locus-tag	class	description
AVR82_RS00010	COG0556	nucleotide-excision repair
AVR82_RS00020	COG2814	Major facilitator Superfamily
AVR82_RS00030	COG0446	pyridine nucleotide-disulphide oxidoreductase
AVR82_RS00040	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AVR82_RS00050	COG2323	membrane
AVR82_RS00055	COG0492	ferredoxin-NADP+ reductase activity
AVR82_RS00070	COG1215	transferase activity, transferring glycosyl groups
AVR82_RS00090	COG0446	pyridine nucleotide-disulphide oxidoreductase
AVR82_RS00100	COG1210	Utp--glucose-1-phosphate uridylyltransferase
AVR82_RS00105	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
AVR82_RS00110	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
AVR82_RS00115	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
AVR82_RS00120	COG1950	PFAM Membrane protein of
AVR82_RS00125	COG1983	PspC domain protein
AVR82_RS00130	COG0704	Plays a role in the regulation of phosphate uptake
AVR82_RS00135	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
AVR82_RS00140	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
AVR82_RS00145	COG0581	inorganic phosphate transmembrane transporter activity
AVR82_RS00150	COG0573	inorganic phosphate transmembrane transporter activity
AVR82_RS00155	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
AVR82_RS00160	COG5002	protein histidine kinase activity
AVR82_RS00165	COG0745	RESPONSE REGULATOR receiver
AVR82_RS00180	COG0653	protein targeting
AVR82_RS00195	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
AVR82_RS00200	COG1739	Uncharacterized protein family UPF0029
AVR82_RS00205	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
AVR82_RS00210	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AVR82_RS00215	COG0531	amino acid
AVR82_RS00220	COG0459	protein refolding
AVR82_RS00225	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
AVR82_RS00235	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
AVR82_RS00240	COG0488	(ABC) transporter
AVR82_RS00245	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
AVR82_RS00250	COG0456	acetyltransferase
AVR82_RS00255	COG0456	acetyltransferase
AVR82_RS00260	COG1214	PFAM Peptidase M22, glycoprotease
AVR82_RS00270	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
AVR82_RS00280	COG3639	organic phosphonate transmembrane transporter activity
AVR82_RS00285	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AVR82_RS00290	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
AVR82_RS00295	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AVR82_RS00310	COG4467	Involved in initiation control of chromosome replication
AVR82_RS00315	COG0470	DNA polymerase III
AVR82_RS00320	COG3870	Protein conserved in bacteria
AVR82_RS00325	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
AVR82_RS00345	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
AVR82_RS00360	COG2813	Specifically methylates the guanine in position
AVR82_RS00365	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
AVR82_RS00370	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AVR82_RS00380	COG1611	Belongs to the LOG family
AVR82_RS00655	COG1396	sequence-specific DNA binding
AVR82_RS00690	COG0222	ribosome binding
AVR82_RS00695	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
AVR82_RS00700	COG0081	regulation of translation
AVR82_RS00705	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
AVR82_RS00715	COG0250	Participates in transcription elongation, termination and antitermination
AVR82_RS00725	COG0267	Belongs to the bacterial ribosomal protein bL33 family
AVR82_RS00740	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AVR82_RS00745	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
AVR82_RS00750	COG0215	cysteine-tRNA ligase activity
AVR82_RS00755	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AVR82_RS00760	COG4956	integral membrane protein (PIN domain superfamily)
AVR82_RS00770	COG0756	dUTP diphosphatase activity
AVR82_RS00780	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
AVR82_RS00795	COG0588	phosphoglycerate mutase activity
AVR82_RS00800	COG0697	spore germination
AVR82_RS00810	COG1316	TRANSCRIPTIONal
AVR82_RS00815	COG0825	malonyl-CoA metabolic process
AVR82_RS00825	COG0439	Biotin carboxylase
AVR82_RS00835	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AVR82_RS00840	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
AVR82_RS00840	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AVR82_RS00845	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AVR82_RS00845	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
AVR82_RS00850	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
AVR82_RS00850	COG3933	PFAM sigma-54 factor interaction domain-containing protein
AVR82_RS00860	COG3716	PTS system mannose fructose sorbose family IID component
AVR82_RS00865	COG3715	PTS system
AVR82_RS00890	COG3409	Peptidoglycan-binding domain 1 protein
AVR82_RS00905	COG0083	homoserine kinase activity
AVR82_RS00910	COG0460	homoserine dehydrogenase
AVR82_RS00915	COG3091	SprT-like family
AVR82_RS00920	COG2183	response to ionizing radiation
AVR82_RS00935	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
AVR82_RS00940	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
AVR82_RS00950	COG2188	Transcriptional regulator
AVR82_RS00960	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
AVR82_RS01010	COG3104	oligopeptide transport
AVR82_RS01050	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
AVR82_RS01055	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AVR82_RS01060	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
AVR82_RS01075	COG0037	tRNA processing
AVR82_RS01080	COG1098	S1 RNA binding domain
AVR82_RS01090	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
AVR82_RS01095	COG2244	polysaccharide biosynthetic process
AVR82_RS01100	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
AVR82_RS01105	COG0193	aminoacyl-tRNA hydrolase activity
AVR82_RS01110	COG0039	L-malate dehydrogenase activity
AVR82_RS01125	COG2267	carboxylic ester hydrolase activity
AVR82_RS01140	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
AVR82_RS01145	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AVR82_RS01150	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
AVR82_RS01155	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
AVR82_RS01160	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
AVR82_RS01165	COG0505	Belongs to the CarA family
AVR82_RS01170	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
AVR82_RS01190	COG3158	transport of potassium into the cell
AVR82_RS01195	COG2337	Toxic component of a toxin-antitoxin (TA) module
AVR82_RS01200	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AVR82_RS01205	COG0736	holo-[acyl-carrier-protein] synthase activity
AVR82_RS01215	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
AVR82_RS01225	COG0501	Belongs to the peptidase M48B family
AVR82_RS01230	COG1704	LemA family
AVR82_RS01235	COG3764	Sortase (surface protein transpeptidase)
AVR82_RS01245	COG0254	rRNA binding
AVR82_RS01250	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
AVR82_RS01255	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
AVR82_RS01270	COG1760	l-serine dehydratase
AVR82_RS01275	COG1760	l-serine dehydratase
AVR82_RS01280	COG0814	amino acid
AVR82_RS01285	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
AVR82_RS01290	COG0504	CTP synthase activity
AVR82_RS01295	COG3343	RNA polymerase activity
AVR82_RS01305	COG0095	Lipoate-protein ligase
AVR82_RS01310	COG1078	dGTPase activity
AVR82_RS01335	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
AVR82_RS01345	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
AVR82_RS01350	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
AVR82_RS01370	COG1321	iron dependent repressor
AVR82_RS01370	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AVR82_RS01375	COG1121	(ABC) transporter
AVR82_RS01380	COG1073	alpha beta
AVR82_RS01385	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
AVR82_RS01390	COG4466	Protein conserved in bacteria
AVR82_RS01395	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
AVR82_RS01400	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
AVR82_RS01405	COG0084	hydrolase, TatD family'
AVR82_RS01410	COG2814	Major facilitator Superfamily
AVR82_RS01415	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AVR82_RS01415	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AVR82_RS01425	COG1801	Protein of unknown function DUF72
AVR82_RS01430	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
AVR82_RS01445	COG0248	Ppx GppA phosphatase
AVR82_RS01460	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AVR82_RS01470	COG1940	carbohydrate kinase activity
AVR82_RS01475	COG2723	6-phospho-beta-galactosidase activity
AVR82_RS01480	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AVR82_RS01495	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AVR82_RS01500	COG2188	Transcriptional regulator
AVR82_RS01505	COG0180	Tryptophanyl-tRNA synthetase
AVR82_RS01510	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AVR82_RS01515	COG3973	AAA domain
AVR82_RS01550	COG2274	protein secretion by the type I secretion system
AVR82_RS01575	COG3279	Response regulator of the LytR AlgR family
AVR82_RS01600	COG0463	Glycosyl transferase, family 2
AVR82_RS01640	COG1114	Component of the transport system for branched-chain amino acids
AVR82_RS01645	COG0561	phosphatase activity
AVR82_RS01655	COG0561	phosphatase activity
AVR82_RS01665	COG0110	maltose O-acetyltransferase activity
AVR82_RS01715	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
AVR82_RS01725	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
AVR82_RS01735	COG1125	glycine betaine transport
AVR82_RS01750	COG0300	oxidoreductase activity
AVR82_RS01780	COG1881	PFAM PEBP family protein
AVR82_RS01785	COG3759	membrane
AVR82_RS01795	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
AVR82_RS01815	COG0004	ammonium transporteR
AVR82_RS01820	COG2814	Major facilitator Superfamily
AVR82_RS01835	COG1134	teichoic acid transport
AVR82_RS01840	COG1682	transport, permease protein
AVR82_RS01850	COG0436	Aminotransferase
AVR82_RS01865	COG1268	BioY protein
AVR82_RS01905	COG1012	belongs to the aldehyde dehydrogenase family
AVR82_RS01905	COG1454	alcohol dehydrogenase
AVR82_RS01915	COG1131	(ABC) transporter
AVR82_RS01920	COG1725	Transcriptional regulator
AVR82_RS01950	COG3842	ATPase activity
AVR82_RS01990	COG1252	NADH dehydrogenase
AVR82_RS01995	COG1846	Transcriptional regulator
AVR82_RS02005	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
AVR82_RS02035	COG3942	CHAP domain
AVR82_RS02035	COG1388	LysM domain
AVR82_RS02040	COG0741	lytic transglycosylase activity
AVR82_RS02055	COG1136	(ABC) transporter
AVR82_RS02060	COG0577	efflux transmembrane transporter activity
AVR82_RS02070	COG2818	Glycosylase
AVR82_RS02075	COG2409	Drug exporters of the RND superfamily
AVR82_RS02075	COG1033	growth of symbiont in host cell
AVR82_RS02085	COG2357	RelA SpoT domain protein
AVR82_RS02095	COG0277	FAD linked oxidase domain protein
AVR82_RS02100	COG1316	TRANSCRIPTIONal
AVR82_RS02115	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AVR82_RS02120	COG1737	Transcriptional regulator
AVR82_RS02130	COG0745	RESPONSE REGULATOR receiver
AVR82_RS02135	COG5002	protein histidine kinase activity
AVR82_RS02145	COG2814	Major facilitator Superfamily
AVR82_RS02165	COG1914	H( )-stimulated, divalent metal cation uptake system
AVR82_RS02170	COG1309	transcriptional regulator
AVR82_RS02175	COG1959	2 iron, 2 sulfur cluster binding
AVR82_RS02185	COG0163	prenyltransferase activity
AVR82_RS02195	COG2190	(PTS) system
AVR82_RS02195	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AVR82_RS02195	COG1263	PTS System
AVR82_RS02200	COG1263	PTS System
AVR82_RS02200	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AVR82_RS02200	COG2190	(PTS) system
AVR82_RS02205	COG0366	Alpha amylase catalytic
AVR82_RS02210	COG2188	Transcriptional regulator
AVR82_RS02235	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AVR82_RS02240	COG0626	cystathionine gamma-synthase activity
AVR82_RS02245	COG1045	serine acetyltransferase
AVR82_RS02265	COG3964	amidohydrolase
AVR82_RS02280	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AVR82_RS02285	COG2188	Transcriptional regulator
AVR82_RS02290	COG0431	NADPH-dependent FMN reductase
AVR82_RS02325	COG3118	belongs to the thioredoxin family
AVR82_RS02335	COG0246	Mannitol dehydrogenase
AVR82_RS02340	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
AVR82_RS02350	COG2213	PTS system mannitol-specific
AVR82_RS02360	COG0363	glucosamine-6-phosphate deaminase activity
AVR82_RS02375	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AVR82_RS02385	COG0386	Belongs to the glutathione peroxidase family
AVR82_RS02395	COG4172	Belongs to the ABC transporter superfamily
AVR82_RS02405	COG0488	(ABC) transporter
AVR82_RS02410	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
AVR82_RS02415	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
AVR82_RS02445	COG0667	Aldo Keto reductase
AVR82_RS02450	COG0406	alpha-ribazole phosphatase activity
AVR82_RS02455	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
AVR82_RS02460	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AVR82_RS02470	COG4166	transmembrane transport
AVR82_RS02500	COG1757	Na H antiporter
AVR82_RS02550	COG3842	ATPase activity
AVR82_RS02555	COG0366	Alpha amylase catalytic
AVR82_RS02565	COG3833	ABC-type maltose transport systems, permease component
AVR82_RS02570	COG1175	transmembrane transport
AVR82_RS02575	COG2182	Extracellular solute-binding protein
AVR82_RS02580	COG0366	Alpha amylase catalytic
AVR82_RS02585	COG1609	Transcriptional regulator
AVR82_RS02590	COG1609	Transcriptional regulator
AVR82_RS02595	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
AVR82_RS02600	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
AVR82_RS02605	COG1461	Dihydroxyacetone kinase
AVR82_RS02610	COG2376	Dihydroxyacetone kinase
AVR82_RS02615	COG2376	Dihydroxyacetone kinase
AVR82_RS02620	COG1309	transcriptional regulator
AVR82_RS02625	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
AVR82_RS02630	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
AVR82_RS02645	COG1131	(ABC) transporter
AVR82_RS02650	COG1028	Short-chain dehydrogenase reductase Sdr
AVR82_RS02675	COG2188	Transcriptional regulator
AVR82_RS02680	COG4720	Psort location CytoplasmicMembrane, score
AVR82_RS02685	COG1122	ATPase activity
AVR82_RS02690	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
AVR82_RS02720	COG0667	Aldo Keto reductase
AVR82_RS02725	COG0656	L-ascorbic acid biosynthetic process
AVR82_RS02730	COG2807	transmembrane transport
AVR82_RS02770	COG1983	PspC domain protein
AVR82_RS02780	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
AVR82_RS02785	COG2267	carboxylic ester hydrolase activity
AVR82_RS02795	COG1113	amino acid transport
AVR82_RS02810	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
AVR82_RS02820	COG0352	thiamine-phosphate diphosphorylase activity
AVR82_RS02825	COG0351	phosphomethylpyrimidine kinase
AVR82_RS02830	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
AVR82_RS02840	COG1606	tRNA processing
AVR82_RS02845	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
AVR82_RS02850	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
AVR82_RS02855	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
AVR82_RS02860	COG1691	(AIR) carboxylase
AVR82_RS02865	COG3875	lactate racemase activity
AVR82_RS02870	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AVR82_RS02875	COG0310	cobalt ion transport
AVR82_RS02880	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
AVR82_RS02885	COG1122	ATPase activity
AVR82_RS02910	COG4166	transmembrane transport
AVR82_RS02920	COG3022	response to hydroperoxide
AVR82_RS02925	COG2267	carboxylic ester hydrolase activity
AVR82_RS02940	COG0604	alcohol dehydrogenase
AVR82_RS02975	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
AVR82_RS02995	COG2368	4-hydroxyphenylacetate
AVR82_RS03000	COG2365	Tyrosine phosphatase family
AVR82_RS03010	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
AVR82_RS03015	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AVR82_RS03020	COG2508	Transcriptional regulator
AVR82_RS03025	COG0778	Nitroreductase
AVR82_RS03035	COG1028	Short-chain dehydrogenase reductase Sdr
AVR82_RS03040	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AVR82_RS03055	COG0471	metal ion transport
AVR82_RS03060	COG0431	NADPH-dependent FMN reductase
AVR82_RS03060	COG3976	FMN-binding domain protein
AVR82_RS03060	COG1053	succinate dehydrogenase
AVR82_RS03080	COG1573	uracil-dna glycosylase
AVR82_RS03085	COG1012	belongs to the aldehyde dehydrogenase family
AVR82_RS03095	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
AVR82_RS03100	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AVR82_RS03105	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
AVR82_RS03110	COG4853	Protein conserved in bacteria
AVR82_RS03120	COG5002	protein histidine kinase activity
AVR82_RS03125	COG0745	RESPONSE REGULATOR receiver
AVR82_RS03135	COG2226	methyltransferase
AVR82_RS03160	COG4695	Portal protein
AVR82_RS03220	COG1396	sequence-specific DNA binding
AVR82_RS03235	COG1278	Cold shock
AVR82_RS03245	COG1554	hydrolase, family 65, central catalytic
AVR82_RS03250	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AVR82_RS03260	COG3103	Sh3 type 3 domain protein
AVR82_RS03260	COG0366	Alpha amylase catalytic
AVR82_RS03265	COG0058	SHG alpha-glucan phosphorylase activity
AVR82_RS03270	COG0297	glycogen (starch) synthase activity
AVR82_RS03275	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
AVR82_RS03280	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
AVR82_RS03285	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
AVR82_RS03295	COG4166	transmembrane transport
AVR82_RS03300	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
AVR82_RS03305	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
AVR82_RS03310	COG2814	Major facilitator Superfamily
AVR82_RS03315	COG0305	Participates in initiation and elongation during chromosome replication
AVR82_RS03320	COG0359	binds to the 23S rRNA
AVR82_RS03330	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
AVR82_RS03335	COG0629	single-stranded DNA binding
AVR82_RS03340	COG0360	Binds together with S18 to 16S ribosomal RNA
AVR82_RS03350	COG0187	DNA topoisomerase II activity
AVR82_RS03355	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
AVR82_RS03360	COG2501	S4 domain
AVR82_RS03365	COG0592	DNA-directed DNA polymerase activity
AVR82_RS03370	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
AVR82_RS03375	COG0594	ribonuclease P activity
AVR82_RS03380	COG0706	membrane insertase activity
AVR82_RS03385	COG4166	transmembrane transport
AVR82_RS03395	COG1847	R3H domain protein
AVR82_RS03400	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
AVR82_RS03405	COG0445	tRNA wobble uridine modification
AVR82_RS03445	COG1307	EDD domain protein, DegV family
AVR82_RS03460	COG3479	Phenolic acid decarboxylase
AVR82_RS03465	COG1695	Transcriptional regulator
AVR82_RS03475	COG1012	belongs to the aldehyde dehydrogenase family
AVR82_RS03475	COG1454	alcohol dehydrogenase
AVR82_RS03480	COG1609	Transcriptional regulator
AVR82_RS03490	COG1869	D-ribose catabolic process
AVR82_RS03495	COG4975	Glucose uptake
AVR82_RS03515	COG3730	PTS system glucitol sorbitol-specific
AVR82_RS03520	COG3732	PTS system glucitol sorbitol-specific
AVR82_RS03535	COG2188	Transcriptional regulator
AVR82_RS03540	COG1132	(ABC) transporter
AVR82_RS03545	COG1132	(ABC) transporter
AVR82_RS03550	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AVR82_RS03550	COG2207	Transcriptional regulator
AVR82_RS03565	COG0395	ABC-type sugar transport system, permease component
AVR82_RS03570	COG1653	transport
AVR82_RS03575	COG0366	Alpha amylase catalytic
AVR82_RS03585	COG2972	Histidine kinase
AVR82_RS03590	COG4753	response regulator
AVR82_RS03590	COG2207	Transcriptional regulator
AVR82_RS03600	COG3842	ATPase activity
AVR82_RS03610	COG2188	Transcriptional regulator
AVR82_RS03620	COG0383	alpha-mannosidase activity
AVR82_RS03625	COG1940	carbohydrate kinase activity
AVR82_RS03630	COG2723	6-phospho-beta-galactosidase activity
AVR82_RS03660	COG2207	Transcriptional regulator
AVR82_RS03660	COG1609	Transcriptional regulator
AVR82_RS03730	COG1349	DNA-binding transcription factor activity
AVR82_RS03735	COG2207	Transcriptional regulator
AVR82_RS03740	COG2814	Major facilitator Superfamily
AVR82_RS03745	COG1070	Carbohydrate kinase
AVR82_RS03750	COG3254	rhamnose metabolic process
AVR82_RS03755	COG4806	L-rhamnose isomerase
AVR82_RS03760	COG0235	Class ii aldolase
AVR82_RS03775	COG0028	Belongs to the TPP enzyme family
AVR82_RS03780	COG1959	2 iron, 2 sulfur cluster binding
AVR82_RS03785	COG0028	Belongs to the TPP enzyme family
AVR82_RS03790	COG1304	FMN binding
AVR82_RS03805	COG4512	PFAM Accessory gene regulator B
AVR82_RS03825	COG1393	Belongs to the ArsC family
AVR82_RS03835	COG2261	transglycosylase associated protein
AVR82_RS03855	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
AVR82_RS03860	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AVR82_RS03880	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AVR82_RS03900	COG1737	Transcriptional regulator
AVR82_RS03905	COG1609	Transcriptional regulator
AVR82_RS03925	COG2160	L-arabinose isomerase activity
AVR82_RS03930	COG0110	maltose O-acetyltransferase activity
AVR82_RS03940	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
AVR82_RS03945	COG1349	DNA-binding transcription factor activity
AVR82_RS03955	COG3414	Phosphotransferase system galactitol-specific IIB component
AVR82_RS03960	COG3775	system Galactitol-specific IIC component
AVR82_RS03975	COG3711	transcriptional antiterminator
AVR82_RS03995	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
AVR82_RS04010	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
AVR82_RS04025	COG2211	Major facilitator Superfamily
AVR82_RS04045	COG1263	PTS System
AVR82_RS04045	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AVR82_RS04045	COG2190	(PTS) system
AVR82_RS04050	COG2723	6-phospho-beta-galactosidase activity
AVR82_RS04055	COG2723	6-phospho-beta-galactosidase activity
AVR82_RS04060	COG3711	transcriptional antiterminator
AVR82_RS04070	COG2723	6-phospho-beta-galactosidase activity
AVR82_RS04080	COG2971	BadF BadG BcrA BcrD
AVR82_RS04085	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
AVR82_RS04090	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AVR82_RS04095	COG2188	Transcriptional regulator
AVR82_RS04100	COG2267	carboxylic ester hydrolase activity
AVR82_RS04110	COG2271	Major facilitator Superfamily
AVR82_RS04125	COG1028	Short-chain dehydrogenase reductase Sdr
AVR82_RS04140	COG2271	Major facilitator Superfamily
AVR82_RS04145	COG0583	DNA-binding transcription factor activity
AVR82_RS04150	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
AVR82_RS04155	COG0710	3-dehydroquinate dehydratase activity
AVR82_RS04175	COG0667	Aldo Keto reductase
AVR82_RS04180	COG1609	Transcriptional regulator
AVR82_RS04185	COG2017	converts alpha-aldose to the beta-anomer
AVR82_RS04190	COG2211	Major facilitator Superfamily
AVR82_RS04190	COG2190	(PTS) system
AVR82_RS04210	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
AVR82_RS04215	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AVR82_RS04220	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
AVR82_RS04225	COG1609	Transcriptional regulator
AVR82_RS04230	COG2944	sequence-specific DNA binding
AVR82_RS04235	COG2184	nucleotidyltransferase activity
AVR82_RS04255	COG0477	Major facilitator Superfamily
AVR82_RS04265	COG1609	Transcriptional regulator
AVR82_RS04270	COG1874	Beta-galactosidase
AVR82_RS04280	COG1114	Component of the transport system for branched-chain amino acids
AVR82_RS04290	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
AVR82_RS04340	COG0446	pyridine nucleotide-disulphide oxidoreductase
AVR82_RS04350	COG3590	peptidase
AVR82_RS04355	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AVR82_RS04375	COG1937	Protein conserved in bacteria
AVR82_RS04380	COG3118	belongs to the thioredoxin family
AVR82_RS04385	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
AVR82_RS04390	COG2217	Heavy metal translocating P-type atpase
AVR82_RS04405	COG2226	methyltransferase
AVR82_RS04455	COG0076	glutamate decarboxylase activity
AVR82_RS04480	COG2207	Transcriptional regulator
AVR82_RS04515	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
AVR82_RS04520	COG1968	undecaprenyl-diphosphatase activity
AVR82_RS04540	COG0656	L-ascorbic acid biosynthetic process
AVR82_RS04550	COG0737	Belongs to the 5'-nucleotidase family
AVR82_RS04600	COG0477	Major facilitator Superfamily
AVR82_RS04625	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
AVR82_RS04640	COG0697	spore germination
AVR82_RS04660	COG0071	Belongs to the small heat shock protein (HSP20) family
AVR82_RS04675	COG1194	a g-specific adenine glycosylase
AVR82_RS04685	COG3189	MarR family transcriptional regulator
AVR82_RS04690	COG1393	Belongs to the ArsC family
AVR82_RS04705	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
AVR82_RS04715	COG1113	amino acid transport
AVR82_RS04720	COG1757	Na H antiporter
AVR82_RS04735	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
AVR82_RS04740	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
AVR82_RS04750	COG2315	Protein conserved in bacteria
AVR82_RS04760	COG2217	Heavy metal translocating P-type atpase
AVR82_RS04790	COG4989	oxidoreductase activity
AVR82_RS04795	COG2151	metal-sulfur cluster biosynthetic enzyme
AVR82_RS04805	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
AVR82_RS04810	COG1882	Formate acetyltransferase
AVR82_RS04815	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
AVR82_RS04845	COG2814	Major facilitator Superfamily
AVR82_RS04850	COG0803	Belongs to the bacterial solute-binding protein 9 family
AVR82_RS04865	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
AVR82_RS04870	COG0302	gtp cyclohydrolase
AVR82_RS04880	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
AVR82_RS04910	COG0640	Transcriptional regulator
AVR82_RS04915	COG1272	protein, Hemolysin III
AVR82_RS04930	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
AVR82_RS04935	COG0628	permease
AVR82_RS04950	COG3158	transport of potassium into the cell
AVR82_RS04955	COG0531	amino acid
AVR82_RS04965	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AVR82_RS04970	COG2365	Tyrosine phosphatase family
AVR82_RS04975	COG0516	GMP reductase activity
AVR82_RS04980	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
AVR82_RS04985	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
AVR82_RS05000	COG1929	Belongs to the glycerate kinase type-1 family
AVR82_RS05010	COG1562	ergosterol biosynthetic process
AVR82_RS05015	COG1233	COG1233 Phytoene dehydrogenase and related
AVR82_RS05020	COG2738	Putative neutral zinc metallopeptidase
AVR82_RS05025	COG1307	EDD domain protein, DegV family
AVR82_RS05035	COG1380	Effector of murein hydrolase LrgA
AVR82_RS05060	COG0735	belongs to the Fur family
AVR82_RS05090	COG1263	PTS System
AVR82_RS05090	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AVR82_RS05090	COG2190	(PTS) system
AVR82_RS05105	COG3711	transcriptional antiterminator
AVR82_RS05105	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AVR82_RS05110	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AVR82_RS05110	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AVR82_RS05110	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AVR82_RS05115	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AVR82_RS05120	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AVR82_RS05120	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AVR82_RS05120	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AVR82_RS05125	COG0383	alpha-mannosidase activity
AVR82_RS05135	COG0561	phosphatase activity
AVR82_RS05150	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AVR82_RS05155	COG4619	ABC transporter
AVR82_RS05160	COG0390	transport system, permease component
AVR82_RS05175	COG1609	Transcriptional regulator
AVR82_RS05180	COG0366	Alpha amylase catalytic
AVR82_RS05185	COG1263	PTS System
AVR82_RS05185	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AVR82_RS05185	COG2190	(PTS) system
AVR82_RS05210	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AVR82_RS05215	COG1126	abc transporter atp-binding protein
AVR82_RS05220	COG0765	amino acid transport
AVR82_RS05225	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AVR82_RS05230	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AVR82_RS05235	COG0583	DNA-binding transcription factor activity
AVR82_RS05250	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AVR82_RS05255	COG0357	Ribosomal RNA small subunit methyltransferase G
AVR82_RS05265	COG1192	Involved in chromosome partitioning
AVR82_RS05270	COG1475	DNA binding
AVR82_RS05275	COG4481	Protein conserved in bacteria
AVR82_RS05280	COG0012	GTP binding
AVR82_RS05295	COG0517	IMP dehydrogenase activity
AVR82_RS05295	COG0516	GMP reductase activity
AVR82_RS05300	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AVR82_RS05320	COG1686	Belongs to the peptidase S11 family
AVR82_RS05325	COG1247	-acetyltransferase
AVR82_RS05365	COG0515	serine threonine protein kinase
AVR82_RS05365	COG2815	serine threonine protein kinase
AVR82_RS05375	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AVR82_RS05385	COG1940	carbohydrate kinase activity
AVR82_RS05385	COG1846	Transcriptional regulator
AVR82_RS05390	COG0628	permease
AVR82_RS05395	COG0588	phosphoglycerate mutase activity
AVR82_RS05425	COG0477	Major facilitator Superfamily
AVR82_RS05440	COG0656	L-ascorbic acid biosynthetic process
AVR82_RS05445	COG1376	ErfK ybiS ycfS ynhG family protein
AVR82_RS05455	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
AVR82_RS05465	COG0577	efflux transmembrane transporter activity
AVR82_RS05465	COG1136	(ABC) transporter
AVR82_RS05480	COG0693	protein deglycase activity
AVR82_RS05500	COG0789	Transcriptional regulator
AVR82_RS05520	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AVR82_RS05525	COG2723	6-phospho-beta-galactosidase activity
AVR82_RS05535	COG0783	Belongs to the Dps family
AVR82_RS05545	COG1053	succinate dehydrogenase
AVR82_RS05555	COG2816	NAD+ diphosphatase activity
AVR82_RS05565	COG0481	GTPase activity
AVR82_RS05600	COG1028	Short-chain dehydrogenase reductase Sdr
AVR82_RS05605	COG0110	maltose O-acetyltransferase activity
AVR82_RS05610	COG4221	oxidoreductase activity
AVR82_RS05620	COG1309	transcriptional regulator
AVR82_RS05625	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AVR82_RS05630	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AVR82_RS05635	COG1120	ATPase activity
AVR82_RS05640	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AVR82_RS05650	COG0477	Major facilitator Superfamily
AVR82_RS05655	COG4989	oxidoreductase activity
AVR82_RS05675	COG0300	oxidoreductase activity
AVR82_RS05680	COG1733	regulation of RNA biosynthetic process
AVR82_RS05695	COG1012	belongs to the aldehyde dehydrogenase family
AVR82_RS05705	COG1309	transcriptional regulator
AVR82_RS05720	COG3279	Response regulator of the LytR AlgR family
AVR82_RS05725	COG0367	asparagine synthase
AVR82_RS05735	COG2814	Major facilitator Superfamily
AVR82_RS05740	COG1733	regulation of RNA biosynthetic process
AVR82_RS05745	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AVR82_RS05785	COG1063	alcohol dehydrogenase
AVR82_RS05840	COG2217	Heavy metal translocating P-type atpase
AVR82_RS05860	COG0531	amino acid
AVR82_RS05875	COG1028	Short-chain dehydrogenase reductase Sdr
AVR82_RS05880	COG1473	amidohydrolase
AVR82_RS05890	COG1132	(ABC) transporter
AVR82_RS05895	COG1132	(ABC) transporter
AVR82_RS05940	COG4221	oxidoreductase activity
AVR82_RS05955	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AVR82_RS05980	COG0803	Belongs to the bacterial solute-binding protein 9 family
AVR82_RS06000	COG0741	lytic transglycosylase activity
AVR82_RS06005	COG0789	Transcriptional regulator
AVR82_RS06015	COG2723	6-phospho-beta-galactosidase activity
AVR82_RS06020	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AVR82_RS06025	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AVR82_RS06060	COG1136	(ABC) transporter
AVR82_RS06060	COG0577	efflux transmembrane transporter activity
AVR82_RS06070	COG0640	Transcriptional regulator
AVR82_RS06090	COG1914	H( )-stimulated, divalent metal cation uptake system
AVR82_RS06100	COG2246	polysaccharide biosynthetic process
AVR82_RS06105	COG5549	protein import
AVR82_RS06105	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AVR82_RS06120	COG0559	Belongs to the binding-protein-dependent transport system permease family
AVR82_RS06135	COG0410	ABC transporter
AVR82_RS06140	COG3620	sequence-specific DNA binding
AVR82_RS06140	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
AVR82_RS06140	COG0617	tRNA 3'-terminal CCA addition
AVR82_RS06170	COG4120	Belongs to the binding-protein-dependent transport system permease family
AVR82_RS06180	COG2190	(PTS) system
AVR82_RS06180	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AVR82_RS06180	COG1263	PTS System
AVR82_RS06185	COG0778	Nitroreductase
AVR82_RS06195	COG1132	(ABC) transporter
AVR82_RS06200	COG1940	carbohydrate kinase activity
AVR82_RS06225	COG0697	spore germination
AVR82_RS06270	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
AVR82_RS06280	COG0583	DNA-binding transcription factor activity
AVR82_RS06300	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AVR82_RS06310	COG0242	peptide deformylase activity
AVR82_RS06320	COG1328	CTP reductase activity
AVR82_RS06330	COG2200	EAL domain
AVR82_RS06370	COG2270	Major facilitator Superfamily
AVR82_RS06385	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
AVR82_RS06395	COG0561	phosphatase activity
AVR82_RS06400	COG0488	(ABC) transporter
AVR82_RS06425	COG0640	Transcriptional regulator
AVR82_RS06435	COG1511	domain protein
AVR82_RS06435	COG1511	domain protein
AVR82_RS06450	COG2814	Major facilitator Superfamily
AVR82_RS06455	COG1132	(ABC) transporter
AVR82_RS06460	COG1132	(ABC) transporter
AVR82_RS06465	COG0667	Aldo Keto reductase
AVR82_RS06475	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
AVR82_RS06490	COG1011	Hydrolase
AVR82_RS06495	COG0110	maltose O-acetyltransferase activity
AVR82_RS06500	COG0589	response to stress
AVR82_RS06520	COG0656	L-ascorbic acid biosynthetic process
AVR82_RS06525	COG4221	oxidoreductase activity
AVR82_RS06545	COG0583	DNA-binding transcription factor activity
AVR82_RS06550	COG0656	L-ascorbic acid biosynthetic process
AVR82_RS06580	COG0656	L-ascorbic acid biosynthetic process
AVR82_RS06585	COG1028	Short-chain dehydrogenase reductase Sdr
AVR82_RS06590	COG1063	alcohol dehydrogenase
AVR82_RS06600	COG0583	DNA-binding transcription factor activity
AVR82_RS06625	COG0456	acetyltransferase
AVR82_RS06645	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
AVR82_RS06665	COG0789	Transcriptional regulator
AVR82_RS06680	COG4221	oxidoreductase activity
AVR82_RS06690	COG4152	abc transporter atp-binding protein
AVR82_RS06695	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AVR82_RS06710	COG0438	transferase activity, transferring glycosyl groups
AVR82_RS06720	COG0583	DNA-binding transcription factor activity
AVR82_RS06725	COG2855	membrane
AVR82_RS06730	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AVR82_RS06740	COG2814	Major facilitator Superfamily
AVR82_RS06750	COG2814	Major facilitator Superfamily
AVR82_RS06790	COG1136	(ABC) transporter
AVR82_RS06795	COG0577	efflux transmembrane transporter activity
AVR82_RS06810	COG0789	Transcriptional regulator
AVR82_RS06810	COG4978	Transcriptional regulator
AVR82_RS06815	COG1811	Na channel or pump
AVR82_RS06825	COG4990	cell redox homeostasis
AVR82_RS06840	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
AVR82_RS06845	COG4720	Psort location CytoplasmicMembrane, score
AVR82_RS06890	COG0531	amino acid
AVR82_RS06895	COG0710	3-dehydroquinate dehydratase activity
AVR82_RS06915	COG0716	FMN binding
AVR82_RS06940	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
AVR82_RS06945	COG0561	phosphatase activity
AVR82_RS06960	COG1216	Glycosyl transferase, family 2
AVR82_RS06965	COG2188	Transcriptional regulator
AVR82_RS06970	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AVR82_RS06975	COG1447	Phosphotransferase system cellobiose-specific component IIA
AVR82_RS06980	COG2723	6-phospho-beta-galactosidase activity
AVR82_RS06985	COG2723	6-phospho-beta-galactosidase activity
AVR82_RS06990	COG3048	D-serine ammonia-lyase activity
AVR82_RS06995	COG1131	(ABC) transporter
AVR82_RS07005	COG1309	transcriptional regulator
AVR82_RS07010	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
AVR82_RS07015	COG1827	regulation of RNA biosynthetic process
AVR82_RS07050	COG0494	nUDIX hydrolase
AVR82_RS07055	COG0110	maltose O-acetyltransferase activity
AVR82_RS07065	COG0561	phosphatase activity
AVR82_RS07075	COG0366	Alpha amylase catalytic
AVR82_RS07095	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
AVR82_RS07115	COG2246	polysaccharide biosynthetic process
AVR82_RS07125	COG0589	response to stress
AVR82_RS07135	COG1131	(ABC) transporter
AVR82_RS07140	COG1725	Transcriptional regulator
AVR82_RS07155	COG1136	(ABC) transporter
AVR82_RS07175	COG2365	Tyrosine phosphatase family
AVR82_RS07180	COG0095	Lipoate-protein ligase
AVR82_RS07185	COG0431	NADPH-dependent FMN reductase
AVR82_RS07185	COG1053	succinate dehydrogenase
AVR82_RS07185	COG3976	FMN-binding domain protein
AVR82_RS07190	COG0431	NADPH-dependent FMN reductase
AVR82_RS07190	COG1053	succinate dehydrogenase
AVR82_RS07190	COG3976	FMN-binding domain protein
AVR82_RS07200	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
AVR82_RS07205	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
AVR82_RS07210	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AVR82_RS07215	COG0047	phosphoribosylformylglycinamidine synthase activity
AVR82_RS07220	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AVR82_RS07230	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
AVR82_RS07235	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
AVR82_RS07240	COG0138	bifunctional purine biosynthesis protein purh
AVR82_RS07245	COG0151	Belongs to the GarS family
AVR82_RS07255	COG1215	transferase activity, transferring glycosyl groups
AVR82_RS07275	COG2252	PERMEase
AVR82_RS07280	COG2233	PERMEase
AVR82_RS07285	COG2508	Transcriptional regulator
AVR82_RS07290	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
AVR82_RS07295	COG0540	Belongs to the ATCase OTCase family
AVR82_RS07300	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
AVR82_RS07305	COG0505	Belongs to the CarA family
AVR82_RS07310	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
AVR82_RS07315	COG0167	dihydroorotate dehydrogenase activity
AVR82_RS07320	COG0284	orotidine-5'-phosphate decarboxylase activity
AVR82_RS07325	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
AVR82_RS07335	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
AVR82_RS07340	COG1074	ATP-dependent DNA helicase activity
AVR82_RS07350	COG0702	epimerase
AVR82_RS07355	COG0583	DNA-binding transcription factor activity
AVR82_RS07370	COG0436	Aminotransferase
AVR82_RS07375	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AVR82_RS07380	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
AVR82_RS07390	COG0604	alcohol dehydrogenase
AVR82_RS07395	COG0789	Transcriptional regulator
AVR82_RS07400	COG2814	Major facilitator Superfamily
AVR82_RS07405	COG0025	NhaP-type Na H and K H
AVR82_RS07410	COG1780	Probably involved in ribonucleotide reductase function
AVR82_RS07415	COG1253	flavin adenine dinucleotide binding
AVR82_RS07445	COG1418	mRNA catabolic process
AVR82_RS07455	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
AVR82_RS07460	COG2188	Transcriptional regulator
AVR82_RS07470	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
AVR82_RS07485	COG1396	sequence-specific DNA binding
AVR82_RS07490	COG0564	pseudouridine synthase activity
AVR82_RS07495	COG0589	response to stress
AVR82_RS07500	COG2188	Transcriptional regulator
AVR82_RS07505	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AVR82_RS07510	COG3715	PTS system
AVR82_RS07515	COG3716	PTS system mannose fructose sorbose family IID component
AVR82_RS07525	COG1705	Flagellar rod assembly protein muramidase FlgJ
AVR82_RS07530	COG0095	Lipoate-protein ligase
AVR82_RS07560	COG0626	cystathionine gamma-synthase activity
AVR82_RS07565	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AVR82_RS07570	COG1073	alpha beta
AVR82_RS07580	COG0028	Belongs to the TPP enzyme family
AVR82_RS07620	COG1725	Transcriptional regulator
AVR82_RS07625	COG1131	(ABC) transporter
AVR82_RS07635	COG1335	isochorismatase
AVR82_RS07640	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
AVR82_RS07645	COG0025	NhaP-type Na H and K H
AVR82_RS07650	COG0673	inositol 2-dehydrogenase activity
AVR82_RS07655	COG0673	inositol 2-dehydrogenase activity
AVR82_RS07660	COG1737	Transcriptional regulator
AVR82_RS07665	COG1609	Transcriptional regulator
AVR82_RS07685	COG1882	Formate acetyltransferase
AVR82_RS07690	COG1349	DNA-binding transcription factor activity
AVR82_RS07705	COG4975	Glucose uptake
AVR82_RS07710	COG0328	RNA-DNA hybrid ribonuclease activity
AVR82_RS07720	COG0778	Nitroreductase
AVR82_RS07725	COG2326	polyphosphate kinase activity
AVR82_RS07730	COG4932	domain protein
AVR82_RS07740	COG0492	ferredoxin-NADP+ reductase activity
AVR82_RS07745	COG0584	glycerophosphoryl diester phosphodiesterase
AVR82_RS07750	COG1368	sulfuric ester hydrolase activity
AVR82_RS07770	COG3548	integral membrane protein
AVR82_RS07785	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
AVR82_RS07810	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
AVR82_RS07815	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
AVR82_RS07820	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
AVR82_RS07825	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
AVR82_RS07830	COG0131	Imidazoleglycerol-phosphate dehydratase
AVR82_RS07835	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
AVR82_RS07840	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
AVR82_RS07845	COG0107	imidazoleglycerol-phosphate synthase activity
AVR82_RS07850	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
AVR82_RS07855	COG0140	phosphoribosyl-ATP diphosphatase activity
AVR82_RS07860	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AVR82_RS07865	COG0110	maltose O-acetyltransferase activity
AVR82_RS07870	COG0861	Integral membrane protein TerC family
AVR82_RS07875	COG2084	Dehydrogenase
AVR82_RS07880	COG0446	pyridine nucleotide-disulphide oxidoreductase
AVR82_RS07890	COG4120	Belongs to the binding-protein-dependent transport system permease family
AVR82_RS07900	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
AVR82_RS07905	COG2873	o-acetylhomoserine
AVR82_RS07915	COG1307	EDD domain protein, DegV family
AVR82_RS07920	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
AVR82_RS07925	COG2190	(PTS) system
AVR82_RS07925	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AVR82_RS07925	COG1263	PTS System
AVR82_RS07950	COG0488	(ABC) transporter
AVR82_RS07970	COG1522	sequence-specific DNA binding
AVR82_RS07975	COG0791	NLP P60 protein
AVR82_RS07990	COG0477	Major facilitator Superfamily
AVR82_RS08015	COG3830	Belongs to the UPF0237 family
AVR82_RS08020	COG2848	UPF0210 protein
AVR82_RS08025	COG0745	RESPONSE REGULATOR receiver
AVR82_RS08030	COG3850	Histidine kinase
AVR82_RS08030	COG5002	protein histidine kinase activity
AVR82_RS08035	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
AVR82_RS08040	COG4975	Glucose uptake
AVR82_RS08045	COG0166	Belongs to the GPI family
AVR82_RS08080	COG1396	sequence-specific DNA binding
AVR82_RS08205	COG1783	phage Terminase large subunit
AVR82_RS08335	COG0577	efflux transmembrane transporter activity
AVR82_RS08335	COG1136	(ABC) transporter
AVR82_RS08345	COG1132	(ABC) transporter
AVR82_RS08350	COG4886	Leucine-rich repeat (LRR) protein
AVR82_RS08350	COG4932	domain protein
AVR82_RS08415	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
AVR82_RS08425	COG1970	mechanosensitive ion channel activity
AVR82_RS08845	COG3728	DNA packaging
AVR82_RS08845	COG5484	DNA packaging
AVR82_RS08860	COG2868	ribosomal protein
AVR82_RS08990	COG0726	polysaccharide deacetylase
AVR82_RS09005	COG1132	(ABC) transporter
AVR82_RS09025	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AVR82_RS09035	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
AVR82_RS09040	COG1482	cell wall glycoprotein biosynthetic process
AVR82_RS09045	COG3442	glutamine amidotransferase
AVR82_RS09050	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
AVR82_RS09055	COG1435	thymidine kinase activity
AVR82_RS09060	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
AVR82_RS09065	COG2890	protein-(glutamine-N5) methyltransferase activity
AVR82_RS09070	COG0009	L-threonylcarbamoyladenylate synthase
AVR82_RS09075	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
AVR82_RS09080	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
AVR82_RS09090	COG2233	PERMEase
AVR82_RS09095	COG0356	it plays a direct role in the translocation of protons across the membrane
AVR82_RS09100	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
AVR82_RS09105	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
AVR82_RS09110	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
AVR82_RS09115	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
AVR82_RS09120	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
AVR82_RS09125	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
AVR82_RS09130	COG0355	proton-transporting ATP synthase activity, rotational mechanism
AVR82_RS09135	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
AVR82_RS09145	COG1077	Cell shape determining protein MreB Mrl
AVR82_RS09150	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
AVR82_RS09160	COG0772	Belongs to the SEDS family
AVR82_RS09165	COG0509	glycine decarboxylation via glycine cleavage system
AVR82_RS09170	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AVR82_RS09175	COG2011	ABC-type metal ion transport system permease component
AVR82_RS09180	COG1464	Belongs to the NlpA lipoprotein family
AVR82_RS09200	COG1181	Belongs to the D-alanine--D-alanine ligase family
AVR82_RS09220	COG0589	response to stress
AVR82_RS09235	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
AVR82_RS09240	COG2918	glutathione biosynthetic process
AVR82_RS09240	COG0189	ligase activity
AVR82_RS09245	COG1609	Transcriptional regulator
AVR82_RS09250	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AVR82_RS09255	COG3715	PTS system
AVR82_RS09260	COG3716	PTS system mannose fructose sorbose family IID component
AVR82_RS09270	COG0366	Alpha amylase catalytic
AVR82_RS09275	COG0640	Transcriptional regulator
AVR82_RS09290	COG4493	Belongs to the UPF0637 family
AVR82_RS09295	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
AVR82_RS09300	COG1956	GAF domain-containing protein
AVR82_RS09305	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
AVR82_RS09315	COG1104	cysteine desulfurase activity
AVR82_RS09320	COG0301	tRNA thio-modification
AVR82_RS09330	COG1181	Belongs to the D-alanine--D-alanine ligase family
AVR82_RS09330	COG2918	glutathione biosynthetic process
AVR82_RS09340	COG0525	valine-tRNA ligase activity
AVR82_RS09345	COG0285	dihydrofolate synthase activity
AVR82_RS09350	COG2003	Belongs to the UPF0758 family
AVR82_RS09355	COG1077	Cell shape determining protein MreB Mrl
AVR82_RS09360	COG1792	Involved in formation and maintenance of cell shape
AVR82_RS09370	COG0850	regulation of cytokinetic process
AVR82_RS09375	COG2894	cell division
AVR82_RS09380	COG0765	amino acid transport
AVR82_RS09385	COG1126	abc transporter atp-binding protein
AVR82_RS09390	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AVR82_RS09395	COG0527	aspartate kinase activity
AVR82_RS09400	COG0612	Peptidase, M16
AVR82_RS09405	COG0612	Peptidase, M16
AVR82_RS09410	COG1426	Protein conserved in bacteria
AVR82_RS09415	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
AVR82_RS09420	COG1546	Belongs to the CinA family
AVR82_RS09420	COG1058	Belongs to the CinA family
AVR82_RS09425	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
AVR82_RS09430	COG1418	mRNA catabolic process
AVR82_RS09435	COG1692	metallophosphoesterase
AVR82_RS09440	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
AVR82_RS09445	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
AVR82_RS09470	COG0632	four-way junction helicase activity
AVR82_RS09475	COG2255	four-way junction helicase activity
AVR82_RS09480	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
AVR82_RS09485	COG0343	queuine tRNA-ribosyltransferase activity
AVR82_RS09490	COG1862	Preprotein translocase
AVR82_RS09495	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AVR82_RS09500	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
AVR82_RS09505	COG0513	Belongs to the DEAD box helicase family
AVR82_RS09510	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
AVR82_RS09515	COG4472	Bacterial protein of unknown function (DUF965)
AVR82_RS09520	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
AVR82_RS09525	COG3906	Belongs to the UPF0473 family
AVR82_RS09535	COG1193	negative regulation of DNA recombination
AVR82_RS09540	COG3118	belongs to the thioredoxin family
AVR82_RS09545	COG1719	4-vinyl reductase, 4VR
AVR82_RS09550	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
AVR82_RS09555	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
AVR82_RS09565	COG0517	IMP dehydrogenase activity
AVR82_RS09570	COG2171	N-acyltransferase activity
AVR82_RS09575	COG1473	amidohydrolase
AVR82_RS09580	COG0668	transmembrane transport
AVR82_RS09595	COG0789	Transcriptional regulator
AVR82_RS09600	COG0006	proline dipeptidase activity
AVR82_RS09605	COG1609	Transcriptional regulator
AVR82_RS09620	COG0217	transcriptional regulatory protein
AVR82_RS09630	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AVR82_RS09660	COG0827	DNA restriction-modification system
AVR82_RS09665	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
AVR82_RS09670	COG1113	amino acid transport
AVR82_RS09680	COG0737	Belongs to the 5'-nucleotidase family
AVR82_RS09685	COG4470	Protein conserved in bacteria
AVR82_RS09690	COG0647	UMP catabolic process
AVR82_RS09700	COG0586	Pfam SNARE associated Golgi protein
AVR82_RS09710	COG1098	S1 RNA binding domain
AVR82_RS09855	COG1234	tRNA 3'-trailer cleavage
AVR82_RS09860	COG1393	Belongs to the ArsC family
AVR82_RS09865	COG4862	establishment of competence for transformation
AVR82_RS09875	COG1164	Oligoendopeptidase f
AVR82_RS09885	COG2357	RelA SpoT domain protein
AVR82_RS09890	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
AVR82_RS09895	COG0564	pseudouridine synthase activity
AVR82_RS09900	COG3142	Participates in the control of copper homeostasis
AVR82_RS09905	COG2706	6-phosphogluconolactonase activity
AVR82_RS09915	COG0628	permease
AVR82_RS09920	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
AVR82_RS09930	COG1114	Component of the transport system for branched-chain amino acids
AVR82_RS09940	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
AVR82_RS09945	COG1674	ftsk spoiiie
AVR82_RS09960	COG2001	Belongs to the MraZ family
AVR82_RS09965	COG0275	rRNA processing
AVR82_RS09975	COG0768	penicillin binding
AVR82_RS09980	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AVR82_RS09985	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
AVR82_RS09990	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
AVR82_RS09995	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
AVR82_RS10010	COG1799	cell septum assembly
AVR82_RS10015	COG0762	integral membrane protein
AVR82_RS10025	COG3599	regulation of cell shape
AVR82_RS10030	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
AVR82_RS10045	COG3279	Response regulator of the LytR AlgR family
AVR82_RS10055	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
AVR82_RS10060	COG0494	nUDIX hydrolase
AVR82_RS10070	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
AVR82_RS10075	COG1104	cysteine desulfurase activity
AVR82_RS10085	COG0482	sulfurtransferase activity
AVR82_RS10090	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AVR82_RS10095	COG0569	domain protein
AVR82_RS10125	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
AVR82_RS10130	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
AVR82_RS10135	COG3584	3D domain protein
AVR82_RS10135	COG1388	LysM domain
AVR82_RS10145	COG1597	lipid kinase activity
AVR82_RS10150	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
AVR82_RS10155	COG5503	Protein of unknown function (DUF1447)
AVR82_RS10165	COG0242	peptide deformylase activity
AVR82_RS10190	COG0039	L-malate dehydrogenase activity
AVR82_RS10195	COG4476	Belongs to the UPF0223 family
AVR82_RS10200	COG0483	inositol monophosphate 1-phosphatase activity
AVR82_RS10205	COG1217	gtp-binding protein TYPA
AVR82_RS10230	COG0772	Belongs to the SEDS family
AVR82_RS10235	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
AVR82_RS10240	COG4471	UPF0298 protein
AVR82_RS10245	COG0742	ribosomal rna small subunit methyltransferase
AVR82_RS10250	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
AVR82_RS10255	COG3480	Lon protease (S16) C-terminal proteolytic domain
AVR82_RS10260	COG1555	photosystem II stabilization
AVR82_RS10260	COG1596	polysaccharide export
AVR82_RS10265	COG2131	deaminase
AVR82_RS10270	COG2333	competence protein COMEC
AVR82_RS10270	COG0658	competence protein
AVR82_RS10275	COG1466	dna polymerase III delta subunit
AVR82_RS10280	COG0268	Binds directly to 16S ribosomal RNA
AVR82_RS10285	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
AVR82_RS10310	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
AVR82_RS10315	COG0544	peptidyl-prolyl cis-trans isomerase activity
AVR82_RS10320	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
AVR82_RS10325	COG0218	Necessary for normal cell division and for the maintenance of normal septation
AVR82_RS10340	COG0765	amino acid transport
AVR82_RS10345	COG1126	abc transporter atp-binding protein
AVR82_RS10350	COG0322	excinuclease ABC activity
AVR82_RS10360	COG0489	protein tyrosine kinase activity
AVR82_RS10370	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AVR82_RS10375	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
AVR82_RS10380	COG0438	transferase activity, transferring glycosyl groups
AVR82_RS10410	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AVR82_RS10410	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AVR82_RS10410	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AVR82_RS10415	COG1105	Belongs to the carbohydrate kinase PfkB family
AVR82_RS10420	COG1349	DNA-binding transcription factor activity
AVR82_RS10425	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
AVR82_RS10435	COG1234	tRNA 3'-trailer cleavage
AVR82_RS10440	COG0300	oxidoreductase activity
AVR82_RS10445	COG5416	Lipopolysaccharide assembly protein A domain
AVR82_RS10450	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
AVR82_RS10450	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
AVR82_RS10455	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
AVR82_RS10470	COG0393	Putative heavy-metal-binding
AVR82_RS10500	COG0772	Belongs to the SEDS family
AVR82_RS10510	COG1116	anion transmembrane transporter activity
AVR82_RS10525	COG0463	Glycosyl transferase, family 2
AVR82_RS10540	COG3425	synthase
AVR82_RS10550	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
AVR82_RS10555	COG4224	UPF0291 protein
AVR82_RS10560	COG3763	UPF0154 protein
AVR82_RS10565	COG0204	Acyl-transferase
AVR82_RS10570	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
AVR82_RS10575	COG2827	Endonuclease containing a URI domain
AVR82_RS10580	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AVR82_RS10590	COG0052	Belongs to the universal ribosomal protein uS2 family
AVR82_RS10595	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
AVR82_RS10600	COG0528	UMP kinase activity
AVR82_RS10605	COG0233	cytoplasmic translational termination
AVR82_RS10610	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
AVR82_RS10615	COG4589	Belongs to the CDS family
AVR82_RS10620	COG0750	zinc metalloprotease
AVR82_RS10625	COG0442	prolyl-tRNA aminoacylation
AVR82_RS10630	COG2176	DNA-directed DNA polymerase activity
AVR82_RS10635	COG0779	Required for maturation of 30S ribosomal subunits
AVR82_RS10640	COG0195	Participates in both transcription termination and antitermination
AVR82_RS10645	COG2740	Nucleic-acid-binding protein implicated in transcription termination
AVR82_RS10655	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
AVR82_RS10660	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
AVR82_RS10665	COG0738	Major facilitator superfamily
AVR82_RS10670	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
AVR82_RS10680	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
AVR82_RS10685	COG0287	Prephenate dehydrogenase
AVR82_RS10690	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
AVR82_RS10695	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
AVR82_RS10700	COG0196	riboflavin kinase activity
AVR82_RS10705	COG3527	Alpha-acetolactate decarboxylase
AVR82_RS10710	COG1420	regulation of RNA biosynthetic process
AVR82_RS10715	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
AVR82_RS10720	COG0443	Heat shock 70 kDa protein
AVR82_RS10725	COG0484	heat shock protein binding
AVR82_RS10730	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
AVR82_RS10740	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AVR82_RS10745	COG1696	Membrane protein involved in D-alanine export
AVR82_RS10750	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AVR82_RS10755	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
AVR82_RS10760	COG0481	GTPase activity
AVR82_RS10775	COG2094	Belongs to the DNA glycosylase MPG family
AVR82_RS10780	COG2264	protein methyltransferase activity
AVR82_RS10785	COG1385	rRNA (uridine-N3-)-methyltransferase activity
AVR82_RS10795	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AVR82_RS10800	COG1490	D-aminoacyl-tRNA deacylase activity
AVR82_RS10805	COG0546	phosphoglycolate phosphatase activity
AVR82_RS10810	COG3001	Fructosamine kinase
AVR82_RS10815	COG0860	N-Acetylmuramoyl-L-alanine amidase
AVR82_RS10815	COG3103	Sh3 type 3 domain protein
AVR82_RS10815	COG4991	sh3 domain protein
AVR82_RS10820	COG0124	histidyl-tRNA synthetase
AVR82_RS10825	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
AVR82_RS10835	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AVR82_RS10845	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
AVR82_RS10855	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
AVR82_RS10860	COG0828	Belongs to the bacterial ribosomal protein bS21 family
AVR82_RS10865	COG1610	YqeY-like protein
AVR82_RS10870	COG1702	phosphate starvation-inducible protein PhoH
AVR82_RS10875	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
AVR82_RS10880	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
AVR82_RS10885	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
AVR82_RS10890	COG1381	Involved in DNA repair and RecF pathway recombination
AVR82_RS10895	COG0752	glycyl-tRNA synthetase alpha subunit
AVR82_RS10900	COG0751	glycine-tRNA ligase activity
AVR82_RS10905	COG0358	DNA primase activity
AVR82_RS10910	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AVR82_RS10915	COG1725	Transcriptional regulator
AVR82_RS10920	COG1131	(ABC) transporter
AVR82_RS10940	COG1131	(ABC) transporter
AVR82_RS10955	COG0519	Catalyzes the synthesis of GMP from XMP
AVR82_RS10960	COG1131	(ABC) transporter
AVR82_RS10970	COG4585	Histidine kinase
AVR82_RS10975	COG2197	response regulator
AVR82_RS10980	COG0446	pyridine nucleotide-disulphide oxidoreductase
AVR82_RS10990	COG0604	alcohol dehydrogenase
AVR82_RS10995	COG0583	DNA-binding transcription factor activity
AVR82_RS11025	COG0546	phosphoglycolate phosphatase activity
AVR82_RS11045	COG1393	Belongs to the ArsC family
AVR82_RS11055	COG1349	DNA-binding transcription factor activity
AVR82_RS11060	COG0446	pyridine nucleotide-disulphide oxidoreductase
AVR82_RS11065	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AVR82_RS11075	COG0477	Major facilitator Superfamily
AVR82_RS11080	COG0148	phosphopyruvate hydratase activity
AVR82_RS11085	COG2217	Heavy metal translocating P-type atpase
AVR82_RS11105	COG1846	Transcriptional regulator
AVR82_RS11115	COG0574	Belongs to the PEP-utilizing enzyme family
AVR82_RS11115	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AVR82_RS11140	COG2384	SAM-dependent methyltransferase
AVR82_RS11145	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
AVR82_RS11155	COG0542	response to heat
AVR82_RS11165	COG0587	DNA-directed DNA polymerase activity
AVR82_RS11170	COG0205	6-phosphofructokinase activity
AVR82_RS11185	COG2996	Protein conserved in bacteria
AVR82_RS11190	COG4974	Belongs to the 'phage' integrase family
AVR82_RS11200	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
AVR82_RS11205	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
AVR82_RS11210	COG1187	pseudouridine synthase activity
AVR82_RS11215	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
AVR82_RS11225	COG0514	ATP-dependent DNA helicase (RecQ)
AVR82_RS11235	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
AVR82_RS11240	COG0539	negative regulation of cytoplasmic translation
AVR82_RS11245	COG1160	GTP binding
AVR82_RS11255	COG0457	Tetratricopeptide repeat
AVR82_RS11260	COG0561	phosphatase activity
AVR82_RS11265	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
AVR82_RS11270	COG0617	tRNA 3'-terminal CCA addition
AVR82_RS11280	COG0488	(ABC) transporter
AVR82_RS11285	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
AVR82_RS11290	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
AVR82_RS11295	COG1307	EDD domain protein, DegV family
AVR82_RS11300	COG2755	lipolytic protein G-D-S-L family
AVR82_RS11305	COG4698	Protein conserved in bacteria
AVR82_RS11310	COG4479	Belongs to the UPF0346 family
AVR82_RS11315	COG0793	Belongs to the peptidase S41A family
AVR82_RS11315	COG3409	Peptidoglycan-binding domain 1 protein
AVR82_RS11330	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
AVR82_RS11335	COG0604	alcohol dehydrogenase
AVR82_RS11340	COG1733	regulation of RNA biosynthetic process
AVR82_RS11350	COG1215	transferase activity, transferring glycosyl groups
AVR82_RS11365	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
AVR82_RS11370	COG1534	Rna-binding protein
AVR82_RS11375	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
AVR82_RS11380	COG1713	HD superfamily hydrolase involved in NAD metabolism
AVR82_RS11385	COG0799	negative regulation of ribosome biogenesis
AVR82_RS11390	COG2226	methyltransferase
AVR82_RS11395	COG1323	Belongs to the UPF0348 family
AVR82_RS11415	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
AVR82_RS11420	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
AVR82_RS11425	COG0745	RESPONSE REGULATOR receiver
AVR82_RS11430	COG5002	protein histidine kinase activity
AVR82_RS11440	COG0419	ATPase involved in DNA repair
AVR82_RS11455	COG0706	membrane insertase activity
AVR82_RS11460	COG1254	Belongs to the acylphosphatase family
AVR82_RS11465	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AVR82_RS11475	COG1733	regulation of RNA biosynthetic process
AVR82_RS11480	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
AVR82_RS11485	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AVR82_RS11485	COG0072	phenylalanine-tRNA ligase activity
AVR82_RS11490	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
AVR82_RS11495	COG0572	uridine kinase
AVR82_RS11500	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AVR82_RS11515	COG4841	protein insertion into membrane
AVR82_RS11525	COG0768	penicillin binding
AVR82_RS11530	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
AVR82_RS11535	COG0457	Tetratricopeptide repeat
AVR82_RS11535	COG0705	Rhomboid family
AVR82_RS11545	COG1940	carbohydrate kinase activity
AVR82_RS11565	COG0584	glycerophosphoryl diester phosphodiesterase
AVR82_RS11570	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
AVR82_RS11575	COG0789	Transcriptional regulator
AVR82_RS11620	COG0261	This protein binds to 23S rRNA in the presence of protein L20
AVR82_RS11630	COG0211	Belongs to the bacterial ribosomal protein bL27 family
AVR82_RS11635	COG0006	proline dipeptidase activity
AVR82_RS11640	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
AVR82_RS11645	COG1302	Protein conserved in bacteria
AVR82_RS11650	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AVR82_RS11655	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
AVR82_RS11660	COG1570	exodeoxyribonuclease VII activity
AVR82_RS11665	COG1722	exodeoxyribonuclease VII activity
AVR82_RS11670	COG0142	geranyltranstransferase activity
AVR82_RS11675	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
AVR82_RS11680	COG1438	arginine binding
AVR82_RS11685	COG0497	DNA recombination
AVR82_RS11700	COG1732	Glycine betaine
AVR82_RS11715	COG0194	GDP metabolic process
AVR82_RS11720	COG1758	RNA polymerase activity
AVR82_RS11725	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
AVR82_RS11730	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
AVR82_RS11735	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
AVR82_RS11740	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AVR82_RS11740	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
AVR82_RS11745	COG0631	protein serine/threonine phosphatase activity
AVR82_RS11750	COG0515	serine threonine protein kinase
AVR82_RS11750	COG2815	serine threonine protein kinase
AVR82_RS11755	COG1162	GTPase activity
AVR82_RS11760	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
AVR82_RS11765	COG1564	THIamine pyrophosphokinase
AVR82_RS11770	COG0227	Belongs to the bacterial ribosomal protein bL28 family
AVR82_RS11775	COG1302	Protein conserved in bacteria
AVR82_RS11780	COG1461	Dihydroxyacetone kinase
AVR82_RS11785	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
AVR82_RS11790	COG0416	fatty acid biosynthetic process
AVR82_RS11795	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AVR82_RS11800	COG0571	ribonuclease III activity
AVR82_RS11805	COG1196	nuclear chromosome segregation
AVR82_RS11810	COG0552	protein localization to endoplasmic reticulum
AVR82_RS11815	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
AVR82_RS11820	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
AVR82_RS11825	COG0228	four-way junction DNA binding
AVR82_RS11830	COG1837	Belongs to the UPF0109 family
AVR82_RS11835	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
AVR82_RS11840	COG0336	Belongs to the RNA methyltransferase TrmD family
AVR82_RS11845	COG0335	large ribosomal subunit rRNA binding
AVR82_RS11865	COG1131	(ABC) transporter
AVR82_RS11880	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AVR82_RS11880	COG0512	Glutamine amidotransferase of anthranilate synthase
AVR82_RS11885	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AVR82_RS11890	COG0134	indole-3-glycerol-phosphate synthase activity
AVR82_RS11895	COG0135	phosphoribosylanthranilate isomerase activity
AVR82_RS11900	COG0133	tryptophan synthase activity
AVR82_RS11905	COG0159	tryptophan synthase activity
AVR82_RS11920	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AVR82_RS11930	COG1473	amidohydrolase
AVR82_RS11935	COG1063	alcohol dehydrogenase
AVR82_RS11945	COG0300	oxidoreductase activity
AVR82_RS11955	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AVR82_RS11960	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AVR82_RS11965	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AVR82_RS11970	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
AVR82_RS11975	COG1028	Short-chain dehydrogenase reductase Sdr
AVR82_RS11980	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AVR82_RS11995	COG0439	Biotin carboxylase
AVR82_RS12010	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
AVR82_RS12020	COG1811	Na channel or pump
AVR82_RS12025	COG0583	DNA-binding transcription factor activity
AVR82_RS12030	COG1607	acyl-coa hydrolase
AVR82_RS12035	COG1162	GTPase activity
AVR82_RS12045	COG0477	Major facilitator Superfamily
AVR82_RS12090	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AVR82_RS12095	COG3397	chitin binding
AVR82_RS12110	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
AVR82_RS12120	COG3152	Membrane
AVR82_RS12125	COG1597	lipid kinase activity
AVR82_RS12135	COG2261	transglycosylase associated protein
AVR82_RS12140	COG3237	CsbD-like
AVR82_RS12155	COG1942	4-Oxalocrotonate Tautomerase
AVR82_RS12190	COG0531	amino acid
AVR82_RS12195	COG0561	phosphatase activity
AVR82_RS12200	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
AVR82_RS12200	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
AVR82_RS12220	COG2017	converts alpha-aldose to the beta-anomer
AVR82_RS12225	COG1304	FMN binding
AVR82_RS12245	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AVR82_RS12245	COG1199	ATP-dependent helicase activity
AVR82_RS12260	COG0017	Asparaginyl-tRNA synthetase
AVR82_RS12275	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AVR82_RS12280	COG2011	ABC-type metal ion transport system permease component
AVR82_RS12285	COG1464	Belongs to the NlpA lipoprotein family
AVR82_RS12295	COG1177	transmembrane transport
AVR82_RS12300	COG1840	ABC-type Fe3 transport system, periplasmic component
AVR82_RS12315	COG3331	DNA recombination
AVR82_RS12320	COG4474	Belongs to the UPF0398 family
AVR82_RS12325	COG3599	regulation of cell shape
AVR82_RS12335	COG0116	Belongs to the methyltransferase superfamily
AVR82_RS12340	COG1073	alpha beta
AVR82_RS12350	COG1216	Glycosyl transferase, family 2
AVR82_RS12370	COG1619	proteins homologs of microcin C7 resistance protein MccF
AVR82_RS12395	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AVR82_RS12410	COG2759	Belongs to the formate--tetrahydrofolate ligase family
AVR82_RS12415	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
AVR82_RS12420	COG0564	pseudouridine synthase activity
AVR82_RS12425	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
AVR82_RS12430	COG0505	Belongs to the CarA family
AVR82_RS12435	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
AVR82_RS12450	COG5646	InterPro IPR014922
AVR82_RS12475	COG1131	(ABC) transporter
AVR82_RS12485	COG1293	RNA-binding protein homologous to eukaryotic snRNP
AVR82_RS12495	COG1307	EDD domain protein, DegV family
AVR82_RS12550	COG1113	amino acid transport
AVR82_RS12570	COG1620	l-lactate permease
AVR82_RS12580	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
AVR82_RS12605	COG1846	Transcriptional regulator
AVR82_RS12610	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AVR82_RS12645	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AVR82_RS12650	COG1227	inorganic diphosphatase activity
AVR82_RS12655	COG0583	DNA-binding transcription factor activity
AVR82_RS12665	COG0187	DNA topoisomerase II activity
AVR82_RS12670	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
AVR82_RS12680	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
AVR82_RS12685	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
AVR82_RS12690	COG4974	Belongs to the 'phage' integrase family
AVR82_RS12695	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
AVR82_RS12700	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AVR82_RS12705	COG0758	DNA mediated transformation
AVR82_RS12710	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
AVR82_RS12715	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
AVR82_RS12720	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
AVR82_RS12725	COG0583	DNA-binding transcription factor activity
AVR82_RS12740	COG2814	Major facilitator Superfamily
AVR82_RS12750	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
AVR82_RS12755	COG0291	Belongs to the bacterial ribosomal protein bL35 family
AVR82_RS12760	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
AVR82_RS12765	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
AVR82_RS12770	COG1484	DNA-dependent DNA replication
AVR82_RS12775	COG3611	Membrane attachment protein
AVR82_RS12780	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
AVR82_RS12785	COG0237	dephospho-CoA kinase activity
AVR82_RS12790	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
AVR82_RS12795	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AVR82_RS12795	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AVR82_RS12810	COG2151	metal-sulfur cluster biosynthetic enzyme
AVR82_RS12815	COG0719	Fe-S assembly protein
AVR82_RS12825	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AVR82_RS12830	COG0719	Fe-S assembly protein
AVR82_RS12850	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AVR82_RS12855	COG1674	ftsk spoiiie
AVR82_RS12860	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AVR82_RS12870	COG0220	tRNA (guanine-N7-)-methyltransferase activity
AVR82_RS12875	COG0510	thiamine kinase activity
AVR82_RS12880	COG4473	ABC transporter
AVR82_RS12885	COG1131	(ABC) transporter
AVR82_RS12890	COG0537	adenosine 5'-monophosphoramidase activity
AVR82_RS12900	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AVR82_RS12930	COG0446	pyridine nucleotide-disulphide oxidoreductase
AVR82_RS12940	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AVR82_RS12955	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
AVR82_RS12960	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AVR82_RS12960	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AVR82_RS12965	COG0307	riboflavin synthase, alpha
AVR82_RS12970	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AVR82_RS12970	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AVR82_RS12990	COG0463	Glycosyl transferase, family 2
AVR82_RS12995	COG0586	Pfam SNARE associated Golgi protein
AVR82_RS13000	COG0463	Glycosyl transferase, family 2
AVR82_RS13010	COG0745	RESPONSE REGULATOR receiver
AVR82_RS13015	COG5002	protein histidine kinase activity
AVR82_RS13015	COG3850	Histidine kinase
AVR82_RS13030	COG3976	FMN-binding domain protein
AVR82_RS13030	COG1053	succinate dehydrogenase
AVR82_RS13030	COG0431	NADPH-dependent FMN reductase
AVR82_RS13040	COG0583	DNA-binding transcription factor activity
AVR82_RS13055	COG3481	metal-dependent phosphohydrolase, HD sub domain
AVR82_RS13060	COG4717	serine-type aminopeptidase activity
AVR82_RS13065	COG0420	3'-5' exonuclease activity
AVR82_RS13070	COG3679	Belongs to the UPF0342 family
AVR82_RS13075	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AVR82_RS13080	COG1438	arginine binding
AVR82_RS13085	COG0436	Aminotransferase
AVR82_RS13095	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AVR82_RS13100	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AVR82_RS13105	COG1376	ErfK ybiS ycfS ynhG family protein
AVR82_RS13115	COG2723	6-phospho-beta-galactosidase activity
AVR82_RS13120	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AVR82_RS13125	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AVR82_RS13130	COG1447	Phosphotransferase system cellobiose-specific component IIA
AVR82_RS13150	COG0577	efflux transmembrane transporter activity
AVR82_RS13150	COG1136	(ABC) transporter
AVR82_RS13160	COG0018	arginyl-trna synthetase
AVR82_RS13165	COG2153	protein acetylation
AVR82_RS13185	COG0534	Mate efflux family protein
AVR82_RS13190	COG3273	potassium ion transport
AVR82_RS13190	COG0471	metal ion transport
AVR82_RS13200	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
AVR82_RS13205	COG0529	Catalyzes the synthesis of activated sulfate
AVR82_RS13210	COG2046	Belongs to the sulfate adenylyltransferase family
AVR82_RS13220	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
AVR82_RS13225	COG0646	methionine synthase
AVR82_RS13225	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
AVR82_RS13465	COG1396	sequence-specific DNA binding
AVR82_RS13475	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AVR82_RS13500	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
AVR82_RS13515	COG1846	Transcriptional regulator
AVR82_RS13535	COG3279	Response regulator of the LytR AlgR family
AVR82_RS13550	COG0561	phosphatase activity
AVR82_RS13565	COG0789	Transcriptional regulator
AVR82_RS13570	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AVR82_RS13595	COG1511	domain protein
AVR82_RS13595	COG1511	domain protein
AVR82_RS13600	COG1970	mechanosensitive ion channel activity
AVR82_RS13605	COG1428	Deoxynucleoside kinase
AVR82_RS13610	COG0584	glycerophosphoryl diester phosphodiesterase
AVR82_RS13620	COG0395	ABC-type sugar transport system, permease component
AVR82_RS13625	COG1175	transmembrane transport
AVR82_RS13640	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AVR82_RS13645	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
AVR82_RS13650	COG1187	pseudouridine synthase activity
AVR82_RS13655	COG2244	polysaccharide biosynthetic process
AVR82_RS13660	COG0495	leucyl-tRNA aminoacylation
AVR82_RS13670	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
AVR82_RS13685	COG0438	transferase activity, transferring glycosyl groups
AVR82_RS13705	COG0477	Major facilitator Superfamily
AVR82_RS13710	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
AVR82_RS13720	COG0438	transferase activity, transferring glycosyl groups
AVR82_RS13725	COG2040	homocysteine
AVR82_RS13730	COG0833	amino acid
AVR82_RS13735	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
AVR82_RS13745	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
AVR82_RS13765	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
AVR82_RS13855	COG1368	sulfuric ester hydrolase activity
AVR82_RS13860	COG4703	Protein of unknown function (DUF1797)
AVR82_RS13865	COG0436	Aminotransferase
AVR82_RS13870	COG1686	Belongs to the peptidase S11 family
AVR82_RS13880	COG0438	transferase activity, transferring glycosyl groups
AVR82_RS13885	COG0438	transferase activity, transferring glycosyl groups
AVR82_RS13905	COG0542	response to heat
AVR82_RS13910	COG0582	viral genome integration into host DNA
AVR82_RS13920	COG4608	Belongs to the ABC transporter superfamily
AVR82_RS13925	COG0444	Belongs to the ABC transporter superfamily
AVR82_RS13930	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AVR82_RS13935	COG0601	transmembrane transport
AVR82_RS13940	COG4166	transmembrane transport
AVR82_RS13970	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
AVR82_RS13975	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AVR82_RS13980	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
AVR82_RS13985	COG1070	Carbohydrate kinase
AVR82_RS13990	COG2610	gluconate transmembrane transporter activity
AVR82_RS13995	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
AVR82_RS14000	COG0628	permease
AVR82_RS14010	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
AVR82_RS14030	COG3557	Belongs to the UPF0374 family
AVR82_RS14035	COG2137	regulation of response to DNA damage stimulus
AVR82_RS14070	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
AVR82_RS14090	COG1609	Transcriptional regulator
AVR82_RS14090	COG2207	Transcriptional regulator
AVR82_RS14125	COG0562	UDP-galactopyranose mutase
AVR82_RS14225	COG5039	Polysaccharide pyruvyl transferase
AVR82_RS14240	COG0438	transferase activity, transferring glycosyl groups
AVR82_RS14250	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
AVR82_RS14260	COG4464	protein tyrosine phosphatase activity
AVR82_RS14265	COG0489	protein tyrosine kinase activity
AVR82_RS14275	COG0582	viral genome integration into host DNA
AVR82_RS14280	COG1088	dTDP-glucose 4,6-dehydratase activity
AVR82_RS14290	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
AVR82_RS14295	COG2244	polysaccharide biosynthetic process
AVR82_RS14340	COG0562	UDP-galactopyranose mutase
AVR82_RS14345	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
AVR82_RS14355	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
AVR82_RS14365	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
AVR82_RS14390	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AVR82_RS14655	COG0513	Belongs to the DEAD box helicase family
AVR82_RS14660	COG0673	inositol 2-dehydrogenase activity
AVR82_RS14665	COG1278	Cold shock
AVR82_RS14680	COG1737	Transcriptional regulator
AVR82_RS14690	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AVR82_RS14705	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AVR82_RS14710	COG1597	lipid kinase activity
AVR82_RS14715	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AVR82_RS14720	COG0154	amidase activity
AVR82_RS14725	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AVR82_RS14730	COG4851	CamS sex pheromone cAM373 precursor
AVR82_RS14735	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
AVR82_RS14745	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
AVR82_RS14750	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
AVR82_RS14755	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
AVR82_RS14760	COG1705	Flagellar rod assembly protein muramidase FlgJ
AVR82_RS14775	COG0142	geranyltranstransferase activity
AVR82_RS14790	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
AVR82_RS14795	COG4988	ABC transporter
AVR82_RS14800	COG1294	oxidase, subunit
AVR82_RS14805	COG1271	oxidase subunit
AVR82_RS14815	COG4684	Psort location CytoplasmicMembrane, score
AVR82_RS14820	COG0531	amino acid
AVR82_RS14830	COG0281	malic enzyme
AVR82_RS14835	COG0583	DNA-binding transcription factor activity
AVR82_RS14845	COG0583	DNA-binding transcription factor activity
AVR82_RS14855	COG1053	succinate dehydrogenase
AVR82_RS14860	COG0114	fumarate hydratase activity
AVR82_RS14880	COG3052	prosthetic group binding
AVR82_RS14900	COG0471	metal ion transport
AVR82_RS14905	COG0039	L-malate dehydrogenase activity
AVR82_RS14915	COG0803	Belongs to the bacterial solute-binding protein 9 family
AVR82_RS14920	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AVR82_RS14925	COG1121	(ABC) transporter
AVR82_RS14930	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
AVR82_RS14935	COG4977	sequence-specific DNA binding
AVR82_RS14935	COG1917	Cupin 2, conserved barrel domain protein
AVR82_RS14945	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
AVR82_RS14950	COG2151	metal-sulfur cluster biosynthetic enzyme
AVR82_RS14955	COG0471	metal ion transport
AVR82_RS14960	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
AVR82_RS14965	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
AVR82_RS14970	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
AVR82_RS14975	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
AVR82_RS14995	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
AVR82_RS15000	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
AVR82_RS15005	COG0101	tRNA pseudouridine synthase activity
AVR82_RS15015	COG1122	ATPase activity
AVR82_RS15020	COG1122	ATPase activity
AVR82_RS15030	COG4939	FMN-binding domain protein
AVR82_RS15055	COG0203	ribosomal protein L17
AVR82_RS15060	COG0202	RNA polymerase activity
AVR82_RS15065	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
AVR82_RS15070	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
AVR82_RS15075	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
AVR82_RS15080	COG0563	adenylate kinase activity
AVR82_RS15090	COG0200	Binds to the 23S rRNA
AVR82_RS15095	COG1841	ribosomal large subunit assembly
AVR82_RS15100	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
AVR82_RS15105	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
AVR82_RS15110	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
AVR82_RS15115	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
AVR82_RS15120	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
AVR82_RS15125	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
AVR82_RS15130	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
AVR82_RS15135	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
AVR82_RS15140	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
AVR82_RS15145	COG0255	Belongs to the universal ribosomal protein uL29 family
AVR82_RS15150	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
AVR82_RS15155	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
AVR82_RS15160	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
AVR82_RS15165	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
AVR82_RS15170	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
AVR82_RS15175	COG0089	rRNA binding
AVR82_RS15180	COG0088	Forms part of the polypeptide exit tunnel
AVR82_RS15185	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
AVR82_RS15190	COG0051	transcription antitermination factor activity, RNA binding
AVR82_RS15195	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
AVR82_RS15200	COG0049	tRNA binding
AVR82_RS15205	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
AVR82_RS15210	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
AVR82_RS15215	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
AVR82_RS15220	COG0085	RNA polymerase activity
AVR82_RS15230	COG0542	response to heat
AVR82_RS15235	COG4463	regulation of RNA biosynthetic process
AVR82_RS15275	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
AVR82_RS15280	COG1428	Deoxynucleoside kinase
AVR82_RS15290	COG0833	amino acid
AVR82_RS15295	COG0028	Belongs to the TPP enzyme family
AVR82_RS15300	COG1959	2 iron, 2 sulfur cluster binding
AVR82_RS15320	COG1316	TRANSCRIPTIONal
AVR82_RS15330	COG2966	Psort location CytoplasmicMembrane, score
AVR82_RS15335	COG1278	Cold shock
AVR82_RS15355	COG2814	Major facilitator Superfamily
AVR82_RS15385	COG0367	asparagine synthase
AVR82_RS15390	COG0527	aspartate kinase activity
AVR82_RS15395	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AVR82_RS15445	COG0640	Transcriptional regulator
AVR82_RS15450	COG0564	pseudouridine synthase activity
AVR82_RS15455	COG0514	ATP-dependent DNA helicase (RecQ)
AVR82_RS15475	COG4690	dipeptidase activity
AVR82_RS15480	COG2502	aspartate--ammonia ligase
AVR82_RS15485	COG0017	Asparaginyl-tRNA synthetase
AVR82_RS15490	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
AVR82_RS15500	COG1053	succinate dehydrogenase
AVR82_RS15505	COG0583	DNA-binding transcription factor activity
AVR82_RS15520	COG0572	uridine kinase
AVR82_RS15545	COG0308	aminopeptidase N
AVR82_RS15575	COG1302	Protein conserved in bacteria
AVR82_RS15590	COG2261	transglycosylase associated protein
AVR82_RS15595	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
AVR82_RS15595	COG2755	lipolytic protein G-D-S-L family
AVR82_RS15610	COG2814	Major facilitator Superfamily
AVR82_RS15615	COG1733	regulation of RNA biosynthetic process
AVR82_RS15620	COG1266	CAAX protease self-immunity
AVR82_RS15625	COG1396	sequence-specific DNA binding
AVR82_RS15665	COG0464	growth
AVR82_RS15670	COG0519	Catalyzes the synthesis of GMP from XMP
AVR82_RS15670	COG0518	GMP synthase (glutamine-hydrolyzing) activity
AVR82_RS15675	COG1072	(Pantothenic acid kinase))
AVR82_RS15680	COG2070	2-Nitropropane dioxygenase
AVR82_RS15685	COG3973	AAA domain
AVR82_RS15690	COG0586	Pfam SNARE associated Golgi protein
AVR82_RS15695	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
AVR82_RS15695	COG0456	acetyltransferase
AVR82_RS15700	COG0569	domain protein
AVR82_RS15700	COG0475	glutathione-regulated potassium exporter activity
AVR82_RS15705	COG0588	phosphoglycerate mutase activity
AVR82_RS15720	COG2076	Multidrug Resistance protein
AVR82_RS15730	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
AVR82_RS15760	COG1846	Transcriptional regulator
AVR82_RS15765	COG0531	amino acid
AVR82_RS15770	COG3394	polysaccharide catabolic process
AVR82_RS15775	COG1263	PTS System
AVR82_RS15775	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AVR82_RS15785	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AVR82_RS15785	COG1263	PTS System
AVR82_RS15785	COG2190	(PTS) system
AVR82_RS15790	COG0765	amino acid transport
AVR82_RS15795	COG0765	amino acid transport
AVR82_RS15800	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AVR82_RS15815	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AVR82_RS15820	COG0436	Aminotransferase
AVR82_RS15825	COG0546	phosphoglycolate phosphatase activity
AVR82_RS15840	COG0735	belongs to the Fur family
AVR82_RS15845	COG0194	GDP metabolic process
AVR82_RS15865	COG0531	amino acid
AVR82_RS15880	COG2936	dipeptidyl-peptidase activity
AVR82_RS15885	COG2755	lipolytic protein G-D-S-L family
AVR82_RS15885	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
AVR82_RS15895	COG2267	carboxylic ester hydrolase activity
AVR82_RS15900	COG0028	Belongs to the TPP enzyme family
AVR82_RS15905	COG0196	riboflavin kinase activity
AVR82_RS15910	COG0028	Belongs to the TPP enzyme family
AVR82_RS15915	COG2252	PERMEase
AVR82_RS15925	COG3475	LICD family
AVR82_RS15935	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
AVR82_RS15940	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
AVR82_RS15940	COG0248	Ppx GppA phosphatase
AVR82_RS15945	COG0477	Major facilitator Superfamily
AVR82_RS15960	COG1393	Belongs to the ArsC family
AVR82_RS15975	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
AVR82_RS15995	COG0778	Nitroreductase
AVR82_RS16010	COG2017	converts alpha-aldose to the beta-anomer
AVR82_RS16020	COG0561	phosphatase activity
AVR82_RS16030	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
AVR82_RS16035	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AVR82_RS16060	COG0025	NhaP-type Na H and K H
AVR82_RS16065	COG0812	UDP-N-acetylmuramate dehydrogenase activity
AVR82_RS16075	COG0708	Exodeoxyribonuclease III
AVR82_RS16090	COG0802	atpase or kinase
AVR82_RS16095	COG0280	phosphate acetyltransferase
AVR82_RS16100	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
AVR82_RS16105	COG0561	phosphatase activity
AVR82_RS16115	COG1126	abc transporter atp-binding protein
AVR82_RS16120	COG0765	amino acid transport
AVR82_RS16130	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
AVR82_RS16135	COG0557	exoribonuclease II activity
AVR82_RS16145	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
AVR82_RS16150	COG0038	chloride channel
AVR82_RS16160	COG0148	phosphopyruvate hydratase activity
AVR82_RS16165	COG0149	triose-phosphate isomerase activity
AVR82_RS16170	COG0126	phosphoglycerate kinase activity
AVR82_RS16180	COG2390	Transcriptional regulator
AVR82_RS16185	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
AVR82_RS16195	COG0740	serine-type endopeptidase activity
AVR82_RS16200	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AVR82_RS16210	COG1481	regulation of sporulation
AVR82_RS16220	COG1660	Displays ATPase and GTPase activities
AVR82_RS16230	COG0165	Argininosuccinate lyase
AVR82_RS16235	COG0137	argininosuccinate synthase activity
AVR82_RS16240	COG1854	S-ribosylhomocysteine lyase activity
AVR82_RS16245	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
AVR82_RS16250	COG0556	nucleotide-excision repair
AVR82_RS16260	COG2814	Major facilitator Superfamily
AVR82_RS16270	COG0446	pyridine nucleotide-disulphide oxidoreductase
AVR82_RS16320	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AVR82_RS16335	COG0860	N-Acetylmuramoyl-L-alanine amidase
AVR82_RS16340	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
AVR82_RS16345	COG0267	Belongs to the bacterial ribosomal protein bL33 family
AVR82_RS16355	COG1113	amino acid transport
AVR82_RS16365	COG1914	H( )-stimulated, divalent metal cation uptake system
AVR82_RS16385	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
AVR82_RS16420	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AVR82_RS16435	COG1192	Involved in chromosome partitioning
AVR82_RS16565	COG0542	response to heat
AVR82_RS16610	COG1418	mRNA catabolic process
AVR82_RS16615	COG0477	Major facilitator Superfamily
AVR82_RS16705	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
AVR82_RS16735	COG0446	pyridine nucleotide-disulphide oxidoreductase
AVR82_RS16745	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
AVR82_RS16920	COG0542	response to heat
AVR82_RS16960	COG1846	Transcriptional regulator
AVR82_RS17015	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AVR82_RS17025	COG1192	Involved in chromosome partitioning
AVR82_RS17190	COG3158	transport of potassium into the cell
AVR82_RS17240	COG2261	transglycosylase associated protein
AVR82_RS17250	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AVR82_RS17265	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AVR82_RS17355	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AVR82_RS17380	COG1215	transferase activity, transferring glycosyl groups
AVR82_RS17400	COG3158	transport of potassium into the cell
AVR82_RS17630	COG0230	Belongs to the bacterial ribosomal protein bL34 family
AVR82_RS17715	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
AVR82_RS18015	COG0333	Belongs to the bacterial ribosomal protein bL32 family
AVR82_RS18025	COG0267	Belongs to the bacterial ribosomal protein bL33 family
AVR82_RS18115	COG0257	Belongs to the bacterial ribosomal protein bL36 family
AVR82_RS18210	COG0333	Belongs to the bacterial ribosomal protein bL32 family
AVR82_RS18410	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
AVR82_RS18415	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection