locus-tag	class	description
FO269_RS00010	COG1956	GAF domain-containing protein
FO269_RS00040	COG3620	sequence-specific DNA binding
FO269_RS00045	COG2183	response to ionizing radiation
FO269_RS00085	COG0789	Transcriptional regulator
FO269_RS00095	COG1131	(ABC) transporter
FO269_RS00105	COG4585	Histidine kinase
FO269_RS00110	COG2197	response regulator
FO269_RS00115	COG1307	EDD domain protein, DegV family
FO269_RS00130	COG0454	-acetyltransferase
FO269_RS00165	COG0583	DNA-binding transcription factor activity
FO269_RS00185	COG0745	RESPONSE REGULATOR receiver
FO269_RS00190	COG2205	protein histidine kinase activity
FO269_RS00195	COG4166	transmembrane transport
FO269_RS00210	COG1428	Deoxynucleoside kinase
FO269_RS00220	COG1028	Short-chain dehydrogenase reductase Sdr
FO269_RS00235	COG1760	l-serine dehydratase
FO269_RS00240	COG1760	l-serine dehydratase
FO269_RS00250	COG5506	Protein of unknown function (DUF1694)
FO269_RS00255	COG0189	ligase activity
FO269_RS00255	COG2918	glutathione biosynthetic process
FO269_RS00260	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
FO269_RS00280	COG0589	response to stress
FO269_RS00310	COG0719	Fe-S assembly protein
FO269_RS00315	COG0822	iron-sulfur transferase activity
FO269_RS00320	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
FO269_RS00325	COG0719	Fe-S assembly protein
FO269_RS00335	COG2011	ABC-type metal ion transport system permease component
FO269_RS00355	COG1464	Belongs to the NlpA lipoprotein family
FO269_RS00360	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FO269_RS00365	COG0509	glycine decarboxylation via glycine cleavage system
FO269_RS00370	COG0772	Belongs to the SEDS family
FO269_RS00395	COG1077	Cell shape determining protein MreB Mrl
FO269_RS00440	COG0356	it plays a direct role in the translocation of protons across the membrane
FO269_RS00455	COG0009	L-threonylcarbamoyladenylate synthase
FO269_RS00460	COG2890	protein-(glutamine-N5) methyltransferase activity
FO269_RS00470	COG1435	thymidine kinase activity
FO269_RS00475	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
FO269_RS00490	COG2514	catechol 2,3-dioxygenase activity
FO269_RS00540	COG3548	integral membrane protein
FO269_RS00545	COG2814	Major facilitator Superfamily
FO269_RS00565	COG0590	tRNA wobble adenosine to inosine editing
FO269_RS00610	COG4975	Glucose uptake
FO269_RS00620	COG1368	sulfuric ester hydrolase activity
FO269_RS00635	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
FO269_RS00640	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
FO269_RS00655	COG1705	Flagellar rod assembly protein muramidase FlgJ
FO269_RS00665	COG1278	Cold shock
FO269_RS00685	COG4129	membrane
FO269_RS00695	COG0463	Glycosyl transferase, family 2
FO269_RS00705	COG4485	Bacterial membrane protein, YfhO
FO269_RS00715	COG3711	transcriptional antiterminator
FO269_RS00720	COG2190	(PTS) system
FO269_RS00720	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FO269_RS00720	COG1263	PTS System
FO269_RS00765	COG1210	Utp--glucose-1-phosphate uridylyltransferase
FO269_RS00785	COG0463	Glycosyl transferase, family 2
FO269_RS00795	COG0024	Methionine aminopeptidase
FO269_RS00800	COG0716	FMN binding
FO269_RS00805	COG1295	ribonuclease BN
FO269_RS00830	COG2309	aminopeptidase activity
FO269_RS00835	COG0514	ATP-dependent DNA helicase (RecQ)
FO269_RS00855	COG1447	Phosphotransferase system cellobiose-specific component IIA
FO269_RS00865	COG0673	inositol 2-dehydrogenase activity
FO269_RS00905	COG2814	Major facilitator Superfamily
FO269_RS00910	COG3590	peptidase
FO269_RS00915	COG2326	polyphosphate kinase activity
FO269_RS00920	COG0561	phosphatase activity
FO269_RS00925	COG2814	Major facilitator Superfamily
FO269_RS00930	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FO269_RS00990	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FO269_RS01025	COG3850	Histidine kinase
FO269_RS01025	COG5002	protein histidine kinase activity
FO269_RS01030	COG0745	RESPONSE REGULATOR receiver
FO269_RS01050	COG2261	transglycosylase associated protein
FO269_RS01075	COG4695	Portal protein
FO269_RS01190	COG1113	amino acid transport
FO269_RS01200	COG0827	DNA restriction-modification system
FO269_RS01230	COG1459	type II secretion system
FO269_RS01235	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FO269_RS01255	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FO269_RS01285	COG1309	transcriptional regulator
FO269_RS01290	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
FO269_RS01305	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
FO269_RS01310	COG1177	transmembrane transport
FO269_RS01315	COG1176	ABC-type spermidine putrescine transport system, permease component I
FO269_RS01325	COG3800	Transcriptional regulator
FO269_RS01325	COG1396	sequence-specific DNA binding
FO269_RS01340	COG0708	Exodeoxyribonuclease III
FO269_RS01350	COG1668	transmembrane transport
FO269_RS01355	COG4152	abc transporter atp-binding protein
FO269_RS01365	COG0802	atpase or kinase
FO269_RS01370	COG0280	phosphate acetyltransferase
FO269_RS01380	COG0561	phosphatase activity
FO269_RS01405	COG1175	transmembrane transport
FO269_RS01410	COG0395	ABC-type sugar transport system, permease component
FO269_RS01440	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FO269_RS01455	COG0366	Alpha amylase catalytic
FO269_RS01460	COG1609	Transcriptional regulator
FO269_RS01470	COG0557	exoribonuclease II activity
FO269_RS01480	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FO269_RS01520	COG2390	Transcriptional regulator
FO269_RS01535	COG1846	Transcriptional regulator
FO269_RS01545	COG0391	Required for morphogenesis under gluconeogenic growth conditions
FO269_RS01565	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
FO269_RS01595	COG1136	(ABC) transporter
FO269_RS01600	COG2205	protein histidine kinase activity
FO269_RS01605	COG0745	RESPONSE REGULATOR receiver
FO269_RS01610	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FO269_RS01620	COG0492	ferredoxin-NADP+ reductase activity
FO269_RS01630	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
FO269_RS01640	COG1950	PFAM Membrane protein of
FO269_RS01655	COG0704	Plays a role in the regulation of phosphate uptake
FO269_RS01660	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FO269_RS01665	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FO269_RS01670	COG0581	inorganic phosphate transmembrane transporter activity
FO269_RS01675	COG0573	inorganic phosphate transmembrane transporter activity
FO269_RS01685	COG5002	protein histidine kinase activity
FO269_RS01690	COG0745	RESPONSE REGULATOR receiver
FO269_RS01700	COG2177	Part of the ABC transporter FtsEX involved in
FO269_RS01705	COG2884	Cell division ATP-binding protein ftsE
FO269_RS01710	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
FO269_RS01735	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
FO269_RS01740	COG1739	Uncharacterized protein family UPF0029
FO269_RS01750	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
FO269_RS01765	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
FO269_RS01770	COG1426	Protein conserved in bacteria
FO269_RS01775	COG1028	Short-chain dehydrogenase reductase Sdr
FO269_RS01780	COG0612	Peptidase, M16
FO269_RS01785	COG0612	Peptidase, M16
FO269_RS01790	COG1674	ftsk spoiiie
FO269_RS01800	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
FO269_RS01810	COG2226	methyltransferase
FO269_RS01825	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
FO269_RS01835	COG2706	6-phosphogluconolactonase activity
FO269_RS01845	COG3142	Participates in the control of copper homeostasis
FO269_RS01855	COG0564	pseudouridine synthase activity
FO269_RS01865	COG2357	RelA SpoT domain protein
FO269_RS01890	COG3830	Belongs to the UPF0237 family
FO269_RS01900	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
FO269_RS01905	COG0386	Belongs to the glutathione peroxidase family
FO269_RS01910	COG0438	transferase activity, transferring glycosyl groups
FO269_RS01930	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
FO269_RS01940	COG1187	pseudouridine synthase activity
FO269_RS01945	COG2244	polysaccharide biosynthetic process
FO269_RS01965	COG0671	phosphoesterase, PA-phosphatase related
FO269_RS01975	COG2814	Major facilitator Superfamily
FO269_RS01985	COG0477	Major facilitator Superfamily
FO269_RS02040	COG0735	belongs to the Fur family
FO269_RS02045	COG1368	sulfuric ester hydrolase activity
FO269_RS02060	COG0436	Aminotransferase
FO269_RS02075	COG0438	transferase activity, transferring glycosyl groups
FO269_RS02080	COG0438	transferase activity, transferring glycosyl groups
FO269_RS02085	COG0531	amino acid
FO269_RS02235	COG1098	S1 RNA binding domain
FO269_RS02250	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
FO269_RS02255	COG0586	Pfam SNARE associated Golgi protein
FO269_RS02270	COG0647	UMP catabolic process
FO269_RS02275	COG4470	Protein conserved in bacteria
FO269_RS02280	COG0737	Belongs to the 5'-nucleotidase family
FO269_RS02320	COG1011	Hydrolase
FO269_RS02325	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FO269_RS02330	COG1609	Transcriptional regulator
FO269_RS02335	COG0006	proline dipeptidase activity
FO269_RS02340	COG1827	regulation of RNA biosynthetic process
FO269_RS02360	COG0668	transmembrane transport
FO269_RS02375	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
FO269_RS02385	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
FO269_RS02390	COG1719	4-vinyl reductase, 4VR
FO269_RS02395	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
FO269_RS02405	COG1696	Membrane protein involved in D-alanine export
FO269_RS02420	COG3118	belongs to the thioredoxin family
FO269_RS02475	COG0513	Belongs to the DEAD box helicase family
FO269_RS02480	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
FO269_RS02485	COG4109	DRTGG domain
FO269_RS02490	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FO269_RS02495	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
FO269_RS02510	COG1454	alcohol dehydrogenase
FO269_RS02510	COG1012	belongs to the aldehyde dehydrogenase family
FO269_RS02515	COG1862	Preprotein translocase
FO269_RS02520	COG0343	queuine tRNA-ribosyltransferase activity
FO269_RS02525	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
FO269_RS02550	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
FO269_RS02590	COG2267	carboxylic ester hydrolase activity
FO269_RS02620	COG2267	carboxylic ester hydrolase activity
FO269_RS02625	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
FO269_RS02630	COG0105	UTP biosynthetic process
FO269_RS02635	COG0300	oxidoreductase activity
FO269_RS02650	COG1132	(ABC) transporter
FO269_RS02665	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
FO269_RS02690	COG3189	MarR family transcriptional regulator
FO269_RS02695	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
FO269_RS02710	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FO269_RS02740	COG0628	permease
FO269_RS02755	COG0604	alcohol dehydrogenase
FO269_RS02790	COG1304	FMN binding
FO269_RS02795	COG0778	Nitroreductase
FO269_RS02810	COG1028	Short-chain dehydrogenase reductase Sdr
FO269_RS02815	COG2508	Transcriptional regulator
FO269_RS02825	COG5002	protein histidine kinase activity
FO269_RS02830	COG0745	RESPONSE REGULATOR receiver
FO269_RS02840	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
FO269_RS02845	COG0463	Glycosyl transferase, family 2
FO269_RS02855	COG0604	alcohol dehydrogenase
FO269_RS02865	COG4120	Belongs to the binding-protein-dependent transport system permease family
FO269_RS02885	COG1472	Belongs to the glycosyl hydrolase 3 family
FO269_RS02895	COG2910	NAD(P)H-binding
FO269_RS02910	COG0351	phosphomethylpyrimidine kinase
FO269_RS02930	COG2249	NAD(P)H dehydrogenase (quinone) activity
FO269_RS02940	COG1194	a g-specific adenine glycosylase
FO269_RS02970	COG0419	ATPase involved in DNA repair
FO269_RS02985	COG1349	DNA-binding transcription factor activity
FO269_RS03000	COG3684	Belongs to the aldolase LacD family
FO269_RS03020	COG3775	system Galactitol-specific IIC component
FO269_RS03045	COG2017	converts alpha-aldose to the beta-anomer
FO269_RS03050	COG1609	Transcriptional regulator
FO269_RS03055	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
FO269_RS03060	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FO269_RS03070	COG1447	Phosphotransferase system cellobiose-specific component IIA
FO269_RS03080	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FO269_RS03080	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FO269_RS03085	COG3711	transcriptional antiterminator
FO269_RS03090	COG1215	transferase activity, transferring glycosyl groups
FO269_RS03095	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
FO269_RS03105	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
FO269_RS03110	COG1573	uracil-dna glycosylase
FO269_RS03115	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
FO269_RS03125	COG0488	(ABC) transporter
FO269_RS03140	COG1131	(ABC) transporter
FO269_RS03160	COG1285	pathogenesis
FO269_RS03170	COG0004	ammonium transporteR
FO269_RS03220	COG0025	NhaP-type Na H and K H
FO269_RS03230	COG1113	amino acid transport
FO269_RS03235	COG0656	L-ascorbic acid biosynthetic process
FO269_RS03245	COG0702	epimerase
FO269_RS03250	COG0488	(ABC) transporter
FO269_RS03265	COG1278	Cold shock
FO269_RS03270	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
FO269_RS03280	COG0039	L-malate dehydrogenase activity
FO269_RS03285	COG0531	amino acid
FO269_RS03295	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FO269_RS03295	COG1263	PTS System
FO269_RS03295	COG2190	(PTS) system
FO269_RS03300	COG0366	Alpha amylase catalytic
FO269_RS03305	COG2188	Transcriptional regulator
FO269_RS03310	COG2223	nitrite transmembrane transporter activity
FO269_RS03315	COG1132	(ABC) transporter
FO269_RS03320	COG1132	(ABC) transporter
FO269_RS03330	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
FO269_RS03335	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
FO269_RS03350	COG1131	(ABC) transporter
FO269_RS03360	COG0697	spore germination
FO269_RS03410	COG1114	Component of the transport system for branched-chain amino acids
FO269_RS03420	COG0765	amino acid transport
FO269_RS03425	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FO269_RS03430	COG0626	cystathionine gamma-synthase activity
FO269_RS03445	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FO269_RS03455	COG1174	glycine betaine transport
FO269_RS03490	COG0390	transport system, permease component
FO269_RS03495	COG4619	ABC transporter
FO269_RS03520	COG1309	transcriptional regulator
FO269_RS03530	COG1131	(ABC) transporter
FO269_RS03570	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
FO269_RS03580	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FO269_RS03620	COG3976	FMN-binding domain protein
FO269_RS03620	COG1053	succinate dehydrogenase
FO269_RS03620	COG0431	NADPH-dependent FMN reductase
FO269_RS03635	COG2801	Transposase and inactivated derivatives
FO269_RS03655	COG2801	Transposase and inactivated derivatives
FO269_RS03665	COG0783	Belongs to the Dps family
FO269_RS03700	COG3716	PTS system mannose fructose sorbose family IID component
FO269_RS03705	COG3715	PTS system
FO269_RS03710	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FO269_RS03715	COG2188	Transcriptional regulator
FO269_RS03730	COG0383	alpha-mannosidase activity
FO269_RS03735	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FO269_RS03740	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FO269_RS03740	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FO269_RS03740	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FO269_RS03745	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FO269_RS03745	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FO269_RS03745	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FO269_RS03750	COG3711	transcriptional antiterminator
FO269_RS03750	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FO269_RS03860	COG2197	response regulator
FO269_RS03865	COG4585	Histidine kinase
FO269_RS03950	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
FO269_RS03960	COG0504	CTP synthase activity
FO269_RS03980	COG0095	Lipoate-protein ligase
FO269_RS03985	COG1078	dGTPase activity
FO269_RS04015	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
FO269_RS04020	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
FO269_RS04030	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FO269_RS04035	COG4619	ABC transporter
FO269_RS04040	COG0390	transport system, permease component
FO269_RS04050	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
FO269_RS04055	COG4466	Protein conserved in bacteria
FO269_RS04060	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
FO269_RS04065	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
FO269_RS04070	COG0084	hydrolase, TatD family'
FO269_RS04080	COG3684	Belongs to the aldolase LacD family
FO269_RS04095	COG3290	protein histidine kinase activity
FO269_RS04110	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FO269_RS04110	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FO269_RS04120	COG1801	Protein of unknown function DUF72
