locus-tag	class	description
C7M31_RS00090	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
C7M31_RS00145	COG0393	Putative heavy-metal-binding
C7M31_RS00160	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
C7M31_RS00165	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
C7M31_RS00165	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
C7M31_RS00170	COG5416	Lipopolysaccharide assembly protein A domain
C7M31_RS00175	COG0300	oxidoreductase activity
C7M31_RS00180	COG1234	tRNA 3'-trailer cleavage
C7M31_RS00190	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
C7M31_RS00195	COG1349	DNA-binding transcription factor activity
C7M31_RS00200	COG1105	Belongs to the carbohydrate kinase PfkB family
C7M31_RS00205	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
C7M31_RS00205	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C7M31_RS00205	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C7M31_RS00210	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
C7M31_RS00235	COG0297	glycogen (starch) synthase activity
C7M31_RS00240	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
C7M31_RS00245	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
C7M31_RS00255	COG0489	protein tyrosine kinase activity
C7M31_RS00265	COG0322	excinuclease ABC activity
C7M31_RS00270	COG1126	abc transporter atp-binding protein
C7M31_RS00275	COG0765	amino acid transport
C7M31_RS00295	COG0218	Necessary for normal cell division and for the maintenance of normal septation
C7M31_RS00300	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
C7M31_RS00305	COG0544	peptidyl-prolyl cis-trans isomerase activity
C7M31_RS00310	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
C7M31_RS00335	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
C7M31_RS00340	COG0268	Binds directly to 16S ribosomal RNA
C7M31_RS00345	COG1466	dna polymerase III delta subunit
C7M31_RS00350	COG2333	competence protein COMEC
C7M31_RS00350	COG0658	competence protein
C7M31_RS00355	COG2131	deaminase
C7M31_RS00360	COG1596	polysaccharide export
C7M31_RS00360	COG1555	photosystem II stabilization
C7M31_RS00365	COG3480	Lon protease (S16) C-terminal proteolytic domain
C7M31_RS00370	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
C7M31_RS00375	COG0742	ribosomal rna small subunit methyltransferase
C7M31_RS00380	COG4471	UPF0298 protein
C7M31_RS00385	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
C7M31_RS00390	COG0772	Belongs to the SEDS family
C7M31_RS00420	COG0483	inositol monophosphate 1-phosphatase activity
C7M31_RS00425	COG4476	Belongs to the UPF0223 family
C7M31_RS00430	COG0039	L-malate dehydrogenase activity
C7M31_RS00455	COG0242	peptide deformylase activity
C7M31_RS00470	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
C7M31_RS00475	COG1597	lipid kinase activity
C7M31_RS00485	COG3584	3D domain protein
C7M31_RS00485	COG1388	LysM domain
C7M31_RS00490	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
C7M31_RS00495	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
C7M31_RS00525	COG0569	domain protein
C7M31_RS00530	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
C7M31_RS00535	COG0482	sulfurtransferase activity
C7M31_RS00545	COG1104	cysteine desulfurase activity
C7M31_RS00550	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
C7M31_RS00560	COG0494	nUDIX hydrolase
C7M31_RS00565	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
C7M31_RS00570	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
C7M31_RS00575	COG3599	regulation of cell shape
C7M31_RS00585	COG0762	integral membrane protein
C7M31_RS00590	COG1799	cell septum assembly
C7M31_RS00605	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
C7M31_RS00610	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
C7M31_RS00615	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
C7M31_RS00620	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
C7M31_RS00635	COG0275	rRNA processing
C7M31_RS00640	COG2001	Belongs to the MraZ family
C7M31_RS00660	COG1674	ftsk spoiiie
C7M31_RS00665	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
C7M31_RS00675	COG1114	Component of the transport system for branched-chain amino acids
C7M31_RS00685	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
C7M31_RS00690	COG0628	permease
C7M31_RS00700	COG2706	6-phosphogluconolactonase activity
C7M31_RS00705	COG3142	Participates in the control of copper homeostasis
C7M31_RS00710	COG0564	pseudouridine synthase activity
C7M31_RS00715	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
C7M31_RS00720	COG2357	RelA SpoT domain protein
C7M31_RS00730	COG1164	Oligoendopeptidase f
C7M31_RS00740	COG4862	establishment of competence for transformation
C7M31_RS00745	COG1393	Belongs to the ArsC family
C7M31_RS00750	COG1234	tRNA 3'-trailer cleavage
C7M31_RS00890	COG1098	S1 RNA binding domain
C7M31_RS00900	COG0586	Pfam SNARE associated Golgi protein
C7M31_RS00910	COG0647	UMP catabolic process
C7M31_RS00915	COG4470	Protein conserved in bacteria
C7M31_RS00920	COG0737	Belongs to the 5'-nucleotidase family
C7M31_RS00930	COG1113	amino acid transport
C7M31_RS00935	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
C7M31_RS00940	COG0827	DNA restriction-modification system
C7M31_RS00970	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
C7M31_RS00980	COG0217	transcriptional regulatory protein
C7M31_RS00995	COG1609	Transcriptional regulator
C7M31_RS01000	COG0006	proline dipeptidase activity
C7M31_RS01005	COG0789	Transcriptional regulator
C7M31_RS01020	COG0668	transmembrane transport
C7M31_RS01025	COG1473	amidohydrolase
C7M31_RS01030	COG2171	N-acyltransferase activity
C7M31_RS01035	COG0517	IMP dehydrogenase activity
C7M31_RS01045	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
C7M31_RS01050	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
C7M31_RS01055	COG1719	4-vinyl reductase, 4VR
C7M31_RS01060	COG3118	belongs to the thioredoxin family
C7M31_RS01065	COG1193	negative regulation of DNA recombination
C7M31_RS01075	COG3906	Belongs to the UPF0473 family
C7M31_RS01080	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
C7M31_RS01085	COG4472	Bacterial protein of unknown function (DUF965)
C7M31_RS01090	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
C7M31_RS01095	COG0513	Belongs to the DEAD box helicase family
C7M31_RS01100	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
C7M31_RS01105	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
C7M31_RS01110	COG1862	Preprotein translocase
C7M31_RS01115	COG0343	queuine tRNA-ribosyltransferase activity
C7M31_RS01120	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
C7M31_RS01125	COG2255	four-way junction helicase activity
C7M31_RS01130	COG0632	four-way junction helicase activity
C7M31_RS01155	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
C7M31_RS01160	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
C7M31_RS01165	COG1692	metallophosphoesterase
C7M31_RS01170	COG1418	mRNA catabolic process
C7M31_RS01175	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
C7M31_RS01180	COG1058	Belongs to the CinA family
C7M31_RS01180	COG1546	Belongs to the CinA family
C7M31_RS01185	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
C7M31_RS01190	COG1426	Protein conserved in bacteria
C7M31_RS01195	COG0612	Peptidase, M16
C7M31_RS01200	COG0612	Peptidase, M16
C7M31_RS01205	COG0527	aspartate kinase activity
C7M31_RS01215	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C7M31_RS01220	COG1126	abc transporter atp-binding protein
C7M31_RS01225	COG0765	amino acid transport
C7M31_RS01230	COG2894	cell division
C7M31_RS01235	COG0850	regulation of cytokinetic process
C7M31_RS01245	COG1792	Involved in formation and maintenance of cell shape
C7M31_RS01250	COG1077	Cell shape determining protein MreB Mrl
C7M31_RS01255	COG2003	Belongs to the UPF0758 family
C7M31_RS01260	COG0285	dihydrofolate synthase activity
C7M31_RS01265	COG0525	valine-tRNA ligase activity
C7M31_RS01275	COG1181	Belongs to the D-alanine--D-alanine ligase family
C7M31_RS01275	COG2918	glutathione biosynthetic process
C7M31_RS01280	COG0301	tRNA thio-modification
C7M31_RS01285	COG1104	cysteine desulfurase activity
C7M31_RS01290	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
C7M31_RS01295	COG1956	GAF domain-containing protein
C7M31_RS01300	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
C7M31_RS01305	COG4493	Belongs to the UPF0637 family
C7M31_RS01320	COG0640	Transcriptional regulator
C7M31_RS01335	COG3716	PTS system mannose fructose sorbose family IID component
C7M31_RS01340	COG3715	PTS system
C7M31_RS01345	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C7M31_RS01350	COG1609	Transcriptional regulator
