locus-tag	class	description
FEE39_RS00015	COG1215	transferase activity, transferring glycosyl groups
FEE39_RS00020	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
FEE39_RS00040	COG1126	abc transporter atp-binding protein
FEE39_RS00045	COG0765	amino acid transport
FEE39_RS00050	COG2094	Belongs to the DNA glycosylase MPG family
FEE39_RS00055	COG3189	MarR family transcriptional regulator
FEE39_RS00060	COG0861	Integral membrane protein TerC family
FEE39_RS00065	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FEE39_RS00070	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
FEE39_RS00080	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FEE39_RS00085	COG2738	Putative neutral zinc metallopeptidase
FEE39_RS00095	COG0328	RNA-DNA hybrid ribonuclease activity
FEE39_RS00110	COG1216	Glycosyl transferase, family 2
FEE39_RS00115	COG2267	carboxylic ester hydrolase activity
FEE39_RS00125	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
FEE39_RS00135	COG1113	amino acid transport
FEE39_RS00155	COG1181	Belongs to the D-alanine--D-alanine ligase family
FEE39_RS00165	COG3344	reverse transcriptase
FEE39_RS00195	COG2188	Transcriptional regulator
FEE39_RS00200	COG2222	sugar isomerase
FEE39_RS00210	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FEE39_RS00220	COG3716	PTS system mannose fructose sorbose family IID component
FEE39_RS00225	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
FEE39_RS00225	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FEE39_RS00235	COG3613	nucleoside 2-deoxyribosyltransferase
FEE39_RS00250	COG2365	Tyrosine phosphatase family
FEE39_RS00255	COG0589	response to stress
FEE39_RS00280	COG3639	organic phosphonate transmembrane transporter activity
FEE39_RS00295	COG0367	asparagine synthase
FEE39_RS00305	COG1328	CTP reductase activity
FEE39_RS00310	COG0602	queuosine metabolic process
FEE39_RS00315	COG2151	metal-sulfur cluster biosynthetic enzyme
FEE39_RS00325	COG2814	Major facilitator Superfamily
FEE39_RS00330	COG3684	Belongs to the aldolase LacD family
FEE39_RS00350	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FEE39_RS00350	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FEE39_RS00350	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FEE39_RS00355	COG3590	peptidase
FEE39_RS00365	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
FEE39_RS00370	COG3158	transport of potassium into the cell
FEE39_RS00375	COG3158	transport of potassium into the cell
FEE39_RS00400	COG1705	Flagellar rod assembly protein muramidase FlgJ
FEE39_RS00400	COG1388	LysM domain
FEE39_RS00415	COG0569	domain protein
FEE39_RS00415	COG0475	glutathione-regulated potassium exporter activity
FEE39_RS00420	COG0673	inositol 2-dehydrogenase activity
FEE39_RS00440	COG0588	phosphoglycerate mutase activity
FEE39_RS00445	COG1598	PFAM Uncharacterised protein family UPF0150
FEE39_RS00450	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
FEE39_RS00470	COG4975	Glucose uptake
FEE39_RS00480	COG1316	TRANSCRIPTIONal
FEE39_RS00485	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
FEE39_RS00490	COG1368	sulfuric ester hydrolase activity
FEE39_RS00495	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FEE39_RS00505	COG3579	cysteine-type endopeptidase activity
FEE39_RS00510	COG1418	mRNA catabolic process
FEE39_RS00525	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FEE39_RS00550	COG2188	Transcriptional regulator
FEE39_RS00560	COG2723	6-phospho-beta-galactosidase activity
FEE39_RS00565	COG2188	Transcriptional regulator
FEE39_RS00570	COG1447	Phosphotransferase system cellobiose-specific component IIA
FEE39_RS00580	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FEE39_RS00585	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FEE39_RS00590	COG2723	6-phospho-beta-galactosidase activity
FEE39_RS00620	COG2131	deaminase
FEE39_RS00630	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
FEE39_RS00640	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FEE39_RS00640	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FEE39_RS00645	COG0084	hydrolase, TatD family'
FEE39_RS00655	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
FEE39_RS00660	COG4466	Protein conserved in bacteria
FEE39_RS00665	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FEE39_RS00670	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
FEE39_RS00675	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
FEE39_RS00680	COG1609	Transcriptional regulator
FEE39_RS00685	COG0366	Alpha amylase catalytic
FEE39_RS00700	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FEE39_RS00705	COG3842	ATPase activity
FEE39_RS00710	COG1653	transport
FEE39_RS00715	COG1175	transmembrane transport
FEE39_RS00720	COG3833	ABC-type maltose transport systems, permease component
FEE39_RS00725	COG3344	reverse transcriptase
FEE39_RS00730	COG0366	Alpha amylase catalytic
FEE39_RS00735	COG1078	dGTPase activity
FEE39_RS00745	COG3343	RNA polymerase activity
FEE39_RS00750	COG0504	CTP synthase activity
FEE39_RS00755	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
FEE39_RS00760	COG2233	PERMEase
FEE39_RS00765	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FEE39_RS00785	COG0519	Catalyzes the synthesis of GMP from XMP
FEE39_RS00790	COG1733	regulation of RNA biosynthetic process
FEE39_RS00810	COG1881	PFAM PEBP family protein
FEE39_RS00820	COG1396	sequence-specific DNA binding
FEE39_RS00825	COG2249	NAD(P)H dehydrogenase (quinone) activity
FEE39_RS00875	COG0456	acetyltransferase
FEE39_RS00890	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FEE39_RS00895	COG0028	Belongs to the TPP enzyme family
FEE39_RS00900	COG0679	Auxin Efflux Carrier
FEE39_RS00920	COG1733	regulation of RNA biosynthetic process
FEE39_RS00930	COG3344	reverse transcriptase
FEE39_RS00935	COG0778	Nitroreductase
FEE39_RS00940	COG4690	dipeptidase activity
FEE39_RS00945	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
FEE39_RS00955	COG4120	Belongs to the binding-protein-dependent transport system permease family
FEE39_RS00965	COG0531	amino acid
FEE39_RS00970	COG0254	rRNA binding
FEE39_RS00975	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
FEE39_RS00985	COG0736	holo-[acyl-carrier-protein] synthase activity
FEE39_RS01000	COG0039	L-malate dehydrogenase activity
FEE39_RS01005	COG0193	aminoacyl-tRNA hydrolase activity
FEE39_RS01010	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
FEE39_RS01015	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
FEE39_RS01025	COG1185	polyribonucleotide nucleotidyltransferase activity
FEE39_RS01030	COG0037	tRNA processing
FEE39_RS01050	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
FEE39_RS01055	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FEE39_RS01060	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
FEE39_RS01070	COG3344	reverse transcriptase
FEE39_RS01080	COG0542	response to heat
FEE39_RS01090	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
FEE39_RS01105	COG0049	tRNA binding
FEE39_RS01110	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
FEE39_RS01120	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
FEE39_RS01125	COG0088	Forms part of the polypeptide exit tunnel
FEE39_RS01130	COG0089	rRNA binding
FEE39_RS01135	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
FEE39_RS01150	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
FEE39_RS01155	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
FEE39_RS01160	COG0255	Belongs to the universal ribosomal protein uL29 family
FEE39_RS01175	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
FEE39_RS01180	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
FEE39_RS01190	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
FEE39_RS01195	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
FEE39_RS01200	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
FEE39_RS01215	COG0200	Binds to the 23S rRNA
FEE39_RS01225	COG0563	adenylate kinase activity
FEE39_RS01230	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
FEE39_RS01250	COG0202	RNA polymerase activity
FEE39_RS01255	COG0203	ribosomal protein L17
FEE39_RS01260	COG1122	ATPase activity
FEE39_RS01265	COG1122	ATPase activity
FEE39_RS01270	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
FEE39_RS01275	COG0101	tRNA pseudouridine synthase activity
FEE39_RS01280	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
FEE39_RS01295	COG1132	(ABC) transporter
FEE39_RS01320	COG0640	Transcriptional regulator
FEE39_RS01340	COG0588	phosphoglycerate mutase activity
FEE39_RS01365	COG0531	amino acid
FEE39_RS01375	COG0201	protein transport
FEE39_RS01385	COG1073	alpha beta
FEE39_RS01395	COG0653	protein targeting
FEE39_RS01440	COG1216	Glycosyl transferase, family 2
FEE39_RS01440	COG1442	glycosyl transferase family 8
FEE39_RS01450	COG0438	transferase activity, transferring glycosyl groups
FEE39_RS01465	COG0756	dUTP diphosphatase activity
FEE39_RS01475	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FEE39_RS01480	COG0215	cysteine-tRNA ligase activity
FEE39_RS01485	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
FEE39_RS01490	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FEE39_RS01505	COG1070	Carbohydrate kinase
FEE39_RS01510	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
FEE39_RS01520	COG0142	geranyltranstransferase activity
FEE39_RS01535	COG0250	Participates in transcription elongation, termination and antitermination
FEE39_RS01540	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
FEE39_RS01545	COG0081	regulation of translation
FEE39_RS01550	COG0765	amino acid transport
FEE39_RS01555	COG1126	abc transporter atp-binding protein
FEE39_RS01560	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FEE39_RS01565	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
FEE39_RS01585	COG2813	Specifically methylates the guanine in position
FEE39_RS01595	COG0590	tRNA wobble adenosine to inosine editing
FEE39_RS01605	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
FEE39_RS01610	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
FEE39_RS01625	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
FEE39_RS01630	COG3870	Protein conserved in bacteria
FEE39_RS01640	COG4467	Involved in initiation control of chromosome replication
FEE39_RS01655	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
FEE39_RS01660	COG1214	PFAM Peptidase M22, glycoprotease
FEE39_RS01670	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
FEE39_RS01705	COG0516	GMP reductase activity
FEE39_RS01710	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
FEE39_RS01715	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
FEE39_RS01720	COG0494	nUDIX hydrolase
FEE39_RS01730	COG3344	reverse transcriptase
FEE39_RS01775	COG1653	transport
FEE39_RS01785	COG0488	(ABC) transporter
FEE39_RS01835	COG0459	protein refolding
FEE39_RS01875	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
FEE39_RS01880	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
FEE39_RS01885	COG0632	four-way junction helicase activity
FEE39_RS01890	COG2255	four-way junction helicase activity
FEE39_RS01895	COG1862	Preprotein translocase
FEE39_RS01900	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
FEE39_RS01905	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FEE39_RS01910	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
FEE39_RS01915	COG0513	Belongs to the DEAD box helicase family
FEE39_RS01920	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FEE39_RS01930	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
FEE39_RS01935	COG3906	Belongs to the UPF0473 family
FEE39_RS01945	COG1193	negative regulation of DNA recombination
FEE39_RS01950	COG3118	belongs to the thioredoxin family
FEE39_RS01955	COG3344	reverse transcriptase
FEE39_RS01960	COG1719	4-vinyl reductase, 4VR
FEE39_RS01965	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
FEE39_RS01970	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
FEE39_RS01975	COG3344	reverse transcriptase
FEE39_RS01980	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
FEE39_RS01985	COG0668	transmembrane transport
FEE39_RS02000	COG0006	proline dipeptidase activity
FEE39_RS02020	COG0584	glycerophosphoryl diester phosphodiesterase
FEE39_RS02030	COG0737	Belongs to the 5'-nucleotidase family
FEE39_RS02040	COG0647	UMP catabolic process
FEE39_RS02050	COG0586	Pfam SNARE associated Golgi protein
FEE39_RS02055	COG0492	ferredoxin-NADP+ reductase activity
FEE39_RS02060	COG1098	S1 RNA binding domain
FEE39_RS02100	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
FEE39_RS02105	COG0477	Major facilitator Superfamily
FEE39_RS02120	COG0495	leucyl-tRNA aminoacylation
FEE39_RS02125	COG2244	polysaccharide biosynthetic process
FEE39_RS02140	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
FEE39_RS02145	COG1686	Belongs to the peptidase S11 family
FEE39_RS02150	COG0018	arginyl-trna synthetase
FEE39_RS02180	COG3715	PTS system
FEE39_RS02185	COG3716	PTS system mannose fructose sorbose family IID component
FEE39_RS02190	COG1285	pathogenesis
FEE39_RS02195	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
FEE39_RS02215	COG0675	Transposase, IS605 OrfB family
FEE39_RS02225	COG1956	GAF domain-containing protein
FEE39_RS02240	COG0519	Catalyzes the synthesis of GMP from XMP
FEE39_RS02255	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
FEE39_RS02260	COG2814	Major facilitator Superfamily
FEE39_RS02265	COG2814	Major facilitator Superfamily
FEE39_RS02270	COG0456	acetyltransferase
FEE39_RS02280	COG0561	phosphatase activity
FEE39_RS02290	COG0561	phosphatase activity
FEE39_RS02295	COG4977	sequence-specific DNA binding
FEE39_RS02305	COG1349	DNA-binding transcription factor activity
FEE39_RS02310	COG0698	ribose 5-phosphate isomerase
FEE39_RS02325	COG1447	Phosphotransferase system cellobiose-specific component IIA
FEE39_RS02330	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FEE39_RS02330	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FEE39_RS02360	COG0531	amino acid
FEE39_RS02370	COG3579	cysteine-type endopeptidase activity
FEE39_RS02375	COG0531	amino acid
FEE39_RS02390	COG0531	amino acid
FEE39_RS02420	COG4619	ABC transporter
FEE39_RS02425	COG0390	transport system, permease component
FEE39_RS02445	COG1874	Beta-galactosidase
FEE39_RS02450	COG3104	oligopeptide transport
FEE39_RS02460	COG2814	Major facilitator Superfamily
FEE39_RS02475	COG1132	(ABC) transporter
FEE39_RS02480	COG1132	(ABC) transporter
FEE39_RS02485	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FEE39_RS02495	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FEE39_RS02500	COG0765	amino acid transport
FEE39_RS02505	COG0765	amino acid transport
FEE39_RS02530	COG0572	uridine kinase
FEE39_RS02565	COG2274	protein secretion by the type I secretion system
FEE39_RS02650	COG0765	amino acid transport
FEE39_RS02655	COG1126	abc transporter atp-binding protein
FEE39_RS02670	COG0573	inorganic phosphate transmembrane transporter activity
FEE39_RS02675	COG0581	inorganic phosphate transmembrane transporter activity
FEE39_RS02680	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FEE39_RS02685	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FEE39_RS02690	COG0704	Plays a role in the regulation of phosphate uptake
FEE39_RS02695	COG3344	reverse transcriptase
FEE39_RS02700	COG1288	antiporter activity
FEE39_RS02705	COG0783	Belongs to the Dps family
FEE39_RS02715	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
FEE39_RS02725	COG2188	Transcriptional regulator
FEE39_RS02740	COG1132	(ABC) transporter
FEE39_RS02765	COG1253	flavin adenine dinucleotide binding
FEE39_RS02775	COG0531	amino acid
FEE39_RS02790	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FEE39_RS02800	COG3344	reverse transcriptase
FEE39_RS02805	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
FEE39_RS02815	COG0716	FMN binding
FEE39_RS02820	COG0024	Methionine aminopeptidase
FEE39_RS02830	COG1210	Utp--glucose-1-phosphate uridylyltransferase
FEE39_RS02835	COG0517	IMP dehydrogenase activity
FEE39_RS02835	COG1125	glycine betaine transport
FEE39_RS02860	COG2357	RelA SpoT domain protein
FEE39_RS02865	COG0745	RESPONSE REGULATOR receiver
FEE39_RS02870	COG5002	protein histidine kinase activity
FEE39_RS02875	COG2936	dipeptidyl-peptidase activity
FEE39_RS02880	COG0308	aminopeptidase N
FEE39_RS02885	COG0561	phosphatase activity
FEE39_RS02895	COG1132	(ABC) transporter
FEE39_RS02900	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FEE39_RS02925	COG2814	Major facilitator Superfamily
FEE39_RS02935	COG4166	transmembrane transport
FEE39_RS02945	COG3579	cysteine-type endopeptidase activity
FEE39_RS03020	COG1942	4-Oxalocrotonate Tautomerase
FEE39_RS03040	COG1393	Belongs to the ArsC family
FEE39_RS03045	COG0261	This protein binds to 23S rRNA in the presence of protein L20
FEE39_RS03050	COG0211	Belongs to the bacterial ribosomal protein bL27 family
FEE39_RS03055	COG0006	proline dipeptidase activity
FEE39_RS03060	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
FEE39_RS03070	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FEE39_RS03075	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
FEE39_RS03080	COG1570	exodeoxyribonuclease VII activity
FEE39_RS03085	COG1722	exodeoxyribonuclease VII activity
FEE39_RS03095	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
FEE39_RS03100	COG0497	DNA recombination
FEE39_RS03115	COG0194	GDP metabolic process
FEE39_RS03120	COG1758	RNA polymerase activity
FEE39_RS03125	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
FEE39_RS03130	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
FEE39_RS03135	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FEE39_RS03135	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FEE39_RS03140	COG0631	protein serine/threonine phosphatase activity
FEE39_RS03145	COG2815	serine threonine protein kinase
FEE39_RS03145	COG0515	serine threonine protein kinase
FEE39_RS03150	COG1162	GTPase activity
FEE39_RS03155	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
FEE39_RS03160	COG1564	THIamine pyrophosphokinase
FEE39_RS03165	COG0227	Belongs to the bacterial ribosomal protein bL28 family
FEE39_RS03175	COG1461	Dihydroxyacetone kinase
FEE39_RS03180	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
FEE39_RS03185	COG0416	fatty acid biosynthetic process
FEE39_RS03190	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FEE39_RS03200	COG4608	Belongs to the ABC transporter superfamily
FEE39_RS03205	COG0601	transmembrane transport
FEE39_RS03210	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FEE39_RS03225	COG0571	ribonuclease III activity
FEE39_RS03230	COG1196	nuclear chromosome segregation
FEE39_RS03235	COG0552	protein localization to endoplasmic reticulum
FEE39_RS03245	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
FEE39_RS03250	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
FEE39_RS03255	COG0228	four-way junction DNA binding
FEE39_RS03260	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
FEE39_RS03265	COG0336	Belongs to the RNA methyltransferase TrmD family
FEE39_RS03280	COG0494	nUDIX hydrolase
FEE39_RS03290	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
FEE39_RS03295	COG4224	UPF0291 protein
FEE39_RS03300	COG3763	UPF0154 protein
FEE39_RS03305	COG1132	(ABC) transporter
FEE39_RS03310	COG1132	(ABC) transporter
FEE39_RS03320	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FEE39_RS03325	COG0204	Acyl-transferase
FEE39_RS03330	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
FEE39_RS03335	COG0052	Belongs to the universal ribosomal protein uS2 family
FEE39_RS03340	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
FEE39_RS03345	COG0528	UMP kinase activity
FEE39_RS03350	COG0233	cytoplasmic translational termination
FEE39_RS03355	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
FEE39_RS03360	COG4589	Belongs to the CDS family
FEE39_RS03365	COG0750	zinc metalloprotease
FEE39_RS03370	COG0442	prolyl-tRNA aminoacylation
FEE39_RS03380	COG0779	Required for maturation of 30S ribosomal subunits
FEE39_RS03385	COG0195	Participates in both transcription termination and antitermination
FEE39_RS03390	COG2740	Nucleic-acid-binding protein implicated in transcription termination
FEE39_RS03400	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
FEE39_RS03405	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
FEE39_RS03410	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
FEE39_RS03415	COG0196	riboflavin kinase activity
FEE39_RS03420	COG0488	(ABC) transporter
FEE39_RS03440	COG1420	regulation of RNA biosynthetic process
FEE39_RS03445	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
FEE39_RS03450	COG0443	Heat shock 70 kDa protein
FEE39_RS03455	COG0484	heat shock protein binding
FEE39_RS03460	COG0481	GTPase activity
FEE39_RS03465	COG3764	Sortase (surface protein transpeptidase)
FEE39_RS03470	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
FEE39_RS03470	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
FEE39_RS03475	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FEE39_RS03485	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FEE39_RS03490	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
FEE39_RS03495	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
FEE39_RS03510	COG0583	DNA-binding transcription factor activity
FEE39_RS03525	COG0148	phosphopyruvate hydratase activity
FEE39_RS03535	COG0488	(ABC) transporter
FEE39_RS03565	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FEE39_RS03570	COG2011	ABC-type metal ion transport system permease component
FEE39_RS03575	COG0114	fumarate hydratase activity
FEE39_RS03580	COG1053	succinate dehydrogenase
FEE39_RS03585	COG0039	L-malate dehydrogenase activity
FEE39_RS03595	COG0252	asparaginase activity
FEE39_RS03600	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
FEE39_RS03610	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
FEE39_RS03615	COG2264	protein methyltransferase activity
FEE39_RS03625	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FEE39_RS03630	COG1490	D-aminoacyl-tRNA deacylase activity
FEE39_RS03635	COG0124	histidyl-tRNA synthetase
FEE39_RS03640	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
FEE39_RS03650	COG0436	Aminotransferase
FEE39_RS03665	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FEE39_RS03670	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FEE39_RS03675	COG1760	l-serine dehydratase
FEE39_RS03680	COG1760	l-serine dehydratase
FEE39_RS03685	COG2151	metal-sulfur cluster biosynthetic enzyme
FEE39_RS03690	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
FEE39_RS03695	COG0828	Belongs to the bacterial ribosomal protein bS21 family
FEE39_RS03700	COG1610	YqeY-like protein
FEE39_RS03705	COG1702	phosphate starvation-inducible protein PhoH
FEE39_RS03710	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
FEE39_RS03715	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
FEE39_RS03720	COG1381	Involved in DNA repair and RecF pathway recombination
FEE39_RS03725	COG0752	glycyl-tRNA synthetase alpha subunit
FEE39_RS03730	COG0751	glycine-tRNA ligase activity
FEE39_RS03735	COG0305	Participates in initiation and elongation during chromosome replication
FEE39_RS03735	COG0358	DNA primase activity
FEE39_RS03740	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FEE39_RS03750	COG0765	amino acid transport
FEE39_RS03755	COG0765	amino acid transport
FEE39_RS03760	COG1126	abc transporter atp-binding protein
FEE39_RS03770	COG2384	SAM-dependent methyltransferase
FEE39_RS03775	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
FEE39_RS03780	COG2195	Cleaves the N-terminal amino acid of tripeptides
FEE39_RS03785	COG1725	Transcriptional regulator
FEE39_RS03790	COG1131	(ABC) transporter
FEE39_RS03825	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FEE39_RS03825	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
FEE39_RS03830	COG0393	Putative heavy-metal-binding
FEE39_RS03835	COG1434	Gram-negative-bacterium-type cell wall biogenesis
FEE39_RS03850	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
FEE39_RS03855	COG0284	orotidine-5'-phosphate decarboxylase activity
FEE39_RS03860	COG0167	dihydroorotate dehydrogenase activity
FEE39_RS03870	COG0540	Belongs to the ATCase OTCase family
FEE39_RS03875	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
FEE39_RS03880	COG0505	Belongs to the CarA family
FEE39_RS03885	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
FEE39_RS03895	COG1335	isochorismatase
FEE39_RS03900	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
FEE39_RS03915	COG1136	(ABC) transporter
FEE39_RS03925	COG3590	peptidase
FEE39_RS03930	COG0778	Nitroreductase
FEE39_RS03945	COG1929	Belongs to the glycerate kinase type-1 family
FEE39_RS03960	COG2274	protein secretion by the type I secretion system
FEE39_RS03965	COG1132	(ABC) transporter
FEE39_RS03970	COG0148	phosphopyruvate hydratase activity
FEE39_RS03985	COG1132	(ABC) transporter
FEE39_RS04000	COG3077	Addiction module antitoxin, RelB DinJ family
FEE39_RS04040	COG2365	Tyrosine phosphatase family
FEE39_RS04065	COG0456	acetyltransferase
FEE39_RS04125	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
FEE39_RS04130	COG1869	D-ribose catabolic process
FEE39_RS04135	COG4975	Glucose uptake
FEE39_RS04155	COG1132	(ABC) transporter
FEE39_RS04180	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
FEE39_RS04185	COG1074	ATP-dependent DNA helicase activity
FEE39_RS04190	COG1199	ATP-dependent helicase activity
FEE39_RS04190	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FEE39_RS04200	COG0017	Asparaginyl-tRNA synthetase
FEE39_RS04205	COG3935	DnaD domain protein
FEE39_RS04210	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
FEE39_RS04225	COG3331	DNA recombination
FEE39_RS04230	COG4474	Belongs to the UPF0398 family
FEE39_RS04235	COG3599	regulation of cell shape
FEE39_RS04245	COG0116	Belongs to the methyltransferase superfamily
FEE39_RS04260	COG1307	EDD domain protein, DegV family
FEE39_RS04270	COG2759	Belongs to the formate--tetrahydrofolate ligase family
FEE39_RS04275	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
FEE39_RS04280	COG0564	pseudouridine synthase activity
FEE39_RS04310	COG1307	EDD domain protein, DegV family
FEE39_RS04320	COG0583	DNA-binding transcription factor activity
FEE39_RS04325	COG4974	Belongs to the 'phage' integrase family
FEE39_RS04340	COG0514	ATP-dependent DNA helicase (RecQ)
FEE39_RS04345	COG1227	inorganic diphosphatase activity
FEE39_RS04350	COG0583	DNA-binding transcription factor activity
FEE39_RS04355	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FEE39_RS04360	COG0187	DNA topoisomerase II activity
FEE39_RS04365	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
FEE39_RS04370	COG0110	maltose O-acetyltransferase activity
FEE39_RS04395	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
FEE39_RS04405	COG0656	L-ascorbic acid biosynthetic process
FEE39_RS04410	COG1132	(ABC) transporter
FEE39_RS04420	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
FEE39_RS04430	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
FEE39_RS04445	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
FEE39_RS04455	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
FEE39_RS04475	COG1914	H( )-stimulated, divalent metal cation uptake system
FEE39_RS04485	COG0719	Fe-S assembly protein
FEE39_RS04495	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
FEE39_RS04500	COG0719	Fe-S assembly protein
FEE39_RS04505	COG0396	ATPase activity
FEE39_RS04510	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
FEE39_RS04515	COG0436	Aminotransferase
FEE39_RS04520	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
FEE39_RS04525	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FEE39_RS04530	COG1473	amidohydrolase
FEE39_RS04535	COG2171	N-acyltransferase activity
FEE39_RS04540	COG0019	diaminopimelate decarboxylase activity
FEE39_RS04545	COG0527	aspartate kinase activity
FEE39_RS04565	COG1114	Component of the transport system for branched-chain amino acids
FEE39_RS04585	COG5002	protein histidine kinase activity
FEE39_RS04590	COG0745	RESPONSE REGULATOR receiver
FEE39_RS04595	COG1051	belongs to the nudix hydrolase family
FEE39_RS04600	COG1011	Hydrolase
FEE39_RS04630	COG3527	Alpha-acetolactate decarboxylase
FEE39_RS04635	COG0028	Belongs to the TPP enzyme family
FEE39_RS04655	COG2855	membrane
FEE39_RS04680	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
FEE39_RS04695	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
FEE39_RS04700	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FEE39_RS04705	COG0758	DNA mediated transformation
FEE39_RS04710	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
FEE39_RS04715	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
FEE39_RS04720	COG0793	Belongs to the peptidase S41A family
FEE39_RS04720	COG3409	Peptidoglycan-binding domain 1 protein
FEE39_RS04725	COG4479	Belongs to the UPF0346 family
FEE39_RS04730	COG1307	EDD domain protein, DegV family
FEE39_RS04735	COG1272	protein, Hemolysin III
FEE39_RS04740	COG0617	tRNA 3'-terminal CCA addition
FEE39_RS04745	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FEE39_RS04795	COG0732	type I restriction modification DNA specificity domain
FEE39_RS04800	COG0732	type I restriction modification DNA specificity domain
FEE39_RS04825	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
FEE39_RS04840	COG1160	GTP binding
FEE39_RS04845	COG0539	negative regulation of cytoplasmic translation
FEE39_RS04850	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
FEE39_RS04855	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
FEE39_RS04865	COG1187	pseudouridine synthase activity
FEE39_RS04870	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
FEE39_RS04875	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
FEE39_RS04880	COG0456	acetyltransferase
FEE39_RS04890	COG2996	Protein conserved in bacteria
FEE39_RS04900	COG0205	6-phosphofructokinase activity
FEE39_RS04905	COG0587	DNA-directed DNA polymerase activity
FEE39_RS04915	COG0737	Belongs to the 5'-nucleotidase family
FEE39_RS04920	COG0333	Belongs to the bacterial ribosomal protein bL32 family
FEE39_RS04930	COG0300	oxidoreductase activity
FEE39_RS04935	COG1234	tRNA 3'-trailer cleavage
FEE39_RS04940	COG2755	lipolytic protein G-D-S-L family
FEE39_RS04940	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
FEE39_RS04945	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
FEE39_RS04950	COG0322	excinuclease ABC activity
FEE39_RS04955	COG1957	nucleoside hydrolase
FEE39_RS04960	COG0586	Pfam SNARE associated Golgi protein
FEE39_RS05025	COG1091	dTDP-4-dehydrorhamnose reductase activity
FEE39_RS05030	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
FEE39_RS05040	COG1088	dTDP-glucose 4,6-dehydratase activity
FEE39_RS05045	COG2226	methyltransferase
FEE39_RS05085	COG0438	transferase activity, transferring glycosyl groups
FEE39_RS05085	COG4641	Protein conserved in bacteria
FEE39_RS05090	COG1216	Glycosyl transferase, family 2
FEE39_RS05090	COG1442	glycosyl transferase family 8
FEE39_RS05095	COG0438	transferase activity, transferring glycosyl groups
FEE39_RS05100	COG0438	transferase activity, transferring glycosyl groups
FEE39_RS05105	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FEE39_RS05115	COG0489	protein tyrosine kinase activity
FEE39_RS05165	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
FEE39_RS05175	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FEE39_RS05185	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
FEE39_RS05195	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FEE39_RS05210	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
FEE39_RS05215	COG0268	Binds directly to 16S ribosomal RNA
FEE39_RS05225	COG1466	dna polymerase III delta subunit
FEE39_RS05235	COG1596	polysaccharide export
FEE39_RS05235	COG1555	photosystem II stabilization
FEE39_RS05240	COG3480	Lon protease (S16) C-terminal proteolytic domain
FEE39_RS05245	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
FEE39_RS05250	COG0742	ribosomal rna small subunit methyltransferase
FEE39_RS05260	COG0772	Belongs to the SEDS family
FEE39_RS05270	COG0242	peptide deformylase activity
FEE39_RS05285	COG1597	lipid kinase activity
FEE39_RS05290	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FEE39_RS05305	COG0482	sulfurtransferase activity
FEE39_RS05315	COG1104	cysteine desulfurase activity
FEE39_RS05330	COG0494	nUDIX hydrolase
FEE39_RS05335	COG1278	Cold shock
FEE39_RS05340	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
FEE39_RS05345	COG3599	regulation of cell shape
FEE39_RS05360	COG1799	cell septum assembly
FEE39_RS05365	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
FEE39_RS05375	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
FEE39_RS05380	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
FEE39_RS05385	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
FEE39_RS05390	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FEE39_RS05405	COG0275	rRNA processing
FEE39_RS05410	COG2001	Belongs to the MraZ family
FEE39_RS05435	COG1077	Cell shape determining protein MreB Mrl
FEE39_RS05440	COG2003	Belongs to the UPF0758 family
FEE39_RS05445	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FEE39_RS05455	COG0525	valine-tRNA ligase activity
FEE39_RS05460	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
FEE39_RS05470	COG1187	pseudouridine synthase activity
FEE39_RS05475	COG0301	tRNA thio-modification
FEE39_RS05480	COG1104	cysteine desulfurase activity
FEE39_RS05485	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
FEE39_RS05500	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
FEE39_RS05515	COG0772	Belongs to the SEDS family
FEE39_RS05525	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
FEE39_RS05535	COG1077	Cell shape determining protein MreB Mrl
FEE39_RS05545	COG0355	proton-transporting ATP synthase activity, rotational mechanism
FEE39_RS05550	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
FEE39_RS05555	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
FEE39_RS05565	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
FEE39_RS05570	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
FEE39_RS05575	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
FEE39_RS05580	COG0356	it plays a direct role in the translocation of protons across the membrane
FEE39_RS05590	COG0009	L-threonylcarbamoyladenylate synthase
FEE39_RS05595	COG2890	protein-(glutamine-N5) methyltransferase activity
FEE39_RS05600	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
FEE39_RS05605	COG1435	thymidine kinase activity
FEE39_RS05610	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
FEE39_RS05615	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FEE39_RS05635	COG0477	Major facilitator Superfamily
FEE39_RS05640	COG0166	Belongs to the GPI family
FEE39_RS05650	COG1368	sulfuric ester hydrolase activity
FEE39_RS05655	COG3344	reverse transcriptase
FEE39_RS05660	COG5002	protein histidine kinase activity
FEE39_RS05660	COG3850	Histidine kinase
FEE39_RS05665	COG0745	RESPONSE REGULATOR receiver
FEE39_RS05675	COG1482	cell wall glycoprotein biosynthetic process
FEE39_RS05690	COG1621	beta-fructofuranosidase activity
FEE39_RS05700	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
FEE39_RS05705	COG0827	DNA restriction-modification system
FEE39_RS05725	COG4537	Required for transformation and DNA binding
FEE39_RS05735	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FEE39_RS05740	COG0217	transcriptional regulatory protein
FEE39_RS05750	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
FEE39_RS05760	COG2267	carboxylic ester hydrolase activity
FEE39_RS05775	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
FEE39_RS05780	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
FEE39_RS05785	COG0561	phosphatase activity
FEE39_RS05790	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FEE39_RS05800	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
FEE39_RS05810	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
FEE39_RS05820	COG3842	ATPase activity
FEE39_RS05825	COG0812	UDP-N-acetylmuramate dehydrogenase activity
FEE39_RS05835	COG0802	atpase or kinase
FEE39_RS05840	COG0280	phosphate acetyltransferase
FEE39_RS05845	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
FEE39_RS05850	COG0561	phosphatase activity
FEE39_RS05870	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
FEE39_RS05875	COG0557	exoribonuclease II activity
FEE39_RS05885	COG0148	phosphopyruvate hydratase activity
FEE39_RS05890	COG0149	triose-phosphate isomerase activity
FEE39_RS05895	COG0126	phosphoglycerate kinase activity
FEE39_RS05905	COG2390	Transcriptional regulator
FEE39_RS05910	COG0531	amino acid
FEE39_RS05920	COG1481	regulation of sporulation
FEE39_RS05930	COG1660	Displays ATPase and GTPase activities
FEE39_RS05945	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
FEE39_RS05950	COG0556	nucleotide-excision repair
FEE39_RS05955	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FEE39_RS05960	COG2017	converts alpha-aldose to the beta-anomer
FEE39_RS05965	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
FEE39_RS05970	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
FEE39_RS05975	COG1874	Beta-galactosidase
FEE39_RS05980	COG2190	(PTS) system
FEE39_RS05980	COG2211	Major facilitator Superfamily
FEE39_RS05985	COG1609	Transcriptional regulator
FEE39_RS05990	COG3250	beta-galactosidase activity
FEE39_RS05995	COG3250	beta-galactosidase activity
FEE39_RS06000	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FEE39_RS06005	COG0492	ferredoxin-NADP+ reductase activity
FEE39_RS06010	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
FEE39_RS06015	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
FEE39_RS06020	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
FEE39_RS06035	COG0653	protein targeting
FEE39_RS06050	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
FEE39_RS06055	COG1739	Uncharacterized protein family UPF0029
FEE39_RS06065	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FEE39_RS06070	COG1418	mRNA catabolic process
FEE39_RS06075	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
FEE39_RS06085	COG1426	Protein conserved in bacteria
FEE39_RS06090	COG1028	Short-chain dehydrogenase reductase Sdr
FEE39_RS06095	COG0612	Peptidase, M16
FEE39_RS06105	COG1674	ftsk spoiiie
FEE39_RS06105	COG1280	lysine exporter protein (LysE YggA)
FEE39_RS06120	COG0628	permease
FEE39_RS06130	COG2706	6-phosphogluconolactonase activity
FEE39_RS06145	COG0564	pseudouridine synthase activity
FEE39_RS06150	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
FEE39_RS06155	COG2357	RelA SpoT domain protein
FEE39_RS06160	COG4116	CYTH
FEE39_RS06180	COG1393	Belongs to the ArsC family
FEE39_RS06185	COG3344	reverse transcriptase
FEE39_RS06195	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FEE39_RS06205	COG0542	response to heat
FEE39_RS06215	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
FEE39_RS06220	COG1253	flavin adenine dinucleotide binding
FEE39_RS06235	COG3557	Belongs to the UPF0374 family
FEE39_RS06240	COG2137	regulation of response to DNA damage stimulus
FEE39_RS06245	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FEE39_RS06250	COG3425	synthase
FEE39_RS06260	COG0183	Belongs to the thiolase family
FEE39_RS06275	COG0561	phosphatase activity
FEE39_RS06280	COG2814	Major facilitator Superfamily
FEE39_RS06290	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
FEE39_RS06320	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
FEE39_RS06330	COG0768	penicillin binding
FEE39_RS06345	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
FEE39_RS06350	COG0072	phenylalanine-tRNA ligase activity
FEE39_RS06355	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
FEE39_RS06360	COG1733	regulation of RNA biosynthetic process
FEE39_RS06365	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FEE39_RS06370	COG1254	Belongs to the acylphosphatase family
FEE39_RS06375	COG0706	membrane insertase activity
FEE39_RS06380	COG5002	protein histidine kinase activity
FEE39_RS06395	COG1323	Belongs to the UPF0348 family
FEE39_RS06400	COG0799	negative regulation of ribosome biogenesis
FEE39_RS06405	COG1713	HD superfamily hydrolase involved in NAD metabolism
FEE39_RS06410	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
FEE39_RS06415	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
FEE39_RS06420	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
FEE39_RS06425	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
FEE39_RS06430	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
FEE39_RS06440	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
FEE39_RS06450	COG1126	abc transporter atp-binding protein
FEE39_RS06465	COG3344	reverse transcriptase
FEE39_RS06470	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
FEE39_RS06475	COG1484	DNA-dependent DNA replication
FEE39_RS06485	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
FEE39_RS06490	COG0237	dephospho-CoA kinase activity
FEE39_RS06495	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
FEE39_RS06500	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FEE39_RS06500	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FEE39_RS06520	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
FEE39_RS06520	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FEE39_RS06530	COG4213	ABC transporter substrate-binding protein
FEE39_RS06535	COG4585	Histidine kinase
FEE39_RS06540	COG2197	response regulator
FEE39_RS06550	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
FEE39_RS06560	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FEE39_RS06565	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FEE39_RS06570	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FEE39_RS06580	COG0220	tRNA (guanine-N7-)-methyltransferase activity
FEE39_RS06590	COG1131	(ABC) transporter
FEE39_RS06595	COG0537	adenosine 5'-monophosphoramidase activity
FEE39_RS06610	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FEE39_RS06615	COG3344	reverse transcriptase
FEE39_RS06620	COG3481	metal-dependent phosphohydrolase, HD sub domain
FEE39_RS06630	COG0420	3'-5' exonuclease activity
FEE39_RS06635	COG3679	Belongs to the UPF0342 family
FEE39_RS06640	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FEE39_RS06645	COG0564	pseudouridine synthase activity
FEE39_RS06665	COG1051	belongs to the nudix hydrolase family
FEE39_RS06670	COG3231	kanamycin kinase activity
FEE39_RS06680	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FEE39_RS06690	COG1131	(ABC) transporter
FEE39_RS06720	COG1442	glycosyl transferase family 8
FEE39_RS06725	COG1442	glycosyl transferase family 8
FEE39_RS06750	COG0561	phosphatase activity
FEE39_RS06755	COG1597	lipid kinase activity
FEE39_RS06760	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FEE39_RS06765	COG0154	amidase activity
FEE39_RS06770	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FEE39_RS06780	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
FEE39_RS06790	COG1705	Flagellar rod assembly protein muramidase FlgJ
FEE39_RS06795	COG4684	Psort location CytoplasmicMembrane, score
FEE39_RS06805	COG3091	SprT-like family
FEE39_RS06820	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
FEE39_RS06830	COG1132	(ABC) transporter
FEE39_RS06840	COG0464	growth
FEE39_RS06845	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
FEE39_RS06850	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
FEE39_RS06855	COG0463	Glycosyl transferase, family 2
FEE39_RS06855	COG1216	Glycosyl transferase, family 2
FEE39_RS06875	COG2188	Transcriptional regulator
FEE39_RS06910	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
FEE39_RS06915	COG0673	inositol 2-dehydrogenase activity
FEE39_RS06965	COG0656	L-ascorbic acid biosynthetic process
FEE39_RS06970	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FEE39_RS06985	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FEE39_RS06990	COG1111	helicase
FEE39_RS06990	COG1205	dead DEAH box helicase
FEE39_RS07015	COG3344	reverse transcriptase
FEE39_RS07025	COG1012	belongs to the aldehyde dehydrogenase family
FEE39_RS07025	COG1454	alcohol dehydrogenase
FEE39_RS07030	COG1113	amino acid transport
FEE39_RS07170	COG1368	sulfuric ester hydrolase activity
FEE39_RS07180	COG0438	transferase activity, transferring glycosyl groups
FEE39_RS07185	COG0438	transferase activity, transferring glycosyl groups
FEE39_RS07355	COG0438	transferase activity, transferring glycosyl groups
FEE39_RS07360	COG0438	transferase activity, transferring glycosyl groups
FEE39_RS07525	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
FEE39_RS07530	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FEE39_RS07555	COG1012	belongs to the aldehyde dehydrogenase family
FEE39_RS07570	COG0561	phosphatase activity
FEE39_RS07575	COG2409	Drug exporters of the RND superfamily
FEE39_RS07575	COG1033	growth of symbiont in host cell
FEE39_RS07580	COG1309	transcriptional regulator
FEE39_RS07590	COG2971	BadF BadG BcrA BcrD
FEE39_RS07605	COG1846	Transcriptional regulator
FEE39_RS07620	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
FEE39_RS07630	COG1175	transmembrane transport
FEE39_RS07635	COG3842	ATPase activity
FEE39_RS07660	COG2176	DNA-directed DNA polymerase activity
FEE39_RS07680	COG2195	Cleaves the N-terminal amino acid of tripeptides
FEE39_RS07700	COG1970	mechanosensitive ion channel activity
FEE39_RS07710	COG1823	symporter activity
FEE39_RS07715	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
FEE39_RS07720	COG1854	S-ribosylhomocysteine lyase activity
FEE39_RS07730	COG3716	PTS system mannose fructose sorbose family IID component
FEE39_RS07740	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
FEE39_RS07740	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FEE39_RS07765	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
FEE39_RS07770	COG1072	(Pantothenic acid kinase))
FEE39_RS07780	COG4990	cell redox homeostasis
FEE39_RS07785	COG3973	AAA domain
FEE39_RS07805	COG1737	Transcriptional regulator
FEE39_RS07810	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
FEE39_RS07815	COG1263	PTS System
FEE39_RS07815	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FEE39_RS07815	COG2190	(PTS) system
FEE39_RS07820	COG0708	Exodeoxyribonuclease III
FEE39_RS07835	COG0588	phosphoglycerate mutase activity
FEE39_RS07845	COG1136	(ABC) transporter
FEE39_RS07850	COG0531	amino acid
FEE39_RS07855	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
FEE39_RS07870	COG0194	GDP metabolic process
FEE39_RS07890	COG1780	Probably involved in ribonucleotide reductase function
FEE39_RS07920	COG2966	Psort location CytoplasmicMembrane, score
FEE39_RS07925	COG0488	(ABC) transporter
FEE39_RS07940	COG1316	TRANSCRIPTIONal
FEE39_RS07950	COG1620	l-lactate permease
FEE39_RS07955	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FEE39_RS07960	COG1121	(ABC) transporter
FEE39_RS07970	COG0640	Transcriptional regulator
FEE39_RS07975	COG0561	phosphatase activity
FEE39_RS07985	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FEE39_RS07985	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FEE39_RS07985	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FEE39_RS07990	COG1105	Belongs to the carbohydrate kinase PfkB family
FEE39_RS07995	COG1349	DNA-binding transcription factor activity
FEE39_RS08005	COG1668	transmembrane transport
FEE39_RS08010	COG4152	abc transporter atp-binding protein
FEE39_RS08015	COG1794	racemase activity, acting on amino acids and derivatives
FEE39_RS08020	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
FEE39_RS08025	COG5002	protein histidine kinase activity
FEE39_RS08035	COG1132	(ABC) transporter
FEE39_RS08040	COG1132	(ABC) transporter
FEE39_RS08050	COG0012	GTP binding
FEE39_RS08055	COG4481	Protein conserved in bacteria
FEE39_RS08060	COG1475	DNA binding
FEE39_RS08065	COG1192	Involved in chromosome partitioning
FEE39_RS08075	COG0357	Ribosomal RNA small subunit methyltransferase G
FEE39_RS08100	COG0431	NADPH-dependent FMN reductase
FEE39_RS08105	COG0431	NADPH-dependent FMN reductase
FEE39_RS08110	COG3344	reverse transcriptase
FEE39_RS08130	COG1136	(ABC) transporter
FEE39_RS08145	COG0588	phosphoglycerate mutase activity
FEE39_RS08150	COG0588	phosphoglycerate mutase activity
FEE39_RS08160	COG3022	response to hydroperoxide
FEE39_RS08195	COG3104	oligopeptide transport
FEE39_RS08215	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
FEE39_RS08225	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
FEE39_RS08230	COG1132	(ABC) transporter
FEE39_RS08235	COG3842	ATPase activity
FEE39_RS08240	COG2190	(PTS) system
FEE39_RS08240	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FEE39_RS08240	COG1263	PTS System
FEE39_RS08255	COG2365	Tyrosine phosphatase family
FEE39_RS08260	COG0351	phosphomethylpyrimidine kinase
FEE39_RS08265	COG3442	glutamine amidotransferase
FEE39_RS08270	COG0531	amino acid
FEE39_RS08280	COG2502	aspartate--ammonia ligase
FEE39_RS08290	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
FEE39_RS08300	COG1113	amino acid transport
FEE39_RS08305	COG1113	amino acid transport
FEE39_RS08315	COG3716	PTS system mannose fructose sorbose family IID component
FEE39_RS08320	COG3715	PTS system
FEE39_RS08455	COG0531	amino acid
FEE39_RS08460	COG0542	response to heat
FEE39_RS08480	COG2814	Major facilitator Superfamily
FEE39_RS08490	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
FEE39_RS08495	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FEE39_RS08500	COG1696	Membrane protein involved in D-alanine export
FEE39_RS08505	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FEE39_RS08545	COG0517	IMP dehydrogenase activity
FEE39_RS08565	COG1132	(ABC) transporter
FEE39_RS08575	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
FEE39_RS08605	COG3775	system Galactitol-specific IIC component
FEE39_RS08615	COG1266	CAAX protease self-immunity
FEE39_RS08625	COG0577	efflux transmembrane transporter activity
FEE39_RS08625	COG1136	(ABC) transporter
FEE39_RS08625	COG0577	efflux transmembrane transporter activity
FEE39_RS08625	COG1136	(ABC) transporter
FEE39_RS08630	COG1271	oxidase subunit
FEE39_RS08635	COG1294	oxidase, subunit
FEE39_RS08640	COG4988	ABC transporter
FEE39_RS08645	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
FEE39_RS08660	COG1744	ABC transporter substrate-binding protein PnrA-like
FEE39_RS08665	COG1737	Transcriptional regulator
FEE39_RS08675	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
FEE39_RS08680	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FEE39_RS08680	COG1263	PTS System
FEE39_RS08690	COG0656	L-ascorbic acid biosynthetic process
FEE39_RS08695	COG0363	glucosamine-6-phosphate deaminase activity
FEE39_RS08700	COG1428	Deoxynucleoside kinase
FEE39_RS08705	COG1428	Deoxynucleoside kinase
FEE39_RS08710	COG1304	FMN binding
FEE39_RS08715	COG2252	PERMEase
FEE39_RS08720	COG0789	Transcriptional regulator
FEE39_RS08725	COG2252	PERMEase
FEE39_RS08730	COG2252	PERMEase
FEE39_RS08740	COG0242	peptide deformylase activity
FEE39_RS08770	COG2217	Heavy metal translocating P-type atpase
FEE39_RS08775	COG0531	amino acid
FEE39_RS08785	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
FEE39_RS08795	COG0477	Major facilitator Superfamily
FEE39_RS08810	COG1193	negative regulation of DNA recombination
FEE39_RS08820	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
FEE39_RS08825	COG0028	Belongs to the TPP enzyme family
FEE39_RS08830	COG0445	tRNA wobble uridine modification
FEE39_RS08835	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
FEE39_RS08840	COG0706	membrane insertase activity
FEE39_RS08845	COG0594	ribonuclease P activity
FEE39_RS08855	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
FEE39_RS08860	COG0592	DNA-directed DNA polymerase activity
FEE39_RS08865	COG2501	S4 domain
FEE39_RS08870	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
FEE39_RS08875	COG0187	DNA topoisomerase II activity
FEE39_RS08880	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FEE39_RS08885	COG0360	Binds together with S18 to 16S ribosomal RNA
FEE39_RS08890	COG0629	single-stranded DNA binding
FEE39_RS08895	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
FEE39_RS08910	COG0359	binds to the 23S rRNA
FEE39_RS08915	COG0305	Participates in initiation and elongation during chromosome replication
FEE39_RS08920	COG1940	carbohydrate kinase activity
FEE39_RS08940	COG3344	reverse transcriptase
FEE39_RS08945	COG0531	amino acid
FEE39_RS08980	COG1011	Hydrolase
FEE39_RS08985	COG1307	EDD domain protein, DegV family
FEE39_RS08995	COG1132	(ABC) transporter
FEE39_RS09015	COG3590	peptidase
FEE39_RS09040	COG2261	transglycosylase associated protein
FEE39_RS09045	COG0708	Exodeoxyribonuclease III
FEE39_RS09065	COG0628	permease
FEE39_RS09070	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FEE39_RS09075	COG0516	GMP reductase activity
FEE39_RS09075	COG0517	IMP dehydrogenase activity
FEE39_RS09085	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FEE39_RS09110	COG3344	reverse transcriptase
FEE39_RS09115	COG0531	amino acid
FEE39_RS09125	COG3976	FMN-binding domain protein
FEE39_RS09125	COG1053	succinate dehydrogenase
FEE39_RS09130	COG1114	Component of the transport system for branched-chain amino acids
FEE39_RS09135	COG2226	methyltransferase
FEE39_RS09140	COG2267	carboxylic ester hydrolase activity
FEE39_RS09170	COG1442	glycosyl transferase family 8
FEE39_RS09205	COG0745	RESPONSE REGULATOR receiver
FEE39_RS09210	COG5002	protein histidine kinase activity
FEE39_RS09225	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
FEE39_RS09230	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FEE39_RS09235	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
FEE39_RS09245	COG1122	ATPase activity
FEE39_RS09260	COG0501	Belongs to the peptidase M48B family
FEE39_RS09265	COG1704	LemA family
FEE39_RS09270	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
FEE39_RS09330	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
FEE39_RS09340	COG3549	Plasmid maintenance system killer
FEE39_RS09410	COG3549	Plasmid maintenance system killer
FEE39_RS09420	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
FEE39_RS09525	COG0270	DNA (cytosine-5-)-methyltransferase activity
FEE39_RS09565	COG0675	Transposase, IS605 OrfB family
FEE39_RS09650	COG0542	response to heat
FEE39_RS09795	COG0776	regulation of translation
FEE39_RS09815	COG2226	methyltransferase
FEE39_RS09825	COG0675	Transposase, IS605 OrfB family
FEE39_RS09870	COG3513	CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
FEE39_RS09960	COG2161	toxin-antitoxin pair type II binding
FEE39_RS09985	COG2161	toxin-antitoxin pair type II binding
FEE39_RS10105	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
FEE39_RS10110	COG3177	Filamentation induced by cAMP protein fic
FEE39_RS10175	COG0270	DNA (cytosine-5-)-methyltransferase activity
FEE39_RS10370	COG3513	CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
FEE39_RS10485	COG1396	sequence-specific DNA binding
FEE39_RS10515	COG0629	single-stranded DNA binding
FEE39_RS10605	COG1192	Involved in chromosome partitioning