locus-tag	class	description
AO203_RS00040	COG3708	Transcriptional regulator
AO203_RS00040	COG2207	Transcriptional regulator
AO203_RS00045	COG3708	Transcriptional regulator
AO203_RS00045	COG2207	Transcriptional regulator
AO203_RS00060	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
AO203_RS00065	COG2801	Transposase and inactivated derivatives
AO203_RS00075	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
AO203_RS00080	COG2267	carboxylic ester hydrolase activity
AO203_RS00135	COG1132	(ABC) transporter
AO203_RS00140	COG3842	ATPase activity
AO203_RS00160	COG0488	(ABC) transporter
AO203_RS00170	COG0488	(ABC) transporter
AO203_RS00230	COG0531	amino acid
AO203_RS00250	COG0018	arginyl-trna synthetase
AO203_RS00265	COG3479	Phenolic acid decarboxylase
AO203_RS00275	COG1376	ErfK ybiS ycfS ynhG family protein
AO203_RS00280	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
AO203_RS00285	COG1686	Belongs to the peptidase S11 family
AO203_RS00300	COG1983	PspC domain protein
AO203_RS00335	COG0492	ferredoxin-NADP+ reductase activity
AO203_RS00345	COG3118	belongs to the thioredoxin family
AO203_RS00380	COG2244	polysaccharide biosynthetic process
AO203_RS00385	COG0495	leucyl-tRNA aminoacylation
AO203_RS00390	COG0671	phosphoesterase, PA-phosphatase related
AO203_RS00405	COG2814	Major facilitator Superfamily
AO203_RS00410	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
AO203_RS00465	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
AO203_RS00470	COG0557	exoribonuclease II activity
AO203_RS00475	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
AO203_RS00480	COG1368	sulfuric ester hydrolase activity
AO203_RS00490	COG0438	transferase activity, transferring glycosyl groups
AO203_RS00495	COG0438	transferase activity, transferring glycosyl groups
AO203_RS00670	COG0492	ferredoxin-NADP+ reductase activity
AO203_RS00675	COG0586	Pfam SNARE associated Golgi protein
AO203_RS00685	COG0647	UMP catabolic process
AO203_RS00695	COG0737	Belongs to the 5'-nucleotidase family
AO203_RS00705	COG0584	glycerophosphoryl diester phosphodiesterase
AO203_RS00715	COG0006	proline dipeptidase activity
AO203_RS00730	COG0668	transmembrane transport
AO203_RS00735	COG1131	(ABC) transporter
AO203_RS00745	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
AO203_RS00750	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
AO203_RS00760	COG1970	mechanosensitive ion channel activity
AO203_RS00765	COG3118	belongs to the thioredoxin family
AO203_RS00775	COG1193	negative regulation of DNA recombination
AO203_RS00780	COG3906	Belongs to the UPF0473 family
AO203_RS00785	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
AO203_RS00790	COG4472	Bacterial protein of unknown function (DUF965)
AO203_RS00795	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
AO203_RS00810	COG0513	Belongs to the DEAD box helicase family
AO203_RS00815	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
AO203_RS00820	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AO203_RS00825	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
AO203_RS00835	COG2255	four-way junction helicase activity
AO203_RS00840	COG0632	four-way junction helicase activity
AO203_RS00845	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
AO203_RS00850	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
AO203_RS00855	COG0459	protein refolding
AO203_RS00860	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
AO203_RS00865	COG0582	viral genome integration into host DNA
AO203_RS00975	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
AO203_RS00980	COG0488	(ABC) transporter
AO203_RS01005	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
AO203_RS01020	COG1214	PFAM Peptidase M22, glycoprotease
AO203_RS01025	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
AO203_RS01045	COG0470	DNA polymerase III
AO203_RS01050	COG3870	Protein conserved in bacteria
AO203_RS01055	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
AO203_RS01065	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
AO203_RS01070	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
AO203_RS01075	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
AO203_RS01085	COG0590	tRNA wobble adenosine to inosine editing
AO203_RS01090	COG2813	Specifically methylates the guanine in position
AO203_RS01100	COG0222	ribosome binding
AO203_RS01105	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
AO203_RS01130	COG0704	Plays a role in the regulation of phosphate uptake
AO203_RS01135	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
AO203_RS01140	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
AO203_RS01145	COG0581	inorganic phosphate transmembrane transporter activity
AO203_RS01150	COG0573	inorganic phosphate transmembrane transporter activity
AO203_RS01160	COG0081	regulation of translation
AO203_RS01165	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
AO203_RS01170	COG0250	Participates in transcription elongation, termination and antitermination
AO203_RS01185	COG1070	Carbohydrate kinase
AO203_RS01200	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AO203_RS01205	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
AO203_RS01210	COG0215	cysteine-tRNA ligase activity
AO203_RS01215	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AO203_RS01220	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
AO203_RS01225	COG0756	dUTP diphosphatase activity
AO203_RS01245	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
AO203_RS01255	COG0588	phosphoglycerate mutase activity
AO203_RS01265	COG1230	cation diffusion facilitator family transporter
AO203_RS01285	COG1011	Hydrolase
AO203_RS01310	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
AO203_RS01315	COG0101	tRNA pseudouridine synthase activity
AO203_RS01320	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
AO203_RS01325	COG1122	ATPase activity
AO203_RS01330	COG1122	ATPase activity
AO203_RS01335	COG0203	ribosomal protein L17
AO203_RS01340	COG0202	RNA polymerase activity
AO203_RS01345	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
AO203_RS01350	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
AO203_RS01360	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
AO203_RS01365	COG0563	adenylate kinase activity
AO203_RS01375	COG0200	Binds to the 23S rRNA
AO203_RS01380	COG1841	ribosomal large subunit assembly
AO203_RS01385	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
AO203_RS01390	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
AO203_RS01395	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
AO203_RS01400	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
AO203_RS01410	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
AO203_RS01415	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
AO203_RS01420	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
AO203_RS01425	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
AO203_RS01430	COG0255	Belongs to the universal ribosomal protein uL29 family
AO203_RS01435	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
AO203_RS01440	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
AO203_RS01445	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
AO203_RS01450	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
AO203_RS01455	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
AO203_RS01460	COG0089	rRNA binding
AO203_RS01465	COG0088	Forms part of the polypeptide exit tunnel
AO203_RS01470	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
AO203_RS01475	COG0051	transcription antitermination factor activity, RNA binding
AO203_RS01480	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
AO203_RS01485	COG0049	tRNA binding
AO203_RS01490	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
AO203_RS01510	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
AO203_RS01515	COG0085	RNA polymerase activity
AO203_RS01520	COG0542	response to heat
AO203_RS01525	COG1956	GAF domain-containing protein
AO203_RS01545	COG2801	Transposase and inactivated derivatives
AO203_RS01555	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
AO203_RS01560	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AO203_RS01565	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
AO203_RS01575	COG0037	tRNA processing
AO203_RS01590	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
AO203_RS01600	COG0193	aminoacyl-tRNA hydrolase activity
AO203_RS01605	COG0039	L-malate dehydrogenase activity
AO203_RS01630	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AO203_RS01635	COG0736	holo-[acyl-carrier-protein] synthase activity
AO203_RS01645	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
AO203_RS01650	COG0254	rRNA binding
AO203_RS01720	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
AO203_RS01725	COG0519	Catalyzes the synthesis of GMP from XMP
AO203_RS01740	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
AO203_RS01750	COG2233	PERMEase
AO203_RS01760	COG4690	dipeptidase activity
AO203_RS01780	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
AO203_RS01785	COG0504	CTP synthase activity
AO203_RS01790	COG3343	RNA polymerase activity
AO203_RS01800	COG1078	dGTPase activity
AO203_RS01825	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
AO203_RS01850	COG2801	Transposase and inactivated derivatives
AO203_RS01865	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
AO203_RS01870	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
AO203_RS01875	COG4466	Protein conserved in bacteria
AO203_RS01880	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
AO203_RS01890	COG0084	hydrolase, TatD family'
AO203_RS01895	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AO203_RS01895	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AO203_RS01900	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
AO203_RS01910	COG2131	deaminase
AO203_RS01935	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AO203_RS01945	COG3579	cysteine-type endopeptidase activity
AO203_RS01950	COG3344	reverse transcriptase
AO203_RS01965	COG0516	GMP reductase activity
AO203_RS01965	COG0517	IMP dehydrogenase activity
AO203_RS01970	COG1418	mRNA catabolic process
AO203_RS01975	COG3579	cysteine-type endopeptidase activity
AO203_RS01990	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
AO203_RS02000	COG1368	sulfuric ester hydrolase activity
AO203_RS02005	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
AO203_RS02010	COG1316	TRANSCRIPTIONal
AO203_RS02020	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
AO203_RS02030	COG0588	phosphoglycerate mutase activity
AO203_RS02040	COG0673	inositol 2-dehydrogenase activity
AO203_RS02050	COG0475	glutathione-regulated potassium exporter activity
AO203_RS02050	COG0569	domain protein
AO203_RS02060	COG1705	Flagellar rod assembly protein muramidase FlgJ
AO203_RS02090	COG3158	transport of potassium into the cell
AO203_RS02095	COG3590	peptidase
AO203_RS02100	COG2814	Major facilitator Superfamily
AO203_RS02110	COG2151	metal-sulfur cluster biosynthetic enzyme
AO203_RS02115	COG0602	queuosine metabolic process
AO203_RS02135	COG0367	asparagine synthase
AO203_RS02150	COG0519	Catalyzes the synthesis of GMP from XMP
AO203_RS02155	COG3639	organic phosphonate transmembrane transporter activity
AO203_RS02160	COG3639	organic phosphonate transmembrane transporter activity
AO203_RS02165	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
AO203_RS02175	COG0589	response to stress
AO203_RS02180	COG2365	Tyrosine phosphatase family
AO203_RS02190	COG1028	Short-chain dehydrogenase reductase Sdr
AO203_RS02195	COG2261	transglycosylase associated protein
AO203_RS02230	COG2801	Transposase and inactivated derivatives
AO203_RS02280	COG1181	Belongs to the D-alanine--D-alanine ligase family
AO203_RS02290	COG1126	abc transporter atp-binding protein
AO203_RS02295	COG0765	amino acid transport
AO203_RS02310	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
AO203_RS02330	COG1216	Glycosyl transferase, family 2
AO203_RS02340	COG2801	Transposase and inactivated derivatives
AO203_RS02345	COG0328	RNA-DNA hybrid ribonuclease activity
AO203_RS02355	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AO203_RS02365	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
AO203_RS02375	COG0861	Integral membrane protein TerC family
AO203_RS02380	COG3189	MarR family transcriptional regulator
AO203_RS02385	COG2094	Belongs to the DNA glycosylase MPG family
AO203_RS02390	COG0765	amino acid transport
AO203_RS02395	COG1126	abc transporter atp-binding protein
AO203_RS02420	COG1215	transferase activity, transferring glycosyl groups
AO203_RS02530	COG1136	(ABC) transporter
AO203_RS02560	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
AO203_RS02565	COG1704	LemA family
AO203_RS02570	COG0501	Belongs to the peptidase M48B family
AO203_RS02600	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
AO203_RS02605	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AO203_RS02610	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
AO203_RS02625	COG5002	protein histidine kinase activity
AO203_RS02630	COG0745	RESPONSE REGULATOR receiver
AO203_RS02750	COG0242	peptide deformylase activity
AO203_RS02770	COG0708	Exodeoxyribonuclease III
AO203_RS02775	COG3001	Fructosamine kinase
AO203_RS02780	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AO203_RS02785	COG0656	L-ascorbic acid biosynthetic process
AO203_RS02795	COG1011	Hydrolase
AO203_RS02810	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AO203_RS02840	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AO203_RS02845	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
AO203_RS02865	COG0628	permease
AO203_RS02870	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AO203_RS02885	COG2096	Adenosyltransferase
AO203_RS02910	COG2801	Transposase and inactivated derivatives
AO203_RS02960	COG0390	transport system, permease component
AO203_RS02965	COG4619	ABC transporter
AO203_RS02975	COG1122	ATPase activity
AO203_RS02985	COG2814	Major facilitator Superfamily
AO203_RS03060	COG2801	Transposase and inactivated derivatives
AO203_RS03070	COG1285	pathogenesis
AO203_RS03080	COG2261	transglycosylase associated protein
AO203_RS03110	COG1307	EDD domain protein, DegV family
AO203_RS03120	COG0305	Participates in initiation and elongation during chromosome replication
AO203_RS03125	COG0359	binds to the 23S rRNA
AO203_RS03140	COG1132	(ABC) transporter
AO203_RS03150	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
AO203_RS03155	COG0629	single-stranded DNA binding
AO203_RS03160	COG0360	Binds together with S18 to 16S ribosomal RNA
AO203_RS03165	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
AO203_RS03170	COG0187	DNA topoisomerase II activity
AO203_RS03175	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
AO203_RS03180	COG2501	S4 domain
AO203_RS03185	COG0592	DNA-directed DNA polymerase activity
AO203_RS03190	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
AO203_RS03195	COG0230	Belongs to the bacterial ribosomal protein bL34 family
AO203_RS03200	COG0594	ribonuclease P activity
AO203_RS03205	COG0706	membrane insertase activity
AO203_RS03210	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
AO203_RS03215	COG0445	tRNA wobble uridine modification
AO203_RS03225	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
AO203_RS03250	COG2217	Heavy metal translocating P-type atpase
AO203_RS03310	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AO203_RS03330	COG2801	Transposase and inactivated derivatives
AO203_RS03350	COG4975	Glucose uptake
AO203_RS03360	COG0004	ammonium transporteR
AO203_RS03370	COG0157	Belongs to the NadC ModD family
AO203_RS03375	COG0477	Major facilitator Superfamily
AO203_RS03385	COG2252	PERMEase
AO203_RS03395	COG1373	ATPase (AAA superfamily
AO203_RS03400	COG2801	Transposase and inactivated derivatives
AO203_RS03410	COG0561	phosphatase activity
AO203_RS03415	COG1428	Deoxynucleoside kinase
AO203_RS03420	COG1428	Deoxynucleoside kinase
AO203_RS03425	COG0363	glucosamine-6-phosphate deaminase activity
AO203_RS03430	COG0656	L-ascorbic acid biosynthetic process
AO203_RS03475	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
AO203_RS03480	COG4115	mRNA cleavage
AO203_RS03485	COG2161	toxin-antitoxin pair type II binding
AO203_RS03500	COG2217	Heavy metal translocating P-type atpase
AO203_RS03505	COG0517	IMP dehydrogenase activity
AO203_RS03505	COG0516	GMP reductase activity
AO203_RS03520	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AO203_RS03525	COG1696	Membrane protein involved in D-alanine export
AO203_RS03530	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AO203_RS03535	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
AO203_RS03540	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
AO203_RS03580	COG2244	polysaccharide biosynthetic process
AO203_RS03610	COG0542	response to heat
AO203_RS03615	COG0681	Belongs to the peptidase S26 family
AO203_RS03650	COG1131	(ABC) transporter
AO203_RS03685	COG2502	aspartate--ammonia ligase
AO203_RS03705	COG0516	GMP reductase activity
AO203_RS03710	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
AO203_RS03715	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
AO203_RS03750	COG2801	Transposase and inactivated derivatives
AO203_RS03755	COG3442	glutamine amidotransferase
AO203_RS03760	COG0351	phosphomethylpyrimidine kinase
AO203_RS03765	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
AO203_RS03775	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
AO203_RS03780	COG2365	Tyrosine phosphatase family
AO203_RS03820	COG0488	(ABC) transporter
AO203_RS03830	COG1132	(ABC) transporter
AO203_RS03870	COG0308	aminopeptidase N
AO203_RS03875	COG3104	oligopeptide transport
AO203_RS03890	COG3022	response to hydroperoxide
AO203_RS03900	COG0406	alpha-ribazole phosphatase activity
AO203_RS03910	COG0577	efflux transmembrane transporter activity
AO203_RS03915	COG1136	(ABC) transporter
AO203_RS03935	COG0431	NADPH-dependent FMN reductase
AO203_RS03940	COG0431	NADPH-dependent FMN reductase
AO203_RS03960	COG0357	Ribosomal RNA small subunit methyltransferase G
AO203_RS03970	COG1192	Involved in chromosome partitioning
AO203_RS03975	COG1475	DNA binding
AO203_RS03980	COG4481	Protein conserved in bacteria
AO203_RS03985	COG0012	GTP binding
AO203_RS03995	COG1132	(ABC) transporter
AO203_RS04000	COG1132	(ABC) transporter
AO203_RS04015	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AO203_RS04035	COG3655	Transcriptional regulator
AO203_RS04055	COG1349	DNA-binding transcription factor activity
AO203_RS04060	COG1105	Belongs to the carbohydrate kinase PfkB family
AO203_RS04065	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AO203_RS04065	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AO203_RS04065	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AO203_RS04070	COG0640	Transcriptional regulator
AO203_RS04080	COG1121	(ABC) transporter
AO203_RS04085	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AO203_RS04105	COG1164	Oligoendopeptidase f
AO203_RS04110	COG1316	TRANSCRIPTIONal
AO203_RS04115	COG1811	Na channel or pump
AO203_RS04130	COG0488	(ABC) transporter
AO203_RS04190	COG0791	NLP P60 protein
AO203_RS04210	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
AO203_RS04215	COG1316	TRANSCRIPTIONal
AO203_RS04225	COG0489	protein tyrosine kinase activity
AO203_RS04230	COG4464	protein tyrosine phosphatase activity
AO203_RS04235	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
AO203_RS04240	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
AO203_RS04255	COG0438	transferase activity, transferring glycosyl groups
AO203_RS04260	COG1216	Glycosyl transferase, family 2
AO203_RS04300	COG1192	Involved in chromosome partitioning
AO203_RS04325	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
AO203_RS04330	COG1091	dTDP-4-dehydrorhamnose reductase activity
AO203_RS04335	COG1210	Utp--glucose-1-phosphate uridylyltransferase
AO203_RS04380	COG0252	asparaginase activity
AO203_RS04400	COG1136	(ABC) transporter
AO203_RS04420	COG0588	phosphoglycerate mutase activity
AO203_RS04430	COG3973	AAA domain
AO203_RS04450	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
AO203_RS04460	COG1846	Transcriptional regulator
AO203_RS04480	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
AO203_RS04485	COG2267	carboxylic ester hydrolase activity
AO203_RS04500	COG1132	(ABC) transporter
AO203_RS04580	COG1104	cysteine desulfurase activity
AO203_RS04585	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
AO203_RS04590	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
AO203_RS04600	COG1045	serine acetyltransferase
AO203_RS04605	COG0626	cystathionine gamma-synthase activity
AO203_RS04610	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AO203_RS04650	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AO203_RS04660	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AO203_RS04665	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AO203_RS04670	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
AO203_RS04675	COG1028	Short-chain dehydrogenase reductase Sdr
AO203_RS04680	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AO203_RS04685	COG0511	ligase activity, forming carbon-carbon bonds
AO203_RS04690	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AO203_RS04695	COG0439	Biotin carboxylase
AO203_RS04700	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
AO203_RS04705	COG0825	malonyl-CoA metabolic process
AO203_RS04710	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
AO203_RS04720	COG1268	BioY protein
AO203_RS04740	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
AO203_RS04765	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
AO203_RS04805	COG2223	nitrite transmembrane transporter activity
AO203_RS04810	COG2801	Transposase and inactivated derivatives
AO203_RS04855	COG2176	DNA-directed DNA polymerase activity
AO203_RS04875	COG1175	transmembrane transport
AO203_RS04910	COG1033	growth of symbiont in host cell
AO203_RS04910	COG2409	Drug exporters of the RND superfamily
AO203_RS04925	COG1012	belongs to the aldehyde dehydrogenase family
AO203_RS04945	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AO203_RS04950	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
AO203_RS04985	COG2801	Transposase and inactivated derivatives
AO203_RS04990	COG1621	beta-fructofuranosidase activity
AO203_RS05015	COG3715	PTS system
AO203_RS05020	COG3716	PTS system mannose fructose sorbose family IID component
AO203_RS05030	COG0583	DNA-binding transcription factor activity
AO203_RS05040	COG0110	maltose O-acetyltransferase activity
AO203_RS05045	COG2801	Transposase and inactivated derivatives
AO203_RS05050	COG1113	amino acid transport
AO203_RS05055	COG1012	belongs to the aldehyde dehydrogenase family
AO203_RS05055	COG1454	alcohol dehydrogenase
AO203_RS05060	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
AO203_RS05080	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
AO203_RS05110	COG1205	dead DEAH box helicase
AO203_RS05110	COG1111	helicase
AO203_RS05140	COG2188	Transcriptional regulator
AO203_RS05145	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
AO203_RS05190	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AO203_RS05195	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AO203_RS05220	COG0588	phosphoglycerate mutase activity
AO203_RS05250	COG0366	Alpha amylase catalytic
AO203_RS05275	COG2801	Transposase and inactivated derivatives
AO203_RS05310	COG2188	Transcriptional regulator
AO203_RS05320	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
AO203_RS05345	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
AO203_RS05375	COG3091	SprT-like family
AO203_RS05385	COG1705	Flagellar rod assembly protein muramidase FlgJ
AO203_RS05395	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
AO203_RS05400	COG4851	CamS sex pheromone cAM373 precursor
AO203_RS05405	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AO203_RS05410	COG0154	amidase activity
AO203_RS05415	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AO203_RS05420	COG1597	lipid kinase activity
AO203_RS05435	COG0670	Belongs to the BI1 family
AO203_RS05455	COG1757	Na H antiporter
AO203_RS05460	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AO203_RS05480	COG1278	Cold shock
AO203_RS05520	COG4716	Myosin-crossreactive antigen
AO203_RS05530	COG0456	acetyltransferase
AO203_RS05540	COG2801	Transposase and inactivated derivatives
AO203_RS05570	COG0477	Major facilitator Superfamily
AO203_RS05600	COG0488	(ABC) transporter
AO203_RS05620	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AO203_RS05625	COG0765	amino acid transport
AO203_RS05630	COG0765	amino acid transport
AO203_RS05670	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
AO203_RS05690	COG3158	transport of potassium into the cell
AO203_RS05700	COG2188	Transcriptional regulator
AO203_RS05715	COG0561	phosphatase activity
AO203_RS05735	COG0396	ATPase activity
AO203_RS05740	COG0719	Fe-S assembly protein
AO203_RS05745	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AO203_RS05750	COG0822	iron-sulfur transferase activity
AO203_RS05755	COG0719	Fe-S assembly protein
AO203_RS05760	COG2151	metal-sulfur cluster biosynthetic enzyme
AO203_RS05775	COG1349	DNA-binding transcription factor activity
AO203_RS05780	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
AO203_RS05840	COG1263	PTS System
AO203_RS05840	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AO203_RS05840	COG2190	(PTS) system
AO203_RS05855	COG1253	flavin adenine dinucleotide binding
AO203_RS05870	COG0513	Belongs to the DEAD box helicase family
AO203_RS05875	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AO203_RS05890	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
AO203_RS05900	COG0716	FMN binding
AO203_RS05905	COG0024	Methionine aminopeptidase
AO203_RS05910	COG1295	ribonuclease BN
AO203_RS05915	COG1210	Utp--glucose-1-phosphate uridylyltransferase
AO203_RS05925	COG0183	Belongs to the thiolase family
AO203_RS05935	COG3425	synthase
AO203_RS05955	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AO203_RS05975	COG1253	flavin adenine dinucleotide binding
AO203_RS05980	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
AO203_RS05995	COG0542	response to heat
AO203_RS06005	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AO203_RS06015	COG1393	Belongs to the ArsC family
AO203_RS06020	COG4862	establishment of competence for transformation
AO203_RS06040	COG2357	RelA SpoT domain protein
AO203_RS06045	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
AO203_RS06050	COG0564	pseudouridine synthase activity
AO203_RS06075	COG2706	6-phosphogluconolactonase activity
AO203_RS06080	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
AO203_RS06090	COG0628	permease
AO203_RS06105	COG1674	ftsk spoiiie
AO203_RS06115	COG0612	Peptidase, M16
AO203_RS06120	COG1028	Short-chain dehydrogenase reductase Sdr
AO203_RS06125	COG1426	Protein conserved in bacteria
AO203_RS06130	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
AO203_RS06135	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
AO203_RS06140	COG1418	mRNA catabolic process
AO203_RS06150	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AO203_RS06155	COG1739	Uncharacterized protein family UPF0029
AO203_RS06160	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
AO203_RS06175	COG0653	protein targeting
AO203_RS06180	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
AO203_RS06190	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
AO203_RS06195	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
AO203_RS06200	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
AO203_RS06215	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AO203_RS06220	COG0556	nucleotide-excision repair
AO203_RS06225	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
AO203_RS06235	COG2801	Transposase and inactivated derivatives
AO203_RS06240	COG1660	Displays ATPase and GTPase activities
AO203_RS06245	COG0391	Required for morphogenesis under gluconeogenic growth conditions
AO203_RS06250	COG1481	regulation of sporulation
AO203_RS06255	COG0740	serine-type endopeptidase activity
AO203_RS06315	COG2390	Transcriptional regulator
AO203_RS06325	COG0126	phosphoglycerate kinase activity
AO203_RS06330	COG0149	triose-phosphate isomerase activity
AO203_RS06345	COG3344	reverse transcriptase
AO203_RS06355	COG0561	phosphatase activity
AO203_RS06360	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
AO203_RS06365	COG0280	phosphate acetyltransferase
AO203_RS06370	COG0802	atpase or kinase
AO203_RS06380	COG0812	UDP-N-acetylmuramate dehydrogenase activity
AO203_RS06385	COG3842	ATPase activity
AO203_RS06395	COG4208	sulfate ABC transporter
AO203_RS06410	COG4856	YbbR-like protein
AO203_RS06415	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AO203_RS06425	COG0561	phosphatase activity
AO203_RS06435	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AO203_RS06440	COG1929	Belongs to the glycerate kinase type-1 family
AO203_RS06470	COG0217	transcriptional regulatory protein
AO203_RS06480	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AO203_RS06510	COG0827	DNA restriction-modification system
AO203_RS06515	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
AO203_RS06530	COG1482	cell wall glycoprotein biosynthetic process
AO203_RS06540	COG0745	RESPONSE REGULATOR receiver
AO203_RS06545	COG3850	Histidine kinase
AO203_RS06545	COG5002	protein histidine kinase activity
AO203_RS06550	COG1368	sulfuric ester hydrolase activity
AO203_RS06560	COG0166	Belongs to the GPI family
AO203_RS06580	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
AO203_RS06630	COG1396	sequence-specific DNA binding
AO203_RS06640	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
AO203_RS06645	COG1435	thymidine kinase activity
AO203_RS06650	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
AO203_RS06655	COG2890	protein-(glutamine-N5) methyltransferase activity
AO203_RS06660	COG0009	L-threonylcarbamoyladenylate synthase
AO203_RS06665	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
AO203_RS06670	COG0356	it plays a direct role in the translocation of protons across the membrane
AO203_RS06675	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
AO203_RS06680	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
AO203_RS06685	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
AO203_RS06690	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
AO203_RS06695	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
AO203_RS06700	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
AO203_RS06705	COG0355	proton-transporting ATP synthase activity, rotational mechanism
AO203_RS06725	COG0772	Belongs to the SEDS family
AO203_RS06730	COG0589	response to stress
AO203_RS06750	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
AO203_RS06760	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
AO203_RS06765	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
AO203_RS06770	COG1104	cysteine desulfurase activity
AO203_RS06775	COG0301	tRNA thio-modification
AO203_RS06960	COG0463	Glycosyl transferase, family 2
AO203_RS06975	COG0525	valine-tRNA ligase activity
AO203_RS06985	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AO203_RS06990	COG2003	Belongs to the UPF0758 family
AO203_RS06995	COG1077	Cell shape determining protein MreB Mrl
AO203_RS07000	COG1792	Involved in formation and maintenance of cell shape
AO203_RS07020	COG2001	Belongs to the MraZ family
AO203_RS07025	COG0275	rRNA processing
AO203_RS07035	COG0768	penicillin binding
AO203_RS07040	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AO203_RS07045	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
AO203_RS07050	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
AO203_RS07055	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
AO203_RS07065	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
AO203_RS07070	COG1799	cell septum assembly
AO203_RS07090	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
AO203_RS07095	COG1278	Cold shock
AO203_RS07100	COG0494	nUDIX hydrolase
AO203_RS07110	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
AO203_RS07115	COG1104	cysteine desulfurase activity
AO203_RS07125	COG0482	sulfurtransferase activity
AO203_RS07135	COG0406	alpha-ribazole phosphatase activity
AO203_RS07145	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
AO203_RS07165	COG5503	Protein of unknown function (DUF1447)
AO203_RS07170	COG0242	peptide deformylase activity
AO203_RS07175	COG1217	gtp-binding protein TYPA
AO203_RS07180	COG0772	Belongs to the SEDS family
AO203_RS07190	COG0742	ribosomal rna small subunit methyltransferase
AO203_RS07195	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
AO203_RS07200	COG3480	Lon protease (S16) C-terminal proteolytic domain
AO203_RS07205	COG1555	photosystem II stabilization
AO203_RS07210	COG2333	competence protein COMEC
AO203_RS07210	COG0658	competence protein
AO203_RS07215	COG1466	dna polymerase III delta subunit
AO203_RS07220	COG0268	Binds directly to 16S ribosomal RNA
AO203_RS07225	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
AO203_RS07240	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
AO203_RS07245	COG0544	peptidyl-prolyl cis-trans isomerase activity
AO203_RS07250	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
AO203_RS07255	COG0218	Necessary for normal cell division and for the maintenance of normal septation
AO203_RS07270	COG0527	aspartate kinase activity
AO203_RS07275	COG0019	diaminopimelate decarboxylase activity
AO203_RS07280	COG2171	N-acyltransferase activity
AO203_RS07285	COG1473	amidohydrolase
AO203_RS07290	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AO203_RS07295	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
AO203_RS07300	COG0436	Aminotransferase
AO203_RS07305	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
AO203_RS07310	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
AO203_RS07315	COG1051	belongs to the nudix hydrolase family
AO203_RS07345	COG4989	oxidoreductase activity
AO203_RS07360	COG0148	phosphopyruvate hydratase activity
AO203_RS07410	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
AO203_RS07415	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
AO203_RS07430	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
AO203_RS07440	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AO203_RS07445	COG2011	ABC-type metal ion transport system permease component
AO203_RS07450	COG1373	ATPase (AAA superfamily
AO203_RS07460	COG0114	fumarate hydratase activity
AO203_RS07495	COG0039	L-malate dehydrogenase activity
AO203_RS07520	COG3579	cysteine-type endopeptidase activity
AO203_RS07530	COG0471	metal ion transport
AO203_RS07535	COG2267	carboxylic ester hydrolase activity
AO203_RS07545	COG3052	prosthetic group binding
AO203_RS07585	COG2707	UPF0756 membrane protein
AO203_RS07600	COG4720	Psort location CytoplasmicMembrane, score
AO203_RS07625	COG1881	PFAM PEBP family protein
AO203_RS07635	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
AO203_RS07640	COG2264	protein methyltransferase activity
AO203_RS07650	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AO203_RS07655	COG1490	D-aminoacyl-tRNA deacylase activity
AO203_RS07660	COG0124	histidyl-tRNA synthetase
AO203_RS07665	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
AO203_RS07670	COG0436	Aminotransferase
AO203_RS07680	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
AO203_RS07690	COG0561	phosphatase activity
AO203_RS07700	COG0531	amino acid
AO203_RS07705	COG2801	Transposase and inactivated derivatives
AO203_RS07710	COG0586	Pfam SNARE associated Golgi protein
AO203_RS07715	COG0322	excinuclease ABC activity
AO203_RS07720	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
AO203_RS07725	COG2755	lipolytic protein G-D-S-L family
AO203_RS07725	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
AO203_RS07730	COG1234	tRNA 3'-trailer cleavage
AO203_RS07735	COG0300	oxidoreductase activity
AO203_RS07745	COG0333	Belongs to the bacterial ribosomal protein bL32 family
AO203_RS07750	COG0737	Belongs to the 5'-nucleotidase family
AO203_RS07760	COG0587	DNA-directed DNA polymerase activity
AO203_RS07765	COG0205	6-phosphofructokinase activity
AO203_RS07775	COG2996	Protein conserved in bacteria
AO203_RS07790	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
AO203_RS07795	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
AO203_RS07800	COG1187	pseudouridine synthase activity
AO203_RS07805	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
AO203_RS07820	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
AO203_RS07825	COG0539	negative regulation of cytoplasmic translation
AO203_RS07830	COG1160	GTP binding
AO203_RS07845	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AO203_RS07850	COG0617	tRNA 3'-terminal CCA addition
AO203_RS07855	COG1272	protein, Hemolysin III
AO203_RS07860	COG1307	EDD domain protein, DegV family
AO203_RS07865	COG4479	Belongs to the UPF0346 family
AO203_RS07870	COG0025	NhaP-type Na H and K H
AO203_RS07875	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
AO203_RS07880	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
AO203_RS07885	COG0758	DNA mediated transformation
AO203_RS07890	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AO203_RS07895	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
AO203_RS07910	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
AO203_RS07920	COG2801	Transposase and inactivated derivatives
AO203_RS07945	COG0825	malonyl-CoA metabolic process
AO203_RS07955	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
AO203_RS07955	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
AO203_RS07965	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
AO203_RS07970	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
AO203_RS08020	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
AO203_RS08025	COG0569	domain protein
AO203_RS08030	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AO203_RS08035	COG0514	ATP-dependent DNA helicase (RecQ)
AO203_RS08060	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
AO203_RS08085	COG3344	reverse transcriptase
AO203_RS08090	COG0534	Mate efflux family protein
AO203_RS08100	COG0534	Mate efflux family protein
AO203_RS08105	COG2195	Cleaves the N-terminal amino acid of tripeptides
AO203_RS08110	COG2184	nucleotidyltransferase activity
AO203_RS08115	COG2274	protein secretion by the type I secretion system
AO203_RS08120	COG1132	(ABC) transporter
AO203_RS08275	COG1335	isochorismatase
AO203_RS08280	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
AO203_RS08310	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
AO203_RS08325	COG1193	negative regulation of DNA recombination
AO203_RS08340	COG0488	(ABC) transporter
AO203_RS08355	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AO203_RS08390	COG2190	(PTS) system
AO203_RS08390	COG1263	PTS System
AO203_RS08390	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AO203_RS08395	COG2188	Transcriptional regulator
AO203_RS08400	COG0366	Alpha amylase catalytic
AO203_RS08415	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AO203_RS08485	COG0446	pyridine nucleotide-disulphide oxidoreductase
AO203_RS08530	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AO203_RS08595	COG3590	peptidase
AO203_RS08605	COG0531	amino acid
AO203_RS08610	COG1473	amidohydrolase
AO203_RS08625	COG0833	amino acid
AO203_RS08640	COG1288	antiporter activity
AO203_RS08675	COG1114	Component of the transport system for branched-chain amino acids
AO203_RS08680	COG1811	Na channel or pump
AO203_RS08720	COG2801	Transposase and inactivated derivatives
AO203_RS08745	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
AO203_RS08800	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
AO203_RS08800	COG0302	gtp cyclohydrolase
AO203_RS08805	COG0285	dihydrofolate synthase activity
AO203_RS08810	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
AO203_RS08815	COG1051	belongs to the nudix hydrolase family
AO203_RS08825	COG0789	Transcriptional regulator
AO203_RS08830	COG0765	amino acid transport
AO203_RS08835	COG0765	amino acid transport
AO203_RS08840	COG1126	abc transporter atp-binding protein
AO203_RS08890	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AO203_RS08925	COG3830	Belongs to the UPF0237 family
AO203_RS08965	COG0783	Belongs to the Dps family
AO203_RS08970	COG2801	Transposase and inactivated derivatives
AO203_RS08990	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
AO203_RS09000	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
AO203_RS09005	COG0187	DNA topoisomerase II activity
AO203_RS09015	COG0583	DNA-binding transcription factor activity
AO203_RS09020	COG1227	inorganic diphosphatase activity
AO203_RS09105	COG4974	Belongs to the 'phage' integrase family
AO203_RS09120	COG1307	EDD domain protein, DegV family
AO203_RS09135	COG2801	Transposase and inactivated derivatives
AO203_RS09145	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
AO203_RS09150	COG0505	Belongs to the CarA family
AO203_RS09155	COG0564	pseudouridine synthase activity
AO203_RS09165	COG2759	Belongs to the formate--tetrahydrofolate ligase family
AO203_RS09180	COG0116	Belongs to the methyltransferase superfamily
AO203_RS09190	COG3599	regulation of cell shape
AO203_RS09195	COG4474	Belongs to the UPF0398 family
AO203_RS09200	COG3331	DNA recombination
AO203_RS09205	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AO203_RS09220	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
AO203_RS09225	COG3935	DnaD domain protein
AO203_RS09230	COG0017	Asparaginyl-tRNA synthetase
AO203_RS09240	COG1199	ATP-dependent helicase activity
AO203_RS09240	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AO203_RS09245	COG1074	ATP-dependent DNA helicase activity
AO203_RS09250	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
AO203_RS09255	COG0083	homoserine kinase activity
AO203_RS09270	COG1304	FMN binding
AO203_RS09275	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
AO203_RS09275	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
AO203_RS09325	COG1131	(ABC) transporter
AO203_RS09330	COG1725	Transcriptional regulator
AO203_RS09335	COG2195	Cleaves the N-terminal amino acid of tripeptides
AO203_RS09340	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
AO203_RS09345	COG2384	SAM-dependent methyltransferase
AO203_RS09405	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AO203_RS09410	COG0358	DNA primase activity
AO203_RS09415	COG0751	glycine-tRNA ligase activity
AO203_RS09420	COG0752	glycyl-tRNA synthetase alpha subunit
AO203_RS09425	COG1381	Involved in DNA repair and RecF pathway recombination
AO203_RS09430	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
AO203_RS09435	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
AO203_RS09440	COG1702	phosphate starvation-inducible protein PhoH
AO203_RS09450	COG0828	Belongs to the bacterial ribosomal protein bS21 family
AO203_RS09460	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
AO203_RS09525	COG3299	homolog of phage Mu protein gp47
AO203_RS09680	COG1061	Type III restriction enzyme res subunit
AO203_RS09750	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AO203_RS09775	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
AO203_RS09780	COG1518	maintenance of DNA repeat elements
AO203_RS09825	COG0083	homoserine kinase activity
AO203_RS09830	COG0460	homoserine dehydrogenase
AO203_RS09840	COG0527	aspartate kinase activity
AO203_RS09910	COG2235	arginine
AO203_RS09915	COG0583	DNA-binding transcription factor activity
AO203_RS09920	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
AO203_RS09940	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AO203_RS09945	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
AO203_RS09950	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
AO203_RS09950	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
AO203_RS09955	COG3764	Sortase (surface protein transpeptidase)
AO203_RS09960	COG0481	GTPase activity
AO203_RS09985	COG0484	heat shock protein binding
AO203_RS09990	COG0443	Heat shock 70 kDa protein
AO203_RS09995	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
AO203_RS10000	COG1420	regulation of RNA biosynthetic process
AO203_RS10010	COG0196	riboflavin kinase activity
AO203_RS10015	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
AO203_RS10020	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
AO203_RS10025	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
AO203_RS10035	COG2740	Nucleic-acid-binding protein implicated in transcription termination
AO203_RS10040	COG0195	Participates in both transcription termination and antitermination
AO203_RS10045	COG0779	Required for maturation of 30S ribosomal subunits
AO203_RS10055	COG0442	prolyl-tRNA aminoacylation
AO203_RS10060	COG0750	zinc metalloprotease
AO203_RS10065	COG4589	Belongs to the CDS family
AO203_RS10070	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
AO203_RS10075	COG0233	cytoplasmic translational termination
AO203_RS10080	COG0528	UMP kinase activity
AO203_RS10085	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
AO203_RS10090	COG0052	Belongs to the universal ribosomal protein uS2 family
AO203_RS10095	COG2827	Endonuclease containing a URI domain
AO203_RS10100	COG0204	Acyl-transferase
AO203_RS10110	COG3590	peptidase
AO203_RS10115	COG1132	(ABC) transporter
AO203_RS10120	COG1132	(ABC) transporter
AO203_RS10125	COG3763	UPF0154 protein
AO203_RS10130	COG4224	UPF0291 protein
AO203_RS10135	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
AO203_RS10150	COG0335	large ribosomal subunit rRNA binding
AO203_RS10155	COG0336	Belongs to the RNA methyltransferase TrmD family
AO203_RS10160	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
AO203_RS10165	COG0228	four-way junction DNA binding
AO203_RS10170	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
AO203_RS10175	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
AO203_RS10180	COG0531	amino acid
AO203_RS10200	COG0552	protein localization to endoplasmic reticulum
AO203_RS10205	COG1196	nuclear chromosome segregation
AO203_RS10210	COG0571	ribonuclease III activity
AO203_RS10230	COG0601	transmembrane transport
AO203_RS10235	COG4608	Belongs to the ABC transporter superfamily
AO203_RS10245	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AO203_RS10250	COG0416	fatty acid biosynthetic process
AO203_RS10255	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
AO203_RS10270	COG0227	Belongs to the bacterial ribosomal protein bL28 family
AO203_RS10280	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
AO203_RS10285	COG1162	GTPase activity
AO203_RS10290	COG0515	serine threonine protein kinase
AO203_RS10290	COG2815	serine threonine protein kinase
AO203_RS10300	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AO203_RS10300	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
AO203_RS10305	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
AO203_RS10310	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
AO203_RS10315	COG1758	RNA polymerase activity
AO203_RS10320	COG0194	GDP metabolic process
AO203_RS10330	COG2801	Transposase and inactivated derivatives
AO203_RS10345	COG0497	DNA recombination
AO203_RS10350	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
AO203_RS10360	COG1722	exodeoxyribonuclease VII activity
AO203_RS10365	COG1570	exodeoxyribonuclease VII activity
AO203_RS10370	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
AO203_RS10380	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
AO203_RS10390	COG1302	Protein conserved in bacteria
AO203_RS10395	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
AO203_RS10400	COG0006	proline dipeptidase activity
AO203_RS10410	COG0211	Belongs to the bacterial ribosomal protein bL27 family
AO203_RS10415	COG0261	This protein binds to 23S rRNA in the presence of protein L20
AO203_RS10425	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AO203_RS10435	COG1942	4-Oxalocrotonate Tautomerase
AO203_RS10480	COG2936	dipeptidyl-peptidase activity
AO203_RS10500	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
AO203_RS10500	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
AO203_RS10575	COG2801	Transposase and inactivated derivatives
AO203_RS10585	COG0505	Belongs to the CarA family
AO203_RS10590	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
AO203_RS10595	COG0540	Belongs to the ATCase OTCase family
AO203_RS10605	COG0167	dihydroorotate dehydrogenase activity
AO203_RS10610	COG0284	orotidine-5'-phosphate decarboxylase activity
AO203_RS10615	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
AO203_RS10645	COG1744	ABC transporter substrate-binding protein PnrA-like
AO203_RS10650	COG3845	ABC transporter
AO203_RS10655	COG4603	Belongs to the binding-protein-dependent transport system permease family
AO203_RS10660	COG1079	Belongs to the binding-protein-dependent transport system permease family
AO203_RS10665	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
AO203_RS10670	COG0038	chloride channel
AO203_RS10710	COG2151	metal-sulfur cluster biosynthetic enzyme
AO203_RS10715	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AO203_RS10725	COG0765	amino acid transport
AO203_RS10730	COG0765	amino acid transport
AO203_RS10795	COG1760	l-serine dehydratase
AO203_RS10800	COG1760	l-serine dehydratase
AO203_RS10805	COG2151	metal-sulfur cluster biosynthetic enzyme
AO203_RS10935	COG0431	NADPH-dependent FMN reductase
AO203_RS10990	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
AO203_RS11000	COG1854	S-ribosylhomocysteine lyase activity
AO203_RS11065	COG2017	converts alpha-aldose to the beta-anomer
AO203_RS11070	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
AO203_RS11075	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
AO203_RS11115	COG2848	UPF0210 protein
AO203_RS11120	COG3830	Belongs to the UPF0237 family
AO203_RS11145	COG2211	Major facilitator Superfamily
AO203_RS11145	COG2190	(PTS) system
AO203_RS11150	COG2190	(PTS) system
AO203_RS11150	COG2211	Major facilitator Superfamily
AO203_RS11155	COG2211	Major facilitator Superfamily
AO203_RS11155	COG2190	(PTS) system
AO203_RS11160	COG2211	Major facilitator Superfamily
AO203_RS11160	COG2190	(PTS) system
AO203_RS11165	COG2211	Major facilitator Superfamily
AO203_RS11165	COG2190	(PTS) system
AO203_RS11170	COG1609	Transcriptional regulator
AO203_RS11175	COG3250	beta-galactosidase activity
AO203_RS11180	COG3250	beta-galactosidase activity
AO203_RS11185	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AO203_RS11190	COG1609	Transcriptional regulator
AO203_RS11195	COG1609	Transcriptional regulator
AO203_RS11245	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
AO203_RS11250	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AO203_RS11265	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
AO203_RS11270	COG0267	Belongs to the bacterial ribosomal protein bL33 family
AO203_RS11275	COG0768	penicillin binding
AO203_RS11285	COG2971	BadF BadG BcrA BcrD
AO203_RS11320	COG0072	phenylalanine-tRNA ligase activity
AO203_RS11325	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
AO203_RS11330	COG1733	regulation of RNA biosynthetic process
AO203_RS11335	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AO203_RS11340	COG1254	Belongs to the acylphosphatase family
AO203_RS11345	COG0706	membrane insertase activity
AO203_RS11350	COG3760	aminoacyl-tRNA metabolism involved in translational fidelity
AO203_RS11355	COG5002	protein histidine kinase activity
AO203_RS11360	COG0745	RESPONSE REGULATOR receiver
AO203_RS11370	COG1323	Belongs to the UPF0348 family
AO203_RS11375	COG0799	negative regulation of ribosome biogenesis
AO203_RS11380	COG1713	HD superfamily hydrolase involved in NAD metabolism
AO203_RS11385	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
AO203_RS11390	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
AO203_RS11395	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
AO203_RS11400	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
AO203_RS11405	COG0291	Belongs to the bacterial ribosomal protein bL35 family
AO203_RS11410	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
AO203_RS11455	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
AO203_RS11460	COG1484	DNA-dependent DNA replication
AO203_RS11470	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
AO203_RS11475	COG0237	dephospho-CoA kinase activity
AO203_RS11480	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
AO203_RS11485	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AO203_RS11485	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AO203_RS11495	COG0477	Major facilitator Superfamily
AO203_RS11505	COG1846	Transcriptional regulator
AO203_RS11510	COG0151	Belongs to the GarS family
AO203_RS11515	COG0138	bifunctional purine biosynthesis protein purh
AO203_RS11520	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
AO203_RS11525	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
AO203_RS11535	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AO203_RS11540	COG0047	phosphoribosylformylglycinamidine synthase activity
AO203_RS11545	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AO203_RS11550	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
AO203_RS11565	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
AO203_RS11570	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
AO203_RS11575	COG2759	Belongs to the formate--tetrahydrofolate ligase family
AO203_RS11620	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AO203_RS11645	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AO203_RS11650	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AO203_RS11655	COG0220	tRNA (guanine-N7-)-methyltransferase activity
AO203_RS11665	COG1131	(ABC) transporter
AO203_RS11680	COG0537	adenosine 5'-monophosphoramidase activity
AO203_RS11690	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AO203_RS11705	COG3481	metal-dependent phosphohydrolase, HD sub domain
AO203_RS11715	COG0420	3'-5' exonuclease activity
AO203_RS11720	COG3679	Belongs to the UPF0342 family
AO203_RS11725	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AO203_RS11730	COG0564	pseudouridine synthase activity
AO203_RS11735	COG3708	Transcriptional regulator
AO203_RS11735	COG2207	Transcriptional regulator
AO203_RS11750	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
AO203_RS11755	COG2801	Transposase and inactivated derivatives
AO203_RS11850	COG1122	ATPase activity