C7M31_RS01355	COG0189	ligase activity
C7M31_RS01355	COG2918	glutathione biosynthetic process
C7M31_RS01360	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
C7M31_RS01375	COG0589	response to stress
C7M31_RS01395	COG1181	Belongs to the D-alanine--D-alanine ligase family
C7M31_RS01415	COG1464	Belongs to the NlpA lipoprotein family
C7M31_RS01420	COG2011	ABC-type metal ion transport system permease component
C7M31_RS01425	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
C7M31_RS01430	COG0509	glycine decarboxylation via glycine cleavage system
C7M31_RS01435	COG0772	Belongs to the SEDS family
C7M31_RS01445	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
C7M31_RS01450	COG1077	Cell shape determining protein MreB Mrl
C7M31_RS01460	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
C7M31_RS01465	COG0355	proton-transporting ATP synthase activity, rotational mechanism
C7M31_RS01470	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
C7M31_RS01475	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
C7M31_RS01480	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
C7M31_RS01485	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
C7M31_RS01490	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
C7M31_RS01495	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
C7M31_RS01500	COG0356	it plays a direct role in the translocation of protons across the membrane
C7M31_RS01505	COG2233	PERMEase
C7M31_RS01515	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
C7M31_RS01520	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
C7M31_RS01525	COG0009	L-threonylcarbamoyladenylate synthase
C7M31_RS01530	COG2890	protein-(glutamine-N5) methyltransferase activity
C7M31_RS01535	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
C7M31_RS01540	COG1435	thymidine kinase activity
C7M31_RS01545	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
C7M31_RS01550	COG3442	glutamine amidotransferase
C7M31_RS01555	COG1482	cell wall glycoprotein biosynthetic process
C7M31_RS01560	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
C7M31_RS01570	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
C7M31_RS01585	COG1132	(ABC) transporter
C7M31_RS01600	COG0726	polysaccharide deacetylase
C7M31_RS01640	COG4932	domain protein
C7M31_RS01640	COG4886	Leucine-rich repeat (LRR) protein
C7M31_RS01685	COG1132	(ABC) transporter
C7M31_RS01695	COG1136	(ABC) transporter
C7M31_RS01695	COG0577	efflux transmembrane transporter activity
C7M31_RS01705	COG0166	Belongs to the GPI family
C7M31_RS01710	COG4975	Glucose uptake
C7M31_RS01715	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
C7M31_RS01720	COG3850	Histidine kinase
C7M31_RS01720	COG5002	protein histidine kinase activity
C7M31_RS01725	COG0745	RESPONSE REGULATOR receiver
C7M31_RS01730	COG2848	UPF0210 protein
C7M31_RS01735	COG3830	Belongs to the UPF0237 family
C7M31_RS01760	COG0477	Major facilitator Superfamily
C7M31_RS01780	COG0791	NLP P60 protein
C7M31_RS01785	COG1522	sequence-specific DNA binding
C7M31_RS01800	COG3706	GGDEF domain
C7M31_RS01805	COG0488	(ABC) transporter
C7M31_RS01825	COG1263	PTS System
C7M31_RS01825	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C7M31_RS01825	COG2190	(PTS) system
C7M31_RS01830	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
C7M31_RS01835	COG1307	EDD domain protein, DegV family
C7M31_RS01850	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
C7M31_RS01860	COG4120	Belongs to the binding-protein-dependent transport system permease family
C7M31_RS01870	COG0446	pyridine nucleotide-disulphide oxidoreductase
C7M31_RS01875	COG2084	Dehydrogenase
C7M31_RS01880	COG0861	Integral membrane protein TerC family
C7M31_RS01885	COG0110	maltose O-acetyltransferase activity
C7M31_RS01890	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
C7M31_RS01895	COG0140	phosphoribosyl-ATP diphosphatase activity
C7M31_RS01900	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
C7M31_RS01905	COG0107	imidazoleglycerol-phosphate synthase activity
C7M31_RS01910	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
C7M31_RS01915	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
C7M31_RS01920	COG0131	Imidazoleglycerol-phosphate dehydratase
C7M31_RS01925	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
C7M31_RS01930	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
C7M31_RS01935	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
C7M31_RS01940	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
C7M31_RS01960	COG0789	Transcriptional regulator
C7M31_RS01965	COG0300	oxidoreductase activity
C7M31_RS01975	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
C7M31_RS01990	COG3548	integral membrane protein
C7M31_RS02010	COG1368	sulfuric ester hydrolase activity
C7M31_RS02015	COG0584	glycerophosphoryl diester phosphodiesterase
C7M31_RS02020	COG0492	ferredoxin-NADP+ reductase activity
C7M31_RS02035	COG2326	polyphosphate kinase activity
C7M31_RS02040	COG0778	Nitroreductase
C7M31_RS02050	COG0328	RNA-DNA hybrid ribonuclease activity
C7M31_RS02060	COG1609	Transcriptional regulator
C7M31_RS02070	COG0673	inositol 2-dehydrogenase activity
C7M31_RS02075	COG0673	inositol 2-dehydrogenase activity
C7M31_RS02080	COG0025	NhaP-type Na H and K H
C7M31_RS02085	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
C7M31_RS02090	COG1335	isochorismatase
C7M31_RS02100	COG1131	(ABC) transporter
C7M31_RS02105	COG1725	Transcriptional regulator
C7M31_RS02145	COG0028	Belongs to the TPP enzyme family
C7M31_RS02155	COG1073	alpha beta
C7M31_RS02160	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
C7M31_RS02165	COG0626	cystathionine gamma-synthase activity
C7M31_RS02195	COG0095	Lipoate-protein ligase
C7M31_RS02200	COG1705	Flagellar rod assembly protein muramidase FlgJ
C7M31_RS02210	COG3716	PTS system mannose fructose sorbose family IID component
C7M31_RS02215	COG3715	PTS system
C7M31_RS02220	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C7M31_RS02225	COG2188	Transcriptional regulator
C7M31_RS02230	COG0589	response to stress
C7M31_RS02235	COG0564	pseudouridine synthase activity
C7M31_RS02250	COG4640	response to antibiotic
C7M31_RS02255	COG1396	sequence-specific DNA binding
C7M31_RS02270	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
C7M31_RS02280	COG2188	Transcriptional regulator
C7M31_RS02285	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
C7M31_RS02295	COG1418	mRNA catabolic process
C7M31_RS02325	COG1253	flavin adenine dinucleotide binding
C7M31_RS02330	COG1780	Probably involved in ribonucleotide reductase function
C7M31_RS02335	COG0025	NhaP-type Na H and K H
C7M31_RS02340	COG2814	Major facilitator Superfamily
C7M31_RS02345	COG0789	Transcriptional regulator
C7M31_RS02350	COG0604	alcohol dehydrogenase
C7M31_RS02360	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
C7M31_RS02365	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C7M31_RS02370	COG0436	Aminotransferase
C7M31_RS02375	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
C7M31_RS02390	COG0583	DNA-binding transcription factor activity
C7M31_RS02395	COG0702	epimerase
C7M31_RS02405	COG1074	ATP-dependent DNA helicase activity
C7M31_RS02410	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
C7M31_RS02420	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
C7M31_RS02425	COG0284	orotidine-5'-phosphate decarboxylase activity
C7M31_RS02430	COG0167	dihydroorotate dehydrogenase activity
C7M31_RS02435	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
C7M31_RS02440	COG0505	Belongs to the CarA family
C7M31_RS02445	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
C7M31_RS02450	COG0540	Belongs to the ATCase OTCase family
C7M31_RS02455	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
C7M31_RS02460	COG2508	Transcriptional regulator
C7M31_RS02465	COG2233	PERMEase
C7M31_RS02470	COG2252	PERMEase
C7M31_RS02490	COG1215	transferase activity, transferring glycosyl groups
C7M31_RS02500	COG0151	Belongs to the GarS family
C7M31_RS02505	COG0138	bifunctional purine biosynthesis protein purh
C7M31_RS02510	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
C7M31_RS02515	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
C7M31_RS02525	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
C7M31_RS02530	COG0047	phosphoribosylformylglycinamidine synthase activity
C7M31_RS02535	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
C7M31_RS02540	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
C7M31_RS02545	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
C7M31_RS02555	COG0431	NADPH-dependent FMN reductase
C7M31_RS02555	COG1053	succinate dehydrogenase
C7M31_RS02555	COG3976	FMN-binding domain protein
C7M31_RS02560	COG3976	FMN-binding domain protein
C7M31_RS02560	COG1053	succinate dehydrogenase
C7M31_RS02560	COG0431	NADPH-dependent FMN reductase
C7M31_RS02565	COG0095	Lipoate-protein ligase
C7M31_RS02570	COG2365	Tyrosine phosphatase family
C7M31_RS02590	COG1136	(ABC) transporter
C7M31_RS02605	COG1725	Transcriptional regulator
C7M31_RS02610	COG1131	(ABC) transporter
C7M31_RS02620	COG0589	response to stress
C7M31_RS02630	COG2246	polysaccharide biosynthetic process
C7M31_RS02635	COG1943	Transposase
C7M31_RS02655	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
C7M31_RS02685	COG0561	phosphatase activity
C7M31_RS02695	COG0110	maltose O-acetyltransferase activity
C7M31_RS02700	COG1051	belongs to the nudix hydrolase family
C7M31_RS02735	COG1827	regulation of RNA biosynthetic process
C7M31_RS02740	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
C7M31_RS02745	COG1309	transcriptional regulator
C7M31_RS02755	COG1131	(ABC) transporter
C7M31_RS02760	COG3048	D-serine ammonia-lyase activity
C7M31_RS02765	COG2723	6-phospho-beta-galactosidase activity
C7M31_RS02770	COG2723	6-phospho-beta-galactosidase activity
C7M31_RS02775	COG1447	Phosphotransferase system cellobiose-specific component IIA
C7M31_RS02780	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C7M31_RS02785	COG2188	Transcriptional regulator
C7M31_RS02790	COG1216	Glycosyl transferase, family 2
C7M31_RS02805	COG0561	phosphatase activity
C7M31_RS02810	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
C7M31_RS02835	COG0716	FMN binding
C7M31_RS02855	COG0710	3-dehydroquinate dehydratase activity
C7M31_RS02860	COG0531	amino acid
C7M31_RS02905	COG4720	Psort location CytoplasmicMembrane, score
C7M31_RS02910	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
C7M31_RS02925	COG4990	cell redox homeostasis
C7M31_RS02940	COG1811	Na channel or pump
C7M31_RS02945	COG0789	Transcriptional regulator
C7M31_RS02945	COG4978	Transcriptional regulator
C7M31_RS02960	COG0577	efflux transmembrane transporter activity
C7M31_RS02965	COG1136	(ABC) transporter
C7M31_RS03010	COG2814	Major facilitator Superfamily
C7M31_RS03020	COG2814	Major facilitator Superfamily
C7M31_RS03030	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
C7M31_RS03035	COG2855	membrane
C7M31_RS03040	COG0583	DNA-binding transcription factor activity
C7M31_RS03050	COG0438	transferase activity, transferring glycosyl groups
C7M31_RS03065	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
C7M31_RS03070	COG4152	abc transporter atp-binding protein
C7M31_RS03080	COG4221	oxidoreductase activity
C7M31_RS03095	COG0789	Transcriptional regulator
C7M31_RS03120	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
C7M31_RS03145	COG0456	acetyltransferase
C7M31_RS03170	COG0583	DNA-binding transcription factor activity
C7M31_RS03180	COG1063	alcohol dehydrogenase
C7M31_RS03185	COG1028	Short-chain dehydrogenase reductase Sdr
C7M31_RS03195	COG0589	response to stress
C7M31_RS03200	COG0110	maltose O-acetyltransferase activity
C7M31_RS03205	COG1011	Hydrolase
C7M31_RS03220	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
C7M31_RS03230	COG0667	Aldo Keto reductase
C7M31_RS03235	COG1132	(ABC) transporter
C7M31_RS03240	COG1132	(ABC) transporter
C7M31_RS03245	COG2814	Major facilitator Superfamily
C7M31_RS03260	COG1511	domain protein
C7M31_RS03260	COG1511	domain protein
C7M31_RS03270	COG0640	Transcriptional regulator
C7M31_RS03295	COG1943	Transposase
C7M31_RS03305	COG0488	(ABC) transporter
C7M31_RS03310	COG0561	phosphatase activity
C7M31_RS03320	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
C7M31_RS03335	COG2270	Major facilitator Superfamily
C7M31_RS03375	COG2200	EAL domain
C7M31_RS03385	COG1328	CTP reductase activity
C7M31_RS03395	COG0242	peptide deformylase activity
C7M31_RS03405	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
C7M31_RS03420	COG0583	DNA-binding transcription factor activity
C7M31_RS03430	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
C7M31_RS03480	COG0697	spore germination
C7M31_RS03505	COG1940	carbohydrate kinase activity
C7M31_RS03510	COG1132	(ABC) transporter
C7M31_RS03520	COG0778	Nitroreductase
C7M31_RS03525	COG2190	(PTS) system
C7M31_RS03525	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C7M31_RS03525	COG1263	PTS System
C7M31_RS03535	COG4120	Belongs to the binding-protein-dependent transport system permease family
C7M31_RS03570	COG0410	ABC transporter
C7M31_RS03585	COG0559	Belongs to the binding-protein-dependent transport system permease family
C7M31_RS03600	COG5549	protein import
C7M31_RS03600	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
C7M31_RS03605	COG2246	polysaccharide biosynthetic process
C7M31_RS03615	COG1914	H( )-stimulated, divalent metal cation uptake system
C7M31_RS03635	COG0640	Transcriptional regulator
C7M31_RS03645	COG0577	efflux transmembrane transporter activity
C7M31_RS03645	COG1136	(ABC) transporter
C7M31_RS03680	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C7M31_RS03685	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C7M31_RS03690	COG2723	6-phospho-beta-galactosidase activity
C7M31_RS03700	COG0789	Transcriptional regulator
C7M31_RS03705	COG0741	lytic transglycosylase activity
C7M31_RS03725	COG0803	Belongs to the bacterial solute-binding protein 9 family
C7M31_RS03750	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
C7M31_RS03765	COG4221	oxidoreductase activity
C7M31_RS03795	COG1028	Short-chain dehydrogenase reductase Sdr
C7M31_RS03810	COG1132	(ABC) transporter
C7M31_RS03815	COG1132	(ABC) transporter
C7M31_RS03825	COG1473	amidohydrolase
C7M31_RS03830	COG1028	Short-chain dehydrogenase reductase Sdr
C7M31_RS03845	COG0531	amino acid
C7M31_RS03870	COG2217	Heavy metal translocating P-type atpase
C7M31_RS03925	COG1063	alcohol dehydrogenase
C7M31_RS03965	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
C7M31_RS03970	COG1733	regulation of RNA biosynthetic process
C7M31_RS03975	COG2814	Major facilitator Superfamily
C7M31_RS03985	COG0367	asparagine synthase
C7M31_RS03990	COG3279	Response regulator of the LytR AlgR family
C7M31_RS04005	COG1309	transcriptional regulator
C7M31_RS04015	COG1012	belongs to the aldehyde dehydrogenase family
C7M31_RS04030	COG1733	regulation of RNA biosynthetic process
C7M31_RS04035	COG0300	oxidoreductase activity
C7M31_RS04055	COG0667	Aldo Keto reductase
C7M31_RS04060	COG0477	Major facilitator Superfamily
C7M31_RS04070	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
C7M31_RS04075	COG1120	ATPase activity
C7M31_RS04080	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C7M31_RS04085	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C7M31_RS04090	COG1309	transcriptional regulator
C7M31_RS04100	COG4221	oxidoreductase activity
C7M31_RS04105	COG0110	maltose O-acetyltransferase activity
C7M31_RS04110	COG1028	Short-chain dehydrogenase reductase Sdr
C7M31_RS04145	COG0481	GTPase activity
C7M31_RS04155	COG2816	NAD+ diphosphatase activity
C7M31_RS04165	COG1053	succinate dehydrogenase
C7M31_RS04175	COG0783	Belongs to the Dps family
C7M31_RS04185	COG2723	6-phospho-beta-galactosidase activity
C7M31_RS04190	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C7M31_RS04200	COG1943	Transposase
C7M31_RS04210	COG0789	Transcriptional regulator
C7M31_RS04260	COG1136	(ABC) transporter
C7M31_RS04260	COG0577	efflux transmembrane transporter activity
C7M31_RS04270	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
C7M31_RS04290	COG1376	ErfK ybiS ycfS ynhG family protein
C7M31_RS04295	COG0656	L-ascorbic acid biosynthetic process
C7M31_RS04310	COG0477	Major facilitator Superfamily
C7M31_RS04340	COG0588	phosphoglycerate mutase activity
C7M31_RS04345	COG0628	permease
C7M31_RS04350	COG1846	Transcriptional regulator
C7M31_RS04350	COG1940	carbohydrate kinase activity
C7M31_RS04360	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
C7M31_RS04370	COG0515	serine threonine protein kinase
C7M31_RS04370	COG2815	serine threonine protein kinase
C7M31_RS04410	COG1247	-acetyltransferase
C7M31_RS04415	COG1686	Belongs to the peptidase S11 family
C7M31_RS04435	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
C7M31_RS04450	COG0012	GTP binding
C7M31_RS04455	COG4481	Protein conserved in bacteria
C7M31_RS04460	COG1475	DNA binding
C7M31_RS04465	COG1192	Involved in chromosome partitioning
C7M31_RS04475	COG0357	Ribosomal RNA small subunit methyltransferase G
C7M31_RS04480	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
C7M31_RS04490	COG0583	DNA-binding transcription factor activity
C7M31_RS04495	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C7M31_RS04500	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C7M31_RS04505	COG0765	amino acid transport
C7M31_RS04510	COG1126	abc transporter atp-binding protein
C7M31_RS04515	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C7M31_RS04540	COG2190	(PTS) system
C7M31_RS04540	COG1263	PTS System
C7M31_RS04540	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C7M31_RS04550	COG1609	Transcriptional regulator
C7M31_RS04560	COG0390	transport system, permease component
C7M31_RS04565	COG4619	ABC transporter
C7M31_RS04570	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
C7M31_RS04585	COG0561	phosphatase activity
C7M31_RS04600	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C7M31_RS04600	COG1263	PTS System
C7M31_RS04600	COG2190	(PTS) system
C7M31_RS04630	COG0735	belongs to the Fur family
C7M31_RS04665	COG1307	EDD domain protein, DegV family
C7M31_RS04675	COG2738	Putative neutral zinc metallopeptidase
C7M31_RS04680	COG1233	COG1233 Phytoene dehydrogenase and related
C7M31_RS04685	COG1562	ergosterol biosynthetic process
C7M31_RS04695	COG1929	Belongs to the glycerate kinase type-1 family
C7M31_RS04710	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
C7M31_RS04715	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
C7M31_RS04720	COG0516	GMP reductase activity
C7M31_RS04725	COG2365	Tyrosine phosphatase family
C7M31_RS04730	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
C7M31_RS04740	COG0531	amino acid
C7M31_RS04745	COG3158	transport of potassium into the cell
C7M31_RS04750	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
C7M31_RS04755	COG0628	permease
C7M31_RS04760	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
C7M31_RS04775	COG1272	protein, Hemolysin III
C7M31_RS04780	COG0640	Transcriptional regulator
C7M31_RS04820	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
C7M31_RS04830	COG0302	gtp cyclohydrolase
C7M31_RS04835	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
C7M31_RS04850	COG0803	Belongs to the bacterial solute-binding protein 9 family
C7M31_RS04855	COG2814	Major facilitator Superfamily
C7M31_RS04885	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
C7M31_RS04890	COG1882	Formate acetyltransferase
C7M31_RS04895	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
C7M31_RS04900	COG2151	metal-sulfur cluster biosynthetic enzyme
C7M31_RS04905	COG4989	oxidoreductase activity
C7M31_RS04935	COG2217	Heavy metal translocating P-type atpase
C7M31_RS04945	COG2315	Protein conserved in bacteria
C7M31_RS04955	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
C7M31_RS04960	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
C7M31_RS04975	COG1113	amino acid transport
C7M31_RS04985	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
C7M31_RS05000	COG1393	Belongs to the ArsC family
C7M31_RS05005	COG3189	MarR family transcriptional regulator
C7M31_RS05015	COG1194	a g-specific adenine glycosylase
C7M31_RS05030	COG0071	Belongs to the small heat shock protein (HSP20) family
C7M31_RS05050	COG0697	spore germination
C7M31_RS05065	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
C7M31_RS05090	COG0477	Major facilitator Superfamily
C7M31_RS05145	COG0737	Belongs to the 5'-nucleotidase family
C7M31_RS05155	COG0656	L-ascorbic acid biosynthetic process
C7M31_RS05175	COG1968	undecaprenyl-diphosphatase activity
C7M31_RS05180	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
C7M31_RS05215	COG2207	Transcriptional regulator
C7M31_RS05240	COG0076	glutamate decarboxylase activity
C7M31_RS05290	COG2226	methyltransferase
C7M31_RS05305	COG2217	Heavy metal translocating P-type atpase
C7M31_RS05310	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
C7M31_RS05315	COG3118	belongs to the thioredoxin family
C7M31_RS05320	COG1937	Protein conserved in bacteria
C7M31_RS05340	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
C7M31_RS05345	COG3590	peptidase
C7M31_RS05360	COG0446	pyridine nucleotide-disulphide oxidoreductase
C7M31_RS05410	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
C7M31_RS05420	COG1114	Component of the transport system for branched-chain amino acids
C7M31_RS05430	COG1874	Beta-galactosidase
C7M31_RS05435	COG1609	Transcriptional regulator
C7M31_RS05445	COG0477	Major facilitator Superfamily
C7M31_RS05465	COG2184	nucleotidyltransferase activity
C7M31_RS05470	COG2944	sequence-specific DNA binding
C7M31_RS05475	COG1609	Transcriptional regulator
C7M31_RS05480	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
C7M31_RS05485	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
C7M31_RS05490	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
C7M31_RS05510	COG2211	Major facilitator Superfamily
C7M31_RS05510	COG2190	(PTS) system
C7M31_RS05515	COG2017	converts alpha-aldose to the beta-anomer
C7M31_RS05520	COG1609	Transcriptional regulator
C7M31_RS05525	COG0667	Aldo Keto reductase
C7M31_RS05545	COG0710	3-dehydroquinate dehydratase activity
C7M31_RS05550	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
C7M31_RS05555	COG0583	DNA-binding transcription factor activity
C7M31_RS05560	COG2271	Major facilitator Superfamily
C7M31_RS05575	COG1028	Short-chain dehydrogenase reductase Sdr
C7M31_RS05590	COG2271	Major facilitator Superfamily
C7M31_RS05610	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C7M31_RS05615	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
C7M31_RS05620	COG2971	BadF BadG BcrA BcrD
C7M31_RS05630	COG2723	6-phospho-beta-galactosidase activity
C7M31_RS05640	COG3711	transcriptional antiterminator
C7M31_RS05645	COG2723	6-phospho-beta-galactosidase activity
C7M31_RS05650	COG2723	6-phospho-beta-galactosidase activity
C7M31_RS05655	COG2190	(PTS) system
C7M31_RS05655	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C7M31_RS05655	COG1263	PTS System
C7M31_RS05675	COG2211	Major facilitator Superfamily
C7M31_RS05690	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
C7M31_RS05705	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
C7M31_RS05710	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
C7M31_RS05715	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C7M31_RS05715	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C7M31_RS05715	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
C7M31_RS05720	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C7M31_RS05735	COG3711	transcriptional antiterminator
C7M31_RS05745	COG3775	system Galactitol-specific IIC component
C7M31_RS05750	COG3414	Phosphotransferase system galactitol-specific IIB component
C7M31_RS05760	COG1349	DNA-binding transcription factor activity
C7M31_RS05765	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
C7M31_RS05775	COG0110	maltose O-acetyltransferase activity
C7M31_RS05780	COG2160	L-arabinose isomerase activity
C7M31_RS05800	COG1609	Transcriptional regulator
C7M31_RS05805	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
C7M31_RS05830	COG2261	transglycosylase associated protein
C7M31_RS05840	COG1393	Belongs to the ArsC family
C7M31_RS05860	COG4512	PFAM Accessory gene regulator B
C7M31_RS05875	COG1304	FMN binding
C7M31_RS05880	COG0028	Belongs to the TPP enzyme family
C7M31_RS05885	COG1959	2 iron, 2 sulfur cluster binding
C7M31_RS05890	COG0028	Belongs to the TPP enzyme family
C7M31_RS05905	COG0235	Class ii aldolase
C7M31_RS05910	COG4806	L-rhamnose isomerase
C7M31_RS05915	COG3254	rhamnose metabolic process
C7M31_RS05920	COG1070	Carbohydrate kinase
C7M31_RS05925	COG2814	Major facilitator Superfamily
C7M31_RS05930	COG2207	Transcriptional regulator
C7M31_RS05935	COG1349	DNA-binding transcription factor activity
C7M31_RS05950	COG3775	system Galactitol-specific IIC component
C7M31_RS05965	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C7M31_RS05965	COG1263	PTS System
C7M31_RS05965	COG2190	(PTS) system
C7M31_RS05985	COG1737	Transcriptional regulator
C7M31_RS05990	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C7M31_RS05990	COG1263	PTS System
C7M31_RS06010	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C7M31_RS06010	COG1263	PTS System
C7M31_RS06020	COG1609	Transcriptional regulator
C7M31_RS06035	COG2723	6-phospho-beta-galactosidase activity
C7M31_RS06040	COG1940	carbohydrate kinase activity
C7M31_RS06045	COG0383	alpha-mannosidase activity
C7M31_RS06055	COG2188	Transcriptional regulator
C7M31_RS06065	COG3842	ATPase activity
C7M31_RS06075	COG2207	Transcriptional regulator
C7M31_RS06075	COG4753	response regulator
C7M31_RS06080	COG2972	Histidine kinase
C7M31_RS06090	COG0366	Alpha amylase catalytic
C7M31_RS06100	COG0395	ABC-type sugar transport system, permease component
