locus-tag	class	description
CFN49_RS00030	COG1418	mRNA catabolic process
CFN49_RS00035	COG0477	Major facilitator Superfamily
CFN49_RS00050	COG3328	transposase activity
CFN49_RS00055	COG0745	RESPONSE REGULATOR receiver
CFN49_RS00060	COG3158	transport of potassium into the cell
CFN49_RS00095	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CFN49_RS00105	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CFN49_RS00120	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CFN49_RS00160	COG2826	transposase and inactivated derivatives, IS30 family
CFN49_RS00240	COG2801	Transposase and inactivated derivatives
CFN49_RS00255	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CFN49_RS00290	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
CFN49_RS00310	COG0783	Belongs to the Dps family
CFN49_RS00315	COG0640	Transcriptional regulator
CFN49_RS00325	COG3118	belongs to the thioredoxin family
CFN49_RS00330	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CFN49_RS00340	COG0492	ferredoxin-NADP+ reductase activity
CFN49_RS00350	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CFN49_RS00375	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
CFN49_RS00380	COG0592	DNA-directed DNA polymerase activity
CFN49_RS00385	COG2501	S4 domain
CFN49_RS00390	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
CFN49_RS00395	COG0187	DNA topoisomerase II activity
CFN49_RS00405	COG0360	Binds together with S18 to 16S ribosomal RNA
CFN49_RS00410	COG0629	single-stranded DNA binding
CFN49_RS00415	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
CFN49_RS00425	COG0359	binds to the 23S rRNA
CFN49_RS00430	COG0305	Participates in initiation and elongation during chromosome replication
CFN49_RS00435	COG2814	Major facilitator Superfamily
CFN49_RS00440	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
CFN49_RS00445	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
CFN49_RS00450	COG4166	transmembrane transport
CFN49_RS00455	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
CFN49_RS00460	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
CFN49_RS00465	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
CFN49_RS00470	COG0297	glycogen (starch) synthase activity
CFN49_RS00475	COG0058	SHG alpha-glucan phosphorylase activity
CFN49_RS00480	COG0366	Alpha amylase catalytic
CFN49_RS00480	COG3103	Sh3 type 3 domain protein
CFN49_RS00490	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CFN49_RS00495	COG1554	hydrolase, family 65, central catalytic
CFN49_RS00505	COG1278	Cold shock
CFN49_RS00520	COG0745	RESPONSE REGULATOR receiver
CFN49_RS00525	COG5002	protein histidine kinase activity
CFN49_RS00535	COG4853	Protein conserved in bacteria
CFN49_RS00540	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
CFN49_RS00545	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CFN49_RS00550	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
CFN49_RS00560	COG1012	belongs to the aldehyde dehydrogenase family
CFN49_RS00565	COG3586	endonuclease activity
CFN49_RS00570	COG1573	uracil-dna glycosylase
CFN49_RS00590	COG3976	FMN-binding domain protein
CFN49_RS00590	COG1053	succinate dehydrogenase
CFN49_RS00590	COG0431	NADPH-dependent FMN reductase
CFN49_RS00595	COG0471	metal ion transport
CFN49_RS00610	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CFN49_RS00615	COG1028	Short-chain dehydrogenase reductase Sdr
CFN49_RS00625	COG0778	Nitroreductase
CFN49_RS00630	COG2508	Transcriptional regulator
CFN49_RS00640	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CFN49_RS00645	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
CFN49_RS00655	COG2365	Tyrosine phosphatase family
CFN49_RS00660	COG2368	4-hydroxyphenylacetate
CFN49_RS00680	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
CFN49_RS00715	COG0604	alcohol dehydrogenase
CFN49_RS00740	COG2267	carboxylic ester hydrolase activity
CFN49_RS00745	COG3022	response to hydroperoxide
CFN49_RS00755	COG4166	transmembrane transport
CFN49_RS00780	COG1122	ATPase activity
CFN49_RS00785	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
CFN49_RS00790	COG0310	cobalt ion transport
CFN49_RS00795	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CFN49_RS00800	COG3875	lactate racemase activity
CFN49_RS00805	COG1691	(AIR) carboxylase
CFN49_RS00810	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
CFN49_RS00815	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
CFN49_RS00820	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
CFN49_RS00825	COG1606	tRNA processing
CFN49_RS00835	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
CFN49_RS00840	COG0351	phosphomethylpyrimidine kinase
CFN49_RS00845	COG0352	thiamine-phosphate diphosphorylase activity
CFN49_RS00855	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
CFN49_RS00870	COG1113	amino acid transport
CFN49_RS00880	COG2267	carboxylic ester hydrolase activity
CFN49_RS00890	COG1983	PspC domain protein
CFN49_RS00935	COG0656	L-ascorbic acid biosynthetic process
CFN49_RS00940	COG0667	Aldo Keto reductase
CFN49_RS00965	COG1902	pentaerythritol trinitrate reductase activity
CFN49_RS00970	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
CFN49_RS00975	COG1122	ATPase activity
CFN49_RS00980	COG4720	Psort location CytoplasmicMembrane, score
CFN49_RS00990	COG2188	Transcriptional regulator
CFN49_RS01015	COG1028	Short-chain dehydrogenase reductase Sdr
CFN49_RS01020	COG1131	(ABC) transporter
CFN49_RS01035	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
CFN49_RS01040	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
CFN49_RS01045	COG1309	transcriptional regulator
CFN49_RS01050	COG2376	Dihydroxyacetone kinase
CFN49_RS01055	COG2376	Dihydroxyacetone kinase
CFN49_RS01060	COG1461	Dihydroxyacetone kinase
CFN49_RS01065	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
CFN49_RS01070	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
CFN49_RS01075	COG1609	Transcriptional regulator
CFN49_RS01080	COG1609	Transcriptional regulator
CFN49_RS01085	COG0366	Alpha amylase catalytic
CFN49_RS01090	COG2182	Extracellular solute-binding protein
CFN49_RS01095	COG1175	transmembrane transport
CFN49_RS01100	COG3833	ABC-type maltose transport systems, permease component
CFN49_RS01110	COG0366	Alpha amylase catalytic
CFN49_RS01115	COG3842	ATPase activity
CFN49_RS01165	COG1757	Na H antiporter
CFN49_RS01190	COG4166	transmembrane transport
CFN49_RS01195	COG4166	transmembrane transport
CFN49_RS01205	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CFN49_RS01210	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
CFN49_RS01215	COG0406	alpha-ribazole phosphatase activity
CFN49_RS01220	COG0667	Aldo Keto reductase
CFN49_RS01250	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CFN49_RS01255	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CFN49_RS01260	COG0488	(ABC) transporter
CFN49_RS01270	COG1122	ATPase activity
CFN49_RS01280	COG0386	Belongs to the glutathione peroxidase family
CFN49_RS01290	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CFN49_RS01305	COG0363	glucosamine-6-phosphate deaminase activity
CFN49_RS01315	COG3976	FMN-binding domain protein
CFN49_RS01315	COG1053	succinate dehydrogenase
CFN49_RS01330	COG2213	PTS system mannitol-specific
CFN49_RS01340	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
CFN49_RS01345	COG0246	Mannitol dehydrogenase
CFN49_RS01355	COG3118	belongs to the thioredoxin family
CFN49_RS01385	COG0431	NADPH-dependent FMN reductase
CFN49_RS01390	COG2188	Transcriptional regulator
CFN49_RS01395	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CFN49_RS01410	COG3964	amidohydrolase
CFN49_RS01430	COG1045	serine acetyltransferase
CFN49_RS01435	COG0626	cystathionine gamma-synthase activity
CFN49_RS01440	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CFN49_RS01470	COG2188	Transcriptional regulator
CFN49_RS01475	COG0366	Alpha amylase catalytic
CFN49_RS01480	COG2190	(PTS) system
CFN49_RS01480	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CFN49_RS01480	COG1263	PTS System
CFN49_RS01485	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CFN49_RS01485	COG2190	(PTS) system
CFN49_RS01485	COG1263	PTS System
CFN49_RS01495	COG0163	prenyltransferase activity
CFN49_RS01505	COG1959	2 iron, 2 sulfur cluster binding
CFN49_RS01510	COG1309	transcriptional regulator
CFN49_RS01515	COG1914	H( )-stimulated, divalent metal cation uptake system
CFN49_RS01535	COG2814	Major facilitator Superfamily
CFN49_RS01545	COG5002	protein histidine kinase activity
CFN49_RS01550	COG0745	RESPONSE REGULATOR receiver
CFN49_RS01560	COG1737	Transcriptional regulator
CFN49_RS01565	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CFN49_RS01580	COG1316	TRANSCRIPTIONal
CFN49_RS01585	COG0277	FAD linked oxidase domain protein
CFN49_RS01595	COG2357	RelA SpoT domain protein
CFN49_RS01605	COG2409	Drug exporters of the RND superfamily
CFN49_RS01605	COG1033	growth of symbiont in host cell
CFN49_RS01605	COG2409	Drug exporters of the RND superfamily
CFN49_RS01605	COG1033	growth of symbiont in host cell
CFN49_RS01610	COG2818	Glycosylase
CFN49_RS01620	COG0577	efflux transmembrane transporter activity
CFN49_RS01625	COG1136	(ABC) transporter
CFN49_RS01640	COG0741	lytic transglycosylase activity
CFN49_RS01645	COG3942	CHAP domain
CFN49_RS01645	COG1388	LysM domain
CFN49_RS01675	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CFN49_RS01685	COG1846	Transcriptional regulator
CFN49_RS01690	COG1252	NADH dehydrogenase
CFN49_RS01730	COG3842	ATPase activity
CFN49_RS01760	COG1725	Transcriptional regulator
CFN49_RS01765	COG1131	(ABC) transporter
CFN49_RS01775	COG1012	belongs to the aldehyde dehydrogenase family
CFN49_RS01775	COG1454	alcohol dehydrogenase
CFN49_RS01810	COG1268	BioY protein
CFN49_RS01835	COG2011	ABC-type metal ion transport system permease component
CFN49_RS01840	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CFN49_RS01845	COG0436	Aminotransferase
CFN49_RS01855	COG1682	transport, permease protein
CFN49_RS01860	COG1134	teichoic acid transport
CFN49_RS01875	COG2814	Major facilitator Superfamily
CFN49_RS01880	COG0004	ammonium transporteR
CFN49_RS01900	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
CFN49_RS01910	COG3759	membrane
CFN49_RS01915	COG1881	PFAM PEBP family protein
CFN49_RS01945	COG0300	oxidoreductase activity
CFN49_RS01965	COG1125	glycine betaine transport
CFN49_RS01975	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CFN49_RS01985	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
CFN49_RS02015	COG0110	maltose O-acetyltransferase activity
CFN49_RS02025	COG0561	phosphatase activity
CFN49_RS02035	COG0561	phosphatase activity
CFN49_RS02040	COG1114	Component of the transport system for branched-chain amino acids
CFN49_RS02085	COG0463	Glycosyl transferase, family 2
CFN49_RS02110	COG3279	Response regulator of the LytR AlgR family
CFN49_RS02135	COG2274	protein secretion by the type I secretion system
CFN49_RS02175	COG3973	AAA domain
CFN49_RS02180	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CFN49_RS02185	COG0180	Tryptophanyl-tRNA synthetase
CFN49_RS02190	COG2188	Transcriptional regulator
CFN49_RS02195	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CFN49_RS02210	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CFN49_RS02215	COG2723	6-phospho-beta-galactosidase activity
CFN49_RS02220	COG1940	carbohydrate kinase activity
CFN49_RS02230	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CFN49_RS02245	COG0248	Ppx GppA phosphatase
CFN49_RS02260	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
CFN49_RS02265	COG1801	Protein of unknown function DUF72
CFN49_RS02275	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CFN49_RS02275	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CFN49_RS02280	COG2814	Major facilitator Superfamily
CFN49_RS02285	COG0084	hydrolase, TatD family'
CFN49_RS02290	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
CFN49_RS02295	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
CFN49_RS02300	COG4466	Protein conserved in bacteria
CFN49_RS02305	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
CFN49_RS02310	COG1073	alpha beta
CFN49_RS02315	COG1121	(ABC) transporter
CFN49_RS02320	COG1321	iron dependent repressor
CFN49_RS02320	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CFN49_RS02345	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CFN49_RS02350	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
CFN49_RS02360	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CFN49_RS02380	COG1078	dGTPase activity
CFN49_RS02385	COG0095	Lipoate-protein ligase
CFN49_RS02395	COG3343	RNA polymerase activity
CFN49_RS02400	COG0504	CTP synthase activity
CFN49_RS02405	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
CFN49_RS02410	COG0814	amino acid
CFN49_RS02420	COG1760	l-serine dehydratase
CFN49_RS02425	COG1760	l-serine dehydratase
CFN49_RS02440	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CFN49_RS02445	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
CFN49_RS02450	COG0254	rRNA binding
CFN49_RS02460	COG3764	Sortase (surface protein transpeptidase)
CFN49_RS02465	COG1704	LemA family
CFN49_RS02470	COG0501	Belongs to the peptidase M48B family
CFN49_RS02480	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
CFN49_RS02500	COG0736	holo-[acyl-carrier-protein] synthase activity
CFN49_RS02505	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CFN49_RS02510	COG2337	Toxic component of a toxin-antitoxin (TA) module
CFN49_RS02515	COG3158	transport of potassium into the cell
CFN49_RS02520	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
CFN49_RS02525	COG0505	Belongs to the CarA family
CFN49_RS02530	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
CFN49_RS02535	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
CFN49_RS02540	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
CFN49_RS02545	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CFN49_RS02550	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
CFN49_RS02570	COG0039	L-malate dehydrogenase activity
CFN49_RS02575	COG0193	aminoacyl-tRNA hydrolase activity
CFN49_RS02580	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CFN49_RS02585	COG2244	polysaccharide biosynthetic process
CFN49_RS02590	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
CFN49_RS02600	COG1098	S1 RNA binding domain
CFN49_RS02605	COG0037	tRNA processing
CFN49_RS02620	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
CFN49_RS02625	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CFN49_RS02630	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
CFN49_RS02670	COG3104	oligopeptide transport
CFN49_RS02720	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CFN49_RS02730	COG2188	Transcriptional regulator
CFN49_RS02740	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
CFN49_RS02745	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
CFN49_RS02760	COG2183	response to ionizing radiation
CFN49_RS02765	COG3091	SprT-like family
CFN49_RS02770	COG0460	homoserine dehydrogenase
CFN49_RS02775	COG0083	homoserine kinase activity
CFN49_RS02795	COG3715	PTS system
CFN49_RS02800	COG3716	PTS system mannose fructose sorbose family IID component
CFN49_RS02810	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
CFN49_RS02810	COG3933	PFAM sigma-54 factor interaction domain-containing protein
CFN49_RS02815	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
CFN49_RS02815	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CFN49_RS02820	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
CFN49_RS02820	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CFN49_RS02825	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CFN49_RS02835	COG0439	Biotin carboxylase
CFN49_RS02845	COG0825	malonyl-CoA metabolic process
CFN49_RS02850	COG1316	TRANSCRIPTIONal
CFN49_RS02860	COG0697	spore germination
CFN49_RS02865	COG0588	phosphoglycerate mutase activity
CFN49_RS02885	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
CFN49_RS02895	COG0756	dUTP diphosphatase activity
CFN49_RS02915	COG4956	integral membrane protein (PIN domain superfamily)
CFN49_RS02920	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CFN49_RS02925	COG0215	cysteine-tRNA ligase activity
CFN49_RS02930	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
CFN49_RS02935	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CFN49_RS02950	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CFN49_RS02960	COG0250	Participates in transcription elongation, termination and antitermination
CFN49_RS02970	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
CFN49_RS02975	COG0081	regulation of translation
CFN49_RS02980	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
CFN49_RS02985	COG0222	ribosome binding
CFN49_RS03005	COG1611	Belongs to the LOG family
CFN49_RS03015	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CFN49_RS03020	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CFN49_RS03025	COG2813	Specifically methylates the guanine in position
CFN49_RS03040	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CFN49_RS03045	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
CFN49_RS03050	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
CFN49_RS03060	COG3711	transcriptional antiterminator
CFN49_RS03085	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
CFN49_RS03090	COG3870	Protein conserved in bacteria
CFN49_RS03095	COG0470	DNA polymerase III
CFN49_RS03100	COG4467	Involved in initiation control of chromosome replication
CFN49_RS03115	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CFN49_RS03120	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
CFN49_RS03125	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CFN49_RS03130	COG3639	organic phosphonate transmembrane transporter activity
CFN49_RS03140	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
CFN49_RS03150	COG1214	PFAM Peptidase M22, glycoprotease
CFN49_RS03155	COG0456	acetyltransferase
CFN49_RS03160	COG0456	acetyltransferase
CFN49_RS03165	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
CFN49_RS03175	COG0488	(ABC) transporter
CFN49_RS03180	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
CFN49_RS03195	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
CFN49_RS03200	COG0459	protein refolding
CFN49_RS03205	COG0531	amino acid
CFN49_RS03210	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CFN49_RS03215	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
CFN49_RS03220	COG1739	Uncharacterized protein family UPF0029
CFN49_RS03225	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
CFN49_RS03240	COG0653	protein targeting
CFN49_RS03255	COG0745	RESPONSE REGULATOR receiver
CFN49_RS03260	COG5002	protein histidine kinase activity
CFN49_RS03270	COG0573	inorganic phosphate transmembrane transporter activity
CFN49_RS03275	COG0581	inorganic phosphate transmembrane transporter activity
CFN49_RS03280	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CFN49_RS03285	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CFN49_RS03290	COG0704	Plays a role in the regulation of phosphate uptake
CFN49_RS03295	COG1983	PspC domain protein
CFN49_RS03300	COG1950	PFAM Membrane protein of
CFN49_RS03305	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
CFN49_RS03310	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
CFN49_RS03315	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
CFN49_RS03320	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CFN49_RS03330	COG0446	pyridine nucleotide-disulphide oxidoreductase
CFN49_RS03350	COG1215	transferase activity, transferring glycosyl groups
CFN49_RS03365	COG0492	ferredoxin-NADP+ reductase activity
CFN49_RS03370	COG2323	membrane
CFN49_RS03380	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CFN49_RS03390	COG0446	pyridine nucleotide-disulphide oxidoreductase
CFN49_RS03400	COG2814	Major facilitator Superfamily
CFN49_RS03410	COG0556	nucleotide-excision repair
CFN49_RS03415	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CFN49_RS03420	COG1854	S-ribosylhomocysteine lyase activity
CFN49_RS03425	COG0137	argininosuccinate synthase activity
CFN49_RS03430	COG0165	Argininosuccinate lyase
CFN49_RS03440	COG1660	Displays ATPase and GTPase activities
CFN49_RS03450	COG1481	regulation of sporulation
CFN49_RS03460	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CFN49_RS03465	COG0740	serine-type endopeptidase activity
CFN49_RS03475	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
CFN49_RS03480	COG2390	Transcriptional regulator
CFN49_RS03490	COG0126	phosphoglycerate kinase activity
CFN49_RS03495	COG0149	triose-phosphate isomerase activity
CFN49_RS03500	COG0148	phosphopyruvate hydratase activity
CFN49_RS03515	COG0038	chloride channel
CFN49_RS03520	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CFN49_RS03530	COG0557	exoribonuclease II activity
CFN49_RS03535	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
CFN49_RS03545	COG0765	amino acid transport
CFN49_RS03550	COG1126	abc transporter atp-binding protein
CFN49_RS03560	COG0561	phosphatase activity
CFN49_RS03565	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
CFN49_RS03570	COG0280	phosphate acetyltransferase
CFN49_RS03575	COG0802	atpase or kinase
CFN49_RS03590	COG0708	Exodeoxyribonuclease III
CFN49_RS03600	COG0812	UDP-N-acetylmuramate dehydrogenase activity
CFN49_RS03605	COG0025	NhaP-type Na H and K H
CFN49_RS03630	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CFN49_RS03635	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CFN49_RS03645	COG0561	phosphatase activity
CFN49_RS03655	COG2017	converts alpha-aldose to the beta-anomer
CFN49_RS03670	COG0778	Nitroreductase
CFN49_RS03690	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CFN49_RS03705	COG1393	Belongs to the ArsC family
CFN49_RS03720	COG0477	Major facilitator Superfamily
CFN49_RS03725	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
CFN49_RS03725	COG0248	Ppx GppA phosphatase
CFN49_RS03730	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
CFN49_RS03740	COG3475	LICD family
CFN49_RS03755	COG2252	PERMEase
CFN49_RS03760	COG0028	Belongs to the TPP enzyme family
CFN49_RS03765	COG0196	riboflavin kinase activity
CFN49_RS03770	COG0028	Belongs to the TPP enzyme family
CFN49_RS03775	COG2267	carboxylic ester hydrolase activity
CFN49_RS03785	COG2755	lipolytic protein G-D-S-L family
CFN49_RS03785	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
CFN49_RS03790	COG2936	dipeptidyl-peptidase activity
CFN49_RS03805	COG0531	amino acid
CFN49_RS03830	COG0194	GDP metabolic process
CFN49_RS03835	COG0735	belongs to the Fur family
CFN49_RS03850	COG0546	phosphoglycolate phosphatase activity
CFN49_RS03860	COG0436	Aminotransferase
CFN49_RS03865	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CFN49_RS03885	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CFN49_RS03890	COG0765	amino acid transport
CFN49_RS03895	COG0765	amino acid transport
CFN49_RS03900	COG2190	(PTS) system
CFN49_RS03900	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CFN49_RS03900	COG1263	PTS System
CFN49_RS03910	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CFN49_RS03910	COG1263	PTS System
CFN49_RS03915	COG3394	polysaccharide catabolic process
CFN49_RS03920	COG0531	amino acid
CFN49_RS03930	COG1846	Transcriptional regulator
CFN49_RS03960	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CFN49_RS03970	COG2076	Multidrug Resistance protein
CFN49_RS03985	COG0588	phosphoglycerate mutase activity
CFN49_RS03990	COG0475	glutathione-regulated potassium exporter activity
CFN49_RS03990	COG0569	domain protein
CFN49_RS03995	COG0456	acetyltransferase
CFN49_RS03995	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
CFN49_RS04000	COG0586	Pfam SNARE associated Golgi protein
CFN49_RS04005	COG3973	AAA domain
CFN49_RS04010	COG2070	2-Nitropropane dioxygenase
CFN49_RS04015	COG1072	(Pantothenic acid kinase))
CFN49_RS04020	COG0519	Catalyzes the synthesis of GMP from XMP
CFN49_RS04020	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CFN49_RS04030	COG1396	sequence-specific DNA binding
CFN49_RS04040	COG1266	CAAX protease self-immunity
CFN49_RS04080	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
CFN49_RS04080	COG2755	lipolytic protein G-D-S-L family
CFN49_RS04085	COG2261	transglycosylase associated protein
CFN49_RS04100	COG1302	Protein conserved in bacteria
CFN49_RS04130	COG0308	aminopeptidase N
CFN49_RS04160	COG0572	uridine kinase
CFN49_RS04175	COG0583	DNA-binding transcription factor activity
CFN49_RS04180	COG1053	succinate dehydrogenase
CFN49_RS04190	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
CFN49_RS04195	COG0017	Asparaginyl-tRNA synthetase
CFN49_RS04200	COG2502	aspartate--ammonia ligase
CFN49_RS04205	COG4690	dipeptidase activity
CFN49_RS04225	COG0514	ATP-dependent DNA helicase (RecQ)
CFN49_RS04230	COG0564	pseudouridine synthase activity
CFN49_RS04235	COG0640	Transcriptional regulator
CFN49_RS04285	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CFN49_RS04290	COG0527	aspartate kinase activity
CFN49_RS04295	COG0367	asparagine synthase
CFN49_RS04350	COG2814	Major facilitator Superfamily
CFN49_RS04370	COG1278	Cold shock
CFN49_RS04375	COG2966	Psort location CytoplasmicMembrane, score
CFN49_RS04385	COG1316	TRANSCRIPTIONal
CFN49_RS04405	COG1959	2 iron, 2 sulfur cluster binding
CFN49_RS04410	COG0028	Belongs to the TPP enzyme family
CFN49_RS04415	COG0833	amino acid
CFN49_RS04425	COG1428	Deoxynucleoside kinase
CFN49_RS04430	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
CFN49_RS04470	COG4463	regulation of RNA biosynthetic process
CFN49_RS04475	COG0542	response to heat
CFN49_RS04485	COG0085	RNA polymerase activity
CFN49_RS04490	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CFN49_RS04495	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
CFN49_RS04500	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
CFN49_RS04505	COG0049	tRNA binding
CFN49_RS04510	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CFN49_RS04515	COG0051	transcription antitermination factor activity, RNA binding
CFN49_RS04520	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
CFN49_RS04525	COG0088	Forms part of the polypeptide exit tunnel
CFN49_RS04530	COG0089	rRNA binding
CFN49_RS04535	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
CFN49_RS04540	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
CFN49_RS04545	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
CFN49_RS04550	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
CFN49_RS04555	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
CFN49_RS04560	COG0255	Belongs to the universal ribosomal protein uL29 family
CFN49_RS04565	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
CFN49_RS04570	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
CFN49_RS04575	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
CFN49_RS04580	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
CFN49_RS04585	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
CFN49_RS04590	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
CFN49_RS04595	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
CFN49_RS04600	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
CFN49_RS04605	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
CFN49_RS04610	COG1841	ribosomal large subunit assembly
CFN49_RS04615	COG0200	Binds to the 23S rRNA
CFN49_RS04625	COG0563	adenylate kinase activity
CFN49_RS04630	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
CFN49_RS04635	COG0257	Belongs to the bacterial ribosomal protein bL36 family
CFN49_RS04640	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
CFN49_RS04645	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
CFN49_RS04650	COG0202	RNA polymerase activity
CFN49_RS04655	COG0203	ribosomal protein L17
CFN49_RS04680	COG4939	FMN-binding domain protein
CFN49_RS04690	COG1122	ATPase activity
CFN49_RS04695	COG1122	ATPase activity
CFN49_RS04705	COG0101	tRNA pseudouridine synthase activity
CFN49_RS04710	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
CFN49_RS04715	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
CFN49_RS04735	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CFN49_RS04740	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CFN49_RS04745	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
CFN49_RS04750	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
CFN49_RS04755	COG0471	metal ion transport
CFN49_RS04760	COG2151	metal-sulfur cluster biosynthetic enzyme
CFN49_RS04765	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
CFN49_RS04775	COG1917	Cupin 2, conserved barrel domain protein
CFN49_RS04775	COG4977	sequence-specific DNA binding
CFN49_RS04780	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
CFN49_RS04785	COG1121	(ABC) transporter
CFN49_RS04790	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CFN49_RS04795	COG0803	Belongs to the bacterial solute-binding protein 9 family
CFN49_RS04805	COG0039	L-malate dehydrogenase activity
CFN49_RS04810	COG0471	metal ion transport
CFN49_RS04830	COG3052	prosthetic group binding
CFN49_RS04845	COG2826	transposase and inactivated derivatives, IS30 family
CFN49_RS04870	COG0114	fumarate hydratase activity
CFN49_RS04875	COG1053	succinate dehydrogenase
CFN49_RS04885	COG0583	DNA-binding transcription factor activity
CFN49_RS04890	COG0583	DNA-binding transcription factor activity
CFN49_RS04895	COG0281	malic enzyme
CFN49_RS04905	COG0531	amino acid
CFN49_RS04910	COG4684	Psort location CytoplasmicMembrane, score
CFN49_RS04925	COG1271	oxidase subunit
CFN49_RS04930	COG1294	oxidase, subunit
CFN49_RS04935	COG4988	ABC transporter
CFN49_RS04940	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
CFN49_RS04955	COG0142	geranyltranstransferase activity
CFN49_RS04970	COG1705	Flagellar rod assembly protein muramidase FlgJ
CFN49_RS04975	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CFN49_RS04980	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
CFN49_RS04985	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
CFN49_RS04995	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CFN49_RS05000	COG4851	CamS sex pheromone cAM373 precursor
CFN49_RS05005	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CFN49_RS05010	COG0154	amidase activity
CFN49_RS05015	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CFN49_RS05020	COG1597	lipid kinase activity
CFN49_RS05025	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CFN49_RS05040	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CFN49_RS05050	COG1737	Transcriptional regulator
CFN49_RS05065	COG1278	Cold shock
CFN49_RS05070	COG0673	inositol 2-dehydrogenase activity
CFN49_RS05075	COG0513	Belongs to the DEAD box helicase family
CFN49_RS05090	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CFN49_RS05115	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CFN49_RS05125	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
CFN49_RS05135	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
CFN49_RS05140	COG0562	UDP-galactopyranose mutase
CFN49_RS05180	COG1216	Glycosyl transferase, family 2
CFN49_RS05190	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
CFN49_RS05195	COG1215	transferase activity, transferring glycosyl groups
CFN49_RS05220	COG1088	dTDP-glucose 4,6-dehydratase activity
CFN49_RS05225	COG1091	dTDP-4-dehydrorhamnose reductase activity
CFN49_RS05230	COG0582	viral genome integration into host DNA
CFN49_RS05240	COG0489	protein tyrosine kinase activity
CFN49_RS05245	COG4464	protein tyrosine phosphatase activity
CFN49_RS05250	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CFN49_RS05255	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CFN49_RS05260	COG0463	Glycosyl transferase, family 2
CFN49_RS05265	COG0438	transferase activity, transferring glycosyl groups
CFN49_RS05275	COG0438	transferase activity, transferring glycosyl groups
CFN49_RS05280	COG0438	transferase activity, transferring glycosyl groups
CFN49_RS05310	COG0562	UDP-galactopyranose mutase
CFN49_RS05345	COG2207	Transcriptional regulator
CFN49_RS05345	COG1609	Transcriptional regulator
CFN49_RS05365	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CFN49_RS05400	COG2137	regulation of response to DNA damage stimulus
CFN49_RS05405	COG3557	Belongs to the UPF0374 family
CFN49_RS05425	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CFN49_RS05435	COG0628	permease
CFN49_RS05440	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
CFN49_RS05445	COG2610	gluconate transmembrane transporter activity
CFN49_RS05450	COG1070	Carbohydrate kinase
CFN49_RS05455	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
CFN49_RS05460	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CFN49_RS05465	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
CFN49_RS05495	COG4166	transmembrane transport
CFN49_RS05500	COG0601	transmembrane transport
CFN49_RS05505	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CFN49_RS05510	COG0444	Belongs to the ABC transporter superfamily
CFN49_RS05515	COG4608	Belongs to the ABC transporter superfamily
CFN49_RS05525	COG0582	viral genome integration into host DNA
CFN49_RS05530	COG0542	response to heat
CFN49_RS05550	COG0438	transferase activity, transferring glycosyl groups
CFN49_RS05555	COG0438	transferase activity, transferring glycosyl groups
CFN49_RS05565	COG1686	Belongs to the peptidase S11 family
CFN49_RS05570	COG0436	Aminotransferase
CFN49_RS05575	COG4703	Protein of unknown function (DUF1797)
CFN49_RS05580	COG1368	sulfuric ester hydrolase activity
CFN49_RS05670	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CFN49_RS05690	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
CFN49_RS05705	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
CFN49_RS05710	COG0833	amino acid
CFN49_RS05715	COG2040	homocysteine
CFN49_RS05720	COG0438	transferase activity, transferring glycosyl groups
CFN49_RS05730	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
CFN49_RS05735	COG0477	Major facilitator Superfamily
CFN49_RS05750	COG0438	transferase activity, transferring glycosyl groups
CFN49_RS05765	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
CFN49_RS05775	COG0495	leucyl-tRNA aminoacylation
CFN49_RS05780	COG2244	polysaccharide biosynthetic process
CFN49_RS05785	COG1187	pseudouridine synthase activity
CFN49_RS05790	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
CFN49_RS05795	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CFN49_RS05805	COG3842	ATPase activity
CFN49_RS05810	COG1175	transmembrane transport
CFN49_RS05815	COG0395	ABC-type sugar transport system, permease component
CFN49_RS05825	COG0584	glycerophosphoryl diester phosphodiesterase
CFN49_RS05830	COG1428	Deoxynucleoside kinase
CFN49_RS05835	COG1970	mechanosensitive ion channel activity
CFN49_RS05840	COG1511	domain protein
CFN49_RS05840	COG1511	domain protein
CFN49_RS05870	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CFN49_RS05885	COG0697	spore germination
CFN49_RS05890	COG0561	phosphatase activity
CFN49_RS05910	COG3279	Response regulator of the LytR AlgR family
CFN49_RS05930	COG1846	Transcriptional regulator
CFN49_RS05945	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CFN49_RS05985	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
CFN49_RS05985	COG0646	methionine synthase
CFN49_RS05990	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
CFN49_RS06000	COG2046	Belongs to the sulfate adenylyltransferase family
CFN49_RS06005	COG0529	Catalyzes the synthesis of activated sulfate
CFN49_RS06010	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
CFN49_RS06020	COG3273	potassium ion transport
CFN49_RS06020	COG0471	metal ion transport
CFN49_RS06025	COG0534	Mate efflux family protein
CFN49_RS06045	COG2153	protein acetylation
CFN49_RS06050	COG0018	arginyl-trna synthetase
CFN49_RS06060	COG1136	(ABC) transporter
CFN49_RS06060	COG0577	efflux transmembrane transporter activity
CFN49_RS06080	COG1447	Phosphotransferase system cellobiose-specific component IIA
CFN49_RS06085	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CFN49_RS06090	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CFN49_RS06095	COG2723	6-phospho-beta-galactosidase activity
CFN49_RS06105	COG1376	ErfK ybiS ycfS ynhG family protein
CFN49_RS06110	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CFN49_RS06115	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CFN49_RS06125	COG0436	Aminotransferase
CFN49_RS06130	COG1438	arginine binding
CFN49_RS06140	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CFN49_RS06145	COG3679	Belongs to the UPF0342 family
CFN49_RS06150	COG0420	3'-5' exonuclease activity
CFN49_RS06155	COG4717	serine-type aminopeptidase activity
CFN49_RS06160	COG3481	metal-dependent phosphohydrolase, HD sub domain
CFN49_RS06175	COG0583	DNA-binding transcription factor activity
CFN49_RS06185	COG1053	succinate dehydrogenase
CFN49_RS06185	COG3976	FMN-binding domain protein
CFN49_RS06185	COG0431	NADPH-dependent FMN reductase
CFN49_RS06230	COG2217	Heavy metal translocating P-type atpase
CFN49_RS06235	COG0148	phosphopyruvate hydratase activity
CFN49_RS06245	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
CFN49_RS06255	COG0463	Glycosyl transferase, family 2
CFN49_RS06275	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CFN49_RS06275	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CFN49_RS06280	COG0307	riboflavin synthase, alpha
CFN49_RS06285	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CFN49_RS06285	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CFN49_RS06290	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
CFN49_RS06305	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CFN49_RS06315	COG0446	pyridine nucleotide-disulphide oxidoreductase
CFN49_RS06345	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CFN49_RS06355	COG0537	adenosine 5'-monophosphoramidase activity
CFN49_RS06360	COG1131	(ABC) transporter
CFN49_RS06365	COG4473	ABC transporter
CFN49_RS06370	COG0510	thiamine kinase activity
CFN49_RS06375	COG0220	tRNA (guanine-N7-)-methyltransferase activity
CFN49_RS06385	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CFN49_RS06390	COG1674	ftsk spoiiie
CFN49_RS06395	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CFN49_RS06420	COG0719	Fe-S assembly protein
CFN49_RS06425	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CFN49_RS06435	COG0719	Fe-S assembly protein
CFN49_RS06440	COG2151	metal-sulfur cluster biosynthetic enzyme
CFN49_RS06455	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CFN49_RS06455	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CFN49_RS06460	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
CFN49_RS06465	COG0237	dephospho-CoA kinase activity
CFN49_RS06470	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
CFN49_RS06475	COG3611	Membrane attachment protein
CFN49_RS06480	COG1484	DNA-dependent DNA replication
CFN49_RS06485	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
CFN49_RS06490	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
CFN49_RS06495	COG0291	Belongs to the bacterial ribosomal protein bL35 family
CFN49_RS06500	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
CFN49_RS06510	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CFN49_RS06515	COG0604	alcohol dehydrogenase
CFN49_RS06520	COG1733	regulation of RNA biosynthetic process
CFN49_RS06530	COG1215	transferase activity, transferring glycosyl groups
CFN49_RS06545	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
CFN49_RS06550	COG1534	Rna-binding protein
CFN49_RS06555	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
CFN49_RS06560	COG1713	HD superfamily hydrolase involved in NAD metabolism
CFN49_RS06565	COG0799	negative regulation of ribosome biogenesis
CFN49_RS06570	COG2226	methyltransferase
CFN49_RS06575	COG1323	Belongs to the UPF0348 family
CFN49_RS06585	COG0333	Belongs to the bacterial ribosomal protein bL32 family
CFN49_RS06600	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
CFN49_RS06605	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CFN49_RS06610	COG0745	RESPONSE REGULATOR receiver
CFN49_RS06615	COG5002	protein histidine kinase activity
CFN49_RS06625	COG0419	ATPase involved in DNA repair
CFN49_RS06640	COG0706	membrane insertase activity
CFN49_RS06645	COG1254	Belongs to the acylphosphatase family
CFN49_RS06650	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CFN49_RS06660	COG1733	regulation of RNA biosynthetic process
CFN49_RS06665	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
CFN49_RS06670	COG0072	phenylalanine-tRNA ligase activity
CFN49_RS06670	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CFN49_RS06675	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CFN49_RS06680	COG0572	uridine kinase
CFN49_RS06685	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CFN49_RS06700	COG4841	protein insertion into membrane
CFN49_RS06710	COG0768	penicillin binding
CFN49_RS06715	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CFN49_RS06720	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
CFN49_RS06725	COG0705	Rhomboid family
CFN49_RS06725	COG0457	Tetratricopeptide repeat
CFN49_RS06735	COG1940	carbohydrate kinase activity
CFN49_RS06755	COG0584	glycerophosphoryl diester phosphodiesterase
CFN49_RS06760	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
CFN49_RS06765	COG0789	Transcriptional regulator
CFN49_RS06815	COG0261	This protein binds to 23S rRNA in the presence of protein L20
CFN49_RS06825	COG0211	Belongs to the bacterial ribosomal protein bL27 family
CFN49_RS06830	COG0006	proline dipeptidase activity
CFN49_RS06835	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
CFN49_RS06840	COG1302	Protein conserved in bacteria
CFN49_RS06845	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CFN49_RS06850	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
CFN49_RS06855	COG1570	exodeoxyribonuclease VII activity
CFN49_RS06860	COG1722	exodeoxyribonuclease VII activity
CFN49_RS06865	COG0142	geranyltranstransferase activity
CFN49_RS06870	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
CFN49_RS06875	COG1438	arginine binding
CFN49_RS06880	COG0497	DNA recombination
CFN49_RS06895	COG1732	Glycine betaine
CFN49_RS06910	COG0194	GDP metabolic process
CFN49_RS06915	COG1758	RNA polymerase activity
CFN49_RS06920	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CFN49_RS06925	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CFN49_RS06930	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CFN49_RS06935	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CFN49_RS06935	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CFN49_RS06940	COG0631	protein serine/threonine phosphatase activity
CFN49_RS06945	COG0515	serine threonine protein kinase
CFN49_RS06945	COG2815	serine threonine protein kinase
CFN49_RS06950	COG1162	GTPase activity
CFN49_RS06955	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CFN49_RS06960	COG1564	THIamine pyrophosphokinase
CFN49_RS06970	COG0227	Belongs to the bacterial ribosomal protein bL28 family
CFN49_RS06975	COG1302	Protein conserved in bacteria
CFN49_RS06980	COG1461	Dihydroxyacetone kinase
CFN49_RS06985	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CFN49_RS06990	COG0416	fatty acid biosynthetic process
CFN49_RS06995	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CFN49_RS07000	COG0571	ribonuclease III activity
CFN49_RS07005	COG1196	nuclear chromosome segregation
CFN49_RS07010	COG0552	protein localization to endoplasmic reticulum
CFN49_RS07015	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
CFN49_RS07020	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CFN49_RS07025	COG0228	four-way junction DNA binding
CFN49_RS07030	COG1837	Belongs to the UPF0109 family
CFN49_RS07035	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
CFN49_RS07040	COG0336	Belongs to the RNA methyltransferase TrmD family
CFN49_RS07045	COG0335	large ribosomal subunit rRNA binding
CFN49_RS07080	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CFN49_RS07080	COG0512	Glutamine amidotransferase of anthranilate synthase
CFN49_RS07085	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CFN49_RS07090	COG0134	indole-3-glycerol-phosphate synthase activity
CFN49_RS07095	COG0135	phosphoribosylanthranilate isomerase activity
CFN49_RS07100	COG0133	tryptophan synthase activity
CFN49_RS07105	COG0159	tryptophan synthase activity
CFN49_RS07120	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CFN49_RS07130	COG1473	amidohydrolase
CFN49_RS07135	COG1063	alcohol dehydrogenase
CFN49_RS07145	COG0300	oxidoreductase activity
CFN49_RS07155	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CFN49_RS07160	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CFN49_RS07165	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CFN49_RS07170	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
CFN49_RS07175	COG1028	Short-chain dehydrogenase reductase Sdr
CFN49_RS07180	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CFN49_RS07190	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CFN49_RS07195	COG0439	Biotin carboxylase
CFN49_RS07210	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
CFN49_RS07220	COG1811	Na channel or pump
CFN49_RS07225	COG0583	DNA-binding transcription factor activity
CFN49_RS07230	COG1607	acyl-coa hydrolase
CFN49_RS07235	COG1162	GTPase activity
CFN49_RS07245	COG0477	Major facilitator Superfamily
CFN49_RS07280	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CFN49_RS07285	COG3397	chitin binding
CFN49_RS07300	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
CFN49_RS07310	COG3152	Membrane
CFN49_RS07315	COG1597	lipid kinase activity
CFN49_RS07330	COG2261	transglycosylase associated protein
CFN49_RS07335	COG3237	CsbD-like
CFN49_RS07350	COG1942	4-Oxalocrotonate Tautomerase
CFN49_RS07390	COG0531	amino acid
CFN49_RS07395	COG0561	phosphatase activity
CFN49_RS07400	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
CFN49_RS07400	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CFN49_RS07420	COG2017	converts alpha-aldose to the beta-anomer
CFN49_RS07425	COG1304	FMN binding
CFN49_RS07450	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CFN49_RS07450	COG1199	ATP-dependent helicase activity
CFN49_RS07465	COG0017	Asparaginyl-tRNA synthetase
CFN49_RS07480	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CFN49_RS07485	COG2011	ABC-type metal ion transport system permease component
CFN49_RS07490	COG1464	Belongs to the NlpA lipoprotein family
CFN49_RS07500	COG1177	transmembrane transport
CFN49_RS07505	COG1840	ABC-type Fe3 transport system, periplasmic component
CFN49_RS07520	COG3331	DNA recombination
CFN49_RS07525	COG4474	Belongs to the UPF0398 family
CFN49_RS07530	COG3599	regulation of cell shape
CFN49_RS07540	COG0116	Belongs to the methyltransferase superfamily
CFN49_RS07550	COG0477	Major facilitator Superfamily
CFN49_RS07555	COG1073	alpha beta
CFN49_RS07585	COG1619	proteins homologs of microcin C7 resistance protein MccF
CFN49_RS07615	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CFN49_RS07630	COG2759	Belongs to the formate--tetrahydrofolate ligase family
CFN49_RS07635	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
CFN49_RS07640	COG0564	pseudouridine synthase activity
CFN49_RS07645	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
CFN49_RS07650	COG0505	Belongs to the CarA family
CFN49_RS07655	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
CFN49_RS07670	COG5646	InterPro IPR014922
CFN49_RS07695	COG1131	(ABC) transporter
CFN49_RS07700	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
CFN49_RS07705	COG1293	RNA-binding protein homologous to eukaryotic snRNP
CFN49_RS07715	COG1307	EDD domain protein, DegV family
CFN49_RS07775	COG1113	amino acid transport
CFN49_RS07790	COG1620	l-lactate permease
CFN49_RS07800	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
CFN49_RS07825	COG1846	Transcriptional regulator
CFN49_RS07830	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CFN49_RS07865	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CFN49_RS07870	COG1227	inorganic diphosphatase activity
CFN49_RS07875	COG0583	DNA-binding transcription factor activity
CFN49_RS07885	COG0187	DNA topoisomerase II activity
CFN49_RS07890	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
CFN49_RS07900	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
CFN49_RS07905	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
CFN49_RS07910	COG4974	Belongs to the 'phage' integrase family
CFN49_RS07915	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
CFN49_RS07920	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CFN49_RS07925	COG0758	DNA mediated transformation
CFN49_RS07930	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CFN49_RS07935	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
CFN49_RS07945	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
CFN49_RS07950	COG0583	DNA-binding transcription factor activity
CFN49_RS07980	COG2814	Major facilitator Superfamily
CFN49_RS07985	COG3409	Peptidoglycan-binding domain 1 protein
CFN49_RS07985	COG0793	Belongs to the peptidase S41A family
CFN49_RS07990	COG4479	Belongs to the UPF0346 family
CFN49_RS07995	COG4698	Protein conserved in bacteria
CFN49_RS08000	COG2755	lipolytic protein G-D-S-L family
CFN49_RS08005	COG1307	EDD domain protein, DegV family
CFN49_RS08010	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
CFN49_RS08015	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
CFN49_RS08020	COG0488	(ABC) transporter
CFN49_RS08030	COG0617	tRNA 3'-terminal CCA addition
CFN49_RS08035	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
CFN49_RS08040	COG0561	phosphatase activity
CFN49_RS08045	COG0457	Tetratricopeptide repeat
CFN49_RS08060	COG1160	GTP binding
CFN49_RS08065	COG0539	negative regulation of cytoplasmic translation
CFN49_RS08070	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
CFN49_RS08080	COG0514	ATP-dependent DNA helicase (RecQ)
CFN49_RS08090	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
CFN49_RS08095	COG1187	pseudouridine synthase activity
CFN49_RS08100	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
CFN49_RS08105	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
CFN49_RS08115	COG4974	Belongs to the 'phage' integrase family
CFN49_RS08120	COG2996	Protein conserved in bacteria
CFN49_RS08140	COG0205	6-phosphofructokinase activity
CFN49_RS08145	COG0587	DNA-directed DNA polymerase activity
CFN49_RS08155	COG0542	response to heat
CFN49_RS08165	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
CFN49_RS08170	COG2384	SAM-dependent methyltransferase
CFN49_RS08195	COG0574	Belongs to the PEP-utilizing enzyme family
CFN49_RS08195	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CFN49_RS08205	COG1846	Transcriptional regulator
CFN49_RS08225	COG2217	Heavy metal translocating P-type atpase
CFN49_RS08230	COG0148	phosphopyruvate hydratase activity
CFN49_RS08235	COG0477	Major facilitator Superfamily
CFN49_RS08245	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CFN49_RS08250	COG0446	pyridine nucleotide-disulphide oxidoreductase
CFN49_RS08255	COG1349	DNA-binding transcription factor activity
CFN49_RS08285	COG0546	phosphoglycolate phosphatase activity
CFN49_RS08315	COG0583	DNA-binding transcription factor activity
CFN49_RS08320	COG0604	alcohol dehydrogenase
CFN49_RS08330	COG0446	pyridine nucleotide-disulphide oxidoreductase
CFN49_RS08335	COG2197	response regulator
CFN49_RS08340	COG4585	Histidine kinase
CFN49_RS08350	COG1131	(ABC) transporter
CFN49_RS08360	COG0519	Catalyzes the synthesis of GMP from XMP
CFN49_RS08375	COG1131	(ABC) transporter
CFN49_RS08395	COG1131	(ABC) transporter
CFN49_RS08400	COG1725	Transcriptional regulator
CFN49_RS08410	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CFN49_RS08415	COG0358	DNA primase activity
CFN49_RS08420	COG0751	glycine-tRNA ligase activity
CFN49_RS08425	COG0752	glycyl-tRNA synthetase alpha subunit
CFN49_RS08430	COG1381	Involved in DNA repair and RecF pathway recombination
CFN49_RS08435	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
CFN49_RS08440	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
CFN49_RS08445	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
CFN49_RS08450	COG1702	phosphate starvation-inducible protein PhoH
CFN49_RS08455	COG1610	YqeY-like protein
CFN49_RS08460	COG0828	Belongs to the bacterial ribosomal protein bS21 family
CFN49_RS08465	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
CFN49_RS08475	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
CFN49_RS08485	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CFN49_RS08495	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
CFN49_RS08500	COG0124	histidyl-tRNA synthetase
CFN49_RS08505	COG3103	Sh3 type 3 domain protein
CFN49_RS08505	COG0860	N-Acetylmuramoyl-L-alanine amidase
CFN49_RS08505	COG4991	sh3 domain protein
CFN49_RS08510	COG3001	Fructosamine kinase
CFN49_RS08515	COG0546	phosphoglycolate phosphatase activity
CFN49_RS08520	COG1490	D-aminoacyl-tRNA deacylase activity
CFN49_RS08525	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CFN49_RS08535	COG1385	rRNA (uridine-N3-)-methyltransferase activity
CFN49_RS08540	COG2264	protein methyltransferase activity
CFN49_RS08545	COG2094	Belongs to the DNA glycosylase MPG family
CFN49_RS08570	COG0582	viral genome integration into host DNA
CFN49_RS08575	COG0481	GTPase activity
CFN49_RS08580	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
CFN49_RS08585	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CFN49_RS08590	COG1696	Membrane protein involved in D-alanine export
CFN49_RS08595	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CFN49_RS08605	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CFN49_RS08610	COG0484	heat shock protein binding
CFN49_RS08615	COG0443	Heat shock 70 kDa protein
CFN49_RS08620	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
CFN49_RS08625	COG1420	regulation of RNA biosynthetic process
CFN49_RS08630	COG3527	Alpha-acetolactate decarboxylase
CFN49_RS08635	COG0196	riboflavin kinase activity
CFN49_RS08640	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
CFN49_RS08645	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
CFN49_RS08650	COG0287	Prephenate dehydrogenase
CFN49_RS08655	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
CFN49_RS08665	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
CFN49_RS08670	COG0738	Major facilitator superfamily
CFN49_RS08675	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
CFN49_RS08680	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
CFN49_RS08690	COG2740	Nucleic-acid-binding protein implicated in transcription termination
CFN49_RS08695	COG0195	Participates in both transcription termination and antitermination
CFN49_RS08700	COG0779	Required for maturation of 30S ribosomal subunits
CFN49_RS08705	COG2176	DNA-directed DNA polymerase activity
CFN49_RS08710	COG0442	prolyl-tRNA aminoacylation
CFN49_RS08715	COG0750	zinc metalloprotease
CFN49_RS08720	COG4589	Belongs to the CDS family
CFN49_RS08725	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CFN49_RS08730	COG0233	cytoplasmic translational termination
CFN49_RS08735	COG0528	UMP kinase activity
CFN49_RS08740	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
CFN49_RS08745	COG0052	Belongs to the universal ribosomal protein uS2 family
CFN49_RS08755	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CFN49_RS08760	COG2827	Endonuclease containing a URI domain
CFN49_RS08765	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
CFN49_RS08770	COG0204	Acyl-transferase
CFN49_RS08775	COG3763	UPF0154 protein
CFN49_RS08780	COG4224	UPF0291 protein
CFN49_RS08785	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CFN49_RS08800	COG3425	synthase
CFN49_RS08815	COG0463	Glycosyl transferase, family 2
CFN49_RS08825	COG1316	TRANSCRIPTIONal
CFN49_RS08830	COG1116	anion transmembrane transporter activity
CFN49_RS08840	COG0772	Belongs to the SEDS family
CFN49_RS09000	COG0629	single-stranded DNA binding
CFN49_RS09065	COG1396	sequence-specific DNA binding
CFN49_RS09120	COG0393	Putative heavy-metal-binding
CFN49_RS09135	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CFN49_RS09140	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
CFN49_RS09140	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
CFN49_RS09145	COG5416	Lipopolysaccharide assembly protein A domain
CFN49_RS09150	COG0300	oxidoreductase activity
CFN49_RS09155	COG1234	tRNA 3'-trailer cleavage
CFN49_RS09165	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
CFN49_RS09170	COG1349	DNA-binding transcription factor activity
CFN49_RS09175	COG1105	Belongs to the carbohydrate kinase PfkB family
CFN49_RS09180	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CFN49_RS09180	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CFN49_RS09180	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CFN49_RS09185	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
CFN49_RS09210	COG0297	glycogen (starch) synthase activity
CFN49_RS09215	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CFN49_RS09220	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CFN49_RS09230	COG0489	protein tyrosine kinase activity
CFN49_RS09240	COG0322	excinuclease ABC activity
CFN49_RS09245	COG1126	abc transporter atp-binding protein
CFN49_RS09250	COG0765	amino acid transport
CFN49_RS09270	COG0218	Necessary for normal cell division and for the maintenance of normal septation
CFN49_RS09275	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
CFN49_RS09280	COG0544	peptidyl-prolyl cis-trans isomerase activity
CFN49_RS09285	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CFN49_RS09310	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
CFN49_RS09315	COG0268	Binds directly to 16S ribosomal RNA
CFN49_RS09320	COG1466	dna polymerase III delta subunit
CFN49_RS09325	COG0658	competence protein
CFN49_RS09325	COG2333	competence protein COMEC
CFN49_RS09330	COG2131	deaminase
CFN49_RS09335	COG1555	photosystem II stabilization
CFN49_RS09335	COG1596	polysaccharide export
CFN49_RS09340	COG3480	Lon protease (S16) C-terminal proteolytic domain
CFN49_RS09345	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
CFN49_RS09350	COG0742	ribosomal rna small subunit methyltransferase
CFN49_RS09355	COG4471	UPF0298 protein
CFN49_RS09360	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
CFN49_RS09365	COG0772	Belongs to the SEDS family
CFN49_RS09400	COG1217	gtp-binding protein TYPA
CFN49_RS09405	COG0483	inositol monophosphate 1-phosphatase activity
CFN49_RS09410	COG4476	Belongs to the UPF0223 family
CFN49_RS09415	COG0039	L-malate dehydrogenase activity
CFN49_RS09440	COG0242	peptide deformylase activity
CFN49_RS09450	COG5503	Protein of unknown function (DUF1447)
CFN49_RS09455	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
CFN49_RS09460	COG1597	lipid kinase activity
CFN49_RS09470	COG1388	LysM domain
CFN49_RS09470	COG3584	3D domain protein
CFN49_RS09475	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CFN49_RS09480	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CFN49_RS09515	COG0569	domain protein
CFN49_RS09520	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CFN49_RS09525	COG0482	sulfurtransferase activity
CFN49_RS09535	COG1104	cysteine desulfurase activity
CFN49_RS09540	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CFN49_RS09550	COG0494	nUDIX hydrolase
CFN49_RS09555	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
CFN49_RS09565	COG3279	Response regulator of the LytR AlgR family
CFN49_RS09580	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
CFN49_RS09585	COG3599	regulation of cell shape
CFN49_RS09595	COG0762	integral membrane protein
CFN49_RS09600	COG1799	cell septum assembly
CFN49_RS09615	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
CFN49_RS09620	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CFN49_RS09625	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
CFN49_RS09630	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CFN49_RS09635	COG0768	penicillin binding
CFN49_RS09645	COG0275	rRNA processing
CFN49_RS09650	COG2001	Belongs to the MraZ family
CFN49_RS09670	COG1674	ftsk spoiiie
CFN49_RS09675	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
CFN49_RS09685	COG1114	Component of the transport system for branched-chain amino acids
CFN49_RS09700	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
CFN49_RS09705	COG0628	permease
CFN49_RS09715	COG2706	6-phosphogluconolactonase activity
CFN49_RS09720	COG3142	Participates in the control of copper homeostasis
CFN49_RS09725	COG0564	pseudouridine synthase activity
CFN49_RS09730	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CFN49_RS09735	COG2357	RelA SpoT domain protein
CFN49_RS09745	COG1164	Oligoendopeptidase f
CFN49_RS09755	COG4862	establishment of competence for transformation
CFN49_RS09760	COG1393	Belongs to the ArsC family
CFN49_RS09765	COG1234	tRNA 3'-trailer cleavage
CFN49_RS09905	COG1098	S1 RNA binding domain
CFN49_RS09915	COG0586	Pfam SNARE associated Golgi protein
CFN49_RS09925	COG0647	UMP catabolic process
CFN49_RS09930	COG4470	Protein conserved in bacteria
CFN49_RS09935	COG0737	Belongs to the 5'-nucleotidase family
CFN49_RS09950	COG1113	amino acid transport
CFN49_RS09955	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CFN49_RS09960	COG0827	DNA restriction-modification system
CFN49_RS09990	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CFN49_RS10000	COG0217	transcriptional regulatory protein
CFN49_RS10090	COG1705	Flagellar rod assembly protein muramidase FlgJ
CFN49_RS10090	COG1388	LysM domain
CFN49_RS10150	COG1609	Transcriptional regulator
CFN49_RS10155	COG0006	proline dipeptidase activity
CFN49_RS10160	COG0789	Transcriptional regulator
CFN49_RS10175	COG0668	transmembrane transport
CFN49_RS10180	COG1473	amidohydrolase
CFN49_RS10185	COG2171	N-acyltransferase activity
CFN49_RS10190	COG0517	IMP dehydrogenase activity
CFN49_RS10200	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
CFN49_RS10205	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
CFN49_RS10210	COG1719	4-vinyl reductase, 4VR
CFN49_RS10215	COG3118	belongs to the thioredoxin family
CFN49_RS10220	COG1193	negative regulation of DNA recombination
CFN49_RS10230	COG3906	Belongs to the UPF0473 family
CFN49_RS10235	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
CFN49_RS10240	COG4472	Bacterial protein of unknown function (DUF965)
CFN49_RS10245	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CFN49_RS10250	COG0513	Belongs to the DEAD box helicase family
CFN49_RS10255	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
CFN49_RS10260	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CFN49_RS10265	COG1862	Preprotein translocase
CFN49_RS10270	COG0343	queuine tRNA-ribosyltransferase activity
CFN49_RS10275	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
CFN49_RS10280	COG2255	four-way junction helicase activity
CFN49_RS10285	COG0632	four-way junction helicase activity
CFN49_RS10315	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
CFN49_RS10320	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
CFN49_RS10325	COG1692	metallophosphoesterase
CFN49_RS10330	COG1418	mRNA catabolic process
CFN49_RS10335	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
CFN49_RS10340	COG1058	Belongs to the CinA family
CFN49_RS10340	COG1546	Belongs to the CinA family
CFN49_RS10345	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CFN49_RS10350	COG1426	Protein conserved in bacteria
CFN49_RS10355	COG0612	Peptidase, M16
CFN49_RS10360	COG0612	Peptidase, M16
CFN49_RS10365	COG0527	aspartate kinase activity
CFN49_RS10375	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CFN49_RS10380	COG1126	abc transporter atp-binding protein
CFN49_RS10385	COG0765	amino acid transport
CFN49_RS10390	COG2894	cell division
CFN49_RS10395	COG0850	regulation of cytokinetic process
CFN49_RS10405	COG1792	Involved in formation and maintenance of cell shape
CFN49_RS10410	COG1077	Cell shape determining protein MreB Mrl
CFN49_RS10415	COG2003	Belongs to the UPF0758 family
CFN49_RS10420	COG0285	dihydrofolate synthase activity
CFN49_RS10425	COG0525	valine-tRNA ligase activity
CFN49_RS10435	COG2918	glutathione biosynthetic process
CFN49_RS10435	COG1181	Belongs to the D-alanine--D-alanine ligase family
CFN49_RS10440	COG0301	tRNA thio-modification
CFN49_RS10445	COG1104	cysteine desulfurase activity
CFN49_RS10455	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
CFN49_RS10460	COG1956	GAF domain-containing protein
CFN49_RS10465	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
CFN49_RS10470	COG4493	Belongs to the UPF0637 family
CFN49_RS10490	COG0366	Alpha amylase catalytic
CFN49_RS10500	COG3716	PTS system mannose fructose sorbose family IID component
CFN49_RS10505	COG3715	PTS system
CFN49_RS10510	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CFN49_RS10515	COG1609	Transcriptional regulator
CFN49_RS10520	COG2918	glutathione biosynthetic process
CFN49_RS10520	COG0189	ligase activity
CFN49_RS10525	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CFN49_RS10540	COG0589	response to stress
CFN49_RS10560	COG1181	Belongs to the D-alanine--D-alanine ligase family
CFN49_RS10580	COG1464	Belongs to the NlpA lipoprotein family
CFN49_RS10585	COG2011	ABC-type metal ion transport system permease component
CFN49_RS10590	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CFN49_RS10595	COG0509	glycine decarboxylation via glycine cleavage system
CFN49_RS10600	COG0772	Belongs to the SEDS family
CFN49_RS10610	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
CFN49_RS10615	COG1077	Cell shape determining protein MreB Mrl
CFN49_RS10625	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CFN49_RS10630	COG0355	proton-transporting ATP synthase activity, rotational mechanism
CFN49_RS10635	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
CFN49_RS10640	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
CFN49_RS10645	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
CFN49_RS10650	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CFN49_RS10655	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
CFN49_RS10660	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CFN49_RS10665	COG0356	it plays a direct role in the translocation of protons across the membrane
CFN49_RS10670	COG2233	PERMEase
CFN49_RS10680	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
CFN49_RS10685	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
CFN49_RS10690	COG0009	L-threonylcarbamoyladenylate synthase
CFN49_RS10695	COG2890	protein-(glutamine-N5) methyltransferase activity
CFN49_RS10700	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
CFN49_RS10705	COG1435	thymidine kinase activity
CFN49_RS10710	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
CFN49_RS10715	COG3442	glutamine amidotransferase
CFN49_RS10720	COG1482	cell wall glycoprotein biosynthetic process
CFN49_RS10725	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CFN49_RS10735	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CFN49_RS10750	COG1132	(ABC) transporter
CFN49_RS10765	COG0726	polysaccharide deacetylase
CFN49_RS10895	COG2868	ribosomal protein
CFN49_RS10910	COG3728	DNA packaging
CFN49_RS10910	COG5484	DNA packaging
CFN49_RS11045	COG1970	mechanosensitive ion channel activity
CFN49_RS11055	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
CFN49_RS11120	COG4886	Leucine-rich repeat (LRR) protein
CFN49_RS11120	COG4932	domain protein
CFN49_RS11165	COG1132	(ABC) transporter
CFN49_RS11175	COG0577	efflux transmembrane transporter activity
CFN49_RS11175	COG1136	(ABC) transporter
CFN49_RS11185	COG0166	Belongs to the GPI family
CFN49_RS11190	COG4975	Glucose uptake
CFN49_RS11195	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
CFN49_RS11200	COG3850	Histidine kinase
CFN49_RS11200	COG5002	protein histidine kinase activity
CFN49_RS11205	COG0745	RESPONSE REGULATOR receiver
CFN49_RS11210	COG2848	UPF0210 protein
CFN49_RS11215	COG3830	Belongs to the UPF0237 family
CFN49_RS11240	COG0477	Major facilitator Superfamily
CFN49_RS11260	COG0791	NLP P60 protein
CFN49_RS11265	COG1522	sequence-specific DNA binding
CFN49_RS11285	COG0488	(ABC) transporter
CFN49_RS11310	COG2190	(PTS) system
CFN49_RS11310	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CFN49_RS11310	COG1263	PTS System
CFN49_RS11315	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CFN49_RS11320	COG1307	EDD domain protein, DegV family
CFN49_RS11330	COG2873	o-acetylhomoserine
CFN49_RS11335	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
CFN49_RS11350	COG4120	Belongs to the binding-protein-dependent transport system permease family
CFN49_RS11360	COG0446	pyridine nucleotide-disulphide oxidoreductase
CFN49_RS11370	COG2084	Dehydrogenase
CFN49_RS11375	COG0861	Integral membrane protein TerC family
CFN49_RS11380	COG0110	maltose O-acetyltransferase activity
CFN49_RS11385	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CFN49_RS11390	COG0140	phosphoribosyl-ATP diphosphatase activity
CFN49_RS11395	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
CFN49_RS11400	COG0107	imidazoleglycerol-phosphate synthase activity
CFN49_RS11405	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
CFN49_RS11410	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
CFN49_RS11415	COG0131	Imidazoleglycerol-phosphate dehydratase
CFN49_RS11420	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
CFN49_RS11425	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
CFN49_RS11430	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
CFN49_RS11435	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
CFN49_RS11455	COG0789	Transcriptional regulator
CFN49_RS11470	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CFN49_RS11485	COG3548	integral membrane protein
CFN49_RS11505	COG1368	sulfuric ester hydrolase activity
CFN49_RS11510	COG0584	glycerophosphoryl diester phosphodiesterase
CFN49_RS11520	COG0492	ferredoxin-NADP+ reductase activity
CFN49_RS11535	COG2326	polyphosphate kinase activity
CFN49_RS11540	COG0778	Nitroreductase
CFN49_RS11550	COG0328	RNA-DNA hybrid ribonuclease activity
CFN49_RS11560	COG1609	Transcriptional regulator
CFN49_RS11570	COG0673	inositol 2-dehydrogenase activity
CFN49_RS11575	COG0673	inositol 2-dehydrogenase activity
CFN49_RS11580	COG0025	NhaP-type Na H and K H
CFN49_RS11585	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
CFN49_RS11595	COG1335	isochorismatase
CFN49_RS11605	COG1131	(ABC) transporter
CFN49_RS11610	COG1725	Transcriptional regulator
CFN49_RS11650	COG0028	Belongs to the TPP enzyme family
CFN49_RS11660	COG1073	alpha beta
CFN49_RS11665	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CFN49_RS11670	COG0626	cystathionine gamma-synthase activity
CFN49_RS11700	COG0095	Lipoate-protein ligase
CFN49_RS11705	COG1705	Flagellar rod assembly protein muramidase FlgJ
CFN49_RS11715	COG3716	PTS system mannose fructose sorbose family IID component
CFN49_RS11720	COG3715	PTS system
CFN49_RS11725	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CFN49_RS11730	COG2188	Transcriptional regulator
CFN49_RS11735	COG0589	response to stress
CFN49_RS11740	COG0564	pseudouridine synthase activity
CFN49_RS11745	COG1396	sequence-specific DNA binding
CFN49_RS11760	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
CFN49_RS11770	COG2188	Transcriptional regulator
CFN49_RS11775	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CFN49_RS11785	COG1418	mRNA catabolic process
CFN49_RS11815	COG1253	flavin adenine dinucleotide binding
CFN49_RS11820	COG1780	Probably involved in ribonucleotide reductase function
CFN49_RS11825	COG0025	NhaP-type Na H and K H
CFN49_RS11830	COG2814	Major facilitator Superfamily
CFN49_RS11835	COG0789	Transcriptional regulator
CFN49_RS11840	COG0604	alcohol dehydrogenase
CFN49_RS11850	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
CFN49_RS11860	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CFN49_RS11865	COG0436	Aminotransferase
CFN49_RS11870	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CFN49_RS11885	COG0583	DNA-binding transcription factor activity
CFN49_RS11890	COG0702	epimerase
CFN49_RS11900	COG1074	ATP-dependent DNA helicase activity
CFN49_RS11905	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
CFN49_RS11915	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
CFN49_RS11920	COG0284	orotidine-5'-phosphate decarboxylase activity
CFN49_RS11925	COG0167	dihydroorotate dehydrogenase activity
CFN49_RS11930	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
CFN49_RS11935	COG0505	Belongs to the CarA family
CFN49_RS11940	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
CFN49_RS11945	COG0540	Belongs to the ATCase OTCase family
CFN49_RS11950	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
CFN49_RS11955	COG2508	Transcriptional regulator
CFN49_RS11960	COG2233	PERMEase
CFN49_RS11965	COG2252	PERMEase
CFN49_RS11985	COG1215	transferase activity, transferring glycosyl groups
CFN49_RS11995	COG0151	Belongs to the GarS family
CFN49_RS12000	COG0138	bifunctional purine biosynthesis protein purh
CFN49_RS12005	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
CFN49_RS12010	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
CFN49_RS12020	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CFN49_RS12025	COG0047	phosphoribosylformylglycinamidine synthase activity
CFN49_RS12030	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CFN49_RS12035	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
CFN49_RS12040	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
CFN49_RS12050	COG1053	succinate dehydrogenase
CFN49_RS12050	COG0431	NADPH-dependent FMN reductase
CFN49_RS12050	COG3976	FMN-binding domain protein
CFN49_RS12055	COG0431	NADPH-dependent FMN reductase
CFN49_RS12055	COG1053	succinate dehydrogenase
CFN49_RS12055	COG3976	FMN-binding domain protein
CFN49_RS12060	COG0095	Lipoate-protein ligase
CFN49_RS12065	COG2365	Tyrosine phosphatase family
CFN49_RS12085	COG1136	(ABC) transporter
CFN49_RS12100	COG1725	Transcriptional regulator
CFN49_RS12105	COG1131	(ABC) transporter
CFN49_RS12115	COG0589	response to stress
CFN49_RS12125	COG2246	polysaccharide biosynthetic process
CFN49_RS12145	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
CFN49_RS12165	COG0366	Alpha amylase catalytic
CFN49_RS12175	COG0561	phosphatase activity
CFN49_RS12185	COG0110	maltose O-acetyltransferase activity
CFN49_RS12190	COG0494	nUDIX hydrolase
CFN49_RS12220	COG1827	regulation of RNA biosynthetic process
CFN49_RS12225	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
CFN49_RS12230	COG1309	transcriptional regulator
CFN49_RS12240	COG1131	(ABC) transporter
CFN49_RS12245	COG3048	D-serine ammonia-lyase activity
CFN49_RS12250	COG2723	6-phospho-beta-galactosidase activity
CFN49_RS12255	COG2723	6-phospho-beta-galactosidase activity
CFN49_RS12260	COG1447	Phosphotransferase system cellobiose-specific component IIA
CFN49_RS12265	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CFN49_RS12270	COG2188	Transcriptional regulator
CFN49_RS12275	COG1216	Glycosyl transferase, family 2
CFN49_RS12290	COG0561	phosphatase activity
CFN49_RS12295	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CFN49_RS12320	COG0716	FMN binding
CFN49_RS12340	COG0710	3-dehydroquinate dehydratase activity
CFN49_RS12345	COG0531	amino acid
CFN49_RS12360	COG0656	L-ascorbic acid biosynthetic process
CFN49_RS12390	COG4720	Psort location CytoplasmicMembrane, score
CFN49_RS12395	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CFN49_RS12410	COG4990	cell redox homeostasis
CFN49_RS12430	COG1811	Na channel or pump
CFN49_RS12435	COG0789	Transcriptional regulator
CFN49_RS12435	COG4978	Transcriptional regulator
CFN49_RS12450	COG0577	efflux transmembrane transporter activity
CFN49_RS12455	COG1136	(ABC) transporter
CFN49_RS12495	COG2814	Major facilitator Superfamily
CFN49_RS12505	COG2814	Major facilitator Superfamily
CFN49_RS12515	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CFN49_RS12520	COG2855	membrane
CFN49_RS12525	COG0583	DNA-binding transcription factor activity
CFN49_RS12535	COG0438	transferase activity, transferring glycosyl groups
CFN49_RS12550	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CFN49_RS12565	COG4152	abc transporter atp-binding protein
CFN49_RS12575	COG4221	oxidoreductase activity
CFN49_RS12590	COG0789	Transcriptional regulator
CFN49_RS12610	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CFN49_RS12635	COG0456	acetyltransferase
CFN49_RS12660	COG0583	DNA-binding transcription factor activity
CFN49_RS12670	COG1063	alcohol dehydrogenase
CFN49_RS12675	COG1028	Short-chain dehydrogenase reductase Sdr
CFN49_RS12700	COG4975	Glucose uptake
CFN49_RS12710	COG0656	L-ascorbic acid biosynthetic process
CFN49_RS12715	COG0583	DNA-binding transcription factor activity
CFN49_RS12735	COG4221	oxidoreductase activity
CFN49_RS12740	COG0656	L-ascorbic acid biosynthetic process
CFN49_RS12770	COG1396	sequence-specific DNA binding
CFN49_RS12780	COG0589	response to stress
CFN49_RS12785	COG0110	maltose O-acetyltransferase activity
CFN49_RS12790	COG1011	Hydrolase
CFN49_RS12805	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
CFN49_RS12815	COG0667	Aldo Keto reductase
CFN49_RS12820	COG1132	(ABC) transporter
CFN49_RS12825	COG1132	(ABC) transporter
CFN49_RS12830	COG2814	Major facilitator Superfamily
CFN49_RS12845	COG1511	domain protein
CFN49_RS12845	COG1511	domain protein
CFN49_RS12855	COG0640	Transcriptional regulator
CFN49_RS12885	COG0488	(ABC) transporter
CFN49_RS12890	COG0561	phosphatase activity
CFN49_RS12900	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CFN49_RS12915	COG2270	Major facilitator Superfamily
CFN49_RS12955	COG2200	EAL domain
CFN49_RS12965	COG1328	CTP reductase activity
CFN49_RS12975	COG0242	peptide deformylase activity
CFN49_RS12985	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CFN49_RS13000	COG0583	DNA-binding transcription factor activity
CFN49_RS13010	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
CFN49_RS13065	COG0697	spore germination
CFN49_RS13090	COG1940	carbohydrate kinase activity
CFN49_RS13095	COG1132	(ABC) transporter
CFN49_RS13105	COG0778	Nitroreductase
CFN49_RS13110	COG2190	(PTS) system
CFN49_RS13110	COG1263	PTS System
CFN49_RS13110	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CFN49_RS13120	COG4120	Belongs to the binding-protein-dependent transport system permease family
CFN49_RS13155	COG0410	ABC transporter
CFN49_RS13170	COG0559	Belongs to the binding-protein-dependent transport system permease family
CFN49_RS13185	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CFN49_RS13185	COG5549	protein import
CFN49_RS13190	COG2246	polysaccharide biosynthetic process
CFN49_RS13200	COG1914	H( )-stimulated, divalent metal cation uptake system
CFN49_RS13220	COG0640	Transcriptional regulator
CFN49_RS13235	COG1136	(ABC) transporter
CFN49_RS13235	COG0577	efflux transmembrane transporter activity
CFN49_RS13270	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CFN49_RS13275	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CFN49_RS13280	COG2723	6-phospho-beta-galactosidase activity
CFN49_RS13290	COG0789	Transcriptional regulator
CFN49_RS13295	COG0741	lytic transglycosylase activity
CFN49_RS13315	COG0803	Belongs to the bacterial solute-binding protein 9 family
CFN49_RS13340	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CFN49_RS13355	COG4221	oxidoreductase activity
CFN49_RS13385	COG1028	Short-chain dehydrogenase reductase Sdr
CFN49_RS13400	COG1132	(ABC) transporter
CFN49_RS13405	COG1132	(ABC) transporter
CFN49_RS13415	COG1473	amidohydrolase
CFN49_RS13420	COG1028	Short-chain dehydrogenase reductase Sdr
CFN49_RS13435	COG0531	amino acid
CFN49_RS13465	COG2217	Heavy metal translocating P-type atpase
CFN49_RS13525	COG1063	alcohol dehydrogenase
CFN49_RS13565	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CFN49_RS13580	COG1733	regulation of RNA biosynthetic process
CFN49_RS13585	COG2814	Major facilitator Superfamily
CFN49_RS13595	COG0367	asparagine synthase
CFN49_RS13600	COG3279	Response regulator of the LytR AlgR family
CFN49_RS13615	COG1309	transcriptional regulator
CFN49_RS13625	COG1012	belongs to the aldehyde dehydrogenase family
CFN49_RS13640	COG1733	regulation of RNA biosynthetic process
CFN49_RS13645	COG0300	oxidoreductase activity
CFN49_RS13665	COG4989	oxidoreductase activity
CFN49_RS13670	COG0477	Major facilitator Superfamily
CFN49_RS13680	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CFN49_RS13685	COG1120	ATPase activity
CFN49_RS13690	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CFN49_RS13695	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CFN49_RS13700	COG1309	transcriptional regulator
CFN49_RS13710	COG4221	oxidoreductase activity
CFN49_RS13715	COG0110	maltose O-acetyltransferase activity
CFN49_RS13720	COG1028	Short-chain dehydrogenase reductase Sdr
CFN49_RS13760	COG0481	GTPase activity
CFN49_RS13775	COG2816	NAD+ diphosphatase activity
CFN49_RS13785	COG1053	succinate dehydrogenase
CFN49_RS13795	COG0783	Belongs to the Dps family
CFN49_RS13815	COG2723	6-phospho-beta-galactosidase activity
CFN49_RS13820	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CFN49_RS13820	COG1263	PTS System
CFN49_RS13820	COG2190	(PTS) system
CFN49_RS13845	COG3711	transcriptional antiterminator
CFN49_RS13860	COG0693	protein deglycase activity
CFN49_RS13880	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
CFN49_RS13905	COG1376	ErfK ybiS ycfS ynhG family protein
CFN49_RS13925	COG0477	Major facilitator Superfamily
CFN49_RS13960	COG0588	phosphoglycerate mutase activity
CFN49_RS13965	COG0628	permease
CFN49_RS13970	COG1940	carbohydrate kinase activity
CFN49_RS13970	COG1846	Transcriptional regulator
CFN49_RS13980	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CFN49_RS13990	COG2815	serine threonine protein kinase
CFN49_RS13990	COG0515	serine threonine protein kinase
CFN49_RS14030	COG1247	-acetyltransferase
CFN49_RS14035	COG1686	Belongs to the peptidase S11 family
CFN49_RS14055	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CFN49_RS14060	COG0516	GMP reductase activity
CFN49_RS14060	COG0517	IMP dehydrogenase activity
CFN49_RS14070	COG0012	GTP binding
CFN49_RS14075	COG4481	Protein conserved in bacteria
CFN49_RS14080	COG1475	DNA binding
CFN49_RS14085	COG1192	Involved in chromosome partitioning
CFN49_RS14095	COG0357	Ribosomal RNA small subunit methyltransferase G
CFN49_RS14100	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CFN49_RS14115	COG0583	DNA-binding transcription factor activity
CFN49_RS14120	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CFN49_RS14125	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CFN49_RS14130	COG0765	amino acid transport
CFN49_RS14135	COG1126	abc transporter atp-binding protein
CFN49_RS14140	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CFN49_RS14165	COG1263	PTS System
CFN49_RS14165	COG2190	(PTS) system
CFN49_RS14165	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CFN49_RS14170	COG0366	Alpha amylase catalytic
CFN49_RS14175	COG1609	Transcriptional regulator
CFN49_RS14190	COG0390	transport system, permease component
CFN49_RS14195	COG4619	ABC transporter
CFN49_RS14200	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CFN49_RS14215	COG0561	phosphatase activity
CFN49_RS14225	COG0383	alpha-mannosidase activity
CFN49_RS14230	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CFN49_RS14230	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CFN49_RS14230	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CFN49_RS14235	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CFN49_RS14240	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CFN49_RS14240	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CFN49_RS14240	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CFN49_RS14245	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CFN49_RS14245	COG3711	transcriptional antiterminator
CFN49_RS14260	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CFN49_RS14260	COG2190	(PTS) system
CFN49_RS14260	COG1263	PTS System
CFN49_RS14290	COG0735	belongs to the Fur family
CFN49_RS14315	COG1380	Effector of murein hydrolase LrgA
CFN49_RS14325	COG1307	EDD domain protein, DegV family
CFN49_RS14335	COG2738	Putative neutral zinc metallopeptidase
CFN49_RS14340	COG1233	COG1233 Phytoene dehydrogenase and related
CFN49_RS14345	COG1562	ergosterol biosynthetic process
CFN49_RS14355	COG1929	Belongs to the glycerate kinase type-1 family
CFN49_RS14370	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CFN49_RS14375	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
CFN49_RS14380	COG0516	GMP reductase activity
CFN49_RS14385	COG2365	Tyrosine phosphatase family
CFN49_RS14390	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CFN49_RS14400	COG0531	amino acid
CFN49_RS14405	COG3158	transport of potassium into the cell
CFN49_RS14410	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
CFN49_RS14415	COG0628	permease
CFN49_RS14420	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
CFN49_RS14435	COG1272	protein, Hemolysin III
CFN49_RS14440	COG0640	Transcriptional regulator
CFN49_RS14475	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
CFN49_RS14485	COG0302	gtp cyclohydrolase
CFN49_RS14490	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CFN49_RS14510	COG0803	Belongs to the bacterial solute-binding protein 9 family
CFN49_RS14515	COG2814	Major facilitator Superfamily
CFN49_RS14550	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CFN49_RS14555	COG1882	Formate acetyltransferase
CFN49_RS14560	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
CFN49_RS14570	COG2151	metal-sulfur cluster biosynthetic enzyme
CFN49_RS14575	COG4989	oxidoreductase activity
CFN49_RS14610	COG2217	Heavy metal translocating P-type atpase
CFN49_RS14620	COG2315	Protein conserved in bacteria
CFN49_RS14630	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
CFN49_RS14635	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CFN49_RS14645	COG1757	Na H antiporter
CFN49_RS14650	COG1113	amino acid transport
CFN49_RS14660	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
CFN49_RS14675	COG1393	Belongs to the ArsC family
CFN49_RS14680	COG3189	MarR family transcriptional regulator
CFN49_RS14690	COG1194	a g-specific adenine glycosylase
CFN49_RS14705	COG0071	Belongs to the small heat shock protein (HSP20) family
CFN49_RS14725	COG0697	spore germination
CFN49_RS14740	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
CFN49_RS14765	COG0477	Major facilitator Superfamily
CFN49_RS14825	COG0737	Belongs to the 5'-nucleotidase family
CFN49_RS14835	COG0656	L-ascorbic acid biosynthetic process
CFN49_RS14855	COG1968	undecaprenyl-diphosphatase activity
CFN49_RS14860	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
CFN49_RS14895	COG2207	Transcriptional regulator
CFN49_RS14920	COG0076	glutamate decarboxylase activity
CFN49_RS14960	COG1309	transcriptional regulator
CFN49_RS14970	COG2226	methyltransferase
CFN49_RS14990	COG2217	Heavy metal translocating P-type atpase
CFN49_RS14995	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
CFN49_RS15000	COG3118	belongs to the thioredoxin family
CFN49_RS15005	COG1937	Protein conserved in bacteria
CFN49_RS15025	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CFN49_RS15030	COG3590	peptidase
CFN49_RS15055	COG0446	pyridine nucleotide-disulphide oxidoreductase
CFN49_RS15105	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
CFN49_RS15115	COG1114	Component of the transport system for branched-chain amino acids
CFN49_RS15125	COG1874	Beta-galactosidase
CFN49_RS15130	COG1609	Transcriptional regulator
CFN49_RS15140	COG0477	Major facilitator Superfamily
CFN49_RS15160	COG2184	nucleotidyltransferase activity
CFN49_RS15165	COG2944	sequence-specific DNA binding
CFN49_RS15170	COG1609	Transcriptional regulator
CFN49_RS15175	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
CFN49_RS15180	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CFN49_RS15185	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
CFN49_RS15205	COG2211	Major facilitator Superfamily
CFN49_RS15205	COG2190	(PTS) system
CFN49_RS15210	COG2017	converts alpha-aldose to the beta-anomer
CFN49_RS15215	COG1609	Transcriptional regulator
CFN49_RS15220	COG0667	Aldo Keto reductase
CFN49_RS15240	COG0710	3-dehydroquinate dehydratase activity
CFN49_RS15245	COG0738	Major facilitator superfamily
CFN49_RS15250	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CFN49_RS15255	COG0583	DNA-binding transcription factor activity
CFN49_RS15260	COG0738	Major facilitator superfamily
CFN49_RS15275	COG2188	Transcriptional regulator
CFN49_RS15280	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CFN49_RS15285	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
CFN49_RS15290	COG2971	BadF BadG BcrA BcrD
CFN49_RS15300	COG2723	6-phospho-beta-galactosidase activity
CFN49_RS15310	COG3711	transcriptional antiterminator
CFN49_RS15315	COG2723	6-phospho-beta-galactosidase activity
CFN49_RS15320	COG2723	6-phospho-beta-galactosidase activity
CFN49_RS15325	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CFN49_RS15325	COG2190	(PTS) system
CFN49_RS15325	COG1263	PTS System
CFN49_RS15345	COG2211	Major facilitator Superfamily
CFN49_RS15360	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
CFN49_RS15375	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CFN49_RS15380	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CFN49_RS15385	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CFN49_RS15385	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
CFN49_RS15385	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CFN49_RS15390	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CFN49_RS15405	COG3711	transcriptional antiterminator
CFN49_RS15415	COG3775	system Galactitol-specific IIC component
CFN49_RS15420	COG3414	Phosphotransferase system galactitol-specific IIB component
CFN49_RS15430	COG1349	DNA-binding transcription factor activity
CFN49_RS15435	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
CFN49_RS15445	COG0110	maltose O-acetyltransferase activity
CFN49_RS15450	COG2160	L-arabinose isomerase activity
CFN49_RS15470	COG1609	Transcriptional regulator
CFN49_RS15475	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
CFN49_RS15505	COG2261	transglycosylase associated protein
CFN49_RS15515	COG1393	Belongs to the ArsC family
CFN49_RS15535	COG4512	PFAM Accessory gene regulator B
CFN49_RS15550	COG1304	FMN binding
CFN49_RS15555	COG0028	Belongs to the TPP enzyme family
CFN49_RS15560	COG1959	2 iron, 2 sulfur cluster binding
CFN49_RS15565	COG0028	Belongs to the TPP enzyme family
CFN49_RS15580	COG3328	transposase activity
CFN49_RS15590	COG2188	Transcriptional regulator
CFN49_RS15605	COG3732	PTS system glucitol sorbitol-specific
CFN49_RS15610	COG3730	PTS system glucitol sorbitol-specific
CFN49_RS15630	COG4975	Glucose uptake
CFN49_RS15635	COG1869	D-ribose catabolic process
CFN49_RS15645	COG1609	Transcriptional regulator
CFN49_RS15650	COG1012	belongs to the aldehyde dehydrogenase family
CFN49_RS15650	COG1454	alcohol dehydrogenase
CFN49_RS15660	COG1695	Transcriptional regulator
CFN49_RS15665	COG3479	Phenolic acid decarboxylase
CFN49_RS15680	COG1307	EDD domain protein, DegV family
CFN49_RS15720	COG0445	tRNA wobble uridine modification
CFN49_RS15725	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
CFN49_RS15730	COG1847	R3H domain protein
CFN49_RS15740	COG4166	transmembrane transport
CFN49_RS15745	COG0706	membrane insertase activity
CFN49_RS15750	COG0594	ribonuclease P activity
CFN49_RS15755	COG0230	Belongs to the bacterial ribosomal protein bL34 family