
D0638_RS09105	COG1162	GTPase activity
D0638_RS09120	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
D0638_RS09120	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
D0638_RS09130	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
D0638_RS09135	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
D0638_RS09145	COG0194	GDP metabolic process
D0638_RS09165	COG0497	DNA recombination
D0638_RS09170	COG1438	arginine binding
D0638_RS09175	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
D0638_RS09180	COG0142	geranyltranstransferase activity
D0638_RS09185	COG1722	exodeoxyribonuclease VII activity
D0638_RS09205	COG1302	Protein conserved in bacteria
D0638_RS09210	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
D0638_RS09220	COG0211	Belongs to the bacterial ribosomal protein bL27 family
D0638_RS09225	COG2868	ribosomal protein
D0638_RS09230	COG0261	This protein binds to 23S rRNA in the presence of protein L20
D0638_RS09265	COG0789	Transcriptional regulator
D0638_RS09270	COG1982	Orn Lys Arg decarboxylase major
D0638_RS09275	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
D0638_RS09290	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
D0638_RS09295	COG1940	carbohydrate kinase activity
D0638_RS09310	COG0768	penicillin binding
D0638_RS09320	COG4841	protein insertion into membrane
D0638_RS09325	COG2197	response regulator
D0638_RS09340	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
D0638_RS09345	COG0572	uridine kinase
D0638_RS09350	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
D0638_RS09360	COG0072	phenylalanine-tRNA ligase activity
D0638_RS09375	COG1733	regulation of RNA biosynthetic process
D0638_RS09385	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
D0638_RS09395	COG0706	membrane insertase activity
D0638_RS09400	COG5002	protein histidine kinase activity
D0638_RS09405	COG0745	RESPONSE REGULATOR receiver
D0638_RS09410	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
D0638_RS09435	COG2226	methyltransferase
D0638_RS09440	COG0799	negative regulation of ribosome biogenesis
D0638_RS09450	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
D0638_RS09455	COG1534	Rna-binding protein
D0638_RS09460	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
D0638_RS09465	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
D0638_RS09470	COG0346	lactoylglutathione lyase activity
D0638_RS09480	COG0400	carboxylic ester hydrolase activity
D0638_RS09505	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
D0638_RS09535	COG1484	DNA-dependent DNA replication
D0638_RS09540	COG3611	Membrane attachment protein
D0638_RS09550	COG0237	dephospho-CoA kinase activity
D0638_RS09555	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
D0638_RS09560	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
D0638_RS09560	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
D0638_RS09565	COG0670	Belongs to the BI1 family
D0638_RS09575	COG1674	ftsk spoiiie
D0638_RS09580	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
D0638_RS09585	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
D0638_RS09610	COG1131	(ABC) transporter
D0638_RS09615	COG0537	adenosine 5'-monophosphoramidase activity
D0638_RS09625	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
D0638_RS09640	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
D0638_RS09645	COG0564	pseudouridine synthase activity
D0638_RS09650	COG1438	arginine binding
D0638_RS09660	COG0018	arginyl-trna synthetase
D0638_RS09685	COG0167	dihydroorotate dehydrogenase activity
D0638_RS09705	COG1393	Belongs to the ArsC family
D0638_RS09710	COG1234	tRNA 3'-trailer cleavage
D0638_RS09725	COG1136	(ABC) transporter
D0638_RS09730	COG0745	RESPONSE REGULATOR receiver
D0638_RS09735	COG0642	Histidine kinase
D0638_RS09745	COG2217	Heavy metal translocating P-type atpase
D0638_RS09750	COG3682	Transcriptional regulator
D0638_RS09765	COG0151	Belongs to the GarS family
D0638_RS09780	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
D0638_RS09785	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
D0638_RS09805	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
D0638_RS09815	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
D0638_RS09820	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
D0638_RS09840	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
D0638_RS09850	COG0542	response to heat
D0638_RS09865	COG1253	flavin adenine dinucleotide binding
D0638_RS09870	COG0628	permease
D0638_RS09885	COG3557	Belongs to the UPF0374 family
D0638_RS09910	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
D0638_RS09925	COG2188	Transcriptional regulator
D0638_RS09930	COG2723	6-phospho-beta-galactosidase activity
D0638_RS09935	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
D0638_RS09945	COG1447	Phosphotransferase system cellobiose-specific component IIA
D0638_RS09950	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
D0638_RS09960	COG0028	Belongs to the TPP enzyme family
D0638_RS09965	COG3425	synthase
D0638_RS09975	COG0183	Belongs to the thiolase family
D0638_RS10000	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
D0638_RS10020	COG3091	SprT-like family
D0638_RS10025	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
D0638_RS10030	COG4120	Belongs to the binding-protein-dependent transport system permease family
D0638_RS10065	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
D0638_RS10075	COG2188	Transcriptional regulator
D0638_RS10085	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
D0638_RS10090	COG4946	Tricorn protease homolog
D0638_RS10090	COG0823	Involved in the tonB-independent uptake of proteins
D0638_RS10090	COG1506	peptidase
D0638_RS10105	COG3104	oligopeptide transport
D0638_RS10115	COG0577	efflux transmembrane transporter activity
D0638_RS10115	COG1136	(ABC) transporter
D0638_RS10240	COG0833	amino acid
D0638_RS10255	COG0028	Belongs to the TPP enzyme family
D0638_RS10265	COG0519	Catalyzes the synthesis of GMP from XMP
D0638_RS10290	COG0564	pseudouridine synthase activity
D0638_RS10310	COG3697	Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase
D0638_RS10310	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
D0638_RS10330	COG3697	Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase
D0638_RS10330	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
D0638_RS10365	COG0511	ligase activity, forming carbon-carbon bonds
D0638_RS10375	COG2851	Citrate transporter
D0638_RS10415	COG1131	(ABC) transporter
D0638_RS10430	COG2814	Major facilitator Superfamily
D0638_RS10450	COG1725	Transcriptional regulator
D0638_RS10455	COG1131	(ABC) transporter
D0638_RS10470	COG4608	Belongs to the ABC transporter superfamily
D0638_RS10475	COG0444	Belongs to the ABC transporter superfamily
D0638_RS10485	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
D0638_RS10490	COG0601	transmembrane transport
D0638_RS10495	COG4166	transmembrane transport
D0638_RS10505	COG0640	Transcriptional regulator
D0638_RS10520	COG1132	(ABC) transporter
D0638_RS10545	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
D0638_RS10545	COG5549	protein import
D0638_RS10555	COG1349	DNA-binding transcription factor activity
D0638_RS10615	COG4690	dipeptidase activity
D0638_RS10620	COG1607	acyl-coa hydrolase
D0638_RS10625	COG3973	AAA domain
D0638_RS10640	COG0569	domain protein
D0638_RS10640	COG0475	glutathione-regulated potassium exporter activity
D0638_RS10645	COG2267	carboxylic ester hydrolase activity
D0638_RS10680	COG1136	(ABC) transporter
D0638_RS10685	COG0531	amino acid
D0638_RS10695	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
D0638_RS10700	COG0726	polysaccharide deacetylase
D0638_RS10715	COG0489	protein tyrosine kinase activity
D0638_RS10735	COG0463	Glycosyl transferase, family 2
D0638_RS10765	COG0463	Glycosyl transferase, family 2
D0638_RS10770	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
D0638_RS10780	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
D0638_RS10800	COG0765	amino acid transport
D0638_RS10805	COG0765	amino acid transport
D0638_RS10810	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
D0638_RS10840	COG0735	belongs to the Fur family
D0638_RS10850	COG0194	GDP metabolic process
D0638_RS10855	COG0454	-acetyltransferase
D0638_RS10855	COG0456	acetyltransferase
D0638_RS10865	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
D0638_RS10890	COG0058	SHG alpha-glucan phosphorylase activity
D0638_RS10900	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
D0638_RS10915	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
D0638_RS10925	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
D0638_RS10935	COG1393	Belongs to the ArsC family
D0638_RS10945	COG4464	protein tyrosine phosphatase activity
D0638_RS10950	COG1316	TRANSCRIPTIONal
D0638_RS10965	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
D0638_RS10985	COG0562	UDP-galactopyranose mutase
D0638_RS10990	COG0489	protein tyrosine kinase activity
D0638_RS11025	COG4708	membrane
D0638_RS11030	COG1028	Short-chain dehydrogenase reductase Sdr
D0638_RS11055	COG4608	Belongs to the ABC transporter superfamily
D0638_RS11060	COG0444	Belongs to the ABC transporter superfamily
D0638_RS11065	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
D0638_RS11070	COG0601	transmembrane transport
D0638_RS11075	COG4166	transmembrane transport
D0638_RS11080	COG2814	Major facilitator Superfamily
D0638_RS11085	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
D0638_RS11095	COG1556	Lactate utilization protein
D0638_RS11100	COG1139	Iron-sulfur cluster binding protein
D0638_RS11120	COG1447	Phosphotransferase system cellobiose-specific component IIA
D0638_RS11140	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
D0638_RS11190	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
D0638_RS11270	COG0366	Alpha amylase catalytic
D0638_RS11275	COG1609	Transcriptional regulator
D0638_RS11295	COG0702	epimerase
D0638_RS11300	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
D0638_RS11315	COG0439	Biotin carboxylase
D0638_RS11330	COG0511	ligase activity, forming carbon-carbon bonds
D0638_RS11340	COG1028	Short-chain dehydrogenase reductase Sdr
D0638_RS11355	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
D0638_RS11360	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
D0638_RS11370	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
D0638_RS11385	COG2267	carboxylic ester hydrolase activity
D0638_RS11390	COG1979	alcohol dehydrogenase
D0638_RS11435	COG1846	Transcriptional regulator
D0638_RS11440	COG1132	(ABC) transporter
D0638_RS11445	COG0494	nUDIX hydrolase
D0638_RS11455	COG0588	phosphoglycerate mutase activity
D0638_RS11475	COG0628	permease
D0638_RS11495	COG1597	lipid kinase activity
D0638_RS11500	COG0028	Belongs to the TPP enzyme family
D0638_RS11545	COG0460	homoserine dehydrogenase
D0638_RS11550	COG0527	aspartate kinase activity
D0638_RS11555	COG2268	Band 7 protein
D0638_RS11570	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
D0638_RS11575	COG0436	Aminotransferase
D0638_RS11600	COG0367	asparagine synthase
D0638_RS11615	COG0142	geranyltranstransferase activity
D0638_RS11625	COG4152	abc transporter atp-binding protein
D0638_RS11665	COG1297	OPT oligopeptide transporter protein
D0638_RS11685	COG0477	Major facilitator Superfamily
D0638_RS11700	COG2723	6-phospho-beta-galactosidase activity
D0638_RS11705	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
D0638_RS11705	COG1263	PTS System
D0638_RS11705	COG2190	(PTS) system
D0638_RS11715	COG1132	(ABC) transporter
D0638_RS11720	COG1132	(ABC) transporter
D0638_RS11745	COG1518	maintenance of DNA repeat elements
D0638_RS11750	COG3513	CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
D0638_RS11775	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
D0638_RS11780	COG4988	ABC transporter
D0638_RS11785	COG1294	oxidase, subunit
D0638_RS11790	COG1271	oxidase subunit
D0638_RS11820	COG0697	spore germination
D0638_RS11825	COG2818	Glycosylase
D0638_RS11840	COG2365	Tyrosine phosphatase family
D0638_RS11845	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
D0638_RS11855	COG1268	BioY protein
D0638_RS11860	COG0789	Transcriptional regulator
D0638_RS11895	COG2264	protein methyltransferase activity
D0638_RS11905	COG0505	Belongs to the CarA family
D0638_RS11915	COG1253	flavin adenine dinucleotide binding
D0638_RS11920	COG2814	Major facilitator Superfamily
D0638_RS11955	COG0531	amino acid
D0638_RS11980	COG1266	CAAX protease self-immunity
D0638_RS11985	COG1316	TRANSCRIPTIONal
D0638_RS11995	COG1131	(ABC) transporter
D0638_RS12000	COG1725	Transcriptional regulator
D0638_RS12005	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
D0638_RS12010	COG0488	(ABC) transporter
D0638_RS12025	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
D0638_RS12035	COG1214	PFAM Peptidase M22, glycoprotease
D0638_RS12035	COG0456	acetyltransferase
D0638_RS12040	COG1214	PFAM Peptidase M22, glycoprotease
D0638_RS12090	COG0470	DNA polymerase III
D0638_RS12095	COG3870	Protein conserved in bacteria
D0638_RS12130	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
D0638_RS12145	COG0590	tRNA wobble adenosine to inosine editing
D0638_RS12155	COG2813	Specifically methylates the guanine in position
D0638_RS12170	COG1609	Transcriptional regulator
D0638_RS12220	COG0477	Major facilitator Superfamily
D0638_RS12240	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
D0638_RS12250	COG5646	InterPro IPR014922
D0638_RS12255	COG2096	Adenosyltransferase
D0638_RS12285	COG0250	Participates in transcription elongation, termination and antitermination
D0638_RS12315	COG4939	FMN-binding domain protein
D0638_RS12355	COG1131	(ABC) transporter
D0638_RS12385	COG3688	RNA-binding protein containing a PIN domain
D0638_RS12390	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
D0638_RS12395	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
D0638_RS12410	COG0277	FAD linked oxidase domain protein
D0638_RS12440	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
D0638_RS12445	COG1737	Transcriptional regulator
D0638_RS12450	COG4377	Putative membrane peptidase family (DUF2324)
D0638_RS12465	COG4886	Leucine-rich repeat (LRR) protein
D0638_RS12465	COG4932	domain protein
D0638_RS12510	COG4956	integral membrane protein (PIN domain superfamily)
D0638_RS12515	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
D0638_RS12520	COG0756	dUTP diphosphatase activity
D0638_RS12525	COG2388	GCN5-related N-acetyl-transferase
D0638_RS12530	COG3152	Membrane
D0638_RS12560	COG1131	(ABC) transporter
D0638_RS12570	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
D0638_RS12570	COG0574	Belongs to the PEP-utilizing enzyme family
D0638_RS12575	COG0517	IMP dehydrogenase activity
D0638_RS12580	COG0588	phosphoglycerate mutase activity
D0638_RS12595	COG1304	FMN binding
D0638_RS12635	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
D0638_RS12660	COG3764	Sortase (surface protein transpeptidase)
D0638_RS12710	COG1695	Transcriptional regulator
D0638_RS12755	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
D0638_RS12760	COG2274	protein secretion by the type I secretion system
D0638_RS12835	COG0110	maltose O-acetyltransferase activity
D0638_RS12860	COG4989	oxidoreductase activity
D0638_RS12865	COG4221	oxidoreductase activity
D0638_RS12870	COG1902	pentaerythritol trinitrate reductase activity
D0638_RS12890	COG1914	H( )-stimulated, divalent metal cation uptake system
D0638_RS12895	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
D0638_RS12905	COG2814	Major facilitator Superfamily
D0638_RS12935	COG1108	ABC-type Mn2 Zn2 transport systems permease components
D0638_RS12940	COG1121	(ABC) transporter
D0638_RS12945	COG1012	belongs to the aldehyde dehydrogenase family
D0638_RS13040	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
D0638_RS13055	COG0148	phosphopyruvate hydratase activity
D0638_RS13060	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
D0638_RS13080	COG3639	organic phosphonate transmembrane transporter activity
D0638_RS13100	COG1116	anion transmembrane transporter activity
D0638_RS13105	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
D0638_RS13120	COG4555	ABC transporter
D0638_RS13160	COG0577	efflux transmembrane transporter activity
D0638_RS13165	COG1136	(ABC) transporter
D0638_RS13180	COG0789	Transcriptional regulator
D0638_RS13260	COG0200	Binds to the 23S rRNA
D0638_RS13370	COG0450	alkyl hydroperoxide reductase
D0638_RS13425	COG0542	response to heat
D0638_RS13430	COG4463	regulation of RNA biosynthetic process
D0638_RS13500	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
D0638_RS13505	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
D0638_RS13545	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
D0638_RS13550	COG0037	tRNA processing
D0638_RS13555	COG1098	S1 RNA binding domain
D0638_RS13565	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
D0638_RS13570	COG2244	polysaccharide biosynthetic process
D0638_RS13575	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
D0638_RS13585	COG0039	L-malate dehydrogenase activity
D0638_RS13615	COG1376	ErfK ybiS ycfS ynhG family protein
D0638_RS13620	COG0493	'glutamate synthase
D0638_RS13630	COG0070	glutamate synthase
D0638_RS13630	COG0069	glutamate synthase activity
D0638_RS13630	COG0067	glutamate synthase
D0638_RS13640	COG4708	membrane
D0638_RS13645	COG2337	Toxic component of a toxin-antitoxin (TA) module
D0638_RS13670	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
D0638_RS13715	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
D0638_RS13725	COG0504	CTP synthase activity
D0638_RS13745	COG0095	Lipoate-protein ligase
D0638_RS13750	COG1078	dGTPase activity
D0638_RS13780	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
D0638_RS13785	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
D0638_RS13795	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
D0638_RS13815	COG0390	transport system, permease component
D0638_RS13825	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
D0638_RS13830	COG4466	Protein conserved in bacteria
D0638_RS13835	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
D0638_RS13840	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
D0638_RS13845	COG0084	hydrolase, TatD family'
D0638_RS13855	COG3684	Belongs to the aldolase LacD family
D0638_RS13870	COG3290	protein histidine kinase activity
D0638_RS13885	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
D0638_RS13885	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
D0638_RS13895	COG1801	Protein of unknown function DUF72
D0638_RS13915	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
D0638_RS13930	COG1881	PFAM PEBP family protein
D0638_RS13940	COG4086	secreted protein
D0638_RS13950	COG0248	Ppx GppA phosphatase
D0638_RS13955	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
D0638_RS13970	COG4989	oxidoreductase activity
D0638_RS13975	COG2226	methyltransferase
D0638_RS13985	COG0534	Mate efflux family protein
D0638_RS13990	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
D0638_RS13995	COG1704	LemA family
D0638_RS14010	COG1136	(ABC) transporter
D0638_RS14010	COG0577	efflux transmembrane transporter activity
D0638_RS14015	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
D0638_RS14025	COG1174	glycine betaine transport
D0638_RS14035	COG3973	AAA domain
D0638_RS14065	COG1418	mRNA catabolic process
D0638_RS14075	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
D0638_RS14080	COG0667	Aldo Keto reductase
D0638_RS14085	COG0561	phosphatase activity
D0638_RS14110	COG0588	phosphoglycerate mutase activity
D0638_RS14115	COG0561	phosphatase activity
D0638_RS14130	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
D0638_RS14135	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
D0638_RS14140	COG1811	Na channel or pump
D0638_RS14165	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
D0638_RS14165	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
D0638_RS14165	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
D0638_RS14170	COG1105	Belongs to the carbohydrate kinase PfkB family
D0638_RS14180	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
D0638_RS14205	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
D0638_RS14205	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
D0638_RS14210	COG3715	PTS system
D0638_RS14215	COG3716	PTS system mannose fructose sorbose family IID component
D0638_RS14220	COG1447	Phosphotransferase system cellobiose-specific component IIA
D0638_RS14230	COG2723	6-phospho-beta-galactosidase activity
D0638_RS14235	COG1940	carbohydrate kinase activity
D0638_RS14250	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
D0638_RS14275	COG3775	system Galactitol-specific IIC component
D0638_RS14290	COG1349	DNA-binding transcription factor activity
D0638_RS14305	COG0366	Alpha amylase catalytic
D0638_RS14335	COG0463	Glycosyl transferase, family 2
D0638_RS14345	COG0586	Pfam SNARE associated Golgi protein
D0638_RS14350	COG0745	RESPONSE REGULATOR receiver
D0638_RS14360	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
D0638_RS14360	COG1263	PTS System
D0638_RS14380	COG3547	Transposase (IS116 IS110 IS902 family)
D0638_RS14405	COG3711	transcriptional antiterminator
D0638_RS14415	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
D0638_RS14415	COG1263	PTS System
D0638_RS14415	COG2190	(PTS) system
D0638_RS14460	COG3414	Phosphotransferase system galactitol-specific IIB component
D0638_RS14465	COG3775	system Galactitol-specific IIC component
D0638_RS14490	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
D0638_RS14505	COG2204	response regulator
D0638_RS14530	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
D0638_RS14535	COG0800	Aldolase
D0638_RS14565	COG3964	amidohydrolase
D0638_RS14615	COG3732	PTS system glucitol sorbitol-specific
D0638_RS14620	COG3730	PTS system glucitol sorbitol-specific
D0638_RS14630	COG3711	transcriptional antiterminator
D0638_RS14630	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
D0638_RS14645	COG0561	phosphatase activity
D0638_RS14650	COG3623	hexulose-6-phosphate isomerase
D0638_RS14655	COG1349	DNA-binding transcription factor activity
D0638_RS14660	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
D0638_RS14675	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
D0638_RS14700	COG3775	system Galactitol-specific IIC component
D0638_RS14710	COG0395	ABC-type sugar transport system, permease component
D0638_RS14720	COG3842	ATPase activity
D0638_RS14725	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
D0638_RS14730	COG1335	isochorismatase
D0638_RS14755	COG4948	Mandelate Racemase Muconate Lactonizing
D0638_RS14760	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
D0638_RS14765	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
D0638_RS14770	COG1737	Transcriptional regulator
D0638_RS14775	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
D0638_RS14780	COG3716	PTS system mannose fructose sorbose family IID component
D0638_RS14800	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
D0638_RS14805	COG1397	ADP-ribosylglycohydrolase
D0638_RS14810	COG2076	Multidrug Resistance protein
D0638_RS14850	COG0604	alcohol dehydrogenase
D0638_RS14855	COG2365	Tyrosine phosphatase family
D0638_RS14885	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
D0638_RS14900	COG4166	transmembrane transport
D0638_RS14915	COG2217	Heavy metal translocating P-type atpase
D0638_RS14930	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
D0638_RS14945	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
D0638_RS14960	COG5002	protein histidine kinase activity
D0638_RS14965	COG0745	RESPONSE REGULATOR receiver
D0638_RS14970	COG2267	carboxylic ester hydrolase activity
D0638_RS14975	COG0765	amino acid transport
D0638_RS15010	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
D0638_RS15015	COG2188	Transcriptional regulator
D0638_RS15020	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
D0638_RS15025	COG1447	Phosphotransferase system cellobiose-specific component IIA
D0638_RS15055	COG1335	isochorismatase
D0638_RS15065	COG2814	Major facilitator Superfamily
D0638_RS15070	COG2807	transmembrane transport
D0638_RS15075	COG0667	Aldo Keto reductase
D0638_RS15085	COG3716	PTS system mannose fructose sorbose family IID component
D0638_RS15090	COG3715	PTS system
D0638_RS15120	COG0765	amino acid transport
D0638_RS15125	COG1126	abc transporter atp-binding protein
D0638_RS15165	COG4133	protoheme IX ABC transporter activity
D0638_RS15170	COG3001	Fructosamine kinase
D0638_RS15175	COG1126	abc transporter atp-binding protein
D0638_RS15180	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
D0638_RS15185	COG0765	amino acid transport
D0638_RS15200	COG0714	Associated with various cellular activities
D0638_RS15210	COG1305	Transglutaminase-like
D0638_RS15215	COG0438	transferase activity, transferring glycosyl groups
D0638_RS15220	COG0110	maltose O-acetyltransferase activity
D0638_RS15225	COG0561	phosphatase activity
D0638_RS15250	COG3493	citrate carrier protein
D0638_RS15255	COG3290	protein histidine kinase activity
D0638_RS15260	COG4565	transcriptional regulatory protein
D0638_RS15290	COG1263	PTS System
D0638_RS15290	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
D0638_RS15295	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
D0638_RS15295	COG2190	(PTS) system
D0638_RS15295	COG1263	PTS System
D0638_RS15300	COG3711	transcriptional antiterminator
D0638_RS15315	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
D0638_RS15335	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
D0638_RS15345	COG2213	PTS system mannitol-specific
D0638_RS15360	COG0561	phosphatase activity
D0638_RS15380	COG1136	(ABC) transporter
D0638_RS15385	COG0577	efflux transmembrane transporter activity
D0638_RS15395	COG0371	Dehydrogenase
D0638_RS15400	COG1473	amidohydrolase
D0638_RS15440	COG0706	membrane insertase activity
D0638_RS15560	COG1192	Involved in chromosome partitioning
D0638_RS15600	COG1937	Protein conserved in bacteria
D0638_RS15605	COG3118	belongs to the thioredoxin family
D0638_RS15670	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
