locus-tag	class	description
LCA12A_RS00010	COG0592	DNA-directed DNA polymerase activity
LCA12A_RS00015	COG2501	S4 domain
LCA12A_RS00025	COG0187	DNA topoisomerase II activity
LCA12A_RS00035	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
LCA12A_RS00050	COG0629	single-stranded DNA binding
LCA12A_RS00060	COG1271	oxidase subunit
LCA12A_RS00120	COG3942	CHAP domain
LCA12A_RS00140	COG0561	phosphatase activity
LCA12A_RS00160	COG3409	Peptidoglycan-binding domain 1 protein
LCA12A_RS00275	COG0800	Aldolase
LCA12A_RS00305	COG2814	Major facilitator Superfamily
LCA12A_RS00315	COG1033	growth of symbiont in host cell
LCA12A_RS00315	COG2409	Drug exporters of the RND superfamily
LCA12A_RS00320	COG1309	transcriptional regulator
LCA12A_RS00335	COG1732	Glycine betaine
LCA12A_RS00370	COG2217	Heavy metal translocating P-type atpase
LCA12A_RS00375	COG2217	Heavy metal translocating P-type atpase
LCA12A_RS00385	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
LCA12A_RS00395	COG0577	efflux transmembrane transporter activity
LCA12A_RS00395	COG1136	(ABC) transporter
LCA12A_RS00405	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LCA12A_RS00405	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
LCA12A_RS00405	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LCA12A_RS00410	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LCA12A_RS00410	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
LCA12A_RS00410	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LCA12A_RS00415	COG0383	alpha-mannosidase activity
LCA12A_RS00425	COG2723	6-phospho-beta-galactosidase activity
LCA12A_RS00430	COG1940	carbohydrate kinase activity
LCA12A_RS00435	COG0159	tryptophan synthase activity
LCA12A_RS00445	COG0135	phosphoribosylanthranilate isomerase activity
LCA12A_RS00465	COG2814	Major facilitator Superfamily
LCA12A_RS00490	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
LCA12A_RS00510	COG0019	diaminopimelate decarboxylase activity
LCA12A_RS00515	COG0527	aspartate kinase activity
LCA12A_RS00525	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
LCA12A_RS00570	COG0305	Participates in initiation and elongation during chromosome replication
LCA12A_RS00585	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
LCA12A_RS00590	COG1737	Transcriptional regulator
LCA12A_RS00595	COG1309	transcriptional regulator
LCA12A_RS00600	COG1136	(ABC) transporter
LCA12A_RS00600	COG0577	efflux transmembrane transporter activity
LCA12A_RS00620	COG2217	Heavy metal translocating P-type atpase
LCA12A_RS00625	COG0640	Transcriptional regulator
LCA12A_RS00630	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
LCA12A_RS00635	COG0583	DNA-binding transcription factor activity
LCA12A_RS00650	COG3620	sequence-specific DNA binding
LCA12A_RS00660	COG1131	(ABC) transporter
LCA12A_RS00670	COG1328	CTP reductase activity
LCA12A_RS00735	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
LCA12A_RS00770	COG2252	PERMEase
LCA12A_RS00785	COG1116	anion transmembrane transporter activity
LCA12A_RS00790	COG4521	taurine ABC transporter
LCA12A_RS00795	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
LCA12A_RS00800	COG0446	pyridine nucleotide-disulphide oxidoreductase
LCA12A_RS00805	COG2391	methyltransferase activity
LCA12A_RS00820	COG0346	lactoylglutathione lyase activity
LCA12A_RS00880	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
LCA12A_RS00925	COG1511	domain protein
LCA12A_RS00935	COG0477	Major facilitator Superfamily
LCA12A_RS00945	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
LCA12A_RS00950	COG4166	transmembrane transport
LCA12A_RS00980	COG1396	sequence-specific DNA binding
LCA12A_RS00990	COG0446	pyridine nucleotide-disulphide oxidoreductase
LCA12A_RS01030	COG0716	FMN binding
LCA12A_RS01045	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LCA12A_RS01055	COG2261	transglycosylase associated protein
LCA12A_RS01070	COG1302	Protein conserved in bacteria
LCA12A_RS01100	COG3442	glutamine amidotransferase
LCA12A_RS01120	COG1192	Involved in chromosome partitioning
LCA12A_RS01125	COG1475	DNA binding
LCA12A_RS01130	COG4481	Protein conserved in bacteria
LCA12A_RS01135	COG0012	GTP binding
LCA12A_RS01145	COG0517	IMP dehydrogenase activity
LCA12A_RS01145	COG0516	GMP reductase activity
LCA12A_RS01165	COG1686	Belongs to the peptidase S11 family
LCA12A_RS01170	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
LCA12A_RS01180	COG1794	racemase activity, acting on amino acids and derivatives
LCA12A_RS01185	COG0656	L-ascorbic acid biosynthetic process
LCA12A_RS01190	COG1349	DNA-binding transcription factor activity
LCA12A_RS01195	COG2814	Major facilitator Superfamily
LCA12A_RS01205	COG3718	enzyme involved in inositol metabolism
LCA12A_RS01210	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LCA12A_RS01215	COG3962	Belongs to the TPP enzyme family
LCA12A_RS01220	COG0673	inositol 2-dehydrogenase activity
LCA12A_RS01225	COG0673	inositol 2-dehydrogenase activity
LCA12A_RS01235	COG0191	fructose-bisphosphate aldolase activity
LCA12A_RS01240	COG1942	4-Oxalocrotonate Tautomerase
LCA12A_RS01245	COG1737	Transcriptional regulator
LCA12A_RS01250	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
LCA12A_RS01260	COG2610	gluconate transmembrane transporter activity
LCA12A_RS01270	COG1121	(ABC) transporter
LCA12A_RS01285	COG2084	Dehydrogenase
LCA12A_RS01290	COG1164	Oligoendopeptidase f
LCA12A_RS01295	COG1316	TRANSCRIPTIONal
LCA12A_RS01300	COG1114	Component of the transport system for branched-chain amino acids
LCA12A_RS01315	COG1216	Glycosyl transferase, family 2
LCA12A_RS01340	COG0488	(ABC) transporter
LCA12A_RS01375	COG3118	belongs to the thioredoxin family
LCA12A_RS01395	COG0683	leucine binding
LCA12A_RS01425	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
LCA12A_RS01435	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
LCA12A_RS01440	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
LCA12A_RS01465	COG2723	6-phospho-beta-galactosidase activity
LCA12A_RS01470	COG0446	pyridine nucleotide-disulphide oxidoreductase
LCA12A_RS01490	COG2182	Extracellular solute-binding protein
LCA12A_RS01500	COG3525	Glycosyl hydrolase, family 20, catalytic domain
LCA12A_RS01500	COG3064	Membrane
LCA12A_RS01500	COG3583	domain protein
LCA12A_RS01505	COG1482	cell wall glycoprotein biosynthetic process
LCA12A_RS01510	COG2188	Transcriptional regulator
LCA12A_RS01515	COG2222	sugar isomerase
LCA12A_RS01520	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
LCA12A_RS01530	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LCA12A_RS01535	COG3715	PTS system
LCA12A_RS01540	COG3716	PTS system mannose fructose sorbose family IID component
LCA12A_RS01545	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LCA12A_RS01545	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
LCA12A_RS01560	COG3775	system Galactitol-specific IIC component
LCA12A_RS01570	COG3414	Phosphotransferase system galactitol-specific IIB component
LCA12A_RS01585	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
LCA12A_RS01590	COG0006	proline dipeptidase activity
LCA12A_RS01595	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
LCA12A_RS01600	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
LCA12A_RS01605	COG1447	Phosphotransferase system cellobiose-specific component IIA
LCA12A_RS01610	COG1363	Peptidase, m42
LCA12A_RS01620	COG2195	Cleaves the N-terminal amino acid of tripeptides
LCA12A_RS01625	COG4166	transmembrane transport
LCA12A_RS01645	COG1129	ABC transporter
LCA12A_RS01655	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
LCA12A_RS01675	COG0351	phosphomethylpyrimidine kinase
LCA12A_RS01680	COG0531	amino acid
LCA12A_RS01700	COG1609	Transcriptional regulator
LCA12A_RS01715	COG1172	Belongs to the binding-protein-dependent transport system permease family
LCA12A_RS01720	COG1879	ABC-type sugar transport system periplasmic component
LCA12A_RS01745	COG1174	glycine betaine transport
LCA12A_RS01750	COG1125	glycine betaine transport
LCA12A_RS01755	COG3321	synthase
LCA12A_RS01755	COG0604	alcohol dehydrogenase
LCA12A_RS01760	COG2814	Major facilitator Superfamily
