locus-tag	class	description
H0I41_RS00005	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
H0I41_RS00010	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
H0I41_RS00015	ENOG410848D	S4 domain protein YaaA
H0I41_RS00020	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
H0I41_RS00025	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
H0I41_RS00030	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
H0I41_RS00035	ENOG4108ZDX	Binds together with S18 to 16S ribosomal RNA (By similarity)
H0I41_RS00040	ENOG4108UUM	single-stranded DNA-binding protein
H0I41_RS00045	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
H0I41_RS00060	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
H0I41_RS00065	ENOG4105CDU	Replicative dna helicase
H0I41_RS00070	ENOG4105EVU	fructokinase
H0I41_RS00135	ENOG4107R7I	amino acid
H0I41_RS00170	ENOG4105D06	uba thif-type nad fad binding protein
H0I41_RS00190	ENOG4108S8M	degv family
H0I41_RS00220	ENOG4105C9K	Endothelin-converting enzyme 1
H0I41_RS00245	ENOG4107BMA	Transglycosylase associated protein
H0I41_RS00250	ENOG4105CGK	Exodeoxyribonuclease III
H0I41_RS00280	ENOG4106F5Q	Membrane
H0I41_RS00290	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
H0I41_RS00300	ENOG4105C5I	Dehydrogenase
H0I41_RS00320	ENOG4105E5D	amino acid
H0I41_RS00325	ENOG4105C5Q	Transcriptional regulator
H0I41_RS00335	ENOG4105CWM	branched-chain amino acid transport system II carrier protein
H0I41_RS00340	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
H0I41_RS00345	ENOG4107T66	Releases the N-terminal proline from various substrates (By similarity)
H0I41_RS00410	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
H0I41_RS00415	ENOG4105BZU	Histidine kinase
H0I41_RS00430	ENOG4105Q2H	domain protein
H0I41_RS00435	ENOG4105C0H	protease
H0I41_RS00440	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
H0I41_RS00450	ENOG4108JJB	ABC transporter
H0I41_RS00465	ENOG4105D0M	Protease HtpX homolog
H0I41_RS00470	ENOG4108V0P	LemA family
H0I41_RS00475	ENOG4105F4P	)-transporter
H0I41_RS00500	ENOG4107R8N	Glycosyl transferase, family 2
H0I41_RS00505	ENOG4105K2Z	endo-1,4-d-glucanase (EC 3.2.1.4)
H0I41_RS00525	ENOG4105CDA	abc transporter atp-binding protein
H0I41_RS00530	ENOG4105E5Q	amino acid AbC transporter
H0I41_RS00535	ENOG4108VX5	3-methyladenine DNA glycosylase
H0I41_RS00540	ENOG4105K78	MarR family Transcriptional regulator
H0I41_RS00545	ENOG4107TS3	membrane protein, TerC
H0I41_RS00550	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
H0I41_RS00555	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
H0I41_RS00565	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
H0I41_RS00580	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
H0I41_RS00595	ENOG4105K64	Glycosyl transferase, family 2
H0I41_RS00610	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
H0I41_RS00615	ENOG4105C85	amino acid
H0I41_RS00635	ENOG4105CPF	Cell wall formation (By similarity)
H0I41_RS00645	ENOG4105EEQ	Na H antiporter
H0I41_RS00675	ENOG4105E70	isomerase
H0I41_RS00680	ENOG4105CE4	GlcNAc 6-P deacetylase
H0I41_RS00685	ENOG4108IQ3	PTS system
H0I41_RS00690	ENOG4105ETZ	PTS System
H0I41_RS00695	ENOG4105F3R	pts system mannose fructose sorbose family iid
H0I41_RS00700	ENOG4105DAS	pts system
H0I41_RS00710	ENOG4106D5D	Nucleoside deoxyribosyltransferase
H0I41_RS00720	ENOG4105FDP	GntR family transcriptional regulator
H0I41_RS00725	ENOG4105M2Z	protein tyrosine serine phosphatase
H0I41_RS00730	ENOG4107YZX	Universal stress protein
H0I41_RS00745	ENOG4105D5T	phosphonate abc transporter
H0I41_RS00770	ENOG4105CAQ	asparagine synthetase
H0I41_RS00780	ENOG4105CJD	(Anaerobic) ribonucleoside-triphosphate reductase
H0I41_RS00785	ENOG4108RDD	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine (By similarity)
H0I41_RS00790	ENOG4105VG1	fes assembly suf system protein
H0I41_RS00800	ENOG410605W	Major Facilitator
H0I41_RS00805	ENOG4105D2M	Aldolase
H0I41_RS00820	ENOG4105DE4	1-phosphofructokinase
H0I41_RS00825	ENOG4105DM4	PTS System
H0I41_RS00830	ENOG4105C9K	Endothelin-converting enzyme 1
H0I41_RS00840	ENOG4105DJ1	Phosphoenolpyruvate Carboxylase
H0I41_RS00845	ENOG4105DFH	Transport of potassium into the cell (By similarity)
H0I41_RS00850	ENOG4105DFH	Transport of potassium into the cell (By similarity)
H0I41_RS00895	ENOG4105EE0	oxidoreductase
H0I41_RS00915	ENOG4105DKJ	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
H0I41_RS00920	ENOG4105PF0	Antitoxin component of a toxin-antitoxin (TA) module. Functions as an mRNA interferase antitoxin
H0I41_RS00925	ENOG41082QR	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
H0I41_RS00935	ENOG4105CKK	Glycosyl transferase, family 2
H0I41_RS00945	ENOG4105CSC	Glucose uptake protein
H0I41_RS00955	ENOG4108KGH	TRANSCRIPTIONal
H0I41_RS00960	ENOG4108Y1J	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
H0I41_RS00965	ENOG4107UZV	polysaccharide biosynthesis
H0I41_RS00970	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
H0I41_RS00980	ENOG4105CTZ	aminopeptidase c
H0I41_RS00990	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
H0I41_RS00995	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
H0I41_RS01005	ENOG4108JQ7	(ABC) transporter
H0I41_RS01025	ENOG4105KP9	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
H0I41_RS01035	ENOG4105CS2	ec 3.2.1.21
H0I41_RS01045	ENOG4105CK1	PTS System
H0I41_RS01050	ENOG4108S3Y	transcriptional regulator
H0I41_RS01060	ENOG4105CS2	ec 3.2.1.21
H0I41_RS01065	ENOG4108TZY	GntR Family Transcriptional Regulator
H0I41_RS01070	ENOG4105VCP	PTS System
H0I41_RS01080	ENOG4105VZJ	PTS System
H0I41_RS01090	ENOG4105CS2	ec 3.2.1.21
H0I41_RS01095	ENOG41066F8	ROK family
H0I41_RS01120	ENOG4108UK2	deaminase
H0I41_RS01130	ENOG4105C52	Atpase, p-type (Transporting), had superfamily, subfamily ic
H0I41_RS01135	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
H0I41_RS01140	ENOG4105F8V	Hydrolase, tatD family
H0I41_RS01150	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
H0I41_RS01155	ENOG4105W42	Veg protein
H0I41_RS01160	ENOG4105DFT	pur operon repressor
H0I41_RS01165	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
H0I41_RS01170	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
H0I41_RS01175	ENOG4105FKQ	transcriptional regulator
H0I41_RS01180	ENOG4105CG3	alpha amylase, catalytic region
H0I41_RS01185	ENOG4108IUK	alpha amylase, catalytic
H0I41_RS01195	ENOG4107URF	beta-phospho-glucomutase
H0I41_RS01200	ENOG4108IJ9	(ABC) transporter
H0I41_RS01205	ENOG4105XN3	extracellular solute-binding protein family 1
H0I41_RS01210	ENOG4105D56	permease protein
H0I41_RS01215	ENOG4105EG2	ABC transporter, permease
H0I41_RS01220	ENOG4105CG3	alpha amylase, catalytic region
H0I41_RS01225	ENOG4105DCI	Phosphohydrolase
H0I41_RS01235	ENOG4108Z1Y	Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling (By similarity)
H0I41_RS01240	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
H0I41_RS01245	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
H0I41_RS01255	ENOG4108UPS	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis (By similarity)
H0I41_RS01265	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
H0I41_RS01270	ENOG4105KVH	Transcriptional regulator
H0I41_RS01290	ENOG4105KIS	phospholipid-binding protein
H0I41_RS01300	ENOG4108IMY	Transcriptional regulator
H0I41_RS01305	ENOG4105DYS	nad(p)h dehydrogenase (quinone)
H0I41_RS01365	ENOG4108R6G	acetyltransferase
H0I41_RS01380	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
H0I41_RS01385	ENOG4105CFN	oxalyl-CoA decarboxylase
H0I41_RS01390	ENOG4108N2Y	auxin Efflux
H0I41_RS01410	ENOG4105KVH	Transcriptional regulator
H0I41_RS01420	ENOG4108DBC	nitroreductase
H0I41_RS01425	ENOG4105DZW	Dipeptidase
H0I41_RS01430	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
H0I41_RS01440	ENOG4105C7J	ABC transporter, permease
H0I41_RS01450	ENOG4107QTZ	amino acid
H0I41_RS01455	ENOG41082DI	50s ribosomal protein l31
H0I41_RS01460	ENOG4107EES	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide the precursor of murein (By similarity)
H0I41_RS01465	ENOG4105C1J	atp-dependent rna helicase
H0I41_RS01470	ENOG41082V8	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (By similarity)
H0I41_RS01475	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
H0I41_RS01485	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
H0I41_RS01490	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
H0I41_RS01495	ENOG4108JA2	transcriptioN-repair coupling factor
H0I41_RS01500	ENOG41082I2	s4 domain protein
H0I41_RS01510	ENOG4107QUF	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
H0I41_RS01515	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
H0I41_RS01535	ENOG4105F4C	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity)
H0I41_RS01540	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
H0I41_RS01545	ENOG4105CRK	lysyL-tRNA synthetase
H0I41_RS01560	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
H0I41_RS01565	ENOG4108IIJ	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
H0I41_RS01570	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
H0I41_RS01580	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
H0I41_RS01585	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
H0I41_RS01590	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
H0I41_RS01595	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
H0I41_RS01600	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
H0I41_RS01605	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
H0I41_RS01610	ENOG41080UE	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
H0I41_RS01615	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
H0I41_RS01620	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
H0I41_RS01625	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
H0I41_RS01630	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
H0I41_RS01635	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
H0I41_RS01640	ENOG41082SA	50s ribosomal protein l29
H0I41_RS01645	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
H0I41_RS01650	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
H0I41_RS01655	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
H0I41_RS01660	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
H0I41_RS01670	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
H0I41_RS01675	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
H0I41_RS01680	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
H0I41_RS01685	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
H0I41_RS01690	ENOG4105VPB	50S ribosomal protein L30
H0I41_RS01695	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
H0I41_RS01700	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
H0I41_RS01705	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
H0I41_RS01710	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
H0I41_RS01715	ENOG41067V7	50S ribosomal protein L36
H0I41_RS01720	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
H0I41_RS01725	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
H0I41_RS01730	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
H0I41_RS01735	ENOG4108ZT0	50S ribosomal protein l17
H0I41_RS01740	ENOG4108JJB	ABC transporter
H0I41_RS01745	ENOG4108JJB	ABC transporter
H0I41_RS01750	ENOG4105EK6	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates (By similarity)
H0I41_RS01755	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
H0I41_RS01760	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
H0I41_RS01765	ENOG4108UJD	30S ribosomal protein S9
H0I41_RS01775	ENOG4105BZ1	(ABC) transporter
H0I41_RS01805	ENOG4105PGM	cation diffusion facilitator family transporter
H0I41_RS01820	ENOG4108K79	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
H0I41_RS01840	ENOG4105E5D	amino acid
H0I41_RS01855	ENOG41089G2	accessory Sec system protein Asp2
H0I41_RS01865	ENOG4108MGR	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane (By similarity)
H0I41_RS01895	ENOG4105GH9	galactofuranosyltransferase
H0I41_RS01900	ENOG4105CTZ	aminopeptidase c
H0I41_RS01905	ENOG4108KGH	TRANSCRIPTIONal
H0I41_RS01910	ENOG4107Z0P	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity)
H0I41_RS01920	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
H0I41_RS01925	ENOG4105C8N	cysteinyl-tRNA synthetase
H0I41_RS01930	ENOG4105KEB	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
H0I41_RS01935	ENOG4105C2N	RNA methyltransferase TrmH family group 3
H0I41_RS01950	ENOG4105CMG	Carbohydrate kinase
H0I41_RS01955	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
H0I41_RS01965	ENOG4105EAH	synthase
H0I41_RS01970	ENOG4107FTN	50S ribosomal protein L33
H0I41_RS01980	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
H0I41_RS01985	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
H0I41_RS01990	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
H0I41_RS01995	ENOG4105E5Q	amino acid AbC transporter
H0I41_RS02000	ENOG4105CDA	abc transporter atp-binding protein
H0I41_RS02005	ENOG4106TNF	Periplasmic binding protein
H0I41_RS02010	ENOG4108VZM	50s ribosomal protein L10
H0I41_RS02015	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
H0I41_RS02030	ENOG4107Y49	methyltransferase
H0I41_RS02050	ENOG4108Z6B	deaminase
H0I41_RS02060	ENOG4105C6E	dna polymerase iii
H0I41_RS02065	ENOG410816I	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
H0I41_RS02070	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
H0I41_RS02080	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
