locus-tag	class	description
E6A57_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
E6A57_RS00010	COG0592	DNA-directed DNA polymerase activity
E6A57_RS00015	COG2501	S4 domain
E6A57_RS00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
E6A57_RS00025	COG0187	DNA topoisomerase II activity
E6A57_RS00030	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
E6A57_RS00035	COG0360	Binds together with S18 to 16S ribosomal RNA
E6A57_RS00040	COG0629	single-stranded DNA binding
E6A57_RS00045	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
E6A57_RS00055	COG0359	binds to the 23S rRNA
E6A57_RS00060	COG0305	Participates in initiation and elongation during chromosome replication
E6A57_RS00070	COG1307	EDD domain protein, DegV family
E6A57_RS00075	COG1940	carbohydrate kinase activity
E6A57_RS00085	COG2261	transglycosylase associated protein
E6A57_RS00095	COG1285	pathogenesis
E6A57_RS00150	COG0628	permease
E6A57_RS00200	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
E6A57_RS00215	COG1011	Hydrolase
E6A57_RS00220	COG0598	Magnesium transport protein CorA
E6A57_RS00225	COG0656	L-ascorbic acid biosynthetic process
E6A57_RS00235	COG0561	phosphatase activity
E6A57_RS00240	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
E6A57_RS00255	COG0708	Exodeoxyribonuclease III
E6A57_RS00260	COG0531	amino acid
E6A57_RS00330	COG1442	glycosyl transferase family 8
E6A57_RS00340	COG1442	glycosyl transferase family 8
E6A57_RS00365	COG0745	RESPONSE REGULATOR receiver
E6A57_RS00370	COG5002	protein histidine kinase activity
E6A57_RS00385	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
E6A57_RS00390	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
E6A57_RS00395	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
E6A57_RS00405	COG2267	carboxylic ester hydrolase activity
E6A57_RS00415	COG1122	ATPase activity
E6A57_RS00440	COG0501	Belongs to the peptidase M48B family
E6A57_RS00445	COG1704	LemA family
E6A57_RS00450	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
E6A57_RS00475	COG1215	transferase activity, transferring glycosyl groups
E6A57_RS00495	COG3152	Membrane
E6A57_RS00500	COG1126	abc transporter atp-binding protein
E6A57_RS00505	COG0765	amino acid transport
E6A57_RS00510	COG2094	Belongs to the DNA glycosylase MPG family
E6A57_RS00515	COG3189	MarR family transcriptional regulator
E6A57_RS00520	COG0861	Integral membrane protein TerC family
E6A57_RS00530	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
E6A57_RS00540	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
E6A57_RS00550	COG0328	RNA-DNA hybrid ribonuclease activity
E6A57_RS00560	COG1216	Glycosyl transferase, family 2
E6A57_RS00575	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
E6A57_RS00590	COG0765	amino acid transport
E6A57_RS00595	COG1126	abc transporter atp-binding protein
E6A57_RS00605	COG1181	Belongs to the D-alanine--D-alanine ligase family
E6A57_RS00675	COG1131	(ABC) transporter
E6A57_RS00705	COG2365	Tyrosine phosphatase family
E6A57_RS00710	COG0589	response to stress
E6A57_RS00720	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
E6A57_RS00730	COG3639	organic phosphonate transmembrane transporter activity
E6A57_RS00735	COG0519	Catalyzes the synthesis of GMP from XMP
E6A57_RS00750	COG0367	asparagine synthase
E6A57_RS00765	COG0602	queuosine metabolic process
E6A57_RS00770	COG2151	metal-sulfur cluster biosynthetic enzyme
E6A57_RS00780	COG2814	Major facilitator Superfamily
E6A57_RS00785	COG3590	peptidase
E6A57_RS00790	COG3158	transport of potassium into the cell
E6A57_RS00910	COG2217	Heavy metal translocating P-type atpase
E6A57_RS00935	COG1705	Flagellar rod assembly protein muramidase FlgJ
E6A57_RS00935	COG1388	LysM domain
E6A57_RS00945	COG0475	glutathione-regulated potassium exporter activity
E6A57_RS00945	COG0569	domain protein
E6A57_RS00955	COG0673	inositol 2-dehydrogenase activity
E6A57_RS00970	COG0588	phosphoglycerate mutase activity
E6A57_RS00980	COG1316	TRANSCRIPTIONal
E6A57_RS00985	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
E6A57_RS00990	COG1368	sulfuric ester hydrolase activity
E6A57_RS00995	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
E6A57_RS01010	COG3579	cysteine-type endopeptidase activity
E6A57_RS01015	COG1418	mRNA catabolic process
E6A57_RS01020	COG4166	transmembrane transport
E6A57_RS01025	COG4166	transmembrane transport
E6A57_RS01035	COG0601	transmembrane transport
E6A57_RS01040	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
E6A57_RS01045	COG0444	Belongs to the ABC transporter superfamily
E6A57_RS01050	COG4608	Belongs to the ABC transporter superfamily
E6A57_RS01055	COG3579	cysteine-type endopeptidase activity
E6A57_RS01065	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
E6A57_RS01090	COG2131	deaminase
E6A57_RS01100	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
E6A57_RS01115	COG1132	(ABC) transporter
E6A57_RS01120	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
E6A57_RS01120	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
E6A57_RS01125	COG0084	hydrolase, TatD family'
E6A57_RS01135	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
E6A57_RS01140	COG4466	Protein conserved in bacteria
E6A57_RS01145	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
E6A57_RS01150	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
E6A57_RS01165	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
E6A57_RS01180	COG1078	dGTPase activity
E6A57_RS01190	COG3343	RNA polymerase activity
E6A57_RS01195	COG0504	CTP synthase activity
E6A57_RS01200	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
E6A57_RS01210	COG4690	dipeptidase activity
E6A57_RS01220	COG2233	PERMEase
E6A57_RS01225	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
E6A57_RS01235	COG0519	Catalyzes the synthesis of GMP from XMP
E6A57_RS01280	COG1733	regulation of RNA biosynthetic process
E6A57_RS01285	COG0604	alcohol dehydrogenase
E6A57_RS01295	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
E6A57_RS01330	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
E6A57_RS01335	COG0531	amino acid
E6A57_RS01340	COG0561	phosphatase activity
E6A57_RS01345	COG0366	Alpha amylase catalytic
E6A57_RS01350	COG0254	rRNA binding
E6A57_RS01355	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
E6A57_RS01365	COG0736	holo-[acyl-carrier-protein] synthase activity
E6A57_RS01370	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
E6A57_RS01380	COG0039	L-malate dehydrogenase activity
E6A57_RS01385	COG0193	aminoacyl-tRNA hydrolase activity
E6A57_RS01390	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
E6A57_RS01395	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
E6A57_RS01405	COG1185	polyribonucleotide nucleotidyltransferase activity
E6A57_RS01410	COG0037	tRNA processing
