locus-tag	class	description
LacP0625_RS00010	COG0592	DNA-directed DNA polymerase activity
LacP0625_RS00015	COG2501	S4 domain
LacP0625_RS00025	COG0187	DNA topoisomerase II activity
LacP0625_RS00035	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
LacP0625_RS00050	COG0629	single-stranded DNA binding
LacP0625_RS00060	COG1271	oxidase subunit
LacP0625_RS00065	COG1294	oxidase, subunit
LacP0625_RS00125	COG0561	phosphatase activity
LacP0625_RS00285	COG2814	Major facilitator Superfamily
LacP0625_RS00295	COG2409	Drug exporters of the RND superfamily
LacP0625_RS00295	COG1033	growth of symbiont in host cell
LacP0625_RS00300	COG1309	transcriptional regulator
LacP0625_RS00315	COG1732	Glycine betaine
LacP0625_RS00350	COG2217	Heavy metal translocating P-type atpase
LacP0625_RS00360	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
LacP0625_RS00365	COG0159	tryptophan synthase activity
LacP0625_RS00395	COG2814	Major facilitator Superfamily
LacP0625_RS00430	COG1131	(ABC) transporter
LacP0625_RS00445	COG3409	Peptidoglycan-binding domain 1 protein
LacP0625_RS00455	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
LacP0625_RS00475	COG0019	diaminopimelate decarboxylase activity
LacP0625_RS00480	COG0527	aspartate kinase activity
LacP0625_RS00490	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
LacP0625_RS00500	COG1051	belongs to the nudix hydrolase family
LacP0625_RS00545	COG0438	transferase activity, transferring glycosyl groups
LacP0625_RS00590	COG0305	Participates in initiation and elongation during chromosome replication
LacP0625_RS00610	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
LacP0625_RS00615	COG1737	Transcriptional regulator
LacP0625_RS00620	COG1309	transcriptional regulator
LacP0625_RS00625	COG0577	efflux transmembrane transporter activity
LacP0625_RS00625	COG1136	(ABC) transporter
LacP0625_RS00645	COG2217	Heavy metal translocating P-type atpase
LacP0625_RS00650	COG0640	Transcriptional regulator
LacP0625_RS00655	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
LacP0625_RS00660	COG0583	DNA-binding transcription factor activity
LacP0625_RS00675	COG3620	sequence-specific DNA binding
LacP0625_RS00685	COG1131	(ABC) transporter
LacP0625_RS00695	COG1328	CTP reductase activity
LacP0625_RS00760	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
LacP0625_RS00795	COG2252	PERMEase
LacP0625_RS00805	COG0346	lactoylglutathione lyase activity
LacP0625_RS00865	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
LacP0625_RS00905	COG1131	(ABC) transporter
LacP0625_RS00915	COG1511	domain protein
LacP0625_RS00925	COG0477	Major facilitator Superfamily
LacP0625_RS00935	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
LacP0625_RS00940	COG4166	transmembrane transport
LacP0625_RS00960	COG1131	(ABC) transporter
LacP0625_RS00980	COG1132	(ABC) transporter
LacP0625_RS00985	COG1396	sequence-specific DNA binding
LacP0625_RS00995	COG0446	pyridine nucleotide-disulphide oxidoreductase
LacP0625_RS01035	COG0716	FMN binding
LacP0625_RS01060	COG2261	transglycosylase associated protein
LacP0625_RS01075	COG1302	Protein conserved in bacteria
LacP0625_RS01105	COG3442	glutamine amidotransferase
LacP0625_RS01125	COG1192	Involved in chromosome partitioning
LacP0625_RS01130	COG1475	DNA binding
LacP0625_RS01135	COG4481	Protein conserved in bacteria
LacP0625_RS01140	COG0012	GTP binding
LacP0625_RS01150	COG0516	GMP reductase activity
LacP0625_RS01150	COG0517	IMP dehydrogenase activity
LacP0625_RS01170	COG1686	Belongs to the peptidase S11 family
LacP0625_RS01175	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
LacP0625_RS01185	COG1794	racemase activity, acting on amino acids and derivatives
LacP0625_RS01190	COG0656	L-ascorbic acid biosynthetic process
LacP0625_RS01195	COG1737	Transcriptional regulator
LacP0625_RS01200	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
LacP0625_RS01210	COG2610	gluconate transmembrane transporter activity
LacP0625_RS01230	COG0463	Glycosyl transferase, family 2
LacP0625_RS01245	COG2244	polysaccharide biosynthetic process
LacP0625_RS01265	COG1121	(ABC) transporter
LacP0625_RS01280	COG2084	Dehydrogenase
LacP0625_RS01285	COG1164	Oligoendopeptidase f
LacP0625_RS01290	COG1316	TRANSCRIPTIONal
LacP0625_RS01295	COG1114	Component of the transport system for branched-chain amino acids
LacP0625_RS01310	COG1216	Glycosyl transferase, family 2
LacP0625_RS01335	COG0488	(ABC) transporter
LacP0625_RS01360	COG3118	belongs to the thioredoxin family
LacP0625_RS01375	COG0683	leucine binding
LacP0625_RS01405	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
LacP0625_RS01415	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
LacP0625_RS01420	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
LacP0625_RS01445	COG2723	6-phospho-beta-galactosidase activity
LacP0625_RS01450	COG0446	pyridine nucleotide-disulphide oxidoreductase
LacP0625_RS01470	COG2182	Extracellular solute-binding protein
LacP0625_RS01480	COG3583	domain protein
LacP0625_RS01480	COG3064	Membrane
LacP0625_RS01480	COG3525	Glycosyl hydrolase, family 20, catalytic domain
LacP0625_RS01485	COG1482	cell wall glycoprotein biosynthetic process
LacP0625_RS01490	COG2188	Transcriptional regulator
LacP0625_RS01495	COG2222	sugar isomerase
LacP0625_RS01500	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
LacP0625_RS01510	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LacP0625_RS01515	COG3715	PTS system
LacP0625_RS01520	COG3716	PTS system mannose fructose sorbose family IID component
LacP0625_RS01525	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
LacP0625_RS01525	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LacP0625_RS01535	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
LacP0625_RS01540	COG0006	proline dipeptidase activity
LacP0625_RS01545	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
LacP0625_RS01550	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
LacP0625_RS01555	COG1447	Phosphotransferase system cellobiose-specific component IIA
LacP0625_RS01560	COG1363	Peptidase, m42
LacP0625_RS01570	COG2195	Cleaves the N-terminal amino acid of tripeptides
LacP0625_RS01575	COG4166	transmembrane transport
LacP0625_RS01600	COG1129	ABC transporter
LacP0625_RS01610	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
LacP0625_RS01630	COG0351	phosphomethylpyrimidine kinase
LacP0625_RS01635	COG0531	amino acid
LacP0625_RS01645	COG1609	Transcriptional regulator
LacP0625_RS01660	COG1172	Belongs to the binding-protein-dependent transport system permease family
LacP0625_RS01665	COG1879	ABC-type sugar transport system periplasmic component
LacP0625_RS01680	COG0768	penicillin binding
LacP0625_RS01685	COG2814	Major facilitator Superfamily
LacP0625_RS01720	COG1053	succinate dehydrogenase
LacP0625_RS01780	COG2267	carboxylic ester hydrolase activity
LacP0625_RS01835	COG1609	Transcriptional regulator
LacP0625_RS01845	COG3716	PTS system mannose fructose sorbose family IID component
LacP0625_RS01855	COG1262	PFAM Formylglycine-generating sulfatase enzyme
LacP0625_RS01865	COG0641	radical SAM
LacP0625_RS01875	COG3069	C4-dicarboxylate transmembrane transporter activity
LacP0625_RS01885	COG2188	Transcriptional regulator
LacP0625_RS01895	COG3716	PTS system mannose fructose sorbose family IID component
LacP0625_RS01900	COG3715	PTS system
LacP0625_RS01905	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LacP0625_RS01915	COG3933	PFAM sigma-54 factor interaction domain-containing protein
LacP0625_RS01915	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
LacP0625_RS01920	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
LacP0625_RS01925	COG3711	transcriptional antiterminator
LacP0625_RS01940	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
LacP0625_RS01940	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LacP0625_RS01940	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LacP0625_RS01945	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LacP0625_RS01950	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LacP0625_RS01950	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LacP0625_RS01950	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
LacP0625_RS01970	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LacP0625_RS01970	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
LacP0625_RS01970	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LacP0625_RS01975	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LacP0625_RS01975	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LacP0625_RS01980	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
LacP0625_RS01995	COG0191	fructose-bisphosphate aldolase activity
LacP0625_RS02000	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
LacP0625_RS02000	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LacP0625_RS02000	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LacP0625_RS02005	COG1028	Short-chain dehydrogenase reductase Sdr
LacP0625_RS02015	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LacP0625_RS02015	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
LacP0625_RS02020	COG3715	PTS system
LacP0625_RS02025	COG3716	PTS system mannose fructose sorbose family IID component
LacP0625_RS02030	COG0246	Mannitol dehydrogenase
LacP0625_RS02035	COG1461	Dihydroxyacetone kinase
LacP0625_RS02040	COG2376	Dihydroxyacetone kinase
LacP0625_RS02045	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
LacP0625_RS02050	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
LacP0625_RS02055	COG1609	Transcriptional regulator
LacP0625_RS02065	COG2390	Transcriptional regulator
LacP0625_RS02075	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
LacP0625_RS02080	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LacP0625_RS02085	COG3715	PTS system
LacP0625_RS02090	COG3716	PTS system mannose fructose sorbose family IID component
LacP0625_RS02095	COG0191	fructose-bisphosphate aldolase activity
LacP0625_RS02115	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
LacP0625_RS02115	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LacP0625_RS02125	COG3716	PTS system mannose fructose sorbose family IID component
LacP0625_RS02160	COG1122	ATPase activity
LacP0625_RS02170	COG3250	beta-galactosidase activity
LacP0625_RS02175	COG0531	amino acid
LacP0625_RS02180	COG0833	amino acid
LacP0625_RS02185	COG2207	Transcriptional regulator
LacP0625_RS02230	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
LacP0625_RS02235	COG1349	DNA-binding transcription factor activity
LacP0625_RS02240	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
LacP0625_RS02245	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
LacP0625_RS02250	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
LacP0625_RS02250	COG2213	PTS system mannitol-specific
LacP0625_RS02265	COG1126	abc transporter atp-binding protein
LacP0625_RS02270	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LacP0625_RS02275	COG0765	amino acid transport
LacP0625_RS02280	COG0765	amino acid transport
LacP0625_RS02285	COG0477	Major facilitator Superfamily
LacP0625_RS02330	COG0446	pyridine nucleotide-disulphide oxidoreductase
LacP0625_RS02335	COG0561	phosphatase activity
LacP0625_RS02345	COG1609	Transcriptional regulator
LacP0625_RS02350	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LacP0625_RS02360	COG3716	PTS system mannose fructose sorbose family IID component
LacP0625_RS02375	COG0366	Alpha amylase catalytic
LacP0625_RS02385	COG1132	(ABC) transporter
LacP0625_RS02405	COG2271	Major facilitator Superfamily
LacP0625_RS02410	COG1473	amidohydrolase
LacP0625_RS02420	COG1464	Belongs to the NlpA lipoprotein family
LacP0625_RS02445	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
LacP0625_RS02450	COG1461	Dihydroxyacetone kinase
LacP0625_RS02455	COG2376	Dihydroxyacetone kinase
LacP0625_RS02475	COG2814	Major facilitator Superfamily
LacP0625_RS02495	COG0028	Belongs to the TPP enzyme family
LacP0625_RS02510	COG2226	methyltransferase
LacP0625_RS02515	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
LacP0625_RS02520	COG0174	glutamine synthetase
LacP0625_RS02535	COG0789	Transcriptional regulator
LacP0625_RS02540	COG0656	L-ascorbic acid biosynthetic process
LacP0625_RS02550	COG1733	regulation of RNA biosynthetic process
LacP0625_RS02560	COG2723	6-phospho-beta-galactosidase activity
LacP0625_RS02575	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
LacP0625_RS02585	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
LacP0625_RS02610	COG1131	(ABC) transporter
LacP0625_RS02630	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
LacP0625_RS02665	COG0308	aminopeptidase N
LacP0625_RS02670	COG0531	amino acid
LacP0625_RS02690	COG1028	Short-chain dehydrogenase reductase Sdr
LacP0625_RS02700	COG2271	Major facilitator Superfamily
LacP0625_RS02705	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
LacP0625_RS02710	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
LacP0625_RS02715	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
LacP0625_RS02765	COG1396	sequence-specific DNA binding
LacP0625_RS02885	COG2826	transposase and inactivated derivatives, IS30 family
LacP0625_RS02915	COG2801	Transposase and inactivated derivatives
LacP0625_RS03045	COG3547	Transposase (IS116 IS110 IS902 family)
LacP0625_RS03050	COG3464	Transposase
LacP0625_RS03105	COG2217	Heavy metal translocating P-type atpase
LacP0625_RS03135	COG0463	Glycosyl transferase, family 2
LacP0625_RS03145	COG0586	Pfam SNARE associated Golgi protein
LacP0625_RS03150	COG5002	protein histidine kinase activity
LacP0625_RS03155	COG0745	RESPONSE REGULATOR receiver
LacP0625_RS03175	COG1131	(ABC) transporter
LacP0625_RS03185	COG1309	transcriptional regulator
LacP0625_RS03215	COG0783	Belongs to the Dps family
LacP0625_RS03225	COG2801	Transposase and inactivated derivatives
LacP0625_RS03250	COG1053	succinate dehydrogenase
LacP0625_RS03250	COG3976	FMN-binding domain protein
LacP0625_RS03250	COG0431	NADPH-dependent FMN reductase
LacP0625_RS03290	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
LacP0625_RS03300	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
LacP0625_RS03345	COG1131	(ABC) transporter
LacP0625_RS03355	COG1309	transcriptional regulator
LacP0625_RS03370	COG4619	ABC transporter
LacP0625_RS03375	COG0390	transport system, permease component
LacP0625_RS03400	COG1174	glycine betaine transport
LacP0625_RS03410	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LacP0625_RS03425	COG0626	cystathionine gamma-synthase activity
LacP0625_RS03430	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LacP0625_RS03435	COG0765	amino acid transport
LacP0625_RS03445	COG1114	Component of the transport system for branched-chain amino acids
LacP0625_RS03490	COG0697	spore germination
LacP0625_RS03500	COG1131	(ABC) transporter
LacP0625_RS03515	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
LacP0625_RS03520	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
LacP0625_RS03525	COG1132	(ABC) transporter
LacP0625_RS03530	COG1132	(ABC) transporter
LacP0625_RS03535	COG2223	nitrite transmembrane transporter activity
LacP0625_RS03540	COG2188	Transcriptional regulator
LacP0625_RS03545	COG0366	Alpha amylase catalytic
LacP0625_RS03550	COG2190	(PTS) system
LacP0625_RS03550	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LacP0625_RS03550	COG1263	PTS System
LacP0625_RS03560	COG0531	amino acid
LacP0625_RS03565	COG0039	L-malate dehydrogenase activity
LacP0625_RS03570	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
LacP0625_RS03575	COG1278	Cold shock
LacP0625_RS03590	COG0488	(ABC) transporter
LacP0625_RS03595	COG0702	epimerase
LacP0625_RS03600	COG0656	L-ascorbic acid biosynthetic process
LacP0625_RS03605	COG1113	amino acid transport
LacP0625_RS03615	COG0025	NhaP-type Na H and K H
LacP0625_RS03635	COG1131	(ABC) transporter
LacP0625_RS03655	COG0604	alcohol dehydrogenase
LacP0625_RS03660	COG0004	ammonium transporteR
LacP0625_RS03670	COG1285	pathogenesis
LacP0625_RS03690	COG1131	(ABC) transporter
LacP0625_RS03700	COG0488	(ABC) transporter
LacP0625_RS03705	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
LacP0625_RS03710	COG1573	uracil-dna glycosylase
LacP0625_RS03715	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
LacP0625_RS03725	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
LacP0625_RS03730	COG1215	transferase activity, transferring glycosyl groups
LacP0625_RS03735	COG3711	transcriptional antiterminator
LacP0625_RS03740	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
LacP0625_RS03740	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
LacP0625_RS03750	COG1447	Phosphotransferase system cellobiose-specific component IIA
LacP0625_RS03760	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
LacP0625_RS03770	COG1609	Transcriptional regulator
LacP0625_RS03775	COG2017	converts alpha-aldose to the beta-anomer
LacP0625_RS03830	COG3684	Belongs to the aldolase LacD family
LacP0625_RS03845	COG1349	DNA-binding transcription factor activity
LacP0625_RS03860	COG0419	ATPase involved in DNA repair
LacP0625_RS03875	COG1194	a g-specific adenine glycosylase
LacP0625_RS03885	COG2249	NAD(P)H dehydrogenase (quinone) activity
LacP0625_RS03905	COG0351	phosphomethylpyrimidine kinase
LacP0625_RS03920	COG2910	NAD(P)H-binding
LacP0625_RS03925	COG1472	Belongs to the glycosyl hydrolase 3 family
LacP0625_RS03940	COG4120	Belongs to the binding-protein-dependent transport system permease family
LacP0625_RS03950	COG0604	alcohol dehydrogenase
LacP0625_RS03960	COG0463	Glycosyl transferase, family 2
LacP0625_RS03965	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
LacP0625_RS03975	COG0745	RESPONSE REGULATOR receiver
LacP0625_RS03980	COG5002	protein histidine kinase activity
LacP0625_RS04015	COG0778	Nitroreductase
LacP0625_RS04020	COG1304	FMN binding
LacP0625_RS04055	COG0604	alcohol dehydrogenase
LacP0625_RS04070	COG0628	permease
LacP0625_RS04095	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
LacP0625_RS04105	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
LacP0625_RS04110	COG3189	MarR family transcriptional regulator
LacP0625_RS04120	COG3464	Transposase
LacP0625_RS04145	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
LacP0625_RS04170	COG1028	Short-chain dehydrogenase reductase Sdr
LacP0625_RS04175	COG0105	UTP biosynthetic process
LacP0625_RS04180	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
LacP0625_RS04185	COG2267	carboxylic ester hydrolase activity
LacP0625_RS04215	COG2267	carboxylic ester hydrolase activity
LacP0625_RS04250	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
LacP0625_RS04275	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
LacP0625_RS04280	COG0343	queuine tRNA-ribosyltransferase activity
LacP0625_RS04285	COG1862	Preprotein translocase
LacP0625_RS04290	COG1454	alcohol dehydrogenase
LacP0625_RS04290	COG1012	belongs to the aldehyde dehydrogenase family
LacP0625_RS04300	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
LacP0625_RS04305	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
LacP0625_RS04310	COG4109	DRTGG domain
LacP0625_RS04315	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
LacP0625_RS04320	COG0513	Belongs to the DEAD box helicase family
LacP0625_RS04365	COG3118	belongs to the thioredoxin family
LacP0625_RS04380	COG1696	Membrane protein involved in D-alanine export
LacP0625_RS04390	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
LacP0625_RS04395	COG1719	4-vinyl reductase, 4VR
LacP0625_RS04400	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
LacP0625_RS04410	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
LacP0625_RS04425	COG0668	transmembrane transport
LacP0625_RS04440	COG1827	regulation of RNA biosynthetic process
LacP0625_RS04445	COG0006	proline dipeptidase activity
LacP0625_RS04450	COG1609	Transcriptional regulator
LacP0625_RS04455	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
LacP0625_RS04460	COG1011	Hydrolase
LacP0625_RS04500	COG0737	Belongs to the 5'-nucleotidase family
LacP0625_RS04505	COG4470	Protein conserved in bacteria
LacP0625_RS04510	COG0647	UMP catabolic process
LacP0625_RS04520	COG0586	Pfam SNARE associated Golgi protein
LacP0625_RS04525	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
LacP0625_RS04540	COG1098	S1 RNA binding domain
LacP0625_RS04690	COG0531	amino acid
LacP0625_RS04695	COG0438	transferase activity, transferring glycosyl groups
LacP0625_RS04700	COG0438	transferase activity, transferring glycosyl groups
LacP0625_RS04715	COG0436	Aminotransferase
LacP0625_RS04725	COG1368	sulfuric ester hydrolase activity
LacP0625_RS04730	COG0735	belongs to the Fur family
LacP0625_RS04775	COG0477	Major facilitator Superfamily
LacP0625_RS04785	COG2814	Major facilitator Superfamily
LacP0625_RS04795	COG0671	phosphoesterase, PA-phosphatase related
LacP0625_RS04805	COG2244	polysaccharide biosynthetic process
LacP0625_RS04810	COG1187	pseudouridine synthase activity
LacP0625_RS04820	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
LacP0625_RS04840	COG0438	transferase activity, transferring glycosyl groups
LacP0625_RS04845	COG0386	Belongs to the glutathione peroxidase family
LacP0625_RS04850	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
LacP0625_RS04860	COG3830	Belongs to the UPF0237 family
LacP0625_RS04885	COG2357	RelA SpoT domain protein
LacP0625_RS04895	COG0564	pseudouridine synthase activity
LacP0625_RS04905	COG3142	Participates in the control of copper homeostasis
LacP0625_RS04915	COG2706	6-phosphogluconolactonase activity
LacP0625_RS04925	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
LacP0625_RS04940	COG2226	methyltransferase
LacP0625_RS04945	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
LacP0625_RS04955	COG1674	ftsk spoiiie
LacP0625_RS04960	COG0612	Peptidase, M16
LacP0625_RS04965	COG0612	Peptidase, M16
LacP0625_RS04970	COG1028	Short-chain dehydrogenase reductase Sdr
LacP0625_RS04975	COG1426	Protein conserved in bacteria
LacP0625_RS04980	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
LacP0625_RS04990	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
LacP0625_RS05000	COG1739	Uncharacterized protein family UPF0029
LacP0625_RS05005	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
LacP0625_RS05030	COG2884	Cell division ATP-binding protein ftsE
LacP0625_RS05035	COG2177	Part of the ABC transporter FtsEX involved in
LacP0625_RS05045	COG0745	RESPONSE REGULATOR receiver
LacP0625_RS05050	COG5002	protein histidine kinase activity
LacP0625_RS05060	COG0573	inorganic phosphate transmembrane transporter activity
LacP0625_RS05065	COG0581	inorganic phosphate transmembrane transporter activity
LacP0625_RS05070	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
LacP0625_RS05075	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
LacP0625_RS05080	COG0704	Plays a role in the regulation of phosphate uptake
LacP0625_RS05095	COG1950	PFAM Membrane protein of
LacP0625_RS05105	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
LacP0625_RS05115	COG0492	ferredoxin-NADP+ reductase activity
LacP0625_RS05120	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
LacP0625_RS05125	COG0745	RESPONSE REGULATOR receiver
LacP0625_RS05130	COG2205	protein histidine kinase activity
LacP0625_RS05135	COG1136	(ABC) transporter
LacP0625_RS05155	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
LacP0625_RS05170	COG0391	Required for morphogenesis under gluconeogenic growth conditions
LacP0625_RS05180	COG1846	Transcriptional regulator
LacP0625_RS05195	COG2390	Transcriptional regulator
LacP0625_RS05235	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
LacP0625_RS05245	COG0557	exoribonuclease II activity
LacP0625_RS05255	COG1609	Transcriptional regulator
LacP0625_RS05260	COG0366	Alpha amylase catalytic
LacP0625_RS05275	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
LacP0625_RS05305	COG0395	ABC-type sugar transport system, permease component
LacP0625_RS05310	COG1175	transmembrane transport
LacP0625_RS05330	COG0561	phosphatase activity
LacP0625_RS05340	COG0280	phosphate acetyltransferase
LacP0625_RS05345	COG0802	atpase or kinase
LacP0625_RS05350	COG4152	abc transporter atp-binding protein
LacP0625_RS05355	COG1668	transmembrane transport
LacP0625_RS05365	COG0708	Exodeoxyribonuclease III
LacP0625_RS05380	COG3800	Transcriptional regulator
LacP0625_RS05380	COG1396	sequence-specific DNA binding
LacP0625_RS05390	COG1176	ABC-type spermidine putrescine transport system, permease component I
LacP0625_RS05395	COG1177	transmembrane transport
LacP0625_RS05400	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
LacP0625_RS05415	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
LacP0625_RS05420	COG1309	transcriptional regulator
LacP0625_RS05450	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
LacP0625_RS05475	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
LacP0625_RS05480	COG1459	type II secretion system
LacP0625_RS05510	COG0827	DNA restriction-modification system
LacP0625_RS05520	COG1113	amino acid transport
LacP0625_RS05625	COG4695	Portal protein
LacP0625_RS05650	COG2261	transglycosylase associated protein
LacP0625_RS05665	COG0745	RESPONSE REGULATOR receiver
LacP0625_RS05670	COG3850	Histidine kinase
LacP0625_RS05670	COG5002	protein histidine kinase activity
LacP0625_RS05700	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
LacP0625_RS05760	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
LacP0625_RS05765	COG2814	Major facilitator Superfamily
LacP0625_RS05770	COG0561	phosphatase activity
LacP0625_RS05775	COG2326	polyphosphate kinase activity
LacP0625_RS05780	COG3590	peptidase
LacP0625_RS05785	COG2814	Major facilitator Superfamily
LacP0625_RS05795	COG1307	EDD domain protein, DegV family
LacP0625_RS05825	COG0673	inositol 2-dehydrogenase activity
LacP0625_RS05835	COG1447	Phosphotransferase system cellobiose-specific component IIA
LacP0625_RS05855	COG0514	ATP-dependent DNA helicase (RecQ)
LacP0625_RS05860	COG2309	aminopeptidase activity
LacP0625_RS05875	COG1295	ribonuclease BN
LacP0625_RS05880	COG0716	FMN binding
LacP0625_RS05885	COG0024	Methionine aminopeptidase
LacP0625_RS05890	COG0463	Glycosyl transferase, family 2
LacP0625_RS05910	COG1210	Utp--glucose-1-phosphate uridylyltransferase
LacP0625_RS05940	COG1263	PTS System
LacP0625_RS05940	COG2190	(PTS) system
LacP0625_RS05940	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LacP0625_RS05945	COG3711	transcriptional antiterminator
LacP0625_RS05950	COG4485	Bacterial membrane protein, YfhO
LacP0625_RS05960	COG0463	Glycosyl transferase, family 2
LacP0625_RS05970	COG4129	membrane
LacP0625_RS05980	COG1278	Cold shock
LacP0625_RS05990	COG1705	Flagellar rod assembly protein muramidase FlgJ
LacP0625_RS06005	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
LacP0625_RS06010	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
LacP0625_RS06025	COG1368	sulfuric ester hydrolase activity
LacP0625_RS06035	COG4975	Glucose uptake
LacP0625_RS06045	COG0582	viral genome integration into host DNA
LacP0625_RS06130	COG3723	Recombinational DNA repair protein, rece pathway
LacP0625_RS06380	COG0590	tRNA wobble adenosine to inosine editing
LacP0625_RS06410	COG3548	integral membrane protein
LacP0625_RS06465	COG2514	catechol 2,3-dioxygenase activity
LacP0625_RS06475	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
LacP0625_RS06480	COG1435	thymidine kinase activity
LacP0625_RS06490	COG2890	protein-(glutamine-N5) methyltransferase activity
LacP0625_RS06495	COG0009	L-threonylcarbamoyladenylate synthase
LacP0625_RS06510	COG0356	it plays a direct role in the translocation of protons across the membrane
LacP0625_RS06555	COG1077	Cell shape determining protein MreB Mrl
LacP0625_RS06575	COG0772	Belongs to the SEDS family
LacP0625_RS06580	COG0509	glycine decarboxylation via glycine cleavage system
LacP0625_RS06585	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
LacP0625_RS06590	COG1464	Belongs to the NlpA lipoprotein family
LacP0625_RS06595	COG1464	Belongs to the NlpA lipoprotein family
LacP0625_RS06605	COG2011	ABC-type metal ion transport system permease component
LacP0625_RS06615	COG0719	Fe-S assembly protein
LacP0625_RS06620	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
LacP0625_RS06625	COG0822	iron-sulfur transferase activity
LacP0625_RS06630	COG0719	Fe-S assembly protein
LacP0625_RS06660	COG0589	response to stress
LacP0625_RS06670	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
LacP0625_RS06675	COG0189	ligase activity
LacP0625_RS06675	COG2918	glutathione biosynthetic process
LacP0625_RS06680	COG5506	Protein of unknown function (DUF1694)
LacP0625_RS06690	COG1760	l-serine dehydratase
LacP0625_RS06695	COG1760	l-serine dehydratase
LacP0625_RS06705	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
LacP0625_RS06710	COG1028	Short-chain dehydrogenase reductase Sdr
LacP0625_RS06720	COG1428	Deoxynucleoside kinase
LacP0625_RS06730	COG4166	transmembrane transport
LacP0625_RS06735	COG2205	protein histidine kinase activity
LacP0625_RS06740	COG0745	RESPONSE REGULATOR receiver
LacP0625_RS06790	COG0454	-acetyltransferase
LacP0625_RS06800	COG2972	Histidine kinase
LacP0625_RS06805	COG2207	Transcriptional regulator
LacP0625_RS06805	COG4753	response regulator
LacP0625_RS06810	COG1840	ABC-type Fe3 transport system, periplasmic component
LacP0625_RS06815	COG3842	ATPase activity
LacP0625_RS06820	COG1178	ABC-type Fe3 transport system permease component
LacP0625_RS06825	COG1307	EDD domain protein, DegV family
LacP0625_RS06830	COG2197	response regulator
LacP0625_RS06835	COG4585	Histidine kinase
LacP0625_RS06840	COG0842	Transport permease protein
LacP0625_RS06845	COG1131	(ABC) transporter
LacP0625_RS06895	COG2183	response to ionizing radiation
LacP0625_RS06920	COG4372	Transposase
LacP0625_RS06950	COG3620	sequence-specific DNA binding
LacP0625_RS06960	COG1956	GAF domain-containing protein
LacP0625_RS06965	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
LacP0625_RS06970	COG1104	cysteine desulfurase activity
LacP0625_RS06980	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
LacP0625_RS06985	COG0525	valine-tRNA ligase activity
LacP0625_RS07000	COG2003	Belongs to the UPF0758 family
LacP0625_RS07005	COG1077	Cell shape determining protein MreB Mrl
LacP0625_RS07010	COG1792	Involved in formation and maintenance of cell shape
LacP0625_RS07020	COG0850	regulation of cytokinetic process
LacP0625_RS07025	COG2894	cell division
LacP0625_RS07030	COG0765	amino acid transport
LacP0625_RS07040	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LacP0625_RS07045	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LacP0625_RS07060	COG2001	Belongs to the MraZ family
LacP0625_RS07075	COG0768	penicillin binding
LacP0625_RS07105	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
LacP0625_RS07125	COG3599	regulation of cell shape
LacP0625_RS07135	COG1278	Cold shock
LacP0625_RS07145	COG2814	Major facilitator Superfamily
LacP0625_RS07150	COG3853	Toxic anion resistance protein (TelA)
LacP0625_RS07160	COG0494	nUDIX hydrolase
LacP0625_RS07175	COG1104	cysteine desulfurase activity
LacP0625_RS07205	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
LacP0625_RS07215	COG1597	lipid kinase activity
LacP0625_RS07280	COG0483	inositol monophosphate 1-phosphatase activity
LacP0625_RS07285	COG1217	gtp-binding protein TYPA
LacP0625_RS07290	COG0772	Belongs to the SEDS family
LacP0625_RS07295	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
LacP0625_RS07300	COG4471	UPF0298 protein
LacP0625_RS07305	COG0742	ribosomal rna small subunit methyltransferase
LacP0625_RS07315	COG3480	Lon protease (S16) C-terminal proteolytic domain
LacP0625_RS07325	COG0658	competence protein
LacP0625_RS07325	COG2333	competence protein COMEC
LacP0625_RS07330	COG1466	dna polymerase III delta subunit
LacP0625_RS07365	COG1132	(ABC) transporter
LacP0625_RS07375	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
LacP0625_RS07395	COG0765	amino acid transport
LacP0625_RS07400	COG1126	abc transporter atp-binding protein
LacP0625_RS07410	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LacP0625_RS07410	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
LacP0625_RS07410	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LacP0625_RS07415	COG1105	Belongs to the carbohydrate kinase PfkB family
LacP0625_RS07420	COG1349	DNA-binding transcription factor activity
LacP0625_RS07430	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
LacP0625_RS07430	COG2755	lipolytic protein G-D-S-L family
LacP0625_RS07440	COG0300	oxidoreductase activity
LacP0625_RS07450	COG0542	response to heat
LacP0625_RS07465	COG0737	Belongs to the 5'-nucleotidase family
LacP0625_RS07480	COG0587	DNA-directed DNA polymerase activity
LacP0625_RS07500	COG2996	Protein conserved in bacteria
LacP0625_RS07510	COG0456	acetyltransferase
LacP0625_RS07515	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
LacP0625_RS07520	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
LacP0625_RS07525	COG1187	pseudouridine synthase activity
LacP0625_RS07530	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
LacP0625_RS07545	COG0514	ATP-dependent DNA helicase (RecQ)
LacP0625_RS07560	COG0539	negative regulation of cytoplasmic translation
LacP0625_RS07575	COG0457	Tetratricopeptide repeat
LacP0625_RS07580	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
LacP0625_RS07595	COG0488	(ABC) transporter
LacP0625_RS07610	COG1272	protein, Hemolysin III
LacP0625_RS07615	COG1307	EDD domain protein, DegV family
LacP0625_RS07620	COG2755	lipolytic protein G-D-S-L family
LacP0625_RS07630	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
LacP0625_RS07640	COG0793	Belongs to the peptidase S41A family
LacP0625_RS07640	COG3409	Peptidoglycan-binding domain 1 protein
LacP0625_RS07660	COG0758	DNA mediated transformation
LacP0625_RS07665	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
LacP0625_RS07685	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
LacP0625_RS07700	COG0187	DNA topoisomerase II activity
LacP0625_RS07705	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
LacP0625_RS07710	COG1882	Formate acetyltransferase
LacP0625_RS07715	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
LacP0625_RS07720	COG0583	DNA-binding transcription factor activity
LacP0625_RS07725	COG1227	inorganic diphosphatase activity
LacP0625_RS07730	COG4974	Belongs to the 'phage' integrase family
LacP0625_RS07740	COG0577	efflux transmembrane transporter activity
LacP0625_RS07745	COG1136	(ABC) transporter
LacP0625_RS07750	COG5002	protein histidine kinase activity
LacP0625_RS07755	COG0745	RESPONSE REGULATOR receiver
LacP0625_RS07775	COG0778	Nitroreductase
LacP0625_RS07780	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
LacP0625_RS07815	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
LacP0625_RS07830	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
LacP0625_RS07835	COG0494	nUDIX hydrolase
LacP0625_RS07840	COG1307	EDD domain protein, DegV family
LacP0625_RS07845	COG1293	RNA-binding protein homologous to eukaryotic snRNP
LacP0625_RS07860	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
LacP0625_RS07865	COG0508	dehydrogenase complex catalyzes the overall conversion of
LacP0625_RS07870	COG0022	dehydrogenase e1 component
LacP0625_RS07875	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
LacP0625_RS07885	COG3426	butyrate kinase activity
LacP0625_RS07890	COG0280	phosphate acetyltransferase
LacP0625_RS07895	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
LacP0625_RS07900	COG0284	orotidine-5'-phosphate decarboxylase activity
LacP0625_RS07915	COG0505	Belongs to the CarA family
LacP0625_RS07920	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
LacP0625_RS07930	COG2233	PERMEase
LacP0625_RS07935	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
