locus-tag	class	description
EEJ46_RS00010	COG0561	phosphatase activity
EEJ46_RS00015	COG0488	(ABC) transporter
EEJ46_RS00045	COG0640	Transcriptional regulator
EEJ46_RS00070	COG2814	Major facilitator Superfamily
EEJ46_RS00075	COG1132	(ABC) transporter
EEJ46_RS00080	COG1132	(ABC) transporter
EEJ46_RS00085	COG0667	Aldo Keto reductase
EEJ46_RS00095	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
EEJ46_RS00110	COG1011	Hydrolase
EEJ46_RS00115	COG0110	maltose O-acetyltransferase activity
EEJ46_RS00120	COG0589	response to stress
EEJ46_RS00140	COG0656	L-ascorbic acid biosynthetic process
EEJ46_RS00145	COG4221	oxidoreductase activity
EEJ46_RS00165	COG0583	DNA-binding transcription factor activity
EEJ46_RS00170	COG0656	L-ascorbic acid biosynthetic process
EEJ46_RS00180	COG4975	Glucose uptake
EEJ46_RS00200	COG0656	L-ascorbic acid biosynthetic process
EEJ46_RS00205	COG1028	Short-chain dehydrogenase reductase Sdr
EEJ46_RS00210	COG1063	alcohol dehydrogenase
EEJ46_RS00220	COG0583	DNA-binding transcription factor activity
EEJ46_RS00245	COG0456	acetyltransferase
EEJ46_RS00270	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
EEJ46_RS00295	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
EEJ46_RS00300	COG0789	Transcriptional regulator
EEJ46_RS00315	COG4221	oxidoreductase activity
EEJ46_RS00325	COG4152	abc transporter atp-binding protein
EEJ46_RS00345	COG0438	transferase activity, transferring glycosyl groups
EEJ46_RS00355	COG0583	DNA-binding transcription factor activity
EEJ46_RS00360	COG2855	membrane
EEJ46_RS00365	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EEJ46_RS00375	COG2814	Major facilitator Superfamily
EEJ46_RS00435	COG1136	(ABC) transporter
EEJ46_RS00455	COG4978	Transcriptional regulator
EEJ46_RS00455	COG0789	Transcriptional regulator
EEJ46_RS00460	COG1811	Na channel or pump
EEJ46_RS00480	COG4990	cell redox homeostasis
EEJ46_RS00495	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
EEJ46_RS00500	COG4720	Psort location CytoplasmicMembrane, score
EEJ46_RS00545	COG0531	amino acid
EEJ46_RS00550	COG0710	3-dehydroquinate dehydratase activity
EEJ46_RS00570	COG0716	FMN binding
EEJ46_RS00595	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
EEJ46_RS00600	COG0561	phosphatase activity
EEJ46_RS00615	COG1216	Glycosyl transferase, family 2
EEJ46_RS00620	COG2188	Transcriptional regulator
EEJ46_RS00625	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EEJ46_RS00630	COG1447	Phosphotransferase system cellobiose-specific component IIA
EEJ46_RS00635	COG2723	6-phospho-beta-galactosidase activity
EEJ46_RS00640	COG2723	6-phospho-beta-galactosidase activity
EEJ46_RS00645	COG3048	D-serine ammonia-lyase activity
EEJ46_RS00650	COG1131	(ABC) transporter
EEJ46_RS00660	COG1309	transcriptional regulator
EEJ46_RS00665	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
EEJ46_RS00670	COG1827	regulation of RNA biosynthetic process
EEJ46_RS00705	COG0494	nUDIX hydrolase
EEJ46_RS00710	COG0110	maltose O-acetyltransferase activity
EEJ46_RS00720	COG0561	phosphatase activity
EEJ46_RS00730	COG0366	Alpha amylase catalytic
EEJ46_RS00750	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
EEJ46_RS00780	COG0589	response to stress
EEJ46_RS00795	COG1131	(ABC) transporter
EEJ46_RS00800	COG1725	Transcriptional regulator
EEJ46_RS00815	COG1136	(ABC) transporter
EEJ46_RS00835	COG2365	Tyrosine phosphatase family
EEJ46_RS00840	COG0095	Lipoate-protein ligase
EEJ46_RS00845	COG0431	NADPH-dependent FMN reductase
EEJ46_RS00845	COG1053	succinate dehydrogenase
EEJ46_RS00845	COG3976	FMN-binding domain protein
EEJ46_RS00850	COG0431	NADPH-dependent FMN reductase
EEJ46_RS00850	COG1053	succinate dehydrogenase
EEJ46_RS00850	COG3976	FMN-binding domain protein
EEJ46_RS00860	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
EEJ46_RS00865	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
EEJ46_RS00870	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EEJ46_RS00875	COG0047	phosphoribosylformylglycinamidine synthase activity
EEJ46_RS00880	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EEJ46_RS00890	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
EEJ46_RS00895	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
EEJ46_RS00900	COG0138	bifunctional purine biosynthesis protein purh
EEJ46_RS00905	COG0151	Belongs to the GarS family
EEJ46_RS00915	COG1215	transferase activity, transferring glycosyl groups
EEJ46_RS00935	COG2252	PERMEase
EEJ46_RS00940	COG2233	PERMEase
EEJ46_RS00945	COG2508	Transcriptional regulator
EEJ46_RS00950	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
EEJ46_RS00955	COG0540	Belongs to the ATCase OTCase family
EEJ46_RS00960	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
EEJ46_RS00965	COG0505	Belongs to the CarA family
EEJ46_RS00975	COG0167	dihydroorotate dehydrogenase activity
EEJ46_RS00980	COG0284	orotidine-5'-phosphate decarboxylase activity
EEJ46_RS00985	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
EEJ46_RS01000	COG1074	ATP-dependent DNA helicase activity
EEJ46_RS01010	COG0702	epimerase
EEJ46_RS01015	COG0583	DNA-binding transcription factor activity
EEJ46_RS01035	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EEJ46_RS01040	COG0436	Aminotransferase
EEJ46_RS01045	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EEJ46_RS01055	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
EEJ46_RS01065	COG0604	alcohol dehydrogenase
EEJ46_RS01070	COG0789	Transcriptional regulator
EEJ46_RS01075	COG2814	Major facilitator Superfamily
EEJ46_RS01080	COG0025	NhaP-type Na H and K H
EEJ46_RS01085	COG1780	Probably involved in ribonucleotide reductase function
EEJ46_RS01090	COG1253	flavin adenine dinucleotide binding
EEJ46_RS01120	COG1418	mRNA catabolic process
EEJ46_RS01130	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
EEJ46_RS01135	COG2188	Transcriptional regulator
EEJ46_RS01145	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
EEJ46_RS01160	COG1396	sequence-specific DNA binding
EEJ46_RS01165	COG4640	response to antibiotic
EEJ46_RS01180	COG0564	pseudouridine synthase activity
EEJ46_RS01185	COG0589	response to stress
EEJ46_RS01190	COG1705	Flagellar rod assembly protein muramidase FlgJ
EEJ46_RS01195	COG0095	Lipoate-protein ligase
EEJ46_RS01225	COG0626	cystathionine gamma-synthase activity
EEJ46_RS01230	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EEJ46_RS01235	COG1073	alpha beta
EEJ46_RS01245	COG0028	Belongs to the TPP enzyme family
EEJ46_RS01285	COG1725	Transcriptional regulator
EEJ46_RS01290	COG1131	(ABC) transporter
EEJ46_RS01300	COG1335	isochorismatase
EEJ46_RS01305	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
EEJ46_RS01310	COG0025	NhaP-type Na H and K H
EEJ46_RS01315	COG0673	inositol 2-dehydrogenase activity
EEJ46_RS01320	COG0673	inositol 2-dehydrogenase activity
EEJ46_RS01325	COG1737	Transcriptional regulator
EEJ46_RS01330	COG1609	Transcriptional regulator
EEJ46_RS01355	COG1349	DNA-binding transcription factor activity
EEJ46_RS01370	COG4975	Glucose uptake
EEJ46_RS01375	COG0328	RNA-DNA hybrid ribonuclease activity
EEJ46_RS01385	COG0778	Nitroreductase
EEJ46_RS01390	COG2326	polyphosphate kinase activity
EEJ46_RS01395	COG4932	domain protein
EEJ46_RS01405	COG0492	ferredoxin-NADP+ reductase activity
EEJ46_RS01415	COG0584	glycerophosphoryl diester phosphodiesterase
EEJ46_RS01420	COG1368	sulfuric ester hydrolase activity
EEJ46_RS01440	COG3548	integral membrane protein
EEJ46_RS01455	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
EEJ46_RS01485	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
EEJ46_RS01490	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
EEJ46_RS01495	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
EEJ46_RS01500	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
EEJ46_RS01505	COG0131	Imidazoleglycerol-phosphate dehydratase
EEJ46_RS01510	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
EEJ46_RS01515	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
EEJ46_RS01520	COG0107	imidazoleglycerol-phosphate synthase activity
EEJ46_RS01525	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
EEJ46_RS01530	COG0140	phosphoribosyl-ATP diphosphatase activity
EEJ46_RS01535	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
EEJ46_RS01540	COG0110	maltose O-acetyltransferase activity
EEJ46_RS01550	COG2084	Dehydrogenase
EEJ46_RS01555	COG0446	pyridine nucleotide-disulphide oxidoreductase
EEJ46_RS01565	COG4120	Belongs to the binding-protein-dependent transport system permease family
EEJ46_RS01580	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
EEJ46_RS01585	COG2873	o-acetylhomoserine
EEJ46_RS01595	COG1307	EDD domain protein, DegV family
EEJ46_RS01600	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
EEJ46_RS01605	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EEJ46_RS01605	COG1263	PTS System
EEJ46_RS01605	COG2190	(PTS) system
EEJ46_RS01635	COG0488	(ABC) transporter
EEJ46_RS01655	COG1522	sequence-specific DNA binding
EEJ46_RS01660	COG0791	NLP P60 protein
EEJ46_RS01680	COG0477	Major facilitator Superfamily
EEJ46_RS01705	COG3830	Belongs to the UPF0237 family
EEJ46_RS01710	COG2848	UPF0210 protein
EEJ46_RS01715	COG0745	RESPONSE REGULATOR receiver
EEJ46_RS01720	COG5002	protein histidine kinase activity
EEJ46_RS01720	COG3850	Histidine kinase
EEJ46_RS01725	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
EEJ46_RS01730	COG4975	Glucose uptake
EEJ46_RS01735	COG0166	Belongs to the GPI family
EEJ46_RS01745	COG1136	(ABC) transporter
EEJ46_RS01745	COG0577	efflux transmembrane transporter activity
EEJ46_RS01755	COG1132	(ABC) transporter
EEJ46_RS01800	COG4886	Leucine-rich repeat (LRR) protein
EEJ46_RS01800	COG4932	domain protein
EEJ46_RS01860	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
EEJ46_RS01870	COG1970	mechanosensitive ion channel activity
EEJ46_RS01995	COG2868	ribosomal protein
EEJ46_RS02120	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EEJ46_RS02140	COG0726	polysaccharide deacetylase
EEJ46_RS02155	COG1132	(ABC) transporter
EEJ46_RS02170	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EEJ46_RS02180	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EEJ46_RS02185	COG1482	cell wall glycoprotein biosynthetic process
EEJ46_RS02190	COG3442	glutamine amidotransferase
EEJ46_RS02195	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
EEJ46_RS02200	COG1435	thymidine kinase activity
EEJ46_RS02205	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
EEJ46_RS02210	COG2890	protein-(glutamine-N5) methyltransferase activity
EEJ46_RS02215	COG0009	L-threonylcarbamoyladenylate synthase
EEJ46_RS02220	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
EEJ46_RS02225	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
EEJ46_RS02235	COG2233	PERMEase
EEJ46_RS02240	COG0356	it plays a direct role in the translocation of protons across the membrane
EEJ46_RS02245	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
EEJ46_RS02250	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
EEJ46_RS02255	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
EEJ46_RS02260	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
EEJ46_RS02265	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
EEJ46_RS02270	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
EEJ46_RS02280	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