E6A57_RS01420	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
E6A57_RS01425	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
E6A57_RS01430	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
E6A57_RS01465	COG1956	GAF domain-containing protein
E6A57_RS01470	COG0542	response to heat
E6A57_RS01475	COG0085	RNA polymerase activity
E6A57_RS01480	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
E6A57_RS01485	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
E6A57_RS01490	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
E6A57_RS01495	COG0049	tRNA binding
E6A57_RS01500	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
E6A57_RS01505	COG0051	transcription antitermination factor activity, RNA binding
E6A57_RS01510	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
E6A57_RS01515	COG0088	Forms part of the polypeptide exit tunnel
E6A57_RS01520	COG0089	rRNA binding
E6A57_RS01525	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
E6A57_RS01535	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
E6A57_RS01540	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
E6A57_RS01545	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
E6A57_RS01550	COG0255	Belongs to the universal ribosomal protein uL29 family
E6A57_RS01555	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
E6A57_RS01560	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
E6A57_RS01565	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
E6A57_RS01570	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
E6A57_RS01575	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
E6A57_RS01580	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
E6A57_RS01585	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
E6A57_RS01590	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
E6A57_RS01595	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
E6A57_RS01600	COG1841	ribosomal large subunit assembly
E6A57_RS01605	COG0200	Binds to the 23S rRNA
E6A57_RS01615	COG0563	adenylate kinase activity
E6A57_RS01620	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
E6A57_RS01630	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
E6A57_RS01635	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
E6A57_RS01640	COG0202	RNA polymerase activity
E6A57_RS01645	COG0203	ribosomal protein L17
E6A57_RS01650	COG1122	ATPase activity
E6A57_RS01655	COG1122	ATPase activity
E6A57_RS01660	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
E6A57_RS01665	COG0101	tRNA pseudouridine synthase activity
E6A57_RS01670	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
E6A57_RS01675	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
E6A57_RS01685	COG4619	ABC transporter
E6A57_RS01690	COG0390	transport system, permease component
E6A57_RS01720	COG1230	cation diffusion facilitator family transporter
E6A57_RS01730	COG0588	phosphoglycerate mutase activity
E6A57_RS01750	COG0756	dUTP diphosphatase activity
E6A57_RS01760	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
E6A57_RS01765	COG0215	cysteine-tRNA ligase activity
E6A57_RS01770	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
E6A57_RS01775	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
E6A57_RS01795	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
E6A57_RS01800	COG0267	Belongs to the bacterial ribosomal protein bL33 family
E6A57_RS01810	COG0250	Participates in transcription elongation, termination and antitermination
E6A57_RS01815	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
E6A57_RS01820	COG0081	regulation of translation
E6A57_RS01825	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
E6A57_RS01830	COG0573	inorganic phosphate transmembrane transporter activity
E6A57_RS01835	COG0581	inorganic phosphate transmembrane transporter activity
E6A57_RS01840	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
E6A57_RS01845	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
E6A57_RS01850	COG0704	Plays a role in the regulation of phosphate uptake
E6A57_RS01865	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
E6A57_RS01870	COG0222	ribosome binding
E6A57_RS01880	COG2813	Specifically methylates the guanine in position
E6A57_RS01890	COG0590	tRNA wobble adenosine to inosine editing
E6A57_RS01900	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
E6A57_RS01915	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
E6A57_RS01920	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
E6A57_RS01930	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
E6A57_RS01935	COG3870	Protein conserved in bacteria
E6A57_RS01960	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
E6A57_RS01965	COG1214	PFAM Peptidase M22, glycoprotease
E6A57_RS01975	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
E6A57_RS01990	COG0488	(ABC) transporter
E6A57_RS01995	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
E6A57_RS02010	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
E6A57_RS02010	COG2190	(PTS) system
E6A57_RS02010	COG1263	PTS System
E6A57_RS02025	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
E6A57_RS02030	COG0459	protein refolding
E6A57_RS02035	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
E6A57_RS02040	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
E6A57_RS02045	COG0632	four-way junction helicase activity
E6A57_RS02050	COG2255	four-way junction helicase activity
E6A57_RS02060	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
E6A57_RS02065	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
E6A57_RS02070	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
E6A57_RS02075	COG0513	Belongs to the DEAD box helicase family
E6A57_RS02080	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
E6A57_RS02085	COG4472	Bacterial protein of unknown function (DUF965)
E6A57_RS02090	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
E6A57_RS02095	COG3906	Belongs to the UPF0473 family
E6A57_RS02100	COG1193	negative regulation of DNA recombination
E6A57_RS02105	COG3118	belongs to the thioredoxin family
E6A57_RS02115	COG1719	4-vinyl reductase, 4VR
E6A57_RS02120	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
E6A57_RS02125	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
E6A57_RS02130	COG0668	transmembrane transport
E6A57_RS02145	COG0006	proline dipeptidase activity
E6A57_RS02165	COG0737	Belongs to the 5'-nucleotidase family
E6A57_RS02175	COG0647	UMP catabolic process
E6A57_RS02185	COG0586	Pfam SNARE associated Golgi protein
E6A57_RS02190	COG0492	ferredoxin-NADP+ reductase activity
E6A57_RS02355	COG0438	transferase activity, transferring glycosyl groups
E6A57_RS02360	COG0438	transferase activity, transferring glycosyl groups
E6A57_RS02370	COG1368	sulfuric ester hydrolase activity
E6A57_RS02375	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
E6A57_RS02380	COG0557	exoribonuclease II activity
E6A57_RS02385	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
E6A57_RS02445	COG3715	PTS system
E6A57_RS02450	COG3716	PTS system mannose fructose sorbose family IID component
E6A57_RS02460	COG0583	DNA-binding transcription factor activity
E6A57_RS02465	COG0110	maltose O-acetyltransferase activity
E6A57_RS02470	COG1113	amino acid transport
E6A57_RS02475	COG1454	alcohol dehydrogenase
E6A57_RS02475	COG1012	belongs to the aldehyde dehydrogenase family
E6A57_RS02480	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
E6A57_RS02495	COG0494	nUDIX hydrolase
E6A57_RS02515	COG1205	dead DEAH box helicase
E6A57_RS02515	COG1111	helicase
E6A57_RS02525	COG0778	Nitroreductase
E6A57_RS02540	COG0110	maltose O-acetyltransferase activity
E6A57_RS02570	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
E6A57_RS02570	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
E6A57_RS02585	COG0588	phosphoglycerate mutase activity
E6A57_RS02605	COG1609	Transcriptional regulator
E6A57_RS02615	COG1175	transmembrane transport
E6A57_RS02620	COG0395	ABC-type sugar transport system, permease component
E6A57_RS02625	COG1621	beta-fructofuranosidase activity
E6A57_RS02630	COG3842	ATPase activity
E6A57_RS02635	COG0366	Alpha amylase catalytic
E6A57_RS02645	COG0436	Aminotransferase
E6A57_RS02650	COG0673	inositol 2-dehydrogenase activity
E6A57_RS02655	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
E6A57_RS02660	COG1737	Transcriptional regulator
E6A57_RS02670	COG0446	pyridine nucleotide-disulphide oxidoreductase
E6A57_RS02685	COG4166	transmembrane transport
E6A57_RS02705	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
E6A57_RS02715	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
E6A57_RS02745	COG3091	SprT-like family
E6A57_RS02755	COG1705	Flagellar rod assembly protein muramidase FlgJ
E6A57_RS02765	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
E6A57_RS02770	COG4851	CamS sex pheromone cAM373 precursor
E6A57_RS02775	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
E6A57_RS02780	COG0154	amidase activity
E6A57_RS02785	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
E6A57_RS02790	COG1597	lipid kinase activity
E6A57_RS02820	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
E6A57_RS02850	COG2814	Major facilitator Superfamily
E6A57_RS02860	COG4716	Myosin-crossreactive antigen
E6A57_RS02870	COG0656	L-ascorbic acid biosynthetic process
E6A57_RS02895	COG0477	Major facilitator Superfamily
E6A57_RS02920	COG0488	(ABC) transporter
E6A57_RS02925	COG4989	oxidoreductase activity
E6A57_RS02935	COG0531	amino acid
E6A57_RS02940	COG0519	Catalyzes the synthesis of GMP from XMP
E6A57_RS02945	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
E6A57_RS02955	COG1132	(ABC) transporter
E6A57_RS02960	COG1132	(ABC) transporter
E6A57_RS02975	COG0572	uridine kinase
E6A57_RS02985	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
E6A57_RS02990	COG0765	amino acid transport
E6A57_RS02995	COG0765	amino acid transport
E6A57_RS03030	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
E6A57_RS03035	COG3158	transport of potassium into the cell
E6A57_RS03045	COG2188	Transcriptional regulator
E6A57_RS03050	COG0561	phosphatase activity
E6A57_RS03065	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
E6A57_RS03075	COG0561	phosphatase activity
E6A57_RS03080	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
E6A57_RS03080	COG1263	PTS System
E6A57_RS03085	COG1737	Transcriptional regulator
E6A57_RS03095	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
E6A57_RS03095	COG1263	PTS System
E6A57_RS03095	COG2190	(PTS) system
E6A57_RS03110	COG1253	flavin adenine dinucleotide binding
E6A57_RS03120	COG1053	succinate dehydrogenase
E6A57_RS03130	COG1053	succinate dehydrogenase
E6A57_RS03130	COG3976	FMN-binding domain protein
E6A57_RS03135	COG0531	amino acid
E6A57_RS03150	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
E6A57_RS03165	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
E6A57_RS03175	COG0716	FMN binding
E6A57_RS03180	COG0024	Methionine aminopeptidase
E6A57_RS03185	COG1295	ribonuclease BN
E6A57_RS03190	COG1210	Utp--glucose-1-phosphate uridylyltransferase
E6A57_RS03195	COG0183	Belongs to the thiolase family
E6A57_RS03205	COG3425	synthase
E6A57_RS03220	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
E6A57_RS03245	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
E6A57_RS03255	COG1132	(ABC) transporter
E6A57_RS03305	COG0542	response to heat
E6A57_RS03315	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
E6A57_RS03325	COG1393	Belongs to the ArsC family
E6A57_RS03330	COG4862	establishment of competence for transformation
E6A57_RS03350	COG2357	RelA SpoT domain protein
E6A57_RS03355	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
E6A57_RS03360	COG0564	pseudouridine synthase activity
E6A57_RS03375	COG2706	6-phosphogluconolactonase activity
E6A57_RS03385	COG0628	permease
E6A57_RS03400	COG1674	ftsk spoiiie
E6A57_RS03400	COG1280	lysine exporter protein (LysE YggA)
E6A57_RS03410	COG0612	Peptidase, M16
E6A57_RS03415	COG1028	Short-chain dehydrogenase reductase Sdr
E6A57_RS03420	COG1426	Protein conserved in bacteria
E6A57_RS03425	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
E6A57_RS03430	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
E6A57_RS03435	COG1418	mRNA catabolic process
E6A57_RS03440	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
E6A57_RS03445	COG1739	Uncharacterized protein family UPF0029
E6A57_RS03450	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
E6A57_RS03465	COG0653	protein targeting
E6A57_RS03480	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
E6A57_RS03485	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
E6A57_RS03490	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
E6A57_RS03495	COG0492	ferredoxin-NADP+ reductase activity
E6A57_RS03500	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
E6A57_RS03505	COG0556	nucleotide-excision repair
E6A57_RS03510	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
E6A57_RS03520	COG1660	Displays ATPase and GTPase activities
E6A57_RS03525	COG0391	Required for morphogenesis under gluconeogenic growth conditions
E6A57_RS03530	COG1481	regulation of sporulation
E6A57_RS03535	COG0740	serine-type endopeptidase activity
E6A57_RS03545	COG4619	ABC transporter
E6A57_RS03550	COG0390	transport system, permease component
E6A57_RS03560	COG2814	Major facilitator Superfamily
E6A57_RS03575	COG0531	amino acid
E6A57_RS03590	COG2390	Transcriptional regulator
E6A57_RS03600	COG0126	phosphoglycerate kinase activity
E6A57_RS03605	COG0149	triose-phosphate isomerase activity
E6A57_RS03615	COG0561	phosphatase activity