H0I41_RS02085	ENOG4105X0R	protein from nitrogen regulatory protein P-II
H0I41_RS02095	ENOG4105QD5	Involved in initiation control of chromosome replication (By similarity)
H0I41_RS02110	ENOG4105X71	Membrane
H0I41_RS02115	ENOG41072GX	Peptidase M22 Glycoprotease
H0I41_RS02125	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
H0I41_RS02150	ENOG4107SJ1	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides (By similarity)
H0I41_RS02155	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
H0I41_RS02160	ENOG4105C83	adenylosuccinate lyase
H0I41_RS02170	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
H0I41_RS02215	ENOG4107YY3	extracellular solute-binding protein family 1
H0I41_RS02220	ENOG4105C5H	ABC transporter
H0I41_RS02230	ENOG4105FF6	Modulates transcription in response to changes in cellular NADH NAD( ) redox state (By similarity)
H0I41_RS02235	ENOG4108URH	decarboxylase
H0I41_RS02260	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
H0I41_RS02265	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
H0I41_RS02295	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
H0I41_RS02300	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
H0I41_RS02305	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
H0I41_RS02310	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
H0I41_RS02315	ENOG4105VIE	preprotein translocase, subunit YajC
H0I41_RS02320	ENOG4105D8W	glucose-6-phosphate 1-dehydrogenase
H0I41_RS02325	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
H0I41_RS02330	ENOG4105SFS	phosphoesterase RecJ domain protein
H0I41_RS02335	ENOG4105C1J	atp-dependent rna helicase
H0I41_RS02340	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
H0I41_RS02345	ENOG4105VBH	UPF0297 protein
H0I41_RS02350	ENOG4108Z08	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
H0I41_RS02355	ENOG4105VPH	UPF0473 protein
H0I41_RS02365	ENOG4105C98	muts2 protein
H0I41_RS02370	ENOG4105K63	Thioredoxin
H0I41_RS02380	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
H0I41_RS02385	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
H0I41_RS02395	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
H0I41_RS02400	ENOG4105D8X	mechanosensitive ion channel
H0I41_RS02415	ENOG4105DC7	peptidase M24
H0I41_RS02435	ENOG4108QXE	glycerophosphoryl diester phosphodiesterase
H0I41_RS02445	ENOG4107R8B	5'-nucleotidase
H0I41_RS02455	ENOG4105D4U	had-superfamily hydrolase, subfamily iia
H0I41_RS02465	ENOG4105DQR	SNARE associated Golgi
H0I41_RS02470	ENOG4105CAY	ferredoxin--nadp reductase
H0I41_RS02515	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
H0I41_RS02520	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
H0I41_RS02535	ENOG4105C8T	Leucyl-tRNA synthetase
H0I41_RS02555	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
H0I41_RS02565	ENOG4105C75	arginyL-tRNA synthetase
H0I41_RS02570	ENOG4105D2N	Aldolase
H0I41_RS02580	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
H0I41_RS02595	ENOG4105ETZ	PTS System
H0I41_RS02600	ENOG4105F3R	pts system mannose fructose sorbose family iid
H0I41_RS02605	ENOG4105KT7	mgtC SapB transporter
H0I41_RS02610	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
H0I41_RS02615	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
H0I41_RS02645	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
H0I41_RS02660	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
H0I41_RS02695	ENOG4108HCJ	Hydrolase
H0I41_RS02705	ENOG410667J	hydrolase
H0I41_RS02710	ENOG4107S4Z	Activates expression of the rhaBAD and rhaT operons (By similarity)
H0I41_RS02720	ENOG4105E98	transcriptional regulator DeoR family
H0I41_RS02725	ENOG4105RSI	Galactose-6-phosphate isomerase subunit LacA
H0I41_RS02730	ENOG4108YZG	isomerase
H0I41_RS02740	ENOG4105VCP	PTS System
H0I41_RS02745	ENOG4105CK1	PTS System
H0I41_RS02750	ENOG4105CS2	ec 3.2.1.21
H0I41_RS02775	ENOG4105E5D	amino acid
H0I41_RS02780	ENOG4105DZW	Dipeptidase
H0I41_RS02785	ENOG4105CTZ	aminopeptidase c
H0I41_RS02790	ENOG4105E5D	amino acid
H0I41_RS02810	ENOG4105C6X	Major Facilitator
H0I41_RS02840	ENOG41083J0	(ABC) transporter
H0I41_RS02845	ENOG4105C4B	ABC transporter, permease
H0I41_RS02865	ENOG4105DUX	Transporter
H0I41_RS02870	ENOG4105DZW	Dipeptidase
H0I41_RS02875	ENOG4107RGD	Major Facilitator superfamily
H0I41_RS02890	ENOG4105BZ1	(ABC) transporter
H0I41_RS02895	ENOG4105BZ1	(ABC) transporter
H0I41_RS02900	ENOG4105CT1	(ABC) transporter
H0I41_RS02910	ENOG4105CT1	(ABC) transporter
H0I41_RS02915	ENOG4105EAD	ABC transporter
H0I41_RS02920	ENOG4105DRP	amino acid AbC transporter
H0I41_RS02930	ENOG4105CG3	alpha amylase, catalytic region
H0I41_RS02935	ENOG4107414	GntR family transcriptional regulator
H0I41_RS02940	ENOG4105C5Y	PTS System
H0I41_RS02955	ENOG4105DBI	uridine monophosphokinase
H0I41_RS02975	ENOG4105D7V	transposase
H0I41_RS02985	ENOG4108JJA	ABC, transporter
H0I41_RS03070	ENOG4105E5Q	amino acid AbC transporter
H0I41_RS03075	ENOG4105CDA	abc transporter atp-binding protein
H0I41_RS03090	ENOG4105C8U	phosphate abc transporter
H0I41_RS03095	ENOG4105E2Z	phosphate ABC transporter (Permease
H0I41_RS03100	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
H0I41_RS03105	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
H0I41_RS03110	ENOG4108UTW	Plays a role in the regulation of phosphate uptake
H0I41_RS03115	ENOG4105CSX	c4-dicarboxylate anaerobic carrier
H0I41_RS03120	ENOG4105HUF	DNA protection during starvation protein
H0I41_RS03130	ENOG4105E66	phosphoriboisomerase A
H0I41_RS03140	ENOG4108TZY	GntR Family Transcriptional Regulator
H0I41_RS03170	ENOG4105C37	(CBS) domain
H0I41_RS03175	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
H0I41_RS03180	ENOG4107R7I	amino acid
H0I41_RS03195	ENOG4105CK1	PTS System
H0I41_RS03205	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
H0I41_RS03215	ENOG4105NQC	Flavodoxin
H0I41_RS03220	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
H0I41_RS03230	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
H0I41_RS03235	ENOG4108IJ8	ABC transporter
H0I41_RS03260	ENOG4105ETX	regulatoR
H0I41_RS03265	ENOG4105US7	Histidine kinase
H0I41_RS03270	ENOG4105GYP	Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline (By similarity)
H0I41_RS03275	ENOG4105CD8	aminopeptidase N
H0I41_RS03280	ENOG4108K4B	hydrolase
H0I41_RS03290	ENOG4105BZ1	(ABC) transporter
H0I41_RS03295	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
H0I41_RS03330	ENOG4108HIY	periplasmic
H0I41_RS03340	ENOG4105CTZ	aminopeptidase c
H0I41_RS03380	ENOG4105WV0	Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49)
H0I41_RS03400	ENOG41069HH	4-oxalocrotonate tautomerase
H0I41_RS03420	ENOG41080E8	Transcriptional regulator, Spx MgsR family
H0I41_RS03425	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
H0I41_RS03430	ENOG4105K46	50S ribosomal protein l27
H0I41_RS03435	ENOG4105DC7	peptidase M24
H0I41_RS03440	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
H0I41_RS03450	ENOG4105M7K	Involved in the transcription termination process (By similarity)
H0I41_RS03455	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
H0I41_RS03460	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
H0I41_RS03465	ENOG41067QG	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
H0I41_RS03475	ENOG4105DX0	Hemolysin A
H0I41_RS03480	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
H0I41_RS03490	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
H0I41_RS03495	ENOG4105ZAD	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
H0I41_RS03500	ENOG4105C25	Primosomal protein n'
H0I41_RS03505	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
H0I41_RS03510	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
H0I41_RS03515	ENOG4108ZF3	Phosphatase
H0I41_RS03520	ENOG4105D9P	serine threonine protein kinase
H0I41_RS03525	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
H0I41_RS03530	ENOG4105DJV	ribulose-phosphate 3-epimerase
H0I41_RS03535	ENOG4105FJ0	thiamine
H0I41_RS03540	ENOG4105VB9	50S ribosomal protein l28
H0I41_RS03550	ENOG4105DP4	dak2 domain fusion protein ylov
H0I41_RS03555	ENOG4105CB5	ATP-dependent DNA helicase recG
H0I41_RS03560	ENOG4105C6B	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (By similarity)
H0I41_RS03565	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
H0I41_RS03575	ENOG4108JQ7	(ABC) transporter
H0I41_RS03580	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
H0I41_RS03585	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
H0I41_RS03600	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
H0I41_RS03605	ENOG4105CDB	Required for chromosome condensation and partitioning (By similarity)
H0I41_RS03610	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
H0I41_RS03615	ENOG4105DZW	Dipeptidase
H0I41_RS03625	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
H0I41_RS03630	ENOG4105K5M	30s ribosomal protein S16
H0I41_RS03635	ENOG4107Z8R	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
H0I41_RS03640	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
H0I41_RS03645	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
H0I41_RS03655	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
H0I41_RS03665	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
H0I41_RS03670	ENOG41086B1	Bacterial protein of unknown function (DUF896)
H0I41_RS03675	ENOG4105VXM	UPF0154 protein
H0I41_RS03680	ENOG4105BZ1	(ABC) transporter
H0I41_RS03685	ENOG4105BZ1	(ABC) transporter
H0I41_RS03695	ENOG4105F6E	Acyl-transferase
H0I41_RS03700	ENOG41060K3	Methyltransferase
H0I41_RS03705	ENOG4105CE9	30S ribosomal protein S2
H0I41_RS03710	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
H0I41_RS03715	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
H0I41_RS03720	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
H0I41_RS03725	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
H0I41_RS03730	ENOG4105KNE	Phosphatidate cytidylyltransferase
H0I41_RS03735	ENOG4105DZP	Membrane-associated zinc metalloprotease
H0I41_RS03740	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
H0I41_RS03750	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
H0I41_RS03755	ENOG4105CHV	Transcription elongation factor NusA
H0I41_RS03760	ENOG4105VZN	Nucleic-acid-binding protein implicated in transcription termination
H0I41_RS03770	ENOG4107EEM	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
H0I41_RS03775	ENOG4105KG7	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
H0I41_RS03780	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
H0I41_RS03785	ENOG4105DTN	riboflavin biosynthesis protein ribF
H0I41_RS03790	ENOG4105C5H	ABC transporter
H0I41_RS03800	ENOG4105CI8	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons (By similarity)
H0I41_RS03805	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
H0I41_RS03810	ENOG4105CFG	Acts as a chaperone (By similarity)
H0I41_RS03815	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
H0I41_RS03820	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
H0I41_RS03825	ENOG4108Z6X	(sortase) family
H0I41_RS03830	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
H0I41_RS03835	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
H0I41_RS03840	ENOG4107SC7	Inner membrane transporter yjeM
H0I41_RS03845	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
H0I41_RS03850	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
H0I41_RS03855	ENOG4108YYV	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity)
H0I41_RS03865	ENOG4105C59	p-type ATPase
H0I41_RS03870	ENOG4106P55	Transcriptional regulator
H0I41_RS03895	ENOG4105C5H	ABC transporter
H0I41_RS03900	ENOG4107QHE	Choloylglycine hydrolase
H0I41_RS03920	ENOG4105D01	(LipO)protein
H0I41_RS03925	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
H0I41_RS03930	ENOG4108UMI	ABC transporter, permease
H0I41_RS03935	ENOG4105C9Q	fumarate hydratase class II
H0I41_RS03940	ENOG4107EFR	Flavocytochrome c
H0I41_RS03945	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
H0I41_RS03955	ENOG4105HDK	L-asparaginase
H0I41_RS03960	ENOG4105C52	Atpase, p-type (Transporting), had superfamily, subfamily ic
H0I41_RS03970	ENOG4108Z66	YbaK ebsC protein
H0I41_RS03975	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
H0I41_RS03985	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
H0I41_RS03990	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
H0I41_RS03995	ENOG4105CUT	histidyl-tRNA synthetase
H0I41_RS04000	ENOG4105C9M	aspartyl-trna synthetase
H0I41_RS04005	ENOG4105CHM	Aminotransferase
H0I41_RS04010	ENOG4105E0X	reductase
H0I41_RS04030	ENOG4107AYK	membrAne
H0I41_RS04040	ENOG4105EJQ	L-serine dehydratase
H0I41_RS04045	ENOG4105VG1	fes assembly suf system protein
H0I41_RS04050	ENOG4105CF9	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation (By similarity)
H0I41_RS04055	ENOG4105VCC	30S ribosomal protein S21
H0I41_RS04060	ENOG4105KTH	gatB Yqey
H0I41_RS04065	ENOG4105C9A	Phoh family
H0I41_RS04070	ENOG4105KGE	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
H0I41_RS04075	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
H0I41_RS04080	ENOG4108SAY	Involved in DNA repair and RecF pathway recombination (By similarity)
H0I41_RS04085	ENOG4108HMW	glycyl-tRNA synthetase, alpha subunit
H0I41_RS04090	ENOG4105C38	Glycyl-tRNA synthetase beta subunit
H0I41_RS04095	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
H0I41_RS04100	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
H0I41_RS04140	ENOG4105E5Q	amino acid AbC transporter
H0I41_RS04145	ENOG4108HW4	amino acid AbC transporter
H0I41_RS04150	ENOG4105CDA	abc transporter atp-binding protein
H0I41_RS04165	ENOG4105EGD	dinuclear metal center protein, YbgI family
H0I41_RS04170	ENOG4105D42	Cleaves the N-terminal amino acid of tripeptides (By similarity)
H0I41_RS04175	ENOG4105W8V	TRANSCRIPTIONAl REGULATOR GntR family
H0I41_RS04180	ENOG4105CZV	ABC transporter
H0I41_RS04210	ENOG4105BZ1	(ABC) transporter
H0I41_RS04255	ENOG4105K8R	UPF0145 protein
H0I41_RS04260	ENOG4107S90	membrAne
H0I41_RS04275	ENOG41065E1	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
H0I41_RS04280	ENOG4106EG9	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity)
H0I41_RS04285	ENOG4107RY0	Catalyzes the conversion of dihydroorotate to orotate (By similarity)
H0I41_RS04290	ENOG4108UK1	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant (By similarity)
H0I41_RS04295	ENOG4105CXT	aspartate transcarbamylase
H0I41_RS04300	ENOG4105CD3	dihydroorotase
H0I41_RS04305	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
H0I41_RS04310	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
H0I41_RS04315	ENOG4108UK1	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant (By similarity)
H0I41_RS04325	ENOG4105CCA	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle (By similarity)
H0I41_RS04350	ENOG4105C9K	Endothelin-converting enzyme 1
H0I41_RS04355	ENOG4108JQ0	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
H0I41_RS04360	ENOG4108IUS	Transketolase
H0I41_RS04365	ENOG4108HHA	Transketolase
H0I41_RS04370	ENOG4105ETE	Transcriptional regulator (LacI family
H0I41_RS04385	ENOG4105CID	antiterminator
H0I41_RS04390	ENOG4105C5Y	PTS System
H0I41_RS04410	ENOG4108TVJ	Nitroreductase
H0I41_RS04415	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
H0I41_RS04430	ENOG4105BZW	Glycerate kinase
H0I41_RS04445	ENOG4108JJA	ABC, transporter
H0I41_RS04450	ENOG4105BZ1	(ABC) transporter
H0I41_RS04510	ENOG4105M2Z	protein tyrosine serine phosphatase
H0I41_RS04585	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
H0I41_RS04590	ENOG4105MRB	Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose (By similarity)
H0I41_RS04595	ENOG4105EV1	Ribose uptake protein RbsU
H0I41_RS04610	ENOG4108JJ9	ABC, transporter
H0I41_RS04615	ENOG4105BZ1	(ABC) transporter
H0I41_RS04635	ENOG4105CRD	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity)
H0I41_RS04640	ENOG4105C5N	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
H0I41_RS04645	ENOG4107R2I	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation
H0I41_RS04650	ENOG4105DVT	helicase
H0I41_RS04660	ENOG4105C5S	asparaginyl-tRNA synthetase
H0I41_RS04670	ENOG4105CSM	endonuclease III
H0I41_RS04680	ENOG4108UI2	Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation (By similarity)
H0I41_RS04685	ENOG4108UKS	UPF0398 protein
H0I41_RS04690	ENOG4105XWG	Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation (By similarity)
H0I41_RS04700	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
H0I41_RS04715	ENOG4105EPR	degv family
H0I41_RS04725	ENOG4105CKU	formyltetrahydrofolate synthetase
H0I41_RS04730	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
H0I41_RS04735	ENOG4105C34	Pseudouridine synthase
H0I41_RS04760	ENOG4105EPR	degv family
H0I41_RS04770	ENOG4108KB2	LysR family Transcriptional regulator
H0I41_RS04790	ENOG4105C9U	ATP-dependent DNA helicase RecQ
H0I41_RS04795	ENOG4105E2M	Manganese-dependent inorganic pyrophosphatase
H0I41_RS04810	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
H0I41_RS04815	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
H0I41_RS04820	ENOG4108UW5	maltose o-acetyltransferase
H0I41_RS04825	ENOG4105CV8	reductase
H0I41_RS04845	ENOG4105D1H	recombination factor protein RarA
H0I41_RS04855	ENOG4105CV8	reductase
H0I41_RS04860	ENOG4105BZ1	(ABC) transporter
H0I41_RS04870	ENOG4105C52	Atpase, p-type (Transporting), had superfamily, subfamily ic
H0I41_RS04880	ENOG4108V1J	Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity)
H0I41_RS04900	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
H0I41_RS04915	ENOG4107QHE	Choloylglycine hydrolase
H0I41_RS04935	ENOG4105C56	H( )-stimulated, divalent metal cation uptake system (By similarity)
H0I41_RS04945	ENOG4105DIW	FeS assembly protein SUFB
H0I41_RS04950	ENOG4108UNV	SUF system FeS assembly protein, NifU family
H0I41_RS04960	ENOG4105JRK	feS assembly protein SufD
H0I41_RS04965	ENOG4105C3K	feS assembly ATPase SufC
H0I41_RS04970	ENOG4105CWM	branched-chain amino acid transport system II carrier protein
H0I41_RS04990	ENOG4105GR3	Histidine kinase
H0I41_RS04995	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
H0I41_RS05035	ENOG4107FQX	Alpha-acetolactate decarboxylase
H0I41_RS05055	ENOG4105HMI	Membrane
H0I41_RS05080	ENOG4105C4N	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity)
H0I41_RS05095	ENOG4107QXI	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs (By similarity)
H0I41_RS05100	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
H0I41_RS05105	ENOG4105C79	DNA protecting protein DprA
H0I41_RS05110	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
H0I41_RS05115	ENOG4105C9W	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity (By similarity)
H0I41_RS05125	ENOG4105VSD	UPF0346 protein
H0I41_RS05130	ENOG4108RCR	degv family
H0I41_RS05135	ENOG4108UT2	hemolysin iii
H0I41_RS05140	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
H0I41_RS05145	ENOG4108JYZ	YitT family
H0I41_RS05155	ENOG4106H3A	restriction
H0I41_RS05200	ENOG4105K70	DNA-binding protein
H0I41_RS05205	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
H0I41_RS05210	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
H0I41_RS05215	ENOG4105CAT	Cytidine monophosphate kinase
H0I41_RS05220	ENOG4108SAX	Membrane
H0I41_RS05230	ENOG4105FE9	pseudouridine synthase
H0I41_RS05235	ENOG4105K8I	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity)
H0I41_RS05240	ENOG4108KVX	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves (By similarity)
H0I41_RS05255	ENOG4105QNR	S1 RNA binding domain protein
H0I41_RS05260	ENOG4105CA9	Pyruvate kinase
H0I41_RS05265	ENOG4105CTQ	phosphohexokinase
H0I41_RS05270	ENOG4105C0B	DNA polymerase III (alpha subunit)
H0I41_RS05280	ENOG4107RNS	bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase 3'-nucleotidase periplasmic
H0I41_RS05285	ENOG41086FC	50S ribosomal protein l32
H0I41_RS05295	ENOG4108IXY	short-chain dehydrogenase reductase
H0I41_RS05300	ENOG4105IES	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
H0I41_RS05305	ENOG4105EXC	Acyl-transferase
H0I41_RS05310	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
H0I41_RS05315	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
H0I41_RS05320	ENOG4105DU0	nucleoside hydrolase
H0I41_RS05325	ENOG4107T5V	SNARE associated Golgi
H0I41_RS05415	ENOG4105CS2	ec 3.2.1.21
H0I41_RS05425	ENOG4105CK1	PTS System
H0I41_RS05455	ENOG4105DBZ	Dtdp-4-dehydrorhamnose reductase
H0I41_RS05460	ENOG4108URP	Dtdp-4-dehydrorhamnose 3,5-epimerase
H0I41_RS05470	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
H0I41_RS05510	ENOG4105D5D	udp-galactopyranose mutase
H0I41_RS05545	ENOG4105CG5	Glycosyl transferase (Group 1
H0I41_RS05555	ENOG4105D3Q	Sugar transferase
H0I41_RS05565	ENOG4107YJ4	chain length determinant protein
H0I41_RS05570	ENOG4105HTX	biosynthesis protein
H0I41_RS05575	ENOG4108KGH	TRANSCRIPTIONal
H0I41_RS05605	ENOG4107ZXU	DSBA oxidoreductase
H0I41_RS05620	ENOG4105KJF	protein tyrosine phosphatase
H0I41_RS05625	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
H0I41_RS05630	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
H0I41_RS05635	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
H0I41_RS05640	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
H0I41_RS05655	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
H0I41_RS05660	ENOG4105KQV	Binds directly to 16S ribosomal RNA (By similarity)
H0I41_RS05665	ENOG4105TQK	DNA polymerase iii, delta' subunit
H0I41_RS05670	ENOG4108EC8	DNA internalization-related competence protein ComEC
H0I41_RS05675	ENOG4105KQC	Competence protein
H0I41_RS05680	ENOG41063PX	domain protein
H0I41_RS05685	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
H0I41_RS05690	ENOG4106H78	methyltransferase
H0I41_RS05700	ENOG4105CNI	cell division protein FtsW
H0I41_RS05705	ENOG4105CI3	gtp-binding protein typa
H0I41_RS05710	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
H0I41_RS05715	ENOG4106EHS	UPF0356 protein
H0I41_RS05730	ENOG4105C7H	Helicase, RecD TraA family
H0I41_RS05745	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
H0I41_RS05755	ENOG4105C3J	Cysteine desulfurase
H0I41_RS05770	ENOG4108YZ4	nudix hydrolase
H0I41_RS05775	ENOG4105VEQ	Cold shock protein
H0I41_RS05780	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
H0I41_RS05800	ENOG4105VR5	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA (By similarity)
H0I41_RS05805	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
H0I41_RS05815	ENOG4108W8M	Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex (By similarity)
H0I41_RS05820	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
H0I41_RS05825	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
H0I41_RS05830	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
H0I41_RS05835	ENOG4105CJN	penicillin-binding protein
H0I41_RS05845	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
H0I41_RS05850	ENOG4108V6E	Cell division protein mraZ
H0I41_RS05875	ENOG4105DFF	Rod shape-determining protein mreb
H0I41_RS05880	ENOG4105W5Q	DNA repair protein (RadC
H0I41_RS05885	ENOG4105MN5	HAD-superfamily hydrolase subfamily IA variant 3
H0I41_RS05895	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
H0I41_RS05900	ENOG4105C52	Atpase, p-type (Transporting), had superfamily, subfamily ic
H0I41_RS05915	ENOG4105D8I	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS (By similarity)
H0I41_RS05920	ENOG4105C3J	Cysteine desulfurase
H0I41_RS05925	ENOG4105DGY	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization (By similarity)
H0I41_RS05930	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
H0I41_RS05940	ENOG4105D1H	recombination factor protein RarA
H0I41_RS05970	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
H0I41_RS05980	ENOG4105DFF	Rod shape-determining protein mreb
H0I41_RS05990	ENOG4105KNM	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
H0I41_RS05995	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
H0I41_RS06000	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
H0I41_RS06005	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
H0I41_RS06010	ENOG4107YZM	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
H0I41_RS06015	ENOG4107ZFM	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) (By similarity)
H0I41_RS06020	ENOG4105WS6	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
H0I41_RS06030	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
H0I41_RS06035	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
H0I41_RS06040	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
H0I41_RS06045	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
H0I41_RS06050	ENOG4107104	thymidine kinase
H0I41_RS06055	ENOG4105DMS	mur ligase
H0I41_RS06080	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
H0I41_RS06085	ENOG4107QYV	phosphohexose isomerase
H0I41_RS06100	ENOG4105BZU	Histidine kinase
H0I41_RS06105	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
H0I41_RS06115	ENOG4105DG6	mannose-6-phosphate isomerase
H0I41_RS06310	ENOG4108IYT	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
H0I41_RS06320	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
H0I41_RS06360	ENOG4105CDY	transcriptional regulatory protein
H0I41_RS06370	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
H0I41_RS06380	ENOG4108EUD	Lysophospholipase
H0I41_RS06395	ENOG4106A8V	Protein CrcB homolog
H0I41_RS06400	ENOG41084I6	Protein CrcB homolog
H0I41_RS06405	ENOG410667J	hydrolase
H0I41_RS06410	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
H0I41_RS06420	ENOG4105C8B	TIGR00159 family
H0I41_RS06430	ENOG4108I5D	sulfate abc transporter
H0I41_RS06440	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
H0I41_RS06445	ENOG4105D4A	Cell wall formation (By similarity)
H0I41_RS06455	ENOG4105K8N	protein family UPF0079, ATPase
H0I41_RS06460	ENOG4108IJ2	phosphate acetyltransferase
H0I41_RS06465	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
H0I41_RS06470	ENOG410667J	hydrolase
H0I41_RS06495	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
H0I41_RS06500	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
H0I41_RS06510	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
H0I41_RS06515	ENOG4105CP7	Triose-phosphate isomerase
H0I41_RS06520	ENOG4105BZA	Phosphoglycerate kinase
H0I41_RS06525	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
H0I41_RS06535	ENOG4105E5D	amino acid
H0I41_RS06540	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
H0I41_RS06545	ENOG4105CIE	May be required for sporulation (By similarity)
H0I41_RS06555	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
H0I41_RS06565	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
H0I41_RS06570	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
H0I41_RS06580	ENOG4105ENN	converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity)
H0I41_RS06585	ENOG4105CKN	UDP-glucose-hexose-1-phosphate uridylyltransferase
H0I41_RS06590	ENOG4105CRD	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity)
H0I41_RS06595	ENOG4105C4C	beta-galactosidase
H0I41_RS06600	ENOG4107RBJ	symporter
H0I41_RS06605	ENOG4105CQ4	Transcriptional regulator
H0I41_RS06610	ENOG4105CNT	hydrolase family 2
H0I41_RS06615	ENOG4105IKJ	beta-galactosidase small subunit
H0I41_RS06620	ENOG4105CMR	udp-glucose 4-epimerase
H0I41_RS06635	ENOG4105C3M	thioredoxin reductase
H0I41_RS06640	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
H0I41_RS06645	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
H0I41_RS06650	ENOG4105D1C	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion (By similarity)
H0I41_RS06665	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
H0I41_RS06685	ENOG4108ZK7	protein family UPF0029, Impact, N-terminal protein
H0I41_RS06690	ENOG4105ESV	Glycosyl transferase, family 4
H0I41_RS06695	ENOG4105E4Y	Endoribonuclease that initiates mRNA decay (By similarity)
H0I41_RS06700	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
H0I41_RS06705	ENOG4105BZQ	cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase
H0I41_RS06715	ENOG4105CHR	reductase
H0I41_RS06730	ENOG4105CNU	cell division protein FtsK
H0I41_RS06740	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
H0I41_RS06755	ENOG4105HHQ	6-phosphogluconolactonase (EC 3.1.1.31)
H0I41_RS06780	ENOG4105EMS	pseudouridine synthase
H0I41_RS06785	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
H0I41_RS06795	ENOG4105MIX	Adenylate cyclase
H0I41_RS06815	ENOG41090SU	Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress (By similarity)
H0I41_RS06820	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
H0I41_RS06825	ENOG4105KRI	phosphocarrier protein (HPr
H0I41_RS06835	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
H0I41_RS06845	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
H0I41_RS06850	ENOG4105C37	(CBS) domain
H0I41_RS06865	ENOG4105EVI	UPF0374 protein
H0I41_RS06870	ENOG410902V	Modulates RecA activity (By similarity)
H0I41_RS06875	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
H0I41_RS06880	ENOG4105F99	Hydroxymethylglutaryl-CoA synthase
H0I41_RS06905	ENOG4108HCJ	Hydrolase
H0I41_RS06910	ENOG4105CZM	Major Facilitator
H0I41_RS06915	ENOG4105C5F	glutamine synthetase
H0I41_RS06920	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
H0I41_RS06945	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
H0I41_RS06950	ENOG4105WDJ	50S ribosomal protein L33
H0I41_RS06955	ENOG4107RF6	penicillin-binding protein
H0I41_RS06975	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
H0I41_RS06980	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
H0I41_RS06990	ENOG4108RWN	rrna methyltransferase
H0I41_RS06995	ENOG410855V	Acylphosphatase
H0I41_RS07000	ENOG4107XQC	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins (By similarity)
H0I41_RS07005	ENOG4105GR3	Histidine kinase
H0I41_RS07010	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
H0I41_RS07020	ENOG4105CDE	UPF0348 protein
H0I41_RS07030	ENOG4108WF2	Metal Dependent Phosphohydrolase
H0I41_RS07035	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
H0I41_RS07040	ENOG4105CQW	ribosome biogenesis GTPase YqeH
H0I41_RS07045	ENOG4108WJV	had superfamily (subfamily IIIa) phosphatase
H0I41_RS07050	ENOG4105EKD	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity)
H0I41_RS07055	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
H0I41_RS07060	ENOG4105VJV	50s ribosomal protein L35
H0I41_RS07065	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
H0I41_RS07085	ENOG4105C22	threonyL-tRNA synthetase
H0I41_RS07100	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
H0I41_RS07105	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
H0I41_RS07110	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
H0I41_RS07115	ENOG4105C2M	dna polymerase I
H0I41_RS07130	ENOG4105DFU	Cell wall formation (By similarity)
H0I41_RS07135	ENOG4106N3A	copper homeostasis protein cutc
H0I41_RS07140	ENOG4108VDD	TRNA binding domain protein
H0I41_RS07155	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
H0I41_RS07170	ENOG4105K59	histidine triad (HIT) protein
H0I41_RS07185	ENOG4107UUG	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity)
H0I41_RS07190	ENOG4105EQI	Metal Dependent Phosphohydrolase
H0I41_RS07200	ENOG4107RFY	SbcCD D subunit
H0I41_RS07205	ENOG4105WZB	UPF0342 protein
H0I41_RS07210	ENOG4105BZ4	penicillin-binding protein
H0I41_RS07215	ENOG4108YBP	pseudouridine synthase
H0I41_RS07235	ENOG4105K18	The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane (By similarity)
H0I41_RS07240	ENOG4105DT3	PTS system, galactitol-specific IIc component
H0I41_RS07280	ENOG4108R0M	Aminoglycoside
H0I41_RS07300	ENOG4105IJJ	transcriptional regulator, crp fnr family
H0I41_RS07310	ENOG4105C59	p-type ATPase
H0I41_RS07325	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
H0I41_RS07335	ENOG4105DA5	(ABC) transporter
H0I41_RS07340	ENOG4105DFD	Na H antiporter
H0I41_RS07350	ENOG4108V7D	UPF0397 protein
H0I41_RS07355	ENOG4108JJB	ABC transporter
H0I41_RS07395	ENOG410667J	hydrolase
H0I41_RS07400	ENOG4105D7V	transposase
H0I41_RS07410	ENOG4105CBD	Diacylglycerol kinase
H0I41_RS07415	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
H0I41_RS07420	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
H0I41_RS07425	ENOG4105VB5	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
H0I41_RS07435	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
H0I41_RS07440	ENOG4105C4R	Atp-dependent dna helicase
H0I41_RS07445	ENOG4108ZW7	flagellar rod assembly protein muramidase flgj
H0I41_RS07475	ENOG4107SJB	teichoic acid biosynthesis
H0I41_RS07485	ENOG4105BZ1	(ABC) transporter
H0I41_RS07495	ENOG4106F1P	AAA ATPase, central domain protein
H0I41_RS07500	ENOG4107RA1	nh(3)-dependent nad( ) synthetase
H0I41_RS07505	ENOG4105DAP	Nicotinate phosphoribosyltransferase
H0I41_RS07610	ENOG4107QN2	dihydrolipoyl dehydrogenase
H0I41_RS07620	ENOG4105CMR	udp-glucose 4-epimerase
H0I41_RS07625	ENOG4108I5C	dEAD DEAH box helicase
H0I41_RS07650	ENOG4105C0A	alcohol dehydrogenase
H0I41_RS07655	ENOG4105C85	amino acid
H0I41_RS07775	ENOG4105E0M	Sulfatase
H0I41_RS07785	ENOG4105W2C	Glycosyl transferase
H0I41_RS07790	ENOG4105BZF	Glycosyl transferase (Group 1
H0I41_RS07950	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
H0I41_RS07955	ENOG4105D9U	N-acetyltransferase
H0I41_RS07975	ENOG4105C26	Dehydrogenase
H0I41_RS07990	ENOG410667J	hydrolase
H0I41_RS07995	ENOG4105EYF	MMPL domain protein
H0I41_RS08000	ENOG4108IG5	Transcriptional regulator
H0I41_RS08010	ENOG4105RD7	BadF BadG BcrA BcrD
H0I41_RS08025	ENOG4108U05	Transcriptional regulator
H0I41_RS08040	ENOG4105CN5	Metallo-Beta-Lactamase
H0I41_RS08050	ENOG4107Z33	ABC transporter, permease
H0I41_RS08060	ENOG4105DZW	Dipeptidase
H0I41_RS08080	ENOG4105DE5	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity)
H0I41_RS08100	ENOG4105D42	Cleaves the N-terminal amino acid of tripeptides (By similarity)
H0I41_RS08120	ENOG4105M2E	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
H0I41_RS08130	ENOG4105F3R	pts system mannose fructose sorbose family iid
H0I41_RS08135	ENOG4105ETZ	PTS System
H0I41_RS08140	ENOG4108UZY	PTS System
H0I41_RS08145	ENOG4105FDP	GntR family transcriptional regulator
H0I41_RS08170	ENOG4106762	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD) (By similarity)
H0I41_RS08180	ENOG4105F3R	pts system mannose fructose sorbose family iid
H0I41_RS08190	ENOG4105DAS	pts system
H0I41_RS08200	ENOG4108UZ3	Transporter
H0I41_RS08215	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
H0I41_RS08220	ENOG4105CS9	pantothenic acid kinase
H0I41_RS08235	ENOG4105EEM	helicase
H0I41_RS08255	ENOG4106KNT	transcriptional regulator
H0I41_RS08260	ENOG4105C9S	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P) (By similarity)
H0I41_RS08265	ENOG4108IIZ	The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane
H0I41_RS08270	ENOG4105CGK	Exodeoxyribonuclease III
H0I41_RS08280	ENOG4105DKJ	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
H0I41_RS08290	ENOG4105C19	ABC transporter
H0I41_RS08295	ENOG4105E5D	amino acid
H0I41_RS08310	ENOG4108IUW	ABC transporter
H0I41_RS08320	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
H0I41_RS08335	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
H0I41_RS08355	ENOG4105MTF	NrdI protein
H0I41_RS08385	ENOG4105DWK	Membrane
H0I41_RS08390	ENOG4105C5H	ABC transporter
H0I41_RS08405	ENOG4108KGH	TRANSCRIPTIONal
H0I41_RS08410	ENOG4105DPN	Oligoendopeptidase f
H0I41_RS08420	ENOG4105CC5	ABC transporter
H0I41_RS08425	ENOG4105FDK	ABC transporter
H0I41_RS08435	ENOG41082YX	Transcriptional regulator, arsr family
H0I41_RS08440	ENOG4108HCJ	Hydrolase
H0I41_RS08450	ENOG4105DM4	PTS System
H0I41_RS08455	ENOG4105DE4	1-phosphofructokinase
H0I41_RS08460	ENOG4105E98	transcriptional regulator DeoR family
H0I41_RS08470	ENOG4105RHA	ABC transporter, permease
H0I41_RS08475	ENOG4108IUX	(ABC) transporter
H0I41_RS08480	ENOG4105CG9	aspartate racemase
H0I41_RS08485	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
H0I41_RS08490	ENOG4105BZU	Histidine kinase
H0I41_RS08500	ENOG4105BZ1	(ABC) transporter
H0I41_RS08505	ENOG4105BZ1	(ABC) transporter
H0I41_RS08515	ENOG4105C3G	gtp-binding protein
H0I41_RS08520	ENOG4105VDK	protein, conserved in bacteria
H0I41_RS08525	ENOG4105FA0	parb-like partition protein
H0I41_RS08530	ENOG4107QJE	Chromosome Partitioning Protein
H0I41_RS08540	ENOG4105D28	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
H0I41_RS08565	ENOG4108YYH	Nadph-dependent fmn reductase
H0I41_RS08570	ENOG4107U8T	Nadph-dependent fmn reductase
H0I41_RS08585	ENOG4105DZW	Dipeptidase
H0I41_RS08590	ENOG4105CS2	ec 3.2.1.21
H0I41_RS08595	ENOG4105C5Y	PTS System
H0I41_RS08600	ENOG4105CID	antiterminator
H0I41_RS08605	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
H0I41_RS08620	ENOG4105DKJ	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
H0I41_RS08630	ENOG4108EMS	branched-chain alpha-keto acid dehydrogenase subunit E2
H0I41_RS08635	ENOG4105D1Q	UPF0246 protein
H0I41_RS08655	ENOG4105CK1	PTS System
H0I41_RS08680	ENOG4105FF2	Type I DHQase
H0I41_RS08695	ENOG4108Z86	Glutamine amidotransferase
H0I41_RS08700	ENOG4105BZ1	(ABC) transporter
H0I41_RS08705	ENOG4108UVJ	appr-1-p processing domain protein
H0I41_RS08715	ENOG4105C5Y	PTS System
H0I41_RS08720	ENOG4108HKT	sucrose-6-phosphate hydrolase
H0I41_RS08730	ENOG4105M2Z	protein tyrosine serine phosphatase
H0I41_RS08735	ENOG4105DWF	phosphomethylpyrimidine kinase
H0I41_RS08740	ENOG4105F1K	Glutamine amidotransferase
H0I41_RS08745	ENOG4105CUB	amino acid
H0I41_RS08750	ENOG4108UZ3	Transporter
H0I41_RS08755	ENOG4105CU9	asparagine synthetase A
H0I41_RS08765	ENOG4108Z86	Glutamine amidotransferase
H0I41_RS08785	ENOG4105F3R	pts system mannose fructose sorbose family iid
H0I41_RS08790	ENOG4105ETZ	PTS System
H0I41_RS08890	ENOG4105CUB	amino acid
H0I41_RS08915	ENOG410605W	Major Facilitator
H0I41_RS08925	ENOG4108M4D	D-alanyl-lipoteichoic acid biosynthesis protein DltD
H0I41_RS08930	ENOG4105X96	Involved in the biosynthesis of D-alanyl-lipoteichoic acid (LTA). Activated D-alanyl-Dcp donates its D-alanyl substituent to membrane-associated LTA (By similarity)
H0I41_RS08935	ENOG4105CK0	Membrane bOund o-acyl transferase mboat family protein
H0I41_RS08940	ENOG4108IQD	Involved in the biosynthesis of D-alanyl-lipoteichoic acid (LTA). Catalyzes an ATP-dependent two-step reaction where it forms a high energy D-alanyl AMP intermediate and transfers the alanyl residues from AMP to Dcp (By similarity)
H0I41_RS09000	ENOG4105BZ1	(ABC) transporter
H0I41_RS09010	ENOG4108KN7	Removes 5-oxoproline from various penultimate amino acid residues except L-proline (By similarity)
H0I41_RS09040	ENOG4105DT3	PTS system, galactitol-specific IIc component
H0I41_RS09065	ENOG4105C4M	(Ubiquinol oxidase) subunit I
H0I41_RS09070	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
H0I41_RS09075	ENOG4108JJ9	ABC, transporter
H0I41_RS09080	ENOG4108JJ8	(ABC) transporter
H0I41_RS09095	ENOG4105DIH	basic membrane
H0I41_RS09110	ENOG4105E15	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
H0I41_RS09115	ENOG4105C5Y	PTS System
H0I41_RS09125	ENOG4105CV8	reductase
H0I41_RS09130	ENOG4105CKA	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion (By similarity)
H0I41_RS09135	ENOG4105ZMH	deoxynucleoside kinase
H0I41_RS09140	ENOG4105ZMH	deoxynucleoside kinase
H0I41_RS09150	ENOG4105C7N	Xanthine uracil vitamin C permease
H0I41_RS09155	ENOG4108Z6Z	Transcriptional regulator
H0I41_RS09160	ENOG4105C7N	Xanthine uracil vitamin C permease
H0I41_RS09165	ENOG4105C7N	Xanthine uracil vitamin C permease
H0I41_RS09175	ENOG4107YDN	peptide deformylase
H0I41_RS09190	ENOG4105NA0	Transcriptional regulator
H0I41_RS09205	ENOG4105C59	p-type ATPase
H0I41_RS09225	ENOG4107UUG	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity)
H0I41_RS09230	ENOG4105E5D	amino acid
H0I41_RS09240	ENOG4105CXI	aluminum resistance protein
H0I41_RS09255	ENOG4105C54	Major Facilitator superfamily
H0I41_RS09265	ENOG4105CPN	adenine deaminase
H0I41_RS09270	ENOG4105C7N	Xanthine uracil vitamin C permease
H0I41_RS09275	ENOG4105EKD	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity)
H0I41_RS09285	ENOG4105C98	muts2 protein
H0I41_RS09295	ENOG4105C7Q	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity)
H0I41_RS09300	ENOG4105C7K	acetolactate synthase
H0I41_RS09305	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
H0I41_RS09310	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
H0I41_RS09315	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
H0I41_RS09320	ENOG4105M7T	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)