locus-tag	class	description
HUE89_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
HUE89_RS00015	COG2501	S4 domain
HUE89_RS00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HUE89_RS00025	COG0187	DNA topoisomerase II activity
HUE89_RS00030	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HUE89_RS00035	COG0360	Binds together with S18 to 16S ribosomal RNA
HUE89_RS00040	COG0629	single-stranded DNA binding
HUE89_RS00045	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HUE89_RS00055	COG0359	binds to the 23S rRNA
HUE89_RS00060	COG0305	Participates in initiation and elongation during chromosome replication
HUE89_RS00070	COG1307	EDD domain protein, DegV family
HUE89_RS00075	COG1940	carbohydrate kinase activity
HUE89_RS00080	COG3237	CsbD-like
HUE89_RS00085	COG2261	transglycosylase associated protein
HUE89_RS00105	COG0640	Transcriptional regulator
HUE89_RS00175	COG4690	dipeptidase activity
HUE89_RS00190	COG2096	Adenosyltransferase
HUE89_RS00205	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HUE89_RS00210	COG0628	permease
HUE89_RS00235	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HUE89_RS00250	COG1011	Hydrolase
HUE89_RS00260	COG0561	phosphatase activity
HUE89_RS00270	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HUE89_RS00275	COG0708	Exodeoxyribonuclease III
HUE89_RS00280	COG0531	amino acid
HUE89_RS00285	COG0513	Belongs to the DEAD box helicase family
HUE89_RS00330	COG0583	DNA-binding transcription factor activity
HUE89_RS00355	COG1442	glycosyl transferase family 8
HUE89_RS00370	COG1132	(ABC) transporter
HUE89_RS00395	COG0745	RESPONSE REGULATOR receiver
HUE89_RS00400	COG5002	protein histidine kinase activity
HUE89_RS00415	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
HUE89_RS00420	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HUE89_RS00425	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
HUE89_RS00455	COG2267	carboxylic ester hydrolase activity
HUE89_RS00465	COG1122	ATPase activity
HUE89_RS00475	COG0501	Belongs to the peptidase M48B family
HUE89_RS00480	COG1704	LemA family
HUE89_RS00485	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
HUE89_RS00515	COG1215	transferase activity, transferring glycosyl groups
HUE89_RS00540	COG1126	abc transporter atp-binding protein
HUE89_RS00545	COG0765	amino acid transport
HUE89_RS00550	COG2094	Belongs to the DNA glycosylase MPG family
HUE89_RS00555	COG3189	MarR family transcriptional regulator
HUE89_RS00560	COG0861	Integral membrane protein TerC family
HUE89_RS00570	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
HUE89_RS00580	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HUE89_RS00590	COG0328	RNA-DNA hybrid ribonuclease activity
HUE89_RS00600	COG1216	Glycosyl transferase, family 2
HUE89_RS00620	COG2801	Transposase and inactivated derivatives
HUE89_RS00640	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HUE89_RS00655	COG0765	amino acid transport
HUE89_RS00660	COG1126	abc transporter atp-binding protein
HUE89_RS00670	COG1181	Belongs to the D-alanine--D-alanine ligase family
HUE89_RS00715	COG2365	Tyrosine phosphatase family
HUE89_RS00720	COG0589	response to stress
HUE89_RS00730	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
HUE89_RS00740	COG3639	organic phosphonate transmembrane transporter activity
HUE89_RS00745	COG0519	Catalyzes the synthesis of GMP from XMP
HUE89_RS00760	COG0367	asparagine synthase
HUE89_RS00775	COG0602	queuosine metabolic process
HUE89_RS00780	COG2151	metal-sulfur cluster biosynthetic enzyme
HUE89_RS00790	COG2814	Major facilitator Superfamily
HUE89_RS00795	COG3590	peptidase
HUE89_RS00840	COG1388	LysM domain
HUE89_RS00840	COG1705	Flagellar rod assembly protein muramidase FlgJ
HUE89_RS00850	COG0475	glutathione-regulated potassium exporter activity
HUE89_RS00850	COG0569	domain protein
HUE89_RS00855	COG0673	inositol 2-dehydrogenase activity
HUE89_RS00870	COG0588	phosphoglycerate mutase activity
HUE89_RS00875	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
HUE89_RS00885	COG1316	TRANSCRIPTIONal
HUE89_RS00890	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
HUE89_RS00895	COG1368	sulfuric ester hydrolase activity
HUE89_RS00905	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HUE89_RS00920	COG3579	cysteine-type endopeptidase activity
HUE89_RS00925	COG1418	mRNA catabolic process
HUE89_RS00930	COG4166	transmembrane transport
HUE89_RS00935	COG4166	transmembrane transport
HUE89_RS00940	COG0517	IMP dehydrogenase activity
HUE89_RS00940	COG0516	GMP reductase activity
HUE89_RS00945	COG0601	transmembrane transport
HUE89_RS00950	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HUE89_RS00955	COG0444	Belongs to the ABC transporter superfamily
HUE89_RS00960	COG4608	Belongs to the ABC transporter superfamily
HUE89_RS00965	COG3579	cysteine-type endopeptidase activity
HUE89_RS00975	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
HUE89_RS01000	COG2131	deaminase
HUE89_RS01010	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
HUE89_RS01015	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HUE89_RS01015	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HUE89_RS01020	COG0084	hydrolase, TatD family'
HUE89_RS01030	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
HUE89_RS01035	COG4466	Protein conserved in bacteria
HUE89_RS01040	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HUE89_RS01045	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
HUE89_RS01070	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HUE89_RS01075	COG2723	6-phospho-beta-galactosidase activity
HUE89_RS01080	COG1737	Transcriptional regulator
HUE89_RS01085	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HUE89_RS01100	COG1078	dGTPase activity
HUE89_RS01110	COG3343	RNA polymerase activity
HUE89_RS01115	COG0504	CTP synthase activity
HUE89_RS01120	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HUE89_RS01145	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HUE89_RS01155	COG1396	sequence-specific DNA binding
HUE89_RS01160	COG0519	Catalyzes the synthesis of GMP from XMP
HUE89_RS01170	COG1131	(ABC) transporter
HUE89_RS01190	COG0456	acetyltransferase
HUE89_RS01205	COG2814	Major facilitator Superfamily
HUE89_RS01225	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HUE89_RS01255	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
HUE89_RS01260	COG0531	amino acid
HUE89_RS01265	COG0561	phosphatase activity
HUE89_RS01270	COG0366	Alpha amylase catalytic
HUE89_RS01275	COG0254	rRNA binding
HUE89_RS01280	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
HUE89_RS01290	COG0736	holo-[acyl-carrier-protein] synthase activity
HUE89_RS01295	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HUE89_RS01305	COG0039	L-malate dehydrogenase activity
HUE89_RS01310	COG0193	aminoacyl-tRNA hydrolase activity
HUE89_RS01315	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HUE89_RS01320	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
HUE89_RS01335	COG0037	tRNA processing
HUE89_RS01345	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
HUE89_RS01350	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HUE89_RS01355	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
HUE89_RS01375	COG1956	GAF domain-containing protein
HUE89_RS01380	COG0542	response to heat
HUE89_RS01385	COG0085	RNA polymerase activity
HUE89_RS01390	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HUE89_RS01400	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
HUE89_RS01405	COG0049	tRNA binding
HUE89_RS01410	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HUE89_RS01415	COG0051	transcription antitermination factor activity, RNA binding
HUE89_RS01420	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
HUE89_RS01425	COG0088	Forms part of the polypeptide exit tunnel
HUE89_RS01430	COG0089	rRNA binding
HUE89_RS01435	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HUE89_RS01445	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
HUE89_RS01450	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
HUE89_RS01455	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
HUE89_RS01460	COG0255	Belongs to the universal ribosomal protein uL29 family
HUE89_RS01465	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
HUE89_RS01470	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
HUE89_RS01475	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
HUE89_RS01480	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HUE89_RS01490	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
HUE89_RS01495	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
HUE89_RS01500	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
HUE89_RS01505	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
HUE89_RS01510	COG1841	ribosomal large subunit assembly
HUE89_RS01515	COG0200	Binds to the 23S rRNA
HUE89_RS01525	COG0563	adenylate kinase activity
HUE89_RS01530	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HUE89_RS01540	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HUE89_RS01545	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
HUE89_RS01550	COG0202	RNA polymerase activity
HUE89_RS01555	COG0203	ribosomal protein L17
HUE89_RS01560	COG1122	ATPase activity
HUE89_RS01565	COG1122	ATPase activity
HUE89_RS01570	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HUE89_RS01575	COG0101	tRNA pseudouridine synthase activity
HUE89_RS01580	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
HUE89_RS01590	COG0582	viral genome integration into host DNA
HUE89_RS01625	COG1002	Type II restriction enzyme, methylase subunits
HUE89_RS01650	COG1011	Hydrolase
HUE89_RS01665	COG1230	cation diffusion facilitator family transporter
HUE89_RS01670	COG0588	phosphoglycerate mutase activity
HUE89_RS01690	COG0756	dUTP diphosphatase activity
HUE89_RS01700	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HUE89_RS01705	COG0215	cysteine-tRNA ligase activity
HUE89_RS01710	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
HUE89_RS01715	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HUE89_RS01735	COG1070	Carbohydrate kinase
HUE89_RS01745	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HUE89_RS01750	COG0267	Belongs to the bacterial ribosomal protein bL33 family
HUE89_RS01760	COG0250	Participates in transcription elongation, termination and antitermination
HUE89_RS01765	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
HUE89_RS01770	COG0081	regulation of translation
HUE89_RS01780	COG0573	inorganic phosphate transmembrane transporter activity
HUE89_RS01785	COG0581	inorganic phosphate transmembrane transporter activity
HUE89_RS01790	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
HUE89_RS01795	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
HUE89_RS01800	COG0704	Plays a role in the regulation of phosphate uptake
HUE89_RS01805	COG0679	Auxin Efflux Carrier
HUE89_RS01815	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
HUE89_RS01820	COG0222	ribosome binding
HUE89_RS01830	COG2813	Specifically methylates the guanine in position
HUE89_RS01840	COG0590	tRNA wobble adenosine to inosine editing
HUE89_RS01850	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HUE89_RS01860	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
HUE89_RS01865	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
HUE89_RS01875	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HUE89_RS01880	COG3870	Protein conserved in bacteria
HUE89_RS01885	COG0470	DNA polymerase III
HUE89_RS01905	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
HUE89_RS01910	COG1214	PFAM Peptidase M22, glycoprotease
HUE89_RS01915	COG0456	acetyltransferase
HUE89_RS01920	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
HUE89_RS01925	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
HUE89_RS01935	COG2188	Transcriptional regulator
HUE89_RS01955	COG0488	(ABC) transporter
HUE89_RS01960	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
HUE89_RS01970	COG1621	beta-fructofuranosidase activity
HUE89_RS01975	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HUE89_RS01975	COG2190	(PTS) system
HUE89_RS01975	COG1263	PTS System
HUE89_RS01995	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
HUE89_RS02000	COG0459	protein refolding
HUE89_RS02005	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
HUE89_RS02010	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
HUE89_RS02015	COG0632	four-way junction helicase activity
HUE89_RS02020	COG2255	four-way junction helicase activity
HUE89_RS02030	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
HUE89_RS02035	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HUE89_RS02040	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
HUE89_RS02045	COG0513	Belongs to the DEAD box helicase family
HUE89_RS02050	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HUE89_RS02055	COG4472	Bacterial protein of unknown function (DUF965)
HUE89_RS02060	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
HUE89_RS02065	COG3906	Belongs to the UPF0473 family
HUE89_RS02070	COG1193	negative regulation of DNA recombination
HUE89_RS02075	COG3118	belongs to the thioredoxin family
HUE89_RS02080	COG1970	mechanosensitive ion channel activity
HUE89_RS02090	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
HUE89_RS02095	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
HUE89_RS02100	COG0668	transmembrane transport
HUE89_RS02115	COG0006	proline dipeptidase activity
HUE89_RS02125	COG0584	glycerophosphoryl diester phosphodiesterase
HUE89_RS02135	COG0737	Belongs to the 5'-nucleotidase family
HUE89_RS02145	COG0647	UMP catabolic process
HUE89_RS02155	COG0586	Pfam SNARE associated Golgi protein
HUE89_RS02160	COG0492	ferredoxin-NADP+ reductase activity
HUE89_RS02270	COG0494	nUDIX hydrolase
HUE89_RS02340	COG0438	transferase activity, transferring glycosyl groups
HUE89_RS02345	COG0438	transferase activity, transferring glycosyl groups
HUE89_RS02355	COG1368	sulfuric ester hydrolase activity
HUE89_RS02365	COG0557	exoribonuclease II activity
HUE89_RS02370	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
HUE89_RS02400	COG3715	PTS system
HUE89_RS02405	COG3716	PTS system mannose fructose sorbose family IID component
HUE89_RS02415	COG0583	DNA-binding transcription factor activity
HUE89_RS02420	COG0110	maltose O-acetyltransferase activity
HUE89_RS02425	COG1113	amino acid transport
HUE89_RS02430	COG1012	belongs to the aldehyde dehydrogenase family
HUE89_RS02430	COG1454	alcohol dehydrogenase
HUE89_RS02435	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
HUE89_RS02440	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HUE89_RS02450	COG0494	nUDIX hydrolase
HUE89_RS02470	COG1205	dead DEAH box helicase
HUE89_RS02470	COG1111	helicase
HUE89_RS02480	COG0004	ammonium transporteR
HUE89_RS02570	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HUE89_RS02590	COG0588	phosphoglycerate mutase activity
HUE89_RS02595	COG0588	phosphoglycerate mutase activity
HUE89_RS02605	COG0584	glycerophosphoryl diester phosphodiesterase
HUE89_RS02615	COG1609	Transcriptional regulator
HUE89_RS02625	COG1175	transmembrane transport
HUE89_RS02630	COG0395	ABC-type sugar transport system, permease component
HUE89_RS02635	COG1621	beta-fructofuranosidase activity
HUE89_RS02640	COG3842	ATPase activity
HUE89_RS02645	COG0366	Alpha amylase catalytic
HUE89_RS02690	COG2188	Transcriptional regulator
HUE89_RS02700	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
HUE89_RS02710	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HUE89_RS02725	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
HUE89_RS02740	COG3091	SprT-like family
HUE89_RS02750	COG1705	Flagellar rod assembly protein muramidase FlgJ
HUE89_RS02760	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HUE89_RS02765	COG4851	CamS sex pheromone cAM373 precursor
HUE89_RS02770	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HUE89_RS02775	COG0154	amidase activity
HUE89_RS02780	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HUE89_RS02785	COG1597	lipid kinase activity
HUE89_RS02790	COG0670	Belongs to the BI1 family
HUE89_RS02805	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HUE89_RS02820	COG2217	Heavy metal translocating P-type atpase
HUE89_RS02830	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HUE89_RS02835	COG1573	uracil-dna glycosylase
HUE89_RS02890	COG2814	Major facilitator Superfamily
HUE89_RS02900	COG1309	transcriptional regulator
HUE89_RS02905	COG4716	Myosin-crossreactive antigen
HUE89_RS02920	COG0656	L-ascorbic acid biosynthetic process
HUE89_RS02950	COG2814	Major facilitator Superfamily
HUE89_RS02955	COG2814	Major facilitator Superfamily
HUE89_RS02970	COG0488	(ABC) transporter
HUE89_RS02980	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HUE89_RS02990	COG1132	(ABC) transporter
HUE89_RS02995	COG1132	(ABC) transporter
HUE89_RS03005	COG0572	uridine kinase
HUE89_RS03015	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HUE89_RS03020	COG0765	amino acid transport
HUE89_RS03025	COG0765	amino acid transport
HUE89_RS03055	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
HUE89_RS03060	COG3158	transport of potassium into the cell
HUE89_RS03070	COG2188	Transcriptional regulator
HUE89_RS03090	COG0561	phosphatase activity
HUE89_RS03100	COG1132	(ABC) transporter
HUE89_RS03115	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
HUE89_RS03140	COG0561	phosphatase activity
HUE89_RS03145	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HUE89_RS03145	COG1263	PTS System
HUE89_RS03150	COG1737	Transcriptional regulator
HUE89_RS03160	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HUE89_RS03160	COG2190	(PTS) system
HUE89_RS03160	COG1263	PTS System
HUE89_RS03175	COG1253	flavin adenine dinucleotide binding
HUE89_RS03185	COG2801	Transposase and inactivated derivatives
HUE89_RS03190	COG0531	amino acid
HUE89_RS03200	COG0513	Belongs to the DEAD box helicase family
HUE89_RS03205	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HUE89_RS03215	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
HUE89_RS03225	COG0716	FMN binding
HUE89_RS03230	COG0024	Methionine aminopeptidase
HUE89_RS03235	COG1295	ribonuclease BN
HUE89_RS03240	COG1210	Utp--glucose-1-phosphate uridylyltransferase
HUE89_RS03245	COG0183	Belongs to the thiolase family
HUE89_RS03255	COG3425	synthase
HUE89_RS03265	COG1073	alpha beta
HUE89_RS03270	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HUE89_RS03295	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
HUE89_RS03305	COG0542	response to heat
HUE89_RS03315	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
HUE89_RS03325	COG1393	Belongs to the ArsC family
HUE89_RS03330	COG4862	establishment of competence for transformation
HUE89_RS03340	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HUE89_RS03350	COG2357	RelA SpoT domain protein
HUE89_RS03355	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HUE89_RS03360	COG0564	pseudouridine synthase activity
HUE89_RS03375	COG2706	6-phosphogluconolactonase activity
HUE89_RS03380	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
HUE89_RS03390	COG0628	permease
HUE89_RS03405	COG1674	ftsk spoiiie
HUE89_RS03415	COG0612	Peptidase, M16
HUE89_RS03420	COG1028	Short-chain dehydrogenase reductase Sdr
HUE89_RS03425	COG1426	Protein conserved in bacteria
HUE89_RS03430	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HUE89_RS03435	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
HUE89_RS03440	COG1418	mRNA catabolic process
HUE89_RS03445	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HUE89_RS03450	COG1739	Uncharacterized protein family UPF0029
HUE89_RS03455	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
HUE89_RS03470	COG0653	protein targeting
HUE89_RS03485	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
HUE89_RS03490	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
HUE89_RS03495	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
HUE89_RS03500	COG0492	ferredoxin-NADP+ reductase activity
HUE89_RS03505	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
HUE89_RS03510	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
HUE89_RS03515	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
HUE89_RS03520	COG0297	glycogen (starch) synthase activity
HUE89_RS03525	COG0058	SHG alpha-glucan phosphorylase activity
HUE89_RS03530	COG3103	Sh3 type 3 domain protein
HUE89_RS03530	COG0366	Alpha amylase catalytic
HUE89_RS03535	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HUE89_RS03540	COG0556	nucleotide-excision repair
HUE89_RS03545	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
HUE89_RS03555	COG1660	Displays ATPase and GTPase activities
HUE89_RS03560	COG0391	Required for morphogenesis under gluconeogenic growth conditions
HUE89_RS03565	COG1481	regulation of sporulation
HUE89_RS03570	COG0740	serine-type endopeptidase activity
HUE89_RS03580	COG0531	amino acid
HUE89_RS03590	COG2390	Transcriptional regulator
HUE89_RS03600	COG0126	phosphoglycerate kinase activity
HUE89_RS03605	COG0149	triose-phosphate isomerase activity
HUE89_RS03615	COG0561	phosphatase activity
HUE89_RS03620	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
HUE89_RS03625	COG0280	phosphate acetyltransferase
HUE89_RS03630	COG0802	atpase or kinase
HUE89_RS03640	COG0812	UDP-N-acetylmuramate dehydrogenase activity
HUE89_RS03645	COG3842	ATPase activity
HUE89_RS03650	COG1176	ABC-type spermidine putrescine transport system, permease component I
HUE89_RS03655	COG1176	ABC-type spermidine putrescine transport system, permease component I
HUE89_RS03670	COG4856	YbbR-like protein
HUE89_RS03675	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HUE89_RS03680	COG0561	phosphatase activity
HUE89_RS03685	COG0561	phosphatase activity
HUE89_RS03695	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HUE89_RS03700	COG1929	Belongs to the glycerate kinase type-1 family
HUE89_RS03705	COG3711	transcriptional antiterminator
HUE89_RS03710	COG1263	PTS System
HUE89_RS03710	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HUE89_RS03710	COG2190	(PTS) system
HUE89_RS03725	COG0531	amino acid
HUE89_RS03740	COG0217	transcriptional regulatory protein
HUE89_RS03745	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
HUE89_RS03775	COG0827	DNA restriction-modification system
HUE89_RS03800	COG1482	cell wall glycoprotein biosynthetic process
HUE89_RS03810	COG0745	RESPONSE REGULATOR receiver
HUE89_RS03815	COG5002	protein histidine kinase activity
HUE89_RS03815	COG3850	Histidine kinase
HUE89_RS03825	COG1368	sulfuric ester hydrolase activity
HUE89_RS03835	COG0166	Belongs to the GPI family
HUE89_RS03840	COG0477	Major facilitator Superfamily
HUE89_RS03845	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
HUE89_RS03905	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
HUE89_RS03910	COG1435	thymidine kinase activity
HUE89_RS03915	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
HUE89_RS03920	COG2890	protein-(glutamine-N5) methyltransferase activity
HUE89_RS03925	COG0009	L-threonylcarbamoyladenylate synthase
HUE89_RS03930	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
HUE89_RS03935	COG0356	it plays a direct role in the translocation of protons across the membrane
HUE89_RS03940	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HUE89_RS03945	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
HUE89_RS03950	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HUE89_RS03955	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
HUE89_RS03960	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
HUE89_RS03965	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
HUE89_RS03970	COG0355	proton-transporting ATP synthase activity, rotational mechanism
HUE89_RS03980	COG1077	Cell shape determining protein MreB Mrl
HUE89_RS03985	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
HUE89_RS03995	COG0772	Belongs to the SEDS family
HUE89_RS04000	COG0589	response to stress
HUE89_RS04010	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
HUE89_RS04020	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
HUE89_RS04025	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
HUE89_RS04030	COG1104	cysteine desulfurase activity
HUE89_RS04035	COG0301	tRNA thio-modification
HUE89_RS04040	COG1187	pseudouridine synthase activity
HUE89_RS04050	COG0525	valine-tRNA ligase activity
HUE89_RS04060	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HUE89_RS04065	COG2003	Belongs to the UPF0758 family
HUE89_RS04070	COG1077	Cell shape determining protein MreB Mrl
HUE89_RS04075	COG1792	Involved in formation and maintenance of cell shape
HUE89_RS04095	COG2001	Belongs to the MraZ family
HUE89_RS04100	COG0275	rRNA processing
HUE89_RS04115	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HUE89_RS04120	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
HUE89_RS04125	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HUE89_RS04130	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
HUE89_RS04140	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HUE89_RS04145	COG1799	cell septum assembly
HUE89_RS04160	COG3599	regulation of cell shape
HUE89_RS04165	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
HUE89_RS04170	COG1278	Cold shock
HUE89_RS04175	COG0494	nUDIX hydrolase
HUE89_RS04185	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HUE89_RS04195	COG0482	sulfurtransferase activity
HUE89_RS04200	COG0406	alpha-ribazole phosphatase activity
HUE89_RS04210	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
HUE89_RS04220	COG1597	lipid kinase activity
HUE89_RS04235	COG0242	peptide deformylase activity
HUE89_RS04245	COG0772	Belongs to the SEDS family
HUE89_RS04255	COG0742	ribosomal rna small subunit methyltransferase
HUE89_RS04260	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
HUE89_RS04265	COG3480	Lon protease (S16) C-terminal proteolytic domain
HUE89_RS04270	COG1596	polysaccharide export
HUE89_RS04270	COG1555	photosystem II stabilization
HUE89_RS04275	COG0658	competence protein
HUE89_RS04275	COG2333	competence protein COMEC
HUE89_RS04280	COG1466	dna polymerase III delta subunit
HUE89_RS04285	COG0268	Binds directly to 16S ribosomal RNA
HUE89_RS04290	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
HUE89_RS04305	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
HUE89_RS04310	COG0544	peptidyl-prolyl cis-trans isomerase activity
HUE89_RS04315	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
HUE89_RS04320	COG0218	Necessary for normal cell division and for the maintenance of normal septation
HUE89_RS04330	COG0527	aspartate kinase activity
HUE89_RS04335	COG0019	diaminopimelate decarboxylase activity
HUE89_RS04340	COG2171	N-acyltransferase activity
HUE89_RS04345	COG1473	amidohydrolase
HUE89_RS04350	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HUE89_RS04355	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
HUE89_RS04360	COG0436	Aminotransferase
HUE89_RS04365	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HUE89_RS04370	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
HUE89_RS04380	COG1053	succinate dehydrogenase
HUE89_RS04380	COG0431	NADPH-dependent FMN reductase
HUE89_RS04380	COG3976	FMN-binding domain protein
HUE89_RS04395	COG1957	nucleoside hydrolase
HUE89_RS04435	COG2261	transglycosylase associated protein
HUE89_RS04445	COG2723	6-phospho-beta-galactosidase activity
HUE89_RS04450	COG2188	Transcriptional regulator
HUE89_RS04455	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HUE89_RS04460	COG1447	Phosphotransferase system cellobiose-specific component IIA
HUE89_RS04480	COG2723	6-phospho-beta-galactosidase activity
HUE89_RS04485	COG2188	Transcriptional regulator
HUE89_RS04495	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HUE89_RS04500	COG2723	6-phospho-beta-galactosidase activity
HUE89_RS04520	COG0148	phosphopyruvate hydratase activity
HUE89_RS04535	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
HUE89_RS04570	COG1113	amino acid transport
HUE89_RS04575	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
HUE89_RS04585	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
HUE89_RS04595	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HUE89_RS04600	COG2011	ABC-type metal ion transport system permease component
HUE89_RS04610	COG1053	succinate dehydrogenase
HUE89_RS04620	COG0039	L-malate dehydrogenase activity
HUE89_RS04625	COG3579	cysteine-type endopeptidase activity
HUE89_RS04630	COG0471	metal ion transport
HUE89_RS04635	COG2267	carboxylic ester hydrolase activity
HUE89_RS04645	COG3052	prosthetic group binding
HUE89_RS04660	COG2707	UPF0756 membrane protein
HUE89_RS04675	COG1122	ATPase activity
HUE89_RS04680	COG4720	Psort location CytoplasmicMembrane, score
HUE89_RS04705	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HUE89_RS04710	COG2264	protein methyltransferase activity
HUE89_RS04715	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HUE89_RS04720	COG1490	D-aminoacyl-tRNA deacylase activity
HUE89_RS04725	COG0124	histidyl-tRNA synthetase
HUE89_RS04730	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
HUE89_RS04735	COG0436	Aminotransferase
HUE89_RS04740	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HUE89_RS04745	COG0656	L-ascorbic acid biosynthetic process
HUE89_RS04750	COG0561	phosphatase activity
HUE89_RS04755	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HUE89_RS04760	COG0531	amino acid
HUE89_RS04765	COG0586	Pfam SNARE associated Golgi protein
HUE89_RS04770	COG0322	excinuclease ABC activity
HUE89_RS04775	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HUE89_RS04785	COG1234	tRNA 3'-trailer cleavage
HUE89_RS04790	COG0300	oxidoreductase activity
HUE89_RS04800	COG0333	Belongs to the bacterial ribosomal protein bL32 family
HUE89_RS04805	COG0737	Belongs to the 5'-nucleotidase family
HUE89_RS04815	COG0587	DNA-directed DNA polymerase activity
HUE89_RS04820	COG0205	6-phosphofructokinase activity
HUE89_RS04830	COG2996	Protein conserved in bacteria
HUE89_RS04840	COG0456	acetyltransferase
HUE89_RS04845	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
HUE89_RS04855	COG1187	pseudouridine synthase activity
HUE89_RS04860	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
HUE89_RS04865	COG3409	Peptidoglycan-binding domain 1 protein
HUE89_RS04865	COG5632	N-Acetylmuramoyl-L-alanine amidase
HUE89_RS04870	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
HUE89_RS04875	COG0539	negative regulation of cytoplasmic translation
HUE89_RS04880	COG1160	GTP binding
HUE89_RS04895	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
HUE89_RS04900	COG0617	tRNA 3'-terminal CCA addition
HUE89_RS04905	COG1272	protein, Hemolysin III
HUE89_RS04910	COG1307	EDD domain protein, DegV family
HUE89_RS04915	COG4479	Belongs to the UPF0346 family
HUE89_RS04920	COG0025	NhaP-type Na H and K H
HUE89_RS04925	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
HUE89_RS04930	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HUE89_RS04935	COG0758	DNA mediated transformation
HUE89_RS04940	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HUE89_RS04945	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
HUE89_RS04960	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
HUE89_RS04990	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HUE89_RS04995	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HUE89_RS05005	COG0531	amino acid
HUE89_RS05015	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
HUE89_RS05020	COG0569	domain protein
HUE89_RS05025	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
HUE89_RS05030	COG0514	ATP-dependent DNA helicase (RecQ)
HUE89_RS05040	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
HUE89_RS05045	COG2040	homocysteine
HUE89_RS05085	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HUE89_RS05085	COG1263	PTS System
HUE89_RS05085	COG2190	(PTS) system
HUE89_RS05090	COG2188	Transcriptional regulator
HUE89_RS05095	COG0366	Alpha amylase catalytic
HUE89_RS05135	COG4978	Transcriptional regulator
HUE89_RS05135	COG0789	Transcriptional regulator
HUE89_RS05150	COG0583	DNA-binding transcription factor activity
HUE89_RS05155	COG0656	L-ascorbic acid biosynthetic process
HUE89_RS05160	COG0656	L-ascorbic acid biosynthetic process
HUE89_RS05165	COG0656	L-ascorbic acid biosynthetic process
HUE89_RS05175	COG0456	acetyltransferase
HUE89_RS05195	COG1959	2 iron, 2 sulfur cluster binding
HUE89_RS05200	COG1114	Component of the transport system for branched-chain amino acids
HUE89_RS05205	COG0656	L-ascorbic acid biosynthetic process
HUE89_RS05225	COG0765	amino acid transport
HUE89_RS05230	COG0765	amino acid transport
HUE89_RS05235	COG1126	abc transporter atp-binding protein
HUE89_RS05245	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
HUE89_RS05255	COG2159	amidohydrolase
HUE89_RS05280	COG2814	Major facilitator Superfamily
HUE89_RS05290	COG1051	belongs to the nudix hydrolase family
HUE89_RS05340	COG0588	phosphoglycerate mutase activity
HUE89_RS05355	COG1011	Hydrolase
HUE89_RS05395	COG0281	malic enzyme
HUE89_RS05405	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
HUE89_RS05410	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
HUE89_RS05415	COG1376	ErfK ybiS ycfS ynhG family protein
HUE89_RS05420	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
HUE89_RS05425	COG1854	S-ribosylhomocysteine lyase activity
HUE89_RS05445	COG0531	amino acid
HUE89_RS05455	COG0626	cystathionine gamma-synthase activity
HUE89_RS05460	COG0626	cystathionine gamma-synthase activity
HUE89_RS05470	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
HUE89_RS05505	COG1028	Short-chain dehydrogenase reductase Sdr
HUE89_RS05520	COG4975	Glucose uptake
HUE89_RS05540	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HUE89_RS05590	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HUE89_RS05605	COG2855	membrane
HUE89_RS05615	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
HUE89_RS05620	COG0187	DNA topoisomerase II activity
HUE89_RS05630	COG0583	DNA-binding transcription factor activity
HUE89_RS05635	COG1227	inorganic diphosphatase activity
HUE89_RS05640	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HUE89_RS05655	COG2184	nucleotidyltransferase activity
HUE89_RS05665	COG1132	(ABC) transporter
HUE89_RS05700	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
HUE89_RS05715	COG1307	EDD domain protein, DegV family
HUE89_RS05730	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
HUE89_RS05735	COG0505	Belongs to the CarA family
HUE89_RS05740	COG0564	pseudouridine synthase activity
HUE89_RS05750	COG2759	Belongs to the formate--tetrahydrofolate ligase family
HUE89_RS05760	COG0116	Belongs to the methyltransferase superfamily
HUE89_RS05770	COG3599	regulation of cell shape
HUE89_RS05775	COG4474	Belongs to the UPF0398 family
HUE89_RS05780	COG3331	DNA recombination
HUE89_RS05785	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
HUE89_RS05790	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HUE89_RS05800	COG0017	Asparaginyl-tRNA synthetase
HUE89_RS05815	COG1074	ATP-dependent DNA helicase activity
HUE89_RS05820	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
HUE89_RS05845	COG1737	Transcriptional regulator
HUE89_RS05860	COG1104	cysteine desulfurase activity
HUE89_RS05865	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
HUE89_RS05865	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
HUE89_RS05905	COG1131	(ABC) transporter
HUE89_RS05910	COG1725	Transcriptional regulator
HUE89_RS05915	COG2195	Cleaves the N-terminal amino acid of tripeptides
HUE89_RS05920	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
HUE89_RS05925	COG2384	SAM-dependent methyltransferase
HUE89_RS05930	COG2816	NAD+ diphosphatase activity
HUE89_RS05940	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HUE89_RS05945	COG0358	DNA primase activity
HUE89_RS05950	COG0751	glycine-tRNA ligase activity
HUE89_RS05955	COG0752	glycyl-tRNA synthetase alpha subunit
HUE89_RS05960	COG1381	Involved in DNA repair and RecF pathway recombination
HUE89_RS05965	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
HUE89_RS05970	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
HUE89_RS05975	COG1702	phosphate starvation-inducible protein PhoH
HUE89_RS05985	COG0828	Belongs to the bacterial ribosomal protein bS21 family
HUE89_RS05990	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
HUE89_RS06000	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HUE89_RS06005	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
HUE89_RS06015	COG0083	homoserine kinase activity
HUE89_RS06030	COG0527	aspartate kinase activity
HUE89_RS06035	COG4166	transmembrane transport
HUE89_RS06045	COG0110	maltose O-acetyltransferase activity
HUE89_RS06065	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HUE89_RS06070	COG1114	Component of the transport system for branched-chain amino acids
HUE89_RS06110	COG0583	DNA-binding transcription factor activity
HUE89_RS06115	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
HUE89_RS06135	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
HUE89_RS06145	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
HUE89_RS06155	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HUE89_RS06160	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
HUE89_RS06160	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
HUE89_RS06165	COG3764	Sortase (surface protein transpeptidase)
HUE89_RS06170	COG0481	GTPase activity
HUE89_RS06175	COG0484	heat shock protein binding
HUE89_RS06180	COG0443	Heat shock 70 kDa protein
HUE89_RS06185	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HUE89_RS06190	COG1420	regulation of RNA biosynthetic process
HUE89_RS06195	COG0488	(ABC) transporter
HUE89_RS06200	COG0196	riboflavin kinase activity
HUE89_RS06205	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
HUE89_RS06210	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
HUE89_RS06215	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
HUE89_RS06225	COG2740	Nucleic-acid-binding protein implicated in transcription termination
HUE89_RS06230	COG0195	Participates in both transcription termination and antitermination
HUE89_RS06235	COG0779	Required for maturation of 30S ribosomal subunits
HUE89_RS06245	COG0442	prolyl-tRNA aminoacylation
HUE89_RS06250	COG0750	zinc metalloprotease
HUE89_RS06255	COG4589	Belongs to the CDS family
HUE89_RS06260	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HUE89_RS06265	COG0233	cytoplasmic translational termination
HUE89_RS06270	COG0528	UMP kinase activity
HUE89_RS06275	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
HUE89_RS06280	COG0052	Belongs to the universal ribosomal protein uS2 family
HUE89_RS06285	COG2827	Endonuclease containing a URI domain
HUE89_RS06290	COG0204	Acyl-transferase
HUE89_RS06295	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
HUE89_RS06300	COG3590	peptidase
HUE89_RS06305	COG1132	(ABC) transporter
HUE89_RS06310	COG1132	(ABC) transporter
HUE89_RS06315	COG3763	UPF0154 protein
HUE89_RS06320	COG4224	UPF0291 protein
HUE89_RS06325	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HUE89_RS06340	COG0463	Glycosyl transferase, family 2
HUE89_RS06355	COG0335	large ribosomal subunit rRNA binding
HUE89_RS06360	COG0336	Belongs to the RNA methyltransferase TrmD family
HUE89_RS06365	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
HUE89_RS06370	COG0228	four-way junction DNA binding
HUE89_RS06375	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HUE89_RS06380	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
HUE89_RS06385	COG0531	amino acid
HUE89_RS06400	COG0552	protein localization to endoplasmic reticulum
HUE89_RS06405	COG1196	nuclear chromosome segregation
HUE89_RS06410	COG0571	ribonuclease III activity
HUE89_RS06415	COG2801	Transposase and inactivated derivatives
HUE89_RS06435	COG0601	transmembrane transport
HUE89_RS06440	COG4608	Belongs to the ABC transporter superfamily
HUE89_RS06450	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HUE89_RS06455	COG0416	fatty acid biosynthetic process
HUE89_RS06460	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HUE89_RS06475	COG0227	Belongs to the bacterial ribosomal protein bL28 family
HUE89_RS06490	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
HUE89_RS06495	COG1162	GTPase activity
HUE89_RS06500	COG0515	serine threonine protein kinase
HUE89_RS06500	COG2815	serine threonine protein kinase
HUE89_RS06505	COG0631	protein serine/threonine phosphatase activity
HUE89_RS06510	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HUE89_RS06510	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
HUE89_RS06515	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HUE89_RS06520	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HUE89_RS06525	COG1758	RNA polymerase activity
HUE89_RS06530	COG0194	GDP metabolic process
HUE89_RS06540	COG0497	DNA recombination
HUE89_RS06545	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
HUE89_RS06555	COG1722	exodeoxyribonuclease VII activity
HUE89_RS06560	COG1570	exodeoxyribonuclease VII activity
HUE89_RS06565	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
HUE89_RS06575	COG1302	Protein conserved in bacteria
HUE89_RS06580	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HUE89_RS06585	COG0006	proline dipeptidase activity
HUE89_RS06590	COG0211	Belongs to the bacterial ribosomal protein bL27 family
HUE89_RS06595	COG0261	This protein binds to 23S rRNA in the presence of protein L20
HUE89_RS06600	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
HUE89_RS06610	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
HUE89_RS06615	COG1942	4-Oxalocrotonate Tautomerase
HUE89_RS06630	COG3231	kanamycin kinase activity
HUE89_RS06665	COG1393	Belongs to the ArsC family
HUE89_RS06675	COG1136	(ABC) transporter
HUE89_RS06680	COG0561	phosphatase activity
HUE89_RS06690	COG1874	Beta-galactosidase
HUE89_RS06695	COG1501	Belongs to the glycosyl hydrolase 31 family
HUE89_RS06700	COG2723	6-phospho-beta-galactosidase activity
HUE89_RS06705	COG1940	carbohydrate kinase activity
HUE89_RS06710	COG1940	carbohydrate kinase activity
HUE89_RS06710	COG1846	Transcriptional regulator
HUE89_RS06715	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HUE89_RS06735	COG2936	dipeptidyl-peptidase activity
HUE89_RS06740	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HUE89_RS06750	COG4975	Glucose uptake
HUE89_RS06765	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
HUE89_RS06770	COG0505	Belongs to the CarA family
HUE89_RS06775	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
HUE89_RS06780	COG0540	Belongs to the ATCase OTCase family
HUE89_RS06790	COG0167	dihydroorotate dehydrogenase activity
HUE89_RS06795	COG0284	orotidine-5'-phosphate decarboxylase activity
HUE89_RS06800	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HUE89_RS06810	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
HUE89_RS06815	COG0038	chloride channel
HUE89_RS06840	COG1464	Belongs to the NlpA lipoprotein family
HUE89_RS06850	COG1760	l-serine dehydratase
HUE89_RS06855	COG1760	l-serine dehydratase
HUE89_RS06860	COG2151	metal-sulfur cluster biosynthetic enzyme
HUE89_RS06865	COG0747	negative chemotaxis
HUE89_RS06870	COG0446	pyridine nucleotide-disulphide oxidoreductase
HUE89_RS06885	COG0702	epimerase
HUE89_RS06890	COG2337	Toxic component of a toxin-antitoxin (TA) module
HUE89_RS06915	COG0431	NADPH-dependent FMN reductase
HUE89_RS06915	COG1053	succinate dehydrogenase
HUE89_RS06915	COG3976	FMN-binding domain protein
HUE89_RS06925	COG3706	GGDEF domain
HUE89_RS06950	COG1902	pentaerythritol trinitrate reductase activity
HUE89_RS06970	COG1335	isochorismatase
HUE89_RS07010	COG5002	protein histidine kinase activity
HUE89_RS07015	COG0745	RESPONSE REGULATOR receiver
HUE89_RS07020	COG2357	RelA SpoT domain protein
HUE89_RS07025	COG2376	Dihydroxyacetone kinase
HUE89_RS07030	COG1461	Dihydroxyacetone kinase
HUE89_RS07035	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
HUE89_RS07040	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
HUE89_RS07045	COG0366	Alpha amylase catalytic
HUE89_RS07050	COG3345	alpha-galactosidase
HUE89_RS07055	COG3842	ATPase activity
HUE89_RS07060	COG0395	ABC-type sugar transport system, permease component
HUE89_RS07065	COG1175	transmembrane transport
HUE89_RS07070	COG1653	transport
HUE89_RS07085	COG2814	Major facilitator Superfamily
HUE89_RS07125	COG2017	converts alpha-aldose to the beta-anomer
HUE89_RS07130	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
HUE89_RS07135	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
HUE89_RS07150	COG1874	Beta-galactosidase
HUE89_RS07155	COG2211	Major facilitator Superfamily
HUE89_RS07155	COG2190	(PTS) system
HUE89_RS07165	COG1609	Transcriptional regulator
HUE89_RS07170	COG3250	beta-galactosidase activity
HUE89_RS07175	COG3250	beta-galactosidase activity
HUE89_RS07180	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
HUE89_RS07195	COG1609	Transcriptional regulator
HUE89_RS07200	COG3250	beta-galactosidase activity
HUE89_RS07210	COG2801	Transposase and inactivated derivatives
HUE89_RS07225	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HUE89_RS07225	COG1263	PTS System
HUE89_RS07225	COG2190	(PTS) system
HUE89_RS07230	COG3711	transcriptional antiterminator
HUE89_RS07240	COG1879	ABC-type sugar transport system periplasmic component
HUE89_RS07255	COG1869	D-ribose catabolic process
HUE89_RS07275	COG1609	Transcriptional regulator
HUE89_RS07280	COG3959	Transketolase, thiamine diphosphate binding domain
HUE89_RS07285	COG3958	Transketolase
HUE89_RS07290	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HUE89_RS07300	COG0477	Major facilitator Superfamily
HUE89_RS07310	COG4932	domain protein
HUE89_RS07310	COG2373	Large extracellular alpha-helical protein
HUE89_RS07310	COG1388	LysM domain
HUE89_RS07325	COG4619	ABC transporter
HUE89_RS07330	COG0390	transport system, permease component
HUE89_RS07345	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
HUE89_RS07350	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HUE89_RS07365	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HUE89_RS07370	COG0267	Belongs to the bacterial ribosomal protein bL33 family
HUE89_RS07375	COG0768	penicillin binding
HUE89_RS07385	COG2971	BadF BadG BcrA BcrD
HUE89_RS07405	COG2195	Cleaves the N-terminal amino acid of tripeptides
HUE89_RS07420	COG0072	phenylalanine-tRNA ligase activity
HUE89_RS07425	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
HUE89_RS07430	COG1733	regulation of RNA biosynthetic process
HUE89_RS07435	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HUE89_RS07440	COG1254	Belongs to the acylphosphatase family
HUE89_RS07445	COG0706	membrane insertase activity
HUE89_RS07450	COG5002	protein histidine kinase activity
HUE89_RS07455	COG0745	RESPONSE REGULATOR receiver
HUE89_RS07465	COG1323	Belongs to the UPF0348 family
HUE89_RS07470	COG0799	negative regulation of ribosome biogenesis
HUE89_RS07475	COG1713	HD superfamily hydrolase involved in NAD metabolism
HUE89_RS07480	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
HUE89_RS07485	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
HUE89_RS07490	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
HUE89_RS07500	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
HUE89_RS07505	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
HUE89_RS07510	COG0291	Belongs to the bacterial ribosomal protein bL35 family
HUE89_RS07515	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
HUE89_RS07535	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HUE89_RS07540	COG1484	DNA-dependent DNA replication
HUE89_RS07550	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HUE89_RS07555	COG0237	dephospho-CoA kinase activity
HUE89_RS07560	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
HUE89_RS07565	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HUE89_RS07565	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HUE89_RS07570	COG0151	Belongs to the GarS family
HUE89_RS07575	COG0138	bifunctional purine biosynthesis protein purh
HUE89_RS07580	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
HUE89_RS07585	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
HUE89_RS07595	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HUE89_RS07600	COG0047	phosphoribosylformylglycinamidine synthase activity
HUE89_RS07605	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HUE89_RS07610	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
HUE89_RS07615	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
HUE89_RS07620	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
HUE89_RS07625	COG2759	Belongs to the formate--tetrahydrofolate ligase family
HUE89_RS07685	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HUE89_RS07685	COG2190	(PTS) system
HUE89_RS07685	COG1263	PTS System
HUE89_RS07690	COG2190	(PTS) system
HUE89_RS07690	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HUE89_RS07690	COG1263	PTS System
HUE89_RS07705	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
HUE89_RS07710	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HUE89_RS07715	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
HUE89_RS07720	COG0220	tRNA (guanine-N7-)-methyltransferase activity
HUE89_RS07730	COG1131	(ABC) transporter
HUE89_RS07735	COG0537	adenosine 5'-monophosphoramidase activity
HUE89_RS07745	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
HUE89_RS07750	COG3481	metal-dependent phosphohydrolase, HD sub domain
HUE89_RS07765	COG3679	Belongs to the UPF0342 family
HUE89_RS07770	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
HUE89_RS07775	COG0564	pseudouridine synthase activity
HUE89_RS07780	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
HUE89_RS07800	COG0018	arginyl-trna synthetase
HUE89_RS07805	COG1376	ErfK ybiS ycfS ynhG family protein
HUE89_RS07810	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
HUE89_RS07815	COG1686	Belongs to the peptidase S11 family
HUE89_RS07880	COG2244	polysaccharide biosynthetic process
HUE89_RS07885	COG0495	leucyl-tRNA aminoacylation
HUE89_RS07890	COG0671	phosphoesterase, PA-phosphatase related
HUE89_RS07905	COG0477	Major facilitator Superfamily
HUE89_RS07910	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
HUE89_RS07955	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HUE89_RS07965	COG0398	Pfam SNARE associated Golgi protein
HUE89_RS07985	COG1012	belongs to the aldehyde dehydrogenase family
HUE89_RS08005	COG1033	growth of symbiont in host cell
HUE89_RS08005	COG2409	Drug exporters of the RND superfamily
HUE89_RS08040	COG1175	transmembrane transport
HUE89_RS08060	COG2176	DNA-directed DNA polymerase activity
HUE89_RS08105	COG1132	(ABC) transporter
HUE89_RS08110	COG2267	carboxylic ester hydrolase activity
HUE89_RS08115	COG0745	RESPONSE REGULATOR receiver
HUE89_RS08120	COG5002	protein histidine kinase activity
HUE89_RS08135	COG1846	Transcriptional regulator
HUE89_RS08145	COG4166	transmembrane transport
HUE89_RS08160	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HUE89_RS08180	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HUE89_RS08185	COG1126	abc transporter atp-binding protein
HUE89_RS08190	COG0765	amino acid transport
HUE89_RS08205	COG0588	phosphoglycerate mutase activity
HUE89_RS08215	COG1136	(ABC) transporter
HUE89_RS08250	COG0252	asparaginase activity
HUE89_RS08300	COG0708	Exodeoxyribonuclease III
HUE89_RS08305	COG2207	Transcriptional regulator
HUE89_RS08315	COG1737	Transcriptional regulator
HUE89_RS08325	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
HUE89_RS08330	COG1263	PTS System
HUE89_RS08330	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HUE89_RS08335	COG2723	6-phospho-beta-galactosidase activity
HUE89_RS08340	COG1263	PTS System
HUE89_RS08340	COG2190	(PTS) system
HUE89_RS08340	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HUE89_RS08345	COG3711	transcriptional antiterminator
HUE89_RS08355	COG1523	belongs to the glycosyl hydrolase 13 family
HUE89_RS08415	COG1210	Utp--glucose-1-phosphate uridylyltransferase
HUE89_RS08420	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
HUE89_RS08435	COG2244	polysaccharide biosynthetic process
HUE89_RS08475	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
HUE89_RS08480	COG4464	protein tyrosine phosphatase activity
HUE89_RS08485	COG0489	protein tyrosine kinase activity
HUE89_RS08495	COG1316	TRANSCRIPTIONal
HUE89_RS08500	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HUE89_RS08515	COG0791	NLP P60 protein
HUE89_RS08520	COG0791	NLP P60 protein
HUE89_RS08525	COG0791	NLP P60 protein
HUE89_RS08550	COG1780	Probably involved in ribonucleotide reductase function
HUE89_RS08565	COG4990	cell redox homeostasis
HUE89_RS08570	COG2151	metal-sulfur cluster biosynthetic enzyme
HUE89_RS08595	COG0488	(ABC) transporter
HUE89_RS08610	COG1316	TRANSCRIPTIONal
HUE89_RS08615	COG1164	Oligoendopeptidase f
HUE89_RS08630	COG1620	l-lactate permease
HUE89_RS08640	COG1108	ABC-type Mn2 Zn2 transport systems permease components
HUE89_RS08645	COG1121	(ABC) transporter
HUE89_RS08655	COG0640	Transcriptional regulator
HUE89_RS08670	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HUE89_RS08670	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HUE89_RS08670	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HUE89_RS08675	COG1105	Belongs to the carbohydrate kinase PfkB family
HUE89_RS08680	COG1349	DNA-binding transcription factor activity
HUE89_RS08690	COG1668	transmembrane transport
HUE89_RS08695	COG4152	abc transporter atp-binding protein
HUE89_RS08715	COG3655	Transcriptional regulator
HUE89_RS08755	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HUE89_RS08760	COG2274	protein secretion by the type I secretion system
HUE89_RS08850	COG1794	racemase activity, acting on amino acids and derivatives
HUE89_RS08855	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HUE89_RS08870	COG1132	(ABC) transporter
HUE89_RS08875	COG1132	(ABC) transporter
HUE89_RS08885	COG0012	GTP binding
HUE89_RS08890	COG4481	Protein conserved in bacteria
HUE89_RS08895	COG1475	DNA binding
HUE89_RS08900	COG1192	Involved in chromosome partitioning
HUE89_RS08910	COG0357	Ribosomal RNA small subunit methyltransferase G
HUE89_RS08930	COG0431	NADPH-dependent FMN reductase
HUE89_RS08935	COG0431	NADPH-dependent FMN reductase
HUE89_RS08955	COG1136	(ABC) transporter
HUE89_RS08980	COG3022	response to hydroperoxide
HUE89_RS08990	COG3104	oligopeptide transport
HUE89_RS09005	COG3104	oligopeptide transport
HUE89_RS09010	COG0308	aminopeptidase N
HUE89_RS09040	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
HUE89_RS09065	COG3833	ABC-type maltose transport systems, permease component
HUE89_RS09070	COG1175	transmembrane transport
HUE89_RS09080	COG3842	ATPase activity
HUE89_RS09085	COG2801	Transposase and inactivated derivatives
HUE89_RS09090	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HUE89_RS09105	COG0366	Alpha amylase catalytic
HUE89_RS09110	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HUE89_RS09115	COG1609	Transcriptional regulator
HUE89_RS09120	COG2365	Tyrosine phosphatase family
HUE89_RS09125	COG1132	(ABC) transporter
HUE89_RS09140	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HUE89_RS09145	COG0351	phosphomethylpyrimidine kinase
HUE89_RS09160	COG3442	glutamine amidotransferase
HUE89_RS09165	COG0791	NLP P60 protein
HUE89_RS09180	COG0697	spore germination
HUE89_RS09195	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HUE89_RS09200	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
HUE89_RS09205	COG0516	GMP reductase activity
HUE89_RS09225	COG2502	aspartate--ammonia ligase
HUE89_RS09235	COG0492	ferredoxin-NADP+ reductase activity
HUE89_RS09240	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HUE89_RS09260	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
HUE89_RS09265	COG1113	amino acid transport
HUE89_RS09270	COG1113	amino acid transport
HUE89_RS09290	COG0542	response to heat
HUE89_RS09305	COG1136	(ABC) transporter
HUE89_RS09305	COG0577	efflux transmembrane transporter activity
HUE89_RS09320	COG2244	polysaccharide biosynthetic process
HUE89_RS09350	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
HUE89_RS09355	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HUE89_RS09360	COG1696	Membrane protein involved in D-alanine export
HUE89_RS09365	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HUE89_RS09380	COG0516	GMP reductase activity
HUE89_RS09380	COG0517	IMP dehydrogenase activity
HUE89_RS09385	COG2217	Heavy metal translocating P-type atpase
HUE89_RS09400	COG1132	(ABC) transporter
HUE89_RS09415	COG1396	sequence-specific DNA binding
HUE89_RS09430	COG1136	(ABC) transporter
HUE89_RS09430	COG0577	efflux transmembrane transporter activity
HUE89_RS09430	COG1136	(ABC) transporter
HUE89_RS09430	COG0577	efflux transmembrane transporter activity
HUE89_RS09440	COG1744	ABC transporter substrate-binding protein PnrA-like
HUE89_RS09445	COG1744	ABC transporter substrate-binding protein PnrA-like
HUE89_RS09465	COG0656	L-ascorbic acid biosynthetic process
HUE89_RS09470	COG0363	glucosamine-6-phosphate deaminase activity
HUE89_RS09475	COG1428	Deoxynucleoside kinase
HUE89_RS09480	COG1428	Deoxynucleoside kinase
HUE89_RS09485	COG0561	phosphatase activity
HUE89_RS09490	COG2252	PERMEase
HUE89_RS09495	COG2801	Transposase and inactivated derivatives
HUE89_RS09505	COG2252	PERMEase
HUE89_RS09510	COG2267	carboxylic ester hydrolase activity
HUE89_RS09515	COG4166	transmembrane transport
HUE89_RS09520	COG2252	PERMEase
HUE89_RS09530	COG4166	transmembrane transport
HUE89_RS09550	COG2217	Heavy metal translocating P-type atpase
HUE89_RS09565	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HUE89_RS09585	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
HUE89_RS09590	COG0028	Belongs to the TPP enzyme family
HUE89_RS09595	COG0445	tRNA wobble uridine modification
HUE89_RS09600	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
HUE89_RS09605	COG0706	membrane insertase activity
HUE89_RS09610	COG0594	ribonuclease P activity
HUE89_RS09615	COG0230	Belongs to the bacterial ribosomal protein bL34 family