locus-tag	class	description
JIO02_RS00010	COG0592	DNA-directed DNA polymerase activity
JIO02_RS00020	COG2501	S4 domain
JIO02_RS00030	COG0187	DNA topoisomerase II activity
JIO02_RS00055	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
JIO02_RS00070	COG0629	single-stranded DNA binding
JIO02_RS00080	COG0693	protein deglycase activity
JIO02_RS00085	COG1271	oxidase subunit
JIO02_RS00090	COG1294	oxidase, subunit
JIO02_RS00105	COG1266	CAAX protease self-immunity
JIO02_RS00115	COG4555	ABC transporter
JIO02_RS00120	COG0004	ammonium transporteR
JIO02_RS00140	COG1136	(ABC) transporter
JIO02_RS00140	COG0577	efflux transmembrane transporter activity
JIO02_RS00150	COG0561	phosphatase activity
JIO02_RS00170	COG0110	maltose O-acetyltransferase activity
JIO02_RS00200	COG3409	Peptidoglycan-binding domain 1 protein
JIO02_RS00215	COG3250	beta-galactosidase activity
JIO02_RS00225	COG0800	Aldolase
JIO02_RS00230	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
JIO02_RS00235	COG1904	glucuronate isomerase
JIO02_RS00240	COG1312	Catalyzes the dehydration of D-mannonate
JIO02_RS00245	COG0246	Mannitol dehydrogenase
JIO02_RS00285	COG2814	Major facilitator Superfamily
JIO02_RS00305	COG1033	growth of symbiont in host cell
JIO02_RS00305	COG2409	Drug exporters of the RND superfamily
JIO02_RS00310	COG1309	transcriptional regulator
JIO02_RS00365	COG2217	Heavy metal translocating P-type atpase
JIO02_RS00375	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
JIO02_RS00390	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JIO02_RS00390	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
JIO02_RS00390	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JIO02_RS00395	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JIO02_RS00395	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
JIO02_RS00395	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JIO02_RS00400	COG0383	alpha-mannosidase activity
JIO02_RS00410	COG2723	6-phospho-beta-galactosidase activity
JIO02_RS00415	COG1940	carbohydrate kinase activity
JIO02_RS00425	COG0159	tryptophan synthase activity
JIO02_RS00475	COG1131	(ABC) transporter
JIO02_RS00490	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
JIO02_RS00510	COG0019	diaminopimelate decarboxylase activity
JIO02_RS00515	COG0527	aspartate kinase activity
JIO02_RS00525	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
JIO02_RS00535	COG0494	nUDIX hydrolase
JIO02_RS00550	COG3328	transposase activity
JIO02_RS00575	COG1131	(ABC) transporter
JIO02_RS00590	COG0305	Participates in initiation and elongation during chromosome replication
JIO02_RS00605	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
JIO02_RS00620	COG1309	transcriptional regulator
JIO02_RS00625	COG1136	(ABC) transporter
JIO02_RS00625	COG0577	efflux transmembrane transporter activity
JIO02_RS00645	COG2217	Heavy metal translocating P-type atpase
JIO02_RS00650	COG0640	Transcriptional regulator
JIO02_RS00660	COG3620	sequence-specific DNA binding
JIO02_RS00670	COG1131	(ABC) transporter
JIO02_RS00735	COG2814	Major facilitator Superfamily
JIO02_RS00745	COG2205	protein histidine kinase activity
JIO02_RS00750	COG0745	RESPONSE REGULATOR receiver
JIO02_RS00755	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
JIO02_RS00765	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
JIO02_RS00770	COG1447	Phosphotransferase system cellobiose-specific component IIA
JIO02_RS00780	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
JIO02_RS00785	COG2723	6-phospho-beta-galactosidase activity
JIO02_RS00790	COG2188	Transcriptional regulator
JIO02_RS00810	COG2252	PERMEase
JIO02_RS00820	COG0346	lactoylglutathione lyase activity
JIO02_RS00875	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
JIO02_RS00890	COG1070	Carbohydrate kinase
JIO02_RS00895	COG0191	fructose-bisphosphate aldolase activity
JIO02_RS00905	COG3328	transposase activity
JIO02_RS00925	COG0477	Major facilitator Superfamily
JIO02_RS00950	COG1131	(ABC) transporter
JIO02_RS00965	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
JIO02_RS00970	COG4166	transmembrane transport
JIO02_RS00980	COG3328	transposase activity
JIO02_RS01000	COG3328	transposase activity
JIO02_RS01010	COG1131	(ABC) transporter
JIO02_RS01035	COG0446	pyridine nucleotide-disulphide oxidoreductase
JIO02_RS01075	COG0716	FMN binding
JIO02_RS01090	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
JIO02_RS01100	COG2261	transglycosylase associated protein
JIO02_RS01115	COG1302	Protein conserved in bacteria
JIO02_RS01155	COG3442	glutamine amidotransferase
JIO02_RS01175	COG1192	Involved in chromosome partitioning
JIO02_RS01180	COG1475	DNA binding
JIO02_RS01185	COG4481	Protein conserved in bacteria
JIO02_RS01190	COG0012	GTP binding
JIO02_RS01200	COG0516	GMP reductase activity
JIO02_RS01200	COG0517	IMP dehydrogenase activity
JIO02_RS01220	COG1686	Belongs to the peptidase S11 family
JIO02_RS01225	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
JIO02_RS01235	COG1794	racemase activity, acting on amino acids and derivatives
JIO02_RS01240	COG0656	L-ascorbic acid biosynthetic process
JIO02_RS01245	COG1349	DNA-binding transcription factor activity
JIO02_RS01250	COG2814	Major facilitator Superfamily
JIO02_RS01255	COG1012	belongs to the aldehyde dehydrogenase family
JIO02_RS01260	COG3718	enzyme involved in inositol metabolism
JIO02_RS01265	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
JIO02_RS01270	COG3962	Belongs to the TPP enzyme family
JIO02_RS01275	COG0673	inositol 2-dehydrogenase activity
JIO02_RS01280	COG0673	inositol 2-dehydrogenase activity
JIO02_RS01290	COG0191	fructose-bisphosphate aldolase activity
JIO02_RS01295	COG1942	4-Oxalocrotonate Tautomerase
JIO02_RS01305	COG1082	Xylose isomerase domain protein TIM barrel
JIO02_RS01310	COG1737	Transcriptional regulator
JIO02_RS01315	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
JIO02_RS01325	COG2610	gluconate transmembrane transporter activity
JIO02_RS01330	COG3328	transposase activity
JIO02_RS01340	COG1121	(ABC) transporter
JIO02_RS01355	COG2084	Dehydrogenase
JIO02_RS01360	COG1164	Oligoendopeptidase f
JIO02_RS01365	COG1316	TRANSCRIPTIONal
JIO02_RS01370	COG1114	Component of the transport system for branched-chain amino acids
JIO02_RS01385	COG1216	Glycosyl transferase, family 2
JIO02_RS01410	COG0488	(ABC) transporter
JIO02_RS01435	COG3118	belongs to the thioredoxin family
JIO02_RS01470	COG0410	ABC transporter
JIO02_RS01475	COG1694	Mazg nucleotide pyrophosphohydrolase
JIO02_RS01490	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
JIO02_RS01495	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
JIO02_RS01510	COG0446	pyridine nucleotide-disulphide oxidoreductase
JIO02_RS01515	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
JIO02_RS01515	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
JIO02_RS01520	COG3711	transcriptional antiterminator
JIO02_RS01525	COG1447	Phosphotransferase system cellobiose-specific component IIA
JIO02_RS01530	COG2723	6-phospho-beta-galactosidase activity
JIO02_RS01550	COG2182	Extracellular solute-binding protein
JIO02_RS01560	COG3711	transcriptional antiterminator
JIO02_RS01560	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
JIO02_RS01570	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JIO02_RS01570	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JIO02_RS01570	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
JIO02_RS01575	COG1482	cell wall glycoprotein biosynthetic process
JIO02_RS01580	COG2188	Transcriptional regulator
JIO02_RS01585	COG2222	sugar isomerase
JIO02_RS01600	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JIO02_RS01605	COG3715	PTS system
JIO02_RS01610	COG3716	PTS system mannose fructose sorbose family IID component
JIO02_RS01615	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JIO02_RS01615	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
JIO02_RS01635	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
JIO02_RS01640	COG0006	proline dipeptidase activity
JIO02_RS01650	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
JIO02_RS01660	COG1363	Peptidase, m42
JIO02_RS01670	COG2195	Cleaves the N-terminal amino acid of tripeptides
JIO02_RS01675	COG4166	transmembrane transport
JIO02_RS01710	COG1122	ATPase activity
JIO02_RS01720	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
JIO02_RS01740	COG0351	phosphomethylpyrimidine kinase
JIO02_RS01745	COG0531	amino acid
JIO02_RS01750	COG1609	Transcriptional regulator
JIO02_RS01765	COG1172	Belongs to the binding-protein-dependent transport system permease family
JIO02_RS01770	COG1879	ABC-type sugar transport system periplasmic component
JIO02_RS01780	COG1598	PFAM Uncharacterised protein family UPF0150
JIO02_RS01790	COG3328	transposase activity
JIO02_RS01830	COG1131	(ABC) transporter
JIO02_RS01870	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
JIO02_RS01905	COG3069	C4-dicarboxylate transmembrane transporter activity
JIO02_RS01915	COG2188	Transcriptional regulator
JIO02_RS01930	COG1070	Carbohydrate kinase
JIO02_RS01935	COG1028	Short-chain dehydrogenase reductase Sdr
JIO02_RS01940	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
JIO02_RS01955	COG3711	transcriptional antiterminator
JIO02_RS01960	COG0191	fructose-bisphosphate aldolase activity
JIO02_RS01965	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
JIO02_RS01965	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JIO02_RS01965	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JIO02_RS01995	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
JIO02_RS02000	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JIO02_RS02005	COG3715	PTS system
JIO02_RS02010	COG3716	PTS system mannose fructose sorbose family IID component
JIO02_RS02020	COG0471	metal ion transport
JIO02_RS02025	COG0445	tRNA wobble uridine modification
JIO02_RS02030	COG0583	DNA-binding transcription factor activity
JIO02_RS02045	COG1122	ATPase activity
JIO02_RS02055	COG1609	Transcriptional regulator
JIO02_RS02060	COG2211	Major facilitator Superfamily
JIO02_RS02070	COG1053	succinate dehydrogenase
JIO02_RS02080	COG3775	system Galactitol-specific IIC component
JIO02_RS02095	COG1349	DNA-binding transcription factor activity
JIO02_RS02130	COG0561	phosphatase activity
JIO02_RS02135	COG3328	transposase activity
JIO02_RS02145	COG1263	PTS System
JIO02_RS02145	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JIO02_RS02150	COG1737	Transcriptional regulator
JIO02_RS02160	COG1263	PTS System
JIO02_RS02160	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JIO02_RS02165	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JIO02_RS02165	COG1263	PTS System
JIO02_RS02165	COG2190	(PTS) system
JIO02_RS02175	COG3711	transcriptional antiterminator
JIO02_RS02180	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JIO02_RS02180	COG2190	(PTS) system
JIO02_RS02180	COG1263	PTS System
JIO02_RS02185	COG2723	6-phospho-beta-galactosidase activity
JIO02_RS02190	COG3711	transcriptional antiterminator
JIO02_RS02205	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JIO02_RS02205	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JIO02_RS02205	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
JIO02_RS02210	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JIO02_RS02215	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JIO02_RS02215	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
JIO02_RS02215	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JIO02_RS02250	COG3394	polysaccharide catabolic process
JIO02_RS02255	COG1486	melibiose metabolic process
JIO02_RS02260	COG1737	Transcriptional regulator
JIO02_RS02265	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
JIO02_RS02265	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JIO02_RS02265	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JIO02_RS02270	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JIO02_RS02270	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JIO02_RS02275	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
JIO02_RS02295	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
JIO02_RS02320	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
JIO02_RS02330	COG2213	PTS system mannitol-specific
JIO02_RS02330	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
JIO02_RS02360	COG3942	CHAP domain
JIO02_RS02375	COG1136	(ABC) transporter
JIO02_RS02380	COG0446	pyridine nucleotide-disulphide oxidoreductase
JIO02_RS02385	COG0561	phosphatase activity
JIO02_RS02395	COG1609	Transcriptional regulator
JIO02_RS02400	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JIO02_RS02410	COG3716	PTS system mannose fructose sorbose family IID component
JIO02_RS02425	COG0366	Alpha amylase catalytic
JIO02_RS02450	COG1464	Belongs to the NlpA lipoprotein family
JIO02_RS02455	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
JIO02_RS02475	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
JIO02_RS02480	COG1461	Dihydroxyacetone kinase
JIO02_RS02485	COG2376	Dihydroxyacetone kinase
JIO02_RS02540	COG2814	Major facilitator Superfamily
JIO02_RS02570	COG0028	Belongs to the TPP enzyme family
JIO02_RS02585	COG4948	Mandelate Racemase Muconate Lactonizing
JIO02_RS02590	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
JIO02_RS02595	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
JIO02_RS02635	COG0789	Transcriptional regulator
JIO02_RS02640	COG0656	L-ascorbic acid biosynthetic process
JIO02_RS02645	COG0604	alcohol dehydrogenase
JIO02_RS02650	COG1733	regulation of RNA biosynthetic process
JIO02_RS02665	COG1131	(ABC) transporter
JIO02_RS02685	COG1131	(ABC) transporter
JIO02_RS02700	COG0308	aminopeptidase N
JIO02_RS02705	COG0531	amino acid
JIO02_RS02720	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
JIO02_RS02745	COG0626	cystathionine gamma-synthase activity
JIO02_RS02750	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JIO02_RS02755	COG0765	amino acid transport
JIO02_RS02765	COG1114	Component of the transport system for branched-chain amino acids
JIO02_RS02810	COG0697	spore germination
JIO02_RS02820	COG1131	(ABC) transporter
JIO02_RS02835	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
JIO02_RS02840	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
JIO02_RS02845	COG1132	(ABC) transporter
JIO02_RS02850	COG1132	(ABC) transporter
JIO02_RS02860	COG2188	Transcriptional regulator
JIO02_RS02865	COG0366	Alpha amylase catalytic
JIO02_RS02870	COG2190	(PTS) system
JIO02_RS02870	COG1263	PTS System
JIO02_RS02870	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JIO02_RS02875	COG3328	transposase activity
JIO02_RS02885	COG0531	amino acid
JIO02_RS02890	COG0039	L-malate dehydrogenase activity
JIO02_RS02895	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
JIO02_RS02900	COG1278	Cold shock
JIO02_RS02915	COG0488	(ABC) transporter
JIO02_RS02920	COG0702	epimerase
JIO02_RS02925	COG0656	L-ascorbic acid biosynthetic process
JIO02_RS02930	COG1113	amino acid transport
JIO02_RS02970	COG3338	carbonate dehydratase activity
JIO02_RS02980	COG2816	NAD+ diphosphatase activity
JIO02_RS02990	COG0004	ammonium transporteR
JIO02_RS03000	COG1285	pathogenesis
JIO02_RS03010	COG0488	(ABC) transporter
JIO02_RS03015	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
JIO02_RS03020	COG1573	uracil-dna glycosylase
JIO02_RS03025	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
JIO02_RS03030	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
JIO02_RS03035	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
JIO02_RS03040	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
JIO02_RS03040	COG1215	transferase activity, transferring glycosyl groups
JIO02_RS03045	COG3711	transcriptional antiterminator
JIO02_RS03050	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
JIO02_RS03050	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
JIO02_RS03055	COG2723	6-phospho-beta-galactosidase activity
JIO02_RS03060	COG1447	Phosphotransferase system cellobiose-specific component IIA
JIO02_RS03070	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
JIO02_RS03080	COG1609	Transcriptional regulator
JIO02_RS03085	COG2017	converts alpha-aldose to the beta-anomer
JIO02_RS03105	COG3775	system Galactitol-specific IIC component
JIO02_RS03130	COG3684	Belongs to the aldolase LacD family
JIO02_RS03145	COG1349	DNA-binding transcription factor activity
JIO02_RS03155	COG0420	3'-5' exonuclease activity
JIO02_RS03160	COG0419	ATPase involved in DNA repair
JIO02_RS03175	COG1194	a g-specific adenine glycosylase
JIO02_RS03185	COG2249	NAD(P)H dehydrogenase (quinone) activity
JIO02_RS03200	COG0351	phosphomethylpyrimidine kinase
JIO02_RS03215	COG2910	NAD(P)H-binding
JIO02_RS03220	COG3328	transposase activity
JIO02_RS03225	COG1472	Belongs to the glycosyl hydrolase 3 family
JIO02_RS03240	COG4120	Belongs to the binding-protein-dependent transport system permease family
JIO02_RS03250	COG0604	alcohol dehydrogenase
JIO02_RS03260	COG0463	Glycosyl transferase, family 2
JIO02_RS03265	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
JIO02_RS03275	COG0745	RESPONSE REGULATOR receiver
JIO02_RS03280	COG5002	protein histidine kinase activity
JIO02_RS03290	COG3328	transposase activity
JIO02_RS03295	COG0778	Nitroreductase
JIO02_RS03300	COG1304	FMN binding
JIO02_RS03390	COG4695	Portal protein
JIO02_RS03445	COG0604	alcohol dehydrogenase
JIO02_RS03460	COG0628	permease
JIO02_RS03485	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
JIO02_RS03495	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
JIO02_RS03500	COG3189	MarR family transcriptional regulator
JIO02_RS03530	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
JIO02_RS03555	COG0105	UTP biosynthetic process
JIO02_RS03565	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
JIO02_RS03570	COG2267	carboxylic ester hydrolase activity
JIO02_RS03605	COG2267	carboxylic ester hydrolase activity
JIO02_RS03640	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
JIO02_RS03665	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
JIO02_RS03670	COG0343	queuine tRNA-ribosyltransferase activity
JIO02_RS03675	COG1862	Preprotein translocase
JIO02_RS03680	COG1012	belongs to the aldehyde dehydrogenase family
JIO02_RS03680	COG1454	alcohol dehydrogenase
JIO02_RS03690	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
JIO02_RS03700	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
JIO02_RS03705	COG4109	DRTGG domain
JIO02_RS03710	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
JIO02_RS03715	COG0513	Belongs to the DEAD box helicase family
JIO02_RS03770	COG3118	belongs to the thioredoxin family
JIO02_RS03780	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
JIO02_RS03785	COG1696	Membrane protein involved in D-alanine export
JIO02_RS03790	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
JIO02_RS03795	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
JIO02_RS03800	COG1719	4-vinyl reductase, 4VR
JIO02_RS03805	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
JIO02_RS03815	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
JIO02_RS03830	COG0668	transmembrane transport
JIO02_RS03845	COG1827	regulation of RNA biosynthetic process
JIO02_RS03850	COG0006	proline dipeptidase activity
JIO02_RS03855	COG1609	Transcriptional regulator
JIO02_RS03860	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
JIO02_RS03865	COG1011	Hydrolase
JIO02_RS03905	COG0737	Belongs to the 5'-nucleotidase family
JIO02_RS03910	COG4470	Protein conserved in bacteria
JIO02_RS03915	COG0647	UMP catabolic process
JIO02_RS03925	COG3328	transposase activity
JIO02_RS03935	COG0586	Pfam SNARE associated Golgi protein
JIO02_RS03940	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
JIO02_RS03955	COG1098	S1 RNA binding domain
JIO02_RS04110	COG0531	amino acid
JIO02_RS04115	COG0438	transferase activity, transferring glycosyl groups
JIO02_RS04120	COG0438	transferase activity, transferring glycosyl groups
JIO02_RS04130	COG0436	Aminotransferase
JIO02_RS04140	COG1368	sulfuric ester hydrolase activity
JIO02_RS04145	COG0735	belongs to the Fur family
JIO02_RS04255	COG0305	Participates in initiation and elongation during chromosome replication
JIO02_RS04270	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
JIO02_RS04315	COG3328	transposase activity
JIO02_RS04505	COG0477	Major facilitator Superfamily
JIO02_RS04515	COG2814	Major facilitator Superfamily
JIO02_RS04525	COG0671	phosphoesterase, PA-phosphatase related
JIO02_RS04535	COG2244	polysaccharide biosynthetic process
JIO02_RS04540	COG1187	pseudouridine synthase activity
JIO02_RS04550	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
JIO02_RS04570	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
JIO02_RS04580	COG3830	Belongs to the UPF0237 family
JIO02_RS04605	COG2357	RelA SpoT domain protein
JIO02_RS04615	COG0564	pseudouridine synthase activity
JIO02_RS04625	COG3142	Participates in the control of copper homeostasis
JIO02_RS04635	COG2706	6-phosphogluconolactonase activity
JIO02_RS04645	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
JIO02_RS04665	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
JIO02_RS04675	COG1674	ftsk spoiiie
JIO02_RS04680	COG0612	Peptidase, M16
JIO02_RS04685	COG0612	Peptidase, M16
JIO02_RS04690	COG1028	Short-chain dehydrogenase reductase Sdr
JIO02_RS04695	COG1426	Protein conserved in bacteria
JIO02_RS04700	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
JIO02_RS04710	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
JIO02_RS04720	COG1739	Uncharacterized protein family UPF0029
JIO02_RS04725	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
JIO02_RS04755	COG2884	Cell division ATP-binding protein ftsE
JIO02_RS04760	COG2177	Part of the ABC transporter FtsEX involved in
JIO02_RS04770	COG0745	RESPONSE REGULATOR receiver
JIO02_RS04775	COG5002	protein histidine kinase activity
JIO02_RS04785	COG0573	inorganic phosphate transmembrane transporter activity
JIO02_RS04790	COG0581	inorganic phosphate transmembrane transporter activity
JIO02_RS04795	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
JIO02_RS04800	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
JIO02_RS04805	COG0704	Plays a role in the regulation of phosphate uptake
JIO02_RS04820	COG1950	PFAM Membrane protein of
JIO02_RS04830	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
JIO02_RS04840	COG0492	ferredoxin-NADP+ reductase activity
JIO02_RS04845	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
JIO02_RS04850	COG0745	RESPONSE REGULATOR receiver
JIO02_RS04860	COG0577	efflux transmembrane transporter activity
JIO02_RS04860	COG1136	(ABC) transporter
JIO02_RS04880	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
JIO02_RS04895	COG0391	Required for morphogenesis under gluconeogenic growth conditions
JIO02_RS04905	COG1846	Transcriptional regulator
JIO02_RS04920	COG2390	Transcriptional regulator
JIO02_RS04960	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
JIO02_RS04970	COG0557	exoribonuclease II activity
JIO02_RS04990	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
JIO02_RS05020	COG0395	ABC-type sugar transport system, permease component
JIO02_RS05025	COG1175	transmembrane transport
JIO02_RS05030	COG3842	ATPase activity
JIO02_RS05045	COG0561	phosphatase activity
JIO02_RS05055	COG0280	phosphate acetyltransferase
JIO02_RS05060	COG0802	atpase or kinase
JIO02_RS05065	COG4152	abc transporter atp-binding protein
JIO02_RS05070	COG1668	transmembrane transport
JIO02_RS05080	COG0708	Exodeoxyribonuclease III
JIO02_RS05085	COG0812	UDP-N-acetylmuramate dehydrogenase activity
JIO02_RS05095	COG1396	sequence-specific DNA binding
JIO02_RS05095	COG3800	Transcriptional regulator
JIO02_RS05105	COG1176	ABC-type spermidine putrescine transport system, permease component I
JIO02_RS05110	COG1177	transmembrane transport
JIO02_RS05115	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
JIO02_RS05120	COG3328	transposase activity
JIO02_RS05140	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
JIO02_RS05145	COG1309	transcriptional regulator
JIO02_RS05175	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
JIO02_RS05195	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
JIO02_RS05200	COG1459	type II secretion system
JIO02_RS05230	COG0827	DNA restriction-modification system
JIO02_RS05240	COG1113	amino acid transport
JIO02_RS05265	COG3328	transposase activity
JIO02_RS05345	COG4695	Portal protein
JIO02_RS05375	COG2261	transglycosylase associated protein
JIO02_RS05390	COG0745	RESPONSE REGULATOR receiver
JIO02_RS05395	COG5002	protein histidine kinase activity
JIO02_RS05395	COG3850	Histidine kinase
JIO02_RS05425	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
JIO02_RS05485	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
JIO02_RS05490	COG2814	Major facilitator Superfamily
JIO02_RS05495	COG0561	phosphatase activity
JIO02_RS05500	COG2326	polyphosphate kinase activity
JIO02_RS05545	COG0673	inositol 2-dehydrogenase activity
JIO02_RS05555	COG1447	Phosphotransferase system cellobiose-specific component IIA
JIO02_RS05580	COG0514	ATP-dependent DNA helicase (RecQ)
JIO02_RS05585	COG2309	aminopeptidase activity
JIO02_RS05600	COG1295	ribonuclease BN
JIO02_RS05605	COG0716	FMN binding
JIO02_RS05610	COG0024	Methionine aminopeptidase
JIO02_RS05615	COG0463	Glycosyl transferase, family 2
JIO02_RS05635	COG1210	Utp--glucose-1-phosphate uridylyltransferase
JIO02_RS05640	COG1216	Glycosyl transferase, family 2
JIO02_RS05640	COG1442	glycosyl transferase family 8
JIO02_RS05645	COG1442	glycosyl transferase family 8
JIO02_RS05655	COG0653	protein targeting
JIO02_RS05660	COG2723	6-phospho-beta-galactosidase activity
JIO02_RS05665	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JIO02_RS05665	COG2190	(PTS) system
JIO02_RS05665	COG1263	PTS System
JIO02_RS05670	COG4485	Bacterial membrane protein, YfhO
JIO02_RS05685	COG0463	Glycosyl transferase, family 2
JIO02_RS05695	COG4129	membrane
JIO02_RS05700	COG1278	Cold shock
JIO02_RS05715	COG1705	Flagellar rod assembly protein muramidase FlgJ
JIO02_RS05730	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
JIO02_RS05735	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
JIO02_RS05750	COG1368	sulfuric ester hydrolase activity
JIO02_RS05765	COG4975	Glucose uptake
JIO02_RS05775	COG0582	viral genome integration into host DNA
JIO02_RS05815	COG1396	sequence-specific DNA binding
JIO02_RS05860	COG0629	single-stranded DNA binding
JIO02_RS05890	COG4974	Belongs to the 'phage' integrase family
JIO02_RS06000	COG3328	transposase activity
JIO02_RS06115	COG0590	tRNA wobble adenosine to inosine editing
JIO02_RS06125	COG3328	transposase activity
JIO02_RS06150	COG2814	Major facilitator Superfamily
JIO02_RS06185	COG0588	phosphoglycerate mutase activity
JIO02_RS06210	COG2514	catechol 2,3-dioxygenase activity
JIO02_RS06215	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
JIO02_RS06220	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
JIO02_RS06225	COG1435	thymidine kinase activity
JIO02_RS06235	COG2890	protein-(glutamine-N5) methyltransferase activity
JIO02_RS06240	COG0009	L-threonylcarbamoyladenylate synthase
JIO02_RS06255	COG0356	it plays a direct role in the translocation of protons across the membrane
JIO02_RS06300	COG1077	Cell shape determining protein MreB Mrl
JIO02_RS06320	COG0772	Belongs to the SEDS family
JIO02_RS06325	COG0509	glycine decarboxylation via glycine cleavage system
JIO02_RS06330	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
JIO02_RS06335	COG1464	Belongs to the NlpA lipoprotein family
JIO02_RS06350	COG2011	ABC-type metal ion transport system permease component
JIO02_RS06360	COG0719	Fe-S assembly protein
JIO02_RS06365	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
JIO02_RS06370	COG0822	iron-sulfur transferase activity
JIO02_RS06375	COG0719	Fe-S assembly protein
JIO02_RS06410	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
JIO02_RS06415	COG2918	glutathione biosynthetic process
JIO02_RS06415	COG1181	Belongs to the D-alanine--D-alanine ligase family
JIO02_RS06420	COG5506	Protein of unknown function (DUF1694)
JIO02_RS06430	COG1760	l-serine dehydratase
JIO02_RS06435	COG1760	l-serine dehydratase
JIO02_RS06445	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
JIO02_RS06450	COG1028	Short-chain dehydrogenase reductase Sdr
JIO02_RS06460	COG1428	Deoxynucleoside kinase
JIO02_RS06470	COG4166	transmembrane transport
JIO02_RS06475	COG2205	protein histidine kinase activity
JIO02_RS06480	COG0745	RESPONSE REGULATOR receiver
JIO02_RS06525	COG1307	EDD domain protein, DegV family
JIO02_RS06535	COG2197	response regulator
JIO02_RS06540	COG4585	Histidine kinase
JIO02_RS06550	COG1131	(ABC) transporter
JIO02_RS06575	COG2183	response to ionizing radiation
JIO02_RS06580	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
JIO02_RS06615	COG1956	GAF domain-containing protein
JIO02_RS06620	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
JIO02_RS06630	COG1104	cysteine desulfurase activity
JIO02_RS06640	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
JIO02_RS06650	COG0525	valine-tRNA ligase activity
JIO02_RS06665	COG2003	Belongs to the UPF0758 family
JIO02_RS06670	COG1077	Cell shape determining protein MreB Mrl
JIO02_RS06675	COG1792	Involved in formation and maintenance of cell shape
JIO02_RS06685	COG0850	regulation of cytokinetic process
JIO02_RS06690	COG2894	cell division
JIO02_RS06695	COG0765	amino acid transport
JIO02_RS06700	COG1126	abc transporter atp-binding protein
JIO02_RS06705	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JIO02_RS06715	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
JIO02_RS06730	COG2001	Belongs to the MraZ family
JIO02_RS06745	COG0768	penicillin binding
JIO02_RS06770	COG0849	cell division
JIO02_RS06785	COG0762	integral membrane protein
JIO02_RS06795	COG3599	regulation of cell shape
JIO02_RS06805	COG1278	Cold shock
JIO02_RS06815	COG2814	Major facilitator Superfamily
JIO02_RS06820	COG3853	Toxic anion resistance protein (TelA)
JIO02_RS06845	COG1104	cysteine desulfurase activity
JIO02_RS06855	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
JIO02_RS06875	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
JIO02_RS06885	COG1597	lipid kinase activity
JIO02_RS06925	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
JIO02_RS06950	COG4476	Belongs to the UPF0223 family
JIO02_RS06955	COG0483	inositol monophosphate 1-phosphatase activity
JIO02_RS06960	COG1217	gtp-binding protein TYPA
JIO02_RS06970	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
JIO02_RS06975	COG4471	UPF0298 protein
JIO02_RS06980	COG0742	ribosomal rna small subunit methyltransferase
JIO02_RS06990	COG3480	Lon protease (S16) C-terminal proteolytic domain
JIO02_RS07000	COG2333	competence protein COMEC
JIO02_RS07000	COG0658	competence protein
JIO02_RS07005	COG1466	dna polymerase III delta subunit
JIO02_RS07045	COG3328	transposase activity
JIO02_RS07070	COG1132	(ABC) transporter
JIO02_RS07080	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
JIO02_RS07105	COG0765	amino acid transport
JIO02_RS07110	COG1126	abc transporter atp-binding protein
JIO02_RS07120	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JIO02_RS07120	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JIO02_RS07120	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
JIO02_RS07125	COG1105	Belongs to the carbohydrate kinase PfkB family
JIO02_RS07130	COG1349	DNA-binding transcription factor activity
JIO02_RS07140	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
JIO02_RS07140	COG2755	lipolytic protein G-D-S-L family
JIO02_RS07150	COG0300	oxidoreductase activity
JIO02_RS07155	COG5416	Lipopolysaccharide assembly protein A domain
JIO02_RS07160	COG0542	response to heat
JIO02_RS07175	COG0737	Belongs to the 5'-nucleotidase family
JIO02_RS07190	COG0587	DNA-directed DNA polymerase activity
JIO02_RS07210	COG2996	Protein conserved in bacteria
JIO02_RS07225	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
JIO02_RS07230	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
JIO02_RS07235	COG1187	pseudouridine synthase activity
JIO02_RS07240	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
JIO02_RS07255	COG0514	ATP-dependent DNA helicase (RecQ)
JIO02_RS07270	COG0539	negative regulation of cytoplasmic translation
JIO02_RS07295	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
JIO02_RS07310	COG0488	(ABC) transporter
JIO02_RS07315	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
JIO02_RS07325	COG1272	protein, Hemolysin III
JIO02_RS07330	COG1307	EDD domain protein, DegV family
JIO02_RS07335	COG2755	lipolytic protein G-D-S-L family
JIO02_RS07340	COG4698	Protein conserved in bacteria
JIO02_RS07345	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
JIO02_RS07355	COG0793	Belongs to the peptidase S41A family
JIO02_RS07355	COG3409	Peptidoglycan-binding domain 1 protein
JIO02_RS07395	COG0758	DNA mediated transformation
JIO02_RS07400	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
JIO02_RS07420	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
JIO02_RS07435	COG0187	DNA topoisomerase II activity
JIO02_RS07440	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
JIO02_RS07450	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
JIO02_RS07455	COG0583	DNA-binding transcription factor activity
JIO02_RS07460	COG1227	inorganic diphosphatase activity
JIO02_RS07465	COG4974	Belongs to the 'phage' integrase family
JIO02_RS07470	COG0577	efflux transmembrane transporter activity
JIO02_RS07475	COG1136	(ABC) transporter
JIO02_RS07480	COG5002	protein histidine kinase activity
JIO02_RS07485	COG0745	RESPONSE REGULATOR receiver
JIO02_RS07505	COG0778	Nitroreductase
JIO02_RS07515	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
JIO02_RS07550	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
JIO02_RS07565	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
JIO02_RS07575	COG1307	EDD domain protein, DegV family
JIO02_RS07585	COG1293	RNA-binding protein homologous to eukaryotic snRNP
JIO02_RS07600	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
JIO02_RS07605	COG0284	orotidine-5'-phosphate decarboxylase activity
JIO02_RS07620	COG0505	Belongs to the CarA family
JIO02_RS07625	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
JIO02_RS07635	COG2233	PERMEase
JIO02_RS07640	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
JIO02_RS07645	COG0564	pseudouridine synthase activity
JIO02_RS07650	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
JIO02_RS07665	COG0328	RNA-DNA hybrid ribonuclease activity
JIO02_RS07675	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
JIO02_RS07695	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
JIO02_RS07700	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
JIO02_RS07705	COG0583	DNA-binding transcription factor activity
JIO02_RS07710	COG3590	peptidase
JIO02_RS07715	COG0095	Lipoate-protein ligase
JIO02_RS07730	COG0116	Belongs to the methyltransferase superfamily
JIO02_RS07755	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
JIO02_RS07760	COG2131	deaminase
JIO02_RS07765	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
JIO02_RS07780	COG0436	Aminotransferase
JIO02_RS07790	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
JIO02_RS07790	COG1199	ATP-dependent helicase activity
JIO02_RS07805	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
JIO02_RS07820	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
JIO02_RS07820	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
JIO02_RS07835	COG2151	metal-sulfur cluster biosynthetic enzyme
JIO02_RS07840	COG1942	4-Oxalocrotonate Tautomerase
JIO02_RS07850	COG2274	protein secretion by the type I secretion system
JIO02_RS07850	COG3271	cysteine-type peptidase activity
JIO02_RS07855	COG3842	ATPase activity
JIO02_RS07860	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
JIO02_RS07865	COG2384	SAM-dependent methyltransferase
JIO02_RS07870	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
JIO02_RS07875	COG0358	DNA primase activity
JIO02_RS07910	COG1381	Involved in DNA repair and RecF pathway recombination
JIO02_RS07920	COG0295	cytidine deaminase activity
JIO02_RS07935	COG1702	phosphate starvation-inducible protein PhoH
JIO02_RS07955	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
JIO02_RS07960	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
JIO02_RS07965	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
JIO02_RS07985	COG4991	sh3 domain protein
JIO02_RS07985	COG3103	Sh3 type 3 domain protein
JIO02_RS07985	COG0860	N-Acetylmuramoyl-L-alanine amidase
JIO02_RS08000	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
JIO02_RS08010	COG1385	rRNA (uridine-N3-)-methyltransferase activity
JIO02_RS08025	COG2094	Belongs to the DNA glycosylase MPG family
JIO02_RS08060	COG1192	Involved in chromosome partitioning
JIO02_RS08065	COG1002	Type II restriction enzyme, methylase subunits
JIO02_RS08070	COG1598	PFAM Uncharacterised protein family UPF0150
JIO02_RS08090	COG2946	Replication initiation factor
JIO02_RS08095	COG0582	viral genome integration into host DNA
JIO02_RS08105	COG2249	NAD(P)H dehydrogenase (quinone) activity
JIO02_RS08120	COG0438	transferase activity, transferring glycosyl groups
JIO02_RS08170	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
JIO02_RS08180	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
JIO02_RS08180	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
JIO02_RS08215	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
JIO02_RS08225	COG0635	Involved in the biosynthesis of porphyrin-containing compound
JIO02_RS08230	COG0196	riboflavin kinase activity
JIO02_RS08240	COG0861	Integral membrane protein TerC family
JIO02_RS08245	COG3328	transposase activity
JIO02_RS08270	COG0195	Participates in both transcription termination and antitermination
JIO02_RS08290	COG0750	zinc metalloprotease
JIO02_RS08295	COG4589	Belongs to the CDS family
JIO02_RS08300	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
JIO02_RS08330	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
JIO02_RS08335	COG0204	Acyl-transferase
JIO02_RS08340	COG0531	amino acid
JIO02_RS08350	COG1132	(ABC) transporter
JIO02_RS08355	COG1132	(ABC) transporter
JIO02_RS08360	COG3763	UPF0154 protein
JIO02_RS08365	COG4224	UPF0291 protein
JIO02_RS08390	COG1837	Belongs to the UPF0109 family
JIO02_RS08400	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
JIO02_RS08420	COG0552	protein localization to endoplasmic reticulum
JIO02_RS08425	COG1196	nuclear chromosome segregation
JIO02_RS08430	COG0571	ribonuclease III activity
JIO02_RS08435	COG0747	negative chemotaxis
JIO02_RS08440	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
JIO02_RS08445	COG0601	transmembrane transport
JIO02_RS08450	COG4608	Belongs to the ABC transporter superfamily
JIO02_RS08460	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
JIO02_RS08470	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
JIO02_RS08475	COG1461	Dihydroxyacetone kinase
JIO02_RS08490	COG1564	THIamine pyrophosphokinase
JIO02_RS08495	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
JIO02_RS08500	COG1162	GTPase activity
JIO02_RS08505	COG2815	serine threonine protein kinase
JIO02_RS08505	COG0515	serine threonine protein kinase
JIO02_RS08515	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
JIO02_RS08515	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
JIO02_RS08525	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
JIO02_RS08530	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
JIO02_RS08540	COG0194	GDP metabolic process
JIO02_RS08555	COG0497	DNA recombination
JIO02_RS08560	COG1438	arginine binding
JIO02_RS08565	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
JIO02_RS08575	COG1722	exodeoxyribonuclease VII activity
JIO02_RS08595	COG1302	Protein conserved in bacteria
JIO02_RS08600	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
JIO02_RS08605	COG0006	proline dipeptidase activity
JIO02_RS08610	COG0211	Belongs to the bacterial ribosomal protein bL27 family
JIO02_RS08615	COG2868	ribosomal protein
JIO02_RS08620	COG0261	This protein binds to 23S rRNA in the presence of protein L20
JIO02_RS08645	COG2936	dipeptidyl-peptidase activity
JIO02_RS08655	COG0789	Transcriptional regulator
JIO02_RS08660	COG1982	Orn Lys Arg decarboxylase major
JIO02_RS08665	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
JIO02_RS08680	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
JIO02_RS08685	COG1940	carbohydrate kinase activity
JIO02_RS08695	COG0457	Tetratricopeptide repeat
JIO02_RS08695	COG0705	Rhomboid family
JIO02_RS08700	COG0768	penicillin binding
JIO02_RS08710	COG4841	protein insertion into membrane
JIO02_RS08715	COG2197	response regulator
JIO02_RS08720	COG4585	Histidine kinase
JIO02_RS08730	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
JIO02_RS08735	COG0572	uridine kinase
JIO02_RS08740	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
JIO02_RS08745	COG0072	phenylalanine-tRNA ligase activity
JIO02_RS08755	COG1733	regulation of RNA biosynthetic process
JIO02_RS08765	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
JIO02_RS08775	COG0706	membrane insertase activity
JIO02_RS08780	COG5002	protein histidine kinase activity
JIO02_RS08785	COG0745	RESPONSE REGULATOR receiver
JIO02_RS08790	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
JIO02_RS08805	COG2226	methyltransferase
JIO02_RS08810	COG0799	negative regulation of ribosome biogenesis
JIO02_RS08820	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
JIO02_RS08825	COG1534	Rna-binding protein
JIO02_RS08830	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
JIO02_RS08835	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
JIO02_RS08840	COG0346	lactoylglutathione lyase activity
JIO02_RS08850	COG0400	carboxylic ester hydrolase activity
JIO02_RS08875	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
JIO02_RS08895	COG1484	DNA-dependent DNA replication
JIO02_RS08910	COG0237	dephospho-CoA kinase activity
JIO02_RS08915	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
JIO02_RS08920	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
JIO02_RS08920	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
JIO02_RS08925	COG0670	Belongs to the BI1 family
JIO02_RS08960	COG1674	ftsk spoiiie
JIO02_RS08970	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
JIO02_RS08975	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
JIO02_RS09000	COG1131	(ABC) transporter
JIO02_RS09005	COG0537	adenosine 5'-monophosphoramidase activity
JIO02_RS09015	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
JIO02_RS09025	COG3481	metal-dependent phosphohydrolase, HD sub domain
JIO02_RS09035	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
JIO02_RS09040	COG0564	pseudouridine synthase activity
JIO02_RS09045	COG1438	arginine binding
JIO02_RS09050	COG0018	arginyl-trna synthetase
JIO02_RS09070	COG0167	dihydroorotate dehydrogenase activity
JIO02_RS09085	COG1393	Belongs to the ArsC family
JIO02_RS09090	COG1234	tRNA 3'-trailer cleavage
JIO02_RS09105	COG1136	(ABC) transporter
JIO02_RS09110	COG0745	RESPONSE REGULATOR receiver
JIO02_RS09115	COG0642	Histidine kinase
JIO02_RS09120	COG0602	queuosine metabolic process
JIO02_RS09130	COG3682	Transcriptional regulator
JIO02_RS09135	COG0151	Belongs to the GarS family
JIO02_RS09145	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
JIO02_RS09150	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
JIO02_RS09170	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
JIO02_RS09180	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
JIO02_RS09195	COG2814	Major facilitator Superfamily
JIO02_RS09205	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
JIO02_RS09215	COG0542	response to heat
JIO02_RS09230	COG1253	flavin adenine dinucleotide binding
JIO02_RS09235	COG0628	permease
JIO02_RS09240	COG2153	protein acetylation
JIO02_RS09250	COG3557	Belongs to the UPF0374 family
JIO02_RS09270	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
JIO02_RS09280	COG0028	Belongs to the TPP enzyme family
JIO02_RS09285	COG3425	synthase
JIO02_RS09295	COG0183	Belongs to the thiolase family
JIO02_RS09315	COG2017	converts alpha-aldose to the beta-anomer
JIO02_RS09320	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
JIO02_RS09340	COG3091	SprT-like family
JIO02_RS09345	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
JIO02_RS09350	COG4120	Belongs to the binding-protein-dependent transport system permease family
JIO02_RS09385	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
JIO02_RS09390	COG2188	Transcriptional regulator
JIO02_RS09395	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
JIO02_RS09400	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
JIO02_RS09405	COG4946	Tricorn protease homolog
JIO02_RS09405	COG1506	peptidase
JIO02_RS09405	COG0823	Involved in the tonB-independent uptake of proteins
JIO02_RS09450	COG3104	oligopeptide transport
JIO02_RS09455	COG1136	(ABC) transporter
JIO02_RS09455	COG0577	efflux transmembrane transporter activity
JIO02_RS09470	COG2211	Major facilitator Superfamily
JIO02_RS09505	COG2755	lipolytic protein G-D-S-L family
JIO02_RS09505	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
JIO02_RS09585	COG0833	amino acid
JIO02_RS09590	COG3527	Alpha-acetolactate decarboxylase
JIO02_RS09625	COG0564	pseudouridine synthase activity
JIO02_RS09690	COG3328	transposase activity
JIO02_RS09700	COG0511	ligase activity, forming carbon-carbon bonds
JIO02_RS09710	COG2851	Citrate transporter
JIO02_RS09745	COG0778	Nitroreductase
JIO02_RS09760	COG1309	transcriptional regulator
JIO02_RS09765	COG2814	Major facilitator Superfamily
JIO02_RS09790	COG1131	(ABC) transporter
JIO02_RS09800	COG4608	Belongs to the ABC transporter superfamily
JIO02_RS09805	COG0444	Belongs to the ABC transporter superfamily
JIO02_RS09815	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
JIO02_RS09820	COG0601	transmembrane transport
JIO02_RS09825	COG4166	transmembrane transport
JIO02_RS09840	COG1132	(ABC) transporter
JIO02_RS09845	COG1116	anion transmembrane transporter activity
JIO02_RS09860	COG5549	protein import
JIO02_RS09860	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
JIO02_RS09865	COG3620	sequence-specific DNA binding
JIO02_RS09910	COG3328	transposase activity
JIO02_RS09930	COG0791	NLP P60 protein
JIO02_RS09930	COG3103	Sh3 type 3 domain protein
JIO02_RS09930	COG1388	LysM domain
JIO02_RS09990	COG1674	ftsk spoiiie
JIO02_RS10020	COG2946	Replication initiation factor
JIO02_RS10060	COG0433	COG0433 Predicted ATPase
JIO02_RS10070	COG0741	lytic transglycosylase activity
JIO02_RS10070	COG0791	NLP P60 protein
JIO02_RS10085	COG2826	transposase and inactivated derivatives, IS30 family
JIO02_RS10105	COG1511	domain protein
JIO02_RS10170	COG0277	FAD linked oxidase domain protein
JIO02_RS10185	COG0318	PFAM AMP-dependent synthetase and ligase
JIO02_RS10245	COG1573	uracil-dna glycosylase
JIO02_RS10250	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
JIO02_RS10255	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
JIO02_RS10260	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
JIO02_RS10265	COG1215	transferase activity, transferring glycosyl groups
JIO02_RS10265	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
JIO02_RS10370	COG0519	Catalyzes the synthesis of GMP from XMP
JIO02_RS10390	COG4690	dipeptidase activity
JIO02_RS10395	COG1607	acyl-coa hydrolase
JIO02_RS10400	COG3973	AAA domain
JIO02_RS10410	COG0569	domain protein
JIO02_RS10410	COG0475	glutathione-regulated potassium exporter activity
JIO02_RS10415	COG2267	carboxylic ester hydrolase activity
JIO02_RS10425	COG1914	H( )-stimulated, divalent metal cation uptake system
JIO02_RS10435	COG0588	phosphoglycerate mutase activity
JIO02_RS10440	COG0235	Class ii aldolase
JIO02_RS10450	COG1136	(ABC) transporter
JIO02_RS10455	COG0531	amino acid
JIO02_RS10465	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
JIO02_RS10470	COG0726	polysaccharide deacetylase
JIO02_RS10485	COG0489	protein tyrosine kinase activity
JIO02_RS10505	COG1442	glycosyl transferase family 8
JIO02_RS10505	COG1216	Glycosyl transferase, family 2
JIO02_RS10515	COG3328	transposase activity
JIO02_RS10540	COG0463	Glycosyl transferase, family 2
JIO02_RS10545	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
JIO02_RS10560	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
JIO02_RS10570	COG0463	Glycosyl transferase, family 2
JIO02_RS10580	COG0765	amino acid transport
JIO02_RS10585	COG0765	amino acid transport
JIO02_RS10590	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JIO02_RS10610	COG0735	belongs to the Fur family
JIO02_RS10620	COG0194	GDP metabolic process
JIO02_RS10635	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
JIO02_RS10660	COG0058	SHG alpha-glucan phosphorylase activity
JIO02_RS10670	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
JIO02_RS10680	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
JIO02_RS10685	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
JIO02_RS10695	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
JIO02_RS10705	COG1393	Belongs to the ArsC family
JIO02_RS10715	COG4464	protein tyrosine phosphatase activity
JIO02_RS10720	COG1316	TRANSCRIPTIONal
JIO02_RS10760	COG0562	UDP-galactopyranose mutase
JIO02_RS10765	COG0489	protein tyrosine kinase activity
JIO02_RS10775	COG3328	transposase activity
JIO02_RS10785	COG4708	membrane
JIO02_RS10790	COG1028	Short-chain dehydrogenase reductase Sdr
JIO02_RS10810	COG4608	Belongs to the ABC transporter superfamily
JIO02_RS10815	COG0444	Belongs to the ABC transporter superfamily
JIO02_RS10820	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
JIO02_RS10825	COG0601	transmembrane transport
JIO02_RS10830	COG4166	transmembrane transport
JIO02_RS10840	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
JIO02_RS10845	COG1556	Lactate utilization protein
JIO02_RS10855	COG0247	lactate metabolic process
JIO02_RS10865	COG1447	Phosphotransferase system cellobiose-specific component IIA
JIO02_RS10885	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
JIO02_RS10920	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
JIO02_RS11020	COG0366	Alpha amylase catalytic
JIO02_RS11025	COG1609	Transcriptional regulator
JIO02_RS11040	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
JIO02_RS11055	COG0439	Biotin carboxylase
JIO02_RS11065	COG0511	ligase activity, forming carbon-carbon bonds
JIO02_RS11070	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
JIO02_RS11075	COG1028	Short-chain dehydrogenase reductase Sdr
JIO02_RS11085	COG2070	2-Nitropropane dioxygenase
JIO02_RS11095	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
JIO02_RS11105	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
JIO02_RS11115	COG1979	alcohol dehydrogenase
JIO02_RS11150	COG1846	Transcriptional regulator
JIO02_RS11155	COG0494	nUDIX hydrolase
JIO02_RS11160	COG0588	phosphoglycerate mutase activity
JIO02_RS11180	COG0628	permease
JIO02_RS11190	COG2246	polysaccharide biosynthetic process
JIO02_RS11195	COG0028	Belongs to the TPP enzyme family
JIO02_RS11240	COG0460	homoserine dehydrogenase
JIO02_RS11245	COG0527	aspartate kinase activity
JIO02_RS11250	COG2268	Band 7 protein
JIO02_RS11270	COG0436	Aminotransferase
JIO02_RS11285	COG0596	Alpha beta hydrolase
JIO02_RS11290	COG1309	transcriptional regulator
JIO02_RS11295	COG1511	domain protein
JIO02_RS11295	COG1511	domain protein
JIO02_RS11305	COG3711	transcriptional antiterminator
JIO02_RS11310	COG3711	transcriptional antiterminator
JIO02_RS11310	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
JIO02_RS11315	COG3775	system Galactitol-specific IIC component
JIO02_RS11320	COG3414	Phosphotransferase system galactitol-specific IIB component
JIO02_RS11330	COG0517	IMP dehydrogenase activity
JIO02_RS11330	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
JIO02_RS11335	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
JIO02_RS11340	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
JIO02_RS11345	COG0367	asparagine synthase
JIO02_RS11360	COG0142	geranyltranstransferase activity
JIO02_RS11370	COG4152	abc transporter atp-binding protein
JIO02_RS11385	COG1131	(ABC) transporter
JIO02_RS11395	COG1028	Short-chain dehydrogenase reductase Sdr
JIO02_RS11400	COG2723	6-phospho-beta-galactosidase activity
JIO02_RS11405	COG1263	PTS System
JIO02_RS11405	COG2190	(PTS) system
JIO02_RS11405	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JIO02_RS11410	COG3711	transcriptional antiterminator
JIO02_RS11415	COG1132	(ABC) transporter
JIO02_RS11420	COG1132	(ABC) transporter
JIO02_RS11435	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
JIO02_RS11440	COG4988	ABC transporter
JIO02_RS11445	COG1294	oxidase, subunit
JIO02_RS11450	COG1271	oxidase subunit
JIO02_RS11480	COG0697	spore germination
JIO02_RS11485	COG0519	Catalyzes the synthesis of GMP from XMP
JIO02_RS11500	COG2365	Tyrosine phosphatase family
JIO02_RS11505	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
JIO02_RS11515	COG1268	BioY protein
JIO02_RS11535	COG0505	Belongs to the CarA family
JIO02_RS11545	COG1253	flavin adenine dinucleotide binding
JIO02_RS11560	COG2814	Major facilitator Superfamily
JIO02_RS11585	COG0531	amino acid
JIO02_RS11605	COG1266	CAAX protease self-immunity
JIO02_RS11610	COG1316	TRANSCRIPTIONal
JIO02_RS11620	COG1131	(ABC) transporter
JIO02_RS11625	COG1725	Transcriptional regulator
JIO02_RS11630	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
JIO02_RS11635	COG0488	(ABC) transporter
JIO02_RS11640	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
JIO02_RS11655	COG1214	PFAM Peptidase M22, glycoprotease
JIO02_RS11690	COG0470	DNA polymerase III
JIO02_RS11695	COG3870	Protein conserved in bacteria
JIO02_RS11720	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
JIO02_RS11730	COG0590	tRNA wobble adenosine to inosine editing
JIO02_RS11740	COG2813	Specifically methylates the guanine in position
JIO02_RS11745	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
JIO02_RS11745	COG0392	lysyltransferase activity
JIO02_RS11770	COG1609	Transcriptional regulator
JIO02_RS11810	COG0477	Major facilitator Superfamily
JIO02_RS11825	COG0438	transferase activity, transferring glycosyl groups
JIO02_RS11830	COG0438	transferase activity, transferring glycosyl groups
JIO02_RS11835	COG1012	belongs to the aldehyde dehydrogenase family
JIO02_RS11855	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
JIO02_RS11865	COG2096	Adenosyltransferase
JIO02_RS11895	COG0250	Participates in transcription elongation, termination and antitermination
JIO02_RS11930	COG4939	FMN-binding domain protein
JIO02_RS11975	COG1131	(ABC) transporter
JIO02_RS12000	COG3688	RNA-binding protein containing a PIN domain
JIO02_RS12005	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
JIO02_RS12010	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
JIO02_RS12020	COG0277	FAD linked oxidase domain protein
JIO02_RS12035	COG4377	Putative membrane peptidase family (DUF2324)
JIO02_RS12045	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
JIO02_RS12055	COG3328	transposase activity
JIO02_RS12075	COG1131	(ABC) transporter
JIO02_RS12085	COG4956	integral membrane protein (PIN domain superfamily)
JIO02_RS12090	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
JIO02_RS12095	COG0756	dUTP diphosphatase activity
JIO02_RS12100	COG2388	GCN5-related N-acetyl-transferase
JIO02_RS12125	COG1131	(ABC) transporter
JIO02_RS12135	COG0574	Belongs to the PEP-utilizing enzyme family
JIO02_RS12135	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
JIO02_RS12140	COG0517	IMP dehydrogenase activity
JIO02_RS12145	COG0588	phosphoglycerate mutase activity
JIO02_RS12160	COG1304	FMN binding
JIO02_RS12170	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
JIO02_RS12235	COG3328	transposase activity
JIO02_RS12245	COG1136	(ABC) transporter
JIO02_RS12245	COG0577	efflux transmembrane transporter activity
JIO02_RS12250	COG1136	(ABC) transporter
JIO02_RS12300	COG1695	Transcriptional regulator
JIO02_RS12320	COG0667	Aldo Keto reductase
JIO02_RS12340	COG2274	protein secretion by the type I secretion system
JIO02_RS12355	COG3279	Response regulator of the LytR AlgR family
JIO02_RS12415	COG4989	oxidoreductase activity
JIO02_RS12420	COG4221	oxidoreductase activity
JIO02_RS12425	COG1902	pentaerythritol trinitrate reductase activity
JIO02_RS12435	COG0114	fumarate hydratase activity
JIO02_RS12450	COG1914	H( )-stimulated, divalent metal cation uptake system
JIO02_RS12455	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
JIO02_RS12465	COG2814	Major facilitator Superfamily
JIO02_RS12495	COG1108	ABC-type Mn2 Zn2 transport systems permease components
JIO02_RS12500	COG1121	(ABC) transporter
JIO02_RS12530	COG0803	Belongs to the bacterial solute-binding protein 9 family
JIO02_RS12540	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
JIO02_RS12575	COG1116	anion transmembrane transporter activity
JIO02_RS12580	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
JIO02_RS12610	COG1132	(ABC) transporter
JIO02_RS12640	COG1136	(ABC) transporter
JIO02_RS12650	COG0789	Transcriptional regulator
JIO02_RS12720	COG0200	Binds to the 23S rRNA
JIO02_RS12830	COG0450	alkyl hydroperoxide reductase
JIO02_RS12880	COG0542	response to heat
JIO02_RS12885	COG4463	regulation of RNA biosynthetic process
JIO02_RS12955	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
JIO02_RS12960	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
JIO02_RS12975	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
JIO02_RS12980	COG0037	tRNA processing
JIO02_RS12985	COG1098	S1 RNA binding domain
JIO02_RS12995	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
JIO02_RS13000	COG2244	polysaccharide biosynthetic process
JIO02_RS13005	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
JIO02_RS13015	COG0039	L-malate dehydrogenase activity
JIO02_RS13030	COG1511	domain protein
JIO02_RS13030	COG1511	domain protein
JIO02_RS13045	COG1376	ErfK ybiS ycfS ynhG family protein
JIO02_RS13050	COG0493	'glutamate synthase
JIO02_RS13055	COG0070	glutamate synthase
JIO02_RS13055	COG0069	glutamate synthase activity
JIO02_RS13055	COG0067	glutamate synthase
JIO02_RS13060	COG4708	membrane
JIO02_RS13065	COG2337	Toxic component of a toxin-antitoxin (TA) module
JIO02_RS13090	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
JIO02_RS13120	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
JIO02_RS13135	COG0504	CTP synthase activity
JIO02_RS13140	COG1252	NADH dehydrogenase
JIO02_RS13145	COG3328	transposase activity
JIO02_RS13175	COG0095	Lipoate-protein ligase
JIO02_RS13180	COG1078	dGTPase activity
JIO02_RS13210	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
JIO02_RS13215	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
JIO02_RS13225	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
JIO02_RS13230	COG4619	ABC transporter
JIO02_RS13235	COG0390	transport system, permease component
JIO02_RS13245	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
JIO02_RS13250	COG4466	Protein conserved in bacteria
JIO02_RS13255	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
JIO02_RS13260	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
JIO02_RS13265	COG0084	hydrolase, TatD family'
JIO02_RS13275	COG3684	Belongs to the aldolase LacD family
JIO02_RS13285	COG3279	Response regulator of the LytR AlgR family
JIO02_RS13290	COG3290	protein histidine kinase activity
JIO02_RS13295	COG1132	(ABC) transporter
JIO02_RS13300	COG1132	(ABC) transporter
JIO02_RS13315	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
JIO02_RS13315	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
JIO02_RS13325	COG1801	Protein of unknown function DUF72
JIO02_RS13345	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
JIO02_RS13355	COG1881	PFAM PEBP family protein
JIO02_RS13365	COG4086	secreted protein
JIO02_RS13370	COG0248	Ppx GppA phosphatase
JIO02_RS13375	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
JIO02_RS13385	COG4989	oxidoreductase activity
JIO02_RS13390	COG2226	methyltransferase
JIO02_RS13400	COG0534	Mate efflux family protein
JIO02_RS13405	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
JIO02_RS13410	COG1704	LemA family
JIO02_RS13420	COG3328	transposase activity
JIO02_RS13430	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
JIO02_RS13440	COG1174	glycine betaine transport
JIO02_RS13445	COG3973	AAA domain
JIO02_RS13450	COG0583	DNA-binding transcription factor activity
JIO02_RS13475	COG0640	Transcriptional regulator
JIO02_RS13495	COG1418	mRNA catabolic process
JIO02_RS13505	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
JIO02_RS13510	COG0667	Aldo Keto reductase
JIO02_RS13535	COG0588	phosphoglycerate mutase activity
JIO02_RS13540	COG0561	phosphatase activity
JIO02_RS13555	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
JIO02_RS13570	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
JIO02_RS13575	COG1811	Na channel or pump
JIO02_RS13590	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JIO02_RS13590	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JIO02_RS13590	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
JIO02_RS13595	COG1105	Belongs to the carbohydrate kinase PfkB family
JIO02_RS13605	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
JIO02_RS13615	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
JIO02_RS13620	COG0163	prenyltransferase activity
JIO02_RS13645	COG0477	Major facilitator Superfamily
JIO02_RS13660	COG3775	system Galactitol-specific IIC component
JIO02_RS13675	COG1349	DNA-binding transcription factor activity
JIO02_RS13685	COG0235	Class ii aldolase
JIO02_RS13690	COG4806	L-rhamnose isomerase
JIO02_RS13695	COG3254	rhamnose metabolic process
JIO02_RS13700	COG1070	Carbohydrate kinase
JIO02_RS13705	COG2814	Major facilitator Superfamily
JIO02_RS13725	COG3328	transposase activity
JIO02_RS13735	COG0366	Alpha amylase catalytic
JIO02_RS13765	COG3716	PTS system mannose fructose sorbose family IID component
JIO02_RS13770	COG3715	PTS system
JIO02_RS13780	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
JIO02_RS13790	COG1414	Transcriptional regulator
JIO02_RS13800	COG1028	Short-chain dehydrogenase reductase Sdr
JIO02_RS13825	COG5492	domain, Protein
JIO02_RS13830	COG3345	alpha-galactosidase
JIO02_RS13835	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
JIO02_RS13835	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JIO02_RS13840	COG3716	PTS system mannose fructose sorbose family IID component
JIO02_RS13845	COG3715	PTS system
JIO02_RS13855	COG1609	Transcriptional regulator
JIO02_RS13865	COG1263	PTS System
JIO02_RS13865	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JIO02_RS13870	COG1132	(ABC) transporter
JIO02_RS13885	COG2190	(PTS) system
JIO02_RS13885	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JIO02_RS13885	COG1263	PTS System
JIO02_RS13905	COG3964	amidohydrolase
JIO02_RS13950	COG3732	PTS system glucitol sorbitol-specific
JIO02_RS13955	COG3730	PTS system glucitol sorbitol-specific
JIO02_RS13965	COG3711	transcriptional antiterminator
JIO02_RS13965	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
JIO02_RS13990	COG0561	phosphatase activity
JIO02_RS13995	COG3623	hexulose-6-phosphate isomerase
JIO02_RS14005	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
JIO02_RS14020	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
JIO02_RS14045	COG1446	asparaginase
JIO02_RS14055	COG2188	Transcriptional regulator
JIO02_RS14075	COG1051	belongs to the nudix hydrolase family
JIO02_RS14100	COG1335	isochorismatase
JIO02_RS14105	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
JIO02_RS14110	COG0584	glycerophosphoryl diester phosphodiesterase
JIO02_RS14115	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
JIO02_RS14125	COG0395	ABC-type sugar transport system, permease component
JIO02_RS14135	COG3842	ATPase activity
JIO02_RS14150	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
JIO02_RS14160	COG1737	Transcriptional regulator
JIO02_RS14165	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JIO02_RS14170	COG3716	PTS system mannose fructose sorbose family IID component
JIO02_RS14185	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
JIO02_RS14190	COG0656	L-ascorbic acid biosynthetic process
JIO02_RS14195	COG0789	Transcriptional regulator
JIO02_RS14205	COG2076	Multidrug Resistance protein
JIO02_RS14220	COG1132	(ABC) transporter
JIO02_RS14250	COG2365	Tyrosine phosphatase family
JIO02_RS14290	COG4166	transmembrane transport
JIO02_RS14305	COG3328	transposase activity
JIO02_RS14310	COG2211	Major facilitator Superfamily
JIO02_RS14320	COG2217	Heavy metal translocating P-type atpase
JIO02_RS14325	COG0071	Belongs to the small heat shock protein (HSP20) family
JIO02_RS14335	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
JIO02_RS14340	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
JIO02_RS14355	COG5002	protein histidine kinase activity
JIO02_RS14360	COG0745	RESPONSE REGULATOR receiver
JIO02_RS14370	COG0765	amino acid transport
JIO02_RS14395	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
JIO02_RS14400	COG2188	Transcriptional regulator
JIO02_RS14405	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
JIO02_RS14410	COG1447	Phosphotransferase system cellobiose-specific component IIA
JIO02_RS14430	COG1335	isochorismatase
JIO02_RS14435	COG2814	Major facilitator Superfamily
JIO02_RS14440	COG2807	transmembrane transport
JIO02_RS14445	COG0667	Aldo Keto reductase
JIO02_RS14455	COG3716	PTS system mannose fructose sorbose family IID component
JIO02_RS14460	COG3715	PTS system
JIO02_RS14500	COG3409	Peptidoglycan-binding domain 1 protein
JIO02_RS14505	COG0765	amino acid transport
JIO02_RS14510	COG1126	abc transporter atp-binding protein
JIO02_RS14555	COG3001	Fructosamine kinase
JIO02_RS14560	COG1126	abc transporter atp-binding protein
JIO02_RS14565	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JIO02_RS14570	COG0765	amino acid transport
JIO02_RS14585	COG0714	Associated with various cellular activities
JIO02_RS14595	COG1305	Transglutaminase-like
JIO02_RS14600	COG0438	transferase activity, transferring glycosyl groups
JIO02_RS14625	COG3493	citrate carrier protein
JIO02_RS14630	COG3290	protein histidine kinase activity
JIO02_RS14635	COG4565	transcriptional regulatory protein
JIO02_RS14645	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
JIO02_RS14715	COG3328	transposase activity
JIO02_RS14745	COG4695	Portal protein
JIO02_RS14780	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
JIO02_RS14800	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
JIO02_RS14805	COG3711	transcriptional antiterminator
JIO02_RS14810	COG2213	PTS system mannitol-specific
JIO02_RS14820	COG0561	phosphatase activity
JIO02_RS14850	COG0577	efflux transmembrane transporter activity
JIO02_RS14850	COG1136	(ABC) transporter
JIO02_RS14860	COG0604	alcohol dehydrogenase
JIO02_RS14890	COG0436	Aminotransferase
JIO02_RS14895	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
JIO02_RS14915	COG0371	Dehydrogenase
JIO02_RS14930	COG1473	amidohydrolase
JIO02_RS14955	COG1132	(ABC) transporter
JIO02_RS14975	COG0706	membrane insertase activity
JIO02_RS15005	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
JIO02_RS15025	COG3711	transcriptional antiterminator
JIO02_RS15030	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
JIO02_RS15030	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
JIO02_RS15040	COG1447	Phosphotransferase system cellobiose-specific component IIA
JIO02_RS15055	COG2261	transglycosylase associated protein
JIO02_RS15090	COG2261	transglycosylase associated protein
JIO02_RS15110	COG1045	serine acetyltransferase
JIO02_RS15115	COG0626	cystathionine gamma-synthase activity
JIO02_RS15120	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
JIO02_RS15130	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
JIO02_RS15145	COG3328	transposase activity
JIO02_RS15170	COG2801	Transposase and inactivated derivatives
JIO02_RS15180	COG3328	transposase activity
JIO02_RS15200	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
JIO02_RS15210	COG4975	Glucose uptake
JIO02_RS15225	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JIO02_RS15225	COG2190	(PTS) system
JIO02_RS15225	COG1263	PTS System
JIO02_RS15230	COG0366	Alpha amylase catalytic
JIO02_RS15235	COG2188	Transcriptional regulator
JIO02_RS15255	COG1192	Involved in chromosome partitioning
JIO02_RS15360	COG2826	transposase and inactivated derivatives, IS30 family
JIO02_RS15385	COG3328	transposase activity
JIO02_RS15395	COG3328	transposase activity