locus-tag	class	description
LacP0747_RS00010	COG0592	DNA-directed DNA polymerase activity
LacP0747_RS00015	COG2501	S4 domain
LacP0747_RS00025	COG0187	DNA topoisomerase II activity
LacP0747_RS00035	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
LacP0747_RS00050	COG0629	single-stranded DNA binding
LacP0747_RS00060	COG1271	oxidase subunit
LacP0747_RS00065	COG1294	oxidase, subunit
LacP0747_RS00105	COG3942	CHAP domain
LacP0747_RS00125	COG0561	phosphatase activity
LacP0747_RS00145	COG3409	Peptidoglycan-binding domain 1 protein
LacP0747_RS00260	COG0800	Aldolase
LacP0747_RS00295	COG2814	Major facilitator Superfamily
LacP0747_RS00305	COG2409	Drug exporters of the RND superfamily
LacP0747_RS00305	COG1033	growth of symbiont in host cell
LacP0747_RS00310	COG1309	transcriptional regulator
LacP0747_RS00325	COG1732	Glycine betaine
LacP0747_RS00360	COG2217	Heavy metal translocating P-type atpase
LacP0747_RS00370	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
LacP0747_RS00375	COG0159	tryptophan synthase activity
LacP0747_RS00380	COG0133	tryptophan synthase activity
LacP0747_RS00385	COG0135	phosphoribosylanthranilate isomerase activity
LacP0747_RS00390	COG0134	indole-3-glycerol-phosphate synthase activity
LacP0747_RS00405	COG2814	Major facilitator Superfamily
LacP0747_RS00440	COG1131	(ABC) transporter
LacP0747_RS00465	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
LacP0747_RS00485	COG0019	diaminopimelate decarboxylase activity
LacP0747_RS00490	COG0527	aspartate kinase activity
LacP0747_RS00495	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
LacP0747_RS00500	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
LacP0747_RS00545	COG0305	Participates in initiation and elongation during chromosome replication
LacP0747_RS00560	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
LacP0747_RS00565	COG1737	Transcriptional regulator
LacP0747_RS00570	COG1309	transcriptional regulator
LacP0747_RS00575	COG1136	(ABC) transporter
LacP0747_RS00575	COG0577	efflux transmembrane transporter activity
LacP0747_RS00595	COG2217	Heavy metal translocating P-type atpase
LacP0747_RS00600	COG0640	Transcriptional regulator
LacP0747_RS00605	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
LacP0747_RS00610	COG0583	DNA-binding transcription factor activity
LacP0747_RS00615	COG1395	domain, Protein
LacP0747_RS00625	COG1131	(ABC) transporter
LacP0747_RS00635	COG1328	CTP reductase activity
LacP0747_RS00715	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
LacP0747_RS00750	COG2252	PERMEase
LacP0747_RS00765	COG1116	anion transmembrane transporter activity
LacP0747_RS00770	COG4521	taurine ABC transporter
LacP0747_RS00790	COG0446	pyridine nucleotide-disulphide oxidoreductase
LacP0747_RS00795	COG2391	methyltransferase activity
LacP0747_RS00810	COG0346	lactoylglutathione lyase activity
LacP0747_RS00870	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
LacP0747_RS00895	COG1511	domain protein
LacP0747_RS00895	COG1511	domain protein
LacP0747_RS00905	COG0477	Major facilitator Superfamily
LacP0747_RS00915	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
LacP0747_RS00920	COG4166	transmembrane transport
LacP0747_RS00940	COG1131	(ABC) transporter
LacP0747_RS00960	COG1132	(ABC) transporter
LacP0747_RS00965	COG1396	sequence-specific DNA binding
LacP0747_RS00975	COG0446	pyridine nucleotide-disulphide oxidoreductase
LacP0747_RS01015	COG0716	FMN binding
LacP0747_RS01030	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LacP0747_RS01040	COG2261	transglycosylase associated protein
LacP0747_RS01055	COG1302	Protein conserved in bacteria
LacP0747_RS01085	COG3442	glutamine amidotransferase
LacP0747_RS01105	COG1192	Involved in chromosome partitioning
LacP0747_RS01110	COG1475	DNA binding
LacP0747_RS01115	COG4481	Protein conserved in bacteria
LacP0747_RS01120	COG0012	GTP binding
LacP0747_RS01130	COG0516	GMP reductase activity
LacP0747_RS01130	COG0517	IMP dehydrogenase activity
LacP0747_RS01150	COG1686	Belongs to the peptidase S11 family
LacP0747_RS01155	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
LacP0747_RS01165	COG1794	racemase activity, acting on amino acids and derivatives
LacP0747_RS01170	COG0656	L-ascorbic acid biosynthetic process
LacP0747_RS01175	COG1349	DNA-binding transcription factor activity
LacP0747_RS01180	COG2814	Major facilitator Superfamily
LacP0747_RS01185	COG1012	belongs to the aldehyde dehydrogenase family
LacP0747_RS01190	COG3718	enzyme involved in inositol metabolism
LacP0747_RS01195	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LacP0747_RS01200	COG3962	Belongs to the TPP enzyme family
LacP0747_RS01205	COG0673	inositol 2-dehydrogenase activity
LacP0747_RS01210	COG0673	inositol 2-dehydrogenase activity
LacP0747_RS01220	COG0191	fructose-bisphosphate aldolase activity
LacP0747_RS01225	COG1942	4-Oxalocrotonate Tautomerase
LacP0747_RS01230	COG1737	Transcriptional regulator
LacP0747_RS01235	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
LacP0747_RS01245	COG2610	gluconate transmembrane transporter activity
LacP0747_RS01255	COG1121	(ABC) transporter
LacP0747_RS01270	COG2084	Dehydrogenase
LacP0747_RS01275	COG1164	Oligoendopeptidase f
LacP0747_RS01280	COG1316	TRANSCRIPTIONal
LacP0747_RS01285	COG1114	Component of the transport system for branched-chain amino acids
LacP0747_RS01300	COG1216	Glycosyl transferase, family 2
LacP0747_RS01325	COG0488	(ABC) transporter
LacP0747_RS01350	COG3118	belongs to the thioredoxin family
LacP0747_RS01365	COG0683	leucine binding
LacP0747_RS01395	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
LacP0747_RS01405	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
LacP0747_RS01410	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
LacP0747_RS01435	COG2723	6-phospho-beta-galactosidase activity
LacP0747_RS01440	COG0446	pyridine nucleotide-disulphide oxidoreductase
LacP0747_RS01460	COG2182	Extracellular solute-binding protein
LacP0747_RS01470	COG3064	Membrane
LacP0747_RS01470	COG3583	domain protein
LacP0747_RS01470	COG3525	Glycosyl hydrolase, family 20, catalytic domain
LacP0747_RS01475	COG1482	cell wall glycoprotein biosynthetic process
LacP0747_RS01480	COG2188	Transcriptional regulator
LacP0747_RS01485	COG2222	sugar isomerase
LacP0747_RS01490	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
LacP0747_RS01505	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LacP0747_RS01510	COG3715	PTS system
LacP0747_RS01515	COG3716	PTS system mannose fructose sorbose family IID component
LacP0747_RS01520	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
LacP0747_RS01520	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LacP0747_RS01530	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
LacP0747_RS01535	COG0006	proline dipeptidase activity
LacP0747_RS01540	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
LacP0747_RS01545	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
LacP0747_RS01550	COG1447	Phosphotransferase system cellobiose-specific component IIA
LacP0747_RS01555	COG1363	Peptidase, m42
LacP0747_RS01565	COG2195	Cleaves the N-terminal amino acid of tripeptides
LacP0747_RS01570	COG4166	transmembrane transport
LacP0747_RS01595	COG1129	ABC transporter
LacP0747_RS01605	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
LacP0747_RS01625	COG0351	phosphomethylpyrimidine kinase
LacP0747_RS01630	COG0531	amino acid
LacP0747_RS01640	COG1609	Transcriptional regulator
LacP0747_RS01655	COG1172	Belongs to the binding-protein-dependent transport system permease family
LacP0747_RS01660	COG1879	ABC-type sugar transport system periplasmic component
LacP0747_RS01680	COG2814	Major facilitator Superfamily
LacP0747_RS01720	COG1131	(ABC) transporter
LacP0747_RS01740	COG1053	succinate dehydrogenase
LacP0747_RS01745	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
LacP0747_RS01775	COG1378	Sugar-specific transcriptional regulator TrmB
LacP0747_RS01790	COG2267	carboxylic ester hydrolase activity
LacP0747_RS01825	COG1609	Transcriptional regulator
LacP0747_RS01835	COG3716	PTS system mannose fructose sorbose family IID component
LacP0747_RS01845	COG1262	PFAM Formylglycine-generating sulfatase enzyme
LacP0747_RS01855	COG0641	radical SAM
LacP0747_RS01865	COG3716	PTS system mannose fructose sorbose family IID component
LacP0747_RS01870	COG3715	PTS system
LacP0747_RS01875	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LacP0747_RS01905	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
LacP0747_RS01910	COG3711	transcriptional antiterminator
LacP0747_RS01915	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
LacP0747_RS01915	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
LacP0747_RS01925	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LacP0747_RS01925	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LacP0747_RS01925	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
LacP0747_RS01930	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LacP0747_RS01935	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
LacP0747_RS01935	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LacP0747_RS01935	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LacP0747_RS01955	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LacP0747_RS01955	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LacP0747_RS01955	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
LacP0747_RS01960	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LacP0747_RS01960	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LacP0747_RS01965	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
LacP0747_RS01980	COG0191	fructose-bisphosphate aldolase activity
LacP0747_RS01985	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LacP0747_RS01985	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
LacP0747_RS01985	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LacP0747_RS01990	COG1028	Short-chain dehydrogenase reductase Sdr
LacP0747_RS02000	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
LacP0747_RS02000	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LacP0747_RS02005	COG3715	PTS system
LacP0747_RS02010	COG3716	PTS system mannose fructose sorbose family IID component
LacP0747_RS02015	COG0246	Mannitol dehydrogenase
LacP0747_RS02020	COG1461	Dihydroxyacetone kinase
LacP0747_RS02025	COG2376	Dihydroxyacetone kinase
LacP0747_RS02030	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
LacP0747_RS02035	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
LacP0747_RS02040	COG1609	Transcriptional regulator
LacP0747_RS02050	COG2390	Transcriptional regulator
LacP0747_RS02060	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
LacP0747_RS02065	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LacP0747_RS02070	COG3715	PTS system
LacP0747_RS02075	COG3716	PTS system mannose fructose sorbose family IID component
LacP0747_RS02080	COG0191	fructose-bisphosphate aldolase activity
LacP0747_RS02085	COG0471	metal ion transport
LacP0747_RS02095	COG0583	DNA-binding transcription factor activity
LacP0747_RS02110	COG1122	ATPase activity
LacP0747_RS02165	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
LacP0747_RS02170	COG1349	DNA-binding transcription factor activity
LacP0747_RS02175	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
LacP0747_RS02180	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
LacP0747_RS02185	COG1349	DNA-binding transcription factor activity
LacP0747_RS02215	COG0477	Major facilitator Superfamily
LacP0747_RS02235	COG4221	oxidoreductase activity
LacP0747_RS02260	COG0446	pyridine nucleotide-disulphide oxidoreductase
LacP0747_RS02265	COG0561	phosphatase activity
LacP0747_RS02275	COG1609	Transcriptional regulator
LacP0747_RS02280	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LacP0747_RS02290	COG3716	PTS system mannose fructose sorbose family IID component
LacP0747_RS02310	COG0366	Alpha amylase catalytic
LacP0747_RS02315	COG1132	(ABC) transporter
LacP0747_RS02335	COG1464	Belongs to the NlpA lipoprotein family
LacP0747_RS02360	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
LacP0747_RS02365	COG1461	Dihydroxyacetone kinase
LacP0747_RS02370	COG2376	Dihydroxyacetone kinase
LacP0747_RS02395	COG2814	Major facilitator Superfamily
LacP0747_RS02415	COG0028	Belongs to the TPP enzyme family
LacP0747_RS02430	COG2226	methyltransferase
LacP0747_RS02435	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
LacP0747_RS02440	COG0174	glutamine synthetase
LacP0747_RS02455	COG0789	Transcriptional regulator
LacP0747_RS02460	COG0656	L-ascorbic acid biosynthetic process
LacP0747_RS02475	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
LacP0747_RS02500	COG1131	(ABC) transporter
LacP0747_RS02520	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
LacP0747_RS02545	COG0308	aminopeptidase N
LacP0747_RS02550	COG0531	amino acid
LacP0747_RS02570	COG1028	Short-chain dehydrogenase reductase Sdr
LacP0747_RS02580	COG2271	Major facilitator Superfamily
LacP0747_RS02585	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
LacP0747_RS02590	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
LacP0747_RS02595	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
LacP0747_RS02740	COG2826	transposase and inactivated derivatives, IS30 family
LacP0747_RS02770	COG2801	Transposase and inactivated derivatives
LacP0747_RS02955	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
LacP0747_RS03000	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
LacP0747_RS03020	COG0783	Belongs to the Dps family
LacP0747_RS03030	COG2801	Transposase and inactivated derivatives
LacP0747_RS03040	COG3976	FMN-binding domain protein
LacP0747_RS03040	COG0431	NADPH-dependent FMN reductase
LacP0747_RS03040	COG1053	succinate dehydrogenase
LacP0747_RS03090	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
LacP0747_RS03115	COG4619	ABC transporter
LacP0747_RS03120	COG0390	transport system, permease component
LacP0747_RS03145	COG1174	glycine betaine transport
LacP0747_RS03155	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LacP0747_RS03170	COG0626	cystathionine gamma-synthase activity
LacP0747_RS03175	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LacP0747_RS03180	COG0765	amino acid transport
LacP0747_RS03190	COG1114	Component of the transport system for branched-chain amino acids
LacP0747_RS03235	COG0697	spore germination
LacP0747_RS03245	COG1131	(ABC) transporter
LacP0747_RS03260	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
LacP0747_RS03265	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
LacP0747_RS03270	COG1132	(ABC) transporter
LacP0747_RS03275	COG1132	(ABC) transporter
LacP0747_RS03280	COG2223	nitrite transmembrane transporter activity
LacP0747_RS03285	COG2188	Transcriptional regulator
LacP0747_RS03290	COG0366	Alpha amylase catalytic
LacP0747_RS03295	COG1263	PTS System
LacP0747_RS03295	COG2190	(PTS) system
LacP0747_RS03295	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LacP0747_RS03305	COG0531	amino acid
LacP0747_RS03310	COG0039	L-malate dehydrogenase activity
LacP0747_RS03315	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
LacP0747_RS03320	COG1278	Cold shock
LacP0747_RS03335	COG0488	(ABC) transporter
LacP0747_RS03340	COG0702	epimerase
LacP0747_RS03345	COG0656	L-ascorbic acid biosynthetic process
LacP0747_RS03350	COG1113	amino acid transport
LacP0747_RS03360	COG0025	NhaP-type Na H and K H
LacP0747_RS03405	COG0004	ammonium transporteR
LacP0747_RS03415	COG1285	pathogenesis
LacP0747_RS03435	COG1131	(ABC) transporter
LacP0747_RS03445	COG0488	(ABC) transporter
LacP0747_RS03450	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
LacP0747_RS03455	COG1573	uracil-dna glycosylase
LacP0747_RS03460	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
LacP0747_RS03465	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
LacP0747_RS03470	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
LacP0747_RS03475	COG1215	transferase activity, transferring glycosyl groups
LacP0747_RS03485	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
LacP0747_RS03490	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
LacP0747_RS03495	COG1609	Transcriptional regulator
LacP0747_RS03500	COG2017	converts alpha-aldose to the beta-anomer
LacP0747_RS03525	COG3775	system Galactitol-specific IIC component
LacP0747_RS03545	COG3684	Belongs to the aldolase LacD family
LacP0747_RS03560	COG1349	DNA-binding transcription factor activity
LacP0747_RS03575	COG0419	ATPase involved in DNA repair
LacP0747_RS03595	COG1194	a g-specific adenine glycosylase
LacP0747_RS03605	COG2249	NAD(P)H dehydrogenase (quinone) activity
LacP0747_RS03625	COG0351	phosphomethylpyrimidine kinase
LacP0747_RS03640	COG2910	NAD(P)H-binding
LacP0747_RS03645	COG1472	Belongs to the glycosyl hydrolase 3 family
LacP0747_RS03660	COG4120	Belongs to the binding-protein-dependent transport system permease family
LacP0747_RS03670	COG0604	alcohol dehydrogenase
LacP0747_RS03685	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
LacP0747_RS03695	COG0745	RESPONSE REGULATOR receiver
LacP0747_RS03700	COG5002	protein histidine kinase activity
LacP0747_RS03710	COG2508	Transcriptional regulator
LacP0747_RS03725	COG0778	Nitroreductase
LacP0747_RS03765	COG0604	alcohol dehydrogenase
LacP0747_RS03780	COG0628	permease
LacP0747_RS03805	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
LacP0747_RS03815	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
LacP0747_RS03820	COG3189	MarR family transcriptional regulator
LacP0747_RS03845	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
LacP0747_RS03870	COG0300	oxidoreductase activity
LacP0747_RS03875	COG0105	UTP biosynthetic process
LacP0747_RS03880	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
LacP0747_RS03885	COG2267	carboxylic ester hydrolase activity
LacP0747_RS03915	COG2267	carboxylic ester hydrolase activity
LacP0747_RS03950	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
LacP0747_RS03975	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
LacP0747_RS03980	COG0343	queuine tRNA-ribosyltransferase activity
LacP0747_RS03985	COG1862	Preprotein translocase
LacP0747_RS03990	COG1454	alcohol dehydrogenase
LacP0747_RS03990	COG1012	belongs to the aldehyde dehydrogenase family
LacP0747_RS04000	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
LacP0747_RS04005	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
LacP0747_RS04010	COG4109	DRTGG domain
LacP0747_RS04015	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
LacP0747_RS04020	COG0513	Belongs to the DEAD box helicase family
LacP0747_RS04065	COG3118	belongs to the thioredoxin family
LacP0747_RS04080	COG1696	Membrane protein involved in D-alanine export
LacP0747_RS04090	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
LacP0747_RS04095	COG1719	4-vinyl reductase, 4VR
LacP0747_RS04100	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
LacP0747_RS04110	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
LacP0747_RS04125	COG0668	transmembrane transport
LacP0747_RS04140	COG1827	regulation of RNA biosynthetic process
LacP0747_RS04145	COG0006	proline dipeptidase activity
LacP0747_RS04150	COG1609	Transcriptional regulator
LacP0747_RS04155	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
LacP0747_RS04160	COG1011	Hydrolase
LacP0747_RS04205	COG0737	Belongs to the 5'-nucleotidase family
LacP0747_RS04210	COG4470	Protein conserved in bacteria
LacP0747_RS04215	COG0647	UMP catabolic process
LacP0747_RS04225	COG0586	Pfam SNARE associated Golgi protein
LacP0747_RS04230	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
LacP0747_RS04245	COG1098	S1 RNA binding domain
LacP0747_RS04395	COG0531	amino acid
LacP0747_RS04400	COG0438	transferase activity, transferring glycosyl groups
LacP0747_RS04405	COG0438	transferase activity, transferring glycosyl groups
LacP0747_RS04420	COG0436	Aminotransferase
LacP0747_RS04430	COG1368	sulfuric ester hydrolase activity
LacP0747_RS04435	COG0735	belongs to the Fur family
LacP0747_RS04480	COG0477	Major facilitator Superfamily
LacP0747_RS04490	COG2814	Major facilitator Superfamily
LacP0747_RS04500	COG0671	phosphoesterase, PA-phosphatase related
LacP0747_RS04510	COG2244	polysaccharide biosynthetic process
LacP0747_RS04515	COG1187	pseudouridine synthase activity
LacP0747_RS04525	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
LacP0747_RS04545	COG0438	transferase activity, transferring glycosyl groups
LacP0747_RS04550	COG0386	Belongs to the glutathione peroxidase family
LacP0747_RS04555	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
LacP0747_RS04565	COG3830	Belongs to the UPF0237 family
LacP0747_RS04590	COG2357	RelA SpoT domain protein
LacP0747_RS04600	COG0564	pseudouridine synthase activity
LacP0747_RS04610	COG3142	Participates in the control of copper homeostasis
LacP0747_RS04620	COG2706	6-phosphogluconolactonase activity
LacP0747_RS04630	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
LacP0747_RS04645	COG2226	methyltransferase
LacP0747_RS04650	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
LacP0747_RS04660	COG1674	ftsk spoiiie
LacP0747_RS04665	COG0612	Peptidase, M16
LacP0747_RS04670	COG0612	Peptidase, M16
LacP0747_RS04675	COG1028	Short-chain dehydrogenase reductase Sdr
LacP0747_RS04680	COG1426	Protein conserved in bacteria
LacP0747_RS04685	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
LacP0747_RS04695	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
LacP0747_RS04710	COG1739	Uncharacterized protein family UPF0029
LacP0747_RS04715	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
LacP0747_RS04740	COG2884	Cell division ATP-binding protein ftsE
LacP0747_RS04745	COG2177	Part of the ABC transporter FtsEX involved in
LacP0747_RS04755	COG0745	RESPONSE REGULATOR receiver
LacP0747_RS04760	COG5002	protein histidine kinase activity
LacP0747_RS04770	COG0573	inorganic phosphate transmembrane transporter activity
LacP0747_RS04775	COG0581	inorganic phosphate transmembrane transporter activity
LacP0747_RS04780	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
LacP0747_RS04785	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
LacP0747_RS04790	COG0704	Plays a role in the regulation of phosphate uptake
LacP0747_RS04805	COG1950	PFAM Membrane protein of
LacP0747_RS04815	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
LacP0747_RS04825	COG0492	ferredoxin-NADP+ reductase activity
LacP0747_RS04830	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
LacP0747_RS04835	COG0745	RESPONSE REGULATOR receiver
LacP0747_RS04840	COG2205	protein histidine kinase activity
LacP0747_RS04845	COG1136	(ABC) transporter
LacP0747_RS04865	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
LacP0747_RS04880	COG0391	Required for morphogenesis under gluconeogenic growth conditions
LacP0747_RS04890	COG1846	Transcriptional regulator
LacP0747_RS04905	COG2390	Transcriptional regulator
LacP0747_RS04945	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
LacP0747_RS04955	COG0557	exoribonuclease II activity
LacP0747_RS04965	COG1609	Transcriptional regulator
LacP0747_RS04970	COG0366	Alpha amylase catalytic
LacP0747_RS04985	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
LacP0747_RS05015	COG0395	ABC-type sugar transport system, permease component
LacP0747_RS05020	COG1175	transmembrane transport
LacP0747_RS05040	COG0561	phosphatase activity
LacP0747_RS05050	COG0280	phosphate acetyltransferase
LacP0747_RS05055	COG0802	atpase or kinase
LacP0747_RS05060	COG4152	abc transporter atp-binding protein
LacP0747_RS05065	COG1668	transmembrane transport
LacP0747_RS05075	COG0708	Exodeoxyribonuclease III
LacP0747_RS05090	COG3800	Transcriptional regulator
LacP0747_RS05090	COG1396	sequence-specific DNA binding
LacP0747_RS05100	COG1176	ABC-type spermidine putrescine transport system, permease component I
LacP0747_RS05105	COG1177	transmembrane transport
LacP0747_RS05110	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
LacP0747_RS05125	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
LacP0747_RS05130	COG1309	transcriptional regulator
LacP0747_RS05160	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
LacP0747_RS05185	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
LacP0747_RS05190	COG1459	type II secretion system
LacP0747_RS05220	COG0827	DNA restriction-modification system
LacP0747_RS05230	COG1113	amino acid transport
LacP0747_RS05340	COG4695	Portal protein
LacP0747_RS05365	COG2261	transglycosylase associated protein
LacP0747_RS05380	COG0745	RESPONSE REGULATOR receiver
LacP0747_RS05385	COG5002	protein histidine kinase activity
LacP0747_RS05385	COG3850	Histidine kinase
LacP0747_RS05415	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
LacP0747_RS05475	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
LacP0747_RS05480	COG2814	Major facilitator Superfamily
LacP0747_RS05485	COG0561	phosphatase activity
LacP0747_RS05490	COG2326	polyphosphate kinase activity
LacP0747_RS05495	COG3590	peptidase
LacP0747_RS05500	COG2814	Major facilitator Superfamily
LacP0747_RS05540	COG0673	inositol 2-dehydrogenase activity
LacP0747_RS05550	COG1447	Phosphotransferase system cellobiose-specific component IIA
LacP0747_RS05570	COG0514	ATP-dependent DNA helicase (RecQ)
LacP0747_RS05575	COG2309	aminopeptidase activity
LacP0747_RS05590	COG1295	ribonuclease BN
LacP0747_RS05595	COG0716	FMN binding
LacP0747_RS05600	COG0024	Methionine aminopeptidase
LacP0747_RS05605	COG0463	Glycosyl transferase, family 2
LacP0747_RS05625	COG1210	Utp--glucose-1-phosphate uridylyltransferase
LacP0747_RS05670	COG2190	(PTS) system
LacP0747_RS05670	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LacP0747_RS05670	COG1263	PTS System
LacP0747_RS05675	COG3711	transcriptional antiterminator
LacP0747_RS05680	COG4485	Bacterial membrane protein, YfhO
LacP0747_RS05690	COG0463	Glycosyl transferase, family 2
LacP0747_RS05700	COG4129	membrane
LacP0747_RS05710	COG1278	Cold shock
LacP0747_RS05720	COG1705	Flagellar rod assembly protein muramidase FlgJ
LacP0747_RS05735	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
LacP0747_RS05740	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
LacP0747_RS05755	COG1368	sulfuric ester hydrolase activity
LacP0747_RS05765	COG4975	Glucose uptake
LacP0747_RS05775	COG0582	viral genome integration into host DNA
LacP0747_RS05805	COG1396	sequence-specific DNA binding
LacP0747_RS05860	COG3935	DnaD domain protein
LacP0747_RS05865	COG0629	single-stranded DNA binding
LacP0747_RS06145	COG0590	tRNA wobble adenosine to inosine editing
LacP0747_RS06170	COG2814	Major facilitator Superfamily
LacP0747_RS06175	COG3548	integral membrane protein
LacP0747_RS06225	COG2514	catechol 2,3-dioxygenase activity
LacP0747_RS06240	COG2801	Transposase and inactivated derivatives
LacP0747_RS06245	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
LacP0747_RS06250	COG1435	thymidine kinase activity
LacP0747_RS06260	COG2890	protein-(glutamine-N5) methyltransferase activity
LacP0747_RS06265	COG0009	L-threonylcarbamoyladenylate synthase
LacP0747_RS06280	COG0356	it plays a direct role in the translocation of protons across the membrane
LacP0747_RS06325	COG1077	Cell shape determining protein MreB Mrl
LacP0747_RS06345	COG0772	Belongs to the SEDS family
LacP0747_RS06350	COG0509	glycine decarboxylation via glycine cleavage system
LacP0747_RS06355	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
LacP0747_RS06360	COG1464	Belongs to the NlpA lipoprotein family
LacP0747_RS06365	COG1464	Belongs to the NlpA lipoprotein family
LacP0747_RS06375	COG2011	ABC-type metal ion transport system permease component
LacP0747_RS06385	COG0719	Fe-S assembly protein
LacP0747_RS06390	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
LacP0747_RS06395	COG0822	iron-sulfur transferase activity
LacP0747_RS06400	COG0719	Fe-S assembly protein
LacP0747_RS06430	COG0589	response to stress
LacP0747_RS06440	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
LacP0747_RS06445	COG2918	glutathione biosynthetic process
LacP0747_RS06445	COG0189	ligase activity
LacP0747_RS06450	COG5506	Protein of unknown function (DUF1694)
LacP0747_RS06460	COG1760	l-serine dehydratase
LacP0747_RS06465	COG1760	l-serine dehydratase
LacP0747_RS06480	COG1028	Short-chain dehydrogenase reductase Sdr
LacP0747_RS06490	COG1428	Deoxynucleoside kinase
LacP0747_RS06500	COG4166	transmembrane transport
LacP0747_RS06505	COG2205	protein histidine kinase activity
LacP0747_RS06510	COG0745	RESPONSE REGULATOR receiver
LacP0747_RS06525	COG0583	DNA-binding transcription factor activity
LacP0747_RS06560	COG0454	-acetyltransferase
LacP0747_RS06575	COG1307	EDD domain protein, DegV family
LacP0747_RS06580	COG2197	response regulator
LacP0747_RS06585	COG4585	Histidine kinase
LacP0747_RS06595	COG1131	(ABC) transporter
LacP0747_RS06605	COG0789	Transcriptional regulator
LacP0747_RS06645	COG2183	response to ionizing radiation
LacP0747_RS06650	COG3620	sequence-specific DNA binding
LacP0747_RS06675	COG1956	GAF domain-containing protein
LacP0747_RS06680	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
LacP0747_RS06685	COG1104	cysteine desulfurase activity
LacP0747_RS06700	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
LacP0747_RS06705	COG0525	valine-tRNA ligase activity
LacP0747_RS06720	COG2003	Belongs to the UPF0758 family
LacP0747_RS06725	COG1077	Cell shape determining protein MreB Mrl
LacP0747_RS06730	COG1792	Involved in formation and maintenance of cell shape
LacP0747_RS06740	COG0850	regulation of cytokinetic process
LacP0747_RS06745	COG2894	cell division
LacP0747_RS06750	COG0765	amino acid transport
LacP0747_RS06760	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LacP0747_RS06765	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LacP0747_RS06780	COG2001	Belongs to the MraZ family
LacP0747_RS06795	COG0768	penicillin binding
LacP0747_RS06825	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
LacP0747_RS06845	COG3599	regulation of cell shape
LacP0747_RS06855	COG1278	Cold shock
LacP0747_RS06865	COG2814	Major facilitator Superfamily
LacP0747_RS06870	COG3853	Toxic anion resistance protein (TelA)
LacP0747_RS06880	COG0494	nUDIX hydrolase
LacP0747_RS06895	COG1104	cysteine desulfurase activity
LacP0747_RS06905	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
LacP0747_RS06925	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
LacP0747_RS06935	COG1597	lipid kinase activity
LacP0747_RS07000	COG0483	inositol monophosphate 1-phosphatase activity
LacP0747_RS07005	COG1217	gtp-binding protein TYPA
LacP0747_RS07010	COG0772	Belongs to the SEDS family
LacP0747_RS07015	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
LacP0747_RS07020	COG4471	UPF0298 protein
LacP0747_RS07025	COG0742	ribosomal rna small subunit methyltransferase
LacP0747_RS07035	COG3480	Lon protease (S16) C-terminal proteolytic domain
LacP0747_RS07045	COG2333	competence protein COMEC
LacP0747_RS07045	COG0658	competence protein
LacP0747_RS07050	COG1466	dna polymerase III delta subunit
LacP0747_RS07090	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
LacP0747_RS07105	COG1132	(ABC) transporter
LacP0747_RS07115	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
LacP0747_RS07135	COG0765	amino acid transport
LacP0747_RS07140	COG1126	abc transporter atp-binding protein
LacP0747_RS07150	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
LacP0747_RS07150	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LacP0747_RS07150	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LacP0747_RS07155	COG1105	Belongs to the carbohydrate kinase PfkB family
LacP0747_RS07160	COG1349	DNA-binding transcription factor activity
LacP0747_RS07170	COG2755	lipolytic protein G-D-S-L family
LacP0747_RS07170	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
LacP0747_RS07180	COG0300	oxidoreductase activity
LacP0747_RS07190	COG0542	response to heat
LacP0747_RS07205	COG0737	Belongs to the 5'-nucleotidase family
LacP0747_RS07220	COG0587	DNA-directed DNA polymerase activity
LacP0747_RS07240	COG2996	Protein conserved in bacteria
LacP0747_RS07250	COG0456	acetyltransferase
LacP0747_RS07255	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
LacP0747_RS07260	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
LacP0747_RS07265	COG1187	pseudouridine synthase activity
LacP0747_RS07270	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
LacP0747_RS07285	COG0514	ATP-dependent DNA helicase (RecQ)
LacP0747_RS07300	COG0539	negative regulation of cytoplasmic translation
LacP0747_RS07315	COG0457	Tetratricopeptide repeat
LacP0747_RS07320	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
LacP0747_RS07335	COG0488	(ABC) transporter
LacP0747_RS07350	COG1272	protein, Hemolysin III
LacP0747_RS07355	COG1307	EDD domain protein, DegV family
LacP0747_RS07360	COG2755	lipolytic protein G-D-S-L family
LacP0747_RS07370	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
LacP0747_RS07380	COG3409	Peptidoglycan-binding domain 1 protein
LacP0747_RS07380	COG0793	Belongs to the peptidase S41A family
LacP0747_RS07440	COG0758	DNA mediated transformation
LacP0747_RS07445	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
LacP0747_RS07465	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
LacP0747_RS07480	COG0187	DNA topoisomerase II activity
LacP0747_RS07485	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
LacP0747_RS07490	COG1882	Formate acetyltransferase
LacP0747_RS07495	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
LacP0747_RS07500	COG0583	DNA-binding transcription factor activity
LacP0747_RS07505	COG1227	inorganic diphosphatase activity
LacP0747_RS07510	COG4974	Belongs to the 'phage' integrase family
LacP0747_RS07520	COG0577	efflux transmembrane transporter activity
LacP0747_RS07525	COG1136	(ABC) transporter
LacP0747_RS07530	COG5002	protein histidine kinase activity
LacP0747_RS07535	COG0745	RESPONSE REGULATOR receiver
LacP0747_RS07555	COG0778	Nitroreductase
LacP0747_RS07560	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
LacP0747_RS07595	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
LacP0747_RS07610	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
LacP0747_RS07615	COG0494	nUDIX hydrolase
LacP0747_RS07620	COG1307	EDD domain protein, DegV family
LacP0747_RS07625	COG1293	RNA-binding protein homologous to eukaryotic snRNP
LacP0747_RS07640	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
LacP0747_RS07645	COG0508	dehydrogenase complex catalyzes the overall conversion of
LacP0747_RS07650	COG0022	dehydrogenase e1 component
LacP0747_RS07655	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
LacP0747_RS07660	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LacP0747_RS07665	COG3426	butyrate kinase activity
LacP0747_RS07670	COG0280	phosphate acetyltransferase
LacP0747_RS07675	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
LacP0747_RS07680	COG0284	orotidine-5'-phosphate decarboxylase activity
LacP0747_RS07695	COG0505	Belongs to the CarA family
LacP0747_RS07700	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
LacP0747_RS07710	COG2233	PERMEase
LacP0747_RS07715	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
LacP0747_RS07720	COG0564	pseudouridine synthase activity
LacP0747_RS07725	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
LacP0747_RS07740	COG0328	RNA-DNA hybrid ribonuclease activity
LacP0747_RS07750	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LacP0747_RS07765	COG1393	Belongs to the ArsC family
LacP0747_RS07770	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LacP0747_RS07775	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LacP0747_RS07780	COG0583	DNA-binding transcription factor activity
LacP0747_RS07785	COG3590	peptidase
LacP0747_RS07790	COG0095	Lipoate-protein ligase
LacP0747_RS07805	COG0116	Belongs to the methyltransferase superfamily
LacP0747_RS07830	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
LacP0747_RS07835	COG2131	deaminase
LacP0747_RS07840	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
LacP0747_RS07855	COG0436	Aminotransferase
LacP0747_RS07865	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
LacP0747_RS07865	COG1199	ATP-dependent helicase activity
LacP0747_RS07900	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
LacP0747_RS07900	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
LacP0747_RS07915	COG2151	metal-sulfur cluster biosynthetic enzyme
LacP0747_RS07920	COG1942	4-Oxalocrotonate Tautomerase
LacP0747_RS07925	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
LacP0747_RS07930	COG2384	SAM-dependent methyltransferase
LacP0747_RS07935	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
LacP0747_RS07940	COG0358	DNA primase activity
LacP0747_RS07965	COG1381	Involved in DNA repair and RecF pathway recombination
LacP0747_RS07975	COG0295	cytidine deaminase activity
LacP0747_RS07990	COG1702	phosphate starvation-inducible protein PhoH
LacP0747_RS07995	COG1610	YqeY-like protein
LacP0747_RS08010	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
LacP0747_RS08015	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
LacP0747_RS08020	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
LacP0747_RS08050	COG1131	(ABC) transporter
LacP0747_RS08060	COG3103	Sh3 type 3 domain protein
LacP0747_RS08060	COG0860	N-Acetylmuramoyl-L-alanine amidase
LacP0747_RS08060	COG4991	sh3 domain protein
LacP0747_RS08075	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
LacP0747_RS08085	COG1385	rRNA (uridine-N3-)-methyltransferase activity
LacP0747_RS08100	COG2094	Belongs to the DNA glycosylase MPG family
LacP0747_RS08135	COG0673	inositol 2-dehydrogenase activity
LacP0747_RS08140	COG0438	transferase activity, transferring glycosyl groups
LacP0747_RS08205	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
LacP0747_RS08215	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
LacP0747_RS08215	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
LacP0747_RS08245	COG1132	(ABC) transporter
LacP0747_RS08260	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
LacP0747_RS08270	COG0635	Involved in the biosynthesis of porphyrin-containing compound
LacP0747_RS08275	COG0196	riboflavin kinase activity
LacP0747_RS08285	COG0861	Integral membrane protein TerC family
LacP0747_RS08305	COG2740	Nucleic-acid-binding protein implicated in transcription termination
LacP0747_RS08310	COG0195	Participates in both transcription termination and antitermination
LacP0747_RS08330	COG0750	zinc metalloprotease
LacP0747_RS08335	COG4589	Belongs to the CDS family
LacP0747_RS08340	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
LacP0747_RS08370	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
LacP0747_RS08375	COG0204	Acyl-transferase
LacP0747_RS08380	COG0531	amino acid
LacP0747_RS08390	COG1132	(ABC) transporter
LacP0747_RS08395	COG1132	(ABC) transporter
LacP0747_RS08400	COG3763	UPF0154 protein
LacP0747_RS08405	COG4224	UPF0291 protein
LacP0747_RS08430	COG1837	Belongs to the UPF0109 family
LacP0747_RS08440	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
LacP0747_RS08455	COG0552	protein localization to endoplasmic reticulum
LacP0747_RS08460	COG1196	nuclear chromosome segregation
LacP0747_RS08465	COG0571	ribonuclease III activity
LacP0747_RS08475	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LacP0747_RS08480	COG0601	transmembrane transport
LacP0747_RS08485	COG4608	Belongs to the ABC transporter superfamily
LacP0747_RS08495	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LacP0747_RS08505	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
LacP0747_RS08510	COG1461	Dihydroxyacetone kinase
LacP0747_RS08525	COG1564	THIamine pyrophosphokinase
LacP0747_RS08530	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
LacP0747_RS08535	COG1162	GTPase activity
LacP0747_RS08540	COG0515	serine threonine protein kinase
LacP0747_RS08540	COG2815	serine threonine protein kinase
LacP0747_RS08550	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
LacP0747_RS08550	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
LacP0747_RS08560	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
LacP0747_RS08565	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
LacP0747_RS08575	COG0194	GDP metabolic process
LacP0747_RS08590	COG0497	DNA recombination
LacP0747_RS08595	COG1438	arginine binding
LacP0747_RS08600	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
LacP0747_RS08605	COG0142	geranyltranstransferase activity
LacP0747_RS08610	COG1722	exodeoxyribonuclease VII activity
LacP0747_RS08630	COG1302	Protein conserved in bacteria
LacP0747_RS08635	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
LacP0747_RS08640	COG0006	proline dipeptidase activity
LacP0747_RS08645	COG0211	Belongs to the bacterial ribosomal protein bL27 family
LacP0747_RS08650	COG2868	ribosomal protein
LacP0747_RS08655	COG0261	This protein binds to 23S rRNA in the presence of protein L20
LacP0747_RS08685	COG0789	Transcriptional regulator
LacP0747_RS08690	COG1982	Orn Lys Arg decarboxylase major
LacP0747_RS08695	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
LacP0747_RS08710	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
LacP0747_RS08715	COG1940	carbohydrate kinase activity
LacP0747_RS08725	COG0457	Tetratricopeptide repeat
LacP0747_RS08725	COG0705	Rhomboid family
LacP0747_RS08730	COG0768	penicillin binding
LacP0747_RS08740	COG4841	protein insertion into membrane
LacP0747_RS08745	COG2197	response regulator
LacP0747_RS08760	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
LacP0747_RS08765	COG0572	uridine kinase
LacP0747_RS08770	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
LacP0747_RS08775	COG0072	phenylalanine-tRNA ligase activity
LacP0747_RS08785	COG1733	regulation of RNA biosynthetic process
LacP0747_RS08795	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LacP0747_RS08805	COG0706	membrane insertase activity
LacP0747_RS08810	COG5002	protein histidine kinase activity
LacP0747_RS08815	COG0745	RESPONSE REGULATOR receiver
LacP0747_RS08820	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
LacP0747_RS08840	COG2226	methyltransferase
LacP0747_RS08845	COG0799	negative regulation of ribosome biogenesis
LacP0747_RS08855	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
LacP0747_RS08860	COG1534	Rna-binding protein
LacP0747_RS08865	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
LacP0747_RS08870	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
LacP0747_RS08875	COG0346	lactoylglutathione lyase activity
LacP0747_RS08885	COG0400	carboxylic ester hydrolase activity
LacP0747_RS08910	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
LacP0747_RS08940	COG1484	DNA-dependent DNA replication
LacP0747_RS08945	COG3611	Membrane attachment protein
LacP0747_RS08955	COG0237	dephospho-CoA kinase activity
LacP0747_RS08960	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
LacP0747_RS08965	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
LacP0747_RS08965	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
LacP0747_RS08970	COG0670	Belongs to the BI1 family
LacP0747_RS08980	COG1674	ftsk spoiiie
LacP0747_RS08985	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LacP0747_RS08990	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LacP0747_RS09015	COG1131	(ABC) transporter
LacP0747_RS09020	COG0537	adenosine 5'-monophosphoramidase activity
LacP0747_RS09030	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
LacP0747_RS09045	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
LacP0747_RS09050	COG0564	pseudouridine synthase activity
LacP0747_RS09055	COG1438	arginine binding
LacP0747_RS09060	COG0018	arginyl-trna synthetase
LacP0747_RS09080	COG0167	dihydroorotate dehydrogenase activity
LacP0747_RS09095	COG1393	Belongs to the ArsC family
LacP0747_RS09100	COG1234	tRNA 3'-trailer cleavage
LacP0747_RS09115	COG1136	(ABC) transporter
LacP0747_RS09120	COG0745	RESPONSE REGULATOR receiver
LacP0747_RS09125	COG0642	Histidine kinase
LacP0747_RS09135	COG2217	Heavy metal translocating P-type atpase
LacP0747_RS09140	COG3682	Transcriptional regulator
LacP0747_RS09150	COG0151	Belongs to the GarS family
LacP0747_RS09160	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
LacP0747_RS09165	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
LacP0747_RS09185	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
LacP0747_RS09195	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
LacP0747_RS09200	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
LacP0747_RS09210	COG2814	Major facilitator Superfamily
LacP0747_RS09220	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
LacP0747_RS09230	COG0542	response to heat
LacP0747_RS09245	COG1253	flavin adenine dinucleotide binding
LacP0747_RS09250	COG0628	permease
LacP0747_RS09265	COG3557	Belongs to the UPF0374 family
LacP0747_RS09285	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
LacP0747_RS09295	COG2188	Transcriptional regulator
LacP0747_RS09300	COG2723	6-phospho-beta-galactosidase activity
LacP0747_RS09305	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
LacP0747_RS09315	COG1447	Phosphotransferase system cellobiose-specific component IIA
LacP0747_RS09320	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
LacP0747_RS09325	COG0028	Belongs to the TPP enzyme family
LacP0747_RS09330	COG3425	synthase
LacP0747_RS09340	COG0183	Belongs to the thiolase family
LacP0747_RS09365	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
LacP0747_RS09385	COG3091	SprT-like family
LacP0747_RS09390	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
LacP0747_RS09395	COG4120	Belongs to the binding-protein-dependent transport system permease family
LacP0747_RS09430	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
LacP0747_RS09435	COG2188	Transcriptional regulator
LacP0747_RS09440	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
LacP0747_RS09445	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
LacP0747_RS09450	COG1506	peptidase
LacP0747_RS09450	COG0823	Involved in the tonB-independent uptake of proteins
LacP0747_RS09450	COG4946	Tricorn protease homolog
LacP0747_RS09465	COG3104	oligopeptide transport
LacP0747_RS09470	COG1136	(ABC) transporter
LacP0747_RS09470	COG0577	efflux transmembrane transporter activity
LacP0747_RS09595	COG0833	amino acid
LacP0747_RS09610	COG0028	Belongs to the TPP enzyme family
LacP0747_RS09620	COG0519	Catalyzes the synthesis of GMP from XMP
LacP0747_RS09645	COG0564	pseudouridine synthase activity
LacP0747_RS09665	COG3697	Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase
LacP0747_RS09665	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
LacP0747_RS09680	COG3697	Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase
LacP0747_RS09680	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
LacP0747_RS09715	COG0511	ligase activity, forming carbon-carbon bonds
LacP0747_RS09725	COG2851	Citrate transporter
LacP0747_RS09765	COG1131	(ABC) transporter
LacP0747_RS09780	COG2814	Major facilitator Superfamily
LacP0747_RS09800	COG1725	Transcriptional regulator
LacP0747_RS09805	COG1131	(ABC) transporter
LacP0747_RS09820	COG1136	(ABC) transporter
LacP0747_RS09830	COG4608	Belongs to the ABC transporter superfamily
LacP0747_RS09835	COG0444	Belongs to the ABC transporter superfamily
LacP0747_RS09845	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LacP0747_RS09850	COG0601	transmembrane transport
LacP0747_RS09855	COG4166	transmembrane transport
LacP0747_RS09865	COG0640	Transcriptional regulator
LacP0747_RS09900	COG5549	protein import
LacP0747_RS09900	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LacP0747_RS09910	COG1349	DNA-binding transcription factor activity
LacP0747_RS09985	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
LacP0747_RS09990	COG1061	Type III restriction enzyme res subunit
LacP0747_RS09995	COG1002	Type II restriction enzyme, methylase subunits
LacP0747_RS10025	COG4690	dipeptidase activity
LacP0747_RS10030	COG1607	acyl-coa hydrolase
LacP0747_RS10035	COG3973	AAA domain
LacP0747_RS10045	COG0475	glutathione-regulated potassium exporter activity
LacP0747_RS10045	COG0569	domain protein
LacP0747_RS10050	COG2267	carboxylic ester hydrolase activity
LacP0747_RS10080	COG1136	(ABC) transporter
LacP0747_RS10085	COG0531	amino acid
LacP0747_RS10090	COG1597	lipid kinase activity
LacP0747_RS10095	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
LacP0747_RS10100	COG0726	polysaccharide deacetylase
LacP0747_RS10115	COG0489	protein tyrosine kinase activity
LacP0747_RS10135	COG0463	Glycosyl transferase, family 2
LacP0747_RS10165	COG0463	Glycosyl transferase, family 2
LacP0747_RS10170	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
LacP0747_RS10180	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
LacP0747_RS10200	COG0765	amino acid transport
LacP0747_RS10205	COG0765	amino acid transport
LacP0747_RS10210	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LacP0747_RS10230	COG0735	belongs to the Fur family
LacP0747_RS10240	COG0194	GDP metabolic process
LacP0747_RS10245	COG0456	acetyltransferase
LacP0747_RS10245	COG0454	-acetyltransferase
LacP0747_RS10265	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
LacP0747_RS10290	COG0058	SHG alpha-glucan phosphorylase activity
LacP0747_RS10300	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
LacP0747_RS10310	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
LacP0747_RS10315	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
LacP0747_RS10325	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
LacP0747_RS10335	COG1393	Belongs to the ArsC family
LacP0747_RS10350	COG1091	dTDP-4-dehydrorhamnose reductase activity
LacP0747_RS10355	COG1088	dTDP-glucose 4,6-dehydratase activity
LacP0747_RS10365	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
LacP0747_RS10370	COG4464	protein tyrosine phosphatase activity
LacP0747_RS10375	COG1316	TRANSCRIPTIONal
LacP0747_RS10385	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
LacP0747_RS10395	COG0438	transferase activity, transferring glycosyl groups
LacP0747_RS10410	COG0438	transferase activity, transferring glycosyl groups
LacP0747_RS10435	COG0489	protein tyrosine kinase activity
LacP0747_RS10450	COG4708	membrane
LacP0747_RS10455	COG1028	Short-chain dehydrogenase reductase Sdr
LacP0747_RS10475	COG4608	Belongs to the ABC transporter superfamily
LacP0747_RS10480	COG0444	Belongs to the ABC transporter superfamily
LacP0747_RS10485	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LacP0747_RS10490	COG0601	transmembrane transport
LacP0747_RS10495	COG4166	transmembrane transport
LacP0747_RS10500	COG2814	Major facilitator Superfamily
LacP0747_RS10505	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
LacP0747_RS10510	COG1556	Lactate utilization protein
LacP0747_RS10515	COG1139	Iron-sulfur cluster binding protein
LacP0747_RS10530	COG1447	Phosphotransferase system cellobiose-specific component IIA
LacP0747_RS10550	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
LacP0747_RS10585	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LacP0747_RS10675	COG1263	PTS System
LacP0747_RS10675	COG2190	(PTS) system
LacP0747_RS10675	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LacP0747_RS10680	COG0366	Alpha amylase catalytic
LacP0747_RS10685	COG1609	Transcriptional regulator
LacP0747_RS10695	COG0702	epimerase
LacP0747_RS10700	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
LacP0747_RS10720	COG0439	Biotin carboxylase
LacP0747_RS10730	COG0511	ligase activity, forming carbon-carbon bonds
LacP0747_RS10735	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
LacP0747_RS10740	COG1028	Short-chain dehydrogenase reductase Sdr
LacP0747_RS10755	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LacP0747_RS10760	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
LacP0747_RS10770	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
LacP0747_RS10775	COG2267	carboxylic ester hydrolase activity
LacP0747_RS10780	COG1979	alcohol dehydrogenase
LacP0747_RS10810	COG1846	Transcriptional regulator
LacP0747_RS10820	COG0494	nUDIX hydrolase
LacP0747_RS10825	COG0588	phosphoglycerate mutase activity
LacP0747_RS10845	COG0628	permease
LacP0747_RS10860	COG1597	lipid kinase activity
LacP0747_RS10865	COG0028	Belongs to the TPP enzyme family
LacP0747_RS10910	COG0460	homoserine dehydrogenase
LacP0747_RS10915	COG0527	aspartate kinase activity
LacP0747_RS10920	COG2268	Band 7 protein
LacP0747_RS10935	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LacP0747_RS10940	COG0436	Aminotransferase
LacP0747_RS10960	COG0367	asparagine synthase
LacP0747_RS10985	COG0142	geranyltranstransferase activity
LacP0747_RS10995	COG4152	abc transporter atp-binding protein
LacP0747_RS11010	COG1131	(ABC) transporter
LacP0747_RS11035	COG1297	OPT oligopeptide transporter protein
LacP0747_RS11055	COG0477	Major facilitator Superfamily
LacP0747_RS11065	COG2723	6-phospho-beta-galactosidase activity
LacP0747_RS11070	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LacP0747_RS11070	COG1263	PTS System
LacP0747_RS11070	COG2190	(PTS) system
LacP0747_RS11080	COG1132	(ABC) transporter
LacP0747_RS11085	COG1132	(ABC) transporter
LacP0747_RS11110	COG1518	maintenance of DNA repeat elements
LacP0747_RS11115	COG3513	CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
LacP0747_RS11140	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
LacP0747_RS11145	COG4988	ABC transporter
LacP0747_RS11150	COG1294	oxidase, subunit
LacP0747_RS11155	COG1271	oxidase subunit
LacP0747_RS11185	COG0697	spore germination
LacP0747_RS11190	COG2818	Glycosylase
LacP0747_RS11205	COG2365	Tyrosine phosphatase family
LacP0747_RS11210	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
LacP0747_RS11220	COG1268	BioY protein
LacP0747_RS11225	COG0789	Transcriptional regulator
LacP0747_RS11235	COG1063	alcohol dehydrogenase
LacP0747_RS11255	COG2264	protein methyltransferase activity
LacP0747_RS11265	COG0505	Belongs to the CarA family
LacP0747_RS11275	COG1253	flavin adenine dinucleotide binding
LacP0747_RS11280	COG2814	Major facilitator Superfamily
LacP0747_RS11305	COG0531	amino acid
LacP0747_RS11325	COG1266	CAAX protease self-immunity
LacP0747_RS11330	COG1316	TRANSCRIPTIONal
LacP0747_RS11340	COG1131	(ABC) transporter
LacP0747_RS11345	COG1725	Transcriptional regulator
LacP0747_RS11350	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
LacP0747_RS11355	COG0488	(ABC) transporter
LacP0747_RS11365	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
LacP0747_RS11375	COG0456	acetyltransferase
LacP0747_RS11375	COG1214	PFAM Peptidase M22, glycoprotease
LacP0747_RS11380	COG1214	PFAM Peptidase M22, glycoprotease
LacP0747_RS11420	COG0470	DNA polymerase III
LacP0747_RS11425	COG3870	Protein conserved in bacteria
LacP0747_RS11450	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
LacP0747_RS11460	COG0590	tRNA wobble adenosine to inosine editing
LacP0747_RS11470	COG2813	Specifically methylates the guanine in position
LacP0747_RS11475	COG0392	lysyltransferase activity
LacP0747_RS11475	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
LacP0747_RS11485	COG1609	Transcriptional regulator
LacP0747_RS11530	COG0477	Major facilitator Superfamily
LacP0747_RS11535	COG1012	belongs to the aldehyde dehydrogenase family
LacP0747_RS11550	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
LacP0747_RS11560	COG5646	InterPro IPR014922
LacP0747_RS11565	COG2096	Adenosyltransferase
LacP0747_RS11595	COG0250	Participates in transcription elongation, termination and antitermination
LacP0747_RS11625	COG4939	FMN-binding domain protein
LacP0747_RS11665	COG1131	(ABC) transporter
LacP0747_RS11690	COG3688	RNA-binding protein containing a PIN domain
LacP0747_RS11695	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LacP0747_RS11700	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
LacP0747_RS11710	COG0277	FAD linked oxidase domain protein
LacP0747_RS11735	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
LacP0747_RS11740	COG1737	Transcriptional regulator
LacP0747_RS11745	COG4377	Putative membrane peptidase family (DUF2324)
LacP0747_RS11760	COG4932	domain protein
LacP0747_RS11760	COG4886	Leucine-rich repeat (LRR) protein
LacP0747_RS11795	COG4956	integral membrane protein (PIN domain superfamily)
LacP0747_RS11800	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
LacP0747_RS11805	COG0756	dUTP diphosphatase activity
LacP0747_RS11810	COG2388	GCN5-related N-acetyl-transferase
LacP0747_RS11850	COG1131	(ABC) transporter
LacP0747_RS11860	COG0574	Belongs to the PEP-utilizing enzyme family
LacP0747_RS11860	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
LacP0747_RS11865	COG0517	IMP dehydrogenase activity
LacP0747_RS11870	COG0588	phosphoglycerate mutase activity
LacP0747_RS11885	COG1304	FMN binding
LacP0747_RS11920	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
LacP0747_RS11940	COG3764	Sortase (surface protein transpeptidase)
LacP0747_RS11980	COG1695	Transcriptional regulator
LacP0747_RS12025	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LacP0747_RS12030	COG2274	protein secretion by the type I secretion system
LacP0747_RS12095	COG0110	maltose O-acetyltransferase activity
LacP0747_RS12115	COG4989	oxidoreductase activity
LacP0747_RS12120	COG4221	oxidoreductase activity
LacP0747_RS12125	COG1902	pentaerythritol trinitrate reductase activity
LacP0747_RS12130	COG0114	fumarate hydratase activity
LacP0747_RS12140	COG1914	H( )-stimulated, divalent metal cation uptake system
LacP0747_RS12145	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
LacP0747_RS12155	COG2814	Major facilitator Superfamily
LacP0747_RS12185	COG1108	ABC-type Mn2 Zn2 transport systems permease components
LacP0747_RS12190	COG1121	(ABC) transporter
LacP0747_RS12195	COG1012	belongs to the aldehyde dehydrogenase family
LacP0747_RS12285	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
LacP0747_RS12300	COG0148	phosphopyruvate hydratase activity
LacP0747_RS12305	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
LacP0747_RS12325	COG3639	organic phosphonate transmembrane transporter activity
LacP0747_RS12345	COG1116	anion transmembrane transporter activity
LacP0747_RS12350	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
LacP0747_RS12365	COG4555	ABC transporter
LacP0747_RS12405	COG0577	efflux transmembrane transporter activity
LacP0747_RS12410	COG1136	(ABC) transporter
LacP0747_RS12420	COG0789	Transcriptional regulator
LacP0747_RS12500	COG0200	Binds to the 23S rRNA
LacP0747_RS12610	COG0450	alkyl hydroperoxide reductase
LacP0747_RS12655	COG0542	response to heat
LacP0747_RS12660	COG4463	regulation of RNA biosynthetic process
LacP0747_RS12730	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
LacP0747_RS12735	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
LacP0747_RS12775	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
LacP0747_RS12780	COG0037	tRNA processing
LacP0747_RS12785	COG1098	S1 RNA binding domain
LacP0747_RS12795	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
LacP0747_RS12800	COG2244	polysaccharide biosynthetic process
LacP0747_RS12805	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
LacP0747_RS12815	COG0039	L-malate dehydrogenase activity
LacP0747_RS12830	COG1376	ErfK ybiS ycfS ynhG family protein
LacP0747_RS12835	COG0493	'glutamate synthase
LacP0747_RS12840	COG0069	glutamate synthase activity
LacP0747_RS12840	COG0067	glutamate synthase
LacP0747_RS12840	COG0070	glutamate synthase
LacP0747_RS12845	COG4708	membrane
LacP0747_RS12850	COG2337	Toxic component of a toxin-antitoxin (TA) module
LacP0747_RS12880	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
LacP0747_RS12915	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
LacP0747_RS12925	COG0504	CTP synthase activity
LacP0747_RS12945	COG0095	Lipoate-protein ligase
LacP0747_RS12950	COG1078	dGTPase activity
LacP0747_RS12980	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
LacP0747_RS12985	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
LacP0747_RS12995	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
LacP0747_RS13000	COG4619	ABC transporter
LacP0747_RS13005	COG0390	transport system, permease component
LacP0747_RS13015	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
LacP0747_RS13020	COG4466	Protein conserved in bacteria
LacP0747_RS13025	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
LacP0747_RS13030	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
LacP0747_RS13035	COG0084	hydrolase, TatD family'
LacP0747_RS13045	COG3684	Belongs to the aldolase LacD family
LacP0747_RS13060	COG3290	protein histidine kinase activity
LacP0747_RS13075	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LacP0747_RS13075	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LacP0747_RS13085	COG1801	Protein of unknown function DUF72
LacP0747_RS13105	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
LacP0747_RS13120	COG1881	PFAM PEBP family protein
LacP0747_RS13130	COG4086	secreted protein
LacP0747_RS13135	COG0248	Ppx GppA phosphatase
LacP0747_RS13140	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
LacP0747_RS13150	COG4989	oxidoreductase activity
LacP0747_RS13155	COG2226	methyltransferase
LacP0747_RS13165	COG0534	Mate efflux family protein
LacP0747_RS13170	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
LacP0747_RS13175	COG1704	LemA family
LacP0747_RS13185	COG0577	efflux transmembrane transporter activity
LacP0747_RS13185	COG1136	(ABC) transporter
LacP0747_RS13190	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LacP0747_RS13200	COG1174	glycine betaine transport
LacP0747_RS13205	COG3973	AAA domain
LacP0747_RS13230	COG1418	mRNA catabolic process
LacP0747_RS13240	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
LacP0747_RS13245	COG0667	Aldo Keto reductase
LacP0747_RS13250	COG0561	phosphatase activity
LacP0747_RS13270	COG0588	phosphoglycerate mutase activity
LacP0747_RS13275	COG0561	phosphatase activity
LacP0747_RS13290	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LacP0747_RS13295	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
LacP0747_RS13300	COG1811	Na channel or pump
LacP0747_RS13310	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LacP0747_RS13310	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
LacP0747_RS13310	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LacP0747_RS13315	COG1105	Belongs to the carbohydrate kinase PfkB family
LacP0747_RS13325	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
LacP0747_RS13345	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
LacP0747_RS13345	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LacP0747_RS13350	COG3715	PTS system
LacP0747_RS13355	COG3716	PTS system mannose fructose sorbose family IID component
LacP0747_RS13360	COG1447	Phosphotransferase system cellobiose-specific component IIA
LacP0747_RS13370	COG2723	6-phospho-beta-galactosidase activity
LacP0747_RS13375	COG1940	carbohydrate kinase activity
LacP0747_RS13390	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
LacP0747_RS13395	COG2188	Transcriptional regulator
LacP0747_RS13410	COG3775	system Galactitol-specific IIC component
LacP0747_RS13425	COG1349	DNA-binding transcription factor activity
LacP0747_RS13435	COG0366	Alpha amylase catalytic
LacP0747_RS13465	COG0463	Glycosyl transferase, family 2
LacP0747_RS13475	COG0586	Pfam SNARE associated Golgi protein
LacP0747_RS13480	COG0745	RESPONSE REGULATOR receiver
LacP0747_RS13490	COG1263	PTS System
LacP0747_RS13490	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LacP0747_RS13520	COG3711	transcriptional antiterminator
LacP0747_RS13530	COG2190	(PTS) system
LacP0747_RS13530	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LacP0747_RS13530	COG1263	PTS System
LacP0747_RS13570	COG3414	Phosphotransferase system galactitol-specific IIB component
LacP0747_RS13575	COG3775	system Galactitol-specific IIC component
LacP0747_RS13600	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
LacP0747_RS13615	COG2204	response regulator
LacP0747_RS13640	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
LacP0747_RS13645	COG0800	Aldolase
LacP0747_RS13665	COG3964	amidohydrolase
LacP0747_RS13710	COG3732	PTS system glucitol sorbitol-specific
LacP0747_RS13715	COG3730	PTS system glucitol sorbitol-specific
LacP0747_RS13725	COG3711	transcriptional antiterminator
LacP0747_RS13725	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
LacP0747_RS13735	COG2190	(PTS) system
LacP0747_RS13735	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LacP0747_RS13735	COG1263	PTS System
LacP0747_RS13745	COG2723	6-phospho-beta-galactosidase activity
LacP0747_RS13750	COG1609	Transcriptional regulator
LacP0747_RS13755	COG1263	PTS System
LacP0747_RS13755	COG2190	(PTS) system
LacP0747_RS13755	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LacP0747_RS13765	COG0561	phosphatase activity
LacP0747_RS13770	COG3623	hexulose-6-phosphate isomerase
LacP0747_RS13775	COG1349	DNA-binding transcription factor activity
LacP0747_RS13780	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
LacP0747_RS13800	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
LacP0747_RS13815	COG1063	alcohol dehydrogenase
LacP0747_RS13830	COG3716	PTS system mannose fructose sorbose family IID component
LacP0747_RS13835	COG3715	PTS system
LacP0747_RS13840	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LacP0747_RS13850	COG1063	alcohol dehydrogenase
LacP0747_RS13855	COG1349	DNA-binding transcription factor activity
LacP0747_RS13860	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
LacP0747_RS13870	COG1446	asparaginase
LacP0747_RS13875	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
LacP0747_RS13880	COG2188	Transcriptional regulator
LacP0747_RS13905	COG1070	Carbohydrate kinase
LacP0747_RS13910	COG1063	alcohol dehydrogenase
LacP0747_RS13915	COG3716	PTS system mannose fructose sorbose family IID component
LacP0747_RS13925	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LacP0747_RS13925	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
LacP0747_RS13935	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
LacP0747_RS13935	COG3711	transcriptional antiterminator
LacP0747_RS13945	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
LacP0747_RS13950	COG3775	system Galactitol-specific IIC component
LacP0747_RS13965	COG0191	fructose-bisphosphate aldolase activity
LacP0747_RS13970	COG2188	Transcriptional regulator
LacP0747_RS13985	COG0477	Major facilitator Superfamily
LacP0747_RS13990	COG0456	acetyltransferase
LacP0747_RS14025	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
LacP0747_RS14035	COG0395	ABC-type sugar transport system, permease component
LacP0747_RS14045	COG3842	ATPase activity
LacP0747_RS14050	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
LacP0747_RS14055	COG1335	isochorismatase
LacP0747_RS14070	COG4948	Mandelate Racemase Muconate Lactonizing
LacP0747_RS14080	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
LacP0747_RS14085	COG1737	Transcriptional regulator
LacP0747_RS14090	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LacP0747_RS14095	COG3716	PTS system mannose fructose sorbose family IID component
LacP0747_RS14110	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
LacP0747_RS14120	COG2076	Multidrug Resistance protein
LacP0747_RS14145	COG0604	alcohol dehydrogenase
LacP0747_RS14150	COG2365	Tyrosine phosphatase family
LacP0747_RS14160	COG0789	Transcriptional regulator
LacP0747_RS14165	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LacP0747_RS14190	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
LacP0747_RS14205	COG4166	transmembrane transport
LacP0747_RS14215	COG2217	Heavy metal translocating P-type atpase
LacP0747_RS14230	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LacP0747_RS14235	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
LacP0747_RS14250	COG5002	protein histidine kinase activity
LacP0747_RS14255	COG0745	RESPONSE REGULATOR receiver
LacP0747_RS14260	COG0596	Alpha beta hydrolase
LacP0747_RS14265	COG0765	amino acid transport
LacP0747_RS14290	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
LacP0747_RS14295	COG2188	Transcriptional regulator
LacP0747_RS14300	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
LacP0747_RS14305	COG1447	Phosphotransferase system cellobiose-specific component IIA
LacP0747_RS14325	COG1335	isochorismatase
LacP0747_RS14330	COG2814	Major facilitator Superfamily
LacP0747_RS14335	COG2807	transmembrane transport
LacP0747_RS14340	COG0667	Aldo Keto reductase
LacP0747_RS14350	COG3716	PTS system mannose fructose sorbose family IID component
LacP0747_RS14355	COG3715	PTS system
LacP0747_RS14390	COG0765	amino acid transport
LacP0747_RS14395	COG1126	abc transporter atp-binding protein
LacP0747_RS14435	COG4133	protoheme IX ABC transporter activity
LacP0747_RS14440	COG3001	Fructosamine kinase
LacP0747_RS14450	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LacP0747_RS14455	COG0765	amino acid transport
LacP0747_RS14470	COG0714	Associated with various cellular activities
LacP0747_RS14480	COG1305	Transglutaminase-like
LacP0747_RS14485	COG0438	transferase activity, transferring glycosyl groups
LacP0747_RS14490	COG0110	maltose O-acetyltransferase activity
LacP0747_RS14495	COG0561	phosphatase activity
LacP0747_RS14520	COG3493	citrate carrier protein
LacP0747_RS14525	COG3290	protein histidine kinase activity
LacP0747_RS14530	COG4565	transcriptional regulatory protein
LacP0747_RS14575	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LacP0747_RS14575	COG1263	PTS System
LacP0747_RS14580	COG2190	(PTS) system
LacP0747_RS14580	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LacP0747_RS14580	COG1263	PTS System
LacP0747_RS14585	COG3711	transcriptional antiterminator
LacP0747_RS14595	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
LacP0747_RS14615	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
LacP0747_RS14625	COG2213	PTS system mannitol-specific
LacP0747_RS14635	COG0561	phosphatase activity
LacP0747_RS14655	COG1136	(ABC) transporter
LacP0747_RS14655	COG0577	efflux transmembrane transporter activity
LacP0747_RS14660	COG0577	efflux transmembrane transporter activity
LacP0747_RS14670	COG2723	6-phospho-beta-galactosidase activity
LacP0747_RS14675	COG2190	(PTS) system
LacP0747_RS14675	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LacP0747_RS14675	COG1263	PTS System
LacP0747_RS14700	COG0371	Dehydrogenase
LacP0747_RS14705	COG1473	amidohydrolase
LacP0747_RS14740	COG0706	membrane insertase activity
LacP0747_RS14820	COG3843	relaxase mobilization nuclease domain protein
LacP0747_RS14840	COG0662	Cupin 2, conserved barrel domain protein
LacP0747_RS14845	COG2801	Transposase and inactivated derivatives
LacP0747_RS14880	COG2801	Transposase and inactivated derivatives
LacP0747_RS14895	COG2188	Transcriptional regulator
LacP0747_RS14900	COG2222	sugar isomerase
LacP0747_RS14910	COG2222	sugar isomerase
LacP0747_RS14915	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LacP0747_RS14920	COG3715	PTS system
LacP0747_RS14925	COG3716	PTS system mannose fructose sorbose family IID component
LacP0747_RS14940	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
LacP0747_RS14960	COG2190	(PTS) system
LacP0747_RS14960	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LacP0747_RS14960	COG1263	PTS System
LacP0747_RS14965	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
LacP0747_RS14970	COG0698	ribose 5-phosphate isomerase
LacP0747_RS14975	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LacP0747_RS14975	COG1263	PTS System
LacP0747_RS15005	COG1070	Carbohydrate kinase
LacP0747_RS15030	COG1879	ABC-type sugar transport system periplasmic component
LacP0747_RS15035	COG1830	Aldolase
LacP0747_RS15040	COG0561	phosphatase activity
LacP0747_RS15055	COG2826	transposase and inactivated derivatives, IS30 family
LacP0747_RS15070	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
LacP0747_RS15085	COG1192	Involved in chromosome partitioning
LacP0747_RS15145	COG0776	regulation of translation