locus-tag	class	description
H0G69_RS00010	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
H0G69_RS00015	ENOG410848D	S4 domain protein YaaA
H0G69_RS00025	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
H0G69_RS00030	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
H0G69_RS00040	ENOG4108UUM	single-stranded DNA-binding protein
H0G69_RS00060	ENOG4105CDU	Replicative dna helicase
H0G69_RS00065	ENOG410605W	Major Facilitator
H0G69_RS00085	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
H0G69_RS00090	ENOG4105BZU	Histidine kinase
H0G69_RS00105	ENOG4105Q2H	domain protein
H0G69_RS00110	ENOG4105C0H	protease
H0G69_RS00120	ENOG4108Z40	Transcriptional regulator
H0G69_RS00125	ENOG4107T7U	Sulfatase
H0G69_RS00165	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
H0G69_RS00180	ENOG4107SJ1	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides (By similarity)
H0G69_RS00200	ENOG4106EG9	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity)
H0G69_RS00225	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
H0G69_RS00230	ENOG4105CWM	branched-chain amino acid transport system II carrier protein
H0G69_RS00235	ENOG4107EFR	Flavocytochrome c
H0G69_RS00240	ENOG4108YYH	Nadph-dependent fmn reductase
H0G69_RS00245	ENOG4108M4D	D-alanyl-lipoteichoic acid biosynthesis protein DltD
H0G69_RS00255	ENOG4105CK0	Membrane bOund o-acyl transferase mboat family protein
H0G69_RS00260	ENOG4108IQD	Involved in the biosynthesis of D-alanyl-lipoteichoic acid (LTA). Catalyzes an ATP-dependent two-step reaction where it forms a high energy D-alanyl AMP intermediate and transfers the alanyl residues from AMP to Dcp (By similarity)
H0G69_RS00275	ENOG4105EYH	Exonuclease
H0G69_RS00285	ENOG410605W	Major Facilitator
H0G69_RS00305	ENOG4105E5Q	amino acid AbC transporter
H0G69_RS00310	ENOG4105CDA	abc transporter atp-binding protein
H0G69_RS00315	ENOG4105C85	amino acid
H0G69_RS00320	ENOG4105D5Q	Arginine ornithine antiporter
H0G69_RS00325	ENOG4105CHM	Aminotransferase
H0G69_RS00335	ENOG4105DU0	nucleoside hydrolase
H0G69_RS00350	ENOG4105FA0	parb-like partition protein
H0G69_RS00355	ENOG4105VDK	protein, conserved in bacteria
H0G69_RS00360	ENOG4105C3G	gtp-binding protein
H0G69_RS00380	ENOG4108KGH	TRANSCRIPTIONal
H0G69_RS00385	ENOG4105HTX	biosynthesis protein
H0G69_RS00390	ENOG4107YJ4	chain length determinant protein
H0G69_RS00395	ENOG4108RB3	Capsular polysaccharide biosynthesis protein
H0G69_RS00400	ENOG4108IAJ	Nad-dependent epimerase dehydratase
H0G69_RS00410	ENOG4108RYC	glycosyltransferase
H0G69_RS00420	ENOG4105HTX	biosynthesis protein
H0G69_RS00445	ENOG4105K64	Glycosyl transferase, family 2
H0G69_RS00450	ENOG4107SBE	Glycosyl transferase (Group 1
H0G69_RS00470	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
H0G69_RS00510	ENOG4106F5Q	Membrane
H0G69_RS00515	ENOG4105CP9	extracellular ligand-binding receptor
H0G69_RS00520	ENOG4105C32	Amino acid ABC transporter (Permease)
H0G69_RS00525	ENOG4105CF8	branched-chain amino acid ABC transporter, permease
H0G69_RS00530	ENOG4105C0Z	ABC transporter
H0G69_RS00535	ENOG4108IV0	ABC, transporter
H0G69_RS00545	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
H0G69_RS00550	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
H0G69_RS00555	ENOG4105C83	adenylosuccinate lyase
H0G69_RS00565	ENOG4105VR9	phosphoribosylformylglycinamidine synthase
H0G69_RS00580	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
H0G69_RS00590	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
H0G69_RS00615	ENOG4105DKJ	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
H0G69_RS00680	ENOG4107QHE	Choloylglycine hydrolase
H0G69_RS00725	ENOG4105EEM	helicase
H0G69_RS00730	ENOG4105C9X	ppx gppa phosphatase
H0G69_RS00745	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
H0G69_RS00750	ENOG4105I3N	Conserved Protein
H0G69_RS00755	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
H0G69_RS00760	ENOG4105F8V	Hydrolase, tatD family
H0G69_RS00765	ENOG4105HVR	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step (By similarity)
H0G69_RS00775	ENOG4105W42	Veg protein
H0G69_RS00790	ENOG4105D5Q	Arginine ornithine antiporter
H0G69_RS00810	ENOG4105DFT	pur operon repressor
H0G69_RS00820	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
H0G69_RS00840	ENOG4105DAP	Nicotinate phosphoribosyltransferase
H0G69_RS00850	ENOG4105DCI	Phosphohydrolase
H0G69_RS00865	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
H0G69_RS00870	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
H0G69_RS00880	ENOG4108Z6X	(sortase) family
H0G69_RS00885	ENOG4105KJF	protein tyrosine phosphatase
H0G69_RS00890	ENOG4108V0P	LemA family
H0G69_RS00900	ENOG4107EES	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide the precursor of murein (By similarity)
H0G69_RS00905	ENOG4105C1J	atp-dependent rna helicase
H0G69_RS00920	ENOG4108YZM	Toxic component of a toxin-antitoxin (TA) module (By similarity)
H0G69_RS00935	ENOG4108JA2	transcriptioN-repair coupling factor
H0G69_RS00940	ENOG41082I2	s4 domain protein
H0G69_RS00950	ENOG41060GV	RNA binding s1 domain protein
H0G69_RS00955	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
H0G69_RS00975	ENOG410605W	Major Facilitator
H0G69_RS00980	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
H0G69_RS01020	ENOG4108UIC	UPF0340 protein
H0G69_RS01025	ENOG4105DUX	Transporter
H0G69_RS01060	ENOG4105CG9	aspartate racemase
H0G69_RS01070	ENOG4105DAP	Nicotinate phosphoribosyltransferase
H0G69_RS01085	ENOG410906U	SprT-like
H0G69_RS01095	ENOG4105CNT	hydrolase family 2
H0G69_RS01100	ENOG4105IKJ	beta-galactosidase small subunit
H0G69_RS01110	ENOG4108K79	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
H0G69_RS01120	ENOG4105CTZ	aminopeptidase c
H0G69_RS01135	ENOG4107Z0P	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity)
H0G69_RS01140	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
H0G69_RS01145	ENOG4105CTP	PilT protein domain protein
H0G69_RS01165	ENOG4105KEB	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
H0G69_RS01170	ENOG4105C2N	RNA methyltransferase TrmH family group 3
H0G69_RS01180	ENOG4105DEU	major facilitator superfamily
H0G69_RS01200	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
H0G69_RS01215	ENOG4107R7I	amino acid
H0G69_RS01235	ENOG4105C0A	alcohol dehydrogenase
H0G69_RS01245	ENOG4105CWM	branched-chain amino acid transport system II carrier protein
H0G69_RS01255	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
H0G69_RS01260	ENOG4105WAZ	(Glutaredoxin-like protein) NrdH
H0G69_RS01265	ENOG4108Z6B	deaminase
H0G69_RS01275	ENOG4105C6E	dna polymerase iii
H0G69_RS01280	ENOG410816I	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
H0G69_RS01300	ENOG4105X0R	protein from nitrogen regulatory protein P-II
H0G69_RS01305	ENOG4105FA2	dna polymerase iii
H0G69_RS01310	ENOG41063V3	Involved in initiation control of chromosome replication (By similarity)
H0G69_RS01330	ENOG4105CUU	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity)
H0G69_RS01335	ENOG4105C9X	ppx gppa phosphatase
H0G69_RS01340	ENOG4105CMR	udp-glucose 4-epimerase
H0G69_RS01345	ENOG41072GX	Peptidase M22 Glycoprotease
H0G69_RS01360	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
H0G69_RS01365	ENOG41067TZ	transcriptional regulator, MarR family
H0G69_RS01375	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
H0G69_RS01385	ENOG4105CHR	reductase
H0G69_RS01390	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
H0G69_RS01395	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
H0G69_RS01400	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
H0G69_RS01405	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
H0G69_RS01420	ENOG4105CSJ	Enoyl- acyl-carrier-protein reductase NADH
H0G69_RS01425	ENOG4108JIJ	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second (By similarity)
H0G69_RS01430	ENOG4105CHM	Aminotransferase
H0G69_RS01435	ENOG41080Y5	BioY family
H0G69_RS01440	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
H0G69_RS01450	ENOG4108JZF	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
H0G69_RS01455	ENOG4105C5H	ABC transporter
H0G69_RS01475	ENOG4107QTZ	amino acid
H0G69_RS01480	ENOG4105C0X	amino acid
H0G69_RS01495	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
H0G69_RS01500	ENOG4108ZK7	protein family UPF0029, Impact, N-terminal protein
H0G69_RS01530	ENOG41067S9	phage shock protein C, PspC
H0G69_RS01535	ENOG41086DT	Membrane protein of unknown function
H0G69_RS01560	ENOG4105C3M	thioredoxin reductase
H0G69_RS01570	ENOG410667J	hydrolase
H0G69_RS01605	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
H0G69_RS01610	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
H0G69_RS01615	ENOG4105E2X	shikimate dehydrogenase
H0G69_RS01620	ENOG4105FF2	Type I DHQase
H0G69_RS01630	ENOG4105CHW	UPF0052 protein
H0G69_RS01650	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
H0G69_RS01660	ENOG4105CP7	Triose-phosphate isomerase
H0G69_RS01680	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
H0G69_RS01700	ENOG4108IJ2	phosphate acetyltransferase
H0G69_RS01705	ENOG4105K8N	protein family UPF0079, ATPase
H0G69_RS01715	ENOG4105CQ4	Transcriptional regulator
H0G69_RS01720	ENOG4107RBJ	symporter
H0G69_RS01725	ENOG4105C4C	beta-galactosidase
H0G69_RS01730	ENOG4105DE5	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity)
H0G69_RS01735	ENOG4105CGK	Exodeoxyribonuclease III
H0G69_RS01765	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
H0G69_RS01775	ENOG4105EXC	Acyl-transferase
H0G69_RS01780	ENOG410667J	hydrolase
H0G69_RS01785	ENOG4105VRS	hydrolase family 18
H0G69_RS01795	ENOG4105HMI	Membrane
H0G69_RS01805	ENOG4105C3J	Cysteine desulfurase
H0G69_RS01825	ENOG4107SC7	Inner membrane transporter yjeM
H0G69_RS01840	ENOG4105S7A	ErfK ybiS ycfS ynhG family protein
H0G69_RS01845	ENOG4108RYK	Nad-dependent epimerase dehydratase
H0G69_RS01850	ENOG4108Z40	Transcriptional regulator
H0G69_RS01860	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
H0G69_RS01865	ENOG4105BZU	Histidine kinase
H0G69_RS01870	ENOG4105EV1	Ribose uptake protein RbsU
H0G69_RS01880	ENOG4105D49	3-dehydroquinate synthase
H0G69_RS01885	ENOG4108JPM	phospho-2-dehydro-3-deoxyheptonate aldolase
H0G69_RS01890	ENOG4107QNK	)-transporter
H0G69_RS01895	ENOG4105C93	Xylose Isomerase
H0G69_RS01900	ENOG4105CMG	Carbohydrate kinase
H0G69_RS01905	ENOG41075H3	AraC family transcriptional regulator
H0G69_RS01910	ENOG4105CT4	transporter
H0G69_RS01925	ENOG4105D3R	alkyl hydroperoxide reductase
H0G69_RS01945	ENOG4105CF7	AraC family transcriptional regulator
H0G69_RS01970	ENOG4105CMD	Transcriptional regulator, GntR family
H0G69_RS01975	ENOG4107QNK	)-transporter
H0G69_RS01980	ENOG4105CAC	Catalyzes the conversion of L-arabinose to L-ribulose (By similarity)
H0G69_RS01990	ENOG4105CUK	Alpha-N-arabinofuranosidase (EC 3.2.1.55)
H0G69_RS02005	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
H0G69_RS02025	ENOG4105CV8	reductase
H0G69_RS02030	ENOG4105X71	Membrane
H0G69_RS02060	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
H0G69_RS02070	ENOG4108V8F	Transcriptional regulator, MarR family
H0G69_RS02080	ENOG4105BZ1	(ABC) transporter
H0G69_RS02090	ENOG4108A04	Beta-lactamase
H0G69_RS02100	ENOG4105F1K	Glutamine amidotransferase
H0G69_RS02105	ENOG4105DMS	mur ligase
H0G69_RS02110	ENOG4107104	thymidine kinase
H0G69_RS02120	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
H0G69_RS02125	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
H0G69_RS02185	ENOG4105KNM	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
H0G69_RS02195	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
H0G69_RS02215	ENOG4105CNI	cell division protein FtsW
H0G69_RS02220	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
H0G69_RS02225	ENOG4105D01	(LipO)protein
H0G69_RS02230	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
H0G69_RS02235	ENOG4108UMI	ABC transporter, permease
H0G69_RS02260	ENOG4107YZX	Universal stress protein
H0G69_RS02270	ENOG4105D1H	recombination factor protein RarA
H0G69_RS02290	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
H0G69_RS02310	ENOG4105DGY	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization (By similarity)
H0G69_RS02315	ENOG4105C3J	Cysteine desulfurase
H0G69_RS02325	ENOG4108V1J	Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity)
H0G69_RS02330	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
H0G69_RS02335	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
H0G69_RS02345	ENOG4105DFF	Rod shape-determining protein mreb
H0G69_RS02350	ENOG4105N3I	Involved in formation and maintenance of cell shape (By similarity)
H0G69_RS02360	ENOG4105E5Q	amino acid AbC transporter
H0G69_RS02365	ENOG4105CDA	abc transporter atp-binding protein
H0G69_RS02370	ENOG4106TNF	Periplasmic binding protein
H0G69_RS02390	ENOG4105BZQ	cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase
H0G69_RS02405	ENOG4105E4Y	Endoribonuclease that initiates mRNA decay (By similarity)
H0G69_RS02440	ENOG4105SFS	phosphoesterase RecJ domain protein
H0G69_RS02445	ENOG4105C1J	atp-dependent rna helicase
H0G69_RS02450	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
H0G69_RS02475	ENOG4105C98	muts2 protein
H0G69_RS02480	ENOG4105K63	Thioredoxin
H0G69_RS02495	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
H0G69_RS02500	ENOG4105M59	Phosphodiesterase, mj0936 family
H0G69_RS02510	ENOG4108HCJ	Hydrolase
H0G69_RS02515	ENOG4105D8X	mechanosensitive ion channel
H0G69_RS02530	ENOG4105DC7	peptidase M24
H0G69_RS02535	ENOG4105ETE	Transcriptional regulator (LacI family
H0G69_RS02560	ENOG4106855	Competence protein
H0G69_RS02595	ENOG4105D5G	Transposase
H0G69_RS02605	ENOG4105MMD	transcriptional regulator
H0G69_RS02610	ENOG4105D4U	had-superfamily hydrolase, subfamily iia
H0G69_RS02620	ENOG4105DQR	SNARE associated Golgi
H0G69_RS02760	ENOG41090SU	Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress (By similarity)
H0G69_RS02790	ENOG4105EMS	pseudouridine synthase
H0G69_RS02795	ENOG4105HHQ	6-phosphogluconolactonase (EC 3.1.1.31)
H0G69_RS02805	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
H0G69_RS02810	ENOG4105CNU	cell division protein FtsK
H0G69_RS02840	ENOG4105CJN	penicillin-binding protein
H0G69_RS02875	ENOG4105VR5	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA (By similarity)
H0G69_RS02885	ENOG4105DBK	s4 domain protein
H0G69_RS02900	ENOG4105VEQ	Cold shock protein
H0G69_RS02905	ENOG4108YZ4	nudix hydrolase
H0G69_RS02930	ENOG4108TGR	phosphatase
H0G69_RS02945	ENOG4105C7H	Helicase, RecD TraA family
H0G69_RS02950	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
H0G69_RS02955	ENOG41090SU	Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress (By similarity)
H0G69_RS02970	ENOG4109050	May catalyze the ATP-dependent phosphorylation of lipids other than diacylglycerol (DAG)
H0G69_RS02995	ENOG4105ECY	inositol monophosphatase
H0G69_RS03000	ENOG4105CI3	gtp-binding protein typa
H0G69_RS03005	ENOG4105CNI	cell division protein FtsW
H0G69_RS03010	ENOG4105WUC	UPF0298 protein
H0G69_RS03015	ENOG4106H78	methyltransferase
H0G69_RS03025	ENOG41063PX	domain protein
H0G69_RS03030	ENOG4105KQC	Competence protein
H0G69_RS03035	ENOG4108UK2	deaminase
H0G69_RS03040	ENOG4105EGY	DNA internalization-related competence protein ComEC Rec2
H0G69_RS03045	ENOG4105TQK	DNA polymerase iii, delta' subunit
H0G69_RS03075	ENOG4105C7N	Xanthine uracil vitamin C permease
H0G69_RS03080	ENOG4105CPN	adenine deaminase
H0G69_RS03115	ENOG4105EMU	Dehydrogenase
H0G69_RS03120	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
H0G69_RS03125	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
H0G69_RS03140	ENOG4108W76	histidinol phosphate phosphatase hisj family
H0G69_RS03150	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
H0G69_RS03155	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
H0G69_RS03165	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
H0G69_RS03170	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
H0G69_RS03175	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
H0G69_RS03180	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
H0G69_RS03285	ENOG4105CXT	aspartate transcarbamylase
H0G69_RS03290	ENOG4105CD3	dihydroorotase
H0G69_RS03300	ENOG4105VUC	UPF0237 protein
H0G69_RS03305	ENOG4105CAG	UPF0210 protein
H0G69_RS03330	ENOG4105C6X	Major Facilitator
H0G69_RS03375	ENOG4108UQV	Membrane
H0G69_RS03380	ENOG4105DZW	Dipeptidase
H0G69_RS03395	ENOG4105CHU	acetyl-coa acetyltransferase
H0G69_RS03400	ENOG410841Q	phosphoesterase PA-phosphatase related protein
H0G69_RS03415	ENOG4108JQ1	Dehydrogenase
H0G69_RS03425	ENOG4105CVJ	phosphoglycerate mutase
H0G69_RS03430	ENOG4105C52	Atpase, p-type (Transporting), had superfamily, subfamily ic
H0G69_RS03440	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
H0G69_RS03445	ENOG4108U05	Transcriptional regulator
H0G69_RS03455	ENOG4105F99	Hydroxymethylglutaryl-CoA synthase
H0G69_RS03470	ENOG4105VPS	UPF0291 protein
H0G69_RS03475	ENOG4105VXM	UPF0154 protein
H0G69_RS03480	ENOG4105F6E	Acyl-transferase
H0G69_RS03485	ENOG41060K3	Methyltransferase
H0G69_RS03490	ENOG4105VC4	domain protein
H0G69_RS03495	ENOG4105C5I	Dehydrogenase
H0G69_RS03500	ENOG4105C5I	Dehydrogenase
H0G69_RS03525	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
H0G69_RS03530	ENOG4105KNE	Phosphatidate cytidylyltransferase
H0G69_RS03535	ENOG4105DZP	Membrane-associated zinc metalloprotease
H0G69_RS03555	ENOG4105CHV	Transcription elongation factor NusA
H0G69_RS03560	ENOG4105VZN	Nucleic-acid-binding protein implicated in transcription termination
H0G69_RS03585	ENOG4105DTN	riboflavin biosynthesis protein ribF
H0G69_RS03590	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
H0G69_RS03600	ENOG4105D7V	transposase
H0G69_RS03610	ENOG4105DQ6	Transposase
H0G69_RS03625	ENOG4105CFN	oxalyl-CoA decarboxylase
H0G69_RS03635	ENOG4108N2Y	auxin Efflux
H0G69_RS03645	ENOG4105WKZ	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease (By similarity)
H0G69_RS03650	ENOG4105GIM	CRISPR-associated protein cas6
H0G69_RS03665	ENOG4105DQ6	Transposase
H0G69_RS03680	ENOG4108W8W	CRISPR-associated RAMP protein, Csm3 family
H0G69_RS03685	ENOG4108T47	CRISPR-associated RAMP protein, Csm4 family
H0G69_RS03690	ENOG4105G15	CRISPR-associated RAMP protein, Csm5 family
H0G69_RS03700	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
H0G69_RS03715	ENOG4108UW5	maltose o-acetyltransferase
H0G69_RS03730	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
H0G69_RS03750	ENOG4105C7K	acetolactate synthase
H0G69_RS03775	ENOG4107TVK	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
H0G69_RS03785	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
H0G69_RS03800	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
H0G69_RS03820	ENOG4105EFU	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin (By similarity)
H0G69_RS03830	ENOG4105KTH	gatB Yqey
H0G69_RS03835	ENOG4105C9A	Phoh family
H0G69_RS03850	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
H0G69_RS03860	ENOG4108HMW	glycyl-tRNA synthetase, alpha subunit
H0G69_RS03870	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
H0G69_RS03875	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
H0G69_RS03880	ENOG4105DZC	cytosine deaminase
H0G69_RS03885	ENOG4105DQW	permease for cytosine purines, uracil, thiamine, allantoin
H0G69_RS03890	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
H0G69_RS03895	ENOG4105CFH	Aspartokinase
H0G69_RS03920	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
H0G69_RS03925	ENOG4105CHM	Aminotransferase
H0G69_RS03930	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
H0G69_RS03940	ENOG4105EGD	dinuclear metal center protein, YbgI family
H0G69_RS03950	ENOG4105CV8	reductase
H0G69_RS03965	ENOG4105E8V	Alpha Beta Hydrolase Fold protein
H0G69_RS03970	ENOG4105C0B	DNA polymerase III (alpha subunit)
H0G69_RS03975	ENOG4105CA9	Pyruvate kinase
H0G69_RS03985	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
H0G69_RS03995	ENOG4108KVX	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves (By similarity)
H0G69_RS04000	ENOG4105K8I	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity)
H0G69_RS04005	ENOG4105FE9	pseudouridine synthase
H0G69_RS04010	ENOG4108SAX	Membrane
H0G69_RS04020	ENOG4105C9U	ATP-dependent DNA helicase RecQ
H0G69_RS04035	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
H0G69_RS04065	ENOG4105C5H	ABC transporter
H0G69_RS04080	ENOG4108UT2	hemolysin iii
H0G69_RS04085	ENOG4108RCR	degv family
H0G69_RS04090	ENOG4108UK1	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant (By similarity)
H0G69_RS04095	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
H0G69_RS04100	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
H0G69_RS04105	ENOG4105CPQ	Dehydrogenase
H0G69_RS04110	ENOG4105VND	Ribonuclease
H0G69_RS04120	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
H0G69_RS04125	ENOG4105C34	Pseudouridine synthase
H0G69_RS04130	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
H0G69_RS04135	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
H0G69_RS04140	ENOG4105DG4	malate L-lactate dehydrogenase
H0G69_RS04150	ENOG4105EPR	degv family
H0G69_RS04165	ENOG4108UTW	Plays a role in the regulation of phosphate uptake
H0G69_RS04170	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
H0G69_RS04175	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
H0G69_RS04180	ENOG4105E2Z	phosphate ABC transporter (Permease
H0G69_RS04185	ENOG4105C8U	phosphate abc transporter
H0G69_RS04200	ENOG4105C37	(CBS) domain
H0G69_RS04210	ENOG4105NA0	Transcriptional regulator
H0G69_RS04240	ENOG4109025	Glyoxalase Bleomycin resistance protein (Dioxygenase
H0G69_RS04245	ENOG4105WMR	Protein CrcB homolog
H0G69_RS04250	ENOG41082CG	Protein CrcB homolog
H0G69_RS04255	ENOG4107SC7	Inner membrane transporter yjeM
H0G69_RS04285	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
H0G69_RS04300	ENOG4105DZW	Dipeptidase
H0G69_RS04305	ENOG4105ZT7	DNA-entry nuclease
H0G69_RS04335	ENOG4105CMG	Carbohydrate kinase
H0G69_RS04345	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
H0G69_RS04355	ENOG4107R8N	Glycosyl transferase, family 2
H0G69_RS04370	ENOG4105F27	Major Facilitator
H0G69_RS04375	ENOG4105CQP	nitrilase cyanide hydratase and apolipoprotein n-acyltransferase
H0G69_RS04400	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
H0G69_RS04425	ENOG4106V2I	dimethylaminohydrolase
H0G69_RS04430	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
H0G69_RS04445	ENOG4105CSX	c4-dicarboxylate anaerobic carrier
H0G69_RS04450	ENOG4108JYZ	YitT family
H0G69_RS04460	ENOG4105DG6	mannose-6-phosphate isomerase
H0G69_RS04545	ENOG4105ETZ	PTS System
H0G69_RS04550	ENOG4105F3R	pts system mannose fructose sorbose family iid
H0G69_RS04605	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
H0G69_RS04610	ENOG4108HCJ	Hydrolase
H0G69_RS04615	ENOG4105D1H	recombination factor protein RarA
H0G69_RS04620	ENOG4105CHR	reductase
H0G69_RS04640	ENOG4105CMU	LysR family (Transcriptional regulator
H0G69_RS04645	ENOG4105C6K	Malic enzyme
H0G69_RS04665	ENOG4105F04	LysR family Transcriptional regulator
H0G69_RS04675	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
H0G69_RS04680	ENOG41079KZ	Major Facilitator Superfamily
H0G69_RS04685	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
H0G69_RS04695	ENOG4108UWZ	4-Carboxymuconolactone decarboxylase
H0G69_RS04705	ENOG4105VUF	Transcriptional regulator
H0G69_RS04720	ENOG4105CUB	amino acid
H0G69_RS04735	ENOG4107QHE	Choloylglycine hydrolase
H0G69_RS04755	ENOG4107RCM	Releases the N-terminal proline from various substrates (By similarity)
H0G69_RS04765	ENOG4105KRQ	Addiction module toxin, Txe YoeB family
H0G69_RS04775	ENOG4107RGM	aldo keto reductase
H0G69_RS04780	ENOG4108JYZ	YitT family
H0G69_RS04795	ENOG4108S8M	degv family
H0G69_RS04805	ENOG4108IJ0	Aspartate ammonia-lyase
H0G69_RS04810	ENOG410667J	hydrolase
H0G69_RS04820	ENOG4108XZ3	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division (By similarity)
H0G69_RS04825	ENOG4105HDK	L-asparaginase
H0G69_RS04840	ENOG4105VG1	fes assembly suf system protein
H0G69_RS04850	ENOG4105E90	ABC transporter
H0G69_RS04855	ENOG4108IJ7	Glycine betaine
H0G69_RS04860	ENOG4108Z40	Transcriptional regulator
H0G69_RS04875	ENOG4107QN2	dihydrolipoyl dehydrogenase
H0G69_RS04890	ENOG4105CND	Glycosyl transferase, family 2
H0G69_RS04900	ENOG4108UXE	Protein tyrosine phosphatase
H0G69_RS04905	ENOG4105CSH	Transporter
H0G69_RS04920	ENOG4105EVN	Prephenate dehydrogenase
H0G69_RS04925	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
H0G69_RS04930	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
H0G69_RS04935	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
H0G69_RS04940	ENOG4105EMV	Major Facilitator
H0G69_RS04950	ENOG4105D6E	homoserine dehydrogenase
H0G69_RS04955	ENOG4105D98	threonine synthase
H0G69_RS04965	ENOG4105DG4	malate L-lactate dehydrogenase
H0G69_RS04975	ENOG4105DF9	Lipoate-protein, ligase
H0G69_RS04990	ENOG4105CPP	Dehydrogenase, E1 component
H0G69_RS05005	ENOG41067MG	lrgb family
H0G69_RS05010	ENOG41083D3	Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgB, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses (By similarity)
H0G69_RS05015	ENOG4105DY9	regulatoR
H0G69_RS05020	ENOG4108HRK	Histidine kinase
H0G69_RS05025	ENOG4105EAB	amino acid AbC transporter
H0G69_RS05035	ENOG4105E5Q	amino acid AbC transporter
H0G69_RS05045	ENOG4105DU0	nucleoside hydrolase
H0G69_RS05080	ENOG4105C5I	Dehydrogenase
H0G69_RS05095	ENOG4105C52	Atpase, p-type (Transporting), had superfamily, subfamily ic
H0G69_RS05120	ENOG41083J0	(ABC) transporter
H0G69_RS05125	ENOG4105C4B	ABC transporter, permease
H0G69_RS05130	ENOG410901P	UPF0249 protein
H0G69_RS05135	ENOG4105EVU	fructokinase
H0G69_RS05140	ENOG4105ETE	Transcriptional regulator (LacI family
H0G69_RS05155	ENOG4105C5I	Dehydrogenase
H0G69_RS05160	ENOG4108HMX	isocitrate dehydrogenase (NADP)
H0G69_RS05175	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
H0G69_RS05180	ENOG4108M60	Transcriptional regulator
H0G69_RS05185	ENOG4105C6Z	Gluconate
H0G69_RS05190	ENOG4105CMG	Carbohydrate kinase
H0G69_RS05200	ENOG4107SCQ	Iron-containing alcohol dehydrogenase
H0G69_RS05220	ENOG4105CUB	amino acid
H0G69_RS05230	ENOG4105DWF	phosphomethylpyrimidine kinase
H0G69_RS05240	ENOG4105ETU	transcriptional activator (TenA
H0G69_RS05245	ENOG4105C54	Major Facilitator superfamily
H0G69_RS05255	ENOG4105C5A	transporter
H0G69_RS05265	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
H0G69_RS05270	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
H0G69_RS05280	ENOG4105P4J	Allophanate hydrolase, subunit 1
H0G69_RS05285	ENOG4105CGH	5'-nucleotidase
H0G69_RS05305	ENOG4105CFM	UPF0317 protein
H0G69_RS05315	ENOG4105M6F	mutator MutT protein
H0G69_RS05320	ENOG4105DFD	Na H antiporter
H0G69_RS05325	ENOG4105C26	Dehydrogenase
H0G69_RS05335	ENOG4105DQ6	Transposase
H0G69_RS05350	ENOG4107SET	aldo keto reductase
H0G69_RS05380	ENOG4105D7V	transposase
H0G69_RS05405	ENOG4107TCE	N-acetyltransferase
H0G69_RS05430	ENOG4105E2M	Manganese-dependent inorganic pyrophosphatase
H0G69_RS05440	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
H0G69_RS05450	ENOG4105CHR	reductase
H0G69_RS05460	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
H0G69_RS05465	ENOG4105C79	DNA protecting protein DprA
H0G69_RS05475	ENOG4105C9W	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity (By similarity)
H0G69_RS05485	ENOG4105QZP	Uncharacterized protein conserved in bacteria (DUF2140)
H0G69_RS05505	ENOG4105KMT	branched-chain amino acid
H0G69_RS05510	ENOG4108UMN	azlc family
H0G69_RS05530	ENOG4105CGD	Nad-dependent epimerase dehydratase
H0G69_RS05545	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
H0G69_RS05550	ENOG4108RWP	Major Facilitator Superfamily protein
H0G69_RS05565	ENOG4108NMT	An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon (By similarity)
H0G69_RS05575	ENOG4105D01	(LipO)protein
H0G69_RS05580	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
H0G69_RS05590	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
H0G69_RS05595	ENOG4105CNB	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
H0G69_RS05600	ENOG4105CNB	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
H0G69_RS05605	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
H0G69_RS05630	ENOG4105BZ4	penicillin-binding protein
H0G69_RS05635	ENOG4108UZ3	Transporter
H0G69_RS05650	ENOG4105C5S	asparaginyl-tRNA synthetase
H0G69_RS05660	ENOG4105DVT	helicase
H0G69_RS05665	ENOG4105CRD	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity)
H0G69_RS05690	ENOG4105E90	ABC transporter
H0G69_RS05700	ENOG4105R40	Glycine betaine carnitine choline
H0G69_RS05705	ENOG4105EVU	fructokinase
H0G69_RS05720	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
H0G69_RS05725	ENOG4105MZU	cell filamentation protein
H0G69_RS05880	ENOG4105FA0	parb-like partition protein
H0G69_RS06065	ENOG4107URF	beta-phospho-glucomutase
H0G69_RS06080	ENOG4105ETE	Transcriptional regulator (LacI family
H0G69_RS06120	ENOG4105PUK	Membrane
H0G69_RS06130	ENOG4107URF	beta-phospho-glucomutase
H0G69_RS06135	ENOG4107QK5	Homocysteine s-methyltransferase
H0G69_RS06140	ENOG4108IQI	permease
H0G69_RS06175	ENOG41069HH	4-oxalocrotonate tautomerase
H0G69_RS06200	ENOG4105CZZ	Alpha-N-arabinofuranosidase (EC 3.2.1.55)
H0G69_RS06290	ENOG4105DJ1	Phosphoenolpyruvate Carboxylase
H0G69_RS06305	ENOG4105PY6	Phenolic acid decarboxylase
H0G69_RS06310	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
H0G69_RS06405	ENOG4108FKH	Transglycosylase SLT domain
H0G69_RS06500	ENOG4105DQ6	Transposase
H0G69_RS06635	ENOG4105CUB	amino acid
H0G69_RS06650	ENOG4108BW8	UPF0109 protein
H0G69_RS06665	ENOG4105CZV	ABC transporter
H0G69_RS06675	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
H0G69_RS06685	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
H0G69_RS06690	ENOG4105CDB	Required for chromosome condensation and partitioning (By similarity)
H0G69_RS06700	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
H0G69_RS06710	ENOG4105CB5	ATP-dependent DNA helicase recG
H0G69_RS06730	ENOG4105FJ0	thiamine
H0G69_RS06735	ENOG4105DJV	ribulose-phosphate 3-epimerase
H0G69_RS06745	ENOG4105D9P	serine threonine protein kinase
H0G69_RS06750	ENOG4108ZF3	Phosphatase
H0G69_RS06755	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
H0G69_RS06765	ENOG4105C25	Primosomal protein n'
H0G69_RS06770	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
H0G69_RS06780	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
H0G69_RS06795	ENOG4105EYF	MMPL domain protein
H0G69_RS06810	ENOG4107YZX	Universal stress protein
H0G69_RS06815	ENOG4105CUB	amino acid
H0G69_RS06820	ENOG41067S9	phage shock protein C, PspC
H0G69_RS06840	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
H0G69_RS06845	ENOG4105XBY	Regulates arginine biosynthesis genes (By similarity)
H0G69_RS06850	ENOG4105DX0	Hemolysin A
H0G69_RS06865	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
H0G69_RS06870	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
H0G69_RS06880	ENOG4108ZSR	alkaline shock protein
H0G69_RS06890	ENOG4105DC7	peptidase M24
H0G69_RS06940	ENOG4105X36	(ribosomal) protein
H0G69_RS06975	ENOG4105C5F	glutamine synthetase
H0G69_RS06990	ENOG4105WZW	rhodanese family
H0G69_RS06995	ENOG4105DKQ	ROK family
H0G69_RS07005	ENOG4107ZXI	Rhomboid family
H0G69_RS07010	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
H0G69_RS07025	ENOG4107RF6	penicillin-binding protein
H0G69_RS07035	ENOG4105C59	p-type ATPase
H0G69_RS07060	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
H0G69_RS07080	ENOG4108RWN	rrna methyltransferase
H0G69_RS07085	ENOG41084AG	Acylphosphatase
H0G69_RS07090	ENOG4107XQC	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins (By similarity)
H0G69_RS07095	ENOG4107YDN	peptide deformylase
H0G69_RS07100	ENOG4105C3S	Mate efflux family protein
H0G69_RS07105	ENOG4105GR3	Histidine kinase
H0G69_RS07110	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
H0G69_RS07140	ENOG4108WF2	Metal Dependent Phosphohydrolase
H0G69_RS07145	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
H0G69_RS07150	ENOG410812S	Rna-binding protein
H0G69_RS07155	ENOG4105CQW	ribosome biogenesis GTPase YqeH
H0G69_RS07175	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
H0G69_RS07200	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
H0G69_RS07210	ENOG4105HFZ	Membrane
H0G69_RS07220	ENOG4108VDD	TRNA binding domain protein
H0G69_RS07240	ENOG4107RHR	regulatoR
H0G69_RS07250	ENOG4105CMW	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis (By similarity)
H0G69_RS07260	ENOG4105FCI	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity)
H0G69_RS07280	ENOG4105K59	histidine triad (HIT) protein
H0G69_RS07290	ENOG4107UUG	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity)
H0G69_RS07305	ENOG4105BZ4	penicillin-binding protein
H0G69_RS07315	ENOG4105D0M	Protease HtpX homolog
H0G69_RS07335	ENOG4105EEI	dihydropteroate synthase
H0G69_RS07340	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
H0G69_RS07350	ENOG4105EUJ	GTP cyclohydrolase i
H0G69_RS07355	ENOG4105EUJ	GTP cyclohydrolase i
H0G69_RS07390	ENOG4108DBC	nitroreductase
H0G69_RS07415	ENOG4105CSH	Transporter
H0G69_RS07420	ENOG4105F27	Major Facilitator
H0G69_RS07445	ENOG4105ETE	Transcriptional regulator (LacI family
H0G69_RS07455	ENOG4105ZMH	deoxynucleoside kinase
H0G69_RS07460	ENOG4107X35	defense response to bacterium
H0G69_RS07470	ENOG4107YZX	Universal stress protein
H0G69_RS07475	ENOG4107QSE	Dipeptidase
H0G69_RS07480	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
H0G69_RS07495	ENOG4105C28	cystathionine
H0G69_RS07500	ENOG4105C28	cystathionine
H0G69_RS07510	ENOG4105CDA	abc transporter atp-binding protein
H0G69_RS07515	ENOG4105DRP	amino acid AbC transporter
H0G69_RS07520	ENOG4105E5Q	amino acid AbC transporter
H0G69_RS07525	ENOG4105PF0	Antitoxin component of a toxin-antitoxin (TA) module. Functions as an mRNA interferase antitoxin
H0G69_RS07570	ENOG4105C59	p-type ATPase
H0G69_RS07580	ENOG4105C85	amino acid
H0G69_RS07595	ENOG4107QSE	Dipeptidase
H0G69_RS07600	ENOG4105CSX	c4-dicarboxylate anaerobic carrier
H0G69_RS07610	ENOG4105C8Y	Acetylornithine aminotransferase
H0G69_RS07615	ENOG4105CAS	nag kinase
H0G69_RS07620	ENOG4105C5V	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity)
H0G69_RS07625	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
H0G69_RS07630	ENOG410667J	hydrolase
H0G69_RS07635	ENOG41068KG	domain protein
H0G69_RS07640	ENOG4108S4H	thioesterase Superfamily protein
H0G69_RS07645	ENOG41068KG	domain protein
H0G69_RS07655	ENOG4105DIW	FeS assembly protein SUFB
H0G69_RS07660	ENOG4105JRK	feS assembly protein SufD
H0G69_RS07665	ENOG4105C3K	feS assembly ATPase SufC
H0G69_RS07670	ENOG4108RDD	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine (By similarity)
H0G69_RS07675	ENOG4105CJD	(Anaerobic) ribonucleoside-triphosphate reductase
H0G69_RS07690	ENOG4105D5G	Transposase
H0G69_RS07695	ENOG4108KGH	TRANSCRIPTIONal
H0G69_RS07700	ENOG4105CKK	Glycosyl transferase, family 2
H0G69_RS07705	ENOG4105C02	permease
H0G69_RS07770	ENOG4105D5D	udp-galactopyranose mutase
H0G69_RS07780	ENOG4105K64	Glycosyl transferase, family 2
H0G69_RS07805	ENOG4105DBZ	Dtdp-4-dehydrorhamnose reductase
H0G69_RS07810	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
H0G69_RS07815	ENOG4108URP	Dtdp-4-dehydrorhamnose 3,5-epimerase
H0G69_RS07820	ENOG4108I19	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity)
H0G69_RS07830	ENOG4105D3Q	Sugar transferase
H0G69_RS07840	ENOG4107S2Z	UPF0761 membrane protein
H0G69_RS07845	ENOG4107UZV	polysaccharide biosynthesis
H0G69_RS07850	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
H0G69_RS07860	ENOG4105WH5	Teichoic acid glycosylation protein
H0G69_RS07870	ENOG4105C1J	atp-dependent rna helicase
H0G69_RS07875	ENOG4105EE0	oxidoreductase
H0G69_RS07885	ENOG4108URH	decarboxylase
H0G69_RS07895	ENOG4105D9M	gamma-glutamylcysteine synthetase
H0G69_RS07900	ENOG4105W8X	HesB YadR YfhF-family protein
H0G69_RS07905	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
H0G69_RS07915	ENOG4105CAQ	asparagine synthetase
H0G69_RS07925	ENOG4105CHR	reductase
H0G69_RS08095	ENOG4105W2C	Glycosyl transferase
H0G69_RS08100	ENOG4105BZF	Glycosyl transferase (Group 1
H0G69_RS08105	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
H0G69_RS08110	ENOG4105KRI	phosphocarrier protein (HPr
H0G69_RS08120	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
H0G69_RS08125	ENOG4105FH5	Membrane
H0G69_RS08155	ENOG4105C0A	alcohol dehydrogenase
H0G69_RS08165	ENOG4105ETE	Transcriptional regulator (LacI family
H0G69_RS08245	ENOG4105VUF	Transcriptional regulator
H0G69_RS08250	ENOG4108JQ1	Dehydrogenase
H0G69_RS08260	ENOG4108UYN	gCN5-related N-acetyltransferase
H0G69_RS08280	ENOG4105VEQ	Cold shock protein
H0G69_RS08305	ENOG4105DZR	Type I site-specific deoxyribonuclease
H0G69_RS08320	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
H0G69_RS08330	ENOG4105CVR	type I restriction-modification system
H0G69_RS08370	ENOG4105C2M	dna polymerase I
H0G69_RS08425	ENOG4105CAR	Terminase, large subunit
H0G69_RS08490	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
H0G69_RS08495	ENOG4105CBD	Diacylglycerol kinase
H0G69_RS08510	ENOG4105VB5	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
H0G69_RS08525	ENOG4105C4R	Atp-dependent dna helicase
H0G69_RS08530	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
H0G69_RS08540	ENOG4108ZW7	flagellar rod assembly protein muramidase flgj
H0G69_RS08545	ENOG4108UJD	30S ribosomal protein S9
H0G69_RS08560	ENOG4105EK6	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates (By similarity)
H0G69_RS08565	ENOG4108JJB	ABC transporter
H0G69_RS08570	ENOG4108JJB	ABC transporter
H0G69_RS08610	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
H0G69_RS08665	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
H0G69_RS08680	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
H0G69_RS08755	ENOG4108Q5F	Tetr family transcriptional regulator
H0G69_RS08760	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
H0G69_RS08765	ENOG4105KEX	transcriptional regulator, ctsr
H0G69_RS08785	ENOG4105CCI	Myosin-Cross-Reactive Antigen
H0G69_RS08820	ENOG4105C59	p-type ATPase
H0G69_RS08825	ENOG4107ZYR	domain protein
H0G69_RS08845	ENOG4105ZMH	deoxynucleoside kinase
H0G69_RS08850	ENOG4108IQI	permease
H0G69_RS08855	ENOG4108IQI	permease
H0G69_RS08890	ENOG4105PGM	cation diffusion facilitator family transporter
H0G69_RS08895	ENOG4108QXE	glycerophosphoryl diester phosphodiesterase
H0G69_RS08945	ENOG4105D5G	Transposase
H0G69_RS08965	ENOG4105EMS	pseudouridine synthase
H0G69_RS08980	ENOG4105CUB	amino acid
H0G69_RS08985	ENOG4108JPW	Aminotransferase
H0G69_RS09015	ENOG4108K6F	triphosphoribosyl-dephospho-CoA synthase
H0G69_RS09030	ENOG4105XGS	Covalent carrier of the coenzyme of citrate lyase (By similarity)
H0G69_RS09055	ENOG4107QPK	)-transporter
H0G69_RS09060	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
H0G69_RS09080	ENOG4105C5Y	PTS System
H0G69_RS09095	ENOG4108HKT	sucrose-6-phosphate hydrolase
H0G69_RS09115	ENOG4105CSR	polyphosphate kinase 2
H0G69_RS09155	ENOG4108UZ3	Transporter
H0G69_RS09160	ENOG4107UA9	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) (By similarity)
H0G69_RS09180	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
H0G69_RS09185	ENOG4105C19	ABC transporter
H0G69_RS09225	ENOG4105US7	Histidine kinase
H0G69_RS09235	ENOG4105E0M	Sulfatase
H0G69_RS09240	ENOG4105EEM	helicase
H0G69_RS09245	ENOG4105DQR	SNARE associated Golgi
H0G69_RS09255	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
H0G69_RS09265	ENOG4105ENN	converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity)
H0G69_RS09285	ENOG4105N80	Ferric uptake regulator, Fur family
H0G69_RS09290	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
H0G69_RS09300	ENOG4105CUB	amino acid
H0G69_RS09310	ENOG4105D38	putrescine abc transporter
H0G69_RS09315	ENOG4105E0C	molybdate abc transporter
H0G69_RS09320	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
H0G69_RS09330	ENOG4105CHR	reductase
H0G69_RS09340	ENOG4105GYP	Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline (By similarity)
H0G69_RS09345	ENOG4107T66	Releases the N-terminal proline from various substrates (By similarity)
H0G69_RS09350	ENOG4105KVH	Transcriptional regulator
H0G69_RS09360	ENOG4107XGZ	Hydrolase
H0G69_RS09365	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
H0G69_RS09395	ENOG4105E98	transcriptional regulator DeoR family
H0G69_RS09405	ENOG41064BZ	L-xylulose 5-phosphate 3-epimerase
H0G69_RS09410	ENOG4105CMG	Carbohydrate kinase
H0G69_RS09430	ENOG4105DT3	PTS system, galactitol-specific IIc component
H0G69_RS09440	ENOG4105ETE	Transcriptional regulator (LacI family
H0G69_RS09450	ENOG41064BZ	L-xylulose 5-phosphate 3-epimerase
H0G69_RS09455	ENOG4105ETE	Transcriptional regulator (LacI family
H0G69_RS09460	ENOG4108KA0	Inherit from COG: Phosphoesterase, DHHA1
H0G69_RS09475	ENOG4105C5H	ABC transporter
H0G69_RS09480	ENOG4108V3G	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity)
H0G69_RS09490	ENOG4108UNV	SUF system FeS assembly protein, NifU family
H0G69_RS09495	ENOG4105C9B	Cysteine desulfurase
H0G69_RS09505	ENOG4105C7J	ABC transporter, permease
H0G69_RS09510	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
H0G69_RS09520	ENOG4105KVH	Transcriptional regulator
H0G69_RS09525	ENOG4105C3S	Mate efflux family protein
H0G69_RS09530	ENOG4105BZU	Histidine kinase
H0G69_RS09535	ENOG4105EDR	glucose galactose transporter
H0G69_RS09550	ENOG4105K63	Thioredoxin
H0G69_RS09555	ENOG4107TS3	membrane protein, TerC
H0G69_RS09560	ENOG4105EMS	pseudouridine synthase
H0G69_RS09575	ENOG4105DZW	Dipeptidase
H0G69_RS09580	ENOG4105DKJ	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
H0G69_RS09590	ENOG4105E0M	Sulfatase
H0G69_RS09595	ENOG4108RCM	Nitroreductase
H0G69_RS09600	ENOG4105K8R	UPF0145 protein
H0G69_RS09615	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
H0G69_RS09625	ENOG4108JJB	ABC transporter
H0G69_RS09640	ENOG4105ETE	Transcriptional regulator (LacI family
H0G69_RS09660	ENOG4105D7K	pfkb domain protein
H0G69_RS09705	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
H0G69_RS09710	ENOG4105IJJ	transcriptional regulator, crp fnr family
H0G69_RS09720	ENOG4108HCJ	Hydrolase
H0G69_RS09725	ENOG4108TZY	GntR Family Transcriptional Regulator
H0G69_RS09730	ENOG4108Z66	YbaK ebsC protein
H0G69_RS09740	ENOG4105DZW	Dipeptidase
H0G69_RS09775	ENOG4105CV8	reductase
H0G69_RS09785	ENOG4105DJ2	Major Facilitator Superfamily
H0G69_RS09795	ENOG4105C7Q	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity)
H0G69_RS09845	ENOG4107YZX	Universal stress protein
H0G69_RS09850	ENOG4105EW9	transcriptional regulator AsnC family
H0G69_RS09855	ENOG4105DPN	Oligoendopeptidase f
H0G69_RS09865	ENOG4107RBJ	symporter
H0G69_RS09885	ENOG4105CQ4	Transcriptional regulator
H0G69_RS09890	ENOG4105CKN	UDP-glucose-hexose-1-phosphate uridylyltransferase
H0G69_RS09905	ENOG4105M2Z	protein tyrosine serine phosphatase
H0G69_RS09925	ENOG4105KP9	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
H0G69_RS09930	ENOG4108UVJ	appr-1-p processing domain protein
H0G69_RS09935	ENOG4105C9K	Endothelin-converting enzyme 1
H0G69_RS09955	ENOG4108VX5	3-methyladenine DNA glycosylase
H0G69_RS09960	ENOG4105K78	MarR family Transcriptional regulator
H0G69_RS10000	ENOG4105ETE	Transcriptional regulator (LacI family
H0G69_RS10030	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
H0G69_RS10035	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
H0G69_RS10055	ENOG4105C56	H( )-stimulated, divalent metal cation uptake system (By similarity)
H0G69_RS10065	ENOG4105C22	threonyL-tRNA synthetase
H0G69_RS10070	ENOG4105DZW	Dipeptidase
H0G69_RS10080	ENOG4105C3F	Signal peptidase i
H0G69_RS10085	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
H0G69_RS10090	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
H0G69_RS10095	ENOG4105CAQ	asparagine synthetase
H0G69_RS10105	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
H0G69_RS10110	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
H0G69_RS10120	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
H0G69_RS10145	ENOG4105D5G	Transposase
H0G69_RS10155	ENOG4108I5U	Uridine phosphorylase
H0G69_RS10160	ENOG4107XDY	Nicotinamide Mononucleotide Transporter
H0G69_RS10185	ENOG4105DQ6	Transposase
H0G69_RS10210	ENOG4106F1P	AAA ATPase, central domain protein
H0G69_RS10265	ENOG4105D5G	Transposase
H0G69_RS10275	ENOG4105DT3	PTS system, galactitol-specific IIc component
H0G69_RS10290	ENOG4105ETD	TRANSCRIPTIONal
H0G69_RS10350	ENOG4105ETD	TRANSCRIPTIONal
H0G69_RS10365	ENOG4105DT3	PTS system, galactitol-specific IIc component
H0G69_RS10375	ENOG4105D5G	Transposase
H0G69_RS10430	ENOG4106F1P	AAA ATPase, central domain protein
H0G69_RS10450	ENOG4105DQ6	Transposase
H0G69_RS10475	ENOG4107XDY	Nicotinamide Mononucleotide Transporter
H0G69_RS10490	ENOG4105D5G	Transposase
H0G69_RS10625	ENOG4108FKH	Transglycosylase SLT domain