E6A57_RS03620	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
E6A57_RS03625	COG0280	phosphate acetyltransferase
E6A57_RS03630	COG0802	atpase or kinase
E6A57_RS03640	COG0812	UDP-N-acetylmuramate dehydrogenase activity
E6A57_RS03645	COG3842	ATPase activity
E6A57_RS03650	COG1176	ABC-type spermidine putrescine transport system, permease component I
E6A57_RS03670	COG4856	YbbR-like protein
E6A57_RS03675	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
E6A57_RS03680	COG0561	phosphatase activity
E6A57_RS03695	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
E6A57_RS03700	COG1929	Belongs to the glycerate kinase type-1 family
E6A57_RS03710	COG2190	(PTS) system
E6A57_RS03710	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
E6A57_RS03710	COG1263	PTS System
E6A57_RS03725	COG0531	amino acid
E6A57_RS03730	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
E6A57_RS03745	COG0217	transcriptional regulatory protein
E6A57_RS03750	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
E6A57_RS03780	COG0827	DNA restriction-modification system
E6A57_RS03800	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
E6A57_RS03805	COG1482	cell wall glycoprotein biosynthetic process
E6A57_RS03815	COG0745	RESPONSE REGULATOR receiver
E6A57_RS03820	COG3850	Histidine kinase
E6A57_RS03820	COG5002	protein histidine kinase activity
E6A57_RS03825	COG1368	sulfuric ester hydrolase activity
E6A57_RS03835	COG0166	Belongs to the GPI family
E6A57_RS03840	COG0477	Major facilitator Superfamily
E6A57_RS03845	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
E6A57_RS03860	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
E6A57_RS03865	COG1435	thymidine kinase activity
E6A57_RS03870	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
E6A57_RS03875	COG2890	protein-(glutamine-N5) methyltransferase activity
E6A57_RS03880	COG0009	L-threonylcarbamoyladenylate synthase
E6A57_RS03885	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
E6A57_RS03890	COG0356	it plays a direct role in the translocation of protons across the membrane
E6A57_RS03895	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
E6A57_RS03900	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
E6A57_RS03905	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
E6A57_RS03910	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
E6A57_RS03915	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
E6A57_RS03920	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
E6A57_RS03925	COG0355	proton-transporting ATP synthase activity, rotational mechanism
E6A57_RS03940	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
E6A57_RS03950	COG0772	Belongs to the SEDS family
E6A57_RS03990	COG0589	response to stress
E6A57_RS04000	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
E6A57_RS04010	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
E6A57_RS04015	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
E6A57_RS04020	COG1104	cysteine desulfurase activity
E6A57_RS04025	COG0301	tRNA thio-modification
E6A57_RS04090	COG1187	pseudouridine synthase activity
E6A57_RS04105	COG0463	Glycosyl transferase, family 2
E6A57_RS04125	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
E6A57_RS04160	COG0431	NADPH-dependent FMN reductase
E6A57_RS04160	COG1053	succinate dehydrogenase
E6A57_RS04160	COG3976	FMN-binding domain protein
E6A57_RS04185	COG0525	valine-tRNA ligase activity
E6A57_RS04195	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
E6A57_RS04200	COG2003	Belongs to the UPF0758 family
E6A57_RS04205	COG1077	Cell shape determining protein MreB Mrl
E6A57_RS04210	COG1792	Involved in formation and maintenance of cell shape
E6A57_RS04230	COG2001	Belongs to the MraZ family
E6A57_RS04235	COG0275	rRNA processing
E6A57_RS04250	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
E6A57_RS04255	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
E6A57_RS04260	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
E6A57_RS04265	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
E6A57_RS04275	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
E6A57_RS04280	COG1799	cell septum assembly
E6A57_RS04300	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
E6A57_RS04305	COG1278	Cold shock
E6A57_RS04310	COG0494	nUDIX hydrolase
E6A57_RS04325	COG1104	cysteine desulfurase activity
E6A57_RS04335	COG0482	sulfurtransferase activity
E6A57_RS04340	COG0406	alpha-ribazole phosphatase activity
E6A57_RS04350	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
E6A57_RS04360	COG1597	lipid kinase activity
E6A57_RS04380	COG0242	peptide deformylase activity
E6A57_RS04390	COG0772	Belongs to the SEDS family
E6A57_RS04395	COG4471	UPF0298 protein
E6A57_RS04400	COG0742	ribosomal rna small subunit methyltransferase
E6A57_RS04405	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
E6A57_RS04410	COG3480	Lon protease (S16) C-terminal proteolytic domain
E6A57_RS04415	COG1555	photosystem II stabilization
E6A57_RS04420	COG0658	competence protein
E6A57_RS04420	COG2333	competence protein COMEC
E6A57_RS04425	COG1466	dna polymerase III delta subunit
E6A57_RS04430	COG0268	Binds directly to 16S ribosomal RNA
E6A57_RS04435	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
E6A57_RS04450	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
E6A57_RS04455	COG0544	peptidyl-prolyl cis-trans isomerase activity
E6A57_RS04460	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
E6A57_RS04465	COG0218	Necessary for normal cell division and for the maintenance of normal septation
E6A57_RS04475	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
E6A57_RS04480	COG0527	aspartate kinase activity
E6A57_RS04485	COG0019	diaminopimelate decarboxylase activity
E6A57_RS04490	COG2171	N-acyltransferase activity
E6A57_RS04495	COG1473	amidohydrolase
E6A57_RS04500	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
E6A57_RS04505	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
E6A57_RS04510	COG0436	Aminotransferase
E6A57_RS04515	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
E6A57_RS04520	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
E6A57_RS04530	COG1053	succinate dehydrogenase
E6A57_RS04530	COG0431	NADPH-dependent FMN reductase
E6A57_RS04530	COG3976	FMN-binding domain protein
E6A57_RS04540	COG1957	nucleoside hydrolase
E6A57_RS04550	COG2723	6-phospho-beta-galactosidase activity
E6A57_RS04555	COG2188	Transcriptional regulator
E6A57_RS04560	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
E6A57_RS04565	COG1447	Phosphotransferase system cellobiose-specific component IIA
E6A57_RS04575	COG2723	6-phospho-beta-galactosidase activity
E6A57_RS04580	COG2188	Transcriptional regulator
E6A57_RS04590	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
E6A57_RS04595	COG2723	6-phospho-beta-galactosidase activity
E6A57_RS04615	COG0148	phosphopyruvate hydratase activity
E6A57_RS04630	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
E6A57_RS04640	COG2855	membrane
E6A57_RS04645	COG0783	Belongs to the Dps family
E6A57_RS04660	COG1011	Hydrolase
E6A57_RS04670	COG0519	Catalyzes the synthesis of GMP from XMP
E6A57_RS04700	COG1215	transferase activity, transferring glycosyl groups
E6A57_RS04720	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
E6A57_RS04725	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
E6A57_RS04725	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
E6A57_RS04730	COG0307	riboflavin synthase, alpha
E6A57_RS04735	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
E6A57_RS04735	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
E6A57_RS04740	COG1028	Short-chain dehydrogenase reductase Sdr
E6A57_RS04755	COG0583	DNA-binding transcription factor activity
E6A57_RS04780	COG1051	belongs to the nudix hydrolase family
E6A57_RS04785	COG1114	Component of the transport system for branched-chain amino acids
E6A57_RS04795	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
E6A57_RS04845	COG1132	(ABC) transporter
E6A57_RS04850	COG1113	amino acid transport
E6A57_RS04855	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
E6A57_RS04860	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
E6A57_RS04865	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
E6A57_RS04880	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
E6A57_RS04885	COG2011	ABC-type metal ion transport system permease component
E6A57_RS04890	COG0114	fumarate hydratase activity
E6A57_RS04895	COG1053	succinate dehydrogenase
E6A57_RS04900	COG0039	L-malate dehydrogenase activity
E6A57_RS04905	COG3579	cysteine-type endopeptidase activity
E6A57_RS04910	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
E6A57_RS04915	COG0471	metal ion transport
E6A57_RS04920	COG2267	carboxylic ester hydrolase activity
E6A57_RS04930	COG3052	prosthetic group binding
E6A57_RS04945	COG2707	UPF0756 membrane protein
E6A57_RS04955	COG1122	ATPase activity
E6A57_RS04960	COG4720	Psort location CytoplasmicMembrane, score
E6A57_RS04985	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
E6A57_RS04990	COG2264	protein methyltransferase activity
E6A57_RS05000	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
E6A57_RS05005	COG1490	D-aminoacyl-tRNA deacylase activity
E6A57_RS05010	COG0124	histidyl-tRNA synthetase
E6A57_RS05015	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
E6A57_RS05020	COG0436	Aminotransferase
E6A57_RS05035	COG0656	L-ascorbic acid biosynthetic process
E6A57_RS05040	COG0561	phosphatase activity
E6A57_RS05045	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
E6A57_RS05050	COG0531	amino acid
E6A57_RS05055	COG0586	Pfam SNARE associated Golgi protein
E6A57_RS05060	COG0322	excinuclease ABC activity
E6A57_RS05065	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
E6A57_RS05070	COG2755	lipolytic protein G-D-S-L family
E6A57_RS05070	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
E6A57_RS05075	COG1234	tRNA 3'-trailer cleavage
E6A57_RS05080	COG0300	oxidoreductase activity
E6A57_RS05090	COG0333	Belongs to the bacterial ribosomal protein bL32 family
E6A57_RS05095	COG0737	Belongs to the 5'-nucleotidase family
E6A57_RS05105	COG0587	DNA-directed DNA polymerase activity
E6A57_RS05110	COG0205	6-phosphofructokinase activity
E6A57_RS05120	COG2996	Protein conserved in bacteria
E6A57_RS05135	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
E6A57_RS05140	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
E6A57_RS05145	COG1187	pseudouridine synthase activity
E6A57_RS05150	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
E6A57_RS05160	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
E6A57_RS05165	COG0539	negative regulation of cytoplasmic translation
E6A57_RS05170	COG1160	GTP binding
E6A57_RS05190	COG1132	(ABC) transporter
E6A57_RS05230	COG2365	Tyrosine phosphatase family
E6A57_RS05265	COG0295	cytidine deaminase activity
E6A57_RS05295	COG0531	amino acid
E6A57_RS05305	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
E6A57_RS05310	COG0617	tRNA 3'-terminal CCA addition
E6A57_RS05315	COG1272	protein, Hemolysin III
E6A57_RS05320	COG1307	EDD domain protein, DegV family
E6A57_RS05325	COG4479	Belongs to the UPF0346 family
E6A57_RS05335	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
E6A57_RS05340	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
E6A57_RS05345	COG0758	DNA mediated transformation
E6A57_RS05350	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
E6A57_RS05355	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
E6A57_RS05360	COG4974	Belongs to the 'phage' integrase family
E6A57_RS05370	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
E6A57_RS05395	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
E6A57_RS05400	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
E6A57_RS05410	COG0833	amino acid
E6A57_RS05425	COG0531	amino acid
E6A57_RS05435	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
E6A57_RS05440	COG0514	ATP-dependent DNA helicase (RecQ)
E6A57_RS05480	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
E6A57_RS05485	COG2040	homocysteine
E6A57_RS05510	COG0110	maltose O-acetyltransferase activity
E6A57_RS05540	COG2195	Cleaves the N-terminal amino acid of tripeptides
E6A57_RS05545	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
E6A57_RS05550	COG1393	Belongs to the ArsC family
E6A57_RS05565	COG1653	transport
E6A57_RS05685	COG2759	Belongs to the formate--tetrahydrofolate ligase family
E6A57_RS05695	COG0564	pseudouridine synthase activity
E6A57_RS05700	COG0505	Belongs to the CarA family
E6A57_RS05705	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
E6A57_RS05720	COG1307	EDD domain protein, DegV family
E6A57_RS05725	COG1193	negative regulation of DNA recombination
E6A57_RS05770	COG1227	inorganic diphosphatase activity
E6A57_RS05775	COG0583	DNA-binding transcription factor activity
E6A57_RS05785	COG0187	DNA topoisomerase II activity
E6A57_RS05790	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
E6A57_RS05805	COG1335	isochorismatase
E6A57_RS05835	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
E6A57_RS05850	COG0116	Belongs to the methyltransferase superfamily
E6A57_RS05860	COG3599	regulation of cell shape
E6A57_RS05865	COG4474	Belongs to the UPF0398 family
E6A57_RS05870	COG3331	DNA recombination
E6A57_RS05875	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
E6A57_RS05880	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
E6A57_RS05890	COG0017	Asparaginyl-tRNA synthetase
E6A57_RS05905	COG1074	ATP-dependent DNA helicase activity
E6A57_RS05910	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
E6A57_RS05930	COG1304	FMN binding
E6A57_RS05935	COG0561	phosphatase activity
E6A57_RS05980	COG1131	(ABC) transporter
E6A57_RS05985	COG1725	Transcriptional regulator
E6A57_RS05990	COG2195	Cleaves the N-terminal amino acid of tripeptides
E6A57_RS05995	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
E6A57_RS06000	COG2384	SAM-dependent methyltransferase
E6A57_RS06015	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
E6A57_RS06020	COG0358	DNA primase activity
E6A57_RS06025	COG0751	glycine-tRNA ligase activity
E6A57_RS06030	COG0752	glycyl-tRNA synthetase alpha subunit
E6A57_RS06035	COG1381	Involved in DNA repair and RecF pathway recombination
E6A57_RS06040	COG0675	Transposase, IS605 OrfB family
E6A57_RS06050	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
E6A57_RS06055	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
E6A57_RS06060	COG1702	phosphate starvation-inducible protein PhoH
E6A57_RS06070	COG0828	Belongs to the bacterial ribosomal protein bS21 family
E6A57_RS06075	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
E6A57_RS06125	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
E6A57_RS06135	COG2217	Heavy metal translocating P-type atpase
E6A57_RS06155	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
E6A57_RS06160	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
E6A57_RS06350	COG0083	homoserine kinase activity
E6A57_RS06365	COG0527	aspartate kinase activity
E6A57_RS06395	COG1132	(ABC) transporter
E6A57_RS06435	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
E6A57_RS06445	COG2235	arginine
E6A57_RS06450	COG0583	DNA-binding transcription factor activity
E6A57_RS06475	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
E6A57_RS06485	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
E6A57_RS06490	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
E6A57_RS06490	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
E6A57_RS06495	COG3764	Sortase (surface protein transpeptidase)
E6A57_RS06500	COG0481	GTPase activity
E6A57_RS06510	COG0484	heat shock protein binding
E6A57_RS06515	COG0443	Heat shock 70 kDa protein
E6A57_RS06520	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
E6A57_RS06525	COG1420	regulation of RNA biosynthetic process
E6A57_RS06530	COG0196	riboflavin kinase activity
E6A57_RS06535	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
E6A57_RS06540	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
E6A57_RS06545	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
E6A57_RS06555	COG2740	Nucleic-acid-binding protein implicated in transcription termination
E6A57_RS06560	COG0195	Participates in both transcription termination and antitermination
E6A57_RS06565	COG0779	Required for maturation of 30S ribosomal subunits
E6A57_RS06575	COG0442	prolyl-tRNA aminoacylation
E6A57_RS06580	COG0750	zinc metalloprotease
E6A57_RS06585	COG4589	Belongs to the CDS family
E6A57_RS06590	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
E6A57_RS06595	COG0233	cytoplasmic translational termination
E6A57_RS06600	COG0528	UMP kinase activity
E6A57_RS06605	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
E6A57_RS06610	COG0052	Belongs to the universal ribosomal protein uS2 family
E6A57_RS06615	COG2827	Endonuclease containing a URI domain
E6A57_RS06620	COG0204	Acyl-transferase
E6A57_RS06625	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
E6A57_RS06630	COG3590	peptidase
E6A57_RS06635	COG1132	(ABC) transporter
E6A57_RS06640	COG1132	(ABC) transporter
E6A57_RS06645	COG3763	UPF0154 protein
E6A57_RS06650	COG4224	UPF0291 protein
E6A57_RS06655	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
E6A57_RS06675	COG0335	large ribosomal subunit rRNA binding
E6A57_RS06680	COG0336	Belongs to the RNA methyltransferase TrmD family
E6A57_RS06685	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
E6A57_RS06690	COG0228	four-way junction DNA binding
E6A57_RS06695	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
E6A57_RS06700	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
E6A57_RS06705	COG0531	amino acid
E6A57_RS06715	COG1136	(ABC) transporter
E6A57_RS06730	COG0552	protein localization to endoplasmic reticulum
E6A57_RS06735	COG1196	nuclear chromosome segregation
E6A57_RS06740	COG0571	ribonuclease III activity
E6A57_RS06765	COG0601	transmembrane transport
E6A57_RS06770	COG4608	Belongs to the ABC transporter superfamily
E6A57_RS06780	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
E6A57_RS06785	COG0416	fatty acid biosynthetic process
E6A57_RS06790	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
E6A57_RS06795	COG1461	Dihydroxyacetone kinase
E6A57_RS06805	COG0227	Belongs to the bacterial ribosomal protein bL28 family
E6A57_RS06855	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
E6A57_RS06860	COG1162	GTPase activity
E6A57_RS06865	COG2815	serine threonine protein kinase
E6A57_RS06865	COG0515	serine threonine protein kinase
E6A57_RS06875	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
E6A57_RS06875	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
E6A57_RS06880	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
E6A57_RS06885	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
E6A57_RS06890	COG1758	RNA polymerase activity
E6A57_RS06895	COG0194	GDP metabolic process
E6A57_RS06905	COG0497	DNA recombination
E6A57_RS06910	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
E6A57_RS06920	COG1722	exodeoxyribonuclease VII activity
E6A57_RS06925	COG1570	exodeoxyribonuclease VII activity
E6A57_RS06930	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
E6A57_RS06940	COG1302	Protein conserved in bacteria
E6A57_RS06945	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
E6A57_RS06950	COG0006	proline dipeptidase activity
E6A57_RS06955	COG0211	Belongs to the bacterial ribosomal protein bL27 family
E6A57_RS06960	COG0261	This protein binds to 23S rRNA in the presence of protein L20
E6A57_RS06985	COG1942	4-Oxalocrotonate Tautomerase
E6A57_RS07015	COG1393	Belongs to the ArsC family
E6A57_RS07020	COG1132	(ABC) transporter
E6A57_RS07025	COG1132	(ABC) transporter
E6A57_RS07030	COG0561	phosphatase activity
E6A57_RS07050	COG2936	dipeptidyl-peptidase activity
E6A57_RS07075	COG4975	Glucose uptake
E6A57_RS07090	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
E6A57_RS07095	COG0505	Belongs to the CarA family
E6A57_RS07100	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
E6A57_RS07105	COG0540	Belongs to the ATCase OTCase family
E6A57_RS07115	COG0167	dihydroorotate dehydrogenase activity
E6A57_RS07120	COG0284	orotidine-5'-phosphate decarboxylase activity
E6A57_RS07125	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
E6A57_RS07145	COG1760	l-serine dehydratase
E6A57_RS07150	COG1760	l-serine dehydratase
E6A57_RS07155	COG2151	metal-sulfur cluster biosynthetic enzyme
E6A57_RS07165	COG1304	FMN binding
E6A57_RS07175	COG0531	amino acid
E6A57_RS07215	COG5002	protein histidine kinase activity
E6A57_RS07220	COG0745	RESPONSE REGULATOR receiver
E6A57_RS07225	COG2357	RelA SpoT domain protein
E6A57_RS07230	COG0366	Alpha amylase catalytic
E6A57_RS07235	COG3345	alpha-galactosidase
E6A57_RS07255	COG2017	converts alpha-aldose to the beta-anomer
E6A57_RS07260	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
E6A57_RS07265	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
E6A57_RS07275	COG1874	Beta-galactosidase
E6A57_RS07280	COG2211	Major facilitator Superfamily
E6A57_RS07280	COG2190	(PTS) system
E6A57_RS07285	COG1609	Transcriptional regulator
E6A57_RS07290	COG3250	beta-galactosidase activity
E6A57_RS07295	COG3250	beta-galactosidase activity
E6A57_RS07300	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
E6A57_RS07305	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
E6A57_RS07310	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
E6A57_RS07315	COG1461	Dihydroxyacetone kinase
E6A57_RS07320	COG2376	Dihydroxyacetone kinase
E6A57_RS07330	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
E6A57_RS07415	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
E6A57_RS07420	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
E6A57_RS07435	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
E6A57_RS07440	COG0267	Belongs to the bacterial ribosomal protein bL33 family
E6A57_RS07445	COG0768	penicillin binding
E6A57_RS07455	COG2971	BadF BadG BcrA BcrD
E6A57_RS07475	COG4604	ABC transporter, ATP-binding protein
E6A57_RS07495	COG4166	transmembrane transport
E6A57_RS07500	COG0561	phosphatase activity
E6A57_RS07520	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
E6A57_RS07525	COG0072	phenylalanine-tRNA ligase activity
E6A57_RS07530	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
E6A57_RS07535	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
E6A57_RS07540	COG1126	abc transporter atp-binding protein
E6A57_RS07545	COG0765	amino acid transport
E6A57_RS07550	COG0765	amino acid transport
E6A57_RS07555	COG1733	regulation of RNA biosynthetic process
E6A57_RS07560	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
E6A57_RS07565	COG1254	Belongs to the acylphosphatase family
E6A57_RS07570	COG0706	membrane insertase activity
E6A57_RS07595	COG5002	protein histidine kinase activity
E6A57_RS07600	COG0745	RESPONSE REGULATOR receiver
E6A57_RS07610	COG1323	Belongs to the UPF0348 family
E6A57_RS07615	COG0799	negative regulation of ribosome biogenesis
E6A57_RS07620	COG1713	HD superfamily hydrolase involved in NAD metabolism
E6A57_RS07625	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
E6A57_RS07630	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
E6A57_RS07635	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
E6A57_RS07645	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
E6A57_RS07650	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
E6A57_RS07655	COG0291	Belongs to the bacterial ribosomal protein bL35 family
E6A57_RS07660	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
E6A57_RS07675	COG1131	(ABC) transporter
E6A57_RS07690	COG1733	regulation of RNA biosynthetic process
E6A57_RS07710	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
E6A57_RS07715	COG1484	DNA-dependent DNA replication
E6A57_RS07725	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
E6A57_RS07730	COG0237	dephospho-CoA kinase activity
E6A57_RS07735	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
E6A57_RS07740	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
E6A57_RS07740	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
E6A57_RS07755	COG0732	type I restriction modification DNA specificity domain
E6A57_RS07830	COG0534	Mate efflux family protein
E6A57_RS07835	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
E6A57_RS07840	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
E6A57_RS07845	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
E6A57_RS07855	COG0220	tRNA (guanine-N7-)-methyltransferase activity
E6A57_RS07865	COG1131	(ABC) transporter
E6A57_RS07870	COG0537	adenosine 5'-monophosphoramidase activity
E6A57_RS07880	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
E6A57_RS07915	COG3481	metal-dependent phosphohydrolase, HD sub domain
E6A57_RS07930	COG3679	Belongs to the UPF0342 family
E6A57_RS07935	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
E6A57_RS07940	COG0564	pseudouridine synthase activity
E6A57_RS07945	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
E6A57_RS07945	COG0574	Belongs to the PEP-utilizing enzyme family
E6A57_RS07950	COG0588	phosphoglycerate mutase activity
E6A57_RS07955	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
E6A57_RS07965	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
E6A57_RS08005	COG1051	belongs to the nudix hydrolase family
E6A57_RS08015	COG0018	arginyl-trna synthetase
E6A57_RS08020	COG1376	ErfK ybiS ycfS ynhG family protein
E6A57_RS08025	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
E6A57_RS08030	COG1686	Belongs to the peptidase S11 family
E6A57_RS08040	COG1983	PspC domain protein
E6A57_RS08045	COG2244	polysaccharide biosynthetic process
E6A57_RS08050	COG0495	leucyl-tRNA aminoacylation
E6A57_RS08055	COG0671	phosphoesterase, PA-phosphatase related
E6A57_RS08060	COG0583	DNA-binding transcription factor activity
E6A57_RS08085	COG0142	geranyltranstransferase activity
E6A57_RS08090	COG2226	methyltransferase
E6A57_RS08095	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
E6A57_RS08100	COG4988	ABC transporter
E6A57_RS08105	COG1294	oxidase, subunit
E6A57_RS08110	COG1271	oxidase subunit
E6A57_RS08130	COG1263	PTS System
E6A57_RS08130	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
E6A57_RS08135	COG0477	Major facilitator Superfamily
E6A57_RS08140	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
E6A57_RS08210	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
E6A57_RS08215	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
E6A57_RS08220	COG0398	Pfam SNARE associated Golgi protein
E6A57_RS08240	COG1012	belongs to the aldehyde dehydrogenase family
E6A57_RS08250	COG2409	Drug exporters of the RND superfamily
E6A57_RS08250	COG1033	growth of symbiont in host cell
E6A57_RS08285	COG1175	transmembrane transport
E6A57_RS08305	COG2176	DNA-directed DNA polymerase activity
E6A57_RS08340	COG1132	(ABC) transporter
E6A57_RS08345	COG2267	carboxylic ester hydrolase activity
E6A57_RS08350	COG0745	RESPONSE REGULATOR receiver
E6A57_RS08355	COG5002	protein histidine kinase activity
E6A57_RS08375	COG1846	Transcriptional regulator
E6A57_RS08380	COG1132	(ABC) transporter
E6A57_RS08385	COG4166	transmembrane transport
E6A57_RS08400	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
E6A57_RS08405	COG1072	(Pantothenic acid kinase))
E6A57_RS08415	COG2153	protein acetylation
E6A57_RS08420	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
E6A57_RS08425	COG1126	abc transporter atp-binding protein
E6A57_RS08430	COG0765	amino acid transport
E6A57_RS08435	COG3973	AAA domain
E6A57_RS08445	COG0588	phosphoglycerate mutase activity
E6A57_RS08475	COG0252	asparaginase activity
E6A57_RS08525	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
E6A57_RS08600	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
E6A57_RS08605	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
E6A57_RS08615	COG1091	dTDP-4-dehydrorhamnose reductase activity
E6A57_RS08620	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
E6A57_RS08630	COG1088	dTDP-glucose 4,6-dehydratase activity
E6A57_RS08635	COG2226	methyltransferase
E6A57_RS08720	COG1215	transferase activity, transferring glycosyl groups
E6A57_RS08745	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
E6A57_RS08750	COG4464	protein tyrosine phosphatase activity
E6A57_RS08755	COG0489	protein tyrosine kinase activity
E6A57_RS08765	COG1316	TRANSCRIPTIONal
E6A57_RS08770	COG3077	Addiction module antitoxin, RelB DinJ family
E6A57_RS08775	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
E6A57_RS08790	COG0791	NLP P60 protein
E6A57_RS08795	COG0791	NLP P60 protein
E6A57_RS08800	COG0791	NLP P60 protein
E6A57_RS08805	COG0194	GDP metabolic process
E6A57_RS08830	COG1780	Probably involved in ribonucleotide reductase function
E6A57_RS08850	COG4990	cell redox homeostasis
E6A57_RS08865	COG0488	(ABC) transporter
E6A57_RS08875	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
E6A57_RS08885	COG1811	Na channel or pump
E6A57_RS08890	COG1316	TRANSCRIPTIONal
E6A57_RS08895	COG1164	Oligoendopeptidase f
E6A57_RS08930	COG1121	(ABC) transporter
E6A57_RS08940	COG0640	Transcriptional regulator
E6A57_RS08945	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
E6A57_RS08945	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
E6A57_RS08945	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
E6A57_RS08950	COG1105	Belongs to the carbohydrate kinase PfkB family
E6A57_RS08955	COG1420	regulation of RNA biosynthetic process
E6A57_RS08960	COG1668	transmembrane transport
E6A57_RS08965	COG4152	abc transporter atp-binding protein
E6A57_RS08985	COG3655	Transcriptional regulator
E6A57_RS09035	COG3279	Response regulator of the LytR AlgR family
E6A57_RS09075	COG0277	FAD linked oxidase domain protein
E6A57_RS09100	COG1794	racemase activity, acting on amino acids and derivatives
E6A57_RS09105	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
E6A57_RS09130	COG1132	(ABC) transporter
E6A57_RS09135	COG1132	(ABC) transporter
E6A57_RS09145	COG0012	GTP binding
E6A57_RS09150	COG4481	Protein conserved in bacteria
E6A57_RS09155	COG1475	DNA binding
E6A57_RS09160	COG1192	Involved in chromosome partitioning
E6A57_RS09165	COG1475	DNA binding
E6A57_RS09170	COG0357	Ribosomal RNA small subunit methyltransferase G
E6A57_RS09195	COG0431	NADPH-dependent FMN reductase
E6A57_RS09200	COG0431	NADPH-dependent FMN reductase
E6A57_RS09220	COG1136	(ABC) transporter
E6A57_RS09235	COG0406	alpha-ribazole phosphatase activity
E6A57_RS09245	COG3022	response to hydroperoxide
E6A57_RS09255	COG3104	oligopeptide transport
E6A57_RS09270	COG0675	Transposase, IS605 OrfB family
E6A57_RS09290	COG3104	oligopeptide transport
E6A57_RS09295	COG0308	aminopeptidase N
E6A57_RS09350	COG3833	ABC-type maltose transport systems, permease component
E6A57_RS09355	COG1175	transmembrane transport
E6A57_RS09365	COG3842	ATPase activity
E6A57_RS09370	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
E6A57_RS09385	COG0366	Alpha amylase catalytic
E6A57_RS09395	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
E6A57_RS09400	COG1609	Transcriptional regulator
E6A57_RS09410	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
E6A57_RS09415	COG0351	phosphomethylpyrimidine kinase
E6A57_RS09440	COG4115	mRNA cleavage
E6A57_RS09455	COG1121	(ABC) transporter
E6A57_RS09470	COG3442	glutamine amidotransferase
E6A57_RS09475	COG0791	NLP P60 protein
E6A57_RS09505	COG0697	spore germination
E6A57_RS09525	COG0488	(ABC) transporter
E6A57_RS09545	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
E6A57_RS09550	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
E6A57_RS09555	COG0516	GMP reductase activity
E6A57_RS09575	COG2502	aspartate--ammonia ligase
E6A57_RS09585	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
E6A57_RS09595	COG1113	amino acid transport
E6A57_RS09600	COG0681	Belongs to the peptidase S26 family
E6A57_RS09605	COG1132	(ABC) transporter
E6A57_RS09610	COG0542	response to heat
E6A57_RS09640	COG2244	polysaccharide biosynthetic process
E6A57_RS09660	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
E6A57_RS09665	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
E6A57_RS09670	COG1696	Membrane protein involved in D-alanine export
E6A57_RS09675	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
E6A57_RS09695	COG0517	IMP dehydrogenase activity
E6A57_RS09695	COG0516	GMP reductase activity
E6A57_RS09700	COG2217	Heavy metal translocating P-type atpase
E6A57_RS09740	COG1396	sequence-specific DNA binding
E6A57_RS09755	COG0577	efflux transmembrane transporter activity
E6A57_RS09755	COG1136	(ABC) transporter
E6A57_RS09760	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
E6A57_RS09770	COG1744	ABC transporter substrate-binding protein PnrA-like
E6A57_RS09775	COG1744	ABC transporter substrate-binding protein PnrA-like
E6A57_RS09795	COG0656	L-ascorbic acid biosynthetic process
E6A57_RS09800	COG0363	glucosamine-6-phosphate deaminase activity
E6A57_RS09805	COG1428	Deoxynucleoside kinase
E6A57_RS09810	COG1428	Deoxynucleoside kinase
E6A57_RS09820	COG0561	phosphatase activity
E6A57_RS09825	COG2252	PERMEase
E6A57_RS09845	COG0789	Transcriptional regulator
E6A57_RS09850	COG2252	PERMEase
E6A57_RS09880	COG1373	ATPase (AAA superfamily
E6A57_RS09890	COG2252	PERMEase
E6A57_RS09935	COG0813	purine-nucleoside phosphorylase activity
E6A57_RS09975	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
E6A57_RS10000	COG3716	PTS system mannose fructose sorbose family IID component
E6A57_RS10010	COG0477	Major facilitator Superfamily
E6A57_RS10045	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
E6A57_RS10055	COG0028	Belongs to the TPP enzyme family
E6A57_RS10060	COG0445	tRNA wobble uridine modification
E6A57_RS10065	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
E6A57_RS10070	COG0706	membrane insertase activity
E6A57_RS10075	COG0594	ribonuclease P activity
E6A57_RS10080	COG0230	Belongs to the bacterial ribosomal protein bL34 family