locus-tag	class	description
BL295_RS00005	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
BL295_RS00015	COG0583	DNA-binding transcription factor activity
BL295_RS00035	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BL295_RS00045	COG0242	peptide deformylase activity
BL295_RS00055	COG1328	CTP reductase activity
BL295_RS00105	COG2270	Major facilitator Superfamily
BL295_RS00120	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
BL295_RS00130	COG0561	phosphatase activity
BL295_RS00135	COG0488	(ABC) transporter
BL295_RS00160	COG0640	Transcriptional regulator
BL295_RS00170	COG1511	domain protein
BL295_RS00170	COG1511	domain protein
BL295_RS00195	COG1132	(ABC) transporter
BL295_RS00200	COG1132	(ABC) transporter
BL295_RS00205	COG0667	Aldo Keto reductase
BL295_RS00215	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
BL295_RS00230	COG1011	Hydrolase
BL295_RS00235	COG0110	maltose O-acetyltransferase activity
BL295_RS00240	COG0589	response to stress
BL295_RS00250	COG1028	Short-chain dehydrogenase reductase Sdr
BL295_RS00255	COG1063	alcohol dehydrogenase
BL295_RS00265	COG0583	DNA-binding transcription factor activity
BL295_RS00290	COG0456	acetyltransferase
BL295_RS00310	COG0110	maltose O-acetyltransferase activity
BL295_RS00315	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
BL295_RS00335	COG0789	Transcriptional regulator
BL295_RS00350	COG4221	oxidoreductase activity
BL295_RS00360	COG4152	abc transporter atp-binding protein
BL295_RS00375	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BL295_RS00390	COG0438	transferase activity, transferring glycosyl groups
BL295_RS00400	COG0583	DNA-binding transcription factor activity
BL295_RS00405	COG2855	membrane
BL295_RS00410	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BL295_RS00420	COG2814	Major facilitator Superfamily
BL295_RS00430	COG2814	Major facilitator Superfamily
BL295_RS00475	COG1136	(ABC) transporter
BL295_RS00480	COG0577	efflux transmembrane transporter activity
BL295_RS00495	COG0789	Transcriptional regulator
BL295_RS00495	COG4978	Transcriptional regulator
BL295_RS00500	COG1811	Na channel or pump
BL295_RS00520	COG4990	cell redox homeostasis
BL295_RS00535	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
BL295_RS00540	COG4720	Psort location CytoplasmicMembrane, score
BL295_RS00585	COG0531	amino acid
BL295_RS00590	COG0710	3-dehydroquinate dehydratase activity
BL295_RS00610	COG0716	FMN binding
BL295_RS00635	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
BL295_RS00640	COG0561	phosphatase activity
BL295_RS00655	COG1216	Glycosyl transferase, family 2
BL295_RS00660	COG2188	Transcriptional regulator
BL295_RS00665	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BL295_RS00670	COG1447	Phosphotransferase system cellobiose-specific component IIA
BL295_RS00675	COG2723	6-phospho-beta-galactosidase activity
BL295_RS00680	COG2723	6-phospho-beta-galactosidase activity
BL295_RS00685	COG3048	D-serine ammonia-lyase activity
BL295_RS00690	COG1131	(ABC) transporter
BL295_RS00700	COG1309	transcriptional regulator
BL295_RS00705	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
BL295_RS00710	COG1827	regulation of RNA biosynthetic process
BL295_RS00740	COG0494	nUDIX hydrolase
BL295_RS00745	COG0110	maltose O-acetyltransferase activity
BL295_RS00755	COG0561	phosphatase activity
BL295_RS00765	COG0366	Alpha amylase catalytic
BL295_RS00785	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
BL295_RS00805	COG2246	polysaccharide biosynthetic process
BL295_RS00815	COG0589	response to stress
BL295_RS00825	COG1131	(ABC) transporter
BL295_RS00830	COG1725	Transcriptional regulator
BL295_RS00845	COG1136	(ABC) transporter
BL295_RS00865	COG2365	Tyrosine phosphatase family
BL295_RS00870	COG0095	Lipoate-protein ligase
BL295_RS00875	COG3976	FMN-binding domain protein
BL295_RS00875	COG1053	succinate dehydrogenase
BL295_RS00875	COG0431	NADPH-dependent FMN reductase
BL295_RS00880	COG3976	FMN-binding domain protein
BL295_RS00880	COG0431	NADPH-dependent FMN reductase
BL295_RS00880	COG1053	succinate dehydrogenase
BL295_RS00890	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
BL295_RS00895	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
BL295_RS00900	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BL295_RS00905	COG0047	phosphoribosylformylglycinamidine synthase activity
BL295_RS00920	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
BL295_RS00925	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
BL295_RS00930	COG0138	bifunctional purine biosynthesis protein purh
BL295_RS00935	COG0151	Belongs to the GarS family
BL295_RS00965	COG2252	PERMEase
BL295_RS00970	COG2233	PERMEase
BL295_RS00975	COG2508	Transcriptional regulator
BL295_RS00980	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
BL295_RS00985	COG0540	Belongs to the ATCase OTCase family
BL295_RS00990	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
BL295_RS00995	COG0505	Belongs to the CarA family
BL295_RS01000	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
BL295_RS01005	COG0167	dihydroorotate dehydrogenase activity
BL295_RS01010	COG0284	orotidine-5'-phosphate decarboxylase activity
BL295_RS01015	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
BL295_RS01025	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
BL295_RS01030	COG1074	ATP-dependent DNA helicase activity
BL295_RS01040	COG0702	epimerase
BL295_RS01045	COG0583	DNA-binding transcription factor activity
BL295_RS01055	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BL295_RS01060	COG0436	Aminotransferase
BL295_RS01065	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BL295_RS01075	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
BL295_RS01090	COG0789	Transcriptional regulator
BL295_RS01095	COG2814	Major facilitator Superfamily
BL295_RS01100	COG0025	NhaP-type Na H and K H
BL295_RS01105	COG1780	Probably involved in ribonucleotide reductase function
BL295_RS01110	COG1253	flavin adenine dinucleotide binding
BL295_RS01140	COG1418	mRNA catabolic process
BL295_RS01150	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
BL295_RS01155	COG2188	Transcriptional regulator
BL295_RS01165	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
BL295_RS01180	COG1396	sequence-specific DNA binding
BL295_RS01185	COG0564	pseudouridine synthase activity
BL295_RS01190	COG0589	response to stress
BL295_RS01195	COG1705	Flagellar rod assembly protein muramidase FlgJ
BL295_RS01200	COG0095	Lipoate-protein ligase
BL295_RS01230	COG0626	cystathionine gamma-synthase activity
BL295_RS01235	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BL295_RS01240	COG1073	alpha beta
BL295_RS01250	COG0028	Belongs to the TPP enzyme family
BL295_RS01300	COG1725	Transcriptional regulator
BL295_RS01305	COG1131	(ABC) transporter
BL295_RS01315	COG1335	isochorismatase
BL295_RS01320	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
BL295_RS01325	COG0025	NhaP-type Na H and K H
BL295_RS01330	COG0673	inositol 2-dehydrogenase activity
BL295_RS01335	COG0673	inositol 2-dehydrogenase activity
BL295_RS01345	COG1609	Transcriptional regulator
BL295_RS01355	COG0328	RNA-DNA hybrid ribonuclease activity
BL295_RS01365	COG0778	Nitroreductase
BL295_RS01370	COG2326	polyphosphate kinase activity
BL295_RS01375	COG4932	domain protein
BL295_RS01385	COG0492	ferredoxin-NADP+ reductase activity
BL295_RS01395	COG0584	glycerophosphoryl diester phosphodiesterase
BL295_RS01400	COG1368	sulfuric ester hydrolase activity
BL295_RS01420	COG3548	integral membrane protein
BL295_RS01435	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
BL295_RS01445	COG0300	oxidoreductase activity
BL295_RS01450	COG0789	Transcriptional regulator
BL295_RS01470	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
BL295_RS01475	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
BL295_RS01480	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
BL295_RS01485	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
BL295_RS01490	COG0131	Imidazoleglycerol-phosphate dehydratase
BL295_RS01495	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
BL295_RS01500	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
BL295_RS01505	COG0107	imidazoleglycerol-phosphate synthase activity
BL295_RS01510	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
BL295_RS01515	COG0140	phosphoribosyl-ATP diphosphatase activity
BL295_RS01520	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BL295_RS01525	COG0110	maltose O-acetyltransferase activity
BL295_RS01530	COG0861	Integral membrane protein TerC family
BL295_RS01535	COG2084	Dehydrogenase
BL295_RS01545	COG0446	pyridine nucleotide-disulphide oxidoreductase
BL295_RS01555	COG4120	Belongs to the binding-protein-dependent transport system permease family
BL295_RS01570	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
BL295_RS01575	COG2873	o-acetylhomoserine
BL295_RS01585	COG1307	EDD domain protein, DegV family
BL295_RS01590	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
BL295_RS01595	COG2190	(PTS) system
BL295_RS01595	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BL295_RS01595	COG1263	PTS System
BL295_RS01620	COG0488	(ABC) transporter
BL295_RS01640	COG1522	sequence-specific DNA binding
BL295_RS01645	COG0791	NLP P60 protein
BL295_RS01660	COG0477	Major facilitator Superfamily
BL295_RS01685	COG3830	Belongs to the UPF0237 family
BL295_RS01690	COG2848	UPF0210 protein
BL295_RS01695	COG0745	RESPONSE REGULATOR receiver
BL295_RS01700	COG3850	Histidine kinase
BL295_RS01700	COG5002	protein histidine kinase activity
BL295_RS01705	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
BL295_RS01710	COG4975	Glucose uptake
BL295_RS01715	COG0166	Belongs to the GPI family
BL295_RS01735	COG1132	(ABC) transporter
BL295_RS01770	COG4974	Belongs to the 'phage' integrase family
BL295_RS01835	COG4695	Portal protein
BL295_RS01930	COG1396	sequence-specific DNA binding
BL295_RS02095	COG3953	SLT domain
BL295_RS02095	COG5280	Phage tail tape measure protein TP901
BL295_RS02140	COG0726	polysaccharide deacetylase
BL295_RS02155	COG1132	(ABC) transporter
BL295_RS02170	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BL295_RS02180	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BL295_RS02185	COG1482	cell wall glycoprotein biosynthetic process
BL295_RS02190	COG3442	glutamine amidotransferase
BL295_RS02195	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
BL295_RS02200	COG1435	thymidine kinase activity
BL295_RS02205	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
BL295_RS02210	COG2890	protein-(glutamine-N5) methyltransferase activity
BL295_RS02215	COG0009	L-threonylcarbamoyladenylate synthase
BL295_RS02220	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
BL295_RS02225	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
BL295_RS02235	COG2233	PERMEase
BL295_RS02240	COG0356	it plays a direct role in the translocation of protons across the membrane
BL295_RS02245	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
BL295_RS02250	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
BL295_RS02255	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
BL295_RS02260	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
BL295_RS02265	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
BL295_RS02270	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
BL295_RS02275	COG0355	proton-transporting ATP synthase activity, rotational mechanism
BL295_RS02280	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
BL295_RS02290	COG1077	Cell shape determining protein MreB Mrl
BL295_RS02295	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
BL295_RS02305	COG0772	Belongs to the SEDS family
BL295_RS02310	COG0509	glycine decarboxylation via glycine cleavage system
BL295_RS02315	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
BL295_RS02320	COG2011	ABC-type metal ion transport system permease component
BL295_RS02325	COG1464	Belongs to the NlpA lipoprotein family
BL295_RS02345	COG1181	Belongs to the D-alanine--D-alanine ligase family
BL295_RS02365	COG0589	response to stress
BL295_RS02380	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
BL295_RS02385	COG0189	ligase activity
BL295_RS02385	COG2918	glutathione biosynthetic process
BL295_RS02390	COG0640	Transcriptional regulator
BL295_RS02405	COG4493	Belongs to the UPF0637 family
BL295_RS02410	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
BL295_RS02415	COG1956	GAF domain-containing protein
BL295_RS02420	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
BL295_RS02430	COG1104	cysteine desulfurase activity
BL295_RS02435	COG0301	tRNA thio-modification
BL295_RS02440	COG1181	Belongs to the D-alanine--D-alanine ligase family
BL295_RS02440	COG2918	glutathione biosynthetic process
BL295_RS02450	COG0525	valine-tRNA ligase activity
BL295_RS02455	COG0285	dihydrofolate synthase activity
BL295_RS02460	COG2003	Belongs to the UPF0758 family
BL295_RS02465	COG1077	Cell shape determining protein MreB Mrl
BL295_RS02470	COG1792	Involved in formation and maintenance of cell shape
BL295_RS02480	COG0850	regulation of cytokinetic process
BL295_RS02485	COG2894	cell division
BL295_RS02490	COG0765	amino acid transport
BL295_RS02495	COG1126	abc transporter atp-binding protein
BL295_RS02500	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BL295_RS02510	COG0527	aspartate kinase activity
BL295_RS02515	COG0612	Peptidase, M16
BL295_RS02520	COG0612	Peptidase, M16
BL295_RS02525	COG1426	Protein conserved in bacteria
BL295_RS02530	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
BL295_RS02535	COG1058	Belongs to the CinA family
BL295_RS02535	COG1546	Belongs to the CinA family
BL295_RS02540	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
BL295_RS02545	COG1418	mRNA catabolic process
BL295_RS02550	COG1692	metallophosphoesterase
BL295_RS02555	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
BL295_RS02560	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
BL295_RS02600	COG0632	four-way junction helicase activity
BL295_RS02605	COG2255	four-way junction helicase activity
BL295_RS02610	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
BL295_RS02615	COG0343	queuine tRNA-ribosyltransferase activity
BL295_RS02620	COG1862	Preprotein translocase
BL295_RS02625	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BL295_RS02630	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
BL295_RS02635	COG0513	Belongs to the DEAD box helicase family
BL295_RS02640	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BL295_RS02645	COG4472	Bacterial protein of unknown function (DUF965)
BL295_RS02650	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
BL295_RS02655	COG3906	Belongs to the UPF0473 family
BL295_RS02665	COG1193	negative regulation of DNA recombination
BL295_RS02670	COG3118	belongs to the thioredoxin family
BL295_RS02675	COG1719	4-vinyl reductase, 4VR
BL295_RS02680	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
BL295_RS02685	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
BL295_RS02695	COG0517	IMP dehydrogenase activity
BL295_RS02700	COG2171	N-acyltransferase activity
BL295_RS02705	COG1473	amidohydrolase
BL295_RS02710	COG0668	transmembrane transport
BL295_RS02725	COG0789	Transcriptional regulator
BL295_RS02730	COG0006	proline dipeptidase activity
BL295_RS02735	COG1609	Transcriptional regulator
BL295_RS02750	COG0217	transcriptional regulatory protein
BL295_RS02760	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
BL295_RS02790	COG0827	DNA restriction-modification system
BL295_RS02795	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
BL295_RS02800	COG1113	amino acid transport
BL295_RS02815	COG0737	Belongs to the 5'-nucleotidase family
BL295_RS02820	COG4470	Protein conserved in bacteria
BL295_RS02825	COG0647	UMP catabolic process
BL295_RS02835	COG0586	Pfam SNARE associated Golgi protein
BL295_RS02845	COG1098	S1 RNA binding domain
BL295_RS02985	COG1234	tRNA 3'-trailer cleavage
BL295_RS02990	COG1393	Belongs to the ArsC family
BL295_RS02995	COG4862	establishment of competence for transformation
BL295_RS03005	COG1164	Oligoendopeptidase f
BL295_RS03015	COG2357	RelA SpoT domain protein
BL295_RS03020	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
BL295_RS03025	COG0564	pseudouridine synthase activity
BL295_RS03030	COG3142	Participates in the control of copper homeostasis
BL295_RS03035	COG2706	6-phosphogluconolactonase activity
BL295_RS03045	COG0628	permease
BL295_RS03050	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
BL295_RS03065	COG1114	Component of the transport system for branched-chain amino acids
BL295_RS03075	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
BL295_RS03080	COG1674	ftsk spoiiie
BL295_RS03110	COG2001	Belongs to the MraZ family
BL295_RS03115	COG0275	rRNA processing
BL295_RS03125	COG0768	penicillin binding
BL295_RS03130	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BL295_RS03135	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
BL295_RS03140	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
BL295_RS03145	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
BL295_RS03160	COG1799	cell septum assembly
BL295_RS03165	COG0762	integral membrane protein
BL295_RS03175	COG3599	regulation of cell shape
BL295_RS03180	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
BL295_RS03185	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
BL295_RS03190	COG0494	nUDIX hydrolase
BL295_RS03200	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
BL295_RS03205	COG1104	cysteine desulfurase activity
BL295_RS03215	COG0482	sulfurtransferase activity
BL295_RS03220	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BL295_RS03225	COG0569	domain protein
BL295_RS03260	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
BL295_RS03265	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
BL295_RS03270	COG3584	3D domain protein
BL295_RS03270	COG1388	LysM domain
BL295_RS03280	COG1597	lipid kinase activity
BL295_RS03285	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
BL295_RS03290	COG5503	Protein of unknown function (DUF1447)
BL295_RS03300	COG0242	peptide deformylase activity
BL295_RS03325	COG0039	L-malate dehydrogenase activity
BL295_RS03330	COG4476	Belongs to the UPF0223 family
BL295_RS03340	COG1217	gtp-binding protein TYPA
BL295_RS03375	COG0772	Belongs to the SEDS family
BL295_RS03380	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
BL295_RS03385	COG4471	UPF0298 protein
BL295_RS03390	COG0742	ribosomal rna small subunit methyltransferase
BL295_RS03395	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
BL295_RS03400	COG3480	Lon protease (S16) C-terminal proteolytic domain
BL295_RS03405	COG1555	photosystem II stabilization
BL295_RS03405	COG1596	polysaccharide export
BL295_RS03410	COG2131	deaminase
BL295_RS03415	COG2333	competence protein COMEC
BL295_RS03415	COG0658	competence protein
BL295_RS03420	COG1466	dna polymerase III delta subunit
BL295_RS03425	COG0268	Binds directly to 16S ribosomal RNA
BL295_RS03430	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
BL295_RS03455	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
BL295_RS03460	COG0544	peptidyl-prolyl cis-trans isomerase activity
BL295_RS03465	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
BL295_RS03470	COG0218	Necessary for normal cell division and for the maintenance of normal septation
BL295_RS03485	COG0765	amino acid transport
BL295_RS03490	COG1126	abc transporter atp-binding protein
BL295_RS03495	COG0322	excinuclease ABC activity
BL295_RS03505	COG0489	protein tyrosine kinase activity
BL295_RS03515	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BL295_RS03550	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
BL295_RS03555	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BL295_RS03555	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BL295_RS03555	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BL295_RS03560	COG1105	Belongs to the carbohydrate kinase PfkB family
BL295_RS03565	COG1349	DNA-binding transcription factor activity
BL295_RS03570	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
BL295_RS03580	COG1234	tRNA 3'-trailer cleavage
BL295_RS03585	COG0300	oxidoreductase activity
BL295_RS03590	COG5416	Lipopolysaccharide assembly protein A domain
BL295_RS03595	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
BL295_RS03595	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
BL295_RS03600	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BL295_RS03615	COG0393	Putative heavy-metal-binding
BL295_RS03635	COG0772	Belongs to the SEDS family
BL295_RS03645	COG1116	anion transmembrane transporter activity
BL295_RS03650	COG1316	TRANSCRIPTIONal
BL295_RS03660	COG0463	Glycosyl transferase, family 2
BL295_RS03675	COG3425	synthase
BL295_RS03690	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
BL295_RS03695	COG4224	UPF0291 protein
BL295_RS03700	COG3763	UPF0154 protein
BL295_RS03705	COG0204	Acyl-transferase
BL295_RS03710	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
BL295_RS03715	COG2827	Endonuclease containing a URI domain
BL295_RS03720	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BL295_RS03730	COG0052	Belongs to the universal ribosomal protein uS2 family
BL295_RS03735	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
BL295_RS03740	COG0528	UMP kinase activity
BL295_RS03745	COG0233	cytoplasmic translational termination
BL295_RS03750	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
BL295_RS03755	COG4589	Belongs to the CDS family
BL295_RS03760	COG0750	zinc metalloprotease
BL295_RS03765	COG0442	prolyl-tRNA aminoacylation
BL295_RS03770	COG2176	DNA-directed DNA polymerase activity
BL295_RS03775	COG0779	Required for maturation of 30S ribosomal subunits
BL295_RS03780	COG0195	Participates in both transcription termination and antitermination
BL295_RS03785	COG2740	Nucleic-acid-binding protein implicated in transcription termination
BL295_RS03795	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
BL295_RS03800	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
BL295_RS03805	COG0738	Major facilitator superfamily
BL295_RS03810	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
BL295_RS03825	COG0287	Prephenate dehydrogenase
BL295_RS03830	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
BL295_RS03835	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
BL295_RS03840	COG0196	riboflavin kinase activity
BL295_RS03845	COG3527	Alpha-acetolactate decarboxylase
BL295_RS03850	COG1420	regulation of RNA biosynthetic process
BL295_RS03855	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
BL295_RS03860	COG0443	Heat shock 70 kDa protein
BL295_RS03865	COG0484	heat shock protein binding
BL295_RS03870	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BL295_RS03880	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BL295_RS03885	COG1696	Membrane protein involved in D-alanine export
BL295_RS03890	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BL295_RS03895	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
BL295_RS03900	COG0481	GTPase activity
BL295_RS03905	COG0582	viral genome integration into host DNA
BL295_RS03930	COG2094	Belongs to the DNA glycosylase MPG family
BL295_RS03935	COG2264	protein methyltransferase activity
BL295_RS03940	COG1385	rRNA (uridine-N3-)-methyltransferase activity
BL295_RS03950	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BL295_RS03955	COG1490	D-aminoacyl-tRNA deacylase activity
BL295_RS03960	COG0546	phosphoglycolate phosphatase activity
BL295_RS03965	COG3001	Fructosamine kinase
BL295_RS03970	COG4991	sh3 domain protein
BL295_RS03970	COG0860	N-Acetylmuramoyl-L-alanine amidase
BL295_RS03970	COG3103	Sh3 type 3 domain protein
BL295_RS03975	COG0124	histidyl-tRNA synthetase
BL295_RS03980	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
BL295_RS03990	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BL295_RS04000	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
BL295_RS04010	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
BL295_RS04015	COG0828	Belongs to the bacterial ribosomal protein bS21 family
BL295_RS04020	COG1610	YqeY-like protein
BL295_RS04025	COG1702	phosphate starvation-inducible protein PhoH
BL295_RS04030	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
BL295_RS04035	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
BL295_RS04040	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
BL295_RS04045	COG1381	Involved in DNA repair and RecF pathway recombination
BL295_RS04050	COG0752	glycyl-tRNA synthetase alpha subunit
BL295_RS04055	COG0751	glycine-tRNA ligase activity
BL295_RS04060	COG0358	DNA primase activity
BL295_RS04065	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BL295_RS04075	COG1725	Transcriptional regulator
BL295_RS04080	COG1131	(ABC) transporter
BL295_RS04100	COG1131	(ABC) transporter
BL295_RS04125	COG0519	Catalyzes the synthesis of GMP from XMP
BL295_RS04140	COG4585	Histidine kinase
BL295_RS04145	COG2197	response regulator
BL295_RS04150	COG0446	pyridine nucleotide-disulphide oxidoreductase
BL295_RS04160	COG0604	alcohol dehydrogenase
BL295_RS04165	COG0583	DNA-binding transcription factor activity
BL295_RS04195	COG0546	phosphoglycolate phosphatase activity
BL295_RS04240	COG1393	Belongs to the ArsC family
BL295_RS04250	COG1349	DNA-binding transcription factor activity
BL295_RS04260	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BL295_RS04270	COG0477	Major facilitator Superfamily
BL295_RS04280	COG2217	Heavy metal translocating P-type atpase
BL295_RS04300	COG1846	Transcriptional regulator
BL295_RS04310	COG0574	Belongs to the PEP-utilizing enzyme family
BL295_RS04310	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BL295_RS04335	COG2384	SAM-dependent methyltransferase
BL295_RS04340	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
BL295_RS04350	COG0542	response to heat
BL295_RS04360	COG0587	DNA-directed DNA polymerase activity
BL295_RS04365	COG0205	6-phosphofructokinase activity
BL295_RS04380	COG2996	Protein conserved in bacteria
BL295_RS04385	COG4974	Belongs to the 'phage' integrase family
BL295_RS04395	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
BL295_RS04400	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
BL295_RS04405	COG1187	pseudouridine synthase activity
BL295_RS04420	COG0514	ATP-dependent DNA helicase (RecQ)
BL295_RS04430	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
BL295_RS04435	COG0539	negative regulation of cytoplasmic translation
BL295_RS04440	COG1160	GTP binding
BL295_RS04450	COG0457	Tetratricopeptide repeat
BL295_RS04455	COG0561	phosphatase activity
BL295_RS04460	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
BL295_RS04465	COG0617	tRNA 3'-terminal CCA addition
BL295_RS04475	COG0488	(ABC) transporter
BL295_RS04480	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
BL295_RS04485	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
BL295_RS04490	COG1307	EDD domain protein, DegV family
BL295_RS04495	COG2755	lipolytic protein G-D-S-L family
BL295_RS04500	COG4698	Protein conserved in bacteria
BL295_RS04505	COG4479	Belongs to the UPF0346 family
BL295_RS04510	COG0793	Belongs to the peptidase S41A family
BL295_RS04510	COG3409	Peptidoglycan-binding domain 1 protein
BL295_RS04515	COG2814	Major facilitator Superfamily
BL295_RS04535	COG0583	DNA-binding transcription factor activity
BL295_RS04540	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
BL295_RS04550	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
BL295_RS04555	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
BL295_RS04560	COG0758	DNA mediated transformation
BL295_RS04565	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BL295_RS04570	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
BL295_RS04575	COG4974	Belongs to the 'phage' integrase family
BL295_RS04580	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
BL295_RS04585	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
BL295_RS04595	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
BL295_RS04600	COG0187	DNA topoisomerase II activity
BL295_RS04610	COG0583	DNA-binding transcription factor activity
BL295_RS04615	COG1227	inorganic diphosphatase activity
BL295_RS04620	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BL295_RS04665	COG1846	Transcriptional regulator
BL295_RS04680	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
BL295_RS04690	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
BL295_RS04700	COG1620	l-lactate permease
BL295_RS04715	COG1113	amino acid transport
BL295_RS04775	COG1307	EDD domain protein, DegV family
BL295_RS04785	COG1293	RNA-binding protein homologous to eukaryotic snRNP
BL295_RS04790	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
BL295_RS04795	COG1131	(ABC) transporter
BL295_RS04820	COG5646	InterPro IPR014922
BL295_RS04830	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
BL295_RS04835	COG0505	Belongs to the CarA family
BL295_RS04840	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
BL295_RS04845	COG0564	pseudouridine synthase activity
BL295_RS04850	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
BL295_RS04855	COG2759	Belongs to the formate--tetrahydrofolate ligase family
BL295_RS04870	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BL295_RS04895	COG1619	proteins homologs of microcin C7 resistance protein MccF
BL295_RS04915	COG1216	Glycosyl transferase, family 2
BL295_RS04925	COG1073	alpha beta
BL295_RS04930	COG0477	Major facilitator Superfamily
BL295_RS04940	COG0116	Belongs to the methyltransferase superfamily
BL295_RS04950	COG3599	regulation of cell shape
BL295_RS04955	COG4474	Belongs to the UPF0398 family
BL295_RS04960	COG3331	DNA recombination
BL295_RS04975	COG1840	ABC-type Fe3 transport system, periplasmic component
BL295_RS04980	COG1177	transmembrane transport
BL295_RS04990	COG1464	Belongs to the NlpA lipoprotein family
BL295_RS04995	COG2011	ABC-type metal ion transport system permease component
BL295_RS05000	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
BL295_RS05015	COG0017	Asparaginyl-tRNA synthetase
BL295_RS05030	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
BL295_RS05030	COG1199	ATP-dependent helicase activity
BL295_RS05050	COG1304	FMN binding
BL295_RS05055	COG2017	converts alpha-aldose to the beta-anomer
BL295_RS05075	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
BL295_RS05075	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
BL295_RS05080	COG0561	phosphatase activity
BL295_RS05085	COG0531	amino acid
BL295_RS05125	COG1942	4-Oxalocrotonate Tautomerase
BL295_RS05140	COG3237	CsbD-like
BL295_RS05145	COG2261	transglycosylase associated protein
BL295_RS05155	COG1597	lipid kinase activity
BL295_RS05160	COG3152	Membrane
BL295_RS05170	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
BL295_RS05180	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
BL295_RS05185	COG3397	chitin binding
BL295_RS05200	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
BL295_RS05220	COG0477	Major facilitator Superfamily
BL295_RS05230	COG1162	GTPase activity
BL295_RS05235	COG1607	acyl-coa hydrolase
BL295_RS05240	COG0583	DNA-binding transcription factor activity
BL295_RS05245	COG1811	Na channel or pump
BL295_RS05255	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
BL295_RS05270	COG0439	Biotin carboxylase
BL295_RS05285	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BL295_RS05290	COG1028	Short-chain dehydrogenase reductase Sdr
BL295_RS05295	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
BL295_RS05300	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BL295_RS05305	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BL295_RS05310	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
BL295_RS05320	COG0300	oxidoreductase activity
BL295_RS05330	COG1063	alcohol dehydrogenase
BL295_RS05335	COG1473	amidohydrolase
BL295_RS05345	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BL295_RS05360	COG0159	tryptophan synthase activity
BL295_RS05365	COG0133	tryptophan synthase activity
BL295_RS05370	COG0135	phosphoribosylanthranilate isomerase activity
BL295_RS05375	COG0134	indole-3-glycerol-phosphate synthase activity
BL295_RS05380	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
BL295_RS05385	COG0512	Glutamine amidotransferase of anthranilate synthase
BL295_RS05385	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
BL295_RS05400	COG1131	(ABC) transporter
BL295_RS05420	COG0335	large ribosomal subunit rRNA binding
BL295_RS05425	COG0336	Belongs to the RNA methyltransferase TrmD family
BL295_RS05430	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
BL295_RS05435	COG1837	Belongs to the UPF0109 family
BL295_RS05440	COG0228	four-way junction DNA binding
BL295_RS05445	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
BL295_RS05450	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
BL295_RS05455	COG0552	protein localization to endoplasmic reticulum
BL295_RS05460	COG1196	nuclear chromosome segregation
BL295_RS05465	COG0571	ribonuclease III activity
BL295_RS05470	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BL295_RS05475	COG0416	fatty acid biosynthetic process
BL295_RS05480	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
BL295_RS05485	COG1461	Dihydroxyacetone kinase
BL295_RS05490	COG1302	Protein conserved in bacteria
BL295_RS05495	COG0227	Belongs to the bacterial ribosomal protein bL28 family
BL295_RS05500	COG1564	THIamine pyrophosphokinase
BL295_RS05505	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
BL295_RS05510	COG1162	GTPase activity
BL295_RS05515	COG0515	serine threonine protein kinase
BL295_RS05515	COG2815	serine threonine protein kinase
BL295_RS05520	COG0631	protein serine/threonine phosphatase activity
BL295_RS05525	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BL295_RS05525	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
BL295_RS05530	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
BL295_RS05535	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
BL295_RS05540	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BL295_RS05545	COG1758	RNA polymerase activity
BL295_RS05550	COG0194	GDP metabolic process
BL295_RS05565	COG1732	Glycine betaine
BL295_RS05580	COG0497	DNA recombination
BL295_RS05585	COG1438	arginine binding
BL295_RS05590	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
BL295_RS05595	COG0142	geranyltranstransferase activity
BL295_RS05600	COG1722	exodeoxyribonuclease VII activity
BL295_RS05605	COG1570	exodeoxyribonuclease VII activity
BL295_RS05610	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
BL295_RS05615	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BL295_RS05620	COG1302	Protein conserved in bacteria
BL295_RS05625	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
BL295_RS05630	COG0006	proline dipeptidase activity
BL295_RS05635	COG0211	Belongs to the bacterial ribosomal protein bL27 family
BL295_RS05645	COG0261	This protein binds to 23S rRNA in the presence of protein L20
BL295_RS05690	COG0789	Transcriptional regulator
BL295_RS05695	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
BL295_RS05700	COG0584	glycerophosphoryl diester phosphodiesterase
BL295_RS05720	COG1940	carbohydrate kinase activity
BL295_RS05730	COG0705	Rhomboid family
BL295_RS05730	COG0457	Tetratricopeptide repeat
BL295_RS05735	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
BL295_RS05740	COG0267	Belongs to the bacterial ribosomal protein bL33 family
BL295_RS05745	COG0768	penicillin binding
BL295_RS05755	COG4841	protein insertion into membrane
BL295_RS05770	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BL295_RS05775	COG0572	uridine kinase
BL295_RS05780	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
BL295_RS05785	COG0072	phenylalanine-tRNA ligase activity
BL295_RS05785	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BL295_RS05790	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
BL295_RS05795	COG1733	regulation of RNA biosynthetic process
BL295_RS05805	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BL295_RS05810	COG1254	Belongs to the acylphosphatase family
BL295_RS05815	COG0706	membrane insertase activity
BL295_RS05830	COG0419	ATPase involved in DNA repair
BL295_RS05840	COG5002	protein histidine kinase activity
BL295_RS05845	COG0745	RESPONSE REGULATOR receiver
BL295_RS05850	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
BL295_RS05855	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
BL295_RS05870	COG0333	Belongs to the bacterial ribosomal protein bL32 family
BL295_RS05880	COG1323	Belongs to the UPF0348 family
BL295_RS05885	COG2226	methyltransferase
BL295_RS05890	COG0799	negative regulation of ribosome biogenesis
BL295_RS05895	COG1713	HD superfamily hydrolase involved in NAD metabolism
BL295_RS05900	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
BL295_RS05905	COG1534	Rna-binding protein
BL295_RS05925	COG1215	transferase activity, transferring glycosyl groups
BL295_RS05935	COG1733	regulation of RNA biosynthetic process
BL295_RS05940	COG0604	alcohol dehydrogenase
BL295_RS05945	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
BL295_RS05955	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
BL295_RS05960	COG0291	Belongs to the bacterial ribosomal protein bL35 family
BL295_RS05965	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
BL295_RS05970	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BL295_RS05975	COG1484	DNA-dependent DNA replication
BL295_RS05980	COG3611	Membrane attachment protein
BL295_RS05985	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
BL295_RS05990	COG0237	dephospho-CoA kinase activity
BL295_RS05995	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
BL295_RS06000	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BL295_RS06000	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BL295_RS06015	COG2151	metal-sulfur cluster biosynthetic enzyme
BL295_RS06020	COG0719	Fe-S assembly protein
BL295_RS06030	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BL295_RS06035	COG0719	Fe-S assembly protein
BL295_RS06060	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
BL295_RS06065	COG1674	ftsk spoiiie
BL295_RS06070	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BL295_RS06080	COG0220	tRNA (guanine-N7-)-methyltransferase activity
BL295_RS06085	COG0510	thiamine kinase activity
BL295_RS06090	COG4473	ABC transporter
BL295_RS06095	COG1131	(ABC) transporter
BL295_RS06100	COG0537	adenosine 5'-monophosphoramidase activity
BL295_RS06110	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BL295_RS06145	COG0446	pyridine nucleotide-disulphide oxidoreductase
BL295_RS06155	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BL295_RS06170	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
BL295_RS06175	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BL295_RS06175	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BL295_RS06180	COG0307	riboflavin synthase, alpha
BL295_RS06185	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BL295_RS06185	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BL295_RS06205	COG0463	Glycosyl transferase, family 2
BL295_RS06220	COG3976	FMN-binding domain protein
BL295_RS06220	COG1053	succinate dehydrogenase
BL295_RS06220	COG0431	NADPH-dependent FMN reductase
BL295_RS06230	COG0583	DNA-binding transcription factor activity
BL295_RS06245	COG3481	metal-dependent phosphohydrolase, HD sub domain
BL295_RS06250	COG4717	serine-type aminopeptidase activity
BL295_RS06255	COG0420	3'-5' exonuclease activity
BL295_RS06260	COG3679	Belongs to the UPF0342 family
BL295_RS06265	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BL295_RS06270	COG1438	arginine binding
BL295_RS06275	COG0436	Aminotransferase
BL295_RS06285	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BL295_RS06290	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BL295_RS06295	COG1376	ErfK ybiS ycfS ynhG family protein
BL295_RS06305	COG2723	6-phospho-beta-galactosidase activity
BL295_RS06310	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BL295_RS06315	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BL295_RS06320	COG1447	Phosphotransferase system cellobiose-specific component IIA
BL295_RS06340	COG0577	efflux transmembrane transporter activity
BL295_RS06340	COG1136	(ABC) transporter
BL295_RS06350	COG0018	arginyl-trna synthetase
BL295_RS06355	COG2153	protein acetylation
BL295_RS06375	COG0534	Mate efflux family protein
BL295_RS06380	COG0471	metal ion transport
BL295_RS06380	COG3273	potassium ion transport
BL295_RS06390	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
BL295_RS06395	COG0529	Catalyzes the synthesis of activated sulfate
BL295_RS06400	COG2046	Belongs to the sulfate adenylyltransferase family
BL295_RS06410	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
BL295_RS06415	COG0646	methionine synthase
BL295_RS06415	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
BL295_RS06730	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
BL295_RS06745	COG1846	Transcriptional regulator
BL295_RS06765	COG3279	Response regulator of the LytR AlgR family
BL295_RS06785	COG0561	phosphatase activity
BL295_RS06790	COG0697	spore germination
BL295_RS06800	COG0789	Transcriptional regulator
BL295_RS06830	COG1511	domain protein
BL295_RS06830	COG1511	domain protein
BL295_RS06835	COG1970	mechanosensitive ion channel activity
BL295_RS06840	COG1428	Deoxynucleoside kinase
BL295_RS06845	COG0584	glycerophosphoryl diester phosphodiesterase
BL295_RS06855	COG0395	ABC-type sugar transport system, permease component
BL295_RS06860	COG1175	transmembrane transport
BL295_RS06865	COG3842	ATPase activity
BL295_RS06875	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BL295_RS06880	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
BL295_RS06885	COG1187	pseudouridine synthase activity
BL295_RS06890	COG2244	polysaccharide biosynthetic process
BL295_RS06895	COG0495	leucyl-tRNA aminoacylation
BL295_RS06905	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
BL295_RS06920	COG0438	transferase activity, transferring glycosyl groups
BL295_RS06935	COG0477	Major facilitator Superfamily
BL295_RS06940	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
BL295_RS06950	COG0438	transferase activity, transferring glycosyl groups
BL295_RS06955	COG2040	homocysteine
BL295_RS06960	COG0833	amino acid
BL295_RS06965	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
BL295_RS07000	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BL295_RS07090	COG1368	sulfuric ester hydrolase activity
BL295_RS07095	COG4703	Protein of unknown function (DUF1797)
BL295_RS07100	COG0436	Aminotransferase
BL295_RS07105	COG1686	Belongs to the peptidase S11 family
BL295_RS07115	COG0438	transferase activity, transferring glycosyl groups
BL295_RS07120	COG0438	transferase activity, transferring glycosyl groups
BL295_RS07140	COG0542	response to heat
BL295_RS07145	COG0582	viral genome integration into host DNA
BL295_RS07155	COG4608	Belongs to the ABC transporter superfamily
BL295_RS07160	COG0444	Belongs to the ABC transporter superfamily
BL295_RS07165	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BL295_RS07170	COG0601	transmembrane transport
BL295_RS07175	COG4166	transmembrane transport
BL295_RS07210	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
BL295_RS07215	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BL295_RS07220	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
BL295_RS07225	COG1070	Carbohydrate kinase
BL295_RS07230	COG2610	gluconate transmembrane transporter activity
BL295_RS07235	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
BL295_RS07240	COG0628	permease
BL295_RS07265	COG3557	Belongs to the UPF0374 family
BL295_RS07270	COG2137	regulation of response to DNA damage stimulus
BL295_RS07305	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
BL295_RS07320	COG2801	Transposase and inactivated derivatives
BL295_RS07335	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
BL295_RS07345	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
BL295_RS07355	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BL295_RS07380	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BL295_RS07395	COG0513	Belongs to the DEAD box helicase family
BL295_RS07400	COG0673	inositol 2-dehydrogenase activity
BL295_RS07405	COG1278	Cold shock
BL295_RS07420	COG1737	Transcriptional regulator
BL295_RS07430	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BL295_RS07445	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BL295_RS07450	COG1597	lipid kinase activity
BL295_RS07455	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
BL295_RS07460	COG0154	amidase activity
BL295_RS07465	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
BL295_RS07470	COG4851	CamS sex pheromone cAM373 precursor
BL295_RS07475	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
BL295_RS07485	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
BL295_RS07490	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
BL295_RS07495	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BL295_RS07500	COG1705	Flagellar rod assembly protein muramidase FlgJ
BL295_RS07520	COG0142	geranyltranstransferase activity
BL295_RS07535	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
BL295_RS07540	COG4988	ABC transporter
BL295_RS07545	COG1294	oxidase, subunit
BL295_RS07550	COG1271	oxidase subunit
BL295_RS07560	COG4684	Psort location CytoplasmicMembrane, score
BL295_RS07565	COG0531	amino acid
BL295_RS07585	COG0583	DNA-binding transcription factor activity
BL295_RS07640	COG0471	metal ion transport
BL295_RS07645	COG0039	L-malate dehydrogenase activity
BL295_RS07655	COG0803	Belongs to the bacterial solute-binding protein 9 family
BL295_RS07660	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BL295_RS07665	COG1121	(ABC) transporter
BL295_RS07670	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
BL295_RS07675	COG4977	sequence-specific DNA binding
BL295_RS07675	COG1917	Cupin 2, conserved barrel domain protein
BL295_RS07685	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
BL295_RS07690	COG2151	metal-sulfur cluster biosynthetic enzyme
BL295_RS07695	COG0471	metal ion transport
BL295_RS07705	COG1271	oxidase subunit
BL295_RS07715	COG4684	Psort location CytoplasmicMembrane, score
BL295_RS07720	COG0531	amino acid
BL295_RS07730	COG0281	malic enzyme
BL295_RS07735	COG0583	DNA-binding transcription factor activity
BL295_RS07740	COG0583	DNA-binding transcription factor activity
BL295_RS07750	COG1053	succinate dehydrogenase
BL295_RS07755	COG0114	fumarate hydratase activity
BL295_RS07775	COG3052	prosthetic group binding
BL295_RS07795	COG0471	metal ion transport
BL295_RS07800	COG0039	L-malate dehydrogenase activity
BL295_RS07810	COG0803	Belongs to the bacterial solute-binding protein 9 family
BL295_RS07815	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BL295_RS07820	COG1121	(ABC) transporter
BL295_RS07830	COG1917	Cupin 2, conserved barrel domain protein
BL295_RS07830	COG4977	sequence-specific DNA binding
BL295_RS07840	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
BL295_RS07845	COG2151	metal-sulfur cluster biosynthetic enzyme
BL295_RS07850	COG0471	metal ion transport
BL295_RS07855	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
BL295_RS07860	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
BL295_RS07870	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
BL295_RS07890	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
BL295_RS07895	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
BL295_RS07900	COG0101	tRNA pseudouridine synthase activity
BL295_RS07910	COG1122	ATPase activity
BL295_RS07915	COG1122	ATPase activity
BL295_RS07925	COG4939	FMN-binding domain protein
BL295_RS07950	COG0203	ribosomal protein L17
BL295_RS07955	COG0202	RNA polymerase activity
BL295_RS07960	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
BL295_RS07965	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
BL295_RS07970	COG0257	Belongs to the bacterial ribosomal protein bL36 family
BL295_RS07975	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
BL295_RS07980	COG0563	adenylate kinase activity
BL295_RS07990	COG0200	Binds to the 23S rRNA
BL295_RS07995	COG1841	ribosomal large subunit assembly
BL295_RS08000	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
BL295_RS08005	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
BL295_RS08010	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
BL295_RS08015	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
BL295_RS08020	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
BL295_RS08025	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
BL295_RS08030	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
BL295_RS08035	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
BL295_RS08040	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
BL295_RS08045	COG0255	Belongs to the universal ribosomal protein uL29 family
BL295_RS08050	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
BL295_RS08055	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
BL295_RS08060	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
BL295_RS08065	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
BL295_RS08070	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
BL295_RS08075	COG0089	rRNA binding
BL295_RS08080	COG0088	Forms part of the polypeptide exit tunnel
BL295_RS08085	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
BL295_RS08090	COG0051	transcription antitermination factor activity, RNA binding
BL295_RS08095	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
BL295_RS08100	COG0049	tRNA binding
BL295_RS08105	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
BL295_RS08115	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
BL295_RS08120	COG0085	RNA polymerase activity
BL295_RS08130	COG0542	response to heat
BL295_RS08135	COG4463	regulation of RNA biosynthetic process
BL295_RS08175	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
BL295_RS08180	COG1428	Deoxynucleoside kinase
BL295_RS08190	COG0833	amino acid
BL295_RS08195	COG0028	Belongs to the TPP enzyme family
BL295_RS08200	COG1959	2 iron, 2 sulfur cluster binding
BL295_RS08220	COG1316	TRANSCRIPTIONal
BL295_RS08230	COG2966	Psort location CytoplasmicMembrane, score
BL295_RS08235	COG1278	Cold shock
BL295_RS08255	COG2814	Major facilitator Superfamily
BL295_RS08300	COG0367	asparagine synthase
BL295_RS08305	COG0527	aspartate kinase activity
BL295_RS08310	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
BL295_RS08360	COG0640	Transcriptional regulator
BL295_RS08365	COG0564	pseudouridine synthase activity
BL295_RS08370	COG0514	ATP-dependent DNA helicase (RecQ)
BL295_RS08390	COG4690	dipeptidase activity
BL295_RS08395	COG2502	aspartate--ammonia ligase
BL295_RS08400	COG0017	Asparaginyl-tRNA synthetase
BL295_RS08405	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
BL295_RS08415	COG1053	succinate dehydrogenase
BL295_RS08420	COG0583	DNA-binding transcription factor activity
BL295_RS08435	COG0572	uridine kinase
BL295_RS08480	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
BL295_RS08485	COG0308	aminopeptidase N
BL295_RS08515	COG1302	Protein conserved in bacteria
BL295_RS08530	COG2261	transglycosylase associated protein
BL295_RS08535	COG2755	lipolytic protein G-D-S-L family
BL295_RS08535	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
BL295_RS08555	COG2801	Transposase and inactivated derivatives
BL295_RS08565	COG1733	regulation of RNA biosynthetic process
BL295_RS08570	COG1266	CAAX protease self-immunity
BL295_RS08575	COG1396	sequence-specific DNA binding
BL295_RS08625	COG0518	GMP synthase (glutamine-hydrolyzing) activity
BL295_RS08625	COG0519	Catalyzes the synthesis of GMP from XMP
BL295_RS08630	COG1072	(Pantothenic acid kinase))
BL295_RS08635	COG2070	2-Nitropropane dioxygenase
BL295_RS08640	COG3973	AAA domain
BL295_RS08645	COG0586	Pfam SNARE associated Golgi protein
BL295_RS08650	COG0456	acetyltransferase
BL295_RS08650	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
BL295_RS08655	COG0475	glutathione-regulated potassium exporter activity
BL295_RS08655	COG0569	domain protein
BL295_RS08660	COG0588	phosphoglycerate mutase activity
BL295_RS08675	COG2076	Multidrug Resistance protein
BL295_RS08685	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BL295_RS08715	COG1846	Transcriptional regulator
BL295_RS08725	COG0531	amino acid
BL295_RS08730	COG3394	polysaccharide catabolic process
BL295_RS08735	COG1263	PTS System
BL295_RS08735	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BL295_RS08745	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BL295_RS08745	COG2190	(PTS) system
BL295_RS08745	COG1263	PTS System
BL295_RS08750	COG0765	amino acid transport
BL295_RS08755	COG0765	amino acid transport
BL295_RS08760	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BL295_RS08780	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BL295_RS08785	COG0436	Aminotransferase
BL295_RS08790	COG0546	phosphoglycolate phosphatase activity
BL295_RS08815	COG0735	belongs to the Fur family
BL295_RS08820	COG0194	GDP metabolic process
BL295_RS08840	COG0531	amino acid
BL295_RS08855	COG2936	dipeptidyl-peptidase activity
BL295_RS08860	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
BL295_RS08860	COG2755	lipolytic protein G-D-S-L family
BL295_RS08870	COG2267	carboxylic ester hydrolase activity
BL295_RS08875	COG0028	Belongs to the TPP enzyme family
BL295_RS08880	COG0196	riboflavin kinase activity
BL295_RS08885	COG0028	Belongs to the TPP enzyme family
BL295_RS08890	COG2252	PERMEase
BL295_RS08900	COG3475	LICD family
BL295_RS08910	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
BL295_RS08915	COG0248	Ppx GppA phosphatase
BL295_RS08915	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
BL295_RS08920	COG0477	Major facilitator Superfamily
BL295_RS08935	COG1393	Belongs to the ArsC family
BL295_RS08950	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
BL295_RS08970	COG0778	Nitroreductase
BL295_RS08985	COG2017	converts alpha-aldose to the beta-anomer
BL295_RS08995	COG0561	phosphatase activity
BL295_RS09005	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
BL295_RS09010	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BL295_RS09035	COG0025	NhaP-type Na H and K H
BL295_RS09040	COG0812	UDP-N-acetylmuramate dehydrogenase activity
BL295_RS09050	COG0708	Exodeoxyribonuclease III
BL295_RS09065	COG0802	atpase or kinase
BL295_RS09070	COG0280	phosphate acetyltransferase
BL295_RS09075	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
BL295_RS09080	COG0561	phosphatase activity
BL295_RS09090	COG1126	abc transporter atp-binding protein
BL295_RS09095	COG0765	amino acid transport
BL295_RS09105	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
BL295_RS09110	COG0557	exoribonuclease II activity
BL295_RS09120	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BL295_RS09125	COG0038	chloride channel
BL295_RS09135	COG0148	phosphopyruvate hydratase activity
BL295_RS09140	COG0149	triose-phosphate isomerase activity
BL295_RS09145	COG0126	phosphoglycerate kinase activity
BL295_RS09155	COG2390	Transcriptional regulator
BL295_RS09160	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
BL295_RS09170	COG0740	serine-type endopeptidase activity
BL295_RS09175	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BL295_RS09185	COG1481	regulation of sporulation
BL295_RS09195	COG1660	Displays ATPase and GTPase activities
BL295_RS09205	COG0165	Argininosuccinate lyase
BL295_RS09210	COG0137	argininosuccinate synthase activity
BL295_RS09215	COG1854	S-ribosylhomocysteine lyase activity
BL295_RS09220	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
BL295_RS09225	COG0556	nucleotide-excision repair
BL295_RS09235	COG2814	Major facilitator Superfamily
BL295_RS09245	COG0446	pyridine nucleotide-disulphide oxidoreductase
BL295_RS09255	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BL295_RS09265	COG2323	membrane
BL295_RS09270	COG0492	ferredoxin-NADP+ reductase activity
BL295_RS09275	COG0446	pyridine nucleotide-disulphide oxidoreductase
BL295_RS09285	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BL295_RS09290	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
BL295_RS09295	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
BL295_RS09300	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
BL295_RS09305	COG1950	PFAM Membrane protein of
BL295_RS09310	COG1983	PspC domain protein
BL295_RS09315	COG0704	Plays a role in the regulation of phosphate uptake
BL295_RS09320	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
BL295_RS09325	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
BL295_RS09330	COG0581	inorganic phosphate transmembrane transporter activity
BL295_RS09335	COG0573	inorganic phosphate transmembrane transporter activity
BL295_RS09340	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
BL295_RS09345	COG5002	protein histidine kinase activity
BL295_RS09350	COG0745	RESPONSE REGULATOR receiver
BL295_RS09365	COG0653	protein targeting
BL295_RS09380	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
BL295_RS09385	COG1739	Uncharacterized protein family UPF0029
BL295_RS09390	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
BL295_RS09395	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BL295_RS09400	COG0531	amino acid
BL295_RS09405	COG0459	protein refolding
BL295_RS09410	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
BL295_RS09420	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
BL295_RS09425	COG0488	(ABC) transporter
BL295_RS09435	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
BL295_RS09440	COG0456	acetyltransferase
BL295_RS09445	COG0456	acetyltransferase
BL295_RS09450	COG1214	PFAM Peptidase M22, glycoprotease
BL295_RS09460	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
BL295_RS09470	COG3639	organic phosphonate transmembrane transporter activity
BL295_RS09475	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BL295_RS09480	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
BL295_RS09485	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BL295_RS09500	COG4467	Involved in initiation control of chromosome replication
BL295_RS09505	COG0470	DNA polymerase III
BL295_RS09510	COG3870	Protein conserved in bacteria
BL295_RS09515	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
BL295_RS09530	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
BL295_RS09545	COG2813	Specifically methylates the guanine in position
BL295_RS09550	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
BL295_RS09555	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BL295_RS09565	COG1611	Belongs to the LOG family
BL295_RS09585	COG0222	ribosome binding
BL295_RS09590	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
BL295_RS09595	COG0081	regulation of translation
BL295_RS09600	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
BL295_RS09610	COG0250	Participates in transcription elongation, termination and antitermination
BL295_RS09620	COG0267	Belongs to the bacterial ribosomal protein bL33 family
BL295_RS09635	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BL295_RS09640	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
BL295_RS09645	COG0215	cysteine-tRNA ligase activity
BL295_RS09650	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BL295_RS09655	COG4956	integral membrane protein (PIN domain superfamily)
BL295_RS09680	COG0756	dUTP diphosphatase activity
BL295_RS09690	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
BL295_RS09705	COG0588	phosphoglycerate mutase activity
BL295_RS09710	COG0697	spore germination
BL295_RS09720	COG1316	TRANSCRIPTIONal
BL295_RS09725	COG0825	malonyl-CoA metabolic process
BL295_RS09735	COG0439	Biotin carboxylase
BL295_RS09745	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BL295_RS09750	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
BL295_RS09750	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BL295_RS09755	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
BL295_RS09755	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BL295_RS09760	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
BL295_RS09760	COG3933	PFAM sigma-54 factor interaction domain-containing protein
BL295_RS09770	COG3716	PTS system mannose fructose sorbose family IID component
BL295_RS09775	COG3715	PTS system
BL295_RS09795	COG0083	homoserine kinase activity
BL295_RS09800	COG0460	homoserine dehydrogenase
BL295_RS09805	COG3091	SprT-like family
BL295_RS09810	COG2183	response to ionizing radiation
BL295_RS09825	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
BL295_RS09830	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
BL295_RS09840	COG2188	Transcriptional regulator
BL295_RS09850	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BL295_RS09900	COG3104	oligopeptide transport
BL295_RS09940	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
BL295_RS09945	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BL295_RS09950	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
BL295_RS09965	COG0037	tRNA processing
BL295_RS09970	COG1098	S1 RNA binding domain
BL295_RS09980	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
BL295_RS09985	COG2244	polysaccharide biosynthetic process
BL295_RS09990	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
BL295_RS09995	COG0193	aminoacyl-tRNA hydrolase activity
BL295_RS10000	COG0039	L-malate dehydrogenase activity
BL295_RS10020	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
BL295_RS10025	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BL295_RS10030	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
BL295_RS10035	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
BL295_RS10040	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
BL295_RS10045	COG0505	Belongs to the CarA family
BL295_RS10050	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
BL295_RS10070	COG3158	transport of potassium into the cell
BL295_RS10075	COG2337	Toxic component of a toxin-antitoxin (TA) module
BL295_RS10080	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BL295_RS10085	COG0736	holo-[acyl-carrier-protein] synthase activity
BL295_RS10105	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
BL295_RS10115	COG0501	Belongs to the peptidase M48B family
BL295_RS10120	COG1704	LemA family
BL295_RS10125	COG3764	Sortase (surface protein transpeptidase)
BL295_RS10135	COG0254	rRNA binding
BL295_RS10140	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
BL295_RS10145	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
BL295_RS10160	COG1760	l-serine dehydratase
BL295_RS10165	COG1760	l-serine dehydratase
BL295_RS10175	COG0814	amino acid
BL295_RS10180	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
BL295_RS10185	COG0504	CTP synthase activity
BL295_RS10190	COG3343	RNA polymerase activity
BL295_RS10200	COG0095	Lipoate-protein ligase
BL295_RS10205	COG1078	dGTPase activity
BL295_RS10225	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
BL295_RS10235	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
BL295_RS10240	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BL295_RS10265	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BL295_RS10265	COG1321	iron dependent repressor
BL295_RS10270	COG1121	(ABC) transporter
BL295_RS10275	COG1073	alpha beta
BL295_RS10280	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
BL295_RS10285	COG4466	Protein conserved in bacteria
BL295_RS10290	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
BL295_RS10295	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
BL295_RS10300	COG0084	hydrolase, TatD family'
BL295_RS10315	COG2814	Major facilitator Superfamily
BL295_RS10320	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BL295_RS10320	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BL295_RS10330	COG1801	Protein of unknown function DUF72
BL295_RS10335	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
BL295_RS10350	COG0248	Ppx GppA phosphatase
BL295_RS10355	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BL295_RS10380	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BL295_RS10385	COG2188	Transcriptional regulator
BL295_RS10390	COG0180	Tryptophanyl-tRNA synthetase
BL295_RS10395	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BL295_RS10400	COG3973	AAA domain
BL295_RS10440	COG2274	protein secretion by the type I secretion system
BL295_RS10470	COG3328	transposase activity
BL295_RS10500	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
BL295_RS10510	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
BL295_RS10520	COG1125	glycine betaine transport
BL295_RS10535	COG0300	oxidoreductase activity
BL295_RS10565	COG1881	PFAM PEBP family protein
BL295_RS10570	COG3759	membrane
BL295_RS10580	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
BL295_RS10600	COG0004	ammonium transporteR
BL295_RS10605	COG2814	Major facilitator Superfamily
BL295_RS10620	COG1134	teichoic acid transport
BL295_RS10625	COG1682	transport, permease protein
BL295_RS10635	COG0436	Aminotransferase
BL295_RS10650	COG1268	BioY protein
BL295_RS10685	COG1012	belongs to the aldehyde dehydrogenase family
BL295_RS10685	COG1454	alcohol dehydrogenase
BL295_RS10695	COG1131	(ABC) transporter
BL295_RS10700	COG1725	Transcriptional regulator
BL295_RS10730	COG3842	ATPase activity
BL295_RS10755	COG1252	NADH dehydrogenase
BL295_RS10760	COG1846	Transcriptional regulator
BL295_RS10770	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
BL295_RS10805	COG0741	lytic transglycosylase activity
BL295_RS10820	COG1136	(ABC) transporter
BL295_RS10825	COG0577	efflux transmembrane transporter activity
BL295_RS10835	COG2818	Glycosylase
BL295_RS10840	COG2409	Drug exporters of the RND superfamily
BL295_RS10840	COG1033	growth of symbiont in host cell
BL295_RS10840	COG2409	Drug exporters of the RND superfamily
BL295_RS10840	COG1033	growth of symbiont in host cell
BL295_RS10850	COG2357	RelA SpoT domain protein
BL295_RS10860	COG0277	FAD linked oxidase domain protein
BL295_RS10865	COG1316	TRANSCRIPTIONal
BL295_RS10880	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BL295_RS10885	COG1737	Transcriptional regulator
BL295_RS10895	COG0745	RESPONSE REGULATOR receiver
BL295_RS10900	COG5002	protein histidine kinase activity
BL295_RS10910	COG2814	Major facilitator Superfamily
BL295_RS10930	COG1914	H( )-stimulated, divalent metal cation uptake system
BL295_RS10935	COG1309	transcriptional regulator
BL295_RS10940	COG1959	2 iron, 2 sulfur cluster binding
BL295_RS10950	COG0163	prenyltransferase activity
BL295_RS10955	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
BL295_RS10960	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
BL295_RS10965	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
BL295_RS10980	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BL295_RS10980	COG2190	(PTS) system
BL295_RS10980	COG1263	PTS System
BL295_RS10985	COG0366	Alpha amylase catalytic
BL295_RS10990	COG2188	Transcriptional regulator
BL295_RS11020	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BL295_RS11025	COG0626	cystathionine gamma-synthase activity
BL295_RS11030	COG1045	serine acetyltransferase
BL295_RS11035	COG0431	NADPH-dependent FMN reductase
BL295_RS11065	COG3118	belongs to the thioredoxin family
BL295_RS11075	COG0246	Mannitol dehydrogenase
BL295_RS11080	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
BL295_RS11090	COG2213	PTS system mannitol-specific
BL295_RS11115	COG0363	glucosamine-6-phosphate deaminase activity
BL295_RS11130	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BL295_RS11140	COG0386	Belongs to the glutathione peroxidase family
BL295_RS11150	COG4172	Belongs to the ABC transporter superfamily
BL295_RS11180	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
BL295_RS11185	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
BL295_RS11215	COG0667	Aldo Keto reductase
BL295_RS11220	COG0406	alpha-ribazole phosphatase activity
BL295_RS11225	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
BL295_RS11230	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BL295_RS11240	COG4166	transmembrane transport
BL295_RS11245	COG4166	transmembrane transport
BL295_RS11270	COG1757	Na H antiporter
BL295_RS11325	COG3842	ATPase activity
BL295_RS11340	COG3833	ABC-type maltose transport systems, permease component
BL295_RS11345	COG1175	transmembrane transport
BL295_RS11350	COG2182	Extracellular solute-binding protein
BL295_RS11355	COG0366	Alpha amylase catalytic
BL295_RS11360	COG1609	Transcriptional regulator
BL295_RS11365	COG1609	Transcriptional regulator
BL295_RS11370	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
BL295_RS11375	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
BL295_RS11380	COG1461	Dihydroxyacetone kinase
BL295_RS11385	COG2376	Dihydroxyacetone kinase
BL295_RS11390	COG2376	Dihydroxyacetone kinase
BL295_RS11395	COG1309	transcriptional regulator
BL295_RS11400	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
BL295_RS11405	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
BL295_RS11420	COG1131	(ABC) transporter
BL295_RS11425	COG1028	Short-chain dehydrogenase reductase Sdr
BL295_RS11450	COG2188	Transcriptional regulator
BL295_RS11460	COG4720	Psort location CytoplasmicMembrane, score
BL295_RS11465	COG1122	ATPase activity
BL295_RS11470	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
BL295_RS11505	COG0656	L-ascorbic acid biosynthetic process
BL295_RS11510	COG2807	transmembrane transport
BL295_RS11550	COG1983	PspC domain protein
BL295_RS11560	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
BL295_RS11565	COG2267	carboxylic ester hydrolase activity
BL295_RS11575	COG1113	amino acid transport
BL295_RS11590	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
BL295_RS11600	COG0352	thiamine-phosphate diphosphorylase activity
BL295_RS11605	COG0351	phosphomethylpyrimidine kinase
BL295_RS11610	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
BL295_RS11620	COG1606	tRNA processing
BL295_RS11625	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
BL295_RS11630	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
BL295_RS11635	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
BL295_RS11640	COG1691	(AIR) carboxylase
BL295_RS11645	COG3875	lactate racemase activity
BL295_RS11650	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BL295_RS11655	COG0310	cobalt ion transport
BL295_RS11660	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
BL295_RS11665	COG1122	ATPase activity
BL295_RS11690	COG4166	transmembrane transport
BL295_RS11700	COG3022	response to hydroperoxide
BL295_RS11705	COG2267	carboxylic ester hydrolase activity
BL295_RS11730	COG0604	alcohol dehydrogenase
BL295_RS11765	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
BL295_RS11785	COG2368	4-hydroxyphenylacetate
BL295_RS11805	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BL295_RS11815	COG2508	Transcriptional regulator
BL295_RS11820	COG0778	Nitroreductase
BL295_RS11830	COG1028	Short-chain dehydrogenase reductase Sdr
BL295_RS11835	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BL295_RS11850	COG0471	metal ion transport
BL295_RS11855	COG0431	NADPH-dependent FMN reductase
BL295_RS11855	COG1053	succinate dehydrogenase
BL295_RS11855	COG3976	FMN-binding domain protein
BL295_RS11875	COG1573	uracil-dna glycosylase
BL295_RS11880	COG3586	endonuclease activity
BL295_RS11885	COG1012	belongs to the aldehyde dehydrogenase family
BL295_RS11895	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
BL295_RS11900	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BL295_RS11905	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
BL295_RS11910	COG4853	Protein conserved in bacteria
BL295_RS11920	COG5002	protein histidine kinase activity
BL295_RS11925	COG0745	RESPONSE REGULATOR receiver
BL295_RS11940	COG1278	Cold shock
BL295_RS11950	COG1554	hydrolase, family 65, central catalytic
BL295_RS11955	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BL295_RS11965	COG0366	Alpha amylase catalytic
BL295_RS11965	COG3103	Sh3 type 3 domain protein
BL295_RS11970	COG0058	SHG alpha-glucan phosphorylase activity
BL295_RS11975	COG0297	glycogen (starch) synthase activity
BL295_RS11980	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
BL295_RS11985	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
BL295_RS11990	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
BL295_RS11995	COG4166	transmembrane transport
BL295_RS12000	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
BL295_RS12005	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
BL295_RS12010	COG2814	Major facilitator Superfamily
BL295_RS12015	COG0305	Participates in initiation and elongation during chromosome replication
BL295_RS12020	COG0359	binds to the 23S rRNA
BL295_RS12030	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
BL295_RS12035	COG0629	single-stranded DNA binding
BL295_RS12040	COG0360	Binds together with S18 to 16S ribosomal RNA
BL295_RS12050	COG0187	DNA topoisomerase II activity
BL295_RS12055	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
BL295_RS12060	COG2501	S4 domain
BL295_RS12065	COG0592	DNA-directed DNA polymerase activity
BL295_RS12070	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
BL295_RS12075	COG0230	Belongs to the bacterial ribosomal protein bL34 family
BL295_RS12080	COG0594	ribonuclease P activity
BL295_RS12085	COG0706	membrane insertase activity
BL295_RS12090	COG4166	transmembrane transport
BL295_RS12100	COG1847	R3H domain protein
BL295_RS12105	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
BL295_RS12110	COG0445	tRNA wobble uridine modification
BL295_RS12150	COG1307	EDD domain protein, DegV family
BL295_RS12165	COG3479	Phenolic acid decarboxylase
BL295_RS12170	COG1695	Transcriptional regulator
BL295_RS12180	COG1012	belongs to the aldehyde dehydrogenase family
BL295_RS12180	COG1454	alcohol dehydrogenase
BL295_RS12200	COG1609	Transcriptional regulator
BL295_RS12210	COG1869	D-ribose catabolic process
BL295_RS12215	COG4975	Glucose uptake
BL295_RS12235	COG3730	PTS system glucitol sorbitol-specific
BL295_RS12240	COG3732	PTS system glucitol sorbitol-specific
BL295_RS12250	COG0028	Belongs to the TPP enzyme family
BL295_RS12255	COG1959	2 iron, 2 sulfur cluster binding
BL295_RS12260	COG0028	Belongs to the TPP enzyme family
BL295_RS12265	COG1304	FMN binding
BL295_RS12280	COG4512	PFAM Accessory gene regulator B
BL295_RS12300	COG1393	Belongs to the ArsC family
BL295_RS12320	COG2261	transglycosylase associated protein
BL295_RS12345	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
BL295_RS12350	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BL295_RS12370	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BL295_RS12390	COG1737	Transcriptional regulator
BL295_RS12395	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
BL295_RS12400	COG1349	DNA-binding transcription factor activity
BL295_RS12410	COG3414	Phosphotransferase system galactitol-specific IIB component
BL295_RS12415	COG3775	system Galactitol-specific IIC component
BL295_RS12430	COG3711	transcriptional antiterminator
BL295_RS12450	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
BL295_RS12480	COG3328	transposase activity
BL295_RS12495	COG2211	Major facilitator Superfamily
BL295_RS12515	COG1263	PTS System
BL295_RS12515	COG2190	(PTS) system
BL295_RS12515	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BL295_RS12520	COG2723	6-phospho-beta-galactosidase activity
BL295_RS12525	COG2723	6-phospho-beta-galactosidase activity
BL295_RS12530	COG3711	transcriptional antiterminator
BL295_RS12540	COG2723	6-phospho-beta-galactosidase activity
BL295_RS12555	COG2971	BadF BadG BcrA BcrD
BL295_RS12560	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
BL295_RS12565	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BL295_RS12570	COG2188	Transcriptional regulator
BL295_RS12575	COG2267	carboxylic ester hydrolase activity
BL295_RS12590	COG0583	DNA-binding transcription factor activity
BL295_RS12595	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
BL295_RS12600	COG0738	Major facilitator superfamily
BL295_RS12605	COG0710	3-dehydroquinate dehydratase activity
BL295_RS12625	COG0667	Aldo Keto reductase
BL295_RS12630	COG1609	Transcriptional regulator
BL295_RS12635	COG2017	converts alpha-aldose to the beta-anomer
BL295_RS12640	COG2190	(PTS) system
BL295_RS12640	COG2211	Major facilitator Superfamily
BL295_RS12660	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
BL295_RS12665	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BL295_RS12670	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
BL295_RS12680	COG2944	sequence-specific DNA binding
BL295_RS12715	COG0477	Major facilitator Superfamily
BL295_RS12735	COG1114	Component of the transport system for branched-chain amino acids
BL295_RS12745	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
BL295_RS12795	COG0446	pyridine nucleotide-disulphide oxidoreductase
BL295_RS12820	COG3590	peptidase
BL295_RS12825	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BL295_RS12845	COG1937	Protein conserved in bacteria
BL295_RS12850	COG3118	belongs to the thioredoxin family
BL295_RS12855	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
BL295_RS12860	COG2217	Heavy metal translocating P-type atpase
BL295_RS12875	COG2226	methyltransferase
BL295_RS12920	COG0076	glutamate decarboxylase activity
BL295_RS12945	COG2207	Transcriptional regulator
BL295_RS12980	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
BL295_RS12985	COG1968	undecaprenyl-diphosphatase activity
BL295_RS13005	COG0656	L-ascorbic acid biosynthetic process
BL295_RS13015	COG0737	Belongs to the 5'-nucleotidase family
BL295_RS13020	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
BL295_RS13075	COG0477	Major facilitator Superfamily
BL295_RS13100	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
BL295_RS13115	COG0697	spore germination
BL295_RS13135	COG0071	Belongs to the small heat shock protein (HSP20) family
BL295_RS13150	COG1194	a g-specific adenine glycosylase
BL295_RS13160	COG3189	MarR family transcriptional regulator
BL295_RS13180	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
BL295_RS13190	COG1113	amino acid transport
BL295_RS13195	COG1757	Na H antiporter
BL295_RS13205	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
BL295_RS13210	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
BL295_RS13220	COG2315	Protein conserved in bacteria
BL295_RS13230	COG2217	Heavy metal translocating P-type atpase
BL295_RS13265	COG4989	oxidoreductase activity
BL295_RS13270	COG2151	metal-sulfur cluster biosynthetic enzyme
BL295_RS13280	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
BL295_RS13285	COG1882	Formate acetyltransferase
BL295_RS13290	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BL295_RS13325	COG2826	transposase and inactivated derivatives, IS30 family
BL295_RS13335	COG0803	Belongs to the bacterial solute-binding protein 9 family
BL295_RS13355	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
BL295_RS13360	COG0302	gtp cyclohydrolase
BL295_RS13370	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
BL295_RS13390	COG0640	Transcriptional regulator
BL295_RS13395	COG1272	protein, Hemolysin III
BL295_RS13410	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
BL295_RS13415	COG0628	permease
BL295_RS13420	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
BL295_RS13425	COG3158	transport of potassium into the cell
BL295_RS13430	COG0531	amino acid
BL295_RS13440	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BL295_RS13445	COG2365	Tyrosine phosphatase family
BL295_RS13450	COG0516	GMP reductase activity
BL295_RS13455	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
BL295_RS13460	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
BL295_RS13475	COG1929	Belongs to the glycerate kinase type-1 family
BL295_RS13485	COG1562	ergosterol biosynthetic process
BL295_RS13490	COG1233	COG1233 Phytoene dehydrogenase and related
BL295_RS13495	COG2738	Putative neutral zinc metallopeptidase
BL295_RS13500	COG1307	EDD domain protein, DegV family
BL295_RS13510	COG1380	Effector of murein hydrolase LrgA
BL295_RS13535	COG0735	belongs to the Fur family
BL295_RS13565	COG2190	(PTS) system
BL295_RS13565	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BL295_RS13565	COG1263	PTS System
BL295_RS13580	COG3711	transcriptional antiterminator
BL295_RS13580	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BL295_RS13585	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BL295_RS13585	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BL295_RS13585	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BL295_RS13590	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BL295_RS13595	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BL295_RS13595	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BL295_RS13595	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BL295_RS13600	COG0383	alpha-mannosidase activity
BL295_RS13610	COG0561	phosphatase activity
BL295_RS13625	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BL295_RS13630	COG4619	ABC transporter
BL295_RS13635	COG0390	transport system, permease component
BL295_RS13645	COG1609	Transcriptional regulator
BL295_RS13650	COG0366	Alpha amylase catalytic
BL295_RS13655	COG1263	PTS System
BL295_RS13655	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BL295_RS13655	COG2190	(PTS) system
BL295_RS13680	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BL295_RS13685	COG1126	abc transporter atp-binding protein
BL295_RS13690	COG0765	amino acid transport
BL295_RS13695	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BL295_RS13700	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BL295_RS13705	COG0583	DNA-binding transcription factor activity
BL295_RS13720	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BL295_RS13725	COG0357	Ribosomal RNA small subunit methyltransferase G
BL295_RS13735	COG1192	Involved in chromosome partitioning
BL295_RS13740	COG1475	DNA binding
BL295_RS13745	COG4481	Protein conserved in bacteria
BL295_RS13750	COG0012	GTP binding
BL295_RS13760	COG0516	GMP reductase activity
BL295_RS13760	COG0517	IMP dehydrogenase activity
BL295_RS13765	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BL295_RS13785	COG1686	Belongs to the peptidase S11 family
BL295_RS13790	COG1247	-acetyltransferase
BL295_RS13830	COG0515	serine threonine protein kinase
BL295_RS13830	COG2815	serine threonine protein kinase
BL295_RS13840	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
BL295_RS13850	COG1940	carbohydrate kinase activity
BL295_RS13850	COG1846	Transcriptional regulator
BL295_RS13855	COG0628	permease
BL295_RS13860	COG0588	phosphoglycerate mutase activity
BL295_RS13870	COG2226	methyltransferase
BL295_RS13985	COG1609	Transcriptional regulator
BL295_RS14000	COG2017	converts alpha-aldose to the beta-anomer
BL295_RS14005	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BL295_RS14035	COG1131	(ABC) transporter
BL295_RS14055	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
BL295_RS14065	COG1136	(ABC) transporter
BL295_RS14065	COG0577	efflux transmembrane transporter activity
BL295_RS14105	COG0789	Transcriptional regulator
BL295_RS14125	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BL295_RS14130	COG2723	6-phospho-beta-galactosidase activity
BL295_RS14140	COG0783	Belongs to the Dps family
BL295_RS14150	COG0431	NADPH-dependent FMN reductase
BL295_RS14150	COG1053	succinate dehydrogenase
BL295_RS14150	COG3976	FMN-binding domain protein
BL295_RS14160	COG2816	NAD+ diphosphatase activity
BL295_RS14170	COG0481	GTPase activity
BL295_RS14210	COG0110	maltose O-acetyltransferase activity
BL295_RS14215	COG4221	oxidoreductase activity
BL295_RS14225	COG1309	transcriptional regulator
BL295_RS14230	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BL295_RS14240	COG1120	ATPase activity
BL295_RS14245	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BL295_RS14255	COG0477	Major facilitator Superfamily
BL295_RS14270	COG0667	Aldo Keto reductase
BL295_RS14290	COG0300	oxidoreductase activity
BL295_RS14295	COG1733	regulation of RNA biosynthetic process
BL295_RS14310	COG1012	belongs to the aldehyde dehydrogenase family
BL295_RS14320	COG1309	transcriptional regulator
BL295_RS14335	COG3279	Response regulator of the LytR AlgR family
BL295_RS14340	COG0367	asparagine synthase
BL295_RS14350	COG2814	Major facilitator Superfamily
BL295_RS14355	COG1733	regulation of RNA biosynthetic process
BL295_RS14360	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BL295_RS14400	COG1063	alcohol dehydrogenase
BL295_RS14460	COG2217	Heavy metal translocating P-type atpase
BL295_RS14480	COG0531	amino acid
BL295_RS14495	COG1028	Short-chain dehydrogenase reductase Sdr
BL295_RS14500	COG1473	amidohydrolase
BL295_RS14510	COG1132	(ABC) transporter
BL295_RS14515	COG1132	(ABC) transporter
BL295_RS14525	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BL295_RS14570	COG0741	lytic transglycosylase activity
BL295_RS14575	COG0789	Transcriptional regulator
BL295_RS14585	COG2723	6-phospho-beta-galactosidase activity
BL295_RS14590	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BL295_RS14595	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BL295_RS14630	COG1136	(ABC) transporter
BL295_RS14630	COG0577	efflux transmembrane transporter activity
BL295_RS14645	COG0640	Transcriptional regulator
BL295_RS14665	COG1914	H( )-stimulated, divalent metal cation uptake system
BL295_RS14675	COG2246	polysaccharide biosynthetic process
BL295_RS14680	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BL295_RS14680	COG5549	protein import
BL295_RS14690	COG2826	transposase and inactivated derivatives, IS30 family
BL295_RS14700	COG0559	Belongs to the binding-protein-dependent transport system permease family
BL295_RS14715	COG0410	ABC transporter
BL295_RS14750	COG4120	Belongs to the binding-protein-dependent transport system permease family
BL295_RS14755	COG1116	anion transmembrane transporter activity
BL295_RS14760	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BL295_RS14760	COG2190	(PTS) system
BL295_RS14760	COG1263	PTS System
BL295_RS14765	COG0778	Nitroreductase
BL295_RS14770	COG0561	phosphatase activity
BL295_RS14775	COG1609	Transcriptional regulator
BL295_RS14785	COG1132	(ABC) transporter
BL295_RS14790	COG3409	Peptidoglycan-binding domain 1 protein
BL295_RS14795	COG1940	carbohydrate kinase activity
BL295_RS14820	COG0697	spore germination
BL295_RS14980	COG1192	Involved in chromosome partitioning
BL295_RS14995	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BL295_RS15045	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
BL295_RS15060	COG0534	Mate efflux family protein
BL295_RS15090	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
BL295_RS15095	COG2826	transposase and inactivated derivatives, IS30 family
BL295_RS15100	COG4464	protein tyrosine phosphatase activity
BL295_RS15105	COG0489	protein tyrosine kinase activity
BL295_RS15125	COG3328	transposase activity
BL295_RS15130	COG1216	Glycosyl transferase, family 2
BL295_RS15140	COG0463	Glycosyl transferase, family 2
BL295_RS15140	COG1216	Glycosyl transferase, family 2
BL295_RS15155	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
BL295_RS15180	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
BL295_RS15215	COG3475	LICD family
BL295_RS15265	COG0542	response to heat
BL295_RS15440	COG0542	response to heat
BL295_RS15500	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
BL295_RS15510	COG0657	acetylesterase activity
BL295_RS15510	COG2755	lipolytic protein G-D-S-L family
BL295_RS15540	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BL295_RS15550	COG2826	transposase and inactivated derivatives, IS30 family
BL295_RS15560	COG2826	transposase and inactivated derivatives, IS30 family
BL295_RS15585	COG1393	Belongs to the ArsC family
BL295_RS15595	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
BL295_RS15635	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BL295_RS15650	COG1192	Involved in chromosome partitioning
BL295_RS15665	COG2814	Major facilitator Superfamily
BL295_RS15805	COG0586	Pfam SNARE associated Golgi protein
BL295_RS15815	COG0745	RESPONSE REGULATOR receiver
BL295_RS15825	COG2217	Heavy metal translocating P-type atpase
BL295_RS15840	COG2826	transposase and inactivated derivatives, IS30 family
BL295_RS15910	COG0446	pyridine nucleotide-disulphide oxidoreductase
BL295_RS15920	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
BL295_RS15930	COG2826	transposase and inactivated derivatives, IS30 family
BL295_RS15945	COG1621	beta-fructofuranosidase activity
BL295_RS15950	COG1846	Transcriptional regulator
BL295_RS15990	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BL295_RS16000	COG1192	Involved in chromosome partitioning
BL295_RS16065	COG3328	transposase activity
BL295_RS16080	COG0463	Glycosyl transferase, family 2
BL295_RS16090	COG3328	transposase activity
BL295_RS16180	COG0582	viral genome integration into host DNA
BL295_RS16210	COG1376	ErfK ybiS ycfS ynhG family protein
BL295_RS16260	COG3328	transposase activity
BL295_RS16330	COG3328	transposase activity
BL295_RS16345	COG0463	Glycosyl transferase, family 2
BL295_RS16355	COG3328	transposase activity
BL295_RS16845	COG2801	Transposase and inactivated derivatives
BL295_RS17000	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
BL295_RS17005	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection