locus-tag	class	description
LacP0761_RS00010	COG0592	DNA-directed DNA polymerase activity
LacP0761_RS00015	COG2501	S4 domain
LacP0761_RS00025	COG0187	DNA topoisomerase II activity
LacP0761_RS00035	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
LacP0761_RS00050	COG0629	single-stranded DNA binding
LacP0761_RS00060	COG1271	oxidase subunit
LacP0761_RS00065	COG1294	oxidase, subunit
LacP0761_RS00105	COG3942	CHAP domain
LacP0761_RS00125	COG0561	phosphatase activity
LacP0761_RS00145	COG3409	Peptidoglycan-binding domain 1 protein
LacP0761_RS00260	COG0800	Aldolase
LacP0761_RS00295	COG2814	Major facilitator Superfamily
LacP0761_RS00305	COG1033	growth of symbiont in host cell
LacP0761_RS00305	COG2409	Drug exporters of the RND superfamily
LacP0761_RS00310	COG1309	transcriptional regulator
LacP0761_RS00325	COG1732	Glycine betaine
LacP0761_RS00360	COG2217	Heavy metal translocating P-type atpase
LacP0761_RS00370	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
LacP0761_RS00375	COG0159	tryptophan synthase activity
LacP0761_RS00380	COG0133	tryptophan synthase activity
LacP0761_RS00385	COG0135	phosphoribosylanthranilate isomerase activity
LacP0761_RS00390	COG0134	indole-3-glycerol-phosphate synthase activity
LacP0761_RS00405	COG2814	Major facilitator Superfamily
LacP0761_RS00440	COG1131	(ABC) transporter
LacP0761_RS00465	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
LacP0761_RS00485	COG0019	diaminopimelate decarboxylase activity
LacP0761_RS00490	COG0527	aspartate kinase activity
LacP0761_RS00495	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
LacP0761_RS00500	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
LacP0761_RS00545	COG0305	Participates in initiation and elongation during chromosome replication
LacP0761_RS00560	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
LacP0761_RS00565	COG1737	Transcriptional regulator
LacP0761_RS00570	COG1309	transcriptional regulator
LacP0761_RS00575	COG1136	(ABC) transporter
LacP0761_RS00575	COG0577	efflux transmembrane transporter activity
LacP0761_RS00595	COG2217	Heavy metal translocating P-type atpase
LacP0761_RS00600	COG0640	Transcriptional regulator
LacP0761_RS00605	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
LacP0761_RS00610	COG0583	DNA-binding transcription factor activity
LacP0761_RS00615	COG1395	domain, Protein
LacP0761_RS00625	COG1131	(ABC) transporter
LacP0761_RS00635	COG1328	CTP reductase activity
LacP0761_RS00715	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
LacP0761_RS00750	COG2252	PERMEase
LacP0761_RS00765	COG1116	anion transmembrane transporter activity
LacP0761_RS00770	COG4521	taurine ABC transporter
LacP0761_RS00785	COG0446	pyridine nucleotide-disulphide oxidoreductase
LacP0761_RS00790	COG2391	methyltransferase activity
LacP0761_RS00805	COG0346	lactoylglutathione lyase activity
LacP0761_RS00865	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
LacP0761_RS00890	COG1511	domain protein
LacP0761_RS00890	COG1511	domain protein
LacP0761_RS00900	COG0477	Major facilitator Superfamily
LacP0761_RS00910	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
LacP0761_RS00915	COG4166	transmembrane transport
LacP0761_RS00935	COG1131	(ABC) transporter
LacP0761_RS00955	COG1132	(ABC) transporter
LacP0761_RS00960	COG1396	sequence-specific DNA binding
LacP0761_RS00970	COG0446	pyridine nucleotide-disulphide oxidoreductase
LacP0761_RS01010	COG0716	FMN binding
LacP0761_RS01025	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LacP0761_RS01035	COG2261	transglycosylase associated protein
LacP0761_RS01050	COG1302	Protein conserved in bacteria
LacP0761_RS01080	COG3442	glutamine amidotransferase
LacP0761_RS01100	COG1192	Involved in chromosome partitioning
LacP0761_RS01105	COG1475	DNA binding
LacP0761_RS01110	COG4481	Protein conserved in bacteria
LacP0761_RS01115	COG0012	GTP binding
LacP0761_RS01125	COG0516	GMP reductase activity
LacP0761_RS01125	COG0517	IMP dehydrogenase activity
LacP0761_RS01145	COG1686	Belongs to the peptidase S11 family
LacP0761_RS01150	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
LacP0761_RS01160	COG1794	racemase activity, acting on amino acids and derivatives
LacP0761_RS01165	COG0656	L-ascorbic acid biosynthetic process
LacP0761_RS01170	COG1349	DNA-binding transcription factor activity
LacP0761_RS01175	COG2814	Major facilitator Superfamily
LacP0761_RS01180	COG1012	belongs to the aldehyde dehydrogenase family
LacP0761_RS01185	COG3718	enzyme involved in inositol metabolism
LacP0761_RS01190	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LacP0761_RS01195	COG3962	Belongs to the TPP enzyme family
LacP0761_RS01200	COG0673	inositol 2-dehydrogenase activity
LacP0761_RS01205	COG0673	inositol 2-dehydrogenase activity
LacP0761_RS01215	COG0191	fructose-bisphosphate aldolase activity
LacP0761_RS01220	COG1942	4-Oxalocrotonate Tautomerase
LacP0761_RS01225	COG1737	Transcriptional regulator
LacP0761_RS01230	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
LacP0761_RS01240	COG2610	gluconate transmembrane transporter activity
LacP0761_RS01250	COG1121	(ABC) transporter
LacP0761_RS01265	COG2084	Dehydrogenase
LacP0761_RS01270	COG1164	Oligoendopeptidase f
LacP0761_RS01275	COG1316	TRANSCRIPTIONal
LacP0761_RS01280	COG1114	Component of the transport system for branched-chain amino acids
LacP0761_RS01295	COG1216	Glycosyl transferase, family 2
LacP0761_RS01320	COG0488	(ABC) transporter
LacP0761_RS01345	COG3118	belongs to the thioredoxin family
LacP0761_RS01360	COG0683	leucine binding
LacP0761_RS01390	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
LacP0761_RS01400	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
LacP0761_RS01405	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
LacP0761_RS01430	COG2723	6-phospho-beta-galactosidase activity
LacP0761_RS01435	COG0446	pyridine nucleotide-disulphide oxidoreductase
LacP0761_RS01455	COG2182	Extracellular solute-binding protein
LacP0761_RS01465	COG3064	Membrane
LacP0761_RS01465	COG3583	domain protein
LacP0761_RS01465	COG3525	Glycosyl hydrolase, family 20, catalytic domain
LacP0761_RS01470	COG1482	cell wall glycoprotein biosynthetic process
LacP0761_RS01475	COG2188	Transcriptional regulator
LacP0761_RS01480	COG2222	sugar isomerase
LacP0761_RS01485	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
LacP0761_RS01500	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LacP0761_RS01505	COG3715	PTS system
LacP0761_RS01510	COG3716	PTS system mannose fructose sorbose family IID component
LacP0761_RS01515	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LacP0761_RS01515	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
LacP0761_RS01525	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
LacP0761_RS01530	COG0006	proline dipeptidase activity
LacP0761_RS01535	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
LacP0761_RS01540	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
LacP0761_RS01545	COG1447	Phosphotransferase system cellobiose-specific component IIA
LacP0761_RS01550	COG1363	Peptidase, m42
LacP0761_RS01560	COG2195	Cleaves the N-terminal amino acid of tripeptides
LacP0761_RS01565	COG4166	transmembrane transport
LacP0761_RS01590	COG1129	ABC transporter
LacP0761_RS01600	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
LacP0761_RS01620	COG0351	phosphomethylpyrimidine kinase
LacP0761_RS01625	COG0531	amino acid
LacP0761_RS01635	COG1609	Transcriptional regulator
LacP0761_RS01650	COG1172	Belongs to the binding-protein-dependent transport system permease family
LacP0761_RS01655	COG1879	ABC-type sugar transport system periplasmic component
LacP0761_RS01675	COG2814	Major facilitator Superfamily
LacP0761_RS01715	COG1131	(ABC) transporter
LacP0761_RS01735	COG1053	succinate dehydrogenase
LacP0761_RS01740	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
LacP0761_RS01770	COG1378	Sugar-specific transcriptional regulator TrmB
LacP0761_RS01785	COG2267	carboxylic ester hydrolase activity
LacP0761_RS01820	COG1609	Transcriptional regulator
LacP0761_RS01830	COG3716	PTS system mannose fructose sorbose family IID component
LacP0761_RS01840	COG1262	PFAM Formylglycine-generating sulfatase enzyme
LacP0761_RS01850	COG0641	radical SAM
LacP0761_RS01860	COG3716	PTS system mannose fructose sorbose family IID component
LacP0761_RS01865	COG3715	PTS system
LacP0761_RS01870	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LacP0761_RS01900	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
LacP0761_RS01905	COG3711	transcriptional antiterminator
LacP0761_RS01910	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
LacP0761_RS01910	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
LacP0761_RS01920	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
LacP0761_RS01920	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LacP0761_RS01920	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LacP0761_RS01925	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LacP0761_RS01930	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LacP0761_RS01930	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
LacP0761_RS01930	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LacP0761_RS01950	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LacP0761_RS01950	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
LacP0761_RS01950	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LacP0761_RS01955	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LacP0761_RS01955	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LacP0761_RS01960	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
LacP0761_RS01975	COG0191	fructose-bisphosphate aldolase activity
LacP0761_RS01980	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
LacP0761_RS01980	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LacP0761_RS01980	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LacP0761_RS01985	COG1028	Short-chain dehydrogenase reductase Sdr
LacP0761_RS01995	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LacP0761_RS01995	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
LacP0761_RS02000	COG3715	PTS system
LacP0761_RS02005	COG3716	PTS system mannose fructose sorbose family IID component
LacP0761_RS02010	COG0246	Mannitol dehydrogenase
LacP0761_RS02015	COG1461	Dihydroxyacetone kinase
LacP0761_RS02020	COG2376	Dihydroxyacetone kinase
LacP0761_RS02025	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
LacP0761_RS02030	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
LacP0761_RS02035	COG1609	Transcriptional regulator
LacP0761_RS02045	COG2390	Transcriptional regulator
LacP0761_RS02055	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
LacP0761_RS02060	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LacP0761_RS02065	COG3715	PTS system
LacP0761_RS02070	COG3716	PTS system mannose fructose sorbose family IID component
LacP0761_RS02075	COG0191	fructose-bisphosphate aldolase activity
LacP0761_RS02080	COG0471	metal ion transport
LacP0761_RS02090	COG0583	DNA-binding transcription factor activity
LacP0761_RS02105	COG1122	ATPase activity
LacP0761_RS02160	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
LacP0761_RS02165	COG1349	DNA-binding transcription factor activity
LacP0761_RS02170	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
LacP0761_RS02180	COG1349	DNA-binding transcription factor activity
LacP0761_RS02210	COG0477	Major facilitator Superfamily
LacP0761_RS02230	COG4221	oxidoreductase activity
LacP0761_RS02255	COG0446	pyridine nucleotide-disulphide oxidoreductase
LacP0761_RS02260	COG0561	phosphatase activity
LacP0761_RS02270	COG1609	Transcriptional regulator
LacP0761_RS02275	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LacP0761_RS02285	COG3716	PTS system mannose fructose sorbose family IID component
LacP0761_RS02305	COG0366	Alpha amylase catalytic
LacP0761_RS02310	COG1132	(ABC) transporter
LacP0761_RS02330	COG1464	Belongs to the NlpA lipoprotein family
LacP0761_RS02355	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
LacP0761_RS02360	COG1461	Dihydroxyacetone kinase
LacP0761_RS02365	COG2376	Dihydroxyacetone kinase
LacP0761_RS02385	COG2814	Major facilitator Superfamily
LacP0761_RS02405	COG0028	Belongs to the TPP enzyme family
LacP0761_RS02420	COG2226	methyltransferase
LacP0761_RS02425	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
LacP0761_RS02430	COG0174	glutamine synthetase
LacP0761_RS02445	COG0789	Transcriptional regulator
LacP0761_RS02450	COG0656	L-ascorbic acid biosynthetic process
LacP0761_RS02465	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
LacP0761_RS02490	COG1131	(ABC) transporter
LacP0761_RS02510	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
LacP0761_RS02535	COG0308	aminopeptidase N
LacP0761_RS02540	COG0531	amino acid
LacP0761_RS02560	COG1028	Short-chain dehydrogenase reductase Sdr
LacP0761_RS02570	COG2271	Major facilitator Superfamily
LacP0761_RS02575	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
LacP0761_RS02580	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
LacP0761_RS02585	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
LacP0761_RS02730	COG2826	transposase and inactivated derivatives, IS30 family
LacP0761_RS02760	COG2801	Transposase and inactivated derivatives
LacP0761_RS02945	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
LacP0761_RS02990	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
LacP0761_RS03010	COG0783	Belongs to the Dps family
LacP0761_RS03020	COG2801	Transposase and inactivated derivatives
LacP0761_RS03030	COG0431	NADPH-dependent FMN reductase
LacP0761_RS03030	COG1053	succinate dehydrogenase
LacP0761_RS03030	COG3976	FMN-binding domain protein
LacP0761_RS03080	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
LacP0761_RS03105	COG4619	ABC transporter
LacP0761_RS03110	COG0390	transport system, permease component
LacP0761_RS03135	COG1174	glycine betaine transport
LacP0761_RS03145	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LacP0761_RS03160	COG0626	cystathionine gamma-synthase activity
LacP0761_RS03165	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LacP0761_RS03170	COG0765	amino acid transport
LacP0761_RS03180	COG1114	Component of the transport system for branched-chain amino acids
LacP0761_RS03225	COG0697	spore germination
LacP0761_RS03235	COG1131	(ABC) transporter
LacP0761_RS03250	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
LacP0761_RS03255	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
LacP0761_RS03260	COG1132	(ABC) transporter
LacP0761_RS03265	COG1132	(ABC) transporter
LacP0761_RS03270	COG2223	nitrite transmembrane transporter activity
LacP0761_RS03275	COG2188	Transcriptional regulator
LacP0761_RS03280	COG0366	Alpha amylase catalytic
LacP0761_RS03285	COG2190	(PTS) system
LacP0761_RS03285	COG1263	PTS System
LacP0761_RS03285	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LacP0761_RS03295	COG0531	amino acid
LacP0761_RS03300	COG0039	L-malate dehydrogenase activity
LacP0761_RS03305	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
LacP0761_RS03310	COG1278	Cold shock
LacP0761_RS03325	COG0488	(ABC) transporter
LacP0761_RS03330	COG0702	epimerase
LacP0761_RS03335	COG0656	L-ascorbic acid biosynthetic process
LacP0761_RS03340	COG1113	amino acid transport
LacP0761_RS03350	COG0025	NhaP-type Na H and K H
LacP0761_RS03395	COG0004	ammonium transporteR
LacP0761_RS03405	COG1285	pathogenesis
LacP0761_RS03425	COG1131	(ABC) transporter
LacP0761_RS03435	COG0488	(ABC) transporter
LacP0761_RS03440	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
LacP0761_RS03445	COG1573	uracil-dna glycosylase
LacP0761_RS03450	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
LacP0761_RS03455	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
LacP0761_RS03460	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
LacP0761_RS03465	COG1215	transferase activity, transferring glycosyl groups
LacP0761_RS03475	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
LacP0761_RS03480	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
LacP0761_RS03485	COG1609	Transcriptional regulator
LacP0761_RS03490	COG2017	converts alpha-aldose to the beta-anomer
LacP0761_RS03515	COG3775	system Galactitol-specific IIC component
LacP0761_RS03535	COG3684	Belongs to the aldolase LacD family
LacP0761_RS03550	COG1349	DNA-binding transcription factor activity
LacP0761_RS03565	COG0419	ATPase involved in DNA repair
LacP0761_RS03585	COG1194	a g-specific adenine glycosylase
LacP0761_RS03595	COG2249	NAD(P)H dehydrogenase (quinone) activity
LacP0761_RS03615	COG0351	phosphomethylpyrimidine kinase
LacP0761_RS03630	COG2910	NAD(P)H-binding
LacP0761_RS03635	COG1472	Belongs to the glycosyl hydrolase 3 family
LacP0761_RS03650	COG4120	Belongs to the binding-protein-dependent transport system permease family
LacP0761_RS03660	COG0604	alcohol dehydrogenase
LacP0761_RS03675	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
LacP0761_RS03685	COG0745	RESPONSE REGULATOR receiver
LacP0761_RS03690	COG5002	protein histidine kinase activity
LacP0761_RS03700	COG2508	Transcriptional regulator
LacP0761_RS03715	COG0778	Nitroreductase
LacP0761_RS03755	COG0604	alcohol dehydrogenase
LacP0761_RS03770	COG0628	permease
LacP0761_RS03795	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
LacP0761_RS03805	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
LacP0761_RS03810	COG3189	MarR family transcriptional regulator
LacP0761_RS03835	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
LacP0761_RS03860	COG0300	oxidoreductase activity
LacP0761_RS03865	COG0105	UTP biosynthetic process
LacP0761_RS03870	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
LacP0761_RS03875	COG2267	carboxylic ester hydrolase activity
LacP0761_RS03905	COG2267	carboxylic ester hydrolase activity
LacP0761_RS03940	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
LacP0761_RS03965	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
LacP0761_RS03970	COG0343	queuine tRNA-ribosyltransferase activity
LacP0761_RS03975	COG1862	Preprotein translocase
LacP0761_RS03980	COG1012	belongs to the aldehyde dehydrogenase family
LacP0761_RS03980	COG1454	alcohol dehydrogenase
LacP0761_RS03990	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
LacP0761_RS03995	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
LacP0761_RS04000	COG4109	DRTGG domain
LacP0761_RS04005	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
LacP0761_RS04010	COG0513	Belongs to the DEAD box helicase family
LacP0761_RS04055	COG3118	belongs to the thioredoxin family
LacP0761_RS04070	COG1696	Membrane protein involved in D-alanine export
LacP0761_RS04080	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
LacP0761_RS04085	COG1719	4-vinyl reductase, 4VR
LacP0761_RS04090	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
LacP0761_RS04100	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
LacP0761_RS04115	COG0668	transmembrane transport
LacP0761_RS04130	COG1827	regulation of RNA biosynthetic process
LacP0761_RS04135	COG0006	proline dipeptidase activity
LacP0761_RS04140	COG1609	Transcriptional regulator
LacP0761_RS04145	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
LacP0761_RS04150	COG1011	Hydrolase
LacP0761_RS04195	COG0737	Belongs to the 5'-nucleotidase family
LacP0761_RS04200	COG4470	Protein conserved in bacteria
LacP0761_RS04205	COG0647	UMP catabolic process
LacP0761_RS04215	COG0586	Pfam SNARE associated Golgi protein
LacP0761_RS04220	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
LacP0761_RS04235	COG1098	S1 RNA binding domain
LacP0761_RS04385	COG0531	amino acid
LacP0761_RS04390	COG0438	transferase activity, transferring glycosyl groups
LacP0761_RS04395	COG0438	transferase activity, transferring glycosyl groups
LacP0761_RS04410	COG0436	Aminotransferase
LacP0761_RS04420	COG1368	sulfuric ester hydrolase activity
LacP0761_RS04425	COG0735	belongs to the Fur family
LacP0761_RS04470	COG0477	Major facilitator Superfamily
LacP0761_RS04480	COG2814	Major facilitator Superfamily
LacP0761_RS04490	COG0671	phosphoesterase, PA-phosphatase related
LacP0761_RS04500	COG2244	polysaccharide biosynthetic process
LacP0761_RS04505	COG1187	pseudouridine synthase activity
LacP0761_RS04515	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
LacP0761_RS04535	COG0438	transferase activity, transferring glycosyl groups
LacP0761_RS04540	COG0386	Belongs to the glutathione peroxidase family
LacP0761_RS04545	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
LacP0761_RS04555	COG3830	Belongs to the UPF0237 family
LacP0761_RS04580	COG2357	RelA SpoT domain protein
LacP0761_RS04590	COG0564	pseudouridine synthase activity
LacP0761_RS04600	COG3142	Participates in the control of copper homeostasis
LacP0761_RS04610	COG2706	6-phosphogluconolactonase activity
LacP0761_RS04620	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
LacP0761_RS04635	COG2226	methyltransferase
LacP0761_RS04640	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
LacP0761_RS04650	COG1674	ftsk spoiiie
LacP0761_RS04655	COG0612	Peptidase, M16
LacP0761_RS04660	COG0612	Peptidase, M16
LacP0761_RS04665	COG1028	Short-chain dehydrogenase reductase Sdr
LacP0761_RS04670	COG1426	Protein conserved in bacteria
LacP0761_RS04675	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
LacP0761_RS04685	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
LacP0761_RS04700	COG1739	Uncharacterized protein family UPF0029
LacP0761_RS04705	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
LacP0761_RS04730	COG2884	Cell division ATP-binding protein ftsE
LacP0761_RS04735	COG2177	Part of the ABC transporter FtsEX involved in
LacP0761_RS04745	COG0745	RESPONSE REGULATOR receiver
LacP0761_RS04750	COG5002	protein histidine kinase activity
LacP0761_RS04760	COG0573	inorganic phosphate transmembrane transporter activity
LacP0761_RS04765	COG0581	inorganic phosphate transmembrane transporter activity
LacP0761_RS04770	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
LacP0761_RS04775	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
LacP0761_RS04780	COG0704	Plays a role in the regulation of phosphate uptake
LacP0761_RS04795	COG1950	PFAM Membrane protein of
LacP0761_RS04805	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
LacP0761_RS04815	COG0492	ferredoxin-NADP+ reductase activity
LacP0761_RS04820	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
LacP0761_RS04825	COG0745	RESPONSE REGULATOR receiver
LacP0761_RS04830	COG2205	protein histidine kinase activity
LacP0761_RS04835	COG1136	(ABC) transporter
LacP0761_RS04855	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
LacP0761_RS04870	COG0391	Required for morphogenesis under gluconeogenic growth conditions
LacP0761_RS04880	COG1846	Transcriptional regulator
LacP0761_RS04895	COG2390	Transcriptional regulator
LacP0761_RS04935	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
LacP0761_RS04945	COG0557	exoribonuclease II activity
LacP0761_RS04955	COG1609	Transcriptional regulator
LacP0761_RS04960	COG0366	Alpha amylase catalytic
LacP0761_RS04975	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
LacP0761_RS05005	COG0395	ABC-type sugar transport system, permease component
LacP0761_RS05010	COG1175	transmembrane transport
LacP0761_RS05030	COG0561	phosphatase activity
LacP0761_RS05040	COG0280	phosphate acetyltransferase
LacP0761_RS05045	COG0802	atpase or kinase
LacP0761_RS05050	COG4152	abc transporter atp-binding protein
LacP0761_RS05055	COG1668	transmembrane transport
LacP0761_RS05065	COG0708	Exodeoxyribonuclease III
LacP0761_RS05080	COG1396	sequence-specific DNA binding
LacP0761_RS05080	COG3800	Transcriptional regulator
LacP0761_RS05090	COG1176	ABC-type spermidine putrescine transport system, permease component I
LacP0761_RS05095	COG1177	transmembrane transport
LacP0761_RS05100	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
LacP0761_RS05115	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
LacP0761_RS05120	COG1309	transcriptional regulator
LacP0761_RS05150	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
LacP0761_RS05175	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
LacP0761_RS05180	COG1459	type II secretion system
LacP0761_RS05210	COG0827	DNA restriction-modification system
LacP0761_RS05220	COG1113	amino acid transport
LacP0761_RS05330	COG4695	Portal protein
LacP0761_RS05355	COG2261	transglycosylase associated protein
LacP0761_RS05435	COG4695	Portal protein
LacP0761_RS05460	COG2261	transglycosylase associated protein
LacP0761_RS05475	COG0745	RESPONSE REGULATOR receiver
LacP0761_RS05480	COG3850	Histidine kinase
LacP0761_RS05480	COG5002	protein histidine kinase activity
LacP0761_RS05510	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
LacP0761_RS05570	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
LacP0761_RS05575	COG2814	Major facilitator Superfamily
LacP0761_RS05580	COG0561	phosphatase activity
LacP0761_RS05585	COG2326	polyphosphate kinase activity
LacP0761_RS05590	COG3590	peptidase
LacP0761_RS05595	COG2814	Major facilitator Superfamily
LacP0761_RS05635	COG0673	inositol 2-dehydrogenase activity
LacP0761_RS05645	COG1447	Phosphotransferase system cellobiose-specific component IIA
LacP0761_RS05665	COG0514	ATP-dependent DNA helicase (RecQ)
LacP0761_RS05670	COG2309	aminopeptidase activity
LacP0761_RS05685	COG1295	ribonuclease BN
LacP0761_RS05690	COG0716	FMN binding
LacP0761_RS05695	COG0024	Methionine aminopeptidase
LacP0761_RS05700	COG0463	Glycosyl transferase, family 2
LacP0761_RS05720	COG1210	Utp--glucose-1-phosphate uridylyltransferase
LacP0761_RS05765	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LacP0761_RS05765	COG1263	PTS System
LacP0761_RS05765	COG2190	(PTS) system
LacP0761_RS05770	COG3711	transcriptional antiterminator
LacP0761_RS05775	COG4485	Bacterial membrane protein, YfhO
LacP0761_RS05785	COG0463	Glycosyl transferase, family 2
LacP0761_RS05795	COG4129	membrane
LacP0761_RS05805	COG1278	Cold shock
LacP0761_RS05815	COG1705	Flagellar rod assembly protein muramidase FlgJ
LacP0761_RS05830	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
LacP0761_RS05835	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
LacP0761_RS05850	COG1368	sulfuric ester hydrolase activity
LacP0761_RS05860	COG4975	Glucose uptake
LacP0761_RS05870	COG0582	viral genome integration into host DNA
LacP0761_RS05900	COG1396	sequence-specific DNA binding
LacP0761_RS05955	COG3935	DnaD domain protein
LacP0761_RS05960	COG0629	single-stranded DNA binding
LacP0761_RS06235	COG0590	tRNA wobble adenosine to inosine editing
LacP0761_RS06260	COG2814	Major facilitator Superfamily
LacP0761_RS06265	COG3548	integral membrane protein
LacP0761_RS06315	COG2514	catechol 2,3-dioxygenase activity
LacP0761_RS06330	COG2801	Transposase and inactivated derivatives
LacP0761_RS06335	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
LacP0761_RS06340	COG1435	thymidine kinase activity
LacP0761_RS06350	COG2890	protein-(glutamine-N5) methyltransferase activity
LacP0761_RS06355	COG0009	L-threonylcarbamoyladenylate synthase
