locus-tag	class	description
A8704_RS00010	COG4990	cell redox homeostasis
A8704_RS00025	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
A8704_RS00030	COG4720	Psort location CytoplasmicMembrane, score
A8704_RS00075	COG0531	amino acid
A8704_RS00080	COG0710	3-dehydroquinate dehydratase activity
A8704_RS00100	COG0716	FMN binding
A8704_RS00125	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
A8704_RS00145	COG1216	Glycosyl transferase, family 2
A8704_RS00150	COG2188	Transcriptional regulator
A8704_RS00155	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
A8704_RS00160	COG1447	Phosphotransferase system cellobiose-specific component IIA
A8704_RS00165	COG2723	6-phospho-beta-galactosidase activity
A8704_RS00170	COG2723	6-phospho-beta-galactosidase activity
A8704_RS00175	COG3048	D-serine ammonia-lyase activity
A8704_RS00180	COG1131	(ABC) transporter
A8704_RS00190	COG1309	transcriptional regulator
A8704_RS00195	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
A8704_RS00200	COG1827	regulation of RNA biosynthetic process
A8704_RS00235	COG0494	nUDIX hydrolase
A8704_RS00240	COG0110	maltose O-acetyltransferase activity
A8704_RS00250	COG0561	phosphatase activity
A8704_RS00260	COG0366	Alpha amylase catalytic
A8704_RS00280	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
A8704_RS00300	COG2246	polysaccharide biosynthetic process
A8704_RS00310	COG0589	response to stress
A8704_RS00320	COG1131	(ABC) transporter
A8704_RS00325	COG1725	Transcriptional regulator
A8704_RS00340	COG1136	(ABC) transporter
A8704_RS00360	COG2365	Tyrosine phosphatase family
A8704_RS00365	COG0095	Lipoate-protein ligase
A8704_RS00370	COG3976	FMN-binding domain protein
A8704_RS00370	COG1053	succinate dehydrogenase
A8704_RS00370	COG0431	NADPH-dependent FMN reductase
A8704_RS00375	COG1053	succinate dehydrogenase
A8704_RS00375	COG3976	FMN-binding domain protein
A8704_RS00375	COG0431	NADPH-dependent FMN reductase
A8704_RS00385	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
A8704_RS00390	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
A8704_RS00395	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
A8704_RS00400	COG0047	phosphoribosylformylglycinamidine synthase activity
A8704_RS00405	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
A8704_RS00415	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
A8704_RS00420	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
A8704_RS00425	COG0138	bifunctional purine biosynthesis protein purh
A8704_RS00430	COG0151	Belongs to the GarS family
A8704_RS00440	COG1215	transferase activity, transferring glycosyl groups
A8704_RS00460	COG2252	PERMEase
A8704_RS00465	COG2233	PERMEase
A8704_RS00470	COG2508	Transcriptional regulator
A8704_RS00475	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
A8704_RS00480	COG0540	Belongs to the ATCase OTCase family
A8704_RS00485	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
A8704_RS00490	COG0505	Belongs to the CarA family
A8704_RS00495	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
A8704_RS00500	COG0167	dihydroorotate dehydrogenase activity
A8704_RS00505	COG0284	orotidine-5'-phosphate decarboxylase activity
A8704_RS00510	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
A8704_RS00520	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
A8704_RS00525	COG1074	ATP-dependent DNA helicase activity
A8704_RS00535	COG0702	epimerase
A8704_RS00540	COG0583	DNA-binding transcription factor activity
A8704_RS00555	COG0436	Aminotransferase
A8704_RS00560	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
A8704_RS00565	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
A8704_RS00575	COG0604	alcohol dehydrogenase
A8704_RS00580	COG0789	Transcriptional regulator
A8704_RS00585	COG2814	Major facilitator Superfamily
A8704_RS00590	COG0025	NhaP-type Na H and K H
A8704_RS00595	COG1780	Probably involved in ribonucleotide reductase function
A8704_RS00600	COG1253	flavin adenine dinucleotide binding
A8704_RS00620	COG3293	Transposase
A8704_RS00640	COG1418	mRNA catabolic process
A8704_RS00650	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
A8704_RS00655	COG2188	Transcriptional regulator
A8704_RS00665	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
A8704_RS00680	COG1396	sequence-specific DNA binding
A8704_RS00685	COG4640	response to antibiotic
A8704_RS00715	COG0564	pseudouridine synthase activity
A8704_RS00720	COG0589	response to stress
A8704_RS00725	COG2188	Transcriptional regulator
A8704_RS00730	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
A8704_RS00735	COG3715	PTS system
A8704_RS00740	COG3716	PTS system mannose fructose sorbose family IID component
A8704_RS00755	COG1705	Flagellar rod assembly protein muramidase FlgJ
A8704_RS00760	COG0095	Lipoate-protein ligase
A8704_RS00790	COG0626	cystathionine gamma-synthase activity
A8704_RS00795	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
A8704_RS00800	COG1073	alpha beta
A8704_RS00810	COG0028	Belongs to the TPP enzyme family
A8704_RS00850	COG1725	Transcriptional regulator
A8704_RS00855	COG1131	(ABC) transporter
A8704_RS00865	COG1335	isochorismatase
A8704_RS00870	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
A8704_RS00880	COG0673	inositol 2-dehydrogenase activity
A8704_RS00895	COG1609	Transcriptional regulator
A8704_RS00905	COG0328	RNA-DNA hybrid ribonuclease activity
A8704_RS00915	COG0778	Nitroreductase
A8704_RS00920	COG2326	polyphosphate kinase activity
A8704_RS00935	COG0492	ferredoxin-NADP+ reductase activity
A8704_RS00945	COG0584	glycerophosphoryl diester phosphodiesterase
A8704_RS00950	COG1368	sulfuric ester hydrolase activity
A8704_RS00970	COG3548	integral membrane protein
A8704_RS00985	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
A8704_RS00995	COG0300	oxidoreductase activity
A8704_RS01000	COG0789	Transcriptional regulator
A8704_RS01020	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
A8704_RS01025	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
A8704_RS01030	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
A8704_RS01035	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
A8704_RS01040	COG0131	Imidazoleglycerol-phosphate dehydratase
A8704_RS01045	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
A8704_RS01050	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
A8704_RS01055	COG0107	imidazoleglycerol-phosphate synthase activity
A8704_RS01060	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
A8704_RS01065	COG0140	phosphoribosyl-ATP diphosphatase activity
A8704_RS01075	COG0110	maltose O-acetyltransferase activity
A8704_RS01080	COG0861	Integral membrane protein TerC family
A8704_RS01085	COG2084	Dehydrogenase
A8704_RS01090	COG0446	pyridine nucleotide-disulphide oxidoreductase
A8704_RS01100	COG4120	Belongs to the binding-protein-dependent transport system permease family
A8704_RS01110	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
A8704_RS01115	COG2873	o-acetylhomoserine
A8704_RS01125	COG1307	EDD domain protein, DegV family
A8704_RS01130	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
A8704_RS01135	COG1263	PTS System
A8704_RS01135	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
A8704_RS01135	COG2190	(PTS) system
A8704_RS01155	COG0488	(ABC) transporter
A8704_RS01160	COG3293	Transposase
A8704_RS01185	COG1522	sequence-specific DNA binding
A8704_RS01190	COG0791	NLP P60 protein
A8704_RS01205	COG0477	Major facilitator Superfamily
A8704_RS01230	COG3830	Belongs to the UPF0237 family
A8704_RS01235	COG2848	UPF0210 protein
A8704_RS01240	COG0745	RESPONSE REGULATOR receiver
A8704_RS01245	COG3850	Histidine kinase
A8704_RS01245	COG5002	protein histidine kinase activity
A8704_RS01250	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
A8704_RS01255	COG4975	Glucose uptake
A8704_RS01260	COG0166	Belongs to the GPI family
A8704_RS01270	COG3293	Transposase
A8704_RS01280	COG1136	(ABC) transporter
A8704_RS01280	COG0577	efflux transmembrane transporter activity
A8704_RS01290	COG1132	(ABC) transporter
A8704_RS01295	COG4932	domain protein
A8704_RS01295	COG4886	Leucine-rich repeat (LRR) protein
A8704_RS01320	COG4974	Belongs to the 'phage' integrase family
A8704_RS01385	COG4695	Portal protein
A8704_RS01480	COG1396	sequence-specific DNA binding
A8704_RS01590	COG1783	phage Terminase large subunit
A8704_RS01710	COG0726	polysaccharide deacetylase
A8704_RS01725	COG1132	(ABC) transporter
A8704_RS01740	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
A8704_RS01750	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
A8704_RS01755	COG1482	cell wall glycoprotein biosynthetic process
A8704_RS01760	COG3442	glutamine amidotransferase
A8704_RS01765	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
A8704_RS01770	COG1435	thymidine kinase activity
A8704_RS01775	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
A8704_RS01780	COG2890	protein-(glutamine-N5) methyltransferase activity
A8704_RS01785	COG0009	L-threonylcarbamoyladenylate synthase
A8704_RS01790	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
A8704_RS01795	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
A8704_RS01805	COG2233	PERMEase
A8704_RS01810	COG0356	it plays a direct role in the translocation of protons across the membrane
A8704_RS01815	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
A8704_RS01820	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
A8704_RS01825	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
A8704_RS01830	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
A8704_RS01835	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
A8704_RS01840	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
A8704_RS01845	COG0355	proton-transporting ATP synthase activity, rotational mechanism
A8704_RS01850	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
A8704_RS01860	COG1077	Cell shape determining protein MreB Mrl
A8704_RS01865	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
A8704_RS01875	COG0772	Belongs to the SEDS family
A8704_RS01880	COG0509	glycine decarboxylation via glycine cleavage system
A8704_RS01885	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
A8704_RS01890	COG2011	ABC-type metal ion transport system permease component
A8704_RS01895	COG1464	Belongs to the NlpA lipoprotein family
A8704_RS01915	COG1181	Belongs to the D-alanine--D-alanine ligase family
A8704_RS01935	COG0589	response to stress
A8704_RS01950	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
A8704_RS01955	COG2918	glutathione biosynthetic process
A8704_RS01955	COG0189	ligase activity
A8704_RS01960	COG0640	Transcriptional regulator
A8704_RS01975	COG4493	Belongs to the UPF0637 family
A8704_RS01980	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
A8704_RS01985	COG1956	GAF domain-containing protein
A8704_RS01990	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
A8704_RS02000	COG1104	cysteine desulfurase activity
A8704_RS02005	COG0301	tRNA thio-modification
A8704_RS02010	COG1181	Belongs to the D-alanine--D-alanine ligase family
A8704_RS02010	COG2918	glutathione biosynthetic process
