locus-tag	class	description
LCAKO_RS00010	COG0592	DNA-directed DNA polymerase activity
LCAKO_RS00015	COG2501	S4 domain
LCAKO_RS00025	COG0187	DNA topoisomerase II activity
LCAKO_RS00035	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
LCAKO_RS00050	COG0629	single-stranded DNA binding
LCAKO_RS00060	COG1271	oxidase subunit
LCAKO_RS00065	COG1294	oxidase, subunit
LCAKO_RS00105	COG3942	CHAP domain
LCAKO_RS00125	COG0561	phosphatase activity
LCAKO_RS00145	COG3409	Peptidoglycan-binding domain 1 protein
LCAKO_RS00230	COG3409	Peptidoglycan-binding domain 1 protein
LCAKO_RS00265	COG0800	Aldolase
LCAKO_RS00295	COG2814	Major facilitator Superfamily
LCAKO_RS00305	COG1033	growth of symbiont in host cell
LCAKO_RS00305	COG2409	Drug exporters of the RND superfamily
LCAKO_RS00310	COG1309	transcriptional regulator
LCAKO_RS00325	COG1732	Glycine betaine
LCAKO_RS00360	COG2217	Heavy metal translocating P-type atpase
LCAKO_RS00365	COG2217	Heavy metal translocating P-type atpase
LCAKO_RS00375	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
LCAKO_RS00380	COG0159	tryptophan synthase activity
LCAKO_RS00390	COG0135	phosphoribosylanthranilate isomerase activity
LCAKO_RS00410	COG2814	Major facilitator Superfamily
LCAKO_RS00435	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
LCAKO_RS00455	COG0019	diaminopimelate decarboxylase activity
LCAKO_RS00460	COG0527	aspartate kinase activity
LCAKO_RS00470	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
LCAKO_RS00520	COG0438	transferase activity, transferring glycosyl groups
LCAKO_RS00585	COG0305	Participates in initiation and elongation during chromosome replication
LCAKO_RS00605	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
LCAKO_RS00610	COG1737	Transcriptional regulator
LCAKO_RS00615	COG1309	transcriptional regulator
LCAKO_RS00620	COG1136	(ABC) transporter
LCAKO_RS00620	COG0577	efflux transmembrane transporter activity
LCAKO_RS00640	COG2217	Heavy metal translocating P-type atpase
LCAKO_RS00645	COG0640	Transcriptional regulator
LCAKO_RS00650	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
LCAKO_RS00655	COG0583	DNA-binding transcription factor activity
LCAKO_RS00660	COG3620	sequence-specific DNA binding
LCAKO_RS00670	COG1131	(ABC) transporter
LCAKO_RS00680	COG1328	CTP reductase activity
LCAKO_RS00740	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
LCAKO_RS00775	COG2252	PERMEase
LCAKO_RS00785	COG0346	lactoylglutathione lyase activity
LCAKO_RS00845	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
LCAKO_RS00865	COG1131	(ABC) transporter
LCAKO_RS00875	COG1511	domain protein
LCAKO_RS00885	COG0477	Major facilitator Superfamily
LCAKO_RS00895	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
LCAKO_RS00900	COG4166	transmembrane transport
LCAKO_RS00930	COG1132	(ABC) transporter
LCAKO_RS00935	COG1396	sequence-specific DNA binding
LCAKO_RS00950	COG0446	pyridine nucleotide-disulphide oxidoreductase
LCAKO_RS00990	COG0716	FMN binding
LCAKO_RS01005	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LCAKO_RS01015	COG2261	transglycosylase associated protein
LCAKO_RS01030	COG1302	Protein conserved in bacteria
LCAKO_RS01060	COG3442	glutamine amidotransferase
LCAKO_RS01080	COG1192	Involved in chromosome partitioning
LCAKO_RS01085	COG1475	DNA binding
LCAKO_RS01090	COG4481	Protein conserved in bacteria
LCAKO_RS01095	COG0012	GTP binding
LCAKO_RS01105	COG0516	GMP reductase activity
LCAKO_RS01105	COG0517	IMP dehydrogenase activity
LCAKO_RS01125	COG1686	Belongs to the peptidase S11 family
LCAKO_RS01130	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
LCAKO_RS01140	COG1794	racemase activity, acting on amino acids and derivatives
LCAKO_RS01145	COG0656	L-ascorbic acid biosynthetic process
LCAKO_RS01150	COG1349	DNA-binding transcription factor activity
LCAKO_RS01155	COG2814	Major facilitator Superfamily
LCAKO_RS01160	COG1012	belongs to the aldehyde dehydrogenase family
LCAKO_RS01165	COG3718	enzyme involved in inositol metabolism
LCAKO_RS01170	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LCAKO_RS01175	COG3962	Belongs to the TPP enzyme family
LCAKO_RS01180	COG0673	inositol 2-dehydrogenase activity
LCAKO_RS01185	COG0673	inositol 2-dehydrogenase activity
LCAKO_RS01195	COG0191	fructose-bisphosphate aldolase activity
LCAKO_RS01200	COG1942	4-Oxalocrotonate Tautomerase
LCAKO_RS01205	COG1737	Transcriptional regulator
LCAKO_RS01210	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
LCAKO_RS01220	COG2610	gluconate transmembrane transporter activity
LCAKO_RS01230	COG1121	(ABC) transporter
LCAKO_RS01245	COG2084	Dehydrogenase
LCAKO_RS01250	COG1164	Oligoendopeptidase f
LCAKO_RS01255	COG1316	TRANSCRIPTIONal
LCAKO_RS01260	COG1114	Component of the transport system for branched-chain amino acids
LCAKO_RS01275	COG1216	Glycosyl transferase, family 2
LCAKO_RS01300	COG0488	(ABC) transporter
LCAKO_RS01325	COG3118	belongs to the thioredoxin family
LCAKO_RS01345	COG0683	leucine binding
LCAKO_RS01375	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
LCAKO_RS01385	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
LCAKO_RS01390	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
LCAKO_RS01415	COG2723	6-phospho-beta-galactosidase activity
LCAKO_RS01420	COG0446	pyridine nucleotide-disulphide oxidoreductase
LCAKO_RS01440	COG2182	Extracellular solute-binding protein
LCAKO_RS01450	COG3064	Membrane
LCAKO_RS01450	COG3525	Glycosyl hydrolase, family 20, catalytic domain
LCAKO_RS01450	COG3583	domain protein
LCAKO_RS01455	COG1482	cell wall glycoprotein biosynthetic process
LCAKO_RS01460	COG2188	Transcriptional regulator
LCAKO_RS01465	COG2222	sugar isomerase
LCAKO_RS01470	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
LCAKO_RS01480	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LCAKO_RS01485	COG3715	PTS system
LCAKO_RS01490	COG3716	PTS system mannose fructose sorbose family IID component
LCAKO_RS01495	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LCAKO_RS01495	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
LCAKO_RS01505	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
LCAKO_RS01510	COG0006	proline dipeptidase activity
LCAKO_RS01515	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
LCAKO_RS01520	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
LCAKO_RS01530	COG1363	Peptidase, m42
LCAKO_RS01540	COG2195	Cleaves the N-terminal amino acid of tripeptides
LCAKO_RS01545	COG4166	transmembrane transport
LCAKO_RS01565	COG1129	ABC transporter
LCAKO_RS01575	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
LCAKO_RS01595	COG0351	phosphomethylpyrimidine kinase
LCAKO_RS01600	COG0531	amino acid
LCAKO_RS01610	COG1609	Transcriptional regulator
LCAKO_RS01625	COG1172	Belongs to the binding-protein-dependent transport system permease family
LCAKO_RS01630	COG1879	ABC-type sugar transport system periplasmic component
LCAKO_RS01650	COG2814	Major facilitator Superfamily
LCAKO_RS01695	COG1131	(ABC) transporter
LCAKO_RS01715	COG1053	succinate dehydrogenase
LCAKO_RS01720	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
LCAKO_RS01750	COG1378	Sugar-specific transcriptional regulator TrmB
LCAKO_RS01765	COG2267	carboxylic ester hydrolase activity
LCAKO_RS01805	COG1609	Transcriptional regulator
LCAKO_RS01815	COG3716	PTS system mannose fructose sorbose family IID component
LCAKO_RS01825	COG1262	PFAM Formylglycine-generating sulfatase enzyme
LCAKO_RS01835	COG0641	radical SAM
LCAKO_RS01845	COG3069	C4-dicarboxylate transmembrane transporter activity
LCAKO_RS01860	COG2801	Transposase and inactivated derivatives
LCAKO_RS01865	COG2188	Transcriptional regulator
LCAKO_RS01890	COG3715	PTS system
LCAKO_RS01895	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LCAKO_RS01925	COG3711	transcriptional antiterminator
LCAKO_RS01940	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LCAKO_RS01940	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
LCAKO_RS01940	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LCAKO_RS01945	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LCAKO_RS01950	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LCAKO_RS01950	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LCAKO_RS01950	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
LCAKO_RS01970	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LCAKO_RS01970	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
LCAKO_RS01970	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LCAKO_RS01975	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LCAKO_RS01975	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LCAKO_RS01980	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
LCAKO_RS01995	COG0191	fructose-bisphosphate aldolase activity
LCAKO_RS02000	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LCAKO_RS02000	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LCAKO_RS02000	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
LCAKO_RS02005	COG1028	Short-chain dehydrogenase reductase Sdr
LCAKO_RS02015	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
LCAKO_RS02015	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LCAKO_RS02020	COG3715	PTS system
LCAKO_RS02025	COG3716	PTS system mannose fructose sorbose family IID component
LCAKO_RS02030	COG0246	Mannitol dehydrogenase
LCAKO_RS02035	COG1461	Dihydroxyacetone kinase
LCAKO_RS02040	COG2376	Dihydroxyacetone kinase
LCAKO_RS02045	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
LCAKO_RS02050	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
LCAKO_RS02055	COG1609	Transcriptional regulator
LCAKO_RS02065	COG2390	Transcriptional regulator
LCAKO_RS02075	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
LCAKO_RS02080	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LCAKO_RS02085	COG3715	PTS system
LCAKO_RS02090	COG3716	PTS system mannose fructose sorbose family IID component
LCAKO_RS02095	COG0191	fructose-bisphosphate aldolase activity
LCAKO_RS02100	COG0471	metal ion transport
LCAKO_RS02110	COG0583	DNA-binding transcription factor activity
LCAKO_RS02125	COG1122	ATPase activity
LCAKO_RS02135	COG4948	Mandelate Racemase Muconate Lactonizing
LCAKO_RS02140	COG2271	Major facilitator Superfamily
LCAKO_RS02155	COG0583	DNA-binding transcription factor activity
LCAKO_RS02160	COG3250	beta-galactosidase activity
LCAKO_RS02170	COG0833	amino acid
LCAKO_RS02180	COG2207	Transcriptional regulator
LCAKO_RS02220	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
LCAKO_RS02225	COG1349	DNA-binding transcription factor activity
LCAKO_RS02230	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
LCAKO_RS02235	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
LCAKO_RS02240	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
LCAKO_RS02240	COG2213	PTS system mannitol-specific
LCAKO_RS02255	COG1126	abc transporter atp-binding protein
LCAKO_RS02260	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LCAKO_RS02265	COG0765	amino acid transport
LCAKO_RS02270	COG0765	amino acid transport
LCAKO_RS02275	COG0477	Major facilitator Superfamily
LCAKO_RS02310	COG0446	pyridine nucleotide-disulphide oxidoreductase
LCAKO_RS02315	COG0561	phosphatase activity
LCAKO_RS02325	COG1609	Transcriptional regulator
LCAKO_RS02330	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LCAKO_RS02340	COG3716	PTS system mannose fructose sorbose family IID component
LCAKO_RS02355	COG0366	Alpha amylase catalytic
LCAKO_RS02360	COG1132	(ABC) transporter
LCAKO_RS02365	COG1132	(ABC) transporter
LCAKO_RS02385	COG2271	Major facilitator Superfamily
LCAKO_RS02390	COG1473	amidohydrolase
LCAKO_RS02400	COG1464	Belongs to the NlpA lipoprotein family
LCAKO_RS02430	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
LCAKO_RS02435	COG1461	Dihydroxyacetone kinase
LCAKO_RS02440	COG2376	Dihydroxyacetone kinase
LCAKO_RS02475	COG2814	Major facilitator Superfamily
LCAKO_RS02495	COG0028	Belongs to the TPP enzyme family
LCAKO_RS02510	COG2226	methyltransferase
LCAKO_RS02515	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
LCAKO_RS02520	COG0174	glutamine synthetase
LCAKO_RS02535	COG0789	Transcriptional regulator
LCAKO_RS02540	COG0656	L-ascorbic acid biosynthetic process
LCAKO_RS02550	COG1733	regulation of RNA biosynthetic process
LCAKO_RS02560	COG2723	6-phospho-beta-galactosidase activity
LCAKO_RS02570	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
LCAKO_RS02575	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
LCAKO_RS02585	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
LCAKO_RS02640	COG1131	(ABC) transporter
LCAKO_RS02670	COG0308	aminopeptidase N
LCAKO_RS02675	COG0531	amino acid
LCAKO_RS02695	COG1028	Short-chain dehydrogenase reductase Sdr
LCAKO_RS02710	COG2271	Major facilitator Superfamily
LCAKO_RS02715	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
LCAKO_RS02720	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
LCAKO_RS02725	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
LCAKO_RS02775	COG1396	sequence-specific DNA binding
LCAKO_RS03125	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
LCAKO_RS03140	COG2801	Transposase and inactivated derivatives
LCAKO_RS03145	COG1174	glycine betaine transport
LCAKO_RS03155	COG3328	transposase activity
LCAKO_RS03190	COG2801	Transposase and inactivated derivatives
LCAKO_RS03240	COG3464	Transposase
LCAKO_RS03275	COG0626	cystathionine gamma-synthase activity
LCAKO_RS03280	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LCAKO_RS03285	COG0765	amino acid transport
LCAKO_RS03295	COG1114	Component of the transport system for branched-chain amino acids
LCAKO_RS03350	COG0697	spore germination
LCAKO_RS03360	COG1131	(ABC) transporter
LCAKO_RS03380	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
LCAKO_RS03385	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
LCAKO_RS03395	COG1132	(ABC) transporter
LCAKO_RS03400	COG1132	(ABC) transporter
LCAKO_RS03405	COG2223	nitrite transmembrane transporter activity
LCAKO_RS03410	COG2188	Transcriptional regulator
LCAKO_RS03420	COG0366	Alpha amylase catalytic
LCAKO_RS03425	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LCAKO_RS03425	COG1263	PTS System
LCAKO_RS03425	COG2190	(PTS) system
LCAKO_RS03435	COG0531	amino acid
LCAKO_RS03440	COG0039	L-malate dehydrogenase activity
LCAKO_RS03445	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
LCAKO_RS03450	COG1278	Cold shock
LCAKO_RS03465	COG0488	(ABC) transporter
LCAKO_RS03470	COG0702	epimerase
LCAKO_RS03475	COG0656	L-ascorbic acid biosynthetic process
LCAKO_RS03480	COG1113	amino acid transport
LCAKO_RS03490	COG0025	NhaP-type Na H and K H
LCAKO_RS03510	COG1131	(ABC) transporter
LCAKO_RS03530	COG0604	alcohol dehydrogenase
LCAKO_RS03530	COG1028	Short-chain dehydrogenase reductase Sdr
LCAKO_RS03530	COG3321	synthase
LCAKO_RS03535	COG0004	ammonium transporteR
LCAKO_RS03545	COG1285	pathogenesis
LCAKO_RS03585	COG0488	(ABC) transporter
LCAKO_RS03590	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
LCAKO_RS03595	COG1573	uracil-dna glycosylase
LCAKO_RS03600	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
LCAKO_RS03605	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
LCAKO_RS03610	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
LCAKO_RS03615	COG1215	transferase activity, transferring glycosyl groups
LCAKO_RS03625	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
LCAKO_RS03630	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
LCAKO_RS03635	COG1609	Transcriptional regulator
LCAKO_RS03640	COG2017	converts alpha-aldose to the beta-anomer
LCAKO_RS03665	COG3775	system Galactitol-specific IIC component
LCAKO_RS03685	COG3684	Belongs to the aldolase LacD family
LCAKO_RS03700	COG1349	DNA-binding transcription factor activity
LCAKO_RS03715	COG0419	ATPase involved in DNA repair
LCAKO_RS03735	COG1194	a g-specific adenine glycosylase
LCAKO_RS03745	COG2249	NAD(P)H dehydrogenase (quinone) activity
LCAKO_RS03765	COG0351	phosphomethylpyrimidine kinase
LCAKO_RS03780	COG2910	NAD(P)H-binding
LCAKO_RS03790	COG1472	Belongs to the glycosyl hydrolase 3 family
LCAKO_RS03805	COG4120	Belongs to the binding-protein-dependent transport system permease family
LCAKO_RS03815	COG0604	alcohol dehydrogenase
LCAKO_RS03825	COG0463	Glycosyl transferase, family 2
LCAKO_RS03830	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
LCAKO_RS03840	COG0745	RESPONSE REGULATOR receiver
LCAKO_RS03845	COG5002	protein histidine kinase activity
LCAKO_RS03855	COG2508	Transcriptional regulator
LCAKO_RS03860	COG1028	Short-chain dehydrogenase reductase Sdr
LCAKO_RS03870	COG0778	Nitroreductase
LCAKO_RS03875	COG1304	FMN binding
LCAKO_RS03910	COG0604	alcohol dehydrogenase
LCAKO_RS03925	COG0628	permease
LCAKO_RS03950	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
LCAKO_RS03965	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
LCAKO_RS03970	COG3189	MarR family transcriptional regulator
LCAKO_RS03995	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
LCAKO_RS04020	COG0300	oxidoreductase activity
LCAKO_RS04025	COG0105	UTP biosynthetic process
LCAKO_RS04030	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
LCAKO_RS04035	COG2267	carboxylic ester hydrolase activity
LCAKO_RS04065	COG2267	carboxylic ester hydrolase activity
LCAKO_RS04100	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
LCAKO_RS04125	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
LCAKO_RS04130	COG0343	queuine tRNA-ribosyltransferase activity
LCAKO_RS04135	COG1862	Preprotein translocase
LCAKO_RS04140	COG1012	belongs to the aldehyde dehydrogenase family
LCAKO_RS04140	COG1454	alcohol dehydrogenase
LCAKO_RS04155	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
LCAKO_RS04160	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
LCAKO_RS04165	COG4109	DRTGG domain
LCAKO_RS04170	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
LCAKO_RS04175	COG0513	Belongs to the DEAD box helicase family
LCAKO_RS04225	COG3118	belongs to the thioredoxin family
LCAKO_RS04240	COG1696	Membrane protein involved in D-alanine export
LCAKO_RS04250	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
LCAKO_RS04255	COG1719	4-vinyl reductase, 4VR
LCAKO_RS04260	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
LCAKO_RS04270	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
LCAKO_RS04285	COG0668	transmembrane transport
LCAKO_RS04300	COG1827	regulation of RNA biosynthetic process
LCAKO_RS04305	COG0006	proline dipeptidase activity
LCAKO_RS04310	COG1609	Transcriptional regulator
LCAKO_RS04315	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
LCAKO_RS04320	COG1011	Hydrolase
LCAKO_RS04360	COG0737	Belongs to the 5'-nucleotidase family
LCAKO_RS04365	COG4470	Protein conserved in bacteria
LCAKO_RS04370	COG0647	UMP catabolic process
LCAKO_RS04385	COG0586	Pfam SNARE associated Golgi protein
LCAKO_RS04390	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
LCAKO_RS04405	COG1098	S1 RNA binding domain
LCAKO_RS04555	COG0531	amino acid
LCAKO_RS04560	COG0438	transferase activity, transferring glycosyl groups
LCAKO_RS04565	COG0438	transferase activity, transferring glycosyl groups
LCAKO_RS04580	COG0436	Aminotransferase
LCAKO_RS04595	COG1368	sulfuric ester hydrolase activity
LCAKO_RS04600	COG0735	belongs to the Fur family
LCAKO_RS04695	COG0305	Participates in initiation and elongation during chromosome replication
LCAKO_RS04825	COG0740	serine-type endopeptidase activity
LCAKO_RS04835	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
LCAKO_RS04950	COG0477	Major facilitator Superfamily
LCAKO_RS04960	COG2814	Major facilitator Superfamily
LCAKO_RS04970	COG0671	phosphoesterase, PA-phosphatase related
LCAKO_RS04985	COG2244	polysaccharide biosynthetic process
LCAKO_RS04990	COG1187	pseudouridine synthase activity
LCAKO_RS05000	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
LCAKO_RS05045	COG1396	sequence-specific DNA binding
LCAKO_RS05090	COG0305	Participates in initiation and elongation during chromosome replication
LCAKO_RS05150	COG0740	serine-type endopeptidase activity
LCAKO_RS05240	COG0438	transferase activity, transferring glycosyl groups
LCAKO_RS05245	COG0386	Belongs to the glutathione peroxidase family
LCAKO_RS05250	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
LCAKO_RS05260	COG3830	Belongs to the UPF0237 family
LCAKO_RS05285	COG2357	RelA SpoT domain protein
LCAKO_RS05295	COG0564	pseudouridine synthase activity
LCAKO_RS05305	COG3142	Participates in the control of copper homeostasis
LCAKO_RS05315	COG2706	6-phosphogluconolactonase activity
LCAKO_RS05325	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
LCAKO_RS05340	COG2226	methyltransferase
LCAKO_RS05345	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
LCAKO_RS05355	COG1674	ftsk spoiiie
LCAKO_RS05360	COG0612	Peptidase, M16
LCAKO_RS05365	COG0612	Peptidase, M16
LCAKO_RS05370	COG1028	Short-chain dehydrogenase reductase Sdr
LCAKO_RS05375	COG1426	Protein conserved in bacteria
LCAKO_RS05380	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
LCAKO_RS05390	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
LCAKO_RS05400	COG1739	Uncharacterized protein family UPF0029
LCAKO_RS05405	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
LCAKO_RS05430	COG2884	Cell division ATP-binding protein ftsE
LCAKO_RS05435	COG2177	Part of the ABC transporter FtsEX involved in
LCAKO_RS05445	COG0745	RESPONSE REGULATOR receiver
LCAKO_RS05450	COG5002	protein histidine kinase activity
LCAKO_RS05460	COG0573	inorganic phosphate transmembrane transporter activity
LCAKO_RS05465	COG0581	inorganic phosphate transmembrane transporter activity
LCAKO_RS05470	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
LCAKO_RS05475	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
LCAKO_RS05480	COG0704	Plays a role in the regulation of phosphate uptake
LCAKO_RS05495	COG1950	PFAM Membrane protein of
LCAKO_RS05505	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
LCAKO_RS05515	COG0492	ferredoxin-NADP+ reductase activity
LCAKO_RS05520	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
LCAKO_RS05525	COG0745	RESPONSE REGULATOR receiver
LCAKO_RS05530	COG2205	protein histidine kinase activity
LCAKO_RS05535	COG1136	(ABC) transporter
LCAKO_RS05555	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
LCAKO_RS05570	COG0391	Required for morphogenesis under gluconeogenic growth conditions
LCAKO_RS05580	COG1846	Transcriptional regulator
LCAKO_RS05600	COG2390	Transcriptional regulator
LCAKO_RS05640	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
LCAKO_RS05650	COG0557	exoribonuclease II activity
LCAKO_RS05665	COG1609	Transcriptional regulator
LCAKO_RS05670	COG0366	Alpha amylase catalytic
LCAKO_RS05685	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
LCAKO_RS05690	COG3842	ATPase activity
LCAKO_RS05695	COG0366	Alpha amylase catalytic
LCAKO_RS05715	COG3833	ABC-type maltose transport systems, permease component
LCAKO_RS05745	COG0395	ABC-type sugar transport system, permease component
LCAKO_RS05750	COG1175	transmembrane transport
LCAKO_RS05770	COG0561	phosphatase activity
LCAKO_RS05780	COG0280	phosphate acetyltransferase
LCAKO_RS05785	COG0802	atpase or kinase
LCAKO_RS05795	COG4152	abc transporter atp-binding protein
LCAKO_RS05800	COG1668	transmembrane transport
LCAKO_RS05810	COG0708	Exodeoxyribonuclease III
LCAKO_RS05825	COG3800	Transcriptional regulator
LCAKO_RS05825	COG1396	sequence-specific DNA binding
LCAKO_RS05835	COG1176	ABC-type spermidine putrescine transport system, permease component I
LCAKO_RS05840	COG1177	transmembrane transport
LCAKO_RS05845	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
LCAKO_RS05860	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
LCAKO_RS05865	COG1309	transcriptional regulator
LCAKO_RS05895	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
LCAKO_RS05915	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
LCAKO_RS05920	COG1459	type II secretion system
LCAKO_RS05950	COG0827	DNA restriction-modification system
LCAKO_RS05960	COG1113	amino acid transport
LCAKO_RS06010	COG0745	RESPONSE REGULATOR receiver
LCAKO_RS06015	COG3850	Histidine kinase
LCAKO_RS06015	COG5002	protein histidine kinase activity
LCAKO_RS06045	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
LCAKO_RS06105	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
LCAKO_RS06110	COG2814	Major facilitator Superfamily
LCAKO_RS06115	COG0561	phosphatase activity
LCAKO_RS06120	COG2326	polyphosphate kinase activity
LCAKO_RS06125	COG3590	peptidase
LCAKO_RS06130	COG2814	Major facilitator Superfamily
LCAKO_RS06175	COG0673	inositol 2-dehydrogenase activity
LCAKO_RS06185	COG1447	Phosphotransferase system cellobiose-specific component IIA
LCAKO_RS06205	COG0514	ATP-dependent DNA helicase (RecQ)
LCAKO_RS06210	COG2309	aminopeptidase activity
LCAKO_RS06230	COG1295	ribonuclease BN
LCAKO_RS06235	COG0716	FMN binding
LCAKO_RS06240	COG0024	Methionine aminopeptidase
LCAKO_RS06245	COG0463	Glycosyl transferase, family 2
LCAKO_RS06265	COG1210	Utp--glucose-1-phosphate uridylyltransferase
LCAKO_RS06290	COG2801	Transposase and inactivated derivatives
LCAKO_RS06305	COG2190	(PTS) system
LCAKO_RS06305	COG1263	PTS System
LCAKO_RS06305	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LCAKO_RS06310	COG3711	transcriptional antiterminator
LCAKO_RS06320	COG4485	Bacterial membrane protein, YfhO
LCAKO_RS06335	COG0463	Glycosyl transferase, family 2
LCAKO_RS06345	COG4129	membrane
LCAKO_RS06355	COG1278	Cold shock
LCAKO_RS06365	COG1705	Flagellar rod assembly protein muramidase FlgJ
LCAKO_RS06380	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
LCAKO_RS06385	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
LCAKO_RS06400	COG1368	sulfuric ester hydrolase activity
LCAKO_RS06410	COG4975	Glucose uptake
LCAKO_RS06455	COG0590	tRNA wobble adenosine to inosine editing
LCAKO_RS06480	COG3548	integral membrane protein
LCAKO_RS06530	COG2514	catechol 2,3-dioxygenase activity
LCAKO_RS06545	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
LCAKO_RS06550	COG1435	thymidine kinase activity
LCAKO_RS06560	COG2890	protein-(glutamine-N5) methyltransferase activity
LCAKO_RS06565	COG0009	L-threonylcarbamoyladenylate synthase
LCAKO_RS06580	COG0356	it plays a direct role in the translocation of protons across the membrane
LCAKO_RS06630	COG1077	Cell shape determining protein MreB Mrl
LCAKO_RS06650	COG0772	Belongs to the SEDS family
LCAKO_RS06655	COG0509	glycine decarboxylation via glycine cleavage system
LCAKO_RS06660	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
LCAKO_RS06665	COG1464	Belongs to the NlpA lipoprotein family
LCAKO_RS06670	COG1464	Belongs to the NlpA lipoprotein family
LCAKO_RS06680	COG2011	ABC-type metal ion transport system permease component
LCAKO_RS06690	COG0719	Fe-S assembly protein
LCAKO_RS06695	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
LCAKO_RS06700	COG0822	iron-sulfur transferase activity
LCAKO_RS06705	COG0719	Fe-S assembly protein
LCAKO_RS06735	COG0589	response to stress
LCAKO_RS06750	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
LCAKO_RS06755	COG0189	ligase activity
LCAKO_RS06755	COG2918	glutathione biosynthetic process
LCAKO_RS06760	COG5506	Protein of unknown function (DUF1694)
LCAKO_RS06770	COG1760	l-serine dehydratase
LCAKO_RS06775	COG1760	l-serine dehydratase
LCAKO_RS06790	COG1028	Short-chain dehydrogenase reductase Sdr
LCAKO_RS06800	COG1428	Deoxynucleoside kinase
LCAKO_RS06810	COG4166	transmembrane transport
LCAKO_RS06815	COG2205	protein histidine kinase activity
LCAKO_RS06820	COG0745	RESPONSE REGULATOR receiver
LCAKO_RS06880	COG2972	Histidine kinase
LCAKO_RS06885	COG4753	response regulator
LCAKO_RS06885	COG2207	Transcriptional regulator
LCAKO_RS06890	COG1840	ABC-type Fe3 transport system, periplasmic component
LCAKO_RS06895	COG3842	ATPase activity
LCAKO_RS06900	COG1178	ABC-type Fe3 transport system permease component
LCAKO_RS06905	COG1307	EDD domain protein, DegV family
LCAKO_RS06910	COG2197	response regulator
LCAKO_RS06915	COG4585	Histidine kinase
LCAKO_RS06920	COG0842	Transport permease protein
LCAKO_RS06925	COG1131	(ABC) transporter
LCAKO_RS06945	COG2183	response to ionizing radiation
LCAKO_RS06980	COG4372	Transposase
LCAKO_RS07005	COG3620	sequence-specific DNA binding
LCAKO_RS07080	COG0582	viral genome integration into host DNA
LCAKO_RS07090	COG1956	GAF domain-containing protein
LCAKO_RS07095	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
LCAKO_RS07110	COG1104	cysteine desulfurase activity
LCAKO_RS07125	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
LCAKO_RS07130	COG0525	valine-tRNA ligase activity
LCAKO_RS07145	COG2003	Belongs to the UPF0758 family
LCAKO_RS07150	COG1077	Cell shape determining protein MreB Mrl
LCAKO_RS07155	COG1792	Involved in formation and maintenance of cell shape
LCAKO_RS07165	COG0850	regulation of cytokinetic process
LCAKO_RS07170	COG2894	cell division
LCAKO_RS07175	COG0765	amino acid transport
LCAKO_RS07185	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LCAKO_RS07190	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LCAKO_RS07205	COG2001	Belongs to the MraZ family
LCAKO_RS07220	COG0768	penicillin binding
LCAKO_RS07250	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
LCAKO_RS07270	COG3599	regulation of cell shape
LCAKO_RS07280	COG1278	Cold shock
LCAKO_RS07290	COG2814	Major facilitator Superfamily
LCAKO_RS07295	COG3853	Toxic anion resistance protein (TelA)
LCAKO_RS07305	COG0494	nUDIX hydrolase
LCAKO_RS07320	COG1104	cysteine desulfurase activity
LCAKO_RS07355	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
LCAKO_RS07365	COG1597	lipid kinase activity
LCAKO_RS07430	COG0483	inositol monophosphate 1-phosphatase activity
LCAKO_RS07435	COG1217	gtp-binding protein TYPA
LCAKO_RS07440	COG0772	Belongs to the SEDS family
LCAKO_RS07445	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
LCAKO_RS07450	COG4471	UPF0298 protein
LCAKO_RS07455	COG0742	ribosomal rna small subunit methyltransferase
LCAKO_RS07465	COG3480	Lon protease (S16) C-terminal proteolytic domain
LCAKO_RS07475	COG2333	competence protein COMEC
LCAKO_RS07475	COG0658	competence protein
LCAKO_RS07480	COG1466	dna polymerase III delta subunit
LCAKO_RS07530	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
LCAKO_RS07540	COG0789	Transcriptional regulator
LCAKO_RS07545	COG1132	(ABC) transporter
LCAKO_RS07555	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
LCAKO_RS07580	COG0765	amino acid transport
LCAKO_RS07585	COG1126	abc transporter atp-binding protein
LCAKO_RS07595	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
LCAKO_RS07595	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LCAKO_RS07595	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LCAKO_RS07600	COG1105	Belongs to the carbohydrate kinase PfkB family
LCAKO_RS07605	COG1349	DNA-binding transcription factor activity
LCAKO_RS07615	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
LCAKO_RS07615	COG2755	lipolytic protein G-D-S-L family
LCAKO_RS07625	COG0300	oxidoreductase activity
LCAKO_RS07640	COG0542	response to heat
LCAKO_RS07655	COG0737	Belongs to the 5'-nucleotidase family
LCAKO_RS07670	COG0587	DNA-directed DNA polymerase activity
LCAKO_RS07690	COG2996	Protein conserved in bacteria
LCAKO_RS07700	COG0456	acetyltransferase
LCAKO_RS07705	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
LCAKO_RS07710	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
LCAKO_RS07715	COG1187	pseudouridine synthase activity
LCAKO_RS07720	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
LCAKO_RS07735	COG0514	ATP-dependent DNA helicase (RecQ)
LCAKO_RS07750	COG0539	negative regulation of cytoplasmic translation
LCAKO_RS07765	COG0457	Tetratricopeptide repeat
LCAKO_RS07770	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
LCAKO_RS07785	COG0488	(ABC) transporter
LCAKO_RS07800	COG1272	protein, Hemolysin III
LCAKO_RS07805	COG1307	EDD domain protein, DegV family
LCAKO_RS07810	COG2755	lipolytic protein G-D-S-L family
LCAKO_RS07820	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
LCAKO_RS07830	COG0793	Belongs to the peptidase S41A family
LCAKO_RS07830	COG3409	Peptidoglycan-binding domain 1 protein
LCAKO_RS07850	COG0758	DNA mediated transformation
LCAKO_RS07860	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
LCAKO_RS07880	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
LCAKO_RS07895	COG0187	DNA topoisomerase II activity
LCAKO_RS07900	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
LCAKO_RS07905	COG1882	Formate acetyltransferase
LCAKO_RS07910	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
LCAKO_RS07915	COG0583	DNA-binding transcription factor activity
LCAKO_RS07920	COG1227	inorganic diphosphatase activity
LCAKO_RS07925	COG4974	Belongs to the 'phage' integrase family
LCAKO_RS07935	COG0577	efflux transmembrane transporter activity
LCAKO_RS07940	COG1136	(ABC) transporter
LCAKO_RS07950	COG5002	protein histidine kinase activity
LCAKO_RS07955	COG0745	RESPONSE REGULATOR receiver
LCAKO_RS07980	COG0778	Nitroreductase
LCAKO_RS07985	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
LCAKO_RS08020	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
LCAKO_RS08035	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
LCAKO_RS08040	COG0494	nUDIX hydrolase
LCAKO_RS08045	COG1307	EDD domain protein, DegV family
LCAKO_RS08050	COG1293	RNA-binding protein homologous to eukaryotic snRNP
LCAKO_RS08065	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
LCAKO_RS08070	COG0508	dehydrogenase complex catalyzes the overall conversion of
LCAKO_RS08075	COG0022	dehydrogenase e1 component
LCAKO_RS08080	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
LCAKO_RS08085	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LCAKO_RS08090	COG3426	butyrate kinase activity
LCAKO_RS08095	COG0280	phosphate acetyltransferase
LCAKO_RS08100	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
LCAKO_RS08105	COG0284	orotidine-5'-phosphate decarboxylase activity
LCAKO_RS08120	COG0505	Belongs to the CarA family
LCAKO_RS08125	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
LCAKO_RS08135	COG2233	PERMEase
LCAKO_RS08140	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
LCAKO_RS08145	COG0564	pseudouridine synthase activity
LCAKO_RS08150	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
LCAKO_RS08165	COG0328	RNA-DNA hybrid ribonuclease activity
LCAKO_RS08175	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LCAKO_RS08190	COG1393	Belongs to the ArsC family
LCAKO_RS08195	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LCAKO_RS08200	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LCAKO_RS08210	COG0583	DNA-binding transcription factor activity
LCAKO_RS08215	COG3590	peptidase
LCAKO_RS08220	COG0095	Lipoate-protein ligase
LCAKO_RS08235	COG0116	Belongs to the methyltransferase superfamily
LCAKO_RS08260	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
LCAKO_RS08265	COG2131	deaminase
LCAKO_RS08270	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
LCAKO_RS08285	COG0436	Aminotransferase
LCAKO_RS08295	COG1199	ATP-dependent helicase activity
LCAKO_RS08295	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
LCAKO_RS08325	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
LCAKO_RS08325	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
LCAKO_RS08340	COG2151	metal-sulfur cluster biosynthetic enzyme
LCAKO_RS08345	COG1942	4-Oxalocrotonate Tautomerase
LCAKO_RS08350	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
LCAKO_RS08355	COG2384	SAM-dependent methyltransferase
LCAKO_RS08360	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
LCAKO_RS08365	COG0358	DNA primase activity
LCAKO_RS08390	COG1381	Involved in DNA repair and RecF pathway recombination
LCAKO_RS08400	COG0295	cytidine deaminase activity
LCAKO_RS08415	COG1702	phosphate starvation-inducible protein PhoH
LCAKO_RS08420	COG1610	YqeY-like protein
LCAKO_RS08435	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
LCAKO_RS08440	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
LCAKO_RS08445	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
LCAKO_RS08465	COG2130	NADP-dependent
LCAKO_RS08485	COG1131	(ABC) transporter
LCAKO_RS08495	COG0860	N-Acetylmuramoyl-L-alanine amidase
LCAKO_RS08495	COG3103	Sh3 type 3 domain protein
LCAKO_RS08495	COG4991	sh3 domain protein
LCAKO_RS08510	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
LCAKO_RS08520	COG1385	rRNA (uridine-N3-)-methyltransferase activity
LCAKO_RS08535	COG2094	Belongs to the DNA glycosylase MPG family
LCAKO_RS08570	COG2249	NAD(P)H dehydrogenase (quinone) activity
LCAKO_RS08595	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
LCAKO_RS08605	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
LCAKO_RS08605	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
LCAKO_RS08645	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
LCAKO_RS08655	COG0635	Involved in the biosynthesis of porphyrin-containing compound
LCAKO_RS08660	COG0196	riboflavin kinase activity
LCAKO_RS08670	COG0861	Integral membrane protein TerC family
LCAKO_RS08690	COG2740	Nucleic-acid-binding protein implicated in transcription termination
LCAKO_RS08695	COG0195	Participates in both transcription termination and antitermination
LCAKO_RS08715	COG0750	zinc metalloprotease
LCAKO_RS08720	COG4589	Belongs to the CDS family
LCAKO_RS08725	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
LCAKO_RS08755	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
LCAKO_RS08760	COG0204	Acyl-transferase
LCAKO_RS08765	COG0531	amino acid
LCAKO_RS08775	COG1132	(ABC) transporter
LCAKO_RS08780	COG1132	(ABC) transporter
LCAKO_RS08785	COG3763	UPF0154 protein
LCAKO_RS08790	COG4224	UPF0291 protein
LCAKO_RS08815	COG1837	Belongs to the UPF0109 family
LCAKO_RS08825	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
LCAKO_RS08840	COG0552	protein localization to endoplasmic reticulum
LCAKO_RS08845	COG1196	nuclear chromosome segregation
LCAKO_RS08850	COG0571	ribonuclease III activity
LCAKO_RS08855	COG0747	negative chemotaxis
LCAKO_RS08860	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LCAKO_RS08865	COG0601	transmembrane transport
LCAKO_RS08870	COG4608	Belongs to the ABC transporter superfamily
LCAKO_RS08880	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LCAKO_RS08890	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
LCAKO_RS08895	COG1461	Dihydroxyacetone kinase
LCAKO_RS08915	COG1564	THIamine pyrophosphokinase
LCAKO_RS08920	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
LCAKO_RS08925	COG1162	GTPase activity
LCAKO_RS08930	COG2815	serine threonine protein kinase
LCAKO_RS08930	COG0515	serine threonine protein kinase
LCAKO_RS08940	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
LCAKO_RS08940	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
LCAKO_RS08950	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
LCAKO_RS08955	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
LCAKO_RS08965	COG0194	GDP metabolic process
LCAKO_RS08985	COG0497	DNA recombination
LCAKO_RS08990	COG1438	arginine binding
LCAKO_RS08995	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
LCAKO_RS09000	COG0142	geranyltranstransferase activity
LCAKO_RS09005	COG1722	exodeoxyribonuclease VII activity
LCAKO_RS09025	COG1302	Protein conserved in bacteria
LCAKO_RS09030	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
LCAKO_RS09035	COG0006	proline dipeptidase activity
LCAKO_RS09040	COG0211	Belongs to the bacterial ribosomal protein bL27 family
LCAKO_RS09045	COG2868	ribosomal protein
LCAKO_RS09050	COG0261	This protein binds to 23S rRNA in the presence of protein L20
LCAKO_RS09085	COG0789	Transcriptional regulator
LCAKO_RS09090	COG1982	Orn Lys Arg decarboxylase major
LCAKO_RS09095	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
LCAKO_RS09110	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
LCAKO_RS09115	COG1940	carbohydrate kinase activity
LCAKO_RS09125	COG0705	Rhomboid family
LCAKO_RS09125	COG0457	Tetratricopeptide repeat
LCAKO_RS09130	COG0768	penicillin binding
LCAKO_RS09140	COG4841	protein insertion into membrane
LCAKO_RS09145	COG2197	response regulator
LCAKO_RS09150	COG4585	Histidine kinase
LCAKO_RS09160	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
LCAKO_RS09165	COG0572	uridine kinase
LCAKO_RS09170	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
LCAKO_RS09175	COG0072	phenylalanine-tRNA ligase activity
LCAKO_RS09190	COG1733	regulation of RNA biosynthetic process
LCAKO_RS09200	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LCAKO_RS09210	COG0706	membrane insertase activity
LCAKO_RS09215	COG5002	protein histidine kinase activity
LCAKO_RS09220	COG0745	RESPONSE REGULATOR receiver
LCAKO_RS09225	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
LCAKO_RS09245	COG2226	methyltransferase
LCAKO_RS09250	COG0799	negative regulation of ribosome biogenesis
LCAKO_RS09260	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
LCAKO_RS09265	COG1534	Rna-binding protein
LCAKO_RS09270	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
LCAKO_RS09275	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
LCAKO_RS09280	COG0346	lactoylglutathione lyase activity
LCAKO_RS09290	COG0400	carboxylic ester hydrolase activity
LCAKO_RS09315	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
LCAKO_RS09345	COG1484	DNA-dependent DNA replication
LCAKO_RS09350	COG3611	Membrane attachment protein
LCAKO_RS09360	COG0237	dephospho-CoA kinase activity
LCAKO_RS09365	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
LCAKO_RS09370	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
LCAKO_RS09370	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
LCAKO_RS09375	COG0670	Belongs to the BI1 family
LCAKO_RS09385	COG1674	ftsk spoiiie
LCAKO_RS09390	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LCAKO_RS09395	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LCAKO_RS09420	COG1131	(ABC) transporter
LCAKO_RS09425	COG0537	adenosine 5'-monophosphoramidase activity
LCAKO_RS09435	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
LCAKO_RS09450	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
LCAKO_RS09455	COG0564	pseudouridine synthase activity
LCAKO_RS09460	COG1438	arginine binding
LCAKO_RS09465	COG0018	arginyl-trna synthetase
LCAKO_RS09485	COG0167	dihydroorotate dehydrogenase activity
LCAKO_RS09505	COG1393	Belongs to the ArsC family
LCAKO_RS09510	COG1234	tRNA 3'-trailer cleavage
LCAKO_RS09525	COG1136	(ABC) transporter
LCAKO_RS09530	COG0745	RESPONSE REGULATOR receiver
LCAKO_RS09535	COG0642	Histidine kinase
LCAKO_RS09545	COG2217	Heavy metal translocating P-type atpase
LCAKO_RS09550	COG3682	Transcriptional regulator
LCAKO_RS09555	COG0151	Belongs to the GarS family
LCAKO_RS09565	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
LCAKO_RS09570	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
LCAKO_RS09590	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
LCAKO_RS09600	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
LCAKO_RS09605	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
LCAKO_RS09615	COG2814	Major facilitator Superfamily
LCAKO_RS09625	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
LCAKO_RS09635	COG0542	response to heat
LCAKO_RS09650	COG1253	flavin adenine dinucleotide binding
LCAKO_RS09655	COG0628	permease
LCAKO_RS09670	COG3557	Belongs to the UPF0374 family
LCAKO_RS09695	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
LCAKO_RS09705	COG2188	Transcriptional regulator
LCAKO_RS09710	COG2723	6-phospho-beta-galactosidase activity
LCAKO_RS09715	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
LCAKO_RS09725	COG1447	Phosphotransferase system cellobiose-specific component IIA
LCAKO_RS09730	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
LCAKO_RS09735	COG0028	Belongs to the TPP enzyme family
LCAKO_RS09740	COG3425	synthase
LCAKO_RS09750	COG0183	Belongs to the thiolase family
LCAKO_RS09775	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
LCAKO_RS09795	COG3091	SprT-like family
LCAKO_RS09800	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
LCAKO_RS09805	COG4120	Belongs to the binding-protein-dependent transport system permease family
LCAKO_RS09840	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
LCAKO_RS09850	COG2188	Transcriptional regulator
LCAKO_RS09855	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
LCAKO_RS09860	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
LCAKO_RS09865	COG4946	Tricorn protease homolog
LCAKO_RS09865	COG1506	peptidase
LCAKO_RS09865	COG0823	Involved in the tonB-independent uptake of proteins
LCAKO_RS09880	COG3104	oligopeptide transport
LCAKO_RS09885	COG0577	efflux transmembrane transporter activity
LCAKO_RS09885	COG1136	(ABC) transporter
LCAKO_RS10010	COG0833	amino acid
LCAKO_RS10020	COG0028	Belongs to the TPP enzyme family
LCAKO_RS10055	COG0564	pseudouridine synthase activity
LCAKO_RS10075	COG3697	Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase
LCAKO_RS10075	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
LCAKO_RS10090	COG3697	Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase
LCAKO_RS10090	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
LCAKO_RS10125	COG0511	ligase activity, forming carbon-carbon bonds
LCAKO_RS10135	COG2851	Citrate transporter
LCAKO_RS10175	COG1131	(ABC) transporter
LCAKO_RS10190	COG2814	Major facilitator Superfamily
LCAKO_RS10210	COG1725	Transcriptional regulator
LCAKO_RS10215	COG1131	(ABC) transporter
LCAKO_RS10225	COG2801	Transposase and inactivated derivatives
LCAKO_RS10245	COG1136	(ABC) transporter
LCAKO_RS10255	COG4608	Belongs to the ABC transporter superfamily
LCAKO_RS10260	COG0444	Belongs to the ABC transporter superfamily
LCAKO_RS10270	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LCAKO_RS10275	COG0601	transmembrane transport
LCAKO_RS10280	COG4166	transmembrane transport
LCAKO_RS10290	COG0640	Transcriptional regulator
LCAKO_RS10305	COG1132	(ABC) transporter
LCAKO_RS10340	COG5549	protein import
LCAKO_RS10340	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LCAKO_RS10350	COG1349	DNA-binding transcription factor activity
LCAKO_RS10435	COG1674	ftsk spoiiie
LCAKO_RS10455	COG2946	Replication initiation factor
LCAKO_RS10485	COG0433	COG0433 Predicted ATPase
LCAKO_RS10495	COG0791	NLP P60 protein
LCAKO_RS10495	COG0741	lytic transglycosylase activity
LCAKO_RS10595	COG4690	dipeptidase activity
LCAKO_RS10600	COG1607	acyl-coa hydrolase
LCAKO_RS10605	COG3973	AAA domain
LCAKO_RS10625	COG0475	glutathione-regulated potassium exporter activity
LCAKO_RS10625	COG0569	domain protein
LCAKO_RS10630	COG2267	carboxylic ester hydrolase activity
LCAKO_RS10660	COG1136	(ABC) transporter
LCAKO_RS10665	COG0531	amino acid
LCAKO_RS10675	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
LCAKO_RS10680	COG0726	polysaccharide deacetylase
LCAKO_RS10695	COG0489	protein tyrosine kinase activity
LCAKO_RS10715	COG0463	Glycosyl transferase, family 2
LCAKO_RS10745	COG0463	Glycosyl transferase, family 2
LCAKO_RS10750	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
LCAKO_RS10765	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
LCAKO_RS10785	COG0765	amino acid transport
LCAKO_RS10790	COG0765	amino acid transport
LCAKO_RS10795	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LCAKO_RS10815	COG0735	belongs to the Fur family
LCAKO_RS10825	COG0194	GDP metabolic process
LCAKO_RS10830	COG0456	acetyltransferase
LCAKO_RS10830	COG0454	-acetyltransferase
LCAKO_RS10840	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
LCAKO_RS10870	COG0058	SHG alpha-glucan phosphorylase activity
LCAKO_RS10880	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
LCAKO_RS10890	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
LCAKO_RS10895	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
LCAKO_RS10905	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
LCAKO_RS10920	COG1393	Belongs to the ArsC family
LCAKO_RS10930	COG4464	protein tyrosine phosphatase activity
LCAKO_RS10935	COG1316	TRANSCRIPTIONal
LCAKO_RS10950	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
LCAKO_RS10955	COG1091	dTDP-4-dehydrorhamnose reductase activity
LCAKO_RS10960	COG1088	dTDP-glucose 4,6-dehydratase activity
LCAKO_RS10970	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
LCAKO_RS10980	COG0297	glycogen (starch) synthase activity
LCAKO_RS11015	COG0489	protein tyrosine kinase activity
LCAKO_RS11030	COG4708	membrane
LCAKO_RS11035	COG1028	Short-chain dehydrogenase reductase Sdr
LCAKO_RS11055	COG4608	Belongs to the ABC transporter superfamily
LCAKO_RS11060	COG0444	Belongs to the ABC transporter superfamily
LCAKO_RS11065	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LCAKO_RS11070	COG0601	transmembrane transport
LCAKO_RS11075	COG4166	transmembrane transport
LCAKO_RS11080	COG2814	Major facilitator Superfamily
LCAKO_RS11085	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
LCAKO_RS11095	COG1139	Iron-sulfur cluster binding protein
LCAKO_RS11115	COG1447	Phosphotransferase system cellobiose-specific component IIA
LCAKO_RS11135	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
LCAKO_RS11175	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LCAKO_RS11205	COG2801	Transposase and inactivated derivatives
LCAKO_RS11245	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
LCAKO_RS11270	COG2190	(PTS) system
LCAKO_RS11270	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LCAKO_RS11270	COG1263	PTS System
LCAKO_RS11275	COG0366	Alpha amylase catalytic
LCAKO_RS11280	COG1609	Transcriptional regulator
LCAKO_RS11295	COG0702	epimerase
LCAKO_RS11300	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
LCAKO_RS11315	COG0439	Biotin carboxylase
LCAKO_RS11325	COG0511	ligase activity, forming carbon-carbon bonds
LCAKO_RS11330	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
LCAKO_RS11335	COG1028	Short-chain dehydrogenase reductase Sdr
LCAKO_RS11350	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LCAKO_RS11355	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
LCAKO_RS11365	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
LCAKO_RS11380	COG2267	carboxylic ester hydrolase activity
LCAKO_RS11385	COG1979	alcohol dehydrogenase
LCAKO_RS11420	COG1846	Transcriptional regulator
LCAKO_RS11425	COG1132	(ABC) transporter
LCAKO_RS11430	COG0494	nUDIX hydrolase
LCAKO_RS11435	COG0588	phosphoglycerate mutase activity
LCAKO_RS11455	COG0628	permease
LCAKO_RS11475	COG1597	lipid kinase activity
LCAKO_RS11480	COG0028	Belongs to the TPP enzyme family
LCAKO_RS11525	COG0460	homoserine dehydrogenase
LCAKO_RS11530	COG0527	aspartate kinase activity
LCAKO_RS11535	COG2268	Band 7 protein
LCAKO_RS11550	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LCAKO_RS11555	COG0436	Aminotransferase
LCAKO_RS11580	COG0367	asparagine synthase
LCAKO_RS11610	COG0142	geranyltranstransferase activity
LCAKO_RS11625	COG4152	abc transporter atp-binding protein
LCAKO_RS11665	COG1297	OPT oligopeptide transporter protein
LCAKO_RS11685	COG0477	Major facilitator Superfamily
LCAKO_RS11700	COG2723	6-phospho-beta-galactosidase activity
LCAKO_RS11705	COG2190	(PTS) system
LCAKO_RS11705	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LCAKO_RS11705	COG1263	PTS System
LCAKO_RS11715	COG1132	(ABC) transporter
LCAKO_RS11720	COG1132	(ABC) transporter
LCAKO_RS11745	COG1518	maintenance of DNA repeat elements
LCAKO_RS11775	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
LCAKO_RS11780	COG4988	ABC transporter
LCAKO_RS11785	COG1294	oxidase, subunit
LCAKO_RS11790	COG1271	oxidase subunit
LCAKO_RS11820	COG0697	spore germination
LCAKO_RS11825	COG2818	Glycosylase
LCAKO_RS11840	COG2365	Tyrosine phosphatase family
LCAKO_RS11845	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
LCAKO_RS11855	COG1268	BioY protein
LCAKO_RS11860	COG0789	Transcriptional regulator
LCAKO_RS11870	COG1063	alcohol dehydrogenase
LCAKO_RS11890	COG2264	protein methyltransferase activity
LCAKO_RS11900	COG0505	Belongs to the CarA family
LCAKO_RS11910	COG1253	flavin adenine dinucleotide binding
LCAKO_RS11915	COG2814	Major facilitator Superfamily
LCAKO_RS11950	COG0531	amino acid
LCAKO_RS11970	COG1266	CAAX protease self-immunity
LCAKO_RS11975	COG1316	TRANSCRIPTIONal
LCAKO_RS11985	COG1131	(ABC) transporter
LCAKO_RS11990	COG1725	Transcriptional regulator
LCAKO_RS11995	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
LCAKO_RS12000	COG0488	(ABC) transporter
LCAKO_RS12005	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
LCAKO_RS12015	COG1214	PFAM Peptidase M22, glycoprotease
LCAKO_RS12015	COG0456	acetyltransferase
LCAKO_RS12020	COG1214	PFAM Peptidase M22, glycoprotease
LCAKO_RS12055	COG0470	DNA polymerase III
LCAKO_RS12060	COG3870	Protein conserved in bacteria
LCAKO_RS12085	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
LCAKO_RS12095	COG0590	tRNA wobble adenosine to inosine editing
LCAKO_RS12105	COG2813	Specifically methylates the guanine in position
LCAKO_RS12110	COG0392	lysyltransferase activity
LCAKO_RS12110	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
LCAKO_RS12120	COG1609	Transcriptional regulator
LCAKO_RS12160	COG0477	Major facilitator Superfamily
LCAKO_RS12180	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
LCAKO_RS12190	COG5646	InterPro IPR014922
LCAKO_RS12195	COG2096	Adenosyltransferase
LCAKO_RS12225	COG0250	Participates in transcription elongation, termination and antitermination
LCAKO_RS12255	COG4939	FMN-binding domain protein
LCAKO_RS12300	COG3688	RNA-binding protein containing a PIN domain
LCAKO_RS12305	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LCAKO_RS12310	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
LCAKO_RS12320	COG0277	FAD linked oxidase domain protein
LCAKO_RS12350	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
LCAKO_RS12355	COG1737	Transcriptional regulator
LCAKO_RS12365	COG4377	Putative membrane peptidase family (DUF2324)
LCAKO_RS12380	COG4932	domain protein
LCAKO_RS12380	COG4886	Leucine-rich repeat (LRR) protein
LCAKO_RS12390	COG4956	integral membrane protein (PIN domain superfamily)
LCAKO_RS12395	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
LCAKO_RS12400	COG0756	dUTP diphosphatase activity
LCAKO_RS12405	COG2388	GCN5-related N-acetyl-transferase
LCAKO_RS12410	COG3152	Membrane
LCAKO_RS12435	COG1131	(ABC) transporter
LCAKO_RS12445	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
LCAKO_RS12445	COG0574	Belongs to the PEP-utilizing enzyme family
LCAKO_RS12450	COG0517	IMP dehydrogenase activity
LCAKO_RS12455	COG0588	phosphoglycerate mutase activity
LCAKO_RS12470	COG1304	FMN binding
LCAKO_RS12510	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
LCAKO_RS12530	COG3764	Sortase (surface protein transpeptidase)
LCAKO_RS12570	COG1695	Transcriptional regulator
LCAKO_RS12615	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LCAKO_RS12620	COG2274	protein secretion by the type I secretion system
LCAKO_RS12660	COG2801	Transposase and inactivated derivatives
LCAKO_RS12710	COG0110	maltose O-acetyltransferase activity
LCAKO_RS12730	COG4989	oxidoreductase activity
LCAKO_RS12735	COG4221	oxidoreductase activity
LCAKO_RS12740	COG1902	pentaerythritol trinitrate reductase activity
LCAKO_RS12745	COG0114	fumarate hydratase activity
LCAKO_RS12760	COG1914	H( )-stimulated, divalent metal cation uptake system
LCAKO_RS12765	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
LCAKO_RS12775	COG2814	Major facilitator Superfamily
LCAKO_RS12805	COG1108	ABC-type Mn2 Zn2 transport systems permease components
LCAKO_RS12810	COG1121	(ABC) transporter
LCAKO_RS12815	COG1012	belongs to the aldehyde dehydrogenase family
LCAKO_RS12905	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
LCAKO_RS12915	COG3464	Transposase
LCAKO_RS12920	COG0148	phosphopyruvate hydratase activity
LCAKO_RS12940	COG3639	organic phosphonate transmembrane transporter activity
LCAKO_RS12965	COG1116	anion transmembrane transporter activity
LCAKO_RS12970	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
LCAKO_RS12985	COG4555	ABC transporter
LCAKO_RS13040	COG1674	ftsk spoiiie
LCAKO_RS13065	COG2946	Replication initiation factor
LCAKO_RS13090	COG0433	COG0433 Predicted ATPase
LCAKO_RS13100	COG0741	lytic transglycosylase activity
LCAKO_RS13100	COG0791	NLP P60 protein
LCAKO_RS13130	COG2801	Transposase and inactivated derivatives
LCAKO_RS13145	COG0489	protein tyrosine kinase activity
LCAKO_RS13165	COG2244	polysaccharide biosynthetic process
LCAKO_RS13170	COG1216	Glycosyl transferase, family 2
LCAKO_RS13170	COG0463	Glycosyl transferase, family 2
LCAKO_RS13180	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
LCAKO_RS13180	COG1215	transferase activity, transferring glycosyl groups
LCAKO_RS13260	COG0577	efflux transmembrane transporter activity
LCAKO_RS13265	COG1136	(ABC) transporter
LCAKO_RS13275	COG0789	Transcriptional regulator
LCAKO_RS13345	COG0200	Binds to the 23S rRNA
LCAKO_RS13455	COG0450	alkyl hydroperoxide reductase
LCAKO_RS13505	COG0542	response to heat
LCAKO_RS13510	COG4463	regulation of RNA biosynthetic process
LCAKO_RS13580	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
LCAKO_RS13585	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
LCAKO_RS13625	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
LCAKO_RS13630	COG0037	tRNA processing
LCAKO_RS13635	COG1098	S1 RNA binding domain
LCAKO_RS13645	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
LCAKO_RS13650	COG2244	polysaccharide biosynthetic process
LCAKO_RS13655	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
LCAKO_RS13665	COG0039	L-malate dehydrogenase activity
LCAKO_RS13690	COG1376	ErfK ybiS ycfS ynhG family protein
LCAKO_RS13695	COG0493	'glutamate synthase
LCAKO_RS13700	COG0069	glutamate synthase activity
LCAKO_RS13700	COG0070	glutamate synthase
LCAKO_RS13700	COG0067	glutamate synthase
LCAKO_RS13705	COG4708	membrane
LCAKO_RS13710	COG2337	Toxic component of a toxin-antitoxin (TA) module
LCAKO_RS13735	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
LCAKO_RS13760	COG3464	Transposase
LCAKO_RS13780	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
LCAKO_RS13785	COG0504	CTP synthase activity
LCAKO_RS13805	COG0095	Lipoate-protein ligase
LCAKO_RS13810	COG1078	dGTPase activity
LCAKO_RS13840	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
LCAKO_RS13845	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
LCAKO_RS13855	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
LCAKO_RS13860	COG4619	ABC transporter
LCAKO_RS13865	COG0390	transport system, permease component
LCAKO_RS13875	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
LCAKO_RS13880	COG4466	Protein conserved in bacteria
LCAKO_RS13885	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
LCAKO_RS13890	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
LCAKO_RS13895	COG0084	hydrolase, TatD family'
LCAKO_RS13905	COG3684	Belongs to the aldolase LacD family
LCAKO_RS13920	COG3290	protein histidine kinase activity
LCAKO_RS13935	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LCAKO_RS13935	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LCAKO_RS13945	COG1801	Protein of unknown function DUF72
LCAKO_RS13965	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
LCAKO_RS13980	COG1881	PFAM PEBP family protein
LCAKO_RS13990	COG4086	secreted protein
LCAKO_RS13995	COG0248	Ppx GppA phosphatase
LCAKO_RS14000	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
LCAKO_RS14010	COG4989	oxidoreductase activity
LCAKO_RS14015	COG2226	methyltransferase
LCAKO_RS14025	COG0534	Mate efflux family protein
LCAKO_RS14030	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
LCAKO_RS14035	COG1704	LemA family
LCAKO_RS14050	COG1136	(ABC) transporter
LCAKO_RS14050	COG0577	efflux transmembrane transporter activity
LCAKO_RS14055	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LCAKO_RS14065	COG1174	glycine betaine transport
LCAKO_RS14070	COG3973	AAA domain
LCAKO_RS14075	COG0583	DNA-binding transcription factor activity
LCAKO_RS14100	COG1418	mRNA catabolic process
LCAKO_RS14110	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
LCAKO_RS14115	COG0667	Aldo Keto reductase
LCAKO_RS14120	COG0561	phosphatase activity
LCAKO_RS14145	COG0588	phosphoglycerate mutase activity
LCAKO_RS14150	COG0561	phosphatase activity
LCAKO_RS14165	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LCAKO_RS14170	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
LCAKO_RS14175	COG1811	Na channel or pump
LCAKO_RS14195	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LCAKO_RS14195	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LCAKO_RS14195	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
LCAKO_RS14200	COG1105	Belongs to the carbohydrate kinase PfkB family
LCAKO_RS14210	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
LCAKO_RS14215	COG3464	Transposase
LCAKO_RS14235	COG4948	Mandelate Racemase Muconate Lactonizing
LCAKO_RS14240	COG3775	system Galactitol-specific IIC component
LCAKO_RS14245	COG3414	Phosphotransferase system galactitol-specific IIB component
LCAKO_RS14250	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
LCAKO_RS14255	COG0800	Aldolase
LCAKO_RS14265	COG1447	Phosphotransferase system cellobiose-specific component IIA
LCAKO_RS14275	COG2723	6-phospho-beta-galactosidase activity
LCAKO_RS14280	COG1940	carbohydrate kinase activity
LCAKO_RS14300	COG2188	Transcriptional regulator
LCAKO_RS14320	COG3775	system Galactitol-specific IIC component
LCAKO_RS14335	COG1349	DNA-binding transcription factor activity
LCAKO_RS14375	COG0463	Glycosyl transferase, family 2
LCAKO_RS14385	COG0586	Pfam SNARE associated Golgi protein
LCAKO_RS14390	COG5002	protein histidine kinase activity
LCAKO_RS14395	COG0745	RESPONSE REGULATOR receiver
LCAKO_RS14430	COG1263	PTS System
LCAKO_RS14430	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LCAKO_RS14465	COG3711	transcriptional antiterminator
LCAKO_RS14475	COG1263	PTS System
LCAKO_RS14475	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LCAKO_RS14475	COG2190	(PTS) system
LCAKO_RS14500	COG3414	Phosphotransferase system galactitol-specific IIB component
LCAKO_RS14505	COG3775	system Galactitol-specific IIC component
LCAKO_RS14530	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
LCAKO_RS14545	COG2204	response regulator
LCAKO_RS14570	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
LCAKO_RS14575	COG0800	Aldolase
LCAKO_RS14595	COG3964	amidohydrolase
LCAKO_RS14650	COG3732	PTS system glucitol sorbitol-specific
LCAKO_RS14655	COG3730	PTS system glucitol sorbitol-specific
LCAKO_RS14665	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
LCAKO_RS14665	COG3711	transcriptional antiterminator
LCAKO_RS14680	COG0561	phosphatase activity
LCAKO_RS14685	COG3623	hexulose-6-phosphate isomerase
LCAKO_RS14690	COG1349	DNA-binding transcription factor activity
LCAKO_RS14695	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
LCAKO_RS14710	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
LCAKO_RS14725	COG1063	alcohol dehydrogenase
LCAKO_RS14740	COG3716	PTS system mannose fructose sorbose family IID component
LCAKO_RS14745	COG3715	PTS system
LCAKO_RS14750	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LCAKO_RS14760	COG1063	alcohol dehydrogenase
LCAKO_RS14765	COG1349	DNA-binding transcription factor activity
LCAKO_RS14770	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
LCAKO_RS14780	COG1446	asparaginase
LCAKO_RS14785	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
LCAKO_RS14790	COG2188	Transcriptional regulator
LCAKO_RS14820	COG1063	alcohol dehydrogenase
LCAKO_RS14825	COG3716	PTS system mannose fructose sorbose family IID component
LCAKO_RS14835	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LCAKO_RS14835	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
LCAKO_RS14845	COG3711	transcriptional antiterminator
LCAKO_RS14845	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
LCAKO_RS14855	COG0456	acetyltransferase
LCAKO_RS14865	COG0477	Major facilitator Superfamily
LCAKO_RS14870	COG0456	acetyltransferase
LCAKO_RS14900	COG0584	glycerophosphoryl diester phosphodiesterase
LCAKO_RS14905	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
LCAKO_RS14915	COG0395	ABC-type sugar transport system, permease component
LCAKO_RS14925	COG3842	ATPase activity
LCAKO_RS14930	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
LCAKO_RS14935	COG1335	isochorismatase
LCAKO_RS14950	COG4948	Mandelate Racemase Muconate Lactonizing
LCAKO_RS14960	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
LCAKO_RS14965	COG1737	Transcriptional regulator
LCAKO_RS14970	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LCAKO_RS14970	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
LCAKO_RS14975	COG3716	PTS system mannose fructose sorbose family IID component
LCAKO_RS14990	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
LCAKO_RS15000	COG2076	Multidrug Resistance protein
LCAKO_RS15030	COG2365	Tyrosine phosphatase family
LCAKO_RS15125	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
LCAKO_RS15140	COG4166	transmembrane transport
LCAKO_RS15150	COG2217	Heavy metal translocating P-type atpase
LCAKO_RS15155	COG3464	Transposase
LCAKO_RS15170	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LCAKO_RS15185	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
LCAKO_RS15200	COG5002	protein histidine kinase activity
LCAKO_RS15205	COG0745	RESPONSE REGULATOR receiver
LCAKO_RS15210	COG0596	Alpha beta hydrolase
LCAKO_RS15215	COG0765	amino acid transport
LCAKO_RS15240	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
LCAKO_RS15245	COG2188	Transcriptional regulator
LCAKO_RS15250	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
LCAKO_RS15255	COG1447	Phosphotransferase system cellobiose-specific component IIA
LCAKO_RS15275	COG1335	isochorismatase
LCAKO_RS15280	COG2814	Major facilitator Superfamily
LCAKO_RS15285	COG2807	transmembrane transport
LCAKO_RS15290	COG0667	Aldo Keto reductase
LCAKO_RS15300	COG3716	PTS system mannose fructose sorbose family IID component
LCAKO_RS15305	COG3715	PTS system
LCAKO_RS15335	COG0765	amino acid transport
LCAKO_RS15340	COG1126	abc transporter atp-binding protein
LCAKO_RS15380	COG4133	protoheme IX ABC transporter activity
LCAKO_RS15385	COG3001	Fructosamine kinase
LCAKO_RS15395	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LCAKO_RS15400	COG0765	amino acid transport
LCAKO_RS15415	COG0714	Associated with various cellular activities
LCAKO_RS15430	COG0438	transferase activity, transferring glycosyl groups
LCAKO_RS15435	COG0110	maltose O-acetyltransferase activity
LCAKO_RS15440	COG0561	phosphatase activity
LCAKO_RS15465	COG3493	citrate carrier protein
LCAKO_RS15470	COG3290	protein histidine kinase activity
LCAKO_RS15475	COG4565	transcriptional regulatory protein
LCAKO_RS15590	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
LCAKO_RS15610	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
LCAKO_RS15620	COG2213	PTS system mannitol-specific
LCAKO_RS15630	COG0561	phosphatase activity
LCAKO_RS15650	COG1136	(ABC) transporter
LCAKO_RS15650	COG0577	efflux transmembrane transporter activity
LCAKO_RS15655	COG0577	efflux transmembrane transporter activity
LCAKO_RS15665	COG2723	6-phospho-beta-galactosidase activity
LCAKO_RS15670	COG1263	PTS System
LCAKO_RS15670	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LCAKO_RS15670	COG2190	(PTS) system
LCAKO_RS15675	COG3711	transcriptional antiterminator
LCAKO_RS15680	COG0371	Dehydrogenase
LCAKO_RS15685	COG1473	amidohydrolase
LCAKO_RS15725	COG0706	membrane insertase activity
LCAKO_RS15880	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LCAKO_RS15900	COG3711	transcriptional antiterminator
LCAKO_RS15905	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
LCAKO_RS15905	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
LCAKO_RS15915	COG1447	Phosphotransferase system cellobiose-specific component IIA
LCAKO_RS15935	COG1045	serine acetyltransferase
LCAKO_RS15940	COG0626	cystathionine gamma-synthase activity
LCAKO_RS15945	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
LCAKO_RS16040	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
LCAKO_RS16055	COG1472	Belongs to the glycosyl hydrolase 3 family
LCAKO_RS16070	COG1192	Involved in chromosome partitioning