locus-tag	class	description
CEW82_RS00050	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
CEW82_RS00060	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
CEW82_RS00070	COG1620	l-lactate permease
CEW82_RS00085	COG1113	amino acid transport
CEW82_RS00145	COG1307	EDD domain protein, DegV family
CEW82_RS00155	COG1293	RNA-binding protein homologous to eukaryotic snRNP
CEW82_RS00165	COG1131	(ABC) transporter
CEW82_RS00185	COG5646	InterPro IPR014922
CEW82_RS00200	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
CEW82_RS00205	COG0505	Belongs to the CarA family
CEW82_RS00210	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
CEW82_RS00215	COG0564	pseudouridine synthase activity
CEW82_RS00220	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
CEW82_RS00225	COG2759	Belongs to the formate--tetrahydrofolate ligase family
CEW82_RS00240	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CEW82_RS00275	COG1120	ATPase activity
CEW82_RS00295	COG1216	Glycosyl transferase, family 2
CEW82_RS00305	COG1073	alpha beta
CEW82_RS00320	COG0116	Belongs to the methyltransferase superfamily
CEW82_RS00330	COG3599	regulation of cell shape
CEW82_RS00335	COG4474	Belongs to the UPF0398 family
CEW82_RS00340	COG3331	DNA recombination
CEW82_RS00345	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CEW82_RS00350	COG3842	ATPase activity
CEW82_RS00355	COG1840	ABC-type Fe3 transport system, periplasmic component
CEW82_RS00365	COG0589	response to stress
CEW82_RS00370	COG1464	Belongs to the NlpA lipoprotein family
CEW82_RS00375	COG2011	ABC-type metal ion transport system permease component
CEW82_RS00380	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CEW82_RS00405	COG1199	ATP-dependent helicase activity
CEW82_RS00405	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CEW82_RS00430	COG1304	FMN binding
CEW82_RS00435	COG2271	Major facilitator Superfamily
CEW82_RS00440	COG0066	3-isopropylmalate dehydratase activity
CEW82_RS00445	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
CEW82_RS00455	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CEW82_RS00460	COG2017	converts alpha-aldose to the beta-anomer
CEW82_RS00500	COG3835	regulator
CEW82_RS00510	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
CEW82_RS00510	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CEW82_RS00515	COG0561	phosphatase activity
CEW82_RS00520	COG0531	amino acid
CEW82_RS00580	COG0019	diaminopimelate decarboxylase activity
CEW82_RS00585	COG1942	4-Oxalocrotonate Tautomerase
CEW82_RS00620	COG1597	lipid kinase activity
CEW82_RS00625	COG3152	Membrane
CEW82_RS00635	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
CEW82_RS00695	COG1162	GTPase activity
CEW82_RS00700	COG1607	acyl-coa hydrolase
CEW82_RS00705	COG0583	DNA-binding transcription factor activity
CEW82_RS00710	COG1811	Na channel or pump
CEW82_RS00720	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
CEW82_RS00735	COG0439	Biotin carboxylase
CEW82_RS00745	COG0511	ligase activity, forming carbon-carbon bonds
CEW82_RS00750	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CEW82_RS00755	COG1028	Short-chain dehydrogenase reductase Sdr
CEW82_RS00765	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CEW82_RS00770	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CEW82_RS00775	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CEW82_RS00790	COG1063	alcohol dehydrogenase
CEW82_RS00795	COG0789	Transcriptional regulator
CEW82_RS00805	COG1473	amidohydrolase
CEW82_RS00815	COG0159	tryptophan synthase activity
CEW82_RS00820	COG0133	tryptophan synthase activity
CEW82_RS00825	COG0135	phosphoribosylanthranilate isomerase activity
CEW82_RS00830	COG0134	indole-3-glycerol-phosphate synthase activity
CEW82_RS00835	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CEW82_RS00840	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CEW82_RS00840	COG0512	Glutamine amidotransferase of anthranilate synthase
CEW82_RS00855	COG1131	(ABC) transporter
CEW82_RS00870	COG0477	Major facilitator Superfamily
CEW82_RS00875	COG0335	large ribosomal subunit rRNA binding
CEW82_RS00880	COG0336	Belongs to the RNA methyltransferase TrmD family
CEW82_RS00885	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
CEW82_RS00890	COG1837	Belongs to the UPF0109 family
CEW82_RS00895	COG0228	four-way junction DNA binding
CEW82_RS00900	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CEW82_RS00905	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
CEW82_RS00910	COG0552	protein localization to endoplasmic reticulum
CEW82_RS00915	COG1196	nuclear chromosome segregation
CEW82_RS00920	COG0571	ribonuclease III activity
CEW82_RS00925	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CEW82_RS00930	COG0416	fatty acid biosynthetic process
CEW82_RS00935	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CEW82_RS00940	COG1461	Dihydroxyacetone kinase
CEW82_RS00945	COG1302	Protein conserved in bacteria
CEW82_RS00950	COG0227	Belongs to the bacterial ribosomal protein bL28 family
CEW82_RS00955	COG1564	THIamine pyrophosphokinase
CEW82_RS00960	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CEW82_RS00965	COG1162	GTPase activity
CEW82_RS00970	COG0515	serine threonine protein kinase
CEW82_RS00970	COG2815	serine threonine protein kinase
CEW82_RS00975	COG0631	protein serine/threonine phosphatase activity
CEW82_RS00980	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CEW82_RS00980	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CEW82_RS00990	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CEW82_RS00995	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CEW82_RS01000	COG1758	RNA polymerase activity
CEW82_RS01005	COG0194	GDP metabolic process
CEW82_RS01035	COG0497	DNA recombination
CEW82_RS01040	COG1438	arginine binding
CEW82_RS01045	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
CEW82_RS01050	COG0142	geranyltranstransferase activity
CEW82_RS01055	COG1722	exodeoxyribonuclease VII activity
CEW82_RS01060	COG1570	exodeoxyribonuclease VII activity
CEW82_RS01065	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
CEW82_RS01070	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CEW82_RS01075	COG1302	Protein conserved in bacteria
CEW82_RS01080	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
CEW82_RS01085	COG0006	proline dipeptidase activity
CEW82_RS01090	COG0211	Belongs to the bacterial ribosomal protein bL27 family
CEW82_RS01100	COG0261	This protein binds to 23S rRNA in the presence of protein L20
CEW82_RS01155	COG0789	Transcriptional regulator
CEW82_RS01160	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
CEW82_RS01165	COG0584	glycerophosphoryl diester phosphodiesterase
CEW82_RS01185	COG1940	carbohydrate kinase activity
CEW82_RS01200	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
CEW82_RS01205	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CEW82_RS01210	COG0768	penicillin binding
CEW82_RS01220	COG4841	protein insertion into membrane
CEW82_RS01235	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CEW82_RS01240	COG0572	uridine kinase
CEW82_RS01245	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CEW82_RS01250	COG0072	phenylalanine-tRNA ligase activity
CEW82_RS01250	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CEW82_RS01255	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
CEW82_RS01260	COG1733	regulation of RNA biosynthetic process
CEW82_RS01270	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CEW82_RS01275	COG1254	Belongs to the acylphosphatase family
CEW82_RS01280	COG0706	membrane insertase activity
CEW82_RS01290	COG0420	3'-5' exonuclease activity
CEW82_RS01295	COG0419	ATPase involved in DNA repair
CEW82_RS01310	COG5002	protein histidine kinase activity
CEW82_RS01315	COG0745	RESPONSE REGULATOR receiver
CEW82_RS01320	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CEW82_RS01325	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
CEW82_RS01335	COG0333	Belongs to the bacterial ribosomal protein bL32 family
CEW82_RS01345	COG1323	Belongs to the UPF0348 family
CEW82_RS01350	COG2226	methyltransferase
CEW82_RS01355	COG0799	negative regulation of ribosome biogenesis
CEW82_RS01360	COG1713	HD superfamily hydrolase involved in NAD metabolism
CEW82_RS01365	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
CEW82_RS01370	COG1534	Rna-binding protein
CEW82_RS01375	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
CEW82_RS01405	COG1857	crispr-associated protein
CEW82_RS01425	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CEW82_RS01430	COG1518	maintenance of DNA repeat elements
CEW82_RS01445	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
CEW82_RS01450	COG0291	Belongs to the bacterial ribosomal protein bL35 family
CEW82_RS01455	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
CEW82_RS01460	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
CEW82_RS01465	COG1484	DNA-dependent DNA replication
CEW82_RS01470	COG3611	Membrane attachment protein
CEW82_RS01475	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
CEW82_RS01480	COG0237	dephospho-CoA kinase activity
CEW82_RS01485	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
CEW82_RS01490	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CEW82_RS01490	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CEW82_RS01500	COG3655	Transcriptional regulator
CEW82_RS01520	COG2181	nitrate reductase activity
CEW82_RS01530	COG1140	nitrate reductase beta subunit
CEW82_RS01535	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
CEW82_RS01555	COG1763	Mo-molybdopterin cofactor biosynthetic process
CEW82_RS01560	COG0315	cyclic pyranopterin monophosphate synthase activity
CEW82_RS01565	COG0746	molybdenum cofactor guanylyltransferase activity
CEW82_RS01585	COG2197	response regulator
CEW82_RS01610	COG2151	metal-sulfur cluster biosynthetic enzyme
CEW82_RS01615	COG2223	nitrite transmembrane transporter activity
CEW82_RS01620	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
CEW82_RS01640	COG0716	FMN binding
CEW82_RS01645	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CEW82_RS01650	COG1120	ATPase activity
CEW82_RS01665	COG0719	Fe-S assembly protein
CEW82_RS01675	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CEW82_RS01680	COG0719	Fe-S assembly protein
CEW82_RS01705	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CEW82_RS01710	COG1674	ftsk spoiiie
CEW82_RS01715	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CEW82_RS01750	COG0220	tRNA (guanine-N7-)-methyltransferase activity
CEW82_RS01755	COG0510	thiamine kinase activity
CEW82_RS01765	COG1131	(ABC) transporter
CEW82_RS01770	COG0537	adenosine 5'-monophosphoramidase activity
CEW82_RS01780	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CEW82_RS01820	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CEW82_RS01855	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
CEW82_RS01860	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CEW82_RS01860	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CEW82_RS01870	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CEW82_RS01870	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CEW82_RS01885	COG0463	Glycosyl transferase, family 2
CEW82_RS01895	COG1053	succinate dehydrogenase
CEW82_RS01895	COG3976	FMN-binding domain protein
CEW82_RS01895	COG0431	NADPH-dependent FMN reductase
CEW82_RS01900	COG3976	FMN-binding domain protein
CEW82_RS01900	COG1053	succinate dehydrogenase
CEW82_RS01900	COG0431	NADPH-dependent FMN reductase
CEW82_RS01905	COG0583	DNA-binding transcription factor activity
CEW82_RS01925	COG3481	metal-dependent phosphohydrolase, HD sub domain
CEW82_RS01930	COG4717	serine-type aminopeptidase activity
CEW82_RS01935	COG0420	3'-5' exonuclease activity
CEW82_RS01940	COG3679	Belongs to the UPF0342 family
CEW82_RS01945	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CEW82_RS01955	COG1438	arginine binding
CEW82_RS01960	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CEW82_RS01970	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CEW82_RS01975	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CEW82_RS01980	COG1376	ErfK ybiS ycfS ynhG family protein
CEW82_RS01995	COG0577	efflux transmembrane transporter activity
CEW82_RS01995	COG1136	(ABC) transporter
CEW82_RS02005	COG0018	arginyl-trna synthetase
CEW82_RS02010	COG2153	protein acetylation
CEW82_RS02030	COG0534	Mate efflux family protein
CEW82_RS02045	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
CEW82_RS02050	COG0529	Catalyzes the synthesis of activated sulfate
CEW82_RS02055	COG2046	Belongs to the sulfate adenylyltransferase family
CEW82_RS02070	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
CEW82_RS02125	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CEW82_RS02140	COG1846	Transcriptional regulator
CEW82_RS02165	COG3279	Response regulator of the LytR AlgR family
CEW82_RS02185	COG0561	phosphatase activity
CEW82_RS02205	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CEW82_RS02215	COG1511	domain protein
CEW82_RS02220	COG1970	mechanosensitive ion channel activity
CEW82_RS02225	COG1428	Deoxynucleoside kinase
CEW82_RS02230	COG0584	glycerophosphoryl diester phosphodiesterase
CEW82_RS02245	COG1175	transmembrane transport
CEW82_RS02250	COG3842	ATPase activity
CEW82_RS02260	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CEW82_RS02265	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
CEW82_RS02270	COG1187	pseudouridine synthase activity
CEW82_RS02275	COG2244	polysaccharide biosynthetic process
CEW82_RS02285	COG0495	leucyl-tRNA aminoacylation
CEW82_RS02295	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
CEW82_RS02325	COG2814	Major facilitator Superfamily
CEW82_RS02330	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
CEW82_RS02340	COG0438	transferase activity, transferring glycosyl groups
CEW82_RS02345	COG2040	homocysteine
CEW82_RS02350	COG0833	amino acid
CEW82_RS02355	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
CEW82_RS02400	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CEW82_RS02495	COG1368	sulfuric ester hydrolase activity
CEW82_RS02500	COG4703	Protein of unknown function (DUF1797)
CEW82_RS02505	COG0436	Aminotransferase
CEW82_RS02510	COG1686	Belongs to the peptidase S11 family
CEW82_RS02520	COG0438	transferase activity, transferring glycosyl groups
CEW82_RS02525	COG0438	transferase activity, transferring glycosyl groups
CEW82_RS02550	COG0542	response to heat
CEW82_RS02565	COG0582	viral genome integration into host DNA
CEW82_RS02575	COG4608	Belongs to the ABC transporter superfamily
CEW82_RS02580	COG0444	Belongs to the ABC transporter superfamily
CEW82_RS02585	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CEW82_RS02590	COG0601	transmembrane transport
CEW82_RS02595	COG4166	transmembrane transport
CEW82_RS02610	COG0583	DNA-binding transcription factor activity
CEW82_RS02630	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
CEW82_RS02640	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
CEW82_RS02645	COG1070	Carbohydrate kinase
CEW82_RS02650	COG2610	gluconate transmembrane transporter activity
CEW82_RS02655	COG0628	permease
CEW82_RS02665	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CEW82_RS02685	COG3557	Belongs to the UPF0374 family
CEW82_RS02690	COG2137	regulation of response to DNA damage stimulus
CEW82_RS02735	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CEW82_RS02775	COG0562	UDP-galactopyranose mutase
CEW82_RS02785	COG1215	transferase activity, transferring glycosyl groups
CEW82_RS02830	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
CEW82_RS02835	COG1091	dTDP-4-dehydrorhamnose reductase activity
CEW82_RS02840	COG1088	dTDP-glucose 4,6-dehydratase activity
CEW82_RS02850	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
CEW82_RS02855	COG2244	polysaccharide biosynthetic process
CEW82_RS02870	COG1215	transferase activity, transferring glycosyl groups
CEW82_RS02875	COG3475	LICD family
CEW82_RS02880	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CEW82_RS02890	COG4464	protein tyrosine phosphatase activity
CEW82_RS02895	COG0489	protein tyrosine kinase activity
CEW82_RS02915	COG1091	dTDP-4-dehydrorhamnose reductase activity
CEW82_RS02920	COG1088	dTDP-glucose 4,6-dehydratase activity
CEW82_RS02930	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
CEW82_RS02960	COG0110	maltose O-acetyltransferase activity
CEW82_RS02965	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
CEW82_RS02965	COG1215	transferase activity, transferring glycosyl groups
CEW82_RS02985	COG1395	domain, Protein
CEW82_RS02995	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
CEW82_RS03005	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
CEW82_RS03015	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CEW82_RS03040	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CEW82_RS03085	COG0513	Belongs to the DEAD box helicase family
CEW82_RS03090	COG0673	inositol 2-dehydrogenase activity
CEW82_RS03100	COG1278	Cold shock
CEW82_RS03115	COG1737	Transcriptional regulator
CEW82_RS03125	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CEW82_RS03125	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CEW82_RS03165	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CEW82_RS03170	COG1597	lipid kinase activity
CEW82_RS03175	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CEW82_RS03180	COG0154	amidase activity
CEW82_RS03185	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CEW82_RS03190	COG4851	CamS sex pheromone cAM373 precursor
CEW82_RS03195	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CEW82_RS03210	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
CEW82_RS03215	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
CEW82_RS03220	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CEW82_RS03225	COG1705	Flagellar rod assembly protein muramidase FlgJ
CEW82_RS03235	COG0142	geranyltranstransferase activity
CEW82_RS03245	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
CEW82_RS03250	COG4988	ABC transporter
CEW82_RS03255	COG1294	oxidase, subunit
CEW82_RS03260	COG1271	oxidase subunit
CEW82_RS03275	COG4684	Psort location CytoplasmicMembrane, score
CEW82_RS03280	COG0531	amino acid
CEW82_RS03295	COG0281	malic enzyme
CEW82_RS03310	COG0583	DNA-binding transcription factor activity
CEW82_RS03320	COG1053	succinate dehydrogenase
CEW82_RS03325	COG0114	fumarate hydratase activity
CEW82_RS03345	COG3052	prosthetic group binding
CEW82_RS03355	COG0281	malic enzyme
CEW82_RS03365	COG0471	metal ion transport
CEW82_RS03370	COG0039	L-malate dehydrogenase activity
CEW82_RS03395	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CEW82_RS03400	COG1121	(ABC) transporter
CEW82_RS03405	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
CEW82_RS03410	COG1917	Cupin 2, conserved barrel domain protein
CEW82_RS03410	COG4977	sequence-specific DNA binding
CEW82_RS03420	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
CEW82_RS03425	COG2151	metal-sulfur cluster biosynthetic enzyme
CEW82_RS03430	COG0471	metal ion transport
CEW82_RS03435	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
CEW82_RS03440	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
CEW82_RS03445	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CEW82_RS03450	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CEW82_RS03490	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
CEW82_RS03495	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
CEW82_RS03500	COG0101	tRNA pseudouridine synthase activity
CEW82_RS03510	COG1122	ATPase activity
CEW82_RS03515	COG1122	ATPase activity
CEW82_RS03525	COG4939	FMN-binding domain protein
CEW82_RS03550	COG0203	ribosomal protein L17
CEW82_RS03555	COG0202	RNA polymerase activity
CEW82_RS03560	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
CEW82_RS03565	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
CEW82_RS03570	COG0257	Belongs to the bacterial ribosomal protein bL36 family
CEW82_RS03575	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
CEW82_RS03580	COG0563	adenylate kinase activity
CEW82_RS03590	COG0200	Binds to the 23S rRNA
CEW82_RS03595	COG1841	ribosomal large subunit assembly
CEW82_RS03600	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
CEW82_RS03605	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
CEW82_RS03610	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
CEW82_RS03615	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
CEW82_RS03620	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
CEW82_RS03625	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
CEW82_RS03630	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
CEW82_RS03635	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
CEW82_RS03640	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
CEW82_RS03645	COG0255	Belongs to the universal ribosomal protein uL29 family
CEW82_RS03650	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
CEW82_RS03655	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
CEW82_RS03660	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
CEW82_RS03665	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
CEW82_RS03670	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
CEW82_RS03675	COG0089	rRNA binding
CEW82_RS03680	COG0088	Forms part of the polypeptide exit tunnel
CEW82_RS03690	COG0051	transcription antitermination factor activity, RNA binding
CEW82_RS03700	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CEW82_RS03705	COG0049	tRNA binding
CEW82_RS03710	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
CEW82_RS03715	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
CEW82_RS03720	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CEW82_RS03725	COG0085	RNA polymerase activity
CEW82_RS03735	COG0542	response to heat
CEW82_RS03740	COG4463	regulation of RNA biosynthetic process
CEW82_RS03780	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
CEW82_RS03785	COG1428	Deoxynucleoside kinase
CEW82_RS03795	COG0833	amino acid
CEW82_RS03800	COG0028	Belongs to the TPP enzyme family
CEW82_RS03805	COG1959	2 iron, 2 sulfur cluster binding
CEW82_RS03825	COG1316	TRANSCRIPTIONal
CEW82_RS03845	COG2966	Psort location CytoplasmicMembrane, score
CEW82_RS03850	COG1278	Cold shock
CEW82_RS03870	COG2814	Major facilitator Superfamily
CEW82_RS03910	COG0367	asparagine synthase
CEW82_RS03915	COG0527	aspartate kinase activity
CEW82_RS03970	COG0640	Transcriptional regulator
CEW82_RS03975	COG0564	pseudouridine synthase activity
CEW82_RS03980	COG0514	ATP-dependent DNA helicase (RecQ)
CEW82_RS04000	COG4690	dipeptidase activity
CEW82_RS04005	COG2502	aspartate--ammonia ligase
CEW82_RS04010	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
CEW82_RS04025	COG1053	succinate dehydrogenase
CEW82_RS04030	COG0583	DNA-binding transcription factor activity
CEW82_RS04075	COG1302	Protein conserved in bacteria
CEW82_RS04090	COG2261	transglycosylase associated protein
CEW82_RS04110	COG1266	CAAX protease self-immunity
CEW82_RS04135	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CEW82_RS04135	COG0519	Catalyzes the synthesis of GMP from XMP
CEW82_RS04140	COG1072	(Pantothenic acid kinase))
CEW82_RS04145	COG2723	6-phospho-beta-galactosidase activity
CEW82_RS04150	COG1263	PTS System
CEW82_RS04150	COG2190	(PTS) system
CEW82_RS04150	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CEW82_RS04155	COG1737	Transcriptional regulator
CEW82_RS04160	COG2070	2-Nitropropane dioxygenase
CEW82_RS04165	COG3973	AAA domain
CEW82_RS04170	COG0586	Pfam SNARE associated Golgi protein
CEW82_RS04175	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
CEW82_RS04180	COG0569	domain protein
CEW82_RS04180	COG0475	glutathione-regulated potassium exporter activity
CEW82_RS04185	COG0588	phosphoglycerate mutase activity
CEW82_RS04190	COG0406	alpha-ribazole phosphatase activity
CEW82_RS04200	COG2076	Multidrug Resistance protein
CEW82_RS04210	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CEW82_RS04235	COG0531	amino acid
CEW82_RS04240	COG0765	amino acid transport
CEW82_RS04245	COG0765	amino acid transport
CEW82_RS04250	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CEW82_RS04265	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CEW82_RS04270	COG0436	Aminotransferase
CEW82_RS04280	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CEW82_RS04295	COG0735	belongs to the Fur family
CEW82_RS04300	COG0194	GDP metabolic process
CEW82_RS04325	COG0531	amino acid
CEW82_RS04340	COG2936	dipeptidyl-peptidase activity
CEW82_RS04345	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
CEW82_RS04345	COG2755	lipolytic protein G-D-S-L family
CEW82_RS04355	COG2267	carboxylic ester hydrolase activity
CEW82_RS04360	COG0028	Belongs to the TPP enzyme family
CEW82_RS04365	COG0196	riboflavin kinase activity
CEW82_RS04370	COG0028	Belongs to the TPP enzyme family
CEW82_RS04375	COG2252	PERMEase
CEW82_RS04390	COG3475	LICD family
CEW82_RS04405	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
CEW82_RS04415	COG0477	Major facilitator Superfamily
CEW82_RS04430	COG1393	Belongs to the ArsC family
CEW82_RS04445	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CEW82_RS04455	COG0778	Nitroreductase
CEW82_RS04485	COG0561	phosphatase activity
CEW82_RS04490	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CEW82_RS04495	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CEW82_RS04520	COG0025	NhaP-type Na H and K H
CEW82_RS04525	COG0812	UDP-N-acetylmuramate dehydrogenase activity
CEW82_RS04540	COG0708	Exodeoxyribonuclease III
CEW82_RS04555	COG0802	atpase or kinase
CEW82_RS04560	COG0280	phosphate acetyltransferase
CEW82_RS04565	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
CEW82_RS04570	COG0561	phosphatase activity
CEW82_RS04585	COG1126	abc transporter atp-binding protein
CEW82_RS04590	COG0765	amino acid transport
CEW82_RS04600	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
CEW82_RS04605	COG0557	exoribonuclease II activity
CEW82_RS04615	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CEW82_RS04620	COG0038	chloride channel
CEW82_RS04630	COG0148	phosphopyruvate hydratase activity
CEW82_RS04635	COG0149	triose-phosphate isomerase activity
CEW82_RS04640	COG0126	phosphoglycerate kinase activity
CEW82_RS04650	COG2390	Transcriptional regulator
CEW82_RS04655	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
CEW82_RS04670	COG1028	Short-chain dehydrogenase reductase Sdr
CEW82_RS04675	COG0740	serine-type endopeptidase activity
CEW82_RS04680	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CEW82_RS04685	COG4166	transmembrane transport
CEW82_RS04690	COG1481	regulation of sporulation
CEW82_RS04700	COG1660	Displays ATPase and GTPase activities
CEW82_RS04710	COG0165	Argininosuccinate lyase
CEW82_RS04715	COG0137	argininosuccinate synthase activity
CEW82_RS04720	COG1854	S-ribosylhomocysteine lyase activity
CEW82_RS04725	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CEW82_RS04730	COG0556	nucleotide-excision repair
CEW82_RS04740	COG2814	Major facilitator Superfamily
CEW82_RS04750	COG0446	pyridine nucleotide-disulphide oxidoreductase
CEW82_RS04760	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CEW82_RS04770	COG2323	membrane
CEW82_RS04775	COG0492	ferredoxin-NADP+ reductase activity
CEW82_RS04790	COG1215	transferase activity, transferring glycosyl groups
CEW82_RS04810	COG0446	pyridine nucleotide-disulphide oxidoreductase
CEW82_RS04820	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CEW82_RS04825	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
CEW82_RS04830	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
CEW82_RS04835	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
CEW82_RS04840	COG1950	PFAM Membrane protein of
CEW82_RS04845	COG1983	PspC domain protein
CEW82_RS04850	COG0704	Plays a role in the regulation of phosphate uptake
CEW82_RS04855	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CEW82_RS04860	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CEW82_RS04865	COG0581	inorganic phosphate transmembrane transporter activity
CEW82_RS04870	COG0573	inorganic phosphate transmembrane transporter activity
CEW82_RS04880	COG5002	protein histidine kinase activity
CEW82_RS04885	COG0745	RESPONSE REGULATOR receiver
CEW82_RS04895	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
CEW82_RS04900	COG0653	protein targeting
CEW82_RS04910	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
CEW82_RS04915	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
CEW82_RS04920	COG1739	Uncharacterized protein family UPF0029
CEW82_RS04925	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
CEW82_RS04930	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CEW82_RS04935	COG0531	amino acid
CEW82_RS04940	COG0459	protein refolding
CEW82_RS04945	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
CEW82_RS04955	COG1266	CAAX protease self-immunity
CEW82_RS04960	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
CEW82_RS04965	COG0488	(ABC) transporter
CEW82_RS04970	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
CEW82_RS04975	COG0456	acetyltransferase
CEW82_RS04980	COG0456	acetyltransferase
CEW82_RS04985	COG1214	PFAM Peptidase M22, glycoprotease
CEW82_RS04995	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
CEW82_RS05005	COG3639	organic phosphonate transmembrane transporter activity
CEW82_RS05010	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CEW82_RS05015	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
CEW82_RS05025	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CEW82_RS05040	COG4467	Involved in initiation control of chromosome replication
CEW82_RS05045	COG0470	DNA polymerase III
CEW82_RS05050	COG3870	Protein conserved in bacteria
CEW82_RS05055	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
CEW82_RS05090	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
CEW82_RS05095	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
CEW82_RS05100	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CEW82_RS05110	COG0590	tRNA wobble adenosine to inosine editing
CEW82_RS05115	COG2813	Specifically methylates the guanine in position
CEW82_RS05120	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CEW82_RS05125	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CEW82_RS05135	COG1611	Belongs to the LOG family
CEW82_RS05145	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
CEW82_RS05145	COG0392	lysyltransferase activity
CEW82_RS05170	COG0222	ribosome binding
CEW82_RS05175	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
CEW82_RS05180	COG0081	regulation of translation
CEW82_RS05185	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
CEW82_RS05195	COG0250	Participates in transcription elongation, termination and antitermination
CEW82_RS05200	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CEW82_RS05205	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CEW82_RS05220	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CEW82_RS05225	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
CEW82_RS05230	COG0215	cysteine-tRNA ligase activity
CEW82_RS05240	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CEW82_RS05245	COG4956	integral membrane protein (PIN domain superfamily)
CEW82_RS05255	COG0756	dUTP diphosphatase activity
CEW82_RS05265	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
CEW82_RS05295	COG0588	phosphoglycerate mutase activity
CEW82_RS05300	COG0697	spore germination
CEW82_RS05310	COG1316	TRANSCRIPTIONal
CEW82_RS05320	COG0825	malonyl-CoA metabolic process
CEW82_RS05340	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CEW82_RS05345	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
CEW82_RS05345	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CEW82_RS05350	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CEW82_RS05350	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
CEW82_RS05355	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
CEW82_RS05355	COG3933	PFAM sigma-54 factor interaction domain-containing protein
CEW82_RS05365	COG3716	PTS system mannose fructose sorbose family IID component
CEW82_RS05370	COG3715	PTS system
CEW82_RS05580	COG3646	Phage regulatory protein
CEW82_RS05595	COG1396	sequence-specific DNA binding
CEW82_RS05645	COG0582	viral genome integration into host DNA
CEW82_RS05655	COG0083	homoserine kinase activity
CEW82_RS05660	COG0460	homoserine dehydrogenase
CEW82_RS05665	COG3091	SprT-like family
CEW82_RS05670	COG2183	response to ionizing radiation
CEW82_RS05685	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
CEW82_RS05690	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
CEW82_RS05700	COG2188	Transcriptional regulator
CEW82_RS05710	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CEW82_RS05755	COG3104	oligopeptide transport
CEW82_RS05800	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
CEW82_RS05805	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CEW82_RS05810	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
CEW82_RS05825	COG0037	tRNA processing
CEW82_RS05835	COG1098	S1 RNA binding domain
CEW82_RS05845	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
CEW82_RS05850	COG2244	polysaccharide biosynthetic process
CEW82_RS05855	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CEW82_RS05860	COG0193	aminoacyl-tRNA hydrolase activity
CEW82_RS05890	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
CEW82_RS05895	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CEW82_RS05900	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
CEW82_RS05905	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
CEW82_RS05910	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
CEW82_RS05915	COG0505	Belongs to the CarA family
CEW82_RS05920	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
CEW82_RS05940	COG3158	transport of potassium into the cell
CEW82_RS05945	COG2337	Toxic component of a toxin-antitoxin (TA) module
CEW82_RS05950	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CEW82_RS05955	COG0736	holo-[acyl-carrier-protein] synthase activity
CEW82_RS05970	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
CEW82_RS05980	COG0501	Belongs to the peptidase M48B family
CEW82_RS05985	COG1704	LemA family
CEW82_RS05990	COG3764	Sortase (surface protein transpeptidase)
CEW82_RS06005	COG0254	rRNA binding
CEW82_RS06010	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
CEW82_RS06015	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CEW82_RS06035	COG1760	l-serine dehydratase
CEW82_RS06040	COG1760	l-serine dehydratase
CEW82_RS06050	COG0814	amino acid
CEW82_RS06055	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
CEW82_RS06075	COG0655	NAD(P)H dehydrogenase (quinone) activity
CEW82_RS06085	COG0504	CTP synthase activity
CEW82_RS06090	COG3343	RNA polymerase activity
CEW82_RS06100	COG0095	Lipoate-protein ligase
CEW82_RS06105	COG1078	dGTPase activity
CEW82_RS06125	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CEW82_RS06135	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
CEW82_RS06140	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CEW82_RS06145	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CEW82_RS06145	COG1321	iron dependent repressor
CEW82_RS06150	COG1121	(ABC) transporter
CEW82_RS06155	COG1073	alpha beta
CEW82_RS06160	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
CEW82_RS06165	COG4466	Protein conserved in bacteria
CEW82_RS06170	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
CEW82_RS06175	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
CEW82_RS06180	COG0084	hydrolase, TatD family'
CEW82_RS06190	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CEW82_RS06190	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CEW82_RS06195	COG1801	Protein of unknown function DUF72
CEW82_RS06200	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
CEW82_RS06215	COG0248	Ppx GppA phosphatase
CEW82_RS06225	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CEW82_RS06240	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CEW82_RS06255	COG0444	Belongs to the ABC transporter superfamily
CEW82_RS06260	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CEW82_RS06265	COG0601	transmembrane transport
CEW82_RS06270	COG4166	transmembrane transport
CEW82_RS06280	COG0180	Tryptophanyl-tRNA synthetase
CEW82_RS06285	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CEW82_RS06290	COG3973	AAA domain
CEW82_RS06350	COG1136	(ABC) transporter
CEW82_RS06350	COG0577	efflux transmembrane transporter activity
CEW82_RS06355	COG3290	protein histidine kinase activity
CEW82_RS06415	COG1114	Component of the transport system for branched-chain amino acids
CEW82_RS06420	COG0561	phosphatase activity
CEW82_RS06430	COG0561	phosphatase activity
CEW82_RS06440	COG0110	maltose O-acetyltransferase activity
CEW82_RS06445	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
CEW82_RS06455	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CEW82_RS06470	COG1125	glycine betaine transport
CEW82_RS06490	COG0300	oxidoreductase activity
CEW82_RS06520	COG1881	PFAM PEBP family protein
CEW82_RS06525	COG3759	membrane
CEW82_RS06535	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
CEW82_RS06555	COG0004	ammonium transporteR
CEW82_RS06565	COG1134	teichoic acid transport
CEW82_RS06570	COG1682	transport, permease protein
CEW82_RS06585	COG0436	Aminotransferase
CEW82_RS06590	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CEW82_RS06595	COG2011	ABC-type metal ion transport system permease component
CEW82_RS06605	COG1464	Belongs to the NlpA lipoprotein family
CEW82_RS06620	COG1268	BioY protein
CEW82_RS06625	COG1132	(ABC) transporter
CEW82_RS06675	COG1012	belongs to the aldehyde dehydrogenase family
CEW82_RS06675	COG1454	alcohol dehydrogenase
CEW82_RS06685	COG1131	(ABC) transporter
CEW82_RS06690	COG1725	Transcriptional regulator
CEW82_RS06725	COG3842	ATPase activity
CEW82_RS06765	COG1252	NADH dehydrogenase
CEW82_RS06770	COG1846	Transcriptional regulator
CEW82_RS06780	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CEW82_RS06815	COG0741	lytic transglycosylase activity
CEW82_RS06825	COG1136	(ABC) transporter
CEW82_RS06830	COG0577	efflux transmembrane transporter activity
CEW82_RS06840	COG2818	Glycosylase
CEW82_RS06845	COG2409	Drug exporters of the RND superfamily
CEW82_RS06845	COG1033	growth of symbiont in host cell
CEW82_RS06855	COG2357	RelA SpoT domain protein
CEW82_RS06865	COG0277	FAD linked oxidase domain protein
CEW82_RS06870	COG1316	TRANSCRIPTIONal
CEW82_RS06890	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CEW82_RS06895	COG0517	IMP dehydrogenase activity
CEW82_RS06895	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
CEW82_RS06905	COG0745	RESPONSE REGULATOR receiver
CEW82_RS06910	COG5002	protein histidine kinase activity
CEW82_RS06930	COG1914	H( )-stimulated, divalent metal cation uptake system
CEW82_RS06935	COG1309	transcriptional regulator
CEW82_RS06940	COG1959	2 iron, 2 sulfur cluster binding
CEW82_RS06955	COG0163	prenyltransferase activity
CEW82_RS06965	COG0463	Glycosyl transferase, family 2
CEW82_RS06965	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
CEW82_RS06970	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
CEW82_RS06975	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
CEW82_RS06980	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
CEW82_RS06990	COG1263	PTS System
CEW82_RS06990	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CEW82_RS06990	COG2190	(PTS) system
CEW82_RS06995	COG2190	(PTS) system
CEW82_RS06995	COG1263	PTS System
CEW82_RS06995	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CEW82_RS07000	COG0366	Alpha amylase catalytic
CEW82_RS07005	COG2188	Transcriptional regulator
CEW82_RS07040	COG1131	(ABC) transporter
CEW82_RS07045	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CEW82_RS07050	COG0626	cystathionine gamma-synthase activity
CEW82_RS07055	COG1045	serine acetyltransferase
CEW82_RS07070	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CEW82_RS07075	COG0431	NADPH-dependent FMN reductase
CEW82_RS07115	COG3118	belongs to the thioredoxin family
CEW82_RS07125	COG0246	Mannitol dehydrogenase
CEW82_RS07130	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
CEW82_RS07140	COG2213	PTS system mannitol-specific
CEW82_RS07170	COG0363	glucosamine-6-phosphate deaminase activity
CEW82_RS07185	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CEW82_RS07205	COG0386	Belongs to the glutathione peroxidase family
CEW82_RS07215	COG1122	ATPase activity
CEW82_RS07225	COG0488	(ABC) transporter
CEW82_RS07230	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CEW82_RS07235	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CEW82_RS07265	COG0667	Aldo Keto reductase
CEW82_RS07275	COG1132	(ABC) transporter
CEW82_RS07280	COG0406	alpha-ribazole phosphatase activity
CEW82_RS07285	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
CEW82_RS07290	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CEW82_RS07295	COG4166	transmembrane transport
CEW82_RS07300	COG4166	transmembrane transport
CEW82_RS07320	COG1757	Na H antiporter
CEW82_RS07325	COG1063	alcohol dehydrogenase
CEW82_RS07385	COG3842	ATPase activity
CEW82_RS07410	COG0366	Alpha amylase catalytic
CEW82_RS07415	COG0366	Alpha amylase catalytic
CEW82_RS07420	COG1609	Transcriptional regulator
CEW82_RS07425	COG1609	Transcriptional regulator
CEW82_RS07435	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
CEW82_RS07440	COG1461	Dihydroxyacetone kinase
CEW82_RS07445	COG2376	Dihydroxyacetone kinase
CEW82_RS07450	COG2376	Dihydroxyacetone kinase
CEW82_RS07455	COG1309	transcriptional regulator
CEW82_RS07460	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
CEW82_RS07465	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
CEW82_RS07480	COG1131	(ABC) transporter
CEW82_RS07505	COG2188	Transcriptional regulator
CEW82_RS07515	COG4720	Psort location CytoplasmicMembrane, score
CEW82_RS07520	COG1122	ATPase activity
CEW82_RS07525	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
CEW82_RS07530	COG2814	Major facilitator Superfamily
CEW82_RS07535	COG1733	regulation of RNA biosynthetic process
CEW82_RS07580	COG0667	Aldo Keto reductase
CEW82_RS07585	COG0656	L-ascorbic acid biosynthetic process
CEW82_RS07590	COG2807	transmembrane transport
CEW82_RS07595	COG0640	Transcriptional regulator
CEW82_RS07620	COG1983	PspC domain protein
CEW82_RS07625	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
CEW82_RS07630	COG2337	Toxic component of a toxin-antitoxin (TA) module
CEW82_RS07650	COG1113	amino acid transport
CEW82_RS07665	COG1733	regulation of RNA biosynthetic process
CEW82_RS07670	COG0604	alcohol dehydrogenase
CEW82_RS07675	COG1263	PTS System
CEW82_RS07675	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CEW82_RS07675	COG2190	(PTS) system
CEW82_RS07690	COG2190	(PTS) system
CEW82_RS07695	COG3976	FMN-binding domain protein
CEW82_RS07695	COG1053	succinate dehydrogenase
CEW82_RS07700	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
CEW82_RS07710	COG0352	thiamine-phosphate diphosphorylase activity
CEW82_RS07715	COG0351	phosphomethylpyrimidine kinase
CEW82_RS07720	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
CEW82_RS07730	COG1606	tRNA processing
CEW82_RS07735	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
CEW82_RS07740	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
CEW82_RS07745	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
CEW82_RS07750	COG1691	(AIR) carboxylase
CEW82_RS07755	COG3875	lactate racemase activity
CEW82_RS07760	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CEW82_RS07765	COG0310	cobalt ion transport
CEW82_RS07770	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
CEW82_RS07775	COG1122	ATPase activity
CEW82_RS07805	COG4166	transmembrane transport
CEW82_RS07820	COG3022	response to hydroperoxide
CEW82_RS07825	COG2267	carboxylic ester hydrolase activity
CEW82_RS07840	COG3321	synthase
CEW82_RS07840	COG0604	alcohol dehydrogenase
CEW82_RS07855	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
CEW82_RS07880	COG2368	4-hydroxyphenylacetate
CEW82_RS07885	COG2365	Tyrosine phosphatase family
CEW82_RS07900	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CEW82_RS07905	COG2508	Transcriptional regulator
CEW82_RS07915	COG0778	Nitroreductase
CEW82_RS07925	COG1028	Short-chain dehydrogenase reductase Sdr
CEW82_RS07930	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CEW82_RS07960	COG1573	uracil-dna glycosylase
CEW82_RS07975	COG1301	dicarboxylic acid transport
CEW82_RS07985	COG2169	Transcriptional regulator
CEW82_RS07985	COG1917	Cupin 2, conserved barrel domain protein
CEW82_RS08045	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
CEW82_RS08050	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CEW82_RS08055	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
CEW82_RS08060	COG4853	Protein conserved in bacteria
CEW82_RS08070	COG5002	protein histidine kinase activity
CEW82_RS08075	COG0745	RESPONSE REGULATOR receiver
CEW82_RS08090	COG1278	Cold shock
CEW82_RS08100	COG1554	hydrolase, family 65, central catalytic
CEW82_RS08105	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CEW82_RS08110	COG0561	phosphatase activity
CEW82_RS08120	COG0058	SHG alpha-glucan phosphorylase activity
CEW82_RS08130	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
CEW82_RS08135	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
CEW82_RS08140	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
CEW82_RS08145	COG4166	transmembrane transport
CEW82_RS08150	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
CEW82_RS08155	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
CEW82_RS08160	COG2814	Major facilitator Superfamily
CEW82_RS08165	COG0305	Participates in initiation and elongation during chromosome replication
CEW82_RS08170	COG0359	binds to the 23S rRNA
CEW82_RS08180	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
CEW82_RS08185	COG0629	single-stranded DNA binding
CEW82_RS08190	COG0360	Binds together with S18 to 16S ribosomal RNA
CEW82_RS08205	COG0187	DNA topoisomerase II activity
CEW82_RS08210	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
CEW82_RS08215	COG2501	S4 domain
CEW82_RS08220	COG0592	DNA-directed DNA polymerase activity
CEW82_RS08225	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
CEW82_RS08230	COG0230	Belongs to the bacterial ribosomal protein bL34 family
CEW82_RS08235	COG0594	ribonuclease P activity
CEW82_RS08240	COG0706	membrane insertase activity
CEW82_RS08245	COG4166	transmembrane transport
CEW82_RS08260	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
CEW82_RS08265	COG0445	tRNA wobble uridine modification
CEW82_RS08270	COG0681	Belongs to the peptidase S26 family
CEW82_RS08285	COG1307	EDD domain protein, DegV family
CEW82_RS08300	COG3479	Phenolic acid decarboxylase
CEW82_RS08305	COG1695	Transcriptional regulator
CEW82_RS08315	COG1012	belongs to the aldehyde dehydrogenase family
CEW82_RS08315	COG1454	alcohol dehydrogenase
CEW82_RS08330	COG1609	Transcriptional regulator
CEW82_RS08340	COG1869	D-ribose catabolic process
CEW82_RS08345	COG4975	Glucose uptake
CEW82_RS08365	COG3730	PTS system glucitol sorbitol-specific
CEW82_RS08370	COG3732	PTS system glucitol sorbitol-specific
CEW82_RS08385	COG1228	amidohydrolase
CEW82_RS08400	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
CEW82_RS08405	COG1737	Transcriptional regulator
CEW82_RS08410	COG1609	Transcriptional regulator
CEW82_RS08430	COG2160	L-arabinose isomerase activity
CEW82_RS08435	COG0110	maltose O-acetyltransferase activity
CEW82_RS08440	COG0546	phosphoglycolate phosphatase activity
CEW82_RS08445	COG1349	DNA-binding transcription factor activity
CEW82_RS08460	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CEW82_RS08470	COG3716	PTS system mannose fructose sorbose family IID component
CEW82_RS08475	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CEW82_RS08480	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
CEW82_RS08515	COG3964	amidohydrolase
CEW82_RS08530	COG0800	Aldolase
CEW82_RS08535	COG1028	Short-chain dehydrogenase reductase Sdr
CEW82_RS08550	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
CEW82_RS08555	COG1609	Transcriptional regulator
CEW82_RS08560	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CEW82_RS08570	COG3715	PTS system
CEW82_RS08575	COG3716	PTS system mannose fructose sorbose family IID component
CEW82_RS08580	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CEW82_RS08585	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
CEW82_RS08600	COG1653	transport
CEW82_RS08605	COG2207	Transcriptional regulator
CEW82_RS08610	COG2211	Major facilitator Superfamily
CEW82_RS08620	COG2755	lipolytic protein G-D-S-L family
CEW82_RS08630	COG1609	Transcriptional regulator
CEW82_RS08650	COG1312	Catalyzes the dehydration of D-mannonate
CEW82_RS08655	COG0246	Mannitol dehydrogenase
CEW82_RS08670	COG1904	glucuronate isomerase
CEW82_RS08680	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CEW82_RS08695	COG0477	Major facilitator Superfamily
CEW82_RS08700	COG1063	alcohol dehydrogenase
CEW82_RS08710	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
CEW82_RS08715	COG2211	Major facilitator Superfamily
CEW82_RS08730	COG1609	Transcriptional regulator
CEW82_RS08740	COG1904	glucuronate isomerase
CEW82_RS08765	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
CEW82_RS08765	COG3933	PFAM sigma-54 factor interaction domain-containing protein
CEW82_RS08775	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CEW82_RS08775	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
CEW82_RS08785	COG3716	PTS system mannose fructose sorbose family IID component
CEW82_RS08790	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
CEW82_RS08795	COG0561	phosphatase activity
CEW82_RS08800	COG3507	Belongs to the glycosyl hydrolase 43 family
CEW82_RS08805	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
CEW82_RS08810	COG2211	Major facilitator Superfamily
CEW82_RS08835	COG1070	Carbohydrate kinase
CEW82_RS08840	COG3254	rhamnose metabolic process
CEW82_RS08845	COG4806	L-rhamnose isomerase
CEW82_RS08850	COG0235	Class ii aldolase
CEW82_RS08865	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
CEW82_RS08865	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CEW82_RS08875	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CEW82_RS08880	COG1609	Transcriptional regulator
CEW82_RS08890	COG1263	PTS System
CEW82_RS08890	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CEW82_RS08890	COG2190	(PTS) system
CEW82_RS08895	COG2723	6-phospho-beta-galactosidase activity
CEW82_RS08900	COG2723	6-phospho-beta-galactosidase activity
CEW82_RS08905	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CEW82_RS08915	COG3716	PTS system mannose fructose sorbose family IID component
CEW82_RS08925	COG0366	Alpha amylase catalytic
CEW82_RS08940	COG2971	BadF BadG BcrA BcrD
CEW82_RS08945	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
CEW82_RS08950	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CEW82_RS08955	COG2188	Transcriptional regulator
CEW82_RS08960	COG2267	carboxylic ester hydrolase activity
CEW82_RS08970	COG2271	Major facilitator Superfamily
CEW82_RS08985	COG1028	Short-chain dehydrogenase reductase Sdr
CEW82_RS09000	COG2271	Major facilitator Superfamily
CEW82_RS09005	COG0583	DNA-binding transcription factor activity
CEW82_RS09010	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CEW82_RS09015	COG0710	3-dehydroquinate dehydratase activity
CEW82_RS09035	COG3507	Belongs to the glycosyl hydrolase 43 family
CEW82_RS09040	COG3250	beta-galactosidase activity
CEW82_RS09050	COG1917	Cupin 2, conserved barrel domain protein
CEW82_RS09050	COG2207	Transcriptional regulator
CEW82_RS09060	COG3250	beta-galactosidase activity
CEW82_RS09075	COG0667	Aldo Keto reductase
CEW82_RS09080	COG1609	Transcriptional regulator
CEW82_RS09090	COG2190	(PTS) system
CEW82_RS09090	COG2211	Major facilitator Superfamily
CEW82_RS09110	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
CEW82_RS09115	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CEW82_RS09120	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
CEW82_RS09125	COG1609	Transcriptional regulator
CEW82_RS09145	COG2944	sequence-specific DNA binding
CEW82_RS09150	COG2184	nucleotidyltransferase activity
CEW82_RS09160	COG1609	Transcriptional regulator
CEW82_RS09165	COG1874	Beta-galactosidase
CEW82_RS09175	COG1114	Component of the transport system for branched-chain amino acids
CEW82_RS09195	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
CEW82_RS09245	COG0446	pyridine nucleotide-disulphide oxidoreductase
CEW82_RS09255	COG3590	peptidase
CEW82_RS09260	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CEW82_RS09290	COG1937	Protein conserved in bacteria
CEW82_RS09295	COG3118	belongs to the thioredoxin family
CEW82_RS09305	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
CEW82_RS09310	COG2217	Heavy metal translocating P-type atpase
CEW82_RS09325	COG2226	methyltransferase
CEW82_RS09375	COG0791	NLP P60 protein
CEW82_RS09375	COG1388	LysM domain
CEW82_RS09375	COG3103	Sh3 type 3 domain protein
CEW82_RS09375	COG1388	LysM domain
CEW82_RS09375	COG0791	NLP P60 protein
CEW82_RS09375	COG3103	Sh3 type 3 domain protein
CEW82_RS09425	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
CEW82_RS09430	COG1968	undecaprenyl-diphosphatase activity
CEW82_RS09455	COG0656	L-ascorbic acid biosynthetic process
CEW82_RS09465	COG0679	Auxin Efflux Carrier
CEW82_RS09470	COG0737	Belongs to the 5'-nucleotidase family
CEW82_RS09525	COG0477	Major facilitator Superfamily
CEW82_RS09540	COG3682	Transcriptional regulator
CEW82_RS09550	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
CEW82_RS09565	COG0697	spore germination
CEW82_RS09605	COG1194	a g-specific adenine glycosylase
CEW82_RS09615	COG3189	MarR family transcriptional regulator
CEW82_RS09620	COG1393	Belongs to the ArsC family
CEW82_RS09635	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
CEW82_RS09645	COG1113	amino acid transport
CEW82_RS09650	COG1757	Na H antiporter
CEW82_RS09655	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CEW82_RS09660	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
CEW82_RS09675	COG2217	Heavy metal translocating P-type atpase
CEW82_RS09710	COG4989	oxidoreductase activity
CEW82_RS09715	COG0477	Major facilitator Superfamily
CEW82_RS09720	COG2151	metal-sulfur cluster biosynthetic enzyme
CEW82_RS09725	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
CEW82_RS09735	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CEW82_RS09770	COG2814	Major facilitator Superfamily
CEW82_RS09775	COG0803	Belongs to the bacterial solute-binding protein 9 family
CEW82_RS09815	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CEW82_RS09820	COG0302	gtp cyclohydrolase
CEW82_RS09830	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
CEW82_RS09840	COG0519	Catalyzes the synthesis of GMP from XMP
CEW82_RS09865	COG0640	Transcriptional regulator
CEW82_RS09870	COG1272	protein, Hemolysin III
CEW82_RS09885	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
CEW82_RS09890	COG0628	permease
CEW82_RS09920	COG0531	amino acid
CEW82_RS09930	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CEW82_RS09935	COG2365	Tyrosine phosphatase family
CEW82_RS09940	COG4166	transmembrane transport
CEW82_RS09945	COG0601	transmembrane transport
CEW82_RS09950	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CEW82_RS09955	COG0444	Belongs to the ABC transporter superfamily
CEW82_RS09965	COG0516	GMP reductase activity
CEW82_RS09970	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
CEW82_RS09975	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CEW82_RS09985	COG1929	Belongs to the glycerate kinase type-1 family
CEW82_RS10000	COG2738	Putative neutral zinc metallopeptidase
CEW82_RS10010	COG1307	EDD domain protein, DegV family
CEW82_RS10020	COG1380	Effector of murein hydrolase LrgA
CEW82_RS10025	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CEW82_RS10050	COG0800	Aldolase
CEW82_RS10060	COG3414	Phosphotransferase system galactitol-specific IIB component
CEW82_RS10065	COG3775	system Galactitol-specific IIC component
CEW82_RS10070	COG4948	Mandelate Racemase Muconate Lactonizing
CEW82_RS10080	COG0735	belongs to the Fur family
CEW82_RS10110	COG1263	PTS System
CEW82_RS10110	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CEW82_RS10110	COG2190	(PTS) system
CEW82_RS10125	COG0561	phosphatase activity
CEW82_RS10140	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CEW82_RS10145	COG4619	ABC transporter
CEW82_RS10150	COG0390	transport system, permease component
CEW82_RS10160	COG0481	GTPase activity
CEW82_RS10170	COG1609	Transcriptional regulator
CEW82_RS10175	COG0366	Alpha amylase catalytic
CEW82_RS10180	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CEW82_RS10180	COG1263	PTS System
CEW82_RS10180	COG2190	(PTS) system
CEW82_RS10185	COG1373	ATPase (AAA superfamily
CEW82_RS10215	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CEW82_RS10220	COG1126	abc transporter atp-binding protein
CEW82_RS10225	COG0765	amino acid transport
CEW82_RS10230	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CEW82_RS10235	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CEW82_RS10240	COG0583	DNA-binding transcription factor activity
CEW82_RS10255	COG0463	Glycosyl transferase, family 2
CEW82_RS10265	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CEW82_RS10270	COG0357	Ribosomal RNA small subunit methyltransferase G
CEW82_RS10280	COG1192	Involved in chromosome partitioning
CEW82_RS10285	COG1475	DNA binding
CEW82_RS10290	COG4481	Protein conserved in bacteria
CEW82_RS10295	COG0012	GTP binding
CEW82_RS10310	COG0517	IMP dehydrogenase activity
CEW82_RS10310	COG0516	GMP reductase activity
CEW82_RS10325	COG1686	Belongs to the peptidase S11 family
CEW82_RS10340	COG1247	-acetyltransferase
CEW82_RS10375	COG0515	serine threonine protein kinase
CEW82_RS10375	COG2815	serine threonine protein kinase
CEW82_RS10385	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CEW82_RS10395	COG1846	Transcriptional regulator
CEW82_RS10395	COG1940	carbohydrate kinase activity
CEW82_RS10400	COG0628	permease
CEW82_RS10405	COG0588	phosphoglycerate mutase activity
CEW82_RS10410	COG2226	methyltransferase
CEW82_RS10430	COG1511	domain protein
CEW82_RS10465	COG2226	methyltransferase
CEW82_RS10475	COG1053	succinate dehydrogenase
CEW82_RS10480	COG0583	DNA-binding transcription factor activity
CEW82_RS10495	COG1940	carbohydrate kinase activity
CEW82_RS10515	COG1028	Short-chain dehydrogenase reductase Sdr
CEW82_RS10520	COG4975	Glucose uptake
CEW82_RS10525	COG0110	maltose O-acetyltransferase activity
CEW82_RS10545	COG0025	NhaP-type Na H and K H
CEW82_RS10560	COG1064	alcohol dehydrogenase
CEW82_RS10575	COG0300	oxidoreductase activity
CEW82_RS10585	COG0583	DNA-binding transcription factor activity
CEW82_RS10600	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
CEW82_RS10695	COG1733	regulation of RNA biosynthetic process
CEW82_RS10700	COG2190	(PTS) system
CEW82_RS10700	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CEW82_RS10700	COG1263	PTS System
CEW82_RS10705	COG2723	6-phospho-beta-galactosidase activity
CEW82_RS10710	COG3711	transcriptional antiterminator
CEW82_RS10715	COG0583	DNA-binding transcription factor activity
CEW82_RS10720	COG3976	FMN-binding domain protein
CEW82_RS10720	COG0431	NADPH-dependent FMN reductase
CEW82_RS10720	COG1053	succinate dehydrogenase
CEW82_RS10725	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CEW82_RS10745	COG0789	Transcriptional regulator
CEW82_RS10780	COG2816	NAD+ diphosphatase activity
CEW82_RS10800	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CEW82_RS10835	COG0110	maltose O-acetyltransferase activity
CEW82_RS10845	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CEW82_RS10850	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CEW82_RS10855	COG1120	ATPase activity
CEW82_RS10860	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
CEW82_RS10885	COG4989	oxidoreductase activity
CEW82_RS10910	COG4221	oxidoreductase activity
CEW82_RS10915	COG1733	regulation of RNA biosynthetic process
CEW82_RS10935	COG1012	belongs to the aldehyde dehydrogenase family
CEW82_RS10940	COG1090	epimerase
CEW82_RS10945	COG1309	transcriptional regulator
CEW82_RS10960	COG0367	asparagine synthase
CEW82_RS10965	COG1376	ErfK ybiS ycfS ynhG family protein
CEW82_RS10970	COG2814	Major facilitator Superfamily
CEW82_RS10975	COG1733	regulation of RNA biosynthetic process
CEW82_RS11070	COG2217	Heavy metal translocating P-type atpase
CEW82_RS11090	COG0531	amino acid
CEW82_RS11110	COG1028	Short-chain dehydrogenase reductase Sdr
CEW82_RS11115	COG1473	amidohydrolase
CEW82_RS11125	COG1132	(ABC) transporter
CEW82_RS11130	COG1132	(ABC) transporter
CEW82_RS11145	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CEW82_RS11155	COG3706	GGDEF domain
CEW82_RS11180	COG0741	lytic transglycosylase activity
CEW82_RS11185	COG0741	lytic transglycosylase activity
CEW82_RS11190	COG0789	Transcriptional regulator
CEW82_RS11200	COG2723	6-phospho-beta-galactosidase activity
CEW82_RS11205	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CEW82_RS11210	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CEW82_RS11245	COG0577	efflux transmembrane transporter activity
CEW82_RS11245	COG1136	(ABC) transporter
CEW82_RS11255	COG0640	Transcriptional regulator
CEW82_RS11275	COG1914	H( )-stimulated, divalent metal cation uptake system
CEW82_RS11295	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CEW82_RS11295	COG5549	protein import
CEW82_RS11325	COG0410	ABC transporter
CEW82_RS11330	COG0517	IMP dehydrogenase activity
CEW82_RS11360	COG4120	Belongs to the binding-protein-dependent transport system permease family
CEW82_RS11365	COG1116	anion transmembrane transporter activity
CEW82_RS11370	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CEW82_RS11370	COG2190	(PTS) system
CEW82_RS11370	COG1263	PTS System
CEW82_RS11375	COG0778	Nitroreductase
CEW82_RS11405	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
CEW82_RS11405	COG2755	lipolytic protein G-D-S-L family
CEW82_RS11410	COG0697	spore germination
CEW82_RS11415	COG4932	domain protein
CEW82_RS11430	COG1609	Transcriptional regulator
CEW82_RS11440	COG3959	Transketolase, thiamine diphosphate binding domain
CEW82_RS11445	COG3958	Transketolase
CEW82_RS11450	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CEW82_RS11455	COG3775	system Galactitol-specific IIC component
CEW82_RS11475	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
CEW82_RS11485	COG0583	DNA-binding transcription factor activity
CEW82_RS11500	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CEW82_RS11515	COG0242	peptide deformylase activity
CEW82_RS11525	COG1328	CTP reductase activity
CEW82_RS11530	COG0602	queuosine metabolic process
CEW82_RS11535	COG5001	Diguanylate cyclase
CEW82_RS11535	COG3300	MHYT domain
CEW82_RS11575	COG2270	Major facilitator Superfamily
CEW82_RS11580	COG0531	amino acid
CEW82_RS11585	COG2267	carboxylic ester hydrolase activity
CEW82_RS11605	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CEW82_RS11620	COG0488	(ABC) transporter
CEW82_RS11650	COG0640	Transcriptional regulator
CEW82_RS11660	COG1511	domain protein
CEW82_RS11660	COG1511	domain protein
CEW82_RS11670	COG2814	Major facilitator Superfamily
CEW82_RS11675	COG1132	(ABC) transporter
CEW82_RS11680	COG1132	(ABC) transporter
CEW82_RS11685	COG0667	Aldo Keto reductase
CEW82_RS11695	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
CEW82_RS11725	COG1011	Hydrolase
CEW82_RS11730	COG0110	maltose O-acetyltransferase activity
CEW82_RS11735	COG0589	response to stress
CEW82_RS11745	COG1396	sequence-specific DNA binding
CEW82_RS11750	COG0477	Major facilitator Superfamily
CEW82_RS11770	COG0456	acetyltransferase
CEW82_RS11780	COG0681	Belongs to the peptidase S26 family
CEW82_RS11810	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CEW82_RS11820	COG0789	Transcriptional regulator
CEW82_RS11835	COG4221	oxidoreductase activity
CEW82_RS11845	COG4152	abc transporter atp-binding protein
CEW82_RS11850	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CEW82_RS11865	COG0438	transferase activity, transferring glycosyl groups
CEW82_RS11880	COG0583	DNA-binding transcription factor activity
CEW82_RS11885	COG2855	membrane
CEW82_RS11890	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CEW82_RS11905	COG2814	Major facilitator Superfamily
CEW82_RS11910	COG2814	Major facilitator Superfamily
CEW82_RS11955	COG1136	(ABC) transporter
CEW82_RS11960	COG0577	efflux transmembrane transporter activity
CEW82_RS11975	COG1811	Na channel or pump
CEW82_RS11990	COG4990	cell redox homeostasis
CEW82_RS12005	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CEW82_RS12010	COG4720	Psort location CytoplasmicMembrane, score
CEW82_RS12035	COG0583	DNA-binding transcription factor activity
CEW82_RS12045	COG0656	L-ascorbic acid biosynthetic process
CEW82_RS12055	COG0531	amino acid
CEW82_RS12080	COG0716	FMN binding
CEW82_RS12105	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CEW82_RS12110	COG0561	phosphatase activity
CEW82_RS12130	COG1216	Glycosyl transferase, family 2
CEW82_RS12135	COG2188	Transcriptional regulator
CEW82_RS12140	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CEW82_RS12145	COG1447	Phosphotransferase system cellobiose-specific component IIA
CEW82_RS12150	COG2723	6-phospho-beta-galactosidase activity
CEW82_RS12155	COG2723	6-phospho-beta-galactosidase activity
CEW82_RS12160	COG3048	D-serine ammonia-lyase activity
CEW82_RS12180	COG3730	PTS system glucitol sorbitol-specific
CEW82_RS12185	COG3732	PTS system glucitol sorbitol-specific
CEW82_RS12205	COG1309	transcriptional regulator
CEW82_RS12210	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
CEW82_RS12215	COG1827	regulation of RNA biosynthetic process
CEW82_RS12220	COG1942	4-Oxalocrotonate Tautomerase
CEW82_RS12255	COG0494	nUDIX hydrolase
CEW82_RS12260	COG0110	maltose O-acetyltransferase activity
CEW82_RS12270	COG0561	phosphatase activity
CEW82_RS12280	COG0366	Alpha amylase catalytic
CEW82_RS12300	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
CEW82_RS12320	COG2246	polysaccharide biosynthetic process
CEW82_RS12335	COG0589	response to stress
CEW82_RS12345	COG1131	(ABC) transporter
CEW82_RS12350	COG1725	Transcriptional regulator
CEW82_RS12365	COG1136	(ABC) transporter
CEW82_RS12380	COG3338	carbonate dehydratase activity
CEW82_RS12385	COG2365	Tyrosine phosphatase family
CEW82_RS12390	COG0095	Lipoate-protein ligase
CEW82_RS12400	COG0431	NADPH-dependent FMN reductase
CEW82_RS12400	COG3976	FMN-binding domain protein
CEW82_RS12400	COG1053	succinate dehydrogenase
CEW82_RS12405	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
CEW82_RS12410	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
CEW82_RS12415	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
CEW82_RS12420	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CEW82_RS12425	COG0047	phosphoribosylformylglycinamidine synthase activity
CEW82_RS12430	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CEW82_RS12440	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
CEW82_RS12445	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
CEW82_RS12450	COG0138	bifunctional purine biosynthesis protein purh
CEW82_RS12455	COG0151	Belongs to the GarS family
CEW82_RS12470	COG2252	PERMEase
CEW82_RS12475	COG2233	PERMEase
CEW82_RS12480	COG2508	Transcriptional regulator
CEW82_RS12490	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
CEW82_RS12495	COG0540	Belongs to the ATCase OTCase family
CEW82_RS12500	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
CEW82_RS12505	COG0505	Belongs to the CarA family
CEW82_RS12510	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
CEW82_RS12515	COG0167	dihydroorotate dehydrogenase activity
CEW82_RS12520	COG0284	orotidine-5'-phosphate decarboxylase activity
CEW82_RS12525	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
CEW82_RS12535	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
CEW82_RS12540	COG1074	ATP-dependent DNA helicase activity
CEW82_RS12550	COG0702	epimerase
CEW82_RS12555	COG0583	DNA-binding transcription factor activity
CEW82_RS12570	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CEW82_RS12575	COG0436	Aminotransferase
CEW82_RS12585	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
CEW82_RS12595	COG2814	Major facilitator Superfamily
CEW82_RS12605	COG1780	Probably involved in ribonucleotide reductase function
CEW82_RS12610	COG1253	flavin adenine dinucleotide binding
CEW82_RS12655	COG1418	mRNA catabolic process
CEW82_RS12670	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CEW82_RS12675	COG2188	Transcriptional regulator
CEW82_RS12685	COG0438	transferase activity, transferring glycosyl groups
CEW82_RS12700	COG1396	sequence-specific DNA binding
CEW82_RS12720	COG0564	pseudouridine synthase activity
CEW82_RS12735	COG2188	Transcriptional regulator
CEW82_RS12740	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CEW82_RS12745	COG3715	PTS system
CEW82_RS12750	COG3716	PTS system mannose fructose sorbose family IID component
CEW82_RS12760	COG1705	Flagellar rod assembly protein muramidase FlgJ
CEW82_RS12765	COG0095	Lipoate-protein ligase
CEW82_RS12785	COG0789	Transcriptional regulator
CEW82_RS12815	COG0626	cystathionine gamma-synthase activity
CEW82_RS12820	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CEW82_RS12825	COG1073	alpha beta
CEW82_RS12835	COG0028	Belongs to the TPP enzyme family
CEW82_RS12880	COG2186	Transcriptional regulator
CEW82_RS12885	COG1131	(ABC) transporter
CEW82_RS12895	COG1335	isochorismatase
CEW82_RS12905	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
CEW82_RS12910	COG0673	inositol 2-dehydrogenase activity
CEW82_RS12915	COG0673	inositol 2-dehydrogenase activity
CEW82_RS12920	COG1737	Transcriptional regulator
CEW82_RS12925	COG1609	Transcriptional regulator
CEW82_RS12930	COG0561	phosphatase activity
CEW82_RS12935	COG0328	RNA-DNA hybrid ribonuclease activity
CEW82_RS12955	COG0778	Nitroreductase
CEW82_RS12960	COG2326	polyphosphate kinase activity
CEW82_RS12975	COG0492	ferredoxin-NADP+ reductase activity
CEW82_RS12980	COG0584	glycerophosphoryl diester phosphodiesterase
CEW82_RS12985	COG1368	sulfuric ester hydrolase activity
CEW82_RS12990	COG0454	-acetyltransferase
CEW82_RS13010	COG3548	integral membrane protein
CEW82_RS13030	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
CEW82_RS13035	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CEW82_RS13055	COG1132	(ABC) transporter
CEW82_RS13060	COG1132	(ABC) transporter
CEW82_RS13070	COG0300	oxidoreductase activity
CEW82_RS13095	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
CEW82_RS13100	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
CEW82_RS13105	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
CEW82_RS13110	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
CEW82_RS13115	COG0131	Imidazoleglycerol-phosphate dehydratase
CEW82_RS13120	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
CEW82_RS13125	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
CEW82_RS13130	COG0107	imidazoleglycerol-phosphate synthase activity
CEW82_RS13135	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
CEW82_RS13140	COG0140	phosphoribosyl-ATP diphosphatase activity
CEW82_RS13145	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CEW82_RS13150	COG0110	maltose O-acetyltransferase activity
CEW82_RS13155	COG0861	Integral membrane protein TerC family
CEW82_RS13160	COG2084	Dehydrogenase
CEW82_RS13165	COG0446	pyridine nucleotide-disulphide oxidoreductase
CEW82_RS13175	COG4120	Belongs to the binding-protein-dependent transport system permease family
CEW82_RS13195	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
CEW82_RS13200	COG2873	o-acetylhomoserine
CEW82_RS13210	COG1307	EDD domain protein, DegV family
CEW82_RS13215	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CEW82_RS13220	COG1263	PTS System
CEW82_RS13220	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CEW82_RS13220	COG2190	(PTS) system
CEW82_RS13235	COG0488	(ABC) transporter
CEW82_RS13240	COG1131	(ABC) transporter
CEW82_RS13250	COG5001	Diguanylate cyclase
CEW82_RS13250	COG3300	MHYT domain
CEW82_RS13265	COG1522	sequence-specific DNA binding
CEW82_RS13270	COG0791	NLP P60 protein
CEW82_RS13290	COG0477	Major facilitator Superfamily
CEW82_RS13330	COG3830	Belongs to the UPF0237 family
CEW82_RS13335	COG2848	UPF0210 protein
CEW82_RS13340	COG0745	RESPONSE REGULATOR receiver
CEW82_RS13345	COG3850	Histidine kinase
CEW82_RS13345	COG5002	protein histidine kinase activity
CEW82_RS13350	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
CEW82_RS13355	COG4975	Glucose uptake
CEW82_RS13360	COG0166	Belongs to the GPI family
CEW82_RS13375	COG0577	efflux transmembrane transporter activity
CEW82_RS13375	COG1136	(ABC) transporter
CEW82_RS13380	COG0438	transferase activity, transferring glycosyl groups
CEW82_RS13385	COG1132	(ABC) transporter
CEW82_RS13430	COG4886	Leucine-rich repeat (LRR) protein
CEW82_RS13430	COG4932	domain protein
CEW82_RS13470	COG0726	polysaccharide deacetylase
CEW82_RS13485	COG1132	(ABC) transporter
CEW82_RS13500	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CEW82_RS13510	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CEW82_RS13515	COG1482	cell wall glycoprotein biosynthetic process
CEW82_RS13520	COG3442	glutamine amidotransferase
CEW82_RS13525	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
CEW82_RS13530	COG1435	thymidine kinase activity
CEW82_RS13535	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
CEW82_RS13540	COG2890	protein-(glutamine-N5) methyltransferase activity
CEW82_RS13545	COG0009	L-threonylcarbamoyladenylate synthase
CEW82_RS13550	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
CEW82_RS13555	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
CEW82_RS13560	COG2233	PERMEase
CEW82_RS13565	COG0356	it plays a direct role in the translocation of protons across the membrane
CEW82_RS13570	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CEW82_RS13575	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
CEW82_RS13580	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CEW82_RS13585	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
CEW82_RS13590	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
CEW82_RS13595	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
CEW82_RS13600	COG0355	proton-transporting ATP synthase activity, rotational mechanism
CEW82_RS13605	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CEW82_RS13610	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CEW82_RS13615	COG1077	Cell shape determining protein MreB Mrl
CEW82_RS13620	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
CEW82_RS13630	COG0772	Belongs to the SEDS family
CEW82_RS13635	COG0509	glycine decarboxylation via glycine cleavage system
CEW82_RS13640	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CEW82_RS13645	COG2011	ABC-type metal ion transport system permease component
CEW82_RS13650	COG1464	Belongs to the NlpA lipoprotein family
CEW82_RS13670	COG1181	Belongs to the D-alanine--D-alanine ligase family
CEW82_RS13685	COG0589	response to stress
CEW82_RS13700	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CEW82_RS13705	COG2918	glutathione biosynthetic process
CEW82_RS13705	COG0189	ligase activity
CEW82_RS13710	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
CEW82_RS13715	COG1984	allophanate hydrolase subunit 2
CEW82_RS13720	COG0511	ligase activity, forming carbon-carbon bonds
CEW82_RS13725	COG0439	Biotin carboxylase
CEW82_RS13730	COG4336	lyase activity
CEW82_RS13735	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
CEW82_RS13745	COG0640	Transcriptional regulator
CEW82_RS13760	COG4493	Belongs to the UPF0637 family
CEW82_RS13775	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
CEW82_RS13780	COG1956	GAF domain-containing protein
CEW82_RS13785	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
CEW82_RS13790	COG1104	cysteine desulfurase activity
CEW82_RS13795	COG0301	tRNA thio-modification
CEW82_RS13805	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
CEW82_RS13810	COG0525	valine-tRNA ligase activity
CEW82_RS13815	COG0285	dihydrofolate synthase activity
CEW82_RS13820	COG2003	Belongs to the UPF0758 family
CEW82_RS13825	COG1077	Cell shape determining protein MreB Mrl
CEW82_RS13830	COG1792	Involved in formation and maintenance of cell shape
CEW82_RS13845	COG2894	cell division
CEW82_RS13850	COG0765	amino acid transport
CEW82_RS13855	COG1126	abc transporter atp-binding protein
CEW82_RS13860	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CEW82_RS13865	COG0527	aspartate kinase activity
CEW82_RS13870	COG0612	Peptidase, M16
CEW82_RS13875	COG0612	Peptidase, M16
CEW82_RS13880	COG1426	Protein conserved in bacteria
CEW82_RS13885	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CEW82_RS13890	COG1058	Belongs to the CinA family
CEW82_RS13890	COG1546	Belongs to the CinA family
CEW82_RS13900	COG1418	mRNA catabolic process
CEW82_RS13905	COG1692	metallophosphoesterase
CEW82_RS13910	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
CEW82_RS13915	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
CEW82_RS13940	COG0632	four-way junction helicase activity
CEW82_RS13945	COG2255	four-way junction helicase activity
CEW82_RS13950	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
CEW82_RS13955	COG0343	queuine tRNA-ribosyltransferase activity
CEW82_RS13960	COG1862	Preprotein translocase
CEW82_RS13965	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CEW82_RS13970	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
CEW82_RS13975	COG0513	Belongs to the DEAD box helicase family
CEW82_RS13980	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CEW82_RS13990	COG4472	Bacterial protein of unknown function (DUF965)
CEW82_RS13995	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
CEW82_RS14000	COG3906	Belongs to the UPF0473 family
CEW82_RS14010	COG1193	negative regulation of DNA recombination
CEW82_RS14015	COG3118	belongs to the thioredoxin family
CEW82_RS14025	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
CEW82_RS14030	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
CEW82_RS14040	COG0517	IMP dehydrogenase activity
CEW82_RS14045	COG2171	N-acyltransferase activity
CEW82_RS14050	COG1473	amidohydrolase
CEW82_RS14065	COG0668	transmembrane transport
CEW82_RS14080	COG0789	Transcriptional regulator
CEW82_RS14085	COG1346	cytolysis
CEW82_RS14095	COG3279	Response regulator of the LytR AlgR family
CEW82_RS14100	COG3275	phosphorelay sensor kinase activity
CEW82_RS14105	COG0006	proline dipeptidase activity
CEW82_RS14110	COG1609	Transcriptional regulator
CEW82_RS14130	COG0217	transcriptional regulatory protein
CEW82_RS14140	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CEW82_RS14150	COG4537	Required for transformation and DNA binding
CEW82_RS14170	COG0827	DNA restriction-modification system
CEW82_RS14175	COG1113	amino acid transport
CEW82_RS14185	COG0737	Belongs to the 5'-nucleotidase family
CEW82_RS14190	COG4470	Protein conserved in bacteria
CEW82_RS14195	COG0647	UMP catabolic process
CEW82_RS14205	COG0586	Pfam SNARE associated Golgi protein
CEW82_RS14215	COG1098	S1 RNA binding domain
CEW82_RS14365	COG1234	tRNA 3'-trailer cleavage
CEW82_RS14370	COG1393	Belongs to the ArsC family
CEW82_RS14375	COG4862	establishment of competence for transformation
CEW82_RS14395	COG2357	RelA SpoT domain protein
CEW82_RS14400	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CEW82_RS14405	COG0564	pseudouridine synthase activity
CEW82_RS14410	COG3142	Participates in the control of copper homeostasis
CEW82_RS14415	COG2706	6-phosphogluconolactonase activity
CEW82_RS14430	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
CEW82_RS14445	COG1114	Component of the transport system for branched-chain amino acids
CEW82_RS14450	COG2910	NAD(P)H-binding
CEW82_RS14455	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
CEW82_RS14460	COG1674	ftsk spoiiie
CEW82_RS14480	COG2001	Belongs to the MraZ family
CEW82_RS14485	COG0275	rRNA processing
CEW82_RS14495	COG0768	penicillin binding
CEW82_RS14500	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CEW82_RS14505	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
CEW82_RS14510	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CEW82_RS14515	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
CEW82_RS14525	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CEW82_RS14530	COG1799	cell septum assembly
CEW82_RS14535	COG0762	integral membrane protein
CEW82_RS14545	COG3599	regulation of cell shape
CEW82_RS14550	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
CEW82_RS14565	COG3279	Response regulator of the LytR AlgR family
CEW82_RS14575	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
CEW82_RS14580	COG0494	nUDIX hydrolase
CEW82_RS14590	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CEW82_RS14595	COG1104	cysteine desulfurase activity
CEW82_RS14605	COG0482	sulfurtransferase activity
CEW82_RS14610	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CEW82_RS14615	COG0569	domain protein
CEW82_RS14645	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CEW82_RS14650	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CEW82_RS14655	COG3584	3D domain protein
CEW82_RS14655	COG1388	LysM domain
CEW82_RS14680	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
CEW82_RS14685	COG5503	Protein of unknown function (DUF1447)
CEW82_RS14695	COG0242	peptide deformylase activity
CEW82_RS14720	COG0039	L-malate dehydrogenase activity
CEW82_RS14725	COG4476	Belongs to the UPF0223 family
CEW82_RS14730	COG0483	inositol monophosphate 1-phosphatase activity
CEW82_RS14735	COG1217	gtp-binding protein TYPA
CEW82_RS14770	COG0772	Belongs to the SEDS family
CEW82_RS14775	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
CEW82_RS14785	COG4471	UPF0298 protein
CEW82_RS14790	COG0742	ribosomal rna small subunit methyltransferase
CEW82_RS14795	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
CEW82_RS14800	COG3480	Lon protease (S16) C-terminal proteolytic domain
CEW82_RS14805	COG1596	polysaccharide export
CEW82_RS14805	COG1555	photosystem II stabilization
CEW82_RS14810	COG2131	deaminase
CEW82_RS14815	COG0658	competence protein
CEW82_RS14815	COG2333	competence protein COMEC
CEW82_RS14820	COG1466	dna polymerase III delta subunit
CEW82_RS14825	COG0268	Binds directly to 16S ribosomal RNA
CEW82_RS14835	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
CEW82_RS14840	COG2814	Major facilitator Superfamily
CEW82_RS14860	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CEW82_RS14865	COG0544	peptidyl-prolyl cis-trans isomerase activity
CEW82_RS14870	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
CEW82_RS14875	COG0218	Necessary for normal cell division and for the maintenance of normal septation
CEW82_RS14895	COG0765	amino acid transport
CEW82_RS14900	COG1126	abc transporter atp-binding protein
CEW82_RS14915	COG0489	protein tyrosine kinase activity
CEW82_RS14920	COG4464	protein tyrosine phosphatase activity
CEW82_RS14925	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CEW82_RS14930	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CEW82_RS14935	COG0438	transferase activity, transferring glycosyl groups
CEW82_RS14935	COG0297	glycogen (starch) synthase activity
CEW82_RS14940	COG0438	transferase activity, transferring glycosyl groups
CEW82_RS14950	COG1215	transferase activity, transferring glycosyl groups
CEW82_RS14960	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
CEW82_RS14980	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CEW82_RS14990	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CEW82_RS14990	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CEW82_RS14990	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CEW82_RS14995	COG1105	Belongs to the carbohydrate kinase PfkB family
CEW82_RS15000	COG1349	DNA-binding transcription factor activity
CEW82_RS15005	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
CEW82_RS15020	COG1234	tRNA 3'-trailer cleavage
CEW82_RS15025	COG0300	oxidoreductase activity
CEW82_RS15030	COG5416	Lipopolysaccharide assembly protein A domain
CEW82_RS15035	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
CEW82_RS15035	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
CEW82_RS15040	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CEW82_RS15055	COG0393	Putative heavy-metal-binding
CEW82_RS15135	COG0463	Glycosyl transferase, family 2
CEW82_RS15150	COG3425	synthase
CEW82_RS15160	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CEW82_RS15165	COG4224	UPF0291 protein
CEW82_RS15170	COG3763	UPF0154 protein
CEW82_RS15175	COG0204	Acyl-transferase
CEW82_RS15180	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
CEW82_RS15185	COG2827	Endonuclease containing a URI domain
CEW82_RS15190	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CEW82_RS15200	COG0052	Belongs to the universal ribosomal protein uS2 family
CEW82_RS15205	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
CEW82_RS15210	COG0528	UMP kinase activity
CEW82_RS15215	COG0233	cytoplasmic translational termination
CEW82_RS15220	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CEW82_RS15225	COG4589	Belongs to the CDS family
CEW82_RS15230	COG0750	zinc metalloprotease
CEW82_RS15235	COG0442	prolyl-tRNA aminoacylation
CEW82_RS15240	COG2176	DNA-directed DNA polymerase activity
CEW82_RS15245	COG0779	Required for maturation of 30S ribosomal subunits
CEW82_RS15250	COG0195	Participates in both transcription termination and antitermination
CEW82_RS15255	COG2740	Nucleic-acid-binding protein implicated in transcription termination
CEW82_RS15265	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
CEW82_RS15270	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
CEW82_RS15285	COG0738	Major facilitator superfamily
CEW82_RS15290	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
CEW82_RS15300	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
CEW82_RS15305	COG0287	Prephenate dehydrogenase
CEW82_RS15310	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
CEW82_RS15315	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
CEW82_RS15320	COG0196	riboflavin kinase activity
CEW82_RS15325	COG3527	Alpha-acetolactate decarboxylase
CEW82_RS15330	COG1420	regulation of RNA biosynthetic process
CEW82_RS15335	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
CEW82_RS15340	COG0443	Heat shock 70 kDa protein
CEW82_RS15345	COG0484	heat shock protein binding
CEW82_RS15350	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CEW82_RS15360	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CEW82_RS15365	COG1696	Membrane protein involved in D-alanine export
CEW82_RS15370	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CEW82_RS15375	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
CEW82_RS15380	COG0481	GTPase activity
CEW82_RS15405	COG2094	Belongs to the DNA glycosylase MPG family
CEW82_RS15410	COG2264	protein methyltransferase activity
CEW82_RS15415	COG1385	rRNA (uridine-N3-)-methyltransferase activity
CEW82_RS15425	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CEW82_RS15430	COG1490	D-aminoacyl-tRNA deacylase activity
CEW82_RS15435	COG0546	phosphoglycolate phosphatase activity
CEW82_RS15440	COG3001	Fructosamine kinase
CEW82_RS15445	COG0860	N-Acetylmuramoyl-L-alanine amidase
CEW82_RS15445	COG4991	sh3 domain protein
CEW82_RS15445	COG3103	Sh3 type 3 domain protein
CEW82_RS15450	COG0124	histidyl-tRNA synthetase
CEW82_RS15455	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
CEW82_RS15460	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CEW82_RS15465	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CEW82_RS15480	COG1028	Short-chain dehydrogenase reductase Sdr
CEW82_RS15485	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
CEW82_RS15490	COG0828	Belongs to the bacterial ribosomal protein bS21 family
CEW82_RS15495	COG1610	YqeY-like protein
CEW82_RS15505	COG1702	phosphate starvation-inducible protein PhoH
CEW82_RS15510	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
CEW82_RS15515	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
CEW82_RS15520	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
CEW82_RS15525	COG1381	Involved in DNA repair and RecF pathway recombination
CEW82_RS15530	COG0752	glycyl-tRNA synthetase alpha subunit
CEW82_RS15535	COG0751	glycine-tRNA ligase activity
CEW82_RS15540	COG0358	DNA primase activity
CEW82_RS15545	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CEW82_RS15550	COG1725	Transcriptional regulator
CEW82_RS15555	COG1131	(ABC) transporter
CEW82_RS15580	COG1131	(ABC) transporter
CEW82_RS15590	COG4585	Histidine kinase
CEW82_RS15595	COG2197	response regulator
CEW82_RS15600	COG0446	pyridine nucleotide-disulphide oxidoreductase
CEW82_RS15605	COG0604	alcohol dehydrogenase
CEW82_RS15610	COG0583	DNA-binding transcription factor activity
CEW82_RS15645	COG1737	Transcriptional regulator
CEW82_RS15655	COG0546	phosphoglycolate phosphatase activity
CEW82_RS15690	COG0477	Major facilitator Superfamily
CEW82_RS15695	COG1733	regulation of RNA biosynthetic process
CEW82_RS15700	COG1125	glycine betaine transport
CEW82_RS15700	COG0517	IMP dehydrogenase activity
CEW82_RS15705	COG1174	glycine betaine transport
CEW82_RS15715	COG4221	oxidoreductase activity
CEW82_RS15720	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CEW82_RS15720	COG5549	protein import
CEW82_RS15735	COG0583	DNA-binding transcription factor activity
CEW82_RS15750	COG3052	prosthetic group binding
CEW82_RS15770	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CEW82_RS15770	COG0574	Belongs to the PEP-utilizing enzyme family
CEW82_RS15795	COG2315	Protein conserved in bacteria
CEW82_RS15805	COG2384	SAM-dependent methyltransferase
CEW82_RS15810	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
CEW82_RS15820	COG0542	response to heat
CEW82_RS15840	COG0587	DNA-directed DNA polymerase activity
CEW82_RS15845	COG0205	6-phosphofructokinase activity
CEW82_RS15860	COG2996	Protein conserved in bacteria
CEW82_RS15865	COG4974	Belongs to the 'phage' integrase family
CEW82_RS15875	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
CEW82_RS15880	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
CEW82_RS15885	COG1187	pseudouridine synthase activity
CEW82_RS15890	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
CEW82_RS15905	COG0514	ATP-dependent DNA helicase (RecQ)
CEW82_RS15915	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
CEW82_RS15920	COG0539	negative regulation of cytoplasmic translation
CEW82_RS15925	COG1160	GTP binding
CEW82_RS15940	COG0457	Tetratricopeptide repeat
CEW82_RS15945	COG0561	phosphatase activity
CEW82_RS15950	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
CEW82_RS15955	COG0617	tRNA 3'-terminal CCA addition
CEW82_RS15965	COG0488	(ABC) transporter
CEW82_RS15970	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
CEW82_RS15975	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
CEW82_RS15980	COG1307	EDD domain protein, DegV family
CEW82_RS15985	COG2755	lipolytic protein G-D-S-L family
CEW82_RS15990	COG4698	Protein conserved in bacteria
CEW82_RS15995	COG4479	Belongs to the UPF0346 family
CEW82_RS16000	COG3409	Peptidoglycan-binding domain 1 protein
CEW82_RS16000	COG0793	Belongs to the peptidase S41A family
CEW82_RS16010	COG0583	DNA-binding transcription factor activity
CEW82_RS16015	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
CEW82_RS16020	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
CEW82_RS16025	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CEW82_RS16030	COG0758	DNA mediated transformation
CEW82_RS16035	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CEW82_RS16040	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
CEW82_RS16045	COG4974	Belongs to the 'phage' integrase family
CEW82_RS16050	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
CEW82_RS16055	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
CEW82_RS16065	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
CEW82_RS16070	COG0187	DNA topoisomerase II activity
CEW82_RS16080	COG0583	DNA-binding transcription factor activity
CEW82_RS16085	COG1227	inorganic diphosphatase activity
CEW82_RS16090	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CEW82_RS16135	COG1309	transcriptional regulator
CEW82_RS16145	COG1131	(ABC) transporter
CEW82_RS16150	COG0783	Belongs to the Dps family
CEW82_RS16180	COG0577	efflux transmembrane transporter activity
CEW82_RS16185	COG1136	(ABC) transporter
CEW82_RS16235	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
CEW82_RS16260	COG1263	PTS System
CEW82_RS16260	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CEW82_RS16260	COG2190	(PTS) system
CEW82_RS16265	COG1349	DNA-binding transcription factor activity
CEW82_RS16270	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CEW82_RS16270	COG1263	PTS System
CEW82_RS16270	COG2190	(PTS) system
CEW82_RS16285	COG0698	ribose 5-phosphate isomerase
CEW82_RS16310	COG1192	Involved in chromosome partitioning
CEW82_RS16340	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CEW82_RS16345	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CEW82_RS16350	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CEW82_RS16435	COG2826	transposase and inactivated derivatives, IS30 family
CEW82_RS16445	COG3158	transport of potassium into the cell
CEW82_RS16450	COG1846	Transcriptional regulator