LacP0625_RS07940	COG0564	pseudouridine synthase activity
LacP0625_RS07945	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
LacP0625_RS07960	COG0328	RNA-DNA hybrid ribonuclease activity
LacP0625_RS07970	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LacP0625_RS07985	COG1393	Belongs to the ArsC family
LacP0625_RS07990	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LacP0625_RS07995	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LacP0625_RS08000	COG0583	DNA-binding transcription factor activity
LacP0625_RS08005	COG3590	peptidase
LacP0625_RS08010	COG0095	Lipoate-protein ligase
LacP0625_RS08025	COG0116	Belongs to the methyltransferase superfamily
LacP0625_RS08050	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
LacP0625_RS08055	COG2131	deaminase
LacP0625_RS08060	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
LacP0625_RS08075	COG0436	Aminotransferase
LacP0625_RS08085	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
LacP0625_RS08085	COG1199	ATP-dependent helicase activity
LacP0625_RS08120	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
LacP0625_RS08120	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
LacP0625_RS08135	COG2151	metal-sulfur cluster biosynthetic enzyme
LacP0625_RS08140	COG1942	4-Oxalocrotonate Tautomerase
LacP0625_RS08145	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
LacP0625_RS08150	COG2384	SAM-dependent methyltransferase
LacP0625_RS08155	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
LacP0625_RS08160	COG0358	DNA primase activity
LacP0625_RS08270	COG3711	transcriptional antiterminator
LacP0625_RS08270	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
LacP0625_RS08275	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
LacP0625_RS08285	COG2723	6-phospho-beta-galactosidase activity
LacP0625_RS08290	COG1447	Phosphotransferase system cellobiose-specific component IIA
LacP0625_RS08295	COG2723	6-phospho-beta-galactosidase activity
LacP0625_RS08425	COG1381	Involved in DNA repair and RecF pathway recombination
LacP0625_RS08435	COG0295	cytidine deaminase activity
LacP0625_RS08450	COG1702	phosphate starvation-inducible protein PhoH
LacP0625_RS08455	COG1610	YqeY-like protein
LacP0625_RS08470	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
LacP0625_RS08475	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
LacP0625_RS08480	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
LacP0625_RS08510	COG1131	(ABC) transporter
LacP0625_RS08520	COG4991	sh3 domain protein
LacP0625_RS08520	COG3103	Sh3 type 3 domain protein
LacP0625_RS08520	COG0860	N-Acetylmuramoyl-L-alanine amidase
LacP0625_RS08535	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
LacP0625_RS08545	COG1385	rRNA (uridine-N3-)-methyltransferase activity
LacP0625_RS08560	COG2094	Belongs to the DNA glycosylase MPG family
LacP0625_RS08600	COG2249	NAD(P)H dehydrogenase (quinone) activity
LacP0625_RS08620	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
LacP0625_RS08630	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
LacP0625_RS08630	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
LacP0625_RS08660	COG1132	(ABC) transporter
LacP0625_RS08675	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
LacP0625_RS08685	COG0635	Involved in the biosynthesis of porphyrin-containing compound
LacP0625_RS08690	COG0196	riboflavin kinase activity
LacP0625_RS08700	COG0861	Integral membrane protein TerC family
LacP0625_RS08720	COG2740	Nucleic-acid-binding protein implicated in transcription termination
LacP0625_RS08725	COG0195	Participates in both transcription termination and antitermination
LacP0625_RS08745	COG0750	zinc metalloprotease
LacP0625_RS08750	COG4589	Belongs to the CDS family
LacP0625_RS08755	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
LacP0625_RS08785	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
LacP0625_RS08790	COG0204	Acyl-transferase
LacP0625_RS08795	COG0531	amino acid
LacP0625_RS08805	COG1132	(ABC) transporter
LacP0625_RS08810	COG1132	(ABC) transporter
LacP0625_RS08815	COG3763	UPF0154 protein
LacP0625_RS08820	COG4224	UPF0291 protein
LacP0625_RS08845	COG1837	Belongs to the UPF0109 family
LacP0625_RS08855	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
LacP0625_RS08870	COG0552	protein localization to endoplasmic reticulum
LacP0625_RS08875	COG1196	nuclear chromosome segregation
LacP0625_RS08880	COG0571	ribonuclease III activity
LacP0625_RS08885	COG0747	negative chemotaxis
LacP0625_RS08890	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LacP0625_RS08895	COG0601	transmembrane transport
LacP0625_RS08900	COG4608	Belongs to the ABC transporter superfamily
LacP0625_RS08910	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LacP0625_RS08920	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
LacP0625_RS08925	COG1461	Dihydroxyacetone kinase
LacP0625_RS08940	COG1564	THIamine pyrophosphokinase
LacP0625_RS08945	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
LacP0625_RS08950	COG1162	GTPase activity
LacP0625_RS08955	COG2815	serine threonine protein kinase
LacP0625_RS08955	COG0515	serine threonine protein kinase
LacP0625_RS08965	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
LacP0625_RS08965	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
LacP0625_RS08975	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
LacP0625_RS08980	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
LacP0625_RS08990	COG0194	GDP metabolic process
LacP0625_RS09005	COG0497	DNA recombination
LacP0625_RS09010	COG1438	arginine binding
LacP0625_RS09015	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
LacP0625_RS09020	COG0142	geranyltranstransferase activity
LacP0625_RS09025	COG1722	exodeoxyribonuclease VII activity
LacP0625_RS09045	COG1302	Protein conserved in bacteria
LacP0625_RS09050	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
LacP0625_RS09055	COG0006	proline dipeptidase activity
LacP0625_RS09060	COG0211	Belongs to the bacterial ribosomal protein bL27 family
LacP0625_RS09065	COG2868	ribosomal protein
LacP0625_RS09070	COG0261	This protein binds to 23S rRNA in the presence of protein L20
LacP0625_RS09100	COG0789	Transcriptional regulator
LacP0625_RS09105	COG1982	Orn Lys Arg decarboxylase major
LacP0625_RS09110	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
LacP0625_RS09125	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
LacP0625_RS09130	COG1940	carbohydrate kinase activity
LacP0625_RS09140	COG0457	Tetratricopeptide repeat
LacP0625_RS09140	COG0705	Rhomboid family
LacP0625_RS09145	COG0768	penicillin binding
LacP0625_RS09155	COG4841	protein insertion into membrane
LacP0625_RS09160	COG2197	response regulator
LacP0625_RS09175	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
LacP0625_RS09180	COG0572	uridine kinase
LacP0625_RS09185	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
LacP0625_RS09190	COG0072	phenylalanine-tRNA ligase activity
LacP0625_RS09200	COG1733	regulation of RNA biosynthetic process
LacP0625_RS09210	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LacP0625_RS09220	COG0706	membrane insertase activity
LacP0625_RS09225	COG5002	protein histidine kinase activity
LacP0625_RS09230	COG0745	RESPONSE REGULATOR receiver
LacP0625_RS09245	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
LacP0625_RS09265	COG2226	methyltransferase
LacP0625_RS09270	COG0799	negative regulation of ribosome biogenesis
LacP0625_RS09280	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
LacP0625_RS09285	COG1534	Rna-binding protein
LacP0625_RS09290	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
LacP0625_RS09295	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
LacP0625_RS09300	COG0346	lactoylglutathione lyase activity
LacP0625_RS09305	COG0346	lactoylglutathione lyase activity
LacP0625_RS09310	COG0400	carboxylic ester hydrolase activity
LacP0625_RS09335	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
LacP0625_RS09365	COG1484	DNA-dependent DNA replication
LacP0625_RS09370	COG3611	Membrane attachment protein
LacP0625_RS09380	COG0237	dephospho-CoA kinase activity
LacP0625_RS09385	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
LacP0625_RS09390	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
LacP0625_RS09390	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
LacP0625_RS09395	COG0670	Belongs to the BI1 family
LacP0625_RS09405	COG1674	ftsk spoiiie
LacP0625_RS09410	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LacP0625_RS09415	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LacP0625_RS09440	COG1131	(ABC) transporter
LacP0625_RS09445	COG0537	adenosine 5'-monophosphoramidase activity
LacP0625_RS09455	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
LacP0625_RS09470	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
LacP0625_RS09475	COG0564	pseudouridine synthase activity
LacP0625_RS09480	COG1438	arginine binding
LacP0625_RS09485	COG0018	arginyl-trna synthetase
LacP0625_RS09505	COG0167	dihydroorotate dehydrogenase activity
LacP0625_RS09520	COG1393	Belongs to the ArsC family
LacP0625_RS09525	COG1234	tRNA 3'-trailer cleavage
LacP0625_RS09540	COG1136	(ABC) transporter
LacP0625_RS09545	COG0745	RESPONSE REGULATOR receiver
LacP0625_RS09550	COG0642	Histidine kinase
LacP0625_RS09560	COG2217	Heavy metal translocating P-type atpase
LacP0625_RS09565	COG3682	Transcriptional regulator
LacP0625_RS09570	COG0151	Belongs to the GarS family
LacP0625_RS09580	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
LacP0625_RS09585	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
LacP0625_RS09605	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
LacP0625_RS09615	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
LacP0625_RS09620	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
LacP0625_RS09630	COG2814	Major facilitator Superfamily
LacP0625_RS09640	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
LacP0625_RS09650	COG0542	response to heat
LacP0625_RS09665	COG1253	flavin adenine dinucleotide binding
LacP0625_RS09670	COG0628	permease
LacP0625_RS09685	COG3557	Belongs to the UPF0374 family
LacP0625_RS09705	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
LacP0625_RS09715	COG2188	Transcriptional regulator
LacP0625_RS09720	COG2723	6-phospho-beta-galactosidase activity
LacP0625_RS09725	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
LacP0625_RS09735	COG1447	Phosphotransferase system cellobiose-specific component IIA
LacP0625_RS09740	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
LacP0625_RS09745	COG0028	Belongs to the TPP enzyme family
LacP0625_RS09750	COG3425	synthase
LacP0625_RS09760	COG0183	Belongs to the thiolase family
LacP0625_RS09785	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
LacP0625_RS09805	COG3091	SprT-like family
LacP0625_RS09810	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
LacP0625_RS09815	COG4120	Belongs to the binding-protein-dependent transport system permease family
LacP0625_RS09850	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
LacP0625_RS09855	COG2188	Transcriptional regulator
LacP0625_RS09860	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
LacP0625_RS09865	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
LacP0625_RS09870	COG4946	Tricorn protease homolog
LacP0625_RS09870	COG1506	peptidase
LacP0625_RS09870	COG0823	Involved in the tonB-independent uptake of proteins
LacP0625_RS09885	COG3104	oligopeptide transport
LacP0625_RS09890	COG0577	efflux transmembrane transporter activity
LacP0625_RS09890	COG1136	(ABC) transporter
LacP0625_RS10220	COG3561	AntA/AntB antirepressor
LacP0625_RS10330	COG0833	amino acid
LacP0625_RS10340	COG0028	Belongs to the TPP enzyme family
LacP0625_RS10375	COG0564	pseudouridine synthase activity
LacP0625_RS10395	COG3697	Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase
LacP0625_RS10395	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
LacP0625_RS10410	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
LacP0625_RS10410	COG3697	Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase
LacP0625_RS10445	COG0511	ligase activity, forming carbon-carbon bonds
LacP0625_RS10455	COG2851	Citrate transporter
LacP0625_RS10495	COG1131	(ABC) transporter
LacP0625_RS10510	COG2814	Major facilitator Superfamily
LacP0625_RS10530	COG1725	Transcriptional regulator
LacP0625_RS10535	COG1131	(ABC) transporter
LacP0625_RS10560	COG1136	(ABC) transporter
LacP0625_RS10570	COG4608	Belongs to the ABC transporter superfamily
LacP0625_RS10575	COG0444	Belongs to the ABC transporter superfamily
LacP0625_RS10585	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LacP0625_RS10590	COG0601	transmembrane transport
LacP0625_RS10595	COG4166	transmembrane transport
LacP0625_RS10605	COG0640	Transcriptional regulator
LacP0625_RS10615	COG1132	(ABC) transporter
LacP0625_RS10620	COG1132	(ABC) transporter
LacP0625_RS10640	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LacP0625_RS10640	COG5549	protein import
LacP0625_RS10645	COG1349	DNA-binding transcription factor activity
LacP0625_RS10670	COG2815	serine threonine protein kinase
LacP0625_RS10670	COG0515	serine threonine protein kinase
LacP0625_RS10735	COG4690	dipeptidase activity
LacP0625_RS10740	COG1607	acyl-coa hydrolase
LacP0625_RS10745	COG3973	AAA domain
LacP0625_RS10755	COG0569	domain protein
LacP0625_RS10755	COG0475	glutathione-regulated potassium exporter activity
LacP0625_RS10760	COG2267	carboxylic ester hydrolase activity
LacP0625_RS10790	COG1136	(ABC) transporter
LacP0625_RS10795	COG0531	amino acid
LacP0625_RS10805	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
LacP0625_RS10810	COG0726	polysaccharide deacetylase
LacP0625_RS10845	COG1091	dTDP-4-dehydrorhamnose reductase activity
LacP0625_RS10850	COG1088	dTDP-glucose 4,6-dehydratase activity
LacP0625_RS10860	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
LacP0625_RS10870	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
LacP0625_RS10880	COG0765	amino acid transport
LacP0625_RS10885	COG0765	amino acid transport
LacP0625_RS10890	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LacP0625_RS10910	COG0735	belongs to the Fur family
LacP0625_RS10920	COG0194	GDP metabolic process
LacP0625_RS10925	COG0454	-acetyltransferase
LacP0625_RS10925	COG0456	acetyltransferase
LacP0625_RS10935	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
LacP0625_RS10960	COG0058	SHG alpha-glucan phosphorylase activity
LacP0625_RS10970	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
LacP0625_RS10980	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
LacP0625_RS10985	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
LacP0625_RS11000	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
LacP0625_RS11010	COG1393	Belongs to the ArsC family
LacP0625_RS11020	COG4464	protein tyrosine phosphatase activity
LacP0625_RS11025	COG1316	TRANSCRIPTIONal
LacP0625_RS11035	COG1091	dTDP-4-dehydrorhamnose reductase activity
LacP0625_RS11040	COG1088	dTDP-glucose 4,6-dehydratase activity
LacP0625_RS11050	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
LacP0625_RS11055	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
LacP0625_RS11065	COG2244	polysaccharide biosynthetic process
LacP0625_RS11090	COG1442	glycosyl transferase family 8
LacP0625_RS11090	COG1216	Glycosyl transferase, family 2
LacP0625_RS11105	COG0489	protein tyrosine kinase activity
LacP0625_RS11120	COG4708	membrane
LacP0625_RS11125	COG1028	Short-chain dehydrogenase reductase Sdr
LacP0625_RS11145	COG4608	Belongs to the ABC transporter superfamily
LacP0625_RS11150	COG0444	Belongs to the ABC transporter superfamily
LacP0625_RS11155	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LacP0625_RS11160	COG0601	transmembrane transport
LacP0625_RS11165	COG4166	transmembrane transport
LacP0625_RS11170	COG2814	Major facilitator Superfamily
LacP0625_RS11175	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
LacP0625_RS11180	COG1556	Lactate utilization protein
LacP0625_RS11185	COG1139	Iron-sulfur cluster binding protein
LacP0625_RS11200	COG1447	Phosphotransferase system cellobiose-specific component IIA
LacP0625_RS11220	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
LacP0625_RS11255	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LacP0625_RS11305	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LacP0625_RS11305	COG2190	(PTS) system
LacP0625_RS11305	COG1263	PTS System
LacP0625_RS11310	COG0366	Alpha amylase catalytic
LacP0625_RS11315	COG1609	Transcriptional regulator
LacP0625_RS11325	COG0702	epimerase
LacP0625_RS11330	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
LacP0625_RS11345	COG0439	Biotin carboxylase
LacP0625_RS11355	COG0511	ligase activity, forming carbon-carbon bonds
LacP0625_RS11360	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
LacP0625_RS11365	COG1028	Short-chain dehydrogenase reductase Sdr
LacP0625_RS11380	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LacP0625_RS11385	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
LacP0625_RS11395	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
LacP0625_RS11400	COG2267	carboxylic ester hydrolase activity
LacP0625_RS11405	COG1979	alcohol dehydrogenase
LacP0625_RS11435	COG1846	Transcriptional regulator
LacP0625_RS11440	COG1132	(ABC) transporter
LacP0625_RS11445	COG0494	nUDIX hydrolase
LacP0625_RS11450	COG0588	phosphoglycerate mutase activity
LacP0625_RS11470	COG0628	permease
LacP0625_RS11485	COG1597	lipid kinase activity
LacP0625_RS11490	COG0028	Belongs to the TPP enzyme family
LacP0625_RS11535	COG0460	homoserine dehydrogenase
LacP0625_RS11540	COG0527	aspartate kinase activity
LacP0625_RS11545	COG2268	Band 7 protein
LacP0625_RS11560	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LacP0625_RS11565	COG0436	Aminotransferase
LacP0625_RS11585	COG0367	asparagine synthase
LacP0625_RS11610	COG0142	geranyltranstransferase activity
LacP0625_RS11620	COG4152	abc transporter atp-binding protein
LacP0625_RS11660	COG1297	OPT oligopeptide transporter protein
LacP0625_RS11690	COG2723	6-phospho-beta-galactosidase activity
LacP0625_RS11695	COG2190	(PTS) system
LacP0625_RS11695	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LacP0625_RS11695	COG1263	PTS System
LacP0625_RS11705	COG1132	(ABC) transporter
LacP0625_RS11710	COG1132	(ABC) transporter
LacP0625_RS11745	COG1518	maintenance of DNA repeat elements
LacP0625_RS11750	COG3513	CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
LacP0625_RS11775	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
LacP0625_RS11780	COG4988	ABC transporter
LacP0625_RS11785	COG1294	oxidase, subunit
LacP0625_RS11790	COG1271	oxidase subunit
LacP0625_RS11820	COG0697	spore germination
LacP0625_RS11825	COG2818	Glycosylase
LacP0625_RS11840	COG2365	Tyrosine phosphatase family
LacP0625_RS11845	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
LacP0625_RS11855	COG1268	BioY protein
LacP0625_RS11860	COG0789	Transcriptional regulator
LacP0625_RS11870	COG1063	alcohol dehydrogenase
LacP0625_RS11890	COG2264	protein methyltransferase activity
LacP0625_RS11900	COG0505	Belongs to the CarA family
LacP0625_RS11910	COG1253	flavin adenine dinucleotide binding
LacP0625_RS11915	COG2814	Major facilitator Superfamily
LacP0625_RS11940	COG0531	amino acid
LacP0625_RS11960	COG1266	CAAX protease self-immunity
LacP0625_RS11965	COG1316	TRANSCRIPTIONal
LacP0625_RS11975	COG1131	(ABC) transporter
LacP0625_RS11980	COG1725	Transcriptional regulator
LacP0625_RS11985	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
LacP0625_RS11990	COG0488	(ABC) transporter
LacP0625_RS11995	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
LacP0625_RS12005	COG0456	acetyltransferase
LacP0625_RS12005	COG1214	PFAM Peptidase M22, glycoprotease
LacP0625_RS12010	COG1214	PFAM Peptidase M22, glycoprotease
LacP0625_RS12045	COG0470	DNA polymerase III
LacP0625_RS12050	COG3870	Protein conserved in bacteria
LacP0625_RS12075	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
LacP0625_RS12085	COG0590	tRNA wobble adenosine to inosine editing
LacP0625_RS12095	COG2813	Specifically methylates the guanine in position
LacP0625_RS12100	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
LacP0625_RS12100	COG0392	lysyltransferase activity
LacP0625_RS12110	COG1609	Transcriptional regulator
LacP0625_RS12150	COG0477	Major facilitator Superfamily
LacP0625_RS12155	COG1012	belongs to the aldehyde dehydrogenase family
LacP0625_RS12170	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
LacP0625_RS12180	COG5646	InterPro IPR014922
LacP0625_RS12185	COG2096	Adenosyltransferase
LacP0625_RS12215	COG0250	Participates in transcription elongation, termination and antitermination
LacP0625_RS12245	COG4939	FMN-binding domain protein
LacP0625_RS12290	COG3688	RNA-binding protein containing a PIN domain
LacP0625_RS12295	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LacP0625_RS12300	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
LacP0625_RS12310	COG0277	FAD linked oxidase domain protein
LacP0625_RS12335	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
LacP0625_RS12340	COG1737	Transcriptional regulator
LacP0625_RS12345	COG4377	Putative membrane peptidase family (DUF2324)
LacP0625_RS12360	COG4932	domain protein
LacP0625_RS12360	COG4886	Leucine-rich repeat (LRR) protein
LacP0625_RS12370	COG1131	(ABC) transporter
LacP0625_RS12375	COG4956	integral membrane protein (PIN domain superfamily)
LacP0625_RS12380	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
LacP0625_RS12385	COG0756	dUTP diphosphatase activity
LacP0625_RS12390	COG2388	GCN5-related N-acetyl-transferase
LacP0625_RS12395	COG3152	Membrane
LacP0625_RS12420	COG1131	(ABC) transporter
LacP0625_RS12430	COG0574	Belongs to the PEP-utilizing enzyme family
LacP0625_RS12430	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
LacP0625_RS12435	COG0517	IMP dehydrogenase activity
LacP0625_RS12440	COG0588	phosphoglycerate mutase activity
LacP0625_RS12455	COG1304	FMN binding
LacP0625_RS12490	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
LacP0625_RS12510	COG3764	Sortase (surface protein transpeptidase)
LacP0625_RS12550	COG1695	Transcriptional regulator
LacP0625_RS12595	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LacP0625_RS12600	COG2274	protein secretion by the type I secretion system
LacP0625_RS12690	COG0110	maltose O-acetyltransferase activity
LacP0625_RS12710	COG4989	oxidoreductase activity
LacP0625_RS12715	COG4221	oxidoreductase activity
LacP0625_RS12720	COG1902	pentaerythritol trinitrate reductase activity
LacP0625_RS12725	COG0114	fumarate hydratase activity
LacP0625_RS12740	COG1914	H( )-stimulated, divalent metal cation uptake system
LacP0625_RS12745	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
LacP0625_RS12755	COG2814	Major facilitator Superfamily
LacP0625_RS12785	COG1108	ABC-type Mn2 Zn2 transport systems permease components
LacP0625_RS12790	COG1121	(ABC) transporter
LacP0625_RS12795	COG1012	belongs to the aldehyde dehydrogenase family
LacP0625_RS12870	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
LacP0625_RS12880	COG0148	phosphopyruvate hydratase activity
LacP0625_RS12900	COG3639	organic phosphonate transmembrane transporter activity
LacP0625_RS12920	COG1116	anion transmembrane transporter activity
LacP0625_RS12925	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
LacP0625_RS12940	COG4555	ABC transporter
LacP0625_RS12980	COG0577	efflux transmembrane transporter activity
LacP0625_RS12985	COG1136	(ABC) transporter
LacP0625_RS12995	COG0789	Transcriptional regulator
LacP0625_RS13065	COG0200	Binds to the 23S rRNA
LacP0625_RS13175	COG0450	alkyl hydroperoxide reductase
LacP0625_RS13220	COG0542	response to heat
LacP0625_RS13225	COG4463	regulation of RNA biosynthetic process
LacP0625_RS13295	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
LacP0625_RS13300	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
LacP0625_RS13340	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
LacP0625_RS13345	COG0037	tRNA processing
LacP0625_RS13350	COG1098	S1 RNA binding domain
LacP0625_RS13360	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
LacP0625_RS13365	COG2244	polysaccharide biosynthetic process
LacP0625_RS13370	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
LacP0625_RS13380	COG0039	L-malate dehydrogenase activity
LacP0625_RS13395	COG1376	ErfK ybiS ycfS ynhG family protein
LacP0625_RS13405	COG0493	'glutamate synthase
LacP0625_RS13410	COG0069	glutamate synthase activity
LacP0625_RS13410	COG0067	glutamate synthase
LacP0625_RS13410	COG0070	glutamate synthase
LacP0625_RS13415	COG4708	membrane
LacP0625_RS13420	COG2337	Toxic component of a toxin-antitoxin (TA) module
LacP0625_RS13450	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
LacP0625_RS13515	COG1674	ftsk spoiiie
LacP0625_RS13530	COG1196	nuclear chromosome segregation
LacP0625_RS13535	COG2946	Replication initiation factor
LacP0625_RS13565	COG0433	COG0433 Predicted ATPase
LacP0625_RS13575	COG0741	lytic transglycosylase activity
LacP0625_RS13575	COG0791	NLP P60 protein
LacP0625_RS13625	COG3867	Arabinogalactan endo-beta-1,4-galactanase
LacP0625_RS13630	COG1447	Phosphotransferase system cellobiose-specific component IIA
LacP0625_RS13635	COG2723	6-phospho-beta-galactosidase activity
LacP0625_RS13640	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
LacP0625_RS13640	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
LacP0625_RS13645	COG1609	Transcriptional regulator
LacP0625_RS13655	COG0277	FAD linked oxidase domain protein
LacP0625_RS13665	COG2801	Transposase and inactivated derivatives
LacP0625_RS13710	COG0218	Necessary for normal cell division and for the maintenance of normal septation
LacP0625_RS13770	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
LacP0625_RS13775	COG0504	CTP synthase activity
LacP0625_RS13795	COG0095	Lipoate-protein ligase
LacP0625_RS13800	COG1078	dGTPase activity
LacP0625_RS13820	COG1228	amidohydrolase
LacP0625_RS13825	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
LacP0625_RS13845	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
LacP0625_RS13850	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
LacP0625_RS13860	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
LacP0625_RS13865	COG4619	ABC transporter
LacP0625_RS13870	COG0390	transport system, permease component
LacP0625_RS13880	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
LacP0625_RS13885	COG4466	Protein conserved in bacteria
LacP0625_RS13890	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
LacP0625_RS13895	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
LacP0625_RS13900	COG0084	hydrolase, TatD family'
LacP0625_RS13910	COG3684	Belongs to the aldolase LacD family
LacP0625_RS13925	COG3290	protein histidine kinase activity
