locus-tag	class	description
LDE01_RS00010	COG0592	DNA-directed DNA polymerase activity
LDE01_RS00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
LDE01_RS00025	COG0187	DNA topoisomerase II activity
LDE01_RS00030	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
LDE01_RS00035	COG0360	Binds together with S18 to 16S ribosomal RNA
LDE01_RS00040	COG0629	single-stranded DNA binding
LDE01_RS00055	COG0359	binds to the 23S rRNA
LDE01_RS00060	COG0305	Participates in initiation and elongation during chromosome replication
LDE01_RS00080	COG1285	pathogenesis
LDE01_RS00110	COG3842	ATPase activity
LDE01_RS00125	COG4619	ABC transporter
LDE01_RS00130	COG0390	transport system, permease component
LDE01_RS00185	COG0702	epimerase
LDE01_RS00190	COG1942	4-Oxalocrotonate Tautomerase
LDE01_RS00230	COG1482	cell wall glycoprotein biosynthetic process
LDE01_RS00250	COG1191	sigma factor activity
LDE01_RS00255	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
LDE01_RS00265	COG0366	Alpha amylase catalytic
LDE01_RS00275	COG0463	Glycosyl transferase, family 2
LDE01_RS00290	COG1307	EDD domain protein, DegV family
LDE01_RS00305	COG0588	phosphoglycerate mutase activity
LDE01_RS00315	COG1268	BioY protein
LDE01_RS00330	COG0708	Exodeoxyribonuclease III
LDE01_RS00345	COG0656	L-ascorbic acid biosynthetic process
LDE01_RS00365	COG2096	Adenosyltransferase
LDE01_RS00370	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LDE01_RS00380	COG0242	peptide deformylase activity
LDE01_RS00395	COG1960	acyl-CoA dehydrogenase activity
LDE01_RS00400	COG1132	(ABC) transporter
LDE01_RS00410	COG1193	negative regulation of DNA recombination
LDE01_RS00425	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
LDE01_RS00435	COG1940	carbohydrate kinase activity
LDE01_RS00440	COG1053	succinate dehydrogenase
LDE01_RS00445	COG0583	DNA-binding transcription factor activity
LDE01_RS00455	COG2814	Major facilitator Superfamily
LDE01_RS00470	COG1635	Involved in the biosynthesis of the thiazole moiety of thiamine. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur
LDE01_RS00475	COG0583	DNA-binding transcription factor activity
LDE01_RS00480	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
LDE01_RS00485	COG0738	Major facilitator superfamily
LDE01_RS00490	COG0710	3-dehydroquinate dehydratase activity
LDE01_RS00515	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
LDE01_RS00520	COG0583	DNA-binding transcription factor activity
LDE01_RS00525	COG1053	succinate dehydrogenase
LDE01_RS00525	COG3976	FMN-binding domain protein
LDE01_RS00580	COG0745	RESPONSE REGULATOR receiver
LDE01_RS00585	COG5002	protein histidine kinase activity
LDE01_RS00600	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
LDE01_RS00605	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LDE01_RS00635	COG1122	ATPase activity
LDE01_RS00640	COG0477	Major facilitator Superfamily
LDE01_RS00650	COG4555	ABC transporter
LDE01_RS00655	COG0501	Belongs to the peptidase M48B family
LDE01_RS00660	COG1704	LemA family
LDE01_RS00665	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
LDE01_RS00690	COG1126	abc transporter atp-binding protein
LDE01_RS00695	COG0765	amino acid transport
LDE01_RS00705	COG3189	MarR family transcriptional regulator
LDE01_RS00710	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
LDE01_RS00720	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LDE01_RS00730	COG0328	RNA-DNA hybrid ribonuclease activity
LDE01_RS00740	COG1216	Glycosyl transferase, family 2
LDE01_RS00745	COG2267	carboxylic ester hydrolase activity
LDE01_RS00750	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
LDE01_RS00765	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
LDE01_RS00795	COG0657	acetylesterase activity
LDE01_RS00795	COG2755	lipolytic protein G-D-S-L family
LDE01_RS00810	COG0366	Alpha amylase catalytic
LDE01_RS00815	COG1609	Transcriptional regulator
LDE01_RS00820	COG0366	Alpha amylase catalytic
LDE01_RS00835	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
LDE01_RS00840	COG3842	ATPase activity
LDE01_RS00850	COG1175	transmembrane transport
LDE01_RS00855	COG3833	ABC-type maltose transport systems, permease component
LDE01_RS00860	COG1501	Belongs to the glycosyl hydrolase 31 family
LDE01_RS00860	COG1501	Belongs to the glycosyl hydrolase 31 family
LDE01_RS00875	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
LDE01_RS00900	COG2365	Tyrosine phosphatase family
LDE01_RS00905	COG0589	response to stress
LDE01_RS00915	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
LDE01_RS00920	COG3639	organic phosphonate transmembrane transporter activity
LDE01_RS00930	COG4166	transmembrane transport
LDE01_RS00945	COG0367	asparagine synthase
LDE01_RS00960	COG0602	queuosine metabolic process
LDE01_RS00965	COG2151	metal-sulfur cluster biosynthetic enzyme
LDE01_RS00975	COG2814	Major facilitator Superfamily
LDE01_RS00980	COG4545	Glutaredoxin-related protein
LDE01_RS00985	COG3590	peptidase
LDE01_RS01030	COG0569	domain protein
LDE01_RS01030	COG0475	glutathione-regulated potassium exporter activity
LDE01_RS01035	COG0673	inositol 2-dehydrogenase activity
LDE01_RS01045	COG0588	phosphoglycerate mutase activity
LDE01_RS01055	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
LDE01_RS01060	COG1368	sulfuric ester hydrolase activity
LDE01_RS01105	COG1418	mRNA catabolic process
LDE01_RS01115	COG4166	transmembrane transport
LDE01_RS01125	COG4166	transmembrane transport
LDE01_RS01130	COG0601	transmembrane transport
LDE01_RS01135	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LDE01_RS01140	COG0444	Belongs to the ABC transporter superfamily
LDE01_RS01145	COG4608	Belongs to the ABC transporter superfamily
LDE01_RS01165	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
LDE01_RS01170	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
LDE01_RS01175	COG0516	GMP reductase activity
LDE01_RS01190	COG2233	PERMEase
LDE01_RS01200	COG0516	GMP reductase activity
LDE01_RS01200	COG0517	IMP dehydrogenase activity
LDE01_RS01210	COG2274	protein secretion by the type I secretion system
LDE01_RS01210	COG3271	cysteine-type peptidase activity
LDE01_RS01220	COG2723	6-phospho-beta-galactosidase activity
LDE01_RS01245	COG0833	amino acid
LDE01_RS01250	COG2040	homocysteine
LDE01_RS01265	COG0252	asparaginase activity
LDE01_RS01270	COG0561	phosphatase activity
LDE01_RS01285	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
LDE01_RS01290	COG1335	isochorismatase
LDE01_RS01340	COG1121	(ABC) transporter
LDE01_RS01365	COG2131	deaminase
LDE01_RS01375	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
LDE01_RS01380	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LDE01_RS01380	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LDE01_RS01385	COG0084	hydrolase, TatD family'
LDE01_RS01405	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
LDE01_RS01420	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
LDE01_RS01425	COG1078	dGTPase activity
LDE01_RS01435	COG3343	RNA polymerase activity
LDE01_RS01440	COG0504	CTP synthase activity
LDE01_RS01445	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
LDE01_RS01455	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
LDE01_RS01470	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
LDE01_RS01485	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
LDE01_RS01490	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
LDE01_RS01515	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
LDE01_RS01520	COG4166	transmembrane transport
LDE01_RS01525	COG2195	Cleaves the N-terminal amino acid of tripeptides
LDE01_RS01530	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
LDE01_RS01535	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
LDE01_RS01545	COG2199	diguanylate cyclase activity
LDE01_RS01580	COG1956	GAF domain-containing protein
LDE01_RS01585	COG0542	response to heat
LDE01_RS01740	COG0563	adenylate kinase activity
LDE01_RS01745	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
LDE01_RS01765	COG0202	RNA polymerase activity
LDE01_RS01785	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
LDE01_RS01795	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
LDE01_RS01800	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
LDE01_RS01820	COG4166	transmembrane transport
LDE01_RS01825	COG1051	belongs to the nudix hydrolase family
LDE01_RS01835	COG1881	PFAM PEBP family protein
LDE01_RS01845	COG0436	Aminotransferase
LDE01_RS01865	COG4166	transmembrane transport
LDE01_RS01880	COG2188	Transcriptional regulator
LDE01_RS01885	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
LDE01_RS01925	COG1131	(ABC) transporter
LDE01_RS01930	COG3091	SprT-like family
LDE01_RS01945	COG1705	Flagellar rod assembly protein muramidase FlgJ
LDE01_RS01960	COG4851	CamS sex pheromone cAM373 precursor
LDE01_RS01980	COG1597	lipid kinase activity
LDE01_RS01990	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
LDE01_RS02045	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
LDE01_RS02080	COG3759	membrane
LDE01_RS02085	COG1522	sequence-specific DNA binding
LDE01_RS02090	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
LDE01_RS02100	COG2213	PTS system mannitol-specific
LDE01_RS02105	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
LDE01_RS02115	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
LDE01_RS02120	COG0488	(ABC) transporter
LDE01_RS02150	COG0670	Belongs to the BI1 family
LDE01_RS02160	COG4690	dipeptidase activity
LDE01_RS02175	COG0572	uridine kinase
LDE01_RS02180	COG0572	uridine kinase
LDE01_RS02190	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LDE01_RS02195	COG0765	amino acid transport
LDE01_RS02200	COG0765	amino acid transport
LDE01_RS02205	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LDE01_RS02215	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
LDE01_RS02245	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
LDE01_RS02260	COG2188	Transcriptional regulator
LDE01_RS02275	COG1253	flavin adenine dinucleotide binding
LDE01_RS02285	COG0531	amino acid
LDE01_RS02300	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
LDE01_RS02340	COG0531	amino acid
LDE01_RS02350	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
LDE01_RS02360	COG0716	FMN binding
LDE01_RS02365	COG0024	Methionine aminopeptidase
LDE01_RS02370	COG1295	ribonuclease BN
LDE01_RS02375	COG1210	Utp--glucose-1-phosphate uridylyltransferase
LDE01_RS02390	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
LDE01_RS02425	COG2132	Multicopper oxidase
LDE01_RS02435	COG0542	response to heat
LDE01_RS02445	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
LDE01_RS02455	COG1393	Belongs to the ArsC family
LDE01_RS02460	COG4862	establishment of competence for transformation
LDE01_RS02465	COG0632	four-way junction helicase activity
LDE01_RS02490	COG2357	RelA SpoT domain protein
LDE01_RS02500	COG0564	pseudouridine synthase activity
LDE01_RS02515	COG2706	6-phosphogluconolactonase activity
LDE01_RS02525	COG0628	permease
LDE01_RS02540	COG1280	lysine exporter protein (LysE YggA)
LDE01_RS02540	COG1674	ftsk spoiiie
LDE01_RS02555	COG1028	Short-chain dehydrogenase reductase Sdr
LDE01_RS02560	COG1426	Protein conserved in bacteria
LDE01_RS02565	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
LDE01_RS02580	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
LDE01_RS02585	COG0632	four-way junction helicase activity
LDE01_RS02590	COG1739	Uncharacterized protein family UPF0029
LDE01_RS02595	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
LDE01_RS02610	COG0653	protein targeting
LDE01_RS02625	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
LDE01_RS02635	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
LDE01_RS02640	COG0492	ferredoxin-NADP+ reductase activity
LDE01_RS02645	COG0556	nucleotide-excision repair
LDE01_RS02650	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
LDE01_RS02675	COG0391	Required for morphogenesis under gluconeogenic growth conditions
LDE01_RS02705	COG4120	Belongs to the binding-protein-dependent transport system permease family
LDE01_RS02755	COG0561	phosphatase activity
LDE01_RS02760	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
LDE01_RS02765	COG0280	phosphate acetyltransferase
LDE01_RS02770	COG0802	atpase or kinase
LDE01_RS02785	COG3842	ATPase activity
LDE01_RS02795	COG1177	transmembrane transport
LDE01_RS02825	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
LDE01_RS02840	COG2217	Heavy metal translocating P-type atpase
LDE01_RS02845	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
LDE01_RS02850	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
LDE01_RS02860	COG3706	GGDEF domain
LDE01_RS02870	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
LDE01_RS02880	COG0531	amino acid
LDE01_RS02895	COG0803	Belongs to the bacterial solute-binding protein 9 family
LDE01_RS02920	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
LDE01_RS02925	COG1459	type II secretion system
LDE01_RS02950	COG0827	DNA restriction-modification system
LDE01_RS02965	COG0745	RESPONSE REGULATOR receiver
LDE01_RS02970	COG5002	protein histidine kinase activity
LDE01_RS02970	COG3850	Histidine kinase
LDE01_RS02975	COG4372	Transposase
LDE01_RS02995	COG1368	sulfuric ester hydrolase activity
LDE01_RS03005	COG0166	Belongs to the GPI family
LDE01_RS03025	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
LDE01_RS03035	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
LDE01_RS03040	COG1435	thymidine kinase activity
LDE01_RS03050	COG2890	protein-(glutamine-N5) methyltransferase activity
LDE01_RS03055	COG0009	L-threonylcarbamoyladenylate synthase
LDE01_RS03065	COG0356	it plays a direct role in the translocation of protons across the membrane
LDE01_RS03070	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
LDE01_RS03085	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
LDE01_RS03110	COG1077	Cell shape determining protein MreB Mrl
LDE01_RS03115	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
LDE01_RS03125	COG0772	Belongs to the SEDS family
LDE01_RS03140	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
LDE01_RS03170	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
LDE01_RS03175	COG1104	cysteine desulfurase activity
LDE01_RS03185	COG1187	pseudouridine synthase activity
LDE01_RS03190	COG0525	valine-tRNA ligase activity
LDE01_RS03200	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
LDE01_RS03205	COG2003	Belongs to the UPF0758 family
LDE01_RS03210	COG1077	Cell shape determining protein MreB Mrl
LDE01_RS03250	COG0768	penicillin binding
LDE01_RS03270	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
LDE01_RS03275	COG0849	cell division
LDE01_RS03280	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
LDE01_RS03290	COG0762	integral membrane protein
LDE01_RS03305	COG1278	Cold shock
LDE01_RS03320	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
LDE01_RS03325	COG1104	cysteine desulfurase activity
LDE01_RS03335	COG0482	sulfurtransferase activity
LDE01_RS03340	COG0406	alpha-ribazole phosphatase activity
LDE01_RS03350	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
LDE01_RS03370	COG0242	peptide deformylase activity
LDE01_RS03375	COG1217	gtp-binding protein TYPA
LDE01_RS03380	COG0772	Belongs to the SEDS family
LDE01_RS03390	COG0742	ribosomal rna small subunit methyltransferase
LDE01_RS03395	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
LDE01_RS03400	COG3480	Lon protease (S16) C-terminal proteolytic domain
LDE01_RS03405	COG1555	photosystem II stabilization
LDE01_RS03410	COG2333	competence protein COMEC
LDE01_RS03410	COG0658	competence protein
LDE01_RS03415	COG1466	dna polymerase III delta subunit
LDE01_RS03450	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
LDE01_RS03470	COG4166	transmembrane transport
LDE01_RS03480	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LDE01_RS03490	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
LDE01_RS03495	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
LDE01_RS03515	COG1053	succinate dehydrogenase
LDE01_RS03545	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LDE01_RS03550	COG0583	DNA-binding transcription factor activity
LDE01_RS03555	COG0018	arginyl-trna synthetase
LDE01_RS03570	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
LDE01_RS03580	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LDE01_RS03585	COG0514	ATP-dependent DNA helicase (RecQ)
LDE01_RS03590	COG1957	nucleoside hydrolase
LDE01_RS03605	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
LDE01_RS03605	COG2755	lipolytic protein G-D-S-L family
LDE01_RS03615	COG0300	oxidoreductase activity
LDE01_RS03625	COG0737	Belongs to the 5'-nucleotidase family
LDE01_RS03635	COG4475	Protein of unknown function (DUF436)
LDE01_RS03645	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
LDE01_RS03650	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
LDE01_RS03655	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
LDE01_RS03665	COG0587	DNA-directed DNA polymerase activity
LDE01_RS03695	COG2996	Protein conserved in bacteria
LDE01_RS03705	COG0456	acetyltransferase
LDE01_RS03715	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
LDE01_RS03720	COG1187	pseudouridine synthase activity
LDE01_RS03725	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
LDE01_RS03740	COG0539	negative regulation of cytoplasmic translation
LDE01_RS03770	COG0583	DNA-binding transcription factor activity
LDE01_RS03800	COG0137	argininosuccinate synthase activity
LDE01_RS03805	COG0165	Argininosuccinate lyase
LDE01_RS03855	COG2217	Heavy metal translocating P-type atpase
LDE01_RS03900	COG0431	NADPH-dependent FMN reductase
LDE01_RS03900	COG1053	succinate dehydrogenase
LDE01_RS03900	COG3976	FMN-binding domain protein
LDE01_RS03905	COG1053	succinate dehydrogenase
LDE01_RS03910	COG2357	RelA SpoT domain protein
LDE01_RS03915	COG0745	RESPONSE REGULATOR receiver
LDE01_RS03920	COG5002	protein histidine kinase activity
LDE01_RS03930	COG1518	maintenance of DNA repeat elements
LDE01_RS03945	COG0183	Belongs to the thiolase family
LDE01_RS03955	COG3425	synthase
LDE01_RS03965	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
LDE01_RS03970	COG2264	protein methyltransferase activity
LDE01_RS03975	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
LDE01_RS03980	COG1490	D-aminoacyl-tRNA deacylase activity
LDE01_RS03990	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
LDE01_RS04015	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LDE01_RS04020	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
LDE01_RS04025	COG1028	Short-chain dehydrogenase reductase Sdr
LDE01_RS04030	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
LDE01_RS04045	COG0439	Biotin carboxylase
LDE01_RS04055	COG0825	malonyl-CoA metabolic process
LDE01_RS04060	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
LDE01_RS04090	COG1012	belongs to the aldehyde dehydrogenase family
LDE01_RS04090	COG1454	alcohol dehydrogenase
LDE01_RS04115	COG0367	asparagine synthase
LDE01_RS04195	COG4166	transmembrane transport
LDE01_RS04215	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
LDE01_RS04220	COG0573	inorganic phosphate transmembrane transporter activity
LDE01_RS04225	COG0581	inorganic phosphate transmembrane transporter activity
LDE01_RS04230	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
LDE01_RS04235	COG0704	Plays a role in the regulation of phosphate uptake
LDE01_RS04245	COG5002	protein histidine kinase activity
LDE01_RS04250	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
LDE01_RS04255	COG0488	(ABC) transporter
LDE01_RS04290	COG0561	phosphatase activity
LDE01_RS04310	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
LDE01_RS04315	COG0187	DNA topoisomerase II activity
LDE01_RS04320	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
LDE01_RS04325	COG1227	inorganic diphosphatase activity
LDE01_RS04330	COG1304	FMN binding
LDE01_RS04345	COG0083	homoserine kinase activity
LDE01_RS04350	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
LDE01_RS04355	COG1074	ATP-dependent DNA helicase activity
LDE01_RS04360	COG1199	ATP-dependent helicase activity
LDE01_RS04360	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
LDE01_RS04370	COG0017	Asparaginyl-tRNA synthetase
LDE01_RS04375	COG3935	DnaD domain protein
LDE01_RS04380	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
LDE01_RS04385	COG0561	phosphatase activity
LDE01_RS04400	COG0823	Involved in the tonB-independent uptake of proteins
LDE01_RS04400	COG4946	Tricorn protease homolog
LDE01_RS04400	COG1506	peptidase
LDE01_RS04405	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
LDE01_RS04420	COG3599	regulation of cell shape
LDE01_RS04430	COG0116	Belongs to the methyltransferase superfamily
LDE01_RS04445	COG2759	Belongs to the formate--tetrahydrofolate ligase family
LDE01_RS04455	COG0564	pseudouridine synthase activity
LDE01_RS04460	COG0505	Belongs to the CarA family
LDE01_RS04465	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
LDE01_RS04470	COG3830	Belongs to the UPF0237 family
LDE01_RS04480	COG1293	RNA-binding protein homologous to eukaryotic snRNP
LDE01_RS04485	COG1307	EDD domain protein, DegV family
LDE01_RS04500	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
LDE01_RS04505	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
LDE01_RS04510	COG0406	alpha-ribazole phosphatase activity
LDE01_RS04540	COG4974	Belongs to the 'phage' integrase family
LDE01_RS04545	COG1929	Belongs to the glycerate kinase type-1 family
LDE01_RS04600	COG0546	phosphoglycolate phosphatase activity
LDE01_RS04615	COG2070	2-Nitropropane dioxygenase
LDE01_RS04685	COG1132	(ABC) transporter
LDE01_RS04690	COG1132	(ABC) transporter
LDE01_RS04700	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LDE01_RS04715	COG1132	(ABC) transporter
LDE01_RS04720	COG1132	(ABC) transporter
LDE01_RS04725	COG0702	epimerase
LDE01_RS04745	COG2267	carboxylic ester hydrolase activity
LDE01_RS04750	COG4166	transmembrane transport
LDE01_RS04755	COG2226	methyltransferase
LDE01_RS04760	COG1132	(ABC) transporter
LDE01_RS04775	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
LDE01_RS04785	COG0582	viral genome integration into host DNA
LDE01_RS04815	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
LDE01_RS04825	COG1136	(ABC) transporter
LDE01_RS04840	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LDE01_RS04845	COG0431	NADPH-dependent FMN reductase
LDE01_RS04845	COG1053	succinate dehydrogenase
LDE01_RS04845	COG3976	FMN-binding domain protein
LDE01_RS04880	COG0436	Aminotransferase
LDE01_RS04885	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
LDE01_RS04890	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
LDE01_RS04895	COG1473	amidohydrolase
LDE01_RS04900	COG2171	N-acyltransferase activity
LDE01_RS04905	COG0527	aspartate kinase activity
LDE01_RS04925	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LDE01_RS04945	COG2315	Protein conserved in bacteria
LDE01_RS04950	COG1434	Gram-negative-bacterium-type cell wall biogenesis
LDE01_RS04970	COG1619	proteins homologs of microcin C7 resistance protein MccF
LDE01_RS04975	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
LDE01_RS04975	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
LDE01_RS05000	COG2339	peptidase activity
LDE01_RS05015	COG1174	glycine betaine transport
LDE01_RS05025	COG1959	2 iron, 2 sulfur cluster binding
LDE01_RS05035	COG0501	Belongs to the peptidase M48B family
LDE01_RS05045	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
LDE01_RS05065	COG0586	Pfam SNARE associated Golgi protein
LDE01_RS05075	COG0017	Asparaginyl-tRNA synthetase
LDE01_RS05080	COG0110	maltose O-acetyltransferase activity
LDE01_RS05100	COG2195	Cleaves the N-terminal amino acid of tripeptides
LDE01_RS05105	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
LDE01_RS05110	COG2384	SAM-dependent methyltransferase
LDE01_RS05135	COG1053	succinate dehydrogenase
LDE01_RS05155	COG0823	Involved in the tonB-independent uptake of proteins
LDE01_RS05155	COG1506	peptidase
LDE01_RS05155	COG4946	Tricorn protease homolog
LDE01_RS05170	COG5001	Diguanylate cyclase
LDE01_RS05175	COG0393	Putative heavy-metal-binding
LDE01_RS05190	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
LDE01_RS05195	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
LDE01_RS05200	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
LDE01_RS05205	COG0358	DNA primase activity
LDE01_RS05215	COG0752	glycyl-tRNA synthetase alpha subunit
LDE01_RS05220	COG1381	Involved in DNA repair and RecF pathway recombination
LDE01_RS05230	COG0295	cytidine deaminase activity
LDE01_RS05240	COG1702	phosphate starvation-inducible protein PhoH
LDE01_RS05245	COG0828	Belongs to the bacterial ribosomal protein bS21 family
LDE01_RS05260	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
LDE01_RS05270	COG0436	Aminotransferase
LDE01_RS05320	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
LDE01_RS05325	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
LDE01_RS05330	COG0758	DNA mediated transformation
LDE01_RS05335	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
LDE01_RS05340	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
LDE01_RS05350	COG1307	EDD domain protein, DegV family
LDE01_RS05355	COG1272	protein, Hemolysin III
LDE01_RS05360	COG0617	tRNA 3'-terminal CCA addition
LDE01_RS05395	COG1132	(ABC) transporter
LDE01_RS05400	COG1132	(ABC) transporter
LDE01_RS05405	COG0583	DNA-binding transcription factor activity
LDE01_RS05420	COG1307	EDD domain protein, DegV family
LDE01_RS05435	COG1126	abc transporter atp-binding protein
LDE01_RS05440	COG0765	amino acid transport
LDE01_RS05445	COG0583	DNA-binding transcription factor activity
LDE01_RS05455	COG1316	TRANSCRIPTIONal
LDE01_RS05460	COG0628	permease
LDE01_RS05465	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
LDE01_RS05475	COG0640	Transcriptional regulator
LDE01_RS05485	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
LDE01_RS05485	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
LDE01_RS05490	COG3764	Sortase (surface protein transpeptidase)
LDE01_RS05520	COG0196	riboflavin kinase activity
LDE01_RS05525	COG0582	viral genome integration into host DNA
LDE01_RS05600	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
LDE01_RS05610	COG2740	Nucleic-acid-binding protein implicated in transcription termination
LDE01_RS05615	COG0195	Participates in both transcription termination and antitermination
LDE01_RS05635	COG0750	zinc metalloprotease
LDE01_RS05640	COG4589	Belongs to the CDS family
LDE01_RS05645	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
LDE01_RS05650	COG0233	cytoplasmic translational termination
LDE01_RS05670	COG2827	Endonuclease containing a URI domain
LDE01_RS05675	COG0204	Acyl-transferase
LDE01_RS05680	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
LDE01_RS05685	COG0527	aspartate kinase activity
LDE01_RS05690	COG0460	homoserine dehydrogenase
LDE01_RS05705	COG1132	(ABC) transporter
LDE01_RS05710	COG1132	(ABC) transporter
LDE01_RS05715	COG3763	UPF0154 protein
LDE01_RS05720	COG4224	UPF0291 protein
LDE01_RS05735	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LDE01_RS05745	COG1111	helicase
LDE01_RS05745	COG1205	dead DEAH box helicase
LDE01_RS05765	COG0737	Belongs to the 5'-nucleotidase family
LDE01_RS05795	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
LDE01_RS05810	COG0552	protein localization to endoplasmic reticulum
LDE01_RS05815	COG1196	nuclear chromosome segregation
LDE01_RS05820	COG0571	ribonuclease III activity
LDE01_RS05835	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LDE01_RS05840	COG0601	transmembrane transport
LDE01_RS05845	COG4608	Belongs to the ABC transporter superfamily
LDE01_RS05855	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LDE01_RS05860	COG0416	fatty acid biosynthetic process
LDE01_RS05865	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
LDE01_RS05870	COG1461	Dihydroxyacetone kinase
LDE01_RS05910	COG1162	GTPase activity
LDE01_RS05915	COG2815	serine threonine protein kinase
LDE01_RS05915	COG0515	serine threonine protein kinase
LDE01_RS05925	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
LDE01_RS05925	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
LDE01_RS05935	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
LDE01_RS05945	COG0194	GDP metabolic process
LDE01_RS05960	COG0497	DNA recombination
LDE01_RS05965	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
LDE01_RS05975	COG1722	exodeoxyribonuclease VII activity
LDE01_RS05990	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
LDE01_RS05995	COG1302	Protein conserved in bacteria
LDE01_RS06000	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
LDE01_RS06005	COG0006	proline dipeptidase activity
LDE01_RS06025	COG0626	cystathionine gamma-synthase activity
LDE01_RS06030	COG0626	cystathionine gamma-synthase activity
LDE01_RS06060	COG0151	Belongs to the GarS family
LDE01_RS06070	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
LDE01_RS06090	COG0047	phosphoribosylformylglycinamidine synthase activity
LDE01_RS06095	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
LDE01_RS06100	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
LDE01_RS06105	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
LDE01_RS06110	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
LDE01_RS06115	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
LDE01_RS06140	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
LDE01_RS06165	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
LDE01_RS06180	COG1307	EDD domain protein, DegV family
LDE01_RS06225	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
LDE01_RS06240	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
LDE01_RS06250	COG0768	penicillin binding
LDE01_RS06265	COG0072	phenylalanine-tRNA ligase activity
LDE01_RS06270	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
LDE01_RS06275	COG1733	regulation of RNA biosynthetic process
LDE01_RS06280	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LDE01_RS06285	COG1254	Belongs to the acylphosphatase family
LDE01_RS06290	COG0706	membrane insertase activity
LDE01_RS06295	COG5002	protein histidine kinase activity
LDE01_RS06300	COG0745	RESPONSE REGULATOR receiver
LDE01_RS06315	COG0799	negative regulation of ribosome biogenesis
LDE01_RS06325	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
LDE01_RS06330	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
LDE01_RS06345	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
LDE01_RS06365	COG1484	DNA-dependent DNA replication
LDE01_RS06380	COG0237	dephospho-CoA kinase activity
LDE01_RS06385	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
LDE01_RS06390	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
LDE01_RS06390	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
LDE01_RS06430	COG2217	Heavy metal translocating P-type atpase
LDE01_RS06455	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LDE01_RS06460	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LDE01_RS06475	COG1131	(ABC) transporter
LDE01_RS06480	COG0537	adenosine 5'-monophosphoramidase activity
LDE01_RS06490	COG0167	dihydroorotate dehydrogenase activity
LDE01_RS06500	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
LDE01_RS06505	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
LDE01_RS06515	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
LDE01_RS06520	COG3481	metal-dependent phosphohydrolase, HD sub domain
LDE01_RS06525	COG4717	serine-type aminopeptidase activity
LDE01_RS06530	COG0420	3'-5' exonuclease activity
LDE01_RS06540	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
LDE01_RS06545	COG0564	pseudouridine synthase activity
LDE01_RS06555	COG1376	ErfK ybiS ycfS ynhG family protein
LDE01_RS06565	COG0366	Alpha amylase catalytic
LDE01_RS06565	COG5263	repeat protein
LDE01_RS06580	COG1376	ErfK ybiS ycfS ynhG family protein
LDE01_RS06585	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
LDE01_RS06590	COG1686	Belongs to the peptidase S11 family
LDE01_RS06600	COG0028	Belongs to the TPP enzyme family
LDE01_RS06610	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
LDE01_RS06610	COG0574	Belongs to the PEP-utilizing enzyme family
LDE01_RS06615	COG2244	polysaccharide biosynthetic process
LDE01_RS06625	COG0671	phosphoesterase, PA-phosphatase related
LDE01_RS06630	COG0477	Major facilitator Superfamily
LDE01_RS06635	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
LDE01_RS06695	COG0586	Pfam SNARE associated Golgi protein
LDE01_RS06705	COG0647	UMP catabolic process
LDE01_RS06715	COG0737	Belongs to the 5'-nucleotidase family
LDE01_RS06750	COG0668	transmembrane transport
LDE01_RS06755	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
LDE01_RS06765	COG3118	belongs to the thioredoxin family
LDE01_RS06770	COG1193	negative regulation of DNA recombination
LDE01_RS06795	COG0513	Belongs to the DEAD box helicase family
LDE01_RS06800	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
LDE01_RS06805	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
LDE01_RS06810	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
LDE01_RS06825	COG0632	four-way junction helicase activity
LDE01_RS06830	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
LDE01_RS06850	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
LDE01_RS06855	COG0488	(ABC) transporter
LDE01_RS06870	COG1214	PFAM Peptidase M22, glycoprotease
LDE01_RS06885	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
LDE01_RS06895	COG0470	DNA polymerase III
LDE01_RS06900	COG3870	Protein conserved in bacteria
LDE01_RS06920	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
LDE01_RS06925	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
LDE01_RS06935	COG0590	tRNA wobble adenosine to inosine editing
LDE01_RS06940	COG2813	Specifically methylates the guanine in position
LDE01_RS06945	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
LDE01_RS06980	COG3867	Arabinogalactan endo-beta-1,4-galactanase
LDE01_RS06995	COG1472	Belongs to the glycosyl hydrolase 3 family
LDE01_RS07075	COG0004	ammonium transporteR
LDE01_RS07080	COG1215	transferase activity, transferring glycosyl groups
LDE01_RS07095	COG0250	Participates in transcription elongation, termination and antitermination
LDE01_RS07110	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
LDE01_RS07135	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
LDE01_RS07150	COG4166	transmembrane transport
LDE01_RS07160	COG0583	DNA-binding transcription factor activity
LDE01_RS07180	COG1131	(ABC) transporter
LDE01_RS07185	COG1725	Transcriptional regulator
LDE01_RS07190	COG4166	transmembrane transport
LDE01_RS07195	COG0494	nUDIX hydrolase
LDE01_RS07220	COG1454	alcohol dehydrogenase
LDE01_RS07220	COG1012	belongs to the aldehyde dehydrogenase family
LDE01_RS07230	COG1122	ATPase activity
LDE01_RS07245	COG1113	amino acid transport
LDE01_RS07255	COG1131	(ABC) transporter
LDE01_RS07315	COG1442	glycosyl transferase family 8
LDE01_RS07325	COG0756	dUTP diphosphatase activity
LDE01_RS07350	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
LDE01_RS07355	COG0588	phosphoglycerate mutase activity
LDE01_RS07370	COG0588	phosphoglycerate mutase activity
LDE01_RS07390	COG4948	Mandelate Racemase Muconate Lactonizing
LDE01_RS07400	COG1737	Transcriptional regulator
LDE01_RS07410	COG1113	amino acid transport
LDE01_RS07420	COG0698	ribose 5-phosphate isomerase
LDE01_RS07440	COG1105	Belongs to the carbohydrate kinase PfkB family
LDE01_RS07475	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
LDE01_RS07475	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
LDE01_RS07485	COG1447	Phosphotransferase system cellobiose-specific component IIA
LDE01_RS07490	COG1027	Aspartate ammonia-lyase
LDE01_RS07495	COG2017	converts alpha-aldose to the beta-anomer
LDE01_RS07500	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
LDE01_RS07505	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
LDE01_RS07535	COG0083	homoserine kinase activity
LDE01_RS07580	COG1621	beta-fructofuranosidase activity
LDE01_RS07585	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LDE01_RS07585	COG2190	(PTS) system
LDE01_RS07585	COG1263	PTS System
LDE01_RS07590	COG0205	6-phosphofructokinase activity
LDE01_RS07595	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
LDE01_RS07640	COG2223	nitrite transmembrane transporter activity
LDE01_RS07660	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
LDE01_RS07670	COG1113	amino acid transport
LDE01_RS07685	COG3716	PTS system mannose fructose sorbose family IID component
LDE01_RS07690	COG3715	PTS system
LDE01_RS07705	COG1757	Na H antiporter
LDE01_RS07730	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LDE01_RS07730	COG2190	(PTS) system
LDE01_RS07730	COG1263	PTS System
LDE01_RS07740	COG1737	Transcriptional regulator
LDE01_RS07745	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LDE01_RS07745	COG1263	PTS System
LDE01_RS07760	COG0557	exoribonuclease II activity
LDE01_RS07770	COG1368	sulfuric ester hydrolase activity
LDE01_RS07780	COG0438	transferase activity, transferring glycosyl groups
LDE01_RS07785	COG0438	transferase activity, transferring glycosyl groups
LDE01_RS07925	COG2235	arginine
LDE01_RS07935	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
LDE01_RS08020	COG0505	Belongs to the CarA family
LDE01_RS08035	COG1012	belongs to the aldehyde dehydrogenase family
LDE01_RS08045	COG2409	Drug exporters of the RND superfamily
LDE01_RS08045	COG1033	growth of symbiont in host cell
LDE01_RS08045	COG1033	growth of symbiont in host cell
LDE01_RS08045	COG2409	Drug exporters of the RND superfamily
LDE01_RS08115	COG1132	(ABC) transporter
LDE01_RS08125	COG2267	carboxylic ester hydrolase activity
LDE01_RS08135	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
LDE01_RS08140	COG1072	(Pantothenic acid kinase))
LDE01_RS08160	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LDE01_RS08170	COG1126	abc transporter atp-binding protein
LDE01_RS08175	COG0765	amino acid transport
LDE01_RS08180	COG3973	AAA domain
LDE01_RS08200	COG0584	glycerophosphoryl diester phosphodiesterase
LDE01_RS08220	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
LDE01_RS08235	COG2246	polysaccharide biosynthetic process
LDE01_RS08245	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
LDE01_RS08265	COG1215	transferase activity, transferring glycosyl groups
LDE01_RS08280	COG0438	transferase activity, transferring glycosyl groups
LDE01_RS08285	COG1215	transferase activity, transferring glycosyl groups
LDE01_RS08295	COG1442	glycosyl transferase family 8
LDE01_RS08295	COG1216	Glycosyl transferase, family 2
LDE01_RS08330	COG0562	UDP-galactopyranose mutase
LDE01_RS08340	COG1316	TRANSCRIPTIONal
LDE01_RS08345	COG1316	TRANSCRIPTIONal
LDE01_RS08365	COG1396	sequence-specific DNA binding
LDE01_RS08370	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
LDE01_RS08405	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LDE01_RS08405	COG1263	PTS System
LDE01_RS08405	COG2190	(PTS) system
LDE01_RS08410	COG2188	Transcriptional regulator
LDE01_RS08415	COG0366	Alpha amylase catalytic
LDE01_RS08430	COG1116	anion transmembrane transporter activity
LDE01_RS08435	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
LDE01_RS08445	COG1091	dTDP-4-dehydrorhamnose reductase activity
LDE01_RS08450	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
LDE01_RS08460	COG1088	dTDP-glucose 4,6-dehydratase activity
LDE01_RS08475	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
LDE01_RS08480	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
LDE01_RS08485	COG1461	Dihydroxyacetone kinase
LDE01_RS08490	COG2376	Dihydroxyacetone kinase
LDE01_RS08545	COG0697	spore germination
LDE01_RS08570	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
LDE01_RS08575	COG1213	nucleotidyl transferase
LDE01_RS08580	COG3475	LICD family
LDE01_RS08620	COG4372	Transposase
LDE01_RS08660	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
LDE01_RS08665	COG4464	protein tyrosine phosphatase activity
LDE01_RS08670	COG0489	protein tyrosine kinase activity
LDE01_RS08680	COG1316	TRANSCRIPTIONal
LDE01_RS08705	COG1523	belongs to the glycosyl hydrolase 13 family
LDE01_RS08710	COG2826	transposase and inactivated derivatives, IS30 family
LDE01_RS08730	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
LDE01_RS08745	COG0791	NLP P60 protein
LDE01_RS08745	COG1388	LysM domain
LDE01_RS08760	COG0791	NLP P60 protein
LDE01_RS08765	COG0791	NLP P60 protein
LDE01_RS08765	COG1388	LysM domain
LDE01_RS08770	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LDE01_RS08780	COG0194	GDP metabolic process
LDE01_RS08830	COG0488	(ABC) transporter
LDE01_RS08840	COG1316	TRANSCRIPTIONal
LDE01_RS08855	COG1304	FMN binding
LDE01_RS08860	COG1620	l-lactate permease
LDE01_RS08875	COG1108	ABC-type Mn2 Zn2 transport systems permease components
LDE01_RS08880	COG1121	(ABC) transporter
LDE01_RS08885	COG0561	phosphatase activity
LDE01_RS08890	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LDE01_RS08890	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LDE01_RS08890	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
LDE01_RS08895	COG1105	Belongs to the carbohydrate kinase PfkB family
LDE01_RS08900	COG1349	DNA-binding transcription factor activity
LDE01_RS08910	COG1794	racemase activity, acting on amino acids and derivatives
LDE01_RS08930	COG1132	(ABC) transporter
LDE01_RS08935	COG1132	(ABC) transporter
LDE01_RS08945	COG0012	GTP binding
LDE01_RS08950	COG4481	Protein conserved in bacteria
LDE01_RS08955	COG1475	DNA binding
LDE01_RS08960	COG1192	Involved in chromosome partitioning
LDE01_RS08990	COG0431	NADPH-dependent FMN reductase
LDE01_RS08995	COG0431	NADPH-dependent FMN reductase
LDE01_RS09010	COG1263	PTS System
LDE01_RS09010	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LDE01_RS09010	COG2190	(PTS) system
LDE01_RS09020	COG3576	pyridoxamine 5-phosphate
LDE01_RS09030	COG1136	(ABC) transporter
LDE01_RS09035	COG0577	efflux transmembrane transporter activity
LDE01_RS09045	COG0277	FAD linked oxidase domain protein
LDE01_RS09050	COG3022	response to hydroperoxide
LDE01_RS09065	COG0778	Nitroreductase
LDE01_RS09100	COG0471	metal ion transport
LDE01_RS09105	COG0114	fumarate hydratase activity
LDE01_RS09135	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
LDE01_RS09140	COG2365	Tyrosine phosphatase family
LDE01_RS09155	COG3442	glutamine amidotransferase
LDE01_RS09185	COG1114	Component of the transport system for branched-chain amino acids
LDE01_RS09190	COG1114	Component of the transport system for branched-chain amino acids
LDE01_RS09205	COG0697	spore germination
LDE01_RS09215	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
LDE01_RS09220	COG0561	phosphatase activity
LDE01_RS09250	COG1309	transcriptional regulator
LDE01_RS09255	COG0577	efflux transmembrane transporter activity
LDE01_RS09255	COG1136	(ABC) transporter
LDE01_RS09275	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
LDE01_RS09285	COG1696	Membrane protein involved in D-alanine export
LDE01_RS09290	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LDE01_RS09335	COG2217	Heavy metal translocating P-type atpase
LDE01_RS09355	COG1744	ABC transporter substrate-binding protein PnrA-like
LDE01_RS09385	COG1744	ABC transporter substrate-binding protein PnrA-like
LDE01_RS09390	COG1744	ABC transporter substrate-binding protein PnrA-like
LDE01_RS09395	COG3845	ABC transporter
LDE01_RS09400	COG4603	Belongs to the binding-protein-dependent transport system permease family
LDE01_RS09405	COG1079	Belongs to the binding-protein-dependent transport system permease family
LDE01_RS09420	COG0446	pyridine nucleotide-disulphide oxidoreductase
LDE01_RS09440	COG0656	L-ascorbic acid biosynthetic process
LDE01_RS09460	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LDE01_RS09480	COG1192	Involved in chromosome partitioning
LDE01_RS09485	COG0582	viral genome integration into host DNA
LDE01_RS09490	COG0783	Belongs to the Dps family
LDE01_RS09510	COG0577	efflux transmembrane transporter activity
LDE01_RS09510	COG1136	(ABC) transporter
LDE01_RS09520	COG1428	Deoxynucleoside kinase
LDE01_RS09525	COG1428	Deoxynucleoside kinase
LDE01_RS09530	COG0765	amino acid transport
LDE01_RS09535	COG1126	abc transporter atp-binding protein
LDE01_RS09540	COG2252	PERMEase
LDE01_RS09565	COG1396	sequence-specific DNA binding
LDE01_RS09600	COG1131	(ABC) transporter
LDE01_RS09620	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
LDE01_RS09625	COG0028	Belongs to the TPP enzyme family
LDE01_RS09630	COG0445	tRNA wobble uridine modification
LDE01_RS09640	COG0706	membrane insertase activity