EEJ46_RS02290	COG1077	Cell shape determining protein MreB Mrl
EEJ46_RS02295	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
EEJ46_RS02305	COG0772	Belongs to the SEDS family
EEJ46_RS02310	COG0509	glycine decarboxylation via glycine cleavage system
EEJ46_RS02315	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
EEJ46_RS02320	COG2011	ABC-type metal ion transport system permease component
EEJ46_RS02325	COG1464	Belongs to the NlpA lipoprotein family
EEJ46_RS02345	COG1181	Belongs to the D-alanine--D-alanine ligase family
EEJ46_RS02370	COG0589	response to stress
EEJ46_RS02385	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
EEJ46_RS02395	COG1609	Transcriptional regulator
EEJ46_RS02400	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EEJ46_RS02405	COG3715	PTS system
EEJ46_RS02420	COG0366	Alpha amylase catalytic
EEJ46_RS02425	COG0640	Transcriptional regulator
EEJ46_RS02440	COG4493	Belongs to the UPF0637 family
EEJ46_RS02445	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
EEJ46_RS02450	COG1956	GAF domain-containing protein
EEJ46_RS02455	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
EEJ46_RS02465	COG1104	cysteine desulfurase activity
EEJ46_RS02470	COG0301	tRNA thio-modification
EEJ46_RS02475	COG1181	Belongs to the D-alanine--D-alanine ligase family
EEJ46_RS02475	COG2918	glutathione biosynthetic process
EEJ46_RS02485	COG0525	valine-tRNA ligase activity
EEJ46_RS02490	COG0285	dihydrofolate synthase activity
EEJ46_RS02495	COG2003	Belongs to the UPF0758 family
EEJ46_RS02500	COG1077	Cell shape determining protein MreB Mrl
EEJ46_RS02505	COG1792	Involved in formation and maintenance of cell shape
EEJ46_RS02515	COG0850	regulation of cytokinetic process
EEJ46_RS02520	COG2894	cell division
EEJ46_RS02525	COG0765	amino acid transport
EEJ46_RS02530	COG1126	abc transporter atp-binding protein
EEJ46_RS02535	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EEJ46_RS02545	COG0527	aspartate kinase activity
EEJ46_RS02550	COG0612	Peptidase, M16
EEJ46_RS02555	COG0612	Peptidase, M16
EEJ46_RS02560	COG1426	Protein conserved in bacteria
EEJ46_RS02565	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
EEJ46_RS02570	COG1546	Belongs to the CinA family
EEJ46_RS02570	COG1058	Belongs to the CinA family
EEJ46_RS02575	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
EEJ46_RS02580	COG1418	mRNA catabolic process
EEJ46_RS02585	COG1692	metallophosphoesterase
EEJ46_RS02590	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
EEJ46_RS02595	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
EEJ46_RS02625	COG0632	four-way junction helicase activity
EEJ46_RS02630	COG2255	four-way junction helicase activity
EEJ46_RS02635	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
EEJ46_RS02640	COG0343	queuine tRNA-ribosyltransferase activity
EEJ46_RS02645	COG1862	Preprotein translocase
EEJ46_RS02650	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EEJ46_RS02655	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
EEJ46_RS02660	COG0513	Belongs to the DEAD box helicase family
EEJ46_RS02665	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
EEJ46_RS02670	COG4472	Bacterial protein of unknown function (DUF965)
EEJ46_RS02675	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
EEJ46_RS02680	COG3906	Belongs to the UPF0473 family
EEJ46_RS02690	COG1193	negative regulation of DNA recombination
EEJ46_RS02695	COG3118	belongs to the thioredoxin family
EEJ46_RS02700	COG1719	4-vinyl reductase, 4VR
EEJ46_RS02705	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
EEJ46_RS02710	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
EEJ46_RS02720	COG0517	IMP dehydrogenase activity
EEJ46_RS02725	COG2171	N-acyltransferase activity
EEJ46_RS02730	COG1473	amidohydrolase
EEJ46_RS02735	COG0668	transmembrane transport
EEJ46_RS02750	COG0789	Transcriptional regulator
EEJ46_RS02755	COG0006	proline dipeptidase activity
EEJ46_RS02760	COG1609	Transcriptional regulator
EEJ46_RS02775	COG0217	transcriptional regulatory protein
EEJ46_RS02785	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
EEJ46_RS02815	COG0827	DNA restriction-modification system
EEJ46_RS02820	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
EEJ46_RS02825	COG1113	amino acid transport
EEJ46_RS02840	COG0737	Belongs to the 5'-nucleotidase family
EEJ46_RS02850	COG0647	UMP catabolic process
EEJ46_RS02860	COG0586	Pfam SNARE associated Golgi protein
EEJ46_RS02870	COG1098	S1 RNA binding domain
EEJ46_RS03010	COG1234	tRNA 3'-trailer cleavage
EEJ46_RS03015	COG1393	Belongs to the ArsC family
EEJ46_RS03020	COG4862	establishment of competence for transformation
EEJ46_RS03040	COG2357	RelA SpoT domain protein
EEJ46_RS03045	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
EEJ46_RS03050	COG0564	pseudouridine synthase activity
EEJ46_RS03055	COG3142	Participates in the control of copper homeostasis
EEJ46_RS03060	COG2706	6-phosphogluconolactonase activity
EEJ46_RS03070	COG0628	permease
EEJ46_RS03075	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
EEJ46_RS03085	COG1114	Component of the transport system for branched-chain amino acids
EEJ46_RS03095	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
EEJ46_RS03100	COG1674	ftsk spoiiie
EEJ46_RS03120	COG2001	Belongs to the MraZ family
EEJ46_RS03125	COG0275	rRNA processing
EEJ46_RS03135	COG0768	penicillin binding
EEJ46_RS03140	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EEJ46_RS03145	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
EEJ46_RS03155	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
EEJ46_RS03170	COG1799	cell septum assembly
EEJ46_RS03175	COG0762	integral membrane protein
EEJ46_RS03185	COG3599	regulation of cell shape
EEJ46_RS03190	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
EEJ46_RS03205	COG3279	Response regulator of the LytR AlgR family
EEJ46_RS03215	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
EEJ46_RS03220	COG0494	nUDIX hydrolase
EEJ46_RS03230	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
EEJ46_RS03235	COG1104	cysteine desulfurase activity
EEJ46_RS03245	COG0482	sulfurtransferase activity
EEJ46_RS03250	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
EEJ46_RS03255	COG0569	domain protein
EEJ46_RS03285	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
EEJ46_RS03290	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
EEJ46_RS03295	COG1388	LysM domain
EEJ46_RS03295	COG3584	3D domain protein
EEJ46_RS03305	COG1597	lipid kinase activity
EEJ46_RS03310	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
EEJ46_RS03315	COG5503	Protein of unknown function (DUF1447)
EEJ46_RS03325	COG0242	peptide deformylase activity
EEJ46_RS03350	COG0039	L-malate dehydrogenase activity
EEJ46_RS03355	COG4476	Belongs to the UPF0223 family
EEJ46_RS03360	COG0483	inositol monophosphate 1-phosphatase activity
EEJ46_RS03365	COG1217	gtp-binding protein TYPA
EEJ46_RS03400	COG0772	Belongs to the SEDS family
EEJ46_RS03405	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
EEJ46_RS03410	COG4471	UPF0298 protein
EEJ46_RS03415	COG0742	ribosomal rna small subunit methyltransferase
EEJ46_RS03420	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
EEJ46_RS03425	COG3480	Lon protease (S16) C-terminal proteolytic domain
EEJ46_RS03430	COG1555	photosystem II stabilization
EEJ46_RS03430	COG1596	polysaccharide export
EEJ46_RS03435	COG2131	deaminase
EEJ46_RS03440	COG2333	competence protein COMEC
EEJ46_RS03440	COG0658	competence protein
EEJ46_RS03445	COG1466	dna polymerase III delta subunit
EEJ46_RS03450	COG0268	Binds directly to 16S ribosomal RNA
EEJ46_RS03455	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
EEJ46_RS03480	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
EEJ46_RS03485	COG0544	peptidyl-prolyl cis-trans isomerase activity
EEJ46_RS03490	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
EEJ46_RS03495	COG0218	Necessary for normal cell division and for the maintenance of normal septation
EEJ46_RS03515	COG0765	amino acid transport
EEJ46_RS03520	COG1126	abc transporter atp-binding protein
EEJ46_RS03525	COG0322	excinuclease ABC activity
EEJ46_RS03535	COG0489	protein tyrosine kinase activity
EEJ46_RS03545	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EEJ46_RS03550	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
EEJ46_RS03555	COG0297	glycogen (starch) synthase activity
EEJ46_RS03580	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
EEJ46_RS03585	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EEJ46_RS03585	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EEJ46_RS03585	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EEJ46_RS03590	COG1105	Belongs to the carbohydrate kinase PfkB family
EEJ46_RS03595	COG1349	DNA-binding transcription factor activity
EEJ46_RS03600	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
EEJ46_RS03610	COG1234	tRNA 3'-trailer cleavage
EEJ46_RS03615	COG0300	oxidoreductase activity
EEJ46_RS03620	COG5416	Lipopolysaccharide assembly protein A domain
EEJ46_RS03625	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
EEJ46_RS03625	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
EEJ46_RS03630	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
EEJ46_RS03645	COG0393	Putative heavy-metal-binding
EEJ46_RS03665	COG0772	Belongs to the SEDS family
EEJ46_RS03675	COG1116	anion transmembrane transporter activity
EEJ46_RS03680	COG1316	TRANSCRIPTIONal
EEJ46_RS03690	COG0463	Glycosyl transferase, family 2
EEJ46_RS03705	COG3425	synthase
EEJ46_RS03720	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
EEJ46_RS03725	COG4224	UPF0291 protein
EEJ46_RS03730	COG3763	UPF0154 protein
EEJ46_RS03735	COG0204	Acyl-transferase
EEJ46_RS03740	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
EEJ46_RS03745	COG2827	Endonuclease containing a URI domain
EEJ46_RS03750	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EEJ46_RS03760	COG0052	Belongs to the universal ribosomal protein uS2 family
EEJ46_RS03765	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
EEJ46_RS03770	COG0528	UMP kinase activity
EEJ46_RS03775	COG0233	cytoplasmic translational termination
EEJ46_RS03780	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
EEJ46_RS03785	COG4589	Belongs to the CDS family
EEJ46_RS03795	COG0442	prolyl-tRNA aminoacylation
EEJ46_RS03805	COG0779	Required for maturation of 30S ribosomal subunits
EEJ46_RS03810	COG0195	Participates in both transcription termination and antitermination
EEJ46_RS03815	COG2740	Nucleic-acid-binding protein implicated in transcription termination
EEJ46_RS03825	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
EEJ46_RS03830	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
EEJ46_RS03835	COG0738	Major facilitator superfamily
EEJ46_RS03840	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
EEJ46_RS03850	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
EEJ46_RS03855	COG0287	Prephenate dehydrogenase
EEJ46_RS03860	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
EEJ46_RS03865	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
EEJ46_RS03870	COG0196	riboflavin kinase activity
EEJ46_RS03875	COG3527	Alpha-acetolactate decarboxylase
EEJ46_RS03880	COG1420	regulation of RNA biosynthetic process
EEJ46_RS03885	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
EEJ46_RS03890	COG0443	Heat shock 70 kDa protein
EEJ46_RS03895	COG0484	heat shock protein binding
EEJ46_RS03900	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EEJ46_RS03910	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EEJ46_RS03915	COG1696	Membrane protein involved in D-alanine export
EEJ46_RS03920	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EEJ46_RS03925	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
EEJ46_RS03930	COG0481	GTPase activity
EEJ46_RS03935	COG0582	viral genome integration into host DNA
EEJ46_RS03960	COG2094	Belongs to the DNA glycosylase MPG family
EEJ46_RS03965	COG2264	protein methyltransferase activity
EEJ46_RS03970	COG1385	rRNA (uridine-N3-)-methyltransferase activity
EEJ46_RS03980	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EEJ46_RS03985	COG1490	D-aminoacyl-tRNA deacylase activity
EEJ46_RS03990	COG0546	phosphoglycolate phosphatase activity
EEJ46_RS03995	COG3001	Fructosamine kinase
EEJ46_RS04000	COG4991	sh3 domain protein
EEJ46_RS04000	COG3103	Sh3 type 3 domain protein
EEJ46_RS04000	COG0860	N-Acetylmuramoyl-L-alanine amidase
EEJ46_RS04005	COG0124	histidyl-tRNA synthetase
EEJ46_RS04010	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
EEJ46_RS04020	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EEJ46_RS04030	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
EEJ46_RS04040	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
EEJ46_RS04045	COG0828	Belongs to the bacterial ribosomal protein bS21 family
EEJ46_RS04050	COG1610	YqeY-like protein
EEJ46_RS04055	COG1702	phosphate starvation-inducible protein PhoH
EEJ46_RS04060	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
EEJ46_RS04070	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
EEJ46_RS04075	COG1381	Involved in DNA repair and RecF pathway recombination
EEJ46_RS04080	COG0752	glycyl-tRNA synthetase alpha subunit
EEJ46_RS04085	COG0751	glycine-tRNA ligase activity
EEJ46_RS04090	COG0358	DNA primase activity
EEJ46_RS04095	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EEJ46_RS04105	COG1725	Transcriptional regulator
EEJ46_RS04110	COG1131	(ABC) transporter
EEJ46_RS04130	COG1131	(ABC) transporter
EEJ46_RS04165	COG0519	Catalyzes the synthesis of GMP from XMP
EEJ46_RS04175	COG1131	(ABC) transporter
EEJ46_RS04185	COG4585	Histidine kinase
EEJ46_RS04190	COG2197	response regulator
EEJ46_RS04195	COG0446	pyridine nucleotide-disulphide oxidoreductase
EEJ46_RS04205	COG0604	alcohol dehydrogenase
EEJ46_RS04210	COG0583	DNA-binding transcription factor activity
EEJ46_RS04240	COG0546	phosphoglycolate phosphatase activity
EEJ46_RS04260	COG1393	Belongs to the ArsC family
EEJ46_RS04270	COG1349	DNA-binding transcription factor activity
EEJ46_RS04275	COG0446	pyridine nucleotide-disulphide oxidoreductase
EEJ46_RS04290	COG0477	Major facilitator Superfamily
EEJ46_RS04295	COG0148	phosphopyruvate hydratase activity
EEJ46_RS04300	COG2217	Heavy metal translocating P-type atpase
EEJ46_RS04330	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
EEJ46_RS04330	COG0574	Belongs to the PEP-utilizing enzyme family
EEJ46_RS04355	COG2384	SAM-dependent methyltransferase
EEJ46_RS04360	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
EEJ46_RS04370	COG0542	response to heat
EEJ46_RS04380	COG0587	DNA-directed DNA polymerase activity
EEJ46_RS04385	COG0205	6-phosphofructokinase activity
EEJ46_RS04410	COG2996	Protein conserved in bacteria
EEJ46_RS04415	COG4974	Belongs to the 'phage' integrase family
EEJ46_RS04425	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
EEJ46_RS04430	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
EEJ46_RS04435	COG1187	pseudouridine synthase activity
EEJ46_RS04440	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
EEJ46_RS04450	COG0514	ATP-dependent DNA helicase (RecQ)
EEJ46_RS04460	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
EEJ46_RS04465	COG0539	negative regulation of cytoplasmic translation
EEJ46_RS04470	COG1160	GTP binding
EEJ46_RS04485	COG0457	Tetratricopeptide repeat
EEJ46_RS04490	COG0561	phosphatase activity
EEJ46_RS04495	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
EEJ46_RS04500	COG0617	tRNA 3'-terminal CCA addition
EEJ46_RS04510	COG0488	(ABC) transporter
EEJ46_RS04515	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
EEJ46_RS04520	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
EEJ46_RS04525	COG1307	EDD domain protein, DegV family
EEJ46_RS04530	COG2755	lipolytic protein G-D-S-L family
EEJ46_RS04535	COG4698	Protein conserved in bacteria
EEJ46_RS04540	COG4479	Belongs to the UPF0346 family
EEJ46_RS04545	COG0793	Belongs to the peptidase S41A family
EEJ46_RS04545	COG3409	Peptidoglycan-binding domain 1 protein
EEJ46_RS04550	COG2814	Major facilitator Superfamily
EEJ46_RS04570	COG0583	DNA-binding transcription factor activity
EEJ46_RS04575	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
EEJ46_RS04585	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
EEJ46_RS04590	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
EEJ46_RS04595	COG0758	DNA mediated transformation
EEJ46_RS04600	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EEJ46_RS04605	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
EEJ46_RS04610	COG4974	Belongs to the 'phage' integrase family
EEJ46_RS04615	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
EEJ46_RS04620	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
EEJ46_RS04630	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
EEJ46_RS04635	COG0187	DNA topoisomerase II activity
EEJ46_RS04645	COG0583	DNA-binding transcription factor activity
EEJ46_RS04650	COG1227	inorganic diphosphatase activity
EEJ46_RS04655	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EEJ46_RS04690	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EEJ46_RS04695	COG1846	Transcriptional regulator
EEJ46_RS04720	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
EEJ46_RS04745	COG1113	amino acid transport
EEJ46_RS04805	COG1307	EDD domain protein, DegV family
EEJ46_RS04815	COG1293	RNA-binding protein homologous to eukaryotic snRNP
EEJ46_RS04820	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
EEJ46_RS04825	COG1131	(ABC) transporter
EEJ46_RS04850	COG5646	InterPro IPR014922
EEJ46_RS04865	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
EEJ46_RS04870	COG0505	Belongs to the CarA family
EEJ46_RS04875	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
EEJ46_RS04880	COG0564	pseudouridine synthase activity
EEJ46_RS04885	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
EEJ46_RS04890	COG2759	Belongs to the formate--tetrahydrofolate ligase family
EEJ46_RS04905	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EEJ46_RS04930	COG1619	proteins homologs of microcin C7 resistance protein MccF
EEJ46_RS04950	COG1216	Glycosyl transferase, family 2
EEJ46_RS04960	COG1073	alpha beta
EEJ46_RS04965	COG0116	Belongs to the methyltransferase superfamily
EEJ46_RS04975	COG3599	regulation of cell shape
EEJ46_RS04980	COG4474	Belongs to the UPF0398 family
EEJ46_RS04985	COG3331	DNA recombination
EEJ46_RS05000	COG1840	ABC-type Fe3 transport system, periplasmic component
EEJ46_RS05005	COG1177	transmembrane transport
EEJ46_RS05015	COG1464	Belongs to the NlpA lipoprotein family
EEJ46_RS05020	COG2011	ABC-type metal ion transport system permease component
EEJ46_RS05025	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
EEJ46_RS05040	COG0017	Asparaginyl-tRNA synthetase
EEJ46_RS05055	COG1199	ATP-dependent helicase activity
EEJ46_RS05055	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
EEJ46_RS05080	COG1304	FMN binding
EEJ46_RS05085	COG2017	converts alpha-aldose to the beta-anomer
EEJ46_RS05110	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
EEJ46_RS05110	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
EEJ46_RS05115	COG0561	phosphatase activity
EEJ46_RS05120	COG0531	amino acid
EEJ46_RS05160	COG1942	4-Oxalocrotonate Tautomerase
EEJ46_RS05175	COG3237	CsbD-like
EEJ46_RS05180	COG2261	transglycosylase associated protein
EEJ46_RS05195	COG1597	lipid kinase activity
EEJ46_RS05200	COG3152	Membrane
EEJ46_RS05210	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
EEJ46_RS05225	COG3397	chitin binding
EEJ46_RS05230	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
EEJ46_RS05250	COG0477	Major facilitator Superfamily
EEJ46_RS05260	COG1162	GTPase activity
EEJ46_RS05265	COG1607	acyl-coa hydrolase
EEJ46_RS05270	COG0583	DNA-binding transcription factor activity
EEJ46_RS05275	COG1811	Na channel or pump
EEJ46_RS05285	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
EEJ46_RS05300	COG0439	Biotin carboxylase
EEJ46_RS05315	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
EEJ46_RS05320	COG1028	Short-chain dehydrogenase reductase Sdr
EEJ46_RS05325	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
EEJ46_RS05330	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EEJ46_RS05335	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EEJ46_RS05340	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
EEJ46_RS05350	COG0300	oxidoreductase activity
EEJ46_RS05360	COG1063	alcohol dehydrogenase
EEJ46_RS05380	COG0159	tryptophan synthase activity
EEJ46_RS05385	COG0133	tryptophan synthase activity
EEJ46_RS05390	COG0135	phosphoribosylanthranilate isomerase activity
EEJ46_RS05395	COG0134	indole-3-glycerol-phosphate synthase activity
EEJ46_RS05400	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
EEJ46_RS05405	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
EEJ46_RS05405	COG0512	Glutamine amidotransferase of anthranilate synthase
EEJ46_RS05440	COG0335	large ribosomal subunit rRNA binding
EEJ46_RS05445	COG0336	Belongs to the RNA methyltransferase TrmD family
EEJ46_RS05450	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
EEJ46_RS05455	COG1837	Belongs to the UPF0109 family
EEJ46_RS05460	COG0228	four-way junction DNA binding
EEJ46_RS05465	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
EEJ46_RS05470	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
EEJ46_RS05475	COG0552	protein localization to endoplasmic reticulum
EEJ46_RS05480	COG1196	nuclear chromosome segregation
EEJ46_RS05485	COG0571	ribonuclease III activity
EEJ46_RS05490	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EEJ46_RS05495	COG0416	fatty acid biosynthetic process
EEJ46_RS05500	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
EEJ46_RS05505	COG1461	Dihydroxyacetone kinase
EEJ46_RS05510	COG1302	Protein conserved in bacteria
EEJ46_RS05515	COG0227	Belongs to the bacterial ribosomal protein bL28 family
EEJ46_RS05525	COG1564	THIamine pyrophosphokinase
EEJ46_RS05530	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
EEJ46_RS05535	COG1162	GTPase activity
EEJ46_RS05540	COG2815	serine threonine protein kinase
EEJ46_RS05540	COG0515	serine threonine protein kinase
EEJ46_RS05545	COG0631	protein serine/threonine phosphatase activity
EEJ46_RS05550	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
EEJ46_RS05550	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EEJ46_RS05555	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
EEJ46_RS05560	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
EEJ46_RS05565	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
EEJ46_RS05570	COG1758	RNA polymerase activity
EEJ46_RS05575	COG0194	GDP metabolic process
EEJ46_RS05590	COG1732	Glycine betaine
EEJ46_RS05605	COG0497	DNA recombination
EEJ46_RS05610	COG1438	arginine binding
EEJ46_RS05615	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
EEJ46_RS05620	COG0142	geranyltranstransferase activity
EEJ46_RS05625	COG1722	exodeoxyribonuclease VII activity
EEJ46_RS05630	COG1570	exodeoxyribonuclease VII activity
EEJ46_RS05635	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
EEJ46_RS05640	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EEJ46_RS05645	COG1302	Protein conserved in bacteria
EEJ46_RS05650	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
EEJ46_RS05655	COG0006	proline dipeptidase activity
EEJ46_RS05660	COG0211	Belongs to the bacterial ribosomal protein bL27 family
EEJ46_RS05670	COG0261	This protein binds to 23S rRNA in the presence of protein L20
EEJ46_RS05720	COG0789	Transcriptional regulator
EEJ46_RS05725	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
EEJ46_RS05730	COG0584	glycerophosphoryl diester phosphodiesterase
EEJ46_RS05750	COG1940	carbohydrate kinase activity
EEJ46_RS05760	COG0705	Rhomboid family
EEJ46_RS05760	COG0457	Tetratricopeptide repeat
EEJ46_RS05765	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
EEJ46_RS05770	COG0267	Belongs to the bacterial ribosomal protein bL33 family
EEJ46_RS05775	COG0768	penicillin binding
EEJ46_RS05795	COG1511	domain protein
EEJ46_RS05810	COG4841	protein insertion into membrane
EEJ46_RS05835	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
EEJ46_RS05840	COG0572	uridine kinase
EEJ46_RS05845	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
EEJ46_RS05850	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EEJ46_RS05850	COG0072	phenylalanine-tRNA ligase activity
EEJ46_RS05855	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
EEJ46_RS05860	COG1733	regulation of RNA biosynthetic process
EEJ46_RS05870	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EEJ46_RS05875	COG1254	Belongs to the acylphosphatase family
EEJ46_RS05880	COG0706	membrane insertase activity
EEJ46_RS05895	COG0419	ATPase involved in DNA repair
EEJ46_RS05905	COG5002	protein histidine kinase activity
EEJ46_RS05910	COG0745	RESPONSE REGULATOR receiver
EEJ46_RS05915	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
EEJ46_RS05920	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
EEJ46_RS05935	COG0333	Belongs to the bacterial ribosomal protein bL32 family
EEJ46_RS05945	COG1323	Belongs to the UPF0348 family
EEJ46_RS05950	COG2226	methyltransferase
EEJ46_RS05955	COG0799	negative regulation of ribosome biogenesis
EEJ46_RS05960	COG1713	HD superfamily hydrolase involved in NAD metabolism
EEJ46_RS05965	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
EEJ46_RS05970	COG1534	Rna-binding protein
EEJ46_RS05975	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
EEJ46_RS05990	COG1215	transferase activity, transferring glycosyl groups
EEJ46_RS06000	COG1733	regulation of RNA biosynthetic process
EEJ46_RS06005	COG0604	alcohol dehydrogenase
EEJ46_RS06010	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
EEJ46_RS06020	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
EEJ46_RS06025	COG0291	Belongs to the bacterial ribosomal protein bL35 family
EEJ46_RS06030	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
EEJ46_RS06035	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
EEJ46_RS06040	COG1484	DNA-dependent DNA replication
EEJ46_RS06045	COG3611	Membrane attachment protein
EEJ46_RS06050	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
EEJ46_RS06055	COG0237	dephospho-CoA kinase activity
EEJ46_RS06060	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
EEJ46_RS06065	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EEJ46_RS06065	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EEJ46_RS06075	COG3655	Transcriptional regulator
EEJ46_RS06095	COG2181	nitrate reductase activity
EEJ46_RS06105	COG1140	nitrate reductase beta subunit
EEJ46_RS06110	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
EEJ46_RS06115	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
EEJ46_RS06125	COG0303	'Molybdopterin
EEJ46_RS06130	COG1763	Mo-molybdopterin cofactor biosynthetic process
EEJ46_RS06135	COG0315	cyclic pyranopterin monophosphate synthase activity
EEJ46_RS06160	COG2197	response regulator
EEJ46_RS06185	COG2151	metal-sulfur cluster biosynthetic enzyme
EEJ46_RS06190	COG2223	nitrite transmembrane transporter activity
EEJ46_RS06195	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
EEJ46_RS06210	COG0716	FMN binding
EEJ46_RS06215	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EEJ46_RS06220	COG1120	ATPase activity
EEJ46_RS06235	COG0719	Fe-S assembly protein
EEJ46_RS06245	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
EEJ46_RS06250	COG0719	Fe-S assembly protein
EEJ46_RS06275	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
EEJ46_RS06280	COG1674	ftsk spoiiie
EEJ46_RS06285	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EEJ46_RS06295	COG0220	tRNA (guanine-N7-)-methyltransferase activity
EEJ46_RS06300	COG0510	thiamine kinase activity
EEJ46_RS06305	COG4473	ABC transporter
EEJ46_RS06310	COG1131	(ABC) transporter
EEJ46_RS06315	COG0537	adenosine 5'-monophosphoramidase activity
EEJ46_RS06325	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EEJ46_RS06365	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EEJ46_RS06380	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
EEJ46_RS06385	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
EEJ46_RS06385	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
EEJ46_RS06390	COG0307	riboflavin synthase, alpha
EEJ46_RS06395	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EEJ46_RS06395	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EEJ46_RS06415	COG0463	Glycosyl transferase, family 2
EEJ46_RS06420	COG0586	Pfam SNARE associated Golgi protein
EEJ46_RS06425	COG0463	Glycosyl transferase, family 2
EEJ46_RS06435	COG0745	RESPONSE REGULATOR receiver
EEJ46_RS06440	COG3850	Histidine kinase
EEJ46_RS06440	COG5002	protein histidine kinase activity
EEJ46_RS06460	COG3976	FMN-binding domain protein
EEJ46_RS06460	COG0431	NADPH-dependent FMN reductase
EEJ46_RS06460	COG1053	succinate dehydrogenase
EEJ46_RS06470	COG0583	DNA-binding transcription factor activity
EEJ46_RS06485	COG3481	metal-dependent phosphohydrolase, HD sub domain
EEJ46_RS06490	COG4717	serine-type aminopeptidase activity
EEJ46_RS06495	COG0420	3'-5' exonuclease activity
EEJ46_RS06500	COG3679	Belongs to the UPF0342 family
EEJ46_RS06505	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EEJ46_RS06515	COG1438	arginine binding
EEJ46_RS06520	COG0436	Aminotransferase
EEJ46_RS06535	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EEJ46_RS06540	COG1376	ErfK ybiS ycfS ynhG family protein
EEJ46_RS06565	COG0018	arginyl-trna synthetase
EEJ46_RS06590	COG0534	Mate efflux family protein
EEJ46_RS06605	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
EEJ46_RS06610	COG0529	Catalyzes the synthesis of activated sulfate
EEJ46_RS06615	COG2046	Belongs to the sulfate adenylyltransferase family
EEJ46_RS06625	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
EEJ46_RS06630	COG0646	methionine synthase
EEJ46_RS06630	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
EEJ46_RS06710	COG3953	SLT domain
EEJ46_RS06710	COG5280	Phage tail tape measure protein TP901
EEJ46_RS06885	COG3646	Phage regulatory protein
EEJ46_RS06895	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
EEJ46_RS06945	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
EEJ46_RS06960	COG1846	Transcriptional regulator
EEJ46_RS06980	COG3279	Response regulator of the LytR AlgR family
EEJ46_RS07005	COG0697	spore germination
EEJ46_RS07015	COG0789	Transcriptional regulator
EEJ46_RS07020	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EEJ46_RS07050	COG1511	domain protein
EEJ46_RS07050	COG1511	domain protein
EEJ46_RS07055	COG1970	mechanosensitive ion channel activity
EEJ46_RS07060	COG1428	Deoxynucleoside kinase
EEJ46_RS07065	COG0584	glycerophosphoryl diester phosphodiesterase
EEJ46_RS07075	COG0395	ABC-type sugar transport system, permease component
EEJ46_RS07080	COG1175	transmembrane transport
EEJ46_RS07085	COG3842	ATPase activity
EEJ46_RS07095	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EEJ46_RS07100	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
EEJ46_RS07105	COG1187	pseudouridine synthase activity
EEJ46_RS07110	COG2244	polysaccharide biosynthetic process
EEJ46_RS07115	COG0495	leucyl-tRNA aminoacylation
EEJ46_RS07125	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
EEJ46_RS07135	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EEJ46_RS07150	COG2195	Cleaves the N-terminal amino acid of tripeptides
EEJ46_RS07155	COG0477	Major facilitator Superfamily
EEJ46_RS07160	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
EEJ46_RS07170	COG0438	transferase activity, transferring glycosyl groups
EEJ46_RS07175	COG2040	homocysteine
EEJ46_RS07180	COG0833	amino acid
EEJ46_RS07185	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
EEJ46_RS07200	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
EEJ46_RS07220	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
EEJ46_RS07315	COG1368	sulfuric ester hydrolase activity
EEJ46_RS07320	COG4703	Protein of unknown function (DUF1797)
EEJ46_RS07325	COG0436	Aminotransferase
EEJ46_RS07330	COG1686	Belongs to the peptidase S11 family
EEJ46_RS07340	COG0438	transferase activity, transferring glycosyl groups
EEJ46_RS07345	COG0438	transferase activity, transferring glycosyl groups
EEJ46_RS07365	COG0542	response to heat
EEJ46_RS07370	COG0582	viral genome integration into host DNA
EEJ46_RS07380	COG4608	Belongs to the ABC transporter superfamily
EEJ46_RS07385	COG0444	Belongs to the ABC transporter superfamily
EEJ46_RS07390	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EEJ46_RS07395	COG0601	transmembrane transport
EEJ46_RS07400	COG4166	transmembrane transport
EEJ46_RS07435	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
EEJ46_RS07440	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EEJ46_RS07445	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
EEJ46_RS07450	COG1070	Carbohydrate kinase
EEJ46_RS07455	COG2610	gluconate transmembrane transporter activity
EEJ46_RS07460	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
EEJ46_RS07465	COG0628	permease
EEJ46_RS07490	COG3557	Belongs to the UPF0374 family
EEJ46_RS07495	COG2137	regulation of response to DNA damage stimulus
EEJ46_RS07530	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
EEJ46_RS07550	COG2207	Transcriptional regulator
EEJ46_RS07550	COG1609	Transcriptional regulator
EEJ46_RS07585	COG0562	UDP-galactopyranose mutase
EEJ46_RS07625	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
EEJ46_RS07625	COG1215	transferase activity, transferring glycosyl groups
EEJ46_RS07635	COG1216	Glycosyl transferase, family 2
EEJ46_RS07640	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
EEJ46_RS07650	COG4464	protein tyrosine phosphatase activity
EEJ46_RS07655	COG0489	protein tyrosine kinase activity
EEJ46_RS07665	COG0582	viral genome integration into host DNA
EEJ46_RS07675	COG1091	dTDP-4-dehydrorhamnose reductase activity
EEJ46_RS07680	COG1088	dTDP-glucose 4,6-dehydratase activity
EEJ46_RS07690	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
EEJ46_RS07720	COG0110	maltose O-acetyltransferase activity
EEJ46_RS07725	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
EEJ46_RS07725	COG1215	transferase activity, transferring glycosyl groups
EEJ46_RS07755	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
EEJ46_RS07765	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
EEJ46_RS07775	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
EEJ46_RS07800	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EEJ46_RS07815	COG0513	Belongs to the DEAD box helicase family
EEJ46_RS07820	COG0673	inositol 2-dehydrogenase activity
EEJ46_RS07825	COG1278	Cold shock
EEJ46_RS07840	COG1737	Transcriptional regulator
EEJ46_RS07850	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EEJ46_RS07865	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
EEJ46_RS07870	COG1597	lipid kinase activity
EEJ46_RS07875	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
EEJ46_RS07880	COG0154	amidase activity
EEJ46_RS07885	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
EEJ46_RS07890	COG4851	CamS sex pheromone cAM373 precursor
EEJ46_RS07895	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
EEJ46_RS07910	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
EEJ46_RS07915	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
EEJ46_RS07920	COG1705	Flagellar rod assembly protein muramidase FlgJ
EEJ46_RS07935	COG0142	geranyltranstransferase activity
EEJ46_RS07950	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
EEJ46_RS07955	COG4988	ABC transporter
EEJ46_RS07960	COG1294	oxidase, subunit
EEJ46_RS07965	COG1271	oxidase subunit
EEJ46_RS07980	COG4684	Psort location CytoplasmicMembrane, score
EEJ46_RS07985	COG0531	amino acid
EEJ46_RS07995	COG0281	malic enzyme
EEJ46_RS08000	COG0583	DNA-binding transcription factor activity
EEJ46_RS08005	COG0583	DNA-binding transcription factor activity
EEJ46_RS08015	COG1053	succinate dehydrogenase
EEJ46_RS08020	COG0114	fumarate hydratase activity
EEJ46_RS08050	COG3052	prosthetic group binding
EEJ46_RS08070	COG0471	metal ion transport
EEJ46_RS08075	COG0039	L-malate dehydrogenase activity
EEJ46_RS08085	COG0803	Belongs to the bacterial solute-binding protein 9 family
EEJ46_RS08090	COG1108	ABC-type Mn2 Zn2 transport systems permease components
EEJ46_RS08095	COG1121	(ABC) transporter
EEJ46_RS08100	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
EEJ46_RS08105	COG4977	sequence-specific DNA binding
EEJ46_RS08105	COG1917	Cupin 2, conserved barrel domain protein
EEJ46_RS08115	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
EEJ46_RS08120	COG2151	metal-sulfur cluster biosynthetic enzyme
EEJ46_RS08125	COG0471	metal ion transport
EEJ46_RS08130	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
EEJ46_RS08135	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
EEJ46_RS08140	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
EEJ46_RS08145	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
EEJ46_RS08165	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
EEJ46_RS08170	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
EEJ46_RS08175	COG0101	tRNA pseudouridine synthase activity
EEJ46_RS08185	COG1122	ATPase activity
EEJ46_RS08190	COG1122	ATPase activity
EEJ46_RS08200	COG4939	FMN-binding domain protein
EEJ46_RS08225	COG0203	ribosomal protein L17
EEJ46_RS08230	COG0202	RNA polymerase activity
EEJ46_RS08235	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
EEJ46_RS08240	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
EEJ46_RS08245	COG0257	Belongs to the bacterial ribosomal protein bL36 family
EEJ46_RS08250	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
EEJ46_RS08255	COG0563	adenylate kinase activity
EEJ46_RS08265	COG0200	Binds to the 23S rRNA
EEJ46_RS08270	COG1841	ribosomal large subunit assembly
EEJ46_RS08275	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
EEJ46_RS08280	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
EEJ46_RS08285	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
EEJ46_RS08290	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
EEJ46_RS08295	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
EEJ46_RS08300	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
EEJ46_RS08305	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
EEJ46_RS08310	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
EEJ46_RS08315	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
EEJ46_RS08320	COG0255	Belongs to the universal ribosomal protein uL29 family
EEJ46_RS08325	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
EEJ46_RS08330	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
EEJ46_RS08335	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
EEJ46_RS08340	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
EEJ46_RS08345	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
EEJ46_RS08350	COG0089	rRNA binding
EEJ46_RS08355	COG0088	Forms part of the polypeptide exit tunnel
EEJ46_RS08360	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
EEJ46_RS08365	COG0051	transcription antitermination factor activity, RNA binding
EEJ46_RS08370	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
EEJ46_RS08375	COG0049	tRNA binding
EEJ46_RS08380	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
EEJ46_RS08385	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
EEJ46_RS08390	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
EEJ46_RS08405	COG0542	response to heat
EEJ46_RS08410	COG4463	regulation of RNA biosynthetic process
EEJ46_RS08450	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
EEJ46_RS08455	COG1428	Deoxynucleoside kinase
EEJ46_RS08465	COG0833	amino acid
EEJ46_RS08470	COG0028	Belongs to the TPP enzyme family
EEJ46_RS08475	COG1959	2 iron, 2 sulfur cluster binding
EEJ46_RS08495	COG1316	TRANSCRIPTIONal
EEJ46_RS08505	COG2966	Psort location CytoplasmicMembrane, score
EEJ46_RS08510	COG1278	Cold shock
EEJ46_RS08530	COG2814	Major facilitator Superfamily
EEJ46_RS08580	COG0367	asparagine synthase
EEJ46_RS08585	COG0527	aspartate kinase activity
EEJ46_RS08590	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
EEJ46_RS08640	COG0640	Transcriptional regulator
EEJ46_RS08645	COG0564	pseudouridine synthase activity
EEJ46_RS08650	COG0514	ATP-dependent DNA helicase (RecQ)
EEJ46_RS08670	COG4690	dipeptidase activity
EEJ46_RS08675	COG2502	aspartate--ammonia ligase
EEJ46_RS08680	COG0017	Asparaginyl-tRNA synthetase
EEJ46_RS08685	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
EEJ46_RS08695	COG1053	succinate dehydrogenase
EEJ46_RS08715	COG0572	uridine kinase
EEJ46_RS08760	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
EEJ46_RS08765	COG0308	aminopeptidase N
EEJ46_RS08795	COG1302	Protein conserved in bacteria
EEJ46_RS08810	COG2261	transglycosylase associated protein
EEJ46_RS08815	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
EEJ46_RS08815	COG2755	lipolytic protein G-D-S-L family
EEJ46_RS08830	COG2814	Major facilitator Superfamily
EEJ46_RS08835	COG1733	regulation of RNA biosynthetic process
EEJ46_RS08840	COG1266	CAAX protease self-immunity
EEJ46_RS08850	COG1396	sequence-specific DNA binding
EEJ46_RS08860	COG0518	GMP synthase (glutamine-hydrolyzing) activity
EEJ46_RS08860	COG0519	Catalyzes the synthesis of GMP from XMP
EEJ46_RS08865	COG1072	(Pantothenic acid kinase))
EEJ46_RS08870	COG2070	2-Nitropropane dioxygenase
EEJ46_RS08875	COG3973	AAA domain
EEJ46_RS08880	COG0586	Pfam SNARE associated Golgi protein
EEJ46_RS08885	COG0456	acetyltransferase
EEJ46_RS08885	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
EEJ46_RS08890	COG0569	domain protein
EEJ46_RS08890	COG0475	glutathione-regulated potassium exporter activity
EEJ46_RS08895	COG0588	phosphoglycerate mutase activity
EEJ46_RS08910	COG2076	Multidrug Resistance protein
EEJ46_RS08920	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
EEJ46_RS08950	COG1846	Transcriptional regulator
EEJ46_RS08960	COG0531	amino acid
EEJ46_RS08965	COG3394	polysaccharide catabolic process
EEJ46_RS08970	COG1263	PTS System
EEJ46_RS08970	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EEJ46_RS08980	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EEJ46_RS08980	COG2190	(PTS) system
EEJ46_RS08980	COG1263	PTS System
EEJ46_RS08985	COG0765	amino acid transport
EEJ46_RS08990	COG0765	amino acid transport
EEJ46_RS08995	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EEJ46_RS09015	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EEJ46_RS09025	COG0546	phosphoglycolate phosphatase activity
EEJ46_RS09040	COG0735	belongs to the Fur family
EEJ46_RS09045	COG0194	GDP metabolic process
EEJ46_RS09070	COG0531	amino acid
EEJ46_RS09085	COG2936	dipeptidyl-peptidase activity
EEJ46_RS09090	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
EEJ46_RS09090	COG2755	lipolytic protein G-D-S-L family
EEJ46_RS09100	COG2267	carboxylic ester hydrolase activity
EEJ46_RS09105	COG0028	Belongs to the TPP enzyme family
EEJ46_RS09110	COG0196	riboflavin kinase activity
EEJ46_RS09115	COG0028	Belongs to the TPP enzyme family
EEJ46_RS09120	COG2252	PERMEase
EEJ46_RS09135	COG3475	LICD family
EEJ46_RS09145	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
EEJ46_RS09150	COG0248	Ppx GppA phosphatase
EEJ46_RS09155	COG0477	Major facilitator Superfamily
EEJ46_RS09170	COG1393	Belongs to the ArsC family
EEJ46_RS09185	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
EEJ46_RS09200	COG0778	Nitroreductase
EEJ46_RS09215	COG2017	converts alpha-aldose to the beta-anomer
EEJ46_RS09225	COG0561	phosphatase activity
EEJ46_RS09235	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
EEJ46_RS09240	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EEJ46_RS09265	COG0025	NhaP-type Na H and K H
EEJ46_RS09270	COG0812	UDP-N-acetylmuramate dehydrogenase activity
EEJ46_RS09280	COG0708	Exodeoxyribonuclease III
EEJ46_RS09295	COG0802	atpase or kinase
EEJ46_RS09300	COG0280	phosphate acetyltransferase
EEJ46_RS09305	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
EEJ46_RS09310	COG0561	phosphatase activity
EEJ46_RS09320	COG1126	abc transporter atp-binding protein
EEJ46_RS09325	COG0765	amino acid transport
EEJ46_RS09335	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
EEJ46_RS09340	COG0557	exoribonuclease II activity
EEJ46_RS09350	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
EEJ46_RS09355	COG0038	chloride channel
EEJ46_RS09370	COG0148	phosphopyruvate hydratase activity
EEJ46_RS09375	COG0149	triose-phosphate isomerase activity
EEJ46_RS09380	COG0126	phosphoglycerate kinase activity
EEJ46_RS09390	COG2390	Transcriptional regulator
EEJ46_RS09395	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
EEJ46_RS09405	COG0740	serine-type endopeptidase activity
EEJ46_RS09410	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EEJ46_RS09420	COG1481	regulation of sporulation
EEJ46_RS09430	COG1660	Displays ATPase and GTPase activities
EEJ46_RS09440	COG0165	Argininosuccinate lyase
EEJ46_RS09445	COG0137	argininosuccinate synthase activity
EEJ46_RS09450	COG1854	S-ribosylhomocysteine lyase activity
EEJ46_RS09455	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
EEJ46_RS09460	COG0556	nucleotide-excision repair
EEJ46_RS09470	COG2814	Major facilitator Superfamily
EEJ46_RS09480	COG0446	pyridine nucleotide-disulphide oxidoreductase
EEJ46_RS09490	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EEJ46_RS09500	COG2323	membrane
EEJ46_RS09505	COG0492	ferredoxin-NADP+ reductase activity
EEJ46_RS09510	COG0446	pyridine nucleotide-disulphide oxidoreductase
EEJ46_RS09520	COG1210	Utp--glucose-1-phosphate uridylyltransferase
EEJ46_RS09525	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
EEJ46_RS09530	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
EEJ46_RS09535	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
EEJ46_RS09540	COG1950	PFAM Membrane protein of
EEJ46_RS09545	COG1983	PspC domain protein
EEJ46_RS09550	COG0704	Plays a role in the regulation of phosphate uptake
EEJ46_RS09555	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
EEJ46_RS09560	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
EEJ46_RS09565	COG0581	inorganic phosphate transmembrane transporter activity
EEJ46_RS09570	COG0573	inorganic phosphate transmembrane transporter activity
EEJ46_RS09575	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
EEJ46_RS09580	COG5002	protein histidine kinase activity
EEJ46_RS09585	COG0745	RESPONSE REGULATOR receiver
EEJ46_RS09600	COG0653	protein targeting
EEJ46_RS09615	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
EEJ46_RS09620	COG1739	Uncharacterized protein family UPF0029
EEJ46_RS09625	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
EEJ46_RS09630	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EEJ46_RS09635	COG0531	amino acid
EEJ46_RS09640	COG0459	protein refolding
EEJ46_RS09645	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
EEJ46_RS09655	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
EEJ46_RS09660	COG0488	(ABC) transporter
EEJ46_RS09675	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
EEJ46_RS09680	COG0456	acetyltransferase
EEJ46_RS09685	COG0456	acetyltransferase
EEJ46_RS09690	COG1214	PFAM Peptidase M22, glycoprotease
EEJ46_RS09700	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
EEJ46_RS09710	COG3639	organic phosphonate transmembrane transporter activity
EEJ46_RS09715	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EEJ46_RS09720	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
EEJ46_RS09725	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
EEJ46_RS09740	COG4467	Involved in initiation control of chromosome replication
EEJ46_RS09745	COG0470	DNA polymerase III
EEJ46_RS09750	COG3870	Protein conserved in bacteria
EEJ46_RS09755	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
EEJ46_RS09780	COG3711	transcriptional antiterminator
EEJ46_RS09790	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
EEJ46_RS09795	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
EEJ46_RS09800	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
EEJ46_RS09815	COG2813	Specifically methylates the guanine in position
EEJ46_RS09820	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
EEJ46_RS09825	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EEJ46_RS09835	COG1611	Belongs to the LOG family
EEJ46_RS09860	COG0222	ribosome binding
EEJ46_RS09865	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
EEJ46_RS09870	COG0081	regulation of translation
EEJ46_RS09875	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
EEJ46_RS09885	COG0250	Participates in transcription elongation, termination and antitermination
EEJ46_RS09895	COG0267	Belongs to the bacterial ribosomal protein bL33 family
EEJ46_RS09910	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EEJ46_RS09915	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
EEJ46_RS09920	COG0215	cysteine-tRNA ligase activity
EEJ46_RS09950	COG0756	dUTP diphosphatase activity
EEJ46_RS09960	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
EEJ46_RS09975	COG0588	phosphoglycerate mutase activity
EEJ46_RS09990	COG1316	TRANSCRIPTIONal
EEJ46_RS09995	COG0825	malonyl-CoA metabolic process
EEJ46_RS10005	COG0439	Biotin carboxylase
EEJ46_RS10015	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EEJ46_RS10020	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
EEJ46_RS10020	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EEJ46_RS10025	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EEJ46_RS10025	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
EEJ46_RS10030	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
EEJ46_RS10030	COG3933	PFAM sigma-54 factor interaction domain-containing protein
EEJ46_RS10040	COG3716	PTS system mannose fructose sorbose family IID component
EEJ46_RS10045	COG3715	PTS system
EEJ46_RS10085	COG0083	homoserine kinase activity
EEJ46_RS10090	COG0460	homoserine dehydrogenase
EEJ46_RS10095	COG3091	SprT-like family
EEJ46_RS10100	COG2183	response to ionizing radiation
EEJ46_RS10115	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
EEJ46_RS10120	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
EEJ46_RS10130	COG2188	Transcriptional regulator
EEJ46_RS10140	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EEJ46_RS10190	COG3104	oligopeptide transport
EEJ46_RS10230	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
EEJ46_RS10235	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EEJ46_RS10240	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
EEJ46_RS10255	COG0037	tRNA processing
EEJ46_RS10260	COG1098	S1 RNA binding domain
EEJ46_RS10270	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
EEJ46_RS10275	COG2244	polysaccharide biosynthetic process
EEJ46_RS10280	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
EEJ46_RS10285	COG0193	aminoacyl-tRNA hydrolase activity
EEJ46_RS10290	COG0039	L-malate dehydrogenase activity
EEJ46_RS10310	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
EEJ46_RS10315	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
EEJ46_RS10320	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
EEJ46_RS10325	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
EEJ46_RS10330	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
EEJ46_RS10335	COG0505	Belongs to the CarA family
EEJ46_RS10340	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
EEJ46_RS10360	COG3158	transport of potassium into the cell
EEJ46_RS10365	COG2337	Toxic component of a toxin-antitoxin (TA) module
EEJ46_RS10370	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
EEJ46_RS10375	COG0736	holo-[acyl-carrier-protein] synthase activity
EEJ46_RS10395	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
EEJ46_RS10405	COG0501	Belongs to the peptidase M48B family
EEJ46_RS10410	COG1704	LemA family
EEJ46_RS10415	COG3764	Sortase (surface protein transpeptidase)
EEJ46_RS10425	COG0254	rRNA binding
EEJ46_RS10430	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
EEJ46_RS10435	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
EEJ46_RS10450	COG1760	l-serine dehydratase
EEJ46_RS10455	COG1760	l-serine dehydratase
EEJ46_RS10465	COG0814	amino acid
EEJ46_RS10470	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
EEJ46_RS10475	COG0504	CTP synthase activity
EEJ46_RS10480	COG3343	RNA polymerase activity
EEJ46_RS10490	COG0095	Lipoate-protein ligase
EEJ46_RS10495	COG1078	dGTPase activity
EEJ46_RS10515	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
EEJ46_RS10525	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
EEJ46_RS10530	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
EEJ46_RS10555	COG1108	ABC-type Mn2 Zn2 transport systems permease components
EEJ46_RS10555	COG1321	iron dependent repressor
EEJ46_RS10560	COG1121	(ABC) transporter
EEJ46_RS10565	COG1073	alpha beta
EEJ46_RS10575	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
EEJ46_RS10580	COG4466	Protein conserved in bacteria
EEJ46_RS10585	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
EEJ46_RS10590	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
EEJ46_RS10595	COG0084	hydrolase, TatD family'
EEJ46_RS10600	COG2814	Major facilitator Superfamily
EEJ46_RS10605	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EEJ46_RS10605	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EEJ46_RS10615	COG1801	Protein of unknown function DUF72
EEJ46_RS10620	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
EEJ46_RS10635	COG0248	Ppx GppA phosphatase
EEJ46_RS10650	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EEJ46_RS10660	COG1940	carbohydrate kinase activity
EEJ46_RS10665	COG2723	6-phospho-beta-galactosidase activity
EEJ46_RS10670	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EEJ46_RS10685	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EEJ46_RS10690	COG2188	Transcriptional regulator
EEJ46_RS10695	COG0180	Tryptophanyl-tRNA synthetase
EEJ46_RS10700	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EEJ46_RS10705	COG3973	AAA domain
EEJ46_RS10740	COG2274	protein secretion by the type I secretion system
EEJ46_RS10765	COG3279	Response regulator of the LytR AlgR family
EEJ46_RS10845	COG1114	Component of the transport system for branched-chain amino acids
EEJ46_RS10850	COG0561	phosphatase activity
EEJ46_RS10860	COG0561	phosphatase activity
EEJ46_RS10870	COG0110	maltose O-acetyltransferase activity
EEJ46_RS10970	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
EEJ46_RS10980	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
EEJ46_RS10990	COG1125	glycine betaine transport
EEJ46_RS11010	COG0300	oxidoreductase activity
EEJ46_RS11040	COG1881	PFAM PEBP family protein
EEJ46_RS11045	COG3759	membrane
EEJ46_RS11055	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
EEJ46_RS11075	COG0004	ammonium transporteR
EEJ46_RS11080	COG2814	Major facilitator Superfamily
EEJ46_RS11095	COG1134	teichoic acid transport
EEJ46_RS11100	COG1682	transport, permease protein
EEJ46_RS11110	COG0436	Aminotransferase
EEJ46_RS11115	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
EEJ46_RS11120	COG2011	ABC-type metal ion transport system permease component
EEJ46_RS11145	COG1268	BioY protein
EEJ46_RS11180	COG1454	alcohol dehydrogenase
EEJ46_RS11180	COG1012	belongs to the aldehyde dehydrogenase family
EEJ46_RS11190	COG1131	(ABC) transporter
EEJ46_RS11195	COG1725	Transcriptional regulator
EEJ46_RS11225	COG3842	ATPase activity
EEJ46_RS11265	COG1252	NADH dehydrogenase
EEJ46_RS11270	COG1846	Transcriptional regulator
EEJ46_RS11280	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
EEJ46_RS11310	COG3942	CHAP domain
EEJ46_RS11310	COG1388	LysM domain
EEJ46_RS11315	COG0741	lytic transglycosylase activity
EEJ46_RS11330	COG1136	(ABC) transporter
EEJ46_RS11335	COG0577	efflux transmembrane transporter activity
EEJ46_RS11345	COG2818	Glycosylase
EEJ46_RS11350	COG2409	Drug exporters of the RND superfamily
EEJ46_RS11350	COG2409	Drug exporters of the RND superfamily
EEJ46_RS11350	COG1033	growth of symbiont in host cell
EEJ46_RS11350	COG1033	growth of symbiont in host cell
EEJ46_RS11360	COG2357	RelA SpoT domain protein
EEJ46_RS11370	COG0277	FAD linked oxidase domain protein
EEJ46_RS11375	COG1316	TRANSCRIPTIONal
EEJ46_RS11390	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EEJ46_RS11395	COG1737	Transcriptional regulator
EEJ46_RS11405	COG0745	RESPONSE REGULATOR receiver
EEJ46_RS11410	COG5002	protein histidine kinase activity
EEJ46_RS11420	COG2814	Major facilitator Superfamily
EEJ46_RS11440	COG1914	H( )-stimulated, divalent metal cation uptake system
EEJ46_RS11445	COG1309	transcriptional regulator
EEJ46_RS11450	COG1959	2 iron, 2 sulfur cluster binding
EEJ46_RS11460	COG0163	prenyltransferase activity
EEJ46_RS11470	COG2190	(PTS) system
EEJ46_RS11470	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EEJ46_RS11470	COG1263	PTS System
EEJ46_RS11475	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EEJ46_RS11475	COG1263	PTS System
EEJ46_RS11475	COG2190	(PTS) system
EEJ46_RS11480	COG0366	Alpha amylase catalytic
EEJ46_RS11485	COG2188	Transcriptional regulator
EEJ46_RS11515	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
EEJ46_RS11520	COG0626	cystathionine gamma-synthase activity
EEJ46_RS11525	COG1045	serine acetyltransferase
EEJ46_RS11545	COG3964	amidohydrolase
EEJ46_RS11560	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EEJ46_RS11565	COG2188	Transcriptional regulator
EEJ46_RS11570	COG0431	NADPH-dependent FMN reductase
EEJ46_RS11600	COG3118	belongs to the thioredoxin family
EEJ46_RS11610	COG0246	Mannitol dehydrogenase
EEJ46_RS11615	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
EEJ46_RS11625	COG2213	PTS system mannitol-specific
EEJ46_RS11635	COG0363	glucosamine-6-phosphate deaminase activity
EEJ46_RS11650	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
EEJ46_RS11660	COG0386	Belongs to the glutathione peroxidase family
EEJ46_RS11670	COG4172	Belongs to the ABC transporter superfamily
EEJ46_RS11680	COG0488	(ABC) transporter
EEJ46_RS11685	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
EEJ46_RS11690	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
EEJ46_RS11720	COG0667	Aldo Keto reductase
EEJ46_RS11725	COG0406	alpha-ribazole phosphatase activity
EEJ46_RS11730	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
EEJ46_RS11735	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
EEJ46_RS11745	COG4166	transmembrane transport
EEJ46_RS11750	COG4166	transmembrane transport
EEJ46_RS11775	COG1757	Na H antiporter
EEJ46_RS11840	COG3842	ATPase activity
EEJ46_RS11855	COG3833	ABC-type maltose transport systems, permease component
EEJ46_RS11860	COG1175	transmembrane transport
EEJ46_RS11865	COG2182	Extracellular solute-binding protein
EEJ46_RS11870	COG0366	Alpha amylase catalytic
EEJ46_RS11875	COG1609	Transcriptional regulator
EEJ46_RS11880	COG1609	Transcriptional regulator
EEJ46_RS11885	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
EEJ46_RS11890	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
EEJ46_RS11895	COG1461	Dihydroxyacetone kinase
EEJ46_RS11900	COG2376	Dihydroxyacetone kinase
EEJ46_RS11905	COG2376	Dihydroxyacetone kinase
EEJ46_RS11910	COG1309	transcriptional regulator
EEJ46_RS11915	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
EEJ46_RS11920	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
EEJ46_RS11935	COG1131	(ABC) transporter
EEJ46_RS11940	COG1028	Short-chain dehydrogenase reductase Sdr
EEJ46_RS11965	COG2188	Transcriptional regulator
EEJ46_RS11975	COG4720	Psort location CytoplasmicMembrane, score
EEJ46_RS11980	COG1122	ATPase activity
EEJ46_RS11985	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
EEJ46_RS12015	COG0667	Aldo Keto reductase
EEJ46_RS12020	COG0656	L-ascorbic acid biosynthetic process
EEJ46_RS12025	COG2807	transmembrane transport
EEJ46_RS12030	COG0640	Transcriptional regulator
EEJ46_RS12065	COG1983	PspC domain protein
EEJ46_RS12090	COG1518	maintenance of DNA repeat elements
EEJ46_RS12095	COG3513	CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
EEJ46_RS12100	COG2267	carboxylic ester hydrolase activity
EEJ46_RS12110	COG1113	amino acid transport
EEJ46_RS12125	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
EEJ46_RS12135	COG0352	thiamine-phosphate diphosphorylase activity
EEJ46_RS12140	COG0351	phosphomethylpyrimidine kinase
EEJ46_RS12145	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
EEJ46_RS12155	COG1606	tRNA processing
EEJ46_RS12160	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
EEJ46_RS12165	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
EEJ46_RS12170	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
EEJ46_RS12175	COG1691	(AIR) carboxylase
EEJ46_RS12180	COG3875	lactate racemase activity
EEJ46_RS12185	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EEJ46_RS12190	COG0310	cobalt ion transport
EEJ46_RS12195	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
EEJ46_RS12200	COG1122	ATPase activity
EEJ46_RS12225	COG4166	transmembrane transport
EEJ46_RS12240	COG2267	carboxylic ester hydrolase activity
EEJ46_RS12265	COG0604	alcohol dehydrogenase
EEJ46_RS12300	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
EEJ46_RS12320	COG2368	4-hydroxyphenylacetate
EEJ46_RS12325	COG2365	Tyrosine phosphatase family
EEJ46_RS12335	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
EEJ46_RS12340	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EEJ46_RS12350	COG2508	Transcriptional regulator
EEJ46_RS12355	COG0778	Nitroreductase
EEJ46_RS12365	COG1028	Short-chain dehydrogenase reductase Sdr
EEJ46_RS12370	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
EEJ46_RS12385	COG0471	metal ion transport
EEJ46_RS12390	COG1053	succinate dehydrogenase
EEJ46_RS12390	COG3976	FMN-binding domain protein
EEJ46_RS12390	COG0431	NADPH-dependent FMN reductase
EEJ46_RS12410	COG1573	uracil-dna glycosylase
EEJ46_RS12425	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
EEJ46_RS12430	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EEJ46_RS12435	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
EEJ46_RS12440	COG4853	Protein conserved in bacteria
EEJ46_RS12450	COG5002	protein histidine kinase activity
EEJ46_RS12455	COG0745	RESPONSE REGULATOR receiver
EEJ46_RS12470	COG1278	Cold shock
EEJ46_RS12480	COG1554	hydrolase, family 65, central catalytic
EEJ46_RS12485	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EEJ46_RS12495	COG3103	Sh3 type 3 domain protein
EEJ46_RS12495	COG0366	Alpha amylase catalytic
EEJ46_RS12500	COG0058	SHG alpha-glucan phosphorylase activity
EEJ46_RS12505	COG0297	glycogen (starch) synthase activity
EEJ46_RS12510	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
EEJ46_RS12515	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
EEJ46_RS12520	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
EEJ46_RS12525	COG4166	transmembrane transport
EEJ46_RS12530	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
EEJ46_RS12535	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
EEJ46_RS12540	COG2814	Major facilitator Superfamily
EEJ46_RS12545	COG0305	Participates in initiation and elongation during chromosome replication
EEJ46_RS12550	COG0359	binds to the 23S rRNA
EEJ46_RS12560	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
EEJ46_RS12565	COG0629	single-stranded DNA binding
EEJ46_RS12570	COG0360	Binds together with S18 to 16S ribosomal RNA
EEJ46_RS12580	COG0187	DNA topoisomerase II activity
EEJ46_RS12585	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
EEJ46_RS12590	COG2501	S4 domain
EEJ46_RS12595	COG0592	DNA-directed DNA polymerase activity
EEJ46_RS12600	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
EEJ46_RS12605	COG0230	Belongs to the bacterial ribosomal protein bL34 family
EEJ46_RS12610	COG0594	ribonuclease P activity
EEJ46_RS12615	COG0706	membrane insertase activity
EEJ46_RS12620	COG4166	transmembrane transport
EEJ46_RS12630	COG1847	R3H domain protein
EEJ46_RS12635	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
EEJ46_RS12640	COG0445	tRNA wobble uridine modification
EEJ46_RS12680	COG1307	EDD domain protein, DegV family
EEJ46_RS12695	COG3479	Phenolic acid decarboxylase
EEJ46_RS12700	COG1695	Transcriptional regulator
EEJ46_RS12710	COG1454	alcohol dehydrogenase
EEJ46_RS12710	COG1012	belongs to the aldehyde dehydrogenase family
EEJ46_RS12730	COG1869	D-ribose catabolic process
EEJ46_RS12735	COG4975	Glucose uptake
EEJ46_RS12755	COG3730	PTS system glucitol sorbitol-specific
EEJ46_RS12760	COG3732	PTS system glucitol sorbitol-specific
EEJ46_RS12775	COG2188	Transcriptional regulator
EEJ46_RS12780	COG1132	(ABC) transporter
EEJ46_RS12785	COG1132	(ABC) transporter
EEJ46_RS12790	COG2207	Transcriptional regulator
EEJ46_RS12790	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EEJ46_RS12805	COG0395	ABC-type sugar transport system, permease component
EEJ46_RS12810	COG1653	transport
EEJ46_RS12815	COG0366	Alpha amylase catalytic
EEJ46_RS12825	COG2972	Histidine kinase
EEJ46_RS12830	COG4753	response regulator
EEJ46_RS12830	COG2207	Transcriptional regulator
EEJ46_RS12840	COG3842	ATPase activity
EEJ46_RS12850	COG2188	Transcriptional regulator
EEJ46_RS12860	COG0383	alpha-mannosidase activity
EEJ46_RS12865	COG2723	6-phospho-beta-galactosidase activity
EEJ46_RS12875	COG1349	DNA-binding transcription factor activity
EEJ46_RS12880	COG2207	Transcriptional regulator
EEJ46_RS12885	COG2814	Major facilitator Superfamily
EEJ46_RS12890	COG1070	Carbohydrate kinase
EEJ46_RS12895	COG3254	rhamnose metabolic process
EEJ46_RS12900	COG4806	L-rhamnose isomerase
EEJ46_RS12905	COG0235	Class ii aldolase
EEJ46_RS12920	COG0028	Belongs to the TPP enzyme family
EEJ46_RS12925	COG1959	2 iron, 2 sulfur cluster binding
EEJ46_RS12930	COG0028	Belongs to the TPP enzyme family
EEJ46_RS12935	COG1304	FMN binding
EEJ46_RS12950	COG4512	PFAM Accessory gene regulator B
EEJ46_RS12970	COG1393	Belongs to the ArsC family
EEJ46_RS12980	COG2261	transglycosylase associated protein
EEJ46_RS13010	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
EEJ46_RS13015	COG1609	Transcriptional regulator
EEJ46_RS13035	COG2160	L-arabinose isomerase activity
EEJ46_RS13040	COG0110	maltose O-acetyltransferase activity
EEJ46_RS13050	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
EEJ46_RS13055	COG1349	DNA-binding transcription factor activity
EEJ46_RS13070	COG3775	system Galactitol-specific IIC component
EEJ46_RS13085	COG3711	transcriptional antiterminator
EEJ46_RS13105	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
EEJ46_RS13120	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
EEJ46_RS13135	COG2211	Major facilitator Superfamily
EEJ46_RS13155	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EEJ46_RS13155	COG2190	(PTS) system
EEJ46_RS13155	COG1263	PTS System
EEJ46_RS13160	COG2723	6-phospho-beta-galactosidase activity
EEJ46_RS13165	COG2723	6-phospho-beta-galactosidase activity
EEJ46_RS13175	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
EEJ46_RS13180	COG1263	PTS System
EEJ46_RS13180	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EEJ46_RS13185	COG1737	Transcriptional regulator
EEJ46_RS13190	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EEJ46_RS13190	COG2190	(PTS) system
EEJ46_RS13190	COG1263	PTS System
EEJ46_RS13195	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EEJ46_RS13195	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EEJ46_RS13195	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EEJ46_RS13200	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EEJ46_RS13200	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EEJ46_RS13205	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
EEJ46_RS13215	COG3711	transcriptional antiterminator
EEJ46_RS13225	COG2723	6-phospho-beta-galactosidase activity
EEJ46_RS13235	COG2971	BadF BadG BcrA BcrD
EEJ46_RS13240	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
EEJ46_RS13245	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EEJ46_RS13250	COG2188	Transcriptional regulator
EEJ46_RS13255	COG2267	carboxylic ester hydrolase activity
EEJ46_RS13265	COG2271	Major facilitator Superfamily
EEJ46_RS13280	COG1028	Short-chain dehydrogenase reductase Sdr
EEJ46_RS13295	COG2271	Major facilitator Superfamily
EEJ46_RS13300	COG0583	DNA-binding transcription factor activity
EEJ46_RS13305	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
EEJ46_RS13310	COG0710	3-dehydroquinate dehydratase activity
EEJ46_RS13330	COG0667	Aldo Keto reductase
EEJ46_RS13335	COG1609	Transcriptional regulator
EEJ46_RS13340	COG2017	converts alpha-aldose to the beta-anomer
EEJ46_RS13345	COG2211	Major facilitator Superfamily
EEJ46_RS13345	COG2190	(PTS) system
EEJ46_RS13365	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
EEJ46_RS13370	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
EEJ46_RS13375	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
EEJ46_RS13380	COG1609	Transcriptional regulator
EEJ46_RS13385	COG2944	sequence-specific DNA binding
EEJ46_RS13390	COG2184	nucleotidyltransferase activity
EEJ46_RS13410	COG0477	Major facilitator Superfamily
EEJ46_RS13420	COG1609	Transcriptional regulator
EEJ46_RS13425	COG1874	Beta-galactosidase
EEJ46_RS13435	COG1114	Component of the transport system for branched-chain amino acids
EEJ46_RS13450	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
EEJ46_RS13500	COG0446	pyridine nucleotide-disulphide oxidoreductase
EEJ46_RS13525	COG3590	peptidase
EEJ46_RS13530	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EEJ46_RS13550	COG1937	Protein conserved in bacteria
EEJ46_RS13555	COG3118	belongs to the thioredoxin family
EEJ46_RS13560	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
EEJ46_RS13565	COG2217	Heavy metal translocating P-type atpase
EEJ46_RS13590	COG2226	methyltransferase
EEJ46_RS13600	COG1309	transcriptional regulator
EEJ46_RS13660	COG0076	glutamate decarboxylase activity
EEJ46_RS13685	COG2207	Transcriptional regulator
EEJ46_RS13720	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
EEJ46_RS13725	COG1968	undecaprenyl-diphosphatase activity
EEJ46_RS13745	COG0656	L-ascorbic acid biosynthetic process
EEJ46_RS13755	COG0737	Belongs to the 5'-nucleotidase family
EEJ46_RS13815	COG0477	Major facilitator Superfamily
EEJ46_RS13840	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
EEJ46_RS13855	COG0697	spore germination
EEJ46_RS13875	COG0071	Belongs to the small heat shock protein (HSP20) family
EEJ46_RS13890	COG1194	a g-specific adenine glycosylase
EEJ46_RS13900	COG3189	MarR family transcriptional regulator
EEJ46_RS13905	COG1393	Belongs to the ArsC family
EEJ46_RS13920	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
EEJ46_RS13930	COG1113	amino acid transport
EEJ46_RS13935	COG1757	Na H antiporter
EEJ46_RS13945	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
EEJ46_RS13950	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
EEJ46_RS13960	COG2315	Protein conserved in bacteria
EEJ46_RS13970	COG2217	Heavy metal translocating P-type atpase
EEJ46_RS14005	COG4989	oxidoreductase activity
EEJ46_RS14010	COG2151	metal-sulfur cluster biosynthetic enzyme
EEJ46_RS14020	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
EEJ46_RS14025	COG1882	Formate acetyltransferase
EEJ46_RS14030	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EEJ46_RS14060	COG2814	Major facilitator Superfamily
EEJ46_RS14065	COG0803	Belongs to the bacterial solute-binding protein 9 family
EEJ46_RS14085	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
EEJ46_RS14090	COG0302	gtp cyclohydrolase
EEJ46_RS14100	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
EEJ46_RS14135	COG0640	Transcriptional regulator
EEJ46_RS14140	COG1272	protein, Hemolysin III
EEJ46_RS14160	COG0628	permease
EEJ46_RS14165	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
EEJ46_RS14170	COG3158	transport of potassium into the cell
EEJ46_RS14175	COG0531	amino acid
EEJ46_RS14185	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EEJ46_RS14190	COG2365	Tyrosine phosphatase family
EEJ46_RS14200	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
EEJ46_RS14205	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
EEJ46_RS14220	COG1929	Belongs to the glycerate kinase type-1 family
EEJ46_RS14230	COG1562	ergosterol biosynthetic process
EEJ46_RS14235	COG1233	COG1233 Phytoene dehydrogenase and related
EEJ46_RS14240	COG2738	Putative neutral zinc metallopeptidase
EEJ46_RS14250	COG1307	EDD domain protein, DegV family
EEJ46_RS14260	COG1380	Effector of murein hydrolase LrgA
EEJ46_RS14285	COG0735	belongs to the Fur family
EEJ46_RS14315	COG1263	PTS System
EEJ46_RS14315	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EEJ46_RS14315	COG2190	(PTS) system
EEJ46_RS14330	COG3711	transcriptional antiterminator
EEJ46_RS14330	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EEJ46_RS14335	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EEJ46_RS14335	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EEJ46_RS14335	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EEJ46_RS14340	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EEJ46_RS14345	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EEJ46_RS14345	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EEJ46_RS14345	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EEJ46_RS14350	COG0383	alpha-mannosidase activity
EEJ46_RS14360	COG0561	phosphatase activity
EEJ46_RS14375	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
EEJ46_RS14380	COG4619	ABC transporter
EEJ46_RS14385	COG0390	transport system, permease component
EEJ46_RS14400	COG1609	Transcriptional regulator
EEJ46_RS14405	COG0366	Alpha amylase catalytic
EEJ46_RS14410	COG2190	(PTS) system
EEJ46_RS14410	COG1263	PTS System
EEJ46_RS14410	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EEJ46_RS14435	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EEJ46_RS14440	COG1126	abc transporter atp-binding protein
EEJ46_RS14445	COG0765	amino acid transport
EEJ46_RS14450	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EEJ46_RS14455	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EEJ46_RS14460	COG0583	DNA-binding transcription factor activity
EEJ46_RS14475	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EEJ46_RS14480	COG0357	Ribosomal RNA small subunit methyltransferase G
EEJ46_RS14490	COG1192	Involved in chromosome partitioning
EEJ46_RS14495	COG1475	DNA binding
EEJ46_RS14500	COG4481	Protein conserved in bacteria
EEJ46_RS14505	COG0012	GTP binding
EEJ46_RS14515	COG0516	GMP reductase activity
EEJ46_RS14515	COG0517	IMP dehydrogenase activity
EEJ46_RS14520	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EEJ46_RS14540	COG1686	Belongs to the peptidase S11 family
EEJ46_RS14545	COG1247	-acetyltransferase
EEJ46_RS14585	COG0515	serine threonine protein kinase
EEJ46_RS14585	COG2815	serine threonine protein kinase
EEJ46_RS14595	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
EEJ46_RS14605	COG1846	Transcriptional regulator
EEJ46_RS14605	COG1940	carbohydrate kinase activity
EEJ46_RS14610	COG0628	permease
EEJ46_RS14615	COG0588	phosphoglycerate mutase activity
EEJ46_RS14640	COG0477	Major facilitator Superfamily
EEJ46_RS14655	COG0656	L-ascorbic acid biosynthetic process
EEJ46_RS14660	COG1376	ErfK ybiS ycfS ynhG family protein
EEJ46_RS14680	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
EEJ46_RS14690	COG1733	regulation of RNA biosynthetic process
EEJ46_RS14725	COG0789	Transcriptional regulator
EEJ46_RS14745	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EEJ46_RS14750	COG2723	6-phospho-beta-galactosidase activity
EEJ46_RS14760	COG0783	Belongs to the Dps family
EEJ46_RS14770	COG0431	NADPH-dependent FMN reductase
EEJ46_RS14770	COG1053	succinate dehydrogenase
EEJ46_RS14770	COG3976	FMN-binding domain protein
EEJ46_RS14780	COG2816	NAD+ diphosphatase activity
EEJ46_RS14790	COG0481	GTPase activity
EEJ46_RS14830	COG1028	Short-chain dehydrogenase reductase Sdr
EEJ46_RS14835	COG0110	maltose O-acetyltransferase activity
EEJ46_RS14840	COG4221	oxidoreductase activity
EEJ46_RS14850	COG1309	transcriptional regulator
EEJ46_RS14855	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EEJ46_RS14860	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EEJ46_RS14865	COG1120	ATPase activity
EEJ46_RS14870	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EEJ46_RS14880	COG0477	Major facilitator Superfamily
EEJ46_RS14895	COG0667	Aldo Keto reductase
EEJ46_RS14910	COG0300	oxidoreductase activity
EEJ46_RS14915	COG1733	regulation of RNA biosynthetic process
EEJ46_RS14930	COG1012	belongs to the aldehyde dehydrogenase family
EEJ46_RS14940	COG1309	transcriptional regulator
EEJ46_RS14955	COG3279	Response regulator of the LytR AlgR family
EEJ46_RS14960	COG0367	asparagine synthase
EEJ46_RS14970	COG2814	Major facilitator Superfamily
EEJ46_RS14975	COG1733	regulation of RNA biosynthetic process
EEJ46_RS14980	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EEJ46_RS15020	COG1063	alcohol dehydrogenase
EEJ46_RS15025	COG0300	oxidoreductase activity
EEJ46_RS15085	COG2217	Heavy metal translocating P-type atpase
EEJ46_RS15115	COG0531	amino acid
EEJ46_RS15130	COG1028	Short-chain dehydrogenase reductase Sdr
EEJ46_RS15135	COG1473	amidohydrolase
EEJ46_RS15145	COG1132	(ABC) transporter
EEJ46_RS15150	COG1132	(ABC) transporter
EEJ46_RS15165	COG1028	Short-chain dehydrogenase reductase Sdr
EEJ46_RS15195	COG4221	oxidoreductase activity
EEJ46_RS15210	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EEJ46_RS15235	COG0803	Belongs to the bacterial solute-binding protein 9 family
EEJ46_RS15255	COG0741	lytic transglycosylase activity
EEJ46_RS15260	COG0789	Transcriptional regulator
EEJ46_RS15270	COG2723	6-phospho-beta-galactosidase activity
EEJ46_RS15275	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EEJ46_RS15280	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EEJ46_RS15315	COG1136	(ABC) transporter
EEJ46_RS15315	COG0577	efflux transmembrane transporter activity
EEJ46_RS15330	COG0640	Transcriptional regulator
EEJ46_RS15350	COG1914	H( )-stimulated, divalent metal cation uptake system
EEJ46_RS15360	COG2246	polysaccharide biosynthetic process
EEJ46_RS15365	COG5549	protein import
EEJ46_RS15365	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EEJ46_RS15380	COG0559	Belongs to the binding-protein-dependent transport system permease family
EEJ46_RS15395	COG0410	ABC transporter
EEJ46_RS15400	COG0617	tRNA 3'-terminal CCA addition
EEJ46_RS15400	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
EEJ46_RS15400	COG3620	sequence-specific DNA binding
EEJ46_RS15430	COG4120	Belongs to the binding-protein-dependent transport system permease family
EEJ46_RS15435	COG1116	anion transmembrane transporter activity
EEJ46_RS15440	COG2190	(PTS) system
EEJ46_RS15440	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EEJ46_RS15440	COG1263	PTS System
EEJ46_RS15445	COG0778	Nitroreductase
EEJ46_RS15455	COG1132	(ABC) transporter
EEJ46_RS15465	COG1940	carbohydrate kinase activity
EEJ46_RS15490	COG0697	spore germination
EEJ46_RS15555	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
EEJ46_RS15565	COG0583	DNA-binding transcription factor activity
EEJ46_RS15585	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EEJ46_RS15595	COG0242	peptide deformylase activity
EEJ46_RS15605	COG1328	CTP reductase activity
EEJ46_RS15615	COG2200	EAL domain
EEJ46_RS15655	COG2270	Major facilitator Superfamily
EEJ46_RS15670	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate