locus-tag	class	description
ASV54_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
ASV54_RS00010	COG0592	DNA-directed DNA polymerase activity
ASV54_RS00015	COG2501	S4 domain
ASV54_RS00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
ASV54_RS00025	COG0187	DNA topoisomerase II activity
ASV54_RS00035	COG0360	Binds together with S18 to 16S ribosomal RNA
ASV54_RS00040	COG0629	single-stranded DNA binding
ASV54_RS00045	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
ASV54_RS00055	COG0359	binds to the 23S rRNA
ASV54_RS00060	COG0305	Participates in initiation and elongation during chromosome replication
ASV54_RS00065	COG2814	Major facilitator Superfamily
ASV54_RS00070	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
ASV54_RS00075	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
ASV54_RS00080	COG4166	transmembrane transport
ASV54_RS00090	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
ASV54_RS00095	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
ASV54_RS00100	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
ASV54_RS00105	COG0297	glycogen (starch) synthase activity
ASV54_RS00110	COG0058	SHG alpha-glucan phosphorylase activity
ASV54_RS00115	COG0366	Alpha amylase catalytic
ASV54_RS00115	COG3103	Sh3 type 3 domain protein
ASV54_RS00125	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ASV54_RS00130	COG1554	hydrolase, family 65, central catalytic
ASV54_RS00140	COG1278	Cold shock
ASV54_RS00155	COG0745	RESPONSE REGULATOR receiver
ASV54_RS00160	COG5002	protein histidine kinase activity
ASV54_RS00170	COG4853	Protein conserved in bacteria
ASV54_RS00175	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
ASV54_RS00180	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ASV54_RS00185	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
ASV54_RS00195	COG1012	belongs to the aldehyde dehydrogenase family
ASV54_RS00205	COG1573	uracil-dna glycosylase
ASV54_RS00225	COG0431	NADPH-dependent FMN reductase
ASV54_RS00225	COG1053	succinate dehydrogenase
ASV54_RS00225	COG3976	FMN-binding domain protein
ASV54_RS00230	COG0471	metal ion transport
ASV54_RS00245	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
ASV54_RS00250	COG1028	Short-chain dehydrogenase reductase Sdr
ASV54_RS00260	COG0778	Nitroreductase
ASV54_RS00265	COG2508	Transcriptional regulator
ASV54_RS00275	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ASV54_RS00280	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
ASV54_RS00290	COG2365	Tyrosine phosphatase family
ASV54_RS00295	COG2368	4-hydroxyphenylacetate
ASV54_RS00315	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
ASV54_RS00350	COG0604	alcohol dehydrogenase
ASV54_RS00375	COG2267	carboxylic ester hydrolase activity
ASV54_RS00380	COG3022	response to hydroperoxide
ASV54_RS00390	COG4166	transmembrane transport
ASV54_RS00415	COG1122	ATPase activity
ASV54_RS00420	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
ASV54_RS00425	COG0310	cobalt ion transport
ASV54_RS00430	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
ASV54_RS00435	COG3875	lactate racemase activity
ASV54_RS00440	COG1691	(AIR) carboxylase
ASV54_RS00445	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
ASV54_RS00450	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
ASV54_RS00455	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
ASV54_RS00460	COG1606	tRNA processing
ASV54_RS00470	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
ASV54_RS00475	COG0351	phosphomethylpyrimidine kinase
ASV54_RS00480	COG0352	thiamine-phosphate diphosphorylase activity
ASV54_RS00490	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
ASV54_RS00505	COG1113	amino acid transport
ASV54_RS00520	COG2267	carboxylic ester hydrolase activity
ASV54_RS00525	COG3513	CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
ASV54_RS00530	COG1518	maintenance of DNA repeat elements
ASV54_RS00545	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
ASV54_RS00555	COG1983	PspC domain protein
ASV54_RS00595	COG2807	transmembrane transport
ASV54_RS00600	COG0656	L-ascorbic acid biosynthetic process
ASV54_RS00605	COG0667	Aldo Keto reductase
ASV54_RS00635	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
ASV54_RS00640	COG1122	ATPase activity
ASV54_RS00645	COG4720	Psort location CytoplasmicMembrane, score
ASV54_RS00655	COG2188	Transcriptional regulator
ASV54_RS00680	COG1028	Short-chain dehydrogenase reductase Sdr
ASV54_RS00685	COG1131	(ABC) transporter
ASV54_RS00700	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
ASV54_RS00705	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
ASV54_RS00710	COG1309	transcriptional regulator
ASV54_RS00715	COG2376	Dihydroxyacetone kinase
ASV54_RS00720	COG2376	Dihydroxyacetone kinase
ASV54_RS00725	COG1461	Dihydroxyacetone kinase
ASV54_RS00730	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
ASV54_RS00735	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
ASV54_RS00740	COG1609	Transcriptional regulator
ASV54_RS00745	COG1609	Transcriptional regulator
ASV54_RS00755	COG2182	Extracellular solute-binding protein
ASV54_RS00760	COG1175	transmembrane transport
ASV54_RS00765	COG3833	ABC-type maltose transport systems, permease component
ASV54_RS00775	COG0366	Alpha amylase catalytic
ASV54_RS00780	COG3842	ATPase activity
ASV54_RS00840	COG1757	Na H antiporter
ASV54_RS00865	COG4166	transmembrane transport
ASV54_RS00870	COG4166	transmembrane transport
ASV54_RS00880	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
ASV54_RS00885	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
ASV54_RS00890	COG0406	alpha-ribazole phosphatase activity
ASV54_RS00925	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
ASV54_RS00930	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
ASV54_RS00935	COG0488	(ABC) transporter
ASV54_RS00950	COG4172	Belongs to the ABC transporter superfamily
ASV54_RS00960	COG0386	Belongs to the glutathione peroxidase family
ASV54_RS00970	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
ASV54_RS00985	COG0363	glucosamine-6-phosphate deaminase activity
ASV54_RS00995	COG2213	PTS system mannitol-specific
ASV54_RS01005	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
ASV54_RS01010	COG0246	Mannitol dehydrogenase
ASV54_RS01020	COG3118	belongs to the thioredoxin family
ASV54_RS01050	COG0431	NADPH-dependent FMN reductase
ASV54_RS01055	COG1045	serine acetyltransferase
ASV54_RS01060	COG0626	cystathionine gamma-synthase activity
ASV54_RS01065	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
ASV54_RS01095	COG2188	Transcriptional regulator
ASV54_RS01100	COG0366	Alpha amylase catalytic
ASV54_RS01105	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ASV54_RS01105	COG2190	(PTS) system
ASV54_RS01105	COG1263	PTS System
ASV54_RS01110	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ASV54_RS01110	COG1263	PTS System
ASV54_RS01110	COG2190	(PTS) system
ASV54_RS01120	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
ASV54_RS01125	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
ASV54_RS01130	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
ASV54_RS01145	COG0163	prenyltransferase activity
ASV54_RS01155	COG1959	2 iron, 2 sulfur cluster binding
ASV54_RS01160	COG1309	transcriptional regulator
ASV54_RS01165	COG1914	H( )-stimulated, divalent metal cation uptake system
ASV54_RS01185	COG2814	Major facilitator Superfamily
ASV54_RS01200	COG5002	protein histidine kinase activity
ASV54_RS01205	COG0745	RESPONSE REGULATOR receiver
ASV54_RS01215	COG1737	Transcriptional regulator
ASV54_RS01220	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
ASV54_RS01235	COG1316	TRANSCRIPTIONal
ASV54_RS01240	COG0277	FAD linked oxidase domain protein
ASV54_RS01250	COG2357	RelA SpoT domain protein
ASV54_RS01260	COG2409	Drug exporters of the RND superfamily
ASV54_RS01260	COG1033	growth of symbiont in host cell
ASV54_RS01265	COG2818	Glycosylase
ASV54_RS01275	COG0577	efflux transmembrane transporter activity
ASV54_RS01280	COG1136	(ABC) transporter
ASV54_RS01295	COG0741	lytic transglycosylase activity
ASV54_RS01300	COG3942	CHAP domain
ASV54_RS01300	COG1388	LysM domain
ASV54_RS01330	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
ASV54_RS01340	COG1846	Transcriptional regulator
ASV54_RS01345	COG1252	NADH dehydrogenase
ASV54_RS01385	COG3842	ATPase activity
ASV54_RS01415	COG1725	Transcriptional regulator
ASV54_RS01420	COG1131	(ABC) transporter
ASV54_RS01430	COG1454	alcohol dehydrogenase
ASV54_RS01430	COG1012	belongs to the aldehyde dehydrogenase family
ASV54_RS01465	COG1268	BioY protein
ASV54_RS01480	COG0436	Aminotransferase
ASV54_RS01490	COG1682	transport, permease protein
ASV54_RS01495	COG1134	teichoic acid transport
ASV54_RS01510	COG2814	Major facilitator Superfamily
ASV54_RS01515	COG0004	ammonium transporteR
ASV54_RS01535	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
ASV54_RS01545	COG3759	membrane
ASV54_RS01550	COG1881	PFAM PEBP family protein
ASV54_RS01580	COG0300	oxidoreductase activity
ASV54_RS01600	COG1125	glycine betaine transport
ASV54_RS01610	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
ASV54_RS01620	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
ASV54_RS01675	COG0110	maltose O-acetyltransferase activity
ASV54_RS01685	COG0561	phosphatase activity
ASV54_RS01695	COG0561	phosphatase activity
ASV54_RS01700	COG1114	Component of the transport system for branched-chain amino acids
ASV54_RS01735	COG0475	glutathione-regulated potassium exporter activity
ASV54_RS01780	COG3290	protein histidine kinase activity
ASV54_RS01805	COG2274	protein secretion by the type I secretion system
ASV54_RS01845	COG3973	AAA domain
ASV54_RS01850	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
ASV54_RS01855	COG0180	Tryptophanyl-tRNA synthetase
ASV54_RS01860	COG2188	Transcriptional regulator
ASV54_RS01865	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
ASV54_RS01885	COG2723	6-phospho-beta-galactosidase activity
ASV54_RS01890	COG1940	carbohydrate kinase activity
ASV54_RS01900	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
ASV54_RS01915	COG0248	Ppx GppA phosphatase
ASV54_RS01930	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
ASV54_RS01935	COG1801	Protein of unknown function DUF72
ASV54_RS01945	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ASV54_RS01945	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ASV54_RS01950	COG2814	Major facilitator Superfamily
ASV54_RS01955	COG0084	hydrolase, TatD family'
ASV54_RS01960	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
ASV54_RS01965	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
ASV54_RS01970	COG4466	Protein conserved in bacteria
ASV54_RS01975	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
ASV54_RS01980	COG1073	alpha beta
ASV54_RS01985	COG1121	(ABC) transporter
ASV54_RS01990	COG1108	ABC-type Mn2 Zn2 transport systems permease components
ASV54_RS01990	COG1321	iron dependent repressor
ASV54_RS02020	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
ASV54_RS02025	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
ASV54_RS02035	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
ASV54_RS02055	COG1078	dGTPase activity
ASV54_RS02060	COG0095	Lipoate-protein ligase
ASV54_RS02070	COG3343	RNA polymerase activity
ASV54_RS02075	COG0504	CTP synthase activity
ASV54_RS02080	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
ASV54_RS02085	COG0814	amino acid
ASV54_RS02095	COG1760	l-serine dehydratase
ASV54_RS02100	COG1760	l-serine dehydratase
ASV54_RS02115	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
ASV54_RS02120	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
ASV54_RS02125	COG0254	rRNA binding
ASV54_RS02135	COG3764	Sortase (surface protein transpeptidase)
ASV54_RS02140	COG1704	LemA family
ASV54_RS02145	COG0501	Belongs to the peptidase M48B family
ASV54_RS02155	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
ASV54_RS02170	COG0736	holo-[acyl-carrier-protein] synthase activity
ASV54_RS02175	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