LCA12A_RS01790	COG1053	succinate dehydrogenase
LCA12A_RS01795	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
LCA12A_RS01825	COG1378	Sugar-specific transcriptional regulator TrmB
LCA12A_RS01840	COG2267	carboxylic ester hydrolase activity
LCA12A_RS01905	COG0191	fructose-bisphosphate aldolase activity
LCA12A_RS01920	COG0583	DNA-binding transcription factor activity
LCA12A_RS01935	COG1122	ATPase activity
LCA12A_RS01945	COG3250	beta-galactosidase activity
LCA12A_RS01950	COG0531	amino acid
LCA12A_RS01955	COG0833	amino acid
LCA12A_RS01960	COG2207	Transcriptional regulator
LCA12A_RS02010	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
LCA12A_RS02015	COG1349	DNA-binding transcription factor activity
LCA12A_RS02020	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
LCA12A_RS02025	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
LCA12A_RS02030	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
LCA12A_RS02030	COG2213	PTS system mannitol-specific
LCA12A_RS02035	COG0246	Mannitol dehydrogenase
LCA12A_RS02045	COG1126	abc transporter atp-binding protein
LCA12A_RS02050	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LCA12A_RS02055	COG0765	amino acid transport
LCA12A_RS02060	COG0765	amino acid transport
LCA12A_RS02065	COG0477	Major facilitator Superfamily
LCA12A_RS02085	COG4221	oxidoreductase activity
LCA12A_RS02110	COG0446	pyridine nucleotide-disulphide oxidoreductase
LCA12A_RS02115	COG0561	phosphatase activity
LCA12A_RS02125	COG1609	Transcriptional regulator
LCA12A_RS02130	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LCA12A_RS02140	COG3716	PTS system mannose fructose sorbose family IID component
LCA12A_RS02155	COG0366	Alpha amylase catalytic
LCA12A_RS02160	COG1132	(ABC) transporter
LCA12A_RS02165	COG1132	(ABC) transporter
LCA12A_RS02185	COG1464	Belongs to the NlpA lipoprotein family
LCA12A_RS02215	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
LCA12A_RS02220	COG1461	Dihydroxyacetone kinase
LCA12A_RS02225	COG2376	Dihydroxyacetone kinase
LCA12A_RS02260	COG2814	Major facilitator Superfamily
LCA12A_RS02280	COG0028	Belongs to the TPP enzyme family
LCA12A_RS02295	COG2226	methyltransferase
LCA12A_RS02300	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
LCA12A_RS02305	COG0174	glutamine synthetase
LCA12A_RS02320	COG0789	Transcriptional regulator
LCA12A_RS02325	COG0656	L-ascorbic acid biosynthetic process
LCA12A_RS02335	COG1733	regulation of RNA biosynthetic process
LCA12A_RS02345	COG2723	6-phospho-beta-galactosidase activity
LCA12A_RS02350	COG1447	Phosphotransferase system cellobiose-specific component IIA
LCA12A_RS02355	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
LCA12A_RS02360	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
LCA12A_RS02370	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
LCA12A_RS02395	COG1131	(ABC) transporter
LCA12A_RS02425	COG0308	aminopeptidase N
LCA12A_RS02430	COG0531	amino acid
LCA12A_RS02450	COG1028	Short-chain dehydrogenase reductase Sdr
LCA12A_RS02460	COG2271	Major facilitator Superfamily
LCA12A_RS02465	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
LCA12A_RS02470	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
LCA12A_RS02475	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
LCA12A_RS02490	COG0626	cystathionine gamma-synthase activity
LCA12A_RS02495	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LCA12A_RS02500	COG0765	amino acid transport
LCA12A_RS02510	COG1114	Component of the transport system for branched-chain amino acids
LCA12A_RS02565	COG0697	spore germination
LCA12A_RS02575	COG1131	(ABC) transporter
LCA12A_RS02590	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
LCA12A_RS02595	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
LCA12A_RS02600	COG1132	(ABC) transporter
LCA12A_RS02605	COG1132	(ABC) transporter
LCA12A_RS02610	COG2223	nitrite transmembrane transporter activity
LCA12A_RS02615	COG2188	Transcriptional regulator
LCA12A_RS02620	COG0366	Alpha amylase catalytic
LCA12A_RS02625	COG1263	PTS System
LCA12A_RS02625	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LCA12A_RS02625	COG2190	(PTS) system
LCA12A_RS02635	COG0531	amino acid
LCA12A_RS02640	COG0039	L-malate dehydrogenase activity
LCA12A_RS02645	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
LCA12A_RS02650	COG1278	Cold shock
LCA12A_RS02665	COG0488	(ABC) transporter
LCA12A_RS02670	COG0702	epimerase
LCA12A_RS02675	COG0656	L-ascorbic acid biosynthetic process
LCA12A_RS02680	COG1113	amino acid transport
LCA12A_RS02690	COG0025	NhaP-type Na H and K H
LCA12A_RS02710	COG1131	(ABC) transporter
LCA12A_RS02730	COG0604	alcohol dehydrogenase
LCA12A_RS02735	COG0004	ammonium transporteR
LCA12A_RS02745	COG1285	pathogenesis
LCA12A_RS02775	COG1131	(ABC) transporter
LCA12A_RS02790	COG0488	(ABC) transporter
LCA12A_RS02795	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
LCA12A_RS02800	COG1573	uracil-dna glycosylase
LCA12A_RS02805	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
LCA12A_RS02810	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
LCA12A_RS02815	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
LCA12A_RS02820	COG1215	transferase activity, transferring glycosyl groups
LCA12A_RS02830	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
LCA12A_RS02835	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
LCA12A_RS02840	COG1609	Transcriptional regulator
LCA12A_RS02845	COG2017	converts alpha-aldose to the beta-anomer
LCA12A_RS02890	COG3684	Belongs to the aldolase LacD family
LCA12A_RS02905	COG1349	DNA-binding transcription factor activity
LCA12A_RS02920	COG0419	ATPase involved in DNA repair
LCA12A_RS02940	COG1194	a g-specific adenine glycosylase
LCA12A_RS02950	COG2249	NAD(P)H dehydrogenase (quinone) activity
LCA12A_RS02970	COG0351	phosphomethylpyrimidine kinase
LCA12A_RS02985	COG2910	NAD(P)H-binding
LCA12A_RS02990	COG1472	Belongs to the glycosyl hydrolase 3 family
LCA12A_RS03005	COG4120	Belongs to the binding-protein-dependent transport system permease family
LCA12A_RS03015	COG0604	alcohol dehydrogenase
LCA12A_RS03025	COG0463	Glycosyl transferase, family 2
LCA12A_RS03030	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
LCA12A_RS03040	COG0745	RESPONSE REGULATOR receiver
LCA12A_RS03045	COG5002	protein histidine kinase activity
LCA12A_RS03055	COG2508	Transcriptional regulator
LCA12A_RS03060	COG1028	Short-chain dehydrogenase reductase Sdr
LCA12A_RS03070	COG0778	Nitroreductase
LCA12A_RS03075	COG1304	FMN binding
LCA12A_RS03115	COG0604	alcohol dehydrogenase
LCA12A_RS03130	COG0628	permease
LCA12A_RS03155	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
LCA12A_RS03170	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
LCA12A_RS03175	COG3189	MarR family transcriptional regulator
LCA12A_RS03200	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
LCA12A_RS03215	COG1132	(ABC) transporter
LCA12A_RS03230	COG0300	oxidoreductase activity
LCA12A_RS03235	COG0105	UTP biosynthetic process
LCA12A_RS03240	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
LCA12A_RS03245	COG2267	carboxylic ester hydrolase activity
LCA12A_RS03275	COG2267	carboxylic ester hydrolase activity
LCA12A_RS03310	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
LCA12A_RS03340	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
LCA12A_RS03345	COG0343	queuine tRNA-ribosyltransferase activity
LCA12A_RS03350	COG1862	Preprotein translocase
LCA12A_RS03355	COG1454	alcohol dehydrogenase
LCA12A_RS03355	COG1012	belongs to the aldehyde dehydrogenase family
LCA12A_RS03365	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
LCA12A_RS03370	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
LCA12A_RS03375	COG4109	DRTGG domain
LCA12A_RS03380	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
LCA12A_RS03385	COG0513	Belongs to the DEAD box helicase family
LCA12A_RS03435	COG3118	belongs to the thioredoxin family
LCA12A_RS03450	COG1696	Membrane protein involved in D-alanine export
LCA12A_RS03460	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
LCA12A_RS03465	COG1719	4-vinyl reductase, 4VR