LacP0625_RS13940	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LacP0625_RS13940	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LacP0625_RS13950	COG1801	Protein of unknown function DUF72
LacP0625_RS13970	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
LacP0625_RS13990	COG1881	PFAM PEBP family protein
LacP0625_RS14000	COG4086	secreted protein
LacP0625_RS14005	COG0248	Ppx GppA phosphatase
LacP0625_RS14010	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
LacP0625_RS14020	COG4989	oxidoreductase activity
LacP0625_RS14025	COG2226	methyltransferase
LacP0625_RS14035	COG0534	Mate efflux family protein
LacP0625_RS14040	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
LacP0625_RS14045	COG1704	LemA family
LacP0625_RS14065	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LacP0625_RS14075	COG1174	glycine betaine transport
LacP0625_RS14080	COG3973	AAA domain
LacP0625_RS14105	COG1418	mRNA catabolic process
LacP0625_RS14115	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
LacP0625_RS14120	COG0667	Aldo Keto reductase
LacP0625_RS14145	COG0588	phosphoglycerate mutase activity
LacP0625_RS14150	COG0561	phosphatase activity
LacP0625_RS14165	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LacP0625_RS14170	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
LacP0625_RS14175	COG1811	Na channel or pump
LacP0625_RS14185	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LacP0625_RS14185	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LacP0625_RS14185	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
LacP0625_RS14190	COG1105	Belongs to the carbohydrate kinase PfkB family
LacP0625_RS14210	COG1122	ATPase activity
LacP0625_RS14220	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
LacP0625_RS14240	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LacP0625_RS14240	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
LacP0625_RS14245	COG3715	PTS system
LacP0625_RS14250	COG3716	PTS system mannose fructose sorbose family IID component
LacP0625_RS14255	COG1447	Phosphotransferase system cellobiose-specific component IIA
LacP0625_RS14265	COG2723	6-phospho-beta-galactosidase activity
LacP0625_RS14285	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
LacP0625_RS14290	COG2188	Transcriptional regulator
LacP0625_RS14305	COG3775	system Galactitol-specific IIC component
LacP0625_RS14320	COG1349	DNA-binding transcription factor activity
LacP0625_RS14370	COG3716	PTS system mannose fructose sorbose family IID component
LacP0625_RS14375	COG3715	PTS system
LacP0625_RS14380	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LacP0625_RS14385	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
LacP0625_RS14395	COG1414	Transcriptional regulator
LacP0625_RS14405	COG1028	Short-chain dehydrogenase reductase Sdr
LacP0625_RS14410	COG0800	Aldolase
LacP0625_RS14435	COG0463	Glycosyl transferase, family 2
LacP0625_RS14445	COG0586	Pfam SNARE associated Golgi protein
LacP0625_RS14450	COG5002	protein histidine kinase activity
LacP0625_RS14455	COG0745	RESPONSE REGULATOR receiver
LacP0625_RS14465	COG1263	PTS System
LacP0625_RS14465	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LacP0625_RS14495	COG3711	transcriptional antiterminator
LacP0625_RS14505	COG1263	PTS System
LacP0625_RS14505	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LacP0625_RS14505	COG2190	(PTS) system
LacP0625_RS14530	COG3414	Phosphotransferase system galactitol-specific IIB component
LacP0625_RS14535	COG3775	system Galactitol-specific IIC component
LacP0625_RS14570	COG3964	amidohydrolase
LacP0625_RS14615	COG3732	PTS system glucitol sorbitol-specific
LacP0625_RS14620	COG3730	PTS system glucitol sorbitol-specific
LacP0625_RS14640	COG1879	ABC-type sugar transport system periplasmic component
LacP0625_RS14645	COG1172	Belongs to the binding-protein-dependent transport system permease family
LacP0625_RS14655	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
LacP0625_RS14660	COG3958	Transketolase
LacP0625_RS14665	COG3959	Transketolase, thiamine diphosphate binding domain
LacP0625_RS14675	COG1609	Transcriptional regulator
LacP0625_RS14685	COG0561	phosphatase activity
LacP0625_RS14690	COG3623	hexulose-6-phosphate isomerase
LacP0625_RS14695	COG1349	DNA-binding transcription factor activity
LacP0625_RS14700	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
LacP0625_RS14715	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
LacP0625_RS14735	COG3775	system Galactitol-specific IIC component
LacP0625_RS14745	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
LacP0625_RS14750	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
LacP0625_RS14755	COG1349	DNA-binding transcription factor activity
LacP0625_RS14770	COG1446	asparaginase
LacP0625_RS14775	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
LacP0625_RS14780	COG2188	Transcriptional regulator
LacP0625_RS14810	COG0477	Major facilitator Superfamily
LacP0625_RS14815	COG0456	acetyltransferase
LacP0625_RS14855	COG0584	glycerophosphoryl diester phosphodiesterase
LacP0625_RS14860	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
LacP0625_RS14870	COG0395	ABC-type sugar transport system, permease component
LacP0625_RS14880	COG3842	ATPase activity
LacP0625_RS14885	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
LacP0625_RS14890	COG1335	isochorismatase
LacP0625_RS14905	COG4948	Mandelate Racemase Muconate Lactonizing
LacP0625_RS14915	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
LacP0625_RS14920	COG1737	Transcriptional regulator
LacP0625_RS14925	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LacP0625_RS14930	COG3716	PTS system mannose fructose sorbose family IID component
LacP0625_RS14945	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
LacP0625_RS14955	COG2076	Multidrug Resistance protein
LacP0625_RS14980	COG0604	alcohol dehydrogenase
LacP0625_RS14985	COG2365	Tyrosine phosphatase family
LacP0625_RS14995	COG0789	Transcriptional regulator
LacP0625_RS15000	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LacP0625_RS15025	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
LacP0625_RS15040	COG4166	transmembrane transport
LacP0625_RS15050	COG2217	Heavy metal translocating P-type atpase
LacP0625_RS15065	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LacP0625_RS15070	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
LacP0625_RS15085	COG5002	protein histidine kinase activity
LacP0625_RS15090	COG0745	RESPONSE REGULATOR receiver
LacP0625_RS15095	COG0596	Alpha beta hydrolase
LacP0625_RS15100	COG0765	amino acid transport
LacP0625_RS15125	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
LacP0625_RS15130	COG2188	Transcriptional regulator
LacP0625_RS15135	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
LacP0625_RS15140	COG1447	Phosphotransferase system cellobiose-specific component IIA
LacP0625_RS15160	COG1335	isochorismatase
LacP0625_RS15165	COG2814	Major facilitator Superfamily
LacP0625_RS15170	COG2807	transmembrane transport
LacP0625_RS15175	COG0667	Aldo Keto reductase
LacP0625_RS15185	COG3716	PTS system mannose fructose sorbose family IID component
LacP0625_RS15190	COG3715	PTS system
LacP0625_RS15225	COG0765	amino acid transport
LacP0625_RS15230	COG1126	abc transporter atp-binding protein
LacP0625_RS15275	COG3001	Fructosamine kinase
LacP0625_RS15285	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LacP0625_RS15290	COG0765	amino acid transport
LacP0625_RS15305	COG0714	Associated with various cellular activities
LacP0625_RS15315	COG1305	Transglutaminase-like
LacP0625_RS15320	COG0438	transferase activity, transferring glycosyl groups
LacP0625_RS15325	COG0110	maltose O-acetyltransferase activity
LacP0625_RS15330	COG0561	phosphatase activity
LacP0625_RS15355	COG3493	citrate carrier protein
LacP0625_RS15360	COG3290	protein histidine kinase activity
LacP0625_RS15365	COG4565	transcriptional regulatory protein
LacP0625_RS15400	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
LacP0625_RS15420	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
LacP0625_RS15430	COG2213	PTS system mannitol-specific
LacP0625_RS15440	COG0561	phosphatase activity
LacP0625_RS15460	COG0577	efflux transmembrane transporter activity
LacP0625_RS15460	COG1136	(ABC) transporter
LacP0625_RS15465	COG0577	efflux transmembrane transporter activity
LacP0625_RS15475	COG0371	Dehydrogenase
LacP0625_RS15480	COG1473	amidohydrolase
LacP0625_RS15515	COG0706	membrane insertase activity
LacP0625_RS15530	COG0366	Alpha amylase catalytic
LacP0625_RS15540	COG1175	transmembrane transport
LacP0625_RS15545	COG3833	ABC-type maltose transport systems, permease component
LacP0625_RS15550	COG1609	Transcriptional regulator
LacP0625_RS15630	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
LacP0625_RS15635	COG2337	Toxic component of a toxin-antitoxin (TA) module
LacP0625_RS15690	COG0366	Alpha amylase catalytic
LacP0625_RS15705	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
LacP0625_RS15710	COG3842	ATPase activity