locus-tag	class	description
JH395_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
JH395_RS00010	COG0592	DNA-directed DNA polymerase activity
JH395_RS00015	COG2501	S4 domain
JH395_RS00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
JH395_RS00025	COG0187	DNA topoisomerase II activity
JH395_RS00035	COG0360	Binds together with S18 to 16S ribosomal RNA
JH395_RS00040	COG0629	single-stranded DNA binding
JH395_RS00045	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
JH395_RS00055	COG0359	binds to the 23S rRNA
JH395_RS00060	COG0305	Participates in initiation and elongation during chromosome replication
JH395_RS00065	COG2814	Major facilitator Superfamily
JH395_RS00070	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
JH395_RS00075	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
JH395_RS00080	COG4166	transmembrane transport
JH395_RS00085	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
JH395_RS00090	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
JH395_RS00095	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
JH395_RS00100	COG0297	glycogen (starch) synthase activity
JH395_RS00105	COG0058	SHG alpha-glucan phosphorylase activity
JH395_RS00110	COG0366	Alpha amylase catalytic
JH395_RS00110	COG3103	Sh3 type 3 domain protein
JH395_RS00125	COG1554	hydrolase, family 65, central catalytic
JH395_RS00135	COG1278	Cold shock
JH395_RS00150	COG0745	RESPONSE REGULATOR receiver
JH395_RS00155	COG5002	protein histidine kinase activity
JH395_RS00165	COG4853	Protein conserved in bacteria
JH395_RS00170	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
JH395_RS00175	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
JH395_RS00180	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
JH395_RS00205	COG0464	growth
JH395_RS00220	COG1012	belongs to the aldehyde dehydrogenase family
JH395_RS00225	COG3586	endonuclease activity
JH395_RS00230	COG1573	uracil-dna glycosylase
JH395_RS00255	COG3976	FMN-binding domain protein
JH395_RS00255	COG0431	NADPH-dependent FMN reductase
JH395_RS00255	COG1053	succinate dehydrogenase
JH395_RS00260	COG0471	metal ion transport
JH395_RS00275	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
JH395_RS00280	COG1028	Short-chain dehydrogenase reductase Sdr
JH395_RS00290	COG0778	Nitroreductase
JH395_RS00295	COG2508	Transcriptional regulator
JH395_RS00300	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
JH395_RS00305	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
JH395_RS00315	COG2365	Tyrosine phosphatase family
JH395_RS00320	COG2368	4-hydroxyphenylacetate
JH395_RS00340	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
JH395_RS00370	COG0604	alcohol dehydrogenase
JH395_RS00390	COG2267	carboxylic ester hydrolase activity
JH395_RS00395	COG3022	response to hydroperoxide
JH395_RS00405	COG4166	transmembrane transport
JH395_RS00430	COG1122	ATPase activity
JH395_RS00435	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
JH395_RS00440	COG0310	cobalt ion transport
JH395_RS00445	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
JH395_RS00450	COG3875	lactate racemase activity
JH395_RS00455	COG1691	(AIR) carboxylase
JH395_RS00460	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
JH395_RS00465	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
JH395_RS00470	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
JH395_RS00475	COG1606	tRNA processing
JH395_RS00485	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
JH395_RS00490	COG0351	phosphomethylpyrimidine kinase
JH395_RS00495	COG0352	thiamine-phosphate diphosphorylase activity
JH395_RS00505	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
JH395_RS00520	COG1113	amino acid transport
JH395_RS00530	COG2267	carboxylic ester hydrolase activity
JH395_RS00540	COG1983	PspC domain protein
JH395_RS00580	COG2807	transmembrane transport
JH395_RS00585	COG0656	L-ascorbic acid biosynthetic process
JH395_RS00590	COG0667	Aldo Keto reductase
JH395_RS00620	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
JH395_RS00625	COG1122	ATPase activity
JH395_RS00630	COG4720	Psort location CytoplasmicMembrane, score
JH395_RS00640	COG2188	Transcriptional regulator
JH395_RS00665	COG1028	Short-chain dehydrogenase reductase Sdr
JH395_RS00670	COG1131	(ABC) transporter
JH395_RS00685	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
JH395_RS00690	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
JH395_RS00695	COG1309	transcriptional regulator
JH395_RS00700	COG2376	Dihydroxyacetone kinase
JH395_RS00705	COG2376	Dihydroxyacetone kinase
JH395_RS00710	COG1461	Dihydroxyacetone kinase
JH395_RS00715	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
JH395_RS00720	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
JH395_RS00725	COG1609	Transcriptional regulator
JH395_RS00730	COG1609	Transcriptional regulator
JH395_RS00735	COG0366	Alpha amylase catalytic
JH395_RS00740	COG2182	Extracellular solute-binding protein
JH395_RS00745	COG1175	transmembrane transport
JH395_RS00750	COG3833	ABC-type maltose transport systems, permease component
JH395_RS00765	COG3842	ATPase activity
JH395_RS00815	COG1757	Na H antiporter
JH395_RS00840	COG4166	transmembrane transport
JH395_RS00845	COG4166	transmembrane transport
JH395_RS00855	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
JH395_RS00860	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
JH395_RS00865	COG0406	alpha-ribazole phosphatase activity
JH395_RS00870	COG0667	Aldo Keto reductase
JH395_RS00900	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
JH395_RS00905	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
JH395_RS00910	COG0488	(ABC) transporter
JH395_RS00920	COG4172	Belongs to the ABC transporter superfamily
JH395_RS00930	COG0386	Belongs to the glutathione peroxidase family
JH395_RS00940	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
JH395_RS00955	COG0363	glucosamine-6-phosphate deaminase activity
JH395_RS00965	COG2213	PTS system mannitol-specific
JH395_RS00975	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
JH395_RS00980	COG0246	Mannitol dehydrogenase
JH395_RS00990	COG3118	belongs to the thioredoxin family
JH395_RS01020	COG0431	NADPH-dependent FMN reductase
JH395_RS01025	COG2188	Transcriptional regulator
JH395_RS01030	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
JH395_RS01045	COG3964	amidohydrolase
JH395_RS01065	COG1045	serine acetyltransferase
JH395_RS01070	COG0626	cystathionine gamma-synthase activity
JH395_RS01075	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
JH395_RS01100	COG2188	Transcriptional regulator
JH395_RS01105	COG0366	Alpha amylase catalytic
JH395_RS01110	COG2190	(PTS) system
JH395_RS01110	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JH395_RS01110	COG1263	PTS System
JH395_RS01115	COG1263	PTS System
JH395_RS01115	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JH395_RS01115	COG2190	(PTS) system
JH395_RS01125	COG0163	prenyltransferase activity
JH395_RS01135	COG1959	2 iron, 2 sulfur cluster binding
JH395_RS01140	COG1309	transcriptional regulator
JH395_RS01145	COG1914	H( )-stimulated, divalent metal cation uptake system
JH395_RS01165	COG2814	Major facilitator Superfamily
JH395_RS01175	COG5002	protein histidine kinase activity
JH395_RS01180	COG0745	RESPONSE REGULATOR receiver
JH395_RS01190	COG1737	Transcriptional regulator
JH395_RS01195	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
JH395_RS01210	COG1316	TRANSCRIPTIONal
JH395_RS01215	COG0277	FAD linked oxidase domain protein
JH395_RS01225	COG2357	RelA SpoT domain protein
JH395_RS01235	COG2409	Drug exporters of the RND superfamily
JH395_RS01235	COG1033	growth of symbiont in host cell
JH395_RS01240	COG2818	Glycosylase
JH395_RS01250	COG0577	efflux transmembrane transporter activity
JH395_RS01255	COG1136	(ABC) transporter
JH395_RS01270	COG0741	lytic transglycosylase activity
JH395_RS01275	COG1388	LysM domain
JH395_RS01275	COG3942	CHAP domain
JH395_RS01305	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
JH395_RS01315	COG1846	Transcriptional regulator
JH395_RS01320	COG1252	NADH dehydrogenase
JH395_RS01360	COG3842	ATPase activity
JH395_RS01390	COG1725	Transcriptional regulator
JH395_RS01395	COG1131	(ABC) transporter
JH395_RS01405	COG1012	belongs to the aldehyde dehydrogenase family
JH395_RS01405	COG1454	alcohol dehydrogenase
JH395_RS01440	COG1268	BioY protein
JH395_RS01460	COG2011	ABC-type metal ion transport system permease component
JH395_RS01465	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
JH395_RS01470	COG0436	Aminotransferase
JH395_RS01480	COG1682	transport, permease protein
JH395_RS01485	COG1134	teichoic acid transport
JH395_RS01500	COG2814	Major facilitator Superfamily
JH395_RS01505	COG0004	ammonium transporteR
JH395_RS01525	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
JH395_RS01535	COG3759	membrane
JH395_RS01540	COG1881	PFAM PEBP family protein
JH395_RS01570	COG0300	oxidoreductase activity
JH395_RS01585	COG1125	glycine betaine transport
JH395_RS01595	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
JH395_RS01605	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
JH395_RS01660	COG0110	maltose O-acetyltransferase activity
JH395_RS01670	COG0561	phosphatase activity
JH395_RS01680	COG0561	phosphatase activity
JH395_RS01685	COG1114	Component of the transport system for branched-chain amino acids
JH395_RS01725	COG0463	Glycosyl transferase, family 2
JH395_RS01745	COG3279	Response regulator of the LytR AlgR family
JH395_RS01755	COG2826	transposase and inactivated derivatives, IS30 family
JH395_RS01775	COG2274	protein secretion by the type I secretion system
JH395_RS01810	COG3973	AAA domain
JH395_RS01815	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
JH395_RS01820	COG0180	Tryptophanyl-tRNA synthetase
JH395_RS01825	COG2188	Transcriptional regulator
JH395_RS01830	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
JH395_RS01845	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
JH395_RS01850	COG2723	6-phospho-beta-galactosidase activity
JH395_RS01855	COG1940	carbohydrate kinase activity
JH395_RS01865	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
JH395_RS01880	COG0248	Ppx GppA phosphatase
JH395_RS01895	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
JH395_RS01900	COG1801	Protein of unknown function DUF72
JH395_RS01910	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
JH395_RS01910	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
JH395_RS01915	COG2814	Major facilitator Superfamily
JH395_RS01920	COG0084	hydrolase, TatD family'
JH395_RS01925	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
JH395_RS01930	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
JH395_RS01935	COG4466	Protein conserved in bacteria
JH395_RS01940	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
JH395_RS01945	COG1073	alpha beta
JH395_RS01950	COG1121	(ABC) transporter
JH395_RS01955	COG1108	ABC-type Mn2 Zn2 transport systems permease components
JH395_RS01955	COG1321	iron dependent repressor
JH395_RS01980	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
JH395_RS01985	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
JH395_RS01995	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
JH395_RS02000	COG2826	transposase and inactivated derivatives, IS30 family
JH395_RS02025	COG0735	belongs to the Fur family
JH395_RS02055	COG1263	PTS System
JH395_RS02055	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JH395_RS02055	COG2190	(PTS) system
JH395_RS02070	COG3711	transcriptional antiterminator
JH395_RS02070	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
JH395_RS02075	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JH395_RS02075	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JH395_RS02075	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
JH395_RS02080	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JH395_RS02085	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JH395_RS02085	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JH395_RS02085	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
JH395_RS02090	COG0383	alpha-mannosidase activity
JH395_RS02100	COG0561	phosphatase activity
JH395_RS02115	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
JH395_RS02120	COG4619	ABC transporter
JH395_RS02125	COG0390	transport system, permease component
JH395_RS02135	COG1609	Transcriptional regulator
JH395_RS02140	COG0366	Alpha amylase catalytic
JH395_RS02145	COG1263	PTS System
JH395_RS02145	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JH395_RS02145	COG2190	(PTS) system
JH395_RS02170	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JH395_RS02175	COG1126	abc transporter atp-binding protein
JH395_RS02180	COG0765	amino acid transport
JH395_RS02185	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JH395_RS02190	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
JH395_RS02195	COG0583	DNA-binding transcription factor activity
JH395_RS02210	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
JH395_RS02215	COG0357	Ribosomal RNA small subunit methyltransferase G
JH395_RS02225	COG1192	Involved in chromosome partitioning
JH395_RS02230	COG1475	DNA binding
JH395_RS02235	COG4481	Protein conserved in bacteria
JH395_RS02240	COG0012	GTP binding
JH395_RS02250	COG0516	GMP reductase activity
JH395_RS02250	COG0517	IMP dehydrogenase activity
JH395_RS02255	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
JH395_RS02275	COG1686	Belongs to the peptidase S11 family
JH395_RS02280	COG1247	-acetyltransferase
JH395_RS02315	COG2815	serine threonine protein kinase
JH395_RS02315	COG0515	serine threonine protein kinase
JH395_RS02330	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
JH395_RS02340	COG1940	carbohydrate kinase activity
JH395_RS02340	COG1846	Transcriptional regulator
JH395_RS02345	COG0628	permease
JH395_RS02350	COG0588	phosphoglycerate mutase activity
JH395_RS02360	COG2801	Transposase and inactivated derivatives
JH395_RS02380	COG1028	Short-chain dehydrogenase reductase Sdr
JH395_RS02385	COG0110	maltose O-acetyltransferase activity
JH395_RS02390	COG4221	oxidoreductase activity
JH395_RS02400	COG1309	transcriptional regulator
JH395_RS02405	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JH395_RS02410	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JH395_RS02415	COG1120	ATPase activity
JH395_RS02420	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
JH395_RS02430	COG0477	Major facilitator Superfamily
JH395_RS02435	COG4989	oxidoreductase activity
JH395_RS02455	COG0300	oxidoreductase activity
JH395_RS02460	COG1733	regulation of RNA biosynthetic process
JH395_RS02475	COG1012	belongs to the aldehyde dehydrogenase family
JH395_RS02485	COG1309	transcriptional regulator
JH395_RS02495	COG3279	Response regulator of the LytR AlgR family
JH395_RS02500	COG0367	asparagine synthase
JH395_RS02510	COG2814	Major facilitator Superfamily
JH395_RS02515	COG1733	regulation of RNA biosynthetic process
JH395_RS02520	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
JH395_RS02560	COG1063	alcohol dehydrogenase
JH395_RS02615	COG2217	Heavy metal translocating P-type atpase
JH395_RS02635	COG0531	amino acid
JH395_RS02655	COG1028	Short-chain dehydrogenase reductase Sdr
JH395_RS02660	COG1473	amidohydrolase
JH395_RS02670	COG1132	(ABC) transporter
JH395_RS02675	COG1132	(ABC) transporter
JH395_RS02690	COG1028	Short-chain dehydrogenase reductase Sdr
JH395_RS02720	COG4221	oxidoreductase activity
JH395_RS02735	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
JH395_RS02760	COG0803	Belongs to the bacterial solute-binding protein 9 family
JH395_RS02780	COG0741	lytic transglycosylase activity
JH395_RS02785	COG0789	Transcriptional regulator
JH395_RS02795	COG2723	6-phospho-beta-galactosidase activity
JH395_RS02800	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
JH395_RS02805	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
JH395_RS02840	COG0577	efflux transmembrane transporter activity
JH395_RS02840	COG1136	(ABC) transporter
JH395_RS02850	COG0640	Transcriptional regulator
JH395_RS02870	COG1914	H( )-stimulated, divalent metal cation uptake system
JH395_RS02880	COG2246	polysaccharide biosynthetic process
JH395_RS02885	COG5549	protein import
JH395_RS02885	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
JH395_RS02915	COG0410	ABC transporter
JH395_RS02920	COG3620	sequence-specific DNA binding
JH395_RS02920	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
JH395_RS02920	COG0617	tRNA 3'-terminal CCA addition
JH395_RS02950	COG4120	Belongs to the binding-protein-dependent transport system permease family
JH395_RS02955	COG1116	anion transmembrane transporter activity
JH395_RS02960	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JH395_RS02960	COG2190	(PTS) system
JH395_RS02960	COG1263	PTS System
JH395_RS02965	COG0778	Nitroreductase
JH395_RS02975	COG1132	(ABC) transporter
JH395_RS02980	COG1940	carbohydrate kinase activity
JH395_RS03005	COG0697	spore germination
JH395_RS03050	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
JH395_RS03060	COG0583	DNA-binding transcription factor activity
JH395_RS03075	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
JH395_RS03085	COG0242	peptide deformylase activity
JH395_RS03095	COG1328	CTP reductase activity
JH395_RS03105	COG2200	EAL domain
JH395_RS03145	COG2270	Major facilitator Superfamily
JH395_RS03160	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
JH395_RS03170	COG0561	phosphatase activity
JH395_RS03175	COG0488	(ABC) transporter
JH395_RS03205	COG0640	Transcriptional regulator
JH395_RS03215	COG1511	domain protein
JH395_RS03215	COG1511	domain protein
JH395_RS03225	COG2814	Major facilitator Superfamily
JH395_RS03230	COG1132	(ABC) transporter
JH395_RS03235	COG1132	(ABC) transporter
JH395_RS03240	COG0667	Aldo Keto reductase
JH395_RS03250	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
JH395_RS03265	COG1011	Hydrolase
JH395_RS03270	COG0110	maltose O-acetyltransferase activity
JH395_RS03275	COG0589	response to stress
JH395_RS03285	COG1028	Short-chain dehydrogenase reductase Sdr
JH395_RS03290	COG1063	alcohol dehydrogenase
JH395_RS03300	COG0583	DNA-binding transcription factor activity
JH395_RS03325	COG0456	acetyltransferase
JH395_RS03350	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
JH395_RS03370	COG0789	Transcriptional regulator
JH395_RS03385	COG4221	oxidoreductase activity
JH395_RS03395	COG4152	abc transporter atp-binding protein
JH395_RS03400	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
JH395_RS03415	COG0438	transferase activity, transferring glycosyl groups
JH395_RS03425	COG0583	DNA-binding transcription factor activity
JH395_RS03430	COG2855	membrane
JH395_RS03435	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
JH395_RS03445	COG2814	Major facilitator Superfamily
JH395_RS03455	COG2814	Major facilitator Superfamily
JH395_RS03495	COG1136	(ABC) transporter
JH395_RS03500	COG0577	efflux transmembrane transporter activity
JH395_RS03515	COG0789	Transcriptional regulator
JH395_RS03515	COG4978	Transcriptional regulator
JH395_RS03520	COG1811	Na channel or pump
JH395_RS03535	COG4990	cell redox homeostasis
JH395_RS03550	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
JH395_RS03555	COG4720	Psort location CytoplasmicMembrane, score
JH395_RS03600	COG0531	amino acid
JH395_RS03605	COG0710	3-dehydroquinate dehydratase activity
JH395_RS03625	COG0716	FMN binding
JH395_RS03650	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
JH395_RS03655	COG0561	phosphatase activity
JH395_RS03670	COG1216	Glycosyl transferase, family 2
JH395_RS03675	COG2188	Transcriptional regulator
JH395_RS03680	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
JH395_RS03685	COG1447	Phosphotransferase system cellobiose-specific component IIA
JH395_RS03690	COG2723	6-phospho-beta-galactosidase activity
JH395_RS03695	COG2723	6-phospho-beta-galactosidase activity
JH395_RS03700	COG3048	D-serine ammonia-lyase activity
JH395_RS03705	COG1131	(ABC) transporter
JH395_RS03715	COG1309	transcriptional regulator
JH395_RS03720	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
JH395_RS03725	COG1827	regulation of RNA biosynthetic process
JH395_RS03755	COG0494	nUDIX hydrolase
JH395_RS03760	COG0110	maltose O-acetyltransferase activity
JH395_RS03770	COG0561	phosphatase activity
JH395_RS03780	COG0366	Alpha amylase catalytic
JH395_RS03800	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
JH395_RS03820	COG2246	polysaccharide biosynthetic process
JH395_RS03830	COG0589	response to stress
JH395_RS03840	COG1131	(ABC) transporter
JH395_RS03845	COG1725	Transcriptional regulator
JH395_RS03860	COG1136	(ABC) transporter
JH395_RS03880	COG2365	Tyrosine phosphatase family
JH395_RS03885	COG0095	Lipoate-protein ligase
JH395_RS03890	COG3976	FMN-binding domain protein
JH395_RS03890	COG1053	succinate dehydrogenase
JH395_RS03890	COG0431	NADPH-dependent FMN reductase
JH395_RS03895	COG3976	FMN-binding domain protein
JH395_RS03895	COG1053	succinate dehydrogenase
JH395_RS03895	COG0431	NADPH-dependent FMN reductase
JH395_RS03905	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
JH395_RS03910	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
JH395_RS03915	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
JH395_RS03920	COG0047	phosphoribosylformylglycinamidine synthase activity
JH395_RS03925	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
JH395_RS03935	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
JH395_RS03940	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
JH395_RS03945	COG0138	bifunctional purine biosynthesis protein purh
JH395_RS03950	COG0151	Belongs to the GarS family
JH395_RS03960	COG1215	transferase activity, transferring glycosyl groups
JH395_RS03980	COG2252	PERMEase
JH395_RS03985	COG2233	PERMEase
JH395_RS03990	COG2508	Transcriptional regulator
JH395_RS03995	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
JH395_RS04000	COG0540	Belongs to the ATCase OTCase family
JH395_RS04005	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
JH395_RS04010	COG0505	Belongs to the CarA family
JH395_RS04015	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
JH395_RS04020	COG0167	dihydroorotate dehydrogenase activity
JH395_RS04025	COG0284	orotidine-5'-phosphate decarboxylase activity
JH395_RS04030	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
JH395_RS04040	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
JH395_RS04045	COG1074	ATP-dependent DNA helicase activity
JH395_RS04055	COG0702	epimerase
JH395_RS04060	COG0583	DNA-binding transcription factor activity
JH395_RS04070	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
JH395_RS04075	COG0436	Aminotransferase
JH395_RS04080	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
JH395_RS04085	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
JH395_RS04095	COG0604	alcohol dehydrogenase
JH395_RS04100	COG0789	Transcriptional regulator
JH395_RS04105	COG2814	Major facilitator Superfamily
JH395_RS04110	COG0025	NhaP-type Na H and K H
JH395_RS04115	COG1780	Probably involved in ribonucleotide reductase function
JH395_RS04120	COG1253	flavin adenine dinucleotide binding
JH395_RS04150	COG1418	mRNA catabolic process
JH395_RS04160	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
JH395_RS04165	COG2188	Transcriptional regulator
JH395_RS04175	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
JH395_RS04190	COG1396	sequence-specific DNA binding
JH395_RS04215	COG0564	pseudouridine synthase activity
JH395_RS04220	COG0589	response to stress
JH395_RS04225	COG1705	Flagellar rod assembly protein muramidase FlgJ
JH395_RS04230	COG0095	Lipoate-protein ligase
JH395_RS04260	COG0626	cystathionine gamma-synthase activity
JH395_RS04265	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
JH395_RS04270	COG1073	alpha beta
JH395_RS04280	COG0028	Belongs to the TPP enzyme family
JH395_RS04320	COG1725	Transcriptional regulator
JH395_RS04325	COG1131	(ABC) transporter
JH395_RS04335	COG1335	isochorismatase
JH395_RS04345	COG0025	NhaP-type Na H and K H
JH395_RS04350	COG0673	inositol 2-dehydrogenase activity
JH395_RS04355	COG0673	inositol 2-dehydrogenase activity
JH395_RS04365	COG1609	Transcriptional regulator
JH395_RS04375	COG0328	RNA-DNA hybrid ribonuclease activity
JH395_RS04385	COG0778	Nitroreductase
JH395_RS04390	COG2326	polyphosphate kinase activity
JH395_RS04405	COG0492	ferredoxin-NADP+ reductase activity
JH395_RS04410	COG0584	glycerophosphoryl diester phosphodiesterase
JH395_RS04415	COG1368	sulfuric ester hydrolase activity
JH395_RS04435	COG3548	integral membrane protein
JH395_RS04450	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
JH395_RS04460	COG0300	oxidoreductase activity
JH395_RS04465	COG0789	Transcriptional regulator
JH395_RS04485	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
JH395_RS04490	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
JH395_RS04495	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
JH395_RS04500	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
JH395_RS04505	COG0131	Imidazoleglycerol-phosphate dehydratase
JH395_RS04510	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
JH395_RS04515	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
JH395_RS04520	COG0107	imidazoleglycerol-phosphate synthase activity
JH395_RS04525	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
JH395_RS04530	COG0140	phosphoribosyl-ATP diphosphatase activity
JH395_RS04535	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
JH395_RS04540	COG0110	maltose O-acetyltransferase activity
JH395_RS04545	COG0861	Integral membrane protein TerC family
JH395_RS04550	COG2084	Dehydrogenase
JH395_RS04555	COG0446	pyridine nucleotide-disulphide oxidoreductase
JH395_RS04565	COG4120	Belongs to the binding-protein-dependent transport system permease family
JH395_RS04575	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
JH395_RS04580	COG2873	o-acetylhomoserine
JH395_RS04590	COG1307	EDD domain protein, DegV family
JH395_RS04595	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
JH395_RS04600	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JH395_RS04600	COG2190	(PTS) system
JH395_RS04600	COG1263	PTS System
JH395_RS04620	COG0488	(ABC) transporter
JH395_RS04640	COG1522	sequence-specific DNA binding
JH395_RS04645	COG0791	NLP P60 protein
JH395_RS04665	COG0477	Major facilitator Superfamily
JH395_RS04690	COG3830	Belongs to the UPF0237 family
JH395_RS04695	COG2848	UPF0210 protein
JH395_RS04700	COG0745	RESPONSE REGULATOR receiver
JH395_RS04705	COG5002	protein histidine kinase activity
JH395_RS04705	COG3850	Histidine kinase
JH395_RS04710	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
JH395_RS04715	COG4975	Glucose uptake
JH395_RS04720	COG0166	Belongs to the GPI family
JH395_RS04730	COG0577	efflux transmembrane transporter activity
JH395_RS04730	COG1136	(ABC) transporter
JH395_RS04740	COG1132	(ABC) transporter
JH395_RS04750	COG4886	Leucine-rich repeat (LRR) protein
JH395_RS04750	COG4932	domain protein
JH395_RS04805	COG1192	Involved in chromosome partitioning
JH395_RS04860	COG1396	sequence-specific DNA binding
JH395_RS05005	COG2868	ribosomal protein
JH395_RS05120	COG0726	polysaccharide deacetylase
JH395_RS05135	COG1132	(ABC) transporter
JH395_RS05150	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
JH395_RS05160	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
JH395_RS05165	COG1482	cell wall glycoprotein biosynthetic process
JH395_RS05170	COG3442	glutamine amidotransferase
JH395_RS05175	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
JH395_RS05180	COG1435	thymidine kinase activity
JH395_RS05185	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
JH395_RS05190	COG2890	protein-(glutamine-N5) methyltransferase activity
JH395_RS05195	COG0009	L-threonylcarbamoyladenylate synthase
JH395_RS05200	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
JH395_RS05205	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
JH395_RS05215	COG2233	PERMEase
JH395_RS05220	COG0356	it plays a direct role in the translocation of protons across the membrane
JH395_RS05225	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
JH395_RS05230	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
JH395_RS05235	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
JH395_RS05240	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
JH395_RS05245	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
JH395_RS05250	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
JH395_RS05255	COG0355	proton-transporting ATP synthase activity, rotational mechanism
JH395_RS05260	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
JH395_RS05270	COG1077	Cell shape determining protein MreB Mrl
JH395_RS05275	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
JH395_RS05285	COG0772	Belongs to the SEDS family
JH395_RS05290	COG0509	glycine decarboxylation via glycine cleavage system
JH395_RS05295	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
JH395_RS05300	COG2011	ABC-type metal ion transport system permease component
JH395_RS05305	COG1464	Belongs to the NlpA lipoprotein family
JH395_RS05325	COG1181	Belongs to the D-alanine--D-alanine ligase family
JH395_RS05345	COG0589	response to stress
JH395_RS05355	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
JH395_RS05360	COG2918	glutathione biosynthetic process
JH395_RS05360	COG0189	ligase activity
JH395_RS05365	COG0640	Transcriptional regulator
JH395_RS05380	COG4493	Belongs to the UPF0637 family
JH395_RS05385	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
JH395_RS05390	COG1956	GAF domain-containing protein
JH395_RS05395	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
JH395_RS05400	COG1104	cysteine desulfurase activity
JH395_RS05405	COG0301	tRNA thio-modification
JH395_RS05410	COG1181	Belongs to the D-alanine--D-alanine ligase family
JH395_RS05410	COG2918	glutathione biosynthetic process
JH395_RS05420	COG0525	valine-tRNA ligase activity
JH395_RS05425	COG0285	dihydrofolate synthase activity
JH395_RS05430	COG2003	Belongs to the UPF0758 family
JH395_RS05435	COG1077	Cell shape determining protein MreB Mrl
JH395_RS05440	COG1792	Involved in formation and maintenance of cell shape
JH395_RS05450	COG0850	regulation of cytokinetic process
JH395_RS05455	COG2894	cell division
JH395_RS05460	COG0765	amino acid transport
JH395_RS05465	COG1126	abc transporter atp-binding protein
JH395_RS05470	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JH395_RS05475	COG0527	aspartate kinase activity
JH395_RS05480	COG0612	Peptidase, M16
JH395_RS05485	COG0612	Peptidase, M16
JH395_RS05490	COG1426	Protein conserved in bacteria
JH395_RS05495	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
JH395_RS05500	COG1058	Belongs to the CinA family
JH395_RS05500	COG1546	Belongs to the CinA family
JH395_RS05505	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
JH395_RS05510	COG1418	mRNA catabolic process
JH395_RS05515	COG1692	metallophosphoesterase
JH395_RS05520	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
JH395_RS05525	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
JH395_RS05545	COG0632	four-way junction helicase activity
JH395_RS05550	COG2255	four-way junction helicase activity
JH395_RS05555	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
JH395_RS05560	COG0343	queuine tRNA-ribosyltransferase activity
JH395_RS05565	COG1862	Preprotein translocase
JH395_RS05570	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
JH395_RS05575	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
JH395_RS05580	COG0513	Belongs to the DEAD box helicase family
JH395_RS05585	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
JH395_RS05590	COG4472	Bacterial protein of unknown function (DUF965)
JH395_RS05595	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
JH395_RS05600	COG3906	Belongs to the UPF0473 family
JH395_RS05610	COG1193	negative regulation of DNA recombination
JH395_RS05615	COG3118	belongs to the thioredoxin family
JH395_RS05620	COG1719	4-vinyl reductase, 4VR
JH395_RS05625	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
JH395_RS05630	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
JH395_RS05640	COG0517	IMP dehydrogenase activity
JH395_RS05645	COG2171	N-acyltransferase activity
JH395_RS05650	COG1473	amidohydrolase
JH395_RS05655	COG0668	transmembrane transport
JH395_RS05670	COG0789	Transcriptional regulator
JH395_RS05675	COG0006	proline dipeptidase activity
JH395_RS05680	COG1609	Transcriptional regulator
JH395_RS05695	COG0217	transcriptional regulatory protein
JH395_RS05705	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
JH395_RS05735	COG0827	DNA restriction-modification system
JH395_RS05740	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
JH395_RS05745	COG1113	amino acid transport
JH395_RS05755	COG0737	Belongs to the 5'-nucleotidase family
JH395_RS05760	COG4470	Protein conserved in bacteria
JH395_RS05765	COG0647	UMP catabolic process
JH395_RS05775	COG0586	Pfam SNARE associated Golgi protein
JH395_RS05785	COG1098	S1 RNA binding domain
JH395_RS05925	COG1234	tRNA 3'-trailer cleavage
JH395_RS05930	COG1393	Belongs to the ArsC family
JH395_RS05935	COG4862	establishment of competence for transformation
JH395_RS05945	COG1164	Oligoendopeptidase f
JH395_RS05955	COG2357	RelA SpoT domain protein
JH395_RS05960	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
JH395_RS05965	COG0564	pseudouridine synthase activity
JH395_RS05970	COG3142	Participates in the control of copper homeostasis
JH395_RS05975	COG2706	6-phosphogluconolactonase activity
JH395_RS05985	COG0628	permease
JH395_RS05990	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
JH395_RS06000	COG1114	Component of the transport system for branched-chain amino acids
JH395_RS06010	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
JH395_RS06015	COG1674	ftsk spoiiie
JH395_RS06035	COG2001	Belongs to the MraZ family
JH395_RS06040	COG0275	rRNA processing
JH395_RS06050	COG0768	penicillin binding
JH395_RS06055	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
JH395_RS06060	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
JH395_RS06065	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
JH395_RS06070	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
JH395_RS06085	COG1799	cell septum assembly
JH395_RS06090	COG0762	integral membrane protein
JH395_RS06100	COG3599	regulation of cell shape
JH395_RS06105	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
JH395_RS06120	COG3279	Response regulator of the LytR AlgR family
JH395_RS06130	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
JH395_RS06135	COG0494	nUDIX hydrolase
JH395_RS06145	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
JH395_RS06150	COG1104	cysteine desulfurase activity
JH395_RS06160	COG0482	sulfurtransferase activity
JH395_RS06165	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
JH395_RS06170	COG0569	domain protein
JH395_RS06200	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
JH395_RS06205	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
JH395_RS06210	COG3584	3D domain protein
JH395_RS06210	COG1388	LysM domain
JH395_RS06220	COG1597	lipid kinase activity
JH395_RS06225	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
JH395_RS06230	COG5503	Protein of unknown function (DUF1447)
JH395_RS06240	COG0242	peptide deformylase activity
JH395_RS06265	COG0039	L-malate dehydrogenase activity
JH395_RS06270	COG4476	Belongs to the UPF0223 family
JH395_RS06275	COG0483	inositol monophosphate 1-phosphatase activity
JH395_RS06280	COG1217	gtp-binding protein TYPA
JH395_RS06300	COG0772	Belongs to the SEDS family
JH395_RS06305	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
JH395_RS06310	COG4471	UPF0298 protein
JH395_RS06315	COG0742	ribosomal rna small subunit methyltransferase
JH395_RS06320	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
JH395_RS06325	COG3480	Lon protease (S16) C-terminal proteolytic domain
JH395_RS06330	COG1596	polysaccharide export
JH395_RS06330	COG1555	photosystem II stabilization
JH395_RS06335	COG2131	deaminase
JH395_RS06340	COG0658	competence protein
JH395_RS06340	COG2333	competence protein COMEC
JH395_RS06345	COG1466	dna polymerase III delta subunit
JH395_RS06350	COG0268	Binds directly to 16S ribosomal RNA
JH395_RS06355	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
JH395_RS06360	COG2826	transposase and inactivated derivatives, IS30 family
JH395_RS06385	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
JH395_RS06390	COG0544	peptidyl-prolyl cis-trans isomerase activity
JH395_RS06395	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
JH395_RS06400	COG0218	Necessary for normal cell division and for the maintenance of normal septation
JH395_RS06420	COG0765	amino acid transport
JH395_RS06425	COG1126	abc transporter atp-binding protein
JH395_RS06430	COG0322	excinuclease ABC activity
JH395_RS06440	COG0489	protein tyrosine kinase activity
JH395_RS06450	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
JH395_RS06455	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
JH395_RS06460	COG0297	glycogen (starch) synthase activity
JH395_RS06485	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
JH395_RS06490	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
JH395_RS06490	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JH395_RS06490	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JH395_RS06495	COG1105	Belongs to the carbohydrate kinase PfkB family
JH395_RS06500	COG1349	DNA-binding transcription factor activity
JH395_RS06505	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
JH395_RS06515	COG1234	tRNA 3'-trailer cleavage
JH395_RS06520	COG0300	oxidoreductase activity
JH395_RS06525	COG5416	Lipopolysaccharide assembly protein A domain
JH395_RS06530	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
JH395_RS06530	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
JH395_RS06535	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
JH395_RS06550	COG0393	Putative heavy-metal-binding
JH395_RS06615	COG0463	Glycosyl transferase, family 2
JH395_RS06630	COG3425	synthase
JH395_RS06645	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
JH395_RS06650	COG4224	UPF0291 protein
JH395_RS06655	COG3763	UPF0154 protein
JH395_RS06660	COG0204	Acyl-transferase
JH395_RS06665	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
JH395_RS06670	COG2827	Endonuclease containing a URI domain
JH395_RS06675	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
JH395_RS06685	COG0052	Belongs to the universal ribosomal protein uS2 family
JH395_RS06690	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
JH395_RS06695	COG0528	UMP kinase activity
JH395_RS06700	COG0233	cytoplasmic translational termination
JH395_RS06705	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
JH395_RS06710	COG4589	Belongs to the CDS family
JH395_RS06715	COG0750	zinc metalloprotease
JH395_RS06720	COG0442	prolyl-tRNA aminoacylation
JH395_RS06725	COG2176	DNA-directed DNA polymerase activity
JH395_RS06730	COG0779	Required for maturation of 30S ribosomal subunits
JH395_RS06735	COG0195	Participates in both transcription termination and antitermination
JH395_RS06740	COG2740	Nucleic-acid-binding protein implicated in transcription termination
JH395_RS06750	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
JH395_RS06755	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
JH395_RS06760	COG0738	Major facilitator superfamily
JH395_RS06765	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
JH395_RS06775	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
JH395_RS06780	COG0287	Prephenate dehydrogenase
JH395_RS06785	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
JH395_RS06790	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
JH395_RS06795	COG0196	riboflavin kinase activity
JH395_RS06800	COG3527	Alpha-acetolactate decarboxylase
JH395_RS06805	COG1420	regulation of RNA biosynthetic process
JH395_RS06810	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
JH395_RS06815	COG0443	Heat shock 70 kDa protein
JH395_RS06820	COG0484	heat shock protein binding
JH395_RS06825	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
JH395_RS06835	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
JH395_RS06840	COG1696	Membrane protein involved in D-alanine export
JH395_RS06845	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
JH395_RS06850	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
JH395_RS06855	COG0481	GTPase activity
JH395_RS06860	COG0582	viral genome integration into host DNA
JH395_RS06885	COG2094	Belongs to the DNA glycosylase MPG family
JH395_RS06890	COG2264	protein methyltransferase activity
JH395_RS06895	COG1385	rRNA (uridine-N3-)-methyltransferase activity
JH395_RS06905	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
JH395_RS06910	COG1490	D-aminoacyl-tRNA deacylase activity
JH395_RS06915	COG0546	phosphoglycolate phosphatase activity
JH395_RS06920	COG3001	Fructosamine kinase
JH395_RS06925	COG0860	N-Acetylmuramoyl-L-alanine amidase
JH395_RS06925	COG3103	Sh3 type 3 domain protein
JH395_RS06925	COG4991	sh3 domain protein
JH395_RS06930	COG0124	histidyl-tRNA synthetase
JH395_RS06935	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
JH395_RS06945	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
JH395_RS06955	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
JH395_RS06965	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
JH395_RS06970	COG0828	Belongs to the bacterial ribosomal protein bS21 family
JH395_RS06975	COG1610	YqeY-like protein
JH395_RS06980	COG1702	phosphate starvation-inducible protein PhoH
JH395_RS06985	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
JH395_RS06990	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
JH395_RS06995	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
JH395_RS07000	COG1381	Involved in DNA repair and RecF pathway recombination
JH395_RS07005	COG0752	glycyl-tRNA synthetase alpha subunit
JH395_RS07010	COG0751	glycine-tRNA ligase activity
JH395_RS07015	COG0358	DNA primase activity
JH395_RS07020	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
JH395_RS07025	COG1725	Transcriptional regulator
JH395_RS07030	COG1131	(ABC) transporter
JH395_RS07050	COG1131	(ABC) transporter
JH395_RS07065	COG0519	Catalyzes the synthesis of GMP from XMP
JH395_RS07075	COG1131	(ABC) transporter
JH395_RS07085	COG4585	Histidine kinase
JH395_RS07090	COG2197	response regulator
JH395_RS07095	COG0446	pyridine nucleotide-disulphide oxidoreductase
JH395_RS07105	COG0604	alcohol dehydrogenase
JH395_RS07110	COG0583	DNA-binding transcription factor activity
JH395_RS07140	COG0546	phosphoglycolate phosphatase activity
JH395_RS07160	COG1393	Belongs to the ArsC family
JH395_RS07170	COG1349	DNA-binding transcription factor activity
JH395_RS07175	COG0446	pyridine nucleotide-disulphide oxidoreductase
JH395_RS07180	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
JH395_RS07190	COG0477	Major facilitator Superfamily
JH395_RS07195	COG0148	phosphopyruvate hydratase activity
JH395_RS07200	COG2217	Heavy metal translocating P-type atpase
JH395_RS07220	COG1846	Transcriptional regulator
JH395_RS07230	COG0574	Belongs to the PEP-utilizing enzyme family
JH395_RS07230	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
JH395_RS07255	COG2384	SAM-dependent methyltransferase
JH395_RS07260	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
JH395_RS07270	COG0542	response to heat
JH395_RS07280	COG0587	DNA-directed DNA polymerase activity
JH395_RS07285	COG0205	6-phosphofructokinase activity
JH395_RS07300	COG2996	Protein conserved in bacteria
JH395_RS07305	COG4974	Belongs to the 'phage' integrase family
JH395_RS07315	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
JH395_RS07320	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
JH395_RS07325	COG1187	pseudouridine synthase activity
JH395_RS07330	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
JH395_RS07340	COG0514	ATP-dependent DNA helicase (RecQ)
JH395_RS07350	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
JH395_RS07355	COG0539	negative regulation of cytoplasmic translation
JH395_RS07360	COG1160	GTP binding
JH395_RS07370	COG0457	Tetratricopeptide repeat
JH395_RS07375	COG0561	phosphatase activity
JH395_RS07380	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
JH395_RS07385	COG0617	tRNA 3'-terminal CCA addition
JH395_RS07395	COG0488	(ABC) transporter
JH395_RS07400	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
JH395_RS07405	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
JH395_RS07410	COG1307	EDD domain protein, DegV family
JH395_RS07415	COG2755	lipolytic protein G-D-S-L family
JH395_RS07420	COG4698	Protein conserved in bacteria
JH395_RS07425	COG4479	Belongs to the UPF0346 family
JH395_RS07430	COG0793	Belongs to the peptidase S41A family
JH395_RS07430	COG3409	Peptidoglycan-binding domain 1 protein
JH395_RS07435	COG2814	Major facilitator Superfamily
JH395_RS07450	COG0583	DNA-binding transcription factor activity
JH395_RS07455	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
JH395_RS07460	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
JH395_RS07465	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
JH395_RS07470	COG0758	DNA mediated transformation
JH395_RS07475	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
JH395_RS07480	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
JH395_RS07485	COG4974	Belongs to the 'phage' integrase family
JH395_RS07490	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
JH395_RS07495	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
JH395_RS07505	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
JH395_RS07510	COG0187	DNA topoisomerase II activity
JH395_RS07520	COG0583	DNA-binding transcription factor activity
JH395_RS07525	COG1227	inorganic diphosphatase activity
JH395_RS07530	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
JH395_RS07570	COG1846	Transcriptional regulator
JH395_RS07595	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
JH395_RS07605	COG1620	l-lactate permease
JH395_RS07620	COG1113	amino acid transport
JH395_RS07675	COG1307	EDD domain protein, DegV family
JH395_RS07685	COG1293	RNA-binding protein homologous to eukaryotic snRNP
JH395_RS07690	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
JH395_RS07695	COG1131	(ABC) transporter
JH395_RS07720	COG5646	InterPro IPR014922
JH395_RS07735	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
JH395_RS07740	COG0505	Belongs to the CarA family
JH395_RS07745	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
JH395_RS07750	COG0564	pseudouridine synthase activity
JH395_RS07755	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
JH395_RS07760	COG2759	Belongs to the formate--tetrahydrofolate ligase family
JH395_RS07775	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
JH395_RS07800	COG1619	proteins homologs of microcin C7 resistance protein MccF
JH395_RS07820	COG1216	Glycosyl transferase, family 2
JH395_RS07830	COG1073	alpha beta
JH395_RS07835	COG0477	Major facilitator Superfamily
JH395_RS07845	COG0116	Belongs to the methyltransferase superfamily
JH395_RS07855	COG3599	regulation of cell shape
JH395_RS07860	COG4474	Belongs to the UPF0398 family
JH395_RS07865	COG3331	DNA recombination
JH395_RS07880	COG1840	ABC-type Fe3 transport system, periplasmic component
JH395_RS07885	COG1177	transmembrane transport
JH395_RS07895	COG1464	Belongs to the NlpA lipoprotein family
JH395_RS07900	COG2011	ABC-type metal ion transport system permease component
JH395_RS07905	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
JH395_RS07915	COG0017	Asparaginyl-tRNA synthetase
JH395_RS07930	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
JH395_RS07930	COG1199	ATP-dependent helicase activity
JH395_RS07950	COG1304	FMN binding
JH395_RS07955	COG2017	converts alpha-aldose to the beta-anomer
JH395_RS07975	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
JH395_RS07975	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
JH395_RS07980	COG0561	phosphatase activity
JH395_RS07985	COG0531	amino acid
JH395_RS08020	COG1942	4-Oxalocrotonate Tautomerase
JH395_RS08035	COG3237	CsbD-like
JH395_RS08040	COG2261	transglycosylase associated protein
JH395_RS08050	COG1597	lipid kinase activity
JH395_RS08055	COG3152	Membrane
JH395_RS08065	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
JH395_RS08080	COG3397	chitin binding
JH395_RS08085	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
JH395_RS08135	COG0477	Major facilitator Superfamily
JH395_RS08145	COG1162	GTPase activity
JH395_RS08150	COG1607	acyl-coa hydrolase
JH395_RS08155	COG0583	DNA-binding transcription factor activity
JH395_RS08160	COG1811	Na channel or pump
JH395_RS08170	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
JH395_RS08185	COG0439	Biotin carboxylase
JH395_RS08200	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
JH395_RS08205	COG1028	Short-chain dehydrogenase reductase Sdr
JH395_RS08210	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
JH395_RS08215	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
JH395_RS08220	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
JH395_RS08225	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
JH395_RS08235	COG0300	oxidoreductase activity
JH395_RS08245	COG1063	alcohol dehydrogenase
JH395_RS08260	COG0159	tryptophan synthase activity
JH395_RS08265	COG0133	tryptophan synthase activity
JH395_RS08270	COG0135	phosphoribosylanthranilate isomerase activity
JH395_RS08275	COG0134	indole-3-glycerol-phosphate synthase activity
JH395_RS08280	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
JH395_RS08285	COG0512	Glutamine amidotransferase of anthranilate synthase
JH395_RS08285	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
JH395_RS08320	COG0335	large ribosomal subunit rRNA binding
JH395_RS08325	COG0336	Belongs to the RNA methyltransferase TrmD family
JH395_RS08330	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
JH395_RS08335	COG1837	Belongs to the UPF0109 family
JH395_RS08340	COG0228	four-way junction DNA binding
JH395_RS08345	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
JH395_RS08350	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
JH395_RS08355	COG0552	protein localization to endoplasmic reticulum
JH395_RS08360	COG1196	nuclear chromosome segregation
JH395_RS08365	COG0571	ribonuclease III activity
JH395_RS08370	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
JH395_RS08375	COG0416	fatty acid biosynthetic process
JH395_RS08380	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
JH395_RS08385	COG1461	Dihydroxyacetone kinase
JH395_RS08390	COG1302	Protein conserved in bacteria
JH395_RS08395	COG0227	Belongs to the bacterial ribosomal protein bL28 family
JH395_RS08405	COG1564	THIamine pyrophosphokinase
JH395_RS08410	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
JH395_RS08415	COG1162	GTPase activity
JH395_RS08420	COG2815	serine threonine protein kinase
JH395_RS08420	COG0515	serine threonine protein kinase
JH395_RS08425	COG0631	protein serine/threonine phosphatase activity
JH395_RS08430	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
JH395_RS08430	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
JH395_RS08435	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
JH395_RS08440	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
JH395_RS08445	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
JH395_RS08450	COG1758	RNA polymerase activity
JH395_RS08455	COG0194	GDP metabolic process
JH395_RS08470	COG1732	Glycine betaine
JH395_RS08485	COG0497	DNA recombination
JH395_RS08490	COG1438	arginine binding
JH395_RS08495	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
JH395_RS08500	COG0142	geranyltranstransferase activity
JH395_RS08505	COG1722	exodeoxyribonuclease VII activity
JH395_RS08510	COG1570	exodeoxyribonuclease VII activity
JH395_RS08515	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
JH395_RS08520	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
JH395_RS08525	COG1302	Protein conserved in bacteria
JH395_RS08530	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
JH395_RS08535	COG0006	proline dipeptidase activity
JH395_RS08540	COG0211	Belongs to the bacterial ribosomal protein bL27 family
JH395_RS08550	COG0261	This protein binds to 23S rRNA in the presence of protein L20
JH395_RS08565	COG2826	transposase and inactivated derivatives, IS30 family
JH395_RS08610	COG0789	Transcriptional regulator
JH395_RS08615	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
JH395_RS08620	COG0584	glycerophosphoryl diester phosphodiesterase
JH395_RS08640	COG1940	carbohydrate kinase activity
JH395_RS08650	COG0705	Rhomboid family
JH395_RS08650	COG0457	Tetratricopeptide repeat
JH395_RS08655	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
JH395_RS08660	COG0267	Belongs to the bacterial ribosomal protein bL33 family
JH395_RS08665	COG0768	penicillin binding
JH395_RS08675	COG4841	protein insertion into membrane
JH395_RS08690	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
JH395_RS08695	COG0572	uridine kinase
JH395_RS08700	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
JH395_RS08705	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
JH395_RS08705	COG0072	phenylalanine-tRNA ligase activity
JH395_RS08710	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
JH395_RS08715	COG1733	regulation of RNA biosynthetic process
JH395_RS08725	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
JH395_RS08730	COG1254	Belongs to the acylphosphatase family
JH395_RS08735	COG0706	membrane insertase activity
JH395_RS08750	COG0419	ATPase involved in DNA repair
JH395_RS08760	COG5002	protein histidine kinase activity
JH395_RS08765	COG0745	RESPONSE REGULATOR receiver
JH395_RS08770	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
JH395_RS08775	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
JH395_RS08790	COG0333	Belongs to the bacterial ribosomal protein bL32 family
JH395_RS08800	COG1323	Belongs to the UPF0348 family
JH395_RS08805	COG2226	methyltransferase
JH395_RS08810	COG0799	negative regulation of ribosome biogenesis
JH395_RS08815	COG1713	HD superfamily hydrolase involved in NAD metabolism
JH395_RS08820	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
JH395_RS08825	COG1534	Rna-binding protein
JH395_RS08830	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
JH395_RS08845	COG1215	transferase activity, transferring glycosyl groups
JH395_RS08855	COG1733	regulation of RNA biosynthetic process
JH395_RS08860	COG0604	alcohol dehydrogenase
JH395_RS08865	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
JH395_RS08875	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
JH395_RS08880	COG0291	Belongs to the bacterial ribosomal protein bL35 family
JH395_RS08885	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
JH395_RS08890	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
JH395_RS08895	COG1484	DNA-dependent DNA replication
JH395_RS08900	COG3611	Membrane attachment protein
JH395_RS08905	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
JH395_RS08910	COG0237	dephospho-CoA kinase activity
JH395_RS08915	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
JH395_RS08920	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
JH395_RS08920	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
JH395_RS08935	COG2151	metal-sulfur cluster biosynthetic enzyme
JH395_RS08940	COG0719	Fe-S assembly protein
JH395_RS08950	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
JH395_RS08955	COG0719	Fe-S assembly protein
JH395_RS08980	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
JH395_RS08985	COG1674	ftsk spoiiie
JH395_RS08990	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
JH395_RS09000	COG0220	tRNA (guanine-N7-)-methyltransferase activity
JH395_RS09005	COG0510	thiamine kinase activity
JH395_RS09010	COG4473	ABC transporter
JH395_RS09015	COG1131	(ABC) transporter
JH395_RS09020	COG0537	adenosine 5'-monophosphoramidase activity
JH395_RS09030	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
JH395_RS09060	COG0446	pyridine nucleotide-disulphide oxidoreductase
JH395_RS09070	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
JH395_RS09090	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
JH395_RS09095	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
JH395_RS09095	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
JH395_RS09100	COG0307	riboflavin synthase, alpha
JH395_RS09105	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
JH395_RS09105	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
JH395_RS09125	COG0463	Glycosyl transferase, family 2
JH395_RS09140	COG1053	succinate dehydrogenase
JH395_RS09140	COG0431	NADPH-dependent FMN reductase
JH395_RS09140	COG3976	FMN-binding domain protein
JH395_RS09150	COG0583	DNA-binding transcription factor activity
JH395_RS09165	COG3481	metal-dependent phosphohydrolase, HD sub domain
JH395_RS09170	COG4717	serine-type aminopeptidase activity
JH395_RS09175	COG0420	3'-5' exonuclease activity
JH395_RS09180	COG3679	Belongs to the UPF0342 family
JH395_RS09185	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
JH395_RS09190	COG1438	arginine binding
JH395_RS09195	COG0436	Aminotransferase
JH395_RS09205	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
JH395_RS09210	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
JH395_RS09215	COG1376	ErfK ybiS ycfS ynhG family protein
JH395_RS09225	COG2723	6-phospho-beta-galactosidase activity
JH395_RS09230	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
JH395_RS09235	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
JH395_RS09240	COG1447	Phosphotransferase system cellobiose-specific component IIA
JH395_RS09260	COG0577	efflux transmembrane transporter activity
JH395_RS09260	COG1136	(ABC) transporter
JH395_RS09270	COG0018	arginyl-trna synthetase
JH395_RS09275	COG2153	protein acetylation
JH395_RS09295	COG0534	Mate efflux family protein
JH395_RS09300	COG3273	potassium ion transport
JH395_RS09300	COG0471	metal ion transport
JH395_RS09310	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
JH395_RS09315	COG0529	Catalyzes the synthesis of activated sulfate
JH395_RS09320	COG2046	Belongs to the sulfate adenylyltransferase family
JH395_RS09330	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
JH395_RS09335	COG0646	methionine synthase
JH395_RS09335	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
JH395_RS09535	COG1484	DNA-dependent DNA replication
JH395_RS09605	COG3646	Phage regulatory protein
JH395_RS09620	COG1396	sequence-specific DNA binding
JH395_RS09665	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
JH395_RS09680	COG1846	Transcriptional regulator
JH395_RS09700	COG3279	Response regulator of the LytR AlgR family
JH395_RS09715	COG0561	phosphatase activity
JH395_RS09730	COG0789	Transcriptional regulator
JH395_RS09735	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
JH395_RS09765	COG1511	domain protein
JH395_RS09765	COG1511	domain protein
JH395_RS09770	COG1970	mechanosensitive ion channel activity
JH395_RS09775	COG1428	Deoxynucleoside kinase
JH395_RS09780	COG0584	glycerophosphoryl diester phosphodiesterase
JH395_RS09790	COG0395	ABC-type sugar transport system, permease component
JH395_RS09795	COG1175	transmembrane transport
JH395_RS09800	COG3842	ATPase activity
JH395_RS09810	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
JH395_RS09815	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
JH395_RS09820	COG1187	pseudouridine synthase activity
JH395_RS09825	COG2244	polysaccharide biosynthetic process
JH395_RS09830	COG0495	leucyl-tRNA aminoacylation
JH395_RS09840	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
JH395_RS09855	COG0438	transferase activity, transferring glycosyl groups
JH395_RS09870	COG0477	Major facilitator Superfamily
JH395_RS09875	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
JH395_RS09885	COG0438	transferase activity, transferring glycosyl groups
JH395_RS09890	COG2040	homocysteine
JH395_RS09895	COG0833	amino acid
JH395_RS09900	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
JH395_RS09910	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
JH395_RS09930	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
JH395_RS10015	COG1368	sulfuric ester hydrolase activity
JH395_RS10020	COG4703	Protein of unknown function (DUF1797)
JH395_RS10025	COG0436	Aminotransferase
JH395_RS10030	COG1686	Belongs to the peptidase S11 family
JH395_RS10040	COG0438	transferase activity, transferring glycosyl groups
JH395_RS10045	COG0438	transferase activity, transferring glycosyl groups
JH395_RS10065	COG0542	response to heat
JH395_RS10070	COG0582	viral genome integration into host DNA
JH395_RS10080	COG4608	Belongs to the ABC transporter superfamily
JH395_RS10085	COG0444	Belongs to the ABC transporter superfamily
JH395_RS10090	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
JH395_RS10095	COG0601	transmembrane transport
JH395_RS10100	COG4166	transmembrane transport
JH395_RS10130	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
JH395_RS10135	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
JH395_RS10140	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
JH395_RS10145	COG1070	Carbohydrate kinase
JH395_RS10150	COG2610	gluconate transmembrane transporter activity
JH395_RS10155	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
JH395_RS10160	COG0628	permease
JH395_RS10170	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
JH395_RS10190	COG3557	Belongs to the UPF0374 family
JH395_RS10195	COG2137	regulation of response to DNA damage stimulus
JH395_RS10230	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
JH395_RS10260	COG1091	dTDP-4-dehydrorhamnose reductase activity
JH395_RS10265	COG1088	dTDP-glucose 4,6-dehydratase activity
JH395_RS10275	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
JH395_RS10305	COG0110	maltose O-acetyltransferase activity
JH395_RS10310	COG1215	transferase activity, transferring glycosyl groups
JH395_RS10310	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
JH395_RS10340	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
JH395_RS10350	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
JH395_RS10360	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
JH395_RS10385	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
JH395_RS10400	COG0513	Belongs to the DEAD box helicase family
JH395_RS10405	COG0673	inositol 2-dehydrogenase activity
JH395_RS10410	COG1278	Cold shock
JH395_RS10425	COG1737	Transcriptional regulator
JH395_RS10435	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
JH395_RS10450	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
JH395_RS10455	COG1597	lipid kinase activity
JH395_RS10460	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
JH395_RS10465	COG0154	amidase activity
JH395_RS10470	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
JH395_RS10475	COG4851	CamS sex pheromone cAM373 precursor
JH395_RS10480	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
JH395_RS10490	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
JH395_RS10495	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
JH395_RS10500	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
JH395_RS10505	COG1705	Flagellar rod assembly protein muramidase FlgJ
JH395_RS10520	COG0142	geranyltranstransferase activity
JH395_RS10530	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
JH395_RS10535	COG4988	ABC transporter
JH395_RS10540	COG1294	oxidase, subunit
JH395_RS10545	COG1271	oxidase subunit
JH395_RS10565	COG0531	amino acid
JH395_RS10575	COG0281	malic enzyme
JH395_RS10580	COG0583	DNA-binding transcription factor activity
JH395_RS10595	COG1053	succinate dehydrogenase
JH395_RS10600	COG0114	fumarate hydratase activity
JH395_RS10630	COG3052	prosthetic group binding
JH395_RS10650	COG0471	metal ion transport
JH395_RS10655	COG0039	L-malate dehydrogenase activity
JH395_RS10665	COG0803	Belongs to the bacterial solute-binding protein 9 family
JH395_RS10670	COG1108	ABC-type Mn2 Zn2 transport systems permease components
JH395_RS10675	COG1121	(ABC) transporter
JH395_RS10680	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
JH395_RS10685	COG1917	Cupin 2, conserved barrel domain protein
JH395_RS10685	COG4977	sequence-specific DNA binding
JH395_RS10695	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
JH395_RS10700	COG2151	metal-sulfur cluster biosynthetic enzyme
JH395_RS10705	COG0471	metal ion transport
JH395_RS10710	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
JH395_RS10715	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
JH395_RS10720	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
JH395_RS10725	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
JH395_RS10745	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
JH395_RS10750	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
JH395_RS10755	COG0101	tRNA pseudouridine synthase activity
JH395_RS10765	COG1122	ATPase activity
JH395_RS10770	COG1122	ATPase activity
JH395_RS10780	COG4939	FMN-binding domain protein
JH395_RS10805	COG0203	ribosomal protein L17
JH395_RS10810	COG0202	RNA polymerase activity
JH395_RS10815	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
JH395_RS10820	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
JH395_RS10825	COG0257	Belongs to the bacterial ribosomal protein bL36 family
JH395_RS10830	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
JH395_RS10835	COG0563	adenylate kinase activity
JH395_RS10845	COG0200	Binds to the 23S rRNA
JH395_RS10850	COG1841	ribosomal large subunit assembly
JH395_RS10855	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
JH395_RS10860	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
JH395_RS10865	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
JH395_RS10870	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
JH395_RS10875	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
JH395_RS10880	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
JH395_RS10885	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
JH395_RS10890	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
JH395_RS10895	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
JH395_RS10900	COG0255	Belongs to the universal ribosomal protein uL29 family
JH395_RS10905	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
JH395_RS10910	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
JH395_RS10915	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
JH395_RS10920	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
JH395_RS10925	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
JH395_RS10930	COG0089	rRNA binding
JH395_RS10935	COG0088	Forms part of the polypeptide exit tunnel
JH395_RS10940	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
JH395_RS10945	COG0051	transcription antitermination factor activity, RNA binding
JH395_RS10950	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
JH395_RS10955	COG0049	tRNA binding
JH395_RS10960	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
JH395_RS10965	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
JH395_RS10970	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
JH395_RS10975	COG0085	RNA polymerase activity
JH395_RS10985	COG0542	response to heat
JH395_RS10990	COG4463	regulation of RNA biosynthetic process
JH395_RS11030	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
JH395_RS11035	COG1428	Deoxynucleoside kinase
JH395_RS11045	COG0833	amino acid
JH395_RS11050	COG0028	Belongs to the TPP enzyme family
JH395_RS11055	COG1959	2 iron, 2 sulfur cluster binding
JH395_RS11075	COG1316	TRANSCRIPTIONal
JH395_RS11085	COG2966	Psort location CytoplasmicMembrane, score
JH395_RS11090	COG1278	Cold shock
JH395_RS11110	COG2814	Major facilitator Superfamily
JH395_RS11140	COG0367	asparagine synthase
JH395_RS11145	COG0527	aspartate kinase activity
JH395_RS11150	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
JH395_RS11200	COG0640	Transcriptional regulator
JH395_RS11205	COG0564	pseudouridine synthase activity
JH395_RS11210	COG0514	ATP-dependent DNA helicase (RecQ)
JH395_RS11230	COG4690	dipeptidase activity
JH395_RS11235	COG2502	aspartate--ammonia ligase
JH395_RS11240	COG0017	Asparaginyl-tRNA synthetase
JH395_RS11245	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
JH395_RS11255	COG1053	succinate dehydrogenase
JH395_RS11260	COG0583	DNA-binding transcription factor activity
JH395_RS11275	COG0572	uridine kinase
JH395_RS11305	COG0308	aminopeptidase N
JH395_RS11335	COG1302	Protein conserved in bacteria
JH395_RS11350	COG2261	transglycosylase associated protein
JH395_RS11355	COG2755	lipolytic protein G-D-S-L family
JH395_RS11355	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
JH395_RS11370	COG2814	Major facilitator Superfamily
JH395_RS11375	COG1733	regulation of RNA biosynthetic process
JH395_RS11380	COG1266	CAAX protease self-immunity
JH395_RS11390	COG1396	sequence-specific DNA binding
JH395_RS11400	COG0518	GMP synthase (glutamine-hydrolyzing) activity
JH395_RS11400	COG0519	Catalyzes the synthesis of GMP from XMP
JH395_RS11405	COG1072	(Pantothenic acid kinase))
JH395_RS11410	COG2070	2-Nitropropane dioxygenase
JH395_RS11415	COG3973	AAA domain
JH395_RS11420	COG0586	Pfam SNARE associated Golgi protein
JH395_RS11425	COG0456	acetyltransferase
JH395_RS11425	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
JH395_RS11430	COG0475	glutathione-regulated potassium exporter activity
JH395_RS11430	COG0569	domain protein
JH395_RS11435	COG0588	phosphoglycerate mutase activity
JH395_RS11450	COG2076	Multidrug Resistance protein
JH395_RS11460	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
JH395_RS11490	COG1846	Transcriptional regulator
JH395_RS11495	COG0531	amino acid
JH395_RS11500	COG3394	polysaccharide catabolic process
JH395_RS11505	COG1263	PTS System
JH395_RS11505	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JH395_RS11515	COG2190	(PTS) system
JH395_RS11515	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JH395_RS11515	COG1263	PTS System
JH395_RS11520	COG0765	amino acid transport
JH395_RS11525	COG0765	amino acid transport
JH395_RS11530	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JH395_RS11545	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
JH395_RS11550	COG0436	Aminotransferase
JH395_RS11555	COG0546	phosphoglycolate phosphatase activity
JH395_RS11570	COG0735	belongs to the Fur family
JH395_RS11575	COG0194	GDP metabolic process
JH395_RS11600	COG0531	amino acid
JH395_RS11615	COG2936	dipeptidyl-peptidase activity
JH395_RS11620	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
JH395_RS11620	COG2755	lipolytic protein G-D-S-L family
JH395_RS11630	COG2267	carboxylic ester hydrolase activity
JH395_RS11635	COG0028	Belongs to the TPP enzyme family
JH395_RS11640	COG0196	riboflavin kinase activity
JH395_RS11645	COG0028	Belongs to the TPP enzyme family
JH395_RS11650	COG2252	PERMEase
JH395_RS11665	COG3475	LICD family
JH395_RS11675	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
JH395_RS11680	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
JH395_RS11680	COG0248	Ppx GppA phosphatase
JH395_RS11685	COG0477	Major facilitator Superfamily
JH395_RS11700	COG1393	Belongs to the ArsC family
JH395_RS11715	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
JH395_RS11730	COG0778	Nitroreductase
JH395_RS11745	COG2017	converts alpha-aldose to the beta-anomer
JH395_RS11755	COG0561	phosphatase activity
JH395_RS11765	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
JH395_RS11770	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
JH395_RS11795	COG0025	NhaP-type Na H and K H
JH395_RS11800	COG0812	UDP-N-acetylmuramate dehydrogenase activity
JH395_RS11810	COG0708	Exodeoxyribonuclease III
JH395_RS11825	COG0802	atpase or kinase
JH395_RS11830	COG0280	phosphate acetyltransferase
JH395_RS11835	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
JH395_RS11840	COG0561	phosphatase activity
JH395_RS11850	COG1126	abc transporter atp-binding protein
JH395_RS11855	COG0765	amino acid transport
JH395_RS11865	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
JH395_RS11870	COG0557	exoribonuclease II activity
JH395_RS11880	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
JH395_RS11885	COG0038	chloride channel
JH395_RS11895	COG0148	phosphopyruvate hydratase activity
JH395_RS11900	COG0149	triose-phosphate isomerase activity
JH395_RS11905	COG0126	phosphoglycerate kinase activity
JH395_RS11915	COG2390	Transcriptional regulator
JH395_RS11920	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
JH395_RS11930	COG0740	serine-type endopeptidase activity
JH395_RS11935	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
JH395_RS11940	COG4166	transmembrane transport
JH395_RS11945	COG1481	regulation of sporulation
JH395_RS11955	COG1660	Displays ATPase and GTPase activities
JH395_RS11965	COG0165	Argininosuccinate lyase
JH395_RS11970	COG0137	argininosuccinate synthase activity
JH395_RS11975	COG1854	S-ribosylhomocysteine lyase activity
JH395_RS11980	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
JH395_RS11985	COG0556	nucleotide-excision repair
JH395_RS11995	COG2814	Major facilitator Superfamily
JH395_RS12015	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
JH395_RS12025	COG2323	membrane
JH395_RS12030	COG0492	ferredoxin-NADP+ reductase activity
JH395_RS12045	COG1215	transferase activity, transferring glycosyl groups
JH395_RS12065	COG0446	pyridine nucleotide-disulphide oxidoreductase
JH395_RS12075	COG1210	Utp--glucose-1-phosphate uridylyltransferase
JH395_RS12080	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
JH395_RS12085	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
JH395_RS12090	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
JH395_RS12095	COG1950	PFAM Membrane protein of
JH395_RS12100	COG1983	PspC domain protein
JH395_RS12105	COG0704	Plays a role in the regulation of phosphate uptake
JH395_RS12110	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
JH395_RS12115	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
JH395_RS12120	COG0581	inorganic phosphate transmembrane transporter activity
JH395_RS12125	COG0573	inorganic phosphate transmembrane transporter activity
JH395_RS12130	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
JH395_RS12135	COG5002	protein histidine kinase activity
JH395_RS12140	COG0745	RESPONSE REGULATOR receiver
JH395_RS12155	COG0653	protein targeting
JH395_RS12170	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
JH395_RS12175	COG1739	Uncharacterized protein family UPF0029
JH395_RS12180	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
JH395_RS12185	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
JH395_RS12190	COG0531	amino acid
JH395_RS12195	COG0459	protein refolding
JH395_RS12200	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
JH395_RS12210	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
JH395_RS12215	COG0488	(ABC) transporter
JH395_RS12220	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
JH395_RS12225	COG0456	acetyltransferase
JH395_RS12230	COG0456	acetyltransferase
JH395_RS12235	COG1214	PFAM Peptidase M22, glycoprotease
JH395_RS12245	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
JH395_RS12255	COG3639	organic phosphonate transmembrane transporter activity
JH395_RS12260	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
JH395_RS12265	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
JH395_RS12270	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
JH395_RS12285	COG4467	Involved in initiation control of chromosome replication
JH395_RS12290	COG0470	DNA polymerase III
JH395_RS12295	COG3870	Protein conserved in bacteria
JH395_RS12300	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
JH395_RS12310	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
JH395_RS12315	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
JH395_RS12320	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
JH395_RS12335	COG2813	Specifically methylates the guanine in position
JH395_RS12340	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
JH395_RS12345	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
JH395_RS12355	COG1611	Belongs to the LOG family
JH395_RS12375	COG0222	ribosome binding
JH395_RS12380	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
JH395_RS12385	COG0081	regulation of translation
JH395_RS12390	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
JH395_RS12400	COG0250	Participates in transcription elongation, termination and antitermination
JH395_RS12410	COG0267	Belongs to the bacterial ribosomal protein bL33 family
JH395_RS12425	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
JH395_RS12430	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
JH395_RS12435	COG0215	cysteine-tRNA ligase activity
JH395_RS12440	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
JH395_RS12445	COG4956	integral membrane protein (PIN domain superfamily)
JH395_RS12455	COG0756	dUTP diphosphatase activity
JH395_RS12465	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
JH395_RS12480	COG0588	phosphoglycerate mutase activity
JH395_RS12485	COG0697	spore germination
JH395_RS12495	COG1316	TRANSCRIPTIONal
JH395_RS12500	COG0825	malonyl-CoA metabolic process
JH395_RS12510	COG0439	Biotin carboxylase
JH395_RS12520	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
JH395_RS12525	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JH395_RS12525	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
JH395_RS12530	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
JH395_RS12530	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JH395_RS12535	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
JH395_RS12535	COG3933	PFAM sigma-54 factor interaction domain-containing protein
JH395_RS12565	COG1713	HD superfamily hydrolase involved in NAD metabolism
JH395_RS12570	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
JH395_RS12580	COG3716	PTS system mannose fructose sorbose family IID component
JH395_RS12585	COG3715	PTS system
JH395_RS12865	COG1396	sequence-specific DNA binding
JH395_RS12915	COG0083	homoserine kinase activity
JH395_RS12920	COG0460	homoserine dehydrogenase
JH395_RS12925	COG3091	SprT-like family
JH395_RS12930	COG2183	response to ionizing radiation
JH395_RS12945	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
JH395_RS12950	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
JH395_RS12960	COG2188	Transcriptional regulator
JH395_RS12970	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
JH395_RS13020	COG3104	oligopeptide transport
JH395_RS13060	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
JH395_RS13065	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
JH395_RS13070	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
JH395_RS13085	COG0037	tRNA processing
JH395_RS13090	COG1098	S1 RNA binding domain
JH395_RS13100	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
JH395_RS13105	COG2244	polysaccharide biosynthetic process
JH395_RS13110	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
JH395_RS13115	COG0193	aminoacyl-tRNA hydrolase activity
JH395_RS13120	COG0039	L-malate dehydrogenase activity
JH395_RS13135	COG2267	carboxylic ester hydrolase activity
JH395_RS13150	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
JH395_RS13155	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
JH395_RS13160	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
JH395_RS13165	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
JH395_RS13170	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
JH395_RS13175	COG0505	Belongs to the CarA family
JH395_RS13180	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
JH395_RS13200	COG3158	transport of potassium into the cell
JH395_RS13205	COG2337	Toxic component of a toxin-antitoxin (TA) module
JH395_RS13210	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
JH395_RS13215	COG0736	holo-[acyl-carrier-protein] synthase activity
JH395_RS13225	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
JH395_RS13235	COG0501	Belongs to the peptidase M48B family
JH395_RS13240	COG1704	LemA family
JH395_RS13245	COG3764	Sortase (surface protein transpeptidase)
JH395_RS13255	COG0254	rRNA binding
JH395_RS13260	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
JH395_RS13265	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
JH395_RS13280	COG1760	l-serine dehydratase
JH395_RS13285	COG1760	l-serine dehydratase
JH395_RS13290	COG0814	amino acid
JH395_RS13295	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
JH395_RS13300	COG0504	CTP synthase activity
JH395_RS13305	COG3343	RNA polymerase activity
JH395_RS13315	COG0095	Lipoate-protein ligase
JH395_RS13320	COG1078	dGTPase activity
JH395_RS13340	COG2826	transposase and inactivated derivatives, IS30 family
JH395_RS13345	COG1380	Effector of murein hydrolase LrgA
JH395_RS13355	COG1307	EDD domain protein, DegV family
JH395_RS13365	COG2738	Putative neutral zinc metallopeptidase
JH395_RS13370	COG1233	COG1233 Phytoene dehydrogenase and related
JH395_RS13375	COG1562	ergosterol biosynthetic process
JH395_RS13385	COG1929	Belongs to the glycerate kinase type-1 family
JH395_RS13400	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
JH395_RS13405	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
JH395_RS13410	COG0516	GMP reductase activity
JH395_RS13415	COG2365	Tyrosine phosphatase family
JH395_RS13420	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
JH395_RS13435	COG0531	amino acid
JH395_RS13440	COG3158	transport of potassium into the cell
JH395_RS13445	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
JH395_RS13450	COG0628	permease
JH395_RS13455	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
JH395_RS13470	COG1272	protein, Hemolysin III
JH395_RS13475	COG0640	Transcriptional regulator
JH395_RS13510	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
JH395_RS13520	COG0302	gtp cyclohydrolase
JH395_RS13525	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
JH395_RS13540	COG0803	Belongs to the bacterial solute-binding protein 9 family
JH395_RS13550	COG2814	Major facilitator Superfamily
JH395_RS13580	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
JH395_RS13585	COG1882	Formate acetyltransferase
JH395_RS13590	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
JH395_RS13595	COG2151	metal-sulfur cluster biosynthetic enzyme
JH395_RS13600	COG4989	oxidoreductase activity
JH395_RS13630	COG2217	Heavy metal translocating P-type atpase
JH395_RS13640	COG2315	Protein conserved in bacteria
JH395_RS13650	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
JH395_RS13655	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
JH395_RS13670	COG1757	Na H antiporter
JH395_RS13675	COG1113	amino acid transport
JH395_RS13685	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
JH395_RS13700	COG1393	Belongs to the ArsC family
JH395_RS13705	COG3189	MarR family transcriptional regulator
JH395_RS13715	COG1194	a g-specific adenine glycosylase
JH395_RS13730	COG0071	Belongs to the small heat shock protein (HSP20) family
JH395_RS13755	COG0697	spore germination
JH395_RS13770	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
JH395_RS13795	COG0477	Major facilitator Superfamily
JH395_RS13850	COG0737	Belongs to the 5'-nucleotidase family
JH395_RS13860	COG0656	L-ascorbic acid biosynthetic process
JH395_RS13880	COG1968	undecaprenyl-diphosphatase activity
JH395_RS13885	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
JH395_RS13920	COG2207	Transcriptional regulator
JH395_RS13945	COG0076	glutamate decarboxylase activity
JH395_RS13985	COG1309	transcriptional regulator
JH395_RS13995	COG2226	methyltransferase
JH395_RS14010	COG2217	Heavy metal translocating P-type atpase
JH395_RS14015	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
JH395_RS14020	COG3118	belongs to the thioredoxin family
JH395_RS14025	COG1937	Protein conserved in bacteria
JH395_RS14045	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
JH395_RS14050	COG3590	peptidase
JH395_RS14065	COG0446	pyridine nucleotide-disulphide oxidoreductase
JH395_RS14115	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
JH395_RS14125	COG1114	Component of the transport system for branched-chain amino acids
JH395_RS14135	COG1874	Beta-galactosidase
JH395_RS14140	COG1609	Transcriptional regulator
JH395_RS14150	COG0477	Major facilitator Superfamily
JH395_RS14175	COG2184	nucleotidyltransferase activity
JH395_RS14185	COG1609	Transcriptional regulator
JH395_RS14190	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
JH395_RS14195	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
JH395_RS14200	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
JH395_RS14220	COG2211	Major facilitator Superfamily
JH395_RS14220	COG2190	(PTS) system
JH395_RS14225	COG2017	converts alpha-aldose to the beta-anomer
JH395_RS14230	COG1609	Transcriptional regulator
JH395_RS14235	COG0667	Aldo Keto reductase
JH395_RS14255	COG0710	3-dehydroquinate dehydratase activity
JH395_RS14260	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
JH395_RS14265	COG0583	DNA-binding transcription factor activity
JH395_RS14270	COG2271	Major facilitator Superfamily
JH395_RS14285	COG1028	Short-chain dehydrogenase reductase Sdr
JH395_RS14300	COG2271	Major facilitator Superfamily
JH395_RS14310	COG2267	carboxylic ester hydrolase activity
JH395_RS14315	COG2188	Transcriptional regulator
JH395_RS14320	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
JH395_RS14325	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
JH395_RS14330	COG2971	BadF BadG BcrA BcrD
JH395_RS14340	COG2723	6-phospho-beta-galactosidase activity
JH395_RS14350	COG3711	transcriptional antiterminator
JH395_RS14360	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
JH395_RS14365	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JH395_RS14365	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JH395_RS14370	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
JH395_RS14370	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JH395_RS14370	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JH395_RS14375	COG2190	(PTS) system
JH395_RS14375	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JH395_RS14375	COG1263	PTS System
JH395_RS14380	COG1737	Transcriptional regulator
JH395_RS14385	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JH395_RS14385	COG1263	PTS System
JH395_RS14390	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
JH395_RS14400	COG2723	6-phospho-beta-galactosidase activity
JH395_RS14405	COG2723	6-phospho-beta-galactosidase activity
JH395_RS14410	COG1263	PTS System
JH395_RS14410	COG2190	(PTS) system
JH395_RS14410	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JH395_RS14430	COG2211	Major facilitator Superfamily
JH395_RS14445	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
JH395_RS14460	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
JH395_RS14465	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
JH395_RS14470	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JH395_RS14470	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
JH395_RS14470	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JH395_RS14475	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JH395_RS14490	COG3711	transcriptional antiterminator
JH395_RS14500	COG3775	system Galactitol-specific IIC component
JH395_RS14505	COG3414	Phosphotransferase system galactitol-specific IIB component
JH395_RS14515	COG1349	DNA-binding transcription factor activity
JH395_RS14520	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
JH395_RS14530	COG0110	maltose O-acetyltransferase activity
JH395_RS14535	COG2160	L-arabinose isomerase activity
JH395_RS14555	COG1609	Transcriptional regulator
JH395_RS14560	COG1737	Transcriptional regulator
JH395_RS14580	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
JH395_RS14600	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
JH395_RS14605	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
JH395_RS14625	COG2261	transglycosylase associated protein
JH395_RS14635	COG1393	Belongs to the ArsC family
JH395_RS14655	COG4512	PFAM Accessory gene regulator B
JH395_RS14670	COG1304	FMN binding
JH395_RS14675	COG0028	Belongs to the TPP enzyme family
JH395_RS14680	COG1959	2 iron, 2 sulfur cluster binding
JH395_RS14685	COG0028	Belongs to the TPP enzyme family
JH395_RS14700	COG0235	Class ii aldolase
JH395_RS14705	COG4806	L-rhamnose isomerase
JH395_RS14710	COG3254	rhamnose metabolic process
JH395_RS14715	COG1070	Carbohydrate kinase
JH395_RS14720	COG2814	Major facilitator Superfamily
JH395_RS14725	COG2207	Transcriptional regulator
JH395_RS14730	COG1349	DNA-binding transcription factor activity
JH395_RS14745	COG3775	system Galactitol-specific IIC component
JH395_RS14750	COG2801	Transposase and inactivated derivatives
JH395_RS14760	COG4975	Glucose uptake
JH395_RS14765	COG1869	D-ribose catabolic process
JH395_RS14775	COG1609	Transcriptional regulator
JH395_RS14805	COG1012	belongs to the aldehyde dehydrogenase family
JH395_RS14805	COG1454	alcohol dehydrogenase
JH395_RS14815	COG1695	Transcriptional regulator
JH395_RS14820	COG3479	Phenolic acid decarboxylase
JH395_RS14835	COG1307	EDD domain protein, DegV family
JH395_RS14875	COG0445	tRNA wobble uridine modification
JH395_RS14880	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
JH395_RS14885	COG1847	R3H domain protein
JH395_RS14890	COG0706	membrane insertase activity
JH395_RS14895	COG0594	ribonuclease P activity
JH395_RS14900	COG0230	Belongs to the bacterial ribosomal protein bL34 family
JH395_RS14975	COG1192	Involved in chromosome partitioning
JH395_RS14990	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
JH395_RS15025	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
JH395_RS15045	COG0446	pyridine nucleotide-disulphide oxidoreductase
JH395_RS15055	COG1388	LysM domain
JH395_RS15095	COG2095	MarC family integral membrane protein
JH395_RS15170	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
JH395_RS15180	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
JH395_RS15195	COG2826	transposase and inactivated derivatives, IS30 family
JH395_RS15205	COG2755	lipolytic protein G-D-S-L family
JH395_RS15205	COG0657	acetylesterase activity
JH395_RS15215	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
JH395_RS15265	COG0542	response to heat
JH395_RS15365	COG1053	succinate dehydrogenase
JH395_RS15385	COG1393	Belongs to the ArsC family
JH395_RS15390	COG2261	transglycosylase associated protein
JH395_RS15400	COG1388	LysM domain
JH395_RS15405	COG2826	transposase and inactivated derivatives, IS30 family
JH395_RS15430	COG4716	Myosin-crossreactive antigen
JH395_RS15440	COG4876	unkown
JH395_RS15450	COG2814	Major facilitator Superfamily
JH395_RS15455	COG5039	Polysaccharide pyruvyl transferase
JH395_RS15460	COG2814	Major facilitator Superfamily
JH395_RS15465	COG2261	transglycosylase associated protein
JH395_RS15485	COG0028	Belongs to the TPP enzyme family
JH395_RS15495	COG2376	Dihydroxyacetone kinase
JH395_RS15505	COG2376	Dihydroxyacetone kinase
JH395_RS15510	COG1461	Dihydroxyacetone kinase
JH395_RS15530	COG1846	Transcriptional regulator
JH395_RS15535	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
JH395_RS15555	COG3158	transport of potassium into the cell
JH395_RS15685	COG1192	Involved in chromosome partitioning
JH395_RS15690	COG3842	ATPase activity
JH395_RS15695	COG1653	transport
JH395_RS15785	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
JH395_RS15795	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
JH395_RS15920	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
JH395_RS15935	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
JH395_RS15945	COG2801	Transposase and inactivated derivatives
JH395_RS15960	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
JH395_RS15970	COG3394	polysaccharide catabolic process
JH395_RS15990	COG3715	PTS system
JH395_RS15995	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JH395_RS15995	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
JH395_RS16000	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
JH395_RS16000	COG3933	PFAM sigma-54 factor interaction domain-containing protein
JH395_RS16010	COG1940	carbohydrate kinase activity
JH395_RS16065	COG1192	Involved in chromosome partitioning
JH395_RS16150	COG2826	transposase and inactivated derivatives, IS30 family
JH395_RS16170	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
JH395_RS16180	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
JH395_RS16230	COG3409	Peptidoglycan-binding domain 1 protein
JH395_RS16240	COG2124	cytochrome p450
JH395_RS16370	COG0281	malic enzyme
JH395_RS16415	COG0783	Belongs to the Dps family
JH395_RS16420	COG3409	Peptidoglycan-binding domain 1 protein
JH395_RS16485	COG0582	viral genome integration into host DNA