ASV54_RS02180	COG2337	Toxic component of a toxin-antitoxin (TA) module
ASV54_RS02185	COG3158	transport of potassium into the cell
ASV54_RS02190	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
ASV54_RS02195	COG0505	Belongs to the CarA family
ASV54_RS02200	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
ASV54_RS02205	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
ASV54_RS02210	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
ASV54_RS02215	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
ASV54_RS02220	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
ASV54_RS02235	COG2267	carboxylic ester hydrolase activity
ASV54_RS02255	COG0039	L-malate dehydrogenase activity
ASV54_RS02260	COG0193	aminoacyl-tRNA hydrolase activity
ASV54_RS02265	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
ASV54_RS02270	COG2244	polysaccharide biosynthetic process
ASV54_RS02275	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
ASV54_RS02285	COG1098	S1 RNA binding domain
ASV54_RS02290	COG0037	tRNA processing
ASV54_RS02305	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
ASV54_RS02310	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
ASV54_RS02315	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
ASV54_RS02355	COG3104	oligopeptide transport
ASV54_RS02405	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
ASV54_RS02415	COG2188	Transcriptional regulator
ASV54_RS02425	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
ASV54_RS02430	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
ASV54_RS02445	COG2183	response to ionizing radiation
ASV54_RS02450	COG3091	SprT-like family
ASV54_RS02455	COG0460	homoserine dehydrogenase
ASV54_RS02460	COG0083	homoserine kinase activity
ASV54_RS02480	COG3715	PTS system
ASV54_RS02485	COG3716	PTS system mannose fructose sorbose family IID component
ASV54_RS02495	COG3933	PFAM sigma-54 factor interaction domain-containing protein
ASV54_RS02495	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
ASV54_RS02500	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ASV54_RS02500	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
ASV54_RS02505	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
ASV54_RS02505	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ASV54_RS02510	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
ASV54_RS02520	COG0439	Biotin carboxylase
ASV54_RS02530	COG0825	malonyl-CoA metabolic process
ASV54_RS02535	COG1316	TRANSCRIPTIONal
ASV54_RS02545	COG0697	spore germination
ASV54_RS02550	COG0588	phosphoglycerate mutase activity
ASV54_RS02565	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
ASV54_RS02575	COG0756	dUTP diphosphatase activity
ASV54_RS02595	COG4956	integral membrane protein (PIN domain superfamily)
ASV54_RS02600	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
ASV54_RS02605	COG0215	cysteine-tRNA ligase activity
ASV54_RS02610	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
ASV54_RS02615	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ASV54_RS02630	COG0267	Belongs to the bacterial ribosomal protein bL33 family
ASV54_RS02640	COG0250	Participates in transcription elongation, termination and antitermination
ASV54_RS02650	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
ASV54_RS02655	COG0081	regulation of translation
ASV54_RS02660	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
ASV54_RS02665	COG0222	ribosome binding
ASV54_RS02690	COG1611	Belongs to the LOG family
ASV54_RS02700	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ASV54_RS02705	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
ASV54_RS02710	COG2813	Specifically methylates the guanine in position
ASV54_RS02725	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
ASV54_RS02730	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
ASV54_RS02735	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
ASV54_RS02745	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
ASV54_RS02750	COG3870	Protein conserved in bacteria
ASV54_RS02755	COG0470	DNA polymerase III
ASV54_RS02760	COG4467	Involved in initiation control of chromosome replication
ASV54_RS02775	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
ASV54_RS02790	COG3639	organic phosphonate transmembrane transporter activity
ASV54_RS02800	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
ASV54_RS02810	COG1214	PFAM Peptidase M22, glycoprotease
ASV54_RS02815	COG0456	acetyltransferase
ASV54_RS02820	COG0456	acetyltransferase
ASV54_RS02825	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
ASV54_RS02835	COG0488	(ABC) transporter
ASV54_RS02840	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
ASV54_RS02855	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
ASV54_RS02860	COG0459	protein refolding
ASV54_RS02865	COG0531	amino acid
ASV54_RS02870	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
ASV54_RS02875	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
ASV54_RS02880	COG1739	Uncharacterized protein family UPF0029
ASV54_RS02885	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
ASV54_RS02900	COG0653	protein targeting
ASV54_RS02915	COG0745	RESPONSE REGULATOR receiver
ASV54_RS02920	COG5002	protein histidine kinase activity
ASV54_RS02930	COG0573	inorganic phosphate transmembrane transporter activity
ASV54_RS02935	COG0581	inorganic phosphate transmembrane transporter activity
ASV54_RS02940	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
ASV54_RS02945	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
ASV54_RS02950	COG0704	Plays a role in the regulation of phosphate uptake
ASV54_RS02955	COG1983	PspC domain protein
ASV54_RS02960	COG1950	PFAM Membrane protein of
ASV54_RS02965	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
ASV54_RS02970	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
ASV54_RS02975	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
ASV54_RS02980	COG1210	Utp--glucose-1-phosphate uridylyltransferase
ASV54_RS02990	COG0446	pyridine nucleotide-disulphide oxidoreductase
ASV54_RS02995	COG0492	ferredoxin-NADP+ reductase activity
ASV54_RS03000	COG2323	membrane
ASV54_RS03010	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
ASV54_RS03020	COG0446	pyridine nucleotide-disulphide oxidoreductase
ASV54_RS03030	COG2814	Major facilitator Superfamily
ASV54_RS03040	COG0556	nucleotide-excision repair
ASV54_RS03045	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
ASV54_RS03050	COG1854	S-ribosylhomocysteine lyase activity
ASV54_RS03055	COG0137	argininosuccinate synthase activity
ASV54_RS03060	COG0165	Argininosuccinate lyase
ASV54_RS03070	COG1660	Displays ATPase and GTPase activities
ASV54_RS03080	COG1481	regulation of sporulation
ASV54_RS03090	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
ASV54_RS03095	COG0740	serine-type endopeptidase activity
ASV54_RS03105	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
ASV54_RS03110	COG2390	Transcriptional regulator
ASV54_RS03120	COG0126	phosphoglycerate kinase activity
ASV54_RS03125	COG0149	triose-phosphate isomerase activity
ASV54_RS03130	COG0148	phosphopyruvate hydratase activity
ASV54_RS03145	COG0038	chloride channel
ASV54_RS03150	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
ASV54_RS03160	COG0557	exoribonuclease II activity
ASV54_RS03165	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
ASV54_RS03175	COG0765	amino acid transport
ASV54_RS03180	COG1126	abc transporter atp-binding protein
ASV54_RS03190	COG0561	phosphatase activity
ASV54_RS03195	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
ASV54_RS03200	COG0280	phosphate acetyltransferase
ASV54_RS03205	COG0802	atpase or kinase
ASV54_RS03220	COG0708	Exodeoxyribonuclease III
ASV54_RS03230	COG0812	UDP-N-acetylmuramate dehydrogenase activity
ASV54_RS03235	COG0025	NhaP-type Na H and K H
ASV54_RS03260	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
ASV54_RS03265	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
ASV54_RS03275	COG0561	phosphatase activity
ASV54_RS03285	COG2017	converts alpha-aldose to the beta-anomer
ASV54_RS03300	COG0778	Nitroreductase
ASV54_RS03325	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
ASV54_RS03340	COG1393	Belongs to the ArsC family
ASV54_RS03355	COG0477	Major facilitator Superfamily
ASV54_RS03365	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
ASV54_RS03375	COG3475	LICD family
ASV54_RS03390	COG2252	PERMEase
ASV54_RS03395	COG0028	Belongs to the TPP enzyme family
ASV54_RS03400	COG0196	riboflavin kinase activity
ASV54_RS03405	COG0028	Belongs to the TPP enzyme family
ASV54_RS03410	COG2267	carboxylic ester hydrolase activity
ASV54_RS03420	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
ASV54_RS03420	COG2755	lipolytic protein G-D-S-L family
ASV54_RS03425	COG2936	dipeptidyl-peptidase activity
ASV54_RS03440	COG0531	amino acid
ASV54_RS03465	COG0194	GDP metabolic process
ASV54_RS03470	COG0735	belongs to the Fur family
ASV54_RS03485	COG0546	phosphoglycolate phosphatase activity
ASV54_RS03490	COG0436	Aminotransferase
ASV54_RS03495	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
ASV54_RS03515	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ASV54_RS03520	COG0765	amino acid transport
ASV54_RS03525	COG0765	amino acid transport
ASV54_RS03530	COG2190	(PTS) system
ASV54_RS03530	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ASV54_RS03530	COG1263	PTS System
ASV54_RS03540	COG1263	PTS System
ASV54_RS03540	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ASV54_RS03545	COG3394	polysaccharide catabolic process
ASV54_RS03550	COG0531	amino acid
ASV54_RS03560	COG1846	Transcriptional regulator
ASV54_RS03590	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
ASV54_RS03600	COG2076	Multidrug Resistance protein
ASV54_RS03615	COG0588	phosphoglycerate mutase activity
ASV54_RS03620	COG0475	glutathione-regulated potassium exporter activity
ASV54_RS03620	COG0569	domain protein
ASV54_RS03625	COG0456	acetyltransferase
ASV54_RS03625	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
ASV54_RS03630	COG0586	Pfam SNARE associated Golgi protein
ASV54_RS03635	COG3973	AAA domain
ASV54_RS03640	COG2070	2-Nitropropane dioxygenase
ASV54_RS03645	COG1072	(Pantothenic acid kinase))
ASV54_RS03650	COG0518	GMP synthase (glutamine-hydrolyzing) activity
ASV54_RS03650	COG0519	Catalyzes the synthesis of GMP from XMP
ASV54_RS03655	COG0464	growth
ASV54_RS03685	COG1396	sequence-specific DNA binding
ASV54_RS03690	COG1266	CAAX protease self-immunity
ASV54_RS03695	COG1733	regulation of RNA biosynthetic process
ASV54_RS03700	COG2814	Major facilitator Superfamily
ASV54_RS03715	COG2755	lipolytic protein G-D-S-L family
ASV54_RS03715	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
ASV54_RS03720	COG2261	transglycosylase associated protein
ASV54_RS03735	COG1302	Protein conserved in bacteria
ASV54_RS03765	COG0308	aminopeptidase N
ASV54_RS03795	COG0572	uridine kinase
ASV54_RS03810	COG0583	DNA-binding transcription factor activity
ASV54_RS03815	COG1053	succinate dehydrogenase
ASV54_RS03825	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
ASV54_RS03830	COG0017	Asparaginyl-tRNA synthetase
ASV54_RS03835	COG2502	aspartate--ammonia ligase
ASV54_RS03840	COG4690	dipeptidase activity
ASV54_RS03860	COG0514	ATP-dependent DNA helicase (RecQ)
ASV54_RS03865	COG0564	pseudouridine synthase activity
ASV54_RS03870	COG0640	Transcriptional regulator
ASV54_RS03920	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
ASV54_RS03925	COG0527	aspartate kinase activity
ASV54_RS03930	COG0367	asparagine synthase
ASV54_RS03980	COG2814	Major facilitator Superfamily
ASV54_RS04000	COG1278	Cold shock
ASV54_RS04005	COG2966	Psort location CytoplasmicMembrane, score
ASV54_RS04015	COG1316	TRANSCRIPTIONal
ASV54_RS04035	COG1959	2 iron, 2 sulfur cluster binding
ASV54_RS04040	COG0028	Belongs to the TPP enzyme family
ASV54_RS04045	COG0833	amino acid
ASV54_RS04055	COG1428	Deoxynucleoside kinase
ASV54_RS04060	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
ASV54_RS04100	COG4463	regulation of RNA biosynthetic process
ASV54_RS04105	COG0542	response to heat
ASV54_RS04115	COG0085	RNA polymerase activity
ASV54_RS04120	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
ASV54_RS04125	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
ASV54_RS04130	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
ASV54_RS04135	COG0049	tRNA binding
ASV54_RS04140	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
ASV54_RS04145	COG0051	transcription antitermination factor activity, RNA binding
ASV54_RS04150	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
ASV54_RS04155	COG0088	Forms part of the polypeptide exit tunnel
ASV54_RS04160	COG0089	rRNA binding
ASV54_RS04165	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
ASV54_RS04170	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
ASV54_RS04175	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
ASV54_RS04180	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
ASV54_RS04185	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
ASV54_RS04190	COG0255	Belongs to the universal ribosomal protein uL29 family
ASV54_RS04195	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
ASV54_RS04200	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
ASV54_RS04205	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
ASV54_RS04210	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
ASV54_RS04215	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
ASV54_RS04220	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
ASV54_RS04225	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
ASV54_RS04230	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
ASV54_RS04235	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
ASV54_RS04240	COG1841	ribosomal large subunit assembly
ASV54_RS04245	COG0200	Binds to the 23S rRNA
ASV54_RS04255	COG0563	adenylate kinase activity
ASV54_RS04260	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
ASV54_RS04265	COG0257	Belongs to the bacterial ribosomal protein bL36 family
ASV54_RS04270	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
ASV54_RS04275	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
ASV54_RS04280	COG0202	RNA polymerase activity
ASV54_RS04285	COG0203	ribosomal protein L17
ASV54_RS04310	COG4939	FMN-binding domain protein
ASV54_RS04320	COG1122	ATPase activity
ASV54_RS04325	COG1122	ATPase activity
ASV54_RS04335	COG0101	tRNA pseudouridine synthase activity
ASV54_RS04340	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
ASV54_RS04345	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
ASV54_RS04365	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
ASV54_RS04370	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
ASV54_RS04375	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
ASV54_RS04380	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
ASV54_RS04385	COG0471	metal ion transport
ASV54_RS04390	COG2151	metal-sulfur cluster biosynthetic enzyme
ASV54_RS04395	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
ASV54_RS04405	COG1917	Cupin 2, conserved barrel domain protein
ASV54_RS04405	COG4977	sequence-specific DNA binding
ASV54_RS04410	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
ASV54_RS04415	COG1121	(ABC) transporter
ASV54_RS04420	COG1108	ABC-type Mn2 Zn2 transport systems permease components
ASV54_RS04425	COG0803	Belongs to the bacterial solute-binding protein 9 family
ASV54_RS04435	COG0039	L-malate dehydrogenase activity
ASV54_RS04440	COG0471	metal ion transport
ASV54_RS04460	COG3052	prosthetic group binding
ASV54_RS04500	COG0114	fumarate hydratase activity
ASV54_RS04505	COG1053	succinate dehydrogenase
ASV54_RS04515	COG0583	DNA-binding transcription factor activity
ASV54_RS04520	COG0583	DNA-binding transcription factor activity
ASV54_RS04525	COG0281	malic enzyme
ASV54_RS04535	COG0531	amino acid
ASV54_RS04540	COG4684	Psort location CytoplasmicMembrane, score
ASV54_RS04555	COG1271	oxidase subunit
ASV54_RS04560	COG1294	oxidase, subunit
ASV54_RS04565	COG4988	ABC transporter
ASV54_RS04570	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
ASV54_RS04585	COG0142	geranyltranstransferase activity
ASV54_RS04600	COG1705	Flagellar rod assembly protein muramidase FlgJ
ASV54_RS04605	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
ASV54_RS04610	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
ASV54_RS04615	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
ASV54_RS04625	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
ASV54_RS04630	COG4851	CamS sex pheromone cAM373 precursor
ASV54_RS04635	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
ASV54_RS04640	COG0154	amidase activity
ASV54_RS04645	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
ASV54_RS04650	COG1597	lipid kinase activity
ASV54_RS04655	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
ASV54_RS04670	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
ASV54_RS04680	COG1737	Transcriptional regulator
ASV54_RS04695	COG1278	Cold shock
ASV54_RS04700	COG0673	inositol 2-dehydrogenase activity
ASV54_RS04705	COG0513	Belongs to the DEAD box helicase family
ASV54_RS04720	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
ASV54_RS04745	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
ASV54_RS04755	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
ASV54_RS04765	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
ASV54_RS04770	COG0562	UDP-galactopyranose mutase
ASV54_RS04800	COG1442	glycosyl transferase family 8
ASV54_RS04800	COG1216	Glycosyl transferase, family 2
ASV54_RS04820	COG2244	polysaccharide biosynthetic process
ASV54_RS04855	COG2207	Transcriptional regulator
ASV54_RS04855	COG1609	Transcriptional regulator
ASV54_RS04875	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
ASV54_RS04910	COG2137	regulation of response to DNA damage stimulus
ASV54_RS04915	COG3557	Belongs to the UPF0374 family
ASV54_RS04935	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
ASV54_RS04945	COG0628	permease
ASV54_RS04950	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
ASV54_RS04955	COG2610	gluconate transmembrane transporter activity
ASV54_RS04960	COG1070	Carbohydrate kinase
ASV54_RS04965	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
ASV54_RS04970	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ASV54_RS04975	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
ASV54_RS05005	COG4166	transmembrane transport
ASV54_RS05010	COG0601	transmembrane transport
ASV54_RS05015	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ASV54_RS05020	COG0444	Belongs to the ABC transporter superfamily
ASV54_RS05025	COG4608	Belongs to the ABC transporter superfamily
ASV54_RS05035	COG0582	viral genome integration into host DNA
ASV54_RS05040	COG0542	response to heat
ASV54_RS05060	COG0438	transferase activity, transferring glycosyl groups
ASV54_RS05065	COG0438	transferase activity, transferring glycosyl groups
ASV54_RS05075	COG1686	Belongs to the peptidase S11 family
ASV54_RS05080	COG0436	Aminotransferase
ASV54_RS05085	COG4703	Protein of unknown function (DUF1797)
ASV54_RS05090	COG1368	sulfuric ester hydrolase activity
ASV54_RS05180	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
ASV54_RS05200	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
ASV54_RS05215	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
ASV54_RS05220	COG0833	amino acid
ASV54_RS05225	COG2040	homocysteine
ASV54_RS05230	COG0438	transferase activity, transferring glycosyl groups
ASV54_RS05240	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
ASV54_RS05245	COG0477	Major facilitator Superfamily
ASV54_RS05260	COG0438	transferase activity, transferring glycosyl groups
ASV54_RS05275	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
ASV54_RS05285	COG0495	leucyl-tRNA aminoacylation
ASV54_RS05290	COG2244	polysaccharide biosynthetic process
ASV54_RS05295	COG1187	pseudouridine synthase activity
ASV54_RS05300	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
ASV54_RS05305	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
ASV54_RS05315	COG3842	ATPase activity
ASV54_RS05320	COG1175	transmembrane transport
ASV54_RS05325	COG0395	ABC-type sugar transport system, permease component
ASV54_RS05340	COG1428	Deoxynucleoside kinase
ASV54_RS05345	COG1970	mechanosensitive ion channel activity
ASV54_RS05350	COG1511	domain protein
ASV54_RS05350	COG1511	domain protein
ASV54_RS05380	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
ASV54_RS05385	COG0789	Transcriptional regulator
ASV54_RS05395	COG0697	spore germination
ASV54_RS05400	COG0561	phosphatase activity
ASV54_RS05420	COG3279	Response regulator of the LytR AlgR family
ASV54_RS05440	COG1846	Transcriptional regulator
ASV54_RS05455	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
ASV54_RS05495	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
ASV54_RS05550	COG0629	single-stranded DNA binding
ASV54_RS05765	COG0646	methionine synthase
ASV54_RS05765	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
ASV54_RS05770	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
ASV54_RS05780	COG2046	Belongs to the sulfate adenylyltransferase family
ASV54_RS05785	COG0529	Catalyzes the synthesis of activated sulfate
ASV54_RS05790	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
ASV54_RS05800	COG0471	metal ion transport
ASV54_RS05800	COG3273	potassium ion transport
ASV54_RS05805	COG0534	Mate efflux family protein
ASV54_RS05825	COG2153	protein acetylation
ASV54_RS05830	COG0018	arginyl-trna synthetase
ASV54_RS05840	COG1136	(ABC) transporter
ASV54_RS05840	COG0577	efflux transmembrane transporter activity
ASV54_RS05860	COG1447	Phosphotransferase system cellobiose-specific component IIA
ASV54_RS05865	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
ASV54_RS05870	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
ASV54_RS05875	COG2723	6-phospho-beta-galactosidase activity
ASV54_RS05885	COG1376	ErfK ybiS ycfS ynhG family protein
ASV54_RS05890	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
ASV54_RS05895	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ASV54_RS05905	COG0436	Aminotransferase
ASV54_RS05910	COG1438	arginine binding
ASV54_RS05920	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
ASV54_RS05925	COG3679	Belongs to the UPF0342 family
ASV54_RS05930	COG0420	3'-5' exonuclease activity
ASV54_RS05935	COG4717	serine-type aminopeptidase activity
ASV54_RS05940	COG3481	metal-dependent phosphohydrolase, HD sub domain
ASV54_RS05955	COG0583	DNA-binding transcription factor activity
ASV54_RS05965	COG3976	FMN-binding domain protein
ASV54_RS05965	COG1053	succinate dehydrogenase
ASV54_RS05965	COG0431	NADPH-dependent FMN reductase
ASV54_RS06000	COG2217	Heavy metal translocating P-type atpase
ASV54_RS06005	COG0148	phosphopyruvate hydratase activity
ASV54_RS06015	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
ASV54_RS06025	COG0463	Glycosyl transferase, family 2
ASV54_RS06045	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ASV54_RS06045	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ASV54_RS06050	COG0307	riboflavin synthase, alpha
ASV54_RS06055	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
ASV54_RS06055	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
ASV54_RS06060	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
ASV54_RS06075	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
ASV54_RS06085	COG0446	pyridine nucleotide-disulphide oxidoreductase
ASV54_RS06115	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
ASV54_RS06125	COG0537	adenosine 5'-monophosphoramidase activity
ASV54_RS06130	COG1131	(ABC) transporter
ASV54_RS06135	COG4473	ABC transporter
ASV54_RS06140	COG0510	thiamine kinase activity
ASV54_RS06145	COG0220	tRNA (guanine-N7-)-methyltransferase activity
ASV54_RS06155	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ASV54_RS06160	COG1674	ftsk spoiiie
ASV54_RS06165	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
ASV54_RS06190	COG0719	Fe-S assembly protein
ASV54_RS06195	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
ASV54_RS06205	COG0719	Fe-S assembly protein
ASV54_RS06210	COG2151	metal-sulfur cluster biosynthetic enzyme
ASV54_RS06225	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
ASV54_RS06225	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
ASV54_RS06230	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
ASV54_RS06235	COG0237	dephospho-CoA kinase activity
ASV54_RS06240	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
ASV54_RS06245	COG3611	Membrane attachment protein
ASV54_RS06250	COG1484	DNA-dependent DNA replication
ASV54_RS06255	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
ASV54_RS06260	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
ASV54_RS06265	COG0291	Belongs to the bacterial ribosomal protein bL35 family
ASV54_RS06270	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
ASV54_RS06280	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
ASV54_RS06285	COG0604	alcohol dehydrogenase
ASV54_RS06290	COG1733	regulation of RNA biosynthetic process
ASV54_RS06300	COG1215	transferase activity, transferring glycosyl groups
ASV54_RS06315	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
ASV54_RS06320	COG1534	Rna-binding protein
ASV54_RS06325	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
ASV54_RS06330	COG1713	HD superfamily hydrolase involved in NAD metabolism
ASV54_RS06335	COG0799	negative regulation of ribosome biogenesis
ASV54_RS06340	COG2226	methyltransferase
ASV54_RS06345	COG1323	Belongs to the UPF0348 family
ASV54_RS06355	COG0333	Belongs to the bacterial ribosomal protein bL32 family
ASV54_RS06370	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
ASV54_RS06375	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
ASV54_RS06380	COG0745	RESPONSE REGULATOR receiver
ASV54_RS06385	COG5002	protein histidine kinase activity
ASV54_RS06400	COG0419	ATPase involved in DNA repair
ASV54_RS06405	COG0420	3'-5' exonuclease activity
ASV54_RS06415	COG0706	membrane insertase activity
ASV54_RS06420	COG1254	Belongs to the acylphosphatase family
ASV54_RS06425	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ASV54_RS06435	COG1733	regulation of RNA biosynthetic process
ASV54_RS06440	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
ASV54_RS06445	COG0072	phenylalanine-tRNA ligase activity
ASV54_RS06445	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ASV54_RS06450	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
ASV54_RS06455	COG0572	uridine kinase
ASV54_RS06460	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
ASV54_RS06485	COG4841	protein insertion into membrane
ASV54_RS06495	COG0768	penicillin binding
ASV54_RS06500	COG0267	Belongs to the bacterial ribosomal protein bL33 family
ASV54_RS06505	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
ASV54_RS06510	COG0705	Rhomboid family
ASV54_RS06510	COG0457	Tetratricopeptide repeat
ASV54_RS06520	COG1940	carbohydrate kinase activity
ASV54_RS06540	COG0584	glycerophosphoryl diester phosphodiesterase
ASV54_RS06545	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
ASV54_RS06550	COG0789	Transcriptional regulator
ASV54_RS06605	COG0261	This protein binds to 23S rRNA in the presence of protein L20
ASV54_RS06615	COG0211	Belongs to the bacterial ribosomal protein bL27 family
ASV54_RS06620	COG0006	proline dipeptidase activity
ASV54_RS06625	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
ASV54_RS06630	COG1302	Protein conserved in bacteria
ASV54_RS06635	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
ASV54_RS06640	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
ASV54_RS06645	COG1570	exodeoxyribonuclease VII activity
ASV54_RS06650	COG1722	exodeoxyribonuclease VII activity
ASV54_RS06655	COG0142	geranyltranstransferase activity
ASV54_RS06660	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
ASV54_RS06665	COG1438	arginine binding
ASV54_RS06670	COG0497	DNA recombination
ASV54_RS06685	COG1732	Glycine betaine
ASV54_RS06700	COG0194	GDP metabolic process
ASV54_RS06705	COG1758	RNA polymerase activity
ASV54_RS06710	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
ASV54_RS06715	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
ASV54_RS06720	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
ASV54_RS06725	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
ASV54_RS06725	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
ASV54_RS06730	COG0631	protein serine/threonine phosphatase activity
ASV54_RS06735	COG0515	serine threonine protein kinase
ASV54_RS06735	COG2815	serine threonine protein kinase
ASV54_RS06740	COG1162	GTPase activity
ASV54_RS06745	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
ASV54_RS06750	COG1564	THIamine pyrophosphokinase
ASV54_RS06760	COG0227	Belongs to the bacterial ribosomal protein bL28 family
ASV54_RS06765	COG1302	Protein conserved in bacteria
ASV54_RS06770	COG1461	Dihydroxyacetone kinase
ASV54_RS06775	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
ASV54_RS06780	COG0416	fatty acid biosynthetic process
ASV54_RS06785	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
ASV54_RS06790	COG0571	ribonuclease III activity
ASV54_RS06795	COG1196	nuclear chromosome segregation
ASV54_RS06800	COG0552	protein localization to endoplasmic reticulum
ASV54_RS06805	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
ASV54_RS06810	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
ASV54_RS06815	COG0228	four-way junction DNA binding
ASV54_RS06820	COG1837	Belongs to the UPF0109 family
ASV54_RS06825	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
ASV54_RS06830	COG0336	Belongs to the RNA methyltransferase TrmD family
ASV54_RS06835	COG0335	large ribosomal subunit rRNA binding
ASV54_RS06855	COG1131	(ABC) transporter
ASV54_RS06870	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
ASV54_RS06870	COG0512	Glutamine amidotransferase of anthranilate synthase
ASV54_RS06875	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
ASV54_RS06880	COG0134	indole-3-glycerol-phosphate synthase activity
ASV54_RS06885	COG0135	phosphoribosylanthranilate isomerase activity
ASV54_RS06890	COG0133	tryptophan synthase activity
ASV54_RS06895	COG0159	tryptophan synthase activity
ASV54_RS06915	COG1063	alcohol dehydrogenase
ASV54_RS06925	COG0300	oxidoreductase activity
ASV54_RS06935	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
ASV54_RS06940	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
ASV54_RS06945	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
ASV54_RS06950	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
ASV54_RS06955	COG1028	Short-chain dehydrogenase reductase Sdr
ASV54_RS06960	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
ASV54_RS06975	COG0439	Biotin carboxylase
ASV54_RS06990	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
ASV54_RS07000	COG1811	Na channel or pump
ASV54_RS07005	COG0583	DNA-binding transcription factor activity
ASV54_RS07010	COG1607	acyl-coa hydrolase
ASV54_RS07015	COG1162	GTPase activity
ASV54_RS07025	COG0477	Major facilitator Superfamily
ASV54_RS07045	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
ASV54_RS07050	COG3397	chitin binding
ASV54_RS07065	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
ASV54_RS07075	COG3152	Membrane
ASV54_RS07080	COG1597	lipid kinase activity
ASV54_RS07095	COG2261	transglycosylase associated protein
ASV54_RS07100	COG3237	CsbD-like
ASV54_RS07115	COG1942	4-Oxalocrotonate Tautomerase
ASV54_RS07155	COG0531	amino acid
ASV54_RS07160	COG0561	phosphatase activity
ASV54_RS07165	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
ASV54_RS07165	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
ASV54_RS07185	COG2017	converts alpha-aldose to the beta-anomer
ASV54_RS07190	COG1304	FMN binding
ASV54_RS07215	COG1199	ATP-dependent helicase activity
ASV54_RS07215	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
ASV54_RS07230	COG0017	Asparaginyl-tRNA synthetase
ASV54_RS07245	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
ASV54_RS07250	COG2011	ABC-type metal ion transport system permease component
ASV54_RS07255	COG1464	Belongs to the NlpA lipoprotein family
ASV54_RS07265	COG1177	transmembrane transport
ASV54_RS07270	COG1840	ABC-type Fe3 transport system, periplasmic component
ASV54_RS07290	COG3331	DNA recombination
ASV54_RS07295	COG4474	Belongs to the UPF0398 family
ASV54_RS07300	COG3599	regulation of cell shape
ASV54_RS07310	COG0116	Belongs to the methyltransferase superfamily
ASV54_RS07325	COG0477	Major facilitator Superfamily
ASV54_RS07330	COG1073	alpha beta
ASV54_RS07340	COG1216	Glycosyl transferase, family 2
ASV54_RS07360	COG1619	proteins homologs of microcin C7 resistance protein MccF
ASV54_RS07385	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ASV54_RS07400	COG2759	Belongs to the formate--tetrahydrofolate ligase family
ASV54_RS07405	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
ASV54_RS07410	COG0564	pseudouridine synthase activity
ASV54_RS07415	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
ASV54_RS07420	COG0505	Belongs to the CarA family
ASV54_RS07425	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
ASV54_RS07435	COG5646	InterPro IPR014922
ASV54_RS07460	COG1131	(ABC) transporter
ASV54_RS07465	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
ASV54_RS07470	COG1293	RNA-binding protein homologous to eukaryotic snRNP
ASV54_RS07480	COG1307	EDD domain protein, DegV family
ASV54_RS07540	COG1113	amino acid transport
ASV54_RS07555	COG1620	l-lactate permease
ASV54_RS07565	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
ASV54_RS07575	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
ASV54_RS07590	COG1846	Transcriptional regulator
ASV54_RS07595	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ASV54_RS07630	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
ASV54_RS07635	COG1227	inorganic diphosphatase activity
ASV54_RS07640	COG0583	DNA-binding transcription factor activity
ASV54_RS07650	COG0187	DNA topoisomerase II activity
ASV54_RS07655	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
ASV54_RS07665	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
ASV54_RS07670	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
ASV54_RS07675	COG4974	Belongs to the 'phage' integrase family
ASV54_RS07680	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
ASV54_RS07685	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
ASV54_RS07690	COG0758	DNA mediated transformation
ASV54_RS07695	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
ASV54_RS07700	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
ASV54_RS07710	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
ASV54_RS07715	COG0583	DNA-binding transcription factor activity
ASV54_RS07735	COG2814	Major facilitator Superfamily
ASV54_RS07740	COG3409	Peptidoglycan-binding domain 1 protein
ASV54_RS07740	COG0793	Belongs to the peptidase S41A family
ASV54_RS07745	COG4479	Belongs to the UPF0346 family
ASV54_RS07750	COG4698	Protein conserved in bacteria
ASV54_RS07755	COG2755	lipolytic protein G-D-S-L family
ASV54_RS07760	COG1307	EDD domain protein, DegV family
ASV54_RS07765	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
ASV54_RS07770	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
ASV54_RS07775	COG0488	(ABC) transporter
ASV54_RS07785	COG0617	tRNA 3'-terminal CCA addition
ASV54_RS07790	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
ASV54_RS07795	COG0561	phosphatase activity
ASV54_RS07800	COG0457	Tetratricopeptide repeat
ASV54_RS07815	COG1160	GTP binding
ASV54_RS07820	COG0539	negative regulation of cytoplasmic translation
ASV54_RS07825	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
ASV54_RS07835	COG0514	ATP-dependent DNA helicase (RecQ)
ASV54_RS07845	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
ASV54_RS07850	COG1187	pseudouridine synthase activity
ASV54_RS07855	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
ASV54_RS07860	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
ASV54_RS07870	COG4974	Belongs to the 'phage' integrase family
ASV54_RS07875	COG2996	Protein conserved in bacteria
ASV54_RS07895	COG0205	6-phosphofructokinase activity
ASV54_RS07900	COG0587	DNA-directed DNA polymerase activity
ASV54_RS07910	COG0542	response to heat
ASV54_RS07920	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
ASV54_RS07925	COG2384	SAM-dependent methyltransferase
ASV54_RS07950	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
ASV54_RS07950	COG0574	Belongs to the PEP-utilizing enzyme family
ASV54_RS07960	COG1846	Transcriptional regulator
ASV54_RS07980	COG2217	Heavy metal translocating P-type atpase
ASV54_RS07985	COG0148	phosphopyruvate hydratase activity
ASV54_RS07990	COG0477	Major facilitator Superfamily
ASV54_RS08000	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
ASV54_RS08005	COG0446	pyridine nucleotide-disulphide oxidoreductase
ASV54_RS08010	COG1349	DNA-binding transcription factor activity
ASV54_RS08020	COG1393	Belongs to the ArsC family
ASV54_RS08040	COG0546	phosphoglycolate phosphatase activity
ASV54_RS08070	COG0583	DNA-binding transcription factor activity
ASV54_RS08075	COG0604	alcohol dehydrogenase
ASV54_RS08085	COG0446	pyridine nucleotide-disulphide oxidoreductase
ASV54_RS08090	COG2197	response regulator
ASV54_RS08095	COG4585	Histidine kinase
ASV54_RS08105	COG1131	(ABC) transporter
ASV54_RS08115	COG0519	Catalyzes the synthesis of GMP from XMP
ASV54_RS08130	COG1131	(ABC) transporter
ASV54_RS08150	COG1131	(ABC) transporter
ASV54_RS08155	COG1725	Transcriptional regulator
ASV54_RS08165	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
ASV54_RS08170	COG0358	DNA primase activity
ASV54_RS08175	COG0751	glycine-tRNA ligase activity
ASV54_RS08180	COG0752	glycyl-tRNA synthetase alpha subunit
ASV54_RS08185	COG1381	Involved in DNA repair and RecF pathway recombination
ASV54_RS08190	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
ASV54_RS08195	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
ASV54_RS08200	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
ASV54_RS08205	COG1702	phosphate starvation-inducible protein PhoH
ASV54_RS08215	COG1610	YqeY-like protein
ASV54_RS08220	COG0828	Belongs to the bacterial ribosomal protein bS21 family
ASV54_RS08225	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
ASV54_RS08235	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
ASV54_RS08245	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
ASV54_RS08255	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
ASV54_RS08260	COG0124	histidyl-tRNA synthetase
ASV54_RS08265	COG4991	sh3 domain protein
ASV54_RS08265	COG3103	Sh3 type 3 domain protein
ASV54_RS08265	COG0860	N-Acetylmuramoyl-L-alanine amidase
ASV54_RS08270	COG3001	Fructosamine kinase
ASV54_RS08275	COG0546	phosphoglycolate phosphatase activity
ASV54_RS08280	COG1490	D-aminoacyl-tRNA deacylase activity
ASV54_RS08285	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
ASV54_RS08295	COG1385	rRNA (uridine-N3-)-methyltransferase activity
ASV54_RS08300	COG2264	protein methyltransferase activity
ASV54_RS08305	COG2094	Belongs to the DNA glycosylase MPG family
ASV54_RS08330	COG0582	viral genome integration into host DNA
ASV54_RS08335	COG0481	GTPase activity
ASV54_RS08340	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
ASV54_RS08345	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
ASV54_RS08350	COG1696	Membrane protein involved in D-alanine export
ASV54_RS08355	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
ASV54_RS08365	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
ASV54_RS08370	COG0484	heat shock protein binding
ASV54_RS08375	COG0443	Heat shock 70 kDa protein
ASV54_RS08380	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
ASV54_RS08385	COG1420	regulation of RNA biosynthetic process
ASV54_RS08390	COG3527	Alpha-acetolactate decarboxylase
ASV54_RS08395	COG0196	riboflavin kinase activity
ASV54_RS08400	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
ASV54_RS08405	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
ASV54_RS08410	COG0287	Prephenate dehydrogenase
ASV54_RS08415	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
ASV54_RS08425	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
ASV54_RS08430	COG0738	Major facilitator superfamily
ASV54_RS08435	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
ASV54_RS08440	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
ASV54_RS08450	COG2740	Nucleic-acid-binding protein implicated in transcription termination
ASV54_RS08455	COG0195	Participates in both transcription termination and antitermination
ASV54_RS08460	COG0779	Required for maturation of 30S ribosomal subunits
ASV54_RS08465	COG2176	DNA-directed DNA polymerase activity
ASV54_RS08470	COG0442	prolyl-tRNA aminoacylation
ASV54_RS08475	COG0750	zinc metalloprotease
ASV54_RS08480	COG4589	Belongs to the CDS family
ASV54_RS08485	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
ASV54_RS08490	COG0233	cytoplasmic translational termination
ASV54_RS08495	COG0528	UMP kinase activity
ASV54_RS08500	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
ASV54_RS08505	COG0052	Belongs to the universal ribosomal protein uS2 family
ASV54_RS08515	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
ASV54_RS08520	COG2827	Endonuclease containing a URI domain
ASV54_RS08525	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
ASV54_RS08530	COG0204	Acyl-transferase
ASV54_RS08535	COG3763	UPF0154 protein
ASV54_RS08540	COG4224	UPF0291 protein
ASV54_RS08545	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
ASV54_RS08560	COG3425	synthase
ASV54_RS08575	COG0463	Glycosyl transferase, family 2
ASV54_RS08645	COG0393	Putative heavy-metal-binding
ASV54_RS08660	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
ASV54_RS08665	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
ASV54_RS08665	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
ASV54_RS08670	COG5416	Lipopolysaccharide assembly protein A domain
ASV54_RS08675	COG0300	oxidoreductase activity
ASV54_RS08680	COG1234	tRNA 3'-trailer cleavage
ASV54_RS08690	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
ASV54_RS08695	COG1349	DNA-binding transcription factor activity
ASV54_RS08700	COG1105	Belongs to the carbohydrate kinase PfkB family
ASV54_RS08705	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ASV54_RS08705	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ASV54_RS08705	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
ASV54_RS08710	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
ASV54_RS08735	COG0297	glycogen (starch) synthase activity
ASV54_RS08740	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
ASV54_RS08745	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ASV54_RS08755	COG0489	protein tyrosine kinase activity
ASV54_RS08765	COG0322	excinuclease ABC activity
ASV54_RS08770	COG1126	abc transporter atp-binding protein
ASV54_RS08775	COG0765	amino acid transport
ASV54_RS08795	COG0218	Necessary for normal cell division and for the maintenance of normal septation
ASV54_RS08800	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
ASV54_RS08805	COG0544	peptidyl-prolyl cis-trans isomerase activity
ASV54_RS08810	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
ASV54_RS08835	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
ASV54_RS08840	COG0268	Binds directly to 16S ribosomal RNA
ASV54_RS08850	COG1466	dna polymerase III delta subunit
ASV54_RS08855	COG2333	competence protein COMEC
ASV54_RS08855	COG0658	competence protein
ASV54_RS08860	COG2131	deaminase
ASV54_RS08865	COG1596	polysaccharide export
ASV54_RS08865	COG1555	photosystem II stabilization
ASV54_RS08870	COG3480	Lon protease (S16) C-terminal proteolytic domain
ASV54_RS08875	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
ASV54_RS08880	COG0742	ribosomal rna small subunit methyltransferase
ASV54_RS08885	COG4471	UPF0298 protein
ASV54_RS08890	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
ASV54_RS08895	COG0772	Belongs to the SEDS family
ASV54_RS08945	COG1217	gtp-binding protein TYPA
ASV54_RS08950	COG0483	inositol monophosphate 1-phosphatase activity
ASV54_RS08955	COG4476	Belongs to the UPF0223 family
ASV54_RS08960	COG0039	L-malate dehydrogenase activity
ASV54_RS08985	COG0242	peptide deformylase activity
ASV54_RS08995	COG5503	Protein of unknown function (DUF1447)
ASV54_RS09000	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
ASV54_RS09005	COG1597	lipid kinase activity
ASV54_RS09015	COG1388	LysM domain
ASV54_RS09015	COG3584	3D domain protein
ASV54_RS09025	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
ASV54_RS09030	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
ASV54_RS09070	COG0569	domain protein
ASV54_RS09075	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
ASV54_RS09080	COG0482	sulfurtransferase activity
ASV54_RS09090	COG1104	cysteine desulfurase activity
ASV54_RS09095	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
ASV54_RS09105	COG0494	nUDIX hydrolase
ASV54_RS09110	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
ASV54_RS09115	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
ASV54_RS09120	COG3599	regulation of cell shape
ASV54_RS09130	COG0762	integral membrane protein
ASV54_RS09135	COG1799	cell septum assembly
ASV54_RS09150	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
ASV54_RS09155	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
ASV54_RS09160	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
ASV54_RS09165	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
ASV54_RS09170	COG0768	penicillin binding
ASV54_RS09180	COG0275	rRNA processing
ASV54_RS09185	COG2001	Belongs to the MraZ family
ASV54_RS09205	COG1674	ftsk spoiiie
ASV54_RS09210	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
ASV54_RS09220	COG1114	Component of the transport system for branched-chain amino acids
ASV54_RS09240	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
ASV54_RS09245	COG0628	permease
ASV54_RS09255	COG2706	6-phosphogluconolactonase activity
ASV54_RS09260	COG3142	Participates in the control of copper homeostasis
ASV54_RS09265	COG0564	pseudouridine synthase activity
ASV54_RS09270	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
ASV54_RS09275	COG2357	RelA SpoT domain protein
ASV54_RS09285	COG1164	Oligoendopeptidase f
ASV54_RS09295	COG4862	establishment of competence for transformation
ASV54_RS09300	COG1393	Belongs to the ArsC family
ASV54_RS09305	COG1234	tRNA 3'-trailer cleavage
ASV54_RS09445	COG1098	S1 RNA binding domain
ASV54_RS09455	COG0586	Pfam SNARE associated Golgi protein
ASV54_RS09465	COG0647	UMP catabolic process
ASV54_RS09470	COG4470	Protein conserved in bacteria
ASV54_RS09475	COG0737	Belongs to the 5'-nucleotidase family
ASV54_RS09490	COG1113	amino acid transport
ASV54_RS09495	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
ASV54_RS09500	COG0827	DNA restriction-modification system
ASV54_RS09530	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
ASV54_RS09540	COG0217	transcriptional regulatory protein
ASV54_RS09555	COG1609	Transcriptional regulator
ASV54_RS09560	COG0006	proline dipeptidase activity
ASV54_RS09565	COG0789	Transcriptional regulator
ASV54_RS09580	COG0668	transmembrane transport
ASV54_RS09585	COG1473	amidohydrolase
ASV54_RS09590	COG2171	N-acyltransferase activity
ASV54_RS09595	COG0517	IMP dehydrogenase activity
ASV54_RS09605	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
ASV54_RS09610	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
ASV54_RS09615	COG1719	4-vinyl reductase, 4VR
ASV54_RS09620	COG3118	belongs to the thioredoxin family
ASV54_RS09625	COG1193	negative regulation of DNA recombination
ASV54_RS09635	COG3906	Belongs to the UPF0473 family
ASV54_RS09640	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
ASV54_RS09645	COG4472	Bacterial protein of unknown function (DUF965)
ASV54_RS09650	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
ASV54_RS09655	COG0513	Belongs to the DEAD box helicase family
ASV54_RS09660	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
ASV54_RS09665	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
ASV54_RS09670	COG1862	Preprotein translocase
ASV54_RS09675	COG0343	queuine tRNA-ribosyltransferase activity
ASV54_RS09680	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
ASV54_RS09685	COG2255	four-way junction helicase activity
ASV54_RS09690	COG0632	four-way junction helicase activity
ASV54_RS09725	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
ASV54_RS09730	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
ASV54_RS09735	COG1692	metallophosphoesterase
ASV54_RS09740	COG1418	mRNA catabolic process
ASV54_RS09745	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
ASV54_RS09750	COG1546	Belongs to the CinA family
ASV54_RS09750	COG1058	Belongs to the CinA family
ASV54_RS09755	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
ASV54_RS09760	COG1426	Protein conserved in bacteria
ASV54_RS09765	COG0612	Peptidase, M16
ASV54_RS09770	COG0612	Peptidase, M16
ASV54_RS09775	COG0527	aspartate kinase activity
ASV54_RS09785	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ASV54_RS09790	COG1126	abc transporter atp-binding protein
ASV54_RS09795	COG0765	amino acid transport
ASV54_RS09800	COG2894	cell division
ASV54_RS09805	COG0850	regulation of cytokinetic process
ASV54_RS09815	COG1792	Involved in formation and maintenance of cell shape
ASV54_RS09820	COG1077	Cell shape determining protein MreB Mrl
ASV54_RS09825	COG2003	Belongs to the UPF0758 family
ASV54_RS09830	COG0285	dihydrofolate synthase activity
ASV54_RS09835	COG0525	valine-tRNA ligase activity
ASV54_RS09845	COG1181	Belongs to the D-alanine--D-alanine ligase family
ASV54_RS09845	COG2918	glutathione biosynthetic process
ASV54_RS09850	COG0301	tRNA thio-modification
ASV54_RS09855	COG1104	cysteine desulfurase activity
ASV54_RS09865	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
ASV54_RS09870	COG1956	GAF domain-containing protein
ASV54_RS09875	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
ASV54_RS09880	COG4493	Belongs to the UPF0637 family
ASV54_RS09895	COG0640	Transcriptional regulator
ASV54_RS09900	COG0366	Alpha amylase catalytic
ASV54_RS09910	COG3716	PTS system mannose fructose sorbose family IID component
ASV54_RS09915	COG3715	PTS system
ASV54_RS09920	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ASV54_RS09925	COG1609	Transcriptional regulator
ASV54_RS09930	COG2918	glutathione biosynthetic process
ASV54_RS09930	COG0189	ligase activity
ASV54_RS09935	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
ASV54_RS09950	COG0589	response to stress
ASV54_RS09970	COG1181	Belongs to the D-alanine--D-alanine ligase family
ASV54_RS09990	COG1464	Belongs to the NlpA lipoprotein family
ASV54_RS09995	COG2011	ABC-type metal ion transport system permease component
ASV54_RS10000	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
ASV54_RS10005	COG0509	glycine decarboxylation via glycine cleavage system
ASV54_RS10010	COG0772	Belongs to the SEDS family
ASV54_RS10020	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
ASV54_RS10025	COG1077	Cell shape determining protein MreB Mrl
ASV54_RS10035	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
ASV54_RS10040	COG0355	proton-transporting ATP synthase activity, rotational mechanism
ASV54_RS10045	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
ASV54_RS10050	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
ASV54_RS10055	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
ASV54_RS10060	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
ASV54_RS10065	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
ASV54_RS10070	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
ASV54_RS10075	COG0356	it plays a direct role in the translocation of protons across the membrane
ASV54_RS10080	COG2233	PERMEase
ASV54_RS10095	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
ASV54_RS10100	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
ASV54_RS10105	COG0009	L-threonylcarbamoyladenylate synthase
ASV54_RS10110	COG2890	protein-(glutamine-N5) methyltransferase activity
ASV54_RS10115	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
ASV54_RS10120	COG1435	thymidine kinase activity
ASV54_RS10125	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
ASV54_RS10130	COG3442	glutamine amidotransferase
ASV54_RS10135	COG1482	cell wall glycoprotein biosynthetic process
ASV54_RS10140	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
ASV54_RS10150	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
ASV54_RS10165	COG1132	(ABC) transporter
ASV54_RS10180	COG0726	polysaccharide deacetylase
ASV54_RS10300	COG2868	ribosomal protein
ASV54_RS10425	COG1396	sequence-specific DNA binding
ASV54_RS10455	COG1970	mechanosensitive ion channel activity
ASV54_RS10465	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
ASV54_RS10535	COG4886	Leucine-rich repeat (LRR) protein
ASV54_RS10535	COG4932	domain protein
ASV54_RS10580	COG1132	(ABC) transporter
ASV54_RS10590	COG1136	(ABC) transporter
ASV54_RS10590	COG0577	efflux transmembrane transporter activity
ASV54_RS10600	COG0166	Belongs to the GPI family
ASV54_RS10605	COG4975	Glucose uptake
ASV54_RS10610	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
ASV54_RS10615	COG3850	Histidine kinase
ASV54_RS10615	COG5002	protein histidine kinase activity
ASV54_RS10620	COG0745	RESPONSE REGULATOR receiver
ASV54_RS10625	COG2848	UPF0210 protein
ASV54_RS10630	COG3830	Belongs to the UPF0237 family
ASV54_RS10655	COG0477	Major facilitator Superfamily
ASV54_RS10675	COG0791	NLP P60 protein
ASV54_RS10680	COG1522	sequence-specific DNA binding
ASV54_RS10700	COG0488	(ABC) transporter
ASV54_RS10730	COG1263	PTS System
ASV54_RS10730	COG2190	(PTS) system
ASV54_RS10730	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ASV54_RS10735	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
ASV54_RS10740	COG1307	EDD domain protein, DegV family
ASV54_RS10750	COG2873	o-acetylhomoserine
ASV54_RS10755	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
ASV54_RS10770	COG4120	Belongs to the binding-protein-dependent transport system permease family
ASV54_RS10780	COG0446	pyridine nucleotide-disulphide oxidoreductase
ASV54_RS10790	COG2084	Dehydrogenase
ASV54_RS10795	COG0861	Integral membrane protein TerC family
ASV54_RS10800	COG0110	maltose O-acetyltransferase activity
ASV54_RS10805	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
ASV54_RS10810	COG0140	phosphoribosyl-ATP diphosphatase activity
ASV54_RS10815	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
ASV54_RS10820	COG0107	imidazoleglycerol-phosphate synthase activity
ASV54_RS10825	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
ASV54_RS10830	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
ASV54_RS10835	COG0131	Imidazoleglycerol-phosphate dehydratase
ASV54_RS10840	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
ASV54_RS10845	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
ASV54_RS10850	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
ASV54_RS10855	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
ASV54_RS10880	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
ASV54_RS10895	COG3548	integral membrane protein
ASV54_RS10915	COG1368	sulfuric ester hydrolase activity
ASV54_RS10920	COG0584	glycerophosphoryl diester phosphodiesterase
ASV54_RS10935	COG0492	ferredoxin-NADP+ reductase activity
ASV54_RS10945	COG4932	domain protein
ASV54_RS10950	COG2326	polyphosphate kinase activity
ASV54_RS10955	COG0778	Nitroreductase
ASV54_RS10965	COG0328	RNA-DNA hybrid ribonuclease activity
ASV54_RS10970	COG4975	Glucose uptake
ASV54_RS10985	COG1349	DNA-binding transcription factor activity
ASV54_RS10990	COG1882	Formate acetyltransferase
ASV54_RS11010	COG1609	Transcriptional regulator
ASV54_RS11015	COG1737	Transcriptional regulator
ASV54_RS11020	COG0673	inositol 2-dehydrogenase activity
ASV54_RS11025	COG0673	inositol 2-dehydrogenase activity
ASV54_RS11030	COG0025	NhaP-type Na H and K H
ASV54_RS11035	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
ASV54_RS11040	COG1335	isochorismatase
ASV54_RS11050	COG1131	(ABC) transporter
ASV54_RS11055	COG1725	Transcriptional regulator
ASV54_RS11095	COG0028	Belongs to the TPP enzyme family
ASV54_RS11105	COG1073	alpha beta
ASV54_RS11110	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ASV54_RS11115	COG0626	cystathionine gamma-synthase activity
ASV54_RS11145	COG0095	Lipoate-protein ligase
ASV54_RS11150	COG1705	Flagellar rod assembly protein muramidase FlgJ
ASV54_RS11155	COG0589	response to stress
ASV54_RS11160	COG0564	pseudouridine synthase activity
ASV54_RS11175	COG4640	response to antibiotic
ASV54_RS11180	COG1396	sequence-specific DNA binding
ASV54_RS11195	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
ASV54_RS11205	COG2188	Transcriptional regulator
ASV54_RS11210	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
ASV54_RS11220	COG1418	mRNA catabolic process
ASV54_RS11250	COG1253	flavin adenine dinucleotide binding
ASV54_RS11255	COG1780	Probably involved in ribonucleotide reductase function
ASV54_RS11265	COG2814	Major facilitator Superfamily
ASV54_RS11270	COG0789	Transcriptional regulator
ASV54_RS11275	COG0604	alcohol dehydrogenase
ASV54_RS11285	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
ASV54_RS11295	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ASV54_RS11300	COG0436	Aminotransferase
ASV54_RS11305	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ASV54_RS11320	COG0583	DNA-binding transcription factor activity
ASV54_RS11325	COG0702	epimerase
ASV54_RS11335	COG1074	ATP-dependent DNA helicase activity
ASV54_RS11340	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
ASV54_RS11350	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
ASV54_RS11355	COG0284	orotidine-5'-phosphate decarboxylase activity
ASV54_RS11360	COG0167	dihydroorotate dehydrogenase activity
ASV54_RS11365	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
ASV54_RS11370	COG0505	Belongs to the CarA family
ASV54_RS11375	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
ASV54_RS11380	COG0540	Belongs to the ATCase OTCase family
ASV54_RS11385	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
ASV54_RS11390	COG2508	Transcriptional regulator
ASV54_RS11395	COG2233	PERMEase
ASV54_RS11400	COG2252	PERMEase
ASV54_RS11420	COG1215	transferase activity, transferring glycosyl groups
ASV54_RS11430	COG0151	Belongs to the GarS family
ASV54_RS11435	COG0138	bifunctional purine biosynthesis protein purh
ASV54_RS11440	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
ASV54_RS11445	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
ASV54_RS11455	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
ASV54_RS11460	COG0047	phosphoribosylformylglycinamidine synthase activity
ASV54_RS11465	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
ASV54_RS11470	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
ASV54_RS11475	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
ASV54_RS11490	COG1053	succinate dehydrogenase
ASV54_RS11490	COG0431	NADPH-dependent FMN reductase
ASV54_RS11490	COG3976	FMN-binding domain protein
ASV54_RS11495	COG3976	FMN-binding domain protein
ASV54_RS11495	COG1053	succinate dehydrogenase
ASV54_RS11495	COG0431	NADPH-dependent FMN reductase
ASV54_RS11500	COG0095	Lipoate-protein ligase
ASV54_RS11505	COG2365	Tyrosine phosphatase family
ASV54_RS11525	COG1136	(ABC) transporter
ASV54_RS11540	COG1725	Transcriptional regulator
ASV54_RS11545	COG1131	(ABC) transporter
ASV54_RS11555	COG0589	response to stress
ASV54_RS11565	COG2246	polysaccharide biosynthetic process
ASV54_RS11585	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
ASV54_RS11605	COG0366	Alpha amylase catalytic
ASV54_RS11615	COG0561	phosphatase activity
ASV54_RS11625	COG0110	maltose O-acetyltransferase activity
ASV54_RS11630	COG0494	nUDIX hydrolase
ASV54_RS11665	COG1827	regulation of RNA biosynthetic process
ASV54_RS11670	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
ASV54_RS11675	COG1309	transcriptional regulator
ASV54_RS11685	COG1131	(ABC) transporter
ASV54_RS11690	COG3048	D-serine ammonia-lyase activity
ASV54_RS11695	COG2723	6-phospho-beta-galactosidase activity
ASV54_RS11700	COG2723	6-phospho-beta-galactosidase activity
ASV54_RS11705	COG1447	Phosphotransferase system cellobiose-specific component IIA
ASV54_RS11710	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
ASV54_RS11715	COG2188	Transcriptional regulator
ASV54_RS11720	COG1216	Glycosyl transferase, family 2
ASV54_RS11735	COG0561	phosphatase activity
ASV54_RS11740	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
ASV54_RS11765	COG0716	FMN binding
ASV54_RS11785	COG0710	3-dehydroquinate dehydratase activity
ASV54_RS11790	COG0531	amino acid
ASV54_RS11835	COG4720	Psort location CytoplasmicMembrane, score
ASV54_RS11840	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
ASV54_RS11855	COG4990	cell redox homeostasis
ASV54_RS11880	COG1811	Na channel or pump
ASV54_RS11885	COG4978	Transcriptional regulator
ASV54_RS11885	COG0789	Transcriptional regulator
ASV54_RS11905	COG0577	efflux transmembrane transporter activity
ASV54_RS11910	COG1136	(ABC) transporter
ASV54_RS11950	COG2814	Major facilitator Superfamily
ASV54_RS11960	COG2814	Major facilitator Superfamily
ASV54_RS11970	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
ASV54_RS11975	COG2855	membrane
ASV54_RS11980	COG0583	DNA-binding transcription factor activity
ASV54_RS11990	COG0438	transferase activity, transferring glycosyl groups
ASV54_RS12005	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
ASV54_RS12015	COG4152	abc transporter atp-binding protein
ASV54_RS12025	COG4221	oxidoreductase activity
ASV54_RS12040	COG0789	Transcriptional regulator
ASV54_RS12060	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
ASV54_RS12085	COG0456	acetyltransferase
ASV54_RS12110	COG0583	DNA-binding transcription factor activity
ASV54_RS12120	COG1063	alcohol dehydrogenase
ASV54_RS12125	COG1028	Short-chain dehydrogenase reductase Sdr
ASV54_RS12150	COG4975	Glucose uptake
ASV54_RS12160	COG0656	L-ascorbic acid biosynthetic process
ASV54_RS12165	COG0583	DNA-binding transcription factor activity
ASV54_RS12185	COG4221	oxidoreductase activity
ASV54_RS12190	COG0656	L-ascorbic acid biosynthetic process
ASV54_RS12210	COG0589	response to stress
ASV54_RS12215	COG0110	maltose O-acetyltransferase activity
ASV54_RS12220	COG1011	Hydrolase
ASV54_RS12235	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
ASV54_RS12245	COG0667	Aldo Keto reductase
ASV54_RS12250	COG1132	(ABC) transporter
ASV54_RS12255	COG1132	(ABC) transporter
ASV54_RS12260	COG2814	Major facilitator Superfamily
ASV54_RS12270	COG1511	domain protein
ASV54_RS12270	COG1511	domain protein
ASV54_RS12280	COG0640	Transcriptional regulator
ASV54_RS12310	COG0488	(ABC) transporter
ASV54_RS12315	COG0561	phosphatase activity
ASV54_RS12325	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
ASV54_RS12340	COG2267	carboxylic ester hydrolase activity
ASV54_RS12345	COG0531	amino acid
ASV54_RS12350	COG2270	Major facilitator Superfamily
ASV54_RS12390	COG2200	EAL domain
ASV54_RS12400	COG1328	CTP reductase activity
ASV54_RS12410	COG0242	peptide deformylase activity
ASV54_RS12420	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
ASV54_RS12440	COG0583	DNA-binding transcription factor activity
ASV54_RS12450	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
ASV54_RS12510	COG0697	spore germination
ASV54_RS12535	COG1940	carbohydrate kinase activity
ASV54_RS12540	COG1132	(ABC) transporter
ASV54_RS12550	COG0778	Nitroreductase
ASV54_RS12555	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ASV54_RS12555	COG1263	PTS System
ASV54_RS12555	COG2190	(PTS) system
ASV54_RS12560	COG1116	anion transmembrane transporter activity
ASV54_RS12565	COG4120	Belongs to the binding-protein-dependent transport system permease family
ASV54_RS12595	COG0617	tRNA 3'-terminal CCA addition
ASV54_RS12595	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
ASV54_RS12595	COG3620	sequence-specific DNA binding
ASV54_RS12600	COG0410	ABC transporter
ASV54_RS12615	COG0559	Belongs to the binding-protein-dependent transport system permease family
ASV54_RS12635	COG5549	protein import
ASV54_RS12635	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ASV54_RS12640	COG2246	polysaccharide biosynthetic process
ASV54_RS12650	COG1914	H( )-stimulated, divalent metal cation uptake system
ASV54_RS12670	COG0640	Transcriptional regulator
ASV54_RS12685	COG1136	(ABC) transporter
ASV54_RS12685	COG0577	efflux transmembrane transporter activity
ASV54_RS12720	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
ASV54_RS12725	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
ASV54_RS12730	COG2723	6-phospho-beta-galactosidase activity
ASV54_RS12740	COG0789	Transcriptional regulator
ASV54_RS12745	COG0741	lytic transglycosylase activity
ASV54_RS12765	COG0803	Belongs to the bacterial solute-binding protein 9 family
ASV54_RS12790	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
ASV54_RS12805	COG4221	oxidoreductase activity
ASV54_RS12835	COG1028	Short-chain dehydrogenase reductase Sdr
ASV54_RS12850	COG1132	(ABC) transporter
ASV54_RS12855	COG1132	(ABC) transporter
ASV54_RS12865	COG1473	amidohydrolase
ASV54_RS12870	COG1028	Short-chain dehydrogenase reductase Sdr
ASV54_RS12885	COG0531	amino acid
ASV54_RS12910	COG2217	Heavy metal translocating P-type atpase
ASV54_RS12970	COG1063	alcohol dehydrogenase
ASV54_RS13010	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ASV54_RS13025	COG1733	regulation of RNA biosynthetic process
ASV54_RS13030	COG2814	Major facilitator Superfamily
ASV54_RS13040	COG0367	asparagine synthase
ASV54_RS13045	COG3279	Response regulator of the LytR AlgR family
ASV54_RS13060	COG1309	transcriptional regulator
ASV54_RS13070	COG1012	belongs to the aldehyde dehydrogenase family
ASV54_RS13085	COG1733	regulation of RNA biosynthetic process
ASV54_RS13090	COG0300	oxidoreductase activity
ASV54_RS13110	COG4989	oxidoreductase activity
ASV54_RS13115	COG0477	Major facilitator Superfamily
ASV54_RS13125	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
ASV54_RS13130	COG1120	ATPase activity
ASV54_RS13135	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ASV54_RS13140	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ASV54_RS13145	COG1309	transcriptional regulator
ASV54_RS13155	COG0640	Transcriptional regulator
ASV54_RS13160	COG2814	Major facilitator Superfamily
ASV54_RS13165	COG4221	oxidoreductase activity
ASV54_RS13170	COG0110	maltose O-acetyltransferase activity
ASV54_RS13175	COG1028	Short-chain dehydrogenase reductase Sdr
ASV54_RS13215	COG0481	GTPase activity
ASV54_RS13225	COG2816	NAD+ diphosphatase activity
ASV54_RS13235	COG3976	FMN-binding domain protein
ASV54_RS13235	COG1053	succinate dehydrogenase
ASV54_RS13235	COG0431	NADPH-dependent FMN reductase
ASV54_RS13245	COG0783	Belongs to the Dps family
ASV54_RS13255	COG2723	6-phospho-beta-galactosidase activity
ASV54_RS13260	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
ASV54_RS13280	COG0789	Transcriptional regulator
ASV54_RS13300	COG0693	protein deglycase activity
ASV54_RS13325	COG1136	(ABC) transporter
ASV54_RS13325	COG0577	efflux transmembrane transporter activity
ASV54_RS13335	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
ASV54_RS13350	COG1376	ErfK ybiS ycfS ynhG family protein
ASV54_RS13355	COG0656	L-ascorbic acid biosynthetic process
ASV54_RS13370	COG0477	Major facilitator Superfamily
ASV54_RS13410	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
ASV54_RS13420	COG3414	Phosphotransferase system galactitol-specific IIB component
ASV54_RS13425	COG3775	system Galactitol-specific IIC component
ASV54_RS13435	COG1349	DNA-binding transcription factor activity
ASV54_RS13440	COG1028	Short-chain dehydrogenase reductase Sdr
ASV54_RS13445	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
ASV54_RS13450	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
ASV54_RS13455	COG3775	system Galactitol-specific IIC component
ASV54_RS13460	COG3414	Phosphotransferase system galactitol-specific IIB component
ASV54_RS13495	COG2226	methyltransferase
ASV54_RS13500	COG0588	phosphoglycerate mutase activity
ASV54_RS13505	COG0628	permease
ASV54_RS13520	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
ASV54_RS13530	COG0515	serine threonine protein kinase
ASV54_RS13530	COG2815	serine threonine protein kinase
ASV54_RS13570	COG1247	-acetyltransferase
ASV54_RS13575	COG1686	Belongs to the peptidase S11 family
ASV54_RS13595	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
ASV54_RS13600	COG0516	GMP reductase activity
ASV54_RS13600	COG0517	IMP dehydrogenase activity
ASV54_RS13610	COG0012	GTP binding
ASV54_RS13615	COG4481	Protein conserved in bacteria
ASV54_RS13620	COG1475	DNA binding
ASV54_RS13625	COG1192	Involved in chromosome partitioning
ASV54_RS13635	COG0357	Ribosomal RNA small subunit methyltransferase G
ASV54_RS13640	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
ASV54_RS13655	COG0583	DNA-binding transcription factor activity
ASV54_RS13660	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ASV54_RS13665	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ASV54_RS13670	COG0765	amino acid transport
ASV54_RS13675	COG1126	abc transporter atp-binding protein
ASV54_RS13680	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ASV54_RS13705	COG1263	PTS System
ASV54_RS13705	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ASV54_RS13705	COG2190	(PTS) system
ASV54_RS13710	COG0366	Alpha amylase catalytic
ASV54_RS13715	COG1609	Transcriptional regulator
ASV54_RS13725	COG0390	transport system, permease component
ASV54_RS13730	COG4619	ABC transporter
ASV54_RS13735	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
ASV54_RS13750	COG0561	phosphatase activity
ASV54_RS13765	COG1263	PTS System
ASV54_RS13765	COG2190	(PTS) system
ASV54_RS13765	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ASV54_RS13795	COG0735	belongs to the Fur family
ASV54_RS13820	COG1380	Effector of murein hydrolase LrgA
ASV54_RS13830	COG1307	EDD domain protein, DegV family
ASV54_RS13840	COG2738	Putative neutral zinc metallopeptidase
ASV54_RS13845	COG1233	COG1233 Phytoene dehydrogenase and related
ASV54_RS13850	COG1562	ergosterol biosynthetic process
ASV54_RS13860	COG1929	Belongs to the glycerate kinase type-1 family
ASV54_RS13875	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
ASV54_RS13880	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
ASV54_RS13885	COG0516	GMP reductase activity
ASV54_RS13890	COG2365	Tyrosine phosphatase family
ASV54_RS13895	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ASV54_RS13905	COG0531	amino acid
ASV54_RS13910	COG3158	transport of potassium into the cell
ASV54_RS13915	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
ASV54_RS13920	COG0628	permease
ASV54_RS13925	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
ASV54_RS13940	COG1272	protein, Hemolysin III
ASV54_RS13945	COG0640	Transcriptional regulator
ASV54_RS13980	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
ASV54_RS13990	COG0302	gtp cyclohydrolase
ASV54_RS13995	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
ASV54_RS14015	COG0803	Belongs to the bacterial solute-binding protein 9 family
ASV54_RS14020	COG2814	Major facilitator Superfamily
ASV54_RS14050	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
ASV54_RS14055	COG1882	Formate acetyltransferase
ASV54_RS14060	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
ASV54_RS14070	COG2151	metal-sulfur cluster biosynthetic enzyme
ASV54_RS14075	COG4989	oxidoreductase activity
ASV54_RS14110	COG2217	Heavy metal translocating P-type atpase
ASV54_RS14120	COG2315	Protein conserved in bacteria
ASV54_RS14135	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
ASV54_RS14140	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
ASV54_RS14150	COG1757	Na H antiporter
ASV54_RS14155	COG1113	amino acid transport
ASV54_RS14165	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
ASV54_RS14180	COG1393	Belongs to the ArsC family
ASV54_RS14185	COG3189	MarR family transcriptional regulator
ASV54_RS14195	COG1194	a g-specific adenine glycosylase
ASV54_RS14210	COG0071	Belongs to the small heat shock protein (HSP20) family
ASV54_RS14230	COG0697	spore germination
ASV54_RS14245	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
ASV54_RS14270	COG0477	Major facilitator Superfamily
ASV54_RS14330	COG0737	Belongs to the 5'-nucleotidase family
ASV54_RS14340	COG0656	L-ascorbic acid biosynthetic process
ASV54_RS14360	COG1968	undecaprenyl-diphosphatase activity
ASV54_RS14365	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
ASV54_RS14400	COG2207	Transcriptional regulator
ASV54_RS14425	COG0076	glutamate decarboxylase activity
ASV54_RS14465	COG2226	methyltransferase
ASV54_RS14485	COG2217	Heavy metal translocating P-type atpase
ASV54_RS14490	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
ASV54_RS14495	COG3118	belongs to the thioredoxin family
ASV54_RS14500	COG1937	Protein conserved in bacteria
ASV54_RS14520	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
ASV54_RS14525	COG3590	peptidase
ASV54_RS14550	COG0446	pyridine nucleotide-disulphide oxidoreductase
ASV54_RS14600	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
ASV54_RS14610	COG1114	Component of the transport system for branched-chain amino acids
ASV54_RS14620	COG1874	Beta-galactosidase
ASV54_RS14625	COG1609	Transcriptional regulator
ASV54_RS14635	COG0477	Major facilitator Superfamily
ASV54_RS14655	COG2184	nucleotidyltransferase activity
ASV54_RS14660	COG2944	sequence-specific DNA binding
ASV54_RS14665	COG1609	Transcriptional regulator
ASV54_RS14670	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
ASV54_RS14675	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
ASV54_RS14680	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
ASV54_RS14700	COG2190	(PTS) system
ASV54_RS14700	COG2211	Major facilitator Superfamily
ASV54_RS14705	COG2017	converts alpha-aldose to the beta-anomer
ASV54_RS14710	COG1609	Transcriptional regulator
ASV54_RS14715	COG0667	Aldo Keto reductase
ASV54_RS14735	COG0710	3-dehydroquinate dehydratase activity
ASV54_RS14740	COG0738	Major facilitator superfamily
ASV54_RS14745	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
ASV54_RS14750	COG0583	DNA-binding transcription factor activity
ASV54_RS14755	COG0738	Major facilitator superfamily
ASV54_RS14765	COG2267	carboxylic ester hydrolase activity
ASV54_RS14770	COG2188	Transcriptional regulator
ASV54_RS14775	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
ASV54_RS14780	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
ASV54_RS14785	COG2971	BadF BadG BcrA BcrD
ASV54_RS14795	COG2723	6-phospho-beta-galactosidase activity
ASV54_RS14805	COG3711	transcriptional antiterminator
ASV54_RS14810	COG2723	6-phospho-beta-galactosidase activity
ASV54_RS14815	COG1053	succinate dehydrogenase
ASV54_RS14815	COG0431	NADPH-dependent FMN reductase
ASV54_RS14815	COG3976	FMN-binding domain protein
ASV54_RS14830	COG0604	alcohol dehydrogenase
ASV54_RS14835	COG4702	Belongs to the UPF0303 family
ASV54_RS14840	COG0673	inositol 2-dehydrogenase activity
ASV54_RS14845	COG2814	Major facilitator Superfamily
ASV54_RS14850	COG0673	inositol 2-dehydrogenase activity
ASV54_RS14855	COG1082	Xylose isomerase domain protein TIM barrel
ASV54_RS14860	COG0673	inositol 2-dehydrogenase activity
ASV54_RS14865	COG0673	inositol 2-dehydrogenase activity
ASV54_RS14870	COG2814	Major facilitator Superfamily
ASV54_RS14885	COG3775	system Galactitol-specific IIC component
ASV54_RS14900	COG1349	DNA-binding transcription factor activity
ASV54_RS14905	COG2207	Transcriptional regulator
ASV54_RS14910	COG2814	Major facilitator Superfamily
ASV54_RS14915	COG1070	Carbohydrate kinase
ASV54_RS14920	COG3254	rhamnose metabolic process
ASV54_RS14925	COG4806	L-rhamnose isomerase
ASV54_RS14930	COG0235	Class ii aldolase
ASV54_RS14945	COG0028	Belongs to the TPP enzyme family
ASV54_RS14950	COG1959	2 iron, 2 sulfur cluster binding
ASV54_RS14955	COG0028	Belongs to the TPP enzyme family
ASV54_RS14960	COG1304	FMN binding
ASV54_RS14975	COG4512	PFAM Accessory gene regulator B
ASV54_RS14995	COG1393	Belongs to the ArsC family
ASV54_RS15005	COG2261	transglycosylase associated protein
ASV54_RS15035	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
ASV54_RS15040	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ASV54_RS15060	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ASV54_RS15080	COG1737	Transcriptional regulator
ASV54_RS15085	COG1609	Transcriptional regulator
ASV54_RS15105	COG2160	L-arabinose isomerase activity
ASV54_RS15110	COG0110	maltose O-acetyltransferase activity
ASV54_RS15120	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
ASV54_RS15125	COG1349	DNA-binding transcription factor activity
ASV54_RS15135	COG3414	Phosphotransferase system galactitol-specific IIB component
ASV54_RS15140	COG3775	system Galactitol-specific IIC component
ASV54_RS15145	COG1063	alcohol dehydrogenase
ASV54_RS15160	COG3711	transcriptional antiterminator
ASV54_RS15180	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
ASV54_RS15195	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
ASV54_RS15210	COG2211	Major facilitator Superfamily
ASV54_RS15230	COG1263	PTS System
ASV54_RS15230	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ASV54_RS15230	COG2190	(PTS) system
ASV54_RS15235	COG2723	6-phospho-beta-galactosidase activity
ASV54_RS15240	COG0583	DNA-binding transcription factor activity
ASV54_RS15245	COG2223	nitrite transmembrane transporter activity
ASV54_RS15260	COG1960	acyl-CoA dehydrogenase activity
ASV54_RS15275	COG0318	PFAM AMP-dependent synthetase and ligase
ASV54_RS15285	COG1957	nucleoside hydrolase
ASV54_RS15300	COG3732	PTS system glucitol sorbitol-specific
ASV54_RS15305	COG3730	PTS system glucitol sorbitol-specific
ASV54_RS15315	COG3711	transcriptional antiterminator
ASV54_RS15315	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
ASV54_RS15325	COG2723	6-phospho-beta-galactosidase activity
ASV54_RS15330	COG1940	carbohydrate kinase activity
ASV54_RS15335	COG0383	alpha-mannosidase activity
ASV54_RS15345	COG2188	Transcriptional regulator
ASV54_RS15355	COG3842	ATPase activity
ASV54_RS15365	COG4753	response regulator
ASV54_RS15365	COG2207	Transcriptional regulator
ASV54_RS15370	COG2972	Histidine kinase
ASV54_RS15380	COG0366	Alpha amylase catalytic
ASV54_RS15385	COG1653	transport
ASV54_RS15390	COG0395	ABC-type sugar transport system, permease component
ASV54_RS15405	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
ASV54_RS15405	COG2207	Transcriptional regulator
ASV54_RS15410	COG1132	(ABC) transporter
ASV54_RS15415	COG1132	(ABC) transporter
ASV54_RS15420	COG2188	Transcriptional regulator
ASV54_RS15435	COG3732	PTS system glucitol sorbitol-specific
ASV54_RS15440	COG3730	PTS system glucitol sorbitol-specific
ASV54_RS15460	COG4975	Glucose uptake
ASV54_RS15465	COG1869	D-ribose catabolic process
ASV54_RS15475	COG1609	Transcriptional regulator
ASV54_RS15480	COG1454	alcohol dehydrogenase
ASV54_RS15480	COG1012	belongs to the aldehyde dehydrogenase family
ASV54_RS15495	COG1695	Transcriptional regulator
ASV54_RS15500	COG3479	Phenolic acid decarboxylase
ASV54_RS15515	COG1307	EDD domain protein, DegV family
ASV54_RS15555	COG0445	tRNA wobble uridine modification
ASV54_RS15560	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
ASV54_RS15565	COG1847	R3H domain protein
ASV54_RS15575	COG4166	transmembrane transport
ASV54_RS15580	COG0706	membrane insertase activity
ASV54_RS15585	COG0594	ribonuclease P activity
ASV54_RS15590	COG0230	Belongs to the bacterial ribosomal protein bL34 family
ASV54_RS15615	COG1846	Transcriptional regulator
ASV54_RS15620	COG0693	protein deglycase activity
ASV54_RS15625	COG1393	Belongs to the ArsC family
ASV54_RS15640	COG0446	pyridine nucleotide-disulphide oxidoreductase
ASV54_RS15655	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
ASV54_RS15725	COG1192	Involved in chromosome partitioning
ASV54_RS15745	COG1523	belongs to the glycosyl hydrolase 13 family
ASV54_RS15790	COG0562	UDP-galactopyranose mutase
ASV54_RS15800	COG3328	transposase activity
ASV54_RS15810	COG2261	transglycosylase associated protein
ASV54_RS15870	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
ASV54_RS15875	COG1461	Dihydroxyacetone kinase
ASV54_RS15880	COG2376	Dihydroxyacetone kinase
ASV54_RS15900	COG1388	LysM domain
ASV54_RS15935	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
ASV54_RS15995	COG2826	transposase and inactivated derivatives, IS30 family
ASV54_RS16050	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ASV54_RS16060	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ASV54_RS16110	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
ASV54_RS16125	COG0446	pyridine nucleotide-disulphide oxidoreductase
ASV54_RS16140	COG1393	Belongs to the ArsC family
ASV54_RS16145	COG0693	protein deglycase activity
ASV54_RS16160	COG1621	beta-fructofuranosidase activity
ASV54_RS16185	COG0028	Belongs to the TPP enzyme family
ASV54_RS16190	COG1268	BioY protein
ASV54_RS16205	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
ASV54_RS16275	COG0446	pyridine nucleotide-disulphide oxidoreductase
ASV54_RS16285	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
ASV54_RS16295	COG2826	transposase and inactivated derivatives, IS30 family
ASV54_RS16325	COG4716	Myosin-crossreactive antigen
ASV54_RS16330	COG4876	unkown
ASV54_RS16345	COG2814	Major facilitator Superfamily
ASV54_RS16350	COG5039	Polysaccharide pyruvyl transferase
ASV54_RS16355	COG2814	Major facilitator Superfamily
ASV54_RS16360	COG2261	transglycosylase associated protein
ASV54_RS16380	COG0028	Belongs to the TPP enzyme family
ASV54_RS16400	COG1192	Involved in chromosome partitioning
ASV54_RS16410	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
ASV54_RS16445	COG2826	transposase and inactivated derivatives, IS30 family
ASV54_RS16490	COG0551	DNA topoisomerase type I activity
ASV54_RS16490	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
ASV54_RS16510	COG2801	Transposase and inactivated derivatives
ASV54_RS16525	COG2217	Heavy metal translocating P-type atpase
ASV54_RS16545	COG0531	amino acid
ASV54_RS16560	COG2826	transposase and inactivated derivatives, IS30 family
ASV54_RS16600	COG0277	FAD linked oxidase domain protein
ASV54_RS16610	COG1846	Transcriptional regulator
ASV54_RS16620	COG2801	Transposase and inactivated derivatives
ASV54_RS16650	COG1192	Involved in chromosome partitioning
ASV54_RS16660	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
ASV54_RS16670	COG0366	Alpha amylase catalytic
ASV54_RS16680	COG2211	Major facilitator Superfamily
ASV54_RS16740	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
ASV54_RS16755	COG0783	Belongs to the Dps family
ASV54_RS16810	COG0582	viral genome integration into host DNA
ASV54_RS16815	COG2217	Heavy metal translocating P-type atpase
ASV54_RS16820	COG0640	Transcriptional regulator
ASV54_RS16825	COG2801	Transposase and inactivated derivatives
ASV54_RS16890	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
ASV54_RS16950	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ASV54_RS16960	COG2096	Adenosyltransferase
ASV54_RS16970	COG2826	transposase and inactivated derivatives, IS30 family
ASV54_RS16980	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
ASV54_RS17120	COG0463	Glycosyl transferase, family 2
ASV54_RS17130	COG0586	Pfam SNARE associated Golgi protein
ASV54_RS17135	COG5002	protein histidine kinase activity
ASV54_RS17140	COG0745	RESPONSE REGULATOR receiver
ASV54_RS17150	COG2217	Heavy metal translocating P-type atpase
ASV54_RS17165	COG2814	Major facilitator Superfamily
ASV54_RS17190	COG0446	pyridine nucleotide-disulphide oxidoreductase
ASV54_RS17275	COG2801	Transposase and inactivated derivatives
ASV54_RS17300	COG0582	viral genome integration into host DNA
ASV54_RS17405	COG0783	Belongs to the Dps family
ASV54_RS17605	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase