locus-tag	class	description
EPJ55_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
EPJ55_RS00010	COG0592	DNA-directed DNA polymerase activity
EPJ55_RS00015	COG2501	S4 domain
EPJ55_RS00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
EPJ55_RS00025	COG0187	DNA topoisomerase II activity
EPJ55_RS00035	COG0360	Binds together with S18 to 16S ribosomal RNA
EPJ55_RS00040	COG0629	single-stranded DNA binding
EPJ55_RS00045	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
EPJ55_RS00055	COG0359	binds to the 23S rRNA
EPJ55_RS00060	COG0305	Participates in initiation and elongation during chromosome replication
EPJ55_RS00065	COG2814	Major facilitator Superfamily
EPJ55_RS00070	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
EPJ55_RS00075	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
EPJ55_RS00080	COG4166	transmembrane transport
EPJ55_RS00085	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
EPJ55_RS00090	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
EPJ55_RS00100	COG0297	glycogen (starch) synthase activity
EPJ55_RS00105	COG0058	SHG alpha-glucan phosphorylase activity
EPJ55_RS00110	COG3103	Sh3 type 3 domain protein
EPJ55_RS00110	COG0366	Alpha amylase catalytic
EPJ55_RS00125	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EPJ55_RS00130	COG1554	hydrolase, family 65, central catalytic
EPJ55_RS00140	COG1278	Cold shock
EPJ55_RS00155	COG0745	RESPONSE REGULATOR receiver
EPJ55_RS00160	COG5002	protein histidine kinase activity
EPJ55_RS00170	COG4853	Protein conserved in bacteria
EPJ55_RS00175	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
EPJ55_RS00180	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EPJ55_RS00185	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
EPJ55_RS00200	COG3586	endonuclease activity
EPJ55_RS00205	COG1573	uracil-dna glycosylase
EPJ55_RS00225	COG3976	FMN-binding domain protein
EPJ55_RS00225	COG1053	succinate dehydrogenase
EPJ55_RS00225	COG0431	NADPH-dependent FMN reductase
EPJ55_RS00230	COG0471	metal ion transport
EPJ55_RS00245	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
EPJ55_RS00250	COG1028	Short-chain dehydrogenase reductase Sdr
EPJ55_RS00260	COG0778	Nitroreductase
EPJ55_RS00265	COG2508	Transcriptional regulator
EPJ55_RS00270	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EPJ55_RS00275	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
EPJ55_RS00285	COG2365	Tyrosine phosphatase family
EPJ55_RS00290	COG2368	4-hydroxyphenylacetate
EPJ55_RS00310	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
EPJ55_RS00340	COG0604	alcohol dehydrogenase
EPJ55_RS00360	COG2267	carboxylic ester hydrolase activity
EPJ55_RS00365	COG3022	response to hydroperoxide
EPJ55_RS00375	COG4166	transmembrane transport
EPJ55_RS00400	COG1122	ATPase activity
EPJ55_RS00405	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
EPJ55_RS00410	COG0310	cobalt ion transport
EPJ55_RS00415	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EPJ55_RS00420	COG3875	lactate racemase activity
EPJ55_RS00425	COG1691	(AIR) carboxylase
EPJ55_RS00430	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
EPJ55_RS00435	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
EPJ55_RS00440	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
EPJ55_RS00445	COG1606	tRNA processing
EPJ55_RS00455	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
EPJ55_RS00460	COG0351	phosphomethylpyrimidine kinase
EPJ55_RS00465	COG0352	thiamine-phosphate diphosphorylase activity
EPJ55_RS00475	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
EPJ55_RS00490	COG1113	amino acid transport
EPJ55_RS00500	COG2267	carboxylic ester hydrolase activity
EPJ55_RS00505	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
EPJ55_RS00515	COG1983	PspC domain protein
EPJ55_RS00545	COG0640	Transcriptional regulator
EPJ55_RS00550	COG2807	transmembrane transport
EPJ55_RS00555	COG0656	L-ascorbic acid biosynthetic process
EPJ55_RS00560	COG0667	Aldo Keto reductase
EPJ55_RS00590	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
EPJ55_RS00595	COG1122	ATPase activity
EPJ55_RS00600	COG4720	Psort location CytoplasmicMembrane, score
EPJ55_RS00610	COG2188	Transcriptional regulator
EPJ55_RS00635	COG1028	Short-chain dehydrogenase reductase Sdr
EPJ55_RS00640	COG1131	(ABC) transporter
EPJ55_RS00655	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
EPJ55_RS00660	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
EPJ55_RS00665	COG1309	transcriptional regulator
EPJ55_RS00670	COG2376	Dihydroxyacetone kinase
EPJ55_RS00675	COG2376	Dihydroxyacetone kinase
EPJ55_RS00680	COG1461	Dihydroxyacetone kinase
EPJ55_RS00685	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
EPJ55_RS00690	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
EPJ55_RS00695	COG1609	Transcriptional regulator
EPJ55_RS00700	COG1609	Transcriptional regulator
EPJ55_RS00705	COG0366	Alpha amylase catalytic
EPJ55_RS00710	COG2182	Extracellular solute-binding protein
EPJ55_RS00715	COG1175	transmembrane transport
EPJ55_RS00720	COG3833	ABC-type maltose transport systems, permease component
EPJ55_RS00735	COG3842	ATPase activity
EPJ55_RS00790	COG1757	Na H antiporter
EPJ55_RS00820	COG4166	transmembrane transport
EPJ55_RS00825	COG4166	transmembrane transport
EPJ55_RS00835	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
EPJ55_RS00840	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
EPJ55_RS00845	COG0406	alpha-ribazole phosphatase activity
EPJ55_RS00850	COG0667	Aldo Keto reductase
EPJ55_RS00880	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
EPJ55_RS00885	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
EPJ55_RS00890	COG0488	(ABC) transporter
EPJ55_RS00900	COG4172	Belongs to the ABC transporter superfamily
EPJ55_RS00910	COG0386	Belongs to the glutathione peroxidase family
EPJ55_RS00920	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
EPJ55_RS00935	COG0363	glucosamine-6-phosphate deaminase activity
EPJ55_RS00945	COG2213	PTS system mannitol-specific
EPJ55_RS00955	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
EPJ55_RS00960	COG0246	Mannitol dehydrogenase
EPJ55_RS00970	COG3118	belongs to the thioredoxin family
EPJ55_RS01000	COG0431	NADPH-dependent FMN reductase
EPJ55_RS01005	COG1045	serine acetyltransferase
EPJ55_RS01010	COG0626	cystathionine gamma-synthase activity
EPJ55_RS01015	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
EPJ55_RS01040	COG2188	Transcriptional regulator
EPJ55_RS01055	COG1263	PTS System
EPJ55_RS01055	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EPJ55_RS01055	COG2190	(PTS) system
EPJ55_RS01065	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
EPJ55_RS01070	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
EPJ55_RS01075	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
EPJ55_RS01085	COG0163	prenyltransferase activity
EPJ55_RS01110	COG1959	2 iron, 2 sulfur cluster binding
EPJ55_RS01115	COG1309	transcriptional regulator
EPJ55_RS01120	COG1914	H( )-stimulated, divalent metal cation uptake system
EPJ55_RS01140	COG2814	Major facilitator Superfamily
EPJ55_RS01155	COG0745	RESPONSE REGULATOR receiver
EPJ55_RS01170	COG1737	Transcriptional regulator
EPJ55_RS01175	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EPJ55_RS01190	COG1316	TRANSCRIPTIONal
EPJ55_RS01205	COG2357	RelA SpoT domain protein
EPJ55_RS01215	COG2409	Drug exporters of the RND superfamily
EPJ55_RS01215	COG1033	growth of symbiont in host cell
EPJ55_RS01215	COG2409	Drug exporters of the RND superfamily
EPJ55_RS01215	COG1033	growth of symbiont in host cell
EPJ55_RS01220	COG2818	Glycosylase
EPJ55_RS01230	COG0577	efflux transmembrane transporter activity
EPJ55_RS01235	COG1136	(ABC) transporter
EPJ55_RS01250	COG0741	lytic transglycosylase activity
EPJ55_RS01255	COG1388	LysM domain
EPJ55_RS01255	COG3942	CHAP domain
EPJ55_RS01285	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
EPJ55_RS01295	COG1846	Transcriptional regulator
EPJ55_RS01300	COG1252	NADH dehydrogenase
EPJ55_RS01325	COG3842	ATPase activity
EPJ55_RS01355	COG1725	Transcriptional regulator
EPJ55_RS01360	COG1131	(ABC) transporter
EPJ55_RS01370	COG1454	alcohol dehydrogenase
EPJ55_RS01370	COG1012	belongs to the aldehyde dehydrogenase family
EPJ55_RS01405	COG1268	BioY protein
EPJ55_RS01430	COG2011	ABC-type metal ion transport system permease component
EPJ55_RS01435	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
EPJ55_RS01440	COG0436	Aminotransferase
EPJ55_RS01450	COG1682	transport, permease protein
EPJ55_RS01455	COG1134	teichoic acid transport
EPJ55_RS01470	COG2814	Major facilitator Superfamily
EPJ55_RS01475	COG0004	ammonium transporteR
EPJ55_RS01495	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
EPJ55_RS01505	COG3759	membrane
EPJ55_RS01510	COG1881	PFAM PEBP family protein
EPJ55_RS01540	COG0300	oxidoreductase activity
EPJ55_RS01555	COG1125	glycine betaine transport
EPJ55_RS01565	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
EPJ55_RS01575	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
EPJ55_RS01675	COG3279	Response regulator of the LytR AlgR family
EPJ55_RS01710	COG2274	protein secretion by the type I secretion system
EPJ55_RS01745	COG3973	AAA domain
EPJ55_RS01750	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EPJ55_RS01755	COG0180	Tryptophanyl-tRNA synthetase
EPJ55_RS01760	COG2188	Transcriptional regulator
EPJ55_RS01770	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EPJ55_RS01785	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EPJ55_RS01790	COG2723	6-phospho-beta-galactosidase activity
EPJ55_RS01795	COG1940	carbohydrate kinase activity
EPJ55_RS01805	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EPJ55_RS01810	COG0248	Ppx GppA phosphatase
EPJ55_RS01825	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
EPJ55_RS01830	COG1801	Protein of unknown function DUF72
EPJ55_RS01840	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EPJ55_RS01840	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EPJ55_RS01845	COG2814	Major facilitator Superfamily
EPJ55_RS01850	COG0084	hydrolase, TatD family'
EPJ55_RS01855	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
EPJ55_RS01860	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
EPJ55_RS01865	COG4466	Protein conserved in bacteria
EPJ55_RS01870	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
EPJ55_RS01875	COG1073	alpha beta
EPJ55_RS01880	COG1121	(ABC) transporter
EPJ55_RS01885	COG1321	iron dependent repressor
EPJ55_RS01885	COG1108	ABC-type Mn2 Zn2 transport systems permease components
EPJ55_RS01890	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
EPJ55_RS01895	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
EPJ55_RS01905	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
EPJ55_RS01925	COG1078	dGTPase activity
EPJ55_RS01930	COG0095	Lipoate-protein ligase
EPJ55_RS01940	COG3343	RNA polymerase activity
EPJ55_RS01945	COG0504	CTP synthase activity
EPJ55_RS01950	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
EPJ55_RS01955	COG0814	amino acid
EPJ55_RS01960	COG1760	l-serine dehydratase
EPJ55_RS01965	COG1760	l-serine dehydratase
EPJ55_RS01980	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
EPJ55_RS01985	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
EPJ55_RS01990	COG0254	rRNA binding
EPJ55_RS02000	COG3764	Sortase (surface protein transpeptidase)
EPJ55_RS02005	COG1704	LemA family
EPJ55_RS02010	COG0501	Belongs to the peptidase M48B family
EPJ55_RS02020	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
EPJ55_RS02030	COG0736	holo-[acyl-carrier-protein] synthase activity
EPJ55_RS02035	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
EPJ55_RS02040	COG2337	Toxic component of a toxin-antitoxin (TA) module
EPJ55_RS02045	COG3158	transport of potassium into the cell
EPJ55_RS02060	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
EPJ55_RS02065	COG0505	Belongs to the CarA family
EPJ55_RS02070	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
EPJ55_RS02075	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
EPJ55_RS02080	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
EPJ55_RS02085	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
EPJ55_RS02090	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
EPJ55_RS02110	COG0039	L-malate dehydrogenase activity
EPJ55_RS02115	COG0193	aminoacyl-tRNA hydrolase activity
EPJ55_RS02120	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
EPJ55_RS02125	COG2244	polysaccharide biosynthetic process
EPJ55_RS02130	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
EPJ55_RS02140	COG1098	S1 RNA binding domain
EPJ55_RS02145	COG0037	tRNA processing
EPJ55_RS02160	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
EPJ55_RS02165	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EPJ55_RS02170	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
EPJ55_RS02210	COG3104	oligopeptide transport
EPJ55_RS02260	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EPJ55_RS02270	COG2188	Transcriptional regulator
EPJ55_RS02280	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
EPJ55_RS02285	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
EPJ55_RS02300	COG2183	response to ionizing radiation
EPJ55_RS02305	COG3091	SprT-like family
EPJ55_RS02310	COG0460	homoserine dehydrogenase
EPJ55_RS02315	COG0083	homoserine kinase activity
EPJ55_RS02335	COG3715	PTS system
EPJ55_RS02340	COG3716	PTS system mannose fructose sorbose family IID component
EPJ55_RS02350	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
EPJ55_RS02350	COG3933	PFAM sigma-54 factor interaction domain-containing protein
EPJ55_RS02355	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EPJ55_RS02355	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
EPJ55_RS02360	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
EPJ55_RS02360	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EPJ55_RS02365	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EPJ55_RS02375	COG0439	Biotin carboxylase
EPJ55_RS02385	COG0825	malonyl-CoA metabolic process
EPJ55_RS02390	COG1316	TRANSCRIPTIONal
EPJ55_RS02400	COG0697	spore germination
EPJ55_RS02405	COG0588	phosphoglycerate mutase activity
EPJ55_RS02420	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
EPJ55_RS02430	COG0756	dUTP diphosphatase activity
EPJ55_RS02440	COG4956	integral membrane protein (PIN domain superfamily)
EPJ55_RS02445	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
EPJ55_RS02450	COG0215	cysteine-tRNA ligase activity
EPJ55_RS02455	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
EPJ55_RS02475	COG0267	Belongs to the bacterial ribosomal protein bL33 family
EPJ55_RS02485	COG0250	Participates in transcription elongation, termination and antitermination
EPJ55_RS02495	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
EPJ55_RS02500	COG0081	regulation of translation
EPJ55_RS02505	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
EPJ55_RS02510	COG0222	ribosome binding
EPJ55_RS02535	COG1611	Belongs to the LOG family
EPJ55_RS02545	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EPJ55_RS02550	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
EPJ55_RS02555	COG2813	Specifically methylates the guanine in position
EPJ55_RS02570	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
EPJ55_RS02575	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
EPJ55_RS02580	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
EPJ55_RS02590	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
EPJ55_RS02595	COG3870	Protein conserved in bacteria
EPJ55_RS02600	COG0470	DNA polymerase III
EPJ55_RS02605	COG4467	Involved in initiation control of chromosome replication
EPJ55_RS02620	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
EPJ55_RS02630	COG3639	organic phosphonate transmembrane transporter activity
EPJ55_RS02640	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
EPJ55_RS02650	COG1214	PFAM Peptidase M22, glycoprotease
EPJ55_RS02655	COG0456	acetyltransferase
EPJ55_RS02660	COG0456	acetyltransferase
EPJ55_RS02665	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
EPJ55_RS02670	COG0488	(ABC) transporter
EPJ55_RS02675	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
EPJ55_RS02685	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
EPJ55_RS02690	COG0459	protein refolding
EPJ55_RS02695	COG0531	amino acid
EPJ55_RS02700	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EPJ55_RS02705	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
EPJ55_RS02710	COG1739	Uncharacterized protein family UPF0029
EPJ55_RS02715	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
EPJ55_RS02730	COG0653	protein targeting
EPJ55_RS02745	COG0745	RESPONSE REGULATOR receiver
EPJ55_RS02750	COG5002	protein histidine kinase activity
EPJ55_RS02760	COG0573	inorganic phosphate transmembrane transporter activity
EPJ55_RS02765	COG0581	inorganic phosphate transmembrane transporter activity
EPJ55_RS02770	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
EPJ55_RS02775	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
EPJ55_RS02780	COG0704	Plays a role in the regulation of phosphate uptake
EPJ55_RS02785	COG1983	PspC domain protein
EPJ55_RS02790	COG1950	PFAM Membrane protein of
EPJ55_RS02795	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
EPJ55_RS02800	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
EPJ55_RS02805	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
EPJ55_RS02810	COG1210	Utp--glucose-1-phosphate uridylyltransferase
EPJ55_RS02820	COG0446	pyridine nucleotide-disulphide oxidoreductase
EPJ55_RS02825	COG0492	ferredoxin-NADP+ reductase activity
EPJ55_RS02830	COG2323	membrane
EPJ55_RS02840	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EPJ55_RS02850	COG0446	pyridine nucleotide-disulphide oxidoreductase
EPJ55_RS02860	COG2814	Major facilitator Superfamily
EPJ55_RS02870	COG0556	nucleotide-excision repair
EPJ55_RS02875	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
EPJ55_RS02880	COG1854	S-ribosylhomocysteine lyase activity
EPJ55_RS02885	COG0137	argininosuccinate synthase activity
EPJ55_RS02890	COG0165	Argininosuccinate lyase
EPJ55_RS02900	COG1660	Displays ATPase and GTPase activities
EPJ55_RS02905	COG0391	Required for morphogenesis under gluconeogenic growth conditions
EPJ55_RS02910	COG1481	regulation of sporulation
EPJ55_RS02920	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EPJ55_RS02925	COG0740	serine-type endopeptidase activity
EPJ55_RS02935	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
EPJ55_RS02940	COG2390	Transcriptional regulator
EPJ55_RS02950	COG0126	phosphoglycerate kinase activity
EPJ55_RS02955	COG0149	triose-phosphate isomerase activity
EPJ55_RS02960	COG0148	phosphopyruvate hydratase activity
EPJ55_RS02970	COG0038	chloride channel
EPJ55_RS02975	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
EPJ55_RS02985	COG0557	exoribonuclease II activity
EPJ55_RS02990	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
EPJ55_RS03000	COG0765	amino acid transport
EPJ55_RS03005	COG1126	abc transporter atp-binding protein
EPJ55_RS03015	COG0561	phosphatase activity
EPJ55_RS03020	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
EPJ55_RS03025	COG0280	phosphate acetyltransferase
EPJ55_RS03030	COG0802	atpase or kinase
EPJ55_RS03045	COG0708	Exodeoxyribonuclease III
EPJ55_RS03055	COG0812	UDP-N-acetylmuramate dehydrogenase activity
EPJ55_RS03060	COG0025	NhaP-type Na H and K H
EPJ55_RS03085	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EPJ55_RS03090	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
EPJ55_RS03100	COG0561	phosphatase activity
EPJ55_RS03110	COG2017	converts alpha-aldose to the beta-anomer
EPJ55_RS03125	COG0778	Nitroreductase
EPJ55_RS03135	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
EPJ55_RS03150	COG1393	Belongs to the ArsC family
EPJ55_RS03165	COG0477	Major facilitator Superfamily
EPJ55_RS03170	COG0248	Ppx GppA phosphatase
EPJ55_RS03175	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
EPJ55_RS03190	COG3475	LICD family
EPJ55_RS03205	COG2252	PERMEase
EPJ55_RS03210	COG0028	Belongs to the TPP enzyme family
EPJ55_RS03215	COG0196	riboflavin kinase activity
EPJ55_RS03220	COG0028	Belongs to the TPP enzyme family
EPJ55_RS03225	COG2267	carboxylic ester hydrolase activity
EPJ55_RS03235	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
EPJ55_RS03235	COG2755	lipolytic protein G-D-S-L family
EPJ55_RS03240	COG2936	dipeptidyl-peptidase activity
EPJ55_RS03255	COG0531	amino acid
EPJ55_RS03280	COG0194	GDP metabolic process
EPJ55_RS03285	COG0735	belongs to the Fur family
EPJ55_RS03300	COG0546	phosphoglycolate phosphatase activity
EPJ55_RS03305	COG0436	Aminotransferase
EPJ55_RS03310	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EPJ55_RS03325	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EPJ55_RS03330	COG0765	amino acid transport
EPJ55_RS03335	COG0765	amino acid transport
EPJ55_RS03340	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EPJ55_RS03340	COG1263	PTS System
EPJ55_RS03340	COG2190	(PTS) system
EPJ55_RS03350	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EPJ55_RS03350	COG1263	PTS System
EPJ55_RS03355	COG3394	polysaccharide catabolic process
EPJ55_RS03360	COG0531	amino acid
EPJ55_RS03365	COG1846	Transcriptional regulator
EPJ55_RS03395	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
EPJ55_RS03405	COG2076	Multidrug Resistance protein
EPJ55_RS03420	COG0588	phosphoglycerate mutase activity
EPJ55_RS03425	COG0475	glutathione-regulated potassium exporter activity
EPJ55_RS03425	COG0569	domain protein
EPJ55_RS03430	COG0456	acetyltransferase
EPJ55_RS03430	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
EPJ55_RS03435	COG3711	transcriptional antiterminator
EPJ55_RS03440	COG1263	PTS System
EPJ55_RS03440	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EPJ55_RS03440	COG2190	(PTS) system
EPJ55_RS03445	COG2723	6-phospho-beta-galactosidase activity
EPJ55_RS03450	COG0586	Pfam SNARE associated Golgi protein
EPJ55_RS03455	COG3973	AAA domain
EPJ55_RS03460	COG2070	2-Nitropropane dioxygenase
EPJ55_RS03465	COG1072	(Pantothenic acid kinase))
EPJ55_RS03470	COG0518	GMP synthase (glutamine-hydrolyzing) activity
EPJ55_RS03470	COG0519	Catalyzes the synthesis of GMP from XMP
EPJ55_RS03480	COG2826	transposase and inactivated derivatives, IS30 family
EPJ55_RS03485	COG1396	sequence-specific DNA binding
EPJ55_RS03495	COG1266	CAAX protease self-immunity
EPJ55_RS03535	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
EPJ55_RS03535	COG2755	lipolytic protein G-D-S-L family
EPJ55_RS03540	COG2261	transglycosylase associated protein
EPJ55_RS03555	COG1302	Protein conserved in bacteria
EPJ55_RS03585	COG0308	aminopeptidase N
EPJ55_RS03615	COG0572	uridine kinase
EPJ55_RS03630	COG0583	DNA-binding transcription factor activity
EPJ55_RS03635	COG1053	succinate dehydrogenase
EPJ55_RS03645	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
EPJ55_RS03650	COG0017	Asparaginyl-tRNA synthetase
EPJ55_RS03655	COG2502	aspartate--ammonia ligase
EPJ55_RS03660	COG4690	dipeptidase activity
EPJ55_RS03680	COG0514	ATP-dependent DNA helicase (RecQ)
EPJ55_RS03685	COG0564	pseudouridine synthase activity
EPJ55_RS03740	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
EPJ55_RS03745	COG0527	aspartate kinase activity
EPJ55_RS03750	COG0367	asparagine synthase
EPJ55_RS03780	COG2814	Major facilitator Superfamily
EPJ55_RS03800	COG1278	Cold shock
EPJ55_RS03805	COG2966	Psort location CytoplasmicMembrane, score
EPJ55_RS03815	COG1316	TRANSCRIPTIONal
EPJ55_RS03835	COG1959	2 iron, 2 sulfur cluster binding
EPJ55_RS03840	COG0028	Belongs to the TPP enzyme family
EPJ55_RS03845	COG0833	amino acid
EPJ55_RS03855	COG1428	Deoxynucleoside kinase
EPJ55_RS03860	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
EPJ55_RS03900	COG4463	regulation of RNA biosynthetic process
EPJ55_RS03905	COG0542	response to heat
EPJ55_RS03920	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
EPJ55_RS03925	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
EPJ55_RS03930	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
EPJ55_RS03935	COG0049	tRNA binding
EPJ55_RS03940	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
EPJ55_RS03945	COG0051	transcription antitermination factor activity, RNA binding
EPJ55_RS03950	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
EPJ55_RS03955	COG0088	Forms part of the polypeptide exit tunnel
EPJ55_RS03960	COG0089	rRNA binding
EPJ55_RS03965	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
EPJ55_RS03970	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
EPJ55_RS03975	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
EPJ55_RS03980	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
EPJ55_RS03985	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
EPJ55_RS03990	COG0255	Belongs to the universal ribosomal protein uL29 family
EPJ55_RS03995	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
EPJ55_RS04000	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
EPJ55_RS04005	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
EPJ55_RS04010	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
EPJ55_RS04015	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
EPJ55_RS04020	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
EPJ55_RS04025	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
EPJ55_RS04030	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
EPJ55_RS04035	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
EPJ55_RS04040	COG1841	ribosomal large subunit assembly
EPJ55_RS04045	COG0200	Binds to the 23S rRNA
EPJ55_RS04055	COG0563	adenylate kinase activity
EPJ55_RS04060	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
EPJ55_RS04065	COG0257	Belongs to the bacterial ribosomal protein bL36 family
EPJ55_RS04070	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
EPJ55_RS04075	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
EPJ55_RS04080	COG0202	RNA polymerase activity
EPJ55_RS04085	COG0203	ribosomal protein L17
EPJ55_RS04090	COG0142	geranyltranstransferase activity
EPJ55_RS04110	COG4939	FMN-binding domain protein
EPJ55_RS04120	COG1122	ATPase activity
EPJ55_RS04125	COG1122	ATPase activity
EPJ55_RS04135	COG0101	tRNA pseudouridine synthase activity
EPJ55_RS04140	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
EPJ55_RS04145	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
EPJ55_RS04165	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
EPJ55_RS04170	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
EPJ55_RS04175	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
EPJ55_RS04185	COG0471	metal ion transport
EPJ55_RS04190	COG2151	metal-sulfur cluster biosynthetic enzyme
EPJ55_RS04195	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
EPJ55_RS04205	COG1917	Cupin 2, conserved barrel domain protein
EPJ55_RS04205	COG4977	sequence-specific DNA binding
EPJ55_RS04210	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
EPJ55_RS04215	COG1121	(ABC) transporter
EPJ55_RS04220	COG1108	ABC-type Mn2 Zn2 transport systems permease components
EPJ55_RS04225	COG0803	Belongs to the bacterial solute-binding protein 9 family
EPJ55_RS04235	COG0039	L-malate dehydrogenase activity
EPJ55_RS04240	COG0471	metal ion transport
EPJ55_RS04260	COG3052	prosthetic group binding
EPJ55_RS04280	COG0114	fumarate hydratase activity
EPJ55_RS04285	COG1053	succinate dehydrogenase
EPJ55_RS04295	COG0583	DNA-binding transcription factor activity
EPJ55_RS04300	COG0583	DNA-binding transcription factor activity
EPJ55_RS04305	COG0281	malic enzyme
EPJ55_RS04315	COG0531	amino acid
EPJ55_RS04320	COG4684	Psort location CytoplasmicMembrane, score
EPJ55_RS04335	COG1271	oxidase subunit
EPJ55_RS04340	COG1294	oxidase, subunit
EPJ55_RS04345	COG4988	ABC transporter
EPJ55_RS04350	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
EPJ55_RS04360	COG0142	geranyltranstransferase activity
EPJ55_RS04375	COG1705	Flagellar rod assembly protein muramidase FlgJ
EPJ55_RS04380	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
EPJ55_RS04385	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
EPJ55_RS04390	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
EPJ55_RS04400	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
EPJ55_RS04405	COG4851	CamS sex pheromone cAM373 precursor
EPJ55_RS04410	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
EPJ55_RS04415	COG0154	amidase activity
EPJ55_RS04420	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
EPJ55_RS04425	COG1597	lipid kinase activity
EPJ55_RS04430	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
EPJ55_RS04445	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EPJ55_RS04455	COG1737	Transcriptional regulator
EPJ55_RS04470	COG1278	Cold shock
EPJ55_RS04475	COG0673	inositol 2-dehydrogenase activity
EPJ55_RS04480	COG0513	Belongs to the DEAD box helicase family
EPJ55_RS04495	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EPJ55_RS04520	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
EPJ55_RS04530	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
EPJ55_RS04540	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
EPJ55_RS04550	COG0562	UDP-galactopyranose mutase
EPJ55_RS04595	COG2244	polysaccharide biosynthetic process
EPJ55_RS04600	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
EPJ55_RS04610	COG1088	dTDP-glucose 4,6-dehydratase activity
EPJ55_RS04615	COG0582	viral genome integration into host DNA
EPJ55_RS04625	COG0489	protein tyrosine kinase activity
EPJ55_RS04630	COG4464	protein tyrosine phosphatase activity
EPJ55_RS04640	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
EPJ55_RS04660	COG1215	transferase activity, transferring glycosyl groups
EPJ55_RS04665	COG5039	Polysaccharide pyruvyl transferase
EPJ55_RS04755	COG0562	UDP-galactopyranose mutase
EPJ55_RS04790	COG2207	Transcriptional regulator
EPJ55_RS04790	COG1609	Transcriptional regulator
EPJ55_RS04810	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
EPJ55_RS04845	COG2137	regulation of response to DNA damage stimulus
EPJ55_RS04850	COG3557	Belongs to the UPF0374 family
EPJ55_RS04875	COG0628	permease
EPJ55_RS04880	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
EPJ55_RS04885	COG2610	gluconate transmembrane transporter activity
EPJ55_RS04890	COG1070	Carbohydrate kinase
EPJ55_RS04895	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
EPJ55_RS04900	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EPJ55_RS04905	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
EPJ55_RS04935	COG4166	transmembrane transport
EPJ55_RS04940	COG0601	transmembrane transport
EPJ55_RS04945	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EPJ55_RS04950	COG0444	Belongs to the ABC transporter superfamily
EPJ55_RS04955	COG4608	Belongs to the ABC transporter superfamily
EPJ55_RS04965	COG0582	viral genome integration into host DNA
EPJ55_RS04970	COG0542	response to heat
EPJ55_RS04990	COG0438	transferase activity, transferring glycosyl groups
EPJ55_RS04995	COG0438	transferase activity, transferring glycosyl groups
EPJ55_RS05005	COG1686	Belongs to the peptidase S11 family
EPJ55_RS05010	COG0436	Aminotransferase
EPJ55_RS05015	COG4703	Protein of unknown function (DUF1797)
EPJ55_RS05020	COG1368	sulfuric ester hydrolase activity
EPJ55_RS05105	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
EPJ55_RS05125	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
EPJ55_RS05130	COG2207	Transcriptional regulator
EPJ55_RS05130	COG4753	response regulator
EPJ55_RS05145	COG1940	carbohydrate kinase activity
EPJ55_RS05155	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
EPJ55_RS05160	COG0833	amino acid
EPJ55_RS05165	COG2040	homocysteine
EPJ55_RS05170	COG0438	transferase activity, transferring glycosyl groups
EPJ55_RS05180	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
EPJ55_RS05185	COG0477	Major facilitator Superfamily
EPJ55_RS05200	COG0438	transferase activity, transferring glycosyl groups
EPJ55_RS05215	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
EPJ55_RS05225	COG0495	leucyl-tRNA aminoacylation
EPJ55_RS05230	COG2244	polysaccharide biosynthetic process
EPJ55_RS05235	COG1187	pseudouridine synthase activity
EPJ55_RS05240	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
EPJ55_RS05245	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EPJ55_RS05255	COG3842	ATPase activity
EPJ55_RS05260	COG1175	transmembrane transport
EPJ55_RS05265	COG0395	ABC-type sugar transport system, permease component
EPJ55_RS05275	COG0584	glycerophosphoryl diester phosphodiesterase
EPJ55_RS05280	COG1428	Deoxynucleoside kinase
EPJ55_RS05285	COG1970	mechanosensitive ion channel activity
EPJ55_RS05320	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EPJ55_RS05325	COG0789	Transcriptional regulator
EPJ55_RS05335	COG0697	spore germination
EPJ55_RS05340	COG0561	phosphatase activity
EPJ55_RS05355	COG3279	Response regulator of the LytR AlgR family
EPJ55_RS05375	COG1846	Transcriptional regulator
EPJ55_RS05390	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
EPJ55_RS05425	COG0646	methionine synthase
EPJ55_RS05425	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
EPJ55_RS05430	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
EPJ55_RS05440	COG2046	Belongs to the sulfate adenylyltransferase family
EPJ55_RS05445	COG0529	Catalyzes the synthesis of activated sulfate
EPJ55_RS05450	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
EPJ55_RS05460	COG0471	metal ion transport
EPJ55_RS05460	COG3273	potassium ion transport
EPJ55_RS05465	COG0534	Mate efflux family protein
EPJ55_RS05485	COG2153	protein acetylation
EPJ55_RS05490	COG0018	arginyl-trna synthetase
EPJ55_RS05500	COG0577	efflux transmembrane transporter activity
EPJ55_RS05500	COG1136	(ABC) transporter
EPJ55_RS05515	COG1376	ErfK ybiS ycfS ynhG family protein
EPJ55_RS05520	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EPJ55_RS05525	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EPJ55_RS05535	COG0436	Aminotransferase
EPJ55_RS05540	COG1438	arginine binding
EPJ55_RS05545	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EPJ55_RS05550	COG3679	Belongs to the UPF0342 family
EPJ55_RS05555	COG0420	3'-5' exonuclease activity
EPJ55_RS05560	COG4717	serine-type aminopeptidase activity
EPJ55_RS05565	COG3481	metal-dependent phosphohydrolase, HD sub domain
EPJ55_RS05580	COG0583	DNA-binding transcription factor activity
EPJ55_RS05590	COG1053	succinate dehydrogenase
EPJ55_RS05590	COG0431	NADPH-dependent FMN reductase
EPJ55_RS05590	COG3976	FMN-binding domain protein
EPJ55_RS05610	COG0463	Glycosyl transferase, family 2
EPJ55_RS05630	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EPJ55_RS05630	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EPJ55_RS05635	COG0307	riboflavin synthase, alpha
EPJ55_RS05640	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
EPJ55_RS05640	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
EPJ55_RS05645	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
EPJ55_RS05670	COG0446	pyridine nucleotide-disulphide oxidoreductase
EPJ55_RS05700	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EPJ55_RS05710	COG0537	adenosine 5'-monophosphoramidase activity
EPJ55_RS05715	COG1131	(ABC) transporter
EPJ55_RS05720	COG4473	ABC transporter
EPJ55_RS05725	COG0510	thiamine kinase activity
EPJ55_RS05730	COG0220	tRNA (guanine-N7-)-methyltransferase activity
EPJ55_RS05740	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EPJ55_RS05745	COG1674	ftsk spoiiie
EPJ55_RS05750	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
EPJ55_RS05775	COG0719	Fe-S assembly protein
EPJ55_RS05780	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
EPJ55_RS05790	COG0719	Fe-S assembly protein
EPJ55_RS05800	COG1120	ATPase activity
EPJ55_RS05805	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EPJ55_RS05810	COG0716	FMN binding
EPJ55_RS05825	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
EPJ55_RS05830	COG2223	nitrite transmembrane transporter activity
EPJ55_RS05835	COG2151	metal-sulfur cluster biosynthetic enzyme
EPJ55_RS05890	COG0315	cyclic pyranopterin monophosphate synthase activity
EPJ55_RS05895	COG1763	Mo-molybdopterin cofactor biosynthetic process
EPJ55_RS05900	COG0303	'Molybdopterin
EPJ55_RS05910	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
EPJ55_RS05915	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
EPJ55_RS05920	COG1140	nitrate reductase beta subunit
EPJ55_RS05930	COG2181	nitrate reductase activity
EPJ55_RS05950	COG3655	Transcriptional regulator
EPJ55_RS05960	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EPJ55_RS05960	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EPJ55_RS05965	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
EPJ55_RS05970	COG0237	dephospho-CoA kinase activity
EPJ55_RS05975	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
EPJ55_RS05980	COG3611	Membrane attachment protein
EPJ55_RS05985	COG1484	DNA-dependent DNA replication
EPJ55_RS05990	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
EPJ55_RS05995	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
EPJ55_RS06000	COG0291	Belongs to the bacterial ribosomal protein bL35 family
EPJ55_RS06005	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
EPJ55_RS06015	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
EPJ55_RS06020	COG0604	alcohol dehydrogenase
EPJ55_RS06025	COG1733	regulation of RNA biosynthetic process
EPJ55_RS06035	COG1215	transferase activity, transferring glycosyl groups
EPJ55_RS06055	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
EPJ55_RS06060	COG1534	Rna-binding protein
EPJ55_RS06065	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
EPJ55_RS06070	COG1713	HD superfamily hydrolase involved in NAD metabolism
EPJ55_RS06075	COG0799	negative regulation of ribosome biogenesis
EPJ55_RS06080	COG2226	methyltransferase
EPJ55_RS06085	COG1323	Belongs to the UPF0348 family
EPJ55_RS06095	COG0333	Belongs to the bacterial ribosomal protein bL32 family
EPJ55_RS06110	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
EPJ55_RS06115	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
EPJ55_RS06120	COG0745	RESPONSE REGULATOR receiver
EPJ55_RS06125	COG5002	protein histidine kinase activity
EPJ55_RS06135	COG0419	ATPase involved in DNA repair
EPJ55_RS06155	COG1254	Belongs to the acylphosphatase family
EPJ55_RS06160	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EPJ55_RS06170	COG1733	regulation of RNA biosynthetic process
EPJ55_RS06175	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
EPJ55_RS06180	COG0072	phenylalanine-tRNA ligase activity
EPJ55_RS06180	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EPJ55_RS06185	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
EPJ55_RS06190	COG0572	uridine kinase
EPJ55_RS06195	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
EPJ55_RS06210	COG4841	protein insertion into membrane
EPJ55_RS06220	COG0768	penicillin binding
EPJ55_RS06225	COG0267	Belongs to the bacterial ribosomal protein bL33 family
EPJ55_RS06230	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
EPJ55_RS06235	COG0457	Tetratricopeptide repeat
EPJ55_RS06235	COG0705	Rhomboid family
EPJ55_RS06245	COG1940	carbohydrate kinase activity
EPJ55_RS06265	COG0584	glycerophosphoryl diester phosphodiesterase
EPJ55_RS06270	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
EPJ55_RS06275	COG0789	Transcriptional regulator
EPJ55_RS06325	COG0261	This protein binds to 23S rRNA in the presence of protein L20
EPJ55_RS06335	COG0211	Belongs to the bacterial ribosomal protein bL27 family
EPJ55_RS06340	COG0006	proline dipeptidase activity
EPJ55_RS06345	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
EPJ55_RS06350	COG1302	Protein conserved in bacteria
EPJ55_RS06355	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EPJ55_RS06360	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
EPJ55_RS06365	COG1570	exodeoxyribonuclease VII activity
EPJ55_RS06370	COG1722	exodeoxyribonuclease VII activity
EPJ55_RS06375	COG0142	geranyltranstransferase activity
EPJ55_RS06380	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
EPJ55_RS06385	COG1438	arginine binding
EPJ55_RS06390	COG0497	DNA recombination
EPJ55_RS06405	COG1732	Glycine betaine
EPJ55_RS06420	COG0194	GDP metabolic process
EPJ55_RS06425	COG1758	RNA polymerase activity
EPJ55_RS06430	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
EPJ55_RS06435	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
EPJ55_RS06440	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
EPJ55_RS06445	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EPJ55_RS06445	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
EPJ55_RS06450	COG0631	protein serine/threonine phosphatase activity
EPJ55_RS06455	COG0515	serine threonine protein kinase
EPJ55_RS06455	COG2815	serine threonine protein kinase
EPJ55_RS06460	COG1162	GTPase activity
EPJ55_RS06465	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
EPJ55_RS06470	COG1564	THIamine pyrophosphokinase
EPJ55_RS06480	COG0227	Belongs to the bacterial ribosomal protein bL28 family
EPJ55_RS06485	COG1302	Protein conserved in bacteria
EPJ55_RS06490	COG1461	Dihydroxyacetone kinase
EPJ55_RS06495	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
EPJ55_RS06500	COG0416	fatty acid biosynthetic process
EPJ55_RS06505	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EPJ55_RS06510	COG0571	ribonuclease III activity
EPJ55_RS06515	COG1196	nuclear chromosome segregation
EPJ55_RS06520	COG0552	protein localization to endoplasmic reticulum
EPJ55_RS06525	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
EPJ55_RS06530	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
EPJ55_RS06535	COG0228	four-way junction DNA binding
EPJ55_RS06540	COG1837	Belongs to the UPF0109 family
EPJ55_RS06545	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
EPJ55_RS06550	COG0336	Belongs to the RNA methyltransferase TrmD family
EPJ55_RS06555	COG0335	large ribosomal subunit rRNA binding
EPJ55_RS06590	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
EPJ55_RS06590	COG0512	Glutamine amidotransferase of anthranilate synthase
EPJ55_RS06595	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
EPJ55_RS06600	COG0134	indole-3-glycerol-phosphate synthase activity
EPJ55_RS06605	COG0135	phosphoribosylanthranilate isomerase activity
EPJ55_RS06610	COG0133	tryptophan synthase activity
EPJ55_RS06615	COG0159	tryptophan synthase activity
EPJ55_RS06630	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EPJ55_RS06640	COG1473	amidohydrolase
EPJ55_RS06645	COG1063	alcohol dehydrogenase
EPJ55_RS06655	COG0300	oxidoreductase activity
EPJ55_RS06665	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
EPJ55_RS06670	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EPJ55_RS06675	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EPJ55_RS06680	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
EPJ55_RS06685	COG1028	Short-chain dehydrogenase reductase Sdr
EPJ55_RS06690	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
EPJ55_RS06705	COG0439	Biotin carboxylase
EPJ55_RS06720	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
EPJ55_RS06730	COG1811	Na channel or pump
EPJ55_RS06735	COG0583	DNA-binding transcription factor activity
EPJ55_RS06740	COG1607	acyl-coa hydrolase
EPJ55_RS06745	COG1162	GTPase activity
EPJ55_RS06755	COG0477	Major facilitator Superfamily
EPJ55_RS06775	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
EPJ55_RS06780	COG3397	chitin binding
EPJ55_RS06785	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
EPJ55_RS06795	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
EPJ55_RS06805	COG3152	Membrane
EPJ55_RS06810	COG1597	lipid kinase activity
EPJ55_RS06820	COG2261	transglycosylase associated protein
EPJ55_RS06825	COG3237	CsbD-like
EPJ55_RS06840	COG1942	4-Oxalocrotonate Tautomerase
EPJ55_RS06875	COG0531	amino acid
EPJ55_RS06880	COG0561	phosphatase activity
EPJ55_RS06885	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
EPJ55_RS06885	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
EPJ55_RS06905	COG2017	converts alpha-aldose to the beta-anomer
EPJ55_RS06910	COG1304	FMN binding
EPJ55_RS06930	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
EPJ55_RS06930	COG1199	ATP-dependent helicase activity
EPJ55_RS06945	COG0017	Asparaginyl-tRNA synthetase
EPJ55_RS06960	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
EPJ55_RS06965	COG2011	ABC-type metal ion transport system permease component
EPJ55_RS06970	COG1464	Belongs to the NlpA lipoprotein family
EPJ55_RS06985	COG1840	ABC-type Fe3 transport system, periplasmic component
EPJ55_RS07000	COG3331	DNA recombination
EPJ55_RS07005	COG4474	Belongs to the UPF0398 family
EPJ55_RS07010	COG3599	regulation of cell shape
EPJ55_RS07020	COG0116	Belongs to the methyltransferase superfamily
EPJ55_RS07025	COG1073	alpha beta
EPJ55_RS07035	COG1216	Glycosyl transferase, family 2
EPJ55_RS07055	COG1619	proteins homologs of microcin C7 resistance protein MccF
EPJ55_RS07085	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EPJ55_RS07100	COG2759	Belongs to the formate--tetrahydrofolate ligase family
EPJ55_RS07105	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
EPJ55_RS07110	COG0564	pseudouridine synthase activity
EPJ55_RS07115	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
EPJ55_RS07120	COG0505	Belongs to the CarA family
EPJ55_RS07125	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
EPJ55_RS07135	COG5646	InterPro IPR014922
EPJ55_RS07160	COG1131	(ABC) transporter
EPJ55_RS07165	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
EPJ55_RS07170	COG1293	RNA-binding protein homologous to eukaryotic snRNP
EPJ55_RS07180	COG1307	EDD domain protein, DegV family
EPJ55_RS07235	COG1113	amino acid transport
EPJ55_RS07250	COG1620	l-lactate permease
EPJ55_RS07260	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
EPJ55_RS07270	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
EPJ55_RS07285	COG1846	Transcriptional regulator
EPJ55_RS07325	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EPJ55_RS07330	COG1227	inorganic diphosphatase activity
EPJ55_RS07335	COG0583	DNA-binding transcription factor activity
EPJ55_RS07345	COG0187	DNA topoisomerase II activity
EPJ55_RS07350	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
EPJ55_RS07360	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
EPJ55_RS07365	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
EPJ55_RS07370	COG4974	Belongs to the 'phage' integrase family
EPJ55_RS07375	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
EPJ55_RS07380	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EPJ55_RS07385	COG0758	DNA mediated transformation
EPJ55_RS07390	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
EPJ55_RS07395	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
EPJ55_RS07400	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
EPJ55_RS07405	COG0583	DNA-binding transcription factor activity
EPJ55_RS07425	COG2814	Major facilitator Superfamily
EPJ55_RS07430	COG3409	Peptidoglycan-binding domain 1 protein
EPJ55_RS07430	COG0793	Belongs to the peptidase S41A family
EPJ55_RS07435	COG4479	Belongs to the UPF0346 family
EPJ55_RS07440	COG4698	Protein conserved in bacteria
EPJ55_RS07445	COG2755	lipolytic protein G-D-S-L family
EPJ55_RS07450	COG1307	EDD domain protein, DegV family
EPJ55_RS07455	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
EPJ55_RS07460	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
EPJ55_RS07465	COG0488	(ABC) transporter
EPJ55_RS07475	COG0617	tRNA 3'-terminal CCA addition
EPJ55_RS07480	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
EPJ55_RS07485	COG0561	phosphatase activity
EPJ55_RS07490	COG0457	Tetratricopeptide repeat
EPJ55_RS07500	COG1160	GTP binding
EPJ55_RS07505	COG0539	negative regulation of cytoplasmic translation
EPJ55_RS07520	COG0514	ATP-dependent DNA helicase (RecQ)
EPJ55_RS07530	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
EPJ55_RS07535	COG1187	pseudouridine synthase activity
EPJ55_RS07540	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
EPJ55_RS07545	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
EPJ55_RS07555	COG4974	Belongs to the 'phage' integrase family
EPJ55_RS07560	COG2996	Protein conserved in bacteria
EPJ55_RS07575	COG0205	6-phosphofructokinase activity
EPJ55_RS07580	COG0587	DNA-directed DNA polymerase activity
EPJ55_RS07595	COG0542	response to heat
EPJ55_RS07605	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
EPJ55_RS07610	COG2384	SAM-dependent methyltransferase
EPJ55_RS07635	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
EPJ55_RS07635	COG0574	Belongs to the PEP-utilizing enzyme family
EPJ55_RS07645	COG1846	Transcriptional regulator
EPJ55_RS07665	COG2217	Heavy metal translocating P-type atpase
EPJ55_RS07670	COG0148	phosphopyruvate hydratase activity
EPJ55_RS07685	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EPJ55_RS07695	COG1349	DNA-binding transcription factor activity
EPJ55_RS07705	COG1393	Belongs to the ArsC family
EPJ55_RS07750	COG0546	phosphoglycolate phosphatase activity
EPJ55_RS07780	COG0583	DNA-binding transcription factor activity
EPJ55_RS07785	COG0604	alcohol dehydrogenase
EPJ55_RS07795	COG0446	pyridine nucleotide-disulphide oxidoreductase
EPJ55_RS07800	COG2197	response regulator
EPJ55_RS07805	COG4585	Histidine kinase
EPJ55_RS07815	COG1131	(ABC) transporter
EPJ55_RS07825	COG0519	Catalyzes the synthesis of GMP from XMP
EPJ55_RS07855	COG1131	(ABC) transporter
EPJ55_RS07875	COG1131	(ABC) transporter
EPJ55_RS07880	COG1725	Transcriptional regulator
EPJ55_RS07885	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EPJ55_RS07890	COG0358	DNA primase activity
EPJ55_RS07895	COG0751	glycine-tRNA ligase activity
EPJ55_RS07900	COG0752	glycyl-tRNA synthetase alpha subunit
EPJ55_RS07905	COG1381	Involved in DNA repair and RecF pathway recombination
EPJ55_RS07910	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
EPJ55_RS07915	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
EPJ55_RS07920	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
EPJ55_RS07925	COG1702	phosphate starvation-inducible protein PhoH
EPJ55_RS07930	COG1610	YqeY-like protein
EPJ55_RS07935	COG0828	Belongs to the bacterial ribosomal protein bS21 family
EPJ55_RS07940	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
EPJ55_RS07950	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
EPJ55_RS07960	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EPJ55_RS07970	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
EPJ55_RS07975	COG0124	histidyl-tRNA synthetase
EPJ55_RS07980	COG4991	sh3 domain protein
EPJ55_RS07980	COG0860	N-Acetylmuramoyl-L-alanine amidase
EPJ55_RS07980	COG3103	Sh3 type 3 domain protein
EPJ55_RS07985	COG3001	Fructosamine kinase
EPJ55_RS07990	COG0546	phosphoglycolate phosphatase activity
EPJ55_RS07995	COG1490	D-aminoacyl-tRNA deacylase activity
EPJ55_RS08000	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EPJ55_RS08010	COG1385	rRNA (uridine-N3-)-methyltransferase activity
EPJ55_RS08015	COG2264	protein methyltransferase activity
EPJ55_RS08020	COG2094	Belongs to the DNA glycosylase MPG family
EPJ55_RS08045	COG0481	GTPase activity
EPJ55_RS08050	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
EPJ55_RS08055	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EPJ55_RS08060	COG1696	Membrane protein involved in D-alanine export
EPJ55_RS08065	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EPJ55_RS08075	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EPJ55_RS08080	COG0484	heat shock protein binding
EPJ55_RS08085	COG0443	Heat shock 70 kDa protein
EPJ55_RS08090	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
EPJ55_RS08095	COG1420	regulation of RNA biosynthetic process
EPJ55_RS08100	COG3527	Alpha-acetolactate decarboxylase
EPJ55_RS08105	COG0196	riboflavin kinase activity
EPJ55_RS08110	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
EPJ55_RS08115	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
EPJ55_RS08120	COG0287	Prephenate dehydrogenase
EPJ55_RS08125	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
EPJ55_RS08135	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
EPJ55_RS08140	COG0738	Major facilitator superfamily
EPJ55_RS08145	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
EPJ55_RS08150	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
EPJ55_RS08160	COG2740	Nucleic-acid-binding protein implicated in transcription termination
EPJ55_RS08165	COG0195	Participates in both transcription termination and antitermination
EPJ55_RS08170	COG0779	Required for maturation of 30S ribosomal subunits
EPJ55_RS08175	COG2176	DNA-directed DNA polymerase activity
EPJ55_RS08180	COG0442	prolyl-tRNA aminoacylation
EPJ55_RS08185	COG0750	zinc metalloprotease
EPJ55_RS08190	COG4589	Belongs to the CDS family
EPJ55_RS08195	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
EPJ55_RS08200	COG0233	cytoplasmic translational termination
EPJ55_RS08205	COG0528	UMP kinase activity
EPJ55_RS08210	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
EPJ55_RS08215	COG0052	Belongs to the universal ribosomal protein uS2 family
EPJ55_RS08225	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EPJ55_RS08230	COG2827	Endonuclease containing a URI domain
EPJ55_RS08235	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
EPJ55_RS08240	COG0204	Acyl-transferase
EPJ55_RS08245	COG3763	UPF0154 protein
EPJ55_RS08250	COG4224	UPF0291 protein
EPJ55_RS08255	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
EPJ55_RS08270	COG3425	synthase
EPJ55_RS08285	COG0463	Glycosyl transferase, family 2
EPJ55_RS08295	COG1316	TRANSCRIPTIONal
EPJ55_RS08300	COG1116	anion transmembrane transporter activity
EPJ55_RS08310	COG0772	Belongs to the SEDS family
EPJ55_RS08370	COG3953	SLT domain
EPJ55_RS08370	COG5280	Phage tail tape measure protein TP901
EPJ55_RS08580	COG1396	sequence-specific DNA binding
EPJ55_RS08590	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
EPJ55_RS08625	COG0393	Putative heavy-metal-binding
EPJ55_RS08640	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
EPJ55_RS08645	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
EPJ55_RS08645	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
EPJ55_RS08650	COG5416	Lipopolysaccharide assembly protein A domain
EPJ55_RS08655	COG0300	oxidoreductase activity
EPJ55_RS08660	COG1234	tRNA 3'-trailer cleavage
EPJ55_RS08670	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
EPJ55_RS08680	COG1105	Belongs to the carbohydrate kinase PfkB family
EPJ55_RS08685	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EPJ55_RS08685	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EPJ55_RS08685	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EPJ55_RS08690	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
EPJ55_RS08715	COG0297	glycogen (starch) synthase activity
EPJ55_RS08720	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
EPJ55_RS08725	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EPJ55_RS08735	COG0489	protein tyrosine kinase activity
EPJ55_RS08745	COG0322	excinuclease ABC activity
EPJ55_RS08750	COG1126	abc transporter atp-binding protein
EPJ55_RS08755	COG0765	amino acid transport
EPJ55_RS08775	COG0218	Necessary for normal cell division and for the maintenance of normal septation
EPJ55_RS08780	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
EPJ55_RS08785	COG0544	peptidyl-prolyl cis-trans isomerase activity
EPJ55_RS08790	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
EPJ55_RS08815	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
EPJ55_RS08820	COG0268	Binds directly to 16S ribosomal RNA
EPJ55_RS08825	COG1466	dna polymerase III delta subunit
EPJ55_RS08830	COG0658	competence protein
EPJ55_RS08830	COG2333	competence protein COMEC
EPJ55_RS08835	COG2131	deaminase
EPJ55_RS08840	COG1555	photosystem II stabilization
EPJ55_RS08840	COG1596	polysaccharide export
EPJ55_RS08845	COG3480	Lon protease (S16) C-terminal proteolytic domain
EPJ55_RS08850	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
EPJ55_RS08855	COG0742	ribosomal rna small subunit methyltransferase
EPJ55_RS08860	COG4471	UPF0298 protein
EPJ55_RS08865	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
EPJ55_RS08870	COG0772	Belongs to the SEDS family
EPJ55_RS08895	COG1217	gtp-binding protein TYPA
EPJ55_RS08900	COG0483	inositol monophosphate 1-phosphatase activity
EPJ55_RS08905	COG4476	Belongs to the UPF0223 family
EPJ55_RS08910	COG0039	L-malate dehydrogenase activity
EPJ55_RS08935	COG0242	peptide deformylase activity
EPJ55_RS08945	COG5503	Protein of unknown function (DUF1447)
EPJ55_RS08950	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
EPJ55_RS08955	COG1597	lipid kinase activity
EPJ55_RS08965	COG1388	LysM domain
EPJ55_RS08965	COG3584	3D domain protein
EPJ55_RS08975	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
EPJ55_RS08980	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
EPJ55_RS09010	COG0569	domain protein
EPJ55_RS09015	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
EPJ55_RS09020	COG0482	sulfurtransferase activity
EPJ55_RS09030	COG1104	cysteine desulfurase activity
EPJ55_RS09035	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
EPJ55_RS09045	COG0494	nUDIX hydrolase
EPJ55_RS09050	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
EPJ55_RS09055	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
EPJ55_RS09060	COG3599	regulation of cell shape
EPJ55_RS09070	COG0762	integral membrane protein
EPJ55_RS09075	COG1799	cell septum assembly
EPJ55_RS09090	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
EPJ55_RS09095	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
EPJ55_RS09100	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
EPJ55_RS09105	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EPJ55_RS09110	COG0768	penicillin binding
EPJ55_RS09120	COG0275	rRNA processing
EPJ55_RS09125	COG2001	Belongs to the MraZ family
EPJ55_RS09145	COG1674	ftsk spoiiie
EPJ55_RS09150	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
EPJ55_RS09160	COG1114	Component of the transport system for branched-chain amino acids
EPJ55_RS09170	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
EPJ55_RS09175	COG0628	permease
EPJ55_RS09185	COG2706	6-phosphogluconolactonase activity
EPJ55_RS09190	COG3142	Participates in the control of copper homeostasis
EPJ55_RS09195	COG0564	pseudouridine synthase activity
EPJ55_RS09200	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
EPJ55_RS09205	COG2357	RelA SpoT domain protein
EPJ55_RS09215	COG1164	Oligoendopeptidase f
EPJ55_RS09225	COG4862	establishment of competence for transformation
EPJ55_RS09230	COG1393	Belongs to the ArsC family
EPJ55_RS09235	COG1234	tRNA 3'-trailer cleavage
EPJ55_RS09360	COG1098	S1 RNA binding domain
EPJ55_RS09370	COG0586	Pfam SNARE associated Golgi protein
EPJ55_RS09380	COG0647	UMP catabolic process
EPJ55_RS09385	COG4470	Protein conserved in bacteria
EPJ55_RS09390	COG0737	Belongs to the 5'-nucleotidase family
EPJ55_RS09400	COG1113	amino acid transport
EPJ55_RS09405	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
EPJ55_RS09410	COG0827	DNA restriction-modification system
EPJ55_RS09440	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
EPJ55_RS09450	COG0217	transcriptional regulatory protein
EPJ55_RS09465	COG1609	Transcriptional regulator
EPJ55_RS09470	COG0006	proline dipeptidase activity
EPJ55_RS09475	COG0789	Transcriptional regulator
EPJ55_RS09490	COG0668	transmembrane transport
EPJ55_RS09495	COG1473	amidohydrolase
EPJ55_RS09500	COG2171	N-acyltransferase activity
EPJ55_RS09505	COG0517	IMP dehydrogenase activity
EPJ55_RS09515	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
EPJ55_RS09520	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
EPJ55_RS09525	COG1719	4-vinyl reductase, 4VR
EPJ55_RS09530	COG3118	belongs to the thioredoxin family
EPJ55_RS09535	COG1193	negative regulation of DNA recombination
EPJ55_RS09545	COG3906	Belongs to the UPF0473 family
EPJ55_RS09550	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
EPJ55_RS09555	COG4472	Bacterial protein of unknown function (DUF965)
EPJ55_RS09560	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
EPJ55_RS09565	COG0513	Belongs to the DEAD box helicase family
EPJ55_RS09570	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
EPJ55_RS09575	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EPJ55_RS09580	COG1862	Preprotein translocase
EPJ55_RS09585	COG0343	queuine tRNA-ribosyltransferase activity
EPJ55_RS09590	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
EPJ55_RS09595	COG2255	four-way junction helicase activity
EPJ55_RS09600	COG0632	four-way junction helicase activity
EPJ55_RS09620	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
EPJ55_RS09625	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
EPJ55_RS09630	COG1692	metallophosphoesterase
EPJ55_RS09635	COG1418	mRNA catabolic process
EPJ55_RS09640	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
EPJ55_RS09645	COG1546	Belongs to the CinA family
EPJ55_RS09645	COG1058	Belongs to the CinA family
EPJ55_RS09650	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
EPJ55_RS09655	COG1426	Protein conserved in bacteria
EPJ55_RS09660	COG0612	Peptidase, M16
EPJ55_RS09665	COG0612	Peptidase, M16
EPJ55_RS09670	COG0527	aspartate kinase activity
EPJ55_RS09675	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EPJ55_RS09680	COG1126	abc transporter atp-binding protein
EPJ55_RS09685	COG0765	amino acid transport
EPJ55_RS09690	COG2894	cell division
EPJ55_RS09695	COG0850	regulation of cytokinetic process
EPJ55_RS09705	COG1792	Involved in formation and maintenance of cell shape
EPJ55_RS09710	COG1077	Cell shape determining protein MreB Mrl
EPJ55_RS09715	COG2003	Belongs to the UPF0758 family
EPJ55_RS09720	COG0285	dihydrofolate synthase activity
EPJ55_RS09725	COG0525	valine-tRNA ligase activity
EPJ55_RS09735	COG1181	Belongs to the D-alanine--D-alanine ligase family
EPJ55_RS09735	COG2918	glutathione biosynthetic process
EPJ55_RS09740	COG0301	tRNA thio-modification
EPJ55_RS09745	COG1104	cysteine desulfurase activity
EPJ55_RS09750	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
EPJ55_RS09755	COG1956	GAF domain-containing protein
EPJ55_RS09760	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
EPJ55_RS09765	COG4493	Belongs to the UPF0637 family
EPJ55_RS09780	COG0640	Transcriptional regulator
EPJ55_RS09785	COG0189	ligase activity
EPJ55_RS09785	COG2918	glutathione biosynthetic process
EPJ55_RS09790	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
EPJ55_RS09805	COG0589	response to stress
EPJ55_RS09825	COG1181	Belongs to the D-alanine--D-alanine ligase family
EPJ55_RS09845	COG1464	Belongs to the NlpA lipoprotein family
EPJ55_RS09855	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
EPJ55_RS09860	COG0509	glycine decarboxylation via glycine cleavage system
EPJ55_RS09865	COG0772	Belongs to the SEDS family
EPJ55_RS09875	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
EPJ55_RS09890	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
EPJ55_RS09895	COG0355	proton-transporting ATP synthase activity, rotational mechanism
EPJ55_RS09900	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
EPJ55_RS09905	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
EPJ55_RS09910	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
EPJ55_RS09915	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
EPJ55_RS09920	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
EPJ55_RS09925	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
EPJ55_RS09930	COG0356	it plays a direct role in the translocation of protons across the membrane
EPJ55_RS09935	COG2233	PERMEase
EPJ55_RS09945	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
EPJ55_RS09950	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
EPJ55_RS09955	COG0009	L-threonylcarbamoyladenylate synthase
EPJ55_RS09960	COG2890	protein-(glutamine-N5) methyltransferase activity
EPJ55_RS09965	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
EPJ55_RS09970	COG1435	thymidine kinase activity
EPJ55_RS09975	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
EPJ55_RS09980	COG3442	glutamine amidotransferase
EPJ55_RS09985	COG1482	cell wall glycoprotein biosynthetic process
EPJ55_RS09990	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EPJ55_RS10000	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EPJ55_RS10015	COG1132	(ABC) transporter
EPJ55_RS10030	COG0726	polysaccharide deacetylase
EPJ55_RS10295	COG1396	sequence-specific DNA binding
EPJ55_RS10395	COG4695	Portal protein
EPJ55_RS10460	COG4974	Belongs to the 'phage' integrase family
EPJ55_RS10485	COG4932	domain protein
EPJ55_RS10485	COG4886	Leucine-rich repeat (LRR) protein
EPJ55_RS10495	COG1132	(ABC) transporter
EPJ55_RS10570	COG4932	domain protein
EPJ55_RS10570	COG5492	domain, Protein
EPJ55_RS10620	COG3728	DNA packaging
EPJ55_RS10620	COG5484	DNA packaging
EPJ55_RS10675	COG0270	DNA (cytosine-5-)-methyltransferase activity
EPJ55_RS10740	COG1396	sequence-specific DNA binding
EPJ55_RS10785	COG4975	Glucose uptake
EPJ55_RS10790	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
EPJ55_RS10795	COG5002	protein histidine kinase activity
EPJ55_RS10795	COG3850	Histidine kinase
EPJ55_RS10800	COG0745	RESPONSE REGULATOR receiver
EPJ55_RS10805	COG2848	UPF0210 protein
EPJ55_RS10810	COG3830	Belongs to the UPF0237 family
EPJ55_RS10840	COG0477	Major facilitator Superfamily
EPJ55_RS10860	COG0791	NLP P60 protein
EPJ55_RS10865	COG1522	sequence-specific DNA binding
EPJ55_RS10890	COG0488	(ABC) transporter
EPJ55_RS10915	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
EPJ55_RS10920	COG1307	EDD domain protein, DegV family
EPJ55_RS10930	COG2873	o-acetylhomoserine
EPJ55_RS10935	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
EPJ55_RS10945	COG4120	Belongs to the binding-protein-dependent transport system permease family
EPJ55_RS10955	COG0446	pyridine nucleotide-disulphide oxidoreductase
EPJ55_RS10960	COG2084	Dehydrogenase
EPJ55_RS10965	COG0861	Integral membrane protein TerC family
EPJ55_RS10970	COG0110	maltose O-acetyltransferase activity
EPJ55_RS10975	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
EPJ55_RS10980	COG0140	phosphoribosyl-ATP diphosphatase activity
EPJ55_RS10985	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
EPJ55_RS10990	COG0107	imidazoleglycerol-phosphate synthase activity
EPJ55_RS10995	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
EPJ55_RS11000	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
EPJ55_RS11005	COG0131	Imidazoleglycerol-phosphate dehydratase
EPJ55_RS11010	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
EPJ55_RS11015	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
EPJ55_RS11020	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
EPJ55_RS11025	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
EPJ55_RS11065	COG3548	integral membrane protein
EPJ55_RS11075	COG4372	Transposase
EPJ55_RS11105	COG1368	sulfuric ester hydrolase activity
EPJ55_RS11110	COG0584	glycerophosphoryl diester phosphodiesterase
EPJ55_RS11115	COG0492	ferredoxin-NADP+ reductase activity
EPJ55_RS11125	COG4932	domain protein
EPJ55_RS11130	COG2326	polyphosphate kinase activity
EPJ55_RS11135	COG0778	Nitroreductase
EPJ55_RS11145	COG0328	RNA-DNA hybrid ribonuclease activity
EPJ55_RS11155	COG1609	Transcriptional regulator
EPJ55_RS11165	COG0673	inositol 2-dehydrogenase activity
EPJ55_RS11170	COG0673	inositol 2-dehydrogenase activity
EPJ55_RS11175	COG0025	NhaP-type Na H and K H
EPJ55_RS11185	COG1335	isochorismatase
EPJ55_RS11195	COG1131	(ABC) transporter
EPJ55_RS11200	COG1725	Transcriptional regulator
EPJ55_RS11240	COG0028	Belongs to the TPP enzyme family
EPJ55_RS11250	COG1073	alpha beta
EPJ55_RS11255	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EPJ55_RS11260	COG0626	cystathionine gamma-synthase activity
EPJ55_RS11290	COG0095	Lipoate-protein ligase
EPJ55_RS11295	COG1705	Flagellar rod assembly protein muramidase FlgJ
EPJ55_RS11305	COG0589	response to stress
EPJ55_RS11310	COG0564	pseudouridine synthase activity
EPJ55_RS11325	COG4640	response to antibiotic
EPJ55_RS11330	COG1396	sequence-specific DNA binding
EPJ55_RS11345	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
EPJ55_RS11355	COG2188	Transcriptional regulator
EPJ55_RS11360	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
EPJ55_RS11370	COG1418	mRNA catabolic process
EPJ55_RS11400	COG1253	flavin adenine dinucleotide binding
EPJ55_RS11405	COG1780	Probably involved in ribonucleotide reductase function
EPJ55_RS11410	COG0025	NhaP-type Na H and K H
EPJ55_RS11415	COG2814	Major facilitator Superfamily
EPJ55_RS11420	COG0789	Transcriptional regulator
EPJ55_RS11425	COG0604	alcohol dehydrogenase
EPJ55_RS11435	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
EPJ55_RS11440	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EPJ55_RS11445	COG0436	Aminotransferase
EPJ55_RS11450	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EPJ55_RS11460	COG0583	DNA-binding transcription factor activity
EPJ55_RS11465	COG0702	epimerase
EPJ55_RS11475	COG1074	ATP-dependent DNA helicase activity
EPJ55_RS11480	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
EPJ55_RS11490	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
EPJ55_RS11495	COG0284	orotidine-5'-phosphate decarboxylase activity
EPJ55_RS11500	COG0167	dihydroorotate dehydrogenase activity
EPJ55_RS11505	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
EPJ55_RS11510	COG0505	Belongs to the CarA family
EPJ55_RS11515	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
EPJ55_RS11520	COG0540	Belongs to the ATCase OTCase family
EPJ55_RS11525	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
EPJ55_RS11530	COG2508	Transcriptional regulator
EPJ55_RS11535	COG2233	PERMEase
EPJ55_RS11540	COG2252	PERMEase
EPJ55_RS11570	COG0151	Belongs to the GarS family
EPJ55_RS11575	COG0138	bifunctional purine biosynthesis protein purh
EPJ55_RS11580	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
EPJ55_RS11585	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
EPJ55_RS11595	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EPJ55_RS11600	COG0047	phosphoribosylformylglycinamidine synthase activity
EPJ55_RS11605	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EPJ55_RS11610	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
EPJ55_RS11615	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
EPJ55_RS11625	COG3976	FMN-binding domain protein
EPJ55_RS11625	COG1053	succinate dehydrogenase
EPJ55_RS11625	COG0431	NADPH-dependent FMN reductase
EPJ55_RS11630	COG1053	succinate dehydrogenase
EPJ55_RS11630	COG0431	NADPH-dependent FMN reductase
EPJ55_RS11630	COG3976	FMN-binding domain protein
EPJ55_RS11635	COG0095	Lipoate-protein ligase
EPJ55_RS11640	COG2365	Tyrosine phosphatase family
EPJ55_RS11660	COG1136	(ABC) transporter
EPJ55_RS11675	COG1725	Transcriptional regulator
EPJ55_RS11680	COG1131	(ABC) transporter
EPJ55_RS11690	COG0589	response to stress
EPJ55_RS11700	COG2246	polysaccharide biosynthetic process
EPJ55_RS11720	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
EPJ55_RS11740	COG0366	Alpha amylase catalytic
EPJ55_RS11750	COG0561	phosphatase activity
EPJ55_RS11760	COG0110	maltose O-acetyltransferase activity
EPJ55_RS11765	COG0494	nUDIX hydrolase
EPJ55_RS11795	COG1827	regulation of RNA biosynthetic process
EPJ55_RS11800	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
EPJ55_RS11805	COG1309	transcriptional regulator
EPJ55_RS11815	COG1131	(ABC) transporter
EPJ55_RS11820	COG3048	D-serine ammonia-lyase activity
EPJ55_RS11825	COG2723	6-phospho-beta-galactosidase activity
EPJ55_RS11830	COG2723	6-phospho-beta-galactosidase activity
EPJ55_RS11835	COG1447	Phosphotransferase system cellobiose-specific component IIA
EPJ55_RS11840	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EPJ55_RS11850	COG1216	Glycosyl transferase, family 2
EPJ55_RS11865	COG0561	phosphatase activity
EPJ55_RS11870	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
EPJ55_RS11895	COG0716	FMN binding
EPJ55_RS11915	COG0710	3-dehydroquinate dehydratase activity
EPJ55_RS11965	COG4720	Psort location CytoplasmicMembrane, score
EPJ55_RS11970	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
EPJ55_RS11985	COG4990	cell redox homeostasis
EPJ55_RS11995	COG1811	Na channel or pump
EPJ55_RS12000	COG0789	Transcriptional regulator
EPJ55_RS12000	COG4978	Transcriptional regulator
EPJ55_RS12015	COG0577	efflux transmembrane transporter activity
EPJ55_RS12020	COG1136	(ABC) transporter
EPJ55_RS12065	COG2814	Major facilitator Superfamily
EPJ55_RS12075	COG2814	Major facilitator Superfamily
EPJ55_RS12085	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EPJ55_RS12090	COG2855	membrane
EPJ55_RS12095	COG0583	DNA-binding transcription factor activity
EPJ55_RS12105	COG0438	transferase activity, transferring glycosyl groups
EPJ55_RS12120	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EPJ55_RS12125	COG4152	abc transporter atp-binding protein
EPJ55_RS12135	COG4221	oxidoreductase activity
EPJ55_RS12150	COG0789	Transcriptional regulator
EPJ55_RS12175	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
EPJ55_RS12200	COG0456	acetyltransferase
EPJ55_RS12225	COG0583	DNA-binding transcription factor activity
EPJ55_RS12235	COG1063	alcohol dehydrogenase
EPJ55_RS12240	COG1028	Short-chain dehydrogenase reductase Sdr
EPJ55_RS12250	COG0589	response to stress
EPJ55_RS12255	COG0110	maltose O-acetyltransferase activity
EPJ55_RS12260	COG1011	Hydrolase
EPJ55_RS12270	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
EPJ55_RS12280	COG0667	Aldo Keto reductase
EPJ55_RS12285	COG1132	(ABC) transporter
EPJ55_RS12290	COG1132	(ABC) transporter
EPJ55_RS12295	COG2814	Major facilitator Superfamily
EPJ55_RS12315	COG1511	domain protein
EPJ55_RS12315	COG1511	domain protein
EPJ55_RS12325	COG0640	Transcriptional regulator
EPJ55_RS12355	COG0561	phosphatase activity
EPJ55_RS12365	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
EPJ55_RS12385	COG2267	carboxylic ester hydrolase activity
EPJ55_RS12390	COG0531	amino acid
EPJ55_RS12395	COG2270	Major facilitator Superfamily
EPJ55_RS12435	COG2200	EAL domain
EPJ55_RS12445	COG1328	CTP reductase activity
EPJ55_RS12455	COG0242	peptide deformylase activity
EPJ55_RS12465	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EPJ55_RS12480	COG0583	DNA-binding transcription factor activity
EPJ55_RS12490	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
EPJ55_RS12535	COG0697	spore germination
EPJ55_RS12560	COG1940	carbohydrate kinase activity
EPJ55_RS12565	COG1132	(ABC) transporter
EPJ55_RS12575	COG0778	Nitroreductase
EPJ55_RS12585	COG1116	anion transmembrane transporter activity
EPJ55_RS12590	COG4120	Belongs to the binding-protein-dependent transport system permease family
EPJ55_RS12620	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
EPJ55_RS12620	COG3620	sequence-specific DNA binding
EPJ55_RS12620	COG0617	tRNA 3'-terminal CCA addition
EPJ55_RS12625	COG0410	ABC transporter
EPJ55_RS12640	COG0559	Belongs to the binding-protein-dependent transport system permease family
EPJ55_RS12655	COG5549	protein import
EPJ55_RS12655	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EPJ55_RS12660	COG2246	polysaccharide biosynthetic process
EPJ55_RS12670	COG1914	H( )-stimulated, divalent metal cation uptake system
EPJ55_RS12690	COG0640	Transcriptional regulator
EPJ55_RS12700	COG1136	(ABC) transporter
EPJ55_RS12700	COG0577	efflux transmembrane transporter activity
EPJ55_RS12735	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EPJ55_RS12740	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EPJ55_RS12745	COG2723	6-phospho-beta-galactosidase activity
EPJ55_RS12755	COG0789	Transcriptional regulator
EPJ55_RS12760	COG0741	lytic transglycosylase activity
EPJ55_RS12805	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EPJ55_RS12815	COG1132	(ABC) transporter
EPJ55_RS12820	COG1132	(ABC) transporter
EPJ55_RS12830	COG1473	amidohydrolase
EPJ55_RS12835	COG1028	Short-chain dehydrogenase reductase Sdr
EPJ55_RS12855	COG0531	amino acid
EPJ55_RS12875	COG2217	Heavy metal translocating P-type atpase
EPJ55_RS12930	COG1063	alcohol dehydrogenase
EPJ55_RS12970	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EPJ55_RS12975	COG1733	regulation of RNA biosynthetic process
EPJ55_RS12980	COG2814	Major facilitator Superfamily
EPJ55_RS12990	COG0367	asparagine synthase
EPJ55_RS12995	COG3279	Response regulator of the LytR AlgR family
EPJ55_RS13005	COG1309	transcriptional regulator
EPJ55_RS13015	COG1012	belongs to the aldehyde dehydrogenase family
EPJ55_RS13030	COG1733	regulation of RNA biosynthetic process
EPJ55_RS13035	COG0300	oxidoreductase activity
EPJ55_RS13055	COG4989	oxidoreductase activity
EPJ55_RS13075	COG0477	Major facilitator Superfamily
EPJ55_RS13085	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EPJ55_RS13090	COG1120	ATPase activity
EPJ55_RS13095	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EPJ55_RS13100	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EPJ55_RS13115	COG4221	oxidoreductase activity
EPJ55_RS13120	COG0110	maltose O-acetyltransferase activity
EPJ55_RS13125	COG1028	Short-chain dehydrogenase reductase Sdr
EPJ55_RS13185	COG2816	NAD+ diphosphatase activity
EPJ55_RS13195	COG3976	FMN-binding domain protein
EPJ55_RS13195	COG1053	succinate dehydrogenase
EPJ55_RS13195	COG0431	NADPH-dependent FMN reductase
EPJ55_RS13205	COG0783	Belongs to the Dps family
EPJ55_RS13215	COG2723	6-phospho-beta-galactosidase activity
EPJ55_RS13220	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EPJ55_RS13235	COG0789	Transcriptional regulator
EPJ55_RS13255	COG0693	protein deglycase activity
EPJ55_RS13275	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
EPJ55_RS13290	COG1376	ErfK ybiS ycfS ynhG family protein
EPJ55_RS13300	COG0588	phosphoglycerate mutase activity
EPJ55_RS13305	COG0628	permease
EPJ55_RS13310	COG1846	Transcriptional regulator
EPJ55_RS13310	COG1940	carbohydrate kinase activity
EPJ55_RS13320	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
EPJ55_RS13370	COG1247	-acetyltransferase
EPJ55_RS13375	COG1686	Belongs to the peptidase S11 family
EPJ55_RS13395	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EPJ55_RS13400	COG0517	IMP dehydrogenase activity
EPJ55_RS13400	COG0516	GMP reductase activity
EPJ55_RS13410	COG0012	GTP binding
EPJ55_RS13415	COG4481	Protein conserved in bacteria
EPJ55_RS13420	COG1475	DNA binding
EPJ55_RS13425	COG1192	Involved in chromosome partitioning
EPJ55_RS13435	COG0357	Ribosomal RNA small subunit methyltransferase G
EPJ55_RS13440	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EPJ55_RS13450	COG0583	DNA-binding transcription factor activity
EPJ55_RS13455	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EPJ55_RS13460	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EPJ55_RS13465	COG0765	amino acid transport
EPJ55_RS13470	COG1126	abc transporter atp-binding protein
EPJ55_RS13500	COG2190	(PTS) system
EPJ55_RS13500	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EPJ55_RS13500	COG1263	PTS System
EPJ55_RS13505	COG0366	Alpha amylase catalytic
EPJ55_RS13510	COG1609	Transcriptional regulator
EPJ55_RS13520	COG0390	transport system, permease component
EPJ55_RS13525	COG4619	ABC transporter
EPJ55_RS13530	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
EPJ55_RS13545	COG0561	phosphatase activity
EPJ55_RS13560	COG1263	PTS System
EPJ55_RS13560	COG2190	(PTS) system
EPJ55_RS13560	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EPJ55_RS13590	COG0735	belongs to the Fur family
EPJ55_RS13615	COG1380	Effector of murein hydrolase LrgA
EPJ55_RS13625	COG1307	EDD domain protein, DegV family
EPJ55_RS13635	COG2738	Putative neutral zinc metallopeptidase
EPJ55_RS13640	COG1233	COG1233 Phytoene dehydrogenase and related
EPJ55_RS13645	COG1562	ergosterol biosynthetic process
EPJ55_RS13655	COG1929	Belongs to the glycerate kinase type-1 family
EPJ55_RS13670	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
EPJ55_RS13675	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
EPJ55_RS13680	COG0516	GMP reductase activity
EPJ55_RS13685	COG2365	Tyrosine phosphatase family
EPJ55_RS13690	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EPJ55_RS13705	COG1511	domain protein
EPJ55_RS13720	COG0531	amino acid
EPJ55_RS13725	COG3158	transport of potassium into the cell
EPJ55_RS13730	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
EPJ55_RS13735	COG0628	permease
EPJ55_RS13740	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
EPJ55_RS13755	COG1272	protein, Hemolysin III
EPJ55_RS13760	COG0640	Transcriptional regulator
EPJ55_RS13785	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
EPJ55_RS13795	COG0302	gtp cyclohydrolase
EPJ55_RS13800	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
EPJ55_RS13815	COG0803	Belongs to the bacterial solute-binding protein 9 family
EPJ55_RS13820	COG2814	Major facilitator Superfamily
EPJ55_RS13850	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EPJ55_RS13855	COG1882	Formate acetyltransferase
EPJ55_RS13860	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
EPJ55_RS13865	COG2151	metal-sulfur cluster biosynthetic enzyme
EPJ55_RS13870	COG4989	oxidoreductase activity
EPJ55_RS13900	COG2217	Heavy metal translocating P-type atpase
EPJ55_RS13910	COG2315	Protein conserved in bacteria
EPJ55_RS13920	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
EPJ55_RS13925	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
EPJ55_RS13935	COG1757	Na H antiporter
EPJ55_RS13940	COG1113	amino acid transport
EPJ55_RS13950	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
EPJ55_RS13965	COG1393	Belongs to the ArsC family
EPJ55_RS13970	COG3189	MarR family transcriptional regulator
EPJ55_RS13980	COG1194	a g-specific adenine glycosylase
EPJ55_RS13995	COG0071	Belongs to the small heat shock protein (HSP20) family
EPJ55_RS14020	COG0697	spore germination
EPJ55_RS14035	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
EPJ55_RS14060	COG0477	Major facilitator Superfamily
EPJ55_RS14115	COG0737	Belongs to the 5'-nucleotidase family
EPJ55_RS14125	COG0656	L-ascorbic acid biosynthetic process
EPJ55_RS14145	COG1968	undecaprenyl-diphosphatase activity
EPJ55_RS14150	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
EPJ55_RS14185	COG2207	Transcriptional regulator
EPJ55_RS14210	COG0076	glutamate decarboxylase activity
EPJ55_RS14245	COG2226	methyltransferase
EPJ55_RS14260	COG2217	Heavy metal translocating P-type atpase
EPJ55_RS14265	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
EPJ55_RS14270	COG3118	belongs to the thioredoxin family
EPJ55_RS14275	COG1937	Protein conserved in bacteria
EPJ55_RS14300	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EPJ55_RS14305	COG3590	peptidase
EPJ55_RS14315	COG0446	pyridine nucleotide-disulphide oxidoreductase
EPJ55_RS14365	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
EPJ55_RS14375	COG1114	Component of the transport system for branched-chain amino acids
EPJ55_RS14385	COG1874	Beta-galactosidase
EPJ55_RS14390	COG1609	Transcriptional regulator
EPJ55_RS14410	COG0477	Major facilitator Superfamily
EPJ55_RS14430	COG2184	nucleotidyltransferase activity
EPJ55_RS14435	COG2944	sequence-specific DNA binding
EPJ55_RS14440	COG1609	Transcriptional regulator
EPJ55_RS14445	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
EPJ55_RS14450	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
EPJ55_RS14455	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
EPJ55_RS14475	COG2190	(PTS) system
EPJ55_RS14475	COG2211	Major facilitator Superfamily
EPJ55_RS14480	COG2017	converts alpha-aldose to the beta-anomer
EPJ55_RS14485	COG1609	Transcriptional regulator
EPJ55_RS14490	COG0667	Aldo Keto reductase
EPJ55_RS14510	COG0710	3-dehydroquinate dehydratase activity
EPJ55_RS14515	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
EPJ55_RS14520	COG0583	DNA-binding transcription factor activity
EPJ55_RS14525	COG2271	Major facilitator Superfamily
EPJ55_RS14540	COG1028	Short-chain dehydrogenase reductase Sdr
EPJ55_RS14555	COG2271	Major facilitator Superfamily
EPJ55_RS14565	COG2267	carboxylic ester hydrolase activity
EPJ55_RS14570	COG2188	Transcriptional regulator
EPJ55_RS14575	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EPJ55_RS14580	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
EPJ55_RS14585	COG2971	BadF BadG BcrA BcrD
EPJ55_RS14595	COG2723	6-phospho-beta-galactosidase activity
EPJ55_RS14605	COG3711	transcriptional antiterminator
EPJ55_RS14615	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
EPJ55_RS14620	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EPJ55_RS14620	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EPJ55_RS14625	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EPJ55_RS14625	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EPJ55_RS14625	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EPJ55_RS14630	COG2190	(PTS) system
EPJ55_RS14630	COG1263	PTS System
EPJ55_RS14630	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EPJ55_RS14635	COG1737	Transcriptional regulator
EPJ55_RS14640	COG1263	PTS System
EPJ55_RS14640	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EPJ55_RS14645	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
EPJ55_RS14655	COG2723	6-phospho-beta-galactosidase activity
EPJ55_RS14660	COG2723	6-phospho-beta-galactosidase activity
EPJ55_RS14665	COG1263	PTS System
EPJ55_RS14665	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EPJ55_RS14665	COG2190	(PTS) system
EPJ55_RS14685	COG2211	Major facilitator Superfamily
EPJ55_RS14725	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
EPJ55_RS14730	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
EPJ55_RS14735	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EPJ55_RS14735	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EPJ55_RS14735	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
EPJ55_RS14740	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EPJ55_RS14745	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EPJ55_RS14755	COG3711	transcriptional antiterminator
EPJ55_RS14765	COG3775	system Galactitol-specific IIC component
EPJ55_RS14770	COG3414	Phosphotransferase system galactitol-specific IIB component
EPJ55_RS14780	COG1349	DNA-binding transcription factor activity
EPJ55_RS14790	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
EPJ55_RS14795	COG1649	PFAM Uncharacterised BCR, COG1649
EPJ55_RS14795	COG0726	polysaccharide deacetylase
EPJ55_RS14810	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
EPJ55_RS14835	COG2261	transglycosylase associated protein
EPJ55_RS14845	COG1393	Belongs to the ArsC family
EPJ55_RS14865	COG4512	PFAM Accessory gene regulator B
EPJ55_RS14885	COG0028	Belongs to the TPP enzyme family
EPJ55_RS14890	COG1959	2 iron, 2 sulfur cluster binding
EPJ55_RS14895	COG0028	Belongs to the TPP enzyme family
EPJ55_RS14905	COG2972	Histidine kinase
EPJ55_RS14920	COG1653	transport
EPJ55_RS14925	COG0395	ABC-type sugar transport system, permease component
EPJ55_RS14940	COG2207	Transcriptional regulator
EPJ55_RS14940	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EPJ55_RS14945	COG1132	(ABC) transporter
EPJ55_RS14950	COG1132	(ABC) transporter
EPJ55_RS14955	COG2188	Transcriptional regulator
EPJ55_RS14970	COG3732	PTS system glucitol sorbitol-specific
EPJ55_RS14975	COG3730	PTS system glucitol sorbitol-specific
EPJ55_RS14995	COG4975	Glucose uptake
EPJ55_RS15000	COG1869	D-ribose catabolic process
EPJ55_RS15010	COG1609	Transcriptional regulator
EPJ55_RS15025	COG1012	belongs to the aldehyde dehydrogenase family
EPJ55_RS15025	COG1454	alcohol dehydrogenase
EPJ55_RS15035	COG1695	Transcriptional regulator
EPJ55_RS15040	COG3479	Phenolic acid decarboxylase
EPJ55_RS15055	COG1307	EDD domain protein, DegV family
EPJ55_RS15095	COG0445	tRNA wobble uridine modification
EPJ55_RS15100	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
EPJ55_RS15105	COG1847	R3H domain protein
EPJ55_RS15110	COG0706	membrane insertase activity
EPJ55_RS15115	COG0594	ribonuclease P activity
EPJ55_RS15120	COG0230	Belongs to the bacterial ribosomal protein bL34 family