locus-tag	class	description
CEB40_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
CEB40_RS00010	COG0592	DNA-directed DNA polymerase activity
CEB40_RS00015	COG2501	S4 domain
CEB40_RS00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
CEB40_RS00025	COG0187	DNA topoisomerase II activity
CEB40_RS00035	COG0360	Binds together with S18 to 16S ribosomal RNA
CEB40_RS00040	COG0629	single-stranded DNA binding
CEB40_RS00045	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
CEB40_RS00055	COG0359	binds to the 23S rRNA
CEB40_RS00060	COG0305	Participates in initiation and elongation during chromosome replication
CEB40_RS00065	COG2814	Major facilitator Superfamily
CEB40_RS00070	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
CEB40_RS00075	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
CEB40_RS00080	COG4166	transmembrane transport
CEB40_RS00085	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
CEB40_RS00090	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
CEB40_RS00095	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
CEB40_RS00100	COG0297	glycogen (starch) synthase activity
CEB40_RS00105	COG0058	SHG alpha-glucan phosphorylase activity
CEB40_RS00110	COG0366	Alpha amylase catalytic
CEB40_RS00110	COG3103	Sh3 type 3 domain protein
CEB40_RS00120	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CEB40_RS00125	COG1554	hydrolase, family 65, central catalytic
CEB40_RS00135	COG1278	Cold shock
CEB40_RS00150	COG0745	RESPONSE REGULATOR receiver
CEB40_RS00155	COG5002	protein histidine kinase activity
CEB40_RS00165	COG4853	Protein conserved in bacteria
CEB40_RS00170	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
CEB40_RS00175	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CEB40_RS00180	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
CEB40_RS00200	COG1573	uracil-dna glycosylase
CEB40_RS00220	COG3976	FMN-binding domain protein
CEB40_RS00220	COG1053	succinate dehydrogenase
CEB40_RS00220	COG0431	NADPH-dependent FMN reductase
CEB40_RS00225	COG0471	metal ion transport
CEB40_RS00240	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CEB40_RS00245	COG1028	Short-chain dehydrogenase reductase Sdr
CEB40_RS00260	COG2508	Transcriptional regulator
CEB40_RS00265	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CEB40_RS00270	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
CEB40_RS00280	COG2365	Tyrosine phosphatase family
CEB40_RS00285	COG2368	4-hydroxyphenylacetate
CEB40_RS00305	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
CEB40_RS00335	COG0604	alcohol dehydrogenase
CEB40_RS00350	COG2267	carboxylic ester hydrolase activity
CEB40_RS00355	COG3022	response to hydroperoxide
CEB40_RS00365	COG4166	transmembrane transport
CEB40_RS00390	COG1122	ATPase activity
CEB40_RS00395	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
CEB40_RS00400	COG0310	cobalt ion transport
CEB40_RS00405	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CEB40_RS00410	COG3875	lactate racemase activity
CEB40_RS00415	COG1691	(AIR) carboxylase
CEB40_RS00420	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
CEB40_RS00425	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
CEB40_RS00430	COG1606	tRNA processing
CEB40_RS00440	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
CEB40_RS00445	COG0351	phosphomethylpyrimidine kinase
CEB40_RS00450	COG0352	thiamine-phosphate diphosphorylase activity
CEB40_RS00460	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
CEB40_RS00475	COG1113	amino acid transport
CEB40_RS00485	COG2267	carboxylic ester hydrolase activity
CEB40_RS00490	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
CEB40_RS00495	COG1983	PspC domain protein
CEB40_RS00535	COG2807	transmembrane transport
CEB40_RS00540	COG0656	L-ascorbic acid biosynthetic process
CEB40_RS00545	COG0667	Aldo Keto reductase
CEB40_RS00575	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
CEB40_RS00580	COG1122	ATPase activity
CEB40_RS00585	COG4720	Psort location CytoplasmicMembrane, score
CEB40_RS00595	COG2188	Transcriptional regulator
CEB40_RS00620	COG1028	Short-chain dehydrogenase reductase Sdr
CEB40_RS00625	COG1131	(ABC) transporter
CEB40_RS00640	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
CEB40_RS00645	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
CEB40_RS00650	COG1309	transcriptional regulator
CEB40_RS00655	COG2376	Dihydroxyacetone kinase
CEB40_RS00660	COG2376	Dihydroxyacetone kinase
CEB40_RS00665	COG1461	Dihydroxyacetone kinase
CEB40_RS00670	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
CEB40_RS00675	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
CEB40_RS00680	COG1609	Transcriptional regulator
CEB40_RS00685	COG1609	Transcriptional regulator
CEB40_RS00690	COG0366	Alpha amylase catalytic
CEB40_RS00695	COG2182	Extracellular solute-binding protein
CEB40_RS00700	COG1175	transmembrane transport
CEB40_RS00705	COG3833	ABC-type maltose transport systems, permease component
CEB40_RS00715	COG0366	Alpha amylase catalytic
CEB40_RS00720	COG3842	ATPase activity
CEB40_RS00775	COG1757	Na H antiporter
CEB40_RS00800	COG4166	transmembrane transport
CEB40_RS00805	COG4166	transmembrane transport
CEB40_RS00815	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CEB40_RS00820	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
CEB40_RS00825	COG0406	alpha-ribazole phosphatase activity
CEB40_RS00830	COG0667	Aldo Keto reductase
CEB40_RS00860	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CEB40_RS00865	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CEB40_RS00870	COG0488	(ABC) transporter
CEB40_RS00880	COG4172	Belongs to the ABC transporter superfamily
CEB40_RS00890	COG0386	Belongs to the glutathione peroxidase family
CEB40_RS00900	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CEB40_RS00915	COG0363	glucosamine-6-phosphate deaminase activity
CEB40_RS00925	COG1053	succinate dehydrogenase
CEB40_RS00925	COG3976	FMN-binding domain protein
CEB40_RS00940	COG2213	PTS system mannitol-specific
CEB40_RS00950	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
CEB40_RS00955	COG0246	Mannitol dehydrogenase
CEB40_RS00965	COG3118	belongs to the thioredoxin family
CEB40_RS00995	COG0431	NADPH-dependent FMN reductase
CEB40_RS01000	COG2188	Transcriptional regulator
CEB40_RS01005	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CEB40_RS01020	COG3964	amidohydrolase
CEB40_RS01040	COG1045	serine acetyltransferase
CEB40_RS01045	COG0626	cystathionine gamma-synthase activity
CEB40_RS01050	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CEB40_RS01075	COG2188	Transcriptional regulator
CEB40_RS01080	COG0366	Alpha amylase catalytic
CEB40_RS01085	COG2190	(PTS) system
CEB40_RS01085	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CEB40_RS01085	COG1263	PTS System
CEB40_RS01090	COG2190	(PTS) system
CEB40_RS01090	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CEB40_RS01090	COG1263	PTS System
CEB40_RS01100	COG0163	prenyltransferase activity
CEB40_RS01110	COG1959	2 iron, 2 sulfur cluster binding
CEB40_RS01115	COG1309	transcriptional regulator
CEB40_RS01120	COG1914	H( )-stimulated, divalent metal cation uptake system
CEB40_RS01140	COG2814	Major facilitator Superfamily
CEB40_RS01145	COG0789	Transcriptional regulator
CEB40_RS01155	COG0745	RESPONSE REGULATOR receiver
CEB40_RS01165	COG1737	Transcriptional regulator
CEB40_RS01170	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CEB40_RS01185	COG1316	TRANSCRIPTIONal
CEB40_RS01190	COG0277	FAD linked oxidase domain protein
CEB40_RS01200	COG2357	RelA SpoT domain protein
CEB40_RS01210	COG2409	Drug exporters of the RND superfamily
CEB40_RS01210	COG1033	growth of symbiont in host cell
CEB40_RS01215	COG2818	Glycosylase
CEB40_RS01225	COG0577	efflux transmembrane transporter activity
CEB40_RS01230	COG1136	(ABC) transporter
CEB40_RS01245	COG0741	lytic transglycosylase activity
CEB40_RS01250	COG1388	LysM domain
CEB40_RS01250	COG3942	CHAP domain
CEB40_RS01280	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CEB40_RS01295	COG1846	Transcriptional regulator
CEB40_RS01300	COG1252	NADH dehydrogenase
CEB40_RS01325	COG3842	ATPase activity
CEB40_RS01355	COG1725	Transcriptional regulator
CEB40_RS01360	COG1131	(ABC) transporter
CEB40_RS01370	COG1454	alcohol dehydrogenase
CEB40_RS01370	COG1012	belongs to the aldehyde dehydrogenase family
CEB40_RS01405	COG1268	BioY protein
CEB40_RS01420	COG0436	Aminotransferase
CEB40_RS01430	COG1682	transport, permease protein
CEB40_RS01435	COG1134	teichoic acid transport
CEB40_RS01450	COG2814	Major facilitator Superfamily
CEB40_RS01455	COG0004	ammonium transporteR
CEB40_RS01475	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
CEB40_RS01485	COG3759	membrane
CEB40_RS01490	COG1881	PFAM PEBP family protein
CEB40_RS01520	COG0300	oxidoreductase activity
CEB40_RS01535	COG1125	glycine betaine transport
CEB40_RS01545	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CEB40_RS01555	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
CEB40_RS01585	COG0110	maltose O-acetyltransferase activity
CEB40_RS01595	COG0561	phosphatase activity
CEB40_RS01605	COG0561	phosphatase activity
CEB40_RS01610	COG1114	Component of the transport system for branched-chain amino acids
CEB40_RS01640	COG3290	protein histidine kinase activity
CEB40_RS01655	COG2801	Transposase and inactivated derivatives
CEB40_RS01680	COG2274	protein secretion by the type I secretion system
CEB40_RS01715	COG3973	AAA domain
CEB40_RS01720	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CEB40_RS01725	COG0180	Tryptophanyl-tRNA synthetase
CEB40_RS01730	COG2188	Transcriptional regulator
CEB40_RS01735	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CEB40_RS01750	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CEB40_RS01755	COG2723	6-phospho-beta-galactosidase activity
CEB40_RS01760	COG1940	carbohydrate kinase activity
CEB40_RS01770	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CEB40_RS01785	COG0248	Ppx GppA phosphatase
CEB40_RS01800	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
CEB40_RS01805	COG1801	Protein of unknown function DUF72
CEB40_RS01815	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CEB40_RS01815	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CEB40_RS01820	COG2814	Major facilitator Superfamily
CEB40_RS01825	COG0084	hydrolase, TatD family'
CEB40_RS01830	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
CEB40_RS01835	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
CEB40_RS01840	COG4466	Protein conserved in bacteria
CEB40_RS01845	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
CEB40_RS01855	COG1073	alpha beta
CEB40_RS01860	COG1121	(ABC) transporter
CEB40_RS01865	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CEB40_RS01865	COG1321	iron dependent repressor
CEB40_RS01870	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CEB40_RS01875	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
CEB40_RS01885	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CEB40_RS01905	COG1078	dGTPase activity
CEB40_RS01910	COG0095	Lipoate-protein ligase
CEB40_RS01920	COG3343	RNA polymerase activity
CEB40_RS01925	COG0504	CTP synthase activity
CEB40_RS01930	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
CEB40_RS01935	COG0814	amino acid
CEB40_RS01940	COG1760	l-serine dehydratase
CEB40_RS01945	COG1760	l-serine dehydratase
CEB40_RS01960	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CEB40_RS01965	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
CEB40_RS01970	COG0254	rRNA binding
CEB40_RS01980	COG3764	Sortase (surface protein transpeptidase)
CEB40_RS01985	COG1704	LemA family
CEB40_RS01990	COG0501	Belongs to the peptidase M48B family
CEB40_RS02000	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
CEB40_RS02015	COG0736	holo-[acyl-carrier-protein] synthase activity
CEB40_RS02020	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CEB40_RS02025	COG2337	Toxic component of a toxin-antitoxin (TA) module
CEB40_RS02030	COG3158	transport of potassium into the cell
CEB40_RS02050	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
CEB40_RS02055	COG0505	Belongs to the CarA family
CEB40_RS02060	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
CEB40_RS02065	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
CEB40_RS02070	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
CEB40_RS02075	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CEB40_RS02080	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
CEB40_RS02105	COG0039	L-malate dehydrogenase activity
CEB40_RS02110	COG0193	aminoacyl-tRNA hydrolase activity
CEB40_RS02115	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CEB40_RS02120	COG2244	polysaccharide biosynthetic process
CEB40_RS02125	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
CEB40_RS02135	COG1098	S1 RNA binding domain
CEB40_RS02140	COG0037	tRNA processing
CEB40_RS02155	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
CEB40_RS02160	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CEB40_RS02165	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
CEB40_RS02210	COG3104	oligopeptide transport
CEB40_RS02260	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CEB40_RS02270	COG2188	Transcriptional regulator
CEB40_RS02280	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
CEB40_RS02285	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
CEB40_RS02305	COG2183	response to ionizing radiation
CEB40_RS02310	COG3091	SprT-like family
CEB40_RS02315	COG0460	homoserine dehydrogenase
CEB40_RS02320	COG0083	homoserine kinase activity
CEB40_RS02330	COG0582	viral genome integration into host DNA
CEB40_RS02375	COG1396	sequence-specific DNA binding
CEB40_RS02515	COG0740	serine-type endopeptidase activity
CEB40_RS02615	COG3715	PTS system
CEB40_RS02620	COG3716	PTS system mannose fructose sorbose family IID component
CEB40_RS02630	COG3933	PFAM sigma-54 factor interaction domain-containing protein
CEB40_RS02630	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
CEB40_RS02635	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CEB40_RS02635	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
CEB40_RS02640	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CEB40_RS02640	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
CEB40_RS02645	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CEB40_RS02655	COG0439	Biotin carboxylase
CEB40_RS02665	COG0825	malonyl-CoA metabolic process
CEB40_RS02670	COG1316	TRANSCRIPTIONal
CEB40_RS02680	COG0697	spore germination
CEB40_RS02685	COG0588	phosphoglycerate mutase activity
CEB40_RS02700	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
CEB40_RS02710	COG0756	dUTP diphosphatase activity
CEB40_RS02720	COG4956	integral membrane protein (PIN domain superfamily)
CEB40_RS02725	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CEB40_RS02730	COG0215	cysteine-tRNA ligase activity
CEB40_RS02735	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
CEB40_RS02740	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CEB40_RS02755	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CEB40_RS02765	COG0250	Participates in transcription elongation, termination and antitermination
CEB40_RS02775	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
CEB40_RS02780	COG0081	regulation of translation
CEB40_RS02785	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
CEB40_RS02790	COG0222	ribosome binding
CEB40_RS02815	COG1611	Belongs to the LOG family
CEB40_RS02825	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CEB40_RS02830	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CEB40_RS02835	COG2813	Specifically methylates the guanine in position
CEB40_RS02850	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CEB40_RS02855	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
CEB40_RS02860	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
CEB40_RS02870	COG3711	transcriptional antiterminator
CEB40_RS02895	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
CEB40_RS02900	COG3870	Protein conserved in bacteria
CEB40_RS02905	COG0470	DNA polymerase III
CEB40_RS02910	COG4467	Involved in initiation control of chromosome replication
CEB40_RS02925	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CEB40_RS02930	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
CEB40_RS02935	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CEB40_RS02940	COG3639	organic phosphonate transmembrane transporter activity
CEB40_RS02950	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
CEB40_RS02960	COG1214	PFAM Peptidase M22, glycoprotease
CEB40_RS02965	COG0456	acetyltransferase
CEB40_RS02970	COG0456	acetyltransferase
CEB40_RS02975	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
CEB40_RS02980	COG0488	(ABC) transporter
CEB40_RS02985	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
CEB40_RS02995	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
CEB40_RS03000	COG0459	protein refolding
CEB40_RS03005	COG0531	amino acid
CEB40_RS03010	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CEB40_RS03015	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
CEB40_RS03020	COG1739	Uncharacterized protein family UPF0029
CEB40_RS03040	COG0653	protein targeting
CEB40_RS03055	COG0745	RESPONSE REGULATOR receiver
CEB40_RS03060	COG5002	protein histidine kinase activity
CEB40_RS03070	COG0573	inorganic phosphate transmembrane transporter activity
CEB40_RS03075	COG0581	inorganic phosphate transmembrane transporter activity
CEB40_RS03080	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CEB40_RS03085	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CEB40_RS03090	COG0704	Plays a role in the regulation of phosphate uptake
CEB40_RS03095	COG1983	PspC domain protein
CEB40_RS03100	COG1950	PFAM Membrane protein of
CEB40_RS03105	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
CEB40_RS03110	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
CEB40_RS03115	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
CEB40_RS03120	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CEB40_RS03130	COG0446	pyridine nucleotide-disulphide oxidoreductase
CEB40_RS03150	COG1215	transferase activity, transferring glycosyl groups
CEB40_RS03175	COG0492	ferredoxin-NADP+ reductase activity
CEB40_RS03180	COG2323	membrane
CEB40_RS03190	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CEB40_RS03200	COG0446	pyridine nucleotide-disulphide oxidoreductase
CEB40_RS03210	COG2814	Major facilitator Superfamily
CEB40_RS03220	COG0556	nucleotide-excision repair
CEB40_RS03225	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CEB40_RS03230	COG1854	S-ribosylhomocysteine lyase activity
CEB40_RS03235	COG0137	argininosuccinate synthase activity
CEB40_RS03240	COG0165	Argininosuccinate lyase
CEB40_RS03250	COG1660	Displays ATPase and GTPase activities
CEB40_RS03260	COG1481	regulation of sporulation
CEB40_RS03270	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CEB40_RS03275	COG0740	serine-type endopeptidase activity
CEB40_RS03285	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
CEB40_RS03290	COG2390	Transcriptional regulator
CEB40_RS03300	COG0126	phosphoglycerate kinase activity
CEB40_RS03305	COG0149	triose-phosphate isomerase activity
CEB40_RS03310	COG0148	phosphopyruvate hydratase activity
CEB40_RS03325	COG0038	chloride channel
CEB40_RS03330	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CEB40_RS03340	COG0557	exoribonuclease II activity
CEB40_RS03345	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
CEB40_RS03355	COG0765	amino acid transport
CEB40_RS03360	COG1126	abc transporter atp-binding protein
CEB40_RS03370	COG0561	phosphatase activity
CEB40_RS03375	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
CEB40_RS03380	COG0280	phosphate acetyltransferase
CEB40_RS03385	COG0802	atpase or kinase
CEB40_RS03400	COG0708	Exodeoxyribonuclease III
CEB40_RS03410	COG0812	UDP-N-acetylmuramate dehydrogenase activity
CEB40_RS03415	COG0025	NhaP-type Na H and K H
CEB40_RS03440	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CEB40_RS03445	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CEB40_RS03455	COG0561	phosphatase activity
CEB40_RS03465	COG2017	converts alpha-aldose to the beta-anomer
CEB40_RS03485	COG0778	Nitroreductase
CEB40_RS03510	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CEB40_RS03525	COG1393	Belongs to the ArsC family
CEB40_RS03540	COG0477	Major facilitator Superfamily
CEB40_RS03545	COG0248	Ppx GppA phosphatase
CEB40_RS03545	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
CEB40_RS03550	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
CEB40_RS03560	COG3475	LICD family
CEB40_RS03575	COG2252	PERMEase
CEB40_RS03580	COG0028	Belongs to the TPP enzyme family
CEB40_RS03585	COG0196	riboflavin kinase activity
CEB40_RS03590	COG0028	Belongs to the TPP enzyme family
CEB40_RS03595	COG2267	carboxylic ester hydrolase activity
CEB40_RS03605	COG2755	lipolytic protein G-D-S-L family
CEB40_RS03605	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
CEB40_RS03610	COG2936	dipeptidyl-peptidase activity
CEB40_RS03625	COG0531	amino acid
CEB40_RS03650	COG0194	GDP metabolic process
CEB40_RS03655	COG0735	belongs to the Fur family
CEB40_RS03670	COG0546	phosphoglycolate phosphatase activity
CEB40_RS03675	COG0436	Aminotransferase
CEB40_RS03680	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CEB40_RS03695	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CEB40_RS03700	COG0765	amino acid transport
CEB40_RS03705	COG0765	amino acid transport
CEB40_RS03715	COG2190	(PTS) system
CEB40_RS03715	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CEB40_RS03715	COG1263	PTS System
CEB40_RS03725	COG1263	PTS System
CEB40_RS03725	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CEB40_RS03730	COG3394	polysaccharide catabolic process
CEB40_RS03735	COG0531	amino acid
CEB40_RS03740	COG1846	Transcriptional regulator
CEB40_RS03770	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CEB40_RS03780	COG2076	Multidrug Resistance protein
CEB40_RS03795	COG0588	phosphoglycerate mutase activity
CEB40_RS03800	COG0569	domain protein
CEB40_RS03800	COG0475	glutathione-regulated potassium exporter activity
CEB40_RS03805	COG0456	acetyltransferase
CEB40_RS03805	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
CEB40_RS03825	COG1263	PTS System
CEB40_RS03825	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CEB40_RS03825	COG2190	(PTS) system
CEB40_RS03830	COG2723	6-phospho-beta-galactosidase activity
CEB40_RS03840	COG3973	AAA domain
CEB40_RS03845	COG2070	2-Nitropropane dioxygenase
CEB40_RS03850	COG1072	(Pantothenic acid kinase))
CEB40_RS03855	COG0519	Catalyzes the synthesis of GMP from XMP
CEB40_RS03855	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CEB40_RS03865	COG1396	sequence-specific DNA binding
CEB40_RS03875	COG1266	CAAX protease self-immunity
CEB40_RS03880	COG1733	regulation of RNA biosynthetic process
CEB40_RS03885	COG2814	Major facilitator Superfamily
CEB40_RS03900	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
CEB40_RS03900	COG2755	lipolytic protein G-D-S-L family
CEB40_RS03905	COG2261	transglycosylase associated protein
CEB40_RS03920	COG1302	Protein conserved in bacteria
CEB40_RS03950	COG0308	aminopeptidase N
CEB40_RS03980	COG0572	uridine kinase
CEB40_RS03995	COG0583	DNA-binding transcription factor activity
CEB40_RS04000	COG1053	succinate dehydrogenase
CEB40_RS04010	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
CEB40_RS04035	COG2502	aspartate--ammonia ligase
CEB40_RS04040	COG4690	dipeptidase activity
CEB40_RS04060	COG0514	ATP-dependent DNA helicase (RecQ)
CEB40_RS04065	COG0564	pseudouridine synthase activity
CEB40_RS04070	COG0640	Transcriptional regulator
CEB40_RS04120	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CEB40_RS04125	COG0527	aspartate kinase activity
CEB40_RS04130	COG0367	asparagine synthase
CEB40_RS04170	COG2814	Major facilitator Superfamily
CEB40_RS04190	COG1278	Cold shock
CEB40_RS04195	COG2966	Psort location CytoplasmicMembrane, score
CEB40_RS04205	COG1316	TRANSCRIPTIONal
CEB40_RS04230	COG1959	2 iron, 2 sulfur cluster binding
CEB40_RS04235	COG0028	Belongs to the TPP enzyme family
CEB40_RS04240	COG0833	amino acid
CEB40_RS04250	COG1428	Deoxynucleoside kinase
CEB40_RS04255	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
CEB40_RS04295	COG4463	regulation of RNA biosynthetic process
CEB40_RS04300	COG0542	response to heat
CEB40_RS04310	COG0085	RNA polymerase activity
CEB40_RS04315	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CEB40_RS04320	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
CEB40_RS04325	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
CEB40_RS04330	COG0049	tRNA binding
CEB40_RS04335	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CEB40_RS04340	COG0051	transcription antitermination factor activity, RNA binding
CEB40_RS04345	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
CEB40_RS04350	COG0088	Forms part of the polypeptide exit tunnel
CEB40_RS04355	COG0089	rRNA binding
CEB40_RS04360	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
CEB40_RS04365	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
CEB40_RS04370	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
CEB40_RS04375	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
CEB40_RS04380	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
CEB40_RS04385	COG0255	Belongs to the universal ribosomal protein uL29 family
CEB40_RS04390	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
CEB40_RS04395	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
CEB40_RS04400	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
CEB40_RS04405	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
CEB40_RS04410	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
CEB40_RS04415	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
CEB40_RS04420	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
CEB40_RS04425	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
CEB40_RS04430	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
CEB40_RS04435	COG1841	ribosomal large subunit assembly
CEB40_RS04440	COG0200	Binds to the 23S rRNA
CEB40_RS04450	COG0563	adenylate kinase activity
CEB40_RS04455	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
CEB40_RS04460	COG0257	Belongs to the bacterial ribosomal protein bL36 family
CEB40_RS04465	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
CEB40_RS04470	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
CEB40_RS04475	COG0202	RNA polymerase activity
CEB40_RS04480	COG0203	ribosomal protein L17
CEB40_RS04505	COG4939	FMN-binding domain protein
CEB40_RS04515	COG1122	ATPase activity
CEB40_RS04520	COG1122	ATPase activity
CEB40_RS04530	COG0101	tRNA pseudouridine synthase activity
CEB40_RS04535	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
CEB40_RS04540	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
CEB40_RS04565	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CEB40_RS04570	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
CEB40_RS04575	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
CEB40_RS04585	COG2151	metal-sulfur cluster biosynthetic enzyme
CEB40_RS04590	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
CEB40_RS04600	COG1917	Cupin 2, conserved barrel domain protein
CEB40_RS04600	COG4977	sequence-specific DNA binding
CEB40_RS04605	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
CEB40_RS04610	COG1121	(ABC) transporter
CEB40_RS04620	COG2826	transposase and inactivated derivatives, IS30 family
CEB40_RS04630	COG0803	Belongs to the bacterial solute-binding protein 9 family
CEB40_RS04640	COG0039	L-malate dehydrogenase activity
CEB40_RS04645	COG0471	metal ion transport
CEB40_RS04665	COG3052	prosthetic group binding
CEB40_RS04700	COG0114	fumarate hydratase activity
CEB40_RS04705	COG1053	succinate dehydrogenase
CEB40_RS04715	COG0583	DNA-binding transcription factor activity
CEB40_RS04720	COG0583	DNA-binding transcription factor activity
CEB40_RS04725	COG0281	malic enzyme
CEB40_RS04735	COG0531	amino acid
CEB40_RS04740	COG4684	Psort location CytoplasmicMembrane, score
CEB40_RS04755	COG1271	oxidase subunit
CEB40_RS04760	COG1294	oxidase, subunit
CEB40_RS04765	COG4988	ABC transporter
CEB40_RS04770	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
CEB40_RS04785	COG0142	geranyltranstransferase activity
CEB40_RS04800	COG1705	Flagellar rod assembly protein muramidase FlgJ
CEB40_RS04805	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CEB40_RS04810	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
CEB40_RS04815	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
CEB40_RS04825	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CEB40_RS04830	COG4851	CamS sex pheromone cAM373 precursor
CEB40_RS04835	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CEB40_RS04840	COG0154	amidase activity
CEB40_RS04845	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CEB40_RS04850	COG1597	lipid kinase activity
CEB40_RS04855	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CEB40_RS04870	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CEB40_RS04880	COG1737	Transcriptional regulator
CEB40_RS04895	COG1278	Cold shock
CEB40_RS04900	COG0673	inositol 2-dehydrogenase activity
CEB40_RS04905	COG0513	Belongs to the DEAD box helicase family
CEB40_RS04920	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CEB40_RS04945	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CEB40_RS04955	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
CEB40_RS04965	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
CEB40_RS04970	COG0562	UDP-galactopyranose mutase
CEB40_RS05015	COG2244	polysaccharide biosynthetic process
CEB40_RS05020	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
CEB40_RS05030	COG1088	dTDP-glucose 4,6-dehydratase activity
CEB40_RS05035	COG0582	viral genome integration into host DNA
CEB40_RS05055	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CEB40_RS05090	COG2137	regulation of response to DNA damage stimulus
CEB40_RS05095	COG3557	Belongs to the UPF0374 family
CEB40_RS05115	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CEB40_RS05125	COG0628	permease
CEB40_RS05130	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
CEB40_RS05135	COG2610	gluconate transmembrane transporter activity
CEB40_RS05140	COG1070	Carbohydrate kinase
CEB40_RS05145	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
CEB40_RS05150	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CEB40_RS05155	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
CEB40_RS05190	COG4166	transmembrane transport
CEB40_RS05195	COG0601	transmembrane transport
CEB40_RS05200	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CEB40_RS05205	COG0444	Belongs to the ABC transporter superfamily
CEB40_RS05210	COG4608	Belongs to the ABC transporter superfamily
CEB40_RS05220	COG0582	viral genome integration into host DNA
CEB40_RS05225	COG0542	response to heat
CEB40_RS05245	COG0438	transferase activity, transferring glycosyl groups
CEB40_RS05250	COG0438	transferase activity, transferring glycosyl groups
CEB40_RS05260	COG1686	Belongs to the peptidase S11 family
CEB40_RS05265	COG0436	Aminotransferase
CEB40_RS05270	COG4703	Protein of unknown function (DUF1797)
CEB40_RS05275	COG1368	sulfuric ester hydrolase activity
CEB40_RS05360	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CEB40_RS05380	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
CEB40_RS05385	COG2207	Transcriptional regulator
CEB40_RS05385	COG4753	response regulator
CEB40_RS05400	COG1940	carbohydrate kinase activity
CEB40_RS05410	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
CEB40_RS05415	COG0833	amino acid
CEB40_RS05420	COG2040	homocysteine
CEB40_RS05425	COG0438	transferase activity, transferring glycosyl groups
CEB40_RS05435	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
CEB40_RS05440	COG0477	Major facilitator Superfamily
CEB40_RS05455	COG0438	transferase activity, transferring glycosyl groups
CEB40_RS05470	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
CEB40_RS05480	COG0495	leucyl-tRNA aminoacylation
CEB40_RS05485	COG2244	polysaccharide biosynthetic process
CEB40_RS05490	COG1187	pseudouridine synthase activity
CEB40_RS05495	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
CEB40_RS05500	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CEB40_RS05510	COG3842	ATPase activity
CEB40_RS05515	COG1175	transmembrane transport
CEB40_RS05520	COG0395	ABC-type sugar transport system, permease component
CEB40_RS05530	COG0584	glycerophosphoryl diester phosphodiesterase
CEB40_RS05535	COG1428	Deoxynucleoside kinase
CEB40_RS05540	COG1970	mechanosensitive ion channel activity
CEB40_RS05545	COG1511	domain protein
CEB40_RS05575	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CEB40_RS05580	COG0789	Transcriptional regulator
CEB40_RS05590	COG0697	spore germination
CEB40_RS05595	COG0561	phosphatase activity
CEB40_RS05615	COG3279	Response regulator of the LytR AlgR family
CEB40_RS05635	COG1846	Transcriptional regulator
CEB40_RS05650	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CEB40_RS05690	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
CEB40_RS05690	COG0646	methionine synthase
CEB40_RS05695	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
CEB40_RS05705	COG2046	Belongs to the sulfate adenylyltransferase family
CEB40_RS05710	COG0529	Catalyzes the synthesis of activated sulfate
CEB40_RS05715	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
CEB40_RS05725	COG0471	metal ion transport
CEB40_RS05725	COG3273	potassium ion transport
CEB40_RS05730	COG0534	Mate efflux family protein
CEB40_RS05750	COG2153	protein acetylation
CEB40_RS05755	COG0018	arginyl-trna synthetase
CEB40_RS05765	COG0577	efflux transmembrane transporter activity
CEB40_RS05765	COG1136	(ABC) transporter
CEB40_RS05785	COG1447	Phosphotransferase system cellobiose-specific component IIA
CEB40_RS05790	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CEB40_RS05795	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CEB40_RS05800	COG2723	6-phospho-beta-galactosidase activity
CEB40_RS05810	COG1376	ErfK ybiS ycfS ynhG family protein
CEB40_RS05815	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CEB40_RS05820	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CEB40_RS05830	COG0436	Aminotransferase
CEB40_RS05835	COG1438	arginine binding
CEB40_RS05845	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CEB40_RS05850	COG3679	Belongs to the UPF0342 family
CEB40_RS05855	COG0420	3'-5' exonuclease activity
CEB40_RS05860	COG4717	serine-type aminopeptidase activity
CEB40_RS05865	COG3481	metal-dependent phosphohydrolase, HD sub domain
CEB40_RS05880	COG0583	DNA-binding transcription factor activity
CEB40_RS05890	COG3976	FMN-binding domain protein
CEB40_RS05890	COG1053	succinate dehydrogenase
CEB40_RS05890	COG0431	NADPH-dependent FMN reductase
CEB40_RS05910	COG0463	Glycosyl transferase, family 2
CEB40_RS05925	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CEB40_RS05925	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CEB40_RS05930	COG0307	riboflavin synthase, alpha
CEB40_RS05935	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CEB40_RS05935	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CEB40_RS05940	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
CEB40_RS05960	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CEB40_RS05970	COG0446	pyridine nucleotide-disulphide oxidoreductase
CEB40_RS06000	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CEB40_RS06010	COG0537	adenosine 5'-monophosphoramidase activity
CEB40_RS06015	COG1131	(ABC) transporter
CEB40_RS06020	COG4473	ABC transporter
CEB40_RS06025	COG0510	thiamine kinase activity
CEB40_RS06030	COG0220	tRNA (guanine-N7-)-methyltransferase activity
CEB40_RS06040	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CEB40_RS06045	COG1674	ftsk spoiiie
CEB40_RS06050	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CEB40_RS06075	COG0719	Fe-S assembly protein
CEB40_RS06080	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CEB40_RS06090	COG0719	Fe-S assembly protein
CEB40_RS06100	COG1120	ATPase activity
CEB40_RS06110	COG0716	FMN binding
CEB40_RS06125	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
CEB40_RS06130	COG2223	nitrite transmembrane transporter activity
CEB40_RS06135	COG2151	metal-sulfur cluster biosynthetic enzyme
CEB40_RS06160	COG2197	response regulator
CEB40_RS06185	COG0315	cyclic pyranopterin monophosphate synthase activity
CEB40_RS06190	COG1763	Mo-molybdopterin cofactor biosynthetic process
CEB40_RS06195	COG0303	'Molybdopterin
CEB40_RS06205	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CEB40_RS06210	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
CEB40_RS06215	COG1140	nitrate reductase beta subunit
CEB40_RS06225	COG2181	nitrate reductase activity
CEB40_RS06245	COG3655	Transcriptional regulator
CEB40_RS06255	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CEB40_RS06255	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CEB40_RS06260	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
CEB40_RS06265	COG0237	dephospho-CoA kinase activity
CEB40_RS06270	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
CEB40_RS06275	COG3611	Membrane attachment protein
CEB40_RS06280	COG1484	DNA-dependent DNA replication
CEB40_RS06285	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
CEB40_RS06290	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
CEB40_RS06295	COG0291	Belongs to the bacterial ribosomal protein bL35 family
CEB40_RS06300	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
CEB40_RS06310	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CEB40_RS06315	COG0604	alcohol dehydrogenase
CEB40_RS06320	COG1733	regulation of RNA biosynthetic process
CEB40_RS06330	COG1215	transferase activity, transferring glycosyl groups
CEB40_RS06350	COG1534	Rna-binding protein
CEB40_RS06355	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
CEB40_RS06360	COG1713	HD superfamily hydrolase involved in NAD metabolism
CEB40_RS06365	COG0799	negative regulation of ribosome biogenesis
CEB40_RS06370	COG2226	methyltransferase
CEB40_RS06375	COG1323	Belongs to the UPF0348 family
CEB40_RS06385	COG0333	Belongs to the bacterial ribosomal protein bL32 family
CEB40_RS06400	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
CEB40_RS06405	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CEB40_RS06410	COG0745	RESPONSE REGULATOR receiver
CEB40_RS06415	COG5002	protein histidine kinase activity
CEB40_RS06425	COG0419	ATPase involved in DNA repair
CEB40_RS06440	COG0706	membrane insertase activity
CEB40_RS06445	COG1254	Belongs to the acylphosphatase family
CEB40_RS06450	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CEB40_RS06460	COG1733	regulation of RNA biosynthetic process
CEB40_RS06465	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
CEB40_RS06470	COG0072	phenylalanine-tRNA ligase activity
CEB40_RS06470	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CEB40_RS06475	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CEB40_RS06480	COG0572	uridine kinase
CEB40_RS06485	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CEB40_RS06500	COG4841	protein insertion into membrane
CEB40_RS06510	COG0768	penicillin binding
CEB40_RS06515	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CEB40_RS06520	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
CEB40_RS06525	COG0705	Rhomboid family
CEB40_RS06525	COG0457	Tetratricopeptide repeat
CEB40_RS06535	COG1940	carbohydrate kinase activity
CEB40_RS06555	COG0584	glycerophosphoryl diester phosphodiesterase
CEB40_RS06560	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
CEB40_RS06565	COG0789	Transcriptional regulator
CEB40_RS06615	COG0261	This protein binds to 23S rRNA in the presence of protein L20
CEB40_RS06625	COG0211	Belongs to the bacterial ribosomal protein bL27 family
CEB40_RS06630	COG0006	proline dipeptidase activity
CEB40_RS06635	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
CEB40_RS06640	COG1302	Protein conserved in bacteria
CEB40_RS06645	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CEB40_RS06650	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
CEB40_RS06655	COG1570	exodeoxyribonuclease VII activity
CEB40_RS06660	COG1722	exodeoxyribonuclease VII activity
CEB40_RS06665	COG0142	geranyltranstransferase activity
CEB40_RS06670	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
CEB40_RS06675	COG1438	arginine binding
CEB40_RS06680	COG0497	DNA recombination
CEB40_RS06695	COG1732	Glycine betaine
CEB40_RS06710	COG0194	GDP metabolic process
CEB40_RS06715	COG1758	RNA polymerase activity
CEB40_RS06720	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CEB40_RS06725	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CEB40_RS06730	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CEB40_RS06735	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CEB40_RS06735	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CEB40_RS06740	COG0631	protein serine/threonine phosphatase activity
CEB40_RS06745	COG2815	serine threonine protein kinase
CEB40_RS06745	COG0515	serine threonine protein kinase
CEB40_RS06750	COG1162	GTPase activity
CEB40_RS06755	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CEB40_RS06760	COG1564	THIamine pyrophosphokinase
CEB40_RS06770	COG0227	Belongs to the bacterial ribosomal protein bL28 family
CEB40_RS06775	COG1302	Protein conserved in bacteria
CEB40_RS06780	COG1461	Dihydroxyacetone kinase
CEB40_RS06785	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CEB40_RS06790	COG0416	fatty acid biosynthetic process
CEB40_RS06795	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CEB40_RS06800	COG0571	ribonuclease III activity
CEB40_RS06805	COG1196	nuclear chromosome segregation
CEB40_RS06810	COG0552	protein localization to endoplasmic reticulum
CEB40_RS06815	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
CEB40_RS06820	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CEB40_RS06825	COG0228	four-way junction DNA binding
CEB40_RS06830	COG1837	Belongs to the UPF0109 family
CEB40_RS06835	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
CEB40_RS06840	COG0336	Belongs to the RNA methyltransferase TrmD family
CEB40_RS06845	COG0335	large ribosomal subunit rRNA binding
CEB40_RS06870	COG1309	transcriptional regulator
CEB40_RS06875	COG1063	alcohol dehydrogenase
CEB40_RS06905	COG2814	Major facilitator Superfamily
CEB40_RS06910	COG1131	(ABC) transporter
CEB40_RS06925	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CEB40_RS06925	COG0512	Glutamine amidotransferase of anthranilate synthase
CEB40_RS06930	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CEB40_RS06935	COG0134	indole-3-glycerol-phosphate synthase activity
CEB40_RS06940	COG0135	phosphoribosylanthranilate isomerase activity
CEB40_RS06945	COG0133	tryptophan synthase activity
CEB40_RS06950	COG0159	tryptophan synthase activity
CEB40_RS06965	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CEB40_RS06975	COG1473	amidohydrolase
CEB40_RS06980	COG1063	alcohol dehydrogenase
CEB40_RS06990	COG0300	oxidoreductase activity
CEB40_RS07000	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CEB40_RS07005	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CEB40_RS07010	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CEB40_RS07015	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
CEB40_RS07020	COG1028	Short-chain dehydrogenase reductase Sdr
CEB40_RS07025	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CEB40_RS07040	COG0439	Biotin carboxylase
CEB40_RS07055	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
CEB40_RS07065	COG1811	Na channel or pump
CEB40_RS07070	COG0583	DNA-binding transcription factor activity
CEB40_RS07075	COG1607	acyl-coa hydrolase
CEB40_RS07080	COG1162	GTPase activity
CEB40_RS07135	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CEB40_RS07140	COG3397	chitin binding
CEB40_RS07155	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
CEB40_RS07165	COG3152	Membrane
CEB40_RS07170	COG1597	lipid kinase activity
CEB40_RS07200	COG3237	CsbD-like
CEB40_RS07215	COG1942	4-Oxalocrotonate Tautomerase
CEB40_RS07250	COG0531	amino acid
CEB40_RS07255	COG0561	phosphatase activity
CEB40_RS07260	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
CEB40_RS07260	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CEB40_RS07280	COG2017	converts alpha-aldose to the beta-anomer
CEB40_RS07285	COG1304	FMN binding
CEB40_RS07310	COG1199	ATP-dependent helicase activity
CEB40_RS07310	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CEB40_RS07325	COG0017	Asparaginyl-tRNA synthetase
CEB40_RS07340	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CEB40_RS07345	COG2011	ABC-type metal ion transport system permease component
CEB40_RS07350	COG1464	Belongs to the NlpA lipoprotein family
CEB40_RS07360	COG1177	transmembrane transport
CEB40_RS07365	COG1840	ABC-type Fe3 transport system, periplasmic component
CEB40_RS07380	COG3331	DNA recombination
CEB40_RS07390	COG3599	regulation of cell shape
CEB40_RS07400	COG0116	Belongs to the methyltransferase superfamily
CEB40_RS07425	COG1073	alpha beta
CEB40_RS07455	COG1619	proteins homologs of microcin C7 resistance protein MccF
CEB40_RS07480	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CEB40_RS07495	COG2759	Belongs to the formate--tetrahydrofolate ligase family
CEB40_RS07500	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
CEB40_RS07505	COG0564	pseudouridine synthase activity
CEB40_RS07510	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
CEB40_RS07515	COG0505	Belongs to the CarA family
CEB40_RS07520	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
CEB40_RS07570	COG1293	RNA-binding protein homologous to eukaryotic snRNP
CEB40_RS07580	COG1307	EDD domain protein, DegV family
CEB40_RS07650	COG1620	l-lactate permease
CEB40_RS07660	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
CEB40_RS07690	COG1846	Transcriptional regulator
CEB40_RS07730	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CEB40_RS07735	COG1227	inorganic diphosphatase activity
CEB40_RS07740	COG0583	DNA-binding transcription factor activity
CEB40_RS07750	COG0187	DNA topoisomerase II activity
CEB40_RS07755	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
CEB40_RS07765	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
CEB40_RS07770	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
CEB40_RS07775	COG4974	Belongs to the 'phage' integrase family
CEB40_RS07780	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
CEB40_RS07785	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CEB40_RS07790	COG0758	DNA mediated transformation
CEB40_RS07795	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CEB40_RS07800	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
CEB40_RS07805	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
CEB40_RS07810	COG0583	DNA-binding transcription factor activity
CEB40_RS07830	COG2814	Major facilitator Superfamily
CEB40_RS07835	COG0793	Belongs to the peptidase S41A family
CEB40_RS07835	COG3409	Peptidoglycan-binding domain 1 protein
CEB40_RS07840	COG4479	Belongs to the UPF0346 family
CEB40_RS07845	COG4698	Protein conserved in bacteria
CEB40_RS07850	COG2755	lipolytic protein G-D-S-L family
CEB40_RS07855	COG1307	EDD domain protein, DegV family
CEB40_RS07860	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
CEB40_RS07865	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
CEB40_RS07870	COG0488	(ABC) transporter
CEB40_RS07880	COG0617	tRNA 3'-terminal CCA addition
CEB40_RS07885	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
CEB40_RS07890	COG0561	phosphatase activity
CEB40_RS07895	COG0457	Tetratricopeptide repeat
CEB40_RS07910	COG1160	GTP binding
CEB40_RS07915	COG0539	negative regulation of cytoplasmic translation
CEB40_RS07920	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
CEB40_RS07930	COG0514	ATP-dependent DNA helicase (RecQ)
CEB40_RS07940	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
CEB40_RS07945	COG1187	pseudouridine synthase activity
CEB40_RS07950	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
CEB40_RS07955	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
CEB40_RS07965	COG4974	Belongs to the 'phage' integrase family
CEB40_RS07970	COG2996	Protein conserved in bacteria
CEB40_RS07990	COG0205	6-phosphofructokinase activity
CEB40_RS07995	COG0587	DNA-directed DNA polymerase activity
CEB40_RS08005	COG0542	response to heat
CEB40_RS08015	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
CEB40_RS08020	COG2384	SAM-dependent methyltransferase
CEB40_RS08050	COG0574	Belongs to the PEP-utilizing enzyme family
CEB40_RS08050	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CEB40_RS08060	COG1846	Transcriptional regulator
CEB40_RS08080	COG2217	Heavy metal translocating P-type atpase
CEB40_RS08085	COG0148	phosphopyruvate hydratase activity
CEB40_RS08090	COG0477	Major facilitator Superfamily
CEB40_RS08100	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CEB40_RS08105	COG0446	pyridine nucleotide-disulphide oxidoreductase
CEB40_RS08110	COG1349	DNA-binding transcription factor activity
CEB40_RS08120	COG1393	Belongs to the ArsC family
CEB40_RS08165	COG0546	phosphoglycolate phosphatase activity
CEB40_RS08195	COG0583	DNA-binding transcription factor activity
CEB40_RS08200	COG0604	alcohol dehydrogenase
CEB40_RS08210	COG0446	pyridine nucleotide-disulphide oxidoreductase
CEB40_RS08215	COG2197	response regulator
CEB40_RS08220	COG4585	Histidine kinase
CEB40_RS08230	COG1131	(ABC) transporter
CEB40_RS08240	COG0519	Catalyzes the synthesis of GMP from XMP
CEB40_RS08265	COG1131	(ABC) transporter
CEB40_RS08285	COG1131	(ABC) transporter
CEB40_RS08290	COG1725	Transcriptional regulator
CEB40_RS08295	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CEB40_RS08300	COG0358	DNA primase activity
CEB40_RS08310	COG0752	glycyl-tRNA synthetase alpha subunit
CEB40_RS08320	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
CEB40_RS08325	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
CEB40_RS08330	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
CEB40_RS08335	COG1702	phosphate starvation-inducible protein PhoH
CEB40_RS08340	COG1610	YqeY-like protein
CEB40_RS08345	COG0828	Belongs to the bacterial ribosomal protein bS21 family
CEB40_RS08350	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
CEB40_RS08360	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
CEB40_RS08370	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CEB40_RS08380	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
CEB40_RS08385	COG0124	histidyl-tRNA synthetase
CEB40_RS08390	COG4991	sh3 domain protein
CEB40_RS08390	COG0860	N-Acetylmuramoyl-L-alanine amidase
CEB40_RS08390	COG3103	Sh3 type 3 domain protein
CEB40_RS08395	COG3001	Fructosamine kinase
CEB40_RS08400	COG0546	phosphoglycolate phosphatase activity
CEB40_RS08405	COG1490	D-aminoacyl-tRNA deacylase activity
CEB40_RS08410	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CEB40_RS08420	COG1385	rRNA (uridine-N3-)-methyltransferase activity
CEB40_RS08425	COG2264	protein methyltransferase activity
CEB40_RS08430	COG2094	Belongs to the DNA glycosylase MPG family
CEB40_RS08445	COG0481	GTPase activity
CEB40_RS08450	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
CEB40_RS08455	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CEB40_RS08460	COG1696	Membrane protein involved in D-alanine export
CEB40_RS08465	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CEB40_RS08475	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CEB40_RS08480	COG0484	heat shock protein binding
CEB40_RS08485	COG0443	Heat shock 70 kDa protein
CEB40_RS08490	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
CEB40_RS08495	COG1420	regulation of RNA biosynthetic process
CEB40_RS08500	COG3527	Alpha-acetolactate decarboxylase
CEB40_RS08505	COG0196	riboflavin kinase activity
CEB40_RS08510	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
CEB40_RS08515	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
CEB40_RS08520	COG0287	Prephenate dehydrogenase
CEB40_RS08525	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
CEB40_RS08535	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
CEB40_RS08540	COG0738	Major facilitator superfamily
CEB40_RS08545	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
CEB40_RS08550	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
CEB40_RS08560	COG2740	Nucleic-acid-binding protein implicated in transcription termination
CEB40_RS08565	COG0195	Participates in both transcription termination and antitermination
CEB40_RS08570	COG0779	Required for maturation of 30S ribosomal subunits
CEB40_RS08575	COG2176	DNA-directed DNA polymerase activity
CEB40_RS08580	COG0442	prolyl-tRNA aminoacylation
CEB40_RS08585	COG0750	zinc metalloprotease
CEB40_RS08590	COG4589	Belongs to the CDS family
CEB40_RS08595	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CEB40_RS08600	COG0233	cytoplasmic translational termination
CEB40_RS08605	COG0528	UMP kinase activity
CEB40_RS08610	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
CEB40_RS08615	COG0052	Belongs to the universal ribosomal protein uS2 family
CEB40_RS08625	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CEB40_RS08630	COG2827	Endonuclease containing a URI domain
CEB40_RS08635	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
CEB40_RS08640	COG0204	Acyl-transferase
CEB40_RS08645	COG3763	UPF0154 protein
CEB40_RS08650	COG4224	UPF0291 protein
CEB40_RS08655	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CEB40_RS08670	COG3425	synthase
CEB40_RS08685	COG0463	Glycosyl transferase, family 2
CEB40_RS08750	COG0393	Putative heavy-metal-binding
CEB40_RS08765	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CEB40_RS08770	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
CEB40_RS08770	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
CEB40_RS08775	COG5416	Lipopolysaccharide assembly protein A domain
CEB40_RS08780	COG0300	oxidoreductase activity
CEB40_RS08785	COG1234	tRNA 3'-trailer cleavage
CEB40_RS08795	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
CEB40_RS08800	COG1349	DNA-binding transcription factor activity
CEB40_RS08805	COG1105	Belongs to the carbohydrate kinase PfkB family
CEB40_RS08810	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CEB40_RS08810	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CEB40_RS08810	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CEB40_RS08815	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
CEB40_RS08840	COG0297	glycogen (starch) synthase activity
CEB40_RS08845	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CEB40_RS08850	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CEB40_RS08860	COG0489	protein tyrosine kinase activity
CEB40_RS08870	COG0322	excinuclease ABC activity
CEB40_RS08875	COG1126	abc transporter atp-binding protein
CEB40_RS08880	COG0765	amino acid transport
CEB40_RS08910	COG0218	Necessary for normal cell division and for the maintenance of normal septation
CEB40_RS08915	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
CEB40_RS08920	COG0544	peptidyl-prolyl cis-trans isomerase activity
CEB40_RS08925	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CEB40_RS08950	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
CEB40_RS08955	COG0268	Binds directly to 16S ribosomal RNA
CEB40_RS08960	COG1466	dna polymerase III delta subunit
CEB40_RS08965	COG2333	competence protein COMEC
CEB40_RS08965	COG0658	competence protein
CEB40_RS08970	COG2131	deaminase
CEB40_RS08975	COG1596	polysaccharide export
CEB40_RS08975	COG1555	photosystem II stabilization
CEB40_RS08980	COG3480	Lon protease (S16) C-terminal proteolytic domain
CEB40_RS08985	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
CEB40_RS08990	COG0742	ribosomal rna small subunit methyltransferase
CEB40_RS08995	COG4471	UPF0298 protein
CEB40_RS09000	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
CEB40_RS09005	COG0772	Belongs to the SEDS family
CEB40_RS09035	COG1217	gtp-binding protein TYPA
CEB40_RS09040	COG0483	inositol monophosphate 1-phosphatase activity
CEB40_RS09045	COG4476	Belongs to the UPF0223 family
CEB40_RS09050	COG0039	L-malate dehydrogenase activity
CEB40_RS09075	COG0242	peptide deformylase activity
CEB40_RS09085	COG5503	Protein of unknown function (DUF1447)
CEB40_RS09090	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
CEB40_RS09095	COG1597	lipid kinase activity
CEB40_RS09105	COG3584	3D domain protein
CEB40_RS09105	COG1388	LysM domain
CEB40_RS09110	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CEB40_RS09115	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CEB40_RS09145	COG0569	domain protein
CEB40_RS09150	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CEB40_RS09155	COG0482	sulfurtransferase activity
CEB40_RS09165	COG1104	cysteine desulfurase activity
CEB40_RS09170	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CEB40_RS09180	COG0494	nUDIX hydrolase
CEB40_RS09185	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
CEB40_RS09190	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
CEB40_RS09195	COG3599	regulation of cell shape
CEB40_RS09205	COG0762	integral membrane protein
CEB40_RS09210	COG1799	cell septum assembly
CEB40_RS09225	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
CEB40_RS09230	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CEB40_RS09235	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
CEB40_RS09240	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CEB40_RS09245	COG0768	penicillin binding
CEB40_RS09255	COG0275	rRNA processing
CEB40_RS09260	COG2001	Belongs to the MraZ family
CEB40_RS09275	COG2826	transposase and inactivated derivatives, IS30 family
CEB40_RS09285	COG1674	ftsk spoiiie
CEB40_RS09290	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
CEB40_RS09300	COG1114	Component of the transport system for branched-chain amino acids
CEB40_RS09315	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
CEB40_RS09320	COG0628	permease
CEB40_RS09330	COG2706	6-phosphogluconolactonase activity
CEB40_RS09335	COG3142	Participates in the control of copper homeostasis
CEB40_RS09340	COG0564	pseudouridine synthase activity
CEB40_RS09345	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CEB40_RS09350	COG2357	RelA SpoT domain protein
CEB40_RS09360	COG1164	Oligoendopeptidase f
CEB40_RS09370	COG4862	establishment of competence for transformation
CEB40_RS09375	COG1393	Belongs to the ArsC family
CEB40_RS09380	COG1234	tRNA 3'-trailer cleavage
CEB40_RS09520	COG1098	S1 RNA binding domain
CEB40_RS09530	COG0586	Pfam SNARE associated Golgi protein
CEB40_RS09540	COG0647	UMP catabolic process
CEB40_RS09545	COG4470	Protein conserved in bacteria
CEB40_RS09550	COG0737	Belongs to the 5'-nucleotidase family
CEB40_RS09560	COG1113	amino acid transport
CEB40_RS09565	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CEB40_RS09570	COG0827	DNA restriction-modification system
CEB40_RS09600	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CEB40_RS09610	COG0217	transcriptional regulatory protein
CEB40_RS09625	COG1609	Transcriptional regulator
CEB40_RS09630	COG0006	proline dipeptidase activity
CEB40_RS09635	COG0789	Transcriptional regulator
CEB40_RS09655	COG0668	transmembrane transport
CEB40_RS09660	COG1473	amidohydrolase
CEB40_RS09665	COG2171	N-acyltransferase activity
CEB40_RS09670	COG0517	IMP dehydrogenase activity
CEB40_RS09680	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
CEB40_RS09685	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
CEB40_RS09690	COG1719	4-vinyl reductase, 4VR
CEB40_RS09695	COG3118	belongs to the thioredoxin family
CEB40_RS09700	COG1193	negative regulation of DNA recombination
CEB40_RS09710	COG3906	Belongs to the UPF0473 family
CEB40_RS09715	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
CEB40_RS09720	COG4472	Bacterial protein of unknown function (DUF965)
CEB40_RS09725	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CEB40_RS09730	COG0513	Belongs to the DEAD box helicase family
CEB40_RS09735	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
CEB40_RS09740	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CEB40_RS09745	COG1862	Preprotein translocase
CEB40_RS09750	COG0343	queuine tRNA-ribosyltransferase activity
CEB40_RS09755	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
CEB40_RS09760	COG2255	four-way junction helicase activity
CEB40_RS09765	COG0632	four-way junction helicase activity
CEB40_RS09790	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
CEB40_RS09795	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
CEB40_RS09800	COG1692	metallophosphoesterase
CEB40_RS09805	COG1418	mRNA catabolic process
CEB40_RS09810	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
CEB40_RS09815	COG1058	Belongs to the CinA family
CEB40_RS09815	COG1546	Belongs to the CinA family
CEB40_RS09820	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CEB40_RS09825	COG1426	Protein conserved in bacteria
CEB40_RS09830	COG0612	Peptidase, M16
CEB40_RS09835	COG0612	Peptidase, M16
CEB40_RS09840	COG0527	aspartate kinase activity
CEB40_RS09850	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CEB40_RS09855	COG1126	abc transporter atp-binding protein
CEB40_RS09860	COG0765	amino acid transport
CEB40_RS09865	COG2894	cell division
CEB40_RS09870	COG0850	regulation of cytokinetic process
CEB40_RS09880	COG1792	Involved in formation and maintenance of cell shape
CEB40_RS09885	COG1077	Cell shape determining protein MreB Mrl
CEB40_RS09890	COG2003	Belongs to the UPF0758 family
CEB40_RS09895	COG0285	dihydrofolate synthase activity
CEB40_RS09900	COG0525	valine-tRNA ligase activity
CEB40_RS09910	COG1181	Belongs to the D-alanine--D-alanine ligase family
CEB40_RS09910	COG2918	glutathione biosynthetic process
CEB40_RS09915	COG0301	tRNA thio-modification
CEB40_RS09920	COG1104	cysteine desulfurase activity
CEB40_RS09925	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
CEB40_RS09930	COG1956	GAF domain-containing protein
CEB40_RS09935	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
CEB40_RS09940	COG4493	Belongs to the UPF0637 family
CEB40_RS09960	COG0189	ligase activity
CEB40_RS09960	COG2918	glutathione biosynthetic process
CEB40_RS09965	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CEB40_RS09980	COG0589	response to stress
CEB40_RS10000	COG1181	Belongs to the D-alanine--D-alanine ligase family
CEB40_RS10020	COG1464	Belongs to the NlpA lipoprotein family
CEB40_RS10025	COG2011	ABC-type metal ion transport system permease component
CEB40_RS10030	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CEB40_RS10035	COG0509	glycine decarboxylation via glycine cleavage system
CEB40_RS10040	COG0772	Belongs to the SEDS family
CEB40_RS10050	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
CEB40_RS10055	COG1077	Cell shape determining protein MreB Mrl
CEB40_RS10065	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CEB40_RS10070	COG0355	proton-transporting ATP synthase activity, rotational mechanism
CEB40_RS10075	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
CEB40_RS10080	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
CEB40_RS10085	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
CEB40_RS10090	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CEB40_RS10095	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
CEB40_RS10100	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CEB40_RS10105	COG0356	it plays a direct role in the translocation of protons across the membrane
CEB40_RS10110	COG2233	PERMEase
CEB40_RS10120	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
CEB40_RS10125	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
CEB40_RS10130	COG0009	L-threonylcarbamoyladenylate synthase
CEB40_RS10135	COG2890	protein-(glutamine-N5) methyltransferase activity
CEB40_RS10140	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
CEB40_RS10145	COG1435	thymidine kinase activity
CEB40_RS10150	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
CEB40_RS10155	COG3442	glutamine amidotransferase
CEB40_RS10160	COG1482	cell wall glycoprotein biosynthetic process
CEB40_RS10165	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CEB40_RS10175	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CEB40_RS10190	COG1132	(ABC) transporter
CEB40_RS10205	COG0726	polysaccharide deacetylase
CEB40_RS10340	COG2868	ribosomal protein
CEB40_RS10395	COG0270	DNA (cytosine-5-)-methyltransferase activity
CEB40_RS10480	COG1396	sequence-specific DNA binding
CEB40_RS10570	COG4886	Leucine-rich repeat (LRR) protein
CEB40_RS10570	COG4932	domain protein
CEB40_RS10615	COG1132	(ABC) transporter
CEB40_RS10625	COG0577	efflux transmembrane transporter activity
CEB40_RS10625	COG1136	(ABC) transporter
CEB40_RS10635	COG0166	Belongs to the GPI family
CEB40_RS10640	COG4975	Glucose uptake
CEB40_RS10645	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
CEB40_RS10650	COG3850	Histidine kinase
CEB40_RS10650	COG5002	protein histidine kinase activity
CEB40_RS10655	COG0745	RESPONSE REGULATOR receiver
CEB40_RS10660	COG2848	UPF0210 protein
CEB40_RS10665	COG3830	Belongs to the UPF0237 family
CEB40_RS10690	COG0477	Major facilitator Superfamily
CEB40_RS10710	COG0791	NLP P60 protein
CEB40_RS10715	COG1522	sequence-specific DNA binding
CEB40_RS10735	COG0488	(ABC) transporter
CEB40_RS10755	COG1263	PTS System
CEB40_RS10755	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CEB40_RS10755	COG2190	(PTS) system
CEB40_RS10760	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CEB40_RS10765	COG1307	EDD domain protein, DegV family
CEB40_RS10775	COG2873	o-acetylhomoserine
CEB40_RS10780	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
CEB40_RS10790	COG4120	Belongs to the binding-protein-dependent transport system permease family
CEB40_RS10800	COG0446	pyridine nucleotide-disulphide oxidoreductase
CEB40_RS10805	COG2084	Dehydrogenase
CEB40_RS10815	COG0110	maltose O-acetyltransferase activity
CEB40_RS10820	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CEB40_RS10825	COG0140	phosphoribosyl-ATP diphosphatase activity
CEB40_RS10830	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
CEB40_RS10835	COG0107	imidazoleglycerol-phosphate synthase activity
CEB40_RS10840	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
CEB40_RS10845	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
CEB40_RS10850	COG0131	Imidazoleglycerol-phosphate dehydratase
CEB40_RS10855	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
CEB40_RS10860	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
CEB40_RS10865	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
CEB40_RS10870	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
CEB40_RS10895	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CEB40_RS10910	COG3548	integral membrane protein
CEB40_RS10930	COG1368	sulfuric ester hydrolase activity
CEB40_RS10935	COG0584	glycerophosphoryl diester phosphodiesterase
CEB40_RS10940	COG0492	ferredoxin-NADP+ reductase activity
CEB40_RS10950	COG4932	domain protein
CEB40_RS10955	COG2326	polyphosphate kinase activity
CEB40_RS10960	COG0778	Nitroreductase
CEB40_RS10970	COG0328	RNA-DNA hybrid ribonuclease activity
CEB40_RS10975	COG4975	Glucose uptake
CEB40_RS10990	COG1349	DNA-binding transcription factor activity
CEB40_RS10995	COG1882	Formate acetyltransferase
CEB40_RS11015	COG1609	Transcriptional regulator
CEB40_RS11020	COG1737	Transcriptional regulator
CEB40_RS11025	COG0673	inositol 2-dehydrogenase activity
CEB40_RS11030	COG0673	inositol 2-dehydrogenase activity
CEB40_RS11035	COG0025	NhaP-type Na H and K H
CEB40_RS11040	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
CEB40_RS11045	COG1335	isochorismatase
CEB40_RS11055	COG1131	(ABC) transporter
CEB40_RS11060	COG1725	Transcriptional regulator
CEB40_RS11105	COG0028	Belongs to the TPP enzyme family
CEB40_RS11115	COG1073	alpha beta
CEB40_RS11120	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CEB40_RS11125	COG0626	cystathionine gamma-synthase activity
CEB40_RS11155	COG0095	Lipoate-protein ligase
CEB40_RS11160	COG1705	Flagellar rod assembly protein muramidase FlgJ
CEB40_RS11170	COG3716	PTS system mannose fructose sorbose family IID component
CEB40_RS11175	COG3715	PTS system
CEB40_RS11180	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CEB40_RS11185	COG2188	Transcriptional regulator
CEB40_RS11190	COG0589	response to stress
CEB40_RS11195	COG0564	pseudouridine synthase activity
CEB40_RS11210	COG4640	response to antibiotic
CEB40_RS11215	COG1396	sequence-specific DNA binding
CEB40_RS11230	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
CEB40_RS11240	COG2188	Transcriptional regulator
CEB40_RS11245	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CEB40_RS11255	COG1418	mRNA catabolic process
CEB40_RS11285	COG1253	flavin adenine dinucleotide binding
CEB40_RS11290	COG1780	Probably involved in ribonucleotide reductase function
CEB40_RS11295	COG0025	NhaP-type Na H and K H
CEB40_RS11300	COG2814	Major facilitator Superfamily
CEB40_RS11305	COG0789	Transcriptional regulator
CEB40_RS11310	COG0604	alcohol dehydrogenase
CEB40_RS11320	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
CEB40_RS11325	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CEB40_RS11330	COG0436	Aminotransferase
CEB40_RS11335	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CEB40_RS11350	COG0583	DNA-binding transcription factor activity
CEB40_RS11355	COG0702	epimerase
CEB40_RS11370	COG1074	ATP-dependent DNA helicase activity
CEB40_RS11375	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
CEB40_RS11385	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
CEB40_RS11390	COG0284	orotidine-5'-phosphate decarboxylase activity
CEB40_RS11395	COG0167	dihydroorotate dehydrogenase activity
CEB40_RS11405	COG0505	Belongs to the CarA family
CEB40_RS11410	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
CEB40_RS11415	COG0540	Belongs to the ATCase OTCase family
CEB40_RS11420	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
CEB40_RS11425	COG2508	Transcriptional regulator
CEB40_RS11430	COG2233	PERMEase
CEB40_RS11435	COG2252	PERMEase
CEB40_RS11465	COG0151	Belongs to the GarS family
CEB40_RS11470	COG0138	bifunctional purine biosynthesis protein purh
CEB40_RS11475	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
CEB40_RS11480	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
CEB40_RS11490	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CEB40_RS11495	COG0047	phosphoribosylformylglycinamidine synthase activity
CEB40_RS11500	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CEB40_RS11505	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
CEB40_RS11510	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
CEB40_RS11520	COG0431	NADPH-dependent FMN reductase
CEB40_RS11520	COG1053	succinate dehydrogenase
CEB40_RS11520	COG3976	FMN-binding domain protein
CEB40_RS11525	COG0431	NADPH-dependent FMN reductase
CEB40_RS11525	COG1053	succinate dehydrogenase
CEB40_RS11525	COG3976	FMN-binding domain protein
CEB40_RS11530	COG0095	Lipoate-protein ligase
CEB40_RS11535	COG2365	Tyrosine phosphatase family
CEB40_RS11555	COG1136	(ABC) transporter
CEB40_RS11570	COG1725	Transcriptional regulator
CEB40_RS11575	COG1131	(ABC) transporter
CEB40_RS11585	COG0589	response to stress
CEB40_RS11595	COG2246	polysaccharide biosynthetic process
CEB40_RS11615	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
CEB40_RS11635	COG0366	Alpha amylase catalytic
CEB40_RS11645	COG0561	phosphatase activity
CEB40_RS11655	COG0110	maltose O-acetyltransferase activity
CEB40_RS11660	COG0494	nUDIX hydrolase
CEB40_RS11700	COG1827	regulation of RNA biosynthetic process
CEB40_RS11705	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
CEB40_RS11710	COG1309	transcriptional regulator
CEB40_RS11720	COG1131	(ABC) transporter
CEB40_RS11725	COG3048	D-serine ammonia-lyase activity
CEB40_RS11730	COG2723	6-phospho-beta-galactosidase activity
CEB40_RS11735	COG2723	6-phospho-beta-galactosidase activity
CEB40_RS11740	COG1447	Phosphotransferase system cellobiose-specific component IIA
CEB40_RS11745	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CEB40_RS11750	COG2188	Transcriptional regulator
CEB40_RS11755	COG1216	Glycosyl transferase, family 2
CEB40_RS11770	COG0561	phosphatase activity
CEB40_RS11775	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CEB40_RS11800	COG0716	FMN binding
CEB40_RS11820	COG0710	3-dehydroquinate dehydratase activity
CEB40_RS11825	COG0531	amino acid
CEB40_RS11870	COG4720	Psort location CytoplasmicMembrane, score
CEB40_RS11875	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CEB40_RS11890	COG4990	cell redox homeostasis
CEB40_RS11905	COG1811	Na channel or pump
CEB40_RS11910	COG4978	Transcriptional regulator
CEB40_RS11910	COG0789	Transcriptional regulator
CEB40_RS11930	COG0577	efflux transmembrane transporter activity
CEB40_RS11935	COG1136	(ABC) transporter
CEB40_RS11985	COG2814	Major facilitator Superfamily
CEB40_RS11995	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CEB40_RS12000	COG2855	membrane
CEB40_RS12005	COG0583	DNA-binding transcription factor activity
CEB40_RS12015	COG0438	transferase activity, transferring glycosyl groups
CEB40_RS12035	COG2169	Transcriptional regulator
CEB40_RS12040	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CEB40_RS12050	COG4152	abc transporter atp-binding protein
CEB40_RS12075	COG0789	Transcriptional regulator
CEB40_RS12095	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CEB40_RS12120	COG0456	acetyltransferase
CEB40_RS12145	COG0583	DNA-binding transcription factor activity
CEB40_RS12155	COG1063	alcohol dehydrogenase
CEB40_RS12160	COG1028	Short-chain dehydrogenase reductase Sdr
CEB40_RS12170	COG0589	response to stress
CEB40_RS12175	COG0110	maltose O-acetyltransferase activity
CEB40_RS12180	COG1011	Hydrolase
CEB40_RS12195	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
CEB40_RS12205	COG0667	Aldo Keto reductase
CEB40_RS12210	COG1132	(ABC) transporter
CEB40_RS12215	COG1132	(ABC) transporter
CEB40_RS12220	COG2814	Major facilitator Superfamily
CEB40_RS12240	COG1511	domain protein
CEB40_RS12240	COG1511	domain protein
CEB40_RS12250	COG0640	Transcriptional regulator
CEB40_RS12280	COG0488	(ABC) transporter
CEB40_RS12285	COG0561	phosphatase activity
CEB40_RS12295	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CEB40_RS12310	COG2267	carboxylic ester hydrolase activity
CEB40_RS12315	COG0531	amino acid
CEB40_RS12320	COG2270	Major facilitator Superfamily
CEB40_RS12360	COG2200	EAL domain
CEB40_RS12370	COG1328	CTP reductase activity
CEB40_RS12380	COG0242	peptide deformylase activity
CEB40_RS12390	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CEB40_RS12405	COG0583	DNA-binding transcription factor activity
CEB40_RS12415	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
CEB40_RS12470	COG0697	spore germination
CEB40_RS12510	COG1131	(ABC) transporter
CEB40_RS12540	COG3279	Response regulator of the LytR AlgR family
CEB40_RS12550	COG1940	carbohydrate kinase activity
CEB40_RS12555	COG1132	(ABC) transporter
CEB40_RS12565	COG0778	Nitroreductase
CEB40_RS12570	COG2190	(PTS) system
CEB40_RS12570	COG1263	PTS System
CEB40_RS12570	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CEB40_RS12575	COG1116	anion transmembrane transporter activity
CEB40_RS12610	COG3620	sequence-specific DNA binding
CEB40_RS12610	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
CEB40_RS12610	COG0617	tRNA 3'-terminal CCA addition
CEB40_RS12615	COG0410	ABC transporter
CEB40_RS12630	COG0559	Belongs to the binding-protein-dependent transport system permease family
CEB40_RS12645	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CEB40_RS12645	COG5549	protein import
CEB40_RS12650	COG2246	polysaccharide biosynthetic process
CEB40_RS12660	COG1914	H( )-stimulated, divalent metal cation uptake system
CEB40_RS12680	COG0640	Transcriptional regulator
CEB40_RS12690	COG0577	efflux transmembrane transporter activity
CEB40_RS12690	COG1136	(ABC) transporter
CEB40_RS12725	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CEB40_RS12730	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CEB40_RS12735	COG2723	6-phospho-beta-galactosidase activity
CEB40_RS12745	COG0789	Transcriptional regulator
CEB40_RS12750	COG0741	lytic transglycosylase activity
CEB40_RS12770	COG0803	Belongs to the bacterial solute-binding protein 9 family
CEB40_RS12795	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CEB40_RS12805	COG1132	(ABC) transporter
CEB40_RS12810	COG1132	(ABC) transporter
CEB40_RS12815	COG1473	amidohydrolase
CEB40_RS12820	COG1028	Short-chain dehydrogenase reductase Sdr
CEB40_RS12835	COG0531	amino acid
CEB40_RS12855	COG2217	Heavy metal translocating P-type atpase
CEB40_RS12910	COG1063	alcohol dehydrogenase
CEB40_RS12950	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CEB40_RS12955	COG1733	regulation of RNA biosynthetic process
CEB40_RS12960	COG2814	Major facilitator Superfamily
CEB40_RS12970	COG0367	asparagine synthase
CEB40_RS12975	COG3279	Response regulator of the LytR AlgR family
CEB40_RS12990	COG1309	transcriptional regulator
CEB40_RS13000	COG1012	belongs to the aldehyde dehydrogenase family
CEB40_RS13015	COG1733	regulation of RNA biosynthetic process
CEB40_RS13020	COG0300	oxidoreductase activity
CEB40_RS13040	COG0667	Aldo Keto reductase
CEB40_RS13045	COG0477	Major facilitator Superfamily
CEB40_RS13055	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CEB40_RS13060	COG1120	ATPase activity
CEB40_RS13065	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CEB40_RS13070	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CEB40_RS13075	COG1309	transcriptional regulator
CEB40_RS13085	COG4221	oxidoreductase activity
CEB40_RS13090	COG0110	maltose O-acetyltransferase activity
CEB40_RS13095	COG1028	Short-chain dehydrogenase reductase Sdr
CEB40_RS13130	COG0481	GTPase activity
CEB40_RS13140	COG2816	NAD+ diphosphatase activity
CEB40_RS13160	COG0783	Belongs to the Dps family
CEB40_RS13170	COG2723	6-phospho-beta-galactosidase activity
CEB40_RS13175	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CEB40_RS13190	COG0789	Transcriptional regulator
CEB40_RS13215	COG1733	regulation of RNA biosynthetic process
CEB40_RS13225	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
CEB40_RS13250	COG1376	ErfK ybiS ycfS ynhG family protein
CEB40_RS13260	COG0588	phosphoglycerate mutase activity
CEB40_RS13265	COG0628	permease
CEB40_RS13270	COG1940	carbohydrate kinase activity
CEB40_RS13270	COG1846	Transcriptional regulator
CEB40_RS13280	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CEB40_RS13330	COG1247	-acetyltransferase
CEB40_RS13335	COG1686	Belongs to the peptidase S11 family
CEB40_RS13355	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CEB40_RS13360	COG0517	IMP dehydrogenase activity
CEB40_RS13360	COG0516	GMP reductase activity
CEB40_RS13370	COG0012	GTP binding
CEB40_RS13375	COG4481	Protein conserved in bacteria
CEB40_RS13380	COG1475	DNA binding
CEB40_RS13385	COG1192	Involved in chromosome partitioning
CEB40_RS13395	COG0357	Ribosomal RNA small subunit methyltransferase G
CEB40_RS13400	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CEB40_RS13415	COG0583	DNA-binding transcription factor activity
CEB40_RS13420	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CEB40_RS13425	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CEB40_RS13430	COG0765	amino acid transport
CEB40_RS13435	COG1126	abc transporter atp-binding protein
CEB40_RS13440	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CEB40_RS13465	COG1263	PTS System
CEB40_RS13465	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CEB40_RS13465	COG2190	(PTS) system
CEB40_RS13470	COG0366	Alpha amylase catalytic
CEB40_RS13475	COG1609	Transcriptional regulator
CEB40_RS13485	COG0390	transport system, permease component
CEB40_RS13490	COG4619	ABC transporter
CEB40_RS13495	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CEB40_RS13510	COG1263	PTS System
CEB40_RS13510	COG2190	(PTS) system
CEB40_RS13510	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CEB40_RS13525	COG0583	DNA-binding transcription factor activity
CEB40_RS13535	COG0561	phosphatase activity
CEB40_RS13545	COG0383	alpha-mannosidase activity
CEB40_RS13550	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CEB40_RS13550	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CEB40_RS13550	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CEB40_RS13555	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CEB40_RS13560	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CEB40_RS13560	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CEB40_RS13560	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CEB40_RS13565	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CEB40_RS13565	COG3711	transcriptional antiterminator
CEB40_RS13580	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CEB40_RS13580	COG1263	PTS System
CEB40_RS13580	COG2190	(PTS) system
CEB40_RS13610	COG0735	belongs to the Fur family
CEB40_RS13635	COG1380	Effector of murein hydrolase LrgA
CEB40_RS13645	COG1307	EDD domain protein, DegV family
CEB40_RS13655	COG2738	Putative neutral zinc metallopeptidase
CEB40_RS13665	COG1562	ergosterol biosynthetic process
CEB40_RS13675	COG1929	Belongs to the glycerate kinase type-1 family
CEB40_RS13690	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CEB40_RS13695	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
CEB40_RS13700	COG0516	GMP reductase activity
CEB40_RS13705	COG2365	Tyrosine phosphatase family
CEB40_RS13710	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CEB40_RS13720	COG0531	amino acid
CEB40_RS13725	COG3158	transport of potassium into the cell
CEB40_RS13730	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
CEB40_RS13735	COG0628	permease
CEB40_RS13740	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
CEB40_RS13755	COG1272	protein, Hemolysin III
CEB40_RS13760	COG0640	Transcriptional regulator
CEB40_RS13785	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
CEB40_RS13795	COG0302	gtp cyclohydrolase
CEB40_RS13800	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CEB40_RS13815	COG0803	Belongs to the bacterial solute-binding protein 9 family
CEB40_RS13820	COG2814	Major facilitator Superfamily
CEB40_RS13850	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CEB40_RS13855	COG1882	Formate acetyltransferase
CEB40_RS13860	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
CEB40_RS13865	COG2151	metal-sulfur cluster biosynthetic enzyme
CEB40_RS13870	COG4989	oxidoreductase activity
CEB40_RS13900	COG2217	Heavy metal translocating P-type atpase
CEB40_RS13910	COG2315	Protein conserved in bacteria
CEB40_RS13920	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
CEB40_RS13925	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CEB40_RS13935	COG1757	Na H antiporter
CEB40_RS13940	COG1113	amino acid transport
CEB40_RS13950	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
CEB40_RS13965	COG1393	Belongs to the ArsC family
CEB40_RS13970	COG3189	MarR family transcriptional regulator
CEB40_RS13980	COG1194	a g-specific adenine glycosylase
CEB40_RS13995	COG0071	Belongs to the small heat shock protein (HSP20) family
CEB40_RS14015	COG0697	spore germination
CEB40_RS14030	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
CEB40_RS14055	COG0477	Major facilitator Superfamily
CEB40_RS14115	COG0737	Belongs to the 5'-nucleotidase family
CEB40_RS14125	COG0656	L-ascorbic acid biosynthetic process
CEB40_RS14165	COG1968	undecaprenyl-diphosphatase activity
CEB40_RS14170	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
CEB40_RS14205	COG2207	Transcriptional regulator
CEB40_RS14230	COG0076	glutamate decarboxylase activity
CEB40_RS14285	COG1309	transcriptional regulator
CEB40_RS14295	COG2226	methyltransferase
CEB40_RS14310	COG2217	Heavy metal translocating P-type atpase
CEB40_RS14315	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
CEB40_RS14320	COG3118	belongs to the thioredoxin family
CEB40_RS14325	COG1937	Protein conserved in bacteria
CEB40_RS14345	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CEB40_RS14350	COG3590	peptidase
CEB40_RS14360	COG0446	pyridine nucleotide-disulphide oxidoreductase
CEB40_RS14410	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
CEB40_RS14420	COG1114	Component of the transport system for branched-chain amino acids
CEB40_RS14430	COG1874	Beta-galactosidase
CEB40_RS14435	COG1609	Transcriptional regulator
CEB40_RS14445	COG0477	Major facilitator Superfamily
CEB40_RS14465	COG2184	nucleotidyltransferase activity
CEB40_RS14470	COG2944	sequence-specific DNA binding
CEB40_RS14475	COG1609	Transcriptional regulator
CEB40_RS14480	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
CEB40_RS14485	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CEB40_RS14490	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
CEB40_RS14510	COG2211	Major facilitator Superfamily
CEB40_RS14510	COG2190	(PTS) system
CEB40_RS14515	COG2017	converts alpha-aldose to the beta-anomer
CEB40_RS14520	COG1609	Transcriptional regulator
CEB40_RS14525	COG0667	Aldo Keto reductase
CEB40_RS14545	COG0710	3-dehydroquinate dehydratase activity
CEB40_RS14550	COG0738	Major facilitator superfamily
CEB40_RS14555	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CEB40_RS14560	COG0583	DNA-binding transcription factor activity
CEB40_RS14565	COG0738	Major facilitator superfamily
CEB40_RS14575	COG2267	carboxylic ester hydrolase activity
CEB40_RS14580	COG2188	Transcriptional regulator
CEB40_RS14585	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CEB40_RS14590	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
CEB40_RS14595	COG2971	BadF BadG BcrA BcrD
CEB40_RS14605	COG2723	6-phospho-beta-galactosidase activity
CEB40_RS14615	COG3711	transcriptional antiterminator
CEB40_RS14620	COG2723	6-phospho-beta-galactosidase activity
CEB40_RS14625	COG2723	6-phospho-beta-galactosidase activity
CEB40_RS14630	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CEB40_RS14630	COG1263	PTS System
CEB40_RS14630	COG2190	(PTS) system
CEB40_RS14650	COG2211	Major facilitator Superfamily
CEB40_RS14665	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
CEB40_RS14680	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CEB40_RS14700	COG3711	transcriptional antiterminator
CEB40_RS14715	COG3775	system Galactitol-specific IIC component
CEB40_RS14720	COG3414	Phosphotransferase system galactitol-specific IIB component
CEB40_RS14730	COG1349	DNA-binding transcription factor activity
CEB40_RS14735	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
CEB40_RS14745	COG0110	maltose O-acetyltransferase activity
CEB40_RS14750	COG2160	L-arabinose isomerase activity
CEB40_RS14770	COG1609	Transcriptional regulator
CEB40_RS14775	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
CEB40_RS14800	COG2261	transglycosylase associated protein
CEB40_RS14810	COG1393	Belongs to the ArsC family
CEB40_RS14830	COG4512	PFAM Accessory gene regulator B
CEB40_RS14845	COG1304	FMN binding
CEB40_RS14850	COG0028	Belongs to the TPP enzyme family
CEB40_RS14855	COG1959	2 iron, 2 sulfur cluster binding
CEB40_RS14860	COG0028	Belongs to the TPP enzyme family
CEB40_RS14875	COG0235	Class ii aldolase
CEB40_RS14880	COG4806	L-rhamnose isomerase
CEB40_RS14885	COG3254	rhamnose metabolic process
CEB40_RS14890	COG1070	Carbohydrate kinase
CEB40_RS14895	COG2814	Major facilitator Superfamily
CEB40_RS14900	COG2207	Transcriptional regulator
CEB40_RS14905	COG1349	DNA-binding transcription factor activity
CEB40_RS14920	COG3775	system Galactitol-specific IIC component
CEB40_RS14935	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CEB40_RS14935	COG2190	(PTS) system
CEB40_RS14935	COG1263	PTS System
CEB40_RS14955	COG1737	Transcriptional regulator
CEB40_RS14960	COG1263	PTS System
CEB40_RS14960	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CEB40_RS14980	COG1263	PTS System
CEB40_RS14980	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CEB40_RS14990	COG1609	Transcriptional regulator
CEB40_RS15000	COG0366	Alpha amylase catalytic
CEB40_RS15015	COG2723	6-phospho-beta-galactosidase activity
CEB40_RS15020	COG1940	carbohydrate kinase activity
CEB40_RS15025	COG0383	alpha-mannosidase activity
CEB40_RS15035	COG2188	Transcriptional regulator
CEB40_RS15050	COG3842	ATPase activity
CEB40_RS15060	COG2207	Transcriptional regulator
CEB40_RS15060	COG4753	response regulator
CEB40_RS15065	COG2972	Histidine kinase
CEB40_RS15075	COG0366	Alpha amylase catalytic
CEB40_RS15080	COG1653	transport
CEB40_RS15085	COG0395	ABC-type sugar transport system, permease component
CEB40_RS15100	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CEB40_RS15100	COG2207	Transcriptional regulator
CEB40_RS15105	COG1132	(ABC) transporter
CEB40_RS15110	COG1132	(ABC) transporter
CEB40_RS15115	COG2188	Transcriptional regulator
CEB40_RS15130	COG3732	PTS system glucitol sorbitol-specific
CEB40_RS15135	COG3730	PTS system glucitol sorbitol-specific
CEB40_RS15155	COG4975	Glucose uptake
CEB40_RS15160	COG1869	D-ribose catabolic process
CEB40_RS15170	COG1609	Transcriptional regulator
CEB40_RS15175	COG1454	alcohol dehydrogenase
CEB40_RS15175	COG1012	belongs to the aldehyde dehydrogenase family
CEB40_RS15185	COG1695	Transcriptional regulator
CEB40_RS15190	COG3479	Phenolic acid decarboxylase
CEB40_RS15205	COG1307	EDD domain protein, DegV family
CEB40_RS15250	COG0445	tRNA wobble uridine modification
CEB40_RS15255	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
CEB40_RS15260	COG1847	R3H domain protein
CEB40_RS15270	COG4166	transmembrane transport
CEB40_RS15275	COG0706	membrane insertase activity
CEB40_RS15280	COG0594	ribonuclease P activity
CEB40_RS15285	COG0230	Belongs to the bacterial ribosomal protein bL34 family
CEB40_RS15290	COG0366	Alpha amylase catalytic
CEB40_RS15300	COG1192	Involved in chromosome partitioning
CEB40_RS15315	COG3328	transposase activity
CEB40_RS15335	COG1175	transmembrane transport
CEB40_RS15340	COG0395	ABC-type sugar transport system, permease component
CEB40_RS15350	COG0584	glycerophosphoryl diester phosphodiesterase
CEB40_RS15365	COG1846	Transcriptional regulator
CEB40_RS15375	COG3158	transport of potassium into the cell
CEB40_RS15380	COG0745	RESPONSE REGULATOR receiver
CEB40_RS15385	COG2205	protein histidine kinase activity
CEB40_RS15390	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
CEB40_RS15395	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
CEB40_RS15425	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CEB40_RS15470	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CEB40_RS15495	COG0551	DNA topoisomerase type I activity
CEB40_RS15495	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CEB40_RS15545	COG0561	phosphatase activity
CEB40_RS15550	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CEB40_RS15555	COG1554	hydrolase, family 65, central catalytic
CEB40_RS15575	COG2801	Transposase and inactivated derivatives
CEB40_RS15585	COG0562	UDP-galactopyranose mutase
CEB40_RS15605	COG0028	Belongs to the TPP enzyme family
CEB40_RS15625	COG2261	transglycosylase associated protein
CEB40_RS15630	COG2814	Major facilitator Superfamily
CEB40_RS15635	COG5039	Polysaccharide pyruvyl transferase
CEB40_RS15640	COG2814	Major facilitator Superfamily
CEB40_RS15645	COG2801	Transposase and inactivated derivatives
CEB40_RS15660	COG4876	unkown
CEB40_RS15670	COG4716	Myosin-crossreactive antigen
CEB40_RS15685	COG2826	transposase and inactivated derivatives, IS30 family
CEB40_RS15695	COG0693	protein deglycase activity
CEB40_RS15700	COG1846	Transcriptional regulator
CEB40_RS15725	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CEB40_RS15755	COG2826	transposase and inactivated derivatives, IS30 family
CEB40_RS15760	COG1388	LysM domain
CEB40_RS15780	COG3328	transposase activity
CEB40_RS15805	COG1653	transport
CEB40_RS15810	COG3842	ATPase activity
CEB40_RS15815	COG1192	Involved in chromosome partitioning
CEB40_RS15855	COG0534	Mate efflux family protein