locus-tag	class	description
AWC33_RS00015	COG0588	phosphoglycerate mutase activity
AWC33_RS00020	COG0517	IMP dehydrogenase activity
AWC33_RS00025	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AWC33_RS00025	COG0574	Belongs to the PEP-utilizing enzyme family
AWC33_RS00035	COG1131	(ABC) transporter
AWC33_RS00060	COG3152	Membrane
AWC33_RS00065	COG2388	GCN5-related N-acetyl-transferase
AWC33_RS00070	COG0756	dUTP diphosphatase activity
AWC33_RS00075	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
AWC33_RS00080	COG4956	integral membrane protein (PIN domain superfamily)
AWC33_RS00085	COG1131	(ABC) transporter
AWC33_RS00095	COG4886	Leucine-rich repeat (LRR) protein
AWC33_RS00095	COG4932	domain protein
AWC33_RS00110	COG4377	Putative membrane peptidase family (DUF2324)
AWC33_RS00115	COG1737	Transcriptional regulator
AWC33_RS00120	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
AWC33_RS00145	COG0277	FAD linked oxidase domain protein
AWC33_RS00155	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
AWC33_RS00160	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AWC33_RS00165	COG3688	RNA-binding protein containing a PIN domain
AWC33_RS00210	COG4939	FMN-binding domain protein
AWC33_RS00235	COG0250	Participates in transcription elongation, termination and antitermination
AWC33_RS00265	COG2096	Adenosyltransferase
AWC33_RS00295	COG1012	belongs to the aldehyde dehydrogenase family
AWC33_RS00300	COG0477	Major facilitator Superfamily
AWC33_RS00330	COG4974	Belongs to the 'phage' integrase family
AWC33_RS00375	COG1396	sequence-specific DNA binding
AWC33_RS00425	COG0629	single-stranded DNA binding
AWC33_RS00635	COG1609	Transcriptional regulator
AWC33_RS00645	COG0392	lysyltransferase activity
AWC33_RS00645	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
AWC33_RS00650	COG2813	Specifically methylates the guanine in position
AWC33_RS00660	COG0590	tRNA wobble adenosine to inosine editing
AWC33_RS00670	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
AWC33_RS00695	COG3870	Protein conserved in bacteria
AWC33_RS00700	COG0470	DNA polymerase III
AWC33_RS00735	COG1214	PFAM Peptidase M22, glycoprotease
AWC33_RS00740	COG1214	PFAM Peptidase M22, glycoprotease
AWC33_RS00740	COG0456	acetyltransferase
AWC33_RS00750	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AWC33_RS00755	COG0488	(ABC) transporter
AWC33_RS00760	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
AWC33_RS00765	COG1725	Transcriptional regulator
AWC33_RS00770	COG1131	(ABC) transporter
AWC33_RS00780	COG1316	TRANSCRIPTIONal
AWC33_RS00785	COG1266	CAAX protease self-immunity
AWC33_RS00805	COG0531	amino acid
AWC33_RS00835	COG2814	Major facilitator Superfamily
AWC33_RS00840	COG1253	flavin adenine dinucleotide binding
AWC33_RS00850	COG0505	Belongs to the CarA family
AWC33_RS00860	COG2264	protein methyltransferase activity
AWC33_RS00880	COG1063	alcohol dehydrogenase
AWC33_RS00890	COG0789	Transcriptional regulator
AWC33_RS00895	COG1268	BioY protein
AWC33_RS00905	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
AWC33_RS00910	COG2365	Tyrosine phosphatase family
AWC33_RS00925	COG2818	Glycosylase
AWC33_RS00930	COG0697	spore germination
AWC33_RS00960	COG1271	oxidase subunit
AWC33_RS00965	COG1294	oxidase, subunit
AWC33_RS00970	COG4988	ABC transporter
AWC33_RS00975	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
AWC33_RS01020	COG1132	(ABC) transporter
AWC33_RS01025	COG1132	(ABC) transporter
AWC33_RS01035	COG1263	PTS System
AWC33_RS01035	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AWC33_RS01035	COG2190	(PTS) system
AWC33_RS01040	COG2723	6-phospho-beta-galactosidase activity
AWC33_RS01050	COG0477	Major facilitator Superfamily
AWC33_RS01070	COG1297	OPT oligopeptide transporter protein
AWC33_RS01115	COG2826	transposase and inactivated derivatives, IS30 family
AWC33_RS01130	COG0142	geranyltranstransferase activity
AWC33_RS01165	COG0367	asparagine synthase
AWC33_RS01190	COG0436	Aminotransferase
AWC33_RS01195	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AWC33_RS01210	COG2268	Band 7 protein
AWC33_RS01215	COG0527	aspartate kinase activity
AWC33_RS01220	COG0460	homoserine dehydrogenase
AWC33_RS01265	COG0028	Belongs to the TPP enzyme family
AWC33_RS01270	COG1597	lipid kinase activity
AWC33_RS01285	COG0628	permease
AWC33_RS01305	COG0588	phosphoglycerate mutase activity
AWC33_RS01310	COG0494	nUDIX hydrolase
AWC33_RS01315	COG1132	(ABC) transporter
AWC33_RS01320	COG1846	Transcriptional regulator
AWC33_RS01350	COG1979	alcohol dehydrogenase
AWC33_RS01355	COG2267	carboxylic ester hydrolase activity
AWC33_RS01360	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AWC33_RS01370	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AWC33_RS01375	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AWC33_RS01390	COG1028	Short-chain dehydrogenase reductase Sdr
AWC33_RS01395	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AWC33_RS01400	COG0511	ligase activity, forming carbon-carbon bonds
AWC33_RS01410	COG0439	Biotin carboxylase
AWC33_RS01425	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AWC33_RS01430	COG0702	epimerase
AWC33_RS01445	COG1609	Transcriptional regulator
AWC33_RS01450	COG0366	Alpha amylase catalytic
AWC33_RS01455	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AWC33_RS01455	COG1263	PTS System
AWC33_RS01455	COG2190	(PTS) system
AWC33_RS01470	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
AWC33_RS01495	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AWC33_RS01535	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AWC33_RS01555	COG1447	Phosphotransferase system cellobiose-specific component IIA
AWC33_RS01565	COG0247	lactate metabolic process
AWC33_RS01570	COG1139	Iron-sulfur cluster binding protein
AWC33_RS01580	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
AWC33_RS01590	COG2814	Major facilitator Superfamily
AWC33_RS01595	COG4166	transmembrane transport
AWC33_RS01600	COG0601	transmembrane transport
AWC33_RS01605	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AWC33_RS01610	COG0444	Belongs to the ABC transporter superfamily
AWC33_RS01615	COG4608	Belongs to the ABC transporter superfamily
AWC33_RS01635	COG1028	Short-chain dehydrogenase reductase Sdr
AWC33_RS01640	COG4708	membrane
AWC33_RS01655	COG3328	transposase activity
AWC33_RS01665	COG0489	protein tyrosine kinase activity
AWC33_RS01700	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
AWC33_RS01710	COG1316	TRANSCRIPTIONal
AWC33_RS01715	COG4464	protein tyrosine phosphatase activity
AWC33_RS01725	COG1393	Belongs to the ArsC family
AWC33_RS01740	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AWC33_RS01750	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AWC33_RS01755	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
AWC33_RS01765	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
AWC33_RS01775	COG0058	SHG alpha-glucan phosphorylase activity
AWC33_RS01800	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
AWC33_RS01815	COG0194	GDP metabolic process
AWC33_RS01825	COG0735	belongs to the Fur family
AWC33_RS01845	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AWC33_RS01850	COG0765	amino acid transport
AWC33_RS01855	COG0765	amino acid transport
AWC33_RS01865	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
AWC33_RS01905	COG3328	transposase activity
AWC33_RS01910	COG1376	ErfK ybiS ycfS ynhG family protein
AWC33_RS01920	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
AWC33_RS01930	COG3475	LICD family
AWC33_RS01945	COG1216	Glycosyl transferase, family 2
AWC33_RS01955	COG0438	transferase activity, transferring glycosyl groups
AWC33_RS01990	COG0726	polysaccharide deacetylase
AWC33_RS01995	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
AWC33_RS02005	COG0531	amino acid
AWC33_RS02010	COG1136	(ABC) transporter
AWC33_RS02040	COG2267	carboxylic ester hydrolase activity
AWC33_RS02045	COG0569	domain protein
AWC33_RS02045	COG0475	glutathione-regulated potassium exporter activity
AWC33_RS02055	COG3973	AAA domain
AWC33_RS02060	COG1607	acyl-coa hydrolase
AWC33_RS02065	COG4690	dipeptidase activity
AWC33_RS02110	COG5549	protein import
AWC33_RS02110	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AWC33_RS02145	COG1132	(ABC) transporter
AWC33_RS02160	COG0640	Transcriptional regulator
AWC33_RS02170	COG4166	transmembrane transport
AWC33_RS02175	COG0601	transmembrane transport
AWC33_RS02180	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AWC33_RS02190	COG0444	Belongs to the ABC transporter superfamily
AWC33_RS02195	COG4608	Belongs to the ABC transporter superfamily
AWC33_RS02215	COG1131	(ABC) transporter
AWC33_RS02220	COG1725	Transcriptional regulator
AWC33_RS02240	COG2814	Major facilitator Superfamily
AWC33_RS02255	COG1131	(ABC) transporter
AWC33_RS02295	COG2851	Citrate transporter
AWC33_RS02305	COG0511	ligase activity, forming carbon-carbon bonds
AWC33_RS02340	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
AWC33_RS02340	COG3697	Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase
AWC33_RS02355	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
AWC33_RS02355	COG3697	Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase
AWC33_RS02375	COG0564	pseudouridine synthase activity
AWC33_RS02410	COG0028	Belongs to the TPP enzyme family
AWC33_RS02420	COG0833	amino acid
AWC33_RS02515	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
AWC33_RS02560	COG1061	Type III restriction enzyme res subunit
AWC33_RS02640	COG2826	transposase and inactivated derivatives, IS30 family
AWC33_RS02680	COG0740	serine-type endopeptidase activity
AWC33_RS02830	COG1136	(ABC) transporter
AWC33_RS02830	COG0577	efflux transmembrane transporter activity
AWC33_RS02835	COG3104	oligopeptide transport
AWC33_RS02850	COG4946	Tricorn protease homolog
AWC33_RS02850	COG1506	peptidase
AWC33_RS02850	COG0823	Involved in the tonB-independent uptake of proteins
AWC33_RS02855	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
AWC33_RS02860	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
AWC33_RS02865	COG2188	Transcriptional regulator
AWC33_RS02870	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
AWC33_RS02905	COG4120	Belongs to the binding-protein-dependent transport system permease family
AWC33_RS02910	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
AWC33_RS02915	COG3091	SprT-like family
AWC33_RS02935	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AWC33_RS02960	COG0183	Belongs to the thiolase family
AWC33_RS02970	COG3425	synthase
AWC33_RS02975	COG0028	Belongs to the TPP enzyme family
AWC33_RS02985	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AWC33_RS02990	COG1447	Phosphotransferase system cellobiose-specific component IIA
AWC33_RS03015	COG2723	6-phospho-beta-galactosidase activity
AWC33_RS03020	COG2188	Transcriptional regulator
AWC33_RS03030	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AWC33_RS03050	COG3557	Belongs to the UPF0374 family
AWC33_RS03065	COG0628	permease
AWC33_RS03070	COG1253	flavin adenine dinucleotide binding
AWC33_RS03090	COG0542	response to heat
AWC33_RS03100	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AWC33_RS03110	COG2814	Major facilitator Superfamily
AWC33_RS03120	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
AWC33_RS03125	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
AWC33_RS03135	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AWC33_RS03155	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
AWC33_RS03160	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
AWC33_RS03170	COG0151	Belongs to the GarS family
AWC33_RS03175	COG3682	Transcriptional regulator
AWC33_RS03190	COG0642	Histidine kinase
AWC33_RS03195	COG0745	RESPONSE REGULATOR receiver
AWC33_RS03200	COG1136	(ABC) transporter
AWC33_RS03215	COG1234	tRNA 3'-trailer cleavage
AWC33_RS03220	COG1393	Belongs to the ArsC family
AWC33_RS03240	COG0167	dihydroorotate dehydrogenase activity
AWC33_RS03260	COG0018	arginyl-trna synthetase
AWC33_RS03265	COG1438	arginine binding
AWC33_RS03270	COG0564	pseudouridine synthase activity
AWC33_RS03275	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AWC33_RS03290	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AWC33_RS03300	COG0537	adenosine 5'-monophosphoramidase activity
AWC33_RS03305	COG1131	(ABC) transporter
AWC33_RS03330	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AWC33_RS03335	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AWC33_RS03340	COG1674	ftsk spoiiie
AWC33_RS03350	COG0670	Belongs to the BI1 family
AWC33_RS03355	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AWC33_RS03355	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AWC33_RS03360	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
AWC33_RS03365	COG0237	dephospho-CoA kinase activity
AWC33_RS03375	COG3611	Membrane attachment protein
AWC33_RS03380	COG1484	DNA-dependent DNA replication
AWC33_RS03405	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
AWC33_RS03430	COG0400	carboxylic ester hydrolase activity
AWC33_RS03440	COG0346	lactoylglutathione lyase activity
AWC33_RS03445	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
AWC33_RS03450	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
AWC33_RS03455	COG1534	Rna-binding protein
AWC33_RS03460	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
AWC33_RS03470	COG0799	negative regulation of ribosome biogenesis
AWC33_RS03475	COG2226	methyltransferase
AWC33_RS03495	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
AWC33_RS03500	COG0745	RESPONSE REGULATOR receiver
AWC33_RS03505	COG5002	protein histidine kinase activity
AWC33_RS03510	COG0706	membrane insertase activity
AWC33_RS03520	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AWC33_RS03530	COG1733	regulation of RNA biosynthetic process
AWC33_RS03540	COG0072	phenylalanine-tRNA ligase activity
AWC33_RS03545	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
AWC33_RS03550	COG0572	uridine kinase
AWC33_RS03555	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AWC33_RS03565	COG4585	Histidine kinase
AWC33_RS03570	COG2197	response regulator
AWC33_RS03575	COG4841	protein insertion into membrane
AWC33_RS03585	COG0768	penicillin binding
AWC33_RS03590	COG0705	Rhomboid family
AWC33_RS03590	COG0457	Tetratricopeptide repeat
AWC33_RS03600	COG1940	carbohydrate kinase activity
AWC33_RS03605	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AWC33_RS03620	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
AWC33_RS03625	COG1982	Orn Lys Arg decarboxylase major
AWC33_RS03630	COG0789	Transcriptional regulator
AWC33_RS03665	COG0261	This protein binds to 23S rRNA in the presence of protein L20
AWC33_RS03670	COG2868	ribosomal protein
AWC33_RS03675	COG0211	Belongs to the bacterial ribosomal protein bL27 family
AWC33_RS03680	COG0006	proline dipeptidase activity
AWC33_RS03685	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
AWC33_RS03690	COG1302	Protein conserved in bacteria
AWC33_RS03710	COG1722	exodeoxyribonuclease VII activity
AWC33_RS03715	COG0142	geranyltranstransferase activity
AWC33_RS03720	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
AWC33_RS03725	COG1438	arginine binding
AWC33_RS03730	COG0497	DNA recombination
AWC33_RS03745	COG0194	GDP metabolic process
AWC33_RS03755	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
AWC33_RS03760	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
AWC33_RS03770	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
AWC33_RS03770	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AWC33_RS03780	COG0515	serine threonine protein kinase
AWC33_RS03780	COG2815	serine threonine protein kinase
AWC33_RS03785	COG1162	GTPase activity
AWC33_RS03790	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
AWC33_RS03795	COG1564	THIamine pyrophosphokinase
AWC33_RS03810	COG1461	Dihydroxyacetone kinase
AWC33_RS03815	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
AWC33_RS03825	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AWC33_RS03835	COG4608	Belongs to the ABC transporter superfamily
AWC33_RS03840	COG0601	transmembrane transport
AWC33_RS03845	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AWC33_RS03850	COG0747	negative chemotaxis
AWC33_RS03855	COG0571	ribonuclease III activity
AWC33_RS03860	COG1196	nuclear chromosome segregation
AWC33_RS03865	COG0552	protein localization to endoplasmic reticulum
AWC33_RS03880	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
AWC33_RS03890	COG1837	Belongs to the UPF0109 family
AWC33_RS03915	COG4224	UPF0291 protein
AWC33_RS03920	COG3763	UPF0154 protein
AWC33_RS03925	COG1132	(ABC) transporter
AWC33_RS03930	COG1132	(ABC) transporter
AWC33_RS03940	COG0531	amino acid
AWC33_RS03945	COG0204	Acyl-transferase
AWC33_RS03950	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
AWC33_RS03980	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
AWC33_RS03985	COG4589	Belongs to the CDS family
AWC33_RS03990	COG0750	zinc metalloprotease
AWC33_RS04010	COG0195	Participates in both transcription termination and antitermination
AWC33_RS04015	COG2740	Nucleic-acid-binding protein implicated in transcription termination
AWC33_RS04035	COG0861	Integral membrane protein TerC family
AWC33_RS04045	COG0196	riboflavin kinase activity
AWC33_RS04050	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AWC33_RS04060	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
AWC33_RS04080	COG2801	Transposase and inactivated derivatives
AWC33_RS04105	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
AWC33_RS04105	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
AWC33_RS04115	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
AWC33_RS04135	COG2249	NAD(P)H dehydrogenase (quinone) activity
AWC33_RS04175	COG2094	Belongs to the DNA glycosylase MPG family
AWC33_RS04190	COG1385	rRNA (uridine-N3-)-methyltransferase activity
AWC33_RS04200	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AWC33_RS04215	COG0860	N-Acetylmuramoyl-L-alanine amidase
AWC33_RS04215	COG4991	sh3 domain protein
AWC33_RS04215	COG3103	Sh3 type 3 domain protein
AWC33_RS04225	COG1131	(ABC) transporter
AWC33_RS04250	COG2130	NADP-dependent
AWC33_RS04270	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AWC33_RS04275	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AWC33_RS04280	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
AWC33_RS04295	COG1610	YqeY-like protein
AWC33_RS04300	COG1702	phosphate starvation-inducible protein PhoH
AWC33_RS04315	COG0295	cytidine deaminase activity
AWC33_RS04325	COG1381	Involved in DNA repair and RecF pathway recombination
AWC33_RS04350	COG0358	DNA primase activity
AWC33_RS04355	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AWC33_RS04360	COG2384	SAM-dependent methyltransferase
AWC33_RS04365	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
AWC33_RS04370	COG1942	4-Oxalocrotonate Tautomerase
AWC33_RS04375	COG2151	metal-sulfur cluster biosynthetic enzyme
AWC33_RS04390	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
AWC33_RS04390	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
AWC33_RS04420	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AWC33_RS04420	COG1199	ATP-dependent helicase activity
AWC33_RS04430	COG0436	Aminotransferase
AWC33_RS04445	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
AWC33_RS04450	COG2131	deaminase
AWC33_RS04455	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AWC33_RS04485	COG0116	Belongs to the methyltransferase superfamily
AWC33_RS04500	COG0095	Lipoate-protein ligase
AWC33_RS04505	COG3590	peptidase
AWC33_RS04510	COG0583	DNA-binding transcription factor activity
AWC33_RS04515	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AWC33_RS04520	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AWC33_RS04525	COG1393	Belongs to the ArsC family
AWC33_RS04540	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AWC33_RS04550	COG0328	RNA-DNA hybrid ribonuclease activity
AWC33_RS04565	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
AWC33_RS04570	COG0564	pseudouridine synthase activity
AWC33_RS04575	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
AWC33_RS04580	COG2233	PERMEase
AWC33_RS04590	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
AWC33_RS04595	COG0505	Belongs to the CarA family
AWC33_RS04610	COG0284	orotidine-5'-phosphate decarboxylase activity
AWC33_RS04615	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
AWC33_RS04620	COG0280	phosphate acetyltransferase
AWC33_RS04625	COG3426	butyrate kinase activity
AWC33_RS04630	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AWC33_RS04635	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
AWC33_RS04640	COG0022	dehydrogenase e1 component
AWC33_RS04645	COG0508	dehydrogenase complex catalyzes the overall conversion of
AWC33_RS04650	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
AWC33_RS04665	COG1293	RNA-binding protein homologous to eukaryotic snRNP
AWC33_RS04670	COG1307	EDD domain protein, DegV family
AWC33_RS04675	COG0494	nUDIX hydrolase
AWC33_RS04680	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AWC33_RS04695	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
AWC33_RS04730	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AWC33_RS04735	COG0778	Nitroreductase
AWC33_RS04755	COG0745	RESPONSE REGULATOR receiver
AWC33_RS04760	COG5002	protein histidine kinase activity
AWC33_RS04765	COG1136	(ABC) transporter
AWC33_RS04770	COG0577	efflux transmembrane transporter activity
AWC33_RS04780	COG4974	Belongs to the 'phage' integrase family
AWC33_RS04785	COG1227	inorganic diphosphatase activity
AWC33_RS04790	COG0583	DNA-binding transcription factor activity
AWC33_RS04795	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
AWC33_RS04800	COG1882	Formate acetyltransferase
AWC33_RS04805	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
AWC33_RS04810	COG0187	DNA topoisomerase II activity
AWC33_RS04825	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
AWC33_RS04845	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AWC33_RS04850	COG0758	DNA mediated transformation
AWC33_RS04870	COG3409	Peptidoglycan-binding domain 1 protein
AWC33_RS04870	COG0793	Belongs to the peptidase S41A family
AWC33_RS04880	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AWC33_RS04890	COG2755	lipolytic protein G-D-S-L family
AWC33_RS04895	COG1307	EDD domain protein, DegV family
AWC33_RS04900	COG1272	protein, Hemolysin III
AWC33_RS04915	COG0488	(ABC) transporter
AWC33_RS04930	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AWC33_RS04935	COG0457	Tetratricopeptide repeat
AWC33_RS04950	COG0539	negative regulation of cytoplasmic translation
AWC33_RS04965	COG0514	ATP-dependent DNA helicase (RecQ)
AWC33_RS04980	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
AWC33_RS04985	COG1187	pseudouridine synthase activity
AWC33_RS04990	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
AWC33_RS04995	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
AWC33_RS05000	COG0456	acetyltransferase
AWC33_RS05010	COG2996	Protein conserved in bacteria
AWC33_RS05030	COG0587	DNA-directed DNA polymerase activity
AWC33_RS05045	COG0737	Belongs to the 5'-nucleotidase family
AWC33_RS05060	COG0542	response to heat
AWC33_RS05070	COG0300	oxidoreductase activity
AWC33_RS05080	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
AWC33_RS05080	COG2755	lipolytic protein G-D-S-L family
AWC33_RS05090	COG1349	DNA-binding transcription factor activity
AWC33_RS05095	COG1105	Belongs to the carbohydrate kinase PfkB family
AWC33_RS05100	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AWC33_RS05100	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AWC33_RS05100	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AWC33_RS05110	COG1126	abc transporter atp-binding protein
AWC33_RS05115	COG0765	amino acid transport
AWC33_RS05135	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
AWC33_RS05145	COG1132	(ABC) transporter
AWC33_RS05180	COG1466	dna polymerase III delta subunit
AWC33_RS05185	COG0658	competence protein
AWC33_RS05185	COG2333	competence protein COMEC
AWC33_RS05195	COG3480	Lon protease (S16) C-terminal proteolytic domain
AWC33_RS05205	COG0742	ribosomal rna small subunit methyltransferase
AWC33_RS05210	COG4471	UPF0298 protein
AWC33_RS05215	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
AWC33_RS05220	COG0772	Belongs to the SEDS family
AWC33_RS05225	COG2826	transposase and inactivated derivatives, IS30 family
AWC33_RS05230	COG1217	gtp-binding protein TYPA
AWC33_RS05235	COG0483	inositol monophosphate 1-phosphatase activity
AWC33_RS05305	COG1597	lipid kinase activity
AWC33_RS05315	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
AWC33_RS05345	COG1104	cysteine desulfurase activity
AWC33_RS05360	COG0494	nUDIX hydrolase
AWC33_RS05370	COG3853	Toxic anion resistance protein (TelA)
AWC33_RS05375	COG2814	Major facilitator Superfamily
AWC33_RS05385	COG1278	Cold shock
AWC33_RS05395	COG3599	regulation of cell shape
AWC33_RS05415	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
AWC33_RS05445	COG0768	penicillin binding
AWC33_RS05460	COG2001	Belongs to the MraZ family
AWC33_RS05470	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AWC33_RS05475	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AWC33_RS05485	COG0765	amino acid transport
AWC33_RS05490	COG2894	cell division
AWC33_RS05495	COG0850	regulation of cytokinetic process
AWC33_RS05505	COG1792	Involved in formation and maintenance of cell shape
AWC33_RS05510	COG1077	Cell shape determining protein MreB Mrl
AWC33_RS05530	COG0525	valine-tRNA ligase activity
AWC33_RS05535	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
AWC33_RS05545	COG1104	cysteine desulfurase activity
AWC33_RS05550	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
AWC33_RS05555	COG1956	GAF domain-containing protein
AWC33_RS05585	COG2183	response to ionizing radiation
AWC33_RS05650	COG1131	(ABC) transporter
AWC33_RS05655	COG0842	Transport permease protein
AWC33_RS05660	COG4585	Histidine kinase
AWC33_RS05665	COG2197	response regulator
AWC33_RS05670	COG1307	EDD domain protein, DegV family
AWC33_RS05675	COG1178	ABC-type Fe3 transport system permease component
AWC33_RS05680	COG3842	ATPase activity
AWC33_RS05685	COG1840	ABC-type Fe3 transport system, periplasmic component
AWC33_RS05690	COG4753	response regulator
AWC33_RS05690	COG2207	Transcriptional regulator
AWC33_RS05695	COG2972	Histidine kinase
AWC33_RS05755	COG0745	RESPONSE REGULATOR receiver
AWC33_RS05760	COG2205	protein histidine kinase activity
AWC33_RS05765	COG4166	transmembrane transport
AWC33_RS05775	COG1428	Deoxynucleoside kinase
AWC33_RS05785	COG1028	Short-chain dehydrogenase reductase Sdr
AWC33_RS05800	COG1760	l-serine dehydratase
AWC33_RS05805	COG1760	l-serine dehydratase
AWC33_RS05815	COG5506	Protein of unknown function (DUF1694)
AWC33_RS05820	COG0189	ligase activity
AWC33_RS05820	COG2918	glutathione biosynthetic process
AWC33_RS05825	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
AWC33_RS05835	COG0589	response to stress
AWC33_RS05865	COG0719	Fe-S assembly protein
AWC33_RS05870	COG0822	iron-sulfur transferase activity
AWC33_RS05875	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AWC33_RS05880	COG0719	Fe-S assembly protein
AWC33_RS05890	COG2011	ABC-type metal ion transport system permease component
AWC33_RS05900	COG1464	Belongs to the NlpA lipoprotein family
AWC33_RS05905	COG1464	Belongs to the NlpA lipoprotein family
AWC33_RS05910	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AWC33_RS05920	COG0509	glycine decarboxylation via glycine cleavage system
AWC33_RS05925	COG0772	Belongs to the SEDS family
AWC33_RS05945	COG1077	Cell shape determining protein MreB Mrl
AWC33_RS05990	COG0356	it plays a direct role in the translocation of protons across the membrane
AWC33_RS06005	COG0009	L-threonylcarbamoyladenylate synthase
AWC33_RS06010	COG2890	protein-(glutamine-N5) methyltransferase activity
AWC33_RS06020	COG1435	thymidine kinase activity
AWC33_RS06025	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
AWC33_RS06035	COG2514	catechol 2,3-dioxygenase activity
AWC33_RS06085	COG3548	integral membrane protein
AWC33_RS06090	COG2814	Major facilitator Superfamily
AWC33_RS06115	COG0590	tRNA wobble adenosine to inosine editing
AWC33_RS06165	COG4975	Glucose uptake
AWC33_RS06175	COG1368	sulfuric ester hydrolase activity
AWC33_RS06195	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
AWC33_RS06200	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
AWC33_RS06215	COG1705	Flagellar rod assembly protein muramidase FlgJ
AWC33_RS06225	COG1278	Cold shock
AWC33_RS06230	COG4129	membrane
AWC33_RS06240	COG0463	Glycosyl transferase, family 2
AWC33_RS06250	COG4485	Bacterial membrane protein, YfhO
AWC33_RS06255	COG3711	transcriptional antiterminator
AWC33_RS06260	COG1263	PTS System
AWC33_RS06260	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AWC33_RS06260	COG2190	(PTS) system
AWC33_RS06280	COG0562	UDP-galactopyranose mutase
AWC33_RS06315	COG1210	Utp--glucose-1-phosphate uridylyltransferase
AWC33_RS06335	COG0463	Glycosyl transferase, family 2
AWC33_RS06340	COG0024	Methionine aminopeptidase
AWC33_RS06345	COG0716	FMN binding
AWC33_RS06350	COG1295	ribonuclease BN
AWC33_RS06365	COG2309	aminopeptidase activity
AWC33_RS06370	COG0514	ATP-dependent DNA helicase (RecQ)
AWC33_RS06390	COG1447	Phosphotransferase system cellobiose-specific component IIA
AWC33_RS06400	COG0673	inositol 2-dehydrogenase activity
AWC33_RS06440	COG2814	Major facilitator Superfamily
AWC33_RS06445	COG3590	peptidase
AWC33_RS06450	COG2326	polyphosphate kinase activity
AWC33_RS06455	COG0561	phosphatase activity
AWC33_RS06460	COG2814	Major facilitator Superfamily
AWC33_RS06465	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AWC33_RS06525	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AWC33_RS06550	COG4372	Transposase
AWC33_RS06570	COG3850	Histidine kinase
AWC33_RS06570	COG5002	protein histidine kinase activity
AWC33_RS06575	COG0745	RESPONSE REGULATOR receiver
AWC33_RS06610	COG1442	glycosyl transferase family 8
AWC33_RS06625	COG1113	amino acid transport
AWC33_RS06635	COG0827	DNA restriction-modification system
AWC33_RS06690	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
AWC33_RS06710	COG1131	(ABC) transporter
AWC33_RS06720	COG1309	transcriptional regulator
AWC33_RS06725	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
AWC33_RS06740	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
AWC33_RS06745	COG1177	transmembrane transport
AWC33_RS06750	COG1176	ABC-type spermidine putrescine transport system, permease component I
AWC33_RS06760	COG3800	Transcriptional regulator
AWC33_RS06760	COG1396	sequence-specific DNA binding
AWC33_RS06775	COG0708	Exodeoxyribonuclease III
AWC33_RS06785	COG1668	transmembrane transport
AWC33_RS06790	COG4152	abc transporter atp-binding protein
AWC33_RS06795	COG0802	atpase or kinase
AWC33_RS06800	COG0280	phosphate acetyltransferase
AWC33_RS06810	COG0561	phosphatase activity
AWC33_RS06830	COG1175	transmembrane transport
AWC33_RS06835	COG0395	ABC-type sugar transport system, permease component
AWC33_RS06860	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AWC33_RS06890	COG1609	Transcriptional regulator
AWC33_RS06905	COG0557	exoribonuclease II activity
AWC33_RS06915	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
AWC33_RS06955	COG2390	Transcriptional regulator
AWC33_RS06975	COG1846	Transcriptional regulator
AWC33_RS06985	COG0391	Required for morphogenesis under gluconeogenic growth conditions
AWC33_RS07000	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
AWC33_RS07020	COG1136	(ABC) transporter
AWC33_RS07025	COG2205	protein histidine kinase activity
AWC33_RS07035	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AWC33_RS07040	COG0492	ferredoxin-NADP+ reductase activity
AWC33_RS07050	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
AWC33_RS07060	COG1950	PFAM Membrane protein of
AWC33_RS07075	COG0704	Plays a role in the regulation of phosphate uptake
AWC33_RS07080	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
AWC33_RS07085	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
AWC33_RS07090	COG0581	inorganic phosphate transmembrane transporter activity
AWC33_RS07095	COG0573	inorganic phosphate transmembrane transporter activity
AWC33_RS07105	COG5002	protein histidine kinase activity
AWC33_RS07110	COG0745	RESPONSE REGULATOR receiver
AWC33_RS07120	COG2177	Part of the ABC transporter FtsEX involved in
AWC33_RS07125	COG2884	Cell division ATP-binding protein ftsE
AWC33_RS07150	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
AWC33_RS07155	COG1739	Uncharacterized protein family UPF0029
AWC33_RS07165	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
AWC33_RS07175	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
AWC33_RS07180	COG1426	Protein conserved in bacteria
AWC33_RS07185	COG1028	Short-chain dehydrogenase reductase Sdr
AWC33_RS07190	COG0612	Peptidase, M16
AWC33_RS07195	COG0612	Peptidase, M16
AWC33_RS07200	COG1674	ftsk spoiiie
AWC33_RS07210	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
AWC33_RS07215	COG2226	methyltransferase
AWC33_RS07230	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
AWC33_RS07240	COG2706	6-phosphogluconolactonase activity
AWC33_RS07245	COG2826	transposase and inactivated derivatives, IS30 family
AWC33_RS07255	COG3142	Participates in the control of copper homeostasis
AWC33_RS07265	COG0564	pseudouridine synthase activity
AWC33_RS07275	COG2357	RelA SpoT domain protein
AWC33_RS07305	COG3830	Belongs to the UPF0237 family
AWC33_RS07315	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
AWC33_RS07320	COG0386	Belongs to the glutathione peroxidase family
AWC33_RS07325	COG0438	transferase activity, transferring glycosyl groups
AWC33_RS07345	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
AWC33_RS07355	COG1187	pseudouridine synthase activity
AWC33_RS07360	COG2244	polysaccharide biosynthetic process
AWC33_RS07370	COG0671	phosphoesterase, PA-phosphatase related
AWC33_RS07380	COG2814	Major facilitator Superfamily
AWC33_RS07390	COG0477	Major facilitator Superfamily
AWC33_RS07575	COG0735	belongs to the Fur family
AWC33_RS07580	COG1368	sulfuric ester hydrolase activity
AWC33_RS07590	COG0436	Aminotransferase
AWC33_RS07605	COG0438	transferase activity, transferring glycosyl groups
AWC33_RS07610	COG0438	transferase activity, transferring glycosyl groups
AWC33_RS07615	COG0531	amino acid
AWC33_RS07635	COG4372	Transposase
AWC33_RS07780	COG1098	S1 RNA binding domain
AWC33_RS07795	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
AWC33_RS07800	COG0586	Pfam SNARE associated Golgi protein
AWC33_RS07810	COG0647	UMP catabolic process
AWC33_RS07815	COG4470	Protein conserved in bacteria
AWC33_RS07820	COG0737	Belongs to the 5'-nucleotidase family
AWC33_RS07860	COG1011	Hydrolase
AWC33_RS07865	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AWC33_RS07870	COG1609	Transcriptional regulator
AWC33_RS07875	COG0006	proline dipeptidase activity
AWC33_RS07880	COG1827	regulation of RNA biosynthetic process
AWC33_RS07895	COG0668	transmembrane transport
AWC33_RS07910	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
AWC33_RS07920	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
AWC33_RS07925	COG1719	4-vinyl reductase, 4VR
AWC33_RS07930	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
AWC33_RS07940	COG1696	Membrane protein involved in D-alanine export
AWC33_RS07955	COG3118	belongs to the thioredoxin family
AWC33_RS08005	COG0513	Belongs to the DEAD box helicase family
AWC33_RS08010	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
AWC33_RS08015	COG4109	DRTGG domain
AWC33_RS08020	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AWC33_RS08025	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
AWC33_RS08035	COG1012	belongs to the aldehyde dehydrogenase family
AWC33_RS08035	COG1454	alcohol dehydrogenase
AWC33_RS08040	COG1862	Preprotein translocase
AWC33_RS08045	COG0343	queuine tRNA-ribosyltransferase activity
AWC33_RS08050	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
AWC33_RS08075	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
AWC33_RS08115	COG2267	carboxylic ester hydrolase activity
AWC33_RS08145	COG2267	carboxylic ester hydrolase activity
AWC33_RS08150	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
AWC33_RS08155	COG0105	UTP biosynthetic process
AWC33_RS08160	COG0300	oxidoreductase activity
AWC33_RS08180	COG1132	(ABC) transporter
AWC33_RS08195	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
AWC33_RS08220	COG3189	MarR family transcriptional regulator
AWC33_RS08225	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
AWC33_RS08240	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AWC33_RS08265	COG0628	permease
AWC33_RS08280	COG0604	alcohol dehydrogenase
AWC33_RS08370	COG0778	Nitroreductase
AWC33_RS08380	COG1028	Short-chain dehydrogenase reductase Sdr
AWC33_RS08395	COG5002	protein histidine kinase activity
AWC33_RS08400	COG0745	RESPONSE REGULATOR receiver
AWC33_RS08410	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
AWC33_RS08415	COG0463	Glycosyl transferase, family 2
AWC33_RS08425	COG0604	alcohol dehydrogenase
AWC33_RS08435	COG4120	Belongs to the binding-protein-dependent transport system permease family
AWC33_RS08450	COG1472	Belongs to the glycosyl hydrolase 3 family
AWC33_RS08460	COG2910	NAD(P)H-binding
AWC33_RS08475	COG0351	phosphomethylpyrimidine kinase
AWC33_RS08495	COG2249	NAD(P)H dehydrogenase (quinone) activity
AWC33_RS08505	COG1194	a g-specific adenine glycosylase
AWC33_RS08525	COG0419	ATPase involved in DNA repair
AWC33_RS08540	COG1349	DNA-binding transcription factor activity
AWC33_RS08555	COG3684	Belongs to the aldolase LacD family
AWC33_RS08575	COG3775	system Galactitol-specific IIC component
AWC33_RS08600	COG2017	converts alpha-aldose to the beta-anomer
AWC33_RS08605	COG1609	Transcriptional regulator
AWC33_RS08610	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
AWC33_RS08615	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AWC33_RS08625	COG1447	Phosphotransferase system cellobiose-specific component IIA
AWC33_RS08635	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AWC33_RS08635	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AWC33_RS08640	COG3711	transcriptional antiterminator
AWC33_RS08645	COG1215	transferase activity, transferring glycosyl groups
AWC33_RS08650	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
AWC33_RS08655	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
AWC33_RS08660	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
AWC33_RS08665	COG1573	uracil-dna glycosylase
AWC33_RS08675	COG0488	(ABC) transporter
AWC33_RS08685	COG1285	pathogenesis
AWC33_RS08695	COG0004	ammonium transporteR
AWC33_RS08700	COG0604	alcohol dehydrogenase
AWC33_RS08720	COG1131	(ABC) transporter
AWC33_RS08740	COG0025	NhaP-type Na H and K H
AWC33_RS08750	COG1113	amino acid transport
AWC33_RS08755	COG0656	L-ascorbic acid biosynthetic process
AWC33_RS08760	COG0702	epimerase
AWC33_RS08765	COG0488	(ABC) transporter
AWC33_RS08780	COG1278	Cold shock
AWC33_RS08785	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
AWC33_RS08790	COG0039	L-malate dehydrogenase activity
AWC33_RS08795	COG0531	amino acid
AWC33_RS08805	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AWC33_RS08805	COG1263	PTS System
AWC33_RS08805	COG2190	(PTS) system
AWC33_RS08810	COG0366	Alpha amylase catalytic
AWC33_RS08815	COG2188	Transcriptional regulator
AWC33_RS08820	COG2223	nitrite transmembrane transporter activity
AWC33_RS08825	COG1132	(ABC) transporter
AWC33_RS08830	COG1132	(ABC) transporter
AWC33_RS08835	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
AWC33_RS08840	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
AWC33_RS08860	COG1131	(ABC) transporter
AWC33_RS08870	COG0697	spore germination
AWC33_RS08940	COG1114	Component of the transport system for branched-chain amino acids
AWC33_RS08950	COG0765	amino acid transport
AWC33_RS08955	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AWC33_RS08960	COG0626	cystathionine gamma-synthase activity
AWC33_RS09010	COG2801	Transposase and inactivated derivatives
AWC33_RS09045	COG2826	transposase and inactivated derivatives, IS30 family
AWC33_RS09060	COG2801	Transposase and inactivated derivatives
AWC33_RS09165	COG1396	sequence-specific DNA binding
AWC33_RS09215	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AWC33_RS09220	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
AWC33_RS09225	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
AWC33_RS09230	COG2271	Major facilitator Superfamily
AWC33_RS09240	COG1028	Short-chain dehydrogenase reductase Sdr
AWC33_RS09260	COG0531	amino acid
AWC33_RS09265	COG0308	aminopeptidase N
AWC33_RS09300	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AWC33_RS09355	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
AWC33_RS09370	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AWC33_RS09375	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AWC33_RS09385	COG2723	6-phospho-beta-galactosidase activity
AWC33_RS09395	COG1733	regulation of RNA biosynthetic process
AWC33_RS09405	COG0656	L-ascorbic acid biosynthetic process
AWC33_RS09410	COG0789	Transcriptional regulator
AWC33_RS09425	COG0174	glutamine synthetase
AWC33_RS09430	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
AWC33_RS09435	COG2226	methyltransferase
AWC33_RS09450	COG0028	Belongs to the TPP enzyme family
AWC33_RS09470	COG2814	Major facilitator Superfamily
AWC33_RS09515	COG2376	Dihydroxyacetone kinase
AWC33_RS09520	COG1461	Dihydroxyacetone kinase
AWC33_RS09525	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
AWC33_RS09555	COG1464	Belongs to the NlpA lipoprotein family
AWC33_RS09590	COG1132	(ABC) transporter
AWC33_RS09595	COG1132	(ABC) transporter
AWC33_RS09600	COG0366	Alpha amylase catalytic
AWC33_RS09615	COG3716	PTS system mannose fructose sorbose family IID component
AWC33_RS09625	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AWC33_RS09630	COG1609	Transcriptional regulator
AWC33_RS09640	COG0561	phosphatase activity
AWC33_RS09645	COG0446	pyridine nucleotide-disulphide oxidoreductase
AWC33_RS09695	COG0765	amino acid transport
AWC33_RS09700	COG0765	amino acid transport
AWC33_RS09705	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AWC33_RS09710	COG1126	abc transporter atp-binding protein
AWC33_RS09730	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
AWC33_RS09735	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
AWC33_RS09740	COG1349	DNA-binding transcription factor activity
AWC33_RS09745	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AWC33_RS09765	COG1053	succinate dehydrogenase
AWC33_RS09795	COG2814	Major facilitator Superfamily
AWC33_RS09815	COG1879	ABC-type sugar transport system periplasmic component
AWC33_RS09820	COG1172	Belongs to the binding-protein-dependent transport system permease family
AWC33_RS09835	COG1609	Transcriptional regulator
AWC33_RS09860	COG0351	phosphomethylpyrimidine kinase
AWC33_RS09880	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
AWC33_RS09890	COG1129	ABC transporter
AWC33_RS09905	COG4166	transmembrane transport
AWC33_RS09910	COG2195	Cleaves the N-terminal amino acid of tripeptides
AWC33_RS09920	COG1363	Peptidase, m42
AWC33_RS09925	COG1447	Phosphotransferase system cellobiose-specific component IIA
AWC33_RS09930	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AWC33_RS09945	COG2801	Transposase and inactivated derivatives
AWC33_RS09955	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
AWC33_RS09960	COG2222	sugar isomerase
AWC33_RS09965	COG2188	Transcriptional regulator
AWC33_RS09970	COG1482	cell wall glycoprotein biosynthetic process
AWC33_RS09985	COG2182	Extracellular solute-binding protein
AWC33_RS10005	COG0446	pyridine nucleotide-disulphide oxidoreductase
AWC33_RS10035	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
AWC33_RS10040	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
AWC33_RS10050	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AWC33_RS10080	COG0683	leucine binding
AWC33_RS10095	COG3118	belongs to the thioredoxin family
AWC33_RS10120	COG0488	(ABC) transporter
AWC33_RS10145	COG1216	Glycosyl transferase, family 2
AWC33_RS10160	COG1114	Component of the transport system for branched-chain amino acids
AWC33_RS10165	COG1316	TRANSCRIPTIONal
AWC33_RS10170	COG1164	Oligoendopeptidase f
AWC33_RS10175	COG2084	Dehydrogenase
AWC33_RS10190	COG1121	(ABC) transporter
AWC33_RS10200	COG2826	transposase and inactivated derivatives, IS30 family
AWC33_RS10205	COG2610	gluconate transmembrane transporter activity
AWC33_RS10215	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
AWC33_RS10220	COG1737	Transcriptional regulator
AWC33_RS10225	COG0656	L-ascorbic acid biosynthetic process
AWC33_RS10230	COG1794	racemase activity, acting on amino acids and derivatives
AWC33_RS10245	COG1686	Belongs to the peptidase S11 family
AWC33_RS10265	COG0516	GMP reductase activity
AWC33_RS10265	COG0517	IMP dehydrogenase activity
AWC33_RS10275	COG0012	GTP binding
AWC33_RS10280	COG4481	Protein conserved in bacteria
AWC33_RS10285	COG1475	DNA binding
AWC33_RS10290	COG1192	Involved in chromosome partitioning
AWC33_RS10310	COG3442	glutamine amidotransferase
AWC33_RS10340	COG1302	Protein conserved in bacteria
AWC33_RS10355	COG2261	transglycosylase associated protein
AWC33_RS10365	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AWC33_RS10380	COG0716	FMN binding
AWC33_RS10420	COG0446	pyridine nucleotide-disulphide oxidoreductase
AWC33_RS10430	COG1396	sequence-specific DNA binding
AWC33_RS10435	COG1132	(ABC) transporter
AWC33_RS10455	COG1131	(ABC) transporter
AWC33_RS10475	COG4166	transmembrane transport
AWC33_RS10480	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
AWC33_RS10495	COG1131	(ABC) transporter
AWC33_RS10510	COG0477	Major facilitator Superfamily
AWC33_RS10535	COG3328	transposase activity
AWC33_RS10540	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
AWC33_RS10565	COG1511	domain protein
AWC33_RS10605	COG3414	Phosphotransferase system galactitol-specific IIB component
AWC33_RS10610	COG3775	system Galactitol-specific IIC component
AWC33_RS10650	COG1511	domain protein
AWC33_RS10675	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
AWC33_RS10735	COG0346	lactoylglutathione lyase activity
AWC33_RS10745	COG2252	PERMEase
AWC33_RS10780	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AWC33_RS10885	COG1328	CTP reductase activity
AWC33_RS10895	COG1131	(ABC) transporter
AWC33_RS10905	COG3620	sequence-specific DNA binding
AWC33_RS10910	COG0583	DNA-binding transcription factor activity
AWC33_RS10915	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
AWC33_RS10920	COG0640	Transcriptional regulator
AWC33_RS10925	COG2217	Heavy metal translocating P-type atpase
AWC33_RS10950	COG1136	(ABC) transporter
AWC33_RS10950	COG0577	efflux transmembrane transporter activity
AWC33_RS10955	COG1309	transcriptional regulator
AWC33_RS10960	COG1737	Transcriptional regulator
AWC33_RS10965	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
AWC33_RS10980	COG0305	Participates in initiation and elongation during chromosome replication
AWC33_RS11025	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
AWC33_RS11030	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
AWC33_RS11035	COG0527	aspartate kinase activity
AWC33_RS11040	COG0019	diaminopimelate decarboxylase activity
AWC33_RS11060	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
AWC33_RS11090	COG1131	(ABC) transporter
AWC33_RS11155	COG2826	transposase and inactivated derivatives, IS30 family
AWC33_RS11170	COG4372	Transposase
AWC33_RS11185	COG0366	Alpha amylase catalytic
AWC33_RS11195	COG1609	Transcriptional regulator
AWC33_RS11210	COG2801	Transposase and inactivated derivatives
AWC33_RS11235	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
AWC33_RS11250	COG2801	Transposase and inactivated derivatives
AWC33_RS11270	COG1609	Transcriptional regulator
AWC33_RS11275	COG0366	Alpha amylase catalytic
AWC33_RS11295	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AWC33_RS11305	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AWC33_RS11310	COG2801	Transposase and inactivated derivatives
AWC33_RS11335	COG3711	transcriptional antiterminator
AWC33_RS11340	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AWC33_RS11340	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AWC33_RS11350	COG1447	Phosphotransferase system cellobiose-specific component IIA
AWC33_RS11375	COG0159	tryptophan synthase activity
AWC33_RS11380	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AWC33_RS11390	COG2217	Heavy metal translocating P-type atpase
AWC33_RS11430	COG1732	Glycine betaine
AWC33_RS11445	COG1309	transcriptional regulator
AWC33_RS11460	COG2814	Major facilitator Superfamily
AWC33_RS11465	COG1132	(ABC) transporter
AWC33_RS11485	COG2801	Transposase and inactivated derivatives
AWC33_RS11550	COG0561	phosphatase activity
AWC33_RS11610	COG1294	oxidase, subunit
AWC33_RS11615	COG1271	oxidase subunit
AWC33_RS11630	COG0629	single-stranded DNA binding
AWC33_RS11645	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
AWC33_RS11655	COG0187	DNA topoisomerase II activity
AWC33_RS11665	COG2501	S4 domain
AWC33_RS11670	COG0592	DNA-directed DNA polymerase activity
AWC33_RS11690	COG0706	membrane insertase activity
AWC33_RS11730	COG1473	amidohydrolase
AWC33_RS11735	COG0371	Dehydrogenase
AWC33_RS11750	COG0577	efflux transmembrane transporter activity
AWC33_RS11755	COG1136	(ABC) transporter
AWC33_RS11755	COG0577	efflux transmembrane transporter activity
AWC33_RS11775	COG0561	phosphatase activity
AWC33_RS11785	COG2213	PTS system mannitol-specific
AWC33_RS11795	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
AWC33_RS11815	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
AWC33_RS11825	COG2261	transglycosylase associated protein
AWC33_RS11855	COG3290	protein histidine kinase activity
AWC33_RS11860	COG3493	citrate carrier protein
AWC33_RS11885	COG0561	phosphatase activity
AWC33_RS11890	COG0110	maltose O-acetyltransferase activity
AWC33_RS11895	COG0438	transferase activity, transferring glycosyl groups
AWC33_RS11900	COG1305	Transglutaminase-like
AWC33_RS11910	COG0714	Associated with various cellular activities
AWC33_RS11925	COG0765	amino acid transport
AWC33_RS11930	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AWC33_RS11940	COG3001	Fructosamine kinase
AWC33_RS11985	COG1126	abc transporter atp-binding protein
AWC33_RS11990	COG0765	amino acid transport
AWC33_RS12025	COG3715	PTS system
AWC33_RS12030	COG3716	PTS system mannose fructose sorbose family IID component
AWC33_RS12040	COG0667	Aldo Keto reductase
AWC33_RS12045	COG2807	transmembrane transport
AWC33_RS12050	COG2814	Major facilitator Superfamily
AWC33_RS12055	COG1335	isochorismatase
AWC33_RS12075	COG1447	Phosphotransferase system cellobiose-specific component IIA
AWC33_RS12080	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AWC33_RS12085	COG2188	Transcriptional regulator
AWC33_RS12090	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AWC33_RS12120	COG0765	amino acid transport
AWC33_RS12125	COG2267	carboxylic ester hydrolase activity
AWC33_RS12130	COG0745	RESPONSE REGULATOR receiver
AWC33_RS12135	COG5002	protein histidine kinase activity
AWC33_RS12150	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
AWC33_RS12160	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AWC33_RS12175	COG2217	Heavy metal translocating P-type atpase
AWC33_RS12210	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
AWC33_RS12235	COG2365	Tyrosine phosphatase family
AWC33_RS12275	COG2076	Multidrug Resistance protein
AWC33_RS12285	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
AWC33_RS12300	COG3716	PTS system mannose fructose sorbose family IID component
AWC33_RS12305	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AWC33_RS12310	COG1737	Transcriptional regulator
AWC33_RS12315	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
AWC33_RS12325	COG4948	Mandelate Racemase Muconate Lactonizing
AWC33_RS12345	COG1335	isochorismatase
AWC33_RS12350	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
AWC33_RS12355	COG3842	ATPase activity
AWC33_RS12365	COG0395	ABC-type sugar transport system, permease component
AWC33_RS12375	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AWC33_RS12410	COG0456	acetyltransferase
AWC33_RS12420	COG2801	Transposase and inactivated derivatives
AWC33_RS12440	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AWC33_RS12455	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
AWC33_RS12460	COG1349	DNA-binding transcription factor activity
AWC33_RS12465	COG3623	hexulose-6-phosphate isomerase
AWC33_RS12470	COG0561	phosphatase activity
AWC33_RS12495	COG3730	PTS system glucitol sorbitol-specific
AWC33_RS12500	COG3732	PTS system glucitol sorbitol-specific
AWC33_RS12540	COG2801	Transposase and inactivated derivatives
AWC33_RS12585	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AWC33_RS12585	COG1263	PTS System
AWC33_RS12605	COG0745	RESPONSE REGULATOR receiver
AWC33_RS12610	COG5002	protein histidine kinase activity
AWC33_RS12615	COG0586	Pfam SNARE associated Golgi protein
AWC33_RS12625	COG0463	Glycosyl transferase, family 2
AWC33_RS12655	COG1028	Short-chain dehydrogenase reductase Sdr
AWC33_RS12665	COG1414	Transcriptional regulator
AWC33_RS12675	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
AWC33_RS12680	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AWC33_RS12685	COG3715	PTS system
AWC33_RS12735	COG1349	DNA-binding transcription factor activity
AWC33_RS12750	COG3775	system Galactitol-specific IIC component
AWC33_RS12765	COG2188	Transcriptional regulator
AWC33_RS12770	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AWC33_RS12795	COG1940	carbohydrate kinase activity
AWC33_RS12800	COG2723	6-phospho-beta-galactosidase activity
AWC33_RS12810	COG1447	Phosphotransferase system cellobiose-specific component IIA
AWC33_RS12820	COG0800	Aldolase
AWC33_RS12825	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AWC33_RS12830	COG3414	Phosphotransferase system galactitol-specific IIB component
AWC33_RS12835	COG3775	system Galactitol-specific IIC component
AWC33_RS12840	COG4948	Mandelate Racemase Muconate Lactonizing
AWC33_RS12865	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
AWC33_RS12875	COG1105	Belongs to the carbohydrate kinase PfkB family
AWC33_RS12880	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AWC33_RS12880	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AWC33_RS12880	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AWC33_RS12890	COG1811	Na channel or pump
AWC33_RS12895	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
AWC33_RS12900	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AWC33_RS12915	COG0561	phosphatase activity
AWC33_RS12920	COG0588	phosphoglycerate mutase activity
AWC33_RS12945	COG0561	phosphatase activity
AWC33_RS12950	COG0667	Aldo Keto reductase
AWC33_RS12955	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
AWC33_RS12965	COG1418	mRNA catabolic process
AWC33_RS12990	COG3973	AAA domain
AWC33_RS12995	COG1174	glycine betaine transport
AWC33_RS13005	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AWC33_RS13015	COG1704	LemA family
AWC33_RS13020	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
AWC33_RS13025	COG0534	Mate efflux family protein
AWC33_RS13035	COG2226	methyltransferase
AWC33_RS13040	COG4989	oxidoreductase activity
AWC33_RS13055	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
AWC33_RS13060	COG0248	Ppx GppA phosphatase
AWC33_RS13065	COG4086	secreted protein
AWC33_RS13075	COG1881	PFAM PEBP family protein
AWC33_RS13090	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
AWC33_RS13110	COG1801	Protein of unknown function DUF72
AWC33_RS13120	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AWC33_RS13120	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AWC33_RS13130	COG1132	(ABC) transporter
AWC33_RS13135	COG3290	protein histidine kinase activity
AWC33_RS13150	COG3684	Belongs to the aldolase LacD family
AWC33_RS13160	COG0084	hydrolase, TatD family'
AWC33_RS13165	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
AWC33_RS13170	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
AWC33_RS13175	COG4466	Protein conserved in bacteria
AWC33_RS13180	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
AWC33_RS13190	COG0390	transport system, permease component
AWC33_RS13195	COG4619	ABC transporter
AWC33_RS13200	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
AWC33_RS13210	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
AWC33_RS13215	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
AWC33_RS13245	COG1078	dGTPase activity
AWC33_RS13250	COG0095	Lipoate-protein ligase
AWC33_RS13270	COG0504	CTP synthase activity
AWC33_RS13275	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
AWC33_RS13305	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
AWC33_RS13335	COG2337	Toxic component of a toxin-antitoxin (TA) module
AWC33_RS13340	COG4708	membrane
AWC33_RS13345	COG0070	glutamate synthase
AWC33_RS13345	COG0069	glutamate synthase activity
AWC33_RS13345	COG0067	glutamate synthase
AWC33_RS13350	COG0493	'glutamate synthase
AWC33_RS13355	COG1376	ErfK ybiS ycfS ynhG family protein
AWC33_RS13370	COG0039	L-malate dehydrogenase activity
AWC33_RS13380	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
AWC33_RS13385	COG2244	polysaccharide biosynthetic process
AWC33_RS13390	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
AWC33_RS13400	COG1098	S1 RNA binding domain
AWC33_RS13405	COG0037	tRNA processing
AWC33_RS13410	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
AWC33_RS13455	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AWC33_RS13460	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
AWC33_RS13530	COG4463	regulation of RNA biosynthetic process
AWC33_RS13535	COG0542	response to heat
AWC33_RS13585	COG0450	alkyl hydroperoxide reductase
AWC33_RS13690	COG0200	Binds to the 23S rRNA
AWC33_RS13755	COG0789	Transcriptional regulator
AWC33_RS13765	COG1136	(ABC) transporter
AWC33_RS13790	COG2826	transposase and inactivated derivatives, IS30 family
AWC33_RS13825	COG4555	ABC transporter
AWC33_RS13840	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AWC33_RS13845	COG1116	anion transmembrane transporter activity
AWC33_RS13875	COG3639	organic phosphonate transmembrane transporter activity
AWC33_RS13895	COG0148	phosphopyruvate hydratase activity
AWC33_RS13905	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
AWC33_RS13995	COG1012	belongs to the aldehyde dehydrogenase family
AWC33_RS14000	COG1121	(ABC) transporter
AWC33_RS14005	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AWC33_RS14035	COG2814	Major facilitator Superfamily
AWC33_RS14045	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
AWC33_RS14050	COG1914	H( )-stimulated, divalent metal cation uptake system
AWC33_RS14065	COG0114	fumarate hydratase activity
AWC33_RS14070	COG1902	pentaerythritol trinitrate reductase activity
AWC33_RS14075	COG4221	oxidoreductase activity
AWC33_RS14080	COG4989	oxidoreductase activity
AWC33_RS14095	COG0110	maltose O-acetyltransferase activity
AWC33_RS14180	COG2274	protein secretion by the type I secretion system
AWC33_RS14185	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AWC33_RS14230	COG1695	Transcriptional regulator
AWC33_RS14270	COG3764	Sortase (surface protein transpeptidase)
AWC33_RS14295	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
AWC33_RS14330	COG1304	FMN binding
AWC33_RS14585	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit