locus-tag	class	description
LS838_RS00010	COG0592	DNA-directed DNA polymerase activity
LS838_RS00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
LS838_RS00025	COG0187	DNA topoisomerase II activity
LS838_RS00030	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
LS838_RS00035	COG0360	Binds together with S18 to 16S ribosomal RNA
LS838_RS00040	COG0629	single-stranded DNA binding
LS838_RS00045	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
LS838_RS00055	COG0359	binds to the 23S rRNA
LS838_RS00060	COG0305	Participates in initiation and elongation during chromosome replication
LS838_RS00085	COG1285	pathogenesis
LS838_RS00120	COG3842	ATPase activity
LS838_RS00135	COG4619	ABC transporter
LS838_RS00140	COG0390	transport system, permease component
LS838_RS00190	COG0702	epimerase
LS838_RS00195	COG1942	4-Oxalocrotonate Tautomerase
LS838_RS00265	COG2723	6-phospho-beta-galactosidase activity
LS838_RS00275	COG2723	6-phospho-beta-galactosidase activity
LS838_RS00280	COG1482	cell wall glycoprotein biosynthetic process
LS838_RS00300	COG1191	sigma factor activity
LS838_RS00330	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LS838_RS00335	COG1120	ATPase activity
LS838_RS00340	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
LS838_RS00350	COG0366	Alpha amylase catalytic
LS838_RS00365	COG0463	Glycosyl transferase, family 2
LS838_RS00385	COG1307	EDD domain protein, DegV family
LS838_RS00440	COG1268	BioY protein
LS838_RS00455	COG0708	Exodeoxyribonuclease III
LS838_RS00470	COG0656	L-ascorbic acid biosynthetic process
LS838_RS00490	COG2096	Adenosyltransferase
LS838_RS00495	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LS838_RS00500	COG0277	FAD linked oxidase domain protein
LS838_RS00505	COG0242	peptide deformylase activity
LS838_RS00525	COG1960	acyl-CoA dehydrogenase activity
LS838_RS00530	COG1132	(ABC) transporter
LS838_RS00540	COG1193	negative regulation of DNA recombination
LS838_RS00550	COG0583	DNA-binding transcription factor activity
LS838_RS00555	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
LS838_RS00570	COG1940	carbohydrate kinase activity
LS838_RS00580	COG2814	Major facilitator Superfamily
LS838_RS00595	COG1635	Involved in the biosynthesis of the thiazole moiety of thiamine. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur
LS838_RS00600	COG0583	DNA-binding transcription factor activity
LS838_RS00605	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
LS838_RS00610	COG0738	Major facilitator superfamily
LS838_RS00615	COG0710	3-dehydroquinate dehydratase activity
LS838_RS00625	COG2723	6-phospho-beta-galactosidase activity
LS838_RS00630	COG1263	PTS System
LS838_RS00630	COG2190	(PTS) system
LS838_RS00630	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LS838_RS00640	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
LS838_RS00645	COG0583	DNA-binding transcription factor activity
LS838_RS00650	COG1053	succinate dehydrogenase
LS838_RS00650	COG3976	FMN-binding domain protein
LS838_RS00665	COG1373	ATPase (AAA superfamily
LS838_RS00710	COG0745	RESPONSE REGULATOR receiver
LS838_RS00715	COG5002	protein histidine kinase activity
LS838_RS00730	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
LS838_RS00735	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LS838_RS00770	COG1122	ATPase activity
LS838_RS00775	COG0477	Major facilitator Superfamily
LS838_RS00805	COG0501	Belongs to the peptidase M48B family
LS838_RS00810	COG1704	LemA family
LS838_RS00815	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
LS838_RS00830	COG2200	EAL domain
LS838_RS00830	COG2199	diguanylate cyclase activity
LS838_RS00830	COG2203	Gaf domain
LS838_RS00845	COG1126	abc transporter atp-binding protein
LS838_RS00850	COG0765	amino acid transport
LS838_RS00860	COG3189	MarR family transcriptional regulator
LS838_RS00865	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
LS838_RS00875	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LS838_RS00885	COG0328	RNA-DNA hybrid ribonuclease activity
LS838_RS00895	COG1216	Glycosyl transferase, family 2
LS838_RS00900	COG2267	carboxylic ester hydrolase activity
LS838_RS00905	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
LS838_RS00920	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
LS838_RS00950	COG2755	lipolytic protein G-D-S-L family
LS838_RS00950	COG0657	acetylesterase activity
LS838_RS00965	COG0366	Alpha amylase catalytic
LS838_RS00970	COG1609	Transcriptional regulator
LS838_RS00975	COG0366	Alpha amylase catalytic
LS838_RS00990	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
LS838_RS00995	COG3842	ATPase activity
LS838_RS01005	COG1175	transmembrane transport
LS838_RS01010	COG3833	ABC-type maltose transport systems, permease component
LS838_RS01015	COG1501	Belongs to the glycosyl hydrolase 31 family
LS838_RS01015	COG1501	Belongs to the glycosyl hydrolase 31 family
LS838_RS01020	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
LS838_RS01040	COG1136	(ABC) transporter
LS838_RS01040	COG0577	efflux transmembrane transporter activity
LS838_RS01050	COG0745	RESPONSE REGULATOR receiver
LS838_RS01070	COG2365	Tyrosine phosphatase family
LS838_RS01075	COG0589	response to stress
LS838_RS01085	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
LS838_RS01100	COG4166	transmembrane transport
LS838_RS01115	COG0367	asparagine synthase
LS838_RS01130	COG0602	queuosine metabolic process
LS838_RS01135	COG2151	metal-sulfur cluster biosynthetic enzyme
LS838_RS01145	COG2814	Major facilitator Superfamily
LS838_RS01150	COG4545	Glutaredoxin-related protein
LS838_RS01155	COG3590	peptidase
LS838_RS01190	COG1705	Flagellar rod assembly protein muramidase FlgJ
LS838_RS01190	COG3951	Flagellar rod assembly protein muramidase FlgJ
LS838_RS01200	COG0475	glutathione-regulated potassium exporter activity
LS838_RS01200	COG0569	domain protein
LS838_RS01205	COG0673	inositol 2-dehydrogenase activity
LS838_RS01215	COG0588	phosphoglycerate mutase activity
LS838_RS01220	COG1316	TRANSCRIPTIONal
LS838_RS01225	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
LS838_RS01230	COG1368	sulfuric ester hydrolase activity
LS838_RS01235	COG3594	Acyltransferase
LS838_RS01265	COG1418	mRNA catabolic process
LS838_RS01280	COG4166	transmembrane transport
LS838_RS01295	COG4166	transmembrane transport
LS838_RS01305	COG4166	transmembrane transport
LS838_RS01310	COG0601	transmembrane transport
LS838_RS01315	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LS838_RS01320	COG0444	Belongs to the ABC transporter superfamily
LS838_RS01325	COG4608	Belongs to the ABC transporter superfamily
LS838_RS01350	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
LS838_RS01355	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
LS838_RS01360	COG0516	GMP reductase activity
LS838_RS01375	COG2233	PERMEase
LS838_RS01385	COG0516	GMP reductase activity
LS838_RS01385	COG0517	IMP dehydrogenase activity
LS838_RS01395	COG2274	protein secretion by the type I secretion system
LS838_RS01395	COG3271	cysteine-type peptidase activity
LS838_RS01405	COG2723	6-phospho-beta-galactosidase activity
LS838_RS01425	COG0833	amino acid
LS838_RS01430	COG2040	homocysteine
LS838_RS01435	COG0442	prolyl-tRNA aminoacylation
LS838_RS01445	COG0252	asparaginase activity
LS838_RS01450	COG0561	phosphatase activity
LS838_RS01460	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
LS838_RS01465	COG1335	isochorismatase
LS838_RS01500	COG2274	protein secretion by the type I secretion system
LS838_RS01555	COG2131	deaminase
LS838_RS01570	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LS838_RS01570	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LS838_RS01575	COG0084	hydrolase, TatD family'
LS838_RS01595	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
LS838_RS01610	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
LS838_RS01615	COG1078	dGTPase activity
LS838_RS01625	COG3343	RNA polymerase activity
LS838_RS01630	COG0504	CTP synthase activity
LS838_RS01635	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
LS838_RS01645	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
LS838_RS01660	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
LS838_RS01675	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
LS838_RS01680	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
LS838_RS01705	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
LS838_RS01710	COG4166	transmembrane transport
LS838_RS01715	COG2195	Cleaves the N-terminal amino acid of tripeptides
LS838_RS01720	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
LS838_RS01725	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
LS838_RS01745	COG2199	diguanylate cyclase activity
LS838_RS01780	COG1956	GAF domain-containing protein
LS838_RS01785	COG0542	response to heat
LS838_RS01810	COG0561	phosphatase activity
LS838_RS01940	COG0563	adenylate kinase activity
LS838_RS01945	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
LS838_RS01965	COG0202	RNA polymerase activity
LS838_RS01985	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
LS838_RS01995	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
LS838_RS02000	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
LS838_RS02015	COG4166	transmembrane transport
LS838_RS02020	COG1051	belongs to the nudix hydrolase family
LS838_RS02025	COG2814	Major facilitator Superfamily
LS838_RS02030	COG1881	PFAM PEBP family protein
LS838_RS02040	COG0436	Aminotransferase
LS838_RS02060	COG4166	transmembrane transport
LS838_RS02075	COG2188	Transcriptional regulator
LS838_RS02080	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
LS838_RS02125	COG1131	(ABC) transporter
LS838_RS02130	COG3091	SprT-like family
LS838_RS02145	COG1705	Flagellar rod assembly protein muramidase FlgJ
LS838_RS02160	COG4851	CamS sex pheromone cAM373 precursor
LS838_RS02180	COG1597	lipid kinase activity
LS838_RS02190	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
LS838_RS02235	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
LS838_RS02275	COG3759	membrane
LS838_RS02280	COG1522	sequence-specific DNA binding
LS838_RS02285	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
LS838_RS02295	COG2213	PTS system mannitol-specific
LS838_RS02300	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
LS838_RS02310	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
LS838_RS02320	COG0488	(ABC) transporter
LS838_RS02340	COG0670	Belongs to the BI1 family
LS838_RS02350	COG4690	dipeptidase activity
LS838_RS02365	COG0572	uridine kinase
LS838_RS02370	COG0572	uridine kinase
LS838_RS02380	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LS838_RS02385	COG0765	amino acid transport
LS838_RS02390	COG0765	amino acid transport
LS838_RS02395	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LS838_RS02405	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
LS838_RS02430	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
LS838_RS02445	COG2188	Transcriptional regulator
LS838_RS02460	COG1253	flavin adenine dinucleotide binding
LS838_RS02470	COG0531	amino acid
LS838_RS02485	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
LS838_RS02530	COG0531	amino acid
LS838_RS02540	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
LS838_RS02550	COG0716	FMN binding
LS838_RS02555	COG0024	Methionine aminopeptidase
LS838_RS02560	COG1295	ribonuclease BN
LS838_RS02565	COG1210	Utp--glucose-1-phosphate uridylyltransferase
LS838_RS02580	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
LS838_RS02615	COG2132	Multicopper oxidase
LS838_RS02625	COG0542	response to heat
LS838_RS02635	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
LS838_RS02645	COG1393	Belongs to the ArsC family
LS838_RS02650	COG4862	establishment of competence for transformation
LS838_RS02670	COG2357	RelA SpoT domain protein
LS838_RS02680	COG0564	pseudouridine synthase activity
LS838_RS02695	COG2706	6-phosphogluconolactonase activity
LS838_RS02705	COG0628	permease
LS838_RS02720	COG1674	ftsk spoiiie
LS838_RS02720	COG1280	lysine exporter protein (LysE YggA)
LS838_RS02730	COG0612	Peptidase, M16
LS838_RS02735	COG1028	Short-chain dehydrogenase reductase Sdr
LS838_RS02740	COG1426	Protein conserved in bacteria
LS838_RS02745	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
LS838_RS02760	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
LS838_RS02765	COG1739	Uncharacterized protein family UPF0029
LS838_RS02770	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
LS838_RS02785	COG0653	protein targeting
LS838_RS02790	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
LS838_RS02800	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
LS838_RS02810	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
LS838_RS02815	COG0492	ferredoxin-NADP+ reductase activity
LS838_RS02820	COG0556	nucleotide-excision repair
LS838_RS02825	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
LS838_RS02850	COG0391	Required for morphogenesis under gluconeogenic growth conditions
LS838_RS02875	COG4120	Belongs to the binding-protein-dependent transport system permease family
LS838_RS02920	COG0561	phosphatase activity
LS838_RS02925	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
LS838_RS02930	COG0280	phosphate acetyltransferase
LS838_RS02935	COG0802	atpase or kinase
LS838_RS02950	COG3842	ATPase activity
LS838_RS02960	COG1177	transmembrane transport
LS838_RS02990	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
LS838_RS03005	COG2217	Heavy metal translocating P-type atpase
LS838_RS03010	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
LS838_RS03015	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
LS838_RS03025	COG2200	EAL domain
LS838_RS03025	COG2199	diguanylate cyclase activity
LS838_RS03035	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
LS838_RS03045	COG0531	amino acid
LS838_RS03060	COG0803	Belongs to the bacterial solute-binding protein 9 family
LS838_RS03075	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
LS838_RS03080	COG1459	type II secretion system
LS838_RS03105	COG0827	DNA restriction-modification system
LS838_RS03120	COG0745	RESPONSE REGULATOR receiver
LS838_RS03125	COG5002	protein histidine kinase activity
LS838_RS03125	COG3850	Histidine kinase
LS838_RS03130	COG1368	sulfuric ester hydrolase activity
LS838_RS03140	COG0166	Belongs to the GPI family
LS838_RS03145	COG4166	transmembrane transport
LS838_RS03160	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
LS838_RS03170	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
LS838_RS03175	COG1435	thymidine kinase activity
LS838_RS03185	COG2890	protein-(glutamine-N5) methyltransferase activity
LS838_RS03190	COG0009	L-threonylcarbamoyladenylate synthase
LS838_RS03200	COG0356	it plays a direct role in the translocation of protons across the membrane
LS838_RS03205	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
LS838_RS03220	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
LS838_RS03245	COG1077	Cell shape determining protein MreB Mrl
LS838_RS03250	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
LS838_RS03260	COG0772	Belongs to the SEDS family
LS838_RS03275	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
LS838_RS03290	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
LS838_RS03295	COG1104	cysteine desulfurase activity
LS838_RS03305	COG1187	pseudouridine synthase activity
LS838_RS03310	COG0525	valine-tRNA ligase activity
LS838_RS03320	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
LS838_RS03325	COG2003	Belongs to the UPF0758 family
LS838_RS03330	COG1077	Cell shape determining protein MreB Mrl
LS838_RS03370	COG0768	penicillin binding
LS838_RS03390	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
LS838_RS03395	COG0849	cell division
LS838_RS03400	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
LS838_RS03410	COG0762	integral membrane protein
LS838_RS03425	COG1278	Cold shock
LS838_RS03440	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
LS838_RS03445	COG1104	cysteine desulfurase activity
LS838_RS03455	COG0482	sulfurtransferase activity
LS838_RS03460	COG0406	alpha-ribazole phosphatase activity
LS838_RS03470	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
LS838_RS03490	COG0242	peptide deformylase activity
LS838_RS03495	COG1217	gtp-binding protein TYPA
LS838_RS03500	COG0772	Belongs to the SEDS family
LS838_RS03505	COG4471	UPF0298 protein
LS838_RS03510	COG0742	ribosomal rna small subunit methyltransferase
LS838_RS03515	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
LS838_RS03520	COG3480	Lon protease (S16) C-terminal proteolytic domain
LS838_RS03525	COG1555	photosystem II stabilization
LS838_RS03530	COG0658	competence protein
LS838_RS03530	COG2333	competence protein COMEC
LS838_RS03535	COG1466	dna polymerase III delta subunit
LS838_RS03570	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
LS838_RS03590	COG4166	transmembrane transport
LS838_RS03600	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LS838_RS03610	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
LS838_RS03615	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
LS838_RS03625	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
LS838_RS03635	COG1053	succinate dehydrogenase
LS838_RS03665	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LS838_RS03670	COG0583	DNA-binding transcription factor activity
LS838_RS03675	COG0018	arginyl-trna synthetase
LS838_RS03685	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
LS838_RS03695	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LS838_RS03700	COG0514	ATP-dependent DNA helicase (RecQ)
LS838_RS03720	COG2755	lipolytic protein G-D-S-L family
LS838_RS03720	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
LS838_RS03730	COG0300	oxidoreductase activity
LS838_RS03740	COG0737	Belongs to the 5'-nucleotidase family
LS838_RS03755	COG4475	Protein of unknown function (DUF436)
LS838_RS03760	COG2188	Transcriptional regulator
LS838_RS03765	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
LS838_RS03770	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
LS838_RS03775	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
LS838_RS03785	COG0587	DNA-directed DNA polymerase activity
LS838_RS03810	COG2996	Protein conserved in bacteria
LS838_RS03820	COG0456	acetyltransferase
LS838_RS03830	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
LS838_RS03835	COG1187	pseudouridine synthase activity
LS838_RS03840	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
LS838_RS03855	COG0539	negative regulation of cytoplasmic translation
LS838_RS03885	COG0583	DNA-binding transcription factor activity
LS838_RS03905	COG0583	DNA-binding transcription factor activity
LS838_RS03915	COG0137	argininosuccinate synthase activity
LS838_RS03920	COG0165	Argininosuccinate lyase
LS838_RS03955	COG1857	crispr-associated protein
LS838_RS03970	COG1518	maintenance of DNA repeat elements
LS838_RS03975	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
LS838_RS03990	COG2357	RelA SpoT domain protein
LS838_RS03995	COG0745	RESPONSE REGULATOR receiver
LS838_RS04000	COG5002	protein histidine kinase activity
LS838_RS04005	COG3513	CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
LS838_RS04010	COG1518	maintenance of DNA repeat elements
LS838_RS04025	COG0183	Belongs to the thiolase family
LS838_RS04035	COG3425	synthase
LS838_RS04045	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
LS838_RS04050	COG2264	protein methyltransferase activity
LS838_RS04055	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
LS838_RS04060	COG1490	D-aminoacyl-tRNA deacylase activity
LS838_RS04070	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
LS838_RS04085	COG0628	permease
LS838_RS04095	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LS838_RS04100	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
LS838_RS04105	COG1028	Short-chain dehydrogenase reductase Sdr
LS838_RS04110	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
LS838_RS04125	COG0439	Biotin carboxylase
LS838_RS04135	COG0825	malonyl-CoA metabolic process
LS838_RS04140	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
LS838_RS04160	COG0726	polysaccharide deacetylase
LS838_RS04180	COG1454	alcohol dehydrogenase
LS838_RS04180	COG1012	belongs to the aldehyde dehydrogenase family
LS838_RS04215	COG0367	asparagine synthase
LS838_RS04295	COG4166	transmembrane transport
LS838_RS04305	COG5001	Diguanylate cyclase
LS838_RS04315	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
LS838_RS04320	COG0573	inorganic phosphate transmembrane transporter activity
LS838_RS04325	COG0581	inorganic phosphate transmembrane transporter activity
LS838_RS04330	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
LS838_RS04335	COG0704	Plays a role in the regulation of phosphate uptake
LS838_RS04345	COG5002	protein histidine kinase activity
LS838_RS04350	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
LS838_RS04355	COG0488	(ABC) transporter
LS838_RS04375	COG1288	antiporter activity
LS838_RS04380	COG1122	ATPase activity
LS838_RS04385	COG1122	ATPase activity
LS838_RS04400	COG4943	cyclic-guanylate-specific phosphodiesterase activity
LS838_RS04420	COG0561	phosphatase activity
LS838_RS04440	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
LS838_RS04445	COG0187	DNA topoisomerase II activity
LS838_RS04450	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
LS838_RS04455	COG1227	inorganic diphosphatase activity
LS838_RS04460	COG1304	FMN binding
LS838_RS04475	COG0083	homoserine kinase activity
LS838_RS04480	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
LS838_RS04485	COG1074	ATP-dependent DNA helicase activity
LS838_RS04490	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
LS838_RS04490	COG1199	ATP-dependent helicase activity
LS838_RS04500	COG0017	Asparaginyl-tRNA synthetase
LS838_RS04505	COG3935	DnaD domain protein
LS838_RS04510	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
LS838_RS04515	COG0561	phosphatase activity
LS838_RS04530	COG0823	Involved in the tonB-independent uptake of proteins
LS838_RS04530	COG1506	peptidase
LS838_RS04530	COG4946	Tricorn protease homolog
LS838_RS04535	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
LS838_RS04550	COG3599	regulation of cell shape
LS838_RS04560	COG0116	Belongs to the methyltransferase superfamily
LS838_RS04575	COG2759	Belongs to the formate--tetrahydrofolate ligase family
LS838_RS04585	COG0564	pseudouridine synthase activity
LS838_RS04590	COG0505	Belongs to the CarA family
LS838_RS04595	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
LS838_RS04600	COG3830	Belongs to the UPF0237 family
LS838_RS04610	COG1293	RNA-binding protein homologous to eukaryotic snRNP
LS838_RS04615	COG1307	EDD domain protein, DegV family
LS838_RS04630	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
LS838_RS04635	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
LS838_RS04640	COG0406	alpha-ribazole phosphatase activity
LS838_RS04675	COG4974	Belongs to the 'phage' integrase family
LS838_RS04680	COG1929	Belongs to the glycerate kinase type-1 family
LS838_RS04730	COG4166	transmembrane transport
LS838_RS04735	COG4166	transmembrane transport
LS838_RS04740	COG1228	amidohydrolase
LS838_RS04785	COG1053	succinate dehydrogenase
LS838_RS04785	COG1053	succinate dehydrogenase
LS838_RS04800	COG0546	phosphoglycolate phosphatase activity
LS838_RS04815	COG1053	succinate dehydrogenase
LS838_RS04815	COG3976	FMN-binding domain protein
LS838_RS04820	COG0583	DNA-binding transcription factor activity
LS838_RS04840	COG0673	inositol 2-dehydrogenase activity
LS838_RS04845	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
LS838_RS04865	COG1401	restriction endodeoxyribonuclease activity
LS838_RS04870	COG4268	DNA restriction-modification system
LS838_RS04875	COG2070	2-Nitropropane dioxygenase
LS838_RS04910	COG0328	RNA-DNA hybrid ribonuclease activity
LS838_RS04920	COG1132	(ABC) transporter
LS838_RS04925	COG1132	(ABC) transporter
LS838_RS04935	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LS838_RS04945	COG1132	(ABC) transporter
LS838_RS04950	COG1132	(ABC) transporter
LS838_RS04955	COG0702	epimerase
LS838_RS04960	COG0583	DNA-binding transcription factor activity
LS838_RS04985	COG0675	Transposase, IS605 OrfB family
LS838_RS05030	COG1959	2 iron, 2 sulfur cluster binding
LS838_RS05040	COG2267	carboxylic ester hydrolase activity
LS838_RS05045	COG4166	transmembrane transport
LS838_RS05050	COG2226	methyltransferase
LS838_RS05060	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
LS838_RS05070	COG3706	GGDEF domain
LS838_RS05085	COG0582	viral genome integration into host DNA
LS838_RS05115	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
LS838_RS05125	COG1136	(ABC) transporter
LS838_RS05175	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
LS838_RS05180	COG0436	Aminotransferase
LS838_RS05185	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
LS838_RS05190	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
LS838_RS05195	COG1473	amidohydrolase
LS838_RS05200	COG2171	N-acyltransferase activity
LS838_RS05205	COG0527	aspartate kinase activity
LS838_RS05225	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LS838_RS05245	COG2315	Protein conserved in bacteria
LS838_RS05250	COG1434	Gram-negative-bacterium-type cell wall biogenesis
LS838_RS05275	COG1619	proteins homologs of microcin C7 resistance protein MccF
LS838_RS05280	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
LS838_RS05280	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
LS838_RS05305	COG2339	peptidase activity
LS838_RS05320	COG1174	glycine betaine transport
LS838_RS05330	COG1959	2 iron, 2 sulfur cluster binding
LS838_RS05340	COG0501	Belongs to the peptidase M48B family
LS838_RS05365	COG0586	Pfam SNARE associated Golgi protein
LS838_RS05375	COG0017	Asparaginyl-tRNA synthetase
LS838_RS05380	COG0110	maltose O-acetyltransferase activity
LS838_RS05415	COG2195	Cleaves the N-terminal amino acid of tripeptides
LS838_RS05420	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
LS838_RS05425	COG2384	SAM-dependent methyltransferase
LS838_RS05440	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
LS838_RS05445	COG1053	succinate dehydrogenase
LS838_RS05450	COG1609	Transcriptional regulator
LS838_RS05450	COG2207	Transcriptional regulator
LS838_RS05520	COG0823	Involved in the tonB-independent uptake of proteins
LS838_RS05520	COG1506	peptidase
LS838_RS05520	COG4946	Tricorn protease homolog
LS838_RS05535	COG3345	alpha-galactosidase
LS838_RS05555	COG2723	6-phospho-beta-galactosidase activity
LS838_RS05560	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
LS838_RS05565	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
LS838_RS05570	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
LS838_RS05575	COG0358	DNA primase activity
LS838_RS05590	COG1381	Involved in DNA repair and RecF pathway recombination
LS838_RS05600	COG0295	cytidine deaminase activity
LS838_RS05610	COG1702	phosphate starvation-inducible protein PhoH
LS838_RS05615	COG0828	Belongs to the bacterial ribosomal protein bS21 family
LS838_RS05630	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
LS838_RS05640	COG0436	Aminotransferase
LS838_RS05690	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
LS838_RS05695	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
LS838_RS05700	COG0758	DNA mediated transformation
LS838_RS05705	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
LS838_RS05710	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
LS838_RS05720	COG1307	EDD domain protein, DegV family
LS838_RS05725	COG1272	protein, Hemolysin III
LS838_RS05735	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
LS838_RS05760	COG1132	(ABC) transporter
LS838_RS05765	COG1132	(ABC) transporter
LS838_RS05770	COG0583	DNA-binding transcription factor activity
LS838_RS05785	COG1307	EDD domain protein, DegV family
LS838_RS05800	COG1126	abc transporter atp-binding protein
LS838_RS05805	COG0765	amino acid transport
LS838_RS05810	COG0583	DNA-binding transcription factor activity
LS838_RS05825	COG0628	permease
LS838_RS05830	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
LS838_RS05840	COG0640	Transcriptional regulator
LS838_RS05850	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
LS838_RS05850	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
LS838_RS05855	COG3764	Sortase (surface protein transpeptidase)
LS838_RS05885	COG0196	riboflavin kinase activity
LS838_RS05900	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
LS838_RS05910	COG2740	Nucleic-acid-binding protein implicated in transcription termination
LS838_RS05915	COG0195	Participates in both transcription termination and antitermination
LS838_RS05935	COG0750	zinc metalloprotease
LS838_RS05940	COG4589	Belongs to the CDS family
LS838_RS05945	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
LS838_RS05950	COG0233	cytoplasmic translational termination
LS838_RS05970	COG2827	Endonuclease containing a URI domain
LS838_RS05975	COG0204	Acyl-transferase
LS838_RS05980	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
LS838_RS05985	COG0527	aspartate kinase activity
LS838_RS06000	COG1132	(ABC) transporter
LS838_RS06005	COG1132	(ABC) transporter
LS838_RS06010	COG3763	UPF0154 protein
LS838_RS06015	COG4224	UPF0291 protein
LS838_RS06030	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LS838_RS06040	COG1205	dead DEAH box helicase
LS838_RS06040	COG1111	helicase
LS838_RS06055	COG0737	Belongs to the 5'-nucleotidase family
LS838_RS06065	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
LS838_RS06085	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
LS838_RS06090	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
LS838_RS06100	COG0552	protein localization to endoplasmic reticulum
LS838_RS06105	COG1196	nuclear chromosome segregation
LS838_RS06110	COG0571	ribonuclease III activity
LS838_RS06125	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LS838_RS06130	COG0601	transmembrane transport
LS838_RS06135	COG4608	Belongs to the ABC transporter superfamily
LS838_RS06145	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LS838_RS06150	COG0416	fatty acid biosynthetic process
LS838_RS06155	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
LS838_RS06200	COG1162	GTPase activity
LS838_RS06205	COG0515	serine threonine protein kinase
LS838_RS06205	COG2815	serine threonine protein kinase
LS838_RS06215	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
LS838_RS06215	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
LS838_RS06225	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
LS838_RS06235	COG0194	GDP metabolic process
LS838_RS06250	COG0497	DNA recombination
LS838_RS06255	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
LS838_RS06265	COG1722	exodeoxyribonuclease VII activity
LS838_RS06280	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
LS838_RS06285	COG1302	Protein conserved in bacteria
LS838_RS06290	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
LS838_RS06295	COG0006	proline dipeptidase activity
LS838_RS06315	COG0626	cystathionine gamma-synthase activity
LS838_RS06320	COG0626	cystathionine gamma-synthase activity
LS838_RS06350	COG0151	Belongs to the GarS family
LS838_RS06360	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
LS838_RS06380	COG0047	phosphoribosylformylglycinamidine synthase activity
LS838_RS06385	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
LS838_RS06390	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
LS838_RS06395	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
LS838_RS06400	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
LS838_RS06405	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
LS838_RS06435	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
LS838_RS06460	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
LS838_RS06465	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
LS838_RS06475	COG1307	EDD domain protein, DegV family
LS838_RS06480	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
LS838_RS06525	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
LS838_RS06540	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
LS838_RS06550	COG0768	penicillin binding
LS838_RS06565	COG0072	phenylalanine-tRNA ligase activity
LS838_RS06570	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
LS838_RS06575	COG1733	regulation of RNA biosynthetic process
LS838_RS06580	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LS838_RS06585	COG1254	Belongs to the acylphosphatase family
LS838_RS06590	COG0706	membrane insertase activity
LS838_RS06595	COG5002	protein histidine kinase activity
LS838_RS06600	COG0745	RESPONSE REGULATOR receiver
LS838_RS06615	COG0799	negative regulation of ribosome biogenesis
LS838_RS06625	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
LS838_RS06630	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
LS838_RS06645	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
LS838_RS06665	COG2801	Transposase and inactivated derivatives
LS838_RS06680	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
LS838_RS06685	COG1484	DNA-dependent DNA replication
LS838_RS06700	COG0237	dephospho-CoA kinase activity
LS838_RS06715	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
LS838_RS06720	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
LS838_RS06720	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
LS838_RS06730	COG0477	Major facilitator Superfamily
LS838_RS06755	COG1917	Cupin 2, conserved barrel domain protein
LS838_RS06755	COG2207	Transcriptional regulator
LS838_RS06765	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LS838_RS06770	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LS838_RS06785	COG1131	(ABC) transporter
LS838_RS06790	COG0537	adenosine 5'-monophosphoramidase activity
LS838_RS06800	COG0167	dihydroorotate dehydrogenase activity
LS838_RS06810	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
LS838_RS06815	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
LS838_RS06820	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
LS838_RS06825	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
LS838_RS06830	COG3481	metal-dependent phosphohydrolase, HD sub domain
LS838_RS06835	COG4717	serine-type aminopeptidase activity
LS838_RS06840	COG0420	3'-5' exonuclease activity
LS838_RS06850	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
LS838_RS06855	COG0564	pseudouridine synthase activity
LS838_RS06865	COG1376	ErfK ybiS ycfS ynhG family protein
LS838_RS06875	COG0366	Alpha amylase catalytic
LS838_RS06875	COG5263	repeat protein
LS838_RS06895	COG1376	ErfK ybiS ycfS ynhG family protein
LS838_RS06900	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
LS838_RS06905	COG1686	Belongs to the peptidase S11 family
LS838_RS06930	COG2244	polysaccharide biosynthetic process
LS838_RS06940	COG0671	phosphoesterase, PA-phosphatase related
LS838_RS06945	COG0477	Major facilitator Superfamily
LS838_RS06950	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
LS838_RS07010	COG0586	Pfam SNARE associated Golgi protein
LS838_RS07020	COG0647	UMP catabolic process
LS838_RS07065	COG0668	transmembrane transport
LS838_RS07070	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
LS838_RS07080	COG3118	belongs to the thioredoxin family
LS838_RS07085	COG1193	negative regulation of DNA recombination
LS838_RS07110	COG0513	Belongs to the DEAD box helicase family
LS838_RS07115	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
LS838_RS07120	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
LS838_RS07125	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
LS838_RS07140	COG0632	four-way junction helicase activity
LS838_RS07145	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
LS838_RS07165	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
LS838_RS07170	COG0488	(ABC) transporter
LS838_RS07185	COG1214	PFAM Peptidase M22, glycoprotease
LS838_RS07200	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
LS838_RS07210	COG0470	DNA polymerase III
LS838_RS07215	COG3870	Protein conserved in bacteria
LS838_RS07235	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
LS838_RS07240	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
LS838_RS07250	COG0590	tRNA wobble adenosine to inosine editing
LS838_RS07255	COG2813	Specifically methylates the guanine in position
LS838_RS07260	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
LS838_RS07290	COG3867	Arabinogalactan endo-beta-1,4-galactanase
LS838_RS07295	COG3867	Arabinogalactan endo-beta-1,4-galactanase
LS838_RS07300	COG1472	Belongs to the glycosyl hydrolase 3 family
LS838_RS07310	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
LS838_RS07340	COG4166	transmembrane transport
LS838_RS07345	COG1940	carbohydrate kinase activity
LS838_RS07350	COG3842	ATPase activity
LS838_RS07355	COG1621	beta-fructofuranosidase activity
LS838_RS07365	COG1175	transmembrane transport
LS838_RS07370	COG1653	transport
LS838_RS07375	COG1609	Transcriptional regulator
LS838_RS07395	COG0004	ammonium transporteR
LS838_RS07400	COG1215	transferase activity, transferring glycosyl groups
LS838_RS07415	COG0250	Participates in transcription elongation, termination and antitermination
LS838_RS07430	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
LS838_RS07455	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
LS838_RS07470	COG4166	transmembrane transport
LS838_RS07480	COG0583	DNA-binding transcription factor activity
LS838_RS07500	COG1131	(ABC) transporter
LS838_RS07505	COG1725	Transcriptional regulator
LS838_RS07510	COG4166	transmembrane transport
LS838_RS07515	COG0494	nUDIX hydrolase
LS838_RS07535	COG2814	Major facilitator Superfamily
LS838_RS07570	COG1012	belongs to the aldehyde dehydrogenase family
LS838_RS07570	COG1454	alcohol dehydrogenase
LS838_RS07580	COG1122	ATPase activity
LS838_RS07595	COG1113	amino acid transport
LS838_RS07660	COG4943	cyclic-guanylate-specific phosphodiesterase activity
LS838_RS07670	COG1442	glycosyl transferase family 8
LS838_RS07680	COG0756	dUTP diphosphatase activity
LS838_RS07695	COG3976	FMN-binding domain protein
LS838_RS07695	COG1053	succinate dehydrogenase
LS838_RS07695	COG0431	NADPH-dependent FMN reductase
LS838_RS07705	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
LS838_RS07710	COG0588	phosphoglycerate mutase activity
LS838_RS07725	COG0588	phosphoglycerate mutase activity
LS838_RS07745	COG4948	Mandelate Racemase Muconate Lactonizing
LS838_RS07755	COG1737	Transcriptional regulator
LS838_RS07765	COG1113	amino acid transport
LS838_RS07770	COG1349	DNA-binding transcription factor activity
LS838_RS07775	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
LS838_RS07780	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
LS838_RS07785	COG1027	Aspartate ammonia-lyase
LS838_RS07820	COG0083	homoserine kinase activity
LS838_RS07860	COG1621	beta-fructofuranosidase activity
LS838_RS07875	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LS838_RS07875	COG2190	(PTS) system
LS838_RS07875	COG1263	PTS System
LS838_RS07880	COG0205	6-phosphofructokinase activity
LS838_RS07885	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
LS838_RS07905	COG0058	SHG alpha-glucan phosphorylase activity
LS838_RS07910	COG0297	glycogen (starch) synthase activity
LS838_RS07915	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
LS838_RS07920	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
LS838_RS07925	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
LS838_RS07955	COG2223	nitrite transmembrane transporter activity
LS838_RS07975	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
LS838_RS07985	COG1113	amino acid transport
LS838_RS08000	COG3716	PTS system mannose fructose sorbose family IID component
LS838_RS08005	COG3715	PTS system
LS838_RS08020	COG1757	Na H antiporter
LS838_RS08045	COG1263	PTS System
LS838_RS08045	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LS838_RS08045	COG2190	(PTS) system
LS838_RS08055	COG1737	Transcriptional regulator
LS838_RS08060	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LS838_RS08060	COG1263	PTS System
LS838_RS08075	COG0557	exoribonuclease II activity
LS838_RS08085	COG1368	sulfuric ester hydrolase activity
LS838_RS08095	COG0438	transferase activity, transferring glycosyl groups
LS838_RS08100	COG0438	transferase activity, transferring glycosyl groups
LS838_RS08240	COG2235	arginine
LS838_RS08250	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
LS838_RS08315	COG0398	Pfam SNARE associated Golgi protein
LS838_RS08335	COG0505	Belongs to the CarA family
LS838_RS08340	COG1012	belongs to the aldehyde dehydrogenase family
LS838_RS08350	COG1033	growth of symbiont in host cell
LS838_RS08350	COG2409	Drug exporters of the RND superfamily
LS838_RS08350	COG2409	Drug exporters of the RND superfamily
LS838_RS08350	COG1033	growth of symbiont in host cell
LS838_RS08420	COG1132	(ABC) transporter
LS838_RS08430	COG2267	carboxylic ester hydrolase activity
LS838_RS08440	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
LS838_RS08445	COG1072	(Pantothenic acid kinase))
LS838_RS08465	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LS838_RS08470	COG1126	abc transporter atp-binding protein
LS838_RS08475	COG0765	amino acid transport
LS838_RS08480	COG3973	AAA domain
LS838_RS08500	COG0584	glycerophosphoryl diester phosphodiesterase
LS838_RS08525	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
LS838_RS08535	COG2246	polysaccharide biosynthetic process
LS838_RS08585	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
LS838_RS08590	COG3475	LICD family
LS838_RS08600	COG0438	transferase activity, transferring glycosyl groups
LS838_RS08605	COG0438	transferase activity, transferring glycosyl groups
LS838_RS08610	COG1216	Glycosyl transferase, family 2
LS838_RS08615	COG0562	UDP-galactopyranose mutase
LS838_RS08630	COG1316	TRANSCRIPTIONal
LS838_RS08655	COG1396	sequence-specific DNA binding
LS838_RS08660	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
LS838_RS08670	COG3706	GGDEF domain
LS838_RS08700	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LS838_RS08700	COG2190	(PTS) system
LS838_RS08700	COG1263	PTS System
LS838_RS08705	COG2188	Transcriptional regulator
LS838_RS08710	COG0366	Alpha amylase catalytic
LS838_RS08730	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
LS838_RS08740	COG1091	dTDP-4-dehydrorhamnose reductase activity
LS838_RS08745	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
LS838_RS08755	COG1088	dTDP-glucose 4,6-dehydratase activity
LS838_RS08760	COG2226	methyltransferase
LS838_RS08770	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
LS838_RS08775	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
LS838_RS08780	COG1461	Dihydroxyacetone kinase
LS838_RS08785	COG2376	Dihydroxyacetone kinase
LS838_RS08810	COG3976	FMN-binding domain protein
LS838_RS08810	COG1053	succinate dehydrogenase
LS838_RS08850	COG0562	UDP-galactopyranose mutase
LS838_RS08905	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
LS838_RS08910	COG4464	protein tyrosine phosphatase activity
LS838_RS08915	COG0489	protein tyrosine kinase activity
LS838_RS08925	COG1316	TRANSCRIPTIONal
LS838_RS08930	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
LS838_RS08945	COG1388	LysM domain
LS838_RS08945	COG0791	NLP P60 protein
LS838_RS08950	COG1388	LysM domain
LS838_RS08950	COG0791	NLP P60 protein
LS838_RS08955	COG0791	NLP P60 protein
LS838_RS08955	COG1388	LysM domain
LS838_RS08960	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LS838_RS08970	COG0194	GDP metabolic process
LS838_RS09015	COG0488	(ABC) transporter
LS838_RS09025	COG1316	TRANSCRIPTIONal
LS838_RS09040	COG1304	FMN binding
LS838_RS09045	COG1620	l-lactate permease
LS838_RS09050	COG1108	ABC-type Mn2 Zn2 transport systems permease components
LS838_RS09055	COG1121	(ABC) transporter
LS838_RS09060	COG0561	phosphatase activity
LS838_RS09065	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LS838_RS09065	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
LS838_RS09065	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LS838_RS09070	COG1105	Belongs to the carbohydrate kinase PfkB family
LS838_RS09075	COG1349	DNA-binding transcription factor activity
LS838_RS09085	COG1794	racemase activity, acting on amino acids and derivatives
LS838_RS09105	COG1132	(ABC) transporter
LS838_RS09110	COG1132	(ABC) transporter
LS838_RS09120	COG0012	GTP binding
LS838_RS09125	COG4481	Protein conserved in bacteria
LS838_RS09130	COG1475	DNA binding
LS838_RS09135	COG1192	Involved in chromosome partitioning
LS838_RS09165	COG0431	NADPH-dependent FMN reductase
LS838_RS09170	COG0431	NADPH-dependent FMN reductase
LS838_RS09185	COG1263	PTS System
LS838_RS09185	COG2190	(PTS) system
LS838_RS09185	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LS838_RS09195	COG3576	pyridoxamine 5-phosphate
LS838_RS09215	COG1136	(ABC) transporter
LS838_RS09220	COG0577	efflux transmembrane transporter activity
LS838_RS09230	COG0277	FAD linked oxidase domain protein
LS838_RS09235	COG3022	response to hydroperoxide
LS838_RS09260	COG0778	Nitroreductase
LS838_RS09285	COG0471	metal ion transport
LS838_RS09290	COG0114	fumarate hydratase activity
LS838_RS09320	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
LS838_RS09325	COG2365	Tyrosine phosphatase family
LS838_RS09335	COG0515	serine threonine protein kinase
LS838_RS09365	COG3442	glutamine amidotransferase
LS838_RS09385	COG1114	Component of the transport system for branched-chain amino acids
LS838_RS09400	COG0697	spore germination
LS838_RS09405	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
LS838_RS09410	COG0561	phosphatase activity
LS838_RS09460	COG2261	transglycosylase associated protein
LS838_RS09470	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
LS838_RS09475	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
LS838_RS09475	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
LS838_RS09485	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
LS838_RS09485	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
LS838_RS09545	COG1309	transcriptional regulator
LS838_RS09550	COG0577	efflux transmembrane transporter activity
LS838_RS09550	COG1136	(ABC) transporter
LS838_RS09565	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
LS838_RS09575	COG1696	Membrane protein involved in D-alanine export
LS838_RS09580	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LS838_RS09610	COG2217	Heavy metal translocating P-type atpase
LS838_RS09620	COG0675	Transposase, IS605 OrfB family
LS838_RS09645	COG1744	ABC transporter substrate-binding protein PnrA-like
LS838_RS09665	COG3279	Response regulator of the LytR AlgR family
LS838_RS09690	COG1744	ABC transporter substrate-binding protein PnrA-like
LS838_RS09715	COG1744	ABC transporter substrate-binding protein PnrA-like
LS838_RS09720	COG3845	ABC transporter
LS838_RS09725	COG4603	Belongs to the binding-protein-dependent transport system permease family
LS838_RS09730	COG1079	Belongs to the binding-protein-dependent transport system permease family
LS838_RS09745	COG0656	L-ascorbic acid biosynthetic process
LS838_RS09765	COG2801	Transposase and inactivated derivatives
LS838_RS09775	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LS838_RS09800	COG0582	viral genome integration into host DNA
LS838_RS09805	COG0783	Belongs to the Dps family
LS838_RS09815	COG2801	Transposase and inactivated derivatives
LS838_RS09825	COG1136	(ABC) transporter
LS838_RS09825	COG0577	efflux transmembrane transporter activity
LS838_RS09835	COG1428	Deoxynucleoside kinase
LS838_RS09840	COG1428	Deoxynucleoside kinase
LS838_RS09845	COG0765	amino acid transport
LS838_RS09850	COG1126	abc transporter atp-binding protein
LS838_RS09855	COG2252	PERMEase
LS838_RS09860	COG1136	(ABC) transporter
LS838_RS09870	COG1132	(ABC) transporter
LS838_RS09905	COG1131	(ABC) transporter
LS838_RS09920	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
LS838_RS09925	COG0028	Belongs to the TPP enzyme family
LS838_RS09930	COG0445	tRNA wobble uridine modification
LS838_RS09940	COG0706	membrane insertase activity