LacP0761_RS06370	COG0356	it plays a direct role in the translocation of protons across the membrane
LacP0761_RS06415	COG1077	Cell shape determining protein MreB Mrl
LacP0761_RS06435	COG0772	Belongs to the SEDS family
LacP0761_RS06440	COG0509	glycine decarboxylation via glycine cleavage system
LacP0761_RS06445	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
LacP0761_RS06450	COG1464	Belongs to the NlpA lipoprotein family
LacP0761_RS06455	COG1464	Belongs to the NlpA lipoprotein family
LacP0761_RS06465	COG2011	ABC-type metal ion transport system permease component
LacP0761_RS06475	COG0719	Fe-S assembly protein
LacP0761_RS06480	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
LacP0761_RS06485	COG0822	iron-sulfur transferase activity
LacP0761_RS06490	COG0719	Fe-S assembly protein
LacP0761_RS06520	COG0589	response to stress
LacP0761_RS06530	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
LacP0761_RS06535	COG0189	ligase activity
LacP0761_RS06535	COG2918	glutathione biosynthetic process
LacP0761_RS06540	COG5506	Protein of unknown function (DUF1694)
LacP0761_RS06550	COG1760	l-serine dehydratase
LacP0761_RS06555	COG1760	l-serine dehydratase
LacP0761_RS06570	COG1028	Short-chain dehydrogenase reductase Sdr
LacP0761_RS06580	COG1428	Deoxynucleoside kinase
LacP0761_RS06590	COG4166	transmembrane transport
LacP0761_RS06595	COG2205	protein histidine kinase activity
LacP0761_RS06600	COG0745	RESPONSE REGULATOR receiver
LacP0761_RS06615	COG0583	DNA-binding transcription factor activity
LacP0761_RS06650	COG0454	-acetyltransferase
LacP0761_RS06665	COG1307	EDD domain protein, DegV family
LacP0761_RS06670	COG2197	response regulator
LacP0761_RS06675	COG4585	Histidine kinase
LacP0761_RS06685	COG1131	(ABC) transporter
LacP0761_RS06695	COG0789	Transcriptional regulator
LacP0761_RS06735	COG2183	response to ionizing radiation
LacP0761_RS06740	COG3620	sequence-specific DNA binding
LacP0761_RS06765	COG1956	GAF domain-containing protein
LacP0761_RS06770	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
LacP0761_RS06775	COG1104	cysteine desulfurase activity
LacP0761_RS06785	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
LacP0761_RS06790	COG0525	valine-tRNA ligase activity
LacP0761_RS06805	COG2003	Belongs to the UPF0758 family
LacP0761_RS06810	COG1077	Cell shape determining protein MreB Mrl
LacP0761_RS06815	COG1792	Involved in formation and maintenance of cell shape
LacP0761_RS06825	COG0850	regulation of cytokinetic process
LacP0761_RS06830	COG2894	cell division
LacP0761_RS06835	COG0765	amino acid transport
LacP0761_RS06845	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LacP0761_RS06850	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LacP0761_RS06865	COG2001	Belongs to the MraZ family
LacP0761_RS06880	COG0768	penicillin binding
LacP0761_RS06910	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
LacP0761_RS06930	COG3599	regulation of cell shape
LacP0761_RS06940	COG1278	Cold shock
LacP0761_RS06950	COG2814	Major facilitator Superfamily
LacP0761_RS06955	COG3853	Toxic anion resistance protein (TelA)
LacP0761_RS06965	COG0494	nUDIX hydrolase
LacP0761_RS06980	COG1104	cysteine desulfurase activity
LacP0761_RS06990	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
LacP0761_RS07010	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
LacP0761_RS07020	COG1597	lipid kinase activity
LacP0761_RS07085	COG0483	inositol monophosphate 1-phosphatase activity
LacP0761_RS07090	COG1217	gtp-binding protein TYPA
LacP0761_RS07095	COG0772	Belongs to the SEDS family
LacP0761_RS07100	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
LacP0761_RS07105	COG4471	UPF0298 protein
LacP0761_RS07110	COG0742	ribosomal rna small subunit methyltransferase
LacP0761_RS07120	COG3480	Lon protease (S16) C-terminal proteolytic domain
LacP0761_RS07130	COG2333	competence protein COMEC
LacP0761_RS07130	COG0658	competence protein
LacP0761_RS07135	COG1466	dna polymerase III delta subunit
LacP0761_RS07175	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
LacP0761_RS07190	COG1132	(ABC) transporter
LacP0761_RS07200	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
LacP0761_RS07220	COG0765	amino acid transport
LacP0761_RS07225	COG1126	abc transporter atp-binding protein
LacP0761_RS07235	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LacP0761_RS07235	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
LacP0761_RS07235	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LacP0761_RS07240	COG1105	Belongs to the carbohydrate kinase PfkB family
LacP0761_RS07245	COG1349	DNA-binding transcription factor activity
LacP0761_RS07255	COG2755	lipolytic protein G-D-S-L family
LacP0761_RS07255	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
LacP0761_RS07265	COG0300	oxidoreductase activity
LacP0761_RS07275	COG0542	response to heat
LacP0761_RS07290	COG0737	Belongs to the 5'-nucleotidase family
LacP0761_RS07305	COG0587	DNA-directed DNA polymerase activity
LacP0761_RS07325	COG2996	Protein conserved in bacteria
LacP0761_RS07335	COG0456	acetyltransferase
LacP0761_RS07340	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
LacP0761_RS07345	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
LacP0761_RS07350	COG1187	pseudouridine synthase activity
LacP0761_RS07355	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
LacP0761_RS07370	COG0514	ATP-dependent DNA helicase (RecQ)
LacP0761_RS07385	COG0539	negative regulation of cytoplasmic translation
LacP0761_RS07400	COG0457	Tetratricopeptide repeat
LacP0761_RS07405	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
LacP0761_RS07420	COG0488	(ABC) transporter
LacP0761_RS07435	COG1272	protein, Hemolysin III
LacP0761_RS07440	COG1307	EDD domain protein, DegV family
LacP0761_RS07445	COG2755	lipolytic protein G-D-S-L family
LacP0761_RS07455	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
LacP0761_RS07465	COG3409	Peptidoglycan-binding domain 1 protein
LacP0761_RS07465	COG0793	Belongs to the peptidase S41A family
LacP0761_RS07525	COG0758	DNA mediated transformation
LacP0761_RS07530	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
LacP0761_RS07550	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
LacP0761_RS07565	COG0187	DNA topoisomerase II activity
LacP0761_RS07570	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
LacP0761_RS07575	COG1882	Formate acetyltransferase
LacP0761_RS07580	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
LacP0761_RS07585	COG0583	DNA-binding transcription factor activity
LacP0761_RS07590	COG1227	inorganic diphosphatase activity
LacP0761_RS07595	COG4974	Belongs to the 'phage' integrase family
LacP0761_RS07605	COG0577	efflux transmembrane transporter activity
LacP0761_RS07610	COG1136	(ABC) transporter
LacP0761_RS07615	COG5002	protein histidine kinase activity
LacP0761_RS07620	COG0745	RESPONSE REGULATOR receiver
LacP0761_RS07640	COG0778	Nitroreductase
LacP0761_RS07645	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
LacP0761_RS07680	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
LacP0761_RS07695	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
LacP0761_RS07700	COG0494	nUDIX hydrolase
LacP0761_RS07705	COG1307	EDD domain protein, DegV family
LacP0761_RS07710	COG1293	RNA-binding protein homologous to eukaryotic snRNP
LacP0761_RS07725	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
LacP0761_RS07730	COG0508	dehydrogenase complex catalyzes the overall conversion of
LacP0761_RS07735	COG0022	dehydrogenase e1 component
LacP0761_RS07740	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
LacP0761_RS07745	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LacP0761_RS07750	COG3426	butyrate kinase activity
LacP0761_RS07755	COG0280	phosphate acetyltransferase
LacP0761_RS07760	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
LacP0761_RS07765	COG0284	orotidine-5'-phosphate decarboxylase activity
LacP0761_RS07780	COG0505	Belongs to the CarA family
LacP0761_RS07785	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
LacP0761_RS07795	COG2233	PERMEase
LacP0761_RS07800	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
LacP0761_RS07805	COG0564	pseudouridine synthase activity
LacP0761_RS07810	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
LacP0761_RS07825	COG0328	RNA-DNA hybrid ribonuclease activity
LacP0761_RS07835	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LacP0761_RS07850	COG1393	Belongs to the ArsC family
LacP0761_RS07855	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LacP0761_RS07860	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LacP0761_RS07865	COG0583	DNA-binding transcription factor activity
LacP0761_RS07870	COG3590	peptidase
LacP0761_RS07875	COG0095	Lipoate-protein ligase
LacP0761_RS07890	COG0116	Belongs to the methyltransferase superfamily
LacP0761_RS07915	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
LacP0761_RS07920	COG2131	deaminase
LacP0761_RS07925	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
LacP0761_RS07940	COG0436	Aminotransferase
LacP0761_RS07950	COG1199	ATP-dependent helicase activity
LacP0761_RS07950	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
LacP0761_RS07985	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
LacP0761_RS07985	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
LacP0761_RS08000	COG2151	metal-sulfur cluster biosynthetic enzyme
LacP0761_RS08005	COG1942	4-Oxalocrotonate Tautomerase
LacP0761_RS08010	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
LacP0761_RS08015	COG2384	SAM-dependent methyltransferase
LacP0761_RS08020	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
LacP0761_RS08025	COG0358	DNA primase activity
LacP0761_RS08050	COG1381	Involved in DNA repair and RecF pathway recombination
LacP0761_RS08060	COG0295	cytidine deaminase activity
LacP0761_RS08075	COG1702	phosphate starvation-inducible protein PhoH
LacP0761_RS08080	COG1610	YqeY-like protein
LacP0761_RS08095	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
LacP0761_RS08100	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
LacP0761_RS08105	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
LacP0761_RS08135	COG1131	(ABC) transporter
LacP0761_RS08145	COG4991	sh3 domain protein
LacP0761_RS08145	COG3103	Sh3 type 3 domain protein
LacP0761_RS08145	COG0860	N-Acetylmuramoyl-L-alanine amidase
LacP0761_RS08160	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
LacP0761_RS08170	COG1385	rRNA (uridine-N3-)-methyltransferase activity
LacP0761_RS08185	COG2094	Belongs to the DNA glycosylase MPG family
LacP0761_RS08220	COG0673	inositol 2-dehydrogenase activity
LacP0761_RS08225	COG0438	transferase activity, transferring glycosyl groups
LacP0761_RS08285	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
LacP0761_RS08295	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
LacP0761_RS08295	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
LacP0761_RS08325	COG1132	(ABC) transporter
LacP0761_RS08340	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
LacP0761_RS08350	COG0635	Involved in the biosynthesis of porphyrin-containing compound
LacP0761_RS08355	COG0196	riboflavin kinase activity
LacP0761_RS08365	COG0861	Integral membrane protein TerC family
LacP0761_RS08385	COG2740	Nucleic-acid-binding protein implicated in transcription termination
LacP0761_RS08390	COG0195	Participates in both transcription termination and antitermination
LacP0761_RS08410	COG0750	zinc metalloprotease
LacP0761_RS08415	COG4589	Belongs to the CDS family
LacP0761_RS08420	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
LacP0761_RS08450	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
LacP0761_RS08455	COG0204	Acyl-transferase
LacP0761_RS08460	COG0531	amino acid
LacP0761_RS08470	COG1132	(ABC) transporter
LacP0761_RS08475	COG1132	(ABC) transporter
LacP0761_RS08480	COG3763	UPF0154 protein
LacP0761_RS08485	COG4224	UPF0291 protein
LacP0761_RS08510	COG1837	Belongs to the UPF0109 family
LacP0761_RS08520	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
LacP0761_RS08535	COG0552	protein localization to endoplasmic reticulum
LacP0761_RS08540	COG1196	nuclear chromosome segregation
LacP0761_RS08545	COG0571	ribonuclease III activity
LacP0761_RS08555	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LacP0761_RS08560	COG0601	transmembrane transport
LacP0761_RS08565	COG4608	Belongs to the ABC transporter superfamily
LacP0761_RS08575	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LacP0761_RS08585	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
LacP0761_RS08590	COG1461	Dihydroxyacetone kinase
LacP0761_RS08605	COG1564	THIamine pyrophosphokinase
LacP0761_RS08610	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
LacP0761_RS08615	COG1162	GTPase activity
LacP0761_RS08620	COG2815	serine threonine protein kinase
LacP0761_RS08620	COG0515	serine threonine protein kinase
LacP0761_RS08630	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
LacP0761_RS08630	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
LacP0761_RS08640	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
LacP0761_RS08645	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
LacP0761_RS08655	COG0194	GDP metabolic process
LacP0761_RS08670	COG0497	DNA recombination
LacP0761_RS08675	COG1438	arginine binding
LacP0761_RS08680	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
LacP0761_RS08685	COG0142	geranyltranstransferase activity
LacP0761_RS08690	COG1722	exodeoxyribonuclease VII activity
LacP0761_RS08710	COG1302	Protein conserved in bacteria
LacP0761_RS08715	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
LacP0761_RS08720	COG0006	proline dipeptidase activity
LacP0761_RS08725	COG0211	Belongs to the bacterial ribosomal protein bL27 family
LacP0761_RS08730	COG2868	ribosomal protein
LacP0761_RS08735	COG0261	This protein binds to 23S rRNA in the presence of protein L20
LacP0761_RS08765	COG0789	Transcriptional regulator
LacP0761_RS08770	COG1982	Orn Lys Arg decarboxylase major
LacP0761_RS08775	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
LacP0761_RS08790	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
LacP0761_RS08795	COG1940	carbohydrate kinase activity
LacP0761_RS08805	COG0705	Rhomboid family
LacP0761_RS08805	COG0457	Tetratricopeptide repeat
LacP0761_RS08810	COG0768	penicillin binding
LacP0761_RS08820	COG4841	protein insertion into membrane
LacP0761_RS08825	COG2197	response regulator
LacP0761_RS08840	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
LacP0761_RS08845	COG0572	uridine kinase
LacP0761_RS08850	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
LacP0761_RS08855	COG0072	phenylalanine-tRNA ligase activity
LacP0761_RS08865	COG1733	regulation of RNA biosynthetic process
LacP0761_RS08875	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LacP0761_RS08885	COG0706	membrane insertase activity
LacP0761_RS08890	COG5002	protein histidine kinase activity
LacP0761_RS08895	COG0745	RESPONSE REGULATOR receiver
LacP0761_RS08900	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
LacP0761_RS08920	COG2226	methyltransferase
LacP0761_RS08925	COG0799	negative regulation of ribosome biogenesis
LacP0761_RS08935	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
LacP0761_RS08940	COG1534	Rna-binding protein
LacP0761_RS08945	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
LacP0761_RS08950	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
LacP0761_RS08955	COG0346	lactoylglutathione lyase activity
LacP0761_RS08965	COG0400	carboxylic ester hydrolase activity
LacP0761_RS08990	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
LacP0761_RS09020	COG1484	DNA-dependent DNA replication
LacP0761_RS09025	COG3611	Membrane attachment protein
LacP0761_RS09035	COG0237	dephospho-CoA kinase activity
LacP0761_RS09040	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
LacP0761_RS09045	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
LacP0761_RS09045	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
LacP0761_RS09050	COG0670	Belongs to the BI1 family
LacP0761_RS09060	COG1674	ftsk spoiiie
LacP0761_RS09065	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LacP0761_RS09070	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LacP0761_RS09095	COG1131	(ABC) transporter
LacP0761_RS09100	COG0537	adenosine 5'-monophosphoramidase activity
LacP0761_RS09110	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
LacP0761_RS09125	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
LacP0761_RS09130	COG0564	pseudouridine synthase activity
LacP0761_RS09135	COG1438	arginine binding
LacP0761_RS09140	COG0018	arginyl-trna synthetase
LacP0761_RS09160	COG0167	dihydroorotate dehydrogenase activity
LacP0761_RS09175	COG1393	Belongs to the ArsC family
LacP0761_RS09180	COG1234	tRNA 3'-trailer cleavage
LacP0761_RS09195	COG1136	(ABC) transporter
LacP0761_RS09200	COG0745	RESPONSE REGULATOR receiver
LacP0761_RS09205	COG0642	Histidine kinase
LacP0761_RS09215	COG2217	Heavy metal translocating P-type atpase
LacP0761_RS09220	COG3682	Transcriptional regulator
LacP0761_RS09230	COG0151	Belongs to the GarS family
LacP0761_RS09240	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
LacP0761_RS09245	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
LacP0761_RS09265	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
LacP0761_RS09275	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
LacP0761_RS09280	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
LacP0761_RS09290	COG2814	Major facilitator Superfamily
LacP0761_RS09300	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
LacP0761_RS09310	COG0542	response to heat
LacP0761_RS09325	COG1253	flavin adenine dinucleotide binding
LacP0761_RS09330	COG0628	permease
LacP0761_RS09345	COG3557	Belongs to the UPF0374 family
LacP0761_RS09365	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
LacP0761_RS09375	COG2188	Transcriptional regulator
LacP0761_RS09380	COG2723	6-phospho-beta-galactosidase activity
LacP0761_RS09385	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
LacP0761_RS09395	COG1447	Phosphotransferase system cellobiose-specific component IIA
LacP0761_RS09400	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
LacP0761_RS09405	COG0028	Belongs to the TPP enzyme family
LacP0761_RS09410	COG3425	synthase
LacP0761_RS09420	COG0183	Belongs to the thiolase family
LacP0761_RS09445	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
LacP0761_RS09465	COG3091	SprT-like family
LacP0761_RS09470	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
LacP0761_RS09475	COG4120	Belongs to the binding-protein-dependent transport system permease family
LacP0761_RS09510	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
LacP0761_RS09515	COG2188	Transcriptional regulator
LacP0761_RS09520	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
LacP0761_RS09525	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
LacP0761_RS09530	COG4946	Tricorn protease homolog
LacP0761_RS09530	COG0823	Involved in the tonB-independent uptake of proteins
LacP0761_RS09530	COG1506	peptidase
LacP0761_RS09545	COG3104	oligopeptide transport
LacP0761_RS09550	COG0577	efflux transmembrane transporter activity
LacP0761_RS09550	COG1136	(ABC) transporter
LacP0761_RS09675	COG0833	amino acid
LacP0761_RS09690	COG0028	Belongs to the TPP enzyme family
LacP0761_RS09700	COG0519	Catalyzes the synthesis of GMP from XMP
LacP0761_RS09725	COG0564	pseudouridine synthase activity
LacP0761_RS09745	COG3697	Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase
LacP0761_RS09745	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
LacP0761_RS09760	COG3697	Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase
LacP0761_RS09760	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
LacP0761_RS09795	COG0511	ligase activity, forming carbon-carbon bonds
LacP0761_RS09805	COG2851	Citrate transporter
LacP0761_RS09845	COG1131	(ABC) transporter
LacP0761_RS09860	COG2814	Major facilitator Superfamily
LacP0761_RS09880	COG1725	Transcriptional regulator
LacP0761_RS09885	COG1131	(ABC) transporter
LacP0761_RS09900	COG1136	(ABC) transporter
LacP0761_RS09910	COG4608	Belongs to the ABC transporter superfamily
LacP0761_RS09915	COG0444	Belongs to the ABC transporter superfamily
LacP0761_RS09925	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LacP0761_RS09930	COG0601	transmembrane transport
LacP0761_RS09935	COG4166	transmembrane transport
LacP0761_RS09945	COG0640	Transcriptional regulator
LacP0761_RS09980	COG5549	protein import
LacP0761_RS09980	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LacP0761_RS09990	COG1349	DNA-binding transcription factor activity
LacP0761_RS10065	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
LacP0761_RS10070	COG1061	Type III restriction enzyme res subunit
LacP0761_RS10075	COG1002	Type II restriction enzyme, methylase subunits
LacP0761_RS10105	COG4690	dipeptidase activity
LacP0761_RS10110	COG1607	acyl-coa hydrolase
LacP0761_RS10115	COG3973	AAA domain
LacP0761_RS10125	COG0475	glutathione-regulated potassium exporter activity
LacP0761_RS10125	COG0569	domain protein
LacP0761_RS10130	COG2267	carboxylic ester hydrolase activity
LacP0761_RS10160	COG1136	(ABC) transporter
LacP0761_RS10165	COG0531	amino acid
LacP0761_RS10170	COG1597	lipid kinase activity
LacP0761_RS10175	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
LacP0761_RS10180	COG0726	polysaccharide deacetylase
LacP0761_RS10195	COG0489	protein tyrosine kinase activity
LacP0761_RS10215	COG0463	Glycosyl transferase, family 2
LacP0761_RS10245	COG0463	Glycosyl transferase, family 2
LacP0761_RS10250	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
LacP0761_RS10260	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
LacP0761_RS10280	COG0765	amino acid transport
LacP0761_RS10285	COG0765	amino acid transport
LacP0761_RS10290	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LacP0761_RS10310	COG0735	belongs to the Fur family
LacP0761_RS10320	COG0194	GDP metabolic process
LacP0761_RS10325	COG0456	acetyltransferase
LacP0761_RS10325	COG0454	-acetyltransferase
LacP0761_RS10345	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
LacP0761_RS10370	COG0058	SHG alpha-glucan phosphorylase activity
LacP0761_RS10380	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
LacP0761_RS10390	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
LacP0761_RS10395	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
LacP0761_RS10405	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
LacP0761_RS10415	COG1393	Belongs to the ArsC family
LacP0761_RS10430	COG1091	dTDP-4-dehydrorhamnose reductase activity
LacP0761_RS10435	COG1088	dTDP-glucose 4,6-dehydratase activity
LacP0761_RS10445	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
LacP0761_RS10450	COG4464	protein tyrosine phosphatase activity
LacP0761_RS10455	COG1316	TRANSCRIPTIONal
LacP0761_RS10465	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
LacP0761_RS10475	COG0438	transferase activity, transferring glycosyl groups
LacP0761_RS10490	COG0438	transferase activity, transferring glycosyl groups
LacP0761_RS10510	COG0489	protein tyrosine kinase activity
LacP0761_RS10525	COG4708	membrane
LacP0761_RS10530	COG1028	Short-chain dehydrogenase reductase Sdr
LacP0761_RS10550	COG4608	Belongs to the ABC transporter superfamily
LacP0761_RS10555	COG0444	Belongs to the ABC transporter superfamily
LacP0761_RS10560	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LacP0761_RS10565	COG0601	transmembrane transport
LacP0761_RS10570	COG4166	transmembrane transport
LacP0761_RS10575	COG2814	Major facilitator Superfamily
LacP0761_RS10580	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
LacP0761_RS10585	COG1556	Lactate utilization protein
LacP0761_RS10590	COG1139	Iron-sulfur cluster binding protein
LacP0761_RS10605	COG1447	Phosphotransferase system cellobiose-specific component IIA
LacP0761_RS10625	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
LacP0761_RS10660	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LacP0761_RS10750	COG2190	(PTS) system
LacP0761_RS10750	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LacP0761_RS10750	COG1263	PTS System
LacP0761_RS10755	COG0366	Alpha amylase catalytic
LacP0761_RS10760	COG1609	Transcriptional regulator
LacP0761_RS10770	COG0702	epimerase
LacP0761_RS10775	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
LacP0761_RS10795	COG0439	Biotin carboxylase
LacP0761_RS10805	COG0511	ligase activity, forming carbon-carbon bonds
LacP0761_RS10810	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
LacP0761_RS10815	COG1028	Short-chain dehydrogenase reductase Sdr
LacP0761_RS10830	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LacP0761_RS10835	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
LacP0761_RS10845	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
LacP0761_RS10850	COG2267	carboxylic ester hydrolase activity
LacP0761_RS10855	COG1979	alcohol dehydrogenase
LacP0761_RS10885	COG1846	Transcriptional regulator
LacP0761_RS10895	COG0494	nUDIX hydrolase
LacP0761_RS10900	COG0588	phosphoglycerate mutase activity
LacP0761_RS10920	COG0628	permease
LacP0761_RS10935	COG1597	lipid kinase activity
LacP0761_RS10940	COG0028	Belongs to the TPP enzyme family
LacP0761_RS10985	COG0460	homoserine dehydrogenase
LacP0761_RS10990	COG0527	aspartate kinase activity
LacP0761_RS10995	COG2268	Band 7 protein
LacP0761_RS11010	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LacP0761_RS11015	COG0436	Aminotransferase
LacP0761_RS11035	COG0367	asparagine synthase
LacP0761_RS11060	COG0142	geranyltranstransferase activity
LacP0761_RS11070	COG4152	abc transporter atp-binding protein
LacP0761_RS11085	COG1131	(ABC) transporter
LacP0761_RS11110	COG1297	OPT oligopeptide transporter protein
LacP0761_RS11130	COG0477	Major facilitator Superfamily
LacP0761_RS11140	COG2723	6-phospho-beta-galactosidase activity
LacP0761_RS11145	COG2190	(PTS) system
LacP0761_RS11145	COG1263	PTS System
LacP0761_RS11145	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LacP0761_RS11155	COG1132	(ABC) transporter
LacP0761_RS11160	COG1132	(ABC) transporter
LacP0761_RS11185	COG1518	maintenance of DNA repeat elements
LacP0761_RS11190	COG3513	CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
LacP0761_RS11215	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
LacP0761_RS11220	COG4988	ABC transporter
LacP0761_RS11225	COG1294	oxidase, subunit
LacP0761_RS11230	COG1271	oxidase subunit
LacP0761_RS11260	COG0697	spore germination
LacP0761_RS11265	COG2818	Glycosylase
LacP0761_RS11280	COG2365	Tyrosine phosphatase family
LacP0761_RS11285	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
LacP0761_RS11295	COG1268	BioY protein
LacP0761_RS11300	COG0789	Transcriptional regulator
LacP0761_RS11310	COG1063	alcohol dehydrogenase
LacP0761_RS11330	COG2264	protein methyltransferase activity
LacP0761_RS11340	COG0505	Belongs to the CarA family
LacP0761_RS11350	COG1253	flavin adenine dinucleotide binding
LacP0761_RS11355	COG2814	Major facilitator Superfamily
LacP0761_RS11380	COG0531	amino acid
LacP0761_RS11400	COG1266	CAAX protease self-immunity
LacP0761_RS11405	COG1316	TRANSCRIPTIONal
LacP0761_RS11415	COG1131	(ABC) transporter
LacP0761_RS11420	COG1725	Transcriptional regulator
LacP0761_RS11425	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
LacP0761_RS11430	COG0488	(ABC) transporter
LacP0761_RS11440	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
LacP0761_RS11450	COG0456	acetyltransferase
LacP0761_RS11450	COG1214	PFAM Peptidase M22, glycoprotease
LacP0761_RS11455	COG1214	PFAM Peptidase M22, glycoprotease
LacP0761_RS11495	COG0470	DNA polymerase III
LacP0761_RS11500	COG3870	Protein conserved in bacteria
LacP0761_RS11525	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
LacP0761_RS11535	COG0590	tRNA wobble adenosine to inosine editing
LacP0761_RS11545	COG2813	Specifically methylates the guanine in position
LacP0761_RS11550	COG0392	lysyltransferase activity
LacP0761_RS11550	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
LacP0761_RS11560	COG1609	Transcriptional regulator
LacP0761_RS11605	COG0477	Major facilitator Superfamily
LacP0761_RS11610	COG1012	belongs to the aldehyde dehydrogenase family
LacP0761_RS11625	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
LacP0761_RS11635	COG5646	InterPro IPR014922
LacP0761_RS11640	COG2096	Adenosyltransferase
LacP0761_RS11670	COG0250	Participates in transcription elongation, termination and antitermination
LacP0761_RS11700	COG4939	FMN-binding domain protein
LacP0761_RS11740	COG1131	(ABC) transporter
LacP0761_RS11760	COG3688	RNA-binding protein containing a PIN domain
LacP0761_RS11765	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LacP0761_RS11770	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
LacP0761_RS11780	COG0277	FAD linked oxidase domain protein
LacP0761_RS11805	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
LacP0761_RS11810	COG1737	Transcriptional regulator
LacP0761_RS11815	COG4377	Putative membrane peptidase family (DUF2324)
LacP0761_RS11830	COG4886	Leucine-rich repeat (LRR) protein
LacP0761_RS11830	COG4932	domain protein
LacP0761_RS11865	COG4956	integral membrane protein (PIN domain superfamily)
LacP0761_RS11870	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
LacP0761_RS11875	COG0756	dUTP diphosphatase activity
LacP0761_RS11880	COG2388	GCN5-related N-acetyl-transferase
LacP0761_RS11920	COG1131	(ABC) transporter
LacP0761_RS11930	COG0574	Belongs to the PEP-utilizing enzyme family
LacP0761_RS11930	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
LacP0761_RS11935	COG0517	IMP dehydrogenase activity
LacP0761_RS11940	COG0588	phosphoglycerate mutase activity
LacP0761_RS11955	COG1304	FMN binding
LacP0761_RS11990	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
LacP0761_RS12010	COG3764	Sortase (surface protein transpeptidase)
LacP0761_RS12050	COG1695	Transcriptional regulator
LacP0761_RS12095	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LacP0761_RS12100	COG2274	protein secretion by the type I secretion system
LacP0761_RS12165	COG0110	maltose O-acetyltransferase activity
LacP0761_RS12185	COG4989	oxidoreductase activity
LacP0761_RS12190	COG4221	oxidoreductase activity
LacP0761_RS12195	COG1902	pentaerythritol trinitrate reductase activity
LacP0761_RS12200	COG0114	fumarate hydratase activity
LacP0761_RS12210	COG1914	H( )-stimulated, divalent metal cation uptake system
LacP0761_RS12215	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
LacP0761_RS12225	COG2814	Major facilitator Superfamily
LacP0761_RS12255	COG1108	ABC-type Mn2 Zn2 transport systems permease components
LacP0761_RS12260	COG1121	(ABC) transporter
LacP0761_RS12265	COG1012	belongs to the aldehyde dehydrogenase family
LacP0761_RS12355	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
LacP0761_RS12370	COG0148	phosphopyruvate hydratase activity
LacP0761_RS12375	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
LacP0761_RS12395	COG3639	organic phosphonate transmembrane transporter activity
LacP0761_RS12415	COG1116	anion transmembrane transporter activity
LacP0761_RS12420	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
LacP0761_RS12435	COG4555	ABC transporter
LacP0761_RS12475	COG0577	efflux transmembrane transporter activity
LacP0761_RS12480	COG1136	(ABC) transporter
LacP0761_RS12490	COG0789	Transcriptional regulator
LacP0761_RS12570	COG0200	Binds to the 23S rRNA
LacP0761_RS12680	COG0450	alkyl hydroperoxide reductase
LacP0761_RS12725	COG0542	response to heat
LacP0761_RS12730	COG4463	regulation of RNA biosynthetic process
LacP0761_RS12800	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
LacP0761_RS12805	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
LacP0761_RS12845	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
LacP0761_RS12850	COG0037	tRNA processing
LacP0761_RS12855	COG1098	S1 RNA binding domain
LacP0761_RS12865	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
LacP0761_RS12870	COG2244	polysaccharide biosynthetic process
LacP0761_RS12875	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
LacP0761_RS12885	COG0039	L-malate dehydrogenase activity
LacP0761_RS12900	COG1376	ErfK ybiS ycfS ynhG family protein
LacP0761_RS12905	COG0493	'glutamate synthase
LacP0761_RS12910	COG0070	glutamate synthase
LacP0761_RS12910	COG0067	glutamate synthase
LacP0761_RS12910	COG0069	glutamate synthase activity
LacP0761_RS12915	COG4708	membrane
LacP0761_RS12920	COG2337	Toxic component of a toxin-antitoxin (TA) module
LacP0761_RS12950	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
LacP0761_RS12985	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
LacP0761_RS12995	COG0504	CTP synthase activity
LacP0761_RS13015	COG0095	Lipoate-protein ligase
LacP0761_RS13020	COG1078	dGTPase activity
LacP0761_RS13050	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
LacP0761_RS13055	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
LacP0761_RS13065	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
LacP0761_RS13070	COG4619	ABC transporter
LacP0761_RS13075	COG0390	transport system, permease component
LacP0761_RS13085	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
LacP0761_RS13090	COG4466	Protein conserved in bacteria
LacP0761_RS13095	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
LacP0761_RS13100	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
LacP0761_RS13105	COG0084	hydrolase, TatD family'
LacP0761_RS13115	COG3684	Belongs to the aldolase LacD family
LacP0761_RS13130	COG3290	protein histidine kinase activity
LacP0761_RS13145	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LacP0761_RS13145	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LacP0761_RS13155	COG1801	Protein of unknown function DUF72
LacP0761_RS13175	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
LacP0761_RS13190	COG1881	PFAM PEBP family protein
LacP0761_RS13200	COG4086	secreted protein
LacP0761_RS13205	COG0248	Ppx GppA phosphatase
LacP0761_RS13210	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
LacP0761_RS13220	COG4989	oxidoreductase activity
LacP0761_RS13225	COG2226	methyltransferase
LacP0761_RS13235	COG0534	Mate efflux family protein
LacP0761_RS13240	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
LacP0761_RS13245	COG1704	LemA family
LacP0761_RS13255	COG0577	efflux transmembrane transporter activity
LacP0761_RS13255	COG1136	(ABC) transporter
LacP0761_RS13260	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LacP0761_RS13270	COG1174	glycine betaine transport
LacP0761_RS13275	COG3973	AAA domain
LacP0761_RS13300	COG1418	mRNA catabolic process
LacP0761_RS13310	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
LacP0761_RS13315	COG0667	Aldo Keto reductase
LacP0761_RS13320	COG0561	phosphatase activity
LacP0761_RS13340	COG0588	phosphoglycerate mutase activity
LacP0761_RS13345	COG0561	phosphatase activity
LacP0761_RS13360	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LacP0761_RS13365	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
LacP0761_RS13370	COG1811	Na channel or pump
LacP0761_RS13380	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LacP0761_RS13380	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LacP0761_RS13380	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
LacP0761_RS13385	COG1105	Belongs to the carbohydrate kinase PfkB family
LacP0761_RS13395	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
LacP0761_RS13415	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
LacP0761_RS13415	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LacP0761_RS13420	COG3715	PTS system
LacP0761_RS13425	COG3716	PTS system mannose fructose sorbose family IID component
LacP0761_RS13430	COG1447	Phosphotransferase system cellobiose-specific component IIA
LacP0761_RS13440	COG2723	6-phospho-beta-galactosidase activity
LacP0761_RS13445	COG1940	carbohydrate kinase activity
LacP0761_RS13460	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
LacP0761_RS13465	COG2188	Transcriptional regulator
LacP0761_RS13480	COG3775	system Galactitol-specific IIC component
LacP0761_RS13495	COG1349	DNA-binding transcription factor activity
LacP0761_RS13505	COG0366	Alpha amylase catalytic
LacP0761_RS13535	COG0463	Glycosyl transferase, family 2
LacP0761_RS13545	COG0586	Pfam SNARE associated Golgi protein
LacP0761_RS13550	COG0745	RESPONSE REGULATOR receiver
LacP0761_RS13560	COG1263	PTS System
LacP0761_RS13560	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LacP0761_RS13590	COG3711	transcriptional antiterminator
LacP0761_RS13600	COG2190	(PTS) system
LacP0761_RS13600	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LacP0761_RS13600	COG1263	PTS System
LacP0761_RS13640	COG3414	Phosphotransferase system galactitol-specific IIB component
LacP0761_RS13645	COG3775	system Galactitol-specific IIC component
LacP0761_RS13670	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
LacP0761_RS13685	COG2204	response regulator
LacP0761_RS13710	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
LacP0761_RS13715	COG0800	Aldolase
LacP0761_RS13735	COG3964	amidohydrolase
LacP0761_RS13780	COG3732	PTS system glucitol sorbitol-specific
LacP0761_RS13785	COG3730	PTS system glucitol sorbitol-specific
LacP0761_RS13795	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
LacP0761_RS13795	COG3711	transcriptional antiterminator
LacP0761_RS13805	COG2190	(PTS) system
LacP0761_RS13805	COG1263	PTS System
LacP0761_RS13805	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LacP0761_RS13815	COG2723	6-phospho-beta-galactosidase activity
LacP0761_RS13820	COG1609	Transcriptional regulator
LacP0761_RS13825	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LacP0761_RS13825	COG2190	(PTS) system
LacP0761_RS13825	COG1263	PTS System
LacP0761_RS13835	COG0561	phosphatase activity
LacP0761_RS13840	COG3623	hexulose-6-phosphate isomerase
LacP0761_RS13845	COG1349	DNA-binding transcription factor activity
LacP0761_RS13850	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
LacP0761_RS13870	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
LacP0761_RS13885	COG1063	alcohol dehydrogenase
LacP0761_RS13900	COG3716	PTS system mannose fructose sorbose family IID component
LacP0761_RS13905	COG3715	PTS system
LacP0761_RS13910	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LacP0761_RS13920	COG1063	alcohol dehydrogenase
LacP0761_RS13925	COG1349	DNA-binding transcription factor activity
LacP0761_RS13930	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
LacP0761_RS13940	COG1446	asparaginase
LacP0761_RS13945	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
LacP0761_RS13950	COG2188	Transcriptional regulator
LacP0761_RS13975	COG1070	Carbohydrate kinase
LacP0761_RS13980	COG1063	alcohol dehydrogenase
LacP0761_RS13985	COG3716	PTS system mannose fructose sorbose family IID component
LacP0761_RS13995	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
LacP0761_RS13995	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LacP0761_RS14005	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
LacP0761_RS14005	COG3711	transcriptional antiterminator
LacP0761_RS14015	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
LacP0761_RS14020	COG3775	system Galactitol-specific IIC component
LacP0761_RS14035	COG0191	fructose-bisphosphate aldolase activity
LacP0761_RS14040	COG2188	Transcriptional regulator
LacP0761_RS14055	COG0477	Major facilitator Superfamily
LacP0761_RS14060	COG0456	acetyltransferase
LacP0761_RS14095	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
LacP0761_RS14115	COG3842	ATPase activity
LacP0761_RS14120	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
LacP0761_RS14125	COG1335	isochorismatase
LacP0761_RS14140	COG4948	Mandelate Racemase Muconate Lactonizing
LacP0761_RS14150	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
LacP0761_RS14155	COG1737	Transcriptional regulator
LacP0761_RS14160	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LacP0761_RS14165	COG3716	PTS system mannose fructose sorbose family IID component
LacP0761_RS14180	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
LacP0761_RS14190	COG2076	Multidrug Resistance protein
LacP0761_RS14215	COG0604	alcohol dehydrogenase
LacP0761_RS14220	COG2365	Tyrosine phosphatase family
LacP0761_RS14230	COG0789	Transcriptional regulator
LacP0761_RS14235	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LacP0761_RS14260	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
LacP0761_RS14275	COG4166	transmembrane transport
LacP0761_RS14285	COG2217	Heavy metal translocating P-type atpase
LacP0761_RS14300	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LacP0761_RS14305	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
LacP0761_RS14320	COG5002	protein histidine kinase activity
LacP0761_RS14325	COG0745	RESPONSE REGULATOR receiver
LacP0761_RS14330	COG0596	Alpha beta hydrolase
LacP0761_RS14335	COG0765	amino acid transport
LacP0761_RS14360	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
LacP0761_RS14365	COG2188	Transcriptional regulator
LacP0761_RS14370	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
LacP0761_RS14375	COG1447	Phosphotransferase system cellobiose-specific component IIA
LacP0761_RS14395	COG1335	isochorismatase
LacP0761_RS14400	COG2814	Major facilitator Superfamily
LacP0761_RS14405	COG2807	transmembrane transport
LacP0761_RS14410	COG0667	Aldo Keto reductase
LacP0761_RS14420	COG3716	PTS system mannose fructose sorbose family IID component
LacP0761_RS14425	COG3715	PTS system
LacP0761_RS14460	COG0765	amino acid transport
LacP0761_RS14465	COG1126	abc transporter atp-binding protein
LacP0761_RS14505	COG4133	protoheme IX ABC transporter activity
LacP0761_RS14510	COG3001	Fructosamine kinase
LacP0761_RS14520	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LacP0761_RS14525	COG0765	amino acid transport
LacP0761_RS14540	COG0714	Associated with various cellular activities
LacP0761_RS14550	COG1305	Transglutaminase-like
LacP0761_RS14555	COG0438	transferase activity, transferring glycosyl groups
LacP0761_RS14560	COG0110	maltose O-acetyltransferase activity
LacP0761_RS14565	COG0561	phosphatase activity
LacP0761_RS14590	COG3493	citrate carrier protein
LacP0761_RS14595	COG3290	protein histidine kinase activity
LacP0761_RS14600	COG4565	transcriptional regulatory protein
LacP0761_RS14645	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LacP0761_RS14645	COG1263	PTS System
LacP0761_RS14650	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LacP0761_RS14650	COG1263	PTS System
LacP0761_RS14650	COG2190	(PTS) system
LacP0761_RS14655	COG3711	transcriptional antiterminator
LacP0761_RS14665	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
LacP0761_RS14685	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
LacP0761_RS14695	COG2213	PTS system mannitol-specific
LacP0761_RS14705	COG0561	phosphatase activity
LacP0761_RS14725	COG1136	(ABC) transporter
LacP0761_RS14725	COG0577	efflux transmembrane transporter activity
LacP0761_RS14730	COG0577	efflux transmembrane transporter activity
LacP0761_RS14740	COG2723	6-phospho-beta-galactosidase activity
LacP0761_RS14745	COG2190	(PTS) system
LacP0761_RS14745	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LacP0761_RS14745	COG1263	PTS System
LacP0761_RS14770	COG0371	Dehydrogenase
LacP0761_RS14775	COG1473	amidohydrolase
LacP0761_RS14810	COG0706	membrane insertase activity
LacP0761_RS14850	COG1263	PTS System
LacP0761_RS14850	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LacP0761_RS14855	COG0698	ribose 5-phosphate isomerase
LacP0761_RS14860	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
LacP0761_RS14865	COG1263	PTS System
LacP0761_RS14865	COG2190	(PTS) system
LacP0761_RS14865	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LacP0761_RS14885	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
LacP0761_RS14900	COG3716	PTS system mannose fructose sorbose family IID component
LacP0761_RS14905	COG3715	PTS system
LacP0761_RS14910	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LacP0761_RS14915	COG2222	sugar isomerase
LacP0761_RS14925	COG2222	sugar isomerase
LacP0761_RS14930	COG2188	Transcriptional regulator
LacP0761_RS14945	COG2801	Transposase and inactivated derivatives
LacP0761_RS14980	COG2801	Transposase and inactivated derivatives
LacP0761_RS14985	COG0662	Cupin 2, conserved barrel domain protein
LacP0761_RS15005	COG3843	relaxase mobilization nuclease domain protein
LacP0761_RS15095	COG0776	regulation of translation
LacP0761_RS15155	COG1192	Involved in chromosome partitioning
LacP0761_RS15170	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
LacP0761_RS15185	COG2826	transposase and inactivated derivatives, IS30 family
LacP0761_RS15200	COG0561	phosphatase activity
LacP0761_RS15205	COG1830	Aldolase
LacP0761_RS15210	COG1879	ABC-type sugar transport system periplasmic component
LacP0761_RS15235	COG1070	Carbohydrate kinase
LacP0761_RS15280	COG4282	regulation of fungal-type cell wall biogenesis