A8704_RS02020	COG0525	valine-tRNA ligase activity
A8704_RS02025	COG0285	dihydrofolate synthase activity
A8704_RS02030	COG2003	Belongs to the UPF0758 family
A8704_RS02035	COG1077	Cell shape determining protein MreB Mrl
A8704_RS02040	COG1792	Involved in formation and maintenance of cell shape
A8704_RS02050	COG0850	regulation of cytokinetic process
A8704_RS02055	COG2894	cell division
A8704_RS02060	COG0765	amino acid transport
A8704_RS02065	COG1126	abc transporter atp-binding protein
A8704_RS02070	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
A8704_RS02075	COG0527	aspartate kinase activity
A8704_RS02080	COG0612	Peptidase, M16
A8704_RS02085	COG0612	Peptidase, M16
A8704_RS02090	COG1426	Protein conserved in bacteria
A8704_RS02095	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
A8704_RS02100	COG1546	Belongs to the CinA family
A8704_RS02100	COG1058	Belongs to the CinA family
A8704_RS02105	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
A8704_RS02110	COG1418	mRNA catabolic process
A8704_RS02115	COG1692	metallophosphoesterase
A8704_RS02120	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
A8704_RS02125	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
A8704_RS02155	COG0632	four-way junction helicase activity
A8704_RS02160	COG2255	four-way junction helicase activity
A8704_RS02165	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
A8704_RS02170	COG0343	queuine tRNA-ribosyltransferase activity
A8704_RS02175	COG1862	Preprotein translocase
A8704_RS02180	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
A8704_RS02185	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
A8704_RS02190	COG0513	Belongs to the DEAD box helicase family
A8704_RS02195	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
A8704_RS02200	COG4472	Bacterial protein of unknown function (DUF965)
A8704_RS02205	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
A8704_RS02210	COG3906	Belongs to the UPF0473 family
A8704_RS02220	COG1193	negative regulation of DNA recombination
A8704_RS02225	COG3118	belongs to the thioredoxin family
A8704_RS02230	COG1719	4-vinyl reductase, 4VR
A8704_RS02235	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
A8704_RS02240	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
A8704_RS02250	COG0517	IMP dehydrogenase activity
A8704_RS02255	COG2171	N-acyltransferase activity
A8704_RS02260	COG1473	amidohydrolase
A8704_RS02265	COG0668	transmembrane transport
A8704_RS02280	COG0789	Transcriptional regulator
A8704_RS02285	COG0006	proline dipeptidase activity
A8704_RS02290	COG1609	Transcriptional regulator
A8704_RS02305	COG0217	transcriptional regulatory protein
A8704_RS02315	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
A8704_RS02345	COG0827	DNA restriction-modification system
A8704_RS02350	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
A8704_RS02355	COG1113	amino acid transport
A8704_RS02365	COG0737	Belongs to the 5'-nucleotidase family
A8704_RS02370	COG4470	Protein conserved in bacteria
A8704_RS02375	COG0647	UMP catabolic process
A8704_RS02385	COG0586	Pfam SNARE associated Golgi protein
A8704_RS02395	COG1098	S1 RNA binding domain
A8704_RS02535	COG1234	tRNA 3'-trailer cleavage
A8704_RS02540	COG1393	Belongs to the ArsC family
A8704_RS02545	COG4862	establishment of competence for transformation
A8704_RS02555	COG1164	Oligoendopeptidase f
A8704_RS02565	COG2357	RelA SpoT domain protein
A8704_RS02570	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
A8704_RS02575	COG0564	pseudouridine synthase activity
A8704_RS02580	COG3142	Participates in the control of copper homeostasis
A8704_RS02585	COG2706	6-phosphogluconolactonase activity
A8704_RS02595	COG0628	permease
A8704_RS02600	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
A8704_RS02610	COG1114	Component of the transport system for branched-chain amino acids
A8704_RS02620	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
A8704_RS02625	COG1674	ftsk spoiiie
A8704_RS02640	COG2001	Belongs to the MraZ family
A8704_RS02645	COG0275	rRNA processing
A8704_RS02655	COG0768	penicillin binding
A8704_RS02660	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
A8704_RS02665	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
A8704_RS02670	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
A8704_RS02675	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
A8704_RS02690	COG1799	cell septum assembly
A8704_RS02695	COG0762	integral membrane protein
A8704_RS02705	COG3599	regulation of cell shape
A8704_RS02710	COG2826	transposase and inactivated derivatives, IS30 family
A8704_RS02715	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
A8704_RS02720	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
A8704_RS02725	COG0494	nUDIX hydrolase
A8704_RS02735	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
A8704_RS02740	COG1104	cysteine desulfurase activity
A8704_RS02750	COG0482	sulfurtransferase activity
A8704_RS02755	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
A8704_RS02760	COG0569	domain protein
A8704_RS02790	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
A8704_RS02795	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
A8704_RS02800	COG3584	3D domain protein
A8704_RS02800	COG1388	LysM domain
A8704_RS02810	COG1597	lipid kinase activity
A8704_RS02815	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
A8704_RS02820	COG5503	Protein of unknown function (DUF1447)
A8704_RS02830	COG0242	peptide deformylase activity
A8704_RS02855	COG0039	L-malate dehydrogenase activity
A8704_RS02860	COG4476	Belongs to the UPF0223 family
A8704_RS02865	COG0483	inositol monophosphate 1-phosphatase activity
A8704_RS02870	COG1217	gtp-binding protein TYPA
A8704_RS02895	COG0772	Belongs to the SEDS family
A8704_RS02900	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
A8704_RS02905	COG4471	UPF0298 protein
A8704_RS02910	COG0742	ribosomal rna small subunit methyltransferase
A8704_RS02915	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
A8704_RS02920	COG3480	Lon protease (S16) C-terminal proteolytic domain
A8704_RS02925	COG1596	polysaccharide export
A8704_RS02925	COG1555	photosystem II stabilization
A8704_RS02930	COG2131	deaminase
A8704_RS02940	COG1466	dna polymerase III delta subunit
A8704_RS02945	COG0268	Binds directly to 16S ribosomal RNA
A8704_RS02950	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
A8704_RS02975	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
A8704_RS02980	COG0544	peptidyl-prolyl cis-trans isomerase activity
A8704_RS02985	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
A8704_RS02990	COG0218	Necessary for normal cell division and for the maintenance of normal septation
A8704_RS03005	COG0765	amino acid transport
A8704_RS03010	COG1126	abc transporter atp-binding protein
A8704_RS03015	COG0322	excinuclease ABC activity
A8704_RS03025	COG0489	protein tyrosine kinase activity
A8704_RS03035	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
A8704_RS03040	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
A8704_RS03070	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
A8704_RS03075	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
A8704_RS03075	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
A8704_RS03075	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
A8704_RS03080	COG1105	Belongs to the carbohydrate kinase PfkB family
A8704_RS03085	COG1349	DNA-binding transcription factor activity
A8704_RS03090	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
A8704_RS03100	COG1234	tRNA 3'-trailer cleavage
A8704_RS03105	COG0300	oxidoreductase activity
A8704_RS03110	COG5416	Lipopolysaccharide assembly protein A domain
A8704_RS03115	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
A8704_RS03115	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
A8704_RS03120	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
A8704_RS03135	COG0393	Putative heavy-metal-binding
A8704_RS03190	COG1396	sequence-specific DNA binding
A8704_RS03270	COG0629	single-stranded DNA binding
A8704_RS03355	COG0740	serine-type endopeptidase activity
A8704_RS03460	COG0772	Belongs to the SEDS family
A8704_RS03470	COG1116	anion transmembrane transporter activity
A8704_RS03485	COG0463	Glycosyl transferase, family 2
A8704_RS03500	COG3425	synthase
A8704_RS03510	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
A8704_RS03515	COG4224	UPF0291 protein
A8704_RS03520	COG3763	UPF0154 protein
A8704_RS03525	COG0204	Acyl-transferase
A8704_RS03530	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
A8704_RS03535	COG2827	Endonuclease containing a URI domain
A8704_RS03540	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
A8704_RS03550	COG0052	Belongs to the universal ribosomal protein uS2 family
A8704_RS03555	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
A8704_RS03560	COG0528	UMP kinase activity
A8704_RS03565	COG0233	cytoplasmic translational termination
A8704_RS03570	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
A8704_RS03575	COG4589	Belongs to the CDS family
A8704_RS03580	COG0750	zinc metalloprotease
A8704_RS03585	COG0442	prolyl-tRNA aminoacylation
A8704_RS03590	COG2176	DNA-directed DNA polymerase activity
A8704_RS03595	COG0779	Required for maturation of 30S ribosomal subunits
A8704_RS03600	COG0195	Participates in both transcription termination and antitermination
A8704_RS03605	COG2740	Nucleic-acid-binding protein implicated in transcription termination
A8704_RS03615	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
A8704_RS03620	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
A8704_RS03625	COG0738	Major facilitator superfamily
A8704_RS03630	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
A8704_RS03640	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
A8704_RS03645	COG0287	Prephenate dehydrogenase
A8704_RS03650	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
A8704_RS03655	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
A8704_RS03660	COG0196	riboflavin kinase activity
A8704_RS03665	COG3527	Alpha-acetolactate decarboxylase
A8704_RS03670	COG1420	regulation of RNA biosynthetic process
A8704_RS03675	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
A8704_RS03680	COG0443	Heat shock 70 kDa protein
A8704_RS03685	COG0484	heat shock protein binding
A8704_RS03690	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
A8704_RS03700	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
A8704_RS03705	COG1696	Membrane protein involved in D-alanine export
A8704_RS03710	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
A8704_RS03715	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
A8704_RS03720	COG0481	GTPase activity
A8704_RS03725	COG0582	viral genome integration into host DNA
A8704_RS03760	COG2094	Belongs to the DNA glycosylase MPG family
A8704_RS03765	COG2264	protein methyltransferase activity
A8704_RS03770	COG1385	rRNA (uridine-N3-)-methyltransferase activity
A8704_RS03780	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
A8704_RS03785	COG1490	D-aminoacyl-tRNA deacylase activity
A8704_RS03790	COG0546	phosphoglycolate phosphatase activity
A8704_RS03795	COG3001	Fructosamine kinase
A8704_RS03800	COG0860	N-Acetylmuramoyl-L-alanine amidase
A8704_RS03800	COG3103	Sh3 type 3 domain protein
A8704_RS03800	COG4991	sh3 domain protein
A8704_RS03805	COG0124	histidyl-tRNA synthetase
A8704_RS03810	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
A8704_RS03820	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
A8704_RS03830	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
A8704_RS03840	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
A8704_RS03845	COG0828	Belongs to the bacterial ribosomal protein bS21 family
A8704_RS03850	COG1610	YqeY-like protein
A8704_RS03855	COG1702	phosphate starvation-inducible protein PhoH
A8704_RS03860	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
A8704_RS03865	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
A8704_RS03870	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
A8704_RS03875	COG1381	Involved in DNA repair and RecF pathway recombination
A8704_RS03880	COG0752	glycyl-tRNA synthetase alpha subunit
A8704_RS03885	COG0751	glycine-tRNA ligase activity
A8704_RS03890	COG0358	DNA primase activity
A8704_RS03895	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
A8704_RS03900	COG1725	Transcriptional regulator
A8704_RS03905	COG2826	transposase and inactivated derivatives, IS30 family
A8704_RS03910	COG1131	(ABC) transporter
A8704_RS03930	COG1131	(ABC) transporter
A8704_RS03950	COG0519	Catalyzes the synthesis of GMP from XMP
A8704_RS03955	COG1131	(ABC) transporter
A8704_RS03965	COG4585	Histidine kinase
A8704_RS03970	COG2197	response regulator
A8704_RS03975	COG0446	pyridine nucleotide-disulphide oxidoreductase
A8704_RS03985	COG0604	alcohol dehydrogenase
A8704_RS03990	COG0583	DNA-binding transcription factor activity
A8704_RS04020	COG0546	phosphoglycolate phosphatase activity
A8704_RS04080	COG1393	Belongs to the ArsC family
A8704_RS04090	COG1349	DNA-binding transcription factor activity
A8704_RS04095	COG0446	pyridine nucleotide-disulphide oxidoreductase
A8704_RS04100	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
A8704_RS04110	COG0477	Major facilitator Superfamily
A8704_RS04115	COG0148	phosphopyruvate hydratase activity
A8704_RS04120	COG2217	Heavy metal translocating P-type atpase
A8704_RS04140	COG1846	Transcriptional regulator
A8704_RS04150	COG0574	Belongs to the PEP-utilizing enzyme family
A8704_RS04150	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
A8704_RS04175	COG2384	SAM-dependent methyltransferase
A8704_RS04180	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
A8704_RS04190	COG0542	response to heat
A8704_RS04200	COG0587	DNA-directed DNA polymerase activity
A8704_RS04205	COG0205	6-phosphofructokinase activity
A8704_RS04220	COG2996	Protein conserved in bacteria
A8704_RS04225	COG4974	Belongs to the 'phage' integrase family
A8704_RS04235	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
A8704_RS04240	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
A8704_RS04245	COG1187	pseudouridine synthase activity
A8704_RS04250	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
A8704_RS04260	COG0514	ATP-dependent DNA helicase (RecQ)
A8704_RS04270	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
A8704_RS04275	COG0539	negative regulation of cytoplasmic translation
A8704_RS04280	COG1160	GTP binding
A8704_RS04290	COG0457	Tetratricopeptide repeat
A8704_RS04295	COG0561	phosphatase activity
A8704_RS04300	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
A8704_RS04305	COG0617	tRNA 3'-terminal CCA addition
A8704_RS04315	COG0488	(ABC) transporter
A8704_RS04320	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
A8704_RS04325	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
A8704_RS04330	COG1307	EDD domain protein, DegV family
A8704_RS04335	COG2755	lipolytic protein G-D-S-L family
A8704_RS04340	COG4698	Protein conserved in bacteria
A8704_RS04345	COG4479	Belongs to the UPF0346 family
A8704_RS04350	COG3409	Peptidoglycan-binding domain 1 protein
A8704_RS04350	COG0793	Belongs to the peptidase S41A family
A8704_RS04355	COG2814	Major facilitator Superfamily
A8704_RS04375	COG0583	DNA-binding transcription factor activity
A8704_RS04380	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
A8704_RS04385	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
A8704_RS04390	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
A8704_RS04395	COG0758	DNA mediated transformation
A8704_RS04400	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
A8704_RS04405	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
A8704_RS04410	COG4974	Belongs to the 'phage' integrase family
A8704_RS04415	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
A8704_RS04420	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
A8704_RS04430	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
A8704_RS04435	COG0187	DNA topoisomerase II activity
A8704_RS04445	COG0583	DNA-binding transcription factor activity
A8704_RS04450	COG1227	inorganic diphosphatase activity
A8704_RS04455	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
A8704_RS04495	COG1846	Transcriptional regulator
A8704_RS04510	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
A8704_RS04520	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
A8704_RS04530	COG1620	l-lactate permease
A8704_RS04545	COG1113	amino acid transport
A8704_RS04600	COG1307	EDD domain protein, DegV family
A8704_RS04610	COG1293	RNA-binding protein homologous to eukaryotic snRNP
A8704_RS04615	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
A8704_RS04620	COG1131	(ABC) transporter
A8704_RS04645	COG5646	InterPro IPR014922
A8704_RS04655	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
A8704_RS04660	COG0505	Belongs to the CarA family
A8704_RS04665	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
A8704_RS04670	COG0564	pseudouridine synthase activity
A8704_RS04675	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
A8704_RS04680	COG2759	Belongs to the formate--tetrahydrofolate ligase family
A8704_RS04695	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
A8704_RS04720	COG1619	proteins homologs of microcin C7 resistance protein MccF
A8704_RS04740	COG1216	Glycosyl transferase, family 2
A8704_RS04750	COG1073	alpha beta
A8704_RS04755	COG0477	Major facilitator Superfamily
A8704_RS04765	COG0116	Belongs to the methyltransferase superfamily
A8704_RS04775	COG3599	regulation of cell shape
A8704_RS04780	COG4474	Belongs to the UPF0398 family
A8704_RS04785	COG3331	DNA recombination
A8704_RS04805	COG1840	ABC-type Fe3 transport system, periplasmic component
A8704_RS04810	COG1177	transmembrane transport
A8704_RS04820	COG1464	Belongs to the NlpA lipoprotein family
A8704_RS04825	COG2011	ABC-type metal ion transport system permease component
A8704_RS04830	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
A8704_RS04845	COG0017	Asparaginyl-tRNA synthetase
A8704_RS04860	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
A8704_RS04860	COG1199	ATP-dependent helicase activity
A8704_RS04880	COG1304	FMN binding
A8704_RS04885	COG2017	converts alpha-aldose to the beta-anomer
A8704_RS04905	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
A8704_RS04905	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
A8704_RS04910	COG0561	phosphatase activity
A8704_RS04915	COG0531	amino acid
A8704_RS04950	COG1942	4-Oxalocrotonate Tautomerase
A8704_RS04965	COG3237	CsbD-like
A8704_RS04970	COG2261	transglycosylase associated protein
A8704_RS04985	COG3293	Transposase
A8704_RS04990	COG1597	lipid kinase activity
A8704_RS04995	COG3152	Membrane
A8704_RS05005	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
A8704_RS05015	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
A8704_RS05020	COG3397	chitin binding
A8704_RS05035	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
A8704_RS05055	COG0477	Major facilitator Superfamily
A8704_RS05060	COG1162	GTPase activity
A8704_RS05065	COG1607	acyl-coa hydrolase
A8704_RS05070	COG0583	DNA-binding transcription factor activity
A8704_RS05075	COG1811	Na channel or pump
A8704_RS05085	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
A8704_RS05100	COG0439	Biotin carboxylase
A8704_RS05115	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
A8704_RS05120	COG1028	Short-chain dehydrogenase reductase Sdr
A8704_RS05125	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
A8704_RS05130	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
A8704_RS05135	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
A8704_RS05140	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
A8704_RS05150	COG0300	oxidoreductase activity
A8704_RS05160	COG1063	alcohol dehydrogenase
A8704_RS05165	COG1473	amidohydrolase
A8704_RS05180	COG3293	Transposase
A8704_RS05185	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
A8704_RS05200	COG0159	tryptophan synthase activity
A8704_RS05205	COG0133	tryptophan synthase activity
A8704_RS05210	COG0135	phosphoribosylanthranilate isomerase activity
A8704_RS05220	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
A8704_RS05225	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
A8704_RS05225	COG0512	Glutamine amidotransferase of anthranilate synthase
A8704_RS05240	COG1131	(ABC) transporter
A8704_RS05260	COG0335	large ribosomal subunit rRNA binding
A8704_RS05265	COG0336	Belongs to the RNA methyltransferase TrmD family
A8704_RS05270	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
A8704_RS05275	COG1837	Belongs to the UPF0109 family
A8704_RS05280	COG0228	four-way junction DNA binding
A8704_RS05285	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
A8704_RS05290	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
A8704_RS05295	COG0552	protein localization to endoplasmic reticulum
A8704_RS05300	COG1196	nuclear chromosome segregation
A8704_RS05305	COG0571	ribonuclease III activity
A8704_RS05310	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
A8704_RS05315	COG0416	fatty acid biosynthetic process
A8704_RS05320	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
A8704_RS05325	COG1461	Dihydroxyacetone kinase
A8704_RS05330	COG1302	Protein conserved in bacteria
A8704_RS05335	COG0227	Belongs to the bacterial ribosomal protein bL28 family
A8704_RS05340	COG1564	THIamine pyrophosphokinase
A8704_RS05345	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
A8704_RS05350	COG1162	GTPase activity
A8704_RS05355	COG0515	serine threonine protein kinase
A8704_RS05355	COG2815	serine threonine protein kinase
A8704_RS05360	COG0631	protein serine/threonine phosphatase activity
A8704_RS05365	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
A8704_RS05365	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
A8704_RS05370	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
A8704_RS05375	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
A8704_RS05380	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
A8704_RS05385	COG1758	RNA polymerase activity
A8704_RS05390	COG0194	GDP metabolic process
A8704_RS05405	COG1732	Glycine betaine
A8704_RS05420	COG0497	DNA recombination
A8704_RS05425	COG1438	arginine binding
A8704_RS05430	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
A8704_RS05435	COG0142	geranyltranstransferase activity
A8704_RS05440	COG1722	exodeoxyribonuclease VII activity
A8704_RS05445	COG1570	exodeoxyribonuclease VII activity
A8704_RS05450	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
A8704_RS05455	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
A8704_RS05460	COG1302	Protein conserved in bacteria
A8704_RS05465	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
A8704_RS05470	COG0006	proline dipeptidase activity
A8704_RS05475	COG0211	Belongs to the bacterial ribosomal protein bL27 family
A8704_RS05485	COG0261	This protein binds to 23S rRNA in the presence of protein L20
A8704_RS05530	COG0789	Transcriptional regulator
A8704_RS05535	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
A8704_RS05540	COG0584	glycerophosphoryl diester phosphodiesterase
A8704_RS05560	COG1940	carbohydrate kinase activity
A8704_RS05570	COG0705	Rhomboid family
A8704_RS05570	COG0457	Tetratricopeptide repeat
A8704_RS05575	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
A8704_RS05580	COG0768	penicillin binding
A8704_RS05590	COG4841	protein insertion into membrane
A8704_RS05605	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
A8704_RS05610	COG0572	uridine kinase
A8704_RS05615	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
A8704_RS05620	COG0072	phenylalanine-tRNA ligase activity
A8704_RS05620	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
A8704_RS05625	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
A8704_RS05630	COG1733	regulation of RNA biosynthetic process
A8704_RS05640	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
A8704_RS05645	COG1254	Belongs to the acylphosphatase family
A8704_RS05650	COG0706	membrane insertase activity
A8704_RS05665	COG0419	ATPase involved in DNA repair
A8704_RS05675	COG5002	protein histidine kinase activity
A8704_RS05680	COG0745	RESPONSE REGULATOR receiver
A8704_RS05685	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
A8704_RS05690	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
A8704_RS05710	COG1323	Belongs to the UPF0348 family
A8704_RS05715	COG2226	methyltransferase
A8704_RS05720	COG0799	negative regulation of ribosome biogenesis
A8704_RS05725	COG1713	HD superfamily hydrolase involved in NAD metabolism
A8704_RS05730	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
A8704_RS05735	COG1534	Rna-binding protein
A8704_RS05740	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
A8704_RS05755	COG1215	transferase activity, transferring glycosyl groups
A8704_RS05765	COG1733	regulation of RNA biosynthetic process
A8704_RS05770	COG0604	alcohol dehydrogenase
A8704_RS05775	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
A8704_RS05785	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
A8704_RS05790	COG0291	Belongs to the bacterial ribosomal protein bL35 family
A8704_RS05795	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
A8704_RS05800	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
A8704_RS05805	COG1484	DNA-dependent DNA replication
A8704_RS05810	COG3611	Membrane attachment protein
A8704_RS05815	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
A8704_RS05820	COG0237	dephospho-CoA kinase activity
A8704_RS05825	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
A8704_RS05830	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
A8704_RS05830	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
A8704_RS05845	COG2151	metal-sulfur cluster biosynthetic enzyme
A8704_RS05850	COG0719	Fe-S assembly protein
A8704_RS05860	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
A8704_RS05865	COG0719	Fe-S assembly protein
A8704_RS05885	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
A8704_RS05890	COG1674	ftsk spoiiie
A8704_RS05895	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
A8704_RS05905	COG0220	tRNA (guanine-N7-)-methyltransferase activity
A8704_RS05910	COG0510	thiamine kinase activity
A8704_RS05915	COG4473	ABC transporter
A8704_RS05920	COG1131	(ABC) transporter
A8704_RS05925	COG0537	adenosine 5'-monophosphoramidase activity
A8704_RS05935	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
A8704_RS05970	COG0446	pyridine nucleotide-disulphide oxidoreductase
A8704_RS05980	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
A8704_RS05995	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
A8704_RS06000	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
A8704_RS06000	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
A8704_RS06005	COG0307	riboflavin synthase, alpha
A8704_RS06010	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
A8704_RS06010	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
A8704_RS06030	COG0463	Glycosyl transferase, family 2
A8704_RS06045	COG3976	FMN-binding domain protein
A8704_RS06045	COG1053	succinate dehydrogenase
A8704_RS06045	COG0431	NADPH-dependent FMN reductase
A8704_RS06055	COG0583	DNA-binding transcription factor activity
A8704_RS06075	COG3481	metal-dependent phosphohydrolase, HD sub domain
A8704_RS06080	COG4717	serine-type aminopeptidase activity
A8704_RS06085	COG0420	3'-5' exonuclease activity
A8704_RS06090	COG3679	Belongs to the UPF0342 family
A8704_RS06095	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
A8704_RS06100	COG1438	arginine binding
A8704_RS06105	COG0436	Aminotransferase
A8704_RS06115	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
A8704_RS06120	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
A8704_RS06125	COG1376	ErfK ybiS ycfS ynhG family protein
A8704_RS06135	COG2723	6-phospho-beta-galactosidase activity
A8704_RS06140	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
A8704_RS06145	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
A8704_RS06150	COG1447	Phosphotransferase system cellobiose-specific component IIA
A8704_RS06170	COG0577	efflux transmembrane transporter activity
A8704_RS06170	COG1136	(ABC) transporter
A8704_RS06180	COG0018	arginyl-trna synthetase
A8704_RS06185	COG2153	protein acetylation
A8704_RS06205	COG0534	Mate efflux family protein
A8704_RS06215	COG3293	Transposase
A8704_RS06220	COG3273	potassium ion transport
A8704_RS06220	COG0471	metal ion transport
A8704_RS06230	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
A8704_RS06235	COG0529	Catalyzes the synthesis of activated sulfate
A8704_RS06240	COG2046	Belongs to the sulfate adenylyltransferase family
A8704_RS06250	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
A8704_RS06255	COG0646	methionine synthase
A8704_RS06255	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
A8704_RS06290	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
A8704_RS06305	COG1846	Transcriptional regulator
A8704_RS06325	COG3279	Response regulator of the LytR AlgR family
A8704_RS06340	COG0561	phosphatase activity
A8704_RS06345	COG0697	spore germination
A8704_RS06355	COG0789	Transcriptional regulator
A8704_RS06360	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
A8704_RS06370	COG3279	Response regulator of the LytR AlgR family
A8704_RS06390	COG1511	domain protein
A8704_RS06390	COG1511	domain protein
A8704_RS06395	COG1970	mechanosensitive ion channel activity
A8704_RS06400	COG1428	Deoxynucleoside kinase
A8704_RS06405	COG0584	glycerophosphoryl diester phosphodiesterase
A8704_RS06415	COG0395	ABC-type sugar transport system, permease component
A8704_RS06420	COG1175	transmembrane transport
A8704_RS06425	COG3842	ATPase activity
A8704_RS06435	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
A8704_RS06440	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
A8704_RS06445	COG1187	pseudouridine synthase activity
A8704_RS06450	COG2244	polysaccharide biosynthetic process
A8704_RS06455	COG0495	leucyl-tRNA aminoacylation
A8704_RS06465	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
A8704_RS06480	COG0438	transferase activity, transferring glycosyl groups
A8704_RS06500	COG0477	Major facilitator Superfamily
A8704_RS06505	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
A8704_RS06515	COG0438	transferase activity, transferring glycosyl groups
A8704_RS06520	COG2040	homocysteine
A8704_RS06525	COG0833	amino acid
A8704_RS06530	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
A8704_RS06540	COG1940	carbohydrate kinase activity
A8704_RS06555	COG2207	Transcriptional regulator
A8704_RS06555	COG4753	response regulator
A8704_RS06560	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
A8704_RS06580	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
A8704_RS06665	COG1368	sulfuric ester hydrolase activity
A8704_RS06670	COG4703	Protein of unknown function (DUF1797)
A8704_RS06675	COG0436	Aminotransferase
A8704_RS06680	COG1686	Belongs to the peptidase S11 family
A8704_RS06690	COG0438	transferase activity, transferring glycosyl groups
A8704_RS06695	COG0438	transferase activity, transferring glycosyl groups
A8704_RS06715	COG0542	response to heat
A8704_RS06720	COG0582	viral genome integration into host DNA
A8704_RS06730	COG4608	Belongs to the ABC transporter superfamily
A8704_RS06735	COG0444	Belongs to the ABC transporter superfamily
A8704_RS06740	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
A8704_RS06745	COG0601	transmembrane transport
A8704_RS06750	COG4166	transmembrane transport
A8704_RS06780	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
A8704_RS06785	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
A8704_RS06790	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
A8704_RS06795	COG1070	Carbohydrate kinase
A8704_RS06800	COG2610	gluconate transmembrane transporter activity
A8704_RS06805	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
A8704_RS06810	COG0628	permease
A8704_RS06835	COG3557	Belongs to the UPF0374 family
A8704_RS06840	COG2137	regulation of response to DNA damage stimulus
A8704_RS06915	COG0562	UDP-galactopyranose mutase
A8704_RS06935	COG3293	Transposase
A8704_RS06955	COG3328	transposase activity
A8704_RS06965	COG0562	UDP-galactopyranose mutase
A8704_RS06970	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
A8704_RS06980	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
A8704_RS06990	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
A8704_RS07015	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
A8704_RS07030	COG0513	Belongs to the DEAD box helicase family
A8704_RS07035	COG0673	inositol 2-dehydrogenase activity
A8704_RS07040	COG1278	Cold shock
A8704_RS07055	COG1737	Transcriptional regulator
A8704_RS07065	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
A8704_RS07080	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
A8704_RS07085	COG1597	lipid kinase activity
A8704_RS07090	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
A8704_RS07095	COG0154	amidase activity
A8704_RS07100	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
A8704_RS07105	COG4851	CamS sex pheromone cAM373 precursor
A8704_RS07110	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
A8704_RS07120	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
A8704_RS07125	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
A8704_RS07130	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
A8704_RS07135	COG1705	Flagellar rod assembly protein muramidase FlgJ
A8704_RS07150	COG0142	geranyltranstransferase activity
A8704_RS07165	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
A8704_RS07170	COG4988	ABC transporter
A8704_RS07175	COG1294	oxidase, subunit
A8704_RS07180	COG1271	oxidase subunit
A8704_RS07190	COG4684	Psort location CytoplasmicMembrane, score
A8704_RS07195	COG0531	amino acid
A8704_RS07205	COG0281	malic enzyme
A8704_RS07210	COG0583	DNA-binding transcription factor activity
A8704_RS07215	COG0583	DNA-binding transcription factor activity
A8704_RS07225	COG1053	succinate dehydrogenase
A8704_RS07230	COG0114	fumarate hydratase activity
A8704_RS07260	COG2826	transposase and inactivated derivatives, IS30 family
A8704_RS07275	COG3052	prosthetic group binding
A8704_RS07295	COG0471	metal ion transport
A8704_RS07300	COG0039	L-malate dehydrogenase activity
A8704_RS07310	COG0803	Belongs to the bacterial solute-binding protein 9 family
A8704_RS07315	COG1108	ABC-type Mn2 Zn2 transport systems permease components
A8704_RS07320	COG1121	(ABC) transporter
A8704_RS07325	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
A8704_RS07330	COG4977	sequence-specific DNA binding
A8704_RS07330	COG1917	Cupin 2, conserved barrel domain protein
A8704_RS07340	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
A8704_RS07345	COG2151	metal-sulfur cluster biosynthetic enzyme
A8704_RS07350	COG0471	metal ion transport
A8704_RS07355	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
A8704_RS07360	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
A8704_RS07365	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
A8704_RS07390	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
A8704_RS07395	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
A8704_RS07400	COG0101	tRNA pseudouridine synthase activity
A8704_RS07410	COG1122	ATPase activity
A8704_RS07415	COG1122	ATPase activity
A8704_RS07425	COG4939	FMN-binding domain protein
A8704_RS07450	COG0203	ribosomal protein L17
A8704_RS07455	COG0202	RNA polymerase activity
A8704_RS07460	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
A8704_RS07465	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
A8704_RS07470	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
A8704_RS07475	COG0563	adenylate kinase activity
A8704_RS07485	COG0200	Binds to the 23S rRNA
A8704_RS07490	COG1841	ribosomal large subunit assembly
A8704_RS07495	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
A8704_RS07500	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
A8704_RS07505	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
A8704_RS07510	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
A8704_RS07515	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
A8704_RS07520	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
A8704_RS07525	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
A8704_RS07530	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
A8704_RS07535	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
A8704_RS07540	COG0255	Belongs to the universal ribosomal protein uL29 family
A8704_RS07545	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
A8704_RS07550	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
A8704_RS07555	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
A8704_RS07560	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
A8704_RS07565	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
A8704_RS07570	COG0089	rRNA binding
A8704_RS07575	COG0088	Forms part of the polypeptide exit tunnel
A8704_RS07580	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
A8704_RS07585	COG0051	transcription antitermination factor activity, RNA binding
A8704_RS07590	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
A8704_RS07595	COG0049	tRNA binding
A8704_RS07600	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
A8704_RS07610	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
A8704_RS07615	COG0085	RNA polymerase activity
A8704_RS07625	COG0542	response to heat
A8704_RS07630	COG4463	regulation of RNA biosynthetic process
A8704_RS07670	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
A8704_RS07675	COG1428	Deoxynucleoside kinase
A8704_RS07685	COG0833	amino acid
A8704_RS07690	COG0028	Belongs to the TPP enzyme family
A8704_RS07695	COG1959	2 iron, 2 sulfur cluster binding
A8704_RS07715	COG1316	TRANSCRIPTIONal
A8704_RS07725	COG2966	Psort location CytoplasmicMembrane, score
A8704_RS07730	COG1278	Cold shock
A8704_RS07750	COG2814	Major facilitator Superfamily
A8704_RS07780	COG0367	asparagine synthase
A8704_RS07785	COG0527	aspartate kinase activity
A8704_RS07790	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
A8704_RS07815	COG0583	DNA-binding transcription factor activity
A8704_RS07820	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
A8704_RS07830	COG2610	gluconate transmembrane transporter activity
A8704_RS07835	COG4948	Mandelate Racemase Muconate Lactonizing
A8704_RS07840	COG2706	6-phosphogluconolactonase activity
A8704_RS07875	COG0640	Transcriptional regulator
A8704_RS07880	COG0564	pseudouridine synthase activity
A8704_RS07885	COG0514	ATP-dependent DNA helicase (RecQ)
A8704_RS07905	COG4690	dipeptidase activity
A8704_RS07910	COG2502	aspartate--ammonia ligase
A8704_RS07915	COG0017	Asparaginyl-tRNA synthetase
A8704_RS07920	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
A8704_RS07930	COG1053	succinate dehydrogenase
A8704_RS07935	COG0583	DNA-binding transcription factor activity
A8704_RS07955	COG4932	domain protein
A8704_RS07955	COG4886	Leucine-rich repeat (LRR) protein
A8704_RS07970	COG3293	Transposase
A8704_RS07990	COG3293	Transposase
A8704_RS08015	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
A8704_RS08020	COG0308	aminopeptidase N
A8704_RS08050	COG1302	Protein conserved in bacteria
A8704_RS08065	COG2261	transglycosylase associated protein
A8704_RS08070	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
A8704_RS08070	COG2755	lipolytic protein G-D-S-L family
A8704_RS08085	COG2814	Major facilitator Superfamily
A8704_RS08090	COG2801	Transposase and inactivated derivatives
A8704_RS08100	COG1733	regulation of RNA biosynthetic process
A8704_RS08105	COG1266	CAAX protease self-immunity
A8704_RS08110	COG1396	sequence-specific DNA binding
A8704_RS08130	COG3293	Transposase
A8704_RS08160	COG0464	growth
A8704_RS08185	COG0519	Catalyzes the synthesis of GMP from XMP
A8704_RS08185	COG0518	GMP synthase (glutamine-hydrolyzing) activity
A8704_RS08190	COG1072	(Pantothenic acid kinase))
A8704_RS08200	COG3973	AAA domain
A8704_RS08205	COG0586	Pfam SNARE associated Golgi protein
A8704_RS08210	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
A8704_RS08210	COG0456	acetyltransferase
A8704_RS08215	COG0475	glutathione-regulated potassium exporter activity
A8704_RS08215	COG0569	domain protein
A8704_RS08220	COG0588	phosphoglycerate mutase activity
A8704_RS08235	COG2076	Multidrug Resistance protein
A8704_RS08245	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
A8704_RS08275	COG1846	Transcriptional regulator
A8704_RS08280	COG0531	amino acid
A8704_RS08285	COG3394	polysaccharide catabolic process
A8704_RS08300	COG1263	PTS System
A8704_RS08300	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
A8704_RS08300	COG2190	(PTS) system
A8704_RS08305	COG0765	amino acid transport
A8704_RS08310	COG0765	amino acid transport
A8704_RS08315	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
A8704_RS08330	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
A8704_RS08335	COG0436	Aminotransferase
A8704_RS08340	COG0546	phosphoglycolate phosphatase activity
A8704_RS08355	COG0735	belongs to the Fur family
A8704_RS08360	COG0194	GDP metabolic process
A8704_RS08380	COG0531	amino acid
A8704_RS08395	COG2936	dipeptidyl-peptidase activity
A8704_RS08400	COG2755	lipolytic protein G-D-S-L family
A8704_RS08400	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
A8704_RS08410	COG2267	carboxylic ester hydrolase activity
A8704_RS08415	COG0028	Belongs to the TPP enzyme family
A8704_RS08420	COG0196	riboflavin kinase activity
A8704_RS08425	COG0028	Belongs to the TPP enzyme family
A8704_RS08430	COG2252	PERMEase
A8704_RS08440	COG3475	LICD family
A8704_RS08450	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
A8704_RS08460	COG0477	Major facilitator Superfamily
A8704_RS08475	COG1393	Belongs to the ArsC family
A8704_RS08490	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
A8704_RS08505	COG0778	Nitroreductase
A8704_RS08530	COG0561	phosphatase activity
A8704_RS08540	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
A8704_RS08545	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
A8704_RS08570	COG0025	NhaP-type Na H and K H
A8704_RS08575	COG0812	UDP-N-acetylmuramate dehydrogenase activity
A8704_RS08585	COG0708	Exodeoxyribonuclease III
A8704_RS08600	COG0802	atpase or kinase
A8704_RS08605	COG0280	phosphate acetyltransferase
A8704_RS08610	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
A8704_RS08615	COG0561	phosphatase activity
A8704_RS08625	COG1126	abc transporter atp-binding protein
A8704_RS08630	COG0765	amino acid transport
A8704_RS08640	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
A8704_RS08645	COG0557	exoribonuclease II activity
A8704_RS08655	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
A8704_RS08660	COG0038	chloride channel
A8704_RS08670	COG0148	phosphopyruvate hydratase activity
A8704_RS08675	COG0149	triose-phosphate isomerase activity
A8704_RS08680	COG0126	phosphoglycerate kinase activity
A8704_RS08690	COG2390	Transcriptional regulator
A8704_RS08695	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
A8704_RS08705	COG0740	serine-type endopeptidase activity
A8704_RS08710	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
A8704_RS08720	COG1481	regulation of sporulation
A8704_RS08730	COG1660	Displays ATPase and GTPase activities
A8704_RS08740	COG0165	Argininosuccinate lyase
A8704_RS08745	COG0137	argininosuccinate synthase activity
A8704_RS08750	COG1854	S-ribosylhomocysteine lyase activity
A8704_RS08755	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
A8704_RS08760	COG0556	nucleotide-excision repair
A8704_RS08770	COG2814	Major facilitator Superfamily
A8704_RS08780	COG0446	pyridine nucleotide-disulphide oxidoreductase
A8704_RS08790	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
A8704_RS08800	COG2323	membrane
A8704_RS08805	COG0492	ferredoxin-NADP+ reductase activity
A8704_RS08810	COG0446	pyridine nucleotide-disulphide oxidoreductase
A8704_RS08820	COG1210	Utp--glucose-1-phosphate uridylyltransferase
A8704_RS08825	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
A8704_RS08830	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
A8704_RS08835	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
A8704_RS08840	COG1950	PFAM Membrane protein of
A8704_RS08845	COG1983	PspC domain protein
A8704_RS08850	COG0704	Plays a role in the regulation of phosphate uptake
A8704_RS08855	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
A8704_RS08860	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
A8704_RS08865	COG0581	inorganic phosphate transmembrane transporter activity
A8704_RS08870	COG0573	inorganic phosphate transmembrane transporter activity
A8704_RS08875	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
A8704_RS08880	COG5002	protein histidine kinase activity
A8704_RS08885	COG0745	RESPONSE REGULATOR receiver
A8704_RS08895	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
A8704_RS08900	COG0653	protein targeting
A8704_RS08915	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
A8704_RS08920	COG1739	Uncharacterized protein family UPF0029
A8704_RS08925	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
A8704_RS08930	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
A8704_RS08935	COG0531	amino acid
A8704_RS08940	COG0459	protein refolding
A8704_RS08945	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
A8704_RS08955	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
A8704_RS08960	COG0488	(ABC) transporter
A8704_RS08965	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
A8704_RS08970	COG0456	acetyltransferase
A8704_RS08975	COG0456	acetyltransferase
A8704_RS08980	COG1214	PFAM Peptidase M22, glycoprotease
A8704_RS08990	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
A8704_RS09000	COG3639	organic phosphonate transmembrane transporter activity
A8704_RS09005	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
A8704_RS09010	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
A8704_RS09015	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
A8704_RS09030	COG4467	Involved in initiation control of chromosome replication
A8704_RS09035	COG0470	DNA polymerase III
A8704_RS09040	COG3870	Protein conserved in bacteria
A8704_RS09045	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
A8704_RS09055	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
A8704_RS09060	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
A8704_RS09065	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
A8704_RS09080	COG2813	Specifically methylates the guanine in position
A8704_RS09085	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
A8704_RS09090	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
A8704_RS09100	COG1611	Belongs to the LOG family
A8704_RS09120	COG0222	ribosome binding
A8704_RS09125	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
A8704_RS09130	COG0081	regulation of translation
A8704_RS09135	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
A8704_RS09145	COG0250	Participates in transcription elongation, termination and antitermination
A8704_RS09155	COG0267	Belongs to the bacterial ribosomal protein bL33 family
A8704_RS09170	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
A8704_RS09175	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
A8704_RS09180	COG0215	cysteine-tRNA ligase activity
A8704_RS09185	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
A8704_RS09190	COG4956	integral membrane protein (PIN domain superfamily)
A8704_RS09200	COG0756	dUTP diphosphatase activity
A8704_RS09210	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
A8704_RS09225	COG0588	phosphoglycerate mutase activity
A8704_RS09230	COG0697	spore germination
A8704_RS09240	COG1316	TRANSCRIPTIONal
A8704_RS09245	COG0825	malonyl-CoA metabolic process
A8704_RS09265	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
A8704_RS09270	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
A8704_RS09270	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
A8704_RS09275	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
A8704_RS09275	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
A8704_RS09280	COG3933	PFAM sigma-54 factor interaction domain-containing protein
A8704_RS09280	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
A8704_RS09290	COG3716	PTS system mannose fructose sorbose family IID component
A8704_RS09295	COG3715	PTS system
A8704_RS09315	COG0083	homoserine kinase activity
A8704_RS09320	COG0460	homoserine dehydrogenase
A8704_RS09325	COG3091	SprT-like family
A8704_RS09330	COG2183	response to ionizing radiation
A8704_RS09345	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
A8704_RS09350	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
A8704_RS09360	COG2188	Transcriptional regulator
A8704_RS09370	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
A8704_RS09420	COG3104	oligopeptide transport
A8704_RS09460	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
A8704_RS09465	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
A8704_RS09470	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
A8704_RS09485	COG0037	tRNA processing
A8704_RS09490	COG1098	S1 RNA binding domain
A8704_RS09500	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
A8704_RS09505	COG2244	polysaccharide biosynthetic process
A8704_RS09510	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
A8704_RS09515	COG0193	aminoacyl-tRNA hydrolase activity
A8704_RS09520	COG0039	L-malate dehydrogenase activity
A8704_RS09535	COG2267	carboxylic ester hydrolase activity
A8704_RS09550	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
A8704_RS09555	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
A8704_RS09560	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
A8704_RS09565	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
A8704_RS09570	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
A8704_RS09575	COG0505	Belongs to the CarA family
A8704_RS09580	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
A8704_RS09600	COG3158	transport of potassium into the cell
A8704_RS09605	COG2337	Toxic component of a toxin-antitoxin (TA) module
A8704_RS09610	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
A8704_RS09615	COG0736	holo-[acyl-carrier-protein] synthase activity
A8704_RS09625	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
A8704_RS09635	COG0501	Belongs to the peptidase M48B family
A8704_RS09640	COG1704	LemA family
A8704_RS09645	COG3764	Sortase (surface protein transpeptidase)
A8704_RS09655	COG0254	rRNA binding
A8704_RS09660	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
A8704_RS09665	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
A8704_RS09685	COG1760	l-serine dehydratase
A8704_RS09690	COG1760	l-serine dehydratase
A8704_RS09695	COG0814	amino acid
A8704_RS09700	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
A8704_RS09705	COG0504	CTP synthase activity
A8704_RS09710	COG3343	RNA polymerase activity
A8704_RS09720	COG0095	Lipoate-protein ligase
A8704_RS09725	COG1078	dGTPase activity
A8704_RS09745	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
A8704_RS09755	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
A8704_RS09760	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
A8704_RS09780	COG1108	ABC-type Mn2 Zn2 transport systems permease components
A8704_RS09780	COG1321	iron dependent repressor
A8704_RS09785	COG1121	(ABC) transporter
A8704_RS09790	COG1073	alpha beta
A8704_RS09795	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
A8704_RS09800	COG4466	Protein conserved in bacteria
A8704_RS09805	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
A8704_RS09810	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
A8704_RS09815	COG0084	hydrolase, TatD family'
A8704_RS09830	COG2814	Major facilitator Superfamily
A8704_RS09835	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
A8704_RS09835	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
A8704_RS09845	COG1801	Protein of unknown function DUF72
A8704_RS09850	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
A8704_RS09865	COG0248	Ppx GppA phosphatase
A8704_RS09870	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
A8704_RS09895	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
A8704_RS09900	COG2188	Transcriptional regulator
A8704_RS09905	COG0180	Tryptophanyl-tRNA synthetase
A8704_RS09910	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
A8704_RS09915	COG3973	AAA domain
A8704_RS09940	COG3328	transposase activity
A8704_RS09955	COG0561	phosphatase activity
A8704_RS09965	COG0561	phosphatase activity
A8704_RS09975	COG0110	maltose O-acetyltransferase activity
A8704_RS10055	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
A8704_RS10065	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
A8704_RS10075	COG1125	glycine betaine transport
A8704_RS10090	COG0300	oxidoreductase activity
A8704_RS10120	COG1881	PFAM PEBP family protein
A8704_RS10125	COG3759	membrane
A8704_RS10135	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
A8704_RS10150	COG2826	transposase and inactivated derivatives, IS30 family
A8704_RS10160	COG0004	ammonium transporteR
A8704_RS10165	COG2814	Major facilitator Superfamily
A8704_RS10180	COG1134	teichoic acid transport
A8704_RS10185	COG1682	transport, permease protein
A8704_RS10195	COG0436	Aminotransferase
A8704_RS10210	COG1268	BioY protein
A8704_RS10245	COG1454	alcohol dehydrogenase
A8704_RS10245	COG1012	belongs to the aldehyde dehydrogenase family
A8704_RS10255	COG1131	(ABC) transporter
A8704_RS10260	COG1725	Transcriptional regulator
A8704_RS10290	COG3842	ATPase activity
A8704_RS10315	COG1252	NADH dehydrogenase
A8704_RS10320	COG1846	Transcriptional regulator
A8704_RS10330	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
A8704_RS10340	COG1199	ATP-dependent helicase activity
A8704_RS10360	COG1388	LysM domain
A8704_RS10360	COG3942	CHAP domain
A8704_RS10365	COG0741	lytic transglycosylase activity
A8704_RS10380	COG1136	(ABC) transporter
A8704_RS10385	COG0577	efflux transmembrane transporter activity
A8704_RS10395	COG2818	Glycosylase
A8704_RS10400	COG1033	growth of symbiont in host cell
A8704_RS10400	COG2409	Drug exporters of the RND superfamily
A8704_RS10400	COG1033	growth of symbiont in host cell
A8704_RS10400	COG2409	Drug exporters of the RND superfamily
A8704_RS10410	COG2357	RelA SpoT domain protein
A8704_RS10420	COG0277	FAD linked oxidase domain protein
A8704_RS10425	COG1316	TRANSCRIPTIONal
A8704_RS10440	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
A8704_RS10445	COG1737	Transcriptional regulator
A8704_RS10455	COG0745	RESPONSE REGULATOR receiver
A8704_RS10460	COG5002	protein histidine kinase activity
A8704_RS10470	COG2814	Major facilitator Superfamily
A8704_RS10490	COG1914	H( )-stimulated, divalent metal cation uptake system
A8704_RS10495	COG1309	transcriptional regulator
A8704_RS10500	COG1959	2 iron, 2 sulfur cluster binding
A8704_RS10510	COG0163	prenyltransferase activity
A8704_RS10515	COG0463	Glycosyl transferase, family 2
A8704_RS10515	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
A8704_RS10520	COG1215	transferase activity, transferring glycosyl groups
A8704_RS10520	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
A8704_RS10525	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
A8704_RS10530	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
A8704_RS10535	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
A8704_RS10545	COG2190	(PTS) system
A8704_RS10545	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
A8704_RS10545	COG1263	PTS System
A8704_RS10555	COG0366	Alpha amylase catalytic
A8704_RS10560	COG2188	Transcriptional regulator
A8704_RS10585	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
A8704_RS10590	COG0626	cystathionine gamma-synthase activity
A8704_RS10595	COG1045	serine acetyltransferase
A8704_RS10600	COG0431	NADPH-dependent FMN reductase
A8704_RS10630	COG3118	belongs to the thioredoxin family
A8704_RS10640	COG0246	Mannitol dehydrogenase
A8704_RS10645	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
A8704_RS10655	COG2213	PTS system mannitol-specific
A8704_RS10680	COG3293	Transposase
A8704_RS10690	COG0363	glucosamine-6-phosphate deaminase activity
A8704_RS10705	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
A8704_RS10715	COG0386	Belongs to the glutathione peroxidase family
A8704_RS10725	COG4172	Belongs to the ABC transporter superfamily
A8704_RS10735	COG0488	(ABC) transporter
A8704_RS10740	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
A8704_RS10745	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
A8704_RS10775	COG0667	Aldo Keto reductase
A8704_RS10780	COG0406	alpha-ribazole phosphatase activity
A8704_RS10785	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
A8704_RS10790	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
A8704_RS10800	COG4166	transmembrane transport
A8704_RS10805	COG4166	transmembrane transport
A8704_RS10830	COG1757	Na H antiporter
A8704_RS10890	COG3842	ATPase activity
A8704_RS10915	COG0366	Alpha amylase catalytic
A8704_RS10920	COG0366	Alpha amylase catalytic
A8704_RS10925	COG1609	Transcriptional regulator
A8704_RS10930	COG1609	Transcriptional regulator
A8704_RS10940	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
A8704_RS10945	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
A8704_RS10960	COG1131	(ABC) transporter
A8704_RS10965	COG1028	Short-chain dehydrogenase reductase Sdr
A8704_RS10990	COG2188	Transcriptional regulator
A8704_RS11000	COG4720	Psort location CytoplasmicMembrane, score
A8704_RS11005	COG1122	ATPase activity
A8704_RS11010	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
A8704_RS11040	COG0667	Aldo Keto reductase
A8704_RS11045	COG0656	L-ascorbic acid biosynthetic process
A8704_RS11050	COG2807	transmembrane transport
A8704_RS11085	COG1983	PspC domain protein
A8704_RS11090	COG0813	purine-nucleoside phosphorylase activity
A8704_RS11095	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
A8704_RS11110	COG1518	maintenance of DNA repeat elements
A8704_RS11115	COG3513	CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
A8704_RS11120	COG2267	carboxylic ester hydrolase activity
A8704_RS11130	COG1113	amino acid transport
A8704_RS11145	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
A8704_RS11155	COG0352	thiamine-phosphate diphosphorylase activity
A8704_RS11160	COG0351	phosphomethylpyrimidine kinase
A8704_RS11165	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
A8704_RS11175	COG1606	tRNA processing
A8704_RS11180	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
A8704_RS11185	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
A8704_RS11190	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
A8704_RS11195	COG1691	(AIR) carboxylase
A8704_RS11200	COG3875	lactate racemase activity
A8704_RS11205	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
A8704_RS11210	COG0310	cobalt ion transport
A8704_RS11215	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
A8704_RS11220	COG1122	ATPase activity
A8704_RS11245	COG4166	transmembrane transport
A8704_RS11255	COG3022	response to hydroperoxide
A8704_RS11260	COG2267	carboxylic ester hydrolase activity
A8704_RS11275	COG0604	alcohol dehydrogenase
A8704_RS11310	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
A8704_RS11330	COG2368	4-hydroxyphenylacetate
A8704_RS11335	COG2365	Tyrosine phosphatase family
A8704_RS11345	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
A8704_RS11350	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
A8704_RS11355	COG2508	Transcriptional regulator
A8704_RS11360	COG0778	Nitroreductase
A8704_RS11370	COG1028	Short-chain dehydrogenase reductase Sdr
A8704_RS11375	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
A8704_RS11390	COG0471	metal ion transport
A8704_RS11395	COG0431	NADPH-dependent FMN reductase
A8704_RS11395	COG3976	FMN-binding domain protein
A8704_RS11395	COG1053	succinate dehydrogenase
A8704_RS11415	COG1573	uracil-dna glycosylase
A8704_RS11420	COG3586	endonuclease activity
A8704_RS11425	COG1012	belongs to the aldehyde dehydrogenase family
A8704_RS11435	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
A8704_RS11440	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
A8704_RS11445	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
A8704_RS11450	COG4853	Protein conserved in bacteria
A8704_RS11460	COG5002	protein histidine kinase activity
A8704_RS11465	COG0745	RESPONSE REGULATOR receiver
A8704_RS11500	COG4695	Portal protein
A8704_RS11580	COG1278	Cold shock
A8704_RS11590	COG1554	hydrolase, family 65, central catalytic
A8704_RS11595	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
A8704_RS11605	COG3103	Sh3 type 3 domain protein
A8704_RS11605	COG0366	Alpha amylase catalytic
A8704_RS11610	COG0058	SHG alpha-glucan phosphorylase activity
A8704_RS11615	COG0297	glycogen (starch) synthase activity
A8704_RS11620	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
A8704_RS11625	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
A8704_RS11630	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
A8704_RS11635	COG4166	transmembrane transport
A8704_RS11640	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
A8704_RS11645	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
A8704_RS11650	COG2814	Major facilitator Superfamily
A8704_RS11655	COG0305	Participates in initiation and elongation during chromosome replication
A8704_RS11660	COG0359	binds to the 23S rRNA
A8704_RS11670	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
A8704_RS11675	COG0629	single-stranded DNA binding
A8704_RS11680	COG0360	Binds together with S18 to 16S ribosomal RNA
A8704_RS11690	COG0187	DNA topoisomerase II activity
A8704_RS11695	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
A8704_RS11700	COG2501	S4 domain
A8704_RS11705	COG0592	DNA-directed DNA polymerase activity
A8704_RS11710	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
A8704_RS11715	COG0594	ribonuclease P activity
A8704_RS11720	COG0706	membrane insertase activity
A8704_RS11725	COG4166	transmembrane transport
A8704_RS11735	COG1847	R3H domain protein
A8704_RS11740	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
A8704_RS11745	COG0445	tRNA wobble uridine modification
A8704_RS11785	COG1307	EDD domain protein, DegV family
A8704_RS11800	COG3479	Phenolic acid decarboxylase
A8704_RS11805	COG1695	Transcriptional regulator
A8704_RS11815	COG1012	belongs to the aldehyde dehydrogenase family
A8704_RS11815	COG1454	alcohol dehydrogenase
A8704_RS11820	COG1609	Transcriptional regulator
A8704_RS11830	COG1869	D-ribose catabolic process
A8704_RS11835	COG4975	Glucose uptake
A8704_RS11855	COG3730	PTS system glucitol sorbitol-specific
A8704_RS11860	COG3732	PTS system glucitol sorbitol-specific
A8704_RS11870	COG0028	Belongs to the TPP enzyme family
A8704_RS11875	COG1959	2 iron, 2 sulfur cluster binding
A8704_RS11880	COG0028	Belongs to the TPP enzyme family
A8704_RS11900	COG4512	PFAM Accessory gene regulator B
A8704_RS11920	COG1393	Belongs to the ArsC family
A8704_RS11930	COG2261	transglycosylase associated protein
A8704_RS11950	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
A8704_RS11955	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
A8704_RS11975	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
A8704_RS11995	COG1737	Transcriptional regulator
A8704_RS12000	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
A8704_RS12005	COG1349	DNA-binding transcription factor activity
A8704_RS12015	COG3414	Phosphotransferase system galactitol-specific IIB component
A8704_RS12020	COG3775	system Galactitol-specific IIC component
A8704_RS12035	COG3711	transcriptional antiterminator
A8704_RS12055	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
A8704_RS12070	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
A8704_RS12085	COG2211	Major facilitator Superfamily
A8704_RS12095	COG3328	transposase activity
A8704_RS12110	COG2190	(PTS) system
A8704_RS12110	COG1263	PTS System
A8704_RS12110	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
A8704_RS12115	COG2723	6-phospho-beta-galactosidase activity
A8704_RS12120	COG2723	6-phospho-beta-galactosidase activity
A8704_RS12125	COG3711	transcriptional antiterminator
A8704_RS12135	COG2723	6-phospho-beta-galactosidase activity
A8704_RS12145	COG2971	BadF BadG BcrA BcrD
A8704_RS12150	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
A8704_RS12155	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
A8704_RS12160	COG2188	Transcriptional regulator
A8704_RS12165	COG2267	carboxylic ester hydrolase activity
A8704_RS12175	COG2271	Major facilitator Superfamily
A8704_RS12190	COG1028	Short-chain dehydrogenase reductase Sdr
A8704_RS12205	COG2271	Major facilitator Superfamily
A8704_RS12210	COG0583	DNA-binding transcription factor activity
A8704_RS12215	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
A8704_RS12220	COG0710	3-dehydroquinate dehydratase activity
A8704_RS12240	COG0667	Aldo Keto reductase
A8704_RS12245	COG1609	Transcriptional regulator
A8704_RS12250	COG2017	converts alpha-aldose to the beta-anomer
A8704_RS12255	COG2190	(PTS) system
A8704_RS12255	COG2211	Major facilitator Superfamily
A8704_RS12275	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
A8704_RS12280	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
A8704_RS12285	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
A8704_RS12290	COG1609	Transcriptional regulator
A8704_RS12295	COG2944	sequence-specific DNA binding
A8704_RS12300	COG2184	nucleotidyltransferase activity
A8704_RS12320	COG0477	Major facilitator Superfamily
A8704_RS12330	COG1609	Transcriptional regulator
A8704_RS12335	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
A8704_RS12350	COG1874	Beta-galactosidase
A8704_RS12355	COG1114	Component of the transport system for branched-chain amino acids
A8704_RS12365	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
A8704_RS12415	COG0446	pyridine nucleotide-disulphide oxidoreductase
A8704_RS12425	COG3293	Transposase
A8704_RS12440	COG3590	peptidase
A8704_RS12445	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
A8704_RS12465	COG1937	Protein conserved in bacteria
A8704_RS12470	COG3118	belongs to the thioredoxin family
A8704_RS12475	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
A8704_RS12480	COG2217	Heavy metal translocating P-type atpase
A8704_RS12495	COG2226	methyltransferase
A8704_RS12540	COG0076	glutamate decarboxylase activity
A8704_RS12565	COG2826	transposase and inactivated derivatives, IS30 family
A8704_RS12570	COG2207	Transcriptional regulator
A8704_RS12605	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
A8704_RS12610	COG1968	undecaprenyl-diphosphatase activity
A8704_RS12630	COG0656	L-ascorbic acid biosynthetic process
A8704_RS12640	COG0737	Belongs to the 5'-nucleotidase family
A8704_RS12690	COG0477	Major facilitator Superfamily
A8704_RS12715	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
A8704_RS12730	COG0697	spore germination
A8704_RS12750	COG0071	Belongs to the small heat shock protein (HSP20) family
A8704_RS12765	COG1194	a g-specific adenine glycosylase
A8704_RS12775	COG3189	MarR family transcriptional regulator
A8704_RS12780	COG1393	Belongs to the ArsC family
A8704_RS12795	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
A8704_RS12805	COG1113	amino acid transport
A8704_RS12810	COG1757	Na H antiporter
A8704_RS12820	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
A8704_RS12825	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
A8704_RS12835	COG2315	Protein conserved in bacteria
A8704_RS12845	COG2217	Heavy metal translocating P-type atpase
A8704_RS12875	COG4989	oxidoreductase activity
A8704_RS12880	COG2151	metal-sulfur cluster biosynthetic enzyme
A8704_RS12885	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
A8704_RS12890	COG1882	Formate acetyltransferase
A8704_RS12895	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
A8704_RS12925	COG2814	Major facilitator Superfamily
A8704_RS12930	COG0803	Belongs to the bacterial solute-binding protein 9 family
A8704_RS12945	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
A8704_RS12950	COG0302	gtp cyclohydrolase
A8704_RS12960	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
A8704_RS12990	COG0640	Transcriptional regulator
A8704_RS12995	COG1272	protein, Hemolysin III
A8704_RS13010	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
A8704_RS13015	COG0628	permease
A8704_RS13020	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
A8704_RS13030	COG0531	amino acid
A8704_RS13040	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
A8704_RS13045	COG2365	Tyrosine phosphatase family
A8704_RS13050	COG4166	transmembrane transport
A8704_RS13055	COG0601	transmembrane transport
A8704_RS13065	COG0444	Belongs to the ABC transporter superfamily
A8704_RS13075	COG0516	GMP reductase activity
A8704_RS13080	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
A8704_RS13085	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
A8704_RS13100	COG1929	Belongs to the glycerate kinase type-1 family
A8704_RS13110	COG1562	ergosterol biosynthetic process
A8704_RS13115	COG1233	COG1233 Phytoene dehydrogenase and related
A8704_RS13120	COG2738	Putative neutral zinc metallopeptidase
A8704_RS13125	COG1307	EDD domain protein, DegV family
A8704_RS13160	COG0735	belongs to the Fur family
A8704_RS13190	COG2190	(PTS) system
A8704_RS13190	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
A8704_RS13190	COG1263	PTS System
A8704_RS13205	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
A8704_RS13205	COG3711	transcriptional antiterminator
A8704_RS13210	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
A8704_RS13210	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
A8704_RS13210	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
A8704_RS13215	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
A8704_RS13220	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
A8704_RS13220	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
A8704_RS13220	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
A8704_RS13225	COG0383	alpha-mannosidase activity
A8704_RS13235	COG0561	phosphatase activity
A8704_RS13250	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
A8704_RS13255	COG4619	ABC transporter
A8704_RS13260	COG0390	transport system, permease component
A8704_RS13270	COG1609	Transcriptional regulator
A8704_RS13275	COG0366	Alpha amylase catalytic
A8704_RS13280	COG2190	(PTS) system
A8704_RS13280	COG1263	PTS System
A8704_RS13280	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
A8704_RS13305	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
A8704_RS13310	COG1126	abc transporter atp-binding protein
A8704_RS13315	COG0765	amino acid transport
A8704_RS13320	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
A8704_RS13325	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
A8704_RS13330	COG0583	DNA-binding transcription factor activity
A8704_RS13345	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
A8704_RS13350	COG0357	Ribosomal RNA small subunit methyltransferase G
A8704_RS13360	COG1192	Involved in chromosome partitioning
A8704_RS13365	COG1475	DNA binding
A8704_RS13370	COG4481	Protein conserved in bacteria
A8704_RS13375	COG0012	GTP binding
A8704_RS13385	COG0516	GMP reductase activity
A8704_RS13385	COG0517	IMP dehydrogenase activity
A8704_RS13390	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
A8704_RS13410	COG1686	Belongs to the peptidase S11 family
A8704_RS13415	COG1247	-acetyltransferase
A8704_RS13455	COG0515	serine threonine protein kinase
A8704_RS13455	COG2815	serine threonine protein kinase
A8704_RS13465	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
A8704_RS13480	COG1846	Transcriptional regulator
A8704_RS13480	COG1940	carbohydrate kinase activity
A8704_RS13485	COG0628	permease
A8704_RS13490	COG0588	phosphoglycerate mutase activity
A8704_RS13545	COG0300	oxidoreductase activity
A8704_RS13550	COG1733	regulation of RNA biosynthetic process
A8704_RS13565	COG1012	belongs to the aldehyde dehydrogenase family
A8704_RS13575	COG1309	transcriptional regulator
A8704_RS13595	COG0367	asparagine synthase
A8704_RS13605	COG2814	Major facilitator Superfamily
A8704_RS13610	COG1733	regulation of RNA biosynthetic process
A8704_RS13615	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
A8704_RS13710	COG2217	Heavy metal translocating P-type atpase
A8704_RS13735	COG0531	amino acid
A8704_RS13750	COG1028	Short-chain dehydrogenase reductase Sdr
A8704_RS13755	COG1473	amidohydrolase
A8704_RS13765	COG1132	(ABC) transporter
A8704_RS13780	COG1028	Short-chain dehydrogenase reductase Sdr
A8704_RS13810	COG4221	oxidoreductase activity
A8704_RS13830	COG1073	alpha beta
A8704_RS13835	COG1028	Short-chain dehydrogenase reductase Sdr
A8704_RS13860	COG0667	Aldo Keto reductase
A8704_RS13875	COG0789	Transcriptional regulator
A8704_RS13890	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
A8704_RS13915	COG0803	Belongs to the bacterial solute-binding protein 9 family
A8704_RS13935	COG0741	lytic transglycosylase activity
A8704_RS13940	COG0789	Transcriptional regulator
A8704_RS13950	COG2723	6-phospho-beta-galactosidase activity
A8704_RS13955	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
A8704_RS13960	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
A8704_RS13995	COG0577	efflux transmembrane transporter activity
A8704_RS13995	COG1136	(ABC) transporter
A8704_RS14005	COG0640	Transcriptional regulator
A8704_RS14025	COG1914	H( )-stimulated, divalent metal cation uptake system
A8704_RS14035	COG2246	polysaccharide biosynthetic process
A8704_RS14040	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
A8704_RS14040	COG5549	protein import
A8704_RS14055	COG0559	Belongs to the binding-protein-dependent transport system permease family
A8704_RS14070	COG0410	ABC transporter
A8704_RS14105	COG4120	Belongs to the binding-protein-dependent transport system permease family
A8704_RS14110	COG1116	anion transmembrane transporter activity
A8704_RS14120	COG3293	Transposase
A8704_RS14125	COG2190	(PTS) system
A8704_RS14125	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
A8704_RS14125	COG1263	PTS System
A8704_RS14130	COG0778	Nitroreductase
A8704_RS14135	COG0561	phosphatase activity
A8704_RS14140	COG1609	Transcriptional regulator
A8704_RS14150	COG1132	(ABC) transporter
A8704_RS14160	COG3409	Peptidoglycan-binding domain 1 protein
A8704_RS14170	COG3293	Transposase
A8704_RS14175	COG2190	(PTS) system
A8704_RS14175	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
A8704_RS14175	COG1263	PTS System
A8704_RS14180	COG0778	Nitroreductase
A8704_RS14185	COG0561	phosphatase activity
A8704_RS14190	COG1609	Transcriptional regulator
A8704_RS14200	COG1132	(ABC) transporter
A8704_RS14210	COG3409	Peptidoglycan-binding domain 1 protein
A8704_RS14220	COG3293	Transposase
A8704_RS14225	COG1940	carbohydrate kinase activity
A8704_RS14250	COG0697	spore germination
A8704_RS14295	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
A8704_RS14305	COG0583	DNA-binding transcription factor activity
A8704_RS14320	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
A8704_RS14330	COG0242	peptide deformylase activity
A8704_RS14340	COG1328	CTP reductase activity
A8704_RS14350	COG2200	EAL domain
A8704_RS14390	COG2270	Major facilitator Superfamily
A8704_RS14405	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
A8704_RS14415	COG0561	phosphatase activity
A8704_RS14420	COG0488	(ABC) transporter
A8704_RS14450	COG0640	Transcriptional regulator
A8704_RS14460	COG1511	domain protein
A8704_RS14460	COG1511	domain protein
A8704_RS14480	COG2814	Major facilitator Superfamily
A8704_RS14485	COG1132	(ABC) transporter
A8704_RS14490	COG1132	(ABC) transporter
A8704_RS14495	COG0667	Aldo Keto reductase
A8704_RS14505	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
A8704_RS14515	COG3328	transposase activity
A8704_RS14525	COG1011	Hydrolase
A8704_RS14530	COG0110	maltose O-acetyltransferase activity
A8704_RS14535	COG0589	response to stress
A8704_RS14545	COG1028	Short-chain dehydrogenase reductase Sdr
A8704_RS14550	COG1063	alcohol dehydrogenase
A8704_RS14560	COG3328	transposase activity
A8704_RS14565	COG0583	DNA-binding transcription factor activity
A8704_RS14590	COG0456	acetyltransferase
A8704_RS14615	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
A8704_RS14635	COG0789	Transcriptional regulator
A8704_RS14650	COG4221	oxidoreductase activity
A8704_RS14660	COG4152	abc transporter atp-binding protein
A8704_RS14665	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
A8704_RS14680	COG0438	transferase activity, transferring glycosyl groups
A8704_RS14690	COG0583	DNA-binding transcription factor activity
A8704_RS14695	COG2855	membrane
A8704_RS14700	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
A8704_RS14710	COG2814	Major facilitator Superfamily
A8704_RS14720	COG2814	Major facilitator Superfamily
A8704_RS14765	COG1136	(ABC) transporter
A8704_RS14770	COG0577	efflux transmembrane transporter activity
A8704_RS14785	COG0789	Transcriptional regulator
A8704_RS14785	COG4978	Transcriptional regulator
A8704_RS14790	COG1811	Na channel or pump
A8704_RS14980	COG0561	phosphatase activity
A8704_RS15000	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
A8704_RS15110	COG0366	Alpha amylase catalytic
A8704_RS15410	COG3048	D-serine ammonia-lyase activity
A8704_RS15415	COG3048	D-serine ammonia-lyase activity
A8704_RS15640	COG0151	Belongs to the GarS family
A8704_RS15685	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
A8704_RS15875	COG2723	6-phospho-beta-galactosidase activity