locus-tag	class	description
LCU_RS00170	COG0583	DNA-binding transcription factor activity
LCU_RS00175	COG0281	malic enzyme
LCU_RS00185	COG0251	oxidation-reduction process
LCU_RS00200	COG0167	dihydroorotate dehydrogenase activity
LCU_RS00205	COG1011	Hydrolase
LCU_RS00220	COG3715	PTS system
LCU_RS00225	COG3716	PTS system mannose fructose sorbose family IID component
LCU_RS00240	COG1028	Short-chain dehydrogenase reductase Sdr
LCU_RS00255	COG0730	response to heat
LCU_RS00270	COG0438	transferase activity, transferring glycosyl groups
LCU_RS00280	COG2084	Dehydrogenase
LCU_RS00290	COG1368	sulfuric ester hydrolase activity
LCU_RS00295	COG0735	belongs to the Fur family
LCU_RS00345	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
LCU_RS00350	COG0477	Major facilitator Superfamily
LCU_RS00355	COG2706	6-phosphogluconolactonase activity
LCU_RS00365	COG0628	permease
LCU_RS00370	COG2153	protein acetylation
LCU_RS00375	COG0516	GMP reductase activity
LCU_RS00385	COG2226	methyltransferase
LCU_RS00400	COG1674	ftsk spoiiie
LCU_RS00405	COG0612	Peptidase, M16
LCU_RS00410	COG0612	Peptidase, M16
LCU_RS00415	COG1028	Short-chain dehydrogenase reductase Sdr
LCU_RS00420	COG1426	Protein conserved in bacteria
LCU_RS00425	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
LCU_RS00430	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
LCU_RS00435	COG1418	mRNA catabolic process
LCU_RS00445	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
LCU_RS00450	COG1739	Uncharacterized protein family UPF0029
LCU_RS00455	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
LCU_RS00460	COG1040	competence protein
LCU_RS00470	COG0653	protein targeting
LCU_RS00480	COG2884	Cell division ATP-binding protein ftsE
LCU_RS00485	COG2177	Part of the ABC transporter FtsEX involved in
LCU_RS00495	COG0745	RESPONSE REGULATOR receiver
LCU_RS00500	COG5002	protein histidine kinase activity
LCU_RS00510	COG0573	inorganic phosphate transmembrane transporter activity
LCU_RS00515	COG0581	inorganic phosphate transmembrane transporter activity
LCU_RS00520	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
LCU_RS00525	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
LCU_RS00530	COG0704	Plays a role in the regulation of phosphate uptake
LCU_RS00545	COG1983	PspC domain protein
LCU_RS00555	COG1950	PFAM Membrane protein of
LCU_RS00560	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
LCU_RS00565	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
LCU_RS00570	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
LCU_RS00580	COG0492	ferredoxin-NADP+ reductase activity
LCU_RS00585	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
LCU_RS00595	COG0556	nucleotide-excision repair
LCU_RS00600	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
LCU_RS00610	COG1660	Displays ATPase and GTPase activities
LCU_RS00615	COG0391	Required for morphogenesis under gluconeogenic growth conditions
LCU_RS00620	COG1481	regulation of sporulation
LCU_RS00635	COG0740	serine-type endopeptidase activity
LCU_RS00645	COG1472	Belongs to the glycosyl hydrolase 3 family
LCU_RS00655	COG1957	nucleoside hydrolase
LCU_RS00700	COG2094	Belongs to the DNA glycosylase MPG family
LCU_RS00705	COG1131	(ABC) transporter
LCU_RS00715	COG4585	Histidine kinase
LCU_RS00720	COG4585	Histidine kinase
LCU_RS00735	COG4166	transmembrane transport
LCU_RS00740	COG1764	response to oxidative stress
LCU_RS00810	COG0446	pyridine nucleotide-disulphide oxidoreductase
LCU_RS00820	COG0584	glycerophosphoryl diester phosphodiesterase
LCU_RS00840	COG2826	transposase and inactivated derivatives, IS30 family
LCU_RS00850	COG2390	Transcriptional regulator
LCU_RS00860	COG0126	phosphoglycerate kinase activity
LCU_RS00865	COG0149	triose-phosphate isomerase activity
LCU_RS00870	COG0148	phosphopyruvate hydratase activity
LCU_RS00875	COG3711	transcriptional antiterminator
LCU_RS00875	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
LCU_RS00885	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LCU_RS00885	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LCU_RS00885	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
LCU_RS00890	COG1438	arginine binding
LCU_RS00895	COG0564	pseudouridine synthase activity
LCU_RS00900	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
LCU_RS00905	COG3679	Belongs to the UPF0342 family
LCU_RS00910	COG0420	3'-5' exonuclease activity
LCU_RS00915	COG4717	serine-type aminopeptidase activity
LCU_RS00920	COG3481	metal-dependent phosphohydrolase, HD sub domain
LCU_RS00925	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
LCU_RS00935	COG0537	adenosine 5'-monophosphoramidase activity
LCU_RS00940	COG1131	(ABC) transporter
LCU_RS00945	COG4473	ABC transporter
LCU_RS00950	COG0510	thiamine kinase activity
LCU_RS00955	COG0220	tRNA (guanine-N7-)-methyltransferase activity
LCU_RS00965	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LCU_RS00970	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LCU_RS00975	COG0367	asparagine synthase
LCU_RS00980	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
LCU_RS00985	COG0670	Belongs to the BI1 family
LCU_RS01000	COG1607	acyl-coa hydrolase
LCU_RS01005	COG2936	dipeptidyl-peptidase activity
LCU_RS01015	COG1694	Mazg nucleotide pyrophosphohydrolase
LCU_RS01020	COG1278	Cold shock
LCU_RS01035	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
LCU_RS01050	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
LCU_RS01055	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
LCU_RS01060	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
LCU_RS01070	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
LCU_RS01075	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
LCU_RS01080	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
LCU_RS01085	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
LCU_RS01090	COG0047	phosphoribosylformylglycinamidine synthase activity
LCU_RS01095	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
LCU_RS01100	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
LCU_RS01105	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
LCU_RS01110	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
LCU_RS01115	COG0138	bifunctional purine biosynthesis protein purh
LCU_RS01120	COG0151	Belongs to the GarS family
LCU_RS01140	COG0261	This protein binds to 23S rRNA in the presence of protein L20
LCU_RS01150	COG0211	Belongs to the bacterial ribosomal protein bL27 family
LCU_RS01155	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
LCU_RS01160	COG1302	Protein conserved in bacteria
LCU_RS01165	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
LCU_RS01170	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
LCU_RS01175	COG1570	exodeoxyribonuclease VII activity
LCU_RS01180	COG1722	exodeoxyribonuclease VII activity
LCU_RS01190	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
LCU_RS01195	COG1438	arginine binding
LCU_RS01200	COG0497	DNA recombination
LCU_RS01215	COG0194	GDP metabolic process
LCU_RS01220	COG1758	RNA polymerase activity
LCU_RS01225	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
LCU_RS01230	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
LCU_RS01235	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
LCU_RS01240	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
LCU_RS01240	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
LCU_RS01250	COG2815	serine threonine protein kinase
LCU_RS01250	COG0515	serine threonine protein kinase
LCU_RS01255	COG1162	GTPase activity
LCU_RS01260	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
LCU_RS01265	COG1564	THIamine pyrophosphokinase
LCU_RS01270	COG0227	Belongs to the bacterial ribosomal protein bL28 family
LCU_RS01275	COG1302	Protein conserved in bacteria
LCU_RS01280	COG1461	Dihydroxyacetone kinase
LCU_RS01285	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
LCU_RS01290	COG0416	fatty acid biosynthetic process
LCU_RS01295	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LCU_RS01300	COG4166	transmembrane transport
LCU_RS01305	COG0601	transmembrane transport
LCU_RS01310	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LCU_RS01315	COG0444	Belongs to the ABC transporter superfamily
LCU_RS01320	COG4608	Belongs to the ABC transporter superfamily
LCU_RS01325	COG0571	ribonuclease III activity
LCU_RS01330	COG1196	nuclear chromosome segregation
LCU_RS01335	COG0552	protein localization to endoplasmic reticulum
LCU_RS01340	COG1929	Belongs to the glycerate kinase type-1 family
LCU_RS01350	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
LCU_RS01355	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
LCU_RS01360	COG0228	four-way junction DNA binding
LCU_RS01365	COG1837	Belongs to the UPF0109 family
LCU_RS01370	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
LCU_RS01375	COG0336	Belongs to the RNA methyltransferase TrmD family
LCU_RS01380	COG0335	large ribosomal subunit rRNA binding
LCU_RS01415	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
LCU_RS01430	COG2264	protein methyltransferase activity
LCU_RS01435	COG1385	rRNA (uridine-N3-)-methyltransferase activity
LCU_RS01445	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
LCU_RS01450	COG1490	D-aminoacyl-tRNA deacylase activity
LCU_RS01470	COG2001	Belongs to the MraZ family
LCU_RS01475	COG0275	rRNA processing
LCU_RS01485	COG0768	penicillin binding
LCU_RS01490	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
LCU_RS01495	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
LCU_RS01500	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
LCU_RS01520	COG1799	cell septum assembly
LCU_RS01530	COG2302	S4 RNA-binding domain
LCU_RS01535	COG3599	regulation of cell shape
LCU_RS01540	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
LCU_RS01575	COG1609	Transcriptional regulator
LCU_RS01585	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
LCU_RS01590	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
LCU_RS01605	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
LCU_RS01615	COG2814	Major facilitator Superfamily
LCU_RS01620	COG3853	Toxic anion resistance protein (TelA)
LCU_RS01630	COG0494	nUDIX hydrolase
LCU_RS01640	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
LCU_RS01660	COG1122	ATPase activity
LCU_RS01665	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
LCU_RS01670	COG0310	cobalt ion transport
LCU_RS01675	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
LCU_RS01680	COG3875	lactate racemase activity
LCU_RS01685	COG1691	(AIR) carboxylase
LCU_RS01690	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
LCU_RS01695	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
LCU_RS01700	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
LCU_RS01710	COG1606	tRNA processing
LCU_RS01715	COG1104	cysteine desulfurase activity
LCU_RS01725	COG0482	sulfurtransferase activity
LCU_RS01730	COG0446	pyridine nucleotide-disulphide oxidoreductase
LCU_RS01745	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
LCU_RS01755	COG1597	lipid kinase activity
LCU_RS01765	COG5503	Protein of unknown function (DUF1447)
LCU_RS01785	COG0242	peptide deformylase activity
LCU_RS01820	COG0483	inositol monophosphate 1-phosphatase activity
LCU_RS01825	COG1217	gtp-binding protein TYPA
LCU_RS01830	COG4838	Belongs to the UPF0358 family
LCU_RS01835	COG0772	Belongs to the SEDS family
LCU_RS01845	COG4471	UPF0298 protein
LCU_RS01850	COG0742	ribosomal rna small subunit methyltransferase
LCU_RS01855	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
LCU_RS01860	COG3480	Lon protease (S16) C-terminal proteolytic domain
LCU_RS01865	COG1555	photosystem II stabilization
LCU_RS01865	COG1596	polysaccharide export
LCU_RS01870	COG2131	deaminase
LCU_RS01875	COG0658	competence protein
LCU_RS01875	COG2333	competence protein COMEC
LCU_RS01880	COG1466	dna polymerase III delta subunit
LCU_RS01885	COG0268	Binds directly to 16S ribosomal RNA
LCU_RS01890	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
LCU_RS01905	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
LCU_RS01910	COG0544	peptidyl-prolyl cis-trans isomerase activity
LCU_RS01915	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
LCU_RS01920	COG0218	Necessary for normal cell division and for the maintenance of normal septation
LCU_RS01930	COG0765	amino acid transport
LCU_RS01935	COG1126	abc transporter atp-binding protein
LCU_RS01940	COG0322	excinuclease ABC activity
LCU_RS01975	COG1846	Transcriptional regulator
LCU_RS01985	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
LCU_RS01990	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
LCU_RS01990	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LCU_RS01990	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LCU_RS01995	COG1105	Belongs to the carbohydrate kinase PfkB family
LCU_RS02000	COG1349	DNA-binding transcription factor activity
LCU_RS02010	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
LCU_RS02020	COG1234	tRNA 3'-trailer cleavage
LCU_RS02025	COG0300	oxidoreductase activity
LCU_RS02030	COG5416	Lipopolysaccharide assembly protein A domain
LCU_RS02040	COG0542	response to heat
LCU_RS02045	COG0333	Belongs to the bacterial ribosomal protein bL32 family
LCU_RS02055	COG0531	amino acid
LCU_RS02070	COG0587	DNA-directed DNA polymerase activity
LCU_RS02085	COG2707	UPF0756 membrane protein
LCU_RS02090	COG2996	Protein conserved in bacteria
LCU_RS02095	COG0735	belongs to the Fur family
LCU_RS02110	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
LCU_RS02115	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
LCU_RS02120	COG1187	pseudouridine synthase activity
LCU_RS02125	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
LCU_RS02130	COG1141	Ferredoxin
LCU_RS02140	COG0514	ATP-dependent DNA helicase (RecQ)
LCU_RS02150	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
LCU_RS02155	COG0539	negative regulation of cytoplasmic translation
LCU_RS02160	COG1160	GTP binding
LCU_RS02170	COG0457	Tetratricopeptide repeat
LCU_RS02175	COG1136	(ABC) transporter
LCU_RS02175	COG0577	efflux transmembrane transporter activity
LCU_RS02195	COG2814	Major facilitator Superfamily
LCU_RS02200	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
LCU_RS02205	COG0617	tRNA 3'-terminal CCA addition
LCU_RS02215	COG0488	(ABC) transporter
LCU_RS02220	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
LCU_RS02230	COG1307	EDD domain protein, DegV family
LCU_RS02235	COG2755	lipolytic protein G-D-S-L family
LCU_RS02245	COG4479	Belongs to the UPF0346 family
LCU_RS02260	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
LCU_RS02330	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
LCU_RS02340	COG0629	single-stranded DNA binding
LCU_RS02520	COG0758	DNA mediated transformation
LCU_RS02525	COG0702	epimerase
LCU_RS02530	COG1959	2 iron, 2 sulfur cluster binding
LCU_RS02535	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
LCU_RS02540	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
LCU_RS02555	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
LCU_RS02565	COG0028	Belongs to the TPP enzyme family
LCU_RS02570	COG3527	Alpha-acetolactate decarboxylase
LCU_RS02575	COG0351	phosphomethylpyrimidine kinase
LCU_RS02580	COG4619	ABC transporter
LCU_RS02585	COG0390	transport system, permease component
LCU_RS02590	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
LCU_RS02600	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
LCU_RS02610	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
LCU_RS02620	COG1227	inorganic diphosphatase activity
LCU_RS02640	COG4974	Belongs to the 'phage' integrase family
LCU_RS02675	COG1309	transcriptional regulator
LCU_RS02680	COG1307	EDD domain protein, DegV family
LCU_RS02685	COG1272	protein, Hemolysin III
LCU_RS02695	COG1307	EDD domain protein, DegV family
LCU_RS02705	COG1293	RNA-binding protein homologous to eukaryotic snRNP
LCU_RS02715	COG0284	orotidine-5'-phosphate decarboxylase activity
LCU_RS02720	COG0167	dihydroorotate dehydrogenase activity
LCU_RS02725	COG0543	2 iron, 2 sulfur cluster binding
LCU_RS02730	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
LCU_RS02735	COG0505	Belongs to the CarA family
LCU_RS02740	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
LCU_RS02745	COG0540	Belongs to the ATCase OTCase family
LCU_RS02750	COG2233	PERMEase
LCU_RS02755	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
LCU_RS02760	COG0564	pseudouridine synthase activity
LCU_RS02765	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
LCU_RS02770	COG2759	Belongs to the formate--tetrahydrofolate ligase family
LCU_RS02775	COG1278	Cold shock
LCU_RS02785	COG0328	RNA-DNA hybrid ribonuclease activity
LCU_RS02790	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LCU_RS02795	COG1393	Belongs to the ArsC family
LCU_RS02805	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LCU_RS02845	COG3655	Transcriptional regulator
LCU_RS02850	COG0095	Lipoate-protein ligase
LCU_RS02860	COG1131	(ABC) transporter
LCU_RS02865	COG2186	Transcriptional regulator
LCU_RS02885	COG0582	viral genome integration into host DNA
LCU_RS02910	COG0116	Belongs to the methyltransferase superfamily
LCU_RS02920	COG3599	regulation of cell shape
LCU_RS02925	COG4474	Belongs to the UPF0398 family
LCU_RS02930	COG3331	DNA recombination
LCU_RS02935	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
LCU_RS02940	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
LCU_RS02950	COG0017	Asparaginyl-tRNA synthetase
LCU_RS02960	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
LCU_RS02960	COG1199	ATP-dependent helicase activity
LCU_RS02965	COG1074	ATP-dependent DNA helicase activity
LCU_RS02970	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
LCU_RS02975	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
LCU_RS02990	COG1304	FMN binding
LCU_RS02995	COG0604	alcohol dehydrogenase
LCU_RS03000	COG1733	regulation of RNA biosynthetic process
LCU_RS03005	COG1476	TRANSCRIPTIONal
LCU_RS03025	COG2151	metal-sulfur cluster biosynthetic enzyme
LCU_RS03030	COG0561	phosphatase activity
LCU_RS03035	COG1942	4-Oxalocrotonate Tautomerase
LCU_RS03070	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
LCU_RS03075	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
LCU_RS03080	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
LCU_RS03105	COG0710	3-dehydroquinate dehydratase activity
LCU_RS03110	COG2195	Cleaves the N-terminal amino acid of tripeptides
LCU_RS03115	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
LCU_RS03120	COG2384	SAM-dependent methyltransferase
LCU_RS03135	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
LCU_RS03140	COG0358	DNA primase activity
LCU_RS03145	COG3189	MarR family transcriptional regulator
LCU_RS03150	COG0751	glycine-tRNA ligase activity
LCU_RS03155	COG0752	glycyl-tRNA synthetase alpha subunit
LCU_RS03160	COG1381	Involved in DNA repair and RecF pathway recombination
LCU_RS03175	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
LCU_RS03180	COG1702	phosphate starvation-inducible protein PhoH
LCU_RS03185	COG1610	YqeY-like protein
LCU_RS03190	COG0828	Belongs to the bacterial ribosomal protein bS21 family
LCU_RS03195	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
LCU_RS03210	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
LCU_RS03215	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
LCU_RS03220	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
LCU_RS03230	COG0124	histidyl-tRNA synthetase
LCU_RS03235	COG0860	N-Acetylmuramoyl-L-alanine amidase
LCU_RS03235	COG3103	Sh3 type 3 domain protein
LCU_RS03235	COG4991	sh3 domain protein
LCU_RS03245	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LCU_RS03255	COG1126	abc transporter atp-binding protein
LCU_RS03260	COG0765	amino acid transport
LCU_RS03265	COG2894	cell division
LCU_RS03280	COG1792	Involved in formation and maintenance of cell shape
LCU_RS03285	COG1077	Cell shape determining protein MreB Mrl
LCU_RS03290	COG2003	Belongs to the UPF0758 family
LCU_RS03295	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
LCU_RS03305	COG0525	valine-tRNA ligase activity
LCU_RS03310	COG0301	tRNA thio-modification
LCU_RS03315	COG1104	cysteine desulfurase activity
LCU_RS03320	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
LCU_RS03325	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
LCU_RS03330	COG4493	Belongs to the UPF0637 family
LCU_RS03345	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
LCU_RS03365	COG2826	transposase and inactivated derivatives, IS30 family
LCU_RS03370	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
LCU_RS03380	COG5294	Protein conserved in bacteria
LCU_RS03405	COG1956	GAF domain-containing protein
LCU_RS03410	COG2096	Adenosyltransferase
LCU_RS03435	COG2801	Transposase and inactivated derivatives
LCU_RS03440	COG2826	transposase and inactivated derivatives, IS30 family
LCU_RS03450	COG0719	Fe-S assembly protein
LCU_RS03460	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
LCU_RS03465	COG0719	Fe-S assembly protein
LCU_RS03500	COG1518	maintenance of DNA repeat elements
LCU_RS03510	COG1464	Belongs to the NlpA lipoprotein family
LCU_RS03515	COG2011	ABC-type metal ion transport system permease component
LCU_RS03520	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
LCU_RS03525	COG0509	glycine decarboxylation via glycine cleavage system
LCU_RS03530	COG0772	Belongs to the SEDS family
LCU_RS03540	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
LCU_RS03555	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
LCU_RS03565	COG0355	proton-transporting ATP synthase activity, rotational mechanism
LCU_RS03570	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
LCU_RS03575	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
LCU_RS03580	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
LCU_RS03585	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
LCU_RS03590	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
LCU_RS03595	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
LCU_RS03600	COG0356	it plays a direct role in the translocation of protons across the membrane
LCU_RS03605	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
LCU_RS03610	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
LCU_RS03615	COG0009	L-threonylcarbamoyladenylate synthase
LCU_RS03620	COG2890	protein-(glutamine-N5) methyltransferase activity
LCU_RS03625	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
LCU_RS03630	COG1435	thymidine kinase activity
LCU_RS03635	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
LCU_RS03640	COG3442	glutamine amidotransferase
LCU_RS03650	COG1418	mRNA catabolic process
LCU_RS03655	COG1482	cell wall glycoprotein biosynthetic process
LCU_RS03660	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
LCU_RS03665	COG1132	(ABC) transporter
LCU_RS03685	COG1136	(ABC) transporter
LCU_RS03685	COG0577	efflux transmembrane transporter activity
LCU_RS03690	COG0577	efflux transmembrane transporter activity
LCU_RS03715	COG1803	Methylglyoxal synthase
LCU_RS03820	COG5492	domain, Protein
LCU_RS03890	COG0270	DNA (cytosine-5-)-methyltransferase activity
LCU_RS03945	COG0556	nucleotide-excision repair
LCU_RS03975	COG1396	sequence-specific DNA binding
LCU_RS03990	COG4974	Belongs to the 'phage' integrase family
LCU_RS04015	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
LCU_RS04030	COG3158	transport of potassium into the cell
LCU_RS04040	COG2723	6-phospho-beta-galactosidase activity
LCU_RS04045	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
LCU_RS04060	COG0589	response to stress
LCU_RS04070	COG4990	cell redox homeostasis
LCU_RS04095	COG0166	Belongs to the GPI family
LCU_RS04105	COG4120	Belongs to the binding-protein-dependent transport system permease family
LCU_RS04110	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
LCU_RS04115	COG0028	Belongs to the TPP enzyme family
LCU_RS04125	COG4221	oxidoreductase activity
LCU_RS04130	COG1733	regulation of RNA biosynthetic process
LCU_RS04170	COG3394	polysaccharide catabolic process
LCU_RS04175	COG2190	(PTS) system
LCU_RS04175	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LCU_RS04175	COG1263	PTS System
LCU_RS04180	COG0366	Alpha amylase catalytic
LCU_RS04190	COG2188	Transcriptional regulator
LCU_RS04200	COG2814	Major facilitator Superfamily
LCU_RS04205	COG4485	Bacterial membrane protein, YfhO
LCU_RS04210	COG4975	Glucose uptake
LCU_RS04225	COG1368	sulfuric ester hydrolase activity
LCU_RS04245	COG0402	S-adenosylhomocysteine deaminase activity
LCU_RS04250	COG5002	protein histidine kinase activity
LCU_RS04250	COG3850	Histidine kinase
LCU_RS04255	COG0745	RESPONSE REGULATOR receiver
LCU_RS04260	COG0561	phosphatase activity
LCU_RS04265	COG0531	amino acid
LCU_RS04280	COG0443	Heat shock 70 kDa protein
LCU_RS04285	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
LCU_RS04295	COG0635	Involved in the biosynthesis of porphyrin-containing compound
LCU_RS04300	COG0196	riboflavin kinase activity
LCU_RS04305	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
LCU_RS04320	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
LCU_RS04325	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
LCU_RS04335	COG2740	Nucleic-acid-binding protein implicated in transcription termination
LCU_RS04340	COG0195	Participates in both transcription termination and antitermination
LCU_RS04350	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LCU_RS04385	COG4974	Belongs to the 'phage' integrase family
LCU_RS04420	COG2176	DNA-directed DNA polymerase activity
LCU_RS04425	COG0442	prolyl-tRNA aminoacylation
LCU_RS04430	COG0750	zinc metalloprotease
LCU_RS04435	COG4589	Belongs to the CDS family
LCU_RS04440	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
LCU_RS04450	COG0233	cytoplasmic translational termination
LCU_RS04455	COG0528	UMP kinase activity
LCU_RS04460	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
LCU_RS04465	COG0052	Belongs to the universal ribosomal protein uS2 family
LCU_RS04470	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LCU_RS04475	COG2827	Endonuclease containing a URI domain
LCU_RS04480	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
LCU_RS04485	COG0204	Acyl-transferase
LCU_RS04495	COG1073	alpha beta
LCU_RS04500	COG1132	(ABC) transporter
LCU_RS04505	COG1132	(ABC) transporter
LCU_RS04510	COG3763	UPF0154 protein
LCU_RS04515	COG4224	UPF0291 protein
LCU_RS04520	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
LCU_RS04525	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
LCU_RS04530	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
LCU_RS04530	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
LCU_RS04535	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
LCU_RS04540	COG3759	membrane
LCU_RS04545	COG0393	Putative heavy-metal-binding
LCU_RS04595	COG5484	DNA packaging
LCU_RS04620	COG4974	Belongs to the 'phage' integrase family
LCU_RS04625	COG0481	GTPase activity
LCU_RS04650	COG3152	Membrane
LCU_RS04665	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
LCU_RS04670	COG0827	DNA restriction-modification system
LCU_RS04695	COG1459	type II secretion system
LCU_RS04700	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
LCU_RS04705	COG0217	transcriptional regulatory protein
LCU_RS04735	COG2855	membrane
LCU_RS04740	COG0583	DNA-binding transcription factor activity
LCU_RS04745	COG0534	Mate efflux family protein
LCU_RS04755	COG0564	pseudouridine synthase activity
LCU_RS04760	COG0431	NADPH-dependent FMN reductase
LCU_RS04765	COG2249	NAD(P)H dehydrogenase (quinone) activity
LCU_RS04770	COG0174	glutamine synthetase
LCU_RS04775	COG0789	Transcriptional regulator
LCU_RS04780	COG0519	Catalyzes the synthesis of GMP from XMP
LCU_RS04790	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
LCU_RS04795	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
LCU_RS04810	COG1940	carbohydrate kinase activity
LCU_RS04825	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
LCU_RS04830	COG0267	Belongs to the bacterial ribosomal protein bL33 family
LCU_RS04835	COG0768	penicillin binding
LCU_RS04840	COG4485	Bacterial membrane protein, YfhO
LCU_RS04845	COG0025	NhaP-type Na H and K H
LCU_RS04850	COG0812	UDP-N-acetylmuramate dehydrogenase activity
LCU_RS04855	COG0708	Exodeoxyribonuclease III
LCU_RS04860	COG2176	DNA-directed DNA polymerase activity
LCU_RS04865	COG0697	spore germination
LCU_RS04875	COG0802	atpase or kinase
LCU_RS04880	COG0280	phosphate acetyltransferase
LCU_RS04885	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
LCU_RS04890	COG0561	phosphatase activity
LCU_RS04915	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LCU_RS04920	COG0352	thiamine-phosphate diphosphorylase activity
LCU_RS04920	COG0351	phosphomethylpyrimidine kinase
LCU_RS04925	COG4720	Psort location CytoplasmicMembrane, score
LCU_RS04930	COG4475	Protein of unknown function (DUF436)
LCU_RS04935	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
LCU_RS04945	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
LCU_RS04965	COG1177	transmembrane transport
LCU_RS04970	COG1176	ABC-type spermidine putrescine transport system, permease component I
LCU_RS04975	COG3842	ATPase activity
LCU_RS04980	COG0604	alcohol dehydrogenase
LCU_RS04985	COG4841	protein insertion into membrane
LCU_RS04995	COG4585	Histidine kinase
LCU_RS05005	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
LCU_RS05010	COG0572	uridine kinase
LCU_RS05015	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
LCU_RS05020	COG0072	phenylalanine-tRNA ligase activity
LCU_RS05025	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
LCU_RS05030	COG1733	regulation of RNA biosynthetic process
LCU_RS05040	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LCU_RS05045	COG1254	Belongs to the acylphosphatase family
LCU_RS05050	COG0706	membrane insertase activity
LCU_RS05055	COG5002	protein histidine kinase activity
LCU_RS05060	COG0745	RESPONSE REGULATOR receiver
LCU_RS05065	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
LCU_RS05075	COG1323	Belongs to the UPF0348 family
LCU_RS05080	COG2226	methyltransferase
LCU_RS05085	COG0799	negative regulation of ribosome biogenesis
LCU_RS05090	COG1713	HD superfamily hydrolase involved in NAD metabolism
LCU_RS05095	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
LCU_RS05105	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
LCU_RS05110	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
LCU_RS05115	COG1063	alcohol dehydrogenase
LCU_RS05120	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
LCU_RS05125	COG0291	Belongs to the bacterial ribosomal protein bL35 family
LCU_RS05130	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
LCU_RS05135	COG1304	FMN binding
LCU_RS05140	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
LCU_RS05145	COG1484	DNA-dependent DNA replication
LCU_RS05150	COG3611	Membrane attachment protein
LCU_RS05155	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
LCU_RS05160	COG0237	dephospho-CoA kinase activity
LCU_RS05165	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
LCU_RS05180	COG3584	3D domain protein
LCU_RS05180	COG3583	domain protein
LCU_RS05185	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
LCU_RS05190	COG0557	exoribonuclease II activity
LCU_RS05200	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
LCU_RS05215	COG1073	alpha beta
LCU_RS05220	COG0018	arginyl-trna synthetase
LCU_RS05225	COG1136	(ABC) transporter
LCU_RS05225	COG0577	efflux transmembrane transporter activity
LCU_RS05240	COG0531	amino acid
LCU_RS05250	COG0561	phosphatase activity
LCU_RS05270	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
LCU_RS05275	COG1187	pseudouridine synthase activity
LCU_RS05280	COG2244	polysaccharide biosynthetic process
LCU_RS05290	COG1733	regulation of RNA biosynthetic process
LCU_RS05295	COG1113	amino acid transport
LCU_RS05300	COG0495	leucyl-tRNA aminoacylation
LCU_RS05305	COG1388	LysM domain
LCU_RS05305	COG1705	Flagellar rod assembly protein muramidase FlgJ
LCU_RS05310	COG0671	phosphoesterase, PA-phosphatase related
LCU_RS05315	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
LCU_RS05320	COG3142	Participates in the control of copper homeostasis
LCU_RS05325	COG1968	undecaprenyl-diphosphatase activity
LCU_RS05330	COG0564	pseudouridine synthase activity
LCU_RS05335	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
LCU_RS05340	COG2357	RelA SpoT domain protein
LCU_RS05360	COG4862	establishment of competence for transformation
LCU_RS05365	COG1393	Belongs to the ArsC family
LCU_RS05370	COG1234	tRNA 3'-trailer cleavage
LCU_RS05380	COG0577	efflux transmembrane transporter activity
LCU_RS05385	COG1136	(ABC) transporter
LCU_RS05390	COG0745	RESPONSE REGULATOR receiver
LCU_RS05395	COG0642	Histidine kinase
LCU_RS05410	COG0602	queuosine metabolic process
LCU_RS05420	COG2217	Heavy metal translocating P-type atpase
LCU_RS05445	COG0542	response to heat
LCU_RS05465	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
LCU_RS05470	COG1253	flavin adenine dinucleotide binding
LCU_RS05475	COG0628	permease
LCU_RS05490	COG3557	Belongs to the UPF0374 family
LCU_RS05495	COG1194	a g-specific adenine glycosylase
LCU_RS05500	COG2137	regulation of response to DNA damage stimulus
LCU_RS05510	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
LCU_RS05530	COG3425	synthase
LCU_RS05540	COG0183	Belongs to the thiolase family
LCU_RS05575	COG0765	amino acid transport
LCU_RS05580	COG0242	peptide deformylase activity
LCU_RS05585	COG1210	Utp--glucose-1-phosphate uridylyltransferase
LCU_RS05600	COG1091	dTDP-4-dehydrorhamnose reductase activity
LCU_RS05605	COG1088	dTDP-glucose 4,6-dehydratase activity
LCU_RS05615	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
LCU_RS05625	COG1215	transferase activity, transferring glycosyl groups
LCU_RS05645	COG0297	glycogen (starch) synthase activity
LCU_RS05655	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
LCU_RS05660	COG0489	protein tyrosine kinase activity
LCU_RS05670	COG1316	TRANSCRIPTIONal
LCU_RS05680	COG0024	Methionine aminopeptidase
LCU_RS05685	COG0716	FMN binding
LCU_RS05695	COG2246	polysaccharide biosynthetic process
LCU_RS05700	COG0463	Glycosyl transferase, family 2
LCU_RS05705	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
LCU_RS05715	COG2309	aminopeptidase activity
LCU_RS05730	COG2076	Multidrug Resistance protein
LCU_RS05750	COG0477	Major facilitator Superfamily
LCU_RS05755	COG1827	regulation of RNA biosynthetic process
LCU_RS05760	COG2723	6-phospho-beta-galactosidase activity
LCU_RS05770	COG1447	Phosphotransferase system cellobiose-specific component IIA
LCU_RS05780	COG0673	inositol 2-dehydrogenase activity
LCU_RS05815	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
LCU_RS05820	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
LCU_RS05825	COG1597	lipid kinase activity
LCU_RS05830	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
LCU_RS05835	COG0154	amidase activity
LCU_RS05850	COG1959	2 iron, 2 sulfur cluster binding
LCU_RS05865	COG4851	CamS sex pheromone cAM373 precursor
LCU_RS05870	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
LCU_RS05880	COG0561	phosphatase activity
LCU_RS05885	COG1609	Transcriptional regulator
LCU_RS05890	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
LCU_RS05895	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
LCU_RS05900	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
LCU_RS05905	COG1705	Flagellar rod assembly protein muramidase FlgJ
LCU_RS05910	COG0673	inositol 2-dehydrogenase activity
LCU_RS05920	COG1278	Cold shock
LCU_RS05945	COG3091	SprT-like family
LCU_RS05950	COG2183	response to ionizing radiation
LCU_RS05965	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
LCU_RS05970	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
LCU_RS05980	COG0463	Glycosyl transferase, family 2
LCU_RS05980	COG1216	Glycosyl transferase, family 2
LCU_RS05990	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
LCU_RS06000	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
LCU_RS06050	COG2188	Transcriptional regulator
LCU_RS06065	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
LCU_RS06080	COG3104	oligopeptide transport
LCU_RS06120	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
LCU_RS06125	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
LCU_RS06130	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
LCU_RS06140	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
LCU_RS06145	COG0037	tRNA processing
LCU_RS06150	COG1098	S1 RNA binding domain
LCU_RS06160	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
LCU_RS06165	COG2244	polysaccharide biosynthetic process
LCU_RS06170	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
LCU_RS06175	COG0193	aminoacyl-tRNA hydrolase activity
LCU_RS06180	COG0039	L-malate dehydrogenase activity
LCU_RS06195	COG4708	membrane
LCU_RS06200	COG2337	Toxic component of a toxin-antitoxin (TA) module
LCU_RS06210	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
LCU_RS06215	COG0736	holo-[acyl-carrier-protein] synthase activity
LCU_RS06225	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
LCU_RS06235	COG0501	Belongs to the peptidase M48B family
LCU_RS06240	COG1704	LemA family
LCU_RS06250	COG2814	Major facilitator Superfamily
LCU_RS06260	COG3548	integral membrane protein
LCU_RS06270	COG0254	rRNA binding
LCU_RS06275	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
LCU_RS06280	COG0504	CTP synthase activity
LCU_RS06285	COG1940	carbohydrate kinase activity
LCU_RS06305	COG1078	dGTPase activity
LCU_RS06310	COG0561	phosphatase activity
LCU_RS06320	COG0861	Integral membrane protein TerC family
LCU_RS06325	COG1970	mechanosensitive ion channel activity
LCU_RS06330	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
LCU_RS06340	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
LCU_RS06360	COG2826	transposase and inactivated derivatives, IS30 family
LCU_RS06365	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
LCU_RS06370	COG1461	Dihydroxyacetone kinase
LCU_RS06375	COG2376	Dihydroxyacetone kinase
LCU_RS06380	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
LCU_RS06385	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
LCU_RS06390	COG1846	Transcriptional regulator
LCU_RS06395	COG1511	domain protein
LCU_RS06400	COG4466	Protein conserved in bacteria
LCU_RS06405	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
LCU_RS06410	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
LCU_RS06415	COG0084	hydrolase, TatD family'
LCU_RS06420	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LCU_RS06420	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LCU_RS06425	COG1801	Protein of unknown function DUF72
LCU_RS06455	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
LCU_RS06465	COG4989	oxidoreductase activity
LCU_RS06475	COG0534	Mate efflux family protein
LCU_RS06485	COG3973	AAA domain
LCU_RS06490	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
LCU_RS06500	COG1214	PFAM Peptidase M22, glycoprotease
LCU_RS06505	COG4720	Psort location CytoplasmicMembrane, score
LCU_RS06525	COG4467	Involved in initiation control of chromosome replication
LCU_RS06530	COG0470	DNA polymerase III
LCU_RS06535	COG3870	Protein conserved in bacteria
LCU_RS06540	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
LCU_RS06550	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
LCU_RS06555	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
LCU_RS06560	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
LCU_RS06570	COG0590	tRNA wobble adenosine to inosine editing
LCU_RS06580	COG2813	Specifically methylates the guanine in position
LCU_RS06585	COG0392	lysyltransferase activity
LCU_RS06585	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
LCU_RS06590	COG0222	ribosome binding
LCU_RS06595	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
LCU_RS06600	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
LCU_RS06605	COG2252	PERMEase
LCU_RS06610	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
LCU_RS06615	COG0081	regulation of translation
LCU_RS06620	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
LCU_RS06630	COG0250	Participates in transcription elongation, termination and antitermination
LCU_RS06640	COG0267	Belongs to the bacterial ribosomal protein bL33 family
LCU_RS06650	COG4939	FMN-binding domain protein
LCU_RS06680	COG0561	phosphatase activity
LCU_RS06700	COG1136	(ABC) transporter
LCU_RS06705	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
LCU_RS06720	COG1297	OPT oligopeptide transporter protein
LCU_RS06730	COG1760	l-serine dehydratase
LCU_RS06735	COG0702	epimerase
LCU_RS06765	COG2826	transposase and inactivated derivatives, IS30 family
LCU_RS06785	COG2814	Major facilitator Superfamily
LCU_RS06790	COG3118	belongs to the thioredoxin family
LCU_RS06810	COG0488	(ABC) transporter
LCU_RS06840	COG3479	Phenolic acid decarboxylase
LCU_RS06850	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
LCU_RS06880	COG0778	Nitroreductase
LCU_RS06900	COG0640	Transcriptional regulator
LCU_RS06905	COG2188	Transcriptional regulator
LCU_RS06910	COG2723	6-phospho-beta-galactosidase activity
LCU_RS06915	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
LCU_RS06920	COG1597	lipid kinase activity
LCU_RS06925	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
LCU_RS06930	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
LCU_RS06935	COG0101	tRNA pseudouridine synthase activity
LCU_RS06950	COG1122	ATPase activity
LCU_RS06955	COG1122	ATPase activity
LCU_RS06960	COG0203	ribosomal protein L17
LCU_RS06965	COG0202	RNA polymerase activity
LCU_RS06970	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
LCU_RS06975	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
LCU_RS06980	COG0257	Belongs to the bacterial ribosomal protein bL36 family
LCU_RS06985	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
LCU_RS06990	COG0563	adenylate kinase activity
LCU_RS07000	COG0200	Binds to the 23S rRNA
LCU_RS07005	COG1841	ribosomal large subunit assembly
LCU_RS07010	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
LCU_RS07015	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
LCU_RS07020	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
LCU_RS07025	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
LCU_RS07035	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
LCU_RS07040	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
LCU_RS07045	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
LCU_RS07050	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
LCU_RS07055	COG0255	Belongs to the universal ribosomal protein uL29 family
LCU_RS07060	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
LCU_RS07065	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
LCU_RS07070	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
LCU_RS07075	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
LCU_RS07080	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
LCU_RS07085	COG0089	rRNA binding
LCU_RS07090	COG0088	Forms part of the polypeptide exit tunnel
LCU_RS07095	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
LCU_RS07100	COG0051	transcription antitermination factor activity, RNA binding
LCU_RS07105	COG1335	isochorismatase
LCU_RS07110	COG1162	GTPase activity
LCU_RS07115	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
LCU_RS07120	COG0049	tRNA binding
LCU_RS07125	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
LCU_RS07135	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
LCU_RS07140	COG0085	RNA polymerase activity
LCU_RS07145	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
LCU_RS07150	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
LCU_RS07155	COG0542	response to heat
LCU_RS07160	COG4463	regulation of RNA biosynthetic process
LCU_RS07240	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
LCU_RS07260	COG2723	6-phospho-beta-galactosidase activity
LCU_RS07265	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
LCU_RS07270	COG2188	Transcriptional regulator
LCU_RS07275	COG1511	domain protein
LCU_RS07280	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
LCU_RS07295	COG1428	Deoxynucleoside kinase
LCU_RS07320	COG0833	amino acid
LCU_RS07330	COG1959	2 iron, 2 sulfur cluster binding
LCU_RS07350	COG1757	Na H antiporter
LCU_RS07355	COG0398	Pfam SNARE associated Golgi protein
LCU_RS07360	COG0028	Belongs to the TPP enzyme family
LCU_RS07365	COG2837	iron assimilation
LCU_RS07370	COG0604	alcohol dehydrogenase
LCU_RS07370	COG3321	synthase
LCU_RS07415	COG0577	efflux transmembrane transporter activity
LCU_RS07420	COG1136	(ABC) transporter
LCU_RS07425	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
LCU_RS07435	COG0514	ATP-dependent DNA helicase (RecQ)
LCU_RS07445	COG1881	PFAM PEBP family protein
LCU_RS07460	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
LCU_RS07470	COG0588	phosphoglycerate mutase activity
LCU_RS07485	COG0110	maltose O-acetyltransferase activity
LCU_RS07495	COG1174	glycine betaine transport
LCU_RS07500	COG0517	IMP dehydrogenase activity
LCU_RS07500	COG1125	glycine betaine transport
LCU_RS07505	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LCU_RS07510	COG2814	Major facilitator Superfamily
LCU_RS07530	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
LCU_RS07535	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LCU_RS07540	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
LCU_RS07560	COG0745	RESPONSE REGULATOR receiver
LCU_RS07590	COG1114	Component of the transport system for branched-chain amino acids
LCU_RS07620	COG3764	Sortase (surface protein transpeptidase)
LCU_RS07625	COG2252	PERMEase
LCU_RS07630	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
LCU_RS07645	COG2190	(PTS) system
LCU_RS07645	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LCU_RS07645	COG1263	PTS System
LCU_RS07650	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
LCU_RS07660	COG0352	thiamine-phosphate diphosphorylase activity
LCU_RS07665	COG0110	maltose O-acetyltransferase activity
LCU_RS07670	COG3590	peptidase
LCU_RS07680	COG1668	transmembrane transport
LCU_RS07685	COG4152	abc transporter atp-binding protein
LCU_RS07710	COG1181	Belongs to the D-alanine--D-alanine ligase family
LCU_RS07725	COG0628	permease
LCU_RS07730	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
LCU_RS07750	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
LCU_RS07760	COG1121	(ABC) transporter
LCU_RS07770	COG0519	Catalyzes the synthesis of GMP from XMP
LCU_RS07785	COG2365	Tyrosine phosphatase family
LCU_RS07790	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
LCU_RS07795	COG2814	Major facilitator Superfamily
LCU_RS07830	COG0656	L-ascorbic acid biosynthetic process
LCU_RS07835	COG1253	flavin adenine dinucleotide binding
LCU_RS07840	COG1307	EDD domain protein, DegV family
LCU_RS07865	COG1780	Probably involved in ribonucleotide reductase function
LCU_RS07875	COG1073	alpha beta
LCU_RS07885	COG0012	GTP binding
LCU_RS07890	COG4481	Protein conserved in bacteria
LCU_RS07895	COG1475	DNA binding
LCU_RS07900	COG1192	Involved in chromosome partitioning
LCU_RS07905	COG1475	DNA binding
LCU_RS07910	COG0357	Ribosomal RNA small subunit methyltransferase G
LCU_RS07915	COG2233	PERMEase
LCU_RS07925	COG0438	transferase activity, transferring glycosyl groups
LCU_RS07930	COG0305	Participates in initiation and elongation during chromosome replication
LCU_RS07935	COG0359	binds to the 23S rRNA
LCU_RS07945	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
LCU_RS07950	COG0629	single-stranded DNA binding
LCU_RS07955	COG0360	Binds together with S18 to 16S ribosomal RNA
LCU_RS07960	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
LCU_RS07965	COG0187	DNA topoisomerase II activity
LCU_RS07970	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
LCU_RS07975	COG2501	S4 domain
LCU_RS07980	COG0592	DNA-directed DNA polymerase activity
LCU_RS07985	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
LCU_RS07990	COG0230	Belongs to the bacterial ribosomal protein bL34 family
LCU_RS07995	COG0594	ribonuclease P activity
LCU_RS08000	COG0706	membrane insertase activity
LCU_RS08020	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
LCU_RS08025	COG0445	tRNA wobble uridine modification
LCU_RS08030	COG0488	(ABC) transporter
LCU_RS08050	COG0697	spore germination
LCU_RS08060	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
LCU_RS08065	COG2814	Major facilitator Superfamily
LCU_RS08070	COG1288	antiporter activity
LCU_RS08075	COG0681	Belongs to the peptidase S26 family
LCU_RS08080	COG0588	phosphoglycerate mutase activity
LCU_RS08100	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
LCU_RS08115	COG0194	GDP metabolic process
LCU_RS08125	COG0735	belongs to the Fur family
LCU_RS08160	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
LCU_RS08165	COG1940	carbohydrate kinase activity
LCU_RS08170	COG0531	amino acid
LCU_RS08180	COG1609	Transcriptional regulator
LCU_RS08205	COG3842	ATPase activity
LCU_RS08215	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
LCU_RS08220	COG0366	Alpha amylase catalytic
LCU_RS08225	COG0531	amino acid
LCU_RS08230	COG1136	(ABC) transporter
LCU_RS08255	COG2267	carboxylic ester hydrolase activity
LCU_RS08260	COG0475	glutathione-regulated potassium exporter activity
LCU_RS08260	COG0569	domain protein
LCU_RS08265	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
LCU_RS08270	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
LCU_RS08275	COG3973	AAA domain
LCU_RS08290	COG5617	Psort location CytoplasmicMembrane, score
LCU_RS08295	COG1072	(Pantothenic acid kinase))
LCU_RS08300	COG0519	Catalyzes the synthesis of GMP from XMP
LCU_RS08315	COG0783	Belongs to the Dps family
LCU_RS08350	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LCU_RS08420	COG1121	(ABC) transporter
LCU_RS08425	COG1108	ABC-type Mn2 Zn2 transport systems permease components
LCU_RS08435	COG1442	glycosyl transferase family 8
LCU_RS08450	COG1028	Short-chain dehydrogenase reductase Sdr
LCU_RS08455	COG2261	transglycosylase associated protein
LCU_RS08470	COG1302	Protein conserved in bacteria
LCU_RS08490	COG4690	dipeptidase activity
LCU_RS08505	COG2190	(PTS) system
LCU_RS08505	COG1263	PTS System
LCU_RS08505	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LCU_RS08515	COG1263	PTS System
LCU_RS08515	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LCU_RS08520	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
LCU_RS08535	COG2211	Major facilitator Superfamily
LCU_RS08535	COG2190	(PTS) system
LCU_RS08550	COG0488	(ABC) transporter
LCU_RS08555	COG0531	amino acid
LCU_RS08590	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
LCU_RS08600	COG4975	Glucose uptake
LCU_RS08605	COG1869	D-ribose catabolic process
LCU_RS08615	COG1609	Transcriptional regulator
LCU_RS08625	COG2814	Major facilitator Superfamily
LCU_RS08630	COG0588	phosphoglycerate mutase activity
LCU_RS08635	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
LCU_RS08660	COG0446	pyridine nucleotide-disulphide oxidoreductase
LCU_RS08675	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
LCU_RS08680	COG3118	belongs to the thioredoxin family
LCU_RS08720	COG1940	carbohydrate kinase activity
LCU_RS08730	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
LCU_RS08740	COG3933	PFAM sigma-54 factor interaction domain-containing protein
LCU_RS08740	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
LCU_RS08745	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
LCU_RS08750	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LCU_RS08755	COG3715	PTS system
LCU_RS08760	COG3716	PTS system mannose fructose sorbose family IID component
LCU_RS08780	COG0583	DNA-binding transcription factor activity
LCU_RS08790	COG4221	oxidoreductase activity
LCU_RS08795	COG0308	aminopeptidase N
LCU_RS08800	COG0561	phosphatase activity
LCU_RS08805	COG2723	6-phospho-beta-galactosidase activity
LCU_RS08825	COG0789	Transcriptional regulator
LCU_RS08840	COG2826	transposase and inactivated derivatives, IS30 family
LCU_RS08850	COG2826	transposase and inactivated derivatives, IS30 family
LCU_RS08890	COG1914	H( )-stimulated, divalent metal cation uptake system
LCU_RS08915	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
LCU_RS08925	COG1957	nucleoside hydrolase
LCU_RS08940	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
LCU_RS08945	COG1695	Transcriptional regulator
LCU_RS08950	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
LCU_RS08970	COG1132	(ABC) transporter
LCU_RS08975	COG3973	AAA domain
LCU_RS08985	COG3973	AAA domain
LCU_RS08995	COG1744	ABC transporter substrate-binding protein PnrA-like
LCU_RS09000	COG3845	ABC transporter
LCU_RS09005	COG4603	Belongs to the binding-protein-dependent transport system permease family
LCU_RS09010	COG1079	Belongs to the binding-protein-dependent transport system permease family
LCU_RS09015	COG2723	6-phospho-beta-galactosidase activity
LCU_RS09020	COG3711	transcriptional antiterminator
LCU_RS09020	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
LCU_RS09025	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LCU_RS09025	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LCU_RS09025	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
LCU_RS09030	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LCU_RS09035	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LCU_RS09040	COG0383	alpha-mannosidase activity
LCU_RS09045	COG2814	Major facilitator Superfamily
LCU_RS09050	COG2365	Tyrosine phosphatase family
LCU_RS09055	COG0516	GMP reductase activity
LCU_RS09055	COG0517	IMP dehydrogenase activity
LCU_RS09065	COG5002	protein histidine kinase activity
LCU_RS09070	COG1686	Belongs to the peptidase S11 family
LCU_RS09075	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
LCU_RS09090	COG1121	(ABC) transporter
LCU_RS09105	COG1316	TRANSCRIPTIONal
LCU_RS09110	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
LCU_RS09120	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
LCU_RS09140	COG2188	Transcriptional regulator
LCU_RS09145	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
LCU_RS09150	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
LCU_RS09155	COG1737	Transcriptional regulator
LCU_RS09160	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
LCU_RS09165	COG1070	Carbohydrate kinase
LCU_RS09185	COG1914	H( )-stimulated, divalent metal cation uptake system
LCU_RS09190	COG1285	pathogenesis
LCU_RS09270	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
LCU_RS09275	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
LCU_RS09295	COG0756	dUTP diphosphatase activity
LCU_RS09300	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
LCU_RS09305	COG4956	integral membrane protein (PIN domain superfamily)
LCU_RS09310	COG0215	cysteine-tRNA ligase activity
LCU_RS09315	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
LCU_RS09320	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LCU_RS09325	COG3688	RNA-binding protein containing a PIN domain
LCU_RS09335	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
LCU_RS09345	COG0488	(ABC) transporter
LCU_RS09355	COG1266	CAAX protease self-immunity
LCU_RS09360	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
LCU_RS09365	COG0459	protein refolding
LCU_RS09380	COG0531	amino acid
LCU_RS09385	COG1692	metallophosphoesterase
LCU_RS09390	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
LCU_RS09400	COG0424	maF-like protein
LCU_RS09410	COG0632	four-way junction helicase activity
LCU_RS09415	COG2255	four-way junction helicase activity
LCU_RS09420	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
LCU_RS09430	COG0343	queuine tRNA-ribosyltransferase activity
LCU_RS09435	COG1862	Preprotein translocase
LCU_RS09440	COG1454	alcohol dehydrogenase
LCU_RS09440	COG1012	belongs to the aldehyde dehydrogenase family
LCU_RS09445	COG1321	iron dependent repressor
LCU_RS09450	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
LCU_RS09455	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
LCU_RS09460	COG4109	DRTGG domain
LCU_RS09465	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
LCU_RS09470	COG0513	Belongs to the DEAD box helicase family
LCU_RS09480	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
LCU_RS09485	COG4472	Bacterial protein of unknown function (DUF965)
LCU_RS09490	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
LCU_RS09495	COG3906	Belongs to the UPF0473 family
LCU_RS09500	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
LCU_RS09505	COG1286	toxin biosynthetic process
LCU_RS09510	COG1193	negative regulation of DNA recombination
LCU_RS09515	COG3118	belongs to the thioredoxin family
LCU_RS09525	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LCU_RS09530	COG1696	Membrane protein involved in D-alanine export
LCU_RS09535	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LCU_RS09540	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
LCU_RS09545	COG1719	4-vinyl reductase, 4VR
LCU_RS09550	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
LCU_RS09555	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
LCU_RS09590	COG0668	transmembrane transport
LCU_RS09605	COG0006	proline dipeptidase activity
LCU_RS09610	COG1609	Transcriptional regulator
LCU_RS09615	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
LCU_RS09620	COG0363	glucosamine-6-phosphate deaminase activity
LCU_RS09635	COG2814	Major facilitator Superfamily
LCU_RS09650	COG2217	Heavy metal translocating P-type atpase
LCU_RS09655	COG0640	Transcriptional regulator
LCU_RS09675	COG0737	Belongs to the 5'-nucleotidase family
LCU_RS09680	COG4470	Protein conserved in bacteria
LCU_RS09685	COG0647	UMP catabolic process
LCU_RS09695	COG0586	Pfam SNARE associated Golgi protein
LCU_RS09700	COG0492	ferredoxin-NADP+ reductase activity
LCU_RS09705	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
LCU_RS09710	COG1940	carbohydrate kinase activity
LCU_RS09715	COG1098	S1 RNA binding domain
LCU_RS09760	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
LCU_RS09765	COG0628	permease
LCU_RS09780	COG1181	Belongs to the D-alanine--D-alanine ligase family
LCU_RS09805	COG3973	AAA domain
LCU_RS09810	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
LCU_RS09815	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
LCU_RS09820	COG0475	glutathione-regulated potassium exporter activity
LCU_RS09820	COG0569	domain protein
LCU_RS09825	COG2267	carboxylic ester hydrolase activity