locus-tag	class	description
CBI37_RS00030	COG1388	LysM domain
CBI37_RS00030	COG3942	CHAP domain
CBI37_RS00045	COG1136	(ABC) transporter
CBI37_RS00045	COG0577	efflux transmembrane transporter activity
CBI37_RS00055	COG1132	(ABC) transporter
CBI37_RS00105	COG4932	domain protein
CBI37_RS00105	COG4886	Leucine-rich repeat (LRR) protein
CBI37_RS00175	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
CBI37_RS00185	COG1970	mechanosensitive ion channel activity
CBI37_RS00320	COG3728	DNA packaging
CBI37_RS00320	COG5484	DNA packaging
CBI37_RS00335	COG2868	ribosomal protein
CBI37_RS00455	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CBI37_RS00480	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CBI37_RS00490	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
CBI37_RS00500	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
CBI37_RS00505	COG0562	UDP-galactopyranose mutase
CBI37_RS00550	COG2244	polysaccharide biosynthetic process
CBI37_RS00555	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
CBI37_RS00565	COG1088	dTDP-glucose 4,6-dehydratase activity
CBI37_RS00570	COG0582	viral genome integration into host DNA
CBI37_RS00580	COG0489	protein tyrosine kinase activity
CBI37_RS00585	COG4464	protein tyrosine phosphatase activity
CBI37_RS00595	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CBI37_RS00605	COG0438	transferase activity, transferring glycosyl groups
CBI37_RS00620	COG5039	Polysaccharide pyruvyl transferase
CBI37_RS00720	COG0562	UDP-galactopyranose mutase
CBI37_RS00755	COG2207	Transcriptional regulator
CBI37_RS00755	COG1609	Transcriptional regulator
CBI37_RS00775	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CBI37_RS00810	COG2137	regulation of response to DNA damage stimulus
CBI37_RS00815	COG3557	Belongs to the UPF0374 family
CBI37_RS00835	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CBI37_RS00845	COG0628	permease
CBI37_RS00850	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
CBI37_RS00855	COG2610	gluconate transmembrane transporter activity
CBI37_RS00860	COG1070	Carbohydrate kinase
CBI37_RS00865	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
CBI37_RS00870	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CBI37_RS00875	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
CBI37_RS00905	COG4166	transmembrane transport
CBI37_RS00910	COG0601	transmembrane transport
CBI37_RS00915	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CBI37_RS00920	COG0444	Belongs to the ABC transporter superfamily
CBI37_RS00925	COG4608	Belongs to the ABC transporter superfamily
CBI37_RS00935	COG0582	viral genome integration into host DNA
CBI37_RS00940	COG0542	response to heat
CBI37_RS00960	COG0438	transferase activity, transferring glycosyl groups
CBI37_RS00965	COG0438	transferase activity, transferring glycosyl groups
CBI37_RS00975	COG1686	Belongs to the peptidase S11 family
CBI37_RS00980	COG0436	Aminotransferase
CBI37_RS00985	COG4703	Protein of unknown function (DUF1797)
CBI37_RS00990	COG1368	sulfuric ester hydrolase activity
CBI37_RS01080	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CBI37_RS01100	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
CBI37_RS01115	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
CBI37_RS01120	COG0833	amino acid
CBI37_RS01125	COG2040	homocysteine
CBI37_RS01130	COG0438	transferase activity, transferring glycosyl groups
CBI37_RS01140	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
CBI37_RS01145	COG0477	Major facilitator Superfamily
CBI37_RS01160	COG0438	transferase activity, transferring glycosyl groups
CBI37_RS01175	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
CBI37_RS01185	COG0495	leucyl-tRNA aminoacylation
CBI37_RS01190	COG2244	polysaccharide biosynthetic process
CBI37_RS01195	COG1187	pseudouridine synthase activity
CBI37_RS01200	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
CBI37_RS01205	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CBI37_RS01220	COG1175	transmembrane transport
CBI37_RS01225	COG0395	ABC-type sugar transport system, permease component
CBI37_RS01235	COG0584	glycerophosphoryl diester phosphodiesterase
CBI37_RS01240	COG1428	Deoxynucleoside kinase
CBI37_RS01245	COG1970	mechanosensitive ion channel activity
CBI37_RS01250	COG1511	domain protein
CBI37_RS01250	COG1511	domain protein
CBI37_RS01280	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CBI37_RS01285	COG0789	Transcriptional regulator
CBI37_RS01300	COG0561	phosphatase activity
CBI37_RS01320	COG3279	Response regulator of the LytR AlgR family
CBI37_RS01340	COG1846	Transcriptional regulator
CBI37_RS01355	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CBI37_RS01395	COG0646	methionine synthase
CBI37_RS01395	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
CBI37_RS01400	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
CBI37_RS01410	COG2046	Belongs to the sulfate adenylyltransferase family
CBI37_RS01415	COG0529	Catalyzes the synthesis of activated sulfate
CBI37_RS01420	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
CBI37_RS01430	COG3273	potassium ion transport
CBI37_RS01430	COG0471	metal ion transport
CBI37_RS01435	COG0534	Mate efflux family protein
CBI37_RS01455	COG2153	protein acetylation
CBI37_RS01460	COG0018	arginyl-trna synthetase
CBI37_RS01470	COG1136	(ABC) transporter
CBI37_RS01470	COG0577	efflux transmembrane transporter activity
CBI37_RS01490	COG1447	Phosphotransferase system cellobiose-specific component IIA
CBI37_RS01495	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CBI37_RS01500	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CBI37_RS01505	COG2723	6-phospho-beta-galactosidase activity
CBI37_RS01515	COG1376	ErfK ybiS ycfS ynhG family protein
CBI37_RS01520	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CBI37_RS01525	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CBI37_RS01535	COG0436	Aminotransferase
CBI37_RS01540	COG1438	arginine binding
CBI37_RS01550	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CBI37_RS01555	COG3679	Belongs to the UPF0342 family
CBI37_RS01560	COG0420	3'-5' exonuclease activity
CBI37_RS01565	COG4717	serine-type aminopeptidase activity
CBI37_RS01570	COG3481	metal-dependent phosphohydrolase, HD sub domain
CBI37_RS01585	COG0583	DNA-binding transcription factor activity
CBI37_RS01600	COG1053	succinate dehydrogenase
CBI37_RS01600	COG3976	FMN-binding domain protein
CBI37_RS01600	COG0431	NADPH-dependent FMN reductase
CBI37_RS01615	COG3850	Histidine kinase
CBI37_RS01615	COG5002	protein histidine kinase activity
CBI37_RS01620	COG0745	RESPONSE REGULATOR receiver
CBI37_RS01630	COG0463	Glycosyl transferase, family 2
CBI37_RS01635	COG0586	Pfam SNARE associated Golgi protein
CBI37_RS01640	COG0463	Glycosyl transferase, family 2
CBI37_RS01660	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CBI37_RS01660	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CBI37_RS01665	COG0307	riboflavin synthase, alpha
CBI37_RS01670	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CBI37_RS01670	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CBI37_RS01675	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
CBI37_RS01690	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CBI37_RS01700	COG0446	pyridine nucleotide-disulphide oxidoreductase
CBI37_RS01730	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CBI37_RS01740	COG0537	adenosine 5'-monophosphoramidase activity
CBI37_RS01745	COG1131	(ABC) transporter
CBI37_RS01750	COG4473	ABC transporter
CBI37_RS01755	COG0510	thiamine kinase activity
CBI37_RS01760	COG0220	tRNA (guanine-N7-)-methyltransferase activity
CBI37_RS01770	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CBI37_RS01775	COG1674	ftsk spoiiie
CBI37_RS01780	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CBI37_RS01805	COG0719	Fe-S assembly protein
CBI37_RS01810	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CBI37_RS01820	COG0719	Fe-S assembly protein
CBI37_RS01825	COG2151	metal-sulfur cluster biosynthetic enzyme
CBI37_RS01840	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CBI37_RS01840	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CBI37_RS01845	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
CBI37_RS01850	COG0237	dephospho-CoA kinase activity
CBI37_RS01855	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
CBI37_RS01860	COG3611	Membrane attachment protein
CBI37_RS01865	COG1484	DNA-dependent DNA replication
CBI37_RS01870	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
CBI37_RS01875	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
CBI37_RS01880	COG0291	Belongs to the bacterial ribosomal protein bL35 family
CBI37_RS01885	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
CBI37_RS01895	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CBI37_RS01900	COG0604	alcohol dehydrogenase
CBI37_RS01905	COG1733	regulation of RNA biosynthetic process
CBI37_RS01915	COG1215	transferase activity, transferring glycosyl groups
CBI37_RS01930	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
CBI37_RS01935	COG1534	Rna-binding protein
CBI37_RS01940	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
CBI37_RS01945	COG1713	HD superfamily hydrolase involved in NAD metabolism
CBI37_RS01950	COG0799	negative regulation of ribosome biogenesis
CBI37_RS01955	COG2226	methyltransferase
CBI37_RS01960	COG1323	Belongs to the UPF0348 family
CBI37_RS01970	COG0333	Belongs to the bacterial ribosomal protein bL32 family
CBI37_RS01985	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
CBI37_RS01990	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CBI37_RS01995	COG0745	RESPONSE REGULATOR receiver
CBI37_RS02000	COG5002	protein histidine kinase activity
CBI37_RS02010	COG0419	ATPase involved in DNA repair
CBI37_RS02025	COG0706	membrane insertase activity
CBI37_RS02030	COG1254	Belongs to the acylphosphatase family
CBI37_RS02035	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CBI37_RS02045	COG1733	regulation of RNA biosynthetic process
CBI37_RS02050	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
CBI37_RS02055	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CBI37_RS02055	COG0072	phenylalanine-tRNA ligase activity
CBI37_RS02060	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CBI37_RS02065	COG0572	uridine kinase
CBI37_RS02070	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CBI37_RS02095	COG4841	protein insertion into membrane
CBI37_RS02105	COG0768	penicillin binding
CBI37_RS02110	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CBI37_RS02115	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
CBI37_RS02120	COG0457	Tetratricopeptide repeat
CBI37_RS02120	COG0705	Rhomboid family
CBI37_RS02130	COG1940	carbohydrate kinase activity
CBI37_RS02150	COG0584	glycerophosphoryl diester phosphodiesterase
CBI37_RS02155	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
CBI37_RS02160	COG0789	Transcriptional regulator
CBI37_RS02210	COG0261	This protein binds to 23S rRNA in the presence of protein L20
CBI37_RS02220	COG0211	Belongs to the bacterial ribosomal protein bL27 family
CBI37_RS02225	COG0006	proline dipeptidase activity
CBI37_RS02230	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
CBI37_RS02235	COG1302	Protein conserved in bacteria
CBI37_RS02240	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CBI37_RS02245	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
CBI37_RS02250	COG1570	exodeoxyribonuclease VII activity
CBI37_RS02255	COG1722	exodeoxyribonuclease VII activity
CBI37_RS02260	COG0142	geranyltranstransferase activity
CBI37_RS02265	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
CBI37_RS02270	COG1438	arginine binding
CBI37_RS02275	COG0497	DNA recombination
CBI37_RS02290	COG1732	Glycine betaine
CBI37_RS02305	COG0194	GDP metabolic process
CBI37_RS02310	COG1758	RNA polymerase activity
CBI37_RS02315	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CBI37_RS02320	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CBI37_RS02325	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CBI37_RS02330	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CBI37_RS02330	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CBI37_RS02335	COG0631	protein serine/threonine phosphatase activity
CBI37_RS02340	COG2815	serine threonine protein kinase
CBI37_RS02340	COG0515	serine threonine protein kinase
CBI37_RS02345	COG1162	GTPase activity
CBI37_RS02350	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CBI37_RS02355	COG1564	THIamine pyrophosphokinase
CBI37_RS02360	COG0227	Belongs to the bacterial ribosomal protein bL28 family
CBI37_RS02365	COG1302	Protein conserved in bacteria
CBI37_RS02370	COG1461	Dihydroxyacetone kinase
CBI37_RS02375	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CBI37_RS02380	COG0416	fatty acid biosynthetic process
CBI37_RS02385	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CBI37_RS02390	COG0571	ribonuclease III activity
CBI37_RS02395	COG1196	nuclear chromosome segregation
CBI37_RS02400	COG0552	protein localization to endoplasmic reticulum
CBI37_RS02405	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
CBI37_RS02410	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CBI37_RS02415	COG0228	four-way junction DNA binding
CBI37_RS02420	COG1837	Belongs to the UPF0109 family
CBI37_RS02425	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
CBI37_RS02430	COG0336	Belongs to the RNA methyltransferase TrmD family
CBI37_RS02435	COG0335	large ribosomal subunit rRNA binding
CBI37_RS02455	COG1131	(ABC) transporter
CBI37_RS02470	COG0512	Glutamine amidotransferase of anthranilate synthase
CBI37_RS02470	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CBI37_RS02475	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CBI37_RS02480	COG0134	indole-3-glycerol-phosphate synthase activity
CBI37_RS02485	COG0135	phosphoribosylanthranilate isomerase activity
CBI37_RS02490	COG0133	tryptophan synthase activity
CBI37_RS02495	COG0159	tryptophan synthase activity
CBI37_RS02510	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CBI37_RS02520	COG1473	amidohydrolase
CBI37_RS02525	COG1063	alcohol dehydrogenase
CBI37_RS02535	COG0300	oxidoreductase activity
CBI37_RS02545	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CBI37_RS02550	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CBI37_RS02555	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CBI37_RS02560	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
CBI37_RS02565	COG1028	Short-chain dehydrogenase reductase Sdr
CBI37_RS02570	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CBI37_RS02585	COG0439	Biotin carboxylase
CBI37_RS02600	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
CBI37_RS02610	COG1811	Na channel or pump
CBI37_RS02615	COG0583	DNA-binding transcription factor activity
CBI37_RS02620	COG1607	acyl-coa hydrolase
CBI37_RS02625	COG1162	GTPase activity
CBI37_RS02635	COG0477	Major facilitator Superfamily
CBI37_RS02680	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CBI37_RS02685	COG3397	chitin binding
CBI37_RS02700	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
CBI37_RS02710	COG3152	Membrane
CBI37_RS02715	COG1597	lipid kinase activity
CBI37_RS02730	COG2261	transglycosylase associated protein
CBI37_RS02735	COG3237	CsbD-like
CBI37_RS02750	COG1942	4-Oxalocrotonate Tautomerase
CBI37_RS02790	COG0531	amino acid
CBI37_RS02795	COG0561	phosphatase activity
CBI37_RS02800	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CBI37_RS02800	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
CBI37_RS02820	COG2017	converts alpha-aldose to the beta-anomer
CBI37_RS02825	COG1304	FMN binding
CBI37_RS02850	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CBI37_RS02850	COG1199	ATP-dependent helicase activity
CBI37_RS02865	COG0017	Asparaginyl-tRNA synthetase
CBI37_RS02880	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CBI37_RS02885	COG2011	ABC-type metal ion transport system permease component
CBI37_RS02890	COG1464	Belongs to the NlpA lipoprotein family
CBI37_RS02900	COG1177	transmembrane transport
CBI37_RS02905	COG1840	ABC-type Fe3 transport system, periplasmic component
CBI37_RS02920	COG3331	DNA recombination
CBI37_RS02925	COG4474	Belongs to the UPF0398 family
CBI37_RS02930	COG3599	regulation of cell shape
CBI37_RS02940	COG0116	Belongs to the methyltransferase superfamily
CBI37_RS02945	COG1073	alpha beta
CBI37_RS02955	COG1216	Glycosyl transferase, family 2
CBI37_RS02975	COG1619	proteins homologs of microcin C7 resistance protein MccF
CBI37_RS03000	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CBI37_RS03015	COG2759	Belongs to the formate--tetrahydrofolate ligase family
CBI37_RS03020	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
CBI37_RS03025	COG0564	pseudouridine synthase activity
CBI37_RS03030	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
CBI37_RS03035	COG0505	Belongs to the CarA family
CBI37_RS03040	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
CBI37_RS03055	COG5646	InterPro IPR014922
CBI37_RS03080	COG1131	(ABC) transporter
CBI37_RS03090	COG1293	RNA-binding protein homologous to eukaryotic snRNP
CBI37_RS03100	COG1307	EDD domain protein, DegV family
CBI37_RS03160	COG1113	amino acid transport
CBI37_RS03180	COG1620	l-lactate permease
CBI37_RS03190	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
CBI37_RS03215	COG1846	Transcriptional regulator
CBI37_RS03220	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CBI37_RS03255	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CBI37_RS03260	COG1227	inorganic diphosphatase activity
CBI37_RS03265	COG0583	DNA-binding transcription factor activity
CBI37_RS03275	COG0187	DNA topoisomerase II activity
CBI37_RS03280	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
CBI37_RS03290	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
CBI37_RS03295	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
CBI37_RS03300	COG4974	Belongs to the 'phage' integrase family
CBI37_RS03305	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
CBI37_RS03310	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CBI37_RS03315	COG0758	DNA mediated transformation
CBI37_RS03320	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CBI37_RS03325	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
CBI37_RS03335	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
CBI37_RS03340	COG0583	DNA-binding transcription factor activity
CBI37_RS03355	COG2814	Major facilitator Superfamily
CBI37_RS03365	COG3409	Peptidoglycan-binding domain 1 protein
CBI37_RS03365	COG0793	Belongs to the peptidase S41A family
CBI37_RS03370	COG4479	Belongs to the UPF0346 family
CBI37_RS03375	COG4698	Protein conserved in bacteria
CBI37_RS03380	COG2755	lipolytic protein G-D-S-L family
CBI37_RS03385	COG1307	EDD domain protein, DegV family
CBI37_RS03390	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
CBI37_RS03395	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
CBI37_RS03400	COG0488	(ABC) transporter
CBI37_RS03410	COG0617	tRNA 3'-terminal CCA addition
CBI37_RS03415	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
CBI37_RS03420	COG0561	phosphatase activity
CBI37_RS03425	COG0457	Tetratricopeptide repeat
CBI37_RS03440	COG1160	GTP binding
CBI37_RS03445	COG0539	negative regulation of cytoplasmic translation
CBI37_RS03450	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
CBI37_RS03460	COG0514	ATP-dependent DNA helicase (RecQ)
CBI37_RS03470	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
CBI37_RS03475	COG1187	pseudouridine synthase activity
CBI37_RS03480	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
CBI37_RS03485	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
CBI37_RS03495	COG4974	Belongs to the 'phage' integrase family
CBI37_RS03500	COG2996	Protein conserved in bacteria
CBI37_RS03520	COG0205	6-phosphofructokinase activity
CBI37_RS03525	COG0587	DNA-directed DNA polymerase activity
CBI37_RS03535	COG0542	response to heat
CBI37_RS03545	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
CBI37_RS03550	COG2384	SAM-dependent methyltransferase
CBI37_RS03575	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CBI37_RS03575	COG0574	Belongs to the PEP-utilizing enzyme family
CBI37_RS03585	COG1846	Transcriptional regulator
CBI37_RS03605	COG2217	Heavy metal translocating P-type atpase
CBI37_RS03610	COG0148	phosphopyruvate hydratase activity
CBI37_RS03615	COG0477	Major facilitator Superfamily
CBI37_RS03625	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CBI37_RS03630	COG0446	pyridine nucleotide-disulphide oxidoreductase
CBI37_RS03635	COG1349	DNA-binding transcription factor activity
CBI37_RS03645	COG1393	Belongs to the ArsC family
CBI37_RS03665	COG0546	phosphoglycolate phosphatase activity
CBI37_RS03695	COG0583	DNA-binding transcription factor activity
CBI37_RS03700	COG0604	alcohol dehydrogenase
CBI37_RS03710	COG0446	pyridine nucleotide-disulphide oxidoreductase
CBI37_RS03715	COG2197	response regulator
CBI37_RS03720	COG4585	Histidine kinase
CBI37_RS03730	COG1131	(ABC) transporter
CBI37_RS03740	COG0519	Catalyzes the synthesis of GMP from XMP
CBI37_RS03755	COG1131	(ABC) transporter
CBI37_RS03775	COG1131	(ABC) transporter
CBI37_RS03780	COG1725	Transcriptional regulator
CBI37_RS03790	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CBI37_RS03795	COG0358	DNA primase activity
CBI37_RS03800	COG0751	glycine-tRNA ligase activity
CBI37_RS03805	COG0752	glycyl-tRNA synthetase alpha subunit
CBI37_RS03810	COG1381	Involved in DNA repair and RecF pathway recombination
CBI37_RS03815	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
CBI37_RS03820	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
CBI37_RS03825	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
CBI37_RS03830	COG1702	phosphate starvation-inducible protein PhoH
CBI37_RS03835	COG1610	YqeY-like protein
CBI37_RS03840	COG0828	Belongs to the bacterial ribosomal protein bS21 family
CBI37_RS03845	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
CBI37_RS03855	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
CBI37_RS03865	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CBI37_RS03875	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
CBI37_RS03880	COG0124	histidyl-tRNA synthetase
CBI37_RS03885	COG0860	N-Acetylmuramoyl-L-alanine amidase
CBI37_RS03885	COG3103	Sh3 type 3 domain protein
CBI37_RS03885	COG4991	sh3 domain protein
CBI37_RS03890	COG3001	Fructosamine kinase
CBI37_RS03895	COG0546	phosphoglycolate phosphatase activity
CBI37_RS03900	COG1490	D-aminoacyl-tRNA deacylase activity
CBI37_RS03905	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CBI37_RS03915	COG1385	rRNA (uridine-N3-)-methyltransferase activity
CBI37_RS03920	COG2264	protein methyltransferase activity
CBI37_RS03925	COG2094	Belongs to the DNA glycosylase MPG family
CBI37_RS03940	COG0481	GTPase activity
CBI37_RS03945	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
CBI37_RS03950	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CBI37_RS03955	COG1696	Membrane protein involved in D-alanine export
CBI37_RS03960	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CBI37_RS03970	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CBI37_RS03975	COG0484	heat shock protein binding
CBI37_RS03980	COG0443	Heat shock 70 kDa protein
CBI37_RS03985	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
CBI37_RS03990	COG1420	regulation of RNA biosynthetic process
CBI37_RS03995	COG3527	Alpha-acetolactate decarboxylase
CBI37_RS04000	COG0196	riboflavin kinase activity
CBI37_RS04005	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
CBI37_RS04010	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
CBI37_RS04015	COG0287	Prephenate dehydrogenase
CBI37_RS04020	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
CBI37_RS04030	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
CBI37_RS04035	COG0738	Major facilitator superfamily
CBI37_RS04040	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
CBI37_RS04045	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
CBI37_RS04055	COG2740	Nucleic-acid-binding protein implicated in transcription termination
CBI37_RS04060	COG0195	Participates in both transcription termination and antitermination
CBI37_RS04065	COG0779	Required for maturation of 30S ribosomal subunits
CBI37_RS04070	COG2176	DNA-directed DNA polymerase activity
CBI37_RS04075	COG0442	prolyl-tRNA aminoacylation
CBI37_RS04080	COG0750	zinc metalloprotease
CBI37_RS04085	COG4589	Belongs to the CDS family
CBI37_RS04090	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CBI37_RS04095	COG0233	cytoplasmic translational termination
CBI37_RS04100	COG0528	UMP kinase activity
CBI37_RS04105	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
CBI37_RS04110	COG0052	Belongs to the universal ribosomal protein uS2 family
CBI37_RS04120	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CBI37_RS04125	COG2827	Endonuclease containing a URI domain
CBI37_RS04130	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
CBI37_RS04135	COG0204	Acyl-transferase
CBI37_RS04140	COG3763	UPF0154 protein
CBI37_RS04145	COG4224	UPF0291 protein
CBI37_RS04150	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CBI37_RS04165	COG3425	synthase
CBI37_RS04180	COG0463	Glycosyl transferase, family 2
CBI37_RS04195	COG1116	anion transmembrane transporter activity
CBI37_RS04205	COG0772	Belongs to the SEDS family
CBI37_RS04240	COG0393	Putative heavy-metal-binding
CBI37_RS04255	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CBI37_RS04260	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
CBI37_RS04260	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
CBI37_RS04265	COG5416	Lipopolysaccharide assembly protein A domain
CBI37_RS04270	COG0300	oxidoreductase activity
CBI37_RS04275	COG1234	tRNA 3'-trailer cleavage
CBI37_RS04285	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
CBI37_RS04290	COG1349	DNA-binding transcription factor activity
CBI37_RS04295	COG1105	Belongs to the carbohydrate kinase PfkB family
CBI37_RS04300	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CBI37_RS04300	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CBI37_RS04300	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CBI37_RS04330	COG0438	transferase activity, transferring glycosyl groups
CBI37_RS04335	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CBI37_RS04340	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CBI37_RS04350	COG0489	protein tyrosine kinase activity
CBI37_RS04360	COG0322	excinuclease ABC activity
CBI37_RS04365	COG1126	abc transporter atp-binding protein
CBI37_RS04370	COG0765	amino acid transport
CBI37_RS04390	COG0218	Necessary for normal cell division and for the maintenance of normal septation
CBI37_RS04395	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
CBI37_RS04400	COG0544	peptidyl-prolyl cis-trans isomerase activity
CBI37_RS04405	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CBI37_RS04430	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
CBI37_RS04435	COG0268	Binds directly to 16S ribosomal RNA
CBI37_RS04440	COG1466	dna polymerase III delta subunit
CBI37_RS04445	COG2333	competence protein COMEC
CBI37_RS04445	COG0658	competence protein
CBI37_RS04450	COG2131	deaminase
CBI37_RS04455	COG1596	polysaccharide export
CBI37_RS04455	COG1555	photosystem II stabilization
CBI37_RS04460	COG3480	Lon protease (S16) C-terminal proteolytic domain
CBI37_RS04465	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
CBI37_RS04470	COG0742	ribosomal rna small subunit methyltransferase
CBI37_RS04475	COG4471	UPF0298 protein
CBI37_RS04480	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
CBI37_RS04485	COG0772	Belongs to the SEDS family
CBI37_RS04520	COG1217	gtp-binding protein TYPA
CBI37_RS04525	COG0483	inositol monophosphate 1-phosphatase activity
CBI37_RS04530	COG4476	Belongs to the UPF0223 family
CBI37_RS04535	COG0039	L-malate dehydrogenase activity
CBI37_RS04560	COG0242	peptide deformylase activity
CBI37_RS04570	COG5503	Protein of unknown function (DUF1447)
CBI37_RS04575	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
CBI37_RS04580	COG1597	lipid kinase activity
CBI37_RS04590	COG1388	LysM domain
CBI37_RS04590	COG3584	3D domain protein
CBI37_RS04595	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CBI37_RS04600	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CBI37_RS04635	COG0569	domain protein
CBI37_RS04640	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CBI37_RS04645	COG0482	sulfurtransferase activity
CBI37_RS04655	COG1104	cysteine desulfurase activity
CBI37_RS04660	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CBI37_RS04670	COG0494	nUDIX hydrolase
CBI37_RS04675	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
CBI37_RS04685	COG3279	Response regulator of the LytR AlgR family
CBI37_RS04700	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
CBI37_RS04705	COG3599	regulation of cell shape
CBI37_RS04715	COG0762	integral membrane protein
CBI37_RS04720	COG1799	cell septum assembly
CBI37_RS04735	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
CBI37_RS04740	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CBI37_RS04745	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
CBI37_RS04750	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CBI37_RS04755	COG0768	penicillin binding
CBI37_RS04765	COG0275	rRNA processing
CBI37_RS04770	COG2001	Belongs to the MraZ family
CBI37_RS04790	COG1674	ftsk spoiiie
CBI37_RS04795	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
CBI37_RS04805	COG1114	Component of the transport system for branched-chain amino acids
CBI37_RS04820	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
CBI37_RS04825	COG0628	permease
CBI37_RS04835	COG2706	6-phosphogluconolactonase activity
CBI37_RS04840	COG3142	Participates in the control of copper homeostasis
CBI37_RS04845	COG0564	pseudouridine synthase activity
CBI37_RS04850	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CBI37_RS04855	COG2357	RelA SpoT domain protein
CBI37_RS04865	COG1164	Oligoendopeptidase f
CBI37_RS04875	COG4862	establishment of competence for transformation
CBI37_RS04880	COG1393	Belongs to the ArsC family
CBI37_RS04885	COG1234	tRNA 3'-trailer cleavage
CBI37_RS05030	COG1098	S1 RNA binding domain
CBI37_RS05040	COG0586	Pfam SNARE associated Golgi protein
CBI37_RS05050	COG0647	UMP catabolic process
CBI37_RS05055	COG4470	Protein conserved in bacteria
CBI37_RS05060	COG0737	Belongs to the 5'-nucleotidase family
CBI37_RS05075	COG1113	amino acid transport
CBI37_RS05080	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CBI37_RS05085	COG0827	DNA restriction-modification system
CBI37_RS05115	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CBI37_RS05125	COG0217	transcriptional regulatory protein
CBI37_RS05140	COG1609	Transcriptional regulator
CBI37_RS05145	COG0006	proline dipeptidase activity
CBI37_RS05150	COG0789	Transcriptional regulator
CBI37_RS05165	COG0668	transmembrane transport
CBI37_RS05170	COG1473	amidohydrolase
CBI37_RS05175	COG2171	N-acyltransferase activity
CBI37_RS05180	COG0517	IMP dehydrogenase activity
CBI37_RS05190	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
CBI37_RS05195	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
CBI37_RS05200	COG1719	4-vinyl reductase, 4VR
CBI37_RS05205	COG3118	belongs to the thioredoxin family
CBI37_RS05210	COG1193	negative regulation of DNA recombination
CBI37_RS05220	COG3906	Belongs to the UPF0473 family
CBI37_RS05225	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
CBI37_RS05230	COG4472	Bacterial protein of unknown function (DUF965)
CBI37_RS05235	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CBI37_RS05240	COG0513	Belongs to the DEAD box helicase family
CBI37_RS05245	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
CBI37_RS05250	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CBI37_RS05255	COG1862	Preprotein translocase
CBI37_RS05260	COG0343	queuine tRNA-ribosyltransferase activity
CBI37_RS05265	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
CBI37_RS05270	COG2255	four-way junction helicase activity
CBI37_RS05275	COG0632	four-way junction helicase activity
CBI37_RS05305	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
CBI37_RS05310	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
CBI37_RS05315	COG1692	metallophosphoesterase
CBI37_RS05320	COG1418	mRNA catabolic process
CBI37_RS05325	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
CBI37_RS05330	COG1546	Belongs to the CinA family
CBI37_RS05330	COG1058	Belongs to the CinA family
CBI37_RS05335	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CBI37_RS05340	COG1426	Protein conserved in bacteria
CBI37_RS05345	COG0612	Peptidase, M16
CBI37_RS05350	COG0612	Peptidase, M16
CBI37_RS05355	COG0527	aspartate kinase activity
CBI37_RS05365	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CBI37_RS05370	COG1126	abc transporter atp-binding protein
CBI37_RS05375	COG0765	amino acid transport
CBI37_RS05380	COG2894	cell division
CBI37_RS05385	COG0850	regulation of cytokinetic process
CBI37_RS05395	COG1792	Involved in formation and maintenance of cell shape
CBI37_RS05400	COG1077	Cell shape determining protein MreB Mrl
CBI37_RS05405	COG2003	Belongs to the UPF0758 family
CBI37_RS05410	COG0285	dihydrofolate synthase activity
CBI37_RS05415	COG0525	valine-tRNA ligase activity
CBI37_RS05425	COG2918	glutathione biosynthetic process
CBI37_RS05425	COG1181	Belongs to the D-alanine--D-alanine ligase family
CBI37_RS05435	COG0301	tRNA thio-modification
CBI37_RS05440	COG1104	cysteine desulfurase activity
CBI37_RS05450	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
CBI37_RS05455	COG1956	GAF domain-containing protein
CBI37_RS05460	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
CBI37_RS05465	COG4493	Belongs to the UPF0637 family
CBI37_RS05480	COG0640	Transcriptional regulator
CBI37_RS05485	COG0366	Alpha amylase catalytic
CBI37_RS05495	COG3716	PTS system mannose fructose sorbose family IID component
CBI37_RS05500	COG3715	PTS system
CBI37_RS05505	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CBI37_RS05510	COG1609	Transcriptional regulator
CBI37_RS05515	COG2918	glutathione biosynthetic process
CBI37_RS05515	COG0189	ligase activity
CBI37_RS05520	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CBI37_RS05535	COG0589	response to stress
CBI37_RS05555	COG1181	Belongs to the D-alanine--D-alanine ligase family
CBI37_RS05575	COG1464	Belongs to the NlpA lipoprotein family
CBI37_RS05580	COG2011	ABC-type metal ion transport system permease component
CBI37_RS05585	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CBI37_RS05590	COG0509	glycine decarboxylation via glycine cleavage system
CBI37_RS05595	COG0772	Belongs to the SEDS family
CBI37_RS05605	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
CBI37_RS05610	COG1077	Cell shape determining protein MreB Mrl
CBI37_RS05620	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CBI37_RS05625	COG0355	proton-transporting ATP synthase activity, rotational mechanism
CBI37_RS05630	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
CBI37_RS05635	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
CBI37_RS05640	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
CBI37_RS05645	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CBI37_RS05650	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
CBI37_RS05655	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CBI37_RS05660	COG0356	it plays a direct role in the translocation of protons across the membrane
CBI37_RS05665	COG2233	PERMEase
CBI37_RS05675	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
CBI37_RS05680	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
CBI37_RS05685	COG0009	L-threonylcarbamoyladenylate synthase
CBI37_RS05690	COG2890	protein-(glutamine-N5) methyltransferase activity
CBI37_RS05695	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
CBI37_RS05700	COG1435	thymidine kinase activity
CBI37_RS05705	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
CBI37_RS05710	COG3442	glutamine amidotransferase
CBI37_RS05715	COG1482	cell wall glycoprotein biosynthetic process
CBI37_RS05720	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CBI37_RS05730	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CBI37_RS05750	COG1132	(ABC) transporter
CBI37_RS05765	COG0726	polysaccharide deacetylase
CBI37_RS05950	COG0629	single-stranded DNA binding
CBI37_RS06010	COG0513	Belongs to the DEAD box helicase family
CBI37_RS06015	COG0673	inositol 2-dehydrogenase activity
CBI37_RS06020	COG1278	Cold shock
CBI37_RS06035	COG1737	Transcriptional regulator
CBI37_RS06045	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CBI37_RS06060	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CBI37_RS06065	COG1597	lipid kinase activity
CBI37_RS06070	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CBI37_RS06075	COG0154	amidase activity
CBI37_RS06080	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CBI37_RS06085	COG4851	CamS sex pheromone cAM373 precursor
CBI37_RS06090	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CBI37_RS06100	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
CBI37_RS06105	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
CBI37_RS06110	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CBI37_RS06115	COG1705	Flagellar rod assembly protein muramidase FlgJ
CBI37_RS06130	COG0142	geranyltranstransferase activity
CBI37_RS06145	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
CBI37_RS06150	COG4988	ABC transporter
CBI37_RS06155	COG1294	oxidase, subunit
CBI37_RS06160	COG1271	oxidase subunit
CBI37_RS06175	COG4684	Psort location CytoplasmicMembrane, score
CBI37_RS06180	COG0531	amino acid
CBI37_RS06190	COG0281	malic enzyme
CBI37_RS06195	COG0583	DNA-binding transcription factor activity
CBI37_RS06205	COG0583	DNA-binding transcription factor activity
CBI37_RS06215	COG1053	succinate dehydrogenase
CBI37_RS06220	COG0114	fumarate hydratase activity
CBI37_RS06240	COG3052	prosthetic group binding
CBI37_RS06260	COG0471	metal ion transport
CBI37_RS06265	COG0039	L-malate dehydrogenase activity
CBI37_RS06275	COG0803	Belongs to the bacterial solute-binding protein 9 family
CBI37_RS06280	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CBI37_RS06285	COG1121	(ABC) transporter
CBI37_RS06290	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
CBI37_RS06295	COG1917	Cupin 2, conserved barrel domain protein
CBI37_RS06295	COG4977	sequence-specific DNA binding
CBI37_RS06305	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
CBI37_RS06310	COG2151	metal-sulfur cluster biosynthetic enzyme
CBI37_RS06315	COG0471	metal ion transport
CBI37_RS06320	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
CBI37_RS06325	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
CBI37_RS06330	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CBI37_RS06335	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CBI37_RS06355	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
CBI37_RS06475	COG1783	phage Terminase large subunit
CBI37_RS06480	COG5484	DNA packaging
CBI37_RS06540	COG0270	DNA (cytosine-5-)-methyltransferase activity
CBI37_RS06640	COG4974	Belongs to the 'phage' integrase family
CBI37_RS06645	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
CBI37_RS06650	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
CBI37_RS06655	COG0101	tRNA pseudouridine synthase activity
CBI37_RS06665	COG1122	ATPase activity
CBI37_RS06670	COG1122	ATPase activity
CBI37_RS06680	COG4939	FMN-binding domain protein
CBI37_RS06705	COG0203	ribosomal protein L17
CBI37_RS06710	COG0202	RNA polymerase activity
CBI37_RS06715	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
CBI37_RS06720	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
CBI37_RS06725	COG0257	Belongs to the bacterial ribosomal protein bL36 family
CBI37_RS06730	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
CBI37_RS06735	COG0563	adenylate kinase activity
CBI37_RS06745	COG0200	Binds to the 23S rRNA
CBI37_RS06750	COG1841	ribosomal large subunit assembly
CBI37_RS06755	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
CBI37_RS06760	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
CBI37_RS06765	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
CBI37_RS06770	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
CBI37_RS06775	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
CBI37_RS06780	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
CBI37_RS06785	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
CBI37_RS06790	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
CBI37_RS06795	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
CBI37_RS06800	COG0255	Belongs to the universal ribosomal protein uL29 family
CBI37_RS06805	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
CBI37_RS06810	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
CBI37_RS06815	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
CBI37_RS06820	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
CBI37_RS06825	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
CBI37_RS06830	COG0089	rRNA binding
CBI37_RS06835	COG0088	Forms part of the polypeptide exit tunnel
CBI37_RS06840	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
CBI37_RS06845	COG0051	transcription antitermination factor activity, RNA binding
CBI37_RS06850	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CBI37_RS06855	COG0049	tRNA binding
CBI37_RS06860	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
CBI37_RS06865	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
CBI37_RS06870	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CBI37_RS06875	COG0085	RNA polymerase activity
CBI37_RS06885	COG0542	response to heat
CBI37_RS06890	COG4463	regulation of RNA biosynthetic process
CBI37_RS06930	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
CBI37_RS06935	COG1428	Deoxynucleoside kinase
CBI37_RS06945	COG0833	amino acid
CBI37_RS06950	COG0028	Belongs to the TPP enzyme family
CBI37_RS06955	COG1959	2 iron, 2 sulfur cluster binding
CBI37_RS06975	COG1316	TRANSCRIPTIONal
CBI37_RS06985	COG2966	Psort location CytoplasmicMembrane, score
CBI37_RS06990	COG1278	Cold shock
CBI37_RS07010	COG2814	Major facilitator Superfamily
CBI37_RS07060	COG0367	asparagine synthase
CBI37_RS07065	COG0527	aspartate kinase activity
CBI37_RS07070	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CBI37_RS07120	COG0640	Transcriptional regulator
CBI37_RS07125	COG0564	pseudouridine synthase activity
CBI37_RS07130	COG0514	ATP-dependent DNA helicase (RecQ)
CBI37_RS07150	COG4690	dipeptidase activity
CBI37_RS07155	COG2502	aspartate--ammonia ligase
CBI37_RS07160	COG0017	Asparaginyl-tRNA synthetase
CBI37_RS07165	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
CBI37_RS07175	COG1053	succinate dehydrogenase
CBI37_RS07180	COG0583	DNA-binding transcription factor activity
CBI37_RS07195	COG0572	uridine kinase
CBI37_RS07225	COG0308	aminopeptidase N
CBI37_RS07255	COG1302	Protein conserved in bacteria
CBI37_RS07270	COG2261	transglycosylase associated protein
CBI37_RS07275	COG2755	lipolytic protein G-D-S-L family
CBI37_RS07275	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
CBI37_RS07290	COG2814	Major facilitator Superfamily
CBI37_RS07295	COG1733	regulation of RNA biosynthetic process
CBI37_RS07300	COG1266	CAAX protease self-immunity
CBI37_RS07305	COG1396	sequence-specific DNA binding
CBI37_RS07350	COG0464	growth
CBI37_RS07355	COG0519	Catalyzes the synthesis of GMP from XMP
CBI37_RS07355	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CBI37_RS07360	COG1072	(Pantothenic acid kinase))
CBI37_RS07365	COG2070	2-Nitropropane dioxygenase
CBI37_RS07370	COG3973	AAA domain
CBI37_RS07375	COG0586	Pfam SNARE associated Golgi protein
CBI37_RS07380	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
CBI37_RS07380	COG0456	acetyltransferase
CBI37_RS07385	COG0569	domain protein
CBI37_RS07385	COG0475	glutathione-regulated potassium exporter activity
CBI37_RS07390	COG0588	phosphoglycerate mutase activity
CBI37_RS07405	COG2076	Multidrug Resistance protein
CBI37_RS07415	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CBI37_RS07445	COG1846	Transcriptional regulator
CBI37_RS07455	COG0531	amino acid
CBI37_RS07460	COG3394	polysaccharide catabolic process
CBI37_RS07465	COG1263	PTS System
CBI37_RS07465	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CBI37_RS07475	COG1263	PTS System
CBI37_RS07475	COG2190	(PTS) system
CBI37_RS07475	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CBI37_RS07480	COG0765	amino acid transport
CBI37_RS07485	COG0765	amino acid transport
CBI37_RS07490	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CBI37_RS07510	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CBI37_RS07515	COG0436	Aminotransferase
CBI37_RS07520	COG0546	phosphoglycolate phosphatase activity
CBI37_RS07535	COG0735	belongs to the Fur family
CBI37_RS07540	COG0194	GDP metabolic process
CBI37_RS07565	COG0531	amino acid
CBI37_RS07580	COG2936	dipeptidyl-peptidase activity
CBI37_RS07585	COG2755	lipolytic protein G-D-S-L family
CBI37_RS07585	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
CBI37_RS07595	COG2267	carboxylic ester hydrolase activity
CBI37_RS07600	COG0028	Belongs to the TPP enzyme family
CBI37_RS07605	COG0196	riboflavin kinase activity
CBI37_RS07610	COG0028	Belongs to the TPP enzyme family
CBI37_RS07615	COG2252	PERMEase
CBI37_RS07630	COG3475	LICD family
CBI37_RS07640	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
CBI37_RS07645	COG0248	Ppx GppA phosphatase
CBI37_RS07650	COG0477	Major facilitator Superfamily
CBI37_RS07665	COG1393	Belongs to the ArsC family
CBI37_RS07680	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CBI37_RS07705	COG0778	Nitroreductase
CBI37_RS07720	COG2017	converts alpha-aldose to the beta-anomer
CBI37_RS07730	COG0561	phosphatase activity
CBI37_RS07740	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CBI37_RS07745	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CBI37_RS07770	COG0025	NhaP-type Na H and K H
CBI37_RS07775	COG0812	UDP-N-acetylmuramate dehydrogenase activity
CBI37_RS07785	COG0708	Exodeoxyribonuclease III
CBI37_RS07800	COG0802	atpase or kinase
CBI37_RS07805	COG0280	phosphate acetyltransferase
CBI37_RS07810	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
CBI37_RS07815	COG0561	phosphatase activity
CBI37_RS07825	COG1126	abc transporter atp-binding protein
CBI37_RS07830	COG0765	amino acid transport
CBI37_RS07840	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
CBI37_RS07845	COG0557	exoribonuclease II activity
CBI37_RS07855	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CBI37_RS07860	COG0038	chloride channel
CBI37_RS07875	COG0148	phosphopyruvate hydratase activity
CBI37_RS07880	COG0149	triose-phosphate isomerase activity
CBI37_RS07885	COG0126	phosphoglycerate kinase activity
CBI37_RS07895	COG2390	Transcriptional regulator
CBI37_RS07910	COG0740	serine-type endopeptidase activity
CBI37_RS07915	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CBI37_RS07925	COG1481	regulation of sporulation
CBI37_RS07935	COG1660	Displays ATPase and GTPase activities
CBI37_RS07945	COG0165	Argininosuccinate lyase
CBI37_RS07950	COG0137	argininosuccinate synthase activity
CBI37_RS07955	COG1854	S-ribosylhomocysteine lyase activity
CBI37_RS07960	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CBI37_RS07965	COG0556	nucleotide-excision repair
CBI37_RS07975	COG2814	Major facilitator Superfamily
CBI37_RS07985	COG0446	pyridine nucleotide-disulphide oxidoreductase
CBI37_RS07995	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CBI37_RS08005	COG2323	membrane
CBI37_RS08010	COG0492	ferredoxin-NADP+ reductase activity
CBI37_RS08025	COG1215	transferase activity, transferring glycosyl groups
CBI37_RS08045	COG0446	pyridine nucleotide-disulphide oxidoreductase
CBI37_RS08055	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CBI37_RS08060	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
CBI37_RS08065	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
CBI37_RS08070	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
CBI37_RS08075	COG1950	PFAM Membrane protein of
CBI37_RS08080	COG1983	PspC domain protein
CBI37_RS08085	COG0704	Plays a role in the regulation of phosphate uptake
CBI37_RS08090	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CBI37_RS08095	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CBI37_RS08100	COG0581	inorganic phosphate transmembrane transporter activity
CBI37_RS08105	COG0573	inorganic phosphate transmembrane transporter activity
CBI37_RS08110	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
CBI37_RS08115	COG5002	protein histidine kinase activity
CBI37_RS08120	COG0745	RESPONSE REGULATOR receiver
CBI37_RS08135	COG0653	protein targeting
CBI37_RS08150	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
CBI37_RS08155	COG1739	Uncharacterized protein family UPF0029
CBI37_RS08160	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
CBI37_RS08165	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CBI37_RS08170	COG0531	amino acid
CBI37_RS08175	COG0459	protein refolding
CBI37_RS08180	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
CBI37_RS08190	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
CBI37_RS08195	COG0488	(ABC) transporter
CBI37_RS08205	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
CBI37_RS08210	COG0456	acetyltransferase
CBI37_RS08215	COG0456	acetyltransferase
CBI37_RS08220	COG1214	PFAM Peptidase M22, glycoprotease
CBI37_RS08230	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
CBI37_RS08240	COG3639	organic phosphonate transmembrane transporter activity
CBI37_RS08245	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CBI37_RS08250	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
CBI37_RS08255	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CBI37_RS08270	COG4467	Involved in initiation control of chromosome replication
CBI37_RS08275	COG0470	DNA polymerase III
CBI37_RS08280	COG3870	Protein conserved in bacteria
CBI37_RS08285	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
CBI37_RS08295	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
CBI37_RS08300	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
CBI37_RS08305	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CBI37_RS08320	COG2813	Specifically methylates the guanine in position
CBI37_RS08325	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CBI37_RS08330	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CBI37_RS08340	COG1611	Belongs to the LOG family
CBI37_RS08360	COG0222	ribosome binding
CBI37_RS08365	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
CBI37_RS08370	COG0081	regulation of translation
CBI37_RS08375	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
CBI37_RS08385	COG0250	Participates in transcription elongation, termination and antitermination
CBI37_RS08395	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CBI37_RS08410	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CBI37_RS08415	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
CBI37_RS08420	COG0215	cysteine-tRNA ligase activity
CBI37_RS08425	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CBI37_RS08430	COG4956	integral membrane protein (PIN domain superfamily)
CBI37_RS08455	COG0756	dUTP diphosphatase activity
CBI37_RS08465	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
CBI37_RS08480	COG0588	phosphoglycerate mutase activity
CBI37_RS08485	COG0697	spore germination
CBI37_RS08495	COG1316	TRANSCRIPTIONal
CBI37_RS08500	COG0825	malonyl-CoA metabolic process
CBI37_RS08510	COG0439	Biotin carboxylase
CBI37_RS08520	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CBI37_RS08525	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
CBI37_RS08525	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CBI37_RS08530	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CBI37_RS08530	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
CBI37_RS08535	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
CBI37_RS08535	COG3933	PFAM sigma-54 factor interaction domain-containing protein
CBI37_RS08545	COG3716	PTS system mannose fructose sorbose family IID component
CBI37_RS08550	COG3715	PTS system
CBI37_RS08575	COG3409	Peptidoglycan-binding domain 1 protein
CBI37_RS08590	COG0083	homoserine kinase activity
CBI37_RS08595	COG0460	homoserine dehydrogenase
CBI37_RS08600	COG3091	SprT-like family
CBI37_RS08605	COG2183	response to ionizing radiation
CBI37_RS08620	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
CBI37_RS08625	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
CBI37_RS08635	COG2188	Transcriptional regulator
CBI37_RS08645	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CBI37_RS08695	COG3104	oligopeptide transport
CBI37_RS08735	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
CBI37_RS08740	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CBI37_RS08745	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
CBI37_RS08760	COG0037	tRNA processing
CBI37_RS08765	COG1098	S1 RNA binding domain
CBI37_RS08775	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
CBI37_RS08780	COG2244	polysaccharide biosynthetic process
CBI37_RS08785	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CBI37_RS08790	COG0193	aminoacyl-tRNA hydrolase activity
CBI37_RS08795	COG0039	L-malate dehydrogenase activity
CBI37_RS08810	COG2267	carboxylic ester hydrolase activity
CBI37_RS08825	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
CBI37_RS08830	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CBI37_RS08835	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
CBI37_RS08840	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
CBI37_RS08845	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
CBI37_RS08850	COG0505	Belongs to the CarA family
CBI37_RS08855	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
CBI37_RS08875	COG3158	transport of potassium into the cell
CBI37_RS08880	COG2337	Toxic component of a toxin-antitoxin (TA) module
CBI37_RS08885	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CBI37_RS08890	COG0736	holo-[acyl-carrier-protein] synthase activity
CBI37_RS08910	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
CBI37_RS08920	COG0501	Belongs to the peptidase M48B family
CBI37_RS08925	COG1704	LemA family
CBI37_RS08930	COG3764	Sortase (surface protein transpeptidase)
CBI37_RS08940	COG0254	rRNA binding
CBI37_RS08945	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
CBI37_RS08950	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CBI37_RS08965	COG1760	l-serine dehydratase
CBI37_RS08970	COG1760	l-serine dehydratase
CBI37_RS08980	COG0814	amino acid
CBI37_RS08985	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
CBI37_RS08990	COG0504	CTP synthase activity
CBI37_RS08995	COG3343	RNA polymerase activity
CBI37_RS09005	COG0095	Lipoate-protein ligase
CBI37_RS09010	COG1078	dGTPase activity
CBI37_RS09035	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CBI37_RS09045	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
CBI37_RS09050	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CBI37_RS09075	COG1321	iron dependent repressor
CBI37_RS09075	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CBI37_RS09080	COG1121	(ABC) transporter
CBI37_RS09085	COG1073	alpha beta
CBI37_RS09090	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
CBI37_RS09095	COG4466	Protein conserved in bacteria
CBI37_RS09100	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
CBI37_RS09105	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
CBI37_RS09110	COG0084	hydrolase, TatD family'
CBI37_RS09115	COG2814	Major facilitator Superfamily
CBI37_RS09120	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CBI37_RS09120	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CBI37_RS09130	COG1801	Protein of unknown function DUF72
CBI37_RS09135	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
CBI37_RS09150	COG0248	Ppx GppA phosphatase
CBI37_RS09165	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CBI37_RS09175	COG1940	carbohydrate kinase activity
CBI37_RS09180	COG2723	6-phospho-beta-galactosidase activity
CBI37_RS09185	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CBI37_RS09200	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CBI37_RS09205	COG2188	Transcriptional regulator
CBI37_RS09210	COG0180	Tryptophanyl-tRNA synthetase
CBI37_RS09215	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CBI37_RS09220	COG3973	AAA domain
CBI37_RS09255	COG2274	protein secretion by the type I secretion system
CBI37_RS09280	COG3279	Response regulator of the LytR AlgR family
CBI37_RS09305	COG0463	Glycosyl transferase, family 2
CBI37_RS09355	COG1114	Component of the transport system for branched-chain amino acids
CBI37_RS09360	COG0561	phosphatase activity
CBI37_RS09370	COG0561	phosphatase activity
CBI37_RS09380	COG0110	maltose O-acetyltransferase activity
CBI37_RS09445	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
CBI37_RS09455	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CBI37_RS09465	COG1125	glycine betaine transport
CBI37_RS09485	COG0300	oxidoreductase activity
CBI37_RS09515	COG1881	PFAM PEBP family protein
CBI37_RS09520	COG3759	membrane
CBI37_RS09530	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
CBI37_RS09550	COG0004	ammonium transporteR
CBI37_RS09555	COG2814	Major facilitator Superfamily
CBI37_RS09570	COG1134	teichoic acid transport
CBI37_RS09575	COG1682	transport, permease protein
CBI37_RS09585	COG0436	Aminotransferase
CBI37_RS09600	COG1268	BioY protein
CBI37_RS09640	COG1454	alcohol dehydrogenase
CBI37_RS09640	COG1012	belongs to the aldehyde dehydrogenase family
CBI37_RS09650	COG1131	(ABC) transporter
CBI37_RS09655	COG1725	Transcriptional regulator
CBI37_RS09685	COG3842	ATPase activity
CBI37_RS09725	COG1252	NADH dehydrogenase
CBI37_RS09730	COG1846	Transcriptional regulator
CBI37_RS09740	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CBI37_RS09770	COG1388	LysM domain
CBI37_RS09770	COG3942	CHAP domain
CBI37_RS09775	COG0741	lytic transglycosylase activity
CBI37_RS09790	COG1136	(ABC) transporter
CBI37_RS09795	COG0577	efflux transmembrane transporter activity
CBI37_RS09805	COG2818	Glycosylase
CBI37_RS09810	COG1033	growth of symbiont in host cell
CBI37_RS09810	COG2409	Drug exporters of the RND superfamily
CBI37_RS09820	COG2357	RelA SpoT domain protein
CBI37_RS09830	COG0277	FAD linked oxidase domain protein
CBI37_RS09835	COG1316	TRANSCRIPTIONal
CBI37_RS09850	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CBI37_RS09855	COG1737	Transcriptional regulator
CBI37_RS09865	COG0745	RESPONSE REGULATOR receiver
CBI37_RS09870	COG5002	protein histidine kinase activity
CBI37_RS09880	COG2814	Major facilitator Superfamily
CBI37_RS09905	COG1309	transcriptional regulator
CBI37_RS09910	COG1959	2 iron, 2 sulfur cluster binding
CBI37_RS09920	COG0163	prenyltransferase activity
CBI37_RS09930	COG1263	PTS System
CBI37_RS09930	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CBI37_RS09930	COG2190	(PTS) system
CBI37_RS09935	COG1263	PTS System
CBI37_RS09935	COG2190	(PTS) system
CBI37_RS09935	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CBI37_RS09940	COG0366	Alpha amylase catalytic
CBI37_RS09945	COG2188	Transcriptional regulator
CBI37_RS09975	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CBI37_RS09980	COG0626	cystathionine gamma-synthase activity
CBI37_RS09985	COG1045	serine acetyltransferase
CBI37_RS10005	COG3964	amidohydrolase
CBI37_RS10020	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CBI37_RS10025	COG2188	Transcriptional regulator
CBI37_RS10030	COG0431	NADPH-dependent FMN reductase
CBI37_RS10065	COG3118	belongs to the thioredoxin family
CBI37_RS10075	COG0246	Mannitol dehydrogenase
CBI37_RS10080	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
CBI37_RS10090	COG2213	PTS system mannitol-specific
CBI37_RS10100	COG0363	glucosamine-6-phosphate deaminase activity
CBI37_RS10115	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CBI37_RS10125	COG0386	Belongs to the glutathione peroxidase family
CBI37_RS10135	COG4172	Belongs to the ABC transporter superfamily
CBI37_RS10145	COG0488	(ABC) transporter
CBI37_RS10150	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CBI37_RS10155	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CBI37_RS10185	COG0667	Aldo Keto reductase
CBI37_RS10190	COG0406	alpha-ribazole phosphatase activity
CBI37_RS10195	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
CBI37_RS10200	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CBI37_RS10210	COG4166	transmembrane transport
CBI37_RS10240	COG1757	Na H antiporter
CBI37_RS10290	COG3842	ATPase activity
CBI37_RS10295	COG0366	Alpha amylase catalytic
CBI37_RS10305	COG3833	ABC-type maltose transport systems, permease component
CBI37_RS10310	COG1175	transmembrane transport
CBI37_RS10315	COG2182	Extracellular solute-binding protein
CBI37_RS10320	COG0366	Alpha amylase catalytic
CBI37_RS10325	COG1609	Transcriptional regulator
CBI37_RS10330	COG1609	Transcriptional regulator
CBI37_RS10335	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
CBI37_RS10340	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
CBI37_RS10345	COG1461	Dihydroxyacetone kinase
CBI37_RS10350	COG2376	Dihydroxyacetone kinase
CBI37_RS10355	COG2376	Dihydroxyacetone kinase
CBI37_RS10360	COG1309	transcriptional regulator
CBI37_RS10365	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
CBI37_RS10370	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
CBI37_RS10385	COG1131	(ABC) transporter
CBI37_RS10390	COG1028	Short-chain dehydrogenase reductase Sdr
CBI37_RS10415	COG2188	Transcriptional regulator
CBI37_RS10425	COG4720	Psort location CytoplasmicMembrane, score
CBI37_RS10430	COG1122	ATPase activity
CBI37_RS10435	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
CBI37_RS10465	COG0667	Aldo Keto reductase
CBI37_RS10470	COG0656	L-ascorbic acid biosynthetic process
CBI37_RS10475	COG2807	transmembrane transport
CBI37_RS10515	COG1983	PspC domain protein
CBI37_RS10525	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
CBI37_RS10530	COG2267	carboxylic ester hydrolase activity
CBI37_RS10540	COG1113	amino acid transport
CBI37_RS10555	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
CBI37_RS10565	COG0352	thiamine-phosphate diphosphorylase activity
CBI37_RS10570	COG0351	phosphomethylpyrimidine kinase
CBI37_RS10575	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
CBI37_RS10585	COG1606	tRNA processing
CBI37_RS10590	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
CBI37_RS10595	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
CBI37_RS10600	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
CBI37_RS10605	COG1691	(AIR) carboxylase
CBI37_RS10610	COG3875	lactate racemase activity
CBI37_RS10615	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CBI37_RS10620	COG0310	cobalt ion transport
CBI37_RS10625	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
CBI37_RS10630	COG1122	ATPase activity
CBI37_RS10655	COG4166	transmembrane transport
CBI37_RS10665	COG3022	response to hydroperoxide
CBI37_RS10670	COG2267	carboxylic ester hydrolase activity
CBI37_RS10695	COG0604	alcohol dehydrogenase
CBI37_RS10730	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
CBI37_RS10750	COG2368	4-hydroxyphenylacetate
CBI37_RS10755	COG2365	Tyrosine phosphatase family
CBI37_RS10765	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
CBI37_RS10770	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CBI37_RS10780	COG2508	Transcriptional regulator
CBI37_RS10785	COG0778	Nitroreductase
CBI37_RS10795	COG1028	Short-chain dehydrogenase reductase Sdr
CBI37_RS10800	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CBI37_RS10815	COG0471	metal ion transport
CBI37_RS10820	COG3976	FMN-binding domain protein
CBI37_RS10820	COG1053	succinate dehydrogenase
CBI37_RS10820	COG0431	NADPH-dependent FMN reductase
CBI37_RS10840	COG1573	uracil-dna glycosylase
CBI37_RS10845	COG1012	belongs to the aldehyde dehydrogenase family
CBI37_RS10855	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
CBI37_RS10860	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CBI37_RS10865	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
CBI37_RS10870	COG4853	Protein conserved in bacteria
CBI37_RS10880	COG5002	protein histidine kinase activity
CBI37_RS10885	COG0745	RESPONSE REGULATOR receiver
CBI37_RS10895	COG2226	methyltransferase
CBI37_RS10920	COG4695	Portal protein
CBI37_RS10990	COG1396	sequence-specific DNA binding
CBI37_RS11005	COG1278	Cold shock
CBI37_RS11015	COG1554	hydrolase, family 65, central catalytic
CBI37_RS11020	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CBI37_RS11030	COG0366	Alpha amylase catalytic
CBI37_RS11030	COG3103	Sh3 type 3 domain protein
CBI37_RS11035	COG0058	SHG alpha-glucan phosphorylase activity
CBI37_RS11040	COG0297	glycogen (starch) synthase activity
CBI37_RS11045	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
CBI37_RS11050	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
CBI37_RS11055	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
CBI37_RS11065	COG4166	transmembrane transport
CBI37_RS11070	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
CBI37_RS11075	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
CBI37_RS11080	COG2814	Major facilitator Superfamily
CBI37_RS11085	COG0305	Participates in initiation and elongation during chromosome replication
CBI37_RS11090	COG0359	binds to the 23S rRNA
CBI37_RS11100	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
CBI37_RS11105	COG0629	single-stranded DNA binding
CBI37_RS11110	COG0360	Binds together with S18 to 16S ribosomal RNA
CBI37_RS11120	COG0187	DNA topoisomerase II activity
CBI37_RS11125	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
CBI37_RS11130	COG2501	S4 domain
CBI37_RS11135	COG0592	DNA-directed DNA polymerase activity
CBI37_RS11140	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
CBI37_RS11145	COG0230	Belongs to the bacterial ribosomal protein bL34 family
CBI37_RS11150	COG0594	ribonuclease P activity
CBI37_RS11155	COG0706	membrane insertase activity
CBI37_RS11160	COG4166	transmembrane transport
CBI37_RS11170	COG1847	R3H domain protein
CBI37_RS11175	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
CBI37_RS11180	COG0445	tRNA wobble uridine modification
CBI37_RS11220	COG1307	EDD domain protein, DegV family
CBI37_RS11235	COG3479	Phenolic acid decarboxylase
CBI37_RS11240	COG1695	Transcriptional regulator
CBI37_RS11250	COG1012	belongs to the aldehyde dehydrogenase family
CBI37_RS11250	COG1454	alcohol dehydrogenase
CBI37_RS11255	COG1609	Transcriptional regulator
CBI37_RS11265	COG1869	D-ribose catabolic process
CBI37_RS11270	COG4975	Glucose uptake
CBI37_RS11290	COG3730	PTS system glucitol sorbitol-specific
CBI37_RS11295	COG3732	PTS system glucitol sorbitol-specific
CBI37_RS11310	COG2188	Transcriptional regulator
CBI37_RS11315	COG1132	(ABC) transporter
CBI37_RS11320	COG1132	(ABC) transporter
CBI37_RS11325	COG2207	Transcriptional regulator
CBI37_RS11325	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CBI37_RS11340	COG0395	ABC-type sugar transport system, permease component
CBI37_RS11345	COG1653	transport
CBI37_RS11350	COG0366	Alpha amylase catalytic
CBI37_RS11360	COG2972	Histidine kinase
CBI37_RS11365	COG2207	Transcriptional regulator
CBI37_RS11365	COG4753	response regulator
CBI37_RS11375	COG3842	ATPase activity
CBI37_RS11385	COG2188	Transcriptional regulator
CBI37_RS11395	COG0383	alpha-mannosidase activity
CBI37_RS11400	COG1940	carbohydrate kinase activity
CBI37_RS11405	COG2723	6-phospho-beta-galactosidase activity
CBI37_RS11445	COG1609	Transcriptional regulator
CBI37_RS11445	COG2207	Transcriptional regulator
CBI37_RS11525	COG1349	DNA-binding transcription factor activity
CBI37_RS11530	COG2207	Transcriptional regulator
CBI37_RS11535	COG2814	Major facilitator Superfamily
CBI37_RS11540	COG1070	Carbohydrate kinase
CBI37_RS11545	COG3254	rhamnose metabolic process
CBI37_RS11550	COG4806	L-rhamnose isomerase
CBI37_RS11555	COG0235	Class ii aldolase
CBI37_RS11570	COG0028	Belongs to the TPP enzyme family
CBI37_RS11575	COG1959	2 iron, 2 sulfur cluster binding
CBI37_RS11580	COG0028	Belongs to the TPP enzyme family
CBI37_RS11585	COG1304	FMN binding
CBI37_RS11600	COG4512	PFAM Accessory gene regulator B
CBI37_RS11620	COG1393	Belongs to the ArsC family
CBI37_RS11630	COG2261	transglycosylase associated protein
CBI37_RS11660	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
CBI37_RS11665	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CBI37_RS11685	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CBI37_RS11705	COG1737	Transcriptional regulator
CBI37_RS11710	COG1609	Transcriptional regulator
CBI37_RS11730	COG2160	L-arabinose isomerase activity
CBI37_RS11735	COG0110	maltose O-acetyltransferase activity
CBI37_RS11745	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
CBI37_RS11750	COG1349	DNA-binding transcription factor activity
CBI37_RS11760	COG3414	Phosphotransferase system galactitol-specific IIB component
CBI37_RS11765	COG3775	system Galactitol-specific IIC component
CBI37_RS11780	COG3711	transcriptional antiterminator
CBI37_RS11800	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CBI37_RS11815	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
CBI37_RS11830	COG2211	Major facilitator Superfamily
CBI37_RS11850	COG2190	(PTS) system
CBI37_RS11850	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CBI37_RS11850	COG1263	PTS System
CBI37_RS11855	COG2723	6-phospho-beta-galactosidase activity
CBI37_RS11860	COG2723	6-phospho-beta-galactosidase activity
CBI37_RS11865	COG3711	transcriptional antiterminator
CBI37_RS11875	COG2723	6-phospho-beta-galactosidase activity
CBI37_RS11885	COG2971	BadF BadG BcrA BcrD
CBI37_RS11890	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
CBI37_RS11895	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CBI37_RS11900	COG2188	Transcriptional regulator
CBI37_RS11905	COG2267	carboxylic ester hydrolase activity
CBI37_RS11915	COG2271	Major facilitator Superfamily
CBI37_RS11930	COG1028	Short-chain dehydrogenase reductase Sdr
CBI37_RS11945	COG2271	Major facilitator Superfamily
CBI37_RS11950	COG0583	DNA-binding transcription factor activity
CBI37_RS11955	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CBI37_RS11960	COG0710	3-dehydroquinate dehydratase activity
CBI37_RS11980	COG0667	Aldo Keto reductase
CBI37_RS11985	COG1609	Transcriptional regulator
CBI37_RS11990	COG2017	converts alpha-aldose to the beta-anomer
CBI37_RS11995	COG2211	Major facilitator Superfamily
CBI37_RS11995	COG2190	(PTS) system
CBI37_RS12015	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
CBI37_RS12020	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CBI37_RS12025	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
CBI37_RS12030	COG1609	Transcriptional regulator
CBI37_RS12035	COG2944	sequence-specific DNA binding
CBI37_RS12040	COG2184	nucleotidyltransferase activity
CBI37_RS12060	COG0477	Major facilitator Superfamily
CBI37_RS12070	COG1609	Transcriptional regulator
CBI37_RS12075	COG1874	Beta-galactosidase
CBI37_RS12085	COG1114	Component of the transport system for branched-chain amino acids
CBI37_RS12095	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
CBI37_RS12145	COG0446	pyridine nucleotide-disulphide oxidoreductase
CBI37_RS12170	COG3590	peptidase
CBI37_RS12175	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CBI37_RS12195	COG1937	Protein conserved in bacteria
CBI37_RS12200	COG3118	belongs to the thioredoxin family
CBI37_RS12205	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
CBI37_RS12210	COG2217	Heavy metal translocating P-type atpase
CBI37_RS12230	COG2226	methyltransferase
CBI37_RS12280	COG0076	glutamate decarboxylase activity
CBI37_RS12305	COG2207	Transcriptional regulator
CBI37_RS12340	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
CBI37_RS12345	COG1968	undecaprenyl-diphosphatase activity
CBI37_RS12365	COG0656	L-ascorbic acid biosynthetic process
CBI37_RS12375	COG0737	Belongs to the 5'-nucleotidase family
CBI37_RS12440	COG0477	Major facilitator Superfamily
CBI37_RS12465	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
CBI37_RS12480	COG0697	spore germination
CBI37_RS12505	COG0071	Belongs to the small heat shock protein (HSP20) family
CBI37_RS12520	COG1194	a g-specific adenine glycosylase
CBI37_RS12530	COG3189	MarR family transcriptional regulator
CBI37_RS12535	COG1393	Belongs to the ArsC family
CBI37_RS12550	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
CBI37_RS12560	COG1113	amino acid transport
CBI37_RS12565	COG1757	Na H antiporter
CBI37_RS12580	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CBI37_RS12585	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
CBI37_RS12595	COG2315	Protein conserved in bacteria
CBI37_RS12605	COG2217	Heavy metal translocating P-type atpase
CBI37_RS12640	COG4989	oxidoreductase activity
CBI37_RS12645	COG2151	metal-sulfur cluster biosynthetic enzyme
CBI37_RS12655	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
CBI37_RS12660	COG1882	Formate acetyltransferase
CBI37_RS12665	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CBI37_RS12695	COG2814	Major facilitator Superfamily
CBI37_RS12700	COG0803	Belongs to the bacterial solute-binding protein 9 family
CBI37_RS12720	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CBI37_RS12725	COG0302	gtp cyclohydrolase
CBI37_RS12735	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
CBI37_RS12770	COG0640	Transcriptional regulator
CBI37_RS12775	COG1272	protein, Hemolysin III
CBI37_RS12790	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
CBI37_RS12795	COG0628	permease
CBI37_RS12800	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
CBI37_RS12815	COG3158	transport of potassium into the cell
CBI37_RS12820	COG0531	amino acid
CBI37_RS12830	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CBI37_RS12835	COG2365	Tyrosine phosphatase family
CBI37_RS12840	COG0516	GMP reductase activity
CBI37_RS12845	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
CBI37_RS12850	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CBI37_RS12865	COG1929	Belongs to the glycerate kinase type-1 family
CBI37_RS12875	COG1562	ergosterol biosynthetic process
CBI37_RS12880	COG1233	COG1233 Phytoene dehydrogenase and related
CBI37_RS12885	COG2738	Putative neutral zinc metallopeptidase
CBI37_RS12895	COG1307	EDD domain protein, DegV family
CBI37_RS12905	COG1380	Effector of murein hydrolase LrgA
CBI37_RS12930	COG0735	belongs to the Fur family
CBI37_RS12960	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CBI37_RS12960	COG1263	PTS System
CBI37_RS12960	COG2190	(PTS) system
CBI37_RS12975	COG3711	transcriptional antiterminator
CBI37_RS12975	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CBI37_RS12980	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CBI37_RS12980	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CBI37_RS12980	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CBI37_RS12985	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CBI37_RS12990	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CBI37_RS12990	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CBI37_RS12990	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CBI37_RS12995	COG0383	alpha-mannosidase activity
CBI37_RS13005	COG0561	phosphatase activity
CBI37_RS13020	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CBI37_RS13025	COG4619	ABC transporter
CBI37_RS13030	COG0390	transport system, permease component
CBI37_RS13045	COG1609	Transcriptional regulator
CBI37_RS13050	COG0366	Alpha amylase catalytic
CBI37_RS13055	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CBI37_RS13055	COG2190	(PTS) system
CBI37_RS13055	COG1263	PTS System
CBI37_RS13080	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CBI37_RS13085	COG1126	abc transporter atp-binding protein
CBI37_RS13090	COG0765	amino acid transport
CBI37_RS13095	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CBI37_RS13100	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CBI37_RS13105	COG0583	DNA-binding transcription factor activity
CBI37_RS13120	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CBI37_RS13125	COG0357	Ribosomal RNA small subunit methyltransferase G
CBI37_RS13135	COG1192	Involved in chromosome partitioning
CBI37_RS13140	COG1475	DNA binding
CBI37_RS13145	COG4481	Protein conserved in bacteria
CBI37_RS13150	COG0012	GTP binding
CBI37_RS13165	COG0517	IMP dehydrogenase activity
CBI37_RS13165	COG0516	GMP reductase activity
CBI37_RS13170	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CBI37_RS13190	COG1686	Belongs to the peptidase S11 family
CBI37_RS13195	COG1247	-acetyltransferase
CBI37_RS13235	COG2815	serine threonine protein kinase
CBI37_RS13235	COG0515	serine threonine protein kinase
CBI37_RS13245	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CBI37_RS13255	COG1940	carbohydrate kinase activity
CBI37_RS13255	COG1846	Transcriptional regulator
CBI37_RS13260	COG0628	permease
CBI37_RS13265	COG0588	phosphoglycerate mutase activity
CBI37_RS13300	COG0477	Major facilitator Superfamily
CBI37_RS13315	COG0656	L-ascorbic acid biosynthetic process
CBI37_RS13320	COG1376	ErfK ybiS ycfS ynhG family protein
CBI37_RS13340	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
CBI37_RS13350	COG1136	(ABC) transporter
CBI37_RS13350	COG0577	efflux transmembrane transporter activity
CBI37_RS13375	COG0693	protein deglycase activity
CBI37_RS13395	COG0789	Transcriptional regulator
CBI37_RS13415	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CBI37_RS13420	COG2723	6-phospho-beta-galactosidase activity
CBI37_RS13430	COG0783	Belongs to the Dps family
CBI37_RS13440	COG1053	succinate dehydrogenase
CBI37_RS13450	COG2816	NAD+ diphosphatase activity
CBI37_RS13460	COG0481	GTPase activity
CBI37_RS13495	COG1028	Short-chain dehydrogenase reductase Sdr
CBI37_RS13500	COG0110	maltose O-acetyltransferase activity
CBI37_RS13505	COG4221	oxidoreductase activity
CBI37_RS13515	COG1309	transcriptional regulator
CBI37_RS13520	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CBI37_RS13525	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CBI37_RS13530	COG1120	ATPase activity
CBI37_RS13535	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CBI37_RS13545	COG0477	Major facilitator Superfamily
CBI37_RS13550	COG4989	oxidoreductase activity
CBI37_RS13570	COG0300	oxidoreductase activity
CBI37_RS13575	COG1733	regulation of RNA biosynthetic process
CBI37_RS13590	COG1012	belongs to the aldehyde dehydrogenase family
CBI37_RS13600	COG1309	transcriptional regulator
CBI37_RS13615	COG3279	Response regulator of the LytR AlgR family
CBI37_RS13620	COG0367	asparagine synthase
CBI37_RS13630	COG2814	Major facilitator Superfamily
CBI37_RS13635	COG1733	regulation of RNA biosynthetic process
CBI37_RS13640	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CBI37_RS13680	COG1063	alcohol dehydrogenase
CBI37_RS13740	COG2217	Heavy metal translocating P-type atpase
CBI37_RS13770	COG0531	amino acid
CBI37_RS13785	COG1028	Short-chain dehydrogenase reductase Sdr
CBI37_RS13790	COG1473	amidohydrolase
CBI37_RS13800	COG1132	(ABC) transporter
CBI37_RS13850	COG4221	oxidoreductase activity
CBI37_RS13865	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CBI37_RS13890	COG0803	Belongs to the bacterial solute-binding protein 9 family
CBI37_RS13910	COG0741	lytic transglycosylase activity
CBI37_RS13915	COG0789	Transcriptional regulator
CBI37_RS13925	COG2723	6-phospho-beta-galactosidase activity
CBI37_RS13930	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CBI37_RS13935	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CBI37_RS13970	COG0577	efflux transmembrane transporter activity
CBI37_RS13970	COG1136	(ABC) transporter
CBI37_RS13980	COG0640	Transcriptional regulator
CBI37_RS14000	COG1914	H( )-stimulated, divalent metal cation uptake system
CBI37_RS14010	COG2246	polysaccharide biosynthetic process
CBI37_RS14015	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CBI37_RS14015	COG5549	protein import
CBI37_RS14030	COG0559	Belongs to the binding-protein-dependent transport system permease family
CBI37_RS14045	COG0410	ABC transporter
CBI37_RS14050	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
CBI37_RS14050	COG0617	tRNA 3'-terminal CCA addition
CBI37_RS14050	COG3620	sequence-specific DNA binding
CBI37_RS14080	COG4120	Belongs to the binding-protein-dependent transport system permease family
CBI37_RS14090	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CBI37_RS14090	COG2190	(PTS) system
CBI37_RS14090	COG1263	PTS System
CBI37_RS14095	COG0778	Nitroreductase
CBI37_RS14110	COG1940	carbohydrate kinase activity
CBI37_RS14135	COG0697	spore germination
CBI37_RS14195	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
CBI37_RS14205	COG0583	DNA-binding transcription factor activity
CBI37_RS14230	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CBI37_RS14240	COG0242	peptide deformylase activity
CBI37_RS14250	COG1328	CTP reductase activity
CBI37_RS14260	COG2200	EAL domain
CBI37_RS14300	COG2270	Major facilitator Superfamily
CBI37_RS14315	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CBI37_RS14325	COG0561	phosphatase activity
CBI37_RS14330	COG0488	(ABC) transporter
CBI37_RS14355	COG0640	Transcriptional regulator
CBI37_RS14365	COG1511	domain protein
CBI37_RS14365	COG1511	domain protein
CBI37_RS14380	COG2814	Major facilitator Superfamily
CBI37_RS14385	COG1132	(ABC) transporter
CBI37_RS14390	COG1132	(ABC) transporter
CBI37_RS14395	COG0667	Aldo Keto reductase
CBI37_RS14405	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
CBI37_RS14420	COG1011	Hydrolase
CBI37_RS14425	COG0110	maltose O-acetyltransferase activity
CBI37_RS14430	COG0589	response to stress
CBI37_RS14450	COG0656	L-ascorbic acid biosynthetic process
CBI37_RS14455	COG4221	oxidoreductase activity
CBI37_RS14475	COG0583	DNA-binding transcription factor activity
CBI37_RS14480	COG0656	L-ascorbic acid biosynthetic process
CBI37_RS14510	COG0656	L-ascorbic acid biosynthetic process
CBI37_RS14515	COG1028	Short-chain dehydrogenase reductase Sdr
CBI37_RS14520	COG1063	alcohol dehydrogenase
CBI37_RS14530	COG0583	DNA-binding transcription factor activity
CBI37_RS14555	COG0456	acetyltransferase
CBI37_RS14580	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CBI37_RS14600	COG0789	Transcriptional regulator
CBI37_RS14615	COG4221	oxidoreductase activity
CBI37_RS14625	COG4152	abc transporter atp-binding protein
CBI37_RS14635	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CBI37_RS14650	COG0438	transferase activity, transferring glycosyl groups
CBI37_RS14660	COG0583	DNA-binding transcription factor activity
CBI37_RS14665	COG2855	membrane
CBI37_RS14670	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CBI37_RS14680	COG2814	Major facilitator Superfamily
CBI37_RS14690	COG2814	Major facilitator Superfamily
CBI37_RS14730	COG1136	(ABC) transporter
CBI37_RS14735	COG0577	efflux transmembrane transporter activity
CBI37_RS14750	COG0789	Transcriptional regulator
CBI37_RS14750	COG4978	Transcriptional regulator
CBI37_RS14755	COG1811	Na channel or pump
CBI37_RS14765	COG4990	cell redox homeostasis
CBI37_RS14780	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CBI37_RS14785	COG4720	Psort location CytoplasmicMembrane, score
CBI37_RS14830	COG0531	amino acid
CBI37_RS14835	COG0710	3-dehydroquinate dehydratase activity
CBI37_RS14855	COG0716	FMN binding
CBI37_RS14880	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CBI37_RS14885	COG0561	phosphatase activity
CBI37_RS14900	COG1216	Glycosyl transferase, family 2
CBI37_RS14905	COG2188	Transcriptional regulator
CBI37_RS14910	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CBI37_RS14915	COG1447	Phosphotransferase system cellobiose-specific component IIA
CBI37_RS14920	COG2723	6-phospho-beta-galactosidase activity
CBI37_RS14925	COG2723	6-phospho-beta-galactosidase activity
CBI37_RS14930	COG3048	D-serine ammonia-lyase activity
CBI37_RS14935	COG1131	(ABC) transporter
CBI37_RS14945	COG1309	transcriptional regulator
CBI37_RS14950	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
CBI37_RS14955	COG1827	regulation of RNA biosynthetic process
CBI37_RS14990	COG0494	nUDIX hydrolase
CBI37_RS14995	COG0110	maltose O-acetyltransferase activity
CBI37_RS15005	COG0561	phosphatase activity
CBI37_RS15015	COG0366	Alpha amylase catalytic
CBI37_RS15035	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
CBI37_RS15055	COG2246	polysaccharide biosynthetic process
CBI37_RS15065	COG0589	response to stress
CBI37_RS15075	COG1131	(ABC) transporter
CBI37_RS15080	COG1725	Transcriptional regulator
CBI37_RS15095	COG1136	(ABC) transporter
CBI37_RS15120	COG2365	Tyrosine phosphatase family
CBI37_RS15125	COG0095	Lipoate-protein ligase
CBI37_RS15130	COG0431	NADPH-dependent FMN reductase
CBI37_RS15130	COG1053	succinate dehydrogenase
CBI37_RS15130	COG3976	FMN-binding domain protein
CBI37_RS15135	COG3976	FMN-binding domain protein
CBI37_RS15135	COG1053	succinate dehydrogenase
CBI37_RS15135	COG0431	NADPH-dependent FMN reductase
CBI37_RS15145	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
CBI37_RS15150	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
CBI37_RS15155	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CBI37_RS15160	COG0047	phosphoribosylformylglycinamidine synthase activity
CBI37_RS15165	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CBI37_RS15175	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
CBI37_RS15180	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
CBI37_RS15185	COG0138	bifunctional purine biosynthesis protein purh
CBI37_RS15190	COG0151	Belongs to the GarS family
CBI37_RS15200	COG1215	transferase activity, transferring glycosyl groups
CBI37_RS15220	COG2252	PERMEase
CBI37_RS15225	COG2233	PERMEase
CBI37_RS15230	COG2508	Transcriptional regulator
CBI37_RS15235	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
CBI37_RS15240	COG0540	Belongs to the ATCase OTCase family
CBI37_RS15245	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
CBI37_RS15250	COG0505	Belongs to the CarA family
CBI37_RS15255	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
CBI37_RS15260	COG0167	dihydroorotate dehydrogenase activity
CBI37_RS15265	COG0284	orotidine-5'-phosphate decarboxylase activity
CBI37_RS15270	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
CBI37_RS15280	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
CBI37_RS15285	COG1074	ATP-dependent DNA helicase activity
CBI37_RS15295	COG0702	epimerase
CBI37_RS15300	COG0583	DNA-binding transcription factor activity
CBI37_RS15320	COG0436	Aminotransferase
CBI37_RS15325	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CBI37_RS15335	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
CBI37_RS15345	COG0604	alcohol dehydrogenase
CBI37_RS15350	COG0789	Transcriptional regulator
CBI37_RS15355	COG2814	Major facilitator Superfamily
CBI37_RS15360	COG0025	NhaP-type Na H and K H
CBI37_RS15365	COG1780	Probably involved in ribonucleotide reductase function
CBI37_RS15370	COG1253	flavin adenine dinucleotide binding
CBI37_RS15400	COG1418	mRNA catabolic process
CBI37_RS15410	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CBI37_RS15415	COG2188	Transcriptional regulator
CBI37_RS15425	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
CBI37_RS15440	COG1396	sequence-specific DNA binding
CBI37_RS15445	COG0564	pseudouridine synthase activity
CBI37_RS15450	COG0589	response to stress
CBI37_RS15455	COG2188	Transcriptional regulator
CBI37_RS15460	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CBI37_RS15465	COG3715	PTS system
CBI37_RS15470	COG3716	PTS system mannose fructose sorbose family IID component
CBI37_RS15480	COG1705	Flagellar rod assembly protein muramidase FlgJ
CBI37_RS15485	COG0095	Lipoate-protein ligase
CBI37_RS15515	COG0626	cystathionine gamma-synthase activity
CBI37_RS15520	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CBI37_RS15525	COG1073	alpha beta
CBI37_RS15535	COG0028	Belongs to the TPP enzyme family
CBI37_RS15575	COG1725	Transcriptional regulator
CBI37_RS15580	COG1131	(ABC) transporter
CBI37_RS15590	COG1335	isochorismatase
CBI37_RS15595	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
CBI37_RS15600	COG0025	NhaP-type Na H and K H
CBI37_RS15605	COG0673	inositol 2-dehydrogenase activity
CBI37_RS15610	COG0673	inositol 2-dehydrogenase activity
CBI37_RS15615	COG1737	Transcriptional regulator
CBI37_RS15620	COG1609	Transcriptional regulator
CBI37_RS15640	COG1882	Formate acetyltransferase
CBI37_RS15645	COG1349	DNA-binding transcription factor activity
CBI37_RS15660	COG4975	Glucose uptake
CBI37_RS15665	COG0328	RNA-DNA hybrid ribonuclease activity
CBI37_RS15675	COG0778	Nitroreductase
CBI37_RS15680	COG2326	polyphosphate kinase activity
CBI37_RS15685	COG4932	domain protein
CBI37_RS15695	COG0492	ferredoxin-NADP+ reductase activity
CBI37_RS15705	COG0584	glycerophosphoryl diester phosphodiesterase
CBI37_RS15710	COG1368	sulfuric ester hydrolase activity
CBI37_RS15730	COG3548	integral membrane protein
CBI37_RS15745	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CBI37_RS15770	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
CBI37_RS15775	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
CBI37_RS15780	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
CBI37_RS15785	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
CBI37_RS15790	COG0131	Imidazoleglycerol-phosphate dehydratase
CBI37_RS15795	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
CBI37_RS15800	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
CBI37_RS15805	COG0107	imidazoleglycerol-phosphate synthase activity
CBI37_RS15810	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
CBI37_RS15815	COG0140	phosphoribosyl-ATP diphosphatase activity
CBI37_RS15820	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CBI37_RS15825	COG0110	maltose O-acetyltransferase activity
CBI37_RS15830	COG0861	Integral membrane protein TerC family
CBI37_RS15835	COG2084	Dehydrogenase
CBI37_RS15850	COG0446	pyridine nucleotide-disulphide oxidoreductase
CBI37_RS15860	COG4120	Belongs to the binding-protein-dependent transport system permease family
CBI37_RS15875	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
CBI37_RS15880	COG2873	o-acetylhomoserine
CBI37_RS15890	COG1307	EDD domain protein, DegV family
CBI37_RS15895	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CBI37_RS15900	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CBI37_RS15900	COG1263	PTS System
CBI37_RS15900	COG2190	(PTS) system
CBI37_RS15925	COG0488	(ABC) transporter
CBI37_RS15945	COG1522	sequence-specific DNA binding
CBI37_RS15950	COG0791	NLP P60 protein
CBI37_RS15970	COG0477	Major facilitator Superfamily
CBI37_RS15995	COG3830	Belongs to the UPF0237 family
CBI37_RS16000	COG2848	UPF0210 protein
CBI37_RS16005	COG0745	RESPONSE REGULATOR receiver
CBI37_RS16010	COG3850	Histidine kinase
CBI37_RS16010	COG5002	protein histidine kinase activity
CBI37_RS16015	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
CBI37_RS16025	COG0166	Belongs to the GPI family
CBI37_RS16060	COG1396	sequence-specific DNA binding
CBI37_RS16065	COG3620	sequence-specific DNA binding
CBI37_RS16095	COG3723	Recombinational DNA repair protein, rece pathway
CBI37_RS16185	COG3728	DNA packaging
CBI37_RS16185	COG5484	DNA packaging
CBI37_RS16245	COG5492	domain, Protein
CBI37_RS16245	COG4932	domain protein