FO269_RS04140	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
FO269_RS04155	COG1881	PFAM PEBP family protein
FO269_RS04165	COG4086	secreted protein
FO269_RS04175	COG0248	Ppx GppA phosphatase
FO269_RS04180	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
FO269_RS04195	COG4989	oxidoreductase activity
FO269_RS04200	COG2226	methyltransferase
FO269_RS04210	COG0534	Mate efflux family protein
FO269_RS04215	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
FO269_RS04220	COG1704	LemA family
FO269_RS04235	COG0577	efflux transmembrane transporter activity
FO269_RS04235	COG1136	(ABC) transporter
FO269_RS04240	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FO269_RS04250	COG1174	glycine betaine transport
FO269_RS04260	COG3973	AAA domain
FO269_RS04290	COG1418	mRNA catabolic process
FO269_RS04300	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
FO269_RS04305	COG0667	Aldo Keto reductase
FO269_RS04310	COG0561	phosphatase activity
FO269_RS04335	COG0588	phosphoglycerate mutase activity
FO269_RS04340	COG0561	phosphatase activity
FO269_RS04355	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FO269_RS04360	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
FO269_RS04365	COG1811	Na channel or pump
FO269_RS04390	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FO269_RS04390	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FO269_RS04390	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FO269_RS04395	COG1105	Belongs to the carbohydrate kinase PfkB family
FO269_RS04430	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
FO269_RS04430	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FO269_RS04435	COG3715	PTS system
FO269_RS04440	COG3716	PTS system mannose fructose sorbose family IID component
FO269_RS04445	COG1447	Phosphotransferase system cellobiose-specific component IIA
FO269_RS04455	COG2723	6-phospho-beta-galactosidase activity
FO269_RS04460	COG1940	carbohydrate kinase activity
FO269_RS04475	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FO269_RS04480	COG2188	Transcriptional regulator
FO269_RS04500	COG3775	system Galactitol-specific IIC component
FO269_RS04515	COG1349	DNA-binding transcription factor activity
FO269_RS04535	COG0366	Alpha amylase catalytic
FO269_RS04565	COG0463	Glycosyl transferase, family 2
FO269_RS04575	COG0586	Pfam SNARE associated Golgi protein
FO269_RS04580	COG0745	RESPONSE REGULATOR receiver
FO269_RS04590	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FO269_RS04590	COG1263	PTS System
FO269_RS04625	COG3711	transcriptional antiterminator
FO269_RS04635	COG1263	PTS System
FO269_RS04635	COG2190	(PTS) system
FO269_RS04635	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FO269_RS04675	COG3414	Phosphotransferase system galactitol-specific IIB component
FO269_RS04680	COG3775	system Galactitol-specific IIC component
FO269_RS04705	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
FO269_RS04720	COG2204	response regulator
FO269_RS04745	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FO269_RS04750	COG0800	Aldolase
FO269_RS04770	COG3964	amidohydrolase
FO269_RS04820	COG3732	PTS system glucitol sorbitol-specific
FO269_RS04825	COG3730	PTS system glucitol sorbitol-specific
FO269_RS04835	COG3711	transcriptional antiterminator
FO269_RS04835	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FO269_RS04845	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FO269_RS04845	COG2190	(PTS) system
FO269_RS04845	COG1263	PTS System
FO269_RS04855	COG2723	6-phospho-beta-galactosidase activity
FO269_RS04860	COG1609	Transcriptional regulator
FO269_RS04865	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FO269_RS04865	COG1263	PTS System
FO269_RS04865	COG2190	(PTS) system
FO269_RS04885	COG0561	phosphatase activity
FO269_RS04890	COG3623	hexulose-6-phosphate isomerase
FO269_RS04895	COG1349	DNA-binding transcription factor activity
FO269_RS04900	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
FO269_RS04915	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FO269_RS04935	COG1063	alcohol dehydrogenase
FO269_RS04950	COG3716	PTS system mannose fructose sorbose family IID component
FO269_RS04955	COG3715	PTS system
FO269_RS04960	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FO269_RS04970	COG1063	alcohol dehydrogenase
FO269_RS04975	COG1349	DNA-binding transcription factor activity
FO269_RS04980	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
FO269_RS04990	COG1446	asparaginase
FO269_RS05000	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FO269_RS05005	COG2188	Transcriptional regulator
FO269_RS05030	COG1070	Carbohydrate kinase
FO269_RS05035	COG1063	alcohol dehydrogenase
FO269_RS05040	COG3716	PTS system mannose fructose sorbose family IID component
FO269_RS05050	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FO269_RS05050	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
FO269_RS05060	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FO269_RS05060	COG3711	transcriptional antiterminator
FO269_RS05070	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
FO269_RS05075	COG3775	system Galactitol-specific IIC component
FO269_RS05090	COG0191	fructose-bisphosphate aldolase activity
FO269_RS05095	COG2188	Transcriptional regulator
FO269_RS05110	COG0477	Major facilitator Superfamily
FO269_RS05115	COG0456	acetyltransferase
FO269_RS05150	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FO269_RS05160	COG0395	ABC-type sugar transport system, permease component
FO269_RS05170	COG3842	ATPase activity
FO269_RS05175	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
FO269_RS05180	COG1335	isochorismatase
FO269_RS05195	COG4948	Mandelate Racemase Muconate Lactonizing
FO269_RS05205	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
FO269_RS05215	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FO269_RS05220	COG3716	PTS system mannose fructose sorbose family IID component
FO269_RS05240	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
FO269_RS05250	COG2076	Multidrug Resistance protein
FO269_RS05280	COG0604	alcohol dehydrogenase
FO269_RS05285	COG2365	Tyrosine phosphatase family
FO269_RS05295	COG0789	Transcriptional regulator
FO269_RS05300	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FO269_RS05330	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
FO269_RS05355	COG2217	Heavy metal translocating P-type atpase
FO269_RS05370	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FO269_RS05385	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
FO269_RS05400	COG5002	protein histidine kinase activity
FO269_RS05405	COG0745	RESPONSE REGULATOR receiver
FO269_RS05415	COG0596	Alpha beta hydrolase
FO269_RS05420	COG0765	amino acid transport
FO269_RS05445	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FO269_RS05450	COG2188	Transcriptional regulator
FO269_RS05455	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FO269_RS05460	COG1447	Phosphotransferase system cellobiose-specific component IIA
FO269_RS05485	COG1335	isochorismatase
FO269_RS05495	COG2814	Major facilitator Superfamily
FO269_RS05500	COG2807	transmembrane transport
FO269_RS05505	COG0667	Aldo Keto reductase
FO269_RS05515	COG3716	PTS system mannose fructose sorbose family IID component
FO269_RS05520	COG3715	PTS system
FO269_RS05550	COG0765	amino acid transport
FO269_RS05555	COG1126	abc transporter atp-binding protein
FO269_RS05595	COG4133	protoheme IX ABC transporter activity
FO269_RS05600	COG3001	Fructosamine kinase
FO269_RS05610	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FO269_RS05615	COG0765	amino acid transport
FO269_RS05630	COG0714	Associated with various cellular activities
FO269_RS05640	COG1305	Transglutaminase-like
FO269_RS05645	COG0438	transferase activity, transferring glycosyl groups
FO269_RS05650	COG0110	maltose O-acetyltransferase activity
FO269_RS05655	COG0561	phosphatase activity
FO269_RS05680	COG3493	citrate carrier protein
FO269_RS05685	COG3290	protein histidine kinase activity
FO269_RS05690	COG4565	transcriptional regulatory protein
FO269_RS05750	COG1263	PTS System
FO269_RS05750	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FO269_RS05755	COG2190	(PTS) system
FO269_RS05755	COG1263	PTS System
FO269_RS05755	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FO269_RS05760	COG3711	transcriptional antiterminator
FO269_RS05775	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
FO269_RS05795	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
FO269_RS05805	COG2213	PTS system mannitol-specific
FO269_RS05820	COG0561	phosphatase activity
FO269_RS05845	COG0577	efflux transmembrane transporter activity
FO269_RS05845	COG1136	(ABC) transporter
FO269_RS05850	COG0577	efflux transmembrane transporter activity
FO269_RS05860	COG2723	6-phospho-beta-galactosidase activity
FO269_RS05865	COG1263	PTS System
FO269_RS05865	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FO269_RS05865	COG2190	(PTS) system
FO269_RS05870	COG3711	transcriptional antiterminator
FO269_RS05875	COG0371	Dehydrogenase
FO269_RS05880	COG1473	amidohydrolase
FO269_RS05920	COG0706	membrane insertase activity
FO269_RS05945	COG0592	DNA-directed DNA polymerase activity
FO269_RS05955	COG2501	S4 domain
FO269_RS05970	COG0187	DNA topoisomerase II activity
FO269_RS05980	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
FO269_RS05995	COG0629	single-stranded DNA binding
FO269_RS06005	COG1271	oxidase subunit
FO269_RS06010	COG1294	oxidase, subunit
FO269_RS06060	COG3942	CHAP domain
FO269_RS06080	COG0561	phosphatase activity
FO269_RS06100	COG3409	Peptidoglycan-binding domain 1 protein
FO269_RS06230	COG0800	Aldolase
FO269_RS06255	COG1132	(ABC) transporter
FO269_RS06260	COG2814	Major facilitator Superfamily
FO269_RS06270	COG2409	Drug exporters of the RND superfamily
FO269_RS06270	COG1033	growth of symbiont in host cell
FO269_RS06275	COG1309	transcriptional regulator
FO269_RS06290	COG1732	Glycine betaine
FO269_RS06330	COG2217	Heavy metal translocating P-type atpase
FO269_RS06340	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FO269_RS06345	COG0159	tryptophan synthase activity
FO269_RS06350	COG0133	tryptophan synthase activity
FO269_RS06355	COG0135	phosphoribosylanthranilate isomerase activity
FO269_RS06360	COG0134	indole-3-glycerol-phosphate synthase activity
FO269_RS06385	COG2814	Major facilitator Superfamily
FO269_RS06420	COG1131	(ABC) transporter
FO269_RS06445	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
FO269_RS06465	COG0019	diaminopimelate decarboxylase activity
FO269_RS06470	COG0527	aspartate kinase activity
FO269_RS06475	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
FO269_RS06480	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
FO269_RS06530	COG0305	Participates in initiation and elongation during chromosome replication
FO269_RS06545	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
FO269_RS06550	COG1737	Transcriptional regulator
FO269_RS06555	COG1309	transcriptional regulator
FO269_RS06560	COG1136	(ABC) transporter
FO269_RS06560	COG0577	efflux transmembrane transporter activity
FO269_RS06580	COG2217	Heavy metal translocating P-type atpase
FO269_RS06585	COG0640	Transcriptional regulator
FO269_RS06590	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
FO269_RS06595	COG0583	DNA-binding transcription factor activity
FO269_RS06600	COG3620	sequence-specific DNA binding
FO269_RS06610	COG1131	(ABC) transporter
FO269_RS06620	COG1328	CTP reductase activity
FO269_RS06675	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FO269_RS06705	COG2252	PERMEase
FO269_RS06720	COG1116	anion transmembrane transporter activity
FO269_RS06725	COG4521	taurine ABC transporter
FO269_RS06730	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FO269_RS06735	COG0446	pyridine nucleotide-disulphide oxidoreductase
FO269_RS06740	COG2391	methyltransferase activity
FO269_RS06755	COG0346	lactoylglutathione lyase activity
FO269_RS06815	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
FO269_RS06840	COG1511	domain protein
FO269_RS06840	COG1511	domain protein
FO269_RS06850	COG0477	Major facilitator Superfamily
FO269_RS06860	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
FO269_RS06865	COG4166	transmembrane transport
FO269_RS06885	COG1131	(ABC) transporter
FO269_RS06925	COG1396	sequence-specific DNA binding
FO269_RS06940	COG0446	pyridine nucleotide-disulphide oxidoreductase
FO269_RS06980	COG0716	FMN binding
FO269_RS06995	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FO269_RS07005	COG2261	transglycosylase associated protein
FO269_RS07020	COG1302	Protein conserved in bacteria
FO269_RS07060	COG3442	glutamine amidotransferase
FO269_RS07080	COG1192	Involved in chromosome partitioning
FO269_RS07085	COG1475	DNA binding
FO269_RS07090	COG4481	Protein conserved in bacteria
FO269_RS07095	COG0012	GTP binding
FO269_RS07105	COG0516	GMP reductase activity
FO269_RS07105	COG0517	IMP dehydrogenase activity
FO269_RS07125	COG1686	Belongs to the peptidase S11 family
FO269_RS07130	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FO269_RS07140	COG1794	racemase activity, acting on amino acids and derivatives
FO269_RS07145	COG0656	L-ascorbic acid biosynthetic process
FO269_RS07150	COG1349	DNA-binding transcription factor activity
FO269_RS07155	COG2814	Major facilitator Superfamily
FO269_RS07160	COG1012	belongs to the aldehyde dehydrogenase family
FO269_RS07165	COG3718	enzyme involved in inositol metabolism
FO269_RS07170	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FO269_RS07175	COG3962	Belongs to the TPP enzyme family
FO269_RS07180	COG0673	inositol 2-dehydrogenase activity
FO269_RS07185	COG0673	inositol 2-dehydrogenase activity
FO269_RS07195	COG0191	fructose-bisphosphate aldolase activity
FO269_RS07200	COG1942	4-Oxalocrotonate Tautomerase
FO269_RS07205	COG1737	Transcriptional regulator
FO269_RS07210	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
FO269_RS07220	COG2610	gluconate transmembrane transporter activity
FO269_RS07230	COG1121	(ABC) transporter
FO269_RS07245	COG2084	Dehydrogenase
FO269_RS07250	COG1164	Oligoendopeptidase f
FO269_RS07255	COG1316	TRANSCRIPTIONal
FO269_RS07260	COG1114	Component of the transport system for branched-chain amino acids
FO269_RS07275	COG1216	Glycosyl transferase, family 2
FO269_RS07300	COG0488	(ABC) transporter
FO269_RS07325	COG3118	belongs to the thioredoxin family
FO269_RS07345	COG0683	leucine binding
FO269_RS07375	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FO269_RS07385	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
FO269_RS07390	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
FO269_RS07415	COG2723	6-phospho-beta-galactosidase activity
FO269_RS07420	COG0446	pyridine nucleotide-disulphide oxidoreductase
FO269_RS07440	COG2182	Extracellular solute-binding protein
FO269_RS07450	COG3064	Membrane
FO269_RS07450	COG3583	domain protein
FO269_RS07450	COG3525	Glycosyl hydrolase, family 20, catalytic domain
FO269_RS07455	COG1482	cell wall glycoprotein biosynthetic process
FO269_RS07460	COG2188	Transcriptional regulator
FO269_RS07465	COG2222	sugar isomerase
FO269_RS07470	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
FO269_RS07485	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FO269_RS07490	COG3715	PTS system
FO269_RS07495	COG3716	PTS system mannose fructose sorbose family IID component
FO269_RS07500	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
FO269_RS07500	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FO269_RS07510	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
FO269_RS07515	COG0006	proline dipeptidase activity
FO269_RS07525	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FO269_RS07530	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FO269_RS07535	COG1447	Phosphotransferase system cellobiose-specific component IIA
FO269_RS07545	COG1363	Peptidase, m42
FO269_RS07555	COG2195	Cleaves the N-terminal amino acid of tripeptides
FO269_RS07560	COG4166	transmembrane transport
FO269_RS07585	COG1129	ABC transporter
FO269_RS07595	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
FO269_RS07615	COG0351	phosphomethylpyrimidine kinase
FO269_RS07630	COG1609	Transcriptional regulator
FO269_RS07645	COG1172	Belongs to the binding-protein-dependent transport system permease family
FO269_RS07650	COG1879	ABC-type sugar transport system periplasmic component
FO269_RS07670	COG2814	Major facilitator Superfamily
FO269_RS07710	COG1131	(ABC) transporter
FO269_RS07730	COG1053	succinate dehydrogenase
FO269_RS07735	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FO269_RS07770	COG1378	Sugar-specific transcriptional regulator TrmB
FO269_RS07785	COG2267	carboxylic ester hydrolase activity
FO269_RS07835	COG1609	Transcriptional regulator
FO269_RS07845	COG3716	PTS system mannose fructose sorbose family IID component
FO269_RS07865	COG0641	radical SAM
FO269_RS07875	COG3716	PTS system mannose fructose sorbose family IID component
FO269_RS07880	COG3715	PTS system
FO269_RS07885	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FO269_RS07905	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
FO269_RS07910	COG3711	transcriptional antiterminator
FO269_RS07915	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FO269_RS07915	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
FO269_RS07925	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FO269_RS07925	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FO269_RS07925	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FO269_RS07930	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FO269_RS07935	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FO269_RS07935	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FO269_RS07935	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FO269_RS07955	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FO269_RS07955	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FO269_RS07955	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FO269_RS07960	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FO269_RS07960	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FO269_RS07965	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
FO269_RS07980	COG0191	fructose-bisphosphate aldolase activity
FO269_RS07985	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FO269_RS07985	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FO269_RS07985	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FO269_RS07990	COG1028	Short-chain dehydrogenase reductase Sdr
FO269_RS08000	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
FO269_RS08000	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FO269_RS08005	COG3715	PTS system
FO269_RS08010	COG3716	PTS system mannose fructose sorbose family IID component
FO269_RS08015	COG0246	Mannitol dehydrogenase
FO269_RS08020	COG1461	Dihydroxyacetone kinase
FO269_RS08025	COG2376	Dihydroxyacetone kinase
FO269_RS08030	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
FO269_RS08035	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
FO269_RS08040	COG1609	Transcriptional regulator
FO269_RS08050	COG2390	Transcriptional regulator
FO269_RS08060	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
FO269_RS08065	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FO269_RS08070	COG3715	PTS system
FO269_RS08075	COG3716	PTS system mannose fructose sorbose family IID component
FO269_RS08080	COG0191	fructose-bisphosphate aldolase activity
FO269_RS08085	COG0471	metal ion transport
FO269_RS08095	COG0583	DNA-binding transcription factor activity
FO269_RS08110	COG1122	ATPase activity
FO269_RS08160	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FO269_RS08165	COG1349	DNA-binding transcription factor activity
FO269_RS08170	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
FO269_RS08175	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
FO269_RS08180	COG1349	DNA-binding transcription factor activity
FO269_RS08210	COG0477	Major facilitator Superfamily
FO269_RS08230	COG4221	oxidoreductase activity
FO269_RS08255	COG0446	pyridine nucleotide-disulphide oxidoreductase
FO269_RS08260	COG0561	phosphatase activity
FO269_RS08270	COG1609	Transcriptional regulator
FO269_RS08275	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FO269_RS08285	COG3716	PTS system mannose fructose sorbose family IID component
FO269_RS08300	COG0366	Alpha amylase catalytic
FO269_RS08330	COG1464	Belongs to the NlpA lipoprotein family
FO269_RS08360	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
FO269_RS08365	COG1461	Dihydroxyacetone kinase
FO269_RS08370	COG2376	Dihydroxyacetone kinase
FO269_RS08395	COG2814	Major facilitator Superfamily
FO269_RS08415	COG0028	Belongs to the TPP enzyme family
FO269_RS08430	COG2226	methyltransferase
FO269_RS08435	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
FO269_RS08440	COG0174	glutamine synthetase
FO269_RS08455	COG0789	Transcriptional regulator
FO269_RS08460	COG0656	L-ascorbic acid biosynthetic process
FO269_RS08475	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
FO269_RS08500	COG1131	(ABC) transporter
FO269_RS08520	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FO269_RS08560	COG0308	aminopeptidase N
FO269_RS08565	COG0531	amino acid
FO269_RS08585	COG1028	Short-chain dehydrogenase reductase Sdr
FO269_RS08595	COG2271	Major facilitator Superfamily
FO269_RS08600	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
FO269_RS08605	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
FO269_RS08610	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FO269_RS08665	COG1396	sequence-specific DNA binding
FO269_RS08800	COG2826	transposase and inactivated derivatives, IS30 family
FO269_RS08845	COG0366	Alpha amylase catalytic
FO269_RS08860	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FO269_RS08865	COG3842	ATPase activity
FO269_RS08870	COG0366	Alpha amylase catalytic
FO269_RS08880	COG1175	transmembrane transport
FO269_RS08885	COG3833	ABC-type maltose transport systems, permease component
FO269_RS08890	COG1609	Transcriptional regulator
FO269_RS08900	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
FO269_RS08905	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
FO269_RS08955	COG1511	domain protein
FO269_RS09015	COG0277	FAD linked oxidase domain protein
FO269_RS09030	COG0318	PFAM AMP-dependent synthetase and ligase
FO269_RS09035	COG2271	Major facilitator Superfamily
FO269_RS09075	COG2826	transposase and inactivated derivatives, IS30 family
FO269_RS09090	COG0741	lytic transglycosylase activity
FO269_RS09090	COG0791	NLP P60 protein
FO269_RS09100	COG0433	COG0433 Predicted ATPase
FO269_RS09130	COG2946	Replication initiation factor
FO269_RS09145	COG1674	ftsk spoiiie
FO269_RS09225	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
FO269_RS09250	COG2337	Toxic component of a toxin-antitoxin (TA) module
FO269_RS09255	COG4708	membrane
FO269_RS09265	COG0069	glutamate synthase activity
FO269_RS09265	COG0067	glutamate synthase
FO269_RS09265	COG0070	glutamate synthase
FO269_RS09275	COG0493	'glutamate synthase
FO269_RS09280	COG1376	ErfK ybiS ycfS ynhG family protein
FO269_RS09310	COG0039	L-malate dehydrogenase activity
FO269_RS09320	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
FO269_RS09325	COG2244	polysaccharide biosynthetic process
FO269_RS09330	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
FO269_RS09340	COG1098	S1 RNA binding domain
FO269_RS09345	COG0037	tRNA processing
FO269_RS09350	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
FO269_RS09390	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FO269_RS09395	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
FO269_RS09465	COG4463	regulation of RNA biosynthetic process
FO269_RS09470	COG0542	response to heat
FO269_RS09525	COG0450	alkyl hydroperoxide reductase
FO269_RS09635	COG0200	Binds to the 23S rRNA
FO269_RS09715	COG0789	Transcriptional regulator
FO269_RS09730	COG1136	(ABC) transporter
FO269_RS09735	COG0577	efflux transmembrane transporter activity
FO269_RS09775	COG4555	ABC transporter
FO269_RS09790	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FO269_RS09795	COG1116	anion transmembrane transporter activity
FO269_RS09815	COG3639	organic phosphonate transmembrane transporter activity
FO269_RS09835	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
FO269_RS09840	COG0148	phosphopyruvate hydratase activity
FO269_RS09855	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
FO269_RS09950	COG1012	belongs to the aldehyde dehydrogenase family
FO269_RS09955	COG1121	(ABC) transporter
FO269_RS09960	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FO269_RS09995	COG2814	Major facilitator Superfamily
FO269_RS10005	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
FO269_RS10010	COG1914	H( )-stimulated, divalent metal cation uptake system
FO269_RS10025	COG0114	fumarate hydratase activity
FO269_RS10035	COG4221	oxidoreductase activity
FO269_RS10045	COG4989	oxidoreductase activity
FO269_RS10070	COG0110	maltose O-acetyltransferase activity
FO269_RS10150	COG2274	protein secretion by the type I secretion system
FO269_RS10155	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FO269_RS10200	COG1695	Transcriptional regulator
FO269_RS10240	COG3764	Sortase (surface protein transpeptidase)
FO269_RS10265	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
FO269_RS10305	COG1304	FMN binding
FO269_RS10320	COG0588	phosphoglycerate mutase activity
FO269_RS10325	COG0517	IMP dehydrogenase activity
FO269_RS10330	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FO269_RS10330	COG0574	Belongs to the PEP-utilizing enzyme family
FO269_RS10340	COG1131	(ABC) transporter
FO269_RS10370	COG3152	Membrane
FO269_RS10375	COG2388	GCN5-related N-acetyl-transferase
FO269_RS10380	COG0756	dUTP diphosphatase activity
FO269_RS10385	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
FO269_RS10390	COG4956	integral membrane protein (PIN domain superfamily)
FO269_RS10425	COG4886	Leucine-rich repeat (LRR) protein
FO269_RS10425	COG4932	domain protein
FO269_RS10440	COG4377	Putative membrane peptidase family (DUF2324)
FO269_RS10445	COG1737	Transcriptional regulator
FO269_RS10450	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
FO269_RS10480	COG0277	FAD linked oxidase domain protein
FO269_RS10495	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
FO269_RS10500	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FO269_RS10505	COG3688	RNA-binding protein containing a PIN domain
FO269_RS10580	COG4939	FMN-binding domain protein
FO269_RS10610	COG0250	Participates in transcription elongation, termination and antitermination
FO269_RS10640	COG2096	Adenosyltransferase
FO269_RS10645	COG5646	InterPro IPR014922
FO269_RS10655	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
FO269_RS10670	COG1012	belongs to the aldehyde dehydrogenase family
FO269_RS10675	COG0477	Major facilitator Superfamily
FO269_RS10725	COG1609	Transcriptional regulator
FO269_RS10735	COG0392	lysyltransferase activity
FO269_RS10735	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
FO269_RS10740	COG2813	Specifically methylates the guanine in position
FO269_RS10750	COG0590	tRNA wobble adenosine to inosine editing
FO269_RS10765	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
FO269_RS10800	COG3870	Protein conserved in bacteria
FO269_RS10805	COG0470	DNA polymerase III
FO269_RS10855	COG1214	PFAM Peptidase M22, glycoprotease
FO269_RS10860	COG1214	PFAM Peptidase M22, glycoprotease
FO269_RS10860	COG0456	acetyltransferase
FO269_RS10870	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FO269_RS10885	COG0488	(ABC) transporter
FO269_RS10890	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
FO269_RS10895	COG1725	Transcriptional regulator
FO269_RS10900	COG1131	(ABC) transporter
FO269_RS10910	COG1316	TRANSCRIPTIONal
FO269_RS10915	COG1266	CAAX protease self-immunity
FO269_RS10940	COG0531	amino acid
FO269_RS10975	COG2814	Major facilitator Superfamily
FO269_RS10980	COG1253	flavin adenine dinucleotide binding
FO269_RS10990	COG0505	Belongs to the CarA family
FO269_RS11000	COG2264	protein methyltransferase activity
FO269_RS11025	COG1063	alcohol dehydrogenase
FO269_RS11035	COG0789	Transcriptional regulator
FO269_RS11040	COG1268	BioY protein
FO269_RS11050	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
FO269_RS11055	COG2365	Tyrosine phosphatase family
FO269_RS11070	COG2818	Glycosylase
FO269_RS11075	COG0697	spore germination
FO269_RS11105	COG1271	oxidase subunit
FO269_RS11110	COG1294	oxidase, subunit
FO269_RS11115	COG4988	ABC transporter
FO269_RS11120	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
FO269_RS11150	COG1518	maintenance of DNA repeat elements
FO269_RS11180	COG1132	(ABC) transporter
FO269_RS11185	COG1132	(ABC) transporter
FO269_RS11195	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FO269_RS11195	COG2190	(PTS) system
FO269_RS11195	COG1263	PTS System
FO269_RS11200	COG2723	6-phospho-beta-galactosidase activity
FO269_RS11215	COG0477	Major facilitator Superfamily
FO269_RS11235	COG1297	OPT oligopeptide transporter protein
FO269_RS11275	COG4152	abc transporter atp-binding protein
FO269_RS11285	COG0142	geranyltranstransferase activity
FO269_RS11300	COG0367	asparagine synthase
FO269_RS11325	COG0436	Aminotransferase
FO269_RS11330	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FO269_RS11345	COG2268	Band 7 protein
FO269_RS11350	COG0527	aspartate kinase activity
FO269_RS11355	COG0460	homoserine dehydrogenase
FO269_RS11400	COG0028	Belongs to the TPP enzyme family
FO269_RS11405	COG1597	lipid kinase activity
FO269_RS11425	COG0628	permease
FO269_RS11445	COG0588	phosphoglycerate mutase activity
FO269_RS11455	COG0494	nUDIX hydrolase
FO269_RS11460	COG1132	(ABC) transporter
FO269_RS11465	COG1846	Transcriptional regulator
FO269_RS11510	COG1979	alcohol dehydrogenase
FO269_RS11530	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FO269_RS11540	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FO269_RS11545	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FO269_RS11560	COG1028	Short-chain dehydrogenase reductase Sdr
FO269_RS11565	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FO269_RS11570	COG0511	ligase activity, forming carbon-carbon bonds
FO269_RS11585	COG0439	Biotin carboxylase
FO269_RS11600	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FO269_RS11605	COG0702	epimerase
FO269_RS11620	COG1609	Transcriptional regulator
FO269_RS11625	COG0366	Alpha amylase catalytic
FO269_RS11630	COG1263	PTS System
FO269_RS11630	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FO269_RS11630	COG2190	(PTS) system
FO269_RS11690	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FO269_RS11740	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FO269_RS11760	COG1447	Phosphotransferase system cellobiose-specific component IIA
FO269_RS11800	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
FO269_RS11805	COG2814	Major facilitator Superfamily
FO269_RS11810	COG4166	transmembrane transport
FO269_RS11815	COG0601	transmembrane transport
FO269_RS11820	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FO269_RS11825	COG0444	Belongs to the ABC transporter superfamily
FO269_RS11830	COG4608	Belongs to the ABC transporter superfamily
FO269_RS11855	COG1028	Short-chain dehydrogenase reductase Sdr
FO269_RS11860	COG4708	membrane
FO269_RS11875	COG0489	protein tyrosine kinase activity
FO269_RS11885	COG0438	transferase activity, transferring glycosyl groups
FO269_RS11905	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
FO269_RS11910	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
FO269_RS11915	COG1088	dTDP-glucose 4,6-dehydratase activity
FO269_RS11920	COG1091	dTDP-4-dehydrorhamnose reductase activity
FO269_RS11925	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FO269_RS11960	COG1316	TRANSCRIPTIONal
FO269_RS11965	COG4464	protein tyrosine phosphatase activity
FO269_RS11975	COG1393	Belongs to the ArsC family
FO269_RS11990	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FO269_RS12000	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FO269_RS12005	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
FO269_RS12015	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
FO269_RS12025	COG0058	SHG alpha-glucan phosphorylase activity
FO269_RS12050	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FO269_RS12060	COG0454	-acetyltransferase
FO269_RS12060	COG0456	acetyltransferase
FO269_RS12065	COG0194	GDP metabolic process
FO269_RS12075	COG0735	belongs to the Fur family
FO269_RS12095	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FO269_RS12100	COG0765	amino acid transport
FO269_RS12105	COG0765	amino acid transport
FO269_RS12115	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FO269_RS12150	COG1376	ErfK ybiS ycfS ynhG family protein
FO269_RS12160	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FO269_RS12170	COG3475	LICD family
FO269_RS12185	COG1216	Glycosyl transferase, family 2
FO269_RS12195	COG0438	transferase activity, transferring glycosyl groups
FO269_RS12235	COG0726	polysaccharide deacetylase
FO269_RS12240	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
FO269_RS12250	COG0531	amino acid
FO269_RS12255	COG1136	(ABC) transporter
FO269_RS12290	COG2267	carboxylic ester hydrolase activity
FO269_RS12295	COG0569	domain protein
FO269_RS12295	COG0475	glutathione-regulated potassium exporter activity
FO269_RS12310	COG3973	AAA domain
FO269_RS12315	COG1607	acyl-coa hydrolase
FO269_RS12320	COG4690	dipeptidase activity
FO269_RS12345	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
FO269_RS12350	COG0732	type I restriction modification DNA specificity domain
FO269_RS12355	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
FO269_RS12435	COG0270	DNA (cytosine-5-)-methyltransferase activity
FO269_RS12450	COG1349	DNA-binding transcription factor activity
FO269_RS12460	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FO269_RS12460	COG5549	protein import
FO269_RS12485	COG1132	(ABC) transporter
FO269_RS12500	COG0640	Transcriptional regulator
FO269_RS12510	COG4166	transmembrane transport
FO269_RS12515	COG0601	transmembrane transport
FO269_RS12525	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FO269_RS12535	COG0444	Belongs to the ABC transporter superfamily
FO269_RS12540	COG4608	Belongs to the ABC transporter superfamily
FO269_RS12550	COG1136	(ABC) transporter
FO269_RS12565	COG1131	(ABC) transporter
FO269_RS12570	COG1725	Transcriptional regulator
FO269_RS12590	COG2814	Major facilitator Superfamily
FO269_RS12605	COG1131	(ABC) transporter
FO269_RS12645	COG2851	Citrate transporter
FO269_RS12655	COG0511	ligase activity, forming carbon-carbon bonds
FO269_RS12690	COG3697	Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase
FO269_RS12690	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
FO269_RS12710	COG3697	Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase
FO269_RS12710	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
FO269_RS12730	COG0564	pseudouridine synthase activity
FO269_RS12755	COG0519	Catalyzes the synthesis of GMP from XMP
FO269_RS12765	COG0028	Belongs to the TPP enzyme family
FO269_RS12780	COG0833	amino acid
FO269_RS12895	COG0577	efflux transmembrane transporter activity
FO269_RS12895	COG1136	(ABC) transporter
FO269_RS12905	COG3104	oligopeptide transport
FO269_RS12920	COG1506	peptidase
FO269_RS12920	COG0823	Involved in the tonB-independent uptake of proteins
FO269_RS12920	COG4946	Tricorn protease homolog
FO269_RS12925	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FO269_RS12935	COG2188	Transcriptional regulator
FO269_RS12945	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
FO269_RS12980	COG4120	Belongs to the binding-protein-dependent transport system permease family
FO269_RS12985	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
FO269_RS12990	COG3091	SprT-like family
FO269_RS13010	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FO269_RS13035	COG0183	Belongs to the thiolase family
FO269_RS13045	COG3425	synthase
FO269_RS13050	COG0028	Belongs to the TPP enzyme family
FO269_RS13060	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FO269_RS13065	COG1447	Phosphotransferase system cellobiose-specific component IIA
FO269_RS13075	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FO269_RS13080	COG2723	6-phospho-beta-galactosidase activity
FO269_RS13085	COG2188	Transcriptional regulator
FO269_RS13100	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FO269_RS13125	COG3557	Belongs to the UPF0374 family
FO269_RS13140	COG0628	permease
FO269_RS13145	COG1253	flavin adenine dinucleotide binding
FO269_RS13160	COG0542	response to heat
FO269_RS13170	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FO269_RS13180	COG2814	Major facilitator Superfamily
FO269_RS13190	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
FO269_RS13195	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
FO269_RS13205	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FO269_RS13225	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
FO269_RS13230	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
FO269_RS13240	COG0151	Belongs to the GarS family
FO269_RS13255	COG3682	Transcriptional regulator
FO269_RS13260	COG2217	Heavy metal translocating P-type atpase
FO269_RS13270	COG0642	Histidine kinase
FO269_RS13275	COG0745	RESPONSE REGULATOR receiver
FO269_RS13280	COG1136	(ABC) transporter
FO269_RS13295	COG1234	tRNA 3'-trailer cleavage
FO269_RS13300	COG1393	Belongs to the ArsC family
FO269_RS13320	COG0167	dihydroorotate dehydrogenase activity
FO269_RS13345	COG0018	arginyl-trna synthetase
FO269_RS13355	COG1438	arginine binding
FO269_RS13360	COG0564	pseudouridine synthase activity
FO269_RS13365	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FO269_RS13380	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FO269_RS13390	COG0537	adenosine 5'-monophosphoramidase activity
FO269_RS13395	COG1131	(ABC) transporter
FO269_RS13420	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FO269_RS13425	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FO269_RS13430	COG1674	ftsk spoiiie
FO269_RS13440	COG0670	Belongs to the BI1 family
FO269_RS13445	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FO269_RS13445	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FO269_RS13450	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
FO269_RS13455	COG0237	dephospho-CoA kinase activity
FO269_RS13465	COG3611	Membrane attachment protein
FO269_RS13470	COG1484	DNA-dependent DNA replication
FO269_RS13500	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
FO269_RS13525	COG0400	carboxylic ester hydrolase activity
FO269_RS13535	COG0346	lactoylglutathione lyase activity
FO269_RS13540	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
FO269_RS13545	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
FO269_RS13550	COG1534	Rna-binding protein
FO269_RS13555	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
FO269_RS13565	COG0799	negative regulation of ribosome biogenesis
FO269_RS13570	COG2226	methyltransferase
FO269_RS13595	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
FO269_RS13600	COG0745	RESPONSE REGULATOR receiver
FO269_RS13605	COG5002	protein histidine kinase activity
FO269_RS13610	COG0706	membrane insertase activity
FO269_RS13620	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FO269_RS13630	COG1733	regulation of RNA biosynthetic process
FO269_RS13645	COG0072	phenylalanine-tRNA ligase activity
FO269_RS13655	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
FO269_RS13660	COG0572	uridine kinase
FO269_RS13665	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FO269_RS13680	COG2197	response regulator
FO269_RS13685	COG4841	protein insertion into membrane
FO269_RS13695	COG0768	penicillin binding
FO269_RS13700	COG0705	Rhomboid family
FO269_RS13700	COG0457	Tetratricopeptide repeat
FO269_RS13710	COG1940	carbohydrate kinase activity
FO269_RS13715	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FO269_RS13730	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
FO269_RS13735	COG1982	Orn Lys Arg decarboxylase major
FO269_RS13740	COG0789	Transcriptional regulator
FO269_RS13775	COG0261	This protein binds to 23S rRNA in the presence of protein L20
FO269_RS13780	COG2868	ribosomal protein
FO269_RS13785	COG0211	Belongs to the bacterial ribosomal protein bL27 family
FO269_RS13790	COG0006	proline dipeptidase activity
FO269_RS13795	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
FO269_RS13800	COG1302	Protein conserved in bacteria
FO269_RS13820	COG1722	exodeoxyribonuclease VII activity
FO269_RS13825	COG0142	geranyltranstransferase activity
FO269_RS13830	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
FO269_RS13835	COG1438	arginine binding
FO269_RS13840	COG0497	DNA recombination
FO269_RS13860	COG0194	GDP metabolic process
FO269_RS13870	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
FO269_RS13875	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
FO269_RS13885	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FO269_RS13885	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FO269_RS13895	COG2815	serine threonine protein kinase
FO269_RS13895	COG0515	serine threonine protein kinase
FO269_RS13900	COG1162	GTPase activity
FO269_RS13905	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
FO269_RS13910	COG1564	THIamine pyrophosphokinase
FO269_RS13930	COG1461	Dihydroxyacetone kinase
FO269_RS13935	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
FO269_RS13945	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FO269_RS13955	COG4608	Belongs to the ABC transporter superfamily
FO269_RS13960	COG0601	transmembrane transport
FO269_RS13965	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FO269_RS13975	COG0571	ribonuclease III activity
FO269_RS13980	COG1196	nuclear chromosome segregation
FO269_RS13985	COG0552	protein localization to endoplasmic reticulum
FO269_RS14000	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
FO269_RS14010	COG1837	Belongs to the UPF0109 family
FO269_RS14035	COG4224	UPF0291 protein
FO269_RS14040	COG3763	UPF0154 protein
FO269_RS14045	COG1132	(ABC) transporter
FO269_RS14050	COG1132	(ABC) transporter
FO269_RS14060	COG0531	amino acid
FO269_RS14065	COG0204	Acyl-transferase
FO269_RS14070	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
FO269_RS14100	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
FO269_RS14105	COG4589	Belongs to the CDS family
FO269_RS14110	COG0750	zinc metalloprotease
FO269_RS14130	COG0195	Participates in both transcription termination and antitermination
FO269_RS14135	COG2740	Nucleic-acid-binding protein implicated in transcription termination
FO269_RS14160	COG0861	Integral membrane protein TerC family
FO269_RS14170	COG0196	riboflavin kinase activity
FO269_RS14175	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FO269_RS14185	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
FO269_RS14205	COG1132	(ABC) transporter
FO269_RS14235	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
FO269_RS14235	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
FO269_RS14250	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
FO269_RS14310	COG0438	transferase activity, transferring glycosyl groups
FO269_RS14315	COG0673	inositol 2-dehydrogenase activity
FO269_RS14350	COG2094	Belongs to the DNA glycosylase MPG family
FO269_RS14365	COG1385	rRNA (uridine-N3-)-methyltransferase activity
FO269_RS14375	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FO269_RS14390	COG0860	N-Acetylmuramoyl-L-alanine amidase
FO269_RS14390	COG3103	Sh3 type 3 domain protein
FO269_RS14390	COG4991	sh3 domain protein
FO269_RS14400	COG1131	(ABC) transporter
FO269_RS14435	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FO269_RS14440	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FO269_RS14445	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
FO269_RS14460	COG1610	YqeY-like protein
FO269_RS14465	COG1702	phosphate starvation-inducible protein PhoH
FO269_RS14480	COG0295	cytidine deaminase activity
FO269_RS14490	COG1381	Involved in DNA repair and RecF pathway recombination
FO269_RS14520	COG0358	DNA primase activity
FO269_RS14525	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FO269_RS14530	COG2384	SAM-dependent methyltransferase
FO269_RS14535	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
FO269_RS14540	COG1942	4-Oxalocrotonate Tautomerase
FO269_RS14545	COG2151	metal-sulfur cluster biosynthetic enzyme
FO269_RS14560	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FO269_RS14560	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
FO269_RS14600	COG1199	ATP-dependent helicase activity
FO269_RS14600	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FO269_RS14610	COG0436	Aminotransferase
FO269_RS14625	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
FO269_RS14630	COG2131	deaminase
FO269_RS14635	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FO269_RS14665	COG0116	Belongs to the methyltransferase superfamily
FO269_RS14680	COG0095	Lipoate-protein ligase
FO269_RS14685	COG3590	peptidase
FO269_RS14690	COG0583	DNA-binding transcription factor activity
FO269_RS14700	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FO269_RS14705	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FO269_RS14710	COG1393	Belongs to the ArsC family
FO269_RS14725	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FO269_RS14735	COG0328	RNA-DNA hybrid ribonuclease activity
FO269_RS14750	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
FO269_RS14755	COG0564	pseudouridine synthase activity
FO269_RS14760	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
FO269_RS14765	COG2233	PERMEase
FO269_RS14775	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
FO269_RS14780	COG0505	Belongs to the CarA family
FO269_RS14795	COG0284	orotidine-5'-phosphate decarboxylase activity
FO269_RS14800	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
FO269_RS14805	COG0280	phosphate acetyltransferase
FO269_RS14810	COG3426	butyrate kinase activity
FO269_RS14815	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FO269_RS14820	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
FO269_RS14825	COG0022	dehydrogenase e1 component
FO269_RS14830	COG0508	dehydrogenase complex catalyzes the overall conversion of
FO269_RS14835	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
FO269_RS14850	COG1293	RNA-binding protein homologous to eukaryotic snRNP
FO269_RS14855	COG1307	EDD domain protein, DegV family
FO269_RS14860	COG0494	nUDIX hydrolase
FO269_RS14865	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FO269_RS14880	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
FO269_RS14915	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FO269_RS14920	COG0778	Nitroreductase
FO269_RS14940	COG0745	RESPONSE REGULATOR receiver
FO269_RS14945	COG5002	protein histidine kinase activity
FO269_RS14950	COG1136	(ABC) transporter
FO269_RS14955	COG0577	efflux transmembrane transporter activity
FO269_RS14965	COG4974	Belongs to the 'phage' integrase family
FO269_RS14970	COG1227	inorganic diphosphatase activity
FO269_RS14975	COG0583	DNA-binding transcription factor activity
FO269_RS14980	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
FO269_RS14985	COG1882	Formate acetyltransferase
FO269_RS14990	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FO269_RS14995	COG0187	DNA topoisomerase II activity
FO269_RS15010	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
FO269_RS15035	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FO269_RS15045	COG0758	DNA mediated transformation
FO269_RS15090	COG3409	Peptidoglycan-binding domain 1 protein
FO269_RS15090	COG0793	Belongs to the peptidase S41A family
FO269_RS15100	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FO269_RS15110	COG2755	lipolytic protein G-D-S-L family
FO269_RS15115	COG1307	EDD domain protein, DegV family
FO269_RS15120	COG1272	protein, Hemolysin III
FO269_RS15135	COG0488	(ABC) transporter
FO269_RS15150	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FO269_RS15155	COG0457	Tetratricopeptide repeat
FO269_RS15170	COG0539	negative regulation of cytoplasmic translation
FO269_RS15185	COG0514	ATP-dependent DNA helicase (RecQ)
FO269_RS15200	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
FO269_RS15205	COG1187	pseudouridine synthase activity
FO269_RS15210	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
FO269_RS15215	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
FO269_RS15220	COG0456	acetyltransferase
FO269_RS15230	COG2996	Protein conserved in bacteria
FO269_RS15250	COG0587	DNA-directed DNA polymerase activity
FO269_RS15265	COG0737	Belongs to the 5'-nucleotidase family
FO269_RS15280	COG0542	response to heat
FO269_RS15295	COG0300	oxidoreductase activity
FO269_RS15305	COG2755	lipolytic protein G-D-S-L family
FO269_RS15305	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
FO269_RS15315	COG1349	DNA-binding transcription factor activity
FO269_RS15320	COG1105	Belongs to the carbohydrate kinase PfkB family
FO269_RS15325	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FO269_RS15325	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FO269_RS15325	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FO269_RS15335	COG1126	abc transporter atp-binding protein
FO269_RS15340	COG0765	amino acid transport
FO269_RS15365	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
FO269_RS15375	COG1132	(ABC) transporter
FO269_RS15390	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
FO269_RS15440	COG1466	dna polymerase III delta subunit
FO269_RS15445	COG0658	competence protein
FO269_RS15445	COG2333	competence protein COMEC
FO269_RS15455	COG3480	Lon protease (S16) C-terminal proteolytic domain
FO269_RS15465	COG0742	ribosomal rna small subunit methyltransferase
FO269_RS15470	COG4471	UPF0298 protein
FO269_RS15475	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
FO269_RS15480	COG0772	Belongs to the SEDS family
FO269_RS15485	COG1217	gtp-binding protein TYPA
FO269_RS15490	COG0483	inositol monophosphate 1-phosphatase activity
FO269_RS15560	COG1597	lipid kinase activity
FO269_RS15570	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FO269_RS15615	COG1104	cysteine desulfurase activity
FO269_RS15630	COG0494	nUDIX hydrolase
FO269_RS15640	COG3853	Toxic anion resistance protein (TelA)
FO269_RS15645	COG2814	Major facilitator Superfamily
FO269_RS15655	COG1278	Cold shock
FO269_RS15665	COG3599	regulation of cell shape
FO269_RS15685	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
FO269_RS15715	COG0768	penicillin binding
FO269_RS15730	COG2001	Belongs to the MraZ family
FO269_RS15750	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FO269_RS15755	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FO269_RS15765	COG0765	amino acid transport
FO269_RS15770	COG2894	cell division
FO269_RS15775	COG0850	regulation of cytokinetic process
FO269_RS15785	COG1792	Involved in formation and maintenance of cell shape
FO269_RS15790	COG1077	Cell shape determining protein MreB Mrl
FO269_RS15795	COG2003	Belongs to the UPF0758 family
FO269_RS15810	COG0525	valine-tRNA ligase activity
FO269_RS15815	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
FO269_RS15830	COG1104	cysteine desulfurase activity
FO269_RS15900	COG1132	(ABC) transporter