locus-tag	class	description
Heal19_RS00050	ENOG4105DZR	Type I site-specific deoxyribonuclease
Heal19_RS00130	ENOG4108JYZ	YitT family
Heal19_RS00145	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
Heal19_RS00155	ENOG41082QR	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
Heal19_RS00160	ENOG4105WDJ	50S ribosomal protein L33
Heal19_RS00170	ENOG41086FC	50S ribosomal protein l32
Heal19_RS00175	ENOG4108RS6	transposase
Heal19_RS00205	ENOG41080Y5	BioY family
Heal19_RS00225	ENOG4105EPR	degv family
Heal19_RS00230	ENOG4105TV1	Transcriptional regulator
Heal19_RS00235	ENOG4105QUH	Domain of unknown function (DUF2088)
Heal19_RS00240	ENOG4105DTC	1-(5-phosphoribosyl)-5-amino-4-imidazole-carboxylate (air) carboxylase
Heal19_RS00255	ENOG4105DVM	PP-loop domain protein
Heal19_RS00260	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
Heal19_RS00295	ENOG4107QJE	Chromosome Partitioning Protein
Heal19_RS00390	ENOG4105D9G	High-affinity
Heal19_RS00410	ENOG4105C56	H( )-stimulated, divalent metal cation uptake system (By similarity)
Heal19_RS00425	ENOG4105DC7	peptidase M24
Heal19_RS00430	ENOG410749K	Uncharacterized protein conserved in bacteria (DUF2179)
Heal19_RS00435	ENOG4108RCR	degv family
Heal19_RS00455	ENOG4107R8N	Glycosyl transferase, family 2
Heal19_RS00475	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
Heal19_RS00480	ENOG4105BZ1	(ABC) transporter
Heal19_RS00485	ENOG4105BZ1	(ABC) transporter
Heal19_RS00490	ENOG4105CPC	Aldo Keto reductase
Heal19_RS00500	ENOG4105C87	Aminotransferase class I and II
Heal19_RS00520	ENOG4108UW5	maltose o-acetyltransferase
Heal19_RS00525	ENOG4107YZX	Universal stress protein
Heal19_RS00535	ENOG4105WT3	Transcriptional regulator
Heal19_RS00560	ENOG4105CV8	reductase
Heal19_RS00565	ENOG4105EMU	Dehydrogenase
Heal19_RS00600	ENOG4105CSC	Glucose uptake protein
Heal19_RS00605	ENOG4107EXU	Short-chain dehydrogenase reductase Sdr
Heal19_RS00625	ENOG4107EXU	Short-chain dehydrogenase reductase Sdr
Heal19_RS00630	ENOG4105CPQ	Dehydrogenase
Heal19_RS00640	ENOG4108KB2	LysR family Transcriptional regulator
Heal19_RS00665	ENOG4108W0I	acetyltransferase
Heal19_RS00675	ENOG4105C3F	Signal peptidase i
Heal19_RS00685	ENOG4105CSM	endonuclease III
Heal19_RS00710	ENOG4105VUF	Transcriptional regulator
Heal19_RS00725	ENOG4107GJV	short-chain dehydrogenase reductase
Heal19_RS00735	ENOG4108IUX	(ABC) transporter
Heal19_RS00740	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
Heal19_RS00755	ENOG4105E2K	Glycosyl transferase (Group 1
Heal19_RS00760	ENOG4107XU6	Glycosyl transferase (Group 1
Heal19_RS00765	ENOG4105FQP	Beta-lactamase
Heal19_RS00780	ENOG4105HMI	Membrane
Heal19_RS00805	ENOG4105EQ0	Major Facilitator superfamily
Heal19_RS00810	ENOG4108IJ0	Aspartate ammonia-lyase
Heal19_RS00845	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
Heal19_RS00850	ENOG4105I2S	Part of the ABC transporter complex hrt involved in hemin import. Responsible for the translocation of the substrate across the membrane (By similarity)
Heal19_RS00870	ENOG4108UQV	Membrane
Heal19_RS00900	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
Heal19_RS00905	ENOG4105PUK	Membrane
Heal19_RS00950	ENOG4105E5D	amino acid
Heal19_RS00955	ENOG4105FF2	Type I DHQase
Heal19_RS00975	ENOG4105NQC	Flavodoxin
Heal19_RS00995	ENOG4108UZ3	Transporter
Heal19_RS01000	ENOG4108JZF	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
Heal19_RS01020	ENOG4105K64	Glycosyl transferase, family 2
Heal19_RS01025	ENOG4107414	GntR family transcriptional regulator
Heal19_RS01030	ENOG4105VZJ	PTS System
Heal19_RS01035	ENOG4105VCP	PTS System
Heal19_RS01040	ENOG4105CS2	ec 3.2.1.21
Heal19_RS01045	ENOG4105CS2	ec 3.2.1.21
Heal19_RS01050	ENOG4105BZC	d-serine deaminase
Heal19_RS01070	ENOG4105MKU	Transcriptional regulator
Heal19_RS01075	ENOG4105DAP	Nicotinate phosphoribosyltransferase
Heal19_RS01115	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
Heal19_RS01120	ENOG4108UW5	maltose o-acetyltransferase
Heal19_RS01130	ENOG410667J	hydrolase
Heal19_RS01135	ENOG4105D98	threonine synthase
Heal19_RS01140	ENOG4108IUK	alpha amylase, catalytic
Heal19_RS01160	ENOG4105C87	Aminotransferase class I and II
Heal19_RS01175	ENOG4105WH5	Teichoic acid glycosylation protein
Heal19_RS01185	ENOG4107YZX	Universal stress protein
Heal19_RS01195	ENOG4105DVE	abc transporter atp-binding protein
Heal19_RS01200	ENOG4105W8V	TRANSCRIPTIONAl REGULATOR GntR family
Heal19_RS01215	ENOG4105C19	ABC transporter
Heal19_RS01220	ENOG4105HDK	L-asparaginase
Heal19_RS01235	ENOG4105M2Z	protein tyrosine serine phosphatase
Heal19_RS01240	ENOG4105DF9	Lipoate-protein, ligase
Heal19_RS01245	ENOG4107EFR	Flavocytochrome c
Heal19_RS01250	ENOG4105C00	Succinate dehydrogenase (Flavoprotein subunit)
Heal19_RS01255	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
Heal19_RS01260	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
Heal19_RS01265	ENOG4105C8V	SAICAR synthetase
Heal19_RS01270	ENOG4105VR9	phosphoribosylformylglycinamidine synthase
Heal19_RS01275	ENOG4105D21	Phosphoribosylformylglycinamidine synthase I
Heal19_RS01280	ENOG4108JIU	phosphoribosylformylglycinamidine synthase ii
Heal19_RS01285	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
Heal19_RS01290	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
Heal19_RS01295	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
Heal19_RS01300	ENOG4105DC1	bifunctional purine biosynthesis protein purh
Heal19_RS01305	ENOG4105C12	Phosphoribosylglycinamide synthetase
Heal19_RS01315	ENOG4105CND	Glycosyl transferase, family 2
Heal19_RS01335	ENOG4105C7N	Xanthine uracil vitamin C permease
Heal19_RS01345	ENOG4105G9B	Transcriptional regulator
Heal19_RS01350	ENOG4108UK1	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant (By similarity)
Heal19_RS01355	ENOG4105CXT	aspartate transcarbamylase
Heal19_RS01360	ENOG4105CD3	dihydroorotase
Heal19_RS01365	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
Heal19_RS01370	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
Heal19_RS01375	ENOG4107RY0	Catalyzes the conversion of dihydroorotate to orotate (By similarity)
Heal19_RS01380	ENOG4106EG9	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity)
Heal19_RS01385	ENOG41065E1	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
Heal19_RS01395	ENOG4105C5N	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
Heal19_RS01400	ENOG4107R2I	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation
Heal19_RS01415	ENOG4107ZGM	malolactic fermentation system
Heal19_RS01430	ENOG4105CHM	Aminotransferase
Heal19_RS01435	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
Heal19_RS01440	ENOG4105D8W	glucose-6-phosphate 1-dehydrogenase
Heal19_RS01450	ENOG4105EE6	Alcohol dehydrogenase zinc-binding domain protein
Heal19_RS01455	ENOG4107TXC	Transcriptional regulator
Heal19_RS01460	ENOG410605W	Major Facilitator
Heal19_RS01465	ENOG4107SUZ	Sodium/hydrogen exchanger family
Heal19_RS01470	ENOG4105MTF	NrdI protein
Heal19_RS01475	ENOG4105C37	(CBS) domain
Heal19_RS01515	ENOG4108Z66	YbaK ebsC protein
Heal19_RS01520	ENOG4108TZY	GntR Family Transcriptional Regulator
Heal19_RS01525	ENOG4107UWA	esterase
Heal19_RS01530	ENOG4107QRI	Phosphoketolase
Heal19_RS01535	ENOG4105CG5	Glycosyl transferase (Group 1
Heal19_RS01550	ENOG4108YBP	pseudouridine synthase
Heal19_RS01555	ENOG4107YZX	Universal stress protein
Heal19_RS01560	ENOG4105FDP	GntR family transcriptional regulator
Heal19_RS01565	ENOG4108UZY	PTS System
Heal19_RS01570	ENOG4105ETZ	PTS System
Heal19_RS01575	ENOG4105F3R	pts system mannose fructose sorbose family iid
Heal19_RS01585	ENOG4108ZW7	flagellar rod assembly protein muramidase flgj
Heal19_RS01590	ENOG4105DF9	Lipoate-protein, ligase
Heal19_RS01605	ENOG41081I9	integral membrane protein
Heal19_RS01620	ENOG4105C28	cystathionine
Heal19_RS01630	ENOG4108MXZ	Esterase
Heal19_RS01640	ENOG4105C7K	acetolactate synthase
Heal19_RS01680	ENOG4105W8V	TRANSCRIPTIONAl REGULATOR GntR family
Heal19_RS01685	ENOG4105CZV	ABC transporter
Heal19_RS01705	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
Heal19_RS01710	ENOG4107SUZ	Sodium/hydrogen exchanger family
Heal19_RS01715	ENOG4105D9R	oxidoreductase
Heal19_RS01720	ENOG4105EE0	oxidoreductase
Heal19_RS01725	ENOG4106KNT	transcriptional regulator
Heal19_RS01745	ENOG4105DKT	Transcriptional regulator
Heal19_RS01755	ENOG4105E98	transcriptional regulator DeoR family
Heal19_RS01765	ENOG4105EZX	Catalyzes the phosphorylation of N-acetyl-D-glucosamine (GlcNAc) derived from cell-wall degradation, yielding GlcNAc-6-P (By similarity)
Heal19_RS01770	ENOG4105CSC	Glucose uptake protein
Heal19_RS01775	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
Heal19_RS01785	ENOG4108TVJ	Nitroreductase
Heal19_RS01790	ENOG4105CSR	polyphosphate kinase 2
Heal19_RS01795	ENOG4108M1Z	surface protein
Heal19_RS01805	ENOG4105CAY	ferredoxin--nadp reductase
Heal19_RS01810	ENOG4108QXE	glycerophosphoryl diester phosphodiesterase
Heal19_RS01815	ENOG4105E0M	Sulfatase
Heal19_RS01850	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
Heal19_RS01860	ENOG4105E1F	short-chain dehydrogenase reductase
Heal19_RS01865	ENOG4105VUF	Transcriptional regulator
Heal19_RS01885	ENOG4108W76	histidinol phosphate phosphatase hisj family
Heal19_RS01890	ENOG4107Z2D	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine (By similarity)
Heal19_RS01895	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
Heal19_RS01900	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
Heal19_RS01905	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
Heal19_RS01910	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
Heal19_RS01915	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
Heal19_RS01920	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
Heal19_RS01925	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
Heal19_RS01930	ENOG41083RF	phosphoribosyl-ATP pyrophosphatase
Heal19_RS01935	ENOG4105CIH	Imidazole acetol-phosphate transaminase
Heal19_RS01940	ENOG4108UW5	maltose o-acetyltransferase
Heal19_RS01945	ENOG4107TS3	membrane protein, TerC
Heal19_RS01950	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
Heal19_RS01955	ENOG4107QMW	pyridine nucleotide-disulfide oxidoreductase
Heal19_RS01965	ENOG4105C7J	ABC transporter, permease
Heal19_RS01975	ENOG4105CVG	Homoserine O-transsuccinylase
Heal19_RS01985	ENOG4105D6E	homoserine dehydrogenase
Heal19_RS01990	ENOG4105EPR	degv family
Heal19_RS01995	ENOG4108JZF	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
Heal19_RS02000	ENOG4105CI1	PTS System
Heal19_RS02010	ENOG4109025	Glyoxalase Bleomycin resistance protein (Dioxygenase
Heal19_RS02020	ENOG4105C5H	ABC transporter
Heal19_RS02025	ENOG4106TD9	Diguanylate cyclase
Heal19_RS02040	ENOG4105EW9	transcriptional regulator AsnC family
Heal19_RS02045	ENOG4107SN7	NLP P60 protein
Heal19_RS02065	ENOG41079KZ	Major Facilitator Superfamily
Heal19_RS02085	ENOG4108UZ3	Transporter
Heal19_RS02090	ENOG4105VUC	UPF0237 protein
Heal19_RS02095	ENOG4105CAG	UPF0210 protein
Heal19_RS02100	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
Heal19_RS02105	ENOG4105BZU	Histidine kinase
Heal19_RS02110	ENOG4105DR4	Methyltransferase
Heal19_RS02115	ENOG4105CSC	Glucose uptake protein
Heal19_RS02120	ENOG4107QYV	phosphohexose isomerase
Heal19_RS02130	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
Heal19_RS02140	ENOG4105BZ1	(ABC) transporter
Heal19_RS02155	ENOG4105T6C	Cell surface-associated protein implicated in virulence by promoting bacterial attachment to both alpha- and beta-chains of human fibrinogen and inducing the formation of bacterial clumps
Heal19_RS02200	ENOG4108FPN	Integrase
Heal19_RS02225	ENOG41067V3	Antibiotic biosynthesis monooxygenase
Heal19_RS02235	ENOG4105M2E	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
Heal19_RS02445	ENOG4108FKH	Transglycosylase SLT domain
Heal19_RS02485	ENOG4107BJW	polysaccharide deacetylase
Heal19_RS02500	ENOG4105BZ1	(ABC) transporter
Heal19_RS02515	ENOG4105CM2	brancheD-chain amino acid aminotransferase
Heal19_RS02525	ENOG4107S1E	Beta-lactamase
Heal19_RS02530	ENOG4105DG6	mannose-6-phosphate isomerase
Heal19_RS02535	ENOG4105F1K	Glutamine amidotransferase
Heal19_RS02540	ENOG4105DMS	mur ligase
Heal19_RS02545	ENOG4107104	thymidine kinase
Heal19_RS02550	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
Heal19_RS02555	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
Heal19_RS02560	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
Heal19_RS02565	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
Heal19_RS02570	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
Heal19_RS02585	ENOG4107RFS	it plays a direct role in the translocation of protons across the membrane (By similarity)
Heal19_RS02590	ENOG4105WS6	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
Heal19_RS02595	ENOG4107ZFM	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) (By similarity)
Heal19_RS02600	ENOG4107YZM	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
Heal19_RS02605	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
Heal19_RS02610	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
Heal19_RS02615	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
Heal19_RS02620	ENOG4105KNM	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
Heal19_RS02625	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
Heal19_RS02635	ENOG4105DFF	Rod shape-determining protein mreb
Heal19_RS02640	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
Heal19_RS02655	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
Heal19_RS02660	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
Heal19_RS02665	ENOG4108UMI	ABC transporter, permease
Heal19_RS02670	ENOG4105D01	(LipO)protein
Heal19_RS02690	ENOG4105CPF	Cell wall formation (By similarity)
Heal19_RS02710	ENOG4107YZX	Universal stress protein
Heal19_RS02725	ENOG4105D1H	recombination factor protein RarA
Heal19_RS02730	ENOG4105D9M	gamma-glutamylcysteine synthetase
Heal19_RS02735	ENOG4105ETE	Transcriptional regulator (LacI family
Heal19_RS02740	ENOG4108IQ3	PTS system
Heal19_RS02745	ENOG4105ETZ	PTS System
Heal19_RS02750	ENOG4105F3R	pts system mannose fructose sorbose family iid
Heal19_RS02765	ENOG41085FC	arsR family transcriptional regulator
Heal19_RS02780	ENOG4108WQ8	UPF0637 protein
Heal19_RS02785	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
Heal19_RS02795	ENOG4105DGY	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization (By similarity)
Heal19_RS02800	ENOG4105C3J	Cysteine desulfurase
Heal19_RS02805	ENOG4105D8I	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS (By similarity)
Heal19_RS02810	ENOG4105D9M	gamma-glutamylcysteine synthetase
Heal19_RS02820	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
Heal19_RS02825	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
Heal19_RS02830	ENOG4105W5Q	DNA repair protein (RadC
Heal19_RS02835	ENOG4105DFF	Rod shape-determining protein mreb
Heal19_RS02840	ENOG4105N3I	Involved in formation and maintenance of cell shape (By similarity)
Heal19_RS02855	ENOG4107QMS	site-determining protein
Heal19_RS02860	ENOG4105E5Q	amino acid AbC transporter
Heal19_RS02865	ENOG4105CDA	abc transporter atp-binding protein
Heal19_RS02870	ENOG4108HW3	(ABC) transporter
Heal19_RS02875	ENOG4105CFH	Aspartokinase
Heal19_RS02895	ENOG4105BZQ	cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase
Heal19_RS02905	ENOG4105CEV	competence damage-inducible protein
Heal19_RS02910	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
Heal19_RS02915	ENOG4105E4Y	Endoribonuclease that initiates mRNA decay (By similarity)
Heal19_RS02920	ENOG4105D48	metallophosphoesterase
Heal19_RS02925	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
Heal19_RS02930	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
Heal19_RS02950	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
Heal19_RS02955	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
Heal19_RS02960	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
Heal19_RS02965	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
Heal19_RS02970	ENOG4105VIE	preprotein translocase, subunit YajC
Heal19_RS02975	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
Heal19_RS02980	ENOG4105SFS	phosphoesterase RecJ domain protein
Heal19_RS02985	ENOG4105C1J	atp-dependent rna helicase
Heal19_RS02990	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
Heal19_RS02995	ENOG4105VBH	UPF0297 protein
Heal19_RS03000	ENOG4108Z08	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
Heal19_RS03005	ENOG4105VPH	UPF0473 protein
Heal19_RS03015	ENOG4105C98	muts2 protein
Heal19_RS03020	ENOG4105K63	Thioredoxin
Heal19_RS03030	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
Heal19_RS03035	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
Heal19_RS03050	ENOG4105DMJ	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate (By similarity)
Heal19_RS03055	ENOG4105CH2	amidohydrolase
Heal19_RS03060	ENOG4105D8X	mechanosensitive ion channel
Heal19_RS03080	ENOG4105DC7	peptidase M24
Heal19_RS03085	ENOG4105ETE	Transcriptional regulator (LacI family
Heal19_RS03100	ENOG4105CDY	transcriptional regulatory protein
Heal19_RS03145	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
Heal19_RS03150	ENOG4105C85	amino acid
Heal19_RS03160	ENOG4107R8B	5'-nucleotidase
Heal19_RS03165	ENOG4105MMD	transcriptional regulator
Heal19_RS03170	ENOG4105D4U	had-superfamily hydrolase, subfamily iia
Heal19_RS03180	ENOG4105DQR	SNARE associated Golgi
Heal19_RS03330	ENOG4108RQ5	Beta-lactamase domain-containing protein
Heal19_RS03335	ENOG41090SU	Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress (By similarity)
Heal19_RS03340	ENOG4108SQ7	Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
Heal19_RS03350	ENOG4105DPN	Oligoendopeptidase f
Heal19_RS03365	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
Heal19_RS03370	ENOG4105EMS	pseudouridine synthase
Heal19_RS03375	ENOG4106N3A	copper homeostasis protein cutc
Heal19_RS03380	ENOG4105HHQ	6-phosphogluconolactonase (EC 3.1.1.31)
Heal19_RS03395	ENOG41082QR	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
Heal19_RS03405	ENOG4105CWM	branched-chain amino acid transport system II carrier protein
Heal19_RS03415	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
Heal19_RS03420	ENOG4105CNU	cell division protein FtsK
Heal19_RS03440	ENOG4108V6E	Cell division protein mraZ
Heal19_RS03445	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
Heal19_RS03455	ENOG4105CJN	penicillin-binding protein
Heal19_RS03460	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
Heal19_RS03465	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
Heal19_RS03470	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
Heal19_RS03475	ENOG4108W8M	Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex (By similarity)
Heal19_RS03490	ENOG4105VR5	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA (By similarity)
Heal19_RS03495	ENOG41067XK	integral membrane protein
Heal19_RS03510	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
Heal19_RS03515	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
Heal19_RS03520	ENOG4108YZ4	nudix hydrolase
Heal19_RS03530	ENOG4105DUF	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity)
Heal19_RS03535	ENOG4105C3J	Cysteine desulfurase
Heal19_RS03545	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
Heal19_RS03555	ENOG4107ZYR	domain protein
Heal19_RS03575	ENOG4105DKJ	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
Heal19_RS03585	ENOG4105C7H	Helicase, RecD TraA family
Heal19_RS03590	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
Heal19_RS03595	ENOG41069ER	domain protein
Heal19_RS03610	ENOG4105CN5	Metallo-Beta-Lactamase
Heal19_RS03615	ENOG4106EHS	UPF0356 protein
Heal19_RS03625	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
Heal19_RS03630	ENOG4107RUY	(E1 component), alpha subunit
Heal19_RS03650	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
Heal19_RS03655	ENOG4105WBI	UPF0223 protein
Heal19_RS03660	ENOG4105ECY	inositol monophosphatase
Heal19_RS03665	ENOG4105CI3	gtp-binding protein typa
Heal19_RS03690	ENOG4105CNI	cell division protein FtsW
Heal19_RS03695	ENOG4108JIJ	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second (By similarity)
Heal19_RS03700	ENOG4105WUC	UPF0298 protein
Heal19_RS03705	ENOG4106H78	methyltransferase
Heal19_RS03710	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
Heal19_RS03715	ENOG41063PX	domain protein
Heal19_RS03720	ENOG4105KQC	Competence protein
Heal19_RS03725	ENOG4108UK2	deaminase
Heal19_RS03730	ENOG4105EGY	DNA internalization-related competence protein ComEC Rec2
Heal19_RS03735	ENOG4105TQK	DNA polymerase iii, delta' subunit
Heal19_RS03740	ENOG4105KQV	Binds directly to 16S ribosomal RNA (By similarity)
Heal19_RS03745	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
Heal19_RS03750	ENOG4105C6X	Major Facilitator
Heal19_RS03755	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
Heal19_RS03770	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
Heal19_RS03775	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
Heal19_RS03780	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
Heal19_RS03785	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
Heal19_RS03805	ENOG4105EAD	ABC transporter
Heal19_RS03810	ENOG4105CDA	abc transporter atp-binding protein
Heal19_RS03815	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
Heal19_RS03825	ENOG4108QV3	biosynthesis protein
Heal19_RS03835	ENOG4108IAJ	Nad-dependent epimerase dehydratase
Heal19_RS03845	ENOG4107QPH	glycogen) synthase
Heal19_RS03860	ENOG4108RYC	glycosyltransferase
Heal19_RS03870	ENOG41070EG	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity)
Heal19_RS03875	ENOG4105DM4	PTS System
Heal19_RS03880	ENOG4105DE4	1-phosphofructokinase
Heal19_RS03885	ENOG4105E98	transcriptional regulator DeoR family
Heal19_RS03890	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
Heal19_RS03900	ENOG4105IES	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
Heal19_RS03905	ENOG4108IXY	short-chain dehydrogenase reductase
Heal19_RS03910	ENOG41067VP	Protein of unknown function (DUF1049)
Heal19_RS03915	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
Heal19_RS03920	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
Heal19_RS03935	ENOG4105K8R	UPF0145 protein
Heal19_RS03970	ENOG4108KGH	TRANSCRIPTIONal
Heal19_RS03980	ENOG4105CKK	Glycosyl transferase, family 2
Heal19_RS03995	ENOG4105F99	Hydroxymethylglutaryl-CoA synthase
Heal19_RS04010	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
