locus-tag	class	description
Lp900_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
Lp900_RS00010	COG0592	DNA-directed DNA polymerase activity
Lp900_RS00015	COG2501	S4 domain
Lp900_RS00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
Lp900_RS00025	COG0187	DNA topoisomerase II activity
Lp900_RS00035	COG0360	Binds together with S18 to 16S ribosomal RNA
Lp900_RS00040	COG0629	single-stranded DNA binding
Lp900_RS00045	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
Lp900_RS00055	COG0359	binds to the 23S rRNA
Lp900_RS00060	COG0305	Participates in initiation and elongation during chromosome replication
Lp900_RS00065	COG2814	Major facilitator Superfamily
Lp900_RS00070	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
Lp900_RS00075	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
Lp900_RS00080	COG4166	transmembrane transport
Lp900_RS00085	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
Lp900_RS00090	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
Lp900_RS00095	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
Lp900_RS00100	COG0297	glycogen (starch) synthase activity
Lp900_RS00105	COG0058	SHG alpha-glucan phosphorylase activity
Lp900_RS00110	COG3103	Sh3 type 3 domain protein
Lp900_RS00110	COG0366	Alpha amylase catalytic
Lp900_RS00120	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
Lp900_RS00125	COG1554	hydrolase, family 65, central catalytic
Lp900_RS00135	COG1278	Cold shock
Lp900_RS00150	COG0745	RESPONSE REGULATOR receiver
Lp900_RS00155	COG5002	protein histidine kinase activity
Lp900_RS00165	COG4853	Protein conserved in bacteria
Lp900_RS00170	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
Lp900_RS00175	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
Lp900_RS00180	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
Lp900_RS00190	COG1012	belongs to the aldehyde dehydrogenase family
Lp900_RS00195	COG1573	uracil-dna glycosylase
Lp900_RS00215	COG0431	NADPH-dependent FMN reductase
Lp900_RS00215	COG1053	succinate dehydrogenase
Lp900_RS00215	COG3976	FMN-binding domain protein
Lp900_RS00220	COG0471	metal ion transport
Lp900_RS00235	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
Lp900_RS00240	COG1028	Short-chain dehydrogenase reductase Sdr
Lp900_RS00250	COG0778	Nitroreductase
Lp900_RS00255	COG2508	Transcriptional regulator
Lp900_RS00260	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
Lp900_RS00265	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
Lp900_RS00275	COG2365	Tyrosine phosphatase family
Lp900_RS00280	COG2368	4-hydroxyphenylacetate
Lp900_RS00335	COG0604	alcohol dehydrogenase
Lp900_RS00350	COG2267	carboxylic ester hydrolase activity
Lp900_RS00355	COG3022	response to hydroperoxide
Lp900_RS00365	COG4166	transmembrane transport
Lp900_RS00390	COG1122	ATPase activity
Lp900_RS00395	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
Lp900_RS00400	COG0310	cobalt ion transport
Lp900_RS00405	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
Lp900_RS00410	COG3875	lactate racemase activity
Lp900_RS00415	COG1691	(AIR) carboxylase
Lp900_RS00420	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
Lp900_RS00425	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
Lp900_RS00430	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
Lp900_RS00435	COG1606	tRNA processing
Lp900_RS00445	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
Lp900_RS00450	COG0351	phosphomethylpyrimidine kinase
Lp900_RS00455	COG0352	thiamine-phosphate diphosphorylase activity
Lp900_RS00465	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
Lp900_RS00480	COG1113	amino acid transport
Lp900_RS00490	COG2267	carboxylic ester hydrolase activity
Lp900_RS00495	COG3513	CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
Lp900_RS00500	COG1518	maintenance of DNA repeat elements
Lp900_RS00515	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
Lp900_RS00525	COG1983	PspC domain protein
Lp900_RS00565	COG2807	transmembrane transport
Lp900_RS00570	COG0656	L-ascorbic acid biosynthetic process
Lp900_RS00575	COG0667	Aldo Keto reductase
Lp900_RS00605	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
Lp900_RS00610	COG1122	ATPase activity
Lp900_RS00615	COG4720	Psort location CytoplasmicMembrane, score
Lp900_RS00625	COG2188	Transcriptional regulator
Lp900_RS00650	COG1028	Short-chain dehydrogenase reductase Sdr
Lp900_RS00655	COG1131	(ABC) transporter
Lp900_RS00670	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
Lp900_RS00675	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
Lp900_RS00680	COG1309	transcriptional regulator
Lp900_RS00685	COG2376	Dihydroxyacetone kinase
Lp900_RS00690	COG2376	Dihydroxyacetone kinase
Lp900_RS00695	COG1461	Dihydroxyacetone kinase
Lp900_RS00700	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
Lp900_RS00705	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
Lp900_RS00710	COG1609	Transcriptional regulator
Lp900_RS00715	COG1609	Transcriptional regulator
Lp900_RS00720	COG0366	Alpha amylase catalytic
Lp900_RS00725	COG2182	Extracellular solute-binding protein
Lp900_RS00730	COG1175	transmembrane transport
Lp900_RS00735	COG3833	ABC-type maltose transport systems, permease component
Lp900_RS00745	COG0366	Alpha amylase catalytic
Lp900_RS00750	COG3842	ATPase activity
Lp900_RS00805	COG1757	Na H antiporter
Lp900_RS00830	COG4166	transmembrane transport
Lp900_RS00835	COG4166	transmembrane transport
Lp900_RS00845	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
Lp900_RS00850	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
Lp900_RS00855	COG0406	alpha-ribazole phosphatase activity
Lp900_RS00860	COG0667	Aldo Keto reductase
Lp900_RS00890	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
Lp900_RS00895	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
Lp900_RS00900	COG0488	(ABC) transporter
Lp900_RS00915	COG4172	Belongs to the ABC transporter superfamily
Lp900_RS00925	COG0386	Belongs to the glutathione peroxidase family
Lp900_RS00935	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
Lp900_RS00950	COG0363	glucosamine-6-phosphate deaminase activity
Lp900_RS00960	COG2213	PTS system mannitol-specific
Lp900_RS00970	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
Lp900_RS00975	COG0246	Mannitol dehydrogenase
Lp900_RS00985	COG3118	belongs to the thioredoxin family
Lp900_RS01015	COG0431	NADPH-dependent FMN reductase
Lp900_RS01020	COG1045	serine acetyltransferase
Lp900_RS01025	COG0626	cystathionine gamma-synthase activity
Lp900_RS01030	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
Lp900_RS01055	COG2188	Transcriptional regulator
Lp900_RS01060	COG0366	Alpha amylase catalytic
Lp900_RS01065	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
Lp900_RS01065	COG2190	(PTS) system
Lp900_RS01065	COG1263	PTS System
Lp900_RS01070	COG2190	(PTS) system
Lp900_RS01070	COG1263	PTS System
Lp900_RS01070	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
Lp900_RS01080	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
Lp900_RS01085	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
Lp900_RS01090	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
Lp900_RS01100	COG0163	prenyltransferase activity
Lp900_RS01110	COG1959	2 iron, 2 sulfur cluster binding
Lp900_RS01115	COG1309	transcriptional regulator
Lp900_RS01120	COG1914	H( )-stimulated, divalent metal cation uptake system
Lp900_RS01140	COG2814	Major facilitator Superfamily
Lp900_RS01155	COG5002	protein histidine kinase activity
Lp900_RS01160	COG0745	RESPONSE REGULATOR receiver
Lp900_RS01170	COG1737	Transcriptional regulator
Lp900_RS01175	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
Lp900_RS01190	COG1316	TRANSCRIPTIONal
Lp900_RS01195	COG0277	FAD linked oxidase domain protein
Lp900_RS01205	COG2357	RelA SpoT domain protein
Lp900_RS01215	COG1033	growth of symbiont in host cell
Lp900_RS01215	COG2409	Drug exporters of the RND superfamily
Lp900_RS01220	COG2818	Glycosylase
Lp900_RS01230	COG0577	efflux transmembrane transporter activity
Lp900_RS01235	COG1136	(ABC) transporter
Lp900_RS01255	COG0741	lytic transglycosylase activity
Lp900_RS01260	COG1388	LysM domain
Lp900_RS01260	COG3942	CHAP domain
Lp900_RS01290	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
Lp900_RS01300	COG1846	Transcriptional regulator
Lp900_RS01305	COG1252	NADH dehydrogenase
Lp900_RS01345	COG3842	ATPase activity
Lp900_RS01375	COG1725	Transcriptional regulator
Lp900_RS01380	COG1131	(ABC) transporter
Lp900_RS01390	COG1454	alcohol dehydrogenase
Lp900_RS01390	COG1012	belongs to the aldehyde dehydrogenase family
Lp900_RS01425	COG1268	BioY protein
Lp900_RS01440	COG0436	Aminotransferase
Lp900_RS01450	COG1682	transport, permease protein
Lp900_RS01455	COG1134	teichoic acid transport
Lp900_RS01470	COG2814	Major facilitator Superfamily
Lp900_RS01475	COG0004	ammonium transporteR
Lp900_RS01495	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
Lp900_RS01505	COG3759	membrane
Lp900_RS01510	COG1881	PFAM PEBP family protein
Lp900_RS01540	COG0300	oxidoreductase activity
Lp900_RS01560	COG1125	glycine betaine transport
Lp900_RS01570	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
Lp900_RS01580	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
Lp900_RS01675	COG0110	maltose O-acetyltransferase activity
Lp900_RS01695	COG0561	phosphatase activity
Lp900_RS01700	COG1114	Component of the transport system for branched-chain amino acids
Lp900_RS01740	COG0463	Glycosyl transferase, family 2
Lp900_RS01770	COG3279	Response regulator of the LytR AlgR family
Lp900_RS01835	COG3973	AAA domain
Lp900_RS01840	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
Lp900_RS01845	COG0180	Tryptophanyl-tRNA synthetase
Lp900_RS01850	COG2188	Transcriptional regulator
Lp900_RS01855	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
Lp900_RS01870	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
Lp900_RS01875	COG2723	6-phospho-beta-galactosidase activity
Lp900_RS01880	COG1940	carbohydrate kinase activity
Lp900_RS01890	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
Lp900_RS01905	COG0248	Ppx GppA phosphatase
Lp900_RS01920	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
Lp900_RS01925	COG1801	Protein of unknown function DUF72
Lp900_RS01935	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
Lp900_RS01935	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
Lp900_RS01940	COG2814	Major facilitator Superfamily
Lp900_RS01945	COG0084	hydrolase, TatD family'
Lp900_RS01950	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
Lp900_RS01955	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
Lp900_RS01960	COG4466	Protein conserved in bacteria
Lp900_RS01965	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
Lp900_RS01975	COG1073	alpha beta
Lp900_RS01980	COG1121	(ABC) transporter
Lp900_RS01985	COG1321	iron dependent repressor
Lp900_RS01985	COG1108	ABC-type Mn2 Zn2 transport systems permease components
Lp900_RS02010	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
Lp900_RS02015	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
Lp900_RS02025	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
Lp900_RS02045	COG1078	dGTPase activity
Lp900_RS02050	COG0095	Lipoate-protein ligase
Lp900_RS02060	COG3343	RNA polymerase activity
Lp900_RS02065	COG0504	CTP synthase activity
Lp900_RS02070	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
Lp900_RS02075	COG0814	amino acid
Lp900_RS02080	COG1760	l-serine dehydratase
Lp900_RS02085	COG1760	l-serine dehydratase
Lp900_RS02100	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
Lp900_RS02105	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
Lp900_RS02110	COG0254	rRNA binding
Lp900_RS02120	COG3764	Sortase (surface protein transpeptidase)
Lp900_RS02125	COG1704	LemA family
Lp900_RS02130	COG0501	Belongs to the peptidase M48B family
Lp900_RS02140	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
Lp900_RS02150	COG0736	holo-[acyl-carrier-protein] synthase activity
Lp900_RS02155	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
Lp900_RS02160	COG2337	Toxic component of a toxin-antitoxin (TA) module
Lp900_RS02165	COG3158	transport of potassium into the cell
Lp900_RS02185	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
Lp900_RS02190	COG0505	Belongs to the CarA family
Lp900_RS02195	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
Lp900_RS02200	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
Lp900_RS02205	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
Lp900_RS02210	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
Lp900_RS02215	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
Lp900_RS02235	COG0039	L-malate dehydrogenase activity
Lp900_RS02240	COG0193	aminoacyl-tRNA hydrolase activity
Lp900_RS02245	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
Lp900_RS02250	COG2244	polysaccharide biosynthetic process
Lp900_RS02255	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
Lp900_RS02265	COG1098	S1 RNA binding domain
Lp900_RS02270	COG0037	tRNA processing
Lp900_RS02285	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
Lp900_RS02290	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
Lp900_RS02295	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
Lp900_RS02335	COG3104	oligopeptide transport
Lp900_RS02385	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
Lp900_RS02395	COG2188	Transcriptional regulator
Lp900_RS02405	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
Lp900_RS02410	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
Lp900_RS02425	COG2183	response to ionizing radiation
Lp900_RS02430	COG3091	SprT-like family
Lp900_RS02435	COG0460	homoserine dehydrogenase
Lp900_RS02440	COG0083	homoserine kinase activity
Lp900_RS02455	COG0582	viral genome integration into host DNA
Lp900_RS02475	COG3715	PTS system
Lp900_RS02480	COG3716	PTS system mannose fructose sorbose family IID component
Lp900_RS02490	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
Lp900_RS02490	COG3933	PFAM sigma-54 factor interaction domain-containing protein
Lp900_RS02495	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
Lp900_RS02495	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
Lp900_RS02500	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
Lp900_RS02500	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
Lp900_RS02505	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
Lp900_RS02515	COG0439	Biotin carboxylase
Lp900_RS02525	COG0825	malonyl-CoA metabolic process
Lp900_RS02530	COG1316	TRANSCRIPTIONal
Lp900_RS02540	COG0697	spore germination
Lp900_RS02545	COG0588	phosphoglycerate mutase activity
Lp900_RS02560	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
Lp900_RS02570	COG0756	dUTP diphosphatase activity
Lp900_RS02580	COG4956	integral membrane protein (PIN domain superfamily)
Lp900_RS02585	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
Lp900_RS02590	COG0215	cysteine-tRNA ligase activity
Lp900_RS02595	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
Lp900_RS02600	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
Lp900_RS02615	COG0267	Belongs to the bacterial ribosomal protein bL33 family
Lp900_RS02625	COG0250	Participates in transcription elongation, termination and antitermination
Lp900_RS02635	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
Lp900_RS02640	COG0081	regulation of translation
Lp900_RS02645	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
Lp900_RS02650	COG0222	ribosome binding
Lp900_RS02670	COG1611	Belongs to the LOG family
Lp900_RS02680	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
Lp900_RS02685	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
Lp900_RS02690	COG2813	Specifically methylates the guanine in position
Lp900_RS02705	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
Lp900_RS02710	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
Lp900_RS02715	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
Lp900_RS02725	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
Lp900_RS02730	COG3870	Protein conserved in bacteria
Lp900_RS02735	COG0470	DNA polymerase III
Lp900_RS02740	COG4467	Involved in initiation control of chromosome replication
Lp900_RS02755	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
Lp900_RS02765	COG3639	organic phosphonate transmembrane transporter activity
Lp900_RS02775	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
Lp900_RS02785	COG1214	PFAM Peptidase M22, glycoprotease
Lp900_RS02790	COG0456	acetyltransferase
Lp900_RS02795	COG0456	acetyltransferase
Lp900_RS02800	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
Lp900_RS02805	COG0488	(ABC) transporter
Lp900_RS02810	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
Lp900_RS02825	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
Lp900_RS02830	COG0459	protein refolding
Lp900_RS02835	COG0531	amino acid
Lp900_RS02840	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
Lp900_RS02845	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
Lp900_RS02850	COG1739	Uncharacterized protein family UPF0029
Lp900_RS02855	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
Lp900_RS02870	COG0653	protein targeting
Lp900_RS02885	COG0745	RESPONSE REGULATOR receiver
Lp900_RS02890	COG5002	protein histidine kinase activity
Lp900_RS02895	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
Lp900_RS02900	COG0573	inorganic phosphate transmembrane transporter activity
Lp900_RS02905	COG0581	inorganic phosphate transmembrane transporter activity
Lp900_RS02910	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
Lp900_RS02915	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
Lp900_RS02920	COG0704	Plays a role in the regulation of phosphate uptake
Lp900_RS02925	COG1983	PspC domain protein
Lp900_RS02930	COG1950	PFAM Membrane protein of
Lp900_RS02935	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
Lp900_RS02940	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
Lp900_RS02945	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
Lp900_RS02950	COG1210	Utp--glucose-1-phosphate uridylyltransferase
Lp900_RS02960	COG0446	pyridine nucleotide-disulphide oxidoreductase
Lp900_RS02965	COG0492	ferredoxin-NADP+ reductase activity
Lp900_RS02970	COG2323	membrane
Lp900_RS02980	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
Lp900_RS02990	COG0446	pyridine nucleotide-disulphide oxidoreductase
Lp900_RS03000	COG2814	Major facilitator Superfamily
Lp900_RS03010	COG0556	nucleotide-excision repair
Lp900_RS03015	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
Lp900_RS03020	COG1854	S-ribosylhomocysteine lyase activity
Lp900_RS03025	COG0137	argininosuccinate synthase activity
Lp900_RS03030	COG0165	Argininosuccinate lyase
Lp900_RS03040	COG1660	Displays ATPase and GTPase activities
Lp900_RS03050	COG1481	regulation of sporulation
Lp900_RS03060	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
Lp900_RS03065	COG0740	serine-type endopeptidase activity
Lp900_RS03075	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
Lp900_RS03080	COG2390	Transcriptional regulator
Lp900_RS03090	COG0126	phosphoglycerate kinase activity
Lp900_RS03095	COG0149	triose-phosphate isomerase activity
Lp900_RS03100	COG0148	phosphopyruvate hydratase activity
Lp900_RS03110	COG0038	chloride channel
Lp900_RS03115	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
Lp900_RS03125	COG0557	exoribonuclease II activity
Lp900_RS03130	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
Lp900_RS03140	COG0765	amino acid transport
Lp900_RS03145	COG1126	abc transporter atp-binding protein
Lp900_RS03155	COG0561	phosphatase activity
Lp900_RS03160	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
Lp900_RS03165	COG0280	phosphate acetyltransferase
Lp900_RS03170	COG0802	atpase or kinase
Lp900_RS03185	COG0708	Exodeoxyribonuclease III
Lp900_RS03195	COG0812	UDP-N-acetylmuramate dehydrogenase activity
Lp900_RS03200	COG0025	NhaP-type Na H and K H
Lp900_RS03225	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
Lp900_RS03230	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
Lp900_RS03240	COG0561	phosphatase activity
Lp900_RS03250	COG2017	converts alpha-aldose to the beta-anomer
Lp900_RS03265	COG0778	Nitroreductase
Lp900_RS03280	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
Lp900_RS03295	COG1393	Belongs to the ArsC family
Lp900_RS03310	COG0477	Major facilitator Superfamily
Lp900_RS03315	COG0248	Ppx GppA phosphatase
Lp900_RS03320	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
Lp900_RS03330	COG3475	LICD family
Lp900_RS03345	COG2252	PERMEase
Lp900_RS03350	COG0028	Belongs to the TPP enzyme family
Lp900_RS03355	COG0196	riboflavin kinase activity
Lp900_RS03360	COG0028	Belongs to the TPP enzyme family
Lp900_RS03365	COG2267	carboxylic ester hydrolase activity
Lp900_RS03375	COG2755	lipolytic protein G-D-S-L family
Lp900_RS03375	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
Lp900_RS03380	COG2936	dipeptidyl-peptidase activity
Lp900_RS03395	COG0531	amino acid
Lp900_RS03420	COG0194	GDP metabolic process
Lp900_RS03425	COG0735	belongs to the Fur family
Lp900_RS03440	COG0546	phosphoglycolate phosphatase activity
Lp900_RS03445	COG0436	Aminotransferase
Lp900_RS03450	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
Lp900_RS03465	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
Lp900_RS03470	COG0765	amino acid transport
Lp900_RS03475	COG0765	amino acid transport
Lp900_RS03480	COG1263	PTS System
Lp900_RS03480	COG2190	(PTS) system
Lp900_RS03480	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
Lp900_RS03490	COG1263	PTS System
Lp900_RS03490	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
Lp900_RS03495	COG3394	polysaccharide catabolic process
Lp900_RS03500	COG0531	amino acid
Lp900_RS03505	COG1846	Transcriptional regulator
Lp900_RS03535	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
Lp900_RS03545	COG2076	Multidrug Resistance protein
Lp900_RS03560	COG0588	phosphoglycerate mutase activity
Lp900_RS03565	COG0475	glutathione-regulated potassium exporter activity
Lp900_RS03565	COG0569	domain protein
Lp900_RS03570	COG0456	acetyltransferase
Lp900_RS03570	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
Lp900_RS03575	COG3711	transcriptional antiterminator
Lp900_RS03580	COG2190	(PTS) system
Lp900_RS03580	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
Lp900_RS03580	COG1263	PTS System
Lp900_RS03585	COG2723	6-phospho-beta-galactosidase activity
Lp900_RS03590	COG0586	Pfam SNARE associated Golgi protein
Lp900_RS03600	COG3973	AAA domain
Lp900_RS03605	COG2070	2-Nitropropane dioxygenase
Lp900_RS03610	COG1072	(Pantothenic acid kinase))
Lp900_RS03615	COG0519	Catalyzes the synthesis of GMP from XMP
Lp900_RS03615	COG0518	GMP synthase (glutamine-hydrolyzing) activity
Lp900_RS03625	COG1396	sequence-specific DNA binding
Lp900_RS03635	COG1266	CAAX protease self-immunity
Lp900_RS03640	COG1733	regulation of RNA biosynthetic process
Lp900_RS03645	COG2814	Major facilitator Superfamily
Lp900_RS03660	COG2755	lipolytic protein G-D-S-L family
Lp900_RS03660	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
Lp900_RS03665	COG2261	transglycosylase associated protein
Lp900_RS03680	COG1302	Protein conserved in bacteria
Lp900_RS03710	COG0308	aminopeptidase N
Lp900_RS03715	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
Lp900_RS03760	COG0572	uridine kinase
Lp900_RS03775	COG0583	DNA-binding transcription factor activity
Lp900_RS03780	COG1053	succinate dehydrogenase
Lp900_RS03790	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
Lp900_RS03795	COG0017	Asparaginyl-tRNA synthetase
Lp900_RS03800	COG2502	aspartate--ammonia ligase
Lp900_RS03805	COG4690	dipeptidase activity
Lp900_RS03820	COG0514	ATP-dependent DNA helicase (RecQ)
Lp900_RS03825	COG0564	pseudouridine synthase activity
Lp900_RS03830	COG0640	Transcriptional regulator
Lp900_RS03880	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
Lp900_RS03885	COG0527	aspartate kinase activity
Lp900_RS03890	COG0367	asparagine synthase
Lp900_RS03920	COG2814	Major facilitator Superfamily
Lp900_RS03940	COG1278	Cold shock
Lp900_RS03945	COG2966	Psort location CytoplasmicMembrane, score
Lp900_RS03955	COG1316	TRANSCRIPTIONal
Lp900_RS03975	COG1959	2 iron, 2 sulfur cluster binding
Lp900_RS03980	COG0028	Belongs to the TPP enzyme family
Lp900_RS03985	COG0833	amino acid
Lp900_RS04000	COG1428	Deoxynucleoside kinase
Lp900_RS04005	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
Lp900_RS04050	COG4463	regulation of RNA biosynthetic process
Lp900_RS04055	COG0542	response to heat
Lp900_RS04065	COG0085	RNA polymerase activity
Lp900_RS04070	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
Lp900_RS04075	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
Lp900_RS04080	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
Lp900_RS04085	COG0049	tRNA binding
Lp900_RS04090	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
Lp900_RS04095	COG0051	transcription antitermination factor activity, RNA binding
Lp900_RS04100	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
Lp900_RS04105	COG0088	Forms part of the polypeptide exit tunnel
Lp900_RS04110	COG0089	rRNA binding
Lp900_RS04115	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
Lp900_RS04120	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
Lp900_RS04125	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
Lp900_RS04130	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
Lp900_RS04135	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
Lp900_RS04140	COG0255	Belongs to the universal ribosomal protein uL29 family
Lp900_RS04145	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
Lp900_RS04150	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
Lp900_RS04155	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
Lp900_RS04160	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
Lp900_RS04165	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
Lp900_RS04170	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
Lp900_RS04175	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
Lp900_RS04180	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
Lp900_RS04185	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
Lp900_RS04190	COG1841	ribosomal large subunit assembly
Lp900_RS04195	COG0200	Binds to the 23S rRNA
Lp900_RS04205	COG0563	adenylate kinase activity
Lp900_RS04210	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
Lp900_RS04215	COG0257	Belongs to the bacterial ribosomal protein bL36 family
Lp900_RS04220	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
Lp900_RS04225	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
Lp900_RS04230	COG0202	RNA polymerase activity
Lp900_RS04235	COG0203	ribosomal protein L17
Lp900_RS04260	COG4939	FMN-binding domain protein
Lp900_RS04270	COG1122	ATPase activity
Lp900_RS04275	COG1122	ATPase activity
Lp900_RS04285	COG0101	tRNA pseudouridine synthase activity
Lp900_RS04290	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
Lp900_RS04295	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
Lp900_RS04315	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
Lp900_RS04320	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
Lp900_RS04325	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
Lp900_RS04330	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
Lp900_RS04340	COG2151	metal-sulfur cluster biosynthetic enzyme
Lp900_RS04345	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
Lp900_RS04355	COG1917	Cupin 2, conserved barrel domain protein
Lp900_RS04355	COG4977	sequence-specific DNA binding
Lp900_RS04360	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
Lp900_RS04365	COG1121	(ABC) transporter
Lp900_RS04370	COG1108	ABC-type Mn2 Zn2 transport systems permease components
Lp900_RS04375	COG0803	Belongs to the bacterial solute-binding protein 9 family
Lp900_RS04385	COG0039	L-malate dehydrogenase activity
Lp900_RS04390	COG0471	metal ion transport
Lp900_RS04410	COG3052	prosthetic group binding
Lp900_RS04425	COG2826	transposase and inactivated derivatives, IS30 family
Lp900_RS04450	COG0114	fumarate hydratase activity
Lp900_RS04455	COG1053	succinate dehydrogenase
Lp900_RS04465	COG0583	DNA-binding transcription factor activity
Lp900_RS04470	COG0583	DNA-binding transcription factor activity
Lp900_RS04475	COG0281	malic enzyme
Lp900_RS04485	COG0531	amino acid
Lp900_RS04490	COG4684	Psort location CytoplasmicMembrane, score
Lp900_RS04505	COG1271	oxidase subunit
Lp900_RS04510	COG1294	oxidase, subunit
Lp900_RS04515	COG4988	ABC transporter
Lp900_RS04520	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
Lp900_RS04535	COG0142	geranyltranstransferase activity
Lp900_RS04550	COG1705	Flagellar rod assembly protein muramidase FlgJ
Lp900_RS04555	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
Lp900_RS04560	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
Lp900_RS04565	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
Lp900_RS04575	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
Lp900_RS04580	COG4851	CamS sex pheromone cAM373 precursor
Lp900_RS04585	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
Lp900_RS04590	COG0154	amidase activity
Lp900_RS04595	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
Lp900_RS04600	COG1597	lipid kinase activity
Lp900_RS04605	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
Lp900_RS04620	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
Lp900_RS04630	COG1737	Transcriptional regulator
Lp900_RS04645	COG1278	Cold shock
Lp900_RS04650	COG0673	inositol 2-dehydrogenase activity
Lp900_RS04655	COG0513	Belongs to the DEAD box helicase family
Lp900_RS04670	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
Lp900_RS04695	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
Lp900_RS04705	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
Lp900_RS04715	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
Lp900_RS04725	COG3475	LICD family
Lp900_RS04775	COG2137	regulation of response to DNA damage stimulus
Lp900_RS04780	COG3557	Belongs to the UPF0374 family
Lp900_RS04810	COG0628	permease
Lp900_RS04815	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
Lp900_RS04825	COG1070	Carbohydrate kinase
Lp900_RS04830	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
Lp900_RS04835	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
Lp900_RS04840	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
Lp900_RS04880	COG4166	transmembrane transport
Lp900_RS04885	COG0601	transmembrane transport
Lp900_RS04890	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
Lp900_RS04895	COG0444	Belongs to the ABC transporter superfamily
Lp900_RS04900	COG4608	Belongs to the ABC transporter superfamily
Lp900_RS04910	COG0582	viral genome integration into host DNA
Lp900_RS04915	COG0542	response to heat
Lp900_RS04935	COG0438	transferase activity, transferring glycosyl groups
Lp900_RS04940	COG0438	transferase activity, transferring glycosyl groups
Lp900_RS04950	COG1686	Belongs to the peptidase S11 family
Lp900_RS04955	COG0436	Aminotransferase
Lp900_RS04960	COG4703	Protein of unknown function (DUF1797)
Lp900_RS04965	COG1368	sulfuric ester hydrolase activity
Lp900_RS05050	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
Lp900_RS05070	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
Lp900_RS05080	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
Lp900_RS05085	COG0833	amino acid
Lp900_RS05090	COG2040	homocysteine
Lp900_RS05095	COG0438	transferase activity, transferring glycosyl groups
Lp900_RS05105	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
Lp900_RS05110	COG0477	Major facilitator Superfamily
Lp900_RS05125	COG0438	transferase activity, transferring glycosyl groups
Lp900_RS05140	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
Lp900_RS05150	COG0495	leucyl-tRNA aminoacylation
Lp900_RS05155	COG2244	polysaccharide biosynthetic process
Lp900_RS05160	COG1187	pseudouridine synthase activity
Lp900_RS05165	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
Lp900_RS05170	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
Lp900_RS05180	COG3842	ATPase activity
Lp900_RS05185	COG1175	transmembrane transport
Lp900_RS05190	COG0395	ABC-type sugar transport system, permease component
Lp900_RS05200	COG0584	glycerophosphoryl diester phosphodiesterase
Lp900_RS05205	COG1428	Deoxynucleoside kinase
Lp900_RS05210	COG1970	mechanosensitive ion channel activity
Lp900_RS05215	COG1511	domain protein
Lp900_RS05215	COG1511	domain protein
Lp900_RS05245	COG2378	regulation of single-species biofilm formation
Lp900_RS05250	COG0596	Alpha beta hydrolase
Lp900_RS05260	COG0789	Transcriptional regulator
Lp900_RS05270	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
Lp900_RS05275	COG0789	Transcriptional regulator
Lp900_RS05285	COG0697	spore germination
Lp900_RS05290	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
Lp900_RS05305	COG1902	pentaerythritol trinitrate reductase activity
Lp900_RS05320	COG0561	phosphatase activity
Lp900_RS05335	COG3279	Response regulator of the LytR AlgR family
Lp900_RS05355	COG1846	Transcriptional regulator
Lp900_RS05370	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
Lp900_RS05405	COG0646	methionine synthase
Lp900_RS05405	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
Lp900_RS05410	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
Lp900_RS05420	COG2046	Belongs to the sulfate adenylyltransferase family
Lp900_RS05425	COG0529	Catalyzes the synthesis of activated sulfate
Lp900_RS05430	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
Lp900_RS05440	COG0471	metal ion transport
Lp900_RS05440	COG3273	potassium ion transport
Lp900_RS05445	COG0534	Mate efflux family protein
Lp900_RS05465	COG2153	protein acetylation
Lp900_RS05470	COG0018	arginyl-trna synthetase
Lp900_RS05480	COG0577	efflux transmembrane transporter activity
Lp900_RS05480	COG1136	(ABC) transporter
Lp900_RS05500	COG1447	Phosphotransferase system cellobiose-specific component IIA
Lp900_RS05505	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
Lp900_RS05510	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
Lp900_RS05515	COG2723	6-phospho-beta-galactosidase activity
Lp900_RS05530	COG1376	ErfK ybiS ycfS ynhG family protein
Lp900_RS05535	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
Lp900_RS05540	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
Lp900_RS05550	COG0436	Aminotransferase
Lp900_RS05555	COG1438	arginine binding
Lp900_RS05560	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
Lp900_RS05565	COG3679	Belongs to the UPF0342 family
Lp900_RS05570	COG0420	3'-5' exonuclease activity
Lp900_RS05575	COG4717	serine-type aminopeptidase activity
Lp900_RS05580	COG3481	metal-dependent phosphohydrolase, HD sub domain
Lp900_RS05595	COG0583	DNA-binding transcription factor activity
Lp900_RS05605	COG1053	succinate dehydrogenase
Lp900_RS05605	COG3976	FMN-binding domain protein
Lp900_RS05605	COG0431	NADPH-dependent FMN reductase
Lp900_RS05640	COG2217	Heavy metal translocating P-type atpase
Lp900_RS05645	COG0148	phosphopyruvate hydratase activity
Lp900_RS05655	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
Lp900_RS05660	COG0463	Glycosyl transferase, family 2
Lp900_RS05680	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
Lp900_RS05680	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
Lp900_RS05685	COG0307	riboflavin synthase, alpha
Lp900_RS05690	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
Lp900_RS05690	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
Lp900_RS05695	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
Lp900_RS05710	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
Lp900_RS05720	COG0446	pyridine nucleotide-disulphide oxidoreductase
Lp900_RS05750	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
Lp900_RS05760	COG0537	adenosine 5'-monophosphoramidase activity
Lp900_RS05765	COG1131	(ABC) transporter
Lp900_RS05770	COG4473	ABC transporter
Lp900_RS05775	COG0510	thiamine kinase activity
Lp900_RS05780	COG0220	tRNA (guanine-N7-)-methyltransferase activity
Lp900_RS05790	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
Lp900_RS05795	COG1674	ftsk spoiiie
Lp900_RS05800	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
Lp900_RS05825	COG0719	Fe-S assembly protein
Lp900_RS05830	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
Lp900_RS05840	COG0719	Fe-S assembly protein
Lp900_RS05845	COG2151	metal-sulfur cluster biosynthetic enzyme
Lp900_RS05860	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
Lp900_RS05860	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
Lp900_RS05865	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
Lp900_RS05870	COG0237	dephospho-CoA kinase activity
Lp900_RS05875	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
Lp900_RS05880	COG3611	Membrane attachment protein
Lp900_RS05885	COG1484	DNA-dependent DNA replication
Lp900_RS05890	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
Lp900_RS05895	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
Lp900_RS05900	COG0291	Belongs to the bacterial ribosomal protein bL35 family
Lp900_RS05905	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
Lp900_RS05915	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
Lp900_RS05920	COG0604	alcohol dehydrogenase
Lp900_RS05925	COG1733	regulation of RNA biosynthetic process
Lp900_RS05935	COG1215	transferase activity, transferring glycosyl groups
Lp900_RS05950	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
Lp900_RS05955	COG1534	Rna-binding protein
Lp900_RS05960	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
Lp900_RS05965	COG1713	HD superfamily hydrolase involved in NAD metabolism
Lp900_RS05970	COG0799	negative regulation of ribosome biogenesis
Lp900_RS05975	COG2226	methyltransferase
Lp900_RS05980	COG1323	Belongs to the UPF0348 family
Lp900_RS05990	COG0333	Belongs to the bacterial ribosomal protein bL32 family
Lp900_RS06005	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
Lp900_RS06010	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
Lp900_RS06015	COG0745	RESPONSE REGULATOR receiver
Lp900_RS06020	COG5002	protein histidine kinase activity
Lp900_RS06030	COG0419	ATPase involved in DNA repair
Lp900_RS06045	COG0706	membrane insertase activity
Lp900_RS06050	COG1254	Belongs to the acylphosphatase family
Lp900_RS06055	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
Lp900_RS06065	COG1733	regulation of RNA biosynthetic process
Lp900_RS06070	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
Lp900_RS06075	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
Lp900_RS06075	COG0072	phenylalanine-tRNA ligase activity
Lp900_RS06080	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
Lp900_RS06085	COG0572	uridine kinase
Lp900_RS06090	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
Lp900_RS06105	COG4841	protein insertion into membrane
Lp900_RS06115	COG0768	penicillin binding
Lp900_RS06120	COG0267	Belongs to the bacterial ribosomal protein bL33 family
Lp900_RS06125	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
Lp900_RS06130	COG0705	Rhomboid family
Lp900_RS06130	COG0457	Tetratricopeptide repeat
Lp900_RS06140	COG1940	carbohydrate kinase activity
Lp900_RS06160	COG0584	glycerophosphoryl diester phosphodiesterase
Lp900_RS06165	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
Lp900_RS06170	COG0789	Transcriptional regulator
Lp900_RS06225	COG0261	This protein binds to 23S rRNA in the presence of protein L20
Lp900_RS06235	COG0211	Belongs to the bacterial ribosomal protein bL27 family
Lp900_RS06240	COG0006	proline dipeptidase activity
Lp900_RS06245	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
Lp900_RS06250	COG1302	Protein conserved in bacteria
Lp900_RS06255	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
Lp900_RS06260	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
Lp900_RS06265	COG1570	exodeoxyribonuclease VII activity
Lp900_RS06270	COG1722	exodeoxyribonuclease VII activity
Lp900_RS06275	COG0142	geranyltranstransferase activity
Lp900_RS06280	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
Lp900_RS06285	COG1438	arginine binding
Lp900_RS06290	COG0497	DNA recombination
Lp900_RS06305	COG1732	Glycine betaine
Lp900_RS06320	COG0194	GDP metabolic process
Lp900_RS06325	COG1758	RNA polymerase activity
Lp900_RS06330	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
Lp900_RS06335	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
Lp900_RS06340	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
Lp900_RS06345	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
Lp900_RS06345	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
Lp900_RS06350	COG0631	protein serine/threonine phosphatase activity
Lp900_RS06355	COG0515	serine threonine protein kinase
Lp900_RS06355	COG2815	serine threonine protein kinase
Lp900_RS06360	COG1162	GTPase activity
Lp900_RS06365	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
Lp900_RS06370	COG1564	THIamine pyrophosphokinase
Lp900_RS06380	COG0227	Belongs to the bacterial ribosomal protein bL28 family
Lp900_RS06385	COG1302	Protein conserved in bacteria
Lp900_RS06390	COG1461	Dihydroxyacetone kinase
Lp900_RS06395	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
Lp900_RS06400	COG0416	fatty acid biosynthetic process
Lp900_RS06405	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
Lp900_RS06410	COG0571	ribonuclease III activity
Lp900_RS06415	COG1196	nuclear chromosome segregation
Lp900_RS06420	COG0552	protein localization to endoplasmic reticulum
Lp900_RS06425	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
Lp900_RS06430	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
Lp900_RS06435	COG0228	four-way junction DNA binding
Lp900_RS06440	COG1837	Belongs to the UPF0109 family
Lp900_RS06445	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
Lp900_RS06450	COG0336	Belongs to the RNA methyltransferase TrmD family
Lp900_RS06455	COG0335	large ribosomal subunit rRNA binding
Lp900_RS06475	COG1131	(ABC) transporter
Lp900_RS06490	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
Lp900_RS06490	COG0512	Glutamine amidotransferase of anthranilate synthase
Lp900_RS06495	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
Lp900_RS06500	COG0134	indole-3-glycerol-phosphate synthase activity
Lp900_RS06505	COG0135	phosphoribosylanthranilate isomerase activity
Lp900_RS06510	COG0133	tryptophan synthase activity
Lp900_RS06515	COG0159	tryptophan synthase activity
Lp900_RS06530	COG1063	alcohol dehydrogenase
Lp900_RS06540	COG0300	oxidoreductase activity
Lp900_RS06550	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
Lp900_RS06555	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
Lp900_RS06560	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
Lp900_RS06565	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
Lp900_RS06570	COG1028	Short-chain dehydrogenase reductase Sdr
Lp900_RS06575	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
Lp900_RS06590	COG0439	Biotin carboxylase
Lp900_RS06605	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
Lp900_RS06615	COG1811	Na channel or pump
Lp900_RS06620	COG0583	DNA-binding transcription factor activity
Lp900_RS06625	COG1607	acyl-coa hydrolase
Lp900_RS06630	COG1162	GTPase activity
Lp900_RS06660	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
Lp900_RS06665	COG3397	chitin binding
Lp900_RS06680	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
Lp900_RS06690	COG3152	Membrane
Lp900_RS06695	COG1597	lipid kinase activity
Lp900_RS06705	COG2261	transglycosylase associated protein
Lp900_RS06710	COG3237	CsbD-like
Lp900_RS06725	COG1942	4-Oxalocrotonate Tautomerase
Lp900_RS06760	COG0531	amino acid
Lp900_RS06765	COG0561	phosphatase activity
Lp900_RS06770	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
Lp900_RS06770	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
Lp900_RS06790	COG2017	converts alpha-aldose to the beta-anomer
Lp900_RS06795	COG1304	FMN binding
Lp900_RS06815	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
Lp900_RS06815	COG1199	ATP-dependent helicase activity
Lp900_RS06830	COG0017	Asparaginyl-tRNA synthetase
Lp900_RS06840	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
Lp900_RS06845	COG2011	ABC-type metal ion transport system permease component
Lp900_RS06850	COG1464	Belongs to the NlpA lipoprotein family
Lp900_RS06860	COG1177	transmembrane transport
Lp900_RS06865	COG1840	ABC-type Fe3 transport system, periplasmic component
Lp900_RS06885	COG3331	DNA recombination
Lp900_RS06890	COG4474	Belongs to the UPF0398 family
Lp900_RS06895	COG3599	regulation of cell shape
Lp900_RS06905	COG0116	Belongs to the methyltransferase superfamily
Lp900_RS06920	COG0477	Major facilitator Superfamily
Lp900_RS06925	COG1073	alpha beta
Lp900_RS06935	COG1216	Glycosyl transferase, family 2
Lp900_RS06955	COG1619	proteins homologs of microcin C7 resistance protein MccF
Lp900_RS06980	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
Lp900_RS06995	COG2759	Belongs to the formate--tetrahydrofolate ligase family
Lp900_RS07000	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
Lp900_RS07005	COG0564	pseudouridine synthase activity
Lp900_RS07010	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
Lp900_RS07015	COG0505	Belongs to the CarA family
Lp900_RS07020	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
Lp900_RS07030	COG5646	InterPro IPR014922
Lp900_RS07055	COG1131	(ABC) transporter
Lp900_RS07060	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
Lp900_RS07065	COG1293	RNA-binding protein homologous to eukaryotic snRNP
Lp900_RS07075	COG1307	EDD domain protein, DegV family
Lp900_RS07130	COG1113	amino acid transport
Lp900_RS07145	COG1620	l-lactate permease
Lp900_RS07155	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
Lp900_RS07165	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
Lp900_RS07180	COG1846	Transcriptional regulator
Lp900_RS07220	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
Lp900_RS07225	COG1227	inorganic diphosphatase activity
Lp900_RS07230	COG0583	DNA-binding transcription factor activity
Lp900_RS07240	COG0187	DNA topoisomerase II activity
Lp900_RS07245	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
Lp900_RS07255	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
Lp900_RS07260	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
Lp900_RS07265	COG4974	Belongs to the 'phage' integrase family
Lp900_RS07270	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
Lp900_RS07275	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
Lp900_RS07280	COG0758	DNA mediated transformation
Lp900_RS07285	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
Lp900_RS07290	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
Lp900_RS07295	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
Lp900_RS07300	COG0583	DNA-binding transcription factor activity
Lp900_RS07320	COG2814	Major facilitator Superfamily
Lp900_RS07325	COG0793	Belongs to the peptidase S41A family
Lp900_RS07325	COG3409	Peptidoglycan-binding domain 1 protein
Lp900_RS07330	COG4479	Belongs to the UPF0346 family
Lp900_RS07335	COG4698	Protein conserved in bacteria
Lp900_RS07340	COG2755	lipolytic protein G-D-S-L family
Lp900_RS07345	COG1307	EDD domain protein, DegV family
Lp900_RS07350	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
Lp900_RS07355	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
Lp900_RS07360	COG0488	(ABC) transporter
Lp900_RS07370	COG0617	tRNA 3'-terminal CCA addition
Lp900_RS07375	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
Lp900_RS07380	COG0561	phosphatase activity
Lp900_RS07385	COG0457	Tetratricopeptide repeat
Lp900_RS07395	COG1160	GTP binding
Lp900_RS07400	COG0539	negative regulation of cytoplasmic translation
Lp900_RS07405	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
Lp900_RS07415	COG0514	ATP-dependent DNA helicase (RecQ)
Lp900_RS07425	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
Lp900_RS07430	COG1187	pseudouridine synthase activity
Lp900_RS07435	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
Lp900_RS07440	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
Lp900_RS07450	COG4974	Belongs to the 'phage' integrase family
Lp900_RS07455	COG2996	Protein conserved in bacteria
Lp900_RS07470	COG0205	6-phosphofructokinase activity
Lp900_RS07475	COG0587	DNA-directed DNA polymerase activity
Lp900_RS07485	COG0542	response to heat
Lp900_RS07495	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
Lp900_RS07500	COG2384	SAM-dependent methyltransferase
Lp900_RS07525	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
Lp900_RS07525	COG0574	Belongs to the PEP-utilizing enzyme family
Lp900_RS07535	COG1846	Transcriptional regulator
Lp900_RS07555	COG2217	Heavy metal translocating P-type atpase
Lp900_RS07565	COG0477	Major facilitator Superfamily
Lp900_RS07575	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
Lp900_RS07585	COG1349	DNA-binding transcription factor activity
Lp900_RS07615	COG0546	phosphoglycolate phosphatase activity
Lp900_RS07645	COG0583	DNA-binding transcription factor activity
Lp900_RS07650	COG0604	alcohol dehydrogenase
Lp900_RS07660	COG0446	pyridine nucleotide-disulphide oxidoreductase
Lp900_RS07665	COG2197	response regulator
Lp900_RS07670	COG4585	Histidine kinase
Lp900_RS07680	COG1131	(ABC) transporter
Lp900_RS07690	COG0519	Catalyzes the synthesis of GMP from XMP
Lp900_RS07705	COG1131	(ABC) transporter
Lp900_RS07725	COG1131	(ABC) transporter
Lp900_RS07730	COG1725	Transcriptional regulator
Lp900_RS07735	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
Lp900_RS07740	COG0358	DNA primase activity
Lp900_RS07745	COG0751	glycine-tRNA ligase activity
Lp900_RS07750	COG0752	glycyl-tRNA synthetase alpha subunit
Lp900_RS07755	COG1381	Involved in DNA repair and RecF pathway recombination
Lp900_RS07760	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
Lp900_RS07765	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
Lp900_RS07770	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
Lp900_RS07775	COG1702	phosphate starvation-inducible protein PhoH
Lp900_RS07785	COG1610	YqeY-like protein
Lp900_RS07790	COG0828	Belongs to the bacterial ribosomal protein bS21 family
Lp900_RS07795	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
Lp900_RS07805	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
Lp900_RS07815	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
Lp900_RS07825	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
Lp900_RS07830	COG0124	histidyl-tRNA synthetase
Lp900_RS07835	COG4991	sh3 domain protein
Lp900_RS07835	COG3103	Sh3 type 3 domain protein
Lp900_RS07835	COG0860	N-Acetylmuramoyl-L-alanine amidase
Lp900_RS07840	COG3001	Fructosamine kinase
Lp900_RS07845	COG0546	phosphoglycolate phosphatase activity
Lp900_RS07850	COG1490	D-aminoacyl-tRNA deacylase activity
Lp900_RS07855	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
Lp900_RS07865	COG1385	rRNA (uridine-N3-)-methyltransferase activity
Lp900_RS07870	COG2264	protein methyltransferase activity
Lp900_RS07875	COG2094	Belongs to the DNA glycosylase MPG family
Lp900_RS07900	COG0582	viral genome integration into host DNA
Lp900_RS07905	COG0481	GTPase activity
Lp900_RS07910	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
Lp900_RS07915	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
Lp900_RS07920	COG1696	Membrane protein involved in D-alanine export
Lp900_RS07925	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
Lp900_RS07935	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
Lp900_RS07940	COG0484	heat shock protein binding
Lp900_RS07945	COG0443	Heat shock 70 kDa protein
Lp900_RS07950	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
Lp900_RS07955	COG1420	regulation of RNA biosynthetic process
Lp900_RS07960	COG3527	Alpha-acetolactate decarboxylase
Lp900_RS07965	COG0196	riboflavin kinase activity
Lp900_RS07970	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
Lp900_RS07975	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
Lp900_RS07980	COG0287	Prephenate dehydrogenase
Lp900_RS07985	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
Lp900_RS07995	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
Lp900_RS08000	COG0738	Major facilitator superfamily
Lp900_RS08005	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
Lp900_RS08010	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
Lp900_RS08020	COG2740	Nucleic-acid-binding protein implicated in transcription termination
Lp900_RS08025	COG0195	Participates in both transcription termination and antitermination
Lp900_RS08030	COG0779	Required for maturation of 30S ribosomal subunits
Lp900_RS08035	COG2176	DNA-directed DNA polymerase activity
Lp900_RS08040	COG0442	prolyl-tRNA aminoacylation
Lp900_RS08045	COG0750	zinc metalloprotease
Lp900_RS08050	COG4589	Belongs to the CDS family
Lp900_RS08055	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
Lp900_RS08060	COG0233	cytoplasmic translational termination
Lp900_RS08065	COG0528	UMP kinase activity
Lp900_RS08070	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
Lp900_RS08075	COG0052	Belongs to the universal ribosomal protein uS2 family
Lp900_RS08090	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
Lp900_RS08095	COG2827	Endonuclease containing a URI domain
Lp900_RS08100	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
Lp900_RS08105	COG0204	Acyl-transferase
Lp900_RS08110	COG3763	UPF0154 protein
Lp900_RS08115	COG4224	UPF0291 protein
Lp900_RS08120	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
Lp900_RS08135	COG3425	synthase
Lp900_RS08150	COG0463	Glycosyl transferase, family 2
Lp900_RS08215	COG0393	Putative heavy-metal-binding
Lp900_RS08230	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
Lp900_RS08235	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
Lp900_RS08235	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
Lp900_RS08240	COG5416	Lipopolysaccharide assembly protein A domain
Lp900_RS08245	COG0300	oxidoreductase activity
Lp900_RS08250	COG1234	tRNA 3'-trailer cleavage
Lp900_RS08260	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
Lp900_RS08265	COG1349	DNA-binding transcription factor activity
Lp900_RS08270	COG1105	Belongs to the carbohydrate kinase PfkB family
Lp900_RS08275	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
Lp900_RS08275	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
Lp900_RS08275	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
Lp900_RS08280	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
Lp900_RS08305	COG0297	glycogen (starch) synthase activity
Lp900_RS08310	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
Lp900_RS08315	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
Lp900_RS08325	COG0489	protein tyrosine kinase activity
Lp900_RS08335	COG0322	excinuclease ABC activity
Lp900_RS08340	COG1126	abc transporter atp-binding protein
Lp900_RS08345	COG0765	amino acid transport
Lp900_RS08365	COG0218	Necessary for normal cell division and for the maintenance of normal septation
Lp900_RS08370	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
Lp900_RS08375	COG0544	peptidyl-prolyl cis-trans isomerase activity
Lp900_RS08380	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
Lp900_RS08405	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
Lp900_RS08410	COG0268	Binds directly to 16S ribosomal RNA
Lp900_RS08415	COG1466	dna polymerase III delta subunit
Lp900_RS08420	COG2333	competence protein COMEC
Lp900_RS08420	COG0658	competence protein
Lp900_RS08425	COG2131	deaminase
Lp900_RS08430	COG1596	polysaccharide export
Lp900_RS08430	COG1555	photosystem II stabilization
Lp900_RS08435	COG3480	Lon protease (S16) C-terminal proteolytic domain
Lp900_RS08440	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
Lp900_RS08445	COG0742	ribosomal rna small subunit methyltransferase
Lp900_RS08450	COG4471	UPF0298 protein
Lp900_RS08455	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
Lp900_RS08460	COG0772	Belongs to the SEDS family
Lp900_RS08490	COG1217	gtp-binding protein TYPA
Lp900_RS08495	COG0483	inositol monophosphate 1-phosphatase activity
Lp900_RS08500	COG4476	Belongs to the UPF0223 family
Lp900_RS08505	COG0039	L-malate dehydrogenase activity
Lp900_RS08530	COG0242	peptide deformylase activity
Lp900_RS08540	COG5503	Protein of unknown function (DUF1447)
Lp900_RS08545	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
Lp900_RS08550	COG1597	lipid kinase activity
Lp900_RS08560	COG1388	LysM domain
Lp900_RS08560	COG3584	3D domain protein
Lp900_RS08565	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
Lp900_RS08570	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
Lp900_RS08605	COG0569	domain protein
Lp900_RS08610	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
Lp900_RS08615	COG0482	sulfurtransferase activity
Lp900_RS08625	COG1104	cysteine desulfurase activity
Lp900_RS08630	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
Lp900_RS08640	COG0494	nUDIX hydrolase
Lp900_RS08645	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
Lp900_RS08650	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
Lp900_RS08655	COG3599	regulation of cell shape
Lp900_RS08665	COG0762	integral membrane protein
Lp900_RS08670	COG1799	cell septum assembly
Lp900_RS08685	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
Lp900_RS08690	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
Lp900_RS08695	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
Lp900_RS08700	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
Lp900_RS08705	COG0768	penicillin binding
Lp900_RS08715	COG0275	rRNA processing
Lp900_RS08720	COG2001	Belongs to the MraZ family
Lp900_RS08740	COG1674	ftsk spoiiie
Lp900_RS08745	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
Lp900_RS08755	COG1114	Component of the transport system for branched-chain amino acids
Lp900_RS08770	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
Lp900_RS08775	COG0628	permease
Lp900_RS08785	COG2706	6-phosphogluconolactonase activity
Lp900_RS08790	COG3142	Participates in the control of copper homeostasis
Lp900_RS08795	COG0564	pseudouridine synthase activity
Lp900_RS08800	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
Lp900_RS08805	COG2357	RelA SpoT domain protein
Lp900_RS08815	COG1164	Oligoendopeptidase f
Lp900_RS08825	COG4862	establishment of competence for transformation
Lp900_RS08830	COG1393	Belongs to the ArsC family
Lp900_RS08835	COG1234	tRNA 3'-trailer cleavage
Lp900_RS08975	COG1098	S1 RNA binding domain
Lp900_RS08985	COG0586	Pfam SNARE associated Golgi protein
Lp900_RS08995	COG0647	UMP catabolic process
Lp900_RS09000	COG4470	Protein conserved in bacteria
Lp900_RS09005	COG0737	Belongs to the 5'-nucleotidase family
Lp900_RS09015	COG1113	amino acid transport
Lp900_RS09020	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
Lp900_RS09025	COG0827	DNA restriction-modification system
Lp900_RS09055	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
Lp900_RS09065	COG0217	transcriptional regulatory protein
Lp900_RS09080	COG1609	Transcriptional regulator
Lp900_RS09090	COG0006	proline dipeptidase activity
Lp900_RS09095	COG0789	Transcriptional regulator
Lp900_RS09110	COG0668	transmembrane transport
Lp900_RS09115	COG1473	amidohydrolase
Lp900_RS09120	COG2171	N-acyltransferase activity
Lp900_RS09125	COG0517	IMP dehydrogenase activity
Lp900_RS09135	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
Lp900_RS09140	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
Lp900_RS09145	COG1719	4-vinyl reductase, 4VR
Lp900_RS09150	COG3118	belongs to the thioredoxin family
Lp900_RS09155	COG1193	negative regulation of DNA recombination
Lp900_RS09165	COG3906	Belongs to the UPF0473 family
Lp900_RS09170	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
Lp900_RS09175	COG4472	Bacterial protein of unknown function (DUF965)
Lp900_RS09180	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
Lp900_RS09185	COG0513	Belongs to the DEAD box helicase family
Lp900_RS09190	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
Lp900_RS09195	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
Lp900_RS09200	COG1862	Preprotein translocase
Lp900_RS09205	COG0343	queuine tRNA-ribosyltransferase activity
Lp900_RS09210	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
Lp900_RS09215	COG2255	four-way junction helicase activity
Lp900_RS09220	COG0632	four-way junction helicase activity
Lp900_RS09240	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
Lp900_RS09245	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
Lp900_RS09250	COG1692	metallophosphoesterase
Lp900_RS09255	COG1418	mRNA catabolic process
Lp900_RS09260	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
Lp900_RS09265	COG1058	Belongs to the CinA family
Lp900_RS09265	COG1546	Belongs to the CinA family
Lp900_RS09270	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
Lp900_RS09275	COG1426	Protein conserved in bacteria
Lp900_RS09280	COG0612	Peptidase, M16
Lp900_RS09285	COG0612	Peptidase, M16
Lp900_RS09290	COG0527	aspartate kinase activity
Lp900_RS09295	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
Lp900_RS09300	COG1126	abc transporter atp-binding protein
Lp900_RS09305	COG0765	amino acid transport
Lp900_RS09310	COG2894	cell division
Lp900_RS09315	COG0850	regulation of cytokinetic process
Lp900_RS09325	COG1792	Involved in formation and maintenance of cell shape
Lp900_RS09330	COG1077	Cell shape determining protein MreB Mrl
Lp900_RS09335	COG2003	Belongs to the UPF0758 family
Lp900_RS09340	COG0285	dihydrofolate synthase activity
Lp900_RS09345	COG0525	valine-tRNA ligase activity
Lp900_RS09355	COG2918	glutathione biosynthetic process
Lp900_RS09355	COG1181	Belongs to the D-alanine--D-alanine ligase family
Lp900_RS09360	COG0301	tRNA thio-modification
Lp900_RS09365	COG1104	cysteine desulfurase activity
Lp900_RS09370	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
Lp900_RS09375	COG1956	GAF domain-containing protein
Lp900_RS09380	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
Lp900_RS09385	COG4493	Belongs to the UPF0637 family
Lp900_RS09400	COG0640	Transcriptional regulator
Lp900_RS09405	COG0366	Alpha amylase catalytic
Lp900_RS09415	COG3716	PTS system mannose fructose sorbose family IID component
Lp900_RS09420	COG3715	PTS system
Lp900_RS09425	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
Lp900_RS09430	COG1609	Transcriptional regulator
Lp900_RS09435	COG2918	glutathione biosynthetic process
Lp900_RS09435	COG0189	ligase activity
Lp900_RS09440	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
Lp900_RS09455	COG0589	response to stress
Lp900_RS09475	COG1181	Belongs to the D-alanine--D-alanine ligase family
Lp900_RS09495	COG1464	Belongs to the NlpA lipoprotein family
Lp900_RS09500	COG2011	ABC-type metal ion transport system permease component
Lp900_RS09505	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
Lp900_RS09510	COG0509	glycine decarboxylation via glycine cleavage system
Lp900_RS09515	COG0772	Belongs to the SEDS family
Lp900_RS09525	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
Lp900_RS09530	COG1077	Cell shape determining protein MreB Mrl
Lp900_RS09540	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
Lp900_RS09545	COG0355	proton-transporting ATP synthase activity, rotational mechanism
Lp900_RS09550	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
Lp900_RS09555	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
Lp900_RS09560	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
Lp900_RS09565	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
Lp900_RS09570	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
Lp900_RS09575	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
Lp900_RS09580	COG0356	it plays a direct role in the translocation of protons across the membrane
Lp900_RS09585	COG2233	PERMEase
Lp900_RS09595	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
Lp900_RS09600	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
Lp900_RS09605	COG0009	L-threonylcarbamoyladenylate synthase
Lp900_RS09610	COG2890	protein-(glutamine-N5) methyltransferase activity
Lp900_RS09615	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
Lp900_RS09620	COG1435	thymidine kinase activity
Lp900_RS09625	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
Lp900_RS09630	COG3442	glutamine amidotransferase
Lp900_RS09635	COG1482	cell wall glycoprotein biosynthetic process
Lp900_RS09640	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
Lp900_RS09650	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
Lp900_RS09670	COG1132	(ABC) transporter
Lp900_RS09685	COG0726	polysaccharide deacetylase
Lp900_RS09725	COG4695	Portal protein
Lp900_RS09790	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
Lp900_RS09820	COG4886	Leucine-rich repeat (LRR) protein
Lp900_RS09820	COG4932	domain protein
Lp900_RS09835	COG1132	(ABC) transporter
Lp900_RS09845	COG1136	(ABC) transporter
Lp900_RS09845	COG0577	efflux transmembrane transporter activity
Lp900_RS09855	COG0166	Belongs to the GPI family
Lp900_RS09860	COG4975	Glucose uptake
Lp900_RS09865	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
Lp900_RS09870	COG3850	Histidine kinase
Lp900_RS09870	COG5002	protein histidine kinase activity
Lp900_RS09875	COG0745	RESPONSE REGULATOR receiver
Lp900_RS09880	COG2848	UPF0210 protein
Lp900_RS09885	COG3830	Belongs to the UPF0237 family
Lp900_RS09910	COG0477	Major facilitator Superfamily
Lp900_RS09930	COG0791	NLP P60 protein
Lp900_RS09935	COG1522	sequence-specific DNA binding
Lp900_RS09955	COG0488	(ABC) transporter
Lp900_RS09975	COG1263	PTS System
Lp900_RS09975	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
Lp900_RS09975	COG2190	(PTS) system
Lp900_RS09980	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
Lp900_RS09985	COG1307	EDD domain protein, DegV family
Lp900_RS09995	COG2873	o-acetylhomoserine
Lp900_RS10000	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
Lp900_RS10010	COG4120	Belongs to the binding-protein-dependent transport system permease family
Lp900_RS10020	COG0446	pyridine nucleotide-disulphide oxidoreductase
Lp900_RS10025	COG2084	Dehydrogenase
Lp900_RS10030	COG0861	Integral membrane protein TerC family
Lp900_RS10035	COG0110	maltose O-acetyltransferase activity
Lp900_RS10040	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
Lp900_RS10045	COG0140	phosphoribosyl-ATP diphosphatase activity
Lp900_RS10050	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
Lp900_RS10055	COG0107	imidazoleglycerol-phosphate synthase activity
Lp900_RS10060	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
Lp900_RS10065	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
Lp900_RS10070	COG0131	Imidazoleglycerol-phosphate dehydratase
Lp900_RS10075	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
Lp900_RS10080	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
Lp900_RS10085	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
Lp900_RS10090	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
Lp900_RS10115	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
Lp900_RS10130	COG3548	integral membrane protein
Lp900_RS10150	COG1368	sulfuric ester hydrolase activity
Lp900_RS10160	COG0492	ferredoxin-NADP+ reductase activity
Lp900_RS10170	COG4932	domain protein
Lp900_RS10175	COG2326	polyphosphate kinase activity
Lp900_RS10180	COG0778	Nitroreductase
Lp900_RS10190	COG0328	RNA-DNA hybrid ribonuclease activity
Lp900_RS10195	COG4975	Glucose uptake
Lp900_RS10200	COG1940	carbohydrate kinase activity
Lp900_RS10210	COG1349	DNA-binding transcription factor activity
Lp900_RS10215	COG1882	Formate acetyltransferase
Lp900_RS10235	COG1609	Transcriptional regulator
Lp900_RS10240	COG1737	Transcriptional regulator
Lp900_RS10245	COG0673	inositol 2-dehydrogenase activity
Lp900_RS10250	COG0673	inositol 2-dehydrogenase activity
Lp900_RS10255	COG0025	NhaP-type Na H and K H
Lp900_RS10260	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
Lp900_RS10265	COG1335	isochorismatase
Lp900_RS10275	COG1131	(ABC) transporter
Lp900_RS10280	COG1725	Transcriptional regulator
Lp900_RS10325	COG0028	Belongs to the TPP enzyme family
Lp900_RS10335	COG1073	alpha beta
Lp900_RS10340	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
Lp900_RS10345	COG0626	cystathionine gamma-synthase activity
Lp900_RS10375	COG0095	Lipoate-protein ligase
Lp900_RS10380	COG1705	Flagellar rod assembly protein muramidase FlgJ
Lp900_RS10385	COG0589	response to stress
Lp900_RS10390	COG0564	pseudouridine synthase activity
Lp900_RS10405	COG4640	response to antibiotic
Lp900_RS10410	COG1396	sequence-specific DNA binding
Lp900_RS10425	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
Lp900_RS10435	COG2188	Transcriptional regulator
Lp900_RS10440	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
Lp900_RS10450	COG1418	mRNA catabolic process
Lp900_RS10480	COG1253	flavin adenine dinucleotide binding
Lp900_RS10485	COG1780	Probably involved in ribonucleotide reductase function
Lp900_RS10490	COG0025	NhaP-type Na H and K H
Lp900_RS10495	COG2814	Major facilitator Superfamily
Lp900_RS10500	COG0789	Transcriptional regulator
Lp900_RS10505	COG0604	alcohol dehydrogenase
Lp900_RS10515	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
Lp900_RS10520	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
Lp900_RS10525	COG0436	Aminotransferase
Lp900_RS10530	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
Lp900_RS10540	COG0583	DNA-binding transcription factor activity
Lp900_RS10545	COG0702	epimerase
Lp900_RS10555	COG1074	ATP-dependent DNA helicase activity
Lp900_RS10560	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
Lp900_RS10570	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
Lp900_RS10575	COG0284	orotidine-5'-phosphate decarboxylase activity
Lp900_RS10580	COG0167	dihydroorotate dehydrogenase activity
Lp900_RS10585	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
Lp900_RS10590	COG0505	Belongs to the CarA family
Lp900_RS10595	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
Lp900_RS10600	COG0540	Belongs to the ATCase OTCase family
Lp900_RS10605	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
Lp900_RS10610	COG2508	Transcriptional regulator
Lp900_RS10615	COG2233	PERMEase
Lp900_RS10620	COG2252	PERMEase
Lp900_RS10640	COG1215	transferase activity, transferring glycosyl groups
Lp900_RS10650	COG0151	Belongs to the GarS family
Lp900_RS10655	COG0138	bifunctional purine biosynthesis protein purh
Lp900_RS10660	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
Lp900_RS10665	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
Lp900_RS10675	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
Lp900_RS10680	COG0047	phosphoribosylformylglycinamidine synthase activity
Lp900_RS10685	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
Lp900_RS10690	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
Lp900_RS10695	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
Lp900_RS10710	COG1053	succinate dehydrogenase
Lp900_RS10710	COG0431	NADPH-dependent FMN reductase
Lp900_RS10710	COG3976	FMN-binding domain protein
Lp900_RS10715	COG3976	FMN-binding domain protein
Lp900_RS10715	COG0431	NADPH-dependent FMN reductase
Lp900_RS10715	COG1053	succinate dehydrogenase
Lp900_RS10720	COG0095	Lipoate-protein ligase
Lp900_RS10725	COG2365	Tyrosine phosphatase family
Lp900_RS10745	COG1136	(ABC) transporter
Lp900_RS10760	COG1725	Transcriptional regulator
Lp900_RS10765	COG1131	(ABC) transporter
Lp900_RS10775	COG0589	response to stress
Lp900_RS10785	COG2246	polysaccharide biosynthetic process
Lp900_RS10800	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
Lp900_RS10820	COG0366	Alpha amylase catalytic
Lp900_RS10830	COG0561	phosphatase activity
Lp900_RS10840	COG0110	maltose O-acetyltransferase activity
Lp900_RS10845	COG0494	nUDIX hydrolase
Lp900_RS10880	COG1827	regulation of RNA biosynthetic process
Lp900_RS10885	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
Lp900_RS10890	COG1309	transcriptional regulator
Lp900_RS10900	COG1131	(ABC) transporter
Lp900_RS10905	COG3048	D-serine ammonia-lyase activity
Lp900_RS10910	COG2723	6-phospho-beta-galactosidase activity
Lp900_RS10915	COG2723	6-phospho-beta-galactosidase activity
Lp900_RS10920	COG1447	Phosphotransferase system cellobiose-specific component IIA
Lp900_RS10925	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
Lp900_RS10930	COG2188	Transcriptional regulator
Lp900_RS10935	COG1216	Glycosyl transferase, family 2
Lp900_RS10950	COG0561	phosphatase activity
Lp900_RS10955	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
Lp900_RS10980	COG0716	FMN binding
Lp900_RS11000	COG0710	3-dehydroquinate dehydratase activity
Lp900_RS11005	COG0531	amino acid
Lp900_RS11050	COG4720	Psort location CytoplasmicMembrane, score
Lp900_RS11055	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
Lp900_RS11070	COG4990	cell redox homeostasis
Lp900_RS11085	COG1811	Na channel or pump
Lp900_RS11090	COG0789	Transcriptional regulator
Lp900_RS11090	COG4978	Transcriptional regulator
Lp900_RS11105	COG0577	efflux transmembrane transporter activity
Lp900_RS11110	COG1136	(ABC) transporter
Lp900_RS11150	COG2814	Major facilitator Superfamily
Lp900_RS11160	COG2814	Major facilitator Superfamily
Lp900_RS11170	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
Lp900_RS11175	COG2855	membrane
Lp900_RS11180	COG0583	DNA-binding transcription factor activity
Lp900_RS11190	COG0438	transferase activity, transferring glycosyl groups
Lp900_RS11205	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
Lp900_RS11210	COG4152	abc transporter atp-binding protein
Lp900_RS11220	COG4221	oxidoreductase activity
Lp900_RS11235	COG0789	Transcriptional regulator
Lp900_RS11255	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
Lp900_RS11275	COG0456	acetyltransferase
Lp900_RS11300	COG0583	DNA-binding transcription factor activity
Lp900_RS11310	COG1063	alcohol dehydrogenase
Lp900_RS11315	COG1028	Short-chain dehydrogenase reductase Sdr
Lp900_RS11350	COG0656	L-ascorbic acid biosynthetic process
Lp900_RS11355	COG0583	DNA-binding transcription factor activity
Lp900_RS11380	COG0656	L-ascorbic acid biosynthetic process
Lp900_RS11400	COG0589	response to stress
Lp900_RS11405	COG0110	maltose O-acetyltransferase activity
Lp900_RS11410	COG1011	Hydrolase
Lp900_RS11425	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
Lp900_RS11435	COG0667	Aldo Keto reductase
Lp900_RS11440	COG1132	(ABC) transporter
Lp900_RS11445	COG1132	(ABC) transporter
Lp900_RS11450	COG2814	Major facilitator Superfamily
Lp900_RS11460	COG1511	domain protein
Lp900_RS11460	COG1511	domain protein
Lp900_RS11470	COG0640	Transcriptional regulator
Lp900_RS11500	COG0488	(ABC) transporter
Lp900_RS11505	COG0561	phosphatase activity
Lp900_RS11515	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
Lp900_RS11530	COG2267	carboxylic ester hydrolase activity
Lp900_RS11535	COG0531	amino acid
Lp900_RS11540	COG2270	Major facilitator Superfamily
Lp900_RS11580	COG2200	EAL domain
Lp900_RS11590	COG1328	CTP reductase activity
Lp900_RS11600	COG0242	peptide deformylase activity
Lp900_RS11610	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
Lp900_RS11625	COG0583	DNA-binding transcription factor activity
Lp900_RS11635	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
Lp900_RS11680	COG0697	spore germination
Lp900_RS11705	COG1940	carbohydrate kinase activity
Lp900_RS11710	COG1132	(ABC) transporter
Lp900_RS11720	COG0778	Nitroreductase
Lp900_RS11725	COG1263	PTS System
Lp900_RS11725	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
Lp900_RS11725	COG2190	(PTS) system
Lp900_RS11730	COG1116	anion transmembrane transporter activity
Lp900_RS11735	COG4120	Belongs to the binding-protein-dependent transport system permease family
Lp900_RS11770	COG0410	ABC transporter
Lp900_RS11785	COG0559	Belongs to the binding-protein-dependent transport system permease family
Lp900_RS11805	COG5549	protein import
Lp900_RS11805	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
Lp900_RS11810	COG2246	polysaccharide biosynthetic process
Lp900_RS11820	COG1914	H( )-stimulated, divalent metal cation uptake system
Lp900_RS11840	COG0640	Transcriptional regulator
Lp900_RS11850	COG1136	(ABC) transporter
Lp900_RS11850	COG0577	efflux transmembrane transporter activity
Lp900_RS11885	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
Lp900_RS11890	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
Lp900_RS11895	COG2723	6-phospho-beta-galactosidase activity
Lp900_RS11905	COG0789	Transcriptional regulator
Lp900_RS11910	COG0741	lytic transglycosylase activity
Lp900_RS11930	COG0803	Belongs to the bacterial solute-binding protein 9 family
Lp900_RS11955	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
Lp900_RS11970	COG4221	oxidoreductase activity
Lp900_RS12000	COG1028	Short-chain dehydrogenase reductase Sdr
Lp900_RS12020	COG1132	(ABC) transporter
Lp900_RS12030	COG1473	amidohydrolase
Lp900_RS12035	COG1028	Short-chain dehydrogenase reductase Sdr
Lp900_RS12050	COG0531	amino acid
Lp900_RS12070	COG2217	Heavy metal translocating P-type atpase
Lp900_RS12125	COG1063	alcohol dehydrogenase
Lp900_RS12165	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
Lp900_RS12180	COG1733	regulation of RNA biosynthetic process
Lp900_RS12185	COG2814	Major facilitator Superfamily
Lp900_RS12195	COG0367	asparagine synthase
Lp900_RS12200	COG3279	Response regulator of the LytR AlgR family
Lp900_RS12210	COG1309	transcriptional regulator
Lp900_RS12220	COG1012	belongs to the aldehyde dehydrogenase family
Lp900_RS12235	COG1733	regulation of RNA biosynthetic process
Lp900_RS12240	COG0300	oxidoreductase activity
Lp900_RS12260	COG4989	oxidoreductase activity
Lp900_RS12265	COG0477	Major facilitator Superfamily
Lp900_RS12275	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
Lp900_RS12280	COG1120	ATPase activity
Lp900_RS12285	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
Lp900_RS12290	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
Lp900_RS12295	COG1309	transcriptional regulator
Lp900_RS12305	COG0640	Transcriptional regulator
Lp900_RS12310	COG2814	Major facilitator Superfamily
Lp900_RS12315	COG4221	oxidoreductase activity
Lp900_RS12320	COG0110	maltose O-acetyltransferase activity
Lp900_RS12325	COG1028	Short-chain dehydrogenase reductase Sdr
Lp900_RS12360	COG0481	GTPase activity
Lp900_RS12370	COG2816	NAD+ diphosphatase activity
Lp900_RS12380	COG0431	NADPH-dependent FMN reductase
Lp900_RS12380	COG3976	FMN-binding domain protein
Lp900_RS12380	COG1053	succinate dehydrogenase
Lp900_RS12390	COG0783	Belongs to the Dps family
Lp900_RS12400	COG2723	6-phospho-beta-galactosidase activity
Lp900_RS12405	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
Lp900_RS12420	COG0789	Transcriptional regulator
Lp900_RS12440	COG0693	protein deglycase activity
Lp900_RS12455	COG1136	(ABC) transporter
Lp900_RS12455	COG0577	efflux transmembrane transporter activity
Lp900_RS12465	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
Lp900_RS12480	COG1376	ErfK ybiS ycfS ynhG family protein
Lp900_RS12485	COG0656	L-ascorbic acid biosynthetic process
Lp900_RS12500	COG0477	Major facilitator Superfamily
Lp900_RS12535	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
Lp900_RS12545	COG3414	Phosphotransferase system galactitol-specific IIB component
Lp900_RS12550	COG3775	system Galactitol-specific IIC component
Lp900_RS12560	COG1349	DNA-binding transcription factor activity
Lp900_RS12565	COG1028	Short-chain dehydrogenase reductase Sdr
Lp900_RS12570	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
Lp900_RS12575	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
Lp900_RS12580	COG3775	system Galactitol-specific IIC component
Lp900_RS12585	COG3414	Phosphotransferase system galactitol-specific IIB component
Lp900_RS12615	COG2226	methyltransferase
Lp900_RS12620	COG0588	phosphoglycerate mutase activity
Lp900_RS12625	COG0628	permease
Lp900_RS12630	COG1940	carbohydrate kinase activity
Lp900_RS12630	COG1846	Transcriptional regulator
Lp900_RS12640	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
Lp900_RS12650	COG2815	serine threonine protein kinase
Lp900_RS12650	COG0515	serine threonine protein kinase
Lp900_RS12685	COG1247	-acetyltransferase
Lp900_RS12690	COG1686	Belongs to the peptidase S11 family
Lp900_RS12710	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
Lp900_RS12715	COG0517	IMP dehydrogenase activity
Lp900_RS12715	COG0516	GMP reductase activity
Lp900_RS12725	COG0012	GTP binding
Lp900_RS12730	COG4481	Protein conserved in bacteria
Lp900_RS12735	COG1475	DNA binding
Lp900_RS12740	COG1192	Involved in chromosome partitioning
Lp900_RS12750	COG0357	Ribosomal RNA small subunit methyltransferase G
Lp900_RS12755	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
Lp900_RS12770	COG0583	DNA-binding transcription factor activity
Lp900_RS12775	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
Lp900_RS12780	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
Lp900_RS12785	COG0765	amino acid transport
Lp900_RS12790	COG1126	abc transporter atp-binding protein
Lp900_RS12795	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
Lp900_RS12820	COG1263	PTS System
Lp900_RS12820	COG2190	(PTS) system
Lp900_RS12820	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
Lp900_RS12825	COG0366	Alpha amylase catalytic
Lp900_RS12830	COG1609	Transcriptional regulator
Lp900_RS12840	COG0390	transport system, permease component
Lp900_RS12845	COG4619	ABC transporter
Lp900_RS12850	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
Lp900_RS12865	COG0561	phosphatase activity
Lp900_RS12880	COG1263	PTS System
Lp900_RS12880	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
Lp900_RS12880	COG2190	(PTS) system
Lp900_RS12910	COG0735	belongs to the Fur family
Lp900_RS12935	COG1380	Effector of murein hydrolase LrgA
Lp900_RS12945	COG1307	EDD domain protein, DegV family
Lp900_RS12955	COG2738	Putative neutral zinc metallopeptidase
Lp900_RS13010	COG5280	Phage tail tape measure protein TP901
Lp900_RS13010	COG3953	SLT domain
Lp900_RS13080	COG2826	transposase and inactivated derivatives, IS30 family
Lp900_RS13205	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
Lp900_RS13250	COG1233	COG1233 Phytoene dehydrogenase and related
Lp900_RS13255	COG1562	ergosterol biosynthetic process
Lp900_RS13265	COG1929	Belongs to the glycerate kinase type-1 family
Lp900_RS13280	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
Lp900_RS13285	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
Lp900_RS13290	COG0516	GMP reductase activity
Lp900_RS13295	COG2365	Tyrosine phosphatase family
Lp900_RS13300	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
Lp900_RS13315	COG0531	amino acid
Lp900_RS13320	COG3158	transport of potassium into the cell
Lp900_RS13325	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
Lp900_RS13330	COG0628	permease
Lp900_RS13335	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
Lp900_RS13350	COG1272	protein, Hemolysin III
Lp900_RS13355	COG0640	Transcriptional regulator
Lp900_RS13390	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
Lp900_RS13400	COG0302	gtp cyclohydrolase
Lp900_RS13405	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
Lp900_RS13420	COG0803	Belongs to the bacterial solute-binding protein 9 family
Lp900_RS13430	COG2814	Major facilitator Superfamily
Lp900_RS13460	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
Lp900_RS13465	COG1882	Formate acetyltransferase
Lp900_RS13470	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
Lp900_RS13475	COG2151	metal-sulfur cluster biosynthetic enzyme
Lp900_RS13480	COG4989	oxidoreductase activity
Lp900_RS13510	COG2217	Heavy metal translocating P-type atpase
Lp900_RS13520	COG2315	Protein conserved in bacteria
Lp900_RS13535	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
Lp900_RS13540	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
Lp900_RS13550	COG1757	Na H antiporter
Lp900_RS13555	COG1113	amino acid transport
Lp900_RS13565	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
Lp900_RS13580	COG1393	Belongs to the ArsC family
Lp900_RS13585	COG3189	MarR family transcriptional regulator
Lp900_RS13595	COG1194	a g-specific adenine glycosylase
Lp900_RS13610	COG0071	Belongs to the small heat shock protein (HSP20) family
Lp900_RS13635	COG0697	spore germination
Lp900_RS13650	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
Lp900_RS13675	COG0477	Major facilitator Superfamily
Lp900_RS13725	COG0737	Belongs to the 5'-nucleotidase family
Lp900_RS13735	COG0656	L-ascorbic acid biosynthetic process
Lp900_RS13755	COG1968	undecaprenyl-diphosphatase activity
Lp900_RS13760	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
Lp900_RS13795	COG2207	Transcriptional regulator
Lp900_RS13820	COG0076	glutamate decarboxylase activity
Lp900_RS13855	COG2226	methyltransferase
Lp900_RS13870	COG2217	Heavy metal translocating P-type atpase
Lp900_RS13875	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
Lp900_RS13880	COG3118	belongs to the thioredoxin family
Lp900_RS13885	COG1937	Protein conserved in bacteria
Lp900_RS13905	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
Lp900_RS13910	COG3590	peptidase
Lp900_RS13925	COG0446	pyridine nucleotide-disulphide oxidoreductase
Lp900_RS13975	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
Lp900_RS13985	COG1114	Component of the transport system for branched-chain amino acids
Lp900_RS13995	COG1874	Beta-galactosidase
Lp900_RS14000	COG1609	Transcriptional regulator
Lp900_RS14010	COG0477	Major facilitator Superfamily
Lp900_RS14030	COG2184	nucleotidyltransferase activity
Lp900_RS14035	COG2944	sequence-specific DNA binding
Lp900_RS14040	COG1609	Transcriptional regulator
Lp900_RS14045	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
Lp900_RS14050	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
Lp900_RS14055	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
Lp900_RS14075	COG2211	Major facilitator Superfamily
Lp900_RS14075	COG2190	(PTS) system
Lp900_RS14080	COG2017	converts alpha-aldose to the beta-anomer
Lp900_RS14085	COG1609	Transcriptional regulator
Lp900_RS14090	COG0667	Aldo Keto reductase
Lp900_RS14110	COG0710	3-dehydroquinate dehydratase activity
Lp900_RS14115	COG0738	Major facilitator superfamily
Lp900_RS14120	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
Lp900_RS14125	COG0583	DNA-binding transcription factor activity
Lp900_RS14130	COG0738	Major facilitator superfamily
Lp900_RS14140	COG2267	carboxylic ester hydrolase activity
Lp900_RS14145	COG2188	Transcriptional regulator
Lp900_RS14150	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
Lp900_RS14155	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
Lp900_RS14160	COG2971	BadF BadG BcrA BcrD
Lp900_RS14170	COG2723	6-phospho-beta-galactosidase activity
Lp900_RS14180	COG3711	transcriptional antiterminator
Lp900_RS14185	COG2723	6-phospho-beta-galactosidase activity
Lp900_RS14190	COG0431	NADPH-dependent FMN reductase
Lp900_RS14190	COG3976	FMN-binding domain protein
Lp900_RS14190	COG1053	succinate dehydrogenase
Lp900_RS14200	COG0318	PFAM AMP-dependent synthetase and ligase
Lp900_RS14205	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
Lp900_RS14215	COG1960	acyl-CoA dehydrogenase activity
Lp900_RS14230	COG2223	nitrite transmembrane transporter activity
Lp900_RS14235	COG0583	DNA-binding transcription factor activity
Lp900_RS14240	COG2723	6-phospho-beta-galactosidase activity
Lp900_RS14245	COG2190	(PTS) system
Lp900_RS14245	COG1263	PTS System
Lp900_RS14245	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
Lp900_RS14265	COG2211	Major facilitator Superfamily
Lp900_RS14280	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
Lp900_RS14295	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
Lp900_RS14315	COG3711	transcriptional antiterminator
Lp900_RS14330	COG1063	alcohol dehydrogenase
Lp900_RS14335	COG3775	system Galactitol-specific IIC component
Lp900_RS14340	COG3414	Phosphotransferase system galactitol-specific IIB component
Lp900_RS14350	COG1349	DNA-binding transcription factor activity
Lp900_RS14355	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
Lp900_RS14365	COG0110	maltose O-acetyltransferase activity
Lp900_RS14370	COG2160	L-arabinose isomerase activity
Lp900_RS14390	COG1609	Transcriptional regulator
Lp900_RS14395	COG1737	Transcriptional regulator
Lp900_RS14415	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
Lp900_RS14435	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
Lp900_RS14440	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
Lp900_RS14460	COG2261	transglycosylase associated protein
Lp900_RS14470	COG1393	Belongs to the ArsC family
Lp900_RS14490	COG4512	PFAM Accessory gene regulator B
Lp900_RS14505	COG1304	FMN binding
Lp900_RS14510	COG0028	Belongs to the TPP enzyme family
Lp900_RS14515	COG1959	2 iron, 2 sulfur cluster binding
Lp900_RS14520	COG0028	Belongs to the TPP enzyme family
Lp900_RS14535	COG0235	Class ii aldolase
Lp900_RS14540	COG4806	L-rhamnose isomerase
Lp900_RS14545	COG3254	rhamnose metabolic process
Lp900_RS14550	COG1070	Carbohydrate kinase
Lp900_RS14555	COG2814	Major facilitator Superfamily
Lp900_RS14560	COG2207	Transcriptional regulator
Lp900_RS14565	COG1349	DNA-binding transcription factor activity
Lp900_RS14580	COG3775	system Galactitol-specific IIC component
Lp900_RS14590	COG2814	Major facilitator Superfamily
Lp900_RS14595	COG0673	inositol 2-dehydrogenase activity
Lp900_RS14600	COG0673	inositol 2-dehydrogenase activity
Lp900_RS14610	COG1082	Xylose isomerase domain protein TIM barrel
Lp900_RS14615	COG0673	inositol 2-dehydrogenase activity
Lp900_RS14620	COG2814	Major facilitator Superfamily
Lp900_RS14625	COG0673	inositol 2-dehydrogenase activity
Lp900_RS14630	COG4702	Belongs to the UPF0303 family
Lp900_RS14635	COG0604	alcohol dehydrogenase
Lp900_RS14640	COG1957	nucleoside hydrolase
Lp900_RS14655	COG3732	PTS system glucitol sorbitol-specific
Lp900_RS14660	COG3730	PTS system glucitol sorbitol-specific
Lp900_RS14670	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
Lp900_RS14670	COG3711	transcriptional antiterminator
Lp900_RS14680	COG2723	6-phospho-beta-galactosidase activity
Lp900_RS14685	COG1940	carbohydrate kinase activity
Lp900_RS14690	COG0383	alpha-mannosidase activity
Lp900_RS14700	COG2188	Transcriptional regulator
Lp900_RS14710	COG3842	ATPase activity
Lp900_RS14720	COG2207	Transcriptional regulator
Lp900_RS14720	COG4753	response regulator
Lp900_RS14725	COG2972	Histidine kinase
Lp900_RS14735	COG0366	Alpha amylase catalytic
Lp900_RS14740	COG1653	transport
Lp900_RS14745	COG0395	ABC-type sugar transport system, permease component
Lp900_RS14760	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
Lp900_RS14760	COG2207	Transcriptional regulator
Lp900_RS14765	COG1132	(ABC) transporter
Lp900_RS14770	COG1132	(ABC) transporter
Lp900_RS14775	COG2188	Transcriptional regulator
Lp900_RS14790	COG3732	PTS system glucitol sorbitol-specific
Lp900_RS14795	COG3730	PTS system glucitol sorbitol-specific
Lp900_RS14815	COG4975	Glucose uptake
Lp900_RS14820	COG1869	D-ribose catabolic process
Lp900_RS14830	COG1609	Transcriptional regulator
Lp900_RS14835	COG1012	belongs to the aldehyde dehydrogenase family
Lp900_RS14835	COG1454	alcohol dehydrogenase
Lp900_RS14850	COG1695	Transcriptional regulator
Lp900_RS14855	COG3479	Phenolic acid decarboxylase
Lp900_RS14870	COG1307	EDD domain protein, DegV family
Lp900_RS14910	COG0445	tRNA wobble uridine modification
Lp900_RS14915	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
Lp900_RS14920	COG1847	R3H domain protein
Lp900_RS14930	COG4166	transmembrane transport
Lp900_RS14935	COG0706	membrane insertase activity
Lp900_RS14940	COG0594	ribonuclease P activity
Lp900_RS14945	COG0230	Belongs to the bacterial ribosomal protein bL34 family
Lp900_RS14950	COG1957	nucleoside hydrolase
Lp900_RS14955	COG0604	alcohol dehydrogenase
Lp900_RS14960	COG4702	Belongs to the UPF0303 family
Lp900_RS14965	COG0673	inositol 2-dehydrogenase activity
Lp900_RS14970	COG2814	Major facilitator Superfamily
Lp900_RS14975	COG0673	inositol 2-dehydrogenase activity
Lp900_RS14980	COG1082	Xylose isomerase domain protein TIM barrel
Lp900_RS14985	COG0673	inositol 2-dehydrogenase activity
Lp900_RS14990	COG0673	inositol 2-dehydrogenase activity
Lp900_RS14995	COG2814	Major facilitator Superfamily
Lp900_RS15010	COG2826	transposase and inactivated derivatives, IS30 family
Lp900_RS15060	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
Lp900_RS15075	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
Lp900_RS15080	COG2826	transposase and inactivated derivatives, IS30 family
Lp900_RS15100	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
Lp900_RS15100	COG0551	DNA topoisomerase type I activity
Lp900_RS15175	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
Lp900_RS15210	COG1192	Involved in chromosome partitioning
Lp900_RS15250	COG1113	amino acid transport
Lp900_RS15265	COG1192	Involved in chromosome partitioning
Lp900_RS15285	COG0477	Major facilitator Superfamily
Lp900_RS15320	COG2096	Adenosyltransferase
Lp900_RS15325	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
Lp900_RS15340	COG2161	toxin-antitoxin pair type II binding
Lp900_RS15415	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
Lp900_RS15420	COG2252	PERMEase
Lp900_RS15425	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
Lp900_RS15460	COG3716	PTS system mannose fructose sorbose family IID component
Lp900_RS15475	COG2826	transposase and inactivated derivatives, IS30 family
Lp900_RS15485	COG1113	amino acid transport
Lp900_RS15495	COG1192	Involved in chromosome partitioning
Lp900_RS15535	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
Lp900_RS15540	COG1846	Transcriptional regulator
Lp900_RS15560	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
Lp900_RS15565	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
Lp900_RS15570	COG4464	protein tyrosine phosphatase activity
Lp900_RS15575	COG0489	protein tyrosine kinase activity
Lp900_RS15590	COG2801	Transposase and inactivated derivatives
Lp900_RS15595	COG0438	transferase activity, transferring glycosyl groups
Lp900_RS15600	COG0728	peptidoglycan biosynthetic process
Lp900_RS15620	COG3475	LICD family
Lp900_RS15635	COG1216	Glycosyl transferase, family 2
Lp900_RS15690	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
Lp900_RS15735	COG0582	viral genome integration into host DNA