LCA12A_RS03470	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
LCA12A_RS03480	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
LCA12A_RS03495	COG0668	transmembrane transport
LCA12A_RS03510	COG1827	regulation of RNA biosynthetic process
LCA12A_RS03515	COG0006	proline dipeptidase activity
LCA12A_RS03520	COG1609	Transcriptional regulator
LCA12A_RS03525	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
LCA12A_RS03530	COG1011	Hydrolase
LCA12A_RS03570	COG0737	Belongs to the 5'-nucleotidase family
LCA12A_RS03575	COG4470	Protein conserved in bacteria
LCA12A_RS03580	COG0647	UMP catabolic process
LCA12A_RS03590	COG0586	Pfam SNARE associated Golgi protein
LCA12A_RS03595	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
LCA12A_RS03610	COG1098	S1 RNA binding domain
LCA12A_RS03760	COG0531	amino acid
LCA12A_RS03765	COG0438	transferase activity, transferring glycosyl groups
LCA12A_RS03770	COG0438	transferase activity, transferring glycosyl groups
LCA12A_RS03785	COG0436	Aminotransferase
LCA12A_RS03795	COG1368	sulfuric ester hydrolase activity
LCA12A_RS03800	COG0735	belongs to the Fur family
LCA12A_RS03845	COG0477	Major facilitator Superfamily
LCA12A_RS03855	COG2814	Major facilitator Superfamily
LCA12A_RS03865	COG0671	phosphoesterase, PA-phosphatase related
LCA12A_RS03875	COG2244	polysaccharide biosynthetic process
LCA12A_RS03880	COG1187	pseudouridine synthase activity
LCA12A_RS03890	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
LCA12A_RS03910	COG0438	transferase activity, transferring glycosyl groups
LCA12A_RS03915	COG0386	Belongs to the glutathione peroxidase family
LCA12A_RS03920	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
LCA12A_RS03930	COG3830	Belongs to the UPF0237 family
LCA12A_RS03955	COG2357	RelA SpoT domain protein
LCA12A_RS03965	COG0564	pseudouridine synthase activity
LCA12A_RS03975	COG3142	Participates in the control of copper homeostasis
LCA12A_RS03985	COG2706	6-phosphogluconolactonase activity
LCA12A_RS03995	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
LCA12A_RS04010	COG2226	methyltransferase
LCA12A_RS04015	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
LCA12A_RS04025	COG1674	ftsk spoiiie
LCA12A_RS04030	COG0612	Peptidase, M16
LCA12A_RS04035	COG0612	Peptidase, M16
LCA12A_RS04040	COG1028	Short-chain dehydrogenase reductase Sdr
LCA12A_RS04045	COG1426	Protein conserved in bacteria
LCA12A_RS04050	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
LCA12A_RS04060	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
LCA12A_RS04070	COG1739	Uncharacterized protein family UPF0029
LCA12A_RS04075	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
LCA12A_RS04095	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
LCA12A_RS04100	COG2884	Cell division ATP-binding protein ftsE
LCA12A_RS04105	COG2177	Part of the ABC transporter FtsEX involved in
LCA12A_RS04115	COG0745	RESPONSE REGULATOR receiver
LCA12A_RS04120	COG5002	protein histidine kinase activity
LCA12A_RS04130	COG0573	inorganic phosphate transmembrane transporter activity
LCA12A_RS04135	COG0581	inorganic phosphate transmembrane transporter activity
LCA12A_RS04140	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
LCA12A_RS04145	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
LCA12A_RS04150	COG0704	Plays a role in the regulation of phosphate uptake
LCA12A_RS04165	COG1950	PFAM Membrane protein of
LCA12A_RS04175	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
LCA12A_RS04185	COG0492	ferredoxin-NADP+ reductase activity
LCA12A_RS04190	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
LCA12A_RS04195	COG0745	RESPONSE REGULATOR receiver
LCA12A_RS04200	COG2205	protein histidine kinase activity
LCA12A_RS04205	COG1136	(ABC) transporter
LCA12A_RS04225	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
LCA12A_RS04240	COG0391	Required for morphogenesis under gluconeogenic growth conditions
LCA12A_RS04250	COG1846	Transcriptional regulator
LCA12A_RS04275	COG2390	Transcriptional regulator
LCA12A_RS04315	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
LCA12A_RS04325	COG0557	exoribonuclease II activity
LCA12A_RS04335	COG1609	Transcriptional regulator
LCA12A_RS04340	COG0366	Alpha amylase catalytic
LCA12A_RS04355	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
LCA12A_RS04360	COG3842	ATPase activity
LCA12A_RS04375	COG1175	transmembrane transport
LCA12A_RS04380	COG3833	ABC-type maltose transport systems, permease component
LCA12A_RS04405	COG0395	ABC-type sugar transport system, permease component
LCA12A_RS04410	COG1175	transmembrane transport
LCA12A_RS04430	COG0561	phosphatase activity
LCA12A_RS04440	COG0280	phosphate acetyltransferase
LCA12A_RS04445	COG0802	atpase or kinase
LCA12A_RS04455	COG4152	abc transporter atp-binding protein
LCA12A_RS04460	COG1668	transmembrane transport
LCA12A_RS04470	COG0708	Exodeoxyribonuclease III
LCA12A_RS04485	COG1396	sequence-specific DNA binding
LCA12A_RS04485	COG3800	Transcriptional regulator
LCA12A_RS04495	COG1176	ABC-type spermidine putrescine transport system, permease component I
LCA12A_RS04500	COG1177	transmembrane transport
LCA12A_RS04505	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
LCA12A_RS04520	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
LCA12A_RS04525	COG1309	transcriptional regulator
LCA12A_RS04555	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
LCA12A_RS04575	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
LCA12A_RS04580	COG1459	type II secretion system
LCA12A_RS04605	COG0827	DNA restriction-modification system
LCA12A_RS04615	COG1113	amino acid transport
LCA12A_RS04660	COG0745	RESPONSE REGULATOR receiver
LCA12A_RS04665	COG5002	protein histidine kinase activity
LCA12A_RS04665	COG3850	Histidine kinase
LCA12A_RS04695	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
LCA12A_RS04755	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
LCA12A_RS04765	COG2814	Major facilitator Superfamily
LCA12A_RS04770	COG0561	phosphatase activity
LCA12A_RS04775	COG2326	polyphosphate kinase activity
LCA12A_RS04780	COG3590	peptidase
LCA12A_RS04785	COG2814	Major facilitator Superfamily
LCA12A_RS04825	COG0673	inositol 2-dehydrogenase activity
LCA12A_RS04835	COG1447	Phosphotransferase system cellobiose-specific component IIA
LCA12A_RS04855	COG0514	ATP-dependent DNA helicase (RecQ)
LCA12A_RS04860	COG2309	aminopeptidase activity
LCA12A_RS04875	COG1295	ribonuclease BN
LCA12A_RS04880	COG0716	FMN binding
LCA12A_RS04885	COG0024	Methionine aminopeptidase
LCA12A_RS04890	COG0463	Glycosyl transferase, family 2
LCA12A_RS04910	COG1210	Utp--glucose-1-phosphate uridylyltransferase
LCA12A_RS04935	COG4485	Bacterial membrane protein, YfhO
LCA12A_RS04945	COG0463	Glycosyl transferase, family 2
LCA12A_RS04955	COG4129	membrane
LCA12A_RS04960	COG1278	Cold shock
LCA12A_RS04970	COG1705	Flagellar rod assembly protein muramidase FlgJ
LCA12A_RS04985	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
LCA12A_RS04990	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
LCA12A_RS05005	COG1368	sulfuric ester hydrolase activity
LCA12A_RS05015	COG4975	Glucose uptake
LCA12A_RS05025	COG0582	viral genome integration into host DNA
LCA12A_RS05040	COG1268	BioY protein
LCA12A_RS05075	COG1396	sequence-specific DNA binding
LCA12A_RS05130	COG0629	single-stranded DNA binding
LCA12A_RS05370	COG0590	tRNA wobble adenosine to inosine editing
LCA12A_RS05395	COG2814	Major facilitator Superfamily
LCA12A_RS05400	COG3548	integral membrane protein
LCA12A_RS05450	COG2514	catechol 2,3-dioxygenase activity
LCA12A_RS05460	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
LCA12A_RS05465	COG1435	thymidine kinase activity
LCA12A_RS05475	COG2890	protein-(glutamine-N5) methyltransferase activity
LCA12A_RS05480	COG0009	L-threonylcarbamoyladenylate synthase
LCA12A_RS05495	COG0356	it plays a direct role in the translocation of protons across the membrane
LCA12A_RS05540	COG1077	Cell shape determining protein MreB Mrl
LCA12A_RS05560	COG0772	Belongs to the SEDS family
LCA12A_RS05565	COG0509	glycine decarboxylation via glycine cleavage system
LCA12A_RS05570	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
LCA12A_RS05575	COG1464	Belongs to the NlpA lipoprotein family
LCA12A_RS05580	COG1464	Belongs to the NlpA lipoprotein family
LCA12A_RS05590	COG2011	ABC-type metal ion transport system permease component
LCA12A_RS05600	COG0719	Fe-S assembly protein
LCA12A_RS05605	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
LCA12A_RS05610	COG0822	iron-sulfur transferase activity
LCA12A_RS05615	COG0719	Fe-S assembly protein
LCA12A_RS05645	COG0589	response to stress
LCA12A_RS05655	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
LCA12A_RS05660	COG2918	glutathione biosynthetic process
LCA12A_RS05660	COG0189	ligase activity
LCA12A_RS05665	COG5506	Protein of unknown function (DUF1694)
LCA12A_RS05675	COG1760	l-serine dehydratase
LCA12A_RS05680	COG1760	l-serine dehydratase
LCA12A_RS05695	COG1028	Short-chain dehydrogenase reductase Sdr
LCA12A_RS05705	COG1428	Deoxynucleoside kinase
LCA12A_RS05725	COG4166	transmembrane transport
LCA12A_RS05730	COG2205	protein histidine kinase activity
LCA12A_RS05735	COG0745	RESPONSE REGULATOR receiver
LCA12A_RS05750	COG0583	DNA-binding transcription factor activity
LCA12A_RS05785	COG0454	-acetyltransferase
LCA12A_RS05800	COG1307	EDD domain protein, DegV family
LCA12A_RS05805	COG2197	response regulator
LCA12A_RS05810	COG4585	Histidine kinase
LCA12A_RS05820	COG1131	(ABC) transporter
LCA12A_RS05840	COG2183	response to ionizing radiation
LCA12A_RS05845	COG3620	sequence-specific DNA binding
LCA12A_RS05855	COG1956	GAF domain-containing protein
LCA12A_RS05860	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
LCA12A_RS05865	COG1104	cysteine desulfurase activity
LCA12A_RS05875	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
LCA12A_RS05880	COG0525	valine-tRNA ligase activity
LCA12A_RS05895	COG2003	Belongs to the UPF0758 family
LCA12A_RS05900	COG1077	Cell shape determining protein MreB Mrl
LCA12A_RS05905	COG1792	Involved in formation and maintenance of cell shape
LCA12A_RS05915	COG0850	regulation of cytokinetic process
LCA12A_RS05920	COG2894	cell division
LCA12A_RS05925	COG0765	amino acid transport
LCA12A_RS05935	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LCA12A_RS05940	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LCA12A_RS05950	COG2001	Belongs to the MraZ family
LCA12A_RS05965	COG0768	penicillin binding
LCA12A_RS06015	COG3599	regulation of cell shape
LCA12A_RS06025	COG1278	Cold shock
LCA12A_RS06035	COG2814	Major facilitator Superfamily
LCA12A_RS06040	COG3853	Toxic anion resistance protein (TelA)
LCA12A_RS06050	COG0494	nUDIX hydrolase
LCA12A_RS06065	COG1104	cysteine desulfurase activity
LCA12A_RS06100	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
LCA12A_RS06110	COG1597	lipid kinase activity
LCA12A_RS06175	COG0483	inositol monophosphate 1-phosphatase activity
LCA12A_RS06180	COG1217	gtp-binding protein TYPA
LCA12A_RS06185	COG0772	Belongs to the SEDS family
LCA12A_RS06190	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
LCA12A_RS06195	COG4471	UPF0298 protein
LCA12A_RS06200	COG0742	ribosomal rna small subunit methyltransferase
LCA12A_RS06210	COG3480	Lon protease (S16) C-terminal proteolytic domain
LCA12A_RS06220	COG0658	competence protein
LCA12A_RS06220	COG2333	competence protein COMEC
LCA12A_RS06225	COG1466	dna polymerase III delta subunit
LCA12A_RS06260	COG1132	(ABC) transporter
LCA12A_RS06270	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
LCA12A_RS06290	COG0765	amino acid transport
LCA12A_RS06295	COG1126	abc transporter atp-binding protein
LCA12A_RS06305	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
LCA12A_RS06305	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LCA12A_RS06305	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LCA12A_RS06310	COG1105	Belongs to the carbohydrate kinase PfkB family
LCA12A_RS06315	COG1349	DNA-binding transcription factor activity
LCA12A_RS06325	COG2755	lipolytic protein G-D-S-L family
LCA12A_RS06325	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
LCA12A_RS06335	COG0300	oxidoreductase activity
LCA12A_RS06345	COG0542	response to heat
LCA12A_RS06360	COG0737	Belongs to the 5'-nucleotidase family
LCA12A_RS06375	COG0587	DNA-directed DNA polymerase activity
LCA12A_RS06395	COG2996	Protein conserved in bacteria
LCA12A_RS06405	COG0456	acetyltransferase
LCA12A_RS06410	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
LCA12A_RS06415	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
LCA12A_RS06420	COG1187	pseudouridine synthase activity
LCA12A_RS06425	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
LCA12A_RS06440	COG0514	ATP-dependent DNA helicase (RecQ)
LCA12A_RS06455	COG0539	negative regulation of cytoplasmic translation
LCA12A_RS06470	COG0457	Tetratricopeptide repeat
LCA12A_RS06475	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
LCA12A_RS06490	COG0488	(ABC) transporter
LCA12A_RS06505	COG1272	protein, Hemolysin III
LCA12A_RS06510	COG1307	EDD domain protein, DegV family
LCA12A_RS06515	COG2755	lipolytic protein G-D-S-L family
LCA12A_RS06525	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
LCA12A_RS06535	COG0793	Belongs to the peptidase S41A family
LCA12A_RS06535	COG3409	Peptidoglycan-binding domain 1 protein
LCA12A_RS06590	COG0758	DNA mediated transformation
LCA12A_RS06590	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
LCA12A_RS06595	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
LCA12A_RS06615	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
LCA12A_RS06630	COG0187	DNA topoisomerase II activity
LCA12A_RS06635	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
LCA12A_RS06640	COG1882	Formate acetyltransferase
LCA12A_RS06645	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
LCA12A_RS06650	COG0583	DNA-binding transcription factor activity
LCA12A_RS06655	COG1227	inorganic diphosphatase activity
LCA12A_RS06660	COG4974	Belongs to the 'phage' integrase family
LCA12A_RS06670	COG0577	efflux transmembrane transporter activity
LCA12A_RS06675	COG1136	(ABC) transporter
LCA12A_RS06680	COG5002	protein histidine kinase activity
LCA12A_RS06685	COG0745	RESPONSE REGULATOR receiver
LCA12A_RS06705	COG0778	Nitroreductase
LCA12A_RS06710	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
LCA12A_RS06745	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
LCA12A_RS06760	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
LCA12A_RS06765	COG0494	nUDIX hydrolase
LCA12A_RS06770	COG1307	EDD domain protein, DegV family
LCA12A_RS06775	COG1293	RNA-binding protein homologous to eukaryotic snRNP
LCA12A_RS06790	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
LCA12A_RS06795	COG0508	dehydrogenase complex catalyzes the overall conversion of
LCA12A_RS06800	COG0022	dehydrogenase e1 component
LCA12A_RS06805	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
LCA12A_RS06810	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LCA12A_RS06815	COG3426	butyrate kinase activity
LCA12A_RS06820	COG0280	phosphate acetyltransferase
LCA12A_RS06825	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
LCA12A_RS06830	COG0284	orotidine-5'-phosphate decarboxylase activity
LCA12A_RS06845	COG0505	Belongs to the CarA family
LCA12A_RS06850	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
LCA12A_RS06860	COG2233	PERMEase
LCA12A_RS06865	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
LCA12A_RS06870	COG0564	pseudouridine synthase activity
LCA12A_RS06875	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
LCA12A_RS06890	COG0328	RNA-DNA hybrid ribonuclease activity
LCA12A_RS06900	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LCA12A_RS06915	COG1393	Belongs to the ArsC family
LCA12A_RS06920	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LCA12A_RS06925	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LCA12A_RS06930	COG0583	DNA-binding transcription factor activity
LCA12A_RS06935	COG3590	peptidase
LCA12A_RS06940	COG0095	Lipoate-protein ligase
LCA12A_RS06960	COG0116	Belongs to the methyltransferase superfamily
LCA12A_RS06985	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
LCA12A_RS06990	COG2131	deaminase
LCA12A_RS06995	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
LCA12A_RS07010	COG0436	Aminotransferase
LCA12A_RS07020	COG1199	ATP-dependent helicase activity
LCA12A_RS07020	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
LCA12A_RS07050	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
LCA12A_RS07050	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
LCA12A_RS07065	COG2151	metal-sulfur cluster biosynthetic enzyme
LCA12A_RS07070	COG1942	4-Oxalocrotonate Tautomerase
LCA12A_RS07075	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
LCA12A_RS07080	COG2384	SAM-dependent methyltransferase
LCA12A_RS07085	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
LCA12A_RS07090	COG0358	DNA primase activity
LCA12A_RS07115	COG1381	Involved in DNA repair and RecF pathway recombination
LCA12A_RS07125	COG0295	cytidine deaminase activity
LCA12A_RS07140	COG1702	phosphate starvation-inducible protein PhoH
LCA12A_RS07145	COG1610	YqeY-like protein
LCA12A_RS07160	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
LCA12A_RS07165	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
LCA12A_RS07170	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
LCA12A_RS07195	COG1131	(ABC) transporter
LCA12A_RS07205	COG0860	N-Acetylmuramoyl-L-alanine amidase
LCA12A_RS07205	COG3103	Sh3 type 3 domain protein
LCA12A_RS07205	COG4991	sh3 domain protein
LCA12A_RS07220	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
LCA12A_RS07230	COG1385	rRNA (uridine-N3-)-methyltransferase activity
LCA12A_RS07245	COG2094	Belongs to the DNA glycosylase MPG family
LCA12A_RS07305	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
LCA12A_RS07315	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
LCA12A_RS07315	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
LCA12A_RS07360	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
LCA12A_RS07370	COG0635	Involved in the biosynthesis of porphyrin-containing compound
LCA12A_RS07375	COG0196	riboflavin kinase activity
LCA12A_RS07385	COG0861	Integral membrane protein TerC family
LCA12A_RS07410	COG2740	Nucleic-acid-binding protein implicated in transcription termination
LCA12A_RS07415	COG0195	Participates in both transcription termination and antitermination
LCA12A_RS07435	COG0750	zinc metalloprotease
LCA12A_RS07440	COG4589	Belongs to the CDS family
LCA12A_RS07445	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
LCA12A_RS07475	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
LCA12A_RS07715	COG1396	sequence-specific DNA binding
LCA12A_RS07745	COG1597	lipid kinase activity
LCA12A_RS07760	COG0204	Acyl-transferase
LCA12A_RS07765	COG0531	amino acid
LCA12A_RS07775	COG1132	(ABC) transporter
LCA12A_RS07780	COG1132	(ABC) transporter
LCA12A_RS07785	COG3763	UPF0154 protein
LCA12A_RS07790	COG4224	UPF0291 protein
LCA12A_RS07815	COG1837	Belongs to the UPF0109 family
LCA12A_RS07825	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
LCA12A_RS07840	COG0552	protein localization to endoplasmic reticulum
LCA12A_RS07845	COG1196	nuclear chromosome segregation
LCA12A_RS07850	COG0571	ribonuclease III activity
LCA12A_RS07855	COG0747	negative chemotaxis
LCA12A_RS07860	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LCA12A_RS07865	COG0601	transmembrane transport
LCA12A_RS07870	COG4608	Belongs to the ABC transporter superfamily
LCA12A_RS07880	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LCA12A_RS07890	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
LCA12A_RS07895	COG1461	Dihydroxyacetone kinase
LCA12A_RS07910	COG1564	THIamine pyrophosphokinase
LCA12A_RS07915	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
LCA12A_RS07920	COG1162	GTPase activity
LCA12A_RS07925	COG2815	serine threonine protein kinase
LCA12A_RS07925	COG0515	serine threonine protein kinase
LCA12A_RS07935	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
LCA12A_RS07935	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
LCA12A_RS07945	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
LCA12A_RS07950	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
LCA12A_RS07960	COG0194	GDP metabolic process
LCA12A_RS07975	COG0497	DNA recombination
LCA12A_RS07980	COG1438	arginine binding
LCA12A_RS07985	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
LCA12A_RS07990	COG0142	geranyltranstransferase activity
LCA12A_RS07995	COG1722	exodeoxyribonuclease VII activity
LCA12A_RS08015	COG1302	Protein conserved in bacteria
LCA12A_RS08020	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
LCA12A_RS08025	COG0006	proline dipeptidase activity
LCA12A_RS08030	COG0211	Belongs to the bacterial ribosomal protein bL27 family
LCA12A_RS08035	COG2868	ribosomal protein
LCA12A_RS08040	COG0261	This protein binds to 23S rRNA in the presence of protein L20
LCA12A_RS08075	COG0789	Transcriptional regulator
LCA12A_RS08080	COG1982	Orn Lys Arg decarboxylase major
LCA12A_RS08085	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
LCA12A_RS08100	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
LCA12A_RS08105	COG1940	carbohydrate kinase activity
LCA12A_RS08115	COG0705	Rhomboid family
LCA12A_RS08115	COG0457	Tetratricopeptide repeat
LCA12A_RS08120	COG0768	penicillin binding
LCA12A_RS08130	COG4841	protein insertion into membrane
LCA12A_RS08135	COG2197	response regulator
LCA12A_RS08140	COG4585	Histidine kinase
LCA12A_RS08150	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
LCA12A_RS08155	COG0572	uridine kinase
LCA12A_RS08160	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
LCA12A_RS08165	COG0072	phenylalanine-tRNA ligase activity
LCA12A_RS08175	COG1733	regulation of RNA biosynthetic process
LCA12A_RS08185	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LCA12A_RS08195	COG0706	membrane insertase activity
LCA12A_RS08205	COG5002	protein histidine kinase activity
LCA12A_RS08210	COG0745	RESPONSE REGULATOR receiver
LCA12A_RS08215	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
LCA12A_RS08235	COG2226	methyltransferase
LCA12A_RS08240	COG0799	negative regulation of ribosome biogenesis
LCA12A_RS08250	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
LCA12A_RS08255	COG1534	Rna-binding protein
LCA12A_RS08260	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
LCA12A_RS08265	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
LCA12A_RS08270	COG0346	lactoylglutathione lyase activity
LCA12A_RS08280	COG0400	carboxylic ester hydrolase activity
LCA12A_RS08305	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
LCA12A_RS08335	COG1484	DNA-dependent DNA replication
LCA12A_RS08340	COG3611	Membrane attachment protein
LCA12A_RS08350	COG0237	dephospho-CoA kinase activity
LCA12A_RS08355	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
LCA12A_RS08360	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
LCA12A_RS08360	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
LCA12A_RS08365	COG0670	Belongs to the BI1 family
LCA12A_RS08375	COG1674	ftsk spoiiie
LCA12A_RS08380	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LCA12A_RS08385	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LCA12A_RS08410	COG1131	(ABC) transporter
LCA12A_RS08415	COG0537	adenosine 5'-monophosphoramidase activity
LCA12A_RS08425	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
LCA12A_RS08440	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
LCA12A_RS08445	COG0564	pseudouridine synthase activity
LCA12A_RS08450	COG1438	arginine binding
LCA12A_RS08455	COG0018	arginyl-trna synthetase
LCA12A_RS08475	COG0167	dihydroorotate dehydrogenase activity
LCA12A_RS08490	COG1393	Belongs to the ArsC family
LCA12A_RS08495	COG1234	tRNA 3'-trailer cleavage
LCA12A_RS08510	COG1136	(ABC) transporter
LCA12A_RS08515	COG0745	RESPONSE REGULATOR receiver
LCA12A_RS08520	COG0642	Histidine kinase
LCA12A_RS08530	COG2217	Heavy metal translocating P-type atpase
LCA12A_RS08535	COG3682	Transcriptional regulator
LCA12A_RS08540	COG0151	Belongs to the GarS family
LCA12A_RS08550	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
LCA12A_RS08555	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
LCA12A_RS08575	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
LCA12A_RS08585	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
LCA12A_RS08590	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
LCA12A_RS08600	COG2814	Major facilitator Superfamily
LCA12A_RS08610	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
LCA12A_RS08620	COG0542	response to heat
LCA12A_RS08635	COG1253	flavin adenine dinucleotide binding
LCA12A_RS08640	COG0628	permease
LCA12A_RS08655	COG3557	Belongs to the UPF0374 family
LCA12A_RS08675	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
LCA12A_RS08685	COG2188	Transcriptional regulator
LCA12A_RS08690	COG2723	6-phospho-beta-galactosidase activity
LCA12A_RS08695	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
LCA12A_RS08705	COG1447	Phosphotransferase system cellobiose-specific component IIA
LCA12A_RS08710	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
LCA12A_RS08720	COG0028	Belongs to the TPP enzyme family
LCA12A_RS08725	COG3425	synthase
LCA12A_RS08735	COG0183	Belongs to the thiolase family
LCA12A_RS08760	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
LCA12A_RS08780	COG3091	SprT-like family
LCA12A_RS08785	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
LCA12A_RS08790	COG4120	Belongs to the binding-protein-dependent transport system permease family
LCA12A_RS08825	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
LCA12A_RS08835	COG2188	Transcriptional regulator
LCA12A_RS08840	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
LCA12A_RS08845	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
LCA12A_RS08850	COG4946	Tricorn protease homolog
LCA12A_RS08850	COG0823	Involved in the tonB-independent uptake of proteins
LCA12A_RS08850	COG1506	peptidase
LCA12A_RS08865	COG3104	oligopeptide transport
LCA12A_RS08870	COG0577	efflux transmembrane transporter activity
LCA12A_RS08870	COG1136	(ABC) transporter
LCA12A_RS08985	COG0833	amino acid
LCA12A_RS08995	COG0028	Belongs to the TPP enzyme family
LCA12A_RS09030	COG0564	pseudouridine synthase activity
LCA12A_RS09050	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
LCA12A_RS09050	COG3697	Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase
LCA12A_RS09065	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
LCA12A_RS09065	COG3697	Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase
LCA12A_RS09100	COG0511	ligase activity, forming carbon-carbon bonds
LCA12A_RS09110	COG2851	Citrate transporter
LCA12A_RS09150	COG1131	(ABC) transporter
LCA12A_RS09165	COG2814	Major facilitator Superfamily
LCA12A_RS09185	COG1725	Transcriptional regulator
LCA12A_RS09190	COG1131	(ABC) transporter
LCA12A_RS09205	COG4608	Belongs to the ABC transporter superfamily
LCA12A_RS09210	COG0444	Belongs to the ABC transporter superfamily
LCA12A_RS09220	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LCA12A_RS09225	COG0601	transmembrane transport
LCA12A_RS09230	COG4166	transmembrane transport
LCA12A_RS09240	COG0640	Transcriptional regulator
LCA12A_RS09255	COG1132	(ABC) transporter
LCA12A_RS09290	COG5549	protein import
LCA12A_RS09290	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LCA12A_RS09300	COG1349	DNA-binding transcription factor activity
LCA12A_RS09320	COG0515	serine threonine protein kinase
LCA12A_RS09320	COG2815	serine threonine protein kinase
LCA12A_RS09365	COG4690	dipeptidase activity
LCA12A_RS09370	COG1607	acyl-coa hydrolase
LCA12A_RS09375	COG3973	AAA domain
LCA12A_RS09385	COG0475	glutathione-regulated potassium exporter activity
LCA12A_RS09385	COG0569	domain protein
LCA12A_RS09390	COG2267	carboxylic ester hydrolase activity
LCA12A_RS09420	COG1136	(ABC) transporter
LCA12A_RS09425	COG0531	amino acid
LCA12A_RS09435	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
LCA12A_RS09440	COG0726	polysaccharide deacetylase
LCA12A_RS09455	COG0489	protein tyrosine kinase activity
LCA12A_RS09475	COG0463	Glycosyl transferase, family 2
LCA12A_RS09505	COG0463	Glycosyl transferase, family 2
LCA12A_RS09510	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
LCA12A_RS09525	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
LCA12A_RS09545	COG0765	amino acid transport
LCA12A_RS09550	COG0765	amino acid transport
LCA12A_RS09555	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LCA12A_RS09575	COG0735	belongs to the Fur family
LCA12A_RS09585	COG0194	GDP metabolic process
LCA12A_RS09590	COG0454	-acetyltransferase
LCA12A_RS09590	COG0456	acetyltransferase
LCA12A_RS09600	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
LCA12A_RS09630	COG0058	SHG alpha-glucan phosphorylase activity
LCA12A_RS09640	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
LCA12A_RS09650	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
LCA12A_RS09655	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
LCA12A_RS09665	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
LCA12A_RS09680	COG1393	Belongs to the ArsC family
LCA12A_RS09690	COG4464	protein tyrosine phosphatase activity
LCA12A_RS09695	COG1316	TRANSCRIPTIONal
LCA12A_RS09705	COG2801	Transposase and inactivated derivatives
LCA12A_RS09715	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
LCA12A_RS09725	COG1216	Glycosyl transferase, family 2
LCA12A_RS09725	COG1442	glycosyl transferase family 8
LCA12A_RS09730	COG0438	transferase activity, transferring glycosyl groups
LCA12A_RS09735	COG1216	Glycosyl transferase, family 2
LCA12A_RS09770	COG0562	UDP-galactopyranose mutase
LCA12A_RS09775	COG0489	protein tyrosine kinase activity
LCA12A_RS09795	COG4708	membrane
LCA12A_RS09800	COG1028	Short-chain dehydrogenase reductase Sdr
LCA12A_RS09820	COG4608	Belongs to the ABC transporter superfamily
LCA12A_RS09825	COG0444	Belongs to the ABC transporter superfamily
LCA12A_RS09830	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LCA12A_RS09835	COG0601	transmembrane transport
LCA12A_RS09840	COG4166	transmembrane transport
LCA12A_RS09845	COG2814	Major facilitator Superfamily
LCA12A_RS09850	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
LCA12A_RS09855	COG1556	Lactate utilization protein
LCA12A_RS09860	COG1139	Iron-sulfur cluster binding protein
LCA12A_RS09865	COG0247	lactate metabolic process
LCA12A_RS09875	COG1447	Phosphotransferase system cellobiose-specific component IIA
LCA12A_RS09895	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
LCA12A_RS09945	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LCA12A_RS09985	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
LCA12A_RS10000	COG1263	PTS System
LCA12A_RS10000	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LCA12A_RS10000	COG2190	(PTS) system
LCA12A_RS10005	COG0366	Alpha amylase catalytic
LCA12A_RS10010	COG1609	Transcriptional regulator
LCA12A_RS10020	COG0702	epimerase
LCA12A_RS10025	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
LCA12A_RS10040	COG0439	Biotin carboxylase
LCA12A_RS10050	COG0511	ligase activity, forming carbon-carbon bonds
LCA12A_RS10055	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
LCA12A_RS10060	COG1028	Short-chain dehydrogenase reductase Sdr
LCA12A_RS10075	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LCA12A_RS10080	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
LCA12A_RS10090	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
LCA12A_RS10095	COG2267	carboxylic ester hydrolase activity
LCA12A_RS10100	COG1979	alcohol dehydrogenase
LCA12A_RS10130	COG1846	Transcriptional regulator
LCA12A_RS10135	COG1132	(ABC) transporter
LCA12A_RS10140	COG0494	nUDIX hydrolase
LCA12A_RS10145	COG0588	phosphoglycerate mutase activity
LCA12A_RS10170	COG0628	permease
LCA12A_RS10185	COG1597	lipid kinase activity
LCA12A_RS10190	COG0028	Belongs to the TPP enzyme family
LCA12A_RS10235	COG0460	homoserine dehydrogenase
LCA12A_RS10240	COG0527	aspartate kinase activity
LCA12A_RS10245	COG2268	Band 7 protein
LCA12A_RS10260	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LCA12A_RS10265	COG0436	Aminotransferase
LCA12A_RS10285	COG0367	asparagine synthase
LCA12A_RS10300	COG0142	geranyltranstransferase activity
LCA12A_RS10310	COG4152	abc transporter atp-binding protein
LCA12A_RS10350	COG1297	OPT oligopeptide transporter protein
LCA12A_RS10370	COG0477	Major facilitator Superfamily
LCA12A_RS10380	COG2723	6-phospho-beta-galactosidase activity
LCA12A_RS10385	COG1263	PTS System
LCA12A_RS10385	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LCA12A_RS10385	COG2190	(PTS) system
LCA12A_RS10395	COG1132	(ABC) transporter
LCA12A_RS10435	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
LCA12A_RS10440	COG4988	ABC transporter
LCA12A_RS10445	COG1294	oxidase, subunit
LCA12A_RS10450	COG1271	oxidase subunit
LCA12A_RS10480	COG0697	spore germination
LCA12A_RS10485	COG2818	Glycosylase
LCA12A_RS10500	COG2365	Tyrosine phosphatase family
LCA12A_RS10505	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
LCA12A_RS10515	COG1268	BioY protein
LCA12A_RS10520	COG0789	Transcriptional regulator
LCA12A_RS10530	COG1063	alcohol dehydrogenase
LCA12A_RS10550	COG2264	protein methyltransferase activity
LCA12A_RS10560	COG0505	Belongs to the CarA family
LCA12A_RS10570	COG1253	flavin adenine dinucleotide binding
LCA12A_RS10575	COG2814	Major facilitator Superfamily
LCA12A_RS10605	COG0531	amino acid
LCA12A_RS10625	COG1266	CAAX protease self-immunity
LCA12A_RS10630	COG1316	TRANSCRIPTIONal
LCA12A_RS10640	COG1131	(ABC) transporter
LCA12A_RS10645	COG1725	Transcriptional regulator
LCA12A_RS10650	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
LCA12A_RS10655	COG0488	(ABC) transporter
LCA12A_RS10660	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
LCA12A_RS10670	COG1214	PFAM Peptidase M22, glycoprotease
LCA12A_RS10670	COG0456	acetyltransferase
LCA12A_RS10675	COG1214	PFAM Peptidase M22, glycoprotease
LCA12A_RS10715	COG0470	DNA polymerase III
LCA12A_RS10720	COG3870	Protein conserved in bacteria
LCA12A_RS10750	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
LCA12A_RS10755	COG0590	tRNA wobble adenosine to inosine editing
LCA12A_RS10765	COG2813	Specifically methylates the guanine in position
LCA12A_RS10770	COG0392	lysyltransferase activity
LCA12A_RS10770	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
LCA12A_RS10780	COG1609	Transcriptional regulator
LCA12A_RS10820	COG0477	Major facilitator Superfamily
LCA12A_RS10825	COG1012	belongs to the aldehyde dehydrogenase family
LCA12A_RS10840	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
LCA12A_RS10850	COG5646	InterPro IPR014922
LCA12A_RS10855	COG2096	Adenosyltransferase
LCA12A_RS10885	COG0250	Participates in transcription elongation, termination and antitermination
LCA12A_RS10910	COG4939	FMN-binding domain protein
LCA12A_RS10950	COG1131	(ABC) transporter
LCA12A_RS10975	COG3688	RNA-binding protein containing a PIN domain
LCA12A_RS10980	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LCA12A_RS10985	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
LCA12A_RS10995	COG0277	FAD linked oxidase domain protein
LCA12A_RS11015	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
LCA12A_RS11020	COG1737	Transcriptional regulator
LCA12A_RS11025	COG4377	Putative membrane peptidase family (DUF2324)
LCA12A_RS11040	COG4932	domain protein
LCA12A_RS11040	COG4886	Leucine-rich repeat (LRR) protein
LCA12A_RS11050	COG1131	(ABC) transporter
LCA12A_RS11060	COG4956	integral membrane protein (PIN domain superfamily)
LCA12A_RS11065	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
LCA12A_RS11070	COG0756	dUTP diphosphatase activity
LCA12A_RS11075	COG2388	GCN5-related N-acetyl-transferase
LCA12A_RS11080	COG3152	Membrane
LCA12A_RS11105	COG1131	(ABC) transporter
LCA12A_RS11115	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
LCA12A_RS11115	COG0574	Belongs to the PEP-utilizing enzyme family
LCA12A_RS11120	COG0517	IMP dehydrogenase activity
LCA12A_RS11125	COG0588	phosphoglycerate mutase activity
LCA12A_RS11140	COG1304	FMN binding
LCA12A_RS11175	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
LCA12A_RS11195	COG3764	Sortase (surface protein transpeptidase)
LCA12A_RS11235	COG1695	Transcriptional regulator
LCA12A_RS11280	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LCA12A_RS11285	COG2274	protein secretion by the type I secretion system
LCA12A_RS11355	COG0110	maltose O-acetyltransferase activity
LCA12A_RS11375	COG4989	oxidoreductase activity
LCA12A_RS11380	COG4221	oxidoreductase activity
LCA12A_RS11385	COG1902	pentaerythritol trinitrate reductase activity
LCA12A_RS11390	COG0114	fumarate hydratase activity
LCA12A_RS11405	COG1914	H( )-stimulated, divalent metal cation uptake system
LCA12A_RS11410	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
LCA12A_RS11420	COG2814	Major facilitator Superfamily
LCA12A_RS11450	COG1108	ABC-type Mn2 Zn2 transport systems permease components
LCA12A_RS11455	COG1121	(ABC) transporter
LCA12A_RS11460	COG1012	belongs to the aldehyde dehydrogenase family
LCA12A_RS11525	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
LCA12A_RS11540	COG0148	phosphopyruvate hydratase activity
LCA12A_RS11565	COG3639	organic phosphonate transmembrane transporter activity
LCA12A_RS11590	COG1116	anion transmembrane transporter activity
LCA12A_RS11595	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
LCA12A_RS11610	COG4555	ABC transporter
LCA12A_RS11650	COG0577	efflux transmembrane transporter activity
LCA12A_RS11655	COG1136	(ABC) transporter
LCA12A_RS11665	COG0789	Transcriptional regulator
LCA12A_RS11730	COG0200	Binds to the 23S rRNA
LCA12A_RS11835	COG0450	alkyl hydroperoxide reductase
LCA12A_RS11880	COG0542	response to heat
LCA12A_RS11885	COG4463	regulation of RNA biosynthetic process
LCA12A_RS11945	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
LCA12A_RS11950	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
LCA12A_RS11970	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
LCA12A_RS11975	COG0037	tRNA processing
LCA12A_RS11980	COG1098	S1 RNA binding domain
LCA12A_RS11990	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
LCA12A_RS11995	COG2244	polysaccharide biosynthetic process
LCA12A_RS12000	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
LCA12A_RS12010	COG0039	L-malate dehydrogenase activity
LCA12A_RS12025	COG1376	ErfK ybiS ycfS ynhG family protein
LCA12A_RS12030	COG0493	'glutamate synthase
LCA12A_RS12035	COG0070	glutamate synthase
LCA12A_RS12035	COG0069	glutamate synthase activity
LCA12A_RS12035	COG0067	glutamate synthase
LCA12A_RS12040	COG4708	membrane
LCA12A_RS12045	COG2337	Toxic component of a toxin-antitoxin (TA) module
LCA12A_RS12075	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
LCA12A_RS12110	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
LCA12A_RS12115	COG0504	CTP synthase activity
LCA12A_RS12135	COG0095	Lipoate-protein ligase
LCA12A_RS12140	COG1078	dGTPase activity
LCA12A_RS12160	COG1228	amidohydrolase
LCA12A_RS12165	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
LCA12A_RS12180	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
LCA12A_RS12185	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
LCA12A_RS12195	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
LCA12A_RS12200	COG4619	ABC transporter
LCA12A_RS12205	COG0390	transport system, permease component
LCA12A_RS12215	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
LCA12A_RS12220	COG4466	Protein conserved in bacteria
LCA12A_RS12225	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
LCA12A_RS12230	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
LCA12A_RS12235	COG0084	hydrolase, TatD family'
LCA12A_RS12245	COG3684	Belongs to the aldolase LacD family
LCA12A_RS12260	COG3290	protein histidine kinase activity
LCA12A_RS12265	COG1132	(ABC) transporter
LCA12A_RS12275	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LCA12A_RS12275	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LCA12A_RS12285	COG1801	Protein of unknown function DUF72
LCA12A_RS12305	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
LCA12A_RS12320	COG1881	PFAM PEBP family protein
LCA12A_RS12330	COG4086	secreted protein
LCA12A_RS12335	COG0248	Ppx GppA phosphatase
LCA12A_RS12340	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
LCA12A_RS12355	COG4989	oxidoreductase activity
LCA12A_RS12360	COG2226	methyltransferase
LCA12A_RS12370	COG0534	Mate efflux family protein
LCA12A_RS12375	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
LCA12A_RS12380	COG1704	LemA family
LCA12A_RS12390	COG1136	(ABC) transporter
LCA12A_RS12390	COG0577	efflux transmembrane transporter activity
LCA12A_RS12395	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LCA12A_RS12405	COG1174	glycine betaine transport
LCA12A_RS12410	COG3973	AAA domain
LCA12A_RS12435	COG1418	mRNA catabolic process
LCA12A_RS12445	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
LCA12A_RS12450	COG0667	Aldo Keto reductase
LCA12A_RS12455	COG0561	phosphatase activity
LCA12A_RS12475	COG0588	phosphoglycerate mutase activity
LCA12A_RS12480	COG0561	phosphatase activity
LCA12A_RS12495	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LCA12A_RS12500	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
LCA12A_RS12505	COG1811	Na channel or pump
LCA12A_RS12515	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
LCA12A_RS12515	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LCA12A_RS12515	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LCA12A_RS12520	COG1105	Belongs to the carbohydrate kinase PfkB family
LCA12A_RS12530	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
LCA12A_RS12550	COG4948	Mandelate Racemase Muconate Lactonizing
LCA12A_RS12555	COG3775	system Galactitol-specific IIC component
LCA12A_RS12560	COG3414	Phosphotransferase system galactitol-specific IIB component
LCA12A_RS12565	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
LCA12A_RS12570	COG0800	Aldolase
LCA12A_RS12580	COG1447	Phosphotransferase system cellobiose-specific component IIA
LCA12A_RS12590	COG2723	6-phospho-beta-galactosidase activity
LCA12A_RS12610	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
LCA12A_RS12615	COG2188	Transcriptional regulator
LCA12A_RS12630	COG3775	system Galactitol-specific IIC component
LCA12A_RS12645	COG1349	DNA-binding transcription factor activity
LCA12A_RS12695	COG3716	PTS system mannose fructose sorbose family IID component
LCA12A_RS12700	COG3715	PTS system
LCA12A_RS12705	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LCA12A_RS12710	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
LCA12A_RS12720	COG1414	Transcriptional regulator
LCA12A_RS12730	COG1028	Short-chain dehydrogenase reductase Sdr
LCA12A_RS12735	COG0800	Aldolase
LCA12A_RS12760	COG0463	Glycosyl transferase, family 2
LCA12A_RS12770	COG0586	Pfam SNARE associated Golgi protein
LCA12A_RS12775	COG5002	protein histidine kinase activity
LCA12A_RS12780	COG0745	RESPONSE REGULATOR receiver
LCA12A_RS12820	COG3711	transcriptional antiterminator
LCA12A_RS12830	COG2190	(PTS) system
LCA12A_RS12830	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LCA12A_RS12830	COG1263	PTS System
LCA12A_RS12865	COG3414	Phosphotransferase system galactitol-specific IIB component
LCA12A_RS12870	COG3775	system Galactitol-specific IIC component
LCA12A_RS12895	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
LCA12A_RS12910	COG2204	response regulator
LCA12A_RS12935	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
LCA12A_RS12940	COG0800	Aldolase
LCA12A_RS12960	COG3964	amidohydrolase
LCA12A_RS13005	COG3732	PTS system glucitol sorbitol-specific
LCA12A_RS13010	COG3730	PTS system glucitol sorbitol-specific
LCA12A_RS13020	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
LCA12A_RS13020	COG3711	transcriptional antiterminator
LCA12A_RS13035	COG0561	phosphatase activity
LCA12A_RS13040	COG3623	hexulose-6-phosphate isomerase
LCA12A_RS13045	COG1349	DNA-binding transcription factor activity
LCA12A_RS13050	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
LCA12A_RS13065	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
LCA12A_RS13075	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LCA12A_RS13080	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LCA12A_RS13080	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LCA12A_RS13085	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
LCA12A_RS13095	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
LCA12A_RS13100	COG3711	transcriptional antiterminator
LCA12A_RS13100	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
LCA12A_RS13110	COG1446	asparaginase
LCA12A_RS13115	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
LCA12A_RS13120	COG2188	Transcriptional regulator
LCA12A_RS13155	COG0456	acetyltransferase
LCA12A_RS13175	COG1028	Short-chain dehydrogenase reductase Sdr
LCA12A_RS13180	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LCA12A_RS13190	COG3716	PTS system mannose fructose sorbose family IID component
LCA12A_RS13195	COG1063	alcohol dehydrogenase
LCA12A_RS13220	COG0584	glycerophosphoryl diester phosphodiesterase
LCA12A_RS13225	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
LCA12A_RS13235	COG0395	ABC-type sugar transport system, permease component
LCA12A_RS13245	COG3842	ATPase activity
LCA12A_RS13250	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
LCA12A_RS13255	COG1335	isochorismatase
LCA12A_RS13280	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
LCA12A_RS13285	COG1737	Transcriptional regulator
LCA12A_RS13290	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LCA12A_RS13295	COG3716	PTS system mannose fructose sorbose family IID component
LCA12A_RS13310	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
LCA12A_RS13320	COG2076	Multidrug Resistance protein
LCA12A_RS13345	COG0604	alcohol dehydrogenase
LCA12A_RS13350	COG2365	Tyrosine phosphatase family
LCA12A_RS13375	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
LCA12A_RS13390	COG4166	transmembrane transport
LCA12A_RS13400	COG2217	Heavy metal translocating P-type atpase
LCA12A_RS13415	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LCA12A_RS13420	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
LCA12A_RS13435	COG5002	protein histidine kinase activity
LCA12A_RS13440	COG0745	RESPONSE REGULATOR receiver
LCA12A_RS13445	COG0596	Alpha beta hydrolase
LCA12A_RS13450	COG0765	amino acid transport
LCA12A_RS13480	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
LCA12A_RS13485	COG2188	Transcriptional regulator
LCA12A_RS13490	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
LCA12A_RS13495	COG1447	Phosphotransferase system cellobiose-specific component IIA
LCA12A_RS13515	COG1335	isochorismatase
LCA12A_RS13520	COG2814	Major facilitator Superfamily
LCA12A_RS13525	COG2807	transmembrane transport
LCA12A_RS13530	COG0667	Aldo Keto reductase
LCA12A_RS13540	COG3716	PTS system mannose fructose sorbose family IID component
LCA12A_RS13545	COG3715	PTS system
LCA12A_RS13580	COG0765	amino acid transport
LCA12A_RS13585	COG1126	abc transporter atp-binding protein
LCA12A_RS13625	COG4133	protoheme IX ABC transporter activity
LCA12A_RS13630	COG3001	Fructosamine kinase
LCA12A_RS13640	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LCA12A_RS13645	COG0765	amino acid transport
LCA12A_RS13660	COG0714	Associated with various cellular activities
LCA12A_RS13670	COG1305	Transglutaminase-like
LCA12A_RS13675	COG0438	transferase activity, transferring glycosyl groups
LCA12A_RS13680	COG0110	maltose O-acetyltransferase activity
LCA12A_RS13685	COG0561	phosphatase activity
LCA12A_RS13710	COG3493	citrate carrier protein
LCA12A_RS13715	COG3290	protein histidine kinase activity
LCA12A_RS13720	COG4565	transcriptional regulatory protein
LCA12A_RS13835	COG4695	Portal protein
LCA12A_RS13850	COG2261	transglycosylase associated protein
LCA12A_RS13865	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
LCA12A_RS13885	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
LCA12A_RS13895	COG2213	PTS system mannitol-specific
LCA12A_RS13905	COG0561	phosphatase activity
LCA12A_RS13925	COG1136	(ABC) transporter
LCA12A_RS13925	COG0577	efflux transmembrane transporter activity
LCA12A_RS13930	COG0577	efflux transmembrane transporter activity
LCA12A_RS13940	COG0371	Dehydrogenase
LCA12A_RS13945	COG1473	amidohydrolase
LCA12A_RS13980	COG0706	membrane insertase activity