Heal19_RS04015	ENOG4105VPS	UPF0291 protein
Heal19_RS04020	ENOG4105VXM	UPF0154 protein
Heal19_RS04025	ENOG4105F6E	Acyl-transferase
Heal19_RS04030	ENOG41060K3	Methyltransferase
Heal19_RS04035	ENOG4105VC4	domain protein
Heal19_RS04040	ENOG4105C5I	Dehydrogenase
Heal19_RS04050	ENOG4105CE9	30S ribosomal protein S2
Heal19_RS04055	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
Heal19_RS04060	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
Heal19_RS04065	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
Heal19_RS04070	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
Heal19_RS04075	ENOG4105KNE	Phosphatidate cytidylyltransferase
Heal19_RS04080	ENOG4105DZP	Membrane-associated zinc metalloprotease
Heal19_RS04085	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
Heal19_RS04090	ENOG4105DE5	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity)
Heal19_RS04095	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
Heal19_RS04100	ENOG4105CHV	Transcription elongation factor NusA
Heal19_RS04105	ENOG4105VZN	Nucleic-acid-binding protein implicated in transcription termination
Heal19_RS04115	ENOG4107EEM	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
Heal19_RS04120	ENOG4105KG7	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
Heal19_RS04125	ENOG4105EMV	Major Facilitator
Heal19_RS04130	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
Heal19_RS04140	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
Heal19_RS04155	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
Heal19_RS04160	ENOG4105DTN	riboflavin biosynthesis protein ribF
Heal19_RS04165	ENOG4107FQX	Alpha-acetolactate decarboxylase
Heal19_RS04170	ENOG4105CI8	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons (By similarity)
Heal19_RS04175	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
Heal19_RS04180	ENOG4105CFG	Acts as a chaperone (By similarity)
Heal19_RS04185	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
Heal19_RS04195	ENOG4105FQP	Beta-lactamase
Heal19_RS04205	ENOG4108IQD	Involved in the biosynthesis of D-alanyl-lipoteichoic acid (LTA). Catalyzes an ATP-dependent two-step reaction where it forms a high energy D-alanyl AMP intermediate and transfers the alanyl residues from AMP to Dcp (By similarity)
Heal19_RS04210	ENOG4105CK0	Membrane bOund o-acyl transferase mboat family protein
Heal19_RS04215	ENOG4105X96	Involved in the biosynthesis of D-alanyl-lipoteichoic acid (LTA). Activated D-alanyl-Dcp donates its D-alanyl substituent to membrane-associated LTA (By similarity)
Heal19_RS04220	ENOG4108M4D	D-alanyl-lipoteichoic acid biosynthesis protein DltD
Heal19_RS04225	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
Heal19_RS04250	ENOG4108VX5	3-methyladenine DNA glycosylase
Heal19_RS04255	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
Heal19_RS04260	ENOG4107TVK	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
Heal19_RS04270	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
Heal19_RS04275	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
Heal19_RS04280	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
Heal19_RS04290	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
Heal19_RS04295	ENOG4105CUT	histidyl-tRNA synthetase
Heal19_RS04300	ENOG4105C9M	aspartyl-trna synthetase
Heal19_RS04305	ENOG4108HW8	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
Heal19_RS04310	ENOG4107AYK	membrAne
Heal19_RS04320	ENOG4105EFU	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin (By similarity)
Heal19_RS04325	ENOG4105CHR	reductase
Heal19_RS04330	ENOG4105CF9	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation (By similarity)
Heal19_RS04335	ENOG4105VCC	30S ribosomal protein S21
Heal19_RS04340	ENOG4105KTH	gatB Yqey
Heal19_RS04345	ENOG4105C9A	Phoh family
Heal19_RS04350	ENOG4105KGE	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
Heal19_RS04355	ENOG4107YR5	Diacylglycerol kinase
Heal19_RS04360	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
Heal19_RS04365	ENOG4108SAY	Involved in DNA repair and RecF pathway recombination (By similarity)
Heal19_RS04370	ENOG4108HMW	glycyl-tRNA synthetase, alpha subunit
Heal19_RS04375	ENOG4105C38	Glycyl-tRNA synthetase beta subunit
Heal19_RS04380	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
Heal19_RS04385	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
Heal19_RS04390	ENOG4105W8V	TRANSCRIPTIONAl REGULATOR GntR family
Heal19_RS04395	ENOG4105CZV	ABC transporter
Heal19_RS04415	ENOG4105CJ1	ABC, transporter
Heal19_RS04430	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
Heal19_RS04440	ENOG4108M15	ABC transporter
Heal19_RS04450	ENOG4105BZU	Histidine kinase
Heal19_RS04455	ENOG4108S01	response regulator
Heal19_RS04460	ENOG4107QMW	pyridine nucleotide-disulfide oxidoreductase
Heal19_RS04465	ENOG4105EE6	Alcohol dehydrogenase zinc-binding domain protein
Heal19_RS04470	ENOG4108W5M	transcriptional regulator
Heal19_RS04500	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
Heal19_RS04530	ENOG4105E98	transcriptional regulator DeoR family
Heal19_RS04535	ENOG4107QMW	pyridine nucleotide-disulfide oxidoreductase
Heal19_RS04540	ENOG4107PP3	Acetylornithine deacetylase
Heal19_RS04550	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
Heal19_RS04560	ENOG4105C59	p-type ATPase
Heal19_RS04580	ENOG41082F9	transcriptional regulator
Heal19_RS04620	ENOG4105EGD	dinuclear metal center protein, YbgI family
Heal19_RS04625	ENOG4105D42	Cleaves the N-terminal amino acid of tripeptides (By similarity)
Heal19_RS04630	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
Heal19_RS04640	ENOG4105C0B	DNA polymerase III (alpha subunit)
Heal19_RS04645	ENOG4105CTQ	phosphohexokinase
Heal19_RS04650	ENOG4105CA9	Pyruvate kinase
Heal19_RS04660	ENOG4105QNR	S1 RNA binding domain protein
Heal19_RS04665	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
Heal19_RS04675	ENOG4108KVX	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves (By similarity)
Heal19_RS04680	ENOG4105K8I	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity)
Heal19_RS04685	ENOG4105FE9	pseudouridine synthase
Heal19_RS04690	ENOG4108SAX	Membrane
Heal19_RS04700	ENOG4105C9U	ATP-dependent DNA helicase RecQ
Heal19_RS04710	ENOG4105CAT	Cytidine monophosphate kinase
Heal19_RS04715	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
Heal19_RS04720	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
Heal19_RS04730	ENOG41068YB	TPR repeat-containing protein
Heal19_RS04735	ENOG4108HCJ	Hydrolase
Heal19_RS04740	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
Heal19_RS04745	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
Heal19_RS04755	ENOG4105C5H	ABC transporter
Heal19_RS04760	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
Heal19_RS04765	ENOG4108YYV	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity)
Heal19_RS04770	ENOG4108RCR	degv family
Heal19_RS04775	ENOG41090WU	lipolytic protein G-D-S-L family
Heal19_RS04780	ENOG4105QZP	Uncharacterized protein conserved in bacteria (DUF2140)
Heal19_RS04785	ENOG4105VSD	UPF0346 protein
Heal19_RS04810	ENOG4107RSM	transcriptional regulator
Heal19_RS04820	ENOG4105C9W	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity (By similarity)
Heal19_RS04825	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
Heal19_RS04830	ENOG4105C79	DNA protecting protein DprA
Heal19_RS04835	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
Heal19_RS04840	ENOG4107QXI	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs (By similarity)
Heal19_RS04845	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
Heal19_RS04850	ENOG4108R5P	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity)
Heal19_RS04855	ENOG4105C4N	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity)
Heal19_RS04865	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
Heal19_RS04870	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
Heal19_RS04880	ENOG4105DND	Transcriptional regulator
Heal19_RS04885	ENOG4105E2M	Manganese-dependent inorganic pyrophosphatase
Heal19_RS04890	ENOG4105E0X	reductase
Heal19_RS04895	ENOG4108HW8	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
Heal19_RS04930	ENOG4105K56	Transcriptional regulator
Heal19_RS04945	ENOG4107RZX	Teichoic acid biosynthesis protein
Heal19_RS04955	ENOG4108QHG	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity)
Heal19_RS04980	ENOG4105C85	amino acid
Heal19_RS05035	ENOG4105EPR	degv family
Heal19_RS05050	ENOG4108TU7	Inherit from COG: (ABC) transporter
Heal19_RS05055	ENOG4105CJ1	ABC, transporter
Heal19_RS05080	ENOG4108ZMX	Domain of unknown function (DU1801)
Heal19_RS05095	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
Heal19_RS05100	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
Heal19_RS05105	ENOG4108UK1	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant (By similarity)
Heal19_RS05110	ENOG4105C34	Pseudouridine synthase
Heal19_RS05115	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
Heal19_RS05120	ENOG4105CKU	formyltetrahydrofolate synthetase
Heal19_RS05135	ENOG4107VFR	oxidoreductase
Heal19_RS05165	ENOG4105EBE	Peptidase U61, LD-carboxypeptidase A
Heal19_RS05185	ENOG4105K64	Glycosyl transferase, family 2
Heal19_RS05195	ENOG4108MXZ	Esterase
Heal19_RS05210	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
Heal19_RS05220	ENOG4105XWG	Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation (By similarity)
Heal19_RS05225	ENOG4108UKS	UPF0398 protein
Heal19_RS05230	ENOG4108UI2	Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation (By similarity)
Heal19_RS05240	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
Heal19_RS05245	ENOG4107QKW	extracellular solute-binding protein family 1
Heal19_RS05250	ENOG4105D38	putrescine abc transporter
Heal19_RS05265	ENOG4108UMI	ABC transporter, permease
Heal19_RS05270	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
Heal19_RS05280	ENOG4105C5S	asparaginyl-tRNA synthetase
Heal19_RS05295	ENOG4105DVT	helicase
Heal19_RS05315	ENOG4106UJV	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP) (By similarity)
Heal19_RS05320	ENOG4105ENN	converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity)
Heal19_RS05340	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
Heal19_RS05345	ENOG4108KP7	hydrolase
Heal19_RS05350	ENOG4105CUB	amino acid
Heal19_RS05355	ENOG4108JPW	Aminotransferase
Heal19_RS05385	ENOG41069HH	4-oxalocrotonate tautomerase
Heal19_RS05390	ENOG4105DZW	Dipeptidase
Heal19_RS05400	ENOG4106EMP	CsbD-like
Heal19_RS05405	ENOG4107BMA	Transglycosylase associated protein
Heal19_RS05415	ENOG4105CBD	Diacylglycerol kinase
Heal19_RS05420	ENOG4105KAF	membrAne
Heal19_RS05430	ENOG4105KAV	tspo and mbr like protein
Heal19_RS05445	ENOG4108M1A	Chitin-binding protein
Heal19_RS05485	ENOG4105C57	major facilitator superfamily
Heal19_RS05495	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
Heal19_RS05500	ENOG4108S4H	thioesterase Superfamily protein
Heal19_RS05505	ENOG4105DUM	transcriptional regulator, lysR family
Heal19_RS05510	ENOG4108UQV	Membrane
Heal19_RS05520	ENOG4105CSJ	Enoyl- acyl-carrier-protein reductase NADH
Heal19_RS05535	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
Heal19_RS05540	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
Heal19_RS05550	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
Heal19_RS05555	ENOG4105CHR	reductase
Heal19_RS05560	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
Heal19_RS05565	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
Heal19_RS05570	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
Heal19_RS05575	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
Heal19_RS05585	ENOG4105E1F	short-chain dehydrogenase reductase
Heal19_RS05595	ENOG4105CPQ	Dehydrogenase
Heal19_RS05625	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
Heal19_RS05630	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
Heal19_RS05635	ENOG4108ZGB	N-(5'-phosphoribosyl)anthranilate isomerase
Heal19_RS05640	ENOG4105DK0	Indole-3-glycerol phosphate synthase
Heal19_RS05645	ENOG4108I0Q	anthranilate phosphoribosyltransferase
Heal19_RS05650	ENOG4105DDQ	anthranilate synthase
Heal19_RS05685	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
Heal19_RS05690	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
Heal19_RS05695	ENOG4107Z8R	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
Heal19_RS05700	ENOG4105VB6	UPF0109 protein
Heal19_RS05705	ENOG4105K5M	30s ribosomal protein S16
Heal19_RS05710	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
Heal19_RS05715	ENOG4105VBN	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein (By similarity)
Heal19_RS05720	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
Heal19_RS05725	ENOG4105CDB	Required for chromosome condensation and partitioning (By similarity)
Heal19_RS05730	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
Heal19_RS05735	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
Heal19_RS05740	ENOG4105C6B	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (By similarity)
Heal19_RS05745	ENOG4105CB5	ATP-dependent DNA helicase recG
Heal19_RS05750	ENOG4105DP4	dak2 domain fusion protein ylov
Heal19_RS05755	ENOG4108ZAA	Alkaline-shock protein
Heal19_RS05760	ENOG4105VB9	50S ribosomal protein l28
Heal19_RS05765	ENOG4105FJ0	thiamine
Heal19_RS05770	ENOG4105DJV	ribulose-phosphate 3-epimerase
Heal19_RS05775	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
Heal19_RS05780	ENOG4105D9P	serine threonine protein kinase
Heal19_RS05785	ENOG4108ZF3	Phosphatase
Heal19_RS05790	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
Heal19_RS05795	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
Heal19_RS05800	ENOG4105C25	Primosomal protein n'
Heal19_RS05805	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
Heal19_RS05810	ENOG4105ZAD	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
Heal19_RS05815	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
Heal19_RS05825	ENOG4105R40	Glycine betaine carnitine choline
Heal19_RS05830	ENOG4108HQR	Glycine betaine
Heal19_RS05845	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
Heal19_RS05850	ENOG4105XBY	Regulates arginine biosynthesis genes (By similarity)
Heal19_RS05855	ENOG4105DX0	Hemolysin A
Heal19_RS05860	ENOG4105CTB	Polyprenyl synthetase
Heal19_RS05865	ENOG41067QG	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
Heal19_RS05870	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
Heal19_RS05875	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
Heal19_RS05880	ENOG4105M7K	Involved in the transcription termination process (By similarity)
Heal19_RS05885	ENOG4108ZSR	alkaline shock protein
Heal19_RS05890	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
Heal19_RS05895	ENOG4105DC7	peptidase M24
Heal19_RS05900	ENOG4105K46	50S ribosomal protein l27
Heal19_RS05910	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
Heal19_RS05960	ENOG4105KV4	Transcriptional regulator
Heal19_RS05965	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
Heal19_RS05970	ENOG4108QXE	glycerophosphoryl diester phosphodiesterase
Heal19_RS05990	ENOG4105DKQ	ROK family
Heal19_RS06000	ENOG4107ZXI	Rhomboid family
Heal19_RS06005	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
Heal19_RS06010	ENOG4105WDJ	50S ribosomal protein L33
Heal19_RS06015	ENOG4107RF6	penicillin-binding protein
Heal19_RS06025	ENOG4105W8X	HesB YadR YfhF-family protein
Heal19_RS06040	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
Heal19_RS06045	ENOG4105DBI	uridine monophosphokinase
Heal19_RS06055	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
Heal19_RS06060	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
Heal19_RS06075	ENOG4108RWN	rrna methyltransferase
Heal19_RS06080	ENOG410855V	Acylphosphatase
Heal19_RS06085	ENOG4107XQC	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins (By similarity)
Heal19_RS06100	ENOG4105EYH	Exonuclease
Heal19_RS06110	ENOG4105GR3	Histidine kinase
Heal19_RS06115	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
Heal19_RS06120	ENOG4105D1H	recombination factor protein RarA
Heal19_RS06125	ENOG4105C7Q	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity)
Heal19_RS06145	ENOG41067VY	50S ribosomal protein L32
Heal19_RS06155	ENOG4105CDE	UPF0348 protein
Heal19_RS06160	ENOG4105DXX	methyltransferase
Heal19_RS06170	ENOG4108WF2	Metal Dependent Phosphohydrolase
Heal19_RS06175	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
Heal19_RS06180	ENOG410812S	Rna-binding protein
Heal19_RS06200	ENOG4105CND	Glycosyl transferase, family 2
Heal19_RS06210	ENOG4105KVH	Transcriptional regulator
Heal19_RS06215	ENOG4105CIS	alcohol dehydrogenase
Heal19_RS06220	ENOG4105D1H	recombination factor protein RarA
Heal19_RS06230	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
Heal19_RS06235	ENOG4105VJV	50s ribosomal protein L35
Heal19_RS06240	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
Heal19_RS06245	ENOG4105C22	threonyL-tRNA synthetase
Heal19_RS06260	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
Heal19_RS06265	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
Heal19_RS06270	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
Heal19_RS06275	ENOG4105C2M	dna polymerase I
Heal19_RS06285	ENOG4105VMP	Transcriptional regulator
Heal19_RS06305	ENOG4105D0D	Nitrate reductase 2, gamma subunit
Heal19_RS06315	ENOG4108IUE	nitrate reductase beta subunit
Heal19_RS06325	ENOG4105D06	uba thif-type nad fad binding protein
Heal19_RS06330	ENOG4105EPU	Molybdenum cofactor synthesis domain protein
Heal19_RS06335	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
Heal19_RS06340	ENOG4105FNP	Molybdopterin-guanine dinucleotide biosynthesis protein b
Heal19_RS06345	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
Heal19_RS06370	ENOG4105WH1	Two component transcriptional regulator luxr family
Heal19_RS06395	ENOG4105VG1	fes assembly suf system protein
Heal19_RS06405	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
Heal19_RS06425	ENOG4105EHG	Permease protein
Heal19_RS06430	ENOG4105E0A	ABC, transporter
Heal19_RS06440	ENOG4105DIW	FeS assembly protein SUFB
Heal19_RS06445	ENOG4108UNV	SUF system FeS assembly protein, NifU family
Heal19_RS06450	ENOG4105C9B	Cysteine desulfurase
Heal19_RS06455	ENOG4105JRK	feS assembly protein SufD
Heal19_RS06480	ENOG4105DFU	Cell wall formation (By similarity)
Heal19_RS06490	ENOG4108VDD	TRNA binding domain protein
Heal19_RS06500	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
Heal19_RS06505	ENOG4108V15	phosphotransferase enzyme family
Heal19_RS06520	ENOG4105K59	histidine triad (HIT) protein
Heal19_RS06530	ENOG4107UUG	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity)
Heal19_RS06560	ENOG4107QMW	pyridine nucleotide-disulfide oxidoreductase
Heal19_RS06570	ENOG4105DS0	Transcriptional regulator, Crp Fnr family
Heal19_RS06585	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
Heal19_RS06590	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
Heal19_RS06595	ENOG4108R6K	riboflavin synthase, subunit alpha
Heal19_RS06625	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
Heal19_RS06680	ENOG4107EFR	Flavocytochrome c
Heal19_RS06690	ENOG4105C5Q	Transcriptional regulator
Heal19_RS06705	ENOG4105EQI	Metal Dependent Phosphohydrolase
Heal19_RS06710	ENOG4106D4I	domain protein
Heal19_RS06715	ENOG4107VRP	DNA repair exonuclease
Heal19_RS06720	ENOG4105WZB	UPF0342 protein
Heal19_RS06725	ENOG4105BZ4	penicillin-binding protein
Heal19_RS06730	ENOG4105XBY	Regulates arginine biosynthesis genes (By similarity)
Heal19_RS06735	ENOG4105CHM	Aminotransferase
Heal19_RS06745	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
Heal19_RS06755	ENOG4105S7A	ErfK ybiS ycfS ynhG family protein
Heal19_RS06770	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
Heal19_RS06780	ENOG4105C75	arginyL-tRNA synthetase
Heal19_RS06785	ENOG4107YB6	acetyltransferase, (GNAT) family
Heal19_RS06820	ENOG4105SFS	phosphoesterase RecJ domain protein
Heal19_RS06825	ENOG4108I67	Catalyzes the synthesis of activated sulfate (By similarity)
Heal19_RS06830	ENOG4107RIQ	Sulfate adenylate transferase
Heal19_RS06840	ENOG4107QYE	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity)
Heal19_RS06960	ENOG4108N9J	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
Heal19_RS07155	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
Heal19_RS07170	ENOG4105K56	Transcriptional regulator
Heal19_RS07190	ENOG4108WCX	response regulator
Heal19_RS07205	ENOG410667J	hydrolase
Heal19_RS07210	ENOG4108UZ3	Transporter
Heal19_RS07220	ENOG4105VUF	Transcriptional regulator
Heal19_RS07225	ENOG4108HW8	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
Heal19_RS07235	ENOG4105W1Y	Transcriptional regulator
Heal19_RS07245	ENOG4105D74	hydrolase
Heal19_RS07250	ENOG4105D29	Helix-turn-helix type 11 domain protein
Heal19_RS07275	ENOG4105ECB	domain protein
Heal19_RS07275	ENOG4105ECB	domain protein
Heal19_RS07280	ENOG4105M2E	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
Heal19_RS07285	ENOG4105ZMH	deoxynucleoside kinase
Heal19_RS07290	ENOG4108QXE	glycerophosphoryl diester phosphodiesterase
Heal19_RS07300	ENOG4105DRS	transport system, permease
Heal19_RS07305	ENOG4105E4X	binding-protein-dependent transport systems inner membrane Component
Heal19_RS07310	ENOG4108IJ9	(ABC) transporter
Heal19_RS07320	ENOG4107QSE	Dipeptidase
Heal19_RS07325	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
Heal19_RS07340	ENOG4105C8T	Leucyl-tRNA synthetase
Heal19_RS07380	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
Heal19_RS07385	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
Heal19_RS07395	ENOG4105Q84	sucrose synthase
Heal19_RS07400	ENOG4107QK5	Homocysteine s-methyltransferase
Heal19_RS07405	ENOG4108IQI	permease
Heal19_RS07410	ENOG4107TTW	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
Heal19_RS07415	ENOG4105C56	H( )-stimulated, divalent metal cation uptake system (By similarity)
Heal19_RS07420	ENOG4108R1E	Serine threonine protein phosphatase 1
Heal19_RS07440	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
Heal19_RS07530	ENOG4105E0M	Sulfatase
Heal19_RS07535	ENOG4107IN1	Protein of unknown function (DUF1797)
Heal19_RS07540	ENOG4105CHM	Aminotransferase
Heal19_RS07555	ENOG4105W2C	Glycosyl transferase
Heal19_RS07560	ENOG4105BZF	Glycosyl transferase (Group 1
Heal19_RS07565	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
Heal19_RS07570	ENOG4105KRI	phosphocarrier protein (HPr
Heal19_RS07580	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
Heal19_RS07595	ENOG4108JQ7	(ABC) transporter
Heal19_RS07605	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
Heal19_RS07610	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
Heal19_RS07650	ENOG4105DC8	reductase
Heal19_RS07660	ENOG4105CMG	Carbohydrate kinase
Heal19_RS07665	ENOG4105C6Z	Gluconate
Heal19_RS07670	ENOG4107ZIC	Glycerol-3-phosphate cytidylyltransferase
Heal19_RS07675	ENOG4105C02	permease
Heal19_RS07685	ENOG4108A04	Beta-lactamase
Heal19_RS07700	ENOG4105K4H	Nlp p60 protein
Heal19_RS07705	ENOG4105EVI	UPF0374 protein
Heal19_RS07710	ENOG410902V	Modulates RecA activity (By similarity)
Heal19_RS07760	ENOG4108KMV	Glycosyl transferase (Group 1
Heal19_RS07775	ENOG4105C39	capsular polysaccharide phosphotransferase
Heal19_RS07780	ENOG4107RA4	Glycosyl transferase (Group 1
Heal19_RS07795	ENOG4108RB3	Capsular polysaccharide biosynthesis protein
Heal19_RS07800	ENOG4107YJ4	chain length determinant protein
Heal19_RS07815	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
Heal19_RS07840	ENOG4105K64	Glycosyl transferase, family 2
Heal19_RS07845	ENOG4107XU6	Glycosyl transferase (Group 1
Heal19_RS07880	ENOG4105D5D	udp-galactopyranose mutase
Heal19_RS07890	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
Heal19_RS07900	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
Heal19_RS07910	ENOG4107R37	Glutamate dehydrogenase
Heal19_RS07935	ENOG4105CK1	PTS System
Heal19_RS07950	ENOG4105FDU	atp-dependent rna helicase
Heal19_RS07955	ENOG4105EE0	oxidoreductase
Heal19_RS07960	ENOG4105VEQ	Cold shock protein
Heal19_RS07975	ENOG4106KNT	transcriptional regulator
Heal19_RS07985	ENOG4105CK1	PTS System
Heal19_RS08000	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
Heal19_RS08005	ENOG4105CBD	Diacylglycerol kinase
Heal19_RS08010	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
Heal19_RS08015	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
Heal19_RS08020	ENOG4105VB5	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
Heal19_RS08030	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
Heal19_RS08035	ENOG4105C4R	Atp-dependent dna helicase
Heal19_RS08040	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
Heal19_RS08045	ENOG4108U5N	UPF0316 protein
Heal19_RS08050	ENOG4108UPS	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis (By similarity)
Heal19_RS08055	ENOG4108ZW7	flagellar rod assembly protein muramidase flgj
Heal19_RS08085	ENOG4108JJ8	(ABC) transporter
Heal19_RS08090	ENOG4108JJ9	ABC, transporter
Heal19_RS08095	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
Heal19_RS08100	ENOG4105C4M	(Ubiquinol oxidase) subunit I
Heal19_RS08120	ENOG4105CUB	amino acid
Heal19_RS08130	ENOG4105C6K	Malic enzyme
Heal19_RS08135	ENOG4107ZGM	malolactic fermentation system
Heal19_RS08140	ENOG4105CMU	LysR family (Transcriptional regulator
Heal19_RS08155	ENOG4105C9Q	fumarate hydratase class II
Heal19_RS08170	ENOG4105F9F	transposase
Heal19_RS08185	ENOG4105XGS	Covalent carrier of the coenzyme of citrate lyase (By similarity)
Heal19_RS08205	ENOG4107QPK	)-transporter
Heal19_RS08210	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
Heal19_RS08220	ENOG4105DSE	periplasmic solute binding protein
Heal19_RS08225	ENOG4105CC5	ABC transporter
Heal19_RS08230	ENOG4105DIK	(ABC) transporter
Heal19_RS08235	ENOG4108K6F	triphosphoribosyl-dephospho-CoA synthase
Heal19_RS08240	ENOG4105ID8	Transcriptional regulator, ARAC family
Heal19_RS08250	ENOG4107GFK	fumarate
Heal19_RS08255	ENOG4105VG1	fes assembly suf system protein
Heal19_RS08260	ENOG4107QPK	)-transporter
Heal19_RS08265	ENOG4105D49	3-dehydroquinate synthase
Heal19_RS08270	ENOG4108JPM	phospho-2-dehydro-3-deoxyheptonate aldolase
Heal19_RS08275	ENOG4105E2X	shikimate dehydrogenase
Heal19_RS08280	ENOG4105CV1	Transketolase (EC 2.2.1.1)
Heal19_RS08300	ENOG4108UJD	30S ribosomal protein S9
Heal19_RS08305	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
Heal19_RS08310	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
Heal19_RS08320	ENOG4108JJB	ABC transporter
Heal19_RS08325	ENOG4108JJB	ABC transporter
Heal19_RS08335	ENOG41088B0	Major membrane immunogen
Heal19_RS08360	ENOG4108ZT0	50S ribosomal protein l17
Heal19_RS08365	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
Heal19_RS08370	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
Heal19_RS08375	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
Heal19_RS08380	ENOG41067V7	50S ribosomal protein L36
Heal19_RS08385	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
Heal19_RS08390	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
Heal19_RS08395	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
Heal19_RS08400	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
Heal19_RS08405	ENOG41084KY	50S ribosomal protein L30
Heal19_RS08410	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
Heal19_RS08415	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
Heal19_RS08420	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
Heal19_RS08425	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
Heal19_RS08430	ENOG41082QR	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
Heal19_RS08435	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
Heal19_RS08440	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
Heal19_RS08445	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
Heal19_RS08450	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
Heal19_RS08455	ENOG41082SA	50s ribosomal protein l29
Heal19_RS08460	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
Heal19_RS08465	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
Heal19_RS08470	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
Heal19_RS08475	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
Heal19_RS08480	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
Heal19_RS08485	ENOG41080UE	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
Heal19_RS08490	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
Heal19_RS08495	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
Heal19_RS08500	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
Heal19_RS08505	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
Heal19_RS08510	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
Heal19_RS08515	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
Heal19_RS08525	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
Heal19_RS08530	ENOG4108IIJ	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
Heal19_RS08535	ENOG41062JF	Transcriptional regulator
Heal19_RS08540	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
Heal19_RS08545	ENOG4105KEX	transcriptional regulator, ctsr
Heal19_RS08585	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
Heal19_RS08590	ENOG4105ZMH	deoxynucleoside kinase
Heal19_RS08600	ENOG4108IQI	permease
Heal19_RS08610	ENOG41062ES	Transcriptional regulator
Heal19_RS08630	ENOG4108KGH	TRANSCRIPTIONal
Heal19_RS08640	ENOG4105DWK	Membrane
Heal19_RS08645	ENOG4105VEQ	Cold shock protein
Heal19_RS08695	ENOG4105CAQ	asparagine synthetase
Heal19_RS08705	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
Heal19_RS08755	ENOG41082BM	Transcriptional regulator, arsr family
Heal19_RS08760	ENOG4105EMS	pseudouridine synthase
Heal19_RS08765	ENOG4105C9U	ATP-dependent DNA helicase RecQ
Heal19_RS08785	ENOG4105DZW	Dipeptidase
Heal19_RS08790	ENOG4105CU9	asparagine synthetase A
Heal19_RS08800	ENOG4108V3G	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity)
Heal19_RS08810	ENOG4107EFR	Flavocytochrome c
Heal19_RS08815	ENOG4107RSM	transcriptional regulator
Heal19_RS08830	ENOG4105DBI	uridine monophosphokinase
Heal19_RS08875	ENOG4105DZR	Type I site-specific deoxyribonuclease
Heal19_RS08880	ENOG4105CD8	aminopeptidase N
Heal19_RS08910	ENOG4105VBF	alkaline shock protein
Heal19_RS08925	ENOG4107BMA	Transglycosylase associated protein
Heal19_RS08930	ENOG4105EXC	Acyl-transferase
Heal19_RS08945	ENOG4105FCW	Major Facilitator superfamily
Heal19_RS08950	ENOG4105KVH	Transcriptional regulator
Heal19_RS08965	ENOG4108IMY	Transcriptional regulator
Heal19_RS08975	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
Heal19_RS08980	ENOG4105CS9	pantothenic acid kinase
Heal19_RS08985	ENOG4105EA8	2-Nitropropane dioxygenase
Heal19_RS08995	ENOG4105EEM	helicase
Heal19_RS09000	ENOG4105DQR	SNARE associated Golgi
Heal19_RS09005	ENOG4105CS2	ec 3.2.1.21
Heal19_RS09010	ENOG4105C5Y	PTS System
Heal19_RS09015	ENOG4105CID	antiterminator
Heal19_RS09020	ENOG4105RHY	Pfam:UPF0157
Heal19_RS09030	ENOG4105DKJ	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
Heal19_RS09045	ENOG4105KPY	Small multidrug resistance protein
Heal19_RS09055	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
Heal19_RS09085	ENOG4105K56	Transcriptional regulator
Heal19_RS09090	ENOG4107R7I	amino acid
Heal19_RS09095	ENOG410901P	UPF0249 protein
Heal19_RS09100	ENOG4105C5Y	PTS System
Heal19_RS09110	ENOG4105CI1	PTS System
Heal19_RS09115	ENOG4105DRP	amino acid AbC transporter
Heal19_RS09120	ENOG4105EAD	ABC transporter
Heal19_RS09125	ENOG4105CT1	(ABC) transporter
Heal19_RS09140	ENOG4105C5I	Dehydrogenase
Heal19_RS09145	ENOG4105CHM	Aminotransferase
Heal19_RS09150	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
Heal19_RS09165	ENOG4105G5W	regulator Fur family
Heal19_RS09170	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
Heal19_RS09180	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
Heal19_RS09195	ENOG4105CUB	amino acid
Heal19_RS09210	ENOG4105GYP	Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline (By similarity)
Heal19_RS09215	ENOG4105EXC	Acyl-transferase
Heal19_RS09225	ENOG4107T66	Releases the N-terminal proline from various substrates (By similarity)
Heal19_RS09230	ENOG4105C7K	acetolactate synthase
Heal19_RS09235	ENOG4105DTN	riboflavin biosynthesis protein ribF
Heal19_RS09240	ENOG4105C7K	acetolactate synthase
Heal19_RS09245	ENOG4105C7N	Xanthine uracil vitamin C permease
Heal19_RS09260	ENOG4105KPE	licD family
Heal19_RS09270	ENOG4105CUU	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity)
Heal19_RS09275	ENOG4105D49	3-dehydroquinate synthase
Heal19_RS09280	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
Heal19_RS09295	ENOG41090SU	Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress (By similarity)
Heal19_RS09310	ENOG4108HMR	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
Heal19_RS09325	ENOG4108DBC	nitroreductase
Heal19_RS09340	ENOG4105ENN	converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity)
Heal19_RS09350	ENOG4108HCJ	Hydrolase
Heal19_RS09360	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
Heal19_RS09365	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
Heal19_RS09390	ENOG4107SUZ	Sodium/hydrogen exchanger family
Heal19_RS09395	ENOG4105D4A	Cell wall formation (By similarity)
Heal19_RS09400	ENOG4105EP9	oxidoreductase
Heal19_RS09405	ENOG4105CGK	Exodeoxyribonuclease III
Heal19_RS09410	ENOG4105DE5	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity)
Heal19_RS09420	ENOG4105K8N	protein family UPF0079, ATPase
Heal19_RS09425	ENOG4108IJ2	phosphate acetyltransferase
Heal19_RS09430	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
Heal19_RS09445	ENOG4105CDA	abc transporter atp-binding protein
Heal19_RS09450	ENOG4105E5Q	amino acid AbC transporter
Heal19_RS09460	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
Heal19_RS09465	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
Heal19_RS09475	ENOG4105XZU	Preprotein translocase, subunit SecG
Heal19_RS09480	ENOG4105CMQ	Chloride channel
Heal19_RS09490	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
Heal19_RS09495	ENOG4105CP7	Triose-phosphate isomerase
Heal19_RS09500	ENOG4105BZA	Phosphoglycerate kinase
Heal19_RS09505	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
Heal19_RS09515	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
Heal19_RS09525	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
Heal19_RS09530	ENOG4105C5I	Dehydrogenase
Heal19_RS09535	ENOG4107QSI	ABC, transporter
Heal19_RS09540	ENOG4105CIE	May be required for sporulation (By similarity)
Heal19_RS09550	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
Heal19_RS09560	ENOG4105CH7	arginosuccinase
Heal19_RS09565	ENOG4105CDH	Citrulline--aspartate ligase
Heal19_RS09570	ENOG4106762	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD) (By similarity)
Heal19_RS09575	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
Heal19_RS09580	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
Heal19_RS09600	ENOG4107QMW	pyridine nucleotide-disulfide oxidoreductase
Heal19_RS09620	ENOG4105H67	Protein of unknown function (DUF421)
Heal19_RS09625	ENOG4105C3M	thioredoxin reductase
Heal19_RS09630	ENOG4107QMW	pyridine nucleotide-disulfide oxidoreductase
Heal19_RS09640	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
Heal19_RS09645	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
Heal19_RS09650	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
Heal19_RS09655	ENOG4105D1C	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion (By similarity)
Heal19_RS09660	ENOG41086DT	Membrane protein of unknown function
Heal19_RS09670	ENOG4108UTW	Plays a role in the regulation of phosphate uptake
Heal19_RS09675	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
Heal19_RS09680	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
Heal19_RS09685	ENOG4105E2Z	phosphate ABC transporter (Permease
Heal19_RS09695	ENOG4105CVA	phosphate
Heal19_RS09700	ENOG4105BZU	Histidine kinase
Heal19_RS09705	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
Heal19_RS09720	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
Heal19_RS09740	ENOG4108ZK7	protein family UPF0029, Impact, N-terminal protein
Heal19_RS09745	ENOG4105CVA	phosphate
Heal19_RS09750	ENOG4105ESV	Glycosyl transferase, family 4
Heal19_RS09755	ENOG4105C0X	amino acid
Heal19_RS09760	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
Heal19_RS09765	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
Heal19_RS09775	ENOG4105FF6	Modulates transcription in response to changes in cellular NADH NAD( ) redox state (By similarity)
Heal19_RS09780	ENOG4105C5H	ABC transporter
Heal19_RS09785	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
Heal19_RS09790	ENOG410801F	ribosomal-protein-alanine acetyltransferase
Heal19_RS09795	ENOG41080E2	ribosomal-protein-alanine acetyltransferase
Heal19_RS09800	ENOG41072GX	Peptidase M22 Glycoprotease
Heal19_RS09810	ENOG4105D5T	phosphonate abc transporter
Heal19_RS09820	ENOG4105S7S	phosphonate abc transporter
Heal19_RS09825	ENOG4108KAZ	Involved in phosphonate degradation (By similarity)
Heal19_RS09830	ENOG4107STF	Involved in phosphonate degradation (By similarity)
Heal19_RS09835	ENOG4105CMR	udp-glucose 4-epimerase
Heal19_RS09850	ENOG41063V3	Involved in initiation control of chromosome replication (By similarity)
Heal19_RS09855	ENOG4105FA2	dna polymerase iii
Heal19_RS09860	ENOG4105X0R	protein from nitrogen regulatory protein P-II
Heal19_RS09865	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
Heal19_RS09875	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
Heal19_RS09880	ENOG410816I	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
Heal19_RS09885	ENOG4105C6E	dna polymerase iii
Heal19_RS09900	ENOG4107Y49	methyltransferase
Heal19_RS09905	ENOG41067VN	Glutaredoxin
Heal19_RS09910	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
Heal19_RS09920	ENOG4108URH	decarboxylase
Heal19_RS09940	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
Heal19_RS09945	ENOG4108VZM	50s ribosomal protein L10
Heal19_RS09950	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
Heal19_RS09955	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
Heal19_RS09965	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
Heal19_RS09975	ENOG4107FTN	50S ribosomal protein L33
Heal19_RS09990	ENOG4105C2N	RNA methyltransferase TrmH family group 3
Heal19_RS09995	ENOG4105KEB	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
Heal19_RS10000	ENOG4105C8N	cysteinyl-tRNA synthetase
Heal19_RS10005	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
Heal19_RS10010	ENOG4105CTP	PilT protein domain protein
Heal19_RS10020	ENOG4107Z0P	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity)
Heal19_RS10030	ENOG4105E66	phosphoriboisomerase A
Heal19_RS10035	ENOG4105CTZ	aminopeptidase c
Heal19_RS10045	ENOG4108K79	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
Heal19_RS10050	ENOG4108TVT	permease
Heal19_RS10060	ENOG4108KGH	TRANSCRIPTIONal
Heal19_RS10065	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
Heal19_RS10075	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
Heal19_RS10085	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
Heal19_RS10090	ENOG4105DAS	pts system
Heal19_RS10095	ENOG4105DAS	pts system
Heal19_RS10100	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
Heal19_RS10110	ENOG4105F3R	pts system mannose fructose sorbose family iid
Heal19_RS10115	ENOG4105ETZ	PTS System
Heal19_RS10135	ENOG4105D5I	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate (By similarity)
Heal19_RS10140	ENOG4105D6E	homoserine dehydrogenase
Heal19_RS10145	ENOG410906U	SprT-like
Heal19_RS10165	ENOG4107RA1	nh(3)-dependent nad( ) synthetase
Heal19_RS10170	ENOG4105DAP	Nicotinate phosphoribosyltransferase
Heal19_RS10190	ENOG4105II7	pyrroline-5-carboxylate reductase
Heal19_RS10195	ENOG4106Z1T	Nicotinamide Mononucleotide Transporter
Heal19_RS10240	ENOG4105DUX	Transporter
Heal19_RS10285	ENOG4105CRK	lysyL-tRNA synthetase
Heal19_RS10290	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
Heal19_RS10295	ENOG4105F4C	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity)
Heal19_RS10310	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
Heal19_RS10315	ENOG41060GV	RNA binding s1 domain protein
Heal19_RS10325	ENOG41082I2	s4 domain protein
Heal19_RS10335	ENOG4108JA2	transcriptioN-repair coupling factor
Heal19_RS10340	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
Heal19_RS10345	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
Heal19_RS10365	ENOG4105DBV	ornithine carbamoyltransferase
Heal19_RS10370	ENOG4105C8Y	Acetylornithine aminotransferase
Heal19_RS10375	ENOG4105CAS	nag kinase
Heal19_RS10380	ENOG4105C5V	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity)
Heal19_RS10385	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
Heal19_RS10390	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
Heal19_RS10400	ENOG4105DFH	Transport of potassium into the cell (By similarity)
Heal19_RS10405	ENOG4108YZM	Toxic component of a toxin-antitoxin (TA) module (By similarity)
Heal19_RS10410	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
Heal19_RS10415	ENOG41082V8	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (By similarity)
Heal19_RS10420	ENOG4105C1J	atp-dependent rna helicase
Heal19_RS10425	ENOG4107EES	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide the precursor of murein (By similarity)
Heal19_RS10435	ENOG4105D0M	Protease HtpX homolog
Heal19_RS10440	ENOG4108V0P	LemA family
Heal19_RS10445	ENOG4108Z6X	(sortase) family
Heal19_RS10455	ENOG41082DI	50s ribosomal protein l31
Heal19_RS10460	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
Heal19_RS10465	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
Heal19_RS10480	ENOG4105EJQ	L-serine dehydratase
Heal19_RS10490	ENOG4105C44	Serine transporter
Heal19_RS10495	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
Heal19_RS10500	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
Heal19_RS10505	ENOG4108Z1Y	Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling (By similarity)
Heal19_RS10515	ENOG4105JGI	Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes (By similarity)
Heal19_RS10520	ENOG4105DCI	Phosphohydrolase
Heal19_RS10540	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
Heal19_RS10550	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
Heal19_RS10555	ENOG4105DFT	pur operon repressor
Heal19_RS10560	ENOG4105CC5	ABC transporter
Heal19_RS10565	ENOG4105FDK	ABC transporter
Heal19_RS10575	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
Heal19_RS10580	ENOG4105W42	Veg protein
Heal19_RS10585	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
Heal19_RS10590	ENOG4105HVR	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step (By similarity)
Heal19_RS10595	ENOG4105F8V	Hydrolase, tatD family
Heal19_RS10600	ENOG4105C2C	drug resistance transporter, Bcr CflA
Heal19_RS10605	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
Heal19_RS10615	ENOG4105I3N	Conserved Protein
Heal19_RS10620	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
Heal19_RS10635	ENOG4105C9X	ppx gppa phosphatase
Heal19_RS10660	ENOG4105DKQ	ROK family
Heal19_RS10665	ENOG4105CS2	ec 3.2.1.21
Heal19_RS10670	ENOG4105CK1	PTS System
Heal19_RS10685	ENOG4105CK1	PTS System
Heal19_RS10690	ENOG4108S3Y	transcriptional regulator
Heal19_RS10695	ENOG4105C31	Tryptophanyl-tRNA synthetase
Heal19_RS10700	ENOG4105CQP	nitrilase cyanide hydratase and apolipoprotein n-acyltransferase
Heal19_RS10705	ENOG4105EEM	helicase
Heal19_RS10740	ENOG4108JJA	ABC, transporter
Heal19_RS10765	ENOG4108WCX	response regulator
Heal19_RS10785	ENOG4107R0E	Glycosyl transferase, family 2
Heal19_RS10825	ENOG4105CWM	branched-chain amino acid transport system II carrier protein
Heal19_RS10830	ENOG410667J	hydrolase
Heal19_RS10835	ENOG4108BRW	Activates expression of the rhaSR operon in response to L-rhamnose (By similarity)
Heal19_RS10840	ENOG4108HCJ	Hydrolase
Heal19_RS10850	ENOG4108UW5	maltose o-acetyltransferase
Heal19_RS10885	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
Heal19_RS10890	ENOG4105C6V	Glycerol-3-phosphate dehydrogenase
Heal19_RS10895	ENOG4108HMR	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
Heal19_RS10905	ENOG4108IJ8	ABC transporter
Heal19_RS10925	ENOG4105E1F	short-chain dehydrogenase reductase
Heal19_RS10930	ENOG4105DU0	nucleoside hydrolase
Heal19_RS10955	ENOG4105KIS	phospholipid-binding protein
Heal19_RS10960	ENOG4105KA3	membrAne
Heal19_RS10970	ENOG4105E66	phosphoriboisomerase A
Heal19_RS10990	ENOG4105BZU	Histidine kinase
Heal19_RS11010	ENOG4105EY8	ABC transporter
Heal19_RS11030	ENOG4108JZF	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
Heal19_RS11035	ENOG4108UMI	ABC transporter, permease
Heal19_RS11045	ENOG4105D01	(LipO)protein
Heal19_RS11055	ENOG41080Y5	BioY family
Heal19_RS11065	ENOG4105DZW	Dipeptidase
Heal19_RS11090	ENOG4105C0A	alcohol dehydrogenase
Heal19_RS11100	ENOG4105CZV	ABC transporter
Heal19_RS11105	ENOG410811P	TRANSCRIPTIONAl REGULATOR GntR family
Heal19_RS11135	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
Heal19_RS11150	ENOG4108HM4	ABC transporter
Heal19_RS11175	ENOG4105CEP	NADH dehydrogenase
Heal19_RS11180	ENOG4108U05	Transcriptional regulator
Heal19_RS11190	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
Heal19_RS11220	ENOG41068JE	domain protein
Heal19_RS11225	ENOG4106770	Is able to cleave peptidoglycan (By similarity)
Heal19_RS11245	ENOG4107WD8	ABC transporter, permease
Heal19_RS11255	ENOG4108R3E	Dna-3-methyladenine glycosylase i
Heal19_RS11260	ENOG4105EYF	MMPL domain protein
Heal19_RS11260	ENOG4105EYF	MMPL domain protein
Heal19_RS11280	ENOG4105CQB	FAD linked oxidase domain protein
Heal19_RS11285	ENOG4108KGH	TRANSCRIPTIONal
Heal19_RS11315	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
Heal19_RS11320	ENOG4105GR3	Histidine kinase
Heal19_RS11350	ENOG4105C56	H( )-stimulated, divalent metal cation uptake system (By similarity)
Heal19_RS11355	ENOG4105MKU	Transcriptional regulator
Heal19_RS11360	ENOG4108Z40	Transcriptional regulator
Heal19_RS11365	ENOG41062SP	
Heal19_RS11370	ENOG4108UMA	3-octaprenyl-4-hydroxybenzoate carboxy-lyase
Heal19_RS11375	ENOG4107SJB	teichoic acid biosynthesis
Heal19_RS11380	ENOG4107SJB	teichoic acid biosynthesis
Heal19_RS11385	ENOG4107SJB	teichoic acid biosynthesis
Heal19_RS11390	ENOG4107ZIC	Glycerol-3-phosphate cytidylyltransferase
Heal19_RS11400	ENOG4105C5Y	PTS System
Heal19_RS11405	ENOG4105C5Y	PTS System
Heal19_RS11410	ENOG4105CG3	alpha amylase, catalytic region
Heal19_RS11415	ENOG4107414	GntR family transcriptional regulator
Heal19_RS11435	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
Heal19_RS11440	ENOG4105C6T	cysteine synthase
Heal19_RS11445	ENOG4105C28	cystathionine
Heal19_RS11470	ENOG41069H0	dihydroorotase EC 3.5.2.3
Heal19_RS11485	ENOG4105CK1	PTS System
Heal19_RS11490	ENOG4105FDP	GntR family transcriptional regulator
Heal19_RS11495	ENOG4108YYH	Nadph-dependent fmn reductase
Heal19_RS11525	ENOG4105K63	Thioredoxin
Heal19_RS11535	ENOG4107SQ3	mannitol-1-phosphate 5-dehydrogenase
Heal19_RS11540	ENOG4105DTZ	bifunctional PTS system fructose-specific transporter subunit IIA HPr protein
Heal19_RS11550	ENOG4105CTS	PTS system mannitol-specific
Heal19_RS11555	ENOG4105DZW	Dipeptidase
Heal19_RS11560	ENOG4105CKA	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion (By similarity)
Heal19_RS11575	ENOG4105KP9	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
Heal19_RS11585	ENOG4108V06	Glutathione peroxidase
Heal19_RS11595	ENOG4108JJB	ABC transporter
Heal19_RS11615	ENOG4106A8V	Protein CrcB homolog
Heal19_RS11625	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
Heal19_RS11645	ENOG4105CPC	Aldo Keto reductase
Heal19_RS11650	ENOG4105CVJ	phosphoglycerate mutase
Heal19_RS11655	ENOG4107QM1	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
Heal19_RS11660	ENOG4108JQ1	Dehydrogenase
Heal19_RS11690	ENOG4105C5Q	Transcriptional regulator
Heal19_RS11700	ENOG4105DFD	Na H antiporter
Heal19_RS11715	ENOG4105ETE	Transcriptional regulator (LacI family
Heal19_RS11720	ENOG4108HKT	sucrose-6-phosphate hydrolase
Heal19_RS11725	ENOG4105C5Y	PTS System
Heal19_RS11730	ENOG4105EVU	fructokinase
Heal19_RS11750	ENOG4108IJ9	(ABC) transporter
Heal19_RS11755	ENOG4107S9Q	Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB (By similarity)
Heal19_RS11765	ENOG4105EG2	ABC transporter, permease
Heal19_RS11770	ENOG4105D56	permease protein
Heal19_RS11775	ENOG4107FKK	extracellular solute-binding protein family 1
Heal19_RS11785	ENOG4105FKQ	transcriptional regulator
Heal19_RS11795	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
Heal19_RS11800	ENOG4105VDH	Dihydroxyacetone kinase
Heal19_RS11805	ENOG4108UTZ	Dihydroxyacetone kinase
Heal19_RS11810	ENOG4105CMT	Dihydroxyacetone kinase
Heal19_RS11815	ENOG4105CMT	Dihydroxyacetone kinase
Heal19_RS11825	ENOG4105X71	Membrane
Heal19_RS11830	ENOG4105C10	Electron transfer flavoprotein
Heal19_RS11845	ENOG4105CIG	ABC transporter
Heal19_RS11850	ENOG4105EWI	Short-chain dehydrogenase reductase Sdr
Heal19_RS11875	ENOG4108TZY	GntR Family Transcriptional Regulator
Heal19_RS11885	ENOG4108V7D	UPF0397 protein
Heal19_RS11890	ENOG4108JJB	ABC transporter
Heal19_RS11895	ENOG4105EK6	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates (By similarity)
Heal19_RS11925	ENOG4107S5I	aldo keto reductase
Heal19_RS11935	ENOG4105DJ2	Major Facilitator Superfamily
Heal19_RS11975	ENOG41067S9	phage shock protein C, PspC
Heal19_RS11995	ENOG4105WKZ	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease (By similarity)
Heal19_RS12035	ENOG4108Z86	Glutamine amidotransferase
Heal19_RS12045	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
Heal19_RS12050	ENOG4105DWF	phosphomethylpyrimidine kinase
Heal19_RS12055	ENOG4105C4U	4-methyl-5-beta-hydroxyethylthiazole kinase
Heal19_RS12060	ENOG4105CIS	alcohol dehydrogenase
Heal19_RS12065	ENOG4105DVM	PP-loop domain protein
Heal19_RS12070	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
Heal19_RS12085	ENOG4105DTC	1-(5-phosphoribosyl)-5-amino-4-imidazole-carboxylate (air) carboxylase
Heal19_RS12090	ENOG4105QUH	Domain of unknown function (DUF2088)
Heal19_RS12095	ENOG4105TV1	Transcriptional regulator
Heal19_RS12100	ENOG4105CFT	Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import (By similarity)
Heal19_RS12105	ENOG41082M7	Cobalt transport protein
Heal19_RS12110	ENOG4108JJB	ABC transporter
Heal19_RS12145	ENOG4105D1Q	UPF0246 protein
Heal19_RS12150	ENOG4107RCM	Releases the N-terminal proline from various substrates (By similarity)
Heal19_RS12170	ENOG4105CIS	alcohol dehydrogenase
Heal19_RS12205	ENOG4107YCK	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity)
Heal19_RS12225	ENOG4105EFA	4-hydroxyphenylacetate
Heal19_RS12230	ENOG4105M2Z	protein tyrosine serine phosphatase
Heal19_RS12240	ENOG4107QHE	Choloylglycine hydrolase
Heal19_RS12245	ENOG4105EVE	HAD-superfamily hydrolase subfamily IA variant 3
Heal19_RS12250	ENOG4105G9B	Transcriptional regulator
Heal19_RS12255	ENOG4108TVJ	Nitroreductase
Heal19_RS12265	ENOG4105DTD	Dehydrogenase
Heal19_RS12270	ENOG4108UXE	Protein tyrosine phosphatase
Heal19_RS12285	ENOG4107QPK	)-transporter
Heal19_RS12290	ENOG4107EFR	Flavocytochrome c
Heal19_RS12315	ENOG4108RG0	uracil-dna glycosylase
Heal19_RS12320	ENOG4108HFV	
Heal19_RS12325	ENOG4107RGH	Aldehyde dehydrogenase
Heal19_RS12335	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
Heal19_RS12340	ENOG4105C0H	protease
Heal19_RS12345	ENOG4105Q2H	domain protein
Heal19_RS12360	ENOG4105BZU	Histidine kinase
Heal19_RS12365	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
Heal19_RS12380	ENOG4105VEQ	Cold shock protein
Heal19_RS12390	ENOG4105C71	hydrolase family 65, central catalytic
Heal19_RS12395	ENOG4107URF	beta-phospho-glucomutase
Heal19_RS12405	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
Heal19_RS12415	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
Heal19_RS12425	ENOG4105CNB	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
Heal19_RS12430	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
Heal19_RS12435	ENOG4108J59	Extracellular solute-binding protein, family 5
Heal19_RS12440	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
Heal19_RS12445	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
Heal19_RS12450	ENOG410605W	Major Facilitator
Heal19_RS12460	ENOG4105CDU	Replicative dna helicase
Heal19_RS12465	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
Heal19_RS12475	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
Heal19_RS12480	ENOG4108UUM	single-stranded DNA-binding protein
Heal19_RS12485	ENOG4108ZDX	Binds together with S18 to 16S ribosomal RNA (By similarity)
Heal19_RS12495	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
Heal19_RS12500	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
Heal19_RS12505	ENOG410848D	S4 domain protein YaaA
Heal19_RS12510	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
Heal19_RS12515	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
Heal19_RS12520	ENOG4105VG0	50S ribosomal protein l34
Heal19_RS12525	ENOG4105M7T	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
Heal19_RS12530	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
Heal19_RS12535	ENOG4107QSI	ABC, transporter
Heal19_RS12550	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
Heal19_RS12555	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
Heal19_RS12580	ENOG4105C3F	Signal peptidase i
Heal19_RS12610	ENOG4105PY6	Phenolic acid decarboxylase
Heal19_RS12615	ENOG4105U3E	Transcriptional regulator
Heal19_RS12625	ENOG4105C0A	alcohol dehydrogenase
Heal19_RS12630	ENOG4105ETE	Transcriptional regulator (LacI family
Heal19_RS12640	ENOG4105MRB	Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose (By similarity)
Heal19_RS12645	ENOG4105EV1	Ribose uptake protein RbsU
Heal19_RS12650	ENOG4105CHR	reductase
Heal19_RS12665	ENOG410787A	Pts system, glucitol sorbitol-specific
Heal19_RS12670	ENOG4105DZY	Pts system, glucitol sorbitol-specific
Heal19_RS12685	ENOG4108TZY	GntR Family Transcriptional Regulator
Heal19_RS12690	ENOG4105BZ1	(ABC) transporter
Heal19_RS12695	ENOG4105BZ1	(ABC) transporter
Heal19_RS12700	ENOG410874W	AraC family transcriptional regulator
Heal19_RS12715	ENOG4105C50	Binding-protein-dependent transport systems, inner membrane component
Heal19_RS12725	ENOG4105CG3	alpha amylase, catalytic region
Heal19_RS12735	ENOG4105C2F	Histidine kinase
Heal19_RS12740	ENOG4105EQD	regulatoR
Heal19_RS12750	ENOG4108IJ9	(ABC) transporter
Heal19_RS12760	ENOG4105FDP	GntR family transcriptional regulator
Heal19_RS12770	ENOG4105C8I	hydrolase, family 38
Heal19_RS12775	ENOG41066F8	ROK family
Heal19_RS12780	ENOG4105CS2	ec 3.2.1.21
Heal19_RS12785	ENOG4105CHR	reductase
Heal19_RS12790	ENOG4105EMD	TRANSCRIPTIONal
Heal19_RS12800	ENOG410787A	Pts system, glucitol sorbitol-specific
Heal19_RS12805	ENOG4105DZY	Pts system, glucitol sorbitol-specific
Heal19_RS12820	ENOG4105DU0	nucleoside hydrolase
Heal19_RS12825	ENOG4105CIS	alcohol dehydrogenase
Heal19_RS12830	ENOG41090KN	UPF0303 protein
Heal19_RS12835	ENOG4105CK5	oxidoreductase
Heal19_RS12840	ENOG4107QNK	)-transporter
Heal19_RS12845	ENOG4105CK5	oxidoreductase
Heal19_RS12850	ENOG4105CJK	Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol) (By similarity)
Heal19_RS12855	ENOG4105CK5	oxidoreductase
Heal19_RS12860	ENOG4105DRI	Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity)
Heal19_RS12865	ENOG4105C54	Major Facilitator superfamily
Heal19_RS12875	ENOG4105DT3	PTS system, galactitol-specific IIc component
Heal19_RS12890	ENOG4105E98	transcriptional regulator DeoR family
Heal19_RS12895	ENOG41075H3	AraC family transcriptional regulator
Heal19_RS12905	ENOG4105DET	Rhamnulokinase
Heal19_RS12910	ENOG4105M10	Involved in the anomeric conversion of L-rhamnose (By similarity)
Heal19_RS12915	ENOG4105DKG	l-rhamnose isomerase
Heal19_RS12920	ENOG4105C9J	Catalyzes the reversible cleavage of L-rhamnulose-1- phosphate to dihydroxyacetone phosphate (DHAP) and L-lactaldehyde (By similarity)
Heal19_RS12935	ENOG4105C7K	acetolactate synthase
Heal19_RS12940	ENOG4108Z40	Transcriptional regulator
Heal19_RS12945	ENOG4105C7K	acetolactate synthase
Heal19_RS12965	ENOG410695V	Essential for the production of a quorum sensing system signal molecule, the autoinducing peptide (AIP). This quorum sensing system is responsible for the regulation of the expression of virulence factor genes. Involved in the proteolytic processing of AgrD, the precursor of AIP (By similarity)
Heal19_RS12985	ENOG41090SU	Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress (By similarity)
Heal19_RS12995	ENOG4107BMA	Transglycosylase associated protein
Heal19_RS13015	ENOG4105C9S	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P) (By similarity)
Heal19_RS13020	ENOG4105CMD	Transcriptional regulator, GntR family
Heal19_RS13025	ENOG4107QNK	)-transporter
Heal19_RS13040	ENOG4105CAC	Catalyzes the conversion of L-arabinose to L-ribulose (By similarity)
Heal19_RS13045	ENOG4108UW5	maltose o-acetyltransferase
Heal19_RS13055	ENOG4107QRI	Phosphoketolase
Heal19_RS13060	ENOG4105E98	transcriptional regulator DeoR family
Heal19_RS13070	ENOG4105K18	The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane (By similarity)
Heal19_RS13075	ENOG4105DT3	PTS system, galactitol-specific IIc component
Heal19_RS13110	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
Heal19_RS13125	ENOG4107QHE	Choloylglycine hydrolase
Heal19_RS13145	ENOG4105ETE	Transcriptional regulator (LacI family
Heal19_RS13160	ENOG4105C5Y	PTS System
Heal19_RS13165	ENOG4105CS2	ec 3.2.1.21
Heal19_RS13170	ENOG4105CS2	ec 3.2.1.21
Heal19_RS13175	ENOG4105CID	antiterminator
Heal19_RS13185	ENOG4105CS2	ec 3.2.1.21
Heal19_RS13195	ENOG4105RD7	BadF BadG BcrA BcrD
Heal19_RS13200	ENOG4105E15	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
Heal19_RS13205	ENOG4105CK1	PTS System
Heal19_RS13215	ENOG41088PD	hydrolase
Heal19_RS13225	ENOG4105EMV	Major Facilitator
Heal19_RS13230	ENOG4105DUM	transcriptional regulator, lysR family
Heal19_RS13260	ENOG4105C5Q	Transcriptional regulator
Heal19_RS13265	ENOG4105E2X	shikimate dehydrogenase
Heal19_RS13270	ENOG4105FF2	Type I DHQase
Heal19_RS13290	ENOG4105CPC	Aldo Keto reductase
Heal19_RS13295	ENOG4105CQ4	Transcriptional regulator
Heal19_RS13300	ENOG4105ENN	converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity)
Heal19_RS13305	ENOG4107RBJ	symporter
Heal19_RS13310	ENOG4105DME	alpha-galactosidase
Heal19_RS13325	ENOG4105CRD	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity)
Heal19_RS13330	ENOG4105CMR	udp-glucose 4-epimerase
Heal19_RS13335	ENOG4105CKN	UDP-glucose-hexose-1-phosphate uridylyltransferase
Heal19_RS13340	ENOG4105CQ4	Transcriptional regulator
Heal19_RS13345	ENOG4105W08	virulence gene repressor rsal
Heal19_RS13350	ENOG4105MZU	cell filamentation protein
Heal19_RS13370	ENOG4107UWP	Major facilitator superfamily MFS_1
Heal19_RS13390	ENOG4107RBJ	symporter
Heal19_RS13395	ENOG4105CWM	branched-chain amino acid transport system II carrier protein
Heal19_RS13405	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
Heal19_RS13450	ENOG4107QMW	pyridine nucleotide-disulfide oxidoreductase
Heal19_RS13465	ENOG4105C9K	Endothelin-converting enzyme 1
Heal19_RS13470	ENOG4105IJJ	transcriptional regulator, crp fnr family
Heal19_RS13495	ENOG4105K63	Thioredoxin
Heal19_RS13500	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
Heal19_RS13505	ENOG4105C59	p-type ATPase
Heal19_RS13520	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
Heal19_RS13530	ENOG4105EJ2	Transcriptional regulator
Heal19_RS13570	ENOG4105CVK	Glutamate decarboxylase
Heal19_RS13595	ENOG41075H3	AraC family transcriptional regulator
Heal19_RS13630	ENOG4108UVJ	appr-1-p processing domain protein
Heal19_RS13635	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
Heal19_RS13665	ENOG4105CGH	5'-nucleotidase
Heal19_RS13720	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
Heal19_RS13735	ENOG4105NA0	Transcriptional regulator
Heal19_RS13745	ENOG4107QHE	Choloylglycine hydrolase
Heal19_RS13760	ENOG4108UZ3	Transporter
Heal19_RS13780	ENOG4108RS6	transposase
Heal19_RS13790	ENOG4105VN1	Heat shock protein
Heal19_RS13805	ENOG4105CEN	a g-specific adenine glycosylase
Heal19_RS13815	ENOG4105K78	MarR family Transcriptional regulator
Heal19_RS13835	ENOG4108W5N	phosphatidylglycerophosphatase a
Heal19_RS13845	ENOG4105C85	amino acid
Heal19_RS13850	ENOG4105DFD	Na H antiporter
Heal19_RS13860	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
Heal19_RS13865	ENOG4105CPN	adenine deaminase
Heal19_RS13875	ENOG4105UNS	Pfam:DUF419
Heal19_RS13885	ENOG4105C59	p-type ATPase
Heal19_RS13890	ENOG4105C94	Transporter
Heal19_RS13915	ENOG4107RGM	aldo keto reductase
Heal19_RS13920	ENOG4105VG1	fes assembly suf system protein
Heal19_RS13925	ENOG4105F1A	Pyruvate formate-lyase
Heal19_RS13930	ENOG4105C6N	Formate acetyltransferase
Heal19_RS13935	ENOG4107S1E	Beta-lactamase
Heal19_RS13965	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
Heal19_RS13970	ENOG4105DSE	periplasmic solute binding protein
Heal19_RS13990	ENOG4105EUJ	GTP cyclohydrolase i
Heal19_RS14000	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
Heal19_RS14030	ENOG4105PGM	cation diffusion facilitator family transporter
Heal19_RS14040	ENOG4108UT2	hemolysin iii
Heal19_RS14060	ENOG4106F5Q	Membrane
Heal19_RS14070	ENOG4105DFH	Transport of potassium into the cell (By similarity)
Heal19_RS14075	ENOG4105CUB	amino acid
Heal19_RS14090	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
Heal19_RS14095	ENOG4105M2Z	protein tyrosine serine phosphatase
Heal19_RS14100	ENOG4107SJ1	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides (By similarity)
Heal19_RS14105	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
Heal19_RS14110	ENOG4105C83	adenylosuccinate lyase
Heal19_RS14120	ENOG4105DC8	reductase
Heal19_RS14125	ENOG4105BZW	Glycerate kinase
Heal19_RS14135	ENOG4105FE1	phytoene synthase
Heal19_RS14140	ENOG4105EWK	phytoene
Heal19_RS14440	ENOG4108RCR	degv family
Heal19_RS14475	ENOG4105G5W	regulator Fur family
Heal19_RS14505	ENOG4105C5Y	PTS System
Heal19_RS14520	ENOG410667J	hydrolase
Heal19_RS14535	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
Heal19_RS14540	ENOG41083J0	(ABC) transporter
Heal19_RS14545	ENOG4105C4B	ABC transporter, permease
Heal19_RS14565	ENOG4105C5Y	PTS System
Heal19_RS14590	ENOG4105EAB	amino acid AbC transporter
Heal19_RS14595	ENOG4105CDA	abc transporter atp-binding protein
Heal19_RS14600	ENOG4105DRP	amino acid AbC transporter
Heal19_RS14605	ENOG4105EAB	amino acid AbC transporter
Heal19_RS14610	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
Heal19_RS14615	ENOG4105W8I	Transcriptional regulator
Heal19_RS14630	ENOG4105D28	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
Heal19_RS14640	ENOG4107QJE	Chromosome Partitioning Protein
Heal19_RS14645	ENOG4105FA0	parb-like partition protein
Heal19_RS14650	ENOG4105VDK	protein, conserved in bacteria
Heal19_RS14655	ENOG4105C3G	gtp-binding protein
Heal19_RS14665	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
Heal19_RS14695	ENOG4107TCE	N-acetyltransferase
Heal19_RS14730	ENOG4105D9P	serine threonine protein kinase
Heal19_RS14740	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
Heal19_RS14755	ENOG4106F5Q	Membrane
Heal19_RS14760	ENOG4105DKJ	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
Heal19_RS14785	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
Heal19_RS14790	ENOG4105HMD	
Heal19_RS14805	ENOG4105S7A	ErfK ybiS ycfS ynhG family protein
Heal19_RS14820	ENOG4105DG4	malate L-lactate dehydrogenase
Heal19_RS14830	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
Heal19_RS14845	ENOG4108V4B	ThiJ pfpI
Heal19_RS14865	ENOG4105VUF	Transcriptional regulator
Heal19_RS14880	ENOG4105CK1	PTS System
Heal19_RS14885	ENOG4105CS2	ec 3.2.1.21
Heal19_RS14895	ENOG4105HUF	DNA protection during starvation protein
Heal19_RS14905	ENOG4107EFR	Flavocytochrome c
Heal19_RS14910	ENOG4108KB2	LysR family Transcriptional regulator
Heal19_RS14915	ENOG4105E09	nadh pyrophosphatase
Heal19_RS14925	ENOG4106KNP	GTP-binding protein LepA C-terminus
Heal19_RS14960	ENOG4105CBZ	Short-chain dehydrogenase reductase Sdr
Heal19_RS14965	ENOG4108UW5	maltose o-acetyltransferase
Heal19_RS14970	ENOG4105EMU	Dehydrogenase
Heal19_RS14985	ENOG4105EHG	Permease protein
Heal19_RS14990	ENOG4105DQ5	transport system permease protein
Heal19_RS14995	ENOG4105E0A	ABC, transporter
Heal19_RS15010	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
Heal19_RS15015	ENOG4107SET	aldo keto reductase
Heal19_RS15040	ENOG4105KVH	Transcriptional regulator
Heal19_RS15055	ENOG4105C26	Dehydrogenase
Heal19_RS15065	ENOG4107Z3H	Transcriptional regulator, TetR family
Heal19_RS15075	ENOG4108WCX	response regulator
Heal19_RS15080	ENOG4105CAQ	asparagine synthetase
Heal19_RS15090	ENOG4105F27	Major Facilitator
Heal19_RS15095	ENOG4105KVH	Transcriptional regulator
Heal19_RS15110	ENOG4105MN5	HAD-superfamily hydrolase subfamily IA variant 3
Heal19_RS15150	ENOG4105CPQ	Dehydrogenase
Heal19_RS15205	ENOG4105C59	p-type ATPase
Heal19_RS15225	ENOG4107SC7	Inner membrane transporter yjeM
Heal19_RS15240	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
Heal19_RS15255	ENOG4105BZ1	(ABC) transporter
Heal19_RS15260	ENOG4105BZ1	(ABC) transporter
Heal19_RS15275	ENOG4105CHR	reductase
Heal19_RS15305	ENOG4107GJV	short-chain dehydrogenase reductase
Heal19_RS15320	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
Heal19_RS15345	ENOG4105DSE	periplasmic solute binding protein
Heal19_RS15365	ENOG4106770	Is able to cleave peptidoglycan (By similarity)
Heal19_RS15370	ENOG4105VUF	Transcriptional regulator
Heal19_RS15380	ENOG4105CS2	ec 3.2.1.21
Heal19_RS15385	ENOG4105CK1	PTS System
Heal19_RS15390	ENOG4105VZJ	PTS System
Heal19_RS15425	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
Heal19_RS15435	ENOG4107YCR	Transcriptional regulator, ARSR family
Heal19_RS15455	ENOG4105C56	H( )-stimulated, divalent metal cation uptake system (By similarity)
Heal19_RS15480	ENOG4105CP9	extracellular ligand-binding receptor
Heal19_RS15485	ENOG4105C32	Amino acid ABC transporter (Permease)
Heal19_RS15490	ENOG4105CF8	branched-chain amino acid ABC transporter, permease
Heal19_RS15495	ENOG4105C0Z	ABC transporter
Heal19_RS15500	ENOG4108IV0	ABC, transporter
Heal19_RS15535	ENOG4105C7J	ABC transporter, permease
Heal19_RS15540	ENOG4105E2Y	ABC, transporter
Heal19_RS15545	ENOG4105CI1	PTS System
Heal19_RS15550	ENOG4108TVJ	Nitroreductase
Heal19_RS15560	ENOG4105BZ1	(ABC) transporter
Heal19_RS15565	ENOG41066F8	ROK family
Heal19_RS15590	ENOG4108UZ3	Transporter
Heal19_RS15635	ENOG4105D3H	Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity)
Heal19_RS15645	ENOG410825D	TRANSCRIPTIONal REGULATOR, LysR family
Heal19_RS15670	ENOG4107YDN	peptide deformylase
Heal19_RS15680	ENOG4105CJD	(Anaerobic) ribonucleoside-triphosphate reductase
Heal19_RS15685	ENOG4108RDD	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine (By similarity)
Heal19_RS15690	ENOG4107XTP	(EAL) domain protein
Heal19_RS15695	ENOG4105BZU	Histidine kinase
Heal19_RS15730	ENOG4105DEU	major facilitator superfamily
Heal19_RS15745	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
Heal19_RS15755	ENOG4108HCJ	Hydrolase
Heal19_RS15760	ENOG4105C5H	ABC transporter
Heal19_RS15785	ENOG4105ZT7	DNA-entry nuclease
Heal19_RS15790	ENOG4107YCR	Transcriptional regulator, ARSR family