locus-tag	class	description
GWC93_RS00110	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
GWC93_RS00150	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
GWC93_RS00160	COG1187	pseudouridine synthase activity
GWC93_RS00165	COG2244	polysaccharide biosynthetic process
GWC93_RS00175	COG0671	phosphoesterase, PA-phosphatase related
GWC93_RS00185	COG2814	Major facilitator Superfamily
GWC93_RS00195	COG0477	Major facilitator Superfamily
GWC93_RS00240	COG0735	belongs to the Fur family
GWC93_RS00245	COG1368	sulfuric ester hydrolase activity
GWC93_RS00255	COG0436	Aminotransferase
GWC93_RS00270	COG0438	transferase activity, transferring glycosyl groups
GWC93_RS00275	COG0438	transferase activity, transferring glycosyl groups
GWC93_RS00280	COG0531	amino acid
GWC93_RS00430	COG1098	S1 RNA binding domain
GWC93_RS00445	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
GWC93_RS00450	COG0586	Pfam SNARE associated Golgi protein
GWC93_RS00460	COG0647	UMP catabolic process
GWC93_RS00465	COG4470	Protein conserved in bacteria
GWC93_RS00470	COG0737	Belongs to the 5'-nucleotidase family
GWC93_RS00510	COG1011	Hydrolase
GWC93_RS00515	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GWC93_RS00520	COG1609	Transcriptional regulator
GWC93_RS00525	COG0006	proline dipeptidase activity
GWC93_RS00530	COG1827	regulation of RNA biosynthetic process
GWC93_RS00545	COG0668	transmembrane transport
GWC93_RS00560	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
GWC93_RS00570	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
GWC93_RS00575	COG1719	4-vinyl reductase, 4VR
GWC93_RS00580	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
GWC93_RS00590	COG1696	Membrane protein involved in D-alanine export
GWC93_RS00605	COG3118	belongs to the thioredoxin family
GWC93_RS00650	COG0513	Belongs to the DEAD box helicase family
GWC93_RS00655	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
GWC93_RS00660	COG4109	DRTGG domain
GWC93_RS00665	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
GWC93_RS00670	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
GWC93_RS00680	COG1012	belongs to the aldehyde dehydrogenase family
GWC93_RS00680	COG1454	alcohol dehydrogenase
GWC93_RS00685	COG1862	Preprotein translocase
GWC93_RS00690	COG0343	queuine tRNA-ribosyltransferase activity
GWC93_RS00695	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
GWC93_RS00720	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
GWC93_RS00755	COG2267	carboxylic ester hydrolase activity
GWC93_RS00785	COG2267	carboxylic ester hydrolase activity
GWC93_RS00790	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
GWC93_RS00795	COG0105	UTP biosynthetic process
GWC93_RS00800	COG0300	oxidoreductase activity
GWC93_RS00825	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
GWC93_RS00850	COG3189	MarR family transcriptional regulator
GWC93_RS00855	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
GWC93_RS00865	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
GWC93_RS00890	COG0628	permease
GWC93_RS00905	COG0604	alcohol dehydrogenase
GWC93_RS00955	COG4695	Portal protein
GWC93_RS01035	COG1304	FMN binding
GWC93_RS01040	COG0778	Nitroreductase
GWC93_RS01055	COG2508	Transcriptional regulator
GWC93_RS01065	COG5002	protein histidine kinase activity
GWC93_RS01070	COG0745	RESPONSE REGULATOR receiver
GWC93_RS01080	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
GWC93_RS01085	COG0463	Glycosyl transferase, family 2
GWC93_RS01095	COG0604	alcohol dehydrogenase
GWC93_RS01105	COG4120	Belongs to the binding-protein-dependent transport system permease family
GWC93_RS01120	COG1472	Belongs to the glycosyl hydrolase 3 family
GWC93_RS01125	COG2910	NAD(P)H-binding
GWC93_RS01140	COG0351	phosphomethylpyrimidine kinase
GWC93_RS01160	COG2249	NAD(P)H dehydrogenase (quinone) activity
GWC93_RS01170	COG1194	a g-specific adenine glycosylase
GWC93_RS01185	COG0419	ATPase involved in DNA repair
GWC93_RS01200	COG1349	DNA-binding transcription factor activity
GWC93_RS01215	COG3684	Belongs to the aldolase LacD family
GWC93_RS01235	COG3775	system Galactitol-specific IIC component
GWC93_RS01260	COG2017	converts alpha-aldose to the beta-anomer
GWC93_RS01265	COG1609	Transcriptional regulator
GWC93_RS01270	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
GWC93_RS01275	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
GWC93_RS01285	COG1215	transferase activity, transferring glycosyl groups
GWC93_RS01290	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
GWC93_RS01300	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
GWC93_RS01305	COG1573	uracil-dna glycosylase
GWC93_RS01310	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
GWC93_RS01315	COG0488	(ABC) transporter
GWC93_RS01325	COG1131	(ABC) transporter
GWC93_RS01345	COG1285	pathogenesis
GWC93_RS01355	COG0004	ammonium transporteR
GWC93_RS01400	COG0025	NhaP-type Na H and K H
GWC93_RS01410	COG1113	amino acid transport
GWC93_RS01415	COG0656	L-ascorbic acid biosynthetic process
GWC93_RS01420	COG0702	epimerase
GWC93_RS01425	COG0488	(ABC) transporter
GWC93_RS01440	COG1278	Cold shock
GWC93_RS01445	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
GWC93_RS01450	COG0039	L-malate dehydrogenase activity
GWC93_RS01455	COG0531	amino acid
GWC93_RS01465	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GWC93_RS01465	COG2190	(PTS) system
GWC93_RS01465	COG1263	PTS System
GWC93_RS01470	COG0366	Alpha amylase catalytic
GWC93_RS01475	COG2188	Transcriptional regulator
GWC93_RS01480	COG2223	nitrite transmembrane transporter activity
GWC93_RS01485	COG1132	(ABC) transporter
GWC93_RS01490	COG1132	(ABC) transporter
GWC93_RS01495	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
GWC93_RS01500	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
GWC93_RS01515	COG1131	(ABC) transporter
GWC93_RS01525	COG0697	spore germination
GWC93_RS01575	COG1114	Component of the transport system for branched-chain amino acids
GWC93_RS01585	COG0765	amino acid transport
GWC93_RS01590	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GWC93_RS01595	COG0626	cystathionine gamma-synthase activity
GWC93_RS01610	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GWC93_RS01620	COG1174	glycine betaine transport
GWC93_RS01650	COG0390	transport system, permease component
GWC93_RS01655	COG4619	ABC transporter
GWC93_RS01680	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
GWC93_RS01690	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
GWC93_RS01725	COG3976	FMN-binding domain protein
GWC93_RS01725	COG0431	NADPH-dependent FMN reductase
GWC93_RS01725	COG1053	succinate dehydrogenase
GWC93_RS01740	COG2801	Transposase and inactivated derivatives
GWC93_RS01755	COG2801	Transposase and inactivated derivatives
GWC93_RS01765	COG0783	Belongs to the Dps family
GWC93_RS01785	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
GWC93_RS01870	COG2801	Transposase and inactivated derivatives
GWC93_RS01885	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
GWC93_RS02050	COG2801	Transposase and inactivated derivatives
GWC93_RS02080	COG2826	transposase and inactivated derivatives, IS30 family
GWC93_RS02205	COG1396	sequence-specific DNA binding
GWC93_RS02255	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
GWC93_RS02260	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
GWC93_RS02265	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
GWC93_RS02270	COG2271	Major facilitator Superfamily
GWC93_RS02280	COG1028	Short-chain dehydrogenase reductase Sdr
GWC93_RS02300	COG0531	amino acid
GWC93_RS02305	COG0308	aminopeptidase N
GWC93_RS02330	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
GWC93_RS02350	COG1131	(ABC) transporter
GWC93_RS02375	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
GWC93_RS02390	COG0656	L-ascorbic acid biosynthetic process
GWC93_RS02395	COG0789	Transcriptional regulator
GWC93_RS02410	COG0174	glutamine synthetase
GWC93_RS02415	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
GWC93_RS02420	COG2226	methyltransferase
GWC93_RS02435	COG0028	Belongs to the TPP enzyme family
GWC93_RS02455	COG2814	Major facilitator Superfamily
GWC93_RS02475	COG2376	Dihydroxyacetone kinase
GWC93_RS02480	COG1461	Dihydroxyacetone kinase
GWC93_RS02485	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
GWC93_RS02510	COG1464	Belongs to the NlpA lipoprotein family
GWC93_RS02535	COG1132	(ABC) transporter
GWC93_RS02540	COG0366	Alpha amylase catalytic
GWC93_RS02555	COG3716	PTS system mannose fructose sorbose family IID component
GWC93_RS02565	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GWC93_RS02570	COG1609	Transcriptional regulator
GWC93_RS02580	COG0561	phosphatase activity
GWC93_RS02585	COG0446	pyridine nucleotide-disulphide oxidoreductase
GWC93_RS02610	COG4221	oxidoreductase activity
GWC93_RS02630	COG0477	Major facilitator Superfamily
GWC93_RS02660	COG1349	DNA-binding transcription factor activity
GWC93_RS02665	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
GWC93_RS02670	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
GWC93_RS02675	COG1349	DNA-binding transcription factor activity
GWC93_RS02680	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GWC93_RS02730	COG1122	ATPase activity
GWC93_RS02745	COG0583	DNA-binding transcription factor activity
GWC93_RS02755	COG0471	metal ion transport
GWC93_RS02760	COG0191	fructose-bisphosphate aldolase activity
GWC93_RS02765	COG3716	PTS system mannose fructose sorbose family IID component
GWC93_RS02770	COG3715	PTS system
GWC93_RS02775	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GWC93_RS02780	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
GWC93_RS02790	COG2390	Transcriptional regulator
GWC93_RS02800	COG1609	Transcriptional regulator
GWC93_RS02805	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
GWC93_RS02810	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
GWC93_RS02815	COG2376	Dihydroxyacetone kinase
GWC93_RS02820	COG1461	Dihydroxyacetone kinase
GWC93_RS02825	COG0246	Mannitol dehydrogenase
GWC93_RS02830	COG3716	PTS system mannose fructose sorbose family IID component
GWC93_RS02835	COG3715	PTS system
GWC93_RS02840	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
GWC93_RS02840	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GWC93_RS02850	COG1028	Short-chain dehydrogenase reductase Sdr
GWC93_RS02855	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GWC93_RS02855	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GWC93_RS02855	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GWC93_RS02860	COG0191	fructose-bisphosphate aldolase activity
GWC93_RS02875	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
GWC93_RS02880	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GWC93_RS02880	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GWC93_RS02885	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GWC93_RS02885	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GWC93_RS02885	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GWC93_RS02905	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GWC93_RS02905	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GWC93_RS02905	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GWC93_RS02910	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GWC93_RS02915	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GWC93_RS02915	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GWC93_RS02915	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GWC93_RS02925	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
GWC93_RS02925	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
GWC93_RS02930	COG3711	transcriptional antiterminator
GWC93_RS02935	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
GWC93_RS02950	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GWC93_RS02955	COG3715	PTS system
GWC93_RS02960	COG3716	PTS system mannose fructose sorbose family IID component
GWC93_RS02970	COG0641	radical SAM
GWC93_RS02980	COG1262	PFAM Formylglycine-generating sulfatase enzyme
GWC93_RS02990	COG3716	PTS system mannose fructose sorbose family IID component
GWC93_RS03000	COG1609	Transcriptional regulator
GWC93_RS03035	COG2267	carboxylic ester hydrolase activity
GWC93_RS03050	COG1378	Sugar-specific transcriptional regulator TrmB
GWC93_RS03080	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GWC93_RS03085	COG1053	succinate dehydrogenase
GWC93_RS03105	COG1131	(ABC) transporter
GWC93_RS03145	COG2814	Major facilitator Superfamily
GWC93_RS03165	COG1879	ABC-type sugar transport system periplasmic component
GWC93_RS03170	COG1172	Belongs to the binding-protein-dependent transport system permease family
GWC93_RS03185	COG1609	Transcriptional regulator
GWC93_RS03195	COG0531	amino acid
GWC93_RS03200	COG0351	phosphomethylpyrimidine kinase
GWC93_RS03220	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
GWC93_RS03230	COG1129	ABC transporter
GWC93_RS03255	COG4166	transmembrane transport
GWC93_RS03260	COG2195	Cleaves the N-terminal amino acid of tripeptides
GWC93_RS03270	COG1363	Peptidase, m42
GWC93_RS03275	COG1447	Phosphotransferase system cellobiose-specific component IIA
GWC93_RS03280	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GWC93_RS03285	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GWC93_RS03290	COG0006	proline dipeptidase activity
GWC93_RS03295	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
GWC93_RS03305	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
GWC93_RS03305	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GWC93_RS03310	COG3716	PTS system mannose fructose sorbose family IID component
GWC93_RS03315	COG3715	PTS system
GWC93_RS03320	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GWC93_RS03335	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
GWC93_RS03340	COG2222	sugar isomerase
GWC93_RS03345	COG2188	Transcriptional regulator
GWC93_RS03350	COG1482	cell wall glycoprotein biosynthetic process
GWC93_RS03355	COG3064	Membrane
GWC93_RS03355	COG3583	domain protein
GWC93_RS03355	COG3525	Glycosyl hydrolase, family 20, catalytic domain
GWC93_RS03365	COG2182	Extracellular solute-binding protein
GWC93_RS03385	COG0446	pyridine nucleotide-disulphide oxidoreductase
GWC93_RS03410	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
GWC93_RS03415	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
GWC93_RS03425	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GWC93_RS03455	COG0683	leucine binding
GWC93_RS03475	COG3118	belongs to the thioredoxin family
GWC93_RS03500	COG0488	(ABC) transporter
GWC93_RS03525	COG1216	Glycosyl transferase, family 2
GWC93_RS03540	COG1114	Component of the transport system for branched-chain amino acids
GWC93_RS03545	COG1316	TRANSCRIPTIONal
GWC93_RS03550	COG1164	Oligoendopeptidase f
GWC93_RS03555	COG2084	Dehydrogenase
GWC93_RS03570	COG1121	(ABC) transporter
GWC93_RS03580	COG2610	gluconate transmembrane transporter activity
GWC93_RS03590	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
GWC93_RS03595	COG1737	Transcriptional regulator
GWC93_RS03600	COG1942	4-Oxalocrotonate Tautomerase
GWC93_RS03605	COG0191	fructose-bisphosphate aldolase activity
GWC93_RS03615	COG0673	inositol 2-dehydrogenase activity
GWC93_RS03620	COG0673	inositol 2-dehydrogenase activity
GWC93_RS03625	COG3962	Belongs to the TPP enzyme family
GWC93_RS03630	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GWC93_RS03635	COG3718	enzyme involved in inositol metabolism
GWC93_RS03640	COG1012	belongs to the aldehyde dehydrogenase family
GWC93_RS03645	COG2814	Major facilitator Superfamily
GWC93_RS03650	COG1349	DNA-binding transcription factor activity
GWC93_RS03655	COG0656	L-ascorbic acid biosynthetic process
GWC93_RS03660	COG1794	racemase activity, acting on amino acids and derivatives
GWC93_RS03670	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
GWC93_RS03675	COG1686	Belongs to the peptidase S11 family
GWC93_RS03695	COG0516	GMP reductase activity
GWC93_RS03695	COG0517	IMP dehydrogenase activity
GWC93_RS03705	COG0012	GTP binding
GWC93_RS03710	COG4481	Protein conserved in bacteria
GWC93_RS03715	COG1475	DNA binding
GWC93_RS03720	COG1192	Involved in chromosome partitioning
GWC93_RS03740	COG3442	glutamine amidotransferase
GWC93_RS03770	COG1302	Protein conserved in bacteria
GWC93_RS03785	COG2261	transglycosylase associated protein
GWC93_RS03795	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GWC93_RS03810	COG0716	FMN binding
GWC93_RS03850	COG0446	pyridine nucleotide-disulphide oxidoreductase
GWC93_RS03860	COG1396	sequence-specific DNA binding
GWC93_RS03865	COG1132	(ABC) transporter
GWC93_RS03885	COG1131	(ABC) transporter
GWC93_RS03905	COG4166	transmembrane transport
GWC93_RS03910	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
GWC93_RS03915	COG0477	Major facilitator Superfamily
GWC93_RS03925	COG1511	domain protein
GWC93_RS03925	COG1511	domain protein
GWC93_RS03950	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
GWC93_RS04010	COG0346	lactoylglutathione lyase activity
GWC93_RS04030	COG0446	pyridine nucleotide-disulphide oxidoreductase
GWC93_RS04050	COG4521	taurine ABC transporter
GWC93_RS04055	COG1116	anion transmembrane transporter activity
GWC93_RS04070	COG2252	PERMEase
GWC93_RS04105	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
GWC93_RS04170	COG1328	CTP reductase activity
GWC93_RS04180	COG1131	(ABC) transporter
GWC93_RS04190	COG3620	sequence-specific DNA binding
GWC93_RS04195	COG0583	DNA-binding transcription factor activity
GWC93_RS04200	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
GWC93_RS04205	COG0640	Transcriptional regulator
GWC93_RS04210	COG2217	Heavy metal translocating P-type atpase
GWC93_RS04230	COG0577	efflux transmembrane transporter activity
GWC93_RS04230	COG1136	(ABC) transporter
GWC93_RS04235	COG1309	transcriptional regulator
GWC93_RS04240	COG1737	Transcriptional regulator
GWC93_RS04245	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
GWC93_RS04260	COG0305	Participates in initiation and elongation during chromosome replication
GWC93_RS04305	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
GWC93_RS04310	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
GWC93_RS04315	COG0527	aspartate kinase activity
GWC93_RS04320	COG0019	diaminopimelate decarboxylase activity
GWC93_RS04340	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
GWC93_RS04365	COG1131	(ABC) transporter
GWC93_RS04400	COG2814	Major facilitator Superfamily
GWC93_RS04415	COG0134	indole-3-glycerol-phosphate synthase activity
GWC93_RS04420	COG0135	phosphoribosylanthranilate isomerase activity
GWC93_RS04425	COG0133	tryptophan synthase activity
GWC93_RS04430	COG0159	tryptophan synthase activity
GWC93_RS04435	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GWC93_RS04445	COG2217	Heavy metal translocating P-type atpase
GWC93_RS04485	COG1732	Glycine betaine
GWC93_RS04500	COG1309	transcriptional regulator
GWC93_RS04505	COG1033	growth of symbiont in host cell
GWC93_RS04505	COG2409	Drug exporters of the RND superfamily
GWC93_RS04515	COG2814	Major facilitator Superfamily
GWC93_RS04520	COG1132	(ABC) transporter
GWC93_RS04540	COG0800	Aldolase
GWC93_RS04655	COG3409	Peptidoglycan-binding domain 1 protein
GWC93_RS04675	COG0561	phosphatase activity
GWC93_RS04695	COG3942	CHAP domain
GWC93_RS04735	COG1294	oxidase, subunit
GWC93_RS04740	COG1271	oxidase subunit
GWC93_RS04750	COG0629	single-stranded DNA binding
GWC93_RS04765	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
GWC93_RS04775	COG0187	DNA topoisomerase II activity
GWC93_RS04785	COG2501	S4 domain
GWC93_RS04790	COG0592	DNA-directed DNA polymerase activity
GWC93_RS04810	COG0706	membrane insertase activity
GWC93_RS04845	COG1473	amidohydrolase
GWC93_RS04850	COG0371	Dehydrogenase
GWC93_RS04870	COG1263	PTS System
GWC93_RS04870	COG2190	(PTS) system
GWC93_RS04870	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GWC93_RS04875	COG2723	6-phospho-beta-galactosidase activity
GWC93_RS04885	COG0577	efflux transmembrane transporter activity
GWC93_RS04890	COG0577	efflux transmembrane transporter activity
GWC93_RS04890	COG1136	(ABC) transporter
GWC93_RS04905	COG0561	phosphatase activity
GWC93_RS04915	COG2213	PTS system mannitol-specific
GWC93_RS04925	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
GWC93_RS04945	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
GWC93_RS04955	COG3711	transcriptional antiterminator
GWC93_RS04960	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GWC93_RS04960	COG1263	PTS System
GWC93_RS04960	COG2190	(PTS) system
GWC93_RS04965	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GWC93_RS04965	COG1263	PTS System
GWC93_RS05010	COG4565	transcriptional regulatory protein
GWC93_RS05015	COG3290	protein histidine kinase activity
GWC93_RS05020	COG3493	citrate carrier protein
GWC93_RS05045	COG0561	phosphatase activity
GWC93_RS05050	COG0110	maltose O-acetyltransferase activity
GWC93_RS05055	COG0438	transferase activity, transferring glycosyl groups
GWC93_RS05060	COG1305	Transglutaminase-like
GWC93_RS05070	COG0714	Associated with various cellular activities
GWC93_RS05085	COG0765	amino acid transport
GWC93_RS05090	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GWC93_RS05100	COG3001	Fructosamine kinase
GWC93_RS05105	COG4133	protoheme IX ABC transporter activity
GWC93_RS05145	COG1126	abc transporter atp-binding protein
GWC93_RS05150	COG0765	amino acid transport
GWC93_RS05180	COG3715	PTS system
GWC93_RS05185	COG3716	PTS system mannose fructose sorbose family IID component
GWC93_RS05195	COG0667	Aldo Keto reductase
GWC93_RS05200	COG2807	transmembrane transport
GWC93_RS05205	COG2814	Major facilitator Superfamily
GWC93_RS05210	COG1335	isochorismatase
GWC93_RS05230	COG1447	Phosphotransferase system cellobiose-specific component IIA
GWC93_RS05235	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GWC93_RS05240	COG2188	Transcriptional regulator
GWC93_RS05245	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GWC93_RS05270	COG0765	amino acid transport
GWC93_RS05275	COG0596	Alpha beta hydrolase
GWC93_RS05280	COG0745	RESPONSE REGULATOR receiver
GWC93_RS05285	COG5002	protein histidine kinase activity
GWC93_RS05300	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
GWC93_RS05310	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GWC93_RS05325	COG2217	Heavy metal translocating P-type atpase
GWC93_RS05335	COG4166	transmembrane transport
GWC93_RS05350	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
GWC93_RS05375	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GWC93_RS05380	COG0789	Transcriptional regulator
GWC93_RS05390	COG2365	Tyrosine phosphatase family
GWC93_RS05395	COG0604	alcohol dehydrogenase
GWC93_RS05420	COG2076	Multidrug Resistance protein
GWC93_RS05430	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
GWC93_RS05445	COG3716	PTS system mannose fructose sorbose family IID component
GWC93_RS05450	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GWC93_RS05455	COG1737	Transcriptional regulator
GWC93_RS05460	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
GWC93_RS05470	COG4948	Mandelate Racemase Muconate Lactonizing
GWC93_RS05485	COG1335	isochorismatase
GWC93_RS05490	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
GWC93_RS05495	COG3842	ATPase activity
GWC93_RS05505	COG0395	ABC-type sugar transport system, permease component
GWC93_RS05515	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
GWC93_RS05520	COG0584	glycerophosphoryl diester phosphodiesterase
GWC93_RS05550	COG0456	acetyltransferase
GWC93_RS05555	COG0477	Major facilitator Superfamily
GWC93_RS05570	COG2188	Transcriptional regulator
GWC93_RS05575	COG0191	fructose-bisphosphate aldolase activity
GWC93_RS05590	COG3775	system Galactitol-specific IIC component
GWC93_RS05595	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
GWC93_RS05605	COG3711	transcriptional antiterminator
GWC93_RS05605	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GWC93_RS05615	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GWC93_RS05615	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
GWC93_RS05625	COG3716	PTS system mannose fructose sorbose family IID component
GWC93_RS05630	COG1063	alcohol dehydrogenase
GWC93_RS05635	COG1070	Carbohydrate kinase
GWC93_RS05660	COG2188	Transcriptional regulator
GWC93_RS05665	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GWC93_RS05670	COG1446	asparaginase
GWC93_RS05680	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
GWC93_RS05685	COG1349	DNA-binding transcription factor activity
GWC93_RS05690	COG1063	alcohol dehydrogenase
GWC93_RS05700	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GWC93_RS05705	COG3715	PTS system
GWC93_RS05710	COG3716	PTS system mannose fructose sorbose family IID component
GWC93_RS05725	COG1063	alcohol dehydrogenase
GWC93_RS05740	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GWC93_RS05755	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
GWC93_RS05760	COG1349	DNA-binding transcription factor activity
GWC93_RS05765	COG3623	hexulose-6-phosphate isomerase
GWC93_RS05770	COG0561	phosphatase activity
GWC93_RS05780	COG1263	PTS System
GWC93_RS05780	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GWC93_RS05780	COG2190	(PTS) system
GWC93_RS05785	COG1609	Transcriptional regulator
GWC93_RS05790	COG2723	6-phospho-beta-galactosidase activity
GWC93_RS05800	COG1263	PTS System
GWC93_RS05800	COG2190	(PTS) system
GWC93_RS05800	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GWC93_RS05810	COG3711	transcriptional antiterminator
GWC93_RS05810	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GWC93_RS05820	COG3730	PTS system glucitol sorbitol-specific
GWC93_RS05825	COG3732	PTS system glucitol sorbitol-specific
GWC93_RS05870	COG3964	amidohydrolase
GWC93_RS05890	COG0800	Aldolase
GWC93_RS05895	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GWC93_RS05920	COG2204	response regulator
GWC93_RS05935	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
GWC93_RS05960	COG3775	system Galactitol-specific IIC component
GWC93_RS05965	COG3414	Phosphotransferase system galactitol-specific IIB component
GWC93_RS06005	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GWC93_RS06005	COG1263	PTS System
GWC93_RS06005	COG2190	(PTS) system
GWC93_RS06015	COG3711	transcriptional antiterminator
GWC93_RS06045	COG1263	PTS System
GWC93_RS06045	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GWC93_RS06055	COG0745	RESPONSE REGULATOR receiver
GWC93_RS06060	COG0586	Pfam SNARE associated Golgi protein
GWC93_RS06070	COG0463	Glycosyl transferase, family 2
GWC93_RS06095	COG0366	Alpha amylase catalytic
GWC93_RS06105	COG1349	DNA-binding transcription factor activity
GWC93_RS06120	COG3775	system Galactitol-specific IIC component
GWC93_RS06135	COG2188	Transcriptional regulator
GWC93_RS06140	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GWC93_RS06155	COG1940	carbohydrate kinase activity
GWC93_RS06160	COG2723	6-phospho-beta-galactosidase activity
GWC93_RS06170	COG1447	Phosphotransferase system cellobiose-specific component IIA
GWC93_RS06175	COG3716	PTS system mannose fructose sorbose family IID component
GWC93_RS06180	COG3715	PTS system
GWC93_RS06185	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GWC93_RS06185	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
GWC93_RS06205	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
GWC93_RS06215	COG1105	Belongs to the carbohydrate kinase PfkB family
GWC93_RS06220	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GWC93_RS06220	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GWC93_RS06220	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GWC93_RS06235	COG1811	Na channel or pump
GWC93_RS06240	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
GWC93_RS06245	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GWC93_RS06260	COG0561	phosphatase activity
GWC93_RS06265	COG0588	phosphoglycerate mutase activity
GWC93_RS06290	COG0561	phosphatase activity
GWC93_RS06295	COG0667	Aldo Keto reductase
GWC93_RS06300	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
GWC93_RS06310	COG1418	mRNA catabolic process
GWC93_RS06335	COG3973	AAA domain
GWC93_RS06340	COG1174	glycine betaine transport
GWC93_RS06350	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GWC93_RS06355	COG0577	efflux transmembrane transporter activity
GWC93_RS06355	COG1136	(ABC) transporter
GWC93_RS06365	COG1704	LemA family
GWC93_RS06370	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
GWC93_RS06375	COG0534	Mate efflux family protein
GWC93_RS06385	COG2226	methyltransferase
GWC93_RS06390	COG4989	oxidoreductase activity
GWC93_RS06400	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
GWC93_RS06405	COG0248	Ppx GppA phosphatase
GWC93_RS06410	COG4086	secreted protein
GWC93_RS06420	COG1881	PFAM PEBP family protein
GWC93_RS06430	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
GWC93_RS06450	COG1801	Protein of unknown function DUF72
GWC93_RS06460	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GWC93_RS06460	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GWC93_RS06475	COG3290	protein histidine kinase activity
GWC93_RS06490	COG3684	Belongs to the aldolase LacD family
GWC93_RS06500	COG0084	hydrolase, TatD family'
GWC93_RS06505	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
GWC93_RS06510	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
GWC93_RS06515	COG4466	Protein conserved in bacteria
GWC93_RS06520	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
GWC93_RS06530	COG0390	transport system, permease component
GWC93_RS06535	COG4619	ABC transporter
GWC93_RS06540	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
GWC93_RS06550	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
GWC93_RS06555	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
GWC93_RS06585	COG1078	dGTPase activity
GWC93_RS06590	COG0095	Lipoate-protein ligase
GWC93_RS06610	COG0504	CTP synthase activity
GWC93_RS06615	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
GWC93_RS06650	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
GWC93_RS06675	COG2337	Toxic component of a toxin-antitoxin (TA) module
GWC93_RS06680	COG4708	membrane
GWC93_RS06685	COG0067	glutamate synthase
GWC93_RS06685	COG0069	glutamate synthase activity
GWC93_RS06685	COG0070	glutamate synthase
GWC93_RS06690	COG0493	'glutamate synthase
GWC93_RS06695	COG1376	ErfK ybiS ycfS ynhG family protein
GWC93_RS06715	COG0039	L-malate dehydrogenase activity
GWC93_RS06725	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
GWC93_RS06730	COG2244	polysaccharide biosynthetic process
GWC93_RS06735	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
GWC93_RS06745	COG1098	S1 RNA binding domain
GWC93_RS06750	COG0037	tRNA processing
GWC93_RS06755	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
GWC93_RS06790	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
GWC93_RS06795	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
GWC93_RS06865	COG4463	regulation of RNA biosynthetic process
GWC93_RS06870	COG0542	response to heat
GWC93_RS06915	COG0450	alkyl hydroperoxide reductase
GWC93_RS07025	COG0200	Binds to the 23S rRNA
GWC93_RS07105	COG0789	Transcriptional regulator
GWC93_RS07115	COG1136	(ABC) transporter
GWC93_RS07120	COG0577	efflux transmembrane transporter activity
GWC93_RS07160	COG4555	ABC transporter
GWC93_RS07175	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GWC93_RS07180	COG1116	anion transmembrane transporter activity
GWC93_RS07200	COG3639	organic phosphonate transmembrane transporter activity
GWC93_RS07220	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
GWC93_RS07225	COG0148	phosphopyruvate hydratase activity
GWC93_RS07240	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
GWC93_RS07320	COG1012	belongs to the aldehyde dehydrogenase family
GWC93_RS07325	COG1121	(ABC) transporter
GWC93_RS07330	COG1108	ABC-type Mn2 Zn2 transport systems permease components
GWC93_RS07360	COG2814	Major facilitator Superfamily
GWC93_RS07370	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
GWC93_RS07375	COG1914	H( )-stimulated, divalent metal cation uptake system
GWC93_RS07385	COG0114	fumarate hydratase activity
GWC93_RS07390	COG1902	pentaerythritol trinitrate reductase activity
GWC93_RS07395	COG4221	oxidoreductase activity
GWC93_RS07400	COG4989	oxidoreductase activity
GWC93_RS07420	COG0110	maltose O-acetyltransferase activity
GWC93_RS07485	COG2274	protein secretion by the type I secretion system
GWC93_RS07490	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GWC93_RS07535	COG1695	Transcriptional regulator
GWC93_RS07575	COG3764	Sortase (surface protein transpeptidase)
GWC93_RS07595	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
GWC93_RS07630	COG1304	FMN binding
GWC93_RS07645	COG0588	phosphoglycerate mutase activity
GWC93_RS07650	COG0517	IMP dehydrogenase activity
GWC93_RS07655	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
GWC93_RS07655	COG0574	Belongs to the PEP-utilizing enzyme family
GWC93_RS07665	COG1131	(ABC) transporter
GWC93_RS07695	COG3152	Membrane
GWC93_RS07700	COG2388	GCN5-related N-acetyl-transferase
GWC93_RS07705	COG0756	dUTP diphosphatase activity
GWC93_RS07710	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
GWC93_RS07715	COG4956	integral membrane protein (PIN domain superfamily)
GWC93_RS07750	COG4886	Leucine-rich repeat (LRR) protein
GWC93_RS07750	COG4932	domain protein
GWC93_RS07765	COG4377	Putative membrane peptidase family (DUF2324)
GWC93_RS07770	COG1737	Transcriptional regulator
GWC93_RS07775	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
GWC93_RS07800	COG0277	FAD linked oxidase domain protein
GWC93_RS07810	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
GWC93_RS07815	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GWC93_RS07820	COG3688	RNA-binding protein containing a PIN domain
GWC93_RS07850	COG1131	(ABC) transporter
GWC93_RS07890	COG4939	FMN-binding domain protein
GWC93_RS07920	COG0250	Participates in transcription elongation, termination and antitermination
GWC93_RS07950	COG2096	Adenosyltransferase
GWC93_RS07955	COG5646	InterPro IPR014922
GWC93_RS07965	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
GWC93_RS07980	COG1012	belongs to the aldehyde dehydrogenase family
GWC93_RS07985	COG0477	Major facilitator Superfamily
GWC93_RS08025	COG1609	Transcriptional regulator
GWC93_RS08035	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
GWC93_RS08035	COG0392	lysyltransferase activity
GWC93_RS08040	COG2813	Specifically methylates the guanine in position
GWC93_RS08050	COG0590	tRNA wobble adenosine to inosine editing
GWC93_RS08060	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
GWC93_RS08085	COG3870	Protein conserved in bacteria
GWC93_RS08090	COG0470	DNA polymerase III
GWC93_RS08125	COG1214	PFAM Peptidase M22, glycoprotease
GWC93_RS08130	COG1214	PFAM Peptidase M22, glycoprotease
GWC93_RS08130	COG0456	acetyltransferase
GWC93_RS08140	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GWC93_RS08145	COG0488	(ABC) transporter
GWC93_RS08150	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
GWC93_RS08155	COG1725	Transcriptional regulator
GWC93_RS08160	COG1131	(ABC) transporter
GWC93_RS08170	COG1316	TRANSCRIPTIONal
GWC93_RS08175	COG1266	CAAX protease self-immunity
GWC93_RS08200	COG0531	amino acid
GWC93_RS08225	COG2814	Major facilitator Superfamily
GWC93_RS08230	COG1253	flavin adenine dinucleotide binding
GWC93_RS08240	COG0505	Belongs to the CarA family
GWC93_RS08250	COG2264	protein methyltransferase activity
GWC93_RS08275	COG1063	alcohol dehydrogenase
GWC93_RS08285	COG0789	Transcriptional regulator
GWC93_RS08290	COG1268	BioY protein
GWC93_RS08300	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
GWC93_RS08305	COG2365	Tyrosine phosphatase family
GWC93_RS08320	COG2818	Glycosylase
GWC93_RS08325	COG0697	spore germination
GWC93_RS08350	COG1271	oxidase subunit
GWC93_RS08355	COG1294	oxidase, subunit
GWC93_RS08360	COG4988	ABC transporter
GWC93_RS08365	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
GWC93_RS08395	COG1518	maintenance of DNA repeat elements
GWC93_RS08420	COG1132	(ABC) transporter
GWC93_RS08425	COG1132	(ABC) transporter
GWC93_RS08435	COG1263	PTS System
GWC93_RS08435	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GWC93_RS08435	COG2190	(PTS) system
GWC93_RS08440	COG2723	6-phospho-beta-galactosidase activity
GWC93_RS08455	COG0477	Major facilitator Superfamily
GWC93_RS08475	COG1297	OPT oligopeptide transporter protein
GWC93_RS08515	COG4152	abc transporter atp-binding protein
GWC93_RS08525	COG0142	geranyltranstransferase activity
GWC93_RS08540	COG0367	asparagine synthase
GWC93_RS08560	COG0436	Aminotransferase
GWC93_RS08565	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GWC93_RS08580	COG2268	Band 7 protein
GWC93_RS08585	COG0527	aspartate kinase activity
GWC93_RS08590	COG0460	homoserine dehydrogenase
GWC93_RS08635	COG0028	Belongs to the TPP enzyme family
GWC93_RS08640	COG1597	lipid kinase activity
GWC93_RS08655	COG0628	permease
GWC93_RS08675	COG0588	phosphoglycerate mutase activity
GWC93_RS08680	COG0494	nUDIX hydrolase
GWC93_RS08685	COG1132	(ABC) transporter
GWC93_RS08690	COG1846	Transcriptional regulator
GWC93_RS08730	COG1979	alcohol dehydrogenase
GWC93_RS08735	COG2267	carboxylic ester hydrolase activity
GWC93_RS08740	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
GWC93_RS08750	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GWC93_RS08755	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GWC93_RS08770	COG1028	Short-chain dehydrogenase reductase Sdr
GWC93_RS08775	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GWC93_RS08780	COG0511	ligase activity, forming carbon-carbon bonds
GWC93_RS08790	COG0439	Biotin carboxylase
GWC93_RS08815	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
GWC93_RS08820	COG0702	epimerase
GWC93_RS08830	COG1609	Transcriptional regulator
GWC93_RS08835	COG0366	Alpha amylase catalytic
GWC93_RS08840	COG1263	PTS System
GWC93_RS08840	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GWC93_RS08840	COG2190	(PTS) system
GWC93_RS08895	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GWC93_RS08935	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GWC93_RS08955	COG1447	Phosphotransferase system cellobiose-specific component IIA
GWC93_RS08970	COG1139	Iron-sulfur cluster binding protein
GWC93_RS08980	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
GWC93_RS08985	COG2814	Major facilitator Superfamily
GWC93_RS08990	COG4166	transmembrane transport
GWC93_RS08995	COG0601	transmembrane transport
GWC93_RS09000	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GWC93_RS09005	COG0444	Belongs to the ABC transporter superfamily
GWC93_RS09010	COG4608	Belongs to the ABC transporter superfamily
GWC93_RS09030	COG1028	Short-chain dehydrogenase reductase Sdr
GWC93_RS09035	COG4708	membrane
GWC93_RS09055	COG0489	protein tyrosine kinase activity
GWC93_RS09070	COG1442	glycosyl transferase family 8
GWC93_RS09070	COG1216	Glycosyl transferase, family 2
GWC93_RS09090	COG2244	polysaccharide biosynthetic process
GWC93_RS09100	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
GWC93_RS09105	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
GWC93_RS09115	COG1088	dTDP-glucose 4,6-dehydratase activity
GWC93_RS09120	COG1091	dTDP-4-dehydrorhamnose reductase activity
GWC93_RS09125	COG1316	TRANSCRIPTIONal
GWC93_RS09130	COG4464	protein tyrosine phosphatase activity
GWC93_RS09140	COG1393	Belongs to the ArsC family
GWC93_RS09150	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GWC93_RS09160	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
GWC93_RS09165	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
GWC93_RS09175	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
GWC93_RS09185	COG0058	SHG alpha-glucan phosphorylase activity
GWC93_RS09210	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
GWC93_RS09220	COG0454	-acetyltransferase
GWC93_RS09220	COG0456	acetyltransferase
GWC93_RS09225	COG0194	GDP metabolic process
GWC93_RS09235	COG0735	belongs to the Fur family
GWC93_RS09255	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GWC93_RS09260	COG0765	amino acid transport
GWC93_RS09265	COG0765	amino acid transport
GWC93_RS09275	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
GWC93_RS09300	COG1376	ErfK ybiS ycfS ynhG family protein
GWC93_RS09310	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
GWC93_RS09320	COG3475	LICD family
GWC93_RS09335	COG1216	Glycosyl transferase, family 2
GWC93_RS09345	COG0438	transferase activity, transferring glycosyl groups
GWC93_RS09370	COG0726	polysaccharide deacetylase
GWC93_RS09375	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
GWC93_RS09385	COG0531	amino acid
GWC93_RS09390	COG1136	(ABC) transporter
GWC93_RS09420	COG2267	carboxylic ester hydrolase activity
GWC93_RS09425	COG0475	glutathione-regulated potassium exporter activity
GWC93_RS09425	COG0569	domain protein
GWC93_RS09435	COG3973	AAA domain
GWC93_RS09440	COG1607	acyl-coa hydrolase
GWC93_RS09445	COG4690	dipeptidase activity
GWC93_RS09525	COG0270	DNA (cytosine-5-)-methyltransferase activity
GWC93_RS09545	COG1349	DNA-binding transcription factor activity
GWC93_RS09555	COG5549	protein import
GWC93_RS09555	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GWC93_RS09575	COG1132	(ABC) transporter
GWC93_RS09590	COG0640	Transcriptional regulator
GWC93_RS09600	COG4166	transmembrane transport
GWC93_RS09605	COG0601	transmembrane transport
GWC93_RS09615	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GWC93_RS09625	COG0444	Belongs to the ABC transporter superfamily
GWC93_RS09630	COG4608	Belongs to the ABC transporter superfamily
GWC93_RS09640	COG1136	(ABC) transporter
GWC93_RS09655	COG1131	(ABC) transporter
GWC93_RS09660	COG1725	Transcriptional regulator
GWC93_RS09680	COG2814	Major facilitator Superfamily
GWC93_RS09695	COG1131	(ABC) transporter
GWC93_RS09735	COG2851	Citrate transporter
GWC93_RS09745	COG0511	ligase activity, forming carbon-carbon bonds
GWC93_RS09780	COG3697	Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase
GWC93_RS09780	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
GWC93_RS09795	COG3697	Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase
GWC93_RS09795	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
GWC93_RS09815	COG0564	pseudouridine synthase activity
GWC93_RS09840	COG0519	Catalyzes the synthesis of GMP from XMP
GWC93_RS09850	COG0028	Belongs to the TPP enzyme family
GWC93_RS09865	COG0833	amino acid
GWC93_RS09990	COG0577	efflux transmembrane transporter activity
GWC93_RS09990	COG1136	(ABC) transporter
GWC93_RS10000	COG3104	oligopeptide transport
GWC93_RS10015	COG1506	peptidase
GWC93_RS10015	COG4946	Tricorn protease homolog
GWC93_RS10015	COG0823	Involved in the tonB-independent uptake of proteins
GWC93_RS10020	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
GWC93_RS10030	COG2188	Transcriptional regulator
GWC93_RS10040	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
GWC93_RS10075	COG4120	Belongs to the binding-protein-dependent transport system permease family
GWC93_RS10080	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
GWC93_RS10085	COG3091	SprT-like family
GWC93_RS10105	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GWC93_RS10130	COG0183	Belongs to the thiolase family
GWC93_RS10140	COG3425	synthase
GWC93_RS10145	COG0028	Belongs to the TPP enzyme family
GWC93_RS10150	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GWC93_RS10155	COG1447	Phosphotransferase system cellobiose-specific component IIA
GWC93_RS10165	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GWC93_RS10170	COG2723	6-phospho-beta-galactosidase activity
GWC93_RS10175	COG2188	Transcriptional regulator
GWC93_RS10185	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GWC93_RS10205	COG3557	Belongs to the UPF0374 family
GWC93_RS10220	COG0628	permease
GWC93_RS10225	COG1253	flavin adenine dinucleotide binding
GWC93_RS10240	COG0542	response to heat
GWC93_RS10250	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
GWC93_RS10260	COG2814	Major facilitator Superfamily
GWC93_RS10270	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
GWC93_RS10275	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
GWC93_RS10285	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
GWC93_RS10305	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
GWC93_RS10310	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
GWC93_RS10320	COG0151	Belongs to the GarS family
GWC93_RS10330	COG3682	Transcriptional regulator
GWC93_RS10335	COG2217	Heavy metal translocating P-type atpase
GWC93_RS10345	COG0642	Histidine kinase
GWC93_RS10350	COG0745	RESPONSE REGULATOR receiver
GWC93_RS10355	COG1136	(ABC) transporter
GWC93_RS10370	COG1234	tRNA 3'-trailer cleavage
GWC93_RS10375	COG1393	Belongs to the ArsC family
GWC93_RS10395	COG0167	dihydroorotate dehydrogenase activity
GWC93_RS10415	COG0018	arginyl-trna synthetase
GWC93_RS10420	COG1438	arginine binding
GWC93_RS10425	COG0564	pseudouridine synthase activity
GWC93_RS10430	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GWC93_RS10445	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GWC93_RS10455	COG0537	adenosine 5'-monophosphoramidase activity
GWC93_RS10460	COG1131	(ABC) transporter
GWC93_RS10485	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GWC93_RS10490	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GWC93_RS10495	COG1674	ftsk spoiiie
GWC93_RS10505	COG0670	Belongs to the BI1 family
GWC93_RS10510	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GWC93_RS10510	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GWC93_RS10515	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
GWC93_RS10520	COG0237	dephospho-CoA kinase activity
GWC93_RS10530	COG3611	Membrane attachment protein
GWC93_RS10535	COG1484	DNA-dependent DNA replication
GWC93_RS10565	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
GWC93_RS10590	COG0400	carboxylic ester hydrolase activity
GWC93_RS10600	COG0346	lactoylglutathione lyase activity
GWC93_RS10605	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
GWC93_RS10610	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
GWC93_RS10615	COG1534	Rna-binding protein
GWC93_RS10620	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
GWC93_RS10630	COG0799	negative regulation of ribosome biogenesis
GWC93_RS10635	COG2226	methyltransferase
GWC93_RS10655	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
GWC93_RS10660	COG0745	RESPONSE REGULATOR receiver
GWC93_RS10665	COG5002	protein histidine kinase activity
GWC93_RS10670	COG0706	membrane insertase activity
GWC93_RS10680	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GWC93_RS10690	COG1733	regulation of RNA biosynthetic process
GWC93_RS10700	COG0072	phenylalanine-tRNA ligase activity
GWC93_RS10705	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
GWC93_RS10710	COG0572	uridine kinase
GWC93_RS10715	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
GWC93_RS10730	COG2197	response regulator
GWC93_RS10735	COG4841	protein insertion into membrane
GWC93_RS10745	COG0768	penicillin binding
GWC93_RS10750	COG0705	Rhomboid family
GWC93_RS10750	COG0457	Tetratricopeptide repeat
GWC93_RS10760	COG1940	carbohydrate kinase activity
GWC93_RS10765	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GWC93_RS10780	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
GWC93_RS10785	COG1982	Orn Lys Arg decarboxylase major
GWC93_RS10790	COG0789	Transcriptional regulator
GWC93_RS10820	COG0261	This protein binds to 23S rRNA in the presence of protein L20
GWC93_RS10825	COG2868	ribosomal protein
GWC93_RS10830	COG0211	Belongs to the bacterial ribosomal protein bL27 family
GWC93_RS10835	COG0006	proline dipeptidase activity
GWC93_RS10840	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
GWC93_RS10845	COG1302	Protein conserved in bacteria
GWC93_RS10865	COG1722	exodeoxyribonuclease VII activity
GWC93_RS10870	COG0142	geranyltranstransferase activity
GWC93_RS10875	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
GWC93_RS10880	COG1438	arginine binding
GWC93_RS10885	COG0497	DNA recombination
GWC93_RS10900	COG0194	GDP metabolic process
GWC93_RS10910	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
GWC93_RS10915	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
GWC93_RS10925	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
GWC93_RS10925	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
GWC93_RS10935	COG2815	serine threonine protein kinase
GWC93_RS10935	COG0515	serine threonine protein kinase
GWC93_RS10940	COG1162	GTPase activity
GWC93_RS10945	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
GWC93_RS10950	COG1564	THIamine pyrophosphokinase
GWC93_RS10965	COG1461	Dihydroxyacetone kinase
GWC93_RS10970	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
GWC93_RS10980	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GWC93_RS10990	COG4608	Belongs to the ABC transporter superfamily
GWC93_RS10995	COG0601	transmembrane transport
GWC93_RS11000	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GWC93_RS11010	COG0571	ribonuclease III activity
GWC93_RS11015	COG1196	nuclear chromosome segregation
GWC93_RS11020	COG0552	protein localization to endoplasmic reticulum
GWC93_RS11035	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
GWC93_RS11045	COG1837	Belongs to the UPF0109 family
GWC93_RS11065	COG4224	UPF0291 protein
GWC93_RS11070	COG3763	UPF0154 protein
GWC93_RS11075	COG1132	(ABC) transporter
GWC93_RS11080	COG1132	(ABC) transporter
GWC93_RS11090	COG0531	amino acid
GWC93_RS11095	COG0204	Acyl-transferase
GWC93_RS11100	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
GWC93_RS11130	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
GWC93_RS11135	COG4589	Belongs to the CDS family
GWC93_RS11140	COG0750	zinc metalloprotease
GWC93_RS11160	COG0195	Participates in both transcription termination and antitermination
GWC93_RS11165	COG2740	Nucleic-acid-binding protein implicated in transcription termination
GWC93_RS11185	COG0861	Integral membrane protein TerC family
GWC93_RS11195	COG0196	riboflavin kinase activity
GWC93_RS11200	COG0635	Involved in the biosynthesis of porphyrin-containing compound
GWC93_RS11210	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
GWC93_RS11225	COG1132	(ABC) transporter
GWC93_RS11255	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
GWC93_RS11255	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
GWC93_RS11265	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
GWC93_RS11320	COG0438	transferase activity, transferring glycosyl groups
GWC93_RS11325	COG0673	inositol 2-dehydrogenase activity
GWC93_RS11360	COG2094	Belongs to the DNA glycosylase MPG family
GWC93_RS11375	COG1385	rRNA (uridine-N3-)-methyltransferase activity
GWC93_RS11385	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
GWC93_RS11400	COG0860	N-Acetylmuramoyl-L-alanine amidase
GWC93_RS11400	COG3103	Sh3 type 3 domain protein
GWC93_RS11400	COG4991	sh3 domain protein
GWC93_RS11410	COG1131	(ABC) transporter
GWC93_RS11440	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GWC93_RS11445	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GWC93_RS11450	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
GWC93_RS11465	COG1610	YqeY-like protein
GWC93_RS11470	COG1702	phosphate starvation-inducible protein PhoH
GWC93_RS11485	COG0295	cytidine deaminase activity
GWC93_RS11495	COG1381	Involved in DNA repair and RecF pathway recombination
GWC93_RS11520	COG0358	DNA primase activity
GWC93_RS11525	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
GWC93_RS11530	COG2384	SAM-dependent methyltransferase
GWC93_RS11535	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
GWC93_RS11540	COG1942	4-Oxalocrotonate Tautomerase
GWC93_RS11545	COG2151	metal-sulfur cluster biosynthetic enzyme
GWC93_RS11560	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
GWC93_RS11560	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
GWC93_RS11590	COG1199	ATP-dependent helicase activity
GWC93_RS11590	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
GWC93_RS11600	COG0436	Aminotransferase
GWC93_RS11615	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
GWC93_RS11620	COG2131	deaminase
GWC93_RS11625	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GWC93_RS11650	COG0116	Belongs to the methyltransferase superfamily
GWC93_RS11665	COG0095	Lipoate-protein ligase
GWC93_RS11670	COG3590	peptidase
GWC93_RS11675	COG0583	DNA-binding transcription factor activity
GWC93_RS11680	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GWC93_RS11685	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GWC93_RS11690	COG1393	Belongs to the ArsC family
GWC93_RS11705	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GWC93_RS11715	COG0328	RNA-DNA hybrid ribonuclease activity
GWC93_RS11730	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
GWC93_RS11735	COG0564	pseudouridine synthase activity
GWC93_RS11740	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
GWC93_RS11745	COG2233	PERMEase
GWC93_RS11755	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
GWC93_RS11760	COG0505	Belongs to the CarA family
GWC93_RS11775	COG0284	orotidine-5'-phosphate decarboxylase activity
GWC93_RS11780	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
GWC93_RS11785	COG0280	phosphate acetyltransferase
GWC93_RS11790	COG3426	butyrate kinase activity
GWC93_RS11795	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GWC93_RS11800	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
GWC93_RS11805	COG0022	dehydrogenase e1 component
GWC93_RS11810	COG0508	dehydrogenase complex catalyzes the overall conversion of
GWC93_RS11815	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
GWC93_RS11830	COG1293	RNA-binding protein homologous to eukaryotic snRNP
GWC93_RS11835	COG1307	EDD domain protein, DegV family
GWC93_RS11840	COG0494	nUDIX hydrolase
GWC93_RS11845	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
GWC93_RS11860	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
GWC93_RS11895	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
GWC93_RS11900	COG0778	Nitroreductase
GWC93_RS11920	COG0745	RESPONSE REGULATOR receiver
GWC93_RS11925	COG5002	protein histidine kinase activity
GWC93_RS11930	COG1136	(ABC) transporter
GWC93_RS11935	COG0577	efflux transmembrane transporter activity
GWC93_RS11945	COG4974	Belongs to the 'phage' integrase family
GWC93_RS11950	COG1227	inorganic diphosphatase activity
GWC93_RS11955	COG0583	DNA-binding transcription factor activity
GWC93_RS11960	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
GWC93_RS11965	COG1882	Formate acetyltransferase
GWC93_RS11970	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
GWC93_RS11975	COG0187	DNA topoisomerase II activity
GWC93_RS11990	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
GWC93_RS12010	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
GWC93_RS12015	COG0758	DNA mediated transformation
GWC93_RS12060	COG0793	Belongs to the peptidase S41A family
GWC93_RS12060	COG3409	Peptidoglycan-binding domain 1 protein
GWC93_RS12070	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GWC93_RS12080	COG2755	lipolytic protein G-D-S-L family
GWC93_RS12085	COG1307	EDD domain protein, DegV family
GWC93_RS12090	COG1272	protein, Hemolysin III
GWC93_RS12105	COG0488	(ABC) transporter
GWC93_RS12120	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GWC93_RS12125	COG0457	Tetratricopeptide repeat
GWC93_RS12140	COG0539	negative regulation of cytoplasmic translation
GWC93_RS12155	COG0514	ATP-dependent DNA helicase (RecQ)
GWC93_RS12170	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
GWC93_RS12175	COG1187	pseudouridine synthase activity
GWC93_RS12180	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
GWC93_RS12185	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
GWC93_RS12190	COG0456	acetyltransferase
GWC93_RS12200	COG2996	Protein conserved in bacteria
GWC93_RS12220	COG0587	DNA-directed DNA polymerase activity
GWC93_RS12235	COG0737	Belongs to the 5'-nucleotidase family
GWC93_RS12250	COG0542	response to heat
GWC93_RS12260	COG0300	oxidoreductase activity
GWC93_RS12270	COG2755	lipolytic protein G-D-S-L family
GWC93_RS12270	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
GWC93_RS12280	COG1349	DNA-binding transcription factor activity
GWC93_RS12285	COG1105	Belongs to the carbohydrate kinase PfkB family
GWC93_RS12290	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GWC93_RS12290	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GWC93_RS12290	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GWC93_RS12300	COG1126	abc transporter atp-binding protein
GWC93_RS12305	COG0765	amino acid transport
GWC93_RS12320	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
GWC93_RS12330	COG1132	(ABC) transporter
GWC93_RS12345	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
GWC93_RS12390	COG1466	dna polymerase III delta subunit
GWC93_RS12395	COG2333	competence protein COMEC
GWC93_RS12395	COG0658	competence protein
GWC93_RS12405	COG3480	Lon protease (S16) C-terminal proteolytic domain
GWC93_RS12415	COG0742	ribosomal rna small subunit methyltransferase
GWC93_RS12420	COG4471	UPF0298 protein
GWC93_RS12425	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
GWC93_RS12430	COG0772	Belongs to the SEDS family
GWC93_RS12435	COG1217	gtp-binding protein TYPA
GWC93_RS12440	COG0483	inositol monophosphate 1-phosphatase activity
GWC93_RS12505	COG1597	lipid kinase activity
GWC93_RS12515	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
GWC93_RS12535	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
GWC93_RS12545	COG1104	cysteine desulfurase activity
GWC93_RS12560	COG0494	nUDIX hydrolase
GWC93_RS12570	COG3853	Toxic anion resistance protein (TelA)
GWC93_RS12575	COG2814	Major facilitator Superfamily
GWC93_RS12585	COG1278	Cold shock
GWC93_RS12595	COG3599	regulation of cell shape
GWC93_RS12615	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
GWC93_RS12645	COG0768	penicillin binding
GWC93_RS12660	COG2001	Belongs to the MraZ family
GWC93_RS12675	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GWC93_RS12680	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GWC93_RS12690	COG0765	amino acid transport
GWC93_RS12695	COG2894	cell division
GWC93_RS12700	COG0850	regulation of cytokinetic process
GWC93_RS12710	COG1792	Involved in formation and maintenance of cell shape
GWC93_RS12715	COG1077	Cell shape determining protein MreB Mrl
GWC93_RS12720	COG2003	Belongs to the UPF0758 family
GWC93_RS12735	COG0525	valine-tRNA ligase activity
GWC93_RS12740	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
GWC93_RS12750	COG1104	cysteine desulfurase activity
GWC93_RS12755	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
GWC93_RS12760	COG1956	GAF domain-containing protein
GWC93_RS12785	COG3620	sequence-specific DNA binding
GWC93_RS12790	COG2183	response to ionizing radiation
GWC93_RS12825	COG0789	Transcriptional regulator
GWC93_RS12835	COG1131	(ABC) transporter
GWC93_RS12845	COG4585	Histidine kinase
GWC93_RS12850	COG2197	response regulator
GWC93_RS12855	COG1307	EDD domain protein, DegV family
GWC93_RS12870	COG0454	-acetyltransferase
GWC93_RS12905	COG0583	DNA-binding transcription factor activity
GWC93_RS12920	COG0745	RESPONSE REGULATOR receiver
GWC93_RS12925	COG2205	protein histidine kinase activity
GWC93_RS12930	COG4166	transmembrane transport
GWC93_RS12940	COG1428	Deoxynucleoside kinase
GWC93_RS12950	COG1028	Short-chain dehydrogenase reductase Sdr
GWC93_RS12965	COG1760	l-serine dehydratase
GWC93_RS12970	COG1760	l-serine dehydratase
GWC93_RS12980	COG5506	Protein of unknown function (DUF1694)
GWC93_RS12985	COG0189	ligase activity
GWC93_RS12985	COG2918	glutathione biosynthetic process
GWC93_RS12990	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
GWC93_RS13005	COG0589	response to stress
GWC93_RS13035	COG0719	Fe-S assembly protein
GWC93_RS13040	COG0822	iron-sulfur transferase activity
GWC93_RS13045	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
GWC93_RS13050	COG0719	Fe-S assembly protein
GWC93_RS13060	COG2011	ABC-type metal ion transport system permease component
GWC93_RS13070	COG1464	Belongs to the NlpA lipoprotein family
GWC93_RS13075	COG1464	Belongs to the NlpA lipoprotein family
GWC93_RS13080	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GWC93_RS13085	COG0509	glycine decarboxylation via glycine cleavage system
GWC93_RS13090	COG0772	Belongs to the SEDS family
GWC93_RS13110	COG1077	Cell shape determining protein MreB Mrl
GWC93_RS13155	COG0356	it plays a direct role in the translocation of protons across the membrane
GWC93_RS13170	COG0009	L-threonylcarbamoyladenylate synthase
GWC93_RS13175	COG2890	protein-(glutamine-N5) methyltransferase activity
GWC93_RS13185	COG1435	thymidine kinase activity
GWC93_RS13190	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
GWC93_RS13200	COG2514	catechol 2,3-dioxygenase activity
GWC93_RS13250	COG3548	integral membrane protein
GWC93_RS13255	COG2814	Major facilitator Superfamily
GWC93_RS13270	COG0590	tRNA wobble adenosine to inosine editing
GWC93_RS13530	COG0629	single-stranded DNA binding
GWC93_RS13535	COG3935	DnaD domain protein
GWC93_RS13580	COG1396	sequence-specific DNA binding
GWC93_RS13615	COG0582	viral genome integration into host DNA
GWC93_RS13625	COG4975	Glucose uptake
GWC93_RS13635	COG1368	sulfuric ester hydrolase activity
GWC93_RS13650	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
GWC93_RS13655	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
GWC93_RS13670	COG1705	Flagellar rod assembly protein muramidase FlgJ
GWC93_RS13680	COG1278	Cold shock
GWC93_RS13690	COG4129	membrane
GWC93_RS13700	COG0463	Glycosyl transferase, family 2
GWC93_RS13710	COG4485	Bacterial membrane protein, YfhO
GWC93_RS13715	COG3711	transcriptional antiterminator
GWC93_RS13720	COG1263	PTS System
GWC93_RS13720	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GWC93_RS13720	COG2190	(PTS) system
GWC93_RS13760	COG1210	Utp--glucose-1-phosphate uridylyltransferase
GWC93_RS13780	COG0463	Glycosyl transferase, family 2
GWC93_RS13785	COG0024	Methionine aminopeptidase
GWC93_RS13790	COG0716	FMN binding
GWC93_RS13795	COG1295	ribonuclease BN
GWC93_RS13810	COG2309	aminopeptidase activity
GWC93_RS13815	COG0514	ATP-dependent DNA helicase (RecQ)
GWC93_RS13835	COG1447	Phosphotransferase system cellobiose-specific component IIA
GWC93_RS13845	COG0673	inositol 2-dehydrogenase activity
GWC93_RS13885	COG2814	Major facilitator Superfamily
GWC93_RS13890	COG3590	peptidase
GWC93_RS13895	COG2326	polyphosphate kinase activity
GWC93_RS13900	COG0561	phosphatase activity
GWC93_RS13905	COG2814	Major facilitator Superfamily
GWC93_RS13910	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GWC93_RS13965	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
GWC93_RS13995	COG5002	protein histidine kinase activity
GWC93_RS13995	COG3850	Histidine kinase
GWC93_RS14000	COG0745	RESPONSE REGULATOR receiver
GWC93_RS14015	COG2261	transglycosylase associated protein
GWC93_RS14035	COG4695	Portal protein
GWC93_RS14145	COG1113	amino acid transport
GWC93_RS14155	COG0827	DNA restriction-modification system
GWC93_RS14185	COG1459	type II secretion system
GWC93_RS14190	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
GWC93_RS14210	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
GWC93_RS14240	COG1309	transcriptional regulator
GWC93_RS14245	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
GWC93_RS14260	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
GWC93_RS14265	COG1177	transmembrane transport
GWC93_RS14270	COG1176	ABC-type spermidine putrescine transport system, permease component I
GWC93_RS14280	COG3800	Transcriptional regulator
GWC93_RS14280	COG1396	sequence-specific DNA binding
GWC93_RS14295	COG0708	Exodeoxyribonuclease III
GWC93_RS14305	COG1668	transmembrane transport
GWC93_RS14310	COG4152	abc transporter atp-binding protein
GWC93_RS14315	COG0802	atpase or kinase
GWC93_RS14320	COG0280	phosphate acetyltransferase
GWC93_RS14330	COG0561	phosphatase activity
GWC93_RS14350	COG1175	transmembrane transport
GWC93_RS14355	COG0395	ABC-type sugar transport system, permease component
GWC93_RS14385	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GWC93_RS14400	COG0366	Alpha amylase catalytic
GWC93_RS14405	COG1609	Transcriptional regulator
GWC93_RS14415	COG0557	exoribonuclease II activity
GWC93_RS14425	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
GWC93_RS14465	COG2390	Transcriptional regulator
GWC93_RS14480	COG1846	Transcriptional regulator
GWC93_RS14490	COG0391	Required for morphogenesis under gluconeogenic growth conditions
GWC93_RS14505	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
GWC93_RS14530	COG1136	(ABC) transporter
GWC93_RS14535	COG2205	protein histidine kinase activity
GWC93_RS14540	COG0745	RESPONSE REGULATOR receiver
GWC93_RS14545	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GWC93_RS14550	COG0492	ferredoxin-NADP+ reductase activity
GWC93_RS14560	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
GWC93_RS14570	COG1950	PFAM Membrane protein of
GWC93_RS14585	COG0704	Plays a role in the regulation of phosphate uptake
GWC93_RS14590	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
GWC93_RS14595	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
GWC93_RS14600	COG0581	inorganic phosphate transmembrane transporter activity
GWC93_RS14605	COG0573	inorganic phosphate transmembrane transporter activity
GWC93_RS14615	COG5002	protein histidine kinase activity
GWC93_RS14620	COG0745	RESPONSE REGULATOR receiver
GWC93_RS14630	COG2177	Part of the ABC transporter FtsEX involved in
GWC93_RS14635	COG2884	Cell division ATP-binding protein ftsE
GWC93_RS14660	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
GWC93_RS14665	COG1739	Uncharacterized protein family UPF0029
GWC93_RS14675	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
GWC93_RS14685	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
GWC93_RS14690	COG1426	Protein conserved in bacteria
GWC93_RS14695	COG1028	Short-chain dehydrogenase reductase Sdr
GWC93_RS14700	COG0612	Peptidase, M16
GWC93_RS14705	COG0612	Peptidase, M16
GWC93_RS14710	COG1674	ftsk spoiiie
GWC93_RS14720	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
GWC93_RS14725	COG2226	methyltransferase
GWC93_RS14740	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
GWC93_RS14750	COG2706	6-phosphogluconolactonase activity
GWC93_RS14760	COG3142	Participates in the control of copper homeostasis
GWC93_RS14770	COG0564	pseudouridine synthase activity
GWC93_RS14780	COG2357	RelA SpoT domain protein
GWC93_RS14805	COG3830	Belongs to the UPF0237 family
GWC93_RS14815	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
GWC93_RS14820	COG0386	Belongs to the glutathione peroxidase family
GWC93_RS14825	COG0438	transferase activity, transferring glycosyl groups
GWC93_RS14920	COG0740	serine-type endopeptidase activity
GWC93_RS15035	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
GWC93_RS15230	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
GWC93_RS15235	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
GWC93_RS15240	COG0626	cystathionine gamma-synthase activity
GWC93_RS15245	COG1045	serine acetyltransferase
GWC93_RS15260	COG4975	Glucose uptake
GWC93_RS15275	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
GWC93_RS15300	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
GWC93_RS15310	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GWC93_RS15335	COG3711	transcriptional antiterminator
GWC93_RS15340	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GWC93_RS15340	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GWC93_RS15350	COG1447	Phosphotransferase system cellobiose-specific component IIA
GWC93_RS15360	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
GWC93_RS15360	COG3933	PFAM sigma-54 factor interaction domain-containing protein
GWC93_RS15365	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
GWC93_RS15375	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
GWC93_RS15375	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GWC93_RS15385	COG3716	PTS system mannose fructose sorbose family IID component
GWC93_RS15410	COG2188	Transcriptional regulator
GWC93_RS15415	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GWC93_RS15420	COG3715	PTS system
GWC93_RS15425	COG3716	PTS system mannose fructose sorbose family IID component
GWC93_RS15445	COG1472	Belongs to the glycosyl hydrolase 3 family
GWC93_RS15460	COG1192	Involved in chromosome partitioning
GWC93_RS15545	COG1192	Involved in chromosome partitioning
GWC93_RS15555	COG4282	regulation of fungal-type cell wall biogenesis
GWC93_RS15570	COG2190	(PTS) system
GWC93_RS15570	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GWC93_RS15570	COG1263	PTS System
GWC93_RS15580	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
GWC93_RS15590	COG1263	PTS System
GWC93_RS15590	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GWC93_RS15595	COG2382	esterase
GWC93_RS15630	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
GWC93_RS15630	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GWC93_RS15635	COG3716	PTS system mannose fructose sorbose family IID component
GWC93_RS15670	COG0556	nucleotide-excision repair
GWC93_RS15680	COG3421	Type III restriction
GWC93_RS15685	COG2189	Belongs to the N(4) N(6)-methyltransferase family