locus-tag	class	description
B5726_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
B5726_RS00010	COG0592	DNA-directed DNA polymerase activity
B5726_RS00015	COG2501	S4 domain
B5726_RS00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
B5726_RS00025	COG0187	DNA topoisomerase II activity
B5726_RS00035	COG0360	Binds together with S18 to 16S ribosomal RNA
B5726_RS00040	COG0629	single-stranded DNA binding
B5726_RS00045	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
B5726_RS00055	COG0359	binds to the 23S rRNA
B5726_RS00060	COG0305	Participates in initiation and elongation during chromosome replication
B5726_RS00065	COG2814	Major facilitator Superfamily
B5726_RS00070	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
B5726_RS00075	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
B5726_RS00080	COG4166	transmembrane transport
B5726_RS00085	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
B5726_RS00090	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
B5726_RS00095	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
B5726_RS00100	COG0297	glycogen (starch) synthase activity
B5726_RS00105	COG0058	SHG alpha-glucan phosphorylase activity
B5726_RS00110	COG3103	Sh3 type 3 domain protein
B5726_RS00110	COG0366	Alpha amylase catalytic
B5726_RS00120	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
B5726_RS00125	COG1554	hydrolase, family 65, central catalytic
B5726_RS00135	COG1278	Cold shock
B5726_RS00215	COG4695	Portal protein
B5726_RS00235	COG1278	Cold shock
B5726_RS00250	COG0745	RESPONSE REGULATOR receiver
B5726_RS00255	COG5002	protein histidine kinase activity
B5726_RS00265	COG4853	Protein conserved in bacteria
B5726_RS00270	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
B5726_RS00275	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
B5726_RS00280	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
B5726_RS00290	COG1012	belongs to the aldehyde dehydrogenase family
B5726_RS00295	COG3586	endonuclease activity
B5726_RS00300	COG1573	uracil-dna glycosylase
B5726_RS00320	COG3976	FMN-binding domain protein
B5726_RS00320	COG1053	succinate dehydrogenase
B5726_RS00320	COG0431	NADPH-dependent FMN reductase
B5726_RS00325	COG0471	metal ion transport
B5726_RS00340	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
B5726_RS00345	COG1028	Short-chain dehydrogenase reductase Sdr
B5726_RS00355	COG0778	Nitroreductase
B5726_RS00360	COG2508	Transcriptional regulator
B5726_RS00370	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
B5726_RS00375	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
B5726_RS00390	COG2368	4-hydroxyphenylacetate
B5726_RS00410	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
B5726_RS00470	COG2267	carboxylic ester hydrolase activity
B5726_RS00475	COG3022	response to hydroperoxide
B5726_RS00485	COG4166	transmembrane transport
B5726_RS00510	COG1122	ATPase activity
B5726_RS00515	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
B5726_RS00520	COG0310	cobalt ion transport
B5726_RS00525	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
B5726_RS00530	COG3875	lactate racemase activity
B5726_RS00535	COG1691	(AIR) carboxylase
B5726_RS00540	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
B5726_RS00545	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
B5726_RS00550	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
B5726_RS00555	COG1606	tRNA processing
B5726_RS00565	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
B5726_RS00570	COG0351	phosphomethylpyrimidine kinase
B5726_RS00575	COG0352	thiamine-phosphate diphosphorylase activity
B5726_RS00585	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
B5726_RS00600	COG1113	amino acid transport
B5726_RS00610	COG2267	carboxylic ester hydrolase activity
B5726_RS00615	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
B5726_RS00620	COG0813	purine-nucleoside phosphorylase activity
B5726_RS00625	COG1983	PspC domain protein
B5726_RS00665	COG2807	transmembrane transport
B5726_RS00670	COG0656	L-ascorbic acid biosynthetic process
B5726_RS00675	COG0667	Aldo Keto reductase
B5726_RS00705	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
B5726_RS00710	COG1122	ATPase activity
B5726_RS00715	COG4720	Psort location CytoplasmicMembrane, score
B5726_RS00725	COG2188	Transcriptional regulator
B5726_RS00750	COG1028	Short-chain dehydrogenase reductase Sdr
B5726_RS00755	COG1131	(ABC) transporter
B5726_RS00770	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
B5726_RS00775	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
B5726_RS00780	COG1309	transcriptional regulator
B5726_RS00785	COG2376	Dihydroxyacetone kinase
B5726_RS00790	COG2376	Dihydroxyacetone kinase
B5726_RS00795	COG1461	Dihydroxyacetone kinase
B5726_RS00800	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
B5726_RS00805	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
B5726_RS00810	COG1609	Transcriptional regulator
B5726_RS00815	COG1609	Transcriptional regulator
B5726_RS00820	COG0366	Alpha amylase catalytic
B5726_RS00830	COG2182	Extracellular solute-binding protein
B5726_RS00835	COG1175	transmembrane transport
B5726_RS00840	COG3833	ABC-type maltose transport systems, permease component
B5726_RS00850	COG0366	Alpha amylase catalytic
B5726_RS00855	COG3842	ATPase activity
B5726_RS00910	COG1757	Na H antiporter
B5726_RS00935	COG4166	transmembrane transport
B5726_RS00940	COG4166	transmembrane transport
B5726_RS00950	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
B5726_RS00955	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
B5726_RS00960	COG0406	alpha-ribazole phosphatase activity
B5726_RS00965	COG0667	Aldo Keto reductase
B5726_RS00995	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
B5726_RS01000	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
B5726_RS01005	COG0488	(ABC) transporter
B5726_RS01015	COG4172	Belongs to the ABC transporter superfamily
B5726_RS01025	COG0386	Belongs to the glutathione peroxidase family
B5726_RS01035	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
B5726_RS01050	COG0363	glucosamine-6-phosphate deaminase activity
B5726_RS01060	COG2213	PTS system mannitol-specific
B5726_RS01070	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
B5726_RS01075	COG0246	Mannitol dehydrogenase
B5726_RS01085	COG3118	belongs to the thioredoxin family
B5726_RS01115	COG0431	NADPH-dependent FMN reductase
B5726_RS01120	COG1045	serine acetyltransferase
B5726_RS01125	COG0626	cystathionine gamma-synthase activity
B5726_RS01130	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
B5726_RS01160	COG2188	Transcriptional regulator
B5726_RS01165	COG0366	Alpha amylase catalytic
B5726_RS01170	COG2190	(PTS) system
B5726_RS01170	COG1263	PTS System
B5726_RS01170	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
B5726_RS01175	COG1263	PTS System
B5726_RS01175	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
B5726_RS01175	COG2190	(PTS) system
B5726_RS01185	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
B5726_RS01190	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
B5726_RS01195	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
B5726_RS01205	COG0163	prenyltransferase activity
B5726_RS01215	COG1959	2 iron, 2 sulfur cluster binding
B5726_RS01220	COG1309	transcriptional regulator
B5726_RS01225	COG1914	H( )-stimulated, divalent metal cation uptake system
B5726_RS01245	COG2814	Major facilitator Superfamily
B5726_RS01260	COG0745	RESPONSE REGULATOR receiver
B5726_RS01270	COG1737	Transcriptional regulator
B5726_RS01275	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
B5726_RS01290	COG1316	TRANSCRIPTIONal
B5726_RS01305	COG2357	RelA SpoT domain protein
B5726_RS01315	COG1033	growth of symbiont in host cell
B5726_RS01315	COG2409	Drug exporters of the RND superfamily
B5726_RS01315	COG2409	Drug exporters of the RND superfamily
B5726_RS01315	COG1033	growth of symbiont in host cell
B5726_RS01320	COG2818	Glycosylase
B5726_RS01330	COG0577	efflux transmembrane transporter activity
B5726_RS01335	COG1136	(ABC) transporter
B5726_RS01350	COG0741	lytic transglycosylase activity
B5726_RS01355	COG1388	LysM domain
B5726_RS01355	COG3942	CHAP domain
B5726_RS01385	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
B5726_RS01395	COG1846	Transcriptional regulator
B5726_RS01400	COG1252	NADH dehydrogenase
B5726_RS01425	COG3842	ATPase activity
B5726_RS01455	COG1725	Transcriptional regulator
B5726_RS01460	COG1131	(ABC) transporter
B5726_RS01470	COG1012	belongs to the aldehyde dehydrogenase family
B5726_RS01470	COG1454	alcohol dehydrogenase
B5726_RS01505	COG1268	BioY protein
B5726_RS01530	COG2011	ABC-type metal ion transport system permease component
B5726_RS01535	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
B5726_RS01540	COG0436	Aminotransferase
B5726_RS01555	COG1682	transport, permease protein
B5726_RS01560	COG1134	teichoic acid transport
B5726_RS01575	COG2814	Major facilitator Superfamily
B5726_RS01580	COG0004	ammonium transporteR
B5726_RS01600	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
B5726_RS01610	COG3759	membrane
B5726_RS01615	COG1881	PFAM PEBP family protein
B5726_RS01645	COG0300	oxidoreductase activity
B5726_RS01670	COG1125	glycine betaine transport
B5726_RS01680	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
B5726_RS01690	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
B5726_RS01745	COG2826	transposase and inactivated derivatives, IS30 family
B5726_RS01805	COG3973	AAA domain
B5726_RS01810	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
B5726_RS01815	COG0180	Tryptophanyl-tRNA synthetase
B5726_RS01820	COG2188	Transcriptional regulator
B5726_RS01825	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
B5726_RS01845	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
B5726_RS01850	COG0248	Ppx GppA phosphatase
B5726_RS01865	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
B5726_RS01870	COG1801	Protein of unknown function DUF72
B5726_RS01880	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
B5726_RS01880	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
B5726_RS01890	COG2814	Major facilitator Superfamily
B5726_RS01905	COG0084	hydrolase, TatD family'
B5726_RS01910	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
B5726_RS01915	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
B5726_RS01920	COG4466	Protein conserved in bacteria
B5726_RS01925	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
B5726_RS01930	COG1073	alpha beta
B5726_RS01935	COG1121	(ABC) transporter
B5726_RS01940	COG1321	iron dependent repressor
B5726_RS01940	COG1108	ABC-type Mn2 Zn2 transport systems permease components
B5726_RS01945	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
B5726_RS01950	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
B5726_RS01960	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
B5726_RS01980	COG1078	dGTPase activity
B5726_RS01985	COG0095	Lipoate-protein ligase
B5726_RS01995	COG3343	RNA polymerase activity
B5726_RS02000	COG0504	CTP synthase activity
B5726_RS02005	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
B5726_RS02010	COG0814	amino acid
B5726_RS02020	COG1760	l-serine dehydratase
B5726_RS02025	COG1760	l-serine dehydratase
B5726_RS02040	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
B5726_RS02045	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
B5726_RS02050	COG0254	rRNA binding
B5726_RS02060	COG3764	Sortase (surface protein transpeptidase)
B5726_RS02065	COG1704	LemA family
B5726_RS02070	COG0501	Belongs to the peptidase M48B family
B5726_RS02080	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
B5726_RS02095	COG0736	holo-[acyl-carrier-protein] synthase activity
B5726_RS02100	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
B5726_RS02105	COG2337	Toxic component of a toxin-antitoxin (TA) module
B5726_RS02130	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
B5726_RS02135	COG0505	Belongs to the CarA family
B5726_RS02140	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
B5726_RS02145	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
B5726_RS02150	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
B5726_RS02155	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
B5726_RS02160	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
B5726_RS02185	COG0039	L-malate dehydrogenase activity
B5726_RS02190	COG0193	aminoacyl-tRNA hydrolase activity
B5726_RS02195	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
B5726_RS02200	COG2244	polysaccharide biosynthetic process
B5726_RS02205	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
B5726_RS02215	COG1098	S1 RNA binding domain
B5726_RS02220	COG0037	tRNA processing
B5726_RS02235	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
B5726_RS02240	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
B5726_RS02245	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
B5726_RS02285	COG3104	oligopeptide transport
B5726_RS02335	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
B5726_RS02345	COG2188	Transcriptional regulator
B5726_RS02355	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
B5726_RS02360	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
B5726_RS02375	COG2183	response to ionizing radiation
B5726_RS02380	COG3091	SprT-like family
B5726_RS02385	COG0460	homoserine dehydrogenase
B5726_RS02390	COG0083	homoserine kinase activity
B5726_RS02410	COG3715	PTS system
B5726_RS02415	COG3716	PTS system mannose fructose sorbose family IID component
B5726_RS02425	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
B5726_RS02425	COG3933	PFAM sigma-54 factor interaction domain-containing protein
B5726_RS02430	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
B5726_RS02430	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
B5726_RS02435	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
B5726_RS02435	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
B5726_RS02440	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
B5726_RS02450	COG0439	Biotin carboxylase
B5726_RS02460	COG0825	malonyl-CoA metabolic process
B5726_RS02465	COG1316	TRANSCRIPTIONal
B5726_RS02475	COG0697	spore germination
B5726_RS02480	COG0588	phosphoglycerate mutase activity
B5726_RS02495	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
B5726_RS02505	COG0756	dUTP diphosphatase activity
B5726_RS02525	COG4956	integral membrane protein (PIN domain superfamily)
B5726_RS02530	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
B5726_RS02535	COG0215	cysteine-tRNA ligase activity
B5726_RS02540	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
B5726_RS02545	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
B5726_RS02560	COG0267	Belongs to the bacterial ribosomal protein bL33 family
B5726_RS02570	COG0250	Participates in transcription elongation, termination and antitermination
B5726_RS02580	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
B5726_RS02585	COG0081	regulation of translation
B5726_RS02590	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
B5726_RS02595	COG0222	ribosome binding
B5726_RS02615	COG1611	Belongs to the LOG family
B5726_RS02625	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
B5726_RS02630	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
B5726_RS02650	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
B5726_RS02655	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
B5726_RS02660	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
B5726_RS02680	COG3711	transcriptional antiterminator
B5726_RS02705	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
B5726_RS02710	COG3870	Protein conserved in bacteria
B5726_RS02715	COG0470	DNA polymerase III
B5726_RS02720	COG4467	Involved in initiation control of chromosome replication
B5726_RS02735	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
B5726_RS02740	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
B5726_RS02745	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
B5726_RS02750	COG3639	organic phosphonate transmembrane transporter activity
B5726_RS02760	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
B5726_RS02770	COG1214	PFAM Peptidase M22, glycoprotease
B5726_RS02775	COG0456	acetyltransferase
B5726_RS02780	COG0456	acetyltransferase
B5726_RS02785	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
B5726_RS02795	COG0488	(ABC) transporter
B5726_RS02800	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
B5726_RS02810	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
B5726_RS02815	COG0459	protein refolding
B5726_RS02820	COG0531	amino acid
B5726_RS02825	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
B5726_RS02830	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
B5726_RS02835	COG1739	Uncharacterized protein family UPF0029
B5726_RS02840	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
B5726_RS02855	COG0653	protein targeting
B5726_RS02860	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
B5726_RS02870	COG0745	RESPONSE REGULATOR receiver
B5726_RS02875	COG5002	protein histidine kinase activity
B5726_RS02880	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
B5726_RS02885	COG0573	inorganic phosphate transmembrane transporter activity
B5726_RS02890	COG0581	inorganic phosphate transmembrane transporter activity
B5726_RS02895	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
B5726_RS02900	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
B5726_RS02905	COG0704	Plays a role in the regulation of phosphate uptake
B5726_RS02910	COG1983	PspC domain protein
B5726_RS02915	COG1950	PFAM Membrane protein of
B5726_RS02920	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
B5726_RS02925	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
B5726_RS02930	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
B5726_RS02935	COG1210	Utp--glucose-1-phosphate uridylyltransferase
B5726_RS02945	COG0446	pyridine nucleotide-disulphide oxidoreductase
B5726_RS02950	COG0492	ferredoxin-NADP+ reductase activity
B5726_RS02955	COG2323	membrane
B5726_RS02965	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
B5726_RS02975	COG0446	pyridine nucleotide-disulphide oxidoreductase
B5726_RS02985	COG2814	Major facilitator Superfamily
B5726_RS02995	COG0556	nucleotide-excision repair
B5726_RS03000	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
B5726_RS03005	COG1854	S-ribosylhomocysteine lyase activity
B5726_RS03010	COG0137	argininosuccinate synthase activity
B5726_RS03015	COG0165	Argininosuccinate lyase
B5726_RS03025	COG1660	Displays ATPase and GTPase activities
B5726_RS03035	COG1481	regulation of sporulation
B5726_RS03045	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
B5726_RS03050	COG0740	serine-type endopeptidase activity
B5726_RS03060	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
B5726_RS03065	COG2390	Transcriptional regulator
B5726_RS03075	COG0126	phosphoglycerate kinase activity
B5726_RS03080	COG0149	triose-phosphate isomerase activity
B5726_RS03085	COG0148	phosphopyruvate hydratase activity
B5726_RS03105	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
B5726_RS03115	COG0557	exoribonuclease II activity
B5726_RS03120	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
B5726_RS03140	COG0765	amino acid transport
B5726_RS03145	COG1126	abc transporter atp-binding protein
B5726_RS03155	COG0561	phosphatase activity
B5726_RS03160	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
B5726_RS03165	COG0280	phosphate acetyltransferase
B5726_RS03170	COG0802	atpase or kinase
B5726_RS03185	COG0708	Exodeoxyribonuclease III
B5726_RS03195	COG0812	UDP-N-acetylmuramate dehydrogenase activity
B5726_RS03200	COG0025	NhaP-type Na H and K H
B5726_RS03225	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
B5726_RS03230	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
B5726_RS03240	COG0561	phosphatase activity
B5726_RS03250	COG2017	converts alpha-aldose to the beta-anomer
B5726_RS03295	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
B5726_RS03310	COG1393	Belongs to the ArsC family
B5726_RS03325	COG0477	Major facilitator Superfamily
B5726_RS03330	COG0248	Ppx GppA phosphatase
B5726_RS03335	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
B5726_RS03350	COG3475	LICD family
B5726_RS03365	COG2252	PERMEase
B5726_RS03370	COG0028	Belongs to the TPP enzyme family
B5726_RS03375	COG0196	riboflavin kinase activity
B5726_RS03380	COG0028	Belongs to the TPP enzyme family
B5726_RS03385	COG2267	carboxylic ester hydrolase activity
B5726_RS03395	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
B5726_RS03395	COG2755	lipolytic protein G-D-S-L family
B5726_RS03400	COG2936	dipeptidyl-peptidase activity
B5726_RS03415	COG0531	amino acid
B5726_RS03440	COG0194	GDP metabolic process
B5726_RS03445	COG0735	belongs to the Fur family
B5726_RS03460	COG0546	phosphoglycolate phosphatase activity
B5726_RS03465	COG0436	Aminotransferase
B5726_RS03470	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
B5726_RS03490	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
B5726_RS03495	COG0765	amino acid transport
B5726_RS03500	COG0765	amino acid transport
B5726_RS03505	COG2190	(PTS) system
B5726_RS03505	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
B5726_RS03505	COG1263	PTS System
B5726_RS03515	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
B5726_RS03515	COG1263	PTS System
B5726_RS03520	COG3394	polysaccharide catabolic process
B5726_RS03525	COG0531	amino acid
B5726_RS03535	COG1846	Transcriptional regulator
B5726_RS03565	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
B5726_RS03575	COG2076	Multidrug Resistance protein
B5726_RS03590	COG0588	phosphoglycerate mutase activity
B5726_RS03595	COG0569	domain protein
B5726_RS03595	COG0475	glutathione-regulated potassium exporter activity
B5726_RS03600	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
B5726_RS03600	COG0456	acetyltransferase
B5726_RS03605	COG3711	transcriptional antiterminator
B5726_RS03610	COG2190	(PTS) system
B5726_RS03610	COG1263	PTS System
B5726_RS03610	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
B5726_RS03615	COG2723	6-phospho-beta-galactosidase activity
B5726_RS03625	COG3973	AAA domain
B5726_RS03630	COG2070	2-Nitropropane dioxygenase
B5726_RS03635	COG1072	(Pantothenic acid kinase))
B5726_RS03640	COG0518	GMP synthase (glutamine-hydrolyzing) activity
B5726_RS03640	COG0519	Catalyzes the synthesis of GMP from XMP
B5726_RS03665	COG1196	nuclear chromosome segregation
B5726_RS03695	COG1396	sequence-specific DNA binding
B5726_RS03705	COG1266	CAAX protease self-immunity
B5726_RS03710	COG1733	regulation of RNA biosynthetic process
B5726_RS03715	COG2814	Major facilitator Superfamily
B5726_RS03750	COG2826	transposase and inactivated derivatives, IS30 family
B5726_RS03760	COG2755	lipolytic protein G-D-S-L family
B5726_RS03760	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
B5726_RS03765	COG2261	transglycosylase associated protein
B5726_RS03780	COG1302	Protein conserved in bacteria
B5726_RS03810	COG0308	aminopeptidase N
B5726_RS03840	COG0572	uridine kinase
B5726_RS03855	COG0583	DNA-binding transcription factor activity
B5726_RS03860	COG1053	succinate dehydrogenase
B5726_RS03875	COG0017	Asparaginyl-tRNA synthetase
B5726_RS03880	COG2502	aspartate--ammonia ligase
B5726_RS03885	COG4690	dipeptidase activity
B5726_RS03905	COG0514	ATP-dependent DNA helicase (RecQ)
B5726_RS03910	COG0564	pseudouridine synthase activity
B5726_RS03915	COG0640	Transcriptional regulator
B5726_RS03965	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
B5726_RS03970	COG0527	aspartate kinase activity
B5726_RS03975	COG0367	asparagine synthase
B5726_RS04025	COG2814	Major facilitator Superfamily
B5726_RS04045	COG1278	Cold shock
B5726_RS04050	COG2966	Psort location CytoplasmicMembrane, score
B5726_RS04060	COG1316	TRANSCRIPTIONal
B5726_RS04080	COG1959	2 iron, 2 sulfur cluster binding
B5726_RS04085	COG0028	Belongs to the TPP enzyme family
B5726_RS04090	COG0833	amino acid
B5726_RS04100	COG1428	Deoxynucleoside kinase
B5726_RS04105	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
B5726_RS04145	COG4463	regulation of RNA biosynthetic process
B5726_RS04160	COG0085	RNA polymerase activity
B5726_RS04165	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
B5726_RS04170	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
B5726_RS04175	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
B5726_RS04180	COG0049	tRNA binding
B5726_RS04185	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
B5726_RS04190	COG0051	transcription antitermination factor activity, RNA binding
B5726_RS04195	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
B5726_RS04200	COG0088	Forms part of the polypeptide exit tunnel
B5726_RS04205	COG0089	rRNA binding
B5726_RS04210	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
B5726_RS04215	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
B5726_RS04220	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
B5726_RS04225	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
B5726_RS04230	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
B5726_RS04235	COG0255	Belongs to the universal ribosomal protein uL29 family
B5726_RS04240	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
B5726_RS04245	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
B5726_RS04250	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
B5726_RS04255	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
B5726_RS04260	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
B5726_RS04265	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
B5726_RS04270	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
B5726_RS04275	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
B5726_RS04280	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
B5726_RS04285	COG1841	ribosomal large subunit assembly
B5726_RS04290	COG0200	Binds to the 23S rRNA
B5726_RS04300	COG0563	adenylate kinase activity
B5726_RS04305	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
B5726_RS04310	COG0257	Belongs to the bacterial ribosomal protein bL36 family
B5726_RS04315	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
B5726_RS04320	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
B5726_RS04325	COG0202	RNA polymerase activity
B5726_RS04330	COG0203	ribosomal protein L17
B5726_RS04355	COG4939	FMN-binding domain protein
B5726_RS04365	COG1122	ATPase activity
B5726_RS04370	COG1122	ATPase activity
B5726_RS04380	COG0101	tRNA pseudouridine synthase activity
B5726_RS04385	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
B5726_RS04390	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
B5726_RS04410	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
B5726_RS04415	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
B5726_RS04420	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
B5726_RS04425	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
B5726_RS04430	COG0471	metal ion transport
B5726_RS04435	COG2151	metal-sulfur cluster biosynthetic enzyme
B5726_RS04440	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
B5726_RS04450	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
B5726_RS04460	COG1917	Cupin 2, conserved barrel domain protein
B5726_RS04460	COG4977	sequence-specific DNA binding
B5726_RS04465	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
B5726_RS04470	COG1121	(ABC) transporter
B5726_RS04475	COG1108	ABC-type Mn2 Zn2 transport systems permease components
B5726_RS04480	COG0803	Belongs to the bacterial solute-binding protein 9 family
B5726_RS04490	COG0039	L-malate dehydrogenase activity
B5726_RS04495	COG0471	metal ion transport
B5726_RS04515	COG3052	prosthetic group binding
B5726_RS04535	COG0114	fumarate hydratase activity
B5726_RS04540	COG1053	succinate dehydrogenase
B5726_RS04550	COG0583	DNA-binding transcription factor activity
B5726_RS04555	COG0583	DNA-binding transcription factor activity
B5726_RS04560	COG0281	malic enzyme
B5726_RS04570	COG0531	amino acid
B5726_RS04575	COG4684	Psort location CytoplasmicMembrane, score
B5726_RS04590	COG1271	oxidase subunit
B5726_RS04595	COG1294	oxidase, subunit
B5726_RS04600	COG4988	ABC transporter
B5726_RS04605	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
B5726_RS04615	COG0142	geranyltranstransferase activity
B5726_RS04630	COG1705	Flagellar rod assembly protein muramidase FlgJ
B5726_RS04635	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
B5726_RS04640	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
B5726_RS04645	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
B5726_RS04655	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
B5726_RS04660	COG4851	CamS sex pheromone cAM373 precursor
B5726_RS04665	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
B5726_RS04670	COG0154	amidase activity
B5726_RS04675	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
B5726_RS04680	COG1597	lipid kinase activity
B5726_RS04685	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
B5726_RS04710	COG1737	Transcriptional regulator
B5726_RS04725	COG1278	Cold shock
B5726_RS04730	COG0673	inositol 2-dehydrogenase activity
B5726_RS04735	COG0513	Belongs to the DEAD box helicase family
B5726_RS04750	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
B5726_RS04775	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
B5726_RS04785	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
B5726_RS04795	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
B5726_RS04815	COG2244	polysaccharide biosynthetic process
B5726_RS04835	COG0438	transferase activity, transferring glycosyl groups
B5726_RS04850	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
B5726_RS04865	COG1088	dTDP-glucose 4,6-dehydratase activity
B5726_RS04870	COG1091	dTDP-4-dehydrorhamnose reductase activity
B5726_RS04895	COG0582	viral genome integration into host DNA
B5726_RS04905	COG0489	protein tyrosine kinase activity
B5726_RS04910	COG4464	protein tyrosine phosphatase activity
B5726_RS04915	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
B5726_RS04920	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
B5726_RS04950	COG0438	transferase activity, transferring glycosyl groups
B5726_RS04970	COG4974	Belongs to the 'phage' integrase family
B5726_RS05070	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
B5726_RS05105	COG2137	regulation of response to DNA damage stimulus
B5726_RS05110	COG3557	Belongs to the UPF0374 family
B5726_RS05135	COG0628	permease
B5726_RS05140	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
B5726_RS05145	COG2610	gluconate transmembrane transporter activity
B5726_RS05150	COG1070	Carbohydrate kinase
B5726_RS05155	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
B5726_RS05160	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
B5726_RS05165	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
B5726_RS05200	COG4166	transmembrane transport
B5726_RS05205	COG0601	transmembrane transport
B5726_RS05210	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
B5726_RS05215	COG0444	Belongs to the ABC transporter superfamily
B5726_RS05220	COG4608	Belongs to the ABC transporter superfamily
B5726_RS05230	COG2826	transposase and inactivated derivatives, IS30 family
B5726_RS05235	COG0582	viral genome integration into host DNA
B5726_RS05240	COG0542	response to heat
B5726_RS05260	COG0438	transferase activity, transferring glycosyl groups
B5726_RS05265	COG0438	transferase activity, transferring glycosyl groups
B5726_RS05275	COG1686	Belongs to the peptidase S11 family
B5726_RS05280	COG0436	Aminotransferase
B5726_RS05285	COG4703	Protein of unknown function (DUF1797)
B5726_RS05290	COG1368	sulfuric ester hydrolase activity
B5726_RS05380	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
B5726_RS05400	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
B5726_RS05415	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
B5726_RS05420	COG0833	amino acid
B5726_RS05425	COG2040	homocysteine
B5726_RS05440	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
B5726_RS05445	COG0477	Major facilitator Superfamily
B5726_RS05460	COG0438	transferase activity, transferring glycosyl groups
B5726_RS05475	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
B5726_RS05485	COG0495	leucyl-tRNA aminoacylation
B5726_RS05490	COG2244	polysaccharide biosynthetic process
B5726_RS05495	COG1187	pseudouridine synthase activity
B5726_RS05500	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
B5726_RS05505	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
B5726_RS05515	COG3842	ATPase activity
B5726_RS05525	COG0395	ABC-type sugar transport system, permease component
B5726_RS05535	COG0584	glycerophosphoryl diester phosphodiesterase
B5726_RS05540	COG1428	Deoxynucleoside kinase
B5726_RS05545	COG1970	mechanosensitive ion channel activity
B5726_RS05550	COG1511	domain protein
B5726_RS05550	COG1511	domain protein
B5726_RS05580	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
B5726_RS05585	COG0789	Transcriptional regulator
B5726_RS05595	COG0697	spore germination
B5726_RS05600	COG0561	phosphatase activity
B5726_RS05620	COG3279	Response regulator of the LytR AlgR family
B5726_RS05640	COG1846	Transcriptional regulator
B5726_RS05655	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
B5726_RS05695	COG1396	sequence-specific DNA binding
B5726_RS05970	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
B5726_RS05970	COG0646	methionine synthase
B5726_RS05975	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
B5726_RS05985	COG2046	Belongs to the sulfate adenylyltransferase family
B5726_RS05990	COG0529	Catalyzes the synthesis of activated sulfate
B5726_RS05995	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
B5726_RS06005	COG0471	metal ion transport
B5726_RS06005	COG3273	potassium ion transport
B5726_RS06010	COG0534	Mate efflux family protein
B5726_RS06030	COG2153	protein acetylation
B5726_RS06035	COG0018	arginyl-trna synthetase
B5726_RS06045	COG1136	(ABC) transporter
B5726_RS06045	COG0577	efflux transmembrane transporter activity
B5726_RS06065	COG1447	Phosphotransferase system cellobiose-specific component IIA
B5726_RS06070	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
B5726_RS06075	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
B5726_RS06080	COG2723	6-phospho-beta-galactosidase activity
B5726_RS06090	COG1376	ErfK ybiS ycfS ynhG family protein
B5726_RS06095	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
B5726_RS06100	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
B5726_RS06110	COG0436	Aminotransferase
B5726_RS06115	COG1438	arginine binding
B5726_RS06125	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
B5726_RS06130	COG3679	Belongs to the UPF0342 family
B5726_RS06135	COG0420	3'-5' exonuclease activity
B5726_RS06140	COG4717	serine-type aminopeptidase activity
B5726_RS06145	COG3481	metal-dependent phosphohydrolase, HD sub domain
B5726_RS06160	COG0583	DNA-binding transcription factor activity
B5726_RS06170	COG3976	FMN-binding domain protein
B5726_RS06170	COG1053	succinate dehydrogenase
B5726_RS06170	COG0431	NADPH-dependent FMN reductase
B5726_RS06200	COG0463	Glycosyl transferase, family 2
B5726_RS06220	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
B5726_RS06220	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
B5726_RS06225	COG0307	riboflavin synthase, alpha
B5726_RS06230	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
B5726_RS06230	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
B5726_RS06235	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
B5726_RS06245	COG2826	transposase and inactivated derivatives, IS30 family
B5726_RS06255	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
B5726_RS06265	COG0446	pyridine nucleotide-disulphide oxidoreductase
B5726_RS06300	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
B5726_RS06310	COG0537	adenosine 5'-monophosphoramidase activity
B5726_RS06315	COG1131	(ABC) transporter
B5726_RS06320	COG4473	ABC transporter
B5726_RS06325	COG0510	thiamine kinase activity
B5726_RS06330	COG0220	tRNA (guanine-N7-)-methyltransferase activity
B5726_RS06340	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
B5726_RS06345	COG1674	ftsk spoiiie
B5726_RS06350	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
B5726_RS06375	COG0719	Fe-S assembly protein
B5726_RS06380	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
B5726_RS06390	COG0719	Fe-S assembly protein
B5726_RS06405	COG1120	ATPase activity
B5726_RS06410	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
B5726_RS06415	COG0716	FMN binding
B5726_RS06430	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
B5726_RS06435	COG2223	nitrite transmembrane transporter activity
B5726_RS06440	COG2151	metal-sulfur cluster biosynthetic enzyme
B5726_RS06465	COG2197	response regulator
B5726_RS06490	COG0315	cyclic pyranopterin monophosphate synthase activity
B5726_RS06495	COG1763	Mo-molybdopterin cofactor biosynthetic process
B5726_RS06500	COG0303	'Molybdopterin
B5726_RS06510	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
B5726_RS06515	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
B5726_RS06520	COG1140	nitrate reductase beta subunit
B5726_RS06530	COG2181	nitrate reductase activity
B5726_RS06550	COG3655	Transcriptional regulator
B5726_RS06560	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
B5726_RS06560	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
B5726_RS06565	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
B5726_RS06570	COG0237	dephospho-CoA kinase activity
B5726_RS06575	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
B5726_RS06580	COG3611	Membrane attachment protein
B5726_RS06585	COG1484	DNA-dependent DNA replication
B5726_RS06590	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
B5726_RS06595	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
B5726_RS06600	COG0291	Belongs to the bacterial ribosomal protein bL35 family
B5726_RS06605	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
B5726_RS06615	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
B5726_RS06620	COG0604	alcohol dehydrogenase
B5726_RS06625	COG1733	regulation of RNA biosynthetic process
B5726_RS06635	COG1215	transferase activity, transferring glycosyl groups
B5726_RS06650	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
B5726_RS06655	COG1534	Rna-binding protein
B5726_RS06660	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
B5726_RS06665	COG1713	HD superfamily hydrolase involved in NAD metabolism
B5726_RS06670	COG0799	negative regulation of ribosome biogenesis
B5726_RS06675	COG2226	methyltransferase
B5726_RS06680	COG1323	Belongs to the UPF0348 family
B5726_RS06690	COG0333	Belongs to the bacterial ribosomal protein bL32 family
B5726_RS06705	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
B5726_RS06715	COG0745	RESPONSE REGULATOR receiver
B5726_RS06720	COG5002	protein histidine kinase activity
B5726_RS06730	COG0419	ATPase involved in DNA repair
B5726_RS06745	COG0706	membrane insertase activity
B5726_RS06750	COG1254	Belongs to the acylphosphatase family
B5726_RS06755	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
B5726_RS06765	COG1733	regulation of RNA biosynthetic process
B5726_RS06770	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
B5726_RS06775	COG0072	phenylalanine-tRNA ligase activity
B5726_RS06775	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
B5726_RS06780	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
B5726_RS06785	COG0572	uridine kinase
B5726_RS06790	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
B5726_RS06805	COG4841	protein insertion into membrane
B5726_RS06815	COG0768	penicillin binding
B5726_RS06820	COG0267	Belongs to the bacterial ribosomal protein bL33 family
B5726_RS06825	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
B5726_RS06830	COG0457	Tetratricopeptide repeat
B5726_RS06830	COG0705	Rhomboid family
B5726_RS06840	COG1940	carbohydrate kinase activity
B5726_RS06860	COG0584	glycerophosphoryl diester phosphodiesterase
B5726_RS06865	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
B5726_RS06870	COG0789	Transcriptional regulator
B5726_RS06925	COG0261	This protein binds to 23S rRNA in the presence of protein L20
B5726_RS06935	COG0211	Belongs to the bacterial ribosomal protein bL27 family
B5726_RS06940	COG0006	proline dipeptidase activity
B5726_RS06945	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
B5726_RS06950	COG1302	Protein conserved in bacteria
B5726_RS06955	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
B5726_RS06960	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
B5726_RS06965	COG1570	exodeoxyribonuclease VII activity
B5726_RS06970	COG1722	exodeoxyribonuclease VII activity
B5726_RS06975	COG0142	geranyltranstransferase activity
B5726_RS06980	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
B5726_RS06985	COG1438	arginine binding
B5726_RS06990	COG0497	DNA recombination
B5726_RS07005	COG1732	Glycine betaine
B5726_RS07020	COG0194	GDP metabolic process
B5726_RS07025	COG1758	RNA polymerase activity
B5726_RS07030	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
B5726_RS07035	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
B5726_RS07040	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
B5726_RS07045	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
B5726_RS07045	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
B5726_RS07050	COG0631	protein serine/threonine phosphatase activity
B5726_RS07055	COG2815	serine threonine protein kinase
B5726_RS07055	COG0515	serine threonine protein kinase
B5726_RS07060	COG1162	GTPase activity
B5726_RS07065	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
B5726_RS07070	COG1564	THIamine pyrophosphokinase
B5726_RS07075	COG0227	Belongs to the bacterial ribosomal protein bL28 family
B5726_RS07080	COG1302	Protein conserved in bacteria
B5726_RS07085	COG1461	Dihydroxyacetone kinase
B5726_RS07090	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
B5726_RS07095	COG0416	fatty acid biosynthetic process
B5726_RS07100	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
B5726_RS07105	COG0571	ribonuclease III activity
B5726_RS07110	COG1196	nuclear chromosome segregation
B5726_RS07115	COG0552	protein localization to endoplasmic reticulum
B5726_RS07120	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
B5726_RS07125	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
B5726_RS07130	COG0228	four-way junction DNA binding
B5726_RS07135	COG1837	Belongs to the UPF0109 family
B5726_RS07140	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
B5726_RS07145	COG0336	Belongs to the RNA methyltransferase TrmD family
B5726_RS07150	COG0335	large ribosomal subunit rRNA binding
B5726_RS07170	COG1131	(ABC) transporter
B5726_RS07185	COG0512	Glutamine amidotransferase of anthranilate synthase
B5726_RS07185	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
B5726_RS07195	COG0134	indole-3-glycerol-phosphate synthase activity
B5726_RS07200	COG0135	phosphoribosylanthranilate isomerase activity
B5726_RS07205	COG0133	tryptophan synthase activity
B5726_RS07225	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
B5726_RS07240	COG1063	alcohol dehydrogenase
B5726_RS07250	COG0300	oxidoreductase activity
B5726_RS07260	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
B5726_RS07265	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
B5726_RS07270	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
B5726_RS07275	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
B5726_RS07280	COG1028	Short-chain dehydrogenase reductase Sdr
B5726_RS07285	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
B5726_RS07300	COG0439	Biotin carboxylase
B5726_RS07315	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
B5726_RS07325	COG1811	Na channel or pump
B5726_RS07335	COG1607	acyl-coa hydrolase
B5726_RS07340	COG1162	GTPase activity
B5726_RS07350	COG0477	Major facilitator Superfamily
B5726_RS07370	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
B5726_RS07375	COG3397	chitin binding
B5726_RS07380	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
B5726_RS07390	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
B5726_RS07400	COG3152	Membrane
B5726_RS07405	COG1597	lipid kinase activity
B5726_RS07420	COG2261	transglycosylase associated protein
B5726_RS07425	COG3237	CsbD-like
B5726_RS07440	COG1942	4-Oxalocrotonate Tautomerase
B5726_RS07480	COG0531	amino acid
B5726_RS07485	COG0561	phosphatase activity
B5726_RS07490	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
B5726_RS07490	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
B5726_RS07515	COG1304	FMN binding
B5726_RS07540	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
B5726_RS07540	COG1199	ATP-dependent helicase activity
B5726_RS07555	COG0017	Asparaginyl-tRNA synthetase
B5726_RS07570	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
B5726_RS07575	COG2011	ABC-type metal ion transport system permease component
B5726_RS07580	COG1464	Belongs to the NlpA lipoprotein family
B5726_RS07595	COG1840	ABC-type Fe3 transport system, periplasmic component
B5726_RS07610	COG3331	DNA recombination
B5726_RS07615	COG4474	Belongs to the UPF0398 family
B5726_RS07620	COG3599	regulation of cell shape
B5726_RS07630	COG0116	Belongs to the methyltransferase superfamily
B5726_RS07640	COG0477	Major facilitator Superfamily
B5726_RS07645	COG1073	alpha beta
B5726_RS07655	COG1216	Glycosyl transferase, family 2
B5726_RS07675	COG1619	proteins homologs of microcin C7 resistance protein MccF
B5726_RS07700	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
B5726_RS07715	COG2759	Belongs to the formate--tetrahydrofolate ligase family
B5726_RS07720	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
B5726_RS07725	COG0564	pseudouridine synthase activity
B5726_RS07730	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
B5726_RS07735	COG0505	Belongs to the CarA family
B5726_RS07740	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
B5726_RS07750	COG5646	InterPro IPR014922
B5726_RS07775	COG1131	(ABC) transporter
B5726_RS07780	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
B5726_RS07785	COG1293	RNA-binding protein homologous to eukaryotic snRNP
B5726_RS07795	COG1307	EDD domain protein, DegV family
B5726_RS07855	COG1113	amino acid transport
B5726_RS07870	COG1620	l-lactate permease
B5726_RS07880	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
B5726_RS07890	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
B5726_RS07905	COG1846	Transcriptional regulator
B5726_RS07945	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
B5726_RS07950	COG1227	inorganic diphosphatase activity
B5726_RS07955	COG0583	DNA-binding transcription factor activity
B5726_RS07965	COG0187	DNA topoisomerase II activity
B5726_RS07970	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
B5726_RS07980	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
B5726_RS07985	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
B5726_RS07990	COG4974	Belongs to the 'phage' integrase family
B5726_RS07995	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
B5726_RS08000	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
B5726_RS08005	COG0758	DNA mediated transformation
B5726_RS08010	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
B5726_RS08015	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
B5726_RS08025	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
B5726_RS08030	COG0583	DNA-binding transcription factor activity
B5726_RS08045	COG2814	Major facilitator Superfamily
B5726_RS08050	COG3409	Peptidoglycan-binding domain 1 protein
B5726_RS08050	COG0793	Belongs to the peptidase S41A family
B5726_RS08055	COG4479	Belongs to the UPF0346 family
B5726_RS08060	COG4698	Protein conserved in bacteria
B5726_RS08065	COG2755	lipolytic protein G-D-S-L family
B5726_RS08070	COG1307	EDD domain protein, DegV family
B5726_RS08075	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
B5726_RS08080	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
B5726_RS08085	COG0488	(ABC) transporter
B5726_RS08095	COG0617	tRNA 3'-terminal CCA addition
B5726_RS08100	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
B5726_RS08105	COG0561	phosphatase activity
B5726_RS08110	COG0457	Tetratricopeptide repeat
B5726_RS08125	COG1160	GTP binding
B5726_RS08130	COG0539	negative regulation of cytoplasmic translation
B5726_RS08135	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
B5726_RS08145	COG0514	ATP-dependent DNA helicase (RecQ)
B5726_RS08155	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
B5726_RS08160	COG1187	pseudouridine synthase activity
B5726_RS08165	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
B5726_RS08170	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
B5726_RS08180	COG4974	Belongs to the 'phage' integrase family
B5726_RS08185	COG2996	Protein conserved in bacteria
B5726_RS08205	COG0205	6-phosphofructokinase activity
B5726_RS08210	COG0587	DNA-directed DNA polymerase activity
B5726_RS08220	COG0542	response to heat
B5726_RS08230	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
B5726_RS08235	COG2384	SAM-dependent methyltransferase
B5726_RS08260	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
B5726_RS08260	COG0574	Belongs to the PEP-utilizing enzyme family
B5726_RS08275	COG1846	Transcriptional regulator
B5726_RS08295	COG2217	Heavy metal translocating P-type atpase
B5726_RS08300	COG0148	phosphopyruvate hydratase activity
B5726_RS08305	COG0477	Major facilitator Superfamily
B5726_RS08315	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
B5726_RS08325	COG1349	DNA-binding transcription factor activity
B5726_RS08335	COG1393	Belongs to the ArsC family
B5726_RS08355	COG0546	phosphoglycolate phosphatase activity
B5726_RS08385	COG0583	DNA-binding transcription factor activity
B5726_RS08390	COG0604	alcohol dehydrogenase
B5726_RS08400	COG0446	pyridine nucleotide-disulphide oxidoreductase
B5726_RS08405	COG2197	response regulator
B5726_RS08410	COG4585	Histidine kinase
B5726_RS08420	COG1131	(ABC) transporter
B5726_RS08425	COG0519	Catalyzes the synthesis of GMP from XMP
B5726_RS08450	COG1131	(ABC) transporter
B5726_RS08470	COG1129	ABC transporter
B5726_RS08475	COG1725	Transcriptional regulator
B5726_RS08485	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
B5726_RS08490	COG0358	DNA primase activity
B5726_RS08495	COG0751	glycine-tRNA ligase activity
B5726_RS08500	COG0752	glycyl-tRNA synthetase alpha subunit
B5726_RS08505	COG1381	Involved in DNA repair and RecF pathway recombination
B5726_RS08510	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
B5726_RS08515	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
B5726_RS08520	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
B5726_RS08525	COG1702	phosphate starvation-inducible protein PhoH
B5726_RS08530	COG1610	YqeY-like protein
B5726_RS08535	COG0828	Belongs to the bacterial ribosomal protein bS21 family
B5726_RS08540	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
B5726_RS08550	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
B5726_RS08560	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
B5726_RS08570	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
B5726_RS08575	COG0124	histidyl-tRNA synthetase
B5726_RS08580	COG4991	sh3 domain protein
B5726_RS08580	COG3103	Sh3 type 3 domain protein
B5726_RS08580	COG0860	N-Acetylmuramoyl-L-alanine amidase
B5726_RS08585	COG3001	Fructosamine kinase
B5726_RS08590	COG0546	phosphoglycolate phosphatase activity
B5726_RS08595	COG1490	D-aminoacyl-tRNA deacylase activity
B5726_RS08600	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
B5726_RS08610	COG1385	rRNA (uridine-N3-)-methyltransferase activity
B5726_RS08615	COG2264	protein methyltransferase activity
B5726_RS08620	COG2094	Belongs to the DNA glycosylase MPG family
B5726_RS08635	COG0481	GTPase activity
B5726_RS08640	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
B5726_RS08645	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
B5726_RS08650	COG1696	Membrane protein involved in D-alanine export
B5726_RS08655	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
B5726_RS08665	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
B5726_RS08670	COG0484	heat shock protein binding
B5726_RS08675	COG0443	Heat shock 70 kDa protein
B5726_RS08680	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
B5726_RS08685	COG1420	regulation of RNA biosynthetic process
B5726_RS08690	COG3527	Alpha-acetolactate decarboxylase
B5726_RS08695	COG0196	riboflavin kinase activity
B5726_RS08700	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
B5726_RS08705	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
B5726_RS08710	COG0287	Prephenate dehydrogenase
B5726_RS08715	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
B5726_RS08725	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
B5726_RS08730	COG0738	Major facilitator superfamily
B5726_RS08735	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
B5726_RS08740	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
B5726_RS08750	COG2740	Nucleic-acid-binding protein implicated in transcription termination
B5726_RS08755	COG0195	Participates in both transcription termination and antitermination
B5726_RS08760	COG0779	Required for maturation of 30S ribosomal subunits
B5726_RS08765	COG2176	DNA-directed DNA polymerase activity
B5726_RS08770	COG0442	prolyl-tRNA aminoacylation
B5726_RS08775	COG0750	zinc metalloprotease
B5726_RS08780	COG4589	Belongs to the CDS family
B5726_RS08785	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
B5726_RS08790	COG0233	cytoplasmic translational termination
B5726_RS08795	COG0528	UMP kinase activity
B5726_RS08800	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
B5726_RS08805	COG0052	Belongs to the universal ribosomal protein uS2 family
B5726_RS08815	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
B5726_RS08820	COG2827	Endonuclease containing a URI domain
B5726_RS08825	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
B5726_RS08830	COG0204	Acyl-transferase
B5726_RS08835	COG3763	UPF0154 protein
B5726_RS08840	COG4224	UPF0291 protein
B5726_RS08845	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
B5726_RS08860	COG3425	synthase
B5726_RS08875	COG0463	Glycosyl transferase, family 2
B5726_RS08890	COG1316	TRANSCRIPTIONal
B5726_RS08895	COG1116	anion transmembrane transporter activity
B5726_RS08905	COG0772	Belongs to the SEDS family
B5726_RS08925	COG0393	Putative heavy-metal-binding
B5726_RS08940	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
B5726_RS08945	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
B5726_RS08945	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
B5726_RS08950	COG5416	Lipopolysaccharide assembly protein A domain
B5726_RS08955	COG0300	oxidoreductase activity
B5726_RS08960	COG1234	tRNA 3'-trailer cleavage
B5726_RS08970	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
B5726_RS08975	COG1349	DNA-binding transcription factor activity
B5726_RS08980	COG1105	Belongs to the carbohydrate kinase PfkB family
B5726_RS08985	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
B5726_RS08985	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
B5726_RS08985	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
B5726_RS08990	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
B5726_RS09015	COG0297	glycogen (starch) synthase activity
B5726_RS09020	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
B5726_RS09025	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
B5726_RS09035	COG0489	protein tyrosine kinase activity
B5726_RS09045	COG0322	excinuclease ABC activity
B5726_RS09050	COG1126	abc transporter atp-binding protein
B5726_RS09055	COG0765	amino acid transport
B5726_RS09075	COG0218	Necessary for normal cell division and for the maintenance of normal septation
B5726_RS09080	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
B5726_RS09085	COG0544	peptidyl-prolyl cis-trans isomerase activity
B5726_RS09090	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
B5726_RS09115	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
B5726_RS09120	COG0268	Binds directly to 16S ribosomal RNA
B5726_RS09125	COG1466	dna polymerase III delta subunit
B5726_RS09130	COG2333	competence protein COMEC
B5726_RS09130	COG0658	competence protein
B5726_RS09135	COG2131	deaminase
B5726_RS09140	COG1555	photosystem II stabilization
B5726_RS09140	COG1596	polysaccharide export
B5726_RS09145	COG3480	Lon protease (S16) C-terminal proteolytic domain
B5726_RS09150	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
B5726_RS09155	COG0742	ribosomal rna small subunit methyltransferase
B5726_RS09160	COG4471	UPF0298 protein
B5726_RS09165	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
B5726_RS09170	COG0772	Belongs to the SEDS family
B5726_RS09185	COG1217	gtp-binding protein TYPA
B5726_RS09190	COG0483	inositol monophosphate 1-phosphatase activity
B5726_RS09195	COG4476	Belongs to the UPF0223 family
B5726_RS09200	COG0039	L-malate dehydrogenase activity
B5726_RS09225	COG0242	peptide deformylase activity
B5726_RS09235	COG5503	Protein of unknown function (DUF1447)
B5726_RS09240	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
B5726_RS09245	COG1597	lipid kinase activity
B5726_RS09255	COG1388	LysM domain
B5726_RS09255	COG3584	3D domain protein
B5726_RS09260	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
B5726_RS09265	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
B5726_RS09295	COG0569	domain protein
B5726_RS09300	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
B5726_RS09305	COG0482	sulfurtransferase activity
B5726_RS09315	COG1104	cysteine desulfurase activity
B5726_RS09320	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
B5726_RS09330	COG0494	nUDIX hydrolase
B5726_RS09335	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
B5726_RS09340	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
B5726_RS09345	COG3599	regulation of cell shape
B5726_RS09355	COG0762	integral membrane protein
B5726_RS09360	COG1799	cell septum assembly
B5726_RS09375	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
B5726_RS09380	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
B5726_RS09385	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
B5726_RS09390	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
B5726_RS09395	COG0768	penicillin binding
B5726_RS09405	COG0275	rRNA processing
B5726_RS09410	COG2001	Belongs to the MraZ family
B5726_RS09430	COG1674	ftsk spoiiie
B5726_RS09435	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
B5726_RS09445	COG1114	Component of the transport system for branched-chain amino acids
B5726_RS09460	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
B5726_RS09465	COG0628	permease
B5726_RS09475	COG2706	6-phosphogluconolactonase activity
B5726_RS09480	COG3142	Participates in the control of copper homeostasis
B5726_RS09485	COG0564	pseudouridine synthase activity
B5726_RS09490	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
B5726_RS09495	COG2357	RelA SpoT domain protein
B5726_RS09505	COG1164	Oligoendopeptidase f
B5726_RS09525	COG4862	establishment of competence for transformation
B5726_RS09530	COG1393	Belongs to the ArsC family
B5726_RS09535	COG1234	tRNA 3'-trailer cleavage
B5726_RS09675	COG1098	S1 RNA binding domain
B5726_RS09685	COG0586	Pfam SNARE associated Golgi protein
B5726_RS09695	COG0647	UMP catabolic process
B5726_RS09700	COG4470	Protein conserved in bacteria
B5726_RS09705	COG0737	Belongs to the 5'-nucleotidase family
B5726_RS09720	COG1113	amino acid transport
B5726_RS09725	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
B5726_RS09730	COG0827	DNA restriction-modification system
B5726_RS09760	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
B5726_RS09770	COG0217	transcriptional regulatory protein
B5726_RS09785	COG1609	Transcriptional regulator
B5726_RS09790	COG0006	proline dipeptidase activity
B5726_RS09795	COG0789	Transcriptional regulator
B5726_RS09810	COG0668	transmembrane transport
B5726_RS09815	COG1473	amidohydrolase
B5726_RS09820	COG2171	N-acyltransferase activity
B5726_RS09825	COG0517	IMP dehydrogenase activity
B5726_RS09835	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
B5726_RS09840	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
B5726_RS09845	COG1719	4-vinyl reductase, 4VR
B5726_RS09850	COG3118	belongs to the thioredoxin family
B5726_RS09855	COG1193	negative regulation of DNA recombination
B5726_RS09865	COG3906	Belongs to the UPF0473 family
B5726_RS09870	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
B5726_RS09875	COG4472	Bacterial protein of unknown function (DUF965)
B5726_RS09880	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
B5726_RS09885	COG0513	Belongs to the DEAD box helicase family
B5726_RS09890	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
B5726_RS09895	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
B5726_RS09900	COG1862	Preprotein translocase
B5726_RS09905	COG0343	queuine tRNA-ribosyltransferase activity
B5726_RS09910	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
B5726_RS09915	COG2255	four-way junction helicase activity
B5726_RS09920	COG0632	four-way junction helicase activity
B5726_RS09950	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
B5726_RS09955	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
B5726_RS09960	COG1692	metallophosphoesterase
B5726_RS09965	COG1418	mRNA catabolic process
B5726_RS09970	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
B5726_RS09975	COG1058	Belongs to the CinA family
B5726_RS09975	COG1546	Belongs to the CinA family
B5726_RS09980	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
B5726_RS09985	COG1426	Protein conserved in bacteria
B5726_RS09990	COG0612	Peptidase, M16
B5726_RS09995	COG0612	Peptidase, M16
B5726_RS10000	COG0527	aspartate kinase activity
B5726_RS10010	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
B5726_RS10015	COG1126	abc transporter atp-binding protein
B5726_RS10020	COG0765	amino acid transport
B5726_RS10025	COG2894	cell division
B5726_RS10030	COG0850	regulation of cytokinetic process
B5726_RS10040	COG1792	Involved in formation and maintenance of cell shape
B5726_RS10045	COG1077	Cell shape determining protein MreB Mrl
B5726_RS10050	COG2003	Belongs to the UPF0758 family
B5726_RS10055	COG0285	dihydrofolate synthase activity
B5726_RS10060	COG0525	valine-tRNA ligase activity
B5726_RS10070	COG2918	glutathione biosynthetic process
B5726_RS10070	COG1181	Belongs to the D-alanine--D-alanine ligase family
B5726_RS10075	COG0301	tRNA thio-modification
B5726_RS10080	COG1104	cysteine desulfurase activity
B5726_RS10090	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
B5726_RS10095	COG1956	GAF domain-containing protein
B5726_RS10100	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
B5726_RS10105	COG4493	Belongs to the UPF0637 family
B5726_RS10120	COG0640	Transcriptional regulator
B5726_RS10125	COG0366	Alpha amylase catalytic
B5726_RS10135	COG3716	PTS system mannose fructose sorbose family IID component
B5726_RS10140	COG3715	PTS system
B5726_RS10145	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
B5726_RS10150	COG1609	Transcriptional regulator
B5726_RS10155	COG2918	glutathione biosynthetic process
B5726_RS10155	COG0189	ligase activity
B5726_RS10160	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
B5726_RS10175	COG0589	response to stress
B5726_RS10195	COG1181	Belongs to the D-alanine--D-alanine ligase family
B5726_RS10215	COG1464	Belongs to the NlpA lipoprotein family
B5726_RS10220	COG2011	ABC-type metal ion transport system permease component
B5726_RS10225	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
B5726_RS10230	COG0509	glycine decarboxylation via glycine cleavage system
B5726_RS10235	COG0772	Belongs to the SEDS family
B5726_RS10245	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
B5726_RS10250	COG1077	Cell shape determining protein MreB Mrl
B5726_RS10260	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
B5726_RS10265	COG0355	proton-transporting ATP synthase activity, rotational mechanism
B5726_RS10270	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
B5726_RS10275	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
B5726_RS10280	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
B5726_RS10285	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
B5726_RS10290	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
B5726_RS10295	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
B5726_RS10300	COG0356	it plays a direct role in the translocation of protons across the membrane
B5726_RS10305	COG2233	PERMEase
B5726_RS10315	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
B5726_RS10320	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
B5726_RS10325	COG0009	L-threonylcarbamoyladenylate synthase
B5726_RS10330	COG2890	protein-(glutamine-N5) methyltransferase activity
B5726_RS10335	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
B5726_RS10340	COG1435	thymidine kinase activity
B5726_RS10345	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
B5726_RS10350	COG3442	glutamine amidotransferase
B5726_RS10355	COG1482	cell wall glycoprotein biosynthetic process
B5726_RS10360	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
B5726_RS10370	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
B5726_RS10385	COG1132	(ABC) transporter
B5726_RS10400	COG0726	polysaccharide deacetylase
B5726_RS10510	COG1783	phage Terminase large subunit
B5726_RS10640	COG1396	sequence-specific DNA binding
B5726_RS10730	COG4695	Portal protein
B5726_RS10875	COG1132	(ABC) transporter
B5726_RS10895	COG0166	Belongs to the GPI family
B5726_RS10900	COG4975	Glucose uptake
B5726_RS10905	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
B5726_RS10910	COG3850	Histidine kinase
B5726_RS10910	COG5002	protein histidine kinase activity
B5726_RS10915	COG0745	RESPONSE REGULATOR receiver
B5726_RS10920	COG2848	UPF0210 protein
B5726_RS10925	COG3830	Belongs to the UPF0237 family
B5726_RS11025	COG0477	Major facilitator Superfamily
B5726_RS11045	COG0791	NLP P60 protein
B5726_RS11050	COG1522	sequence-specific DNA binding
B5726_RS11070	COG0488	(ABC) transporter
B5726_RS11100	COG2190	(PTS) system
B5726_RS11100	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
B5726_RS11100	COG1263	PTS System
B5726_RS11105	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
B5726_RS11110	COG1307	EDD domain protein, DegV family
B5726_RS11120	COG2873	o-acetylhomoserine
B5726_RS11125	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
B5726_RS11140	COG4120	Belongs to the binding-protein-dependent transport system permease family
B5726_RS11150	COG0446	pyridine nucleotide-disulphide oxidoreductase
B5726_RS11160	COG2084	Dehydrogenase
B5726_RS11165	COG0861	Integral membrane protein TerC family
B5726_RS11170	COG0110	maltose O-acetyltransferase activity
B5726_RS11175	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
B5726_RS11180	COG0140	phosphoribosyl-ATP diphosphatase activity
B5726_RS11185	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
B5726_RS11190	COG0107	imidazoleglycerol-phosphate synthase activity
B5726_RS11195	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
B5726_RS11200	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
B5726_RS11205	COG0131	Imidazoleglycerol-phosphate dehydratase
B5726_RS11210	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
B5726_RS11215	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
B5726_RS11220	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
B5726_RS11225	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
B5726_RS11250	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
B5726_RS11265	COG3548	integral membrane protein
B5726_RS11285	COG1368	sulfuric ester hydrolase activity
B5726_RS11290	COG0584	glycerophosphoryl diester phosphodiesterase
B5726_RS11300	COG0492	ferredoxin-NADP+ reductase activity
B5726_RS11310	COG4932	domain protein
B5726_RS11315	COG2326	polyphosphate kinase activity
B5726_RS11320	COG0778	Nitroreductase
B5726_RS11330	COG0328	RNA-DNA hybrid ribonuclease activity
B5726_RS11340	COG1609	Transcriptional regulator
B5726_RS11350	COG0673	inositol 2-dehydrogenase activity
B5726_RS11355	COG0673	inositol 2-dehydrogenase activity
B5726_RS11365	COG2826	transposase and inactivated derivatives, IS30 family
B5726_RS11375	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
B5726_RS11380	COG1335	isochorismatase
B5726_RS11390	COG1131	(ABC) transporter
B5726_RS11395	COG1725	Transcriptional regulator
B5726_RS11435	COG0028	Belongs to the TPP enzyme family
B5726_RS11445	COG1073	alpha beta
B5726_RS11450	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
B5726_RS11455	COG0626	cystathionine gamma-synthase activity
B5726_RS11485	COG0095	Lipoate-protein ligase
B5726_RS11490	COG1705	Flagellar rod assembly protein muramidase FlgJ
B5726_RS11500	COG0589	response to stress
B5726_RS11505	COG0564	pseudouridine synthase activity
B5726_RS11525	COG1396	sequence-specific DNA binding
B5726_RS11540	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
B5726_RS11550	COG2188	Transcriptional regulator
B5726_RS11555	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
B5726_RS11565	COG1418	mRNA catabolic process
B5726_RS11595	COG1253	flavin adenine dinucleotide binding
B5726_RS11600	COG1780	Probably involved in ribonucleotide reductase function
B5726_RS11605	COG0025	NhaP-type Na H and K H
B5726_RS11610	COG2814	Major facilitator Superfamily
B5726_RS11615	COG0789	Transcriptional regulator
B5726_RS11620	COG0604	alcohol dehydrogenase
B5726_RS11630	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
B5726_RS11640	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
B5726_RS11645	COG0436	Aminotransferase
B5726_RS11650	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
B5726_RS11665	COG0583	DNA-binding transcription factor activity
B5726_RS11670	COG0702	epimerase
B5726_RS11680	COG1074	ATP-dependent DNA helicase activity
B5726_RS11685	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
B5726_RS11695	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
B5726_RS11700	COG0284	orotidine-5'-phosphate decarboxylase activity
B5726_RS11705	COG0167	dihydroorotate dehydrogenase activity
B5726_RS11710	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
B5726_RS11715	COG0505	Belongs to the CarA family
B5726_RS11720	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
B5726_RS11725	COG0540	Belongs to the ATCase OTCase family
B5726_RS11730	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
B5726_RS11735	COG2508	Transcriptional regulator
B5726_RS11740	COG2233	PERMEase
B5726_RS11745	COG2252	PERMEase
B5726_RS11765	COG1215	transferase activity, transferring glycosyl groups
B5726_RS11775	COG0151	Belongs to the GarS family
B5726_RS11780	COG0138	bifunctional purine biosynthesis protein purh
B5726_RS11785	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
B5726_RS11790	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
B5726_RS11800	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
B5726_RS11805	COG0047	phosphoribosylformylglycinamidine synthase activity
B5726_RS11810	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
B5726_RS11815	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
B5726_RS11820	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
B5726_RS11830	COG3976	FMN-binding domain protein
B5726_RS11830	COG0431	NADPH-dependent FMN reductase
B5726_RS11830	COG1053	succinate dehydrogenase
B5726_RS11835	COG0431	NADPH-dependent FMN reductase
B5726_RS11835	COG3976	FMN-binding domain protein
B5726_RS11835	COG1053	succinate dehydrogenase
B5726_RS11840	COG0095	Lipoate-protein ligase
B5726_RS11845	COG2365	Tyrosine phosphatase family
B5726_RS11865	COG1136	(ABC) transporter
B5726_RS11880	COG1725	Transcriptional regulator
B5726_RS11885	COG1131	(ABC) transporter
B5726_RS11895	COG0589	response to stress
B5726_RS11905	COG2246	polysaccharide biosynthetic process
B5726_RS11925	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
B5726_RS11945	COG0366	Alpha amylase catalytic
B5726_RS11955	COG0561	phosphatase activity
B5726_RS11965	COG0110	maltose O-acetyltransferase activity
B5726_RS11970	COG0494	nUDIX hydrolase
B5726_RS12010	COG1827	regulation of RNA biosynthetic process
B5726_RS12015	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
B5726_RS12020	COG1309	transcriptional regulator
B5726_RS12030	COG1131	(ABC) transporter
B5726_RS12035	COG3048	D-serine ammonia-lyase activity
B5726_RS12040	COG2723	6-phospho-beta-galactosidase activity
B5726_RS12045	COG2723	6-phospho-beta-galactosidase activity
B5726_RS12050	COG1447	Phosphotransferase system cellobiose-specific component IIA
B5726_RS12055	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
B5726_RS12060	COG2188	Transcriptional regulator
B5726_RS12065	COG1216	Glycosyl transferase, family 2
B5726_RS12080	COG0561	phosphatase activity
B5726_RS12085	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
B5726_RS12110	COG0716	FMN binding
B5726_RS12130	COG0710	3-dehydroquinate dehydratase activity
B5726_RS12135	COG0531	amino acid
B5726_RS12180	COG4720	Psort location CytoplasmicMembrane, score
B5726_RS12185	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
B5726_RS12200	COG4990	cell redox homeostasis
B5726_RS12220	COG1811	Na channel or pump
B5726_RS12225	COG0789	Transcriptional regulator
B5726_RS12225	COG4978	Transcriptional regulator
B5726_RS12240	COG0577	efflux transmembrane transporter activity
B5726_RS12245	COG1136	(ABC) transporter
B5726_RS12290	COG2814	Major facilitator Superfamily
B5726_RS12300	COG2814	Major facilitator Superfamily
B5726_RS12310	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
B5726_RS12315	COG2855	membrane
B5726_RS12320	COG0583	DNA-binding transcription factor activity
B5726_RS12330	COG0438	transferase activity, transferring glycosyl groups
B5726_RS12345	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
B5726_RS12360	COG4152	abc transporter atp-binding protein
B5726_RS12370	COG4221	oxidoreductase activity
B5726_RS12385	COG0789	Transcriptional regulator
B5726_RS12405	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
B5726_RS12430	COG0456	acetyltransferase
B5726_RS12455	COG0583	DNA-binding transcription factor activity
B5726_RS12465	COG1063	alcohol dehydrogenase
B5726_RS12470	COG1028	Short-chain dehydrogenase reductase Sdr
B5726_RS12480	COG0589	response to stress
B5726_RS12485	COG0110	maltose O-acetyltransferase activity
B5726_RS12490	COG1011	Hydrolase
B5726_RS12505	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
B5726_RS12515	COG0667	Aldo Keto reductase
B5726_RS12520	COG1132	(ABC) transporter
B5726_RS12525	COG1132	(ABC) transporter
B5726_RS12530	COG2814	Major facilitator Superfamily
B5726_RS12550	COG1511	domain protein
B5726_RS12550	COG1511	domain protein
B5726_RS12560	COG0640	Transcriptional regulator
B5726_RS12590	COG0488	(ABC) transporter
B5726_RS12615	COG2200	EAL domain
B5726_RS12625	COG1328	CTP reductase activity
B5726_RS12645	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
B5726_RS12665	COG0583	DNA-binding transcription factor activity
B5726_RS12675	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
B5726_RS12735	COG0697	spore germination
B5726_RS12740	COG2755	lipolytic protein G-D-S-L family
B5726_RS12740	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
B5726_RS12760	COG1940	carbohydrate kinase activity
B5726_RS12765	COG1132	(ABC) transporter
B5726_RS12775	COG0778	Nitroreductase
B5726_RS12780	COG1263	PTS System
B5726_RS12780	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
B5726_RS12780	COG2190	(PTS) system
B5726_RS12785	COG1116	anion transmembrane transporter activity
B5726_RS12790	COG4120	Belongs to the binding-protein-dependent transport system permease family
B5726_RS12820	COG0617	tRNA 3'-terminal CCA addition
B5726_RS12820	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
B5726_RS12820	COG3620	sequence-specific DNA binding
B5726_RS12825	COG0410	ABC transporter
B5726_RS12840	COG0559	Belongs to the binding-protein-dependent transport system permease family
B5726_RS12855	COG5549	protein import
B5726_RS12855	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
B5726_RS12860	COG2246	polysaccharide biosynthetic process
B5726_RS12870	COG1914	H( )-stimulated, divalent metal cation uptake system
B5726_RS12890	COG0640	Transcriptional regulator
B5726_RS12910	COG1136	(ABC) transporter
B5726_RS12910	COG0577	efflux transmembrane transporter activity
B5726_RS12945	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
B5726_RS12950	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
B5726_RS12955	COG2723	6-phospho-beta-galactosidase activity
B5726_RS12965	COG0789	Transcriptional regulator
B5726_RS12970	COG0741	lytic transglycosylase activity
B5726_RS12975	COG0741	lytic transglycosylase activity
B5726_RS12990	COG0803	Belongs to the bacterial solute-binding protein 9 family
B5726_RS13015	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
B5726_RS13025	COG0789	Transcriptional regulator
B5726_RS13030	COG2826	transposase and inactivated derivatives, IS30 family
B5726_RS13045	COG0667	Aldo Keto reductase
B5726_RS13065	COG1028	Short-chain dehydrogenase reductase Sdr
B5726_RS13070	COG1073	alpha beta
B5726_RS13090	COG4221	oxidoreductase activity
B5726_RS13120	COG1028	Short-chain dehydrogenase reductase Sdr
B5726_RS13135	COG1132	(ABC) transporter
B5726_RS13140	COG1132	(ABC) transporter
B5726_RS13145	COG1473	amidohydrolase
B5726_RS13150	COG1028	Short-chain dehydrogenase reductase Sdr
B5726_RS13165	COG0531	amino acid
B5726_RS13190	COG2217	Heavy metal translocating P-type atpase
B5726_RS13250	COG1063	alcohol dehydrogenase
B5726_RS13290	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
B5726_RS13295	COG1733	regulation of RNA biosynthetic process
B5726_RS13300	COG2814	Major facilitator Superfamily
B5726_RS13310	COG0367	asparagine synthase
B5726_RS13320	COG3279	Response regulator of the LytR AlgR family
B5726_RS13335	COG1309	transcriptional regulator
B5726_RS13345	COG1012	belongs to the aldehyde dehydrogenase family
B5726_RS13360	COG1733	regulation of RNA biosynthetic process
B5726_RS13365	COG1028	Short-chain dehydrogenase reductase Sdr
B5726_RS13385	COG4989	oxidoreductase activity
B5726_RS13390	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
B5726_RS13400	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
B5726_RS13405	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
B5726_RS13410	COG1309	transcriptional regulator
B5726_RS13420	COG4221	oxidoreductase activity
B5726_RS13425	COG0110	maltose O-acetyltransferase activity
B5726_RS13430	COG1028	Short-chain dehydrogenase reductase Sdr
B5726_RS13465	COG0481	GTPase activity
B5726_RS13475	COG2816	NAD+ diphosphatase activity
B5726_RS13485	COG0431	NADPH-dependent FMN reductase
B5726_RS13485	COG1053	succinate dehydrogenase
B5726_RS13485	COG3976	FMN-binding domain protein
B5726_RS13495	COG0783	Belongs to the Dps family
B5726_RS13505	COG3976	FMN-binding domain protein
B5726_RS13505	COG0431	NADPH-dependent FMN reductase
B5726_RS13505	COG1053	succinate dehydrogenase
B5726_RS13510	COG0583	DNA-binding transcription factor activity
B5726_RS13520	COG0789	Transcriptional regulator
B5726_RS13535	COG2826	transposase and inactivated derivatives, IS30 family
B5726_RS13580	COG1511	domain protein
B5726_RS13590	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
B5726_RS13600	COG2226	methyltransferase
B5726_RS13605	COG0588	phosphoglycerate mutase activity
B5726_RS13610	COG0628	permease
B5726_RS13615	COG1846	Transcriptional regulator
B5726_RS13615	COG1940	carbohydrate kinase activity
B5726_RS13625	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
B5726_RS13635	COG0515	serine threonine protein kinase
B5726_RS13635	COG2815	serine threonine protein kinase
B5726_RS13675	COG1247	-acetyltransferase
B5726_RS13680	COG1686	Belongs to the peptidase S11 family
B5726_RS13700	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
B5726_RS13705	COG0516	GMP reductase activity
B5726_RS13705	COG0517	IMP dehydrogenase activity
B5726_RS13715	COG0012	GTP binding
B5726_RS13720	COG4481	Protein conserved in bacteria
B5726_RS13725	COG1475	DNA binding
B5726_RS13730	COG1192	Involved in chromosome partitioning
B5726_RS13740	COG0357	Ribosomal RNA small subunit methyltransferase G
B5726_RS13745	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
B5726_RS13770	COG0583	DNA-binding transcription factor activity
B5726_RS13775	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
B5726_RS13780	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
B5726_RS13785	COG0765	amino acid transport
B5726_RS13790	COG1126	abc transporter atp-binding protein
B5726_RS13795	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
B5726_RS13820	COG1263	PTS System
B5726_RS13820	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
B5726_RS13820	COG2190	(PTS) system
B5726_RS13825	COG0366	Alpha amylase catalytic
B5726_RS13830	COG1609	Transcriptional regulator
B5726_RS13845	COG0390	transport system, permease component
B5726_RS13850	COG4619	ABC transporter
B5726_RS13855	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
B5726_RS13870	COG1263	PTS System
B5726_RS13870	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
B5726_RS13870	COG2190	(PTS) system
B5726_RS13885	COG0583	DNA-binding transcription factor activity
B5726_RS13895	COG0561	phosphatase activity
B5726_RS13905	COG0383	alpha-mannosidase activity
B5726_RS13910	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
B5726_RS13910	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
B5726_RS13910	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
B5726_RS13915	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
B5726_RS13920	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
B5726_RS13920	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
B5726_RS13920	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
B5726_RS13940	COG1263	PTS System
B5726_RS13940	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
B5726_RS13940	COG2190	(PTS) system
B5726_RS13970	COG0735	belongs to the Fur family
B5726_RS13995	COG1380	Effector of murein hydrolase LrgA
B5726_RS14005	COG1307	EDD domain protein, DegV family
B5726_RS14015	COG2738	Putative neutral zinc metallopeptidase
B5726_RS14020	COG1233	COG1233 Phytoene dehydrogenase and related
B5726_RS14025	COG1562	ergosterol biosynthetic process
B5726_RS14035	COG1929	Belongs to the glycerate kinase type-1 family
B5726_RS14050	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
B5726_RS14055	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
B5726_RS14060	COG0516	GMP reductase activity
B5726_RS14065	COG2365	Tyrosine phosphatase family
B5726_RS14070	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
B5726_RS14080	COG1511	domain protein
B5726_RS14095	COG0531	amino acid
B5726_RS14100	COG3158	transport of potassium into the cell
B5726_RS14105	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
B5726_RS14110	COG0628	permease
B5726_RS14115	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
B5726_RS14130	COG1272	protein, Hemolysin III
B5726_RS14135	COG0640	Transcriptional regulator
B5726_RS14170	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
B5726_RS14180	COG0302	gtp cyclohydrolase
B5726_RS14185	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
B5726_RS14205	COG0803	Belongs to the bacterial solute-binding protein 9 family
B5726_RS14210	COG2814	Major facilitator Superfamily
B5726_RS14240	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
B5726_RS14245	COG1882	Formate acetyltransferase
B5726_RS14250	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
B5726_RS14260	COG2151	metal-sulfur cluster biosynthetic enzyme
B5726_RS14265	COG4989	oxidoreductase activity
B5726_RS14300	COG2217	Heavy metal translocating P-type atpase
B5726_RS14310	COG2315	Protein conserved in bacteria
B5726_RS14320	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
B5726_RS14325	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
B5726_RS14335	COG1757	Na H antiporter
B5726_RS14340	COG1113	amino acid transport
B5726_RS14350	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
B5726_RS14365	COG1393	Belongs to the ArsC family
B5726_RS14370	COG3189	MarR family transcriptional regulator
B5726_RS14380	COG1194	a g-specific adenine glycosylase
B5726_RS14395	COG0071	Belongs to the small heat shock protein (HSP20) family
B5726_RS14415	COG0697	spore germination
B5726_RS14430	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
B5726_RS14455	COG0477	Major facilitator Superfamily
B5726_RS14585	COG0737	Belongs to the 5'-nucleotidase family
B5726_RS14600	COG0656	L-ascorbic acid biosynthetic process
B5726_RS14620	COG1968	undecaprenyl-diphosphatase activity
B5726_RS14625	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
B5726_RS14660	COG2207	Transcriptional regulator
B5726_RS14685	COG0076	glutamate decarboxylase activity
B5726_RS14735	COG2226	methyltransferase
B5726_RS14755	COG2217	Heavy metal translocating P-type atpase
B5726_RS14760	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
B5726_RS14765	COG3118	belongs to the thioredoxin family
B5726_RS14770	COG1937	Protein conserved in bacteria
B5726_RS14790	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
B5726_RS14795	COG3590	peptidase
B5726_RS14820	COG0446	pyridine nucleotide-disulphide oxidoreductase
B5726_RS14870	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
B5726_RS14880	COG1114	Component of the transport system for branched-chain amino acids
B5726_RS14890	COG1874	Beta-galactosidase
B5726_RS14895	COG1609	Transcriptional regulator
B5726_RS14905	COG0477	Major facilitator Superfamily
B5726_RS14925	COG2184	nucleotidyltransferase activity
B5726_RS14930	COG2944	sequence-specific DNA binding
B5726_RS14935	COG1609	Transcriptional regulator
B5726_RS14940	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
B5726_RS14945	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
B5726_RS14950	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
B5726_RS14970	COG2017	converts alpha-aldose to the beta-anomer
B5726_RS14975	COG1609	Transcriptional regulator
B5726_RS14980	COG0667	Aldo Keto reductase
B5726_RS15000	COG0710	3-dehydroquinate dehydratase activity
B5726_RS15005	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
B5726_RS15010	COG0583	DNA-binding transcription factor activity
B5726_RS15015	COG2271	Major facilitator Superfamily
B5726_RS15030	COG1028	Short-chain dehydrogenase reductase Sdr
B5726_RS15045	COG2271	Major facilitator Superfamily
B5726_RS15060	COG2267	carboxylic ester hydrolase activity
B5726_RS15065	COG2188	Transcriptional regulator
B5726_RS15070	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
B5726_RS15075	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
B5726_RS15080	COG2971	BadF BadG BcrA BcrD
B5726_RS15090	COG2723	6-phospho-beta-galactosidase activity
B5726_RS15100	COG3711	transcriptional antiterminator
B5726_RS15110	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
B5726_RS15115	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
B5726_RS15115	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
B5726_RS15120	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
B5726_RS15120	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
B5726_RS15120	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
B5726_RS15125	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
B5726_RS15125	COG1263	PTS System
B5726_RS15125	COG2190	(PTS) system
B5726_RS15130	COG1737	Transcriptional regulator
B5726_RS15135	COG1263	PTS System
B5726_RS15135	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
B5726_RS15140	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
B5726_RS15150	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
B5726_RS15160	COG2723	6-phospho-beta-galactosidase activity
B5726_RS15165	COG2723	6-phospho-beta-galactosidase activity
B5726_RS15170	COG1263	PTS System
B5726_RS15170	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
B5726_RS15170	COG2190	(PTS) system
B5726_RS15190	COG2211	Major facilitator Superfamily
B5726_RS15205	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
B5726_RS15220	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
B5726_RS15225	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
B5726_RS15230	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
B5726_RS15230	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
B5726_RS15230	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
B5726_RS15235	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
B5726_RS15240	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
B5726_RS15250	COG3711	transcriptional antiterminator
B5726_RS15260	COG3775	system Galactitol-specific IIC component
B5726_RS15265	COG3414	Phosphotransferase system galactitol-specific IIB component
B5726_RS15275	COG1349	DNA-binding transcription factor activity
B5726_RS15280	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
B5726_RS15285	COG0726	polysaccharide deacetylase
B5726_RS15285	COG1649	PFAM Uncharacterised BCR, COG1649
B5726_RS15305	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
B5726_RS15335	COG2261	transglycosylase associated protein
B5726_RS15345	COG1393	Belongs to the ArsC family
B5726_RS15365	COG4512	PFAM Accessory gene regulator B
B5726_RS15380	COG1304	FMN binding
B5726_RS15385	COG0028	Belongs to the TPP enzyme family
B5726_RS15390	COG1959	2 iron, 2 sulfur cluster binding
B5726_RS15395	COG0028	Belongs to the TPP enzyme family
B5726_RS15410	COG0235	Class ii aldolase
B5726_RS15415	COG4806	L-rhamnose isomerase
B5726_RS15420	COG3254	rhamnose metabolic process
B5726_RS15425	COG1070	Carbohydrate kinase
B5726_RS15430	COG2814	Major facilitator Superfamily
B5726_RS15440	COG2826	transposase and inactivated derivatives, IS30 family
B5726_RS15460	COG4975	Glucose uptake
B5726_RS15465	COG1869	D-ribose catabolic process
B5726_RS15475	COG1609	Transcriptional regulator
B5726_RS15480	COG1454	alcohol dehydrogenase
B5726_RS15480	COG1012	belongs to the aldehyde dehydrogenase family
B5726_RS15490	COG1695	Transcriptional regulator
B5726_RS15495	COG3479	Phenolic acid decarboxylase
B5726_RS15510	COG1307	EDD domain protein, DegV family
B5726_RS15550	COG0445	tRNA wobble uridine modification
B5726_RS15555	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
B5726_RS15560	COG1847	R3H domain protein
B5726_RS15570	COG4166	transmembrane transport
B5726_RS15575	COG0706	membrane insertase activity
B5726_RS15580	COG0594	ribonuclease P activity
B5726_RS15585	COG0230	Belongs to the bacterial ribosomal protein bL34 family