locus-tag	class	description
LACP0422_RS00040	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LACP0422_RS00045	COG1674	ftsk spoiiie
LACP0422_RS00050	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
LACP0422_RS00075	COG0719	Fe-S assembly protein
LACP0422_RS00080	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
LACP0422_RS00090	COG0719	Fe-S assembly protein
LACP0422_RS00095	COG2151	metal-sulfur cluster biosynthetic enzyme
LACP0422_RS00110	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
LACP0422_RS00110	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
LACP0422_RS00115	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
LACP0422_RS00120	COG0237	dephospho-CoA kinase activity
LACP0422_RS00125	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
LACP0422_RS00130	COG3611	Membrane attachment protein
LACP0422_RS00135	COG1484	DNA-dependent DNA replication
LACP0422_RS00140	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
LACP0422_RS00145	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
LACP0422_RS00150	COG0291	Belongs to the bacterial ribosomal protein bL35 family
LACP0422_RS00155	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
LACP0422_RS00165	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
LACP0422_RS00170	COG0604	alcohol dehydrogenase
LACP0422_RS00175	COG1733	regulation of RNA biosynthetic process
LACP0422_RS00185	COG1215	transferase activity, transferring glycosyl groups
LACP0422_RS00200	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
LACP0422_RS00205	COG1534	Rna-binding protein
LACP0422_RS00210	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
LACP0422_RS00215	COG1713	HD superfamily hydrolase involved in NAD metabolism
LACP0422_RS00220	COG0799	negative regulation of ribosome biogenesis
LACP0422_RS00225	COG2226	methyltransferase
LACP0422_RS00230	COG1323	Belongs to the UPF0348 family
LACP0422_RS00240	COG0333	Belongs to the bacterial ribosomal protein bL32 family
LACP0422_RS00255	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
LACP0422_RS00260	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
LACP0422_RS00265	COG0745	RESPONSE REGULATOR receiver
LACP0422_RS00270	COG5002	protein histidine kinase activity
LACP0422_RS00280	COG0419	ATPase involved in DNA repair
LACP0422_RS00295	COG0706	membrane insertase activity
LACP0422_RS00300	COG1254	Belongs to the acylphosphatase family
LACP0422_RS00305	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LACP0422_RS00315	COG1733	regulation of RNA biosynthetic process
LACP0422_RS00320	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
LACP0422_RS00325	COG0072	phenylalanine-tRNA ligase activity
LACP0422_RS00325	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LACP0422_RS00330	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
LACP0422_RS00335	COG0572	uridine kinase
LACP0422_RS00340	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
LACP0422_RS00355	COG4841	protein insertion into membrane
LACP0422_RS00365	COG0768	penicillin binding
LACP0422_RS00370	COG0267	Belongs to the bacterial ribosomal protein bL33 family
LACP0422_RS00375	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
LACP0422_RS00380	COG0705	Rhomboid family
LACP0422_RS00380	COG0457	Tetratricopeptide repeat
LACP0422_RS00390	COG1940	carbohydrate kinase activity
LACP0422_RS00410	COG0584	glycerophosphoryl diester phosphodiesterase
LACP0422_RS00415	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
LACP0422_RS00420	COG0789	Transcriptional regulator
LACP0422_RS00470	COG0261	This protein binds to 23S rRNA in the presence of protein L20
LACP0422_RS00480	COG0211	Belongs to the bacterial ribosomal protein bL27 family
LACP0422_RS00485	COG0006	proline dipeptidase activity
LACP0422_RS00490	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
LACP0422_RS00495	COG1302	Protein conserved in bacteria
LACP0422_RS00500	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
LACP0422_RS00505	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
LACP0422_RS00510	COG1570	exodeoxyribonuclease VII activity
LACP0422_RS00515	COG1722	exodeoxyribonuclease VII activity
LACP0422_RS00520	COG0142	geranyltranstransferase activity
LACP0422_RS00525	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
LACP0422_RS00530	COG1438	arginine binding
LACP0422_RS00535	COG0497	DNA recombination
LACP0422_RS00550	COG1732	Glycine betaine
LACP0422_RS00565	COG0194	GDP metabolic process
LACP0422_RS00570	COG1758	RNA polymerase activity
LACP0422_RS00575	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
LACP0422_RS00580	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
LACP0422_RS00585	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
LACP0422_RS00590	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
LACP0422_RS00590	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
LACP0422_RS00595	COG0631	protein serine/threonine phosphatase activity
LACP0422_RS00600	COG2815	serine threonine protein kinase
LACP0422_RS00600	COG0515	serine threonine protein kinase
LACP0422_RS00605	COG1162	GTPase activity
LACP0422_RS00610	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
LACP0422_RS00615	COG1564	THIamine pyrophosphokinase
LACP0422_RS00625	COG0227	Belongs to the bacterial ribosomal protein bL28 family
LACP0422_RS00630	COG1302	Protein conserved in bacteria
LACP0422_RS00635	COG1461	Dihydroxyacetone kinase
LACP0422_RS00640	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
LACP0422_RS00645	COG0416	fatty acid biosynthetic process
LACP0422_RS00650	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LACP0422_RS00655	COG0571	ribonuclease III activity
LACP0422_RS00660	COG1196	nuclear chromosome segregation
LACP0422_RS00665	COG0552	protein localization to endoplasmic reticulum
LACP0422_RS00670	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
LACP0422_RS00675	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
LACP0422_RS00680	COG0228	four-way junction DNA binding
LACP0422_RS00685	COG1837	Belongs to the UPF0109 family
LACP0422_RS00690	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
LACP0422_RS00695	COG0336	Belongs to the RNA methyltransferase TrmD family
LACP0422_RS00700	COG0335	large ribosomal subunit rRNA binding
LACP0422_RS00735	COG0512	Glutamine amidotransferase of anthranilate synthase
LACP0422_RS00735	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
LACP0422_RS00740	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
LACP0422_RS00745	COG0134	indole-3-glycerol-phosphate synthase activity
LACP0422_RS00750	COG0135	phosphoribosylanthranilate isomerase activity
LACP0422_RS00755	COG0133	tryptophan synthase activity
LACP0422_RS00760	COG0159	tryptophan synthase activity
LACP0422_RS00775	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LACP0422_RS00785	COG1473	amidohydrolase
LACP0422_RS00790	COG1063	alcohol dehydrogenase
LACP0422_RS00800	COG0300	oxidoreductase activity
LACP0422_RS00810	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
LACP0422_RS00815	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
LACP0422_RS00820	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LACP0422_RS00825	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
LACP0422_RS00830	COG1028	Short-chain dehydrogenase reductase Sdr
LACP0422_RS00835	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
LACP0422_RS00850	COG0439	Biotin carboxylase
LACP0422_RS00865	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
LACP0422_RS00875	COG1811	Na channel or pump
LACP0422_RS00880	COG0583	DNA-binding transcription factor activity
LACP0422_RS00885	COG1607	acyl-coa hydrolase
LACP0422_RS00890	COG1162	GTPase activity
LACP0422_RS00900	COG0477	Major facilitator Superfamily
LACP0422_RS00950	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
LACP0422_RS00955	COG3397	chitin binding
LACP0422_RS00970	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
LACP0422_RS00980	COG3152	Membrane
LACP0422_RS00985	COG1597	lipid kinase activity
LACP0422_RS00995	COG2261	transglycosylase associated protein
LACP0422_RS01000	COG3237	CsbD-like
LACP0422_RS01015	COG1942	4-Oxalocrotonate Tautomerase
LACP0422_RS01050	COG0531	amino acid
LACP0422_RS01055	COG0561	phosphatase activity
LACP0422_RS01060	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
LACP0422_RS01060	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
LACP0422_RS01080	COG2017	converts alpha-aldose to the beta-anomer
LACP0422_RS01085	COG1304	FMN binding
LACP0422_RS01100	COG0083	homoserine kinase activity
LACP0422_RS01105	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
LACP0422_RS01105	COG1199	ATP-dependent helicase activity
LACP0422_RS01120	COG0017	Asparaginyl-tRNA synthetase
LACP0422_RS01130	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
LACP0422_RS01135	COG2011	ABC-type metal ion transport system permease component
LACP0422_RS01140	COG1464	Belongs to the NlpA lipoprotein family
LACP0422_RS01150	COG1177	transmembrane transport
LACP0422_RS01155	COG1840	ABC-type Fe3 transport system, periplasmic component
LACP0422_RS01170	COG3331	DNA recombination
LACP0422_RS01175	COG4474	Belongs to the UPF0398 family
LACP0422_RS01180	COG3599	regulation of cell shape
LACP0422_RS01190	COG0116	Belongs to the methyltransferase superfamily
LACP0422_RS01195	COG1073	alpha beta
LACP0422_RS01205	COG1216	Glycosyl transferase, family 2
LACP0422_RS01225	COG1619	proteins homologs of microcin C7 resistance protein MccF
LACP0422_RS01250	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
LACP0422_RS01265	COG2759	Belongs to the formate--tetrahydrofolate ligase family
LACP0422_RS01270	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
LACP0422_RS01275	COG0564	pseudouridine synthase activity
LACP0422_RS01280	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
LACP0422_RS01285	COG0505	Belongs to the CarA family
LACP0422_RS01290	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
LACP0422_RS01305	COG5646	InterPro IPR014922
LACP0422_RS01330	COG1131	(ABC) transporter
LACP0422_RS01335	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
LACP0422_RS01340	COG1293	RNA-binding protein homologous to eukaryotic snRNP
LACP0422_RS01350	COG1307	EDD domain protein, DegV family
LACP0422_RS01405	COG1113	amino acid transport
LACP0422_RS01425	COG1620	l-lactate permease
LACP0422_RS01435	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
LACP0422_RS01460	COG1846	Transcriptional regulator
LACP0422_RS01465	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LACP0422_RS01500	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
LACP0422_RS01505	COG1227	inorganic diphosphatase activity
LACP0422_RS01510	COG0583	DNA-binding transcription factor activity
LACP0422_RS01520	COG0187	DNA topoisomerase II activity
LACP0422_RS01525	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
LACP0422_RS01535	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
LACP0422_RS01540	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
LACP0422_RS01545	COG4974	Belongs to the 'phage' integrase family
LACP0422_RS01550	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
LACP0422_RS01555	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
LACP0422_RS01560	COG0758	DNA mediated transformation
LACP0422_RS01565	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
LACP0422_RS01570	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
LACP0422_RS01575	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
LACP0422_RS01580	COG0583	DNA-binding transcription factor activity
LACP0422_RS01595	COG2814	Major facilitator Superfamily
LACP0422_RS01615	COG0793	Belongs to the peptidase S41A family
LACP0422_RS01615	COG3409	Peptidoglycan-binding domain 1 protein
LACP0422_RS01620	COG4479	Belongs to the UPF0346 family
LACP0422_RS01625	COG4698	Protein conserved in bacteria
LACP0422_RS01630	COG2755	lipolytic protein G-D-S-L family
LACP0422_RS01635	COG1307	EDD domain protein, DegV family
LACP0422_RS01640	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
LACP0422_RS01645	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
LACP0422_RS01650	COG0488	(ABC) transporter
LACP0422_RS01660	COG0617	tRNA 3'-terminal CCA addition
LACP0422_RS01665	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
LACP0422_RS01670	COG0561	phosphatase activity
LACP0422_RS01675	COG0457	Tetratricopeptide repeat
LACP0422_RS01685	COG1160	GTP binding
LACP0422_RS01690	COG0539	negative regulation of cytoplasmic translation
LACP0422_RS01695	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
LACP0422_RS01705	COG0514	ATP-dependent DNA helicase (RecQ)
LACP0422_RS01715	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
LACP0422_RS01720	COG1187	pseudouridine synthase activity
LACP0422_RS01725	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
LACP0422_RS01730	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
LACP0422_RS01740	COG4974	Belongs to the 'phage' integrase family
LACP0422_RS01745	COG2996	Protein conserved in bacteria
LACP0422_RS01760	COG0205	6-phosphofructokinase activity
LACP0422_RS01765	COG0587	DNA-directed DNA polymerase activity
LACP0422_RS01775	COG0542	response to heat
LACP0422_RS01785	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
LACP0422_RS01790	COG2384	SAM-dependent methyltransferase
LACP0422_RS01815	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
LACP0422_RS01815	COG0574	Belongs to the PEP-utilizing enzyme family
LACP0422_RS01825	COG1846	Transcriptional regulator
LACP0422_RS01845	COG2217	Heavy metal translocating P-type atpase
LACP0422_RS01850	COG0148	phosphopyruvate hydratase activity
LACP0422_RS01855	COG0477	Major facilitator Superfamily
LACP0422_RS01865	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
LACP0422_RS01870	COG0446	pyridine nucleotide-disulphide oxidoreductase
LACP0422_RS01875	COG1349	DNA-binding transcription factor activity
LACP0422_RS01885	COG1393	Belongs to the ArsC family
LACP0422_RS01905	COG0546	phosphoglycolate phosphatase activity
LACP0422_RS01935	COG0583	DNA-binding transcription factor activity
LACP0422_RS01940	COG0604	alcohol dehydrogenase
LACP0422_RS01950	COG0446	pyridine nucleotide-disulphide oxidoreductase
LACP0422_RS01955	COG2197	response regulator
LACP0422_RS01960	COG4585	Histidine kinase
LACP0422_RS01970	COG1131	(ABC) transporter
LACP0422_RS01980	COG0519	Catalyzes the synthesis of GMP from XMP
LACP0422_RS01995	COG1131	(ABC) transporter
LACP0422_RS02015	COG1131	(ABC) transporter
LACP0422_RS02020	COG1725	Transcriptional regulator
LACP0422_RS02025	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
LACP0422_RS02030	COG0358	DNA primase activity
LACP0422_RS02035	COG0751	glycine-tRNA ligase activity
LACP0422_RS02040	COG0752	glycyl-tRNA synthetase alpha subunit
LACP0422_RS02045	COG1381	Involved in DNA repair and RecF pathway recombination
LACP0422_RS02050	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
LACP0422_RS02055	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
LACP0422_RS02060	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
LACP0422_RS02065	COG1702	phosphate starvation-inducible protein PhoH
LACP0422_RS02070	COG1610	YqeY-like protein
LACP0422_RS02075	COG0828	Belongs to the bacterial ribosomal protein bS21 family
LACP0422_RS02080	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
LACP0422_RS02090	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
LACP0422_RS02100	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
LACP0422_RS02110	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
LACP0422_RS02115	COG0124	histidyl-tRNA synthetase
LACP0422_RS02120	COG4991	sh3 domain protein
LACP0422_RS02120	COG0860	N-Acetylmuramoyl-L-alanine amidase
LACP0422_RS02120	COG3103	Sh3 type 3 domain protein
LACP0422_RS02125	COG3001	Fructosamine kinase
LACP0422_RS02130	COG0546	phosphoglycolate phosphatase activity
LACP0422_RS02135	COG1490	D-aminoacyl-tRNA deacylase activity
LACP0422_RS02140	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
LACP0422_RS02150	COG1385	rRNA (uridine-N3-)-methyltransferase activity
LACP0422_RS02155	COG2264	protein methyltransferase activity
LACP0422_RS02160	COG2094	Belongs to the DNA glycosylase MPG family
LACP0422_RS02175	COG0481	GTPase activity
LACP0422_RS02180	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
LACP0422_RS02185	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LACP0422_RS02190	COG1696	Membrane protein involved in D-alanine export
LACP0422_RS02195	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LACP0422_RS02205	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
LACP0422_RS02210	COG0484	heat shock protein binding
LACP0422_RS02215	COG0443	Heat shock 70 kDa protein
LACP0422_RS02220	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
LACP0422_RS02225	COG1420	regulation of RNA biosynthetic process
LACP0422_RS02230	COG3527	Alpha-acetolactate decarboxylase
LACP0422_RS02235	COG0196	riboflavin kinase activity
LACP0422_RS02240	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
LACP0422_RS02245	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
LACP0422_RS02250	COG0287	Prephenate dehydrogenase
LACP0422_RS02255	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
LACP0422_RS02265	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
LACP0422_RS02270	COG0738	Major facilitator superfamily
LACP0422_RS02275	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
LACP0422_RS02280	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
LACP0422_RS02290	COG2740	Nucleic-acid-binding protein implicated in transcription termination
LACP0422_RS02295	COG0195	Participates in both transcription termination and antitermination
LACP0422_RS02300	COG0779	Required for maturation of 30S ribosomal subunits
LACP0422_RS02305	COG2176	DNA-directed DNA polymerase activity
LACP0422_RS02310	COG0442	prolyl-tRNA aminoacylation
LACP0422_RS02315	COG0750	zinc metalloprotease
LACP0422_RS02320	COG4589	Belongs to the CDS family
LACP0422_RS02325	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
LACP0422_RS02330	COG0233	cytoplasmic translational termination
LACP0422_RS02335	COG0528	UMP kinase activity
LACP0422_RS02340	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
LACP0422_RS02345	COG0052	Belongs to the universal ribosomal protein uS2 family
LACP0422_RS02355	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LACP0422_RS02360	COG2827	Endonuclease containing a URI domain
LACP0422_RS02365	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
LACP0422_RS02370	COG0204	Acyl-transferase
LACP0422_RS02375	COG3763	UPF0154 protein
LACP0422_RS02380	COG4224	UPF0291 protein
LACP0422_RS02385	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
LACP0422_RS02400	COG3425	synthase
LACP0422_RS02415	COG0463	Glycosyl transferase, family 2
LACP0422_RS02425	COG1316	TRANSCRIPTIONal
LACP0422_RS02430	COG1116	anion transmembrane transporter activity
LACP0422_RS02440	COG0772	Belongs to the SEDS family
LACP0422_RS02460	COG0393	Putative heavy-metal-binding
LACP0422_RS02475	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
LACP0422_RS02480	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
LACP0422_RS02480	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
LACP0422_RS02485	COG5416	Lipopolysaccharide assembly protein A domain
LACP0422_RS02490	COG0300	oxidoreductase activity
LACP0422_RS02495	COG1234	tRNA 3'-trailer cleavage
LACP0422_RS02505	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
LACP0422_RS02510	COG1349	DNA-binding transcription factor activity
LACP0422_RS02515	COG1105	Belongs to the carbohydrate kinase PfkB family
LACP0422_RS02520	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LACP0422_RS02520	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
LACP0422_RS02520	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LACP0422_RS02525	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
LACP0422_RS02550	COG0297	glycogen (starch) synthase activity
LACP0422_RS02555	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
LACP0422_RS02560	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LACP0422_RS02570	COG0489	protein tyrosine kinase activity
LACP0422_RS02580	COG0322	excinuclease ABC activity
LACP0422_RS02585	COG1126	abc transporter atp-binding protein
LACP0422_RS02590	COG0765	amino acid transport
LACP0422_RS02610	COG0218	Necessary for normal cell division and for the maintenance of normal septation
LACP0422_RS02615	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
LACP0422_RS02620	COG0544	peptidyl-prolyl cis-trans isomerase activity
LACP0422_RS02625	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
LACP0422_RS02650	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
LACP0422_RS02655	COG0268	Binds directly to 16S ribosomal RNA
LACP0422_RS02660	COG1466	dna polymerase III delta subunit
LACP0422_RS02665	COG2333	competence protein COMEC
LACP0422_RS02665	COG0658	competence protein
LACP0422_RS02670	COG2131	deaminase
LACP0422_RS02675	COG1555	photosystem II stabilization
LACP0422_RS02675	COG1596	polysaccharide export
LACP0422_RS02680	COG3480	Lon protease (S16) C-terminal proteolytic domain
LACP0422_RS02685	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
LACP0422_RS02690	COG0742	ribosomal rna small subunit methyltransferase
LACP0422_RS02695	COG4471	UPF0298 protein
LACP0422_RS02700	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
LACP0422_RS02705	COG0772	Belongs to the SEDS family
LACP0422_RS02730	COG1217	gtp-binding protein TYPA
LACP0422_RS02735	COG0483	inositol monophosphate 1-phosphatase activity
LACP0422_RS02740	COG4476	Belongs to the UPF0223 family
LACP0422_RS02745	COG0039	L-malate dehydrogenase activity
LACP0422_RS02770	COG0242	peptide deformylase activity
LACP0422_RS02780	COG5503	Protein of unknown function (DUF1447)
LACP0422_RS02785	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
LACP0422_RS02790	COG1597	lipid kinase activity
LACP0422_RS02800	COG3584	3D domain protein
LACP0422_RS02800	COG1388	LysM domain
LACP0422_RS02805	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
LACP0422_RS02810	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
LACP0422_RS02840	COG0569	domain protein
LACP0422_RS02845	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
LACP0422_RS02850	COG0482	sulfurtransferase activity
LACP0422_RS02860	COG1104	cysteine desulfurase activity
LACP0422_RS02865	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
LACP0422_RS02875	COG0494	nUDIX hydrolase
LACP0422_RS02880	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
LACP0422_RS02890	COG3279	Response regulator of the LytR AlgR family
LACP0422_RS02905	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
LACP0422_RS02910	COG3599	regulation of cell shape
LACP0422_RS02920	COG0762	integral membrane protein
LACP0422_RS02925	COG1799	cell septum assembly
LACP0422_RS02940	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
LACP0422_RS02945	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
LACP0422_RS02950	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
LACP0422_RS02955	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
LACP0422_RS02960	COG0768	penicillin binding
LACP0422_RS02970	COG0275	rRNA processing
LACP0422_RS02975	COG2001	Belongs to the MraZ family
LACP0422_RS02995	COG1674	ftsk spoiiie
LACP0422_RS03000	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
LACP0422_RS03010	COG1114	Component of the transport system for branched-chain amino acids
LACP0422_RS03020	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
LACP0422_RS03025	COG0628	permease
LACP0422_RS03035	COG2706	6-phosphogluconolactonase activity
LACP0422_RS03040	COG3142	Participates in the control of copper homeostasis
LACP0422_RS03045	COG0564	pseudouridine synthase activity
LACP0422_RS03050	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
LACP0422_RS03055	COG2357	RelA SpoT domain protein
LACP0422_RS03065	COG1164	Oligoendopeptidase f
LACP0422_RS03075	COG4862	establishment of competence for transformation
LACP0422_RS03080	COG1393	Belongs to the ArsC family
LACP0422_RS03085	COG1234	tRNA 3'-trailer cleavage
LACP0422_RS03230	COG1098	S1 RNA binding domain
LACP0422_RS03240	COG0586	Pfam SNARE associated Golgi protein
LACP0422_RS03250	COG0647	UMP catabolic process
LACP0422_RS03255	COG4470	Protein conserved in bacteria
LACP0422_RS03260	COG0737	Belongs to the 5'-nucleotidase family
LACP0422_RS03270	COG1113	amino acid transport
LACP0422_RS03275	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
LACP0422_RS03280	COG0827	DNA restriction-modification system
LACP0422_RS03310	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
LACP0422_RS03320	COG0217	transcriptional regulatory protein
LACP0422_RS03335	COG1609	Transcriptional regulator
LACP0422_RS03340	COG0006	proline dipeptidase activity
LACP0422_RS03345	COG0789	Transcriptional regulator
LACP0422_RS03360	COG0668	transmembrane transport
LACP0422_RS03365	COG1473	amidohydrolase
LACP0422_RS03370	COG2171	N-acyltransferase activity
LACP0422_RS03375	COG0517	IMP dehydrogenase activity
LACP0422_RS03385	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
LACP0422_RS03390	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
LACP0422_RS03395	COG1719	4-vinyl reductase, 4VR
LACP0422_RS03400	COG3118	belongs to the thioredoxin family
LACP0422_RS03405	COG1193	negative regulation of DNA recombination
LACP0422_RS03415	COG3906	Belongs to the UPF0473 family
LACP0422_RS03420	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
LACP0422_RS03425	COG4472	Bacterial protein of unknown function (DUF965)
LACP0422_RS03430	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
LACP0422_RS03435	COG0513	Belongs to the DEAD box helicase family
LACP0422_RS03440	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
LACP0422_RS03445	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
LACP0422_RS03450	COG1862	Preprotein translocase
LACP0422_RS03455	COG0343	queuine tRNA-ribosyltransferase activity
LACP0422_RS03460	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
LACP0422_RS03465	COG2255	four-way junction helicase activity
LACP0422_RS03470	COG0632	four-way junction helicase activity
LACP0422_RS03490	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
LACP0422_RS03495	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
LACP0422_RS03500	COG1692	metallophosphoesterase
LACP0422_RS03505	COG1418	mRNA catabolic process
LACP0422_RS03510	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
LACP0422_RS03515	COG1058	Belongs to the CinA family
LACP0422_RS03515	COG1546	Belongs to the CinA family
LACP0422_RS03520	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
LACP0422_RS03525	COG1426	Protein conserved in bacteria
LACP0422_RS03530	COG0612	Peptidase, M16
LACP0422_RS03535	COG0612	Peptidase, M16
LACP0422_RS03540	COG0527	aspartate kinase activity
LACP0422_RS03545	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LACP0422_RS03550	COG1126	abc transporter atp-binding protein
LACP0422_RS03555	COG0765	amino acid transport
LACP0422_RS03560	COG2894	cell division
LACP0422_RS03565	COG0850	regulation of cytokinetic process
LACP0422_RS03575	COG1792	Involved in formation and maintenance of cell shape
LACP0422_RS03580	COG1077	Cell shape determining protein MreB Mrl
LACP0422_RS03585	COG2003	Belongs to the UPF0758 family
LACP0422_RS03590	COG0285	dihydrofolate synthase activity
LACP0422_RS03595	COG0525	valine-tRNA ligase activity
LACP0422_RS03605	COG1181	Belongs to the D-alanine--D-alanine ligase family
LACP0422_RS03605	COG2918	glutathione biosynthetic process
LACP0422_RS03615	COG0301	tRNA thio-modification
LACP0422_RS03620	COG1104	cysteine desulfurase activity
LACP0422_RS03625	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
LACP0422_RS03630	COG1956	GAF domain-containing protein
LACP0422_RS03635	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
LACP0422_RS03640	COG4493	Belongs to the UPF0637 family
LACP0422_RS03655	COG0640	Transcriptional regulator
LACP0422_RS03660	COG0366	Alpha amylase catalytic
LACP0422_RS03670	COG3716	PTS system mannose fructose sorbose family IID component
LACP0422_RS03675	COG3715	PTS system
LACP0422_RS03680	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LACP0422_RS03685	COG1609	Transcriptional regulator
LACP0422_RS03690	COG0189	ligase activity
LACP0422_RS03690	COG2918	glutathione biosynthetic process
LACP0422_RS03695	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
LACP0422_RS03710	COG0589	response to stress
LACP0422_RS03730	COG1181	Belongs to the D-alanine--D-alanine ligase family
LACP0422_RS03750	COG1464	Belongs to the NlpA lipoprotein family
LACP0422_RS03755	COG2011	ABC-type metal ion transport system permease component
LACP0422_RS03760	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
LACP0422_RS03765	COG0509	glycine decarboxylation via glycine cleavage system
LACP0422_RS03770	COG0772	Belongs to the SEDS family
LACP0422_RS03780	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
LACP0422_RS03785	COG1077	Cell shape determining protein MreB Mrl
LACP0422_RS03795	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
LACP0422_RS03800	COG0355	proton-transporting ATP synthase activity, rotational mechanism
LACP0422_RS03805	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
LACP0422_RS03810	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
LACP0422_RS03815	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
LACP0422_RS03820	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
LACP0422_RS03825	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
LACP0422_RS03830	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
LACP0422_RS03835	COG0356	it plays a direct role in the translocation of protons across the membrane
LACP0422_RS03840	COG2233	PERMEase
LACP0422_RS03850	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
LACP0422_RS03855	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
LACP0422_RS03860	COG0009	L-threonylcarbamoyladenylate synthase
LACP0422_RS03865	COG2890	protein-(glutamine-N5) methyltransferase activity
LACP0422_RS03870	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
LACP0422_RS03875	COG1435	thymidine kinase activity
LACP0422_RS03880	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
LACP0422_RS03885	COG3442	glutamine amidotransferase
LACP0422_RS03890	COG1482	cell wall glycoprotein biosynthetic process
LACP0422_RS03895	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
LACP0422_RS03905	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
LACP0422_RS03920	COG1132	(ABC) transporter
LACP0422_RS03935	COG0726	polysaccharide deacetylase
LACP0422_RS04055	COG2868	ribosomal protein
LACP0422_RS04070	COG5484	DNA packaging
LACP0422_RS04180	COG1396	sequence-specific DNA binding
LACP0422_RS04220	COG1970	mechanosensitive ion channel activity
LACP0422_RS04230	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
LACP0422_RS04245	COG1192	Involved in chromosome partitioning
LACP0422_RS04300	COG4932	domain protein
LACP0422_RS04300	COG4886	Leucine-rich repeat (LRR) protein
LACP0422_RS04315	COG1132	(ABC) transporter
LACP0422_RS04325	COG1136	(ABC) transporter
LACP0422_RS04325	COG0577	efflux transmembrane transporter activity
LACP0422_RS04335	COG0166	Belongs to the GPI family
LACP0422_RS04340	COG4975	Glucose uptake
LACP0422_RS04345	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
LACP0422_RS04350	COG3850	Histidine kinase
LACP0422_RS04350	COG5002	protein histidine kinase activity
LACP0422_RS04355	COG0745	RESPONSE REGULATOR receiver
LACP0422_RS04360	COG2848	UPF0210 protein
LACP0422_RS04365	COG3830	Belongs to the UPF0237 family
LACP0422_RS04405	COG2801	Transposase and inactivated derivatives
LACP0422_RS04420	COG0477	Major facilitator Superfamily
LACP0422_RS04440	COG0791	NLP P60 protein
LACP0422_RS04445	COG1522	sequence-specific DNA binding
LACP0422_RS04465	COG0488	(ABC) transporter
LACP0422_RS04485	COG2190	(PTS) system
LACP0422_RS04485	COG1263	PTS System
LACP0422_RS04485	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LACP0422_RS04490	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
LACP0422_RS04495	COG1307	EDD domain protein, DegV family
LACP0422_RS04505	COG2873	o-acetylhomoserine
LACP0422_RS04510	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
LACP0422_RS04520	COG4120	Belongs to the binding-protein-dependent transport system permease family
LACP0422_RS04530	COG0446	pyridine nucleotide-disulphide oxidoreductase
LACP0422_RS04535	COG2084	Dehydrogenase
LACP0422_RS04540	COG0861	Integral membrane protein TerC family
LACP0422_RS04550	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
LACP0422_RS04555	COG0140	phosphoribosyl-ATP diphosphatase activity
LACP0422_RS04560	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
LACP0422_RS04565	COG0107	imidazoleglycerol-phosphate synthase activity
LACP0422_RS04570	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
LACP0422_RS04575	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
LACP0422_RS04580	COG0131	Imidazoleglycerol-phosphate dehydratase
LACP0422_RS04585	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
LACP0422_RS04590	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
LACP0422_RS04595	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
LACP0422_RS04600	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
LACP0422_RS04625	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
LACP0422_RS04640	COG3548	integral membrane protein
LACP0422_RS04660	COG1368	sulfuric ester hydrolase activity
LACP0422_RS04665	COG0584	glycerophosphoryl diester phosphodiesterase
LACP0422_RS04670	COG0492	ferredoxin-NADP+ reductase activity
LACP0422_RS04680	COG4932	domain protein
LACP0422_RS04685	COG2326	polyphosphate kinase activity
LACP0422_RS04690	COG0778	Nitroreductase
LACP0422_RS04700	COG0328	RNA-DNA hybrid ribonuclease activity
LACP0422_RS04705	COG4975	Glucose uptake
LACP0422_RS04720	COG1349	DNA-binding transcription factor activity
LACP0422_RS04725	COG1882	Formate acetyltransferase
LACP0422_RS04745	COG1609	Transcriptional regulator
LACP0422_RS04750	COG1737	Transcriptional regulator
LACP0422_RS04755	COG0673	inositol 2-dehydrogenase activity
LACP0422_RS04760	COG0673	inositol 2-dehydrogenase activity
LACP0422_RS04765	COG0025	NhaP-type Na H and K H
LACP0422_RS04770	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
LACP0422_RS04775	COG1335	isochorismatase
LACP0422_RS04785	COG1131	(ABC) transporter
LACP0422_RS04790	COG1725	Transcriptional regulator
LACP0422_RS04830	COG0028	Belongs to the TPP enzyme family
LACP0422_RS04840	COG1073	alpha beta
LACP0422_RS04845	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LACP0422_RS04850	COG0626	cystathionine gamma-synthase activity
LACP0422_RS04880	COG0095	Lipoate-protein ligase
LACP0422_RS04885	COG1705	Flagellar rod assembly protein muramidase FlgJ
LACP0422_RS04895	COG3716	PTS system mannose fructose sorbose family IID component
LACP0422_RS04900	COG3715	PTS system
LACP0422_RS04905	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LACP0422_RS04910	COG2188	Transcriptional regulator
LACP0422_RS04915	COG0589	response to stress
LACP0422_RS04920	COG0564	pseudouridine synthase activity
LACP0422_RS04925	COG1396	sequence-specific DNA binding
LACP0422_RS04940	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
LACP0422_RS04950	COG2188	Transcriptional regulator
LACP0422_RS04955	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
LACP0422_RS04965	COG1418	mRNA catabolic process
LACP0422_RS04995	COG1253	flavin adenine dinucleotide binding
LACP0422_RS05000	COG1780	Probably involved in ribonucleotide reductase function
LACP0422_RS05005	COG0025	NhaP-type Na H and K H
LACP0422_RS05010	COG2814	Major facilitator Superfamily
LACP0422_RS05015	COG0789	Transcriptional regulator
LACP0422_RS05020	COG0604	alcohol dehydrogenase
LACP0422_RS05030	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
LACP0422_RS05035	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LACP0422_RS05040	COG0436	Aminotransferase
LACP0422_RS05055	COG0583	DNA-binding transcription factor activity
LACP0422_RS05060	COG0702	epimerase
LACP0422_RS05070	COG1074	ATP-dependent DNA helicase activity
LACP0422_RS05075	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
LACP0422_RS05085	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
LACP0422_RS05090	COG0284	orotidine-5'-phosphate decarboxylase activity
LACP0422_RS05095	COG0167	dihydroorotate dehydrogenase activity
LACP0422_RS05100	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
LACP0422_RS05105	COG0505	Belongs to the CarA family
LACP0422_RS05110	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
LACP0422_RS05115	COG0540	Belongs to the ATCase OTCase family
LACP0422_RS05120	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
LACP0422_RS05125	COG2508	Transcriptional regulator
LACP0422_RS05130	COG2233	PERMEase
LACP0422_RS05135	COG2252	PERMEase
LACP0422_RS05155	COG1215	transferase activity, transferring glycosyl groups
LACP0422_RS05165	COG0151	Belongs to the GarS family
LACP0422_RS05170	COG0138	bifunctional purine biosynthesis protein purh
LACP0422_RS05175	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
LACP0422_RS05180	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
LACP0422_RS05190	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
LACP0422_RS05195	COG0047	phosphoribosylformylglycinamidine synthase activity
LACP0422_RS05200	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
LACP0422_RS05205	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
LACP0422_RS05210	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
LACP0422_RS05220	COG1053	succinate dehydrogenase
LACP0422_RS05220	COG3976	FMN-binding domain protein
LACP0422_RS05220	COG0431	NADPH-dependent FMN reductase
LACP0422_RS05225	COG0431	NADPH-dependent FMN reductase
LACP0422_RS05225	COG1053	succinate dehydrogenase
LACP0422_RS05225	COG3976	FMN-binding domain protein
LACP0422_RS05230	COG0095	Lipoate-protein ligase
LACP0422_RS05235	COG2365	Tyrosine phosphatase family
LACP0422_RS05255	COG1136	(ABC) transporter
LACP0422_RS05270	COG1725	Transcriptional regulator
LACP0422_RS05275	COG1131	(ABC) transporter
LACP0422_RS05285	COG0589	response to stress
LACP0422_RS05295	COG2246	polysaccharide biosynthetic process
LACP0422_RS05310	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
LACP0422_RS05330	COG0366	Alpha amylase catalytic
LACP0422_RS05340	COG0561	phosphatase activity
LACP0422_RS05350	COG0110	maltose O-acetyltransferase activity
LACP0422_RS05355	COG0494	nUDIX hydrolase
LACP0422_RS05390	COG1827	regulation of RNA biosynthetic process
LACP0422_RS05395	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
LACP0422_RS05400	COG1309	transcriptional regulator
LACP0422_RS05410	COG1131	(ABC) transporter
LACP0422_RS05415	COG3048	D-serine ammonia-lyase activity
LACP0422_RS05420	COG2723	6-phospho-beta-galactosidase activity
LACP0422_RS05425	COG2723	6-phospho-beta-galactosidase activity
LACP0422_RS05430	COG1447	Phosphotransferase system cellobiose-specific component IIA
LACP0422_RS05435	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
LACP0422_RS05440	COG2188	Transcriptional regulator
LACP0422_RS05445	COG1216	Glycosyl transferase, family 2
LACP0422_RS05460	COG0561	phosphatase activity
LACP0422_RS05465	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
LACP0422_RS05490	COG0716	FMN binding
LACP0422_RS05510	COG0710	3-dehydroquinate dehydratase activity
LACP0422_RS05515	COG0531	amino acid
LACP0422_RS05560	COG4720	Psort location CytoplasmicMembrane, score
LACP0422_RS05565	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
LACP0422_RS05580	COG4990	cell redox homeostasis
LACP0422_RS05595	COG1811	Na channel or pump
LACP0422_RS05600	COG4978	Transcriptional regulator
LACP0422_RS05600	COG0789	Transcriptional regulator
LACP0422_RS05615	COG0577	efflux transmembrane transporter activity
LACP0422_RS05620	COG1136	(ABC) transporter
LACP0422_RS05660	COG2814	Major facilitator Superfamily
LACP0422_RS05670	COG2814	Major facilitator Superfamily
LACP0422_RS05680	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LACP0422_RS05685	COG2855	membrane
LACP0422_RS05690	COG0583	DNA-binding transcription factor activity
LACP0422_RS05700	COG0438	transferase activity, transferring glycosyl groups
LACP0422_RS05715	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
LACP0422_RS05720	COG4152	abc transporter atp-binding protein
LACP0422_RS05730	COG4221	oxidoreductase activity
LACP0422_RS05745	COG0789	Transcriptional regulator
LACP0422_RS05770	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
LACP0422_RS05790	COG0456	acetyltransferase
LACP0422_RS05815	COG0583	DNA-binding transcription factor activity
LACP0422_RS05825	COG1063	alcohol dehydrogenase
LACP0422_RS05830	COG1028	Short-chain dehydrogenase reductase Sdr
LACP0422_RS05835	COG0656	L-ascorbic acid biosynthetic process
LACP0422_RS05855	COG4975	Glucose uptake
LACP0422_RS05865	COG0656	L-ascorbic acid biosynthetic process
LACP0422_RS05870	COG0583	DNA-binding transcription factor activity
LACP0422_RS05890	COG4221	oxidoreductase activity
LACP0422_RS05895	COG0656	L-ascorbic acid biosynthetic process
LACP0422_RS05915	COG0589	response to stress
LACP0422_RS05920	COG0110	maltose O-acetyltransferase activity
LACP0422_RS05925	COG1011	Hydrolase
LACP0422_RS05940	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
LACP0422_RS05950	COG0667	Aldo Keto reductase
LACP0422_RS05955	COG1132	(ABC) transporter
LACP0422_RS05960	COG1132	(ABC) transporter
LACP0422_RS05965	COG2814	Major facilitator Superfamily
LACP0422_RS05975	COG1511	domain protein
LACP0422_RS05975	COG1511	domain protein
LACP0422_RS05985	COG0640	Transcriptional regulator
LACP0422_RS06010	COG0488	(ABC) transporter
LACP0422_RS06015	COG0561	phosphatase activity
LACP0422_RS06025	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
LACP0422_RS06040	COG2270	Major facilitator Superfamily
LACP0422_RS06090	COG1328	CTP reductase activity
LACP0422_RS06100	COG0242	peptide deformylase activity
LACP0422_RS06110	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
LACP0422_RS06125	COG0583	DNA-binding transcription factor activity
LACP0422_RS06135	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
LACP0422_RS06180	COG0697	spore germination
LACP0422_RS06205	COG1940	carbohydrate kinase activity
LACP0422_RS06210	COG1132	(ABC) transporter
LACP0422_RS06220	COG0778	Nitroreductase
LACP0422_RS06225	COG1263	PTS System
LACP0422_RS06225	COG2190	(PTS) system
LACP0422_RS06225	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LACP0422_RS06230	COG1116	anion transmembrane transporter activity
LACP0422_RS06235	COG4120	Belongs to the binding-protein-dependent transport system permease family
LACP0422_RS06265	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
LACP0422_RS06265	COG0617	tRNA 3'-terminal CCA addition
LACP0422_RS06265	COG3620	sequence-specific DNA binding
LACP0422_RS06270	COG0410	ABC transporter
LACP0422_RS06285	COG0559	Belongs to the binding-protein-dependent transport system permease family
LACP0422_RS06300	COG5549	protein import
LACP0422_RS06300	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LACP0422_RS06305	COG2246	polysaccharide biosynthetic process
LACP0422_RS06315	COG1914	H( )-stimulated, divalent metal cation uptake system
LACP0422_RS06335	COG0640	Transcriptional regulator
LACP0422_RS06345	COG1136	(ABC) transporter
LACP0422_RS06345	COG0577	efflux transmembrane transporter activity
LACP0422_RS06380	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
LACP0422_RS06385	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
LACP0422_RS06390	COG2723	6-phospho-beta-galactosidase activity
LACP0422_RS06400	COG0789	Transcriptional regulator
LACP0422_RS06405	COG0741	lytic transglycosylase activity
LACP0422_RS06425	COG0803	Belongs to the bacterial solute-binding protein 9 family
LACP0422_RS06450	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
LACP0422_RS06465	COG4221	oxidoreductase activity
LACP0422_RS06510	COG1132	(ABC) transporter
LACP0422_RS06515	COG1132	(ABC) transporter
LACP0422_RS06525	COG1473	amidohydrolase
LACP0422_RS06530	COG1028	Short-chain dehydrogenase reductase Sdr
LACP0422_RS06550	COG0531	amino acid
LACP0422_RS06570	COG2217	Heavy metal translocating P-type atpase
LACP0422_RS06625	COG1063	alcohol dehydrogenase
LACP0422_RS06665	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
LACP0422_RS06670	COG1733	regulation of RNA biosynthetic process
LACP0422_RS06675	COG2814	Major facilitator Superfamily
LACP0422_RS06685	COG0367	asparagine synthase
LACP0422_RS06690	COG3279	Response regulator of the LytR AlgR family
LACP0422_RS06700	COG1309	transcriptional regulator
LACP0422_RS06710	COG1012	belongs to the aldehyde dehydrogenase family
LACP0422_RS06725	COG1733	regulation of RNA biosynthetic process
LACP0422_RS06730	COG0300	oxidoreductase activity
LACP0422_RS06750	COG4989	oxidoreductase activity
LACP0422_RS06755	COG0477	Major facilitator Superfamily
LACP0422_RS06765	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
LACP0422_RS06770	COG1120	ATPase activity
LACP0422_RS06775	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LACP0422_RS06780	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LACP0422_RS06785	COG1309	transcriptional regulator
LACP0422_RS06795	COG4221	oxidoreductase activity
LACP0422_RS06800	COG0110	maltose O-acetyltransferase activity
LACP0422_RS06805	COG1028	Short-chain dehydrogenase reductase Sdr
LACP0422_RS06840	COG0481	GTPase activity
LACP0422_RS06850	COG2816	NAD+ diphosphatase activity
LACP0422_RS06860	COG1053	succinate dehydrogenase
LACP0422_RS06870	COG0783	Belongs to the Dps family
LACP0422_RS06880	COG2723	6-phospho-beta-galactosidase activity
LACP0422_RS06885	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
LACP0422_RS06900	COG0789	Transcriptional regulator
LACP0422_RS06920	COG0693	protein deglycase activity
LACP0422_RS06935	COG0577	efflux transmembrane transporter activity
LACP0422_RS06935	COG1136	(ABC) transporter
LACP0422_RS06945	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
LACP0422_RS06965	COG0656	L-ascorbic acid biosynthetic process
LACP0422_RS06980	COG0477	Major facilitator Superfamily
LACP0422_RS07010	COG0588	phosphoglycerate mutase activity
LACP0422_RS07015	COG0628	permease
LACP0422_RS07020	COG1940	carbohydrate kinase activity
LACP0422_RS07020	COG1846	Transcriptional regulator
LACP0422_RS07030	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
LACP0422_RS07040	COG2815	serine threonine protein kinase
LACP0422_RS07040	COG0515	serine threonine protein kinase
LACP0422_RS07075	COG1247	-acetyltransferase
LACP0422_RS07080	COG1686	Belongs to the peptidase S11 family
LACP0422_RS07100	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
LACP0422_RS07105	COG0516	GMP reductase activity
LACP0422_RS07105	COG0517	IMP dehydrogenase activity
LACP0422_RS07115	COG0012	GTP binding
LACP0422_RS07120	COG4481	Protein conserved in bacteria
LACP0422_RS07125	COG1475	DNA binding
LACP0422_RS07130	COG1192	Involved in chromosome partitioning
LACP0422_RS07140	COG0357	Ribosomal RNA small subunit methyltransferase G
LACP0422_RS07145	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
LACP0422_RS07160	COG0583	DNA-binding transcription factor activity
LACP0422_RS07165	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LACP0422_RS07170	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LACP0422_RS07175	COG0765	amino acid transport
LACP0422_RS07180	COG1126	abc transporter atp-binding protein
LACP0422_RS07185	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LACP0422_RS07210	COG1263	PTS System
LACP0422_RS07210	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LACP0422_RS07210	COG2190	(PTS) system
LACP0422_RS07215	COG0366	Alpha amylase catalytic
LACP0422_RS07220	COG1609	Transcriptional regulator
LACP0422_RS07230	COG0390	transport system, permease component
LACP0422_RS07235	COG4619	ABC transporter
LACP0422_RS07240	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
LACP0422_RS07255	COG0561	phosphatase activity
LACP0422_RS07265	COG0383	alpha-mannosidase activity
LACP0422_RS07270	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
LACP0422_RS07270	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LACP0422_RS07270	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LACP0422_RS07275	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LACP0422_RS07280	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LACP0422_RS07280	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LACP0422_RS07280	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
LACP0422_RS07285	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
LACP0422_RS07285	COG3711	transcriptional antiterminator
LACP0422_RS07300	COG1263	PTS System
LACP0422_RS07300	COG2190	(PTS) system
LACP0422_RS07300	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LACP0422_RS07330	COG0735	belongs to the Fur family
LACP0422_RS07355	COG1380	Effector of murein hydrolase LrgA
LACP0422_RS07365	COG1307	EDD domain protein, DegV family
LACP0422_RS07375	COG2738	Putative neutral zinc metallopeptidase
LACP0422_RS07590	COG1396	sequence-specific DNA binding
LACP0422_RS07600	COG2176	DNA-directed DNA polymerase activity
LACP0422_RS07645	COG1233	COG1233 Phytoene dehydrogenase and related
LACP0422_RS07650	COG1562	ergosterol biosynthetic process
LACP0422_RS07660	COG1929	Belongs to the glycerate kinase type-1 family
LACP0422_RS07675	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
LACP0422_RS07680	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
LACP0422_RS07685	COG0516	GMP reductase activity
LACP0422_RS07690	COG2365	Tyrosine phosphatase family
LACP0422_RS07695	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LACP0422_RS07710	COG0531	amino acid
LACP0422_RS07715	COG3158	transport of potassium into the cell
LACP0422_RS07720	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
LACP0422_RS07725	COG0628	permease
LACP0422_RS07730	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
LACP0422_RS07745	COG1272	protein, Hemolysin III
LACP0422_RS07750	COG0640	Transcriptional regulator
LACP0422_RS07785	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
LACP0422_RS07790	COG0285	dihydrofolate synthase activity
LACP0422_RS07795	COG0302	gtp cyclohydrolase
LACP0422_RS07800	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
LACP0422_RS07820	COG0803	Belongs to the bacterial solute-binding protein 9 family
LACP0422_RS07825	COG2814	Major facilitator Superfamily
LACP0422_RS07855	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
LACP0422_RS07860	COG1882	Formate acetyltransferase
LACP0422_RS07865	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
LACP0422_RS07875	COG2151	metal-sulfur cluster biosynthetic enzyme
LACP0422_RS07880	COG4989	oxidoreductase activity
LACP0422_RS07910	COG2217	Heavy metal translocating P-type atpase
LACP0422_RS07920	COG2315	Protein conserved in bacteria
LACP0422_RS07930	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
LACP0422_RS07935	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
LACP0422_RS07950	COG1757	Na H antiporter
LACP0422_RS07955	COG1113	amino acid transport
LACP0422_RS07965	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
LACP0422_RS07980	COG1393	Belongs to the ArsC family
LACP0422_RS07985	COG3189	MarR family transcriptional regulator
LACP0422_RS07995	COG1194	a g-specific adenine glycosylase
LACP0422_RS08010	COG0071	Belongs to the small heat shock protein (HSP20) family
LACP0422_RS08035	COG0697	spore germination
LACP0422_RS08050	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
LACP0422_RS08075	COG0477	Major facilitator Superfamily
LACP0422_RS08125	COG0737	Belongs to the 5'-nucleotidase family
LACP0422_RS08135	COG0656	L-ascorbic acid biosynthetic process
LACP0422_RS08155	COG1968	undecaprenyl-diphosphatase activity
LACP0422_RS08160	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
LACP0422_RS08195	COG2207	Transcriptional regulator
LACP0422_RS08220	COG0076	glutamate decarboxylase activity
LACP0422_RS08270	COG2226	methyltransferase
LACP0422_RS08285	COG2217	Heavy metal translocating P-type atpase
LACP0422_RS08290	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
LACP0422_RS08295	COG3118	belongs to the thioredoxin family
LACP0422_RS08300	COG1937	Protein conserved in bacteria
LACP0422_RS08320	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
LACP0422_RS08325	COG3590	peptidase
LACP0422_RS08340	COG0446	pyridine nucleotide-disulphide oxidoreductase
LACP0422_RS08390	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
LACP0422_RS08400	COG1114	Component of the transport system for branched-chain amino acids
LACP0422_RS08410	COG1874	Beta-galactosidase
LACP0422_RS08415	COG1609	Transcriptional regulator
LACP0422_RS08425	COG0477	Major facilitator Superfamily
LACP0422_RS08445	COG2184	nucleotidyltransferase activity
LACP0422_RS08450	COG2944	sequence-specific DNA binding
LACP0422_RS08455	COG1609	Transcriptional regulator
LACP0422_RS08460	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
LACP0422_RS08465	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
LACP0422_RS08470	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
LACP0422_RS08490	COG2211	Major facilitator Superfamily
LACP0422_RS08490	COG2190	(PTS) system
LACP0422_RS08495	COG2017	converts alpha-aldose to the beta-anomer
LACP0422_RS08500	COG1609	Transcriptional regulator
LACP0422_RS08505	COG0667	Aldo Keto reductase
LACP0422_RS08525	COG0710	3-dehydroquinate dehydratase activity
LACP0422_RS08530	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
LACP0422_RS08535	COG0583	DNA-binding transcription factor activity
LACP0422_RS08540	COG2271	Major facilitator Superfamily
LACP0422_RS08555	COG1028	Short-chain dehydrogenase reductase Sdr
LACP0422_RS08570	COG2271	Major facilitator Superfamily
LACP0422_RS08580	COG2267	carboxylic ester hydrolase activity
LACP0422_RS08585	COG2188	Transcriptional regulator
LACP0422_RS08590	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
LACP0422_RS08595	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
LACP0422_RS08600	COG2971	BadF BadG BcrA BcrD
LACP0422_RS08610	COG2723	6-phospho-beta-galactosidase activity
LACP0422_RS08620	COG3711	transcriptional antiterminator
LACP0422_RS08625	COG2723	6-phospho-beta-galactosidase activity
LACP0422_RS08630	COG2723	6-phospho-beta-galactosidase activity
LACP0422_RS08635	COG2190	(PTS) system
LACP0422_RS08635	COG1263	PTS System
LACP0422_RS08635	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LACP0422_RS08670	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
LACP0422_RS08685	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
LACP0422_RS08705	COG3711	transcriptional antiterminator
LACP0422_RS08720	COG3775	system Galactitol-specific IIC component
LACP0422_RS08725	COG3414	Phosphotransferase system galactitol-specific IIB component
LACP0422_RS08735	COG1349	DNA-binding transcription factor activity
LACP0422_RS08740	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
LACP0422_RS08750	COG0110	maltose O-acetyltransferase activity
LACP0422_RS08755	COG2160	L-arabinose isomerase activity
LACP0422_RS08775	COG1609	Transcriptional regulator
LACP0422_RS08780	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
LACP0422_RS08800	COG2261	transglycosylase associated protein
LACP0422_RS08810	COG1393	Belongs to the ArsC family
LACP0422_RS08830	COG4512	PFAM Accessory gene regulator B
LACP0422_RS08845	COG1304	FMN binding
LACP0422_RS08850	COG0028	Belongs to the TPP enzyme family
LACP0422_RS08855	COG1959	2 iron, 2 sulfur cluster binding
LACP0422_RS08860	COG0028	Belongs to the TPP enzyme family
LACP0422_RS08875	COG0235	Class ii aldolase
LACP0422_RS08880	COG4806	L-rhamnose isomerase
LACP0422_RS08885	COG3254	rhamnose metabolic process
LACP0422_RS08890	COG1070	Carbohydrate kinase
LACP0422_RS08895	COG2814	Major facilitator Superfamily
LACP0422_RS08900	COG2207	Transcriptional regulator
LACP0422_RS08905	COG1349	DNA-binding transcription factor activity
LACP0422_RS09020	COG1940	carbohydrate kinase activity
LACP0422_RS09025	COG0383	alpha-mannosidase activity
LACP0422_RS09035	COG2188	Transcriptional regulator
LACP0422_RS09045	COG3842	ATPase activity
LACP0422_RS09055	COG4753	response regulator
LACP0422_RS09055	COG2207	Transcriptional regulator
LACP0422_RS09060	COG2972	Histidine kinase
LACP0422_RS09070	COG0366	Alpha amylase catalytic
LACP0422_RS09075	COG1653	transport
LACP0422_RS09080	COG0395	ABC-type sugar transport system, permease component
LACP0422_RS09095	COG2207	Transcriptional regulator
LACP0422_RS09095	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
LACP0422_RS09100	COG1132	(ABC) transporter
LACP0422_RS09105	COG1132	(ABC) transporter
LACP0422_RS09110	COG2188	Transcriptional regulator
LACP0422_RS09125	COG3732	PTS system glucitol sorbitol-specific
LACP0422_RS09130	COG3730	PTS system glucitol sorbitol-specific
LACP0422_RS09150	COG4975	Glucose uptake
LACP0422_RS09155	COG1869	D-ribose catabolic process
LACP0422_RS09165	COG1609	Transcriptional regulator
LACP0422_RS09170	COG1454	alcohol dehydrogenase
LACP0422_RS09170	COG1012	belongs to the aldehyde dehydrogenase family
LACP0422_RS09180	COG1695	Transcriptional regulator
LACP0422_RS09185	COG3479	Phenolic acid decarboxylase
LACP0422_RS09200	COG1307	EDD domain protein, DegV family
LACP0422_RS09240	COG0445	tRNA wobble uridine modification
LACP0422_RS09245	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
LACP0422_RS09250	COG1847	R3H domain protein
LACP0422_RS09260	COG4166	transmembrane transport
LACP0422_RS09265	COG0706	membrane insertase activity
LACP0422_RS09270	COG0594	ribonuclease P activity
LACP0422_RS09275	COG0230	Belongs to the bacterial ribosomal protein bL34 family
LACP0422_RS09280	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
LACP0422_RS09285	COG0592	DNA-directed DNA polymerase activity
LACP0422_RS09290	COG2501	S4 domain
LACP0422_RS09295	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
LACP0422_RS09300	COG0187	DNA topoisomerase II activity
LACP0422_RS09315	COG0360	Binds together with S18 to 16S ribosomal RNA
LACP0422_RS09320	COG0629	single-stranded DNA binding
LACP0422_RS09325	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
LACP0422_RS09335	COG0359	binds to the 23S rRNA
LACP0422_RS09340	COG0305	Participates in initiation and elongation during chromosome replication
LACP0422_RS09345	COG2814	Major facilitator Superfamily
LACP0422_RS09350	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
LACP0422_RS09355	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
LACP0422_RS09360	COG4166	transmembrane transport
LACP0422_RS09365	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
LACP0422_RS09370	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
LACP0422_RS09375	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
LACP0422_RS09380	COG0297	glycogen (starch) synthase activity
LACP0422_RS09385	COG0058	SHG alpha-glucan phosphorylase activity
LACP0422_RS09390	COG0366	Alpha amylase catalytic
LACP0422_RS09390	COG3103	Sh3 type 3 domain protein
LACP0422_RS09400	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
LACP0422_RS09405	COG1554	hydrolase, family 65, central catalytic
LACP0422_RS09415	COG1278	Cold shock
LACP0422_RS09430	COG0745	RESPONSE REGULATOR receiver
LACP0422_RS09435	COG5002	protein histidine kinase activity
LACP0422_RS09445	COG4853	Protein conserved in bacteria
LACP0422_RS09450	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
LACP0422_RS09455	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LACP0422_RS09460	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
LACP0422_RS09470	COG1012	belongs to the aldehyde dehydrogenase family
LACP0422_RS09475	COG1573	uracil-dna glycosylase
LACP0422_RS09495	COG1053	succinate dehydrogenase
LACP0422_RS09495	COG0431	NADPH-dependent FMN reductase
LACP0422_RS09495	COG3976	FMN-binding domain protein
LACP0422_RS09500	COG0471	metal ion transport
LACP0422_RS09515	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
LACP0422_RS09520	COG1028	Short-chain dehydrogenase reductase Sdr
LACP0422_RS09530	COG0778	Nitroreductase
LACP0422_RS09535	COG2508	Transcriptional regulator
LACP0422_RS09540	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
LACP0422_RS09545	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
LACP0422_RS09555	COG2365	Tyrosine phosphatase family
LACP0422_RS09560	COG2368	4-hydroxyphenylacetate
LACP0422_RS09580	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
LACP0422_RS09615	COG0604	alcohol dehydrogenase
LACP0422_RS09635	COG2267	carboxylic ester hydrolase activity
LACP0422_RS09640	COG3022	response to hydroperoxide
LACP0422_RS09650	COG4166	transmembrane transport
LACP0422_RS09675	COG1122	ATPase activity
LACP0422_RS09680	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
LACP0422_RS09685	COG0310	cobalt ion transport
LACP0422_RS09690	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
LACP0422_RS09695	COG3875	lactate racemase activity
LACP0422_RS09700	COG1691	(AIR) carboxylase
LACP0422_RS09705	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
LACP0422_RS09710	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
LACP0422_RS09715	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
LACP0422_RS09720	COG1606	tRNA processing
LACP0422_RS09730	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
LACP0422_RS09735	COG0351	phosphomethylpyrimidine kinase
LACP0422_RS09740	COG0352	thiamine-phosphate diphosphorylase activity
LACP0422_RS09750	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
LACP0422_RS09765	COG1113	amino acid transport
LACP0422_RS09775	COG2267	carboxylic ester hydrolase activity
LACP0422_RS09780	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
LACP0422_RS09790	COG1983	PspC domain protein
LACP0422_RS09830	COG2807	transmembrane transport
LACP0422_RS09835	COG0656	L-ascorbic acid biosynthetic process
LACP0422_RS09840	COG0667	Aldo Keto reductase
LACP0422_RS09870	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
LACP0422_RS09875	COG1122	ATPase activity
LACP0422_RS09880	COG4720	Psort location CytoplasmicMembrane, score
LACP0422_RS09890	COG2188	Transcriptional regulator
LACP0422_RS09915	COG1028	Short-chain dehydrogenase reductase Sdr
LACP0422_RS09920	COG1131	(ABC) transporter
LACP0422_RS09935	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
LACP0422_RS09940	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
LACP0422_RS09945	COG1309	transcriptional regulator
LACP0422_RS09950	COG2376	Dihydroxyacetone kinase
LACP0422_RS09955	COG2376	Dihydroxyacetone kinase
LACP0422_RS09960	COG1461	Dihydroxyacetone kinase
LACP0422_RS09965	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
LACP0422_RS09970	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
LACP0422_RS09975	COG1609	Transcriptional regulator
LACP0422_RS09980	COG1609	Transcriptional regulator
LACP0422_RS09985	COG0366	Alpha amylase catalytic
LACP0422_RS09990	COG2182	Extracellular solute-binding protein
LACP0422_RS09995	COG1175	transmembrane transport
LACP0422_RS10000	COG3833	ABC-type maltose transport systems, permease component
LACP0422_RS10010	COG0366	Alpha amylase catalytic
LACP0422_RS10015	COG3842	ATPase activity
LACP0422_RS10065	COG1757	Na H antiporter
LACP0422_RS10090	COG4166	transmembrane transport
LACP0422_RS10095	COG4166	transmembrane transport
LACP0422_RS10105	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
LACP0422_RS10110	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
LACP0422_RS10115	COG0406	alpha-ribazole phosphatase activity
LACP0422_RS10120	COG0667	Aldo Keto reductase
LACP0422_RS10150	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
LACP0422_RS10155	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
LACP0422_RS10160	COG0488	(ABC) transporter
LACP0422_RS10170	COG4172	Belongs to the ABC transporter superfamily
LACP0422_RS10180	COG0386	Belongs to the glutathione peroxidase family
LACP0422_RS10190	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
LACP0422_RS10205	COG0363	glucosamine-6-phosphate deaminase activity
LACP0422_RS10215	COG1053	succinate dehydrogenase
LACP0422_RS10230	COG2213	PTS system mannitol-specific
LACP0422_RS10240	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
LACP0422_RS10245	COG0246	Mannitol dehydrogenase
LACP0422_RS10255	COG3118	belongs to the thioredoxin family
LACP0422_RS10280	COG0431	NADPH-dependent FMN reductase
LACP0422_RS10285	COG2188	Transcriptional regulator
LACP0422_RS10290	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
LACP0422_RS10305	COG3964	amidohydrolase
LACP0422_RS10325	COG1045	serine acetyltransferase
LACP0422_RS10330	COG0626	cystathionine gamma-synthase activity
LACP0422_RS10335	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
LACP0422_RS10360	COG2188	Transcriptional regulator
LACP0422_RS10365	COG0366	Alpha amylase catalytic
LACP0422_RS10370	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LACP0422_RS10370	COG2190	(PTS) system
LACP0422_RS10370	COG1263	PTS System
LACP0422_RS10375	COG2190	(PTS) system
LACP0422_RS10375	COG1263	PTS System
LACP0422_RS10375	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LACP0422_RS10385	COG0163	prenyltransferase activity
LACP0422_RS10395	COG1959	2 iron, 2 sulfur cluster binding
LACP0422_RS10400	COG1309	transcriptional regulator
LACP0422_RS10405	COG1914	H( )-stimulated, divalent metal cation uptake system
LACP0422_RS10425	COG2814	Major facilitator Superfamily
LACP0422_RS10435	COG5002	protein histidine kinase activity
LACP0422_RS10440	COG0745	RESPONSE REGULATOR receiver
LACP0422_RS10450	COG1737	Transcriptional regulator
LACP0422_RS10455	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
LACP0422_RS10470	COG1316	TRANSCRIPTIONal
LACP0422_RS10475	COG0277	FAD linked oxidase domain protein
LACP0422_RS10485	COG2357	RelA SpoT domain protein
LACP0422_RS10495	COG1033	growth of symbiont in host cell
LACP0422_RS10495	COG2409	Drug exporters of the RND superfamily
LACP0422_RS10500	COG2818	Glycosylase
LACP0422_RS10510	COG0577	efflux transmembrane transporter activity
LACP0422_RS10515	COG1136	(ABC) transporter
LACP0422_RS10530	COG0741	lytic transglycosylase activity
LACP0422_RS10535	COG3942	CHAP domain
LACP0422_RS10535	COG1388	LysM domain
LACP0422_RS10565	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
LACP0422_RS10575	COG1846	Transcriptional regulator
LACP0422_RS10580	COG1252	NADH dehydrogenase
LACP0422_RS10620	COG3842	ATPase activity
LACP0422_RS10650	COG1725	Transcriptional regulator
LACP0422_RS10655	COG1131	(ABC) transporter
LACP0422_RS10665	COG1012	belongs to the aldehyde dehydrogenase family
LACP0422_RS10665	COG1454	alcohol dehydrogenase
LACP0422_RS10705	COG1268	BioY protein
LACP0422_RS10720	COG0436	Aminotransferase
LACP0422_RS10730	COG1682	transport, permease protein
LACP0422_RS10735	COG1134	teichoic acid transport
LACP0422_RS10750	COG2814	Major facilitator Superfamily
LACP0422_RS10755	COG0004	ammonium transporteR
LACP0422_RS10775	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
LACP0422_RS10785	COG3759	membrane
LACP0422_RS10790	COG1881	PFAM PEBP family protein
LACP0422_RS10820	COG0300	oxidoreductase activity
LACP0422_RS10825	COG0328	RNA-DNA hybrid ribonuclease activity
LACP0422_RS10835	COG1125	glycine betaine transport
LACP0422_RS10845	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
LACP0422_RS10855	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
LACP0422_RS10940	COG0110	maltose O-acetyltransferase activity
LACP0422_RS10950	COG0561	phosphatase activity
LACP0422_RS10960	COG0561	phosphatase activity
LACP0422_RS10965	COG1114	Component of the transport system for branched-chain amino acids
LACP0422_RS11005	COG0463	Glycosyl transferase, family 2
LACP0422_RS11025	COG3279	Response regulator of the LytR AlgR family
LACP0422_RS11050	COG2274	protein secretion by the type I secretion system
LACP0422_RS11085	COG3973	AAA domain
LACP0422_RS11090	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
LACP0422_RS11095	COG0180	Tryptophanyl-tRNA synthetase
LACP0422_RS11100	COG2188	Transcriptional regulator
LACP0422_RS11105	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
LACP0422_RS11120	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
LACP0422_RS11125	COG2723	6-phospho-beta-galactosidase activity
LACP0422_RS11130	COG1940	carbohydrate kinase activity
LACP0422_RS11140	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
LACP0422_RS11155	COG0248	Ppx GppA phosphatase
LACP0422_RS11170	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
LACP0422_RS11175	COG1801	Protein of unknown function DUF72
LACP0422_RS11185	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LACP0422_RS11185	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LACP0422_RS11190	COG2814	Major facilitator Superfamily
LACP0422_RS11195	COG0084	hydrolase, TatD family'
LACP0422_RS11200	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
LACP0422_RS11205	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
LACP0422_RS11210	COG4466	Protein conserved in bacteria
LACP0422_RS11215	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
LACP0422_RS11225	COG1073	alpha beta
LACP0422_RS11230	COG1121	(ABC) transporter
LACP0422_RS11235	COG1321	iron dependent repressor
LACP0422_RS11235	COG1108	ABC-type Mn2 Zn2 transport systems permease components
LACP0422_RS11260	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
LACP0422_RS11265	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
LACP0422_RS11275	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
LACP0422_RS11295	COG1078	dGTPase activity
LACP0422_RS11300	COG0095	Lipoate-protein ligase
LACP0422_RS11310	COG3343	RNA polymerase activity
LACP0422_RS11315	COG0504	CTP synthase activity
LACP0422_RS11320	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
LACP0422_RS11325	COG0814	amino acid
LACP0422_RS11330	COG1760	l-serine dehydratase
LACP0422_RS11335	COG1760	l-serine dehydratase
LACP0422_RS11350	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
LACP0422_RS11355	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
LACP0422_RS11360	COG0254	rRNA binding
LACP0422_RS11370	COG3764	Sortase (surface protein transpeptidase)
LACP0422_RS11375	COG1704	LemA family
LACP0422_RS11380	COG0501	Belongs to the peptidase M48B family
LACP0422_RS11390	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
LACP0422_RS11400	COG0736	holo-[acyl-carrier-protein] synthase activity
LACP0422_RS11405	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
LACP0422_RS11410	COG2337	Toxic component of a toxin-antitoxin (TA) module
LACP0422_RS11415	COG3158	transport of potassium into the cell
LACP0422_RS11435	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
LACP0422_RS11440	COG0505	Belongs to the CarA family
LACP0422_RS11445	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
LACP0422_RS11450	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
LACP0422_RS11455	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
LACP0422_RS11460	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
LACP0422_RS11465	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
LACP0422_RS11480	COG2267	carboxylic ester hydrolase activity
LACP0422_RS11495	COG0039	L-malate dehydrogenase activity
LACP0422_RS11500	COG0193	aminoacyl-tRNA hydrolase activity
LACP0422_RS11505	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
LACP0422_RS11510	COG2244	polysaccharide biosynthetic process
LACP0422_RS11515	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
LACP0422_RS11525	COG1098	S1 RNA binding domain
LACP0422_RS11530	COG0037	tRNA processing
LACP0422_RS11545	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
LACP0422_RS11550	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
LACP0422_RS11555	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
LACP0422_RS11595	COG3104	oligopeptide transport
LACP0422_RS11645	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
LACP0422_RS11655	COG2188	Transcriptional regulator
LACP0422_RS11665	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
LACP0422_RS11670	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
LACP0422_RS11685	COG2183	response to ionizing radiation
LACP0422_RS11690	COG3091	SprT-like family
LACP0422_RS11695	COG0460	homoserine dehydrogenase
LACP0422_RS11700	COG0083	homoserine kinase activity
LACP0422_RS11720	COG3715	PTS system
LACP0422_RS11725	COG3716	PTS system mannose fructose sorbose family IID component
LACP0422_RS11735	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
LACP0422_RS11735	COG3933	PFAM sigma-54 factor interaction domain-containing protein
LACP0422_RS11740	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
LACP0422_RS11740	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LACP0422_RS11745	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LACP0422_RS11745	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
LACP0422_RS11750	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
LACP0422_RS11760	COG0439	Biotin carboxylase
LACP0422_RS11770	COG0825	malonyl-CoA metabolic process
LACP0422_RS11775	COG1316	TRANSCRIPTIONal
LACP0422_RS11785	COG0697	spore germination
LACP0422_RS11790	COG0588	phosphoglycerate mutase activity
LACP0422_RS11805	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
LACP0422_RS11815	COG0756	dUTP diphosphatase activity
LACP0422_RS11825	COG4956	integral membrane protein (PIN domain superfamily)
LACP0422_RS11830	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
LACP0422_RS11835	COG0215	cysteine-tRNA ligase activity
LACP0422_RS11840	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
LACP0422_RS11845	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LACP0422_RS11860	COG0267	Belongs to the bacterial ribosomal protein bL33 family
LACP0422_RS11870	COG0250	Participates in transcription elongation, termination and antitermination
LACP0422_RS11880	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
LACP0422_RS11885	COG0081	regulation of translation
LACP0422_RS11890	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
LACP0422_RS11895	COG0222	ribosome binding
LACP0422_RS11915	COG1611	Belongs to the LOG family
LACP0422_RS11925	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LACP0422_RS11930	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
LACP0422_RS11935	COG2813	Specifically methylates the guanine in position
LACP0422_RS11950	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
LACP0422_RS11955	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
LACP0422_RS11960	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
LACP0422_RS11970	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
LACP0422_RS11975	COG3870	Protein conserved in bacteria
LACP0422_RS11980	COG0470	DNA polymerase III
LACP0422_RS11985	COG4467	Involved in initiation control of chromosome replication
LACP0422_RS12000	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
LACP0422_RS12010	COG3639	organic phosphonate transmembrane transporter activity
LACP0422_RS12020	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
LACP0422_RS12030	COG1214	PFAM Peptidase M22, glycoprotease
LACP0422_RS12035	COG0456	acetyltransferase
LACP0422_RS12040	COG0456	acetyltransferase
LACP0422_RS12045	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
LACP0422_RS12050	COG0488	(ABC) transporter
LACP0422_RS12055	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
LACP0422_RS12065	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
LACP0422_RS12070	COG0459	protein refolding
LACP0422_RS12075	COG0531	amino acid
LACP0422_RS12085	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
LACP0422_RS12090	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
LACP0422_RS12095	COG1739	Uncharacterized protein family UPF0029
LACP0422_RS12100	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
LACP0422_RS12115	COG0653	protein targeting
LACP0422_RS12130	COG0745	RESPONSE REGULATOR receiver
LACP0422_RS12135	COG5002	protein histidine kinase activity
LACP0422_RS12140	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
LACP0422_RS12145	COG0573	inorganic phosphate transmembrane transporter activity
LACP0422_RS12150	COG0581	inorganic phosphate transmembrane transporter activity
LACP0422_RS12155	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
LACP0422_RS12160	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
LACP0422_RS12165	COG0704	Plays a role in the regulation of phosphate uptake
LACP0422_RS12170	COG1983	PspC domain protein
LACP0422_RS12175	COG1950	PFAM Membrane protein of
LACP0422_RS12180	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
LACP0422_RS12185	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
LACP0422_RS12190	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
LACP0422_RS12195	COG1210	Utp--glucose-1-phosphate uridylyltransferase
LACP0422_RS12205	COG0446	pyridine nucleotide-disulphide oxidoreductase
LACP0422_RS12225	COG1215	transferase activity, transferring glycosyl groups
LACP0422_RS12240	COG0492	ferredoxin-NADP+ reductase activity
LACP0422_RS12245	COG2323	membrane
LACP0422_RS12255	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
LACP0422_RS12265	COG0446	pyridine nucleotide-disulphide oxidoreductase
LACP0422_RS12275	COG2814	Major facilitator Superfamily
LACP0422_RS12285	COG0556	nucleotide-excision repair
LACP0422_RS12290	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
LACP0422_RS12295	COG1854	S-ribosylhomocysteine lyase activity
LACP0422_RS12300	COG0137	argininosuccinate synthase activity
LACP0422_RS12305	COG0165	Argininosuccinate lyase
LACP0422_RS12315	COG1660	Displays ATPase and GTPase activities
LACP0422_RS12325	COG1481	regulation of sporulation
LACP0422_RS12335	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LACP0422_RS12340	COG0740	serine-type endopeptidase activity
LACP0422_RS12350	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
LACP0422_RS12355	COG2390	Transcriptional regulator
LACP0422_RS12365	COG0126	phosphoglycerate kinase activity
LACP0422_RS12370	COG0149	triose-phosphate isomerase activity
LACP0422_RS12375	COG0148	phosphopyruvate hydratase activity
LACP0422_RS12385	COG0038	chloride channel
LACP0422_RS12390	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
LACP0422_RS12400	COG0557	exoribonuclease II activity
LACP0422_RS12405	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
LACP0422_RS12420	COG0765	amino acid transport
LACP0422_RS12425	COG1126	abc transporter atp-binding protein
LACP0422_RS12435	COG0561	phosphatase activity
LACP0422_RS12440	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
LACP0422_RS12445	COG0280	phosphate acetyltransferase
LACP0422_RS12450	COG0802	atpase or kinase
LACP0422_RS12465	COG0708	Exodeoxyribonuclease III
LACP0422_RS12475	COG0812	UDP-N-acetylmuramate dehydrogenase activity
LACP0422_RS12480	COG0025	NhaP-type Na H and K H
LACP0422_RS12505	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
LACP0422_RS12510	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
LACP0422_RS12520	COG0561	phosphatase activity
LACP0422_RS12530	COG2017	converts alpha-aldose to the beta-anomer
LACP0422_RS12545	COG0778	Nitroreductase
LACP0422_RS12560	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
LACP0422_RS12575	COG1393	Belongs to the ArsC family
LACP0422_RS12590	COG0477	Major facilitator Superfamily
LACP0422_RS12595	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
LACP0422_RS12595	COG0248	Ppx GppA phosphatase
LACP0422_RS12600	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
LACP0422_RS12610	COG3475	LICD family
LACP0422_RS12625	COG2252	PERMEase
LACP0422_RS12630	COG0028	Belongs to the TPP enzyme family
LACP0422_RS12635	COG0196	riboflavin kinase activity
LACP0422_RS12640	COG0028	Belongs to the TPP enzyme family
LACP0422_RS12645	COG2267	carboxylic ester hydrolase activity
LACP0422_RS12655	COG2755	lipolytic protein G-D-S-L family
LACP0422_RS12655	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
LACP0422_RS12660	COG2936	dipeptidyl-peptidase activity
LACP0422_RS12675	COG0531	amino acid
LACP0422_RS12700	COG0194	GDP metabolic process
LACP0422_RS12705	COG0735	belongs to the Fur family
LACP0422_RS12720	COG0546	phosphoglycolate phosphatase activity
LACP0422_RS12725	COG0436	Aminotransferase
LACP0422_RS12730	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LACP0422_RS12750	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LACP0422_RS12755	COG0765	amino acid transport
LACP0422_RS12760	COG0765	amino acid transport
LACP0422_RS12765	COG1263	PTS System
LACP0422_RS12765	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LACP0422_RS12765	COG2190	(PTS) system
LACP0422_RS12775	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LACP0422_RS12775	COG1263	PTS System
LACP0422_RS12780	COG3394	polysaccharide catabolic process
LACP0422_RS12785	COG0531	amino acid
LACP0422_RS12790	COG1846	Transcriptional regulator
LACP0422_RS12820	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
LACP0422_RS12830	COG2076	Multidrug Resistance protein
LACP0422_RS12845	COG0588	phosphoglycerate mutase activity
LACP0422_RS12850	COG0569	domain protein
LACP0422_RS12850	COG0475	glutathione-regulated potassium exporter activity
LACP0422_RS12855	COG0456	acetyltransferase
LACP0422_RS12855	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
LACP0422_RS12860	COG0586	Pfam SNARE associated Golgi protein
LACP0422_RS12865	COG3973	AAA domain
LACP0422_RS12870	COG2070	2-Nitropropane dioxygenase
LACP0422_RS12875	COG1072	(Pantothenic acid kinase))
LACP0422_RS12880	COG0518	GMP synthase (glutamine-hydrolyzing) activity
LACP0422_RS12880	COG0519	Catalyzes the synthesis of GMP from XMP
LACP0422_RS12885	COG0464	growth
LACP0422_RS12915	COG1396	sequence-specific DNA binding
LACP0422_RS12920	COG1266	CAAX protease self-immunity
LACP0422_RS12925	COG1733	regulation of RNA biosynthetic process
LACP0422_RS12930	COG2814	Major facilitator Superfamily
LACP0422_RS12945	COG2755	lipolytic protein G-D-S-L family
LACP0422_RS12945	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
LACP0422_RS12950	COG2261	transglycosylase associated protein
LACP0422_RS12965	COG1302	Protein conserved in bacteria
LACP0422_RS12995	COG0308	aminopeptidase N
LACP0422_RS13025	COG0572	uridine kinase
LACP0422_RS13040	COG0583	DNA-binding transcription factor activity
LACP0422_RS13045	COG1053	succinate dehydrogenase
LACP0422_RS13055	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
LACP0422_RS13060	COG0017	Asparaginyl-tRNA synthetase
LACP0422_RS13065	COG2502	aspartate--ammonia ligase
LACP0422_RS13070	COG4690	dipeptidase activity
LACP0422_RS13090	COG0514	ATP-dependent DNA helicase (RecQ)
LACP0422_RS13095	COG0564	pseudouridine synthase activity
LACP0422_RS13100	COG0640	Transcriptional regulator
LACP0422_RS13150	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
LACP0422_RS13155	COG0527	aspartate kinase activity
LACP0422_RS13160	COG0367	asparagine synthase
LACP0422_RS13190	COG2814	Major facilitator Superfamily
LACP0422_RS13210	COG1278	Cold shock
LACP0422_RS13215	COG2966	Psort location CytoplasmicMembrane, score
LACP0422_RS13225	COG1316	TRANSCRIPTIONal
LACP0422_RS13245	COG1959	2 iron, 2 sulfur cluster binding
LACP0422_RS13250	COG0028	Belongs to the TPP enzyme family
LACP0422_RS13255	COG0833	amino acid
LACP0422_RS13265	COG1428	Deoxynucleoside kinase
LACP0422_RS13270	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
LACP0422_RS13315	COG4463	regulation of RNA biosynthetic process
LACP0422_RS13320	COG0542	response to heat
LACP0422_RS13330	COG0085	RNA polymerase activity
LACP0422_RS13335	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
LACP0422_RS13340	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
LACP0422_RS13345	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
LACP0422_RS13350	COG0049	tRNA binding
LACP0422_RS13355	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
LACP0422_RS13360	COG0051	transcription antitermination factor activity, RNA binding
LACP0422_RS13365	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
LACP0422_RS13370	COG0088	Forms part of the polypeptide exit tunnel
LACP0422_RS13375	COG0089	rRNA binding
LACP0422_RS13380	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
LACP0422_RS13385	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
LACP0422_RS13390	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
LACP0422_RS13395	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
LACP0422_RS13400	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
LACP0422_RS13405	COG0255	Belongs to the universal ribosomal protein uL29 family
LACP0422_RS13410	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
LACP0422_RS13415	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
LACP0422_RS13420	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
LACP0422_RS13425	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
LACP0422_RS13430	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
LACP0422_RS13435	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
LACP0422_RS13440	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
LACP0422_RS13445	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
LACP0422_RS13450	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
LACP0422_RS13455	COG1841	ribosomal large subunit assembly
LACP0422_RS13460	COG0200	Binds to the 23S rRNA
LACP0422_RS13470	COG0563	adenylate kinase activity
LACP0422_RS13475	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
LACP0422_RS13480	COG0257	Belongs to the bacterial ribosomal protein bL36 family
LACP0422_RS13485	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
LACP0422_RS13490	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
LACP0422_RS13495	COG0202	RNA polymerase activity
LACP0422_RS13500	COG0203	ribosomal protein L17
LACP0422_RS13525	COG4939	FMN-binding domain protein
LACP0422_RS13535	COG1122	ATPase activity
LACP0422_RS13540	COG1122	ATPase activity
LACP0422_RS13550	COG0101	tRNA pseudouridine synthase activity
LACP0422_RS13555	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
LACP0422_RS13560	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
LACP0422_RS13580	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
LACP0422_RS13585	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
LACP0422_RS13590	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
LACP0422_RS13595	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
LACP0422_RS13600	COG0471	metal ion transport
LACP0422_RS13605	COG2151	metal-sulfur cluster biosynthetic enzyme
LACP0422_RS13610	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
LACP0422_RS13620	COG4977	sequence-specific DNA binding
LACP0422_RS13620	COG1917	Cupin 2, conserved barrel domain protein
LACP0422_RS13625	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
LACP0422_RS13630	COG1121	(ABC) transporter
LACP0422_RS13635	COG1108	ABC-type Mn2 Zn2 transport systems permease components
LACP0422_RS13640	COG0803	Belongs to the bacterial solute-binding protein 9 family
LACP0422_RS13650	COG0039	L-malate dehydrogenase activity
LACP0422_RS13655	COG0471	metal ion transport
LACP0422_RS13675	COG3052	prosthetic group binding
LACP0422_RS13695	COG0114	fumarate hydratase activity
LACP0422_RS13700	COG1053	succinate dehydrogenase
LACP0422_RS13710	COG0583	DNA-binding transcription factor activity
LACP0422_RS13715	COG0583	DNA-binding transcription factor activity
LACP0422_RS13720	COG0281	malic enzyme
LACP0422_RS13730	COG0531	amino acid
LACP0422_RS13735	COG4684	Psort location CytoplasmicMembrane, score
LACP0422_RS13750	COG1271	oxidase subunit
LACP0422_RS13755	COG1294	oxidase, subunit
LACP0422_RS13760	COG4988	ABC transporter
LACP0422_RS13765	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
LACP0422_RS13780	COG0142	geranyltranstransferase activity
LACP0422_RS13795	COG1705	Flagellar rod assembly protein muramidase FlgJ
LACP0422_RS13800	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
LACP0422_RS13805	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
LACP0422_RS13810	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
LACP0422_RS13820	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
LACP0422_RS13825	COG4851	CamS sex pheromone cAM373 precursor
LACP0422_RS13830	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
LACP0422_RS13835	COG0154	amidase activity
LACP0422_RS13840	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
LACP0422_RS13845	COG1597	lipid kinase activity
LACP0422_RS13850	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
LACP0422_RS13865	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
LACP0422_RS13875	COG1737	Transcriptional regulator
LACP0422_RS13890	COG1278	Cold shock
LACP0422_RS13895	COG0673	inositol 2-dehydrogenase activity
LACP0422_RS13900	COG0513	Belongs to the DEAD box helicase family
LACP0422_RS13915	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
LACP0422_RS13940	COG2801	Transposase and inactivated derivatives
LACP0422_RS13950	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
LACP0422_RS13960	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
LACP0422_RS13970	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
LACP0422_RS13975	COG0562	UDP-galactopyranose mutase
LACP0422_RS14005	COG1216	Glycosyl transferase, family 2
LACP0422_RS14005	COG1442	glycosyl transferase family 8
LACP0422_RS14025	COG2244	polysaccharide biosynthetic process
LACP0422_RS14060	COG2207	Transcriptional regulator
LACP0422_RS14060	COG1609	Transcriptional regulator
LACP0422_RS14080	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
LACP0422_RS14115	COG2137	regulation of response to DNA damage stimulus
LACP0422_RS14120	COG3557	Belongs to the UPF0374 family
LACP0422_RS14140	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
LACP0422_RS14150	COG0628	permease
LACP0422_RS14155	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
LACP0422_RS14160	COG2610	gluconate transmembrane transporter activity
LACP0422_RS14165	COG1070	Carbohydrate kinase
LACP0422_RS14170	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
LACP0422_RS14175	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LACP0422_RS14180	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
LACP0422_RS14210	COG4166	transmembrane transport
LACP0422_RS14215	COG0601	transmembrane transport
LACP0422_RS14220	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LACP0422_RS14225	COG0444	Belongs to the ABC transporter superfamily
LACP0422_RS14230	COG4608	Belongs to the ABC transporter superfamily
LACP0422_RS14240	COG0582	viral genome integration into host DNA
LACP0422_RS14245	COG0542	response to heat
LACP0422_RS14265	COG0438	transferase activity, transferring glycosyl groups
LACP0422_RS14270	COG0438	transferase activity, transferring glycosyl groups
LACP0422_RS14280	COG1686	Belongs to the peptidase S11 family
LACP0422_RS14285	COG0436	Aminotransferase
LACP0422_RS14290	COG4703	Protein of unknown function (DUF1797)
LACP0422_RS14295	COG1368	sulfuric ester hydrolase activity
LACP0422_RS14380	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
LACP0422_RS14400	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
LACP0422_RS14410	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
LACP0422_RS14415	COG0833	amino acid
LACP0422_RS14420	COG2040	homocysteine
LACP0422_RS14425	COG0438	transferase activity, transferring glycosyl groups
LACP0422_RS14435	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
LACP0422_RS14440	COG0477	Major facilitator Superfamily
LACP0422_RS14455	COG0438	transferase activity, transferring glycosyl groups
LACP0422_RS14470	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
LACP0422_RS14480	COG0495	leucyl-tRNA aminoacylation
LACP0422_RS14485	COG2244	polysaccharide biosynthetic process
LACP0422_RS14490	COG1187	pseudouridine synthase activity
LACP0422_RS14495	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
LACP0422_RS14500	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
LACP0422_RS14510	COG3842	ATPase activity
LACP0422_RS14515	COG1175	transmembrane transport
LACP0422_RS14520	COG0395	ABC-type sugar transport system, permease component
LACP0422_RS14530	COG0584	glycerophosphoryl diester phosphodiesterase
LACP0422_RS14535	COG1428	Deoxynucleoside kinase
LACP0422_RS14540	COG1970	mechanosensitive ion channel activity
LACP0422_RS14545	COG1511	domain protein
LACP0422_RS14545	COG1511	domain protein
LACP0422_RS14575	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
LACP0422_RS14580	COG0789	Transcriptional regulator
LACP0422_RS14590	COG0697	spore germination
LACP0422_RS14595	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
LACP0422_RS14610	COG1902	pentaerythritol trinitrate reductase activity
LACP0422_RS14625	COG0561	phosphatase activity
LACP0422_RS14640	COG3279	Response regulator of the LytR AlgR family
LACP0422_RS14660	COG1846	Transcriptional regulator
LACP0422_RS14675	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
LACP0422_RS14710	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
LACP0422_RS14710	COG0646	methionine synthase
LACP0422_RS14715	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
LACP0422_RS14725	COG2046	Belongs to the sulfate adenylyltransferase family
LACP0422_RS14730	COG0529	Catalyzes the synthesis of activated sulfate
LACP0422_RS14735	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
LACP0422_RS14745	COG3273	potassium ion transport
LACP0422_RS14745	COG0471	metal ion transport
LACP0422_RS14750	COG0534	Mate efflux family protein
LACP0422_RS14770	COG2153	protein acetylation
LACP0422_RS14775	COG0018	arginyl-trna synthetase
LACP0422_RS14785	COG0577	efflux transmembrane transporter activity
LACP0422_RS14785	COG1136	(ABC) transporter
LACP0422_RS14805	COG1447	Phosphotransferase system cellobiose-specific component IIA
LACP0422_RS14810	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
LACP0422_RS14815	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
LACP0422_RS14820	COG2723	6-phospho-beta-galactosidase activity
LACP0422_RS14830	COG1376	ErfK ybiS ycfS ynhG family protein
LACP0422_RS14835	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LACP0422_RS14840	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LACP0422_RS14850	COG0436	Aminotransferase
LACP0422_RS14855	COG1438	arginine binding
LACP0422_RS14860	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
LACP0422_RS14865	COG3679	Belongs to the UPF0342 family
LACP0422_RS14870	COG0420	3'-5' exonuclease activity
LACP0422_RS14875	COG4717	serine-type aminopeptidase activity
LACP0422_RS14880	COG3481	metal-dependent phosphohydrolase, HD sub domain
LACP0422_RS14895	COG0583	DNA-binding transcription factor activity
LACP0422_RS14905	COG0431	NADPH-dependent FMN reductase
LACP0422_RS14905	COG1053	succinate dehydrogenase
LACP0422_RS14905	COG3976	FMN-binding domain protein
LACP0422_RS14920	COG3850	Histidine kinase
LACP0422_RS14920	COG5002	protein histidine kinase activity
LACP0422_RS14925	COG0745	RESPONSE REGULATOR receiver
LACP0422_RS14935	COG0463	Glycosyl transferase, family 2
LACP0422_RS14940	COG0586	Pfam SNARE associated Golgi protein
LACP0422_RS14945	COG0463	Glycosyl transferase, family 2
LACP0422_RS14965	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
LACP0422_RS14965	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
LACP0422_RS14970	COG0307	riboflavin synthase, alpha
LACP0422_RS14975	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
LACP0422_RS14975	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
LACP0422_RS14980	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
LACP0422_RS14995	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
LACP0422_RS15005	COG0446	pyridine nucleotide-disulphide oxidoreductase
LACP0422_RS15035	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
LACP0422_RS15045	COG0537	adenosine 5'-monophosphoramidase activity
LACP0422_RS15050	COG1131	(ABC) transporter
LACP0422_RS15055	COG4473	ABC transporter
LACP0422_RS15060	COG0510	thiamine kinase activity
LACP0422_RS15065	COG0220	tRNA (guanine-N7-)-methyltransferase activity
LACP0422_RS15075	COG0582	viral genome integration into host DNA
LACP0422_RS15320	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
LACP0422_RS15325	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LACP0422_RS15330	COG3715	PTS system
LACP0422_RS15335	COG3716	PTS system mannose fructose sorbose family IID component
LACP0422_RS15345	COG3414	Phosphotransferase system galactitol-specific IIB component
LACP0422_RS15350	COG2826	transposase and inactivated derivatives, IS30 family
LACP0422_RS15370	COG3158	transport of potassium into the cell
LACP0422_RS15395	COG1215	transferase activity, transferring glycosyl groups
LACP0422_RS15415	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
LACP0422_RS15430	COG0860	N-Acetylmuramoyl-L-alanine amidase
LACP0422_RS15440	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
LACP0422_RS15445	COG0267	Belongs to the bacterial ribosomal protein bL33 family
LACP0422_RS15455	COG0333	Belongs to the bacterial ribosomal protein bL32 family
LACP0422_RS15460	COG1113	amino acid transport
LACP0422_RS15480	COG1914	H( )-stimulated, divalent metal cation uptake system
LACP0422_RS15565	COG1418	mRNA catabolic process
LACP0422_RS15570	COG0477	Major facilitator Superfamily
LACP0422_RS15595	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
LACP0422_RS15625	COG3715	PTS system
LACP0422_RS15630	COG3716	PTS system mannose fructose sorbose family IID component
LACP0422_RS15640	COG3328	transposase activity
LACP0422_RS15655	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LACP0422_RS15670	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
LACP0422_RS15750	COG2826	transposase and inactivated derivatives, IS30 family
LACP0422_RS15770	COG2814	Major facilitator Superfamily
LACP0422_RS15795	COG1192	Involved in chromosome partitioning
LACP0422_RS15800	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
LACP0422_RS15905	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
LACP0422_RS15905	COG0551	DNA topoisomerase type I activity