locus-tag	class	description
CXB72_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
CXB72_RS00015	COG2501	S4 domain
CXB72_RS00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
CXB72_RS00025	COG0187	DNA topoisomerase II activity
CXB72_RS00030	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CXB72_RS00035	COG0360	Binds together with S18 to 16S ribosomal RNA
CXB72_RS00040	COG0629	single-stranded DNA binding
CXB72_RS00045	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
CXB72_RS00055	COG0359	binds to the 23S rRNA
CXB72_RS00060	COG0305	Participates in initiation and elongation during chromosome replication
CXB72_RS00075	COG1940	carbohydrate kinase activity
CXB72_RS00080	COG3237	CsbD-like
CXB72_RS00085	COG2261	transglycosylase associated protein
CXB72_RS00135	COG1131	(ABC) transporter
CXB72_RS00215	COG2096	Adenosyltransferase
CXB72_RS00230	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CXB72_RS00235	COG0628	permease
CXB72_RS00260	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CXB72_RS00275	COG1011	Hydrolase
CXB72_RS00285	COG0561	phosphatase activity
CXB72_RS00305	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CXB72_RS00310	COG0708	Exodeoxyribonuclease III
CXB72_RS00315	COG0531	amino acid
CXB72_RS00320	COG0513	Belongs to the DEAD box helicase family
CXB72_RS00395	COG1053	succinate dehydrogenase
CXB72_RS00395	COG3976	FMN-binding domain protein
CXB72_RS00400	COG1053	succinate dehydrogenase
CXB72_RS00400	COG3976	FMN-binding domain protein
CXB72_RS00405	COG3976	FMN-binding domain protein
CXB72_RS00405	COG1053	succinate dehydrogenase
CXB72_RS00435	COG1442	glycosyl transferase family 8
CXB72_RS00490	COG1132	(ABC) transporter
CXB72_RS00510	COG0745	RESPONSE REGULATOR receiver
CXB72_RS00515	COG5002	protein histidine kinase activity
CXB72_RS00530	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
CXB72_RS00535	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CXB72_RS00540	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
CXB72_RS00575	COG2267	carboxylic ester hydrolase activity
CXB72_RS00585	COG1122	ATPase activity
CXB72_RS00595	COG0501	Belongs to the peptidase M48B family
CXB72_RS00600	COG1704	LemA family
CXB72_RS00605	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
CXB72_RS00640	COG1215	transferase activity, transferring glycosyl groups
CXB72_RS00665	COG1126	abc transporter atp-binding protein
CXB72_RS00670	COG0765	amino acid transport
CXB72_RS00675	COG2094	Belongs to the DNA glycosylase MPG family
CXB72_RS00680	COG3189	MarR family transcriptional regulator
CXB72_RS00685	COG0861	Integral membrane protein TerC family
CXB72_RS00695	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
CXB72_RS00705	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CXB72_RS00715	COG0328	RNA-DNA hybrid ribonuclease activity
CXB72_RS00725	COG1216	Glycosyl transferase, family 2
CXB72_RS00770	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CXB72_RS00785	COG0765	amino acid transport
CXB72_RS00790	COG1126	abc transporter atp-binding protein
CXB72_RS00800	COG1181	Belongs to the D-alanine--D-alanine ligase family
CXB72_RS00850	COG2365	Tyrosine phosphatase family
CXB72_RS00860	COG0589	response to stress
CXB72_RS00875	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
CXB72_RS00885	COG3639	organic phosphonate transmembrane transporter activity
CXB72_RS00890	COG0519	Catalyzes the synthesis of GMP from XMP
CXB72_RS00905	COG0367	asparagine synthase
CXB72_RS00920	COG0602	queuosine metabolic process
CXB72_RS00925	COG2151	metal-sulfur cluster biosynthetic enzyme
CXB72_RS00935	COG2814	Major facilitator Superfamily
CXB72_RS00940	COG3590	peptidase
CXB72_RS00945	COG3158	transport of potassium into the cell
CXB72_RS00985	COG1705	Flagellar rod assembly protein muramidase FlgJ
CXB72_RS00985	COG1388	LysM domain
CXB72_RS00995	COG0475	glutathione-regulated potassium exporter activity
CXB72_RS00995	COG0569	domain protein
CXB72_RS01000	COG0673	inositol 2-dehydrogenase activity
CXB72_RS01015	COG0588	phosphoglycerate mutase activity
CXB72_RS01020	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
CXB72_RS01030	COG1316	TRANSCRIPTIONal
CXB72_RS01035	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
CXB72_RS01040	COG1368	sulfuric ester hydrolase activity
CXB72_RS01050	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CXB72_RS01065	COG3579	cysteine-type endopeptidase activity
CXB72_RS01070	COG1418	mRNA catabolic process
CXB72_RS01075	COG4166	transmembrane transport
CXB72_RS01080	COG4166	transmembrane transport
CXB72_RS01085	COG0516	GMP reductase activity
CXB72_RS01085	COG0517	IMP dehydrogenase activity
CXB72_RS01090	COG0601	transmembrane transport
CXB72_RS01095	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CXB72_RS01100	COG0444	Belongs to the ABC transporter superfamily
CXB72_RS01105	COG4608	Belongs to the ABC transporter superfamily
CXB72_RS01110	COG3579	cysteine-type endopeptidase activity
CXB72_RS01120	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CXB72_RS01145	COG2131	deaminase
CXB72_RS01155	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
CXB72_RS01160	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CXB72_RS01160	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CXB72_RS01165	COG0084	hydrolase, TatD family'
CXB72_RS01175	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
CXB72_RS01180	COG4466	Protein conserved in bacteria
CXB72_RS01185	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CXB72_RS01190	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
CXB72_RS01210	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CXB72_RS01215	COG2723	6-phospho-beta-galactosidase activity
CXB72_RS01220	COG1737	Transcriptional regulator
CXB72_RS01225	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CXB72_RS01240	COG1078	dGTPase activity
CXB72_RS01255	COG0504	CTP synthase activity
CXB72_RS01260	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CXB72_RS01265	COG4690	dipeptidase activity
CXB72_RS01285	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CXB72_RS01295	COG1396	sequence-specific DNA binding
CXB72_RS01300	COG0519	Catalyzes the synthesis of GMP from XMP
CXB72_RS01305	COG0148	phosphopyruvate hydratase activity
CXB72_RS01315	COG1511	domain protein
CXB72_RS01320	COG2910	NAD(P)H-binding
CXB72_RS01325	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
CXB72_RS01400	COG2814	Major facilitator Superfamily
CXB72_RS01420	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CXB72_RS01450	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
CXB72_RS01455	COG0531	amino acid
CXB72_RS01460	COG0561	phosphatase activity
CXB72_RS01465	COG0366	Alpha amylase catalytic
CXB72_RS01470	COG0254	rRNA binding
CXB72_RS01475	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
CXB72_RS01485	COG0736	holo-[acyl-carrier-protein] synthase activity
CXB72_RS01490	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CXB72_RS01500	COG0039	L-malate dehydrogenase activity
CXB72_RS01505	COG0193	aminoacyl-tRNA hydrolase activity
CXB72_RS01510	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CXB72_RS01515	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
CXB72_RS01530	COG0037	tRNA processing
CXB72_RS01540	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
CXB72_RS01545	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CXB72_RS01550	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
CXB72_RS01570	COG1956	GAF domain-containing protein
CXB72_RS01575	COG0542	response to heat
CXB72_RS01580	COG0085	RNA polymerase activity
CXB72_RS01585	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CXB72_RS01595	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
CXB72_RS01600	COG0049	tRNA binding
CXB72_RS01605	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CXB72_RS01610	COG0051	transcription antitermination factor activity, RNA binding
CXB72_RS01615	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
CXB72_RS01620	COG0088	Forms part of the polypeptide exit tunnel
CXB72_RS01625	COG0089	rRNA binding
CXB72_RS01630	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
CXB72_RS01640	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
CXB72_RS01645	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
CXB72_RS01650	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
CXB72_RS01655	COG0255	Belongs to the universal ribosomal protein uL29 family
CXB72_RS01660	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
CXB72_RS01665	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
CXB72_RS01670	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
CXB72_RS01675	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
CXB72_RS01685	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
CXB72_RS01690	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
CXB72_RS01695	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
CXB72_RS01700	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
CXB72_RS01705	COG1841	ribosomal large subunit assembly
CXB72_RS01710	COG0200	Binds to the 23S rRNA
CXB72_RS01720	COG0563	adenylate kinase activity
CXB72_RS01725	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
CXB72_RS01735	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
CXB72_RS01740	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
CXB72_RS01745	COG0202	RNA polymerase activity
CXB72_RS01750	COG0203	ribosomal protein L17
CXB72_RS01755	COG1122	ATPase activity
CXB72_RS01760	COG1122	ATPase activity
CXB72_RS01765	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
CXB72_RS01770	COG0101	tRNA pseudouridine synthase activity
CXB72_RS01775	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
CXB72_RS01800	COG1011	Hydrolase
CXB72_RS01815	COG1230	cation diffusion facilitator family transporter
CXB72_RS01825	COG0588	phosphoglycerate mutase activity
CXB72_RS01845	COG0756	dUTP diphosphatase activity
CXB72_RS01855	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CXB72_RS01860	COG0215	cysteine-tRNA ligase activity
CXB72_RS01865	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
CXB72_RS01870	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CXB72_RS01890	COG1070	Carbohydrate kinase
CXB72_RS01900	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
CXB72_RS01905	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CXB72_RS01915	COG0250	Participates in transcription elongation, termination and antitermination
CXB72_RS01920	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
CXB72_RS01925	COG0081	regulation of translation
CXB72_RS01935	COG0573	inorganic phosphate transmembrane transporter activity
CXB72_RS01940	COG0581	inorganic phosphate transmembrane transporter activity
CXB72_RS01945	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CXB72_RS01950	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CXB72_RS01955	COG0704	Plays a role in the regulation of phosphate uptake
CXB72_RS01960	COG0679	Auxin Efflux Carrier
CXB72_RS01970	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
CXB72_RS01975	COG0222	ribosome binding
CXB72_RS01985	COG2813	Specifically methylates the guanine in position
CXB72_RS01995	COG0590	tRNA wobble adenosine to inosine editing
CXB72_RS02005	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CXB72_RS02015	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
CXB72_RS02020	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
CXB72_RS02030	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
CXB72_RS02035	COG3870	Protein conserved in bacteria
CXB72_RS02040	COG0470	DNA polymerase III
CXB72_RS02060	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
CXB72_RS02065	COG1214	PFAM Peptidase M22, glycoprotease
CXB72_RS02070	COG0456	acetyltransferase
CXB72_RS02075	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
CXB72_RS02080	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
CXB72_RS02090	COG2188	Transcriptional regulator
CXB72_RS02110	COG0488	(ABC) transporter
CXB72_RS02115	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
CXB72_RS02125	COG1621	beta-fructofuranosidase activity
CXB72_RS02130	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CXB72_RS02130	COG2190	(PTS) system
CXB72_RS02130	COG1263	PTS System
CXB72_RS02150	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
CXB72_RS02155	COG0459	protein refolding
CXB72_RS02165	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
CXB72_RS02170	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
CXB72_RS02175	COG0632	four-way junction helicase activity
CXB72_RS02180	COG2255	four-way junction helicase activity
CXB72_RS02190	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
CXB72_RS02195	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CXB72_RS02200	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
CXB72_RS02205	COG0513	Belongs to the DEAD box helicase family
CXB72_RS02210	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CXB72_RS02215	COG4472	Bacterial protein of unknown function (DUF965)
CXB72_RS02220	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
CXB72_RS02225	COG3906	Belongs to the UPF0473 family
CXB72_RS02230	COG1193	negative regulation of DNA recombination
CXB72_RS02235	COG3118	belongs to the thioredoxin family
CXB72_RS02245	COG1970	mechanosensitive ion channel activity
CXB72_RS02255	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
CXB72_RS02260	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
CXB72_RS02265	COG0668	transmembrane transport
CXB72_RS02280	COG0006	proline dipeptidase activity
CXB72_RS02290	COG0584	glycerophosphoryl diester phosphodiesterase
CXB72_RS02300	COG0737	Belongs to the 5'-nucleotidase family
CXB72_RS02310	COG0647	UMP catabolic process
CXB72_RS02320	COG0586	Pfam SNARE associated Golgi protein
CXB72_RS02325	COG0492	ferredoxin-NADP+ reductase activity
CXB72_RS02435	COG0494	nUDIX hydrolase
CXB72_RS02500	COG0438	transferase activity, transferring glycosyl groups
CXB72_RS02505	COG0438	transferase activity, transferring glycosyl groups
CXB72_RS02515	COG1368	sulfuric ester hydrolase activity
CXB72_RS02525	COG0557	exoribonuclease II activity
CXB72_RS02530	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
CXB72_RS02580	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
CXB72_RS02585	COG0477	Major facilitator Superfamily
CXB72_RS02605	COG0671	phosphoesterase, PA-phosphatase related
CXB72_RS02610	COG0495	leucyl-tRNA aminoacylation
CXB72_RS02615	COG2244	polysaccharide biosynthetic process
CXB72_RS02675	COG1686	Belongs to the peptidase S11 family
CXB72_RS02680	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
CXB72_RS02685	COG1376	ErfK ybiS ycfS ynhG family protein
CXB72_RS02690	COG0018	arginyl-trna synthetase
CXB72_RS02710	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
CXB72_RS02715	COG0564	pseudouridine synthase activity
CXB72_RS02720	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CXB72_RS02725	COG3679	Belongs to the UPF0342 family
CXB72_RS02740	COG3481	metal-dependent phosphohydrolase, HD sub domain
CXB72_RS02745	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CXB72_RS02755	COG0537	adenosine 5'-monophosphoramidase activity
CXB72_RS02760	COG1131	(ABC) transporter
CXB72_RS02770	COG0220	tRNA (guanine-N7-)-methyltransferase activity
CXB72_RS02775	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CXB72_RS02780	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CXB72_RS02785	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CXB72_RS02800	COG1263	PTS System
CXB72_RS02800	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CXB72_RS02800	COG2190	(PTS) system
CXB72_RS02860	COG2759	Belongs to the formate--tetrahydrofolate ligase family
CXB72_RS02865	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
CXB72_RS02870	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
CXB72_RS02875	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
CXB72_RS02880	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CXB72_RS02885	COG0047	phosphoribosylformylglycinamidine synthase activity
CXB72_RS02890	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CXB72_RS02900	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
CXB72_RS02905	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
CXB72_RS02910	COG0138	bifunctional purine biosynthesis protein purh
CXB72_RS02915	COG0151	Belongs to the GarS family
CXB72_RS02935	COG1857	crispr-associated protein
CXB72_RS02950	COG1518	maintenance of DNA repeat elements
CXB72_RS02960	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CXB72_RS02960	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CXB72_RS02965	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
CXB72_RS02970	COG0237	dephospho-CoA kinase activity
CXB72_RS02975	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
CXB72_RS02985	COG1484	DNA-dependent DNA replication
CXB72_RS02990	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
CXB72_RS03010	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
CXB72_RS03015	COG0291	Belongs to the bacterial ribosomal protein bL35 family
CXB72_RS03020	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
CXB72_RS03025	COG2207	Transcriptional regulator
CXB72_RS03025	COG0662	Cupin 2, conserved barrel domain protein
CXB72_RS03030	COG1621	beta-fructofuranosidase activity
CXB72_RS03035	COG1263	PTS System
CXB72_RS03035	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CXB72_RS03035	COG2190	(PTS) system
CXB72_RS03040	COG3345	alpha-galactosidase
CXB72_RS03045	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
CXB72_RS03050	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
CXB72_RS03055	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
CXB72_RS03060	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
CXB72_RS03065	COG1713	HD superfamily hydrolase involved in NAD metabolism
CXB72_RS03070	COG0799	negative regulation of ribosome biogenesis
CXB72_RS03075	COG1323	Belongs to the UPF0348 family
CXB72_RS03085	COG0745	RESPONSE REGULATOR receiver
CXB72_RS03090	COG5002	protein histidine kinase activity
CXB72_RS03095	COG0706	membrane insertase activity
CXB72_RS03100	COG1254	Belongs to the acylphosphatase family
CXB72_RS03105	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CXB72_RS03110	COG1733	regulation of RNA biosynthetic process
CXB72_RS03115	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
CXB72_RS03120	COG0072	phenylalanine-tRNA ligase activity
CXB72_RS03135	COG2195	Cleaves the N-terminal amino acid of tripeptides
CXB72_RS03155	COG2971	BadF BadG BcrA BcrD
CXB72_RS03165	COG0768	penicillin binding
CXB72_RS03170	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CXB72_RS03175	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
CXB72_RS03190	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CXB72_RS03195	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
CXB72_RS03210	COG0390	transport system, permease component
CXB72_RS03215	COG4619	ABC transporter
CXB72_RS03245	COG0477	Major facilitator Superfamily
CXB72_RS03250	COG3842	ATPase activity
CXB72_RS03275	COG0395	ABC-type sugar transport system, permease component
CXB72_RS03285	COG2723	6-phospho-beta-galactosidase activity
CXB72_RS03290	COG1609	Transcriptional regulator
CXB72_RS03295	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CXB72_RS03300	COG3250	beta-galactosidase activity
CXB72_RS03305	COG3250	beta-galactosidase activity
CXB72_RS03310	COG1609	Transcriptional regulator
CXB72_RS03320	COG2190	(PTS) system
CXB72_RS03320	COG2211	Major facilitator Superfamily
CXB72_RS03325	COG1874	Beta-galactosidase
CXB72_RS03340	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
CXB72_RS03345	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
CXB72_RS03350	COG2017	converts alpha-aldose to the beta-anomer
CXB72_RS03390	COG2814	Major facilitator Superfamily
CXB72_RS03405	COG1653	transport
CXB72_RS03410	COG1175	transmembrane transport
CXB72_RS03415	COG0395	ABC-type sugar transport system, permease component
CXB72_RS03420	COG3842	ATPase activity
CXB72_RS03425	COG3345	alpha-galactosidase
CXB72_RS03430	COG0366	Alpha amylase catalytic
CXB72_RS03435	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
CXB72_RS03440	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
CXB72_RS03445	COG1461	Dihydroxyacetone kinase
CXB72_RS03450	COG2376	Dihydroxyacetone kinase
CXB72_RS03455	COG2357	RelA SpoT domain protein
CXB72_RS03460	COG0745	RESPONSE REGULATOR receiver
CXB72_RS03465	COG5002	protein histidine kinase activity
CXB72_RS03505	COG1335	isochorismatase
CXB72_RS03525	COG1902	pentaerythritol trinitrate reductase activity
CXB72_RS03550	COG3706	GGDEF domain
CXB72_RS03560	COG1053	succinate dehydrogenase
CXB72_RS03560	COG3976	FMN-binding domain protein
CXB72_RS03560	COG0431	NADPH-dependent FMN reductase
CXB72_RS03565	COG0583	DNA-binding transcription factor activity
CXB72_RS03590	COG2337	Toxic component of a toxin-antitoxin (TA) module
CXB72_RS03595	COG0702	epimerase
CXB72_RS03610	COG0446	pyridine nucleotide-disulphide oxidoreductase
CXB72_RS03625	COG2151	metal-sulfur cluster biosynthetic enzyme
CXB72_RS03630	COG1760	l-serine dehydratase
CXB72_RS03635	COG1760	l-serine dehydratase
CXB72_RS03670	COG0038	chloride channel
CXB72_RS03675	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
CXB72_RS03685	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
CXB72_RS03690	COG0284	orotidine-5'-phosphate decarboxylase activity
CXB72_RS03700	COG0167	dihydroorotate dehydrogenase activity
CXB72_RS03710	COG0540	Belongs to the ATCase OTCase family
CXB72_RS03715	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
CXB72_RS03720	COG0505	Belongs to the CarA family
CXB72_RS03725	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
CXB72_RS03735	COG4975	Glucose uptake
CXB72_RS03745	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CXB72_RS03750	COG2936	dipeptidyl-peptidase activity
CXB72_RS03785	COG0561	phosphatase activity
CXB72_RS03790	COG1136	(ABC) transporter
CXB72_RS03800	COG1393	Belongs to the ArsC family
CXB72_RS03840	COG3231	kanamycin kinase activity
CXB72_RS03845	COG4166	transmembrane transport
CXB72_RS03870	COG1942	4-Oxalocrotonate Tautomerase
CXB72_RS03875	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CXB72_RS03885	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CXB72_RS03890	COG0261	This protein binds to 23S rRNA in the presence of protein L20
CXB72_RS03895	COG0211	Belongs to the bacterial ribosomal protein bL27 family
CXB72_RS03900	COG0006	proline dipeptidase activity
CXB72_RS03905	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
CXB72_RS03910	COG1302	Protein conserved in bacteria
CXB72_RS03920	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
CXB72_RS03925	COG1570	exodeoxyribonuclease VII activity
CXB72_RS03930	COG1722	exodeoxyribonuclease VII activity
CXB72_RS03940	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
CXB72_RS03945	COG0497	DNA recombination
CXB72_RS03955	COG0194	GDP metabolic process
CXB72_RS03960	COG1758	RNA polymerase activity
CXB72_RS03965	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CXB72_RS03970	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CXB72_RS03975	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CXB72_RS03975	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CXB72_RS03980	COG0631	protein serine/threonine phosphatase activity
CXB72_RS03985	COG0515	serine threonine protein kinase
CXB72_RS03985	COG2815	serine threonine protein kinase
CXB72_RS03990	COG1162	GTPase activity
CXB72_RS03995	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CXB72_RS04010	COG0227	Belongs to the bacterial ribosomal protein bL28 family
CXB72_RS04025	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CXB72_RS04030	COG0416	fatty acid biosynthetic process
CXB72_RS04035	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CXB72_RS04045	COG4608	Belongs to the ABC transporter superfamily
CXB72_RS04050	COG0601	transmembrane transport
CXB72_RS04070	COG0571	ribonuclease III activity
CXB72_RS04075	COG1196	nuclear chromosome segregation
CXB72_RS04080	COG0552	protein localization to endoplasmic reticulum
CXB72_RS04095	COG0531	amino acid
CXB72_RS04100	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
CXB72_RS04105	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CXB72_RS04110	COG0228	four-way junction DNA binding
CXB72_RS04115	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
CXB72_RS04120	COG0336	Belongs to the RNA methyltransferase TrmD family
CXB72_RS04125	COG0335	large ribosomal subunit rRNA binding
CXB72_RS04140	COG0463	Glycosyl transferase, family 2
CXB72_RS04155	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CXB72_RS04160	COG4224	UPF0291 protein
CXB72_RS04165	COG3763	UPF0154 protein
CXB72_RS04170	COG1132	(ABC) transporter
CXB72_RS04175	COG1132	(ABC) transporter
CXB72_RS04180	COG3590	peptidase
CXB72_RS04185	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CXB72_RS04190	COG0204	Acyl-transferase
CXB72_RS04195	COG2827	Endonuclease containing a URI domain
CXB72_RS04200	COG0052	Belongs to the universal ribosomal protein uS2 family
CXB72_RS04205	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
CXB72_RS04210	COG0528	UMP kinase activity
CXB72_RS04215	COG0233	cytoplasmic translational termination
CXB72_RS04220	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CXB72_RS04225	COG4589	Belongs to the CDS family
CXB72_RS04230	COG0750	zinc metalloprotease
CXB72_RS04235	COG0442	prolyl-tRNA aminoacylation
CXB72_RS04245	COG0779	Required for maturation of 30S ribosomal subunits
CXB72_RS04250	COG0195	Participates in both transcription termination and antitermination
CXB72_RS04255	COG2740	Nucleic-acid-binding protein implicated in transcription termination
CXB72_RS04265	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
CXB72_RS04270	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
CXB72_RS04275	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
CXB72_RS04280	COG0196	riboflavin kinase activity
CXB72_RS04290	COG0488	(ABC) transporter
CXB72_RS04295	COG1420	regulation of RNA biosynthetic process
CXB72_RS04300	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
CXB72_RS04305	COG0443	Heat shock 70 kDa protein
CXB72_RS04310	COG0484	heat shock protein binding
CXB72_RS04315	COG0481	GTPase activity
CXB72_RS04320	COG3764	Sortase (surface protein transpeptidase)
CXB72_RS04325	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
CXB72_RS04325	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
CXB72_RS04330	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CXB72_RS04345	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
CXB72_RS04355	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CXB72_RS04375	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
CXB72_RS04380	COG0583	DNA-binding transcription factor activity
CXB72_RS04420	COG1114	Component of the transport system for branched-chain amino acids
CXB72_RS04430	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CXB72_RS04445	COG0110	maltose O-acetyltransferase activity
CXB72_RS04455	COG4166	transmembrane transport
CXB72_RS04460	COG0527	aspartate kinase activity
CXB72_RS04485	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CXB72_RS04750	COG3299	homolog of phage Mu protein gp47
CXB72_RS04805	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CXB72_RS04815	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
CXB72_RS04820	COG0828	Belongs to the bacterial ribosomal protein bS21 family
CXB72_RS04830	COG1702	phosphate starvation-inducible protein PhoH
CXB72_RS04835	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
CXB72_RS04840	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
CXB72_RS04845	COG1381	Involved in DNA repair and RecF pathway recombination
CXB72_RS04850	COG0752	glycyl-tRNA synthetase alpha subunit
CXB72_RS04855	COG0751	glycine-tRNA ligase activity
CXB72_RS04860	COG0358	DNA primase activity
CXB72_RS04865	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CXB72_RS04880	COG0494	nUDIX hydrolase
CXB72_RS04885	COG2384	SAM-dependent methyltransferase
CXB72_RS04890	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
CXB72_RS04895	COG2195	Cleaves the N-terminal amino acid of tripeptides
CXB72_RS04955	COG1725	Transcriptional regulator
CXB72_RS04960	COG1131	(ABC) transporter
CXB72_RS05000	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CXB72_RS05000	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
CXB72_RS05005	COG1104	cysteine desulfurase activity
CXB72_RS05020	COG1737	Transcriptional regulator
CXB72_RS05045	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
CXB72_RS05050	COG1074	ATP-dependent DNA helicase activity
CXB72_RS05065	COG0017	Asparaginyl-tRNA synthetase
CXB72_RS05075	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CXB72_RS05080	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CXB72_RS05085	COG3331	DNA recombination
CXB72_RS05090	COG4474	Belongs to the UPF0398 family
CXB72_RS05095	COG3599	regulation of cell shape
CXB72_RS05105	COG0116	Belongs to the methyltransferase superfamily
CXB72_RS05120	COG2759	Belongs to the formate--tetrahydrofolate ligase family
CXB72_RS05130	COG0564	pseudouridine synthase activity
CXB72_RS05135	COG0505	Belongs to the CarA family
CXB72_RS05140	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
CXB72_RS05155	COG1307	EDD domain protein, DegV family
CXB72_RS05170	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
CXB72_RS05195	COG1846	Transcriptional regulator
CXB72_RS05210	COG1132	(ABC) transporter
CXB72_RS05245	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CXB72_RS05250	COG1227	inorganic diphosphatase activity
CXB72_RS05255	COG0583	DNA-binding transcription factor activity
CXB72_RS05265	COG0187	DNA topoisomerase II activity
CXB72_RS05270	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
CXB72_RS05280	COG2855	membrane
CXB72_RS05295	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CXB72_RS05350	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CXB72_RS05370	COG4975	Glucose uptake
CXB72_RS05375	COG0667	Aldo Keto reductase
CXB72_RS05380	COG1247	-acetyltransferase
CXB72_RS05385	COG1028	Short-chain dehydrogenase reductase Sdr
CXB72_RS05415	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
CXB72_RS05420	COG1854	S-ribosylhomocysteine lyase activity
CXB72_RS05425	COG0626	cystathionine gamma-synthase activity
CXB72_RS05430	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CXB72_RS05435	COG0531	amino acid
CXB72_RS05455	COG1854	S-ribosylhomocysteine lyase activity
CXB72_RS05460	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
CXB72_RS05465	COG1376	ErfK ybiS ycfS ynhG family protein
CXB72_RS05470	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
CXB72_RS05475	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CXB72_RS05485	COG0281	malic enzyme
CXB72_RS05545	COG1011	Hydrolase
CXB72_RS05560	COG0588	phosphoglycerate mutase activity
CXB72_RS05615	COG1373	ATPase (AAA superfamily
CXB72_RS05665	COG1051	belongs to the nudix hydrolase family
CXB72_RS05685	COG2814	Major facilitator Superfamily
CXB72_RS05710	COG2159	amidohydrolase
CXB72_RS05720	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
CXB72_RS05730	COG1126	abc transporter atp-binding protein
CXB72_RS05735	COG0765	amino acid transport
CXB72_RS05740	COG0765	amino acid transport
CXB72_RS05765	COG1114	Component of the transport system for branched-chain amino acids
CXB72_RS05795	COG0456	acetyltransferase
CXB72_RS05805	COG0656	L-ascorbic acid biosynthetic process
CXB72_RS05810	COG0656	L-ascorbic acid biosynthetic process
CXB72_RS05820	COG0583	DNA-binding transcription factor activity
CXB72_RS05845	COG3321	synthase
CXB72_RS05845	COG0604	alcohol dehydrogenase
CXB72_RS05860	COG1174	glycine betaine transport
CXB72_RS05870	COG1959	2 iron, 2 sulfur cluster binding
CXB72_RS05880	COG0477	Major facilitator Superfamily
CXB72_RS05915	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
CXB72_RS05945	COG1288	antiporter activity
CXB72_RS05955	COG0561	phosphatase activity
CXB72_RS05965	COG3883	PFAM NLP P60 protein
CXB72_RS05965	COG0791	NLP P60 protein
CXB72_RS05975	COG1473	amidohydrolase
CXB72_RS05980	COG4221	oxidoreductase activity
CXB72_RS05990	COG0656	L-ascorbic acid biosynthetic process
CXB72_RS05995	COG0656	L-ascorbic acid biosynthetic process
CXB72_RS06035	COG1621	beta-fructofuranosidase activity
CXB72_RS06040	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CXB72_RS06040	COG1263	PTS System
CXB72_RS06085	COG0366	Alpha amylase catalytic
CXB72_RS06090	COG2188	Transcriptional regulator
CXB72_RS06095	COG1263	PTS System
CXB72_RS06095	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CXB72_RS06095	COG2190	(PTS) system
CXB72_RS06135	COG2040	homocysteine
CXB72_RS06140	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CXB72_RS06150	COG0514	ATP-dependent DNA helicase (RecQ)
CXB72_RS06155	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CXB72_RS06160	COG0569	domain protein
CXB72_RS06165	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
CXB72_RS06175	COG0531	amino acid
CXB72_RS06185	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CXB72_RS06190	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CXB72_RS06220	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
CXB72_RS06235	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
CXB72_RS06240	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CXB72_RS06245	COG0758	DNA mediated transformation
CXB72_RS06250	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CXB72_RS06255	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
CXB72_RS06260	COG0025	NhaP-type Na H and K H
CXB72_RS06265	COG4479	Belongs to the UPF0346 family
CXB72_RS06270	COG1307	EDD domain protein, DegV family
CXB72_RS06275	COG1272	protein, Hemolysin III
CXB72_RS06280	COG0617	tRNA 3'-terminal CCA addition
CXB72_RS06285	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CXB72_RS06300	COG1160	GTP binding
CXB72_RS06305	COG0539	negative regulation of cytoplasmic translation
CXB72_RS06310	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
CXB72_RS06315	COG5632	N-Acetylmuramoyl-L-alanine amidase
CXB72_RS06315	COG3409	Peptidoglycan-binding domain 1 protein
CXB72_RS06320	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
CXB72_RS06325	COG1187	pseudouridine synthase activity
CXB72_RS06335	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
CXB72_RS06340	COG0456	acetyltransferase
CXB72_RS06350	COG2996	Protein conserved in bacteria
CXB72_RS06360	COG0205	6-phosphofructokinase activity
CXB72_RS06365	COG0587	DNA-directed DNA polymerase activity
CXB72_RS06375	COG0737	Belongs to the 5'-nucleotidase family
CXB72_RS06380	COG0333	Belongs to the bacterial ribosomal protein bL32 family
CXB72_RS06390	COG0300	oxidoreductase activity
CXB72_RS06395	COG1234	tRNA 3'-trailer cleavage
CXB72_RS06400	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
CXB72_RS06400	COG2755	lipolytic protein G-D-S-L family
CXB72_RS06405	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
CXB72_RS06410	COG0322	excinuclease ABC activity
CXB72_RS06415	COG0586	Pfam SNARE associated Golgi protein
CXB72_RS06425	COG0531	amino acid
CXB72_RS06430	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CXB72_RS06435	COG0561	phosphatase activity
CXB72_RS06440	COG0656	L-ascorbic acid biosynthetic process
CXB72_RS06445	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CXB72_RS06450	COG0436	Aminotransferase
CXB72_RS06455	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
CXB72_RS06460	COG0124	histidyl-tRNA synthetase
CXB72_RS06465	COG1490	D-aminoacyl-tRNA deacylase activity
CXB72_RS06470	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CXB72_RS06480	COG2264	protein methyltransferase activity
CXB72_RS06485	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CXB72_RS06515	COG4720	Psort location CytoplasmicMembrane, score
CXB72_RS06520	COG1122	ATPase activity
CXB72_RS06530	COG2707	UPF0756 membrane protein
CXB72_RS06550	COG3052	prosthetic group binding
CXB72_RS06560	COG2267	carboxylic ester hydrolase activity
CXB72_RS06565	COG0471	metal ion transport
CXB72_RS06570	COG3579	cysteine-type endopeptidase activity
CXB72_RS06575	COG0039	L-malate dehydrogenase activity
CXB72_RS06585	COG1053	succinate dehydrogenase
CXB72_RS06595	COG2011	ABC-type metal ion transport system permease component
CXB72_RS06600	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CXB72_RS06610	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
CXB72_RS06620	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
CXB72_RS06625	COG1113	amino acid transport
CXB72_RS06670	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
CXB72_RS06685	COG0148	phosphopyruvate hydratase activity
CXB72_RS06700	COG1940	carbohydrate kinase activity
CXB72_RS06705	COG2723	6-phospho-beta-galactosidase activity
CXB72_RS06710	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CXB72_RS06720	COG2188	Transcriptional regulator
CXB72_RS06725	COG2723	6-phospho-beta-galactosidase activity
CXB72_RS06745	COG1447	Phosphotransferase system cellobiose-specific component IIA
CXB72_RS06750	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CXB72_RS06755	COG2188	Transcriptional regulator
CXB72_RS06760	COG2723	6-phospho-beta-galactosidase activity
CXB72_RS06770	COG2261	transglycosylase associated protein
CXB72_RS06805	COG1957	nucleoside hydrolase
CXB72_RS06820	COG1053	succinate dehydrogenase
CXB72_RS06820	COG0431	NADPH-dependent FMN reductase
CXB72_RS06820	COG3976	FMN-binding domain protein
CXB72_RS06830	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CXB72_RS06835	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CXB72_RS06840	COG0436	Aminotransferase
CXB72_RS06845	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
CXB72_RS06850	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CXB72_RS06855	COG1473	amidohydrolase
CXB72_RS06860	COG2171	N-acyltransferase activity
CXB72_RS06865	COG0019	diaminopimelate decarboxylase activity
CXB72_RS06870	COG0527	aspartate kinase activity
CXB72_RS06880	COG0218	Necessary for normal cell division and for the maintenance of normal septation
CXB72_RS06885	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
CXB72_RS06890	COG0544	peptidyl-prolyl cis-trans isomerase activity
CXB72_RS06895	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CXB72_RS06910	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
CXB72_RS06915	COG0268	Binds directly to 16S ribosomal RNA
CXB72_RS06920	COG1466	dna polymerase III delta subunit
CXB72_RS06925	COG0658	competence protein
CXB72_RS06925	COG2333	competence protein COMEC
CXB72_RS06930	COG1555	photosystem II stabilization
CXB72_RS06930	COG1596	polysaccharide export
CXB72_RS06935	COG3480	Lon protease (S16) C-terminal proteolytic domain
CXB72_RS06940	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
CXB72_RS06945	COG0742	ribosomal rna small subunit methyltransferase
CXB72_RS06955	COG0772	Belongs to the SEDS family
CXB72_RS06960	COG1217	gtp-binding protein TYPA
CXB72_RS06965	COG0242	peptide deformylase activity
CXB72_RS06970	COG5503	Protein of unknown function (DUF1447)
CXB72_RS06980	COG1597	lipid kinase activity
CXB72_RS06990	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CXB72_RS07000	COG0406	alpha-ribazole phosphatase activity
CXB72_RS07005	COG0482	sulfurtransferase activity
CXB72_RS07015	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CXB72_RS07025	COG0494	nUDIX hydrolase
CXB72_RS07030	COG1278	Cold shock
CXB72_RS07035	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
CXB72_RS07040	COG3599	regulation of cell shape
CXB72_RS07055	COG1799	cell septum assembly
CXB72_RS07060	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CXB72_RS07070	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
CXB72_RS07075	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CXB72_RS07080	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
CXB72_RS07085	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CXB72_RS07090	COG0768	penicillin binding
CXB72_RS07100	COG0275	rRNA processing
CXB72_RS07105	COG2001	Belongs to the MraZ family
CXB72_RS07125	COG1792	Involved in formation and maintenance of cell shape
CXB72_RS07130	COG1077	Cell shape determining protein MreB Mrl
CXB72_RS07135	COG2003	Belongs to the UPF0758 family
CXB72_RS07140	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CXB72_RS07150	COG0525	valine-tRNA ligase activity
CXB72_RS07165	COG1187	pseudouridine synthase activity
CXB72_RS07170	COG0301	tRNA thio-modification
CXB72_RS07175	COG1104	cysteine desulfurase activity
CXB72_RS07180	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
CXB72_RS07185	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
CXB72_RS07195	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CXB72_RS07210	COG0589	response to stress
CXB72_RS07215	COG0772	Belongs to the SEDS family
CXB72_RS07225	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
CXB72_RS07230	COG1077	Cell shape determining protein MreB Mrl
CXB72_RS07240	COG0355	proton-transporting ATP synthase activity, rotational mechanism
CXB72_RS07245	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
CXB72_RS07250	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
CXB72_RS07255	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
CXB72_RS07260	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CXB72_RS07265	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
CXB72_RS07270	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CXB72_RS07275	COG0356	it plays a direct role in the translocation of protons across the membrane
CXB72_RS07280	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
CXB72_RS07285	COG0009	L-threonylcarbamoyladenylate synthase
CXB72_RS07290	COG2890	protein-(glutamine-N5) methyltransferase activity
CXB72_RS07295	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
CXB72_RS07300	COG1435	thymidine kinase activity
CXB72_RS07305	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
CXB72_RS07320	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CXB72_RS07325	COG0477	Major facilitator Superfamily
CXB72_RS07330	COG0166	Belongs to the GPI family
CXB72_RS07340	COG1368	sulfuric ester hydrolase activity
CXB72_RS07355	COG5002	protein histidine kinase activity
CXB72_RS07355	COG3850	Histidine kinase
CXB72_RS07360	COG0745	RESPONSE REGULATOR receiver
CXB72_RS07370	COG1482	cell wall glycoprotein biosynthetic process
CXB72_RS07380	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
CXB72_RS07400	COG0827	DNA restriction-modification system
CXB72_RS07430	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CXB72_RS07435	COG0217	transcriptional regulatory protein
CXB72_RS07455	COG0531	amino acid
CXB72_RS07470	COG2190	(PTS) system
CXB72_RS07470	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CXB72_RS07470	COG1263	PTS System
CXB72_RS07480	COG1929	Belongs to the glycerate kinase type-1 family
CXB72_RS07485	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CXB72_RS07495	COG0561	phosphatase activity
CXB72_RS07500	COG0561	phosphatase activity
CXB72_RS07505	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CXB72_RS07510	COG4856	YbbR-like protein
CXB72_RS07525	COG1176	ABC-type spermidine putrescine transport system, permease component I
CXB72_RS07530	COG1176	ABC-type spermidine putrescine transport system, permease component I
CXB72_RS07535	COG3842	ATPase activity
CXB72_RS07540	COG0812	UDP-N-acetylmuramate dehydrogenase activity
CXB72_RS07550	COG0802	atpase or kinase
CXB72_RS07555	COG0280	phosphate acetyltransferase
CXB72_RS07560	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
CXB72_RS07565	COG0561	phosphatase activity
CXB72_RS07575	COG0149	triose-phosphate isomerase activity
CXB72_RS07580	COG0126	phosphoglycerate kinase activity
CXB72_RS07590	COG2390	Transcriptional regulator
CXB72_RS07600	COG0531	amino acid
CXB72_RS07610	COG0740	serine-type endopeptidase activity
CXB72_RS07615	COG1481	regulation of sporulation
CXB72_RS07620	COG0391	Required for morphogenesis under gluconeogenic growth conditions
CXB72_RS07625	COG1660	Displays ATPase and GTPase activities
CXB72_RS07635	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CXB72_RS07640	COG0556	nucleotide-excision repair
CXB72_RS07645	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CXB72_RS07650	COG0366	Alpha amylase catalytic
CXB72_RS07650	COG3103	Sh3 type 3 domain protein
CXB72_RS07655	COG0058	SHG alpha-glucan phosphorylase activity
CXB72_RS07660	COG0297	glycogen (starch) synthase activity
CXB72_RS07665	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
CXB72_RS07670	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
CXB72_RS07675	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
CXB72_RS07680	COG0492	ferredoxin-NADP+ reductase activity
CXB72_RS07685	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
CXB72_RS07690	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
CXB72_RS07695	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
CXB72_RS07710	COG0653	protein targeting
CXB72_RS07725	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
CXB72_RS07730	COG1739	Uncharacterized protein family UPF0029
CXB72_RS07735	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CXB72_RS07740	COG1418	mRNA catabolic process
CXB72_RS07745	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
CXB72_RS07750	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CXB72_RS07755	COG1426	Protein conserved in bacteria
CXB72_RS07760	COG1028	Short-chain dehydrogenase reductase Sdr
CXB72_RS07765	COG0612	Peptidase, M16
CXB72_RS07775	COG1674	ftsk spoiiie
CXB72_RS07790	COG0628	permease
CXB72_RS07800	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
CXB72_RS07805	COG2706	6-phosphogluconolactonase activity
CXB72_RS07820	COG0564	pseudouridine synthase activity
CXB72_RS07825	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CXB72_RS07830	COG2357	RelA SpoT domain protein
CXB72_RS07840	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CXB72_RS07850	COG4862	establishment of competence for transformation
CXB72_RS07855	COG1393	Belongs to the ArsC family
CXB72_RS07865	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CXB72_RS07875	COG0542	response to heat
CXB72_RS07885	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
CXB72_RS07910	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CXB72_RS07920	COG1073	alpha beta
CXB72_RS07930	COG3425	synthase
CXB72_RS07940	COG0183	Belongs to the thiolase family
CXB72_RS07945	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CXB72_RS07950	COG1295	ribonuclease BN
CXB72_RS07955	COG0024	Methionine aminopeptidase
CXB72_RS07960	COG0716	FMN binding
CXB72_RS07970	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
CXB72_RS07990	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CXB72_RS08005	COG0531	amino acid
CXB72_RS08015	COG1253	flavin adenine dinucleotide binding
CXB72_RS08030	COG1263	PTS System
CXB72_RS08030	COG2190	(PTS) system
CXB72_RS08030	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CXB72_RS08040	COG1737	Transcriptional regulator
CXB72_RS08045	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CXB72_RS08045	COG1263	PTS System
CXB72_RS08050	COG0561	phosphatase activity
CXB72_RS08075	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
CXB72_RS08100	COG0561	phosphatase activity
CXB72_RS08110	COG2188	Transcriptional regulator
CXB72_RS08120	COG3158	transport of potassium into the cell
CXB72_RS08125	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
CXB72_RS08155	COG0765	amino acid transport
CXB72_RS08160	COG0765	amino acid transport
CXB72_RS08165	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CXB72_RS08175	COG0572	uridine kinase
CXB72_RS08185	COG1132	(ABC) transporter
CXB72_RS08190	COG1132	(ABC) transporter
CXB72_RS08200	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CXB72_RS08210	COG0488	(ABC) transporter
CXB72_RS08225	COG2814	Major facilitator Superfamily
CXB72_RS08230	COG2814	Major facilitator Superfamily
CXB72_RS08235	COG0561	phosphatase activity
CXB72_RS08240	COG0561	phosphatase activity
CXB72_RS08270	COG0656	L-ascorbic acid biosynthetic process
CXB72_RS08290	COG4716	Myosin-crossreactive antigen
CXB72_RS08295	COG1309	transcriptional regulator
CXB72_RS08305	COG2814	Major facilitator Superfamily
CXB72_RS08365	COG1573	uracil-dna glycosylase
CXB72_RS08370	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CXB72_RS08380	COG2217	Heavy metal translocating P-type atpase
CXB72_RS08400	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CXB72_RS08405	COG1757	Na H antiporter
CXB72_RS08415	COG0670	Belongs to the BI1 family
CXB72_RS08420	COG1597	lipid kinase activity
CXB72_RS08425	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CXB72_RS08430	COG0154	amidase activity
CXB72_RS08435	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CXB72_RS08440	COG4851	CamS sex pheromone cAM373 precursor
CXB72_RS08445	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CXB72_RS08455	COG1705	Flagellar rod assembly protein muramidase FlgJ
CXB72_RS08465	COG3091	SprT-like family
CXB72_RS08480	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
CXB72_RS08495	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
CXB72_RS08505	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
CXB72_RS08515	COG2188	Transcriptional regulator
CXB72_RS08550	COG0584	glycerophosphoryl diester phosphodiesterase
CXB72_RS08560	COG0588	phosphoglycerate mutase activity
CXB72_RS08565	COG0588	phosphoglycerate mutase activity
CXB72_RS08585	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CXB72_RS08630	COG0004	ammonium transporteR
CXB72_RS08640	COG1111	helicase
CXB72_RS08640	COG1205	dead DEAH box helicase
CXB72_RS08660	COG0494	nUDIX hydrolase
CXB72_RS08670	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CXB72_RS08675	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CXB72_RS08680	COG1454	alcohol dehydrogenase
CXB72_RS08680	COG1012	belongs to the aldehyde dehydrogenase family
CXB72_RS08685	COG1113	amino acid transport
CXB72_RS08690	COG0110	maltose O-acetyltransferase activity
CXB72_RS08695	COG0583	DNA-binding transcription factor activity
CXB72_RS08705	COG3716	PTS system mannose fructose sorbose family IID component
CXB72_RS08710	COG3715	PTS system
CXB72_RS08745	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
CXB72_RS08750	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CXB72_RS08755	COG0398	Pfam SNARE associated Golgi protein
CXB72_RS08775	COG1012	belongs to the aldehyde dehydrogenase family
CXB72_RS08795	COG1033	growth of symbiont in host cell
CXB72_RS08795	COG2409	Drug exporters of the RND superfamily
CXB72_RS08830	COG1175	transmembrane transport
CXB72_RS08850	COG2176	DNA-directed DNA polymerase activity
CXB72_RS08900	COG1132	(ABC) transporter
CXB72_RS08905	COG2267	carboxylic ester hydrolase activity
CXB72_RS08910	COG0745	RESPONSE REGULATOR receiver
CXB72_RS08930	COG1846	Transcriptional regulator
CXB72_RS08940	COG4166	transmembrane transport
CXB72_RS08955	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
CXB72_RS08975	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CXB72_RS08980	COG1126	abc transporter atp-binding protein
CXB72_RS08985	COG0765	amino acid transport
CXB72_RS08990	COG3973	AAA domain
CXB72_RS09000	COG0588	phosphoglycerate mutase activity
CXB72_RS09010	COG1136	(ABC) transporter
CXB72_RS09045	COG0252	asparaginase activity
CXB72_RS09105	COG0708	Exodeoxyribonuclease III
CXB72_RS09110	COG2207	Transcriptional regulator
CXB72_RS09120	COG1737	Transcriptional regulator
CXB72_RS09130	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
CXB72_RS09135	COG1263	PTS System
CXB72_RS09135	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CXB72_RS09140	COG2723	6-phospho-beta-galactosidase activity
CXB72_RS09145	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CXB72_RS09145	COG1263	PTS System
CXB72_RS09145	COG2190	(PTS) system
CXB72_RS09150	COG3711	transcriptional antiterminator
CXB72_RS09210	COG0191	fructose-bisphosphate aldolase activity
CXB72_RS09215	COG3414	Phosphotransferase system galactitol-specific IIB component
CXB72_RS09220	COG3775	system Galactitol-specific IIC component
CXB72_RS09245	COG5290	Psort location Cytoplasmic, score
CXB72_RS09270	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CXB72_RS09290	COG1215	transferase activity, transferring glycosyl groups
CXB72_RS09300	COG0562	UDP-galactopyranose mutase
CXB72_RS09305	COG1216	Glycosyl transferase, family 2
CXB72_RS09315	COG0438	transferase activity, transferring glycosyl groups
CXB72_RS09330	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CXB72_RS09335	COG4464	protein tyrosine phosphatase activity
CXB72_RS09340	COG0489	protein tyrosine kinase activity
CXB72_RS09350	COG1316	TRANSCRIPTIONal
CXB72_RS09355	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CXB72_RS09370	COG0791	NLP P60 protein
CXB72_RS09375	COG0791	NLP P60 protein
CXB72_RS09380	COG0791	NLP P60 protein
CXB72_RS09405	COG1780	Probably involved in ribonucleotide reductase function
CXB72_RS09420	COG4990	cell redox homeostasis
CXB72_RS09425	COG2151	metal-sulfur cluster biosynthetic enzyme
CXB72_RS09430	COG0719	Fe-S assembly protein
CXB72_RS09435	COG0822	iron-sulfur transferase activity
CXB72_RS09440	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CXB72_RS09445	COG0719	Fe-S assembly protein
CXB72_RS09470	COG0488	(ABC) transporter
CXB72_RS09485	COG1316	TRANSCRIPTIONal
CXB72_RS09490	COG1164	Oligoendopeptidase f
CXB72_RS09500	COG1620	l-lactate permease
CXB72_RS09510	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CXB72_RS09515	COG1121	(ABC) transporter
CXB72_RS09525	COG0640	Transcriptional regulator
CXB72_RS09540	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CXB72_RS09540	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CXB72_RS09540	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CXB72_RS09545	COG1105	Belongs to the carbohydrate kinase PfkB family
CXB72_RS09550	COG1349	DNA-binding transcription factor activity
CXB72_RS09555	COG1668	transmembrane transport
CXB72_RS09560	COG4152	abc transporter atp-binding protein
CXB72_RS09580	COG3655	Transcriptional regulator
CXB72_RS09655	COG1794	racemase activity, acting on amino acids and derivatives
CXB72_RS09660	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CXB72_RS09675	COG1132	(ABC) transporter
CXB72_RS09680	COG1132	(ABC) transporter
CXB72_RS09690	COG0012	GTP binding
CXB72_RS09695	COG4481	Protein conserved in bacteria
CXB72_RS09700	COG1475	DNA binding
CXB72_RS09705	COG1192	Involved in chromosome partitioning
CXB72_RS09715	COG0357	Ribosomal RNA small subunit methyltransferase G
CXB72_RS09730	COG0431	NADPH-dependent FMN reductase
CXB72_RS09735	COG0431	NADPH-dependent FMN reductase
CXB72_RS09765	COG1136	(ABC) transporter
CXB72_RS09790	COG3022	response to hydroperoxide
CXB72_RS09800	COG3104	oligopeptide transport
CXB72_RS09815	COG3104	oligopeptide transport
CXB72_RS09820	COG0308	aminopeptidase N
CXB72_RS09855	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
CXB72_RS09880	COG3833	ABC-type maltose transport systems, permease component
CXB72_RS09895	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CXB72_RS09905	COG0366	Alpha amylase catalytic
CXB72_RS09910	COG0366	Alpha amylase catalytic
CXB72_RS09915	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CXB72_RS09920	COG1609	Transcriptional regulator
CXB72_RS09925	COG2365	Tyrosine phosphatase family
CXB72_RS09930	COG1132	(ABC) transporter
CXB72_RS09940	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CXB72_RS09945	COG0351	phosphomethylpyrimidine kinase
CXB72_RS09955	COG3442	glutamine amidotransferase
CXB72_RS09960	COG0791	NLP P60 protein
CXB72_RS09975	COG0697	spore germination
CXB72_RS09990	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CXB72_RS09995	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
CXB72_RS10000	COG0516	GMP reductase activity
CXB72_RS10025	COG2502	aspartate--ammonia ligase
CXB72_RS10035	COG0492	ferredoxin-NADP+ reductase activity
CXB72_RS10040	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CXB72_RS10060	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
CXB72_RS10065	COG1113	amino acid transport
CXB72_RS10070	COG1113	amino acid transport
CXB72_RS10085	COG0542	response to heat
CXB72_RS10100	COG1136	(ABC) transporter
CXB72_RS10100	COG0577	efflux transmembrane transporter activity
CXB72_RS10115	COG2244	polysaccharide biosynthetic process
CXB72_RS10145	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
CXB72_RS10150	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CXB72_RS10155	COG1696	Membrane protein involved in D-alanine export
CXB72_RS10160	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CXB72_RS10180	COG0516	GMP reductase activity
CXB72_RS10180	COG0517	IMP dehydrogenase activity
CXB72_RS10185	COG2217	Heavy metal translocating P-type atpase
CXB72_RS10205	COG1132	(ABC) transporter
CXB72_RS10230	COG1396	sequence-specific DNA binding
CXB72_RS10245	COG1136	(ABC) transporter
CXB72_RS10245	COG0577	efflux transmembrane transporter activity
CXB72_RS10245	COG1136	(ABC) transporter
CXB72_RS10245	COG0577	efflux transmembrane transporter activity
CXB72_RS10255	COG1744	ABC transporter substrate-binding protein PnrA-like
CXB72_RS10260	COG1744	ABC transporter substrate-binding protein PnrA-like
CXB72_RS10265	COG3845	ABC transporter
CXB72_RS10270	COG4603	Belongs to the binding-protein-dependent transport system permease family
CXB72_RS10275	COG1079	Belongs to the binding-protein-dependent transport system permease family
CXB72_RS10280	COG0656	L-ascorbic acid biosynthetic process
CXB72_RS10285	COG0363	glucosamine-6-phosphate deaminase activity
CXB72_RS10290	COG1428	Deoxynucleoside kinase
CXB72_RS10295	COG1428	Deoxynucleoside kinase
CXB72_RS10300	COG0561	phosphatase activity
CXB72_RS10305	COG2252	PERMEase
CXB72_RS10310	COG0789	Transcriptional regulator
CXB72_RS10315	COG2252	PERMEase
CXB72_RS10320	COG2267	carboxylic ester hydrolase activity
CXB72_RS10325	COG4166	transmembrane transport
CXB72_RS10330	COG2252	PERMEase
CXB72_RS10340	COG4166	transmembrane transport
CXB72_RS10360	COG2217	Heavy metal translocating P-type atpase
CXB72_RS10375	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CXB72_RS10400	COG0028	Belongs to the TPP enzyme family
CXB72_RS10405	COG0445	tRNA wobble uridine modification
CXB72_RS10410	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
CXB72_RS10415	COG0706	membrane insertase activity
CXB72_RS10420	COG0594	ribonuclease P activity
CXB72_RS10425	COG0230	Belongs to the bacterial ribosomal protein bL34 family