C7M31_RS06115	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
C7M31_RS06115	COG2207	Transcriptional regulator
C7M31_RS06120	COG1132	(ABC) transporter
C7M31_RS06125	COG1132	(ABC) transporter
C7M31_RS06130	COG2188	Transcriptional regulator
C7M31_RS06145	COG3732	PTS system glucitol sorbitol-specific
C7M31_RS06150	COG3730	PTS system glucitol sorbitol-specific
C7M31_RS06170	COG4975	Glucose uptake
C7M31_RS06175	COG1869	D-ribose catabolic process
C7M31_RS06185	COG1609	Transcriptional regulator
C7M31_RS06190	COG1012	belongs to the aldehyde dehydrogenase family
C7M31_RS06190	COG1454	alcohol dehydrogenase
C7M31_RS06200	COG1695	Transcriptional regulator
C7M31_RS06205	COG3479	Phenolic acid decarboxylase
C7M31_RS06220	COG1307	EDD domain protein, DegV family
C7M31_RS06265	COG0445	tRNA wobble uridine modification
C7M31_RS06270	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
C7M31_RS06275	COG1847	R3H domain protein
C7M31_RS06285	COG4166	transmembrane transport
C7M31_RS06290	COG0706	membrane insertase activity
C7M31_RS06295	COG0594	ribonuclease P activity
C7M31_RS06300	COG0230	Belongs to the bacterial ribosomal protein bL34 family
C7M31_RS06305	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
C7M31_RS06310	COG0592	DNA-directed DNA polymerase activity
C7M31_RS06315	COG2501	S4 domain
C7M31_RS06320	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
C7M31_RS06325	COG0187	DNA topoisomerase II activity
C7M31_RS06335	COG0360	Binds together with S18 to 16S ribosomal RNA
C7M31_RS06340	COG0629	single-stranded DNA binding
C7M31_RS06345	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
C7M31_RS06355	COG0359	binds to the 23S rRNA
C7M31_RS06360	COG0305	Participates in initiation and elongation during chromosome replication
C7M31_RS06365	COG2814	Major facilitator Superfamily
C7M31_RS06370	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
C7M31_RS06375	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
C7M31_RS06380	COG4166	transmembrane transport
C7M31_RS06385	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
C7M31_RS06390	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
C7M31_RS06395	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
C7M31_RS06400	COG0297	glycogen (starch) synthase activity
C7M31_RS06405	COG0058	SHG alpha-glucan phosphorylase activity
C7M31_RS06410	COG3103	Sh3 type 3 domain protein
C7M31_RS06410	COG0366	Alpha amylase catalytic
C7M31_RS06420	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
C7M31_RS06425	COG1554	hydrolase, family 65, central catalytic
C7M31_RS06435	COG1278	Cold shock
C7M31_RS06450	COG0745	RESPONSE REGULATOR receiver
C7M31_RS06455	COG5002	protein histidine kinase activity
C7M31_RS06465	COG4853	Protein conserved in bacteria
C7M31_RS06470	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
C7M31_RS06475	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
C7M31_RS06480	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
C7M31_RS06540	COG1573	uracil-dna glycosylase
C7M31_RS06560	COG1053	succinate dehydrogenase
C7M31_RS06560	COG0431	NADPH-dependent FMN reductase
C7M31_RS06560	COG3976	FMN-binding domain protein
C7M31_RS06565	COG0471	metal ion transport
C7M31_RS06580	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
C7M31_RS06585	COG1028	Short-chain dehydrogenase reductase Sdr
C7M31_RS06595	COG0778	Nitroreductase
C7M31_RS06600	COG2508	Transcriptional regulator
C7M31_RS06605	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
C7M31_RS06610	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
C7M31_RS06620	COG2365	Tyrosine phosphatase family
C7M31_RS06625	COG2368	4-hydroxyphenylacetate
C7M31_RS06645	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
C7M31_RS06680	COG0604	alcohol dehydrogenase
C7M31_RS06695	COG2267	carboxylic ester hydrolase activity
C7M31_RS06710	COG4166	transmembrane transport
C7M31_RS06735	COG1122	ATPase activity
C7M31_RS06740	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
C7M31_RS06745	COG0310	cobalt ion transport
C7M31_RS06750	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
C7M31_RS06755	COG3875	lactate racemase activity
C7M31_RS06760	COG1691	(AIR) carboxylase
C7M31_RS06765	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
C7M31_RS06770	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
C7M31_RS06775	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
C7M31_RS06780	COG1606	tRNA processing
C7M31_RS06790	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
C7M31_RS06795	COG0351	phosphomethylpyrimidine kinase
C7M31_RS06800	COG0352	thiamine-phosphate diphosphorylase activity
C7M31_RS06810	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
C7M31_RS06825	COG1113	amino acid transport
C7M31_RS06835	COG2267	carboxylic ester hydrolase activity
C7M31_RS06840	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
C7M31_RS06850	COG1983	PspC domain protein
C7M31_RS06885	COG0640	Transcriptional regulator
C7M31_RS06890	COG2807	transmembrane transport
C7M31_RS06895	COG0656	L-ascorbic acid biosynthetic process
C7M31_RS06900	COG0667	Aldo Keto reductase
C7M31_RS06930	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
C7M31_RS06935	COG1122	ATPase activity
C7M31_RS06940	COG4720	Psort location CytoplasmicMembrane, score
C7M31_RS06950	COG2188	Transcriptional regulator
C7M31_RS06975	COG1028	Short-chain dehydrogenase reductase Sdr
C7M31_RS06980	COG1131	(ABC) transporter
C7M31_RS06995	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
C7M31_RS07000	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
C7M31_RS07005	COG1309	transcriptional regulator
C7M31_RS07010	COG2376	Dihydroxyacetone kinase
C7M31_RS07015	COG2376	Dihydroxyacetone kinase
C7M31_RS07020	COG1461	Dihydroxyacetone kinase
C7M31_RS07025	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
C7M31_RS07030	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
C7M31_RS07035	COG1609	Transcriptional regulator
C7M31_RS07040	COG1609	Transcriptional regulator
C7M31_RS07045	COG0366	Alpha amylase catalytic
C7M31_RS07050	COG2182	Extracellular solute-binding protein
C7M31_RS07055	COG1175	transmembrane transport
C7M31_RS07060	COG3833	ABC-type maltose transport systems, permease component
C7M31_RS07070	COG0366	Alpha amylase catalytic
C7M31_RS07075	COG3842	ATPase activity
C7M31_RS07155	COG4166	transmembrane transport
C7M31_RS07160	COG4166	transmembrane transport
C7M31_RS07170	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
C7M31_RS07175	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
C7M31_RS07180	COG0406	alpha-ribazole phosphatase activity
C7M31_RS07185	COG0667	Aldo Keto reductase
C7M31_RS07215	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
C7M31_RS07220	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
C7M31_RS07240	COG4172	Belongs to the ABC transporter superfamily
C7M31_RS07250	COG0386	Belongs to the glutathione peroxidase family
C7M31_RS07280	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
C7M31_RS07295	COG0363	glucosamine-6-phosphate deaminase activity
C7M31_RS07305	COG3976	FMN-binding domain protein
C7M31_RS07305	COG1053	succinate dehydrogenase
C7M31_RS07320	COG2213	PTS system mannitol-specific
C7M31_RS07330	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
C7M31_RS07335	COG0246	Mannitol dehydrogenase
C7M31_RS07345	COG3118	belongs to the thioredoxin family
C7M31_RS07375	COG0431	NADPH-dependent FMN reductase
C7M31_RS07380	COG2188	Transcriptional regulator
C7M31_RS07385	COG1943	Transposase
C7M31_RS07390	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C7M31_RS07405	COG3964	amidohydrolase
C7M31_RS07425	COG1045	serine acetyltransferase
C7M31_RS07430	COG0626	cystathionine gamma-synthase activity
C7M31_RS07435	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
C7M31_RS07440	COG0024	Methionine aminopeptidase
C7M31_RS07460	COG2188	Transcriptional regulator
C7M31_RS07465	COG0366	Alpha amylase catalytic
C7M31_RS07470	COG2190	(PTS) system
C7M31_RS07470	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C7M31_RS07470	COG1263	PTS System
C7M31_RS07475	COG1263	PTS System
C7M31_RS07475	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C7M31_RS07475	COG2190	(PTS) system
C7M31_RS07485	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
C7M31_RS07490	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
C7M31_RS07495	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
C7M31_RS07505	COG0163	prenyltransferase activity
C7M31_RS07515	COG1959	2 iron, 2 sulfur cluster binding
C7M31_RS07520	COG1309	transcriptional regulator
C7M31_RS07525	COG1914	H( )-stimulated, divalent metal cation uptake system
C7M31_RS07555	COG5002	protein histidine kinase activity
C7M31_RS07560	COG0745	RESPONSE REGULATOR receiver
C7M31_RS07570	COG1737	Transcriptional regulator
C7M31_RS07575	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C7M31_RS07590	COG1316	TRANSCRIPTIONal
C7M31_RS07595	COG0277	FAD linked oxidase domain protein
C7M31_RS07605	COG2357	RelA SpoT domain protein
C7M31_RS07615	COG1033	growth of symbiont in host cell
C7M31_RS07615	COG2409	Drug exporters of the RND superfamily
C7M31_RS07620	COG2818	Glycosylase
C7M31_RS07630	COG0577	efflux transmembrane transporter activity
C7M31_RS07635	COG1136	(ABC) transporter
C7M31_RS07655	COG0741	lytic transglycosylase activity
C7M31_RS07660	COG3942	CHAP domain
C7M31_RS07660	COG1388	LysM domain
C7M31_RS07690	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
C7M31_RS07700	COG1846	Transcriptional regulator
C7M31_RS07705	COG1252	NADH dehydrogenase
C7M31_RS07745	COG3842	ATPase activity
C7M31_RS07775	COG1725	Transcriptional regulator
C7M31_RS07780	COG1131	(ABC) transporter
C7M31_RS07790	COG1454	alcohol dehydrogenase
C7M31_RS07790	COG1012	belongs to the aldehyde dehydrogenase family
C7M31_RS07825	COG1268	BioY protein
C7M31_RS07840	COG0436	Aminotransferase
C7M31_RS07850	COG1682	transport, permease protein
C7M31_RS07855	COG1134	teichoic acid transport
C7M31_RS07875	COG0004	ammonium transporteR
C7M31_RS07895	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
C7M31_RS07905	COG3759	membrane
C7M31_RS07910	COG1881	PFAM PEBP family protein
C7M31_RS07940	COG0300	oxidoreductase activity
C7M31_RS07955	COG1125	glycine betaine transport
C7M31_RS07965	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
C7M31_RS07975	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
C7M31_RS08095	COG0110	maltose O-acetyltransferase activity
C7M31_RS08105	COG0561	phosphatase activity
C7M31_RS08115	COG0561	phosphatase activity
C7M31_RS08120	COG1114	Component of the transport system for branched-chain amino acids
C7M31_RS08165	COG0463	Glycosyl transferase, family 2
C7M31_RS08190	COG3279	Response regulator of the LytR AlgR family
C7M31_RS08215	COG2274	protein secretion by the type I secretion system
C7M31_RS08250	COG3973	AAA domain
C7M31_RS08255	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
C7M31_RS08260	COG0180	Tryptophanyl-tRNA synthetase
C7M31_RS08265	COG2188	Transcriptional regulator
C7M31_RS08270	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C7M31_RS08285	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C7M31_RS08290	COG2723	6-phospho-beta-galactosidase activity
C7M31_RS08295	COG1940	carbohydrate kinase activity
C7M31_RS08305	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
C7M31_RS08320	COG0248	Ppx GppA phosphatase
C7M31_RS08335	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
C7M31_RS08340	COG1801	Protein of unknown function DUF72
C7M31_RS08350	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
C7M31_RS08350	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
C7M31_RS08355	COG2814	Major facilitator Superfamily
C7M31_RS08380	COG0084	hydrolase, TatD family'
C7M31_RS08385	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
C7M31_RS08390	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
C7M31_RS08395	COG4466	Protein conserved in bacteria
C7M31_RS08400	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
C7M31_RS08405	COG1073	alpha beta
C7M31_RS08410	COG1121	(ABC) transporter
C7M31_RS08415	COG1321	iron dependent repressor
C7M31_RS08415	COG1108	ABC-type Mn2 Zn2 transport systems permease components
C7M31_RS08420	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
C7M31_RS08425	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
C7M31_RS08435	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
C7M31_RS08455	COG1078	dGTPase activity
C7M31_RS08460	COG0095	Lipoate-protein ligase
C7M31_RS08470	COG3343	RNA polymerase activity
C7M31_RS08475	COG0504	CTP synthase activity
C7M31_RS08480	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
C7M31_RS08485	COG0814	amino acid
C7M31_RS08490	COG1760	l-serine dehydratase
C7M31_RS08495	COG1760	l-serine dehydratase
C7M31_RS08510	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
C7M31_RS08515	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
C7M31_RS08520	COG0254	rRNA binding
C7M31_RS08535	COG3764	Sortase (surface protein transpeptidase)
C7M31_RS08540	COG1704	LemA family
C7M31_RS08545	COG0501	Belongs to the peptidase M48B family
C7M31_RS08555	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
C7M31_RS08565	COG0736	holo-[acyl-carrier-protein] synthase activity
C7M31_RS08570	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
C7M31_RS08575	COG2337	Toxic component of a toxin-antitoxin (TA) module
C7M31_RS08580	COG3158	transport of potassium into the cell
C7M31_RS08585	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
C7M31_RS08590	COG0505	Belongs to the CarA family
C7M31_RS08595	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
C7M31_RS08600	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
C7M31_RS08605	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
C7M31_RS08610	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
C7M31_RS08615	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
C7M31_RS08635	COG0039	L-malate dehydrogenase activity
C7M31_RS08640	COG0193	aminoacyl-tRNA hydrolase activity
C7M31_RS08645	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
C7M31_RS08650	COG2244	polysaccharide biosynthetic process
C7M31_RS08655	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
C7M31_RS08665	COG1098	S1 RNA binding domain
C7M31_RS08670	COG0037	tRNA processing
C7M31_RS08685	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
C7M31_RS08690	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
C7M31_RS08695	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
C7M31_RS08740	COG3104	oligopeptide transport
C7M31_RS08785	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
C7M31_RS08805	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
C7M31_RS08810	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
C7M31_RS08825	COG2183	response to ionizing radiation
C7M31_RS08830	COG3091	SprT-like family
C7M31_RS08835	COG0460	homoserine dehydrogenase
C7M31_RS08840	COG0083	homoserine kinase activity
C7M31_RS08875	COG3715	PTS system
C7M31_RS08880	COG3716	PTS system mannose fructose sorbose family IID component
C7M31_RS08890	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
C7M31_RS08890	COG3933	PFAM sigma-54 factor interaction domain-containing protein
C7M31_RS08895	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C7M31_RS08895	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
C7M31_RS08900	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C7M31_RS08900	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
C7M31_RS08905	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
C7M31_RS08915	COG0439	Biotin carboxylase
C7M31_RS08925	COG0825	malonyl-CoA metabolic process
C7M31_RS08930	COG1316	TRANSCRIPTIONal
C7M31_RS08940	COG0697	spore germination
C7M31_RS08945	COG0588	phosphoglycerate mutase activity
C7M31_RS08960	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
C7M31_RS08970	COG0756	dUTP diphosphatase activity
C7M31_RS08980	COG4956	integral membrane protein (PIN domain superfamily)
C7M31_RS08985	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
C7M31_RS08990	COG0215	cysteine-tRNA ligase activity
C7M31_RS08995	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
C7M31_RS09000	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
C7M31_RS09015	COG0267	Belongs to the bacterial ribosomal protein bL33 family
C7M31_RS09025	COG0250	Participates in transcription elongation, termination and antitermination
C7M31_RS09035	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
C7M31_RS09040	COG0081	regulation of translation
C7M31_RS09045	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
C7M31_RS09050	COG0222	ribosome binding
C7M31_RS09070	COG1611	Belongs to the LOG family
C7M31_RS09080	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
C7M31_RS09085	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
C7M31_RS09090	COG2813	Specifically methylates the guanine in position
C7M31_RS09105	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
C7M31_RS09110	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
C7M31_RS09115	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
C7M31_RS09125	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
C7M31_RS09130	COG3870	Protein conserved in bacteria
C7M31_RS09135	COG0470	DNA polymerase III
C7M31_RS09140	COG4467	Involved in initiation control of chromosome replication
C7M31_RS09155	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
C7M31_RS09160	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
C7M31_RS09165	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
C7M31_RS09170	COG3639	organic phosphonate transmembrane transporter activity
C7M31_RS09180	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
C7M31_RS09190	COG1214	PFAM Peptidase M22, glycoprotease
C7M31_RS09195	COG0456	acetyltransferase
C7M31_RS09200	COG0456	acetyltransferase
C7M31_RS09205	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
C7M31_RS09210	COG0488	(ABC) transporter
C7M31_RS09215	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
C7M31_RS09225	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
C7M31_RS09230	COG0459	protein refolding
C7M31_RS09235	COG0531	amino acid
C7M31_RS09240	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
C7M31_RS09245	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
C7M31_RS09250	COG1739	Uncharacterized protein family UPF0029
C7M31_RS09255	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
C7M31_RS09270	COG0653	protein targeting
C7M31_RS09285	COG0745	RESPONSE REGULATOR receiver
C7M31_RS09290	COG5002	protein histidine kinase activity
C7M31_RS09295	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
C7M31_RS09300	COG0573	inorganic phosphate transmembrane transporter activity
C7M31_RS09305	COG0581	inorganic phosphate transmembrane transporter activity
C7M31_RS09310	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
C7M31_RS09315	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
C7M31_RS09320	COG0704	Plays a role in the regulation of phosphate uptake
C7M31_RS09325	COG1983	PspC domain protein
C7M31_RS09330	COG1950	PFAM Membrane protein of
C7M31_RS09335	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
C7M31_RS09340	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
C7M31_RS09345	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
C7M31_RS09360	COG0446	pyridine nucleotide-disulphide oxidoreductase
C7M31_RS09365	COG0492	ferredoxin-NADP+ reductase activity
C7M31_RS09370	COG2323	membrane
C7M31_RS09380	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
C7M31_RS09390	COG0446	pyridine nucleotide-disulphide oxidoreductase
C7M31_RS09400	COG2814	Major facilitator Superfamily
C7M31_RS09410	COG0556	nucleotide-excision repair
C7M31_RS09415	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
C7M31_RS09420	COG1854	S-ribosylhomocysteine lyase activity
C7M31_RS09425	COG0137	argininosuccinate synthase activity
C7M31_RS09430	COG0165	Argininosuccinate lyase
C7M31_RS09440	COG1660	Displays ATPase and GTPase activities
C7M31_RS09445	COG0391	Required for morphogenesis under gluconeogenic growth conditions
C7M31_RS09450	COG1481	regulation of sporulation
C7M31_RS09460	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
C7M31_RS09465	COG0740	serine-type endopeptidase activity
C7M31_RS09475	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
C7M31_RS09480	COG2390	Transcriptional regulator
C7M31_RS09490	COG0126	phosphoglycerate kinase activity
C7M31_RS09495	COG0149	triose-phosphate isomerase activity
C7M31_RS09500	COG0148	phosphopyruvate hydratase activity
C7M31_RS09515	COG0038	chloride channel
C7M31_RS09520	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
C7M31_RS09530	COG0557	exoribonuclease II activity
C7M31_RS09535	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
C7M31_RS09550	COG0765	amino acid transport
C7M31_RS09555	COG1126	abc transporter atp-binding protein
C7M31_RS09565	COG0561	phosphatase activity
C7M31_RS09570	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
C7M31_RS09575	COG0280	phosphate acetyltransferase
C7M31_RS09580	COG0802	atpase or kinase
C7M31_RS09595	COG0708	Exodeoxyribonuclease III
C7M31_RS09605	COG0812	UDP-N-acetylmuramate dehydrogenase activity
C7M31_RS09610	COG0025	NhaP-type Na H and K H
C7M31_RS09635	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
C7M31_RS09640	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
C7M31_RS09650	COG0561	phosphatase activity
C7M31_RS09660	COG2017	converts alpha-aldose to the beta-anomer
C7M31_RS09675	COG0778	Nitroreductase
C7M31_RS09680	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
C7M31_RS09695	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
C7M31_RS09710	COG1393	Belongs to the ArsC family
C7M31_RS09725	COG0477	Major facilitator Superfamily
C7M31_RS09730	COG0248	Ppx GppA phosphatase
C7M31_RS09730	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
C7M31_RS09735	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
C7M31_RS09745	COG3475	LICD family
C7M31_RS09760	COG2252	PERMEase
C7M31_RS09765	COG0028	Belongs to the TPP enzyme family
C7M31_RS09770	COG0196	riboflavin kinase activity
C7M31_RS09775	COG0028	Belongs to the TPP enzyme family
C7M31_RS09780	COG2267	carboxylic ester hydrolase activity
C7M31_RS09790	COG2755	lipolytic protein G-D-S-L family
C7M31_RS09790	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
C7M31_RS09795	COG2936	dipeptidyl-peptidase activity
C7M31_RS09810	COG0531	amino acid
C7M31_RS09835	COG0194	GDP metabolic process
C7M31_RS09840	COG0735	belongs to the Fur family
C7M31_RS09855	COG0546	phosphoglycolate phosphatase activity
C7M31_RS09860	COG0436	Aminotransferase
C7M31_RS09865	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
C7M31_RS09880	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C7M31_RS09885	COG0765	amino acid transport
C7M31_RS09890	COG0765	amino acid transport
C7M31_RS09895	COG2190	(PTS) system
C7M31_RS09895	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C7M31_RS09895	COG1263	PTS System
C7M31_RS09905	COG1263	PTS System
C7M31_RS09905	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C7M31_RS09910	COG3394	polysaccharide catabolic process
C7M31_RS09915	COG0531	amino acid
C7M31_RS09920	COG1846	Transcriptional regulator
C7M31_RS09950	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
C7M31_RS09960	COG2076	Multidrug Resistance protein
C7M31_RS09975	COG0588	phosphoglycerate mutase activity
C7M31_RS09980	COG0569	domain protein
C7M31_RS09980	COG0475	glutathione-regulated potassium exporter activity
C7M31_RS09985	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
C7M31_RS09985	COG0456	acetyltransferase
C7M31_RS09990	COG0586	Pfam SNARE associated Golgi protein
C7M31_RS09995	COG3973	AAA domain
C7M31_RS10000	COG2070	2-Nitropropane dioxygenase
C7M31_RS10005	COG1072	(Pantothenic acid kinase))
C7M31_RS10010	COG0519	Catalyzes the synthesis of GMP from XMP
C7M31_RS10010	COG0518	GMP synthase (glutamine-hydrolyzing) activity
C7M31_RS10020	COG1396	sequence-specific DNA binding
C7M31_RS10030	COG1266	CAAX protease self-immunity
C7M31_RS10035	COG1733	regulation of RNA biosynthetic process
C7M31_RS10040	COG2814	Major facilitator Superfamily
C7M31_RS10055	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
C7M31_RS10055	COG2755	lipolytic protein G-D-S-L family
C7M31_RS10060	COG2261	transglycosylase associated protein
C7M31_RS10075	COG1302	Protein conserved in bacteria
C7M31_RS10105	COG0308	aminopeptidase N
C7M31_RS10110	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
C7M31_RS10135	COG0732	type I restriction modification DNA specificity domain
C7M31_RS10155	COG0572	uridine kinase
C7M31_RS10170	COG0583	DNA-binding transcription factor activity
C7M31_RS10175	COG1053	succinate dehydrogenase
C7M31_RS10185	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
C7M31_RS10190	COG0017	Asparaginyl-tRNA synthetase
C7M31_RS10195	COG2502	aspartate--ammonia ligase
C7M31_RS10200	COG4690	dipeptidase activity
C7M31_RS10220	COG0514	ATP-dependent DNA helicase (RecQ)
C7M31_RS10225	COG0564	pseudouridine synthase activity
C7M31_RS10230	COG0640	Transcriptional regulator
C7M31_RS10265	COG2706	6-phosphogluconolactonase activity
C7M31_RS10270	COG4948	Mandelate Racemase Muconate Lactonizing
C7M31_RS10275	COG2610	gluconate transmembrane transporter activity
C7M31_RS10285	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
C7M31_RS10290	COG0583	DNA-binding transcription factor activity
C7M31_RS10315	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
C7M31_RS10320	COG0527	aspartate kinase activity
C7M31_RS10325	COG0367	asparagine synthase
C7M31_RS10365	COG2814	Major facilitator Superfamily
C7M31_RS10385	COG1278	Cold shock
C7M31_RS10390	COG2966	Psort location CytoplasmicMembrane, score
C7M31_RS10400	COG1316	TRANSCRIPTIONal
C7M31_RS10420	COG1959	2 iron, 2 sulfur cluster binding
C7M31_RS10425	COG0028	Belongs to the TPP enzyme family
C7M31_RS10430	COG0833	amino acid
C7M31_RS10440	COG1428	Deoxynucleoside kinase
C7M31_RS10445	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
C7M31_RS10485	COG4463	regulation of RNA biosynthetic process
C7M31_RS10490	COG0542	response to heat
C7M31_RS10500	COG0085	RNA polymerase activity
C7M31_RS10505	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
C7M31_RS10510	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
C7M31_RS10515	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
C7M31_RS10520	COG0049	tRNA binding
C7M31_RS10525	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
C7M31_RS10530	COG0051	transcription antitermination factor activity, RNA binding
C7M31_RS10535	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
C7M31_RS10540	COG0088	Forms part of the polypeptide exit tunnel
C7M31_RS10545	COG0089	rRNA binding
C7M31_RS10550	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
C7M31_RS10555	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
C7M31_RS10560	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
C7M31_RS10565	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
C7M31_RS10570	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
C7M31_RS10575	COG0255	Belongs to the universal ribosomal protein uL29 family
C7M31_RS10580	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
C7M31_RS10585	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
C7M31_RS10590	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
C7M31_RS10595	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
C7M31_RS10600	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
C7M31_RS10605	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
C7M31_RS10610	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
C7M31_RS10615	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
C7M31_RS10620	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
C7M31_RS10625	COG1841	ribosomal large subunit assembly
C7M31_RS10630	COG0200	Binds to the 23S rRNA
C7M31_RS10640	COG0563	adenylate kinase activity
C7M31_RS10645	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
C7M31_RS10650	COG0257	Belongs to the bacterial ribosomal protein bL36 family
C7M31_RS10655	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
C7M31_RS10660	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
C7M31_RS10665	COG0202	RNA polymerase activity
C7M31_RS10670	COG0203	ribosomal protein L17
C7M31_RS10695	COG4939	FMN-binding domain protein
C7M31_RS10705	COG1122	ATPase activity
C7M31_RS10710	COG1122	ATPase activity
C7M31_RS10720	COG0101	tRNA pseudouridine synthase activity
C7M31_RS10725	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
C7M31_RS10730	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
C7M31_RS10750	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
C7M31_RS10755	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
C7M31_RS10760	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
C7M31_RS10765	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
C7M31_RS10770	COG0471	metal ion transport
C7M31_RS10775	COG2151	metal-sulfur cluster biosynthetic enzyme
C7M31_RS10785	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
C7M31_RS10790	COG1917	Cupin 2, conserved barrel domain protein
C7M31_RS10790	COG4977	sequence-specific DNA binding
C7M31_RS10795	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
C7M31_RS10800	COG1121	(ABC) transporter
C7M31_RS10805	COG1108	ABC-type Mn2 Zn2 transport systems permease components
C7M31_RS10810	COG0803	Belongs to the bacterial solute-binding protein 9 family
C7M31_RS10820	COG0039	L-malate dehydrogenase activity
C7M31_RS10825	COG0471	metal ion transport
C7M31_RS10845	COG3052	prosthetic group binding
C7M31_RS10860	COG2826	transposase and inactivated derivatives, IS30 family
C7M31_RS10875	COG0114	fumarate hydratase activity
C7M31_RS10880	COG1053	succinate dehydrogenase
C7M31_RS10890	COG0583	DNA-binding transcription factor activity
C7M31_RS10895	COG0583	DNA-binding transcription factor activity
C7M31_RS10900	COG0281	malic enzyme
C7M31_RS10910	COG0531	amino acid
C7M31_RS10915	COG4684	Psort location CytoplasmicMembrane, score
C7M31_RS10930	COG1271	oxidase subunit
C7M31_RS10935	COG1294	oxidase, subunit
C7M31_RS10940	COG4988	ABC transporter
C7M31_RS10945	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
C7M31_RS10955	COG0142	geranyltranstransferase activity
C7M31_RS10970	COG1705	Flagellar rod assembly protein muramidase FlgJ
C7M31_RS10975	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
C7M31_RS10980	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
C7M31_RS10985	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
C7M31_RS10995	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
C7M31_RS11000	COG4851	CamS sex pheromone cAM373 precursor
C7M31_RS11005	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
C7M31_RS11010	COG0154	amidase activity
C7M31_RS11015	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
C7M31_RS11020	COG1597	lipid kinase activity
C7M31_RS11025	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
C7M31_RS11040	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C7M31_RS11050	COG1737	Transcriptional regulator
C7M31_RS11065	COG1278	Cold shock
C7M31_RS11070	COG0673	inositol 2-dehydrogenase activity
C7M31_RS11075	COG0513	Belongs to the DEAD box helicase family
C7M31_RS11090	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C7M31_RS11120	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
C7M31_RS11130	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
C7M31_RS11140	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
C7M31_RS11145	COG0562	UDP-galactopyranose mutase
C7M31_RS11170	COG1442	glycosyl transferase family 8
C7M31_RS11170	COG1216	Glycosyl transferase, family 2
C7M31_RS11180	COG0438	transferase activity, transferring glycosyl groups
C7M31_RS11200	COG1088	dTDP-glucose 4,6-dehydratase activity
C7M31_RS11205	COG0582	viral genome integration into host DNA
C7M31_RS11215	COG0489	protein tyrosine kinase activity
C7M31_RS11220	COG4464	protein tyrosine phosphatase activity
C7M31_RS11230	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
C7M31_RS11250	COG1215	transferase activity, transferring glycosyl groups
C7M31_RS11255	COG5039	Polysaccharide pyruvyl transferase
C7M31_RS11285	COG0210	DNA helicase
C7M31_RS11295	COG4974	Belongs to the 'phage' integrase family
C7M31_RS11400	COG0562	UDP-galactopyranose mutase
C7M31_RS11445	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
C7M31_RS11480	COG2137	regulation of response to DNA damage stimulus
C7M31_RS11485	COG3557	Belongs to the UPF0374 family
C7M31_RS11505	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
C7M31_RS11515	COG0628	permease
C7M31_RS11520	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
C7M31_RS11525	COG2610	gluconate transmembrane transporter activity
C7M31_RS11530	COG1070	Carbohydrate kinase
C7M31_RS11535	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
C7M31_RS11540	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
C7M31_RS11545	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
C7M31_RS11575	COG4166	transmembrane transport
C7M31_RS11580	COG0601	transmembrane transport
C7M31_RS11585	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
C7M31_RS11590	COG0444	Belongs to the ABC transporter superfamily
C7M31_RS11595	COG4608	Belongs to the ABC transporter superfamily
C7M31_RS11605	COG0582	viral genome integration into host DNA
C7M31_RS11610	COG0542	response to heat
C7M31_RS11630	COG0438	transferase activity, transferring glycosyl groups
C7M31_RS11635	COG0438	transferase activity, transferring glycosyl groups
C7M31_RS11645	COG1686	Belongs to the peptidase S11 family
C7M31_RS11650	COG0436	Aminotransferase
C7M31_RS11655	COG4703	Protein of unknown function (DUF1797)
C7M31_RS11660	COG1368	sulfuric ester hydrolase activity
C7M31_RS11745	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
C7M31_RS11765	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
C7M31_RS11780	COG0833	amino acid
C7M31_RS11785	COG2040	homocysteine
C7M31_RS11790	COG0438	transferase activity, transferring glycosyl groups
C7M31_RS11800	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
C7M31_RS11805	COG0477	Major facilitator Superfamily
C7M31_RS11820	COG0438	transferase activity, transferring glycosyl groups
C7M31_RS11840	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
C7M31_RS11850	COG0495	leucyl-tRNA aminoacylation
C7M31_RS11855	COG2244	polysaccharide biosynthetic process
C7M31_RS11860	COG1187	pseudouridine synthase activity
C7M31_RS11865	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
C7M31_RS11870	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
C7M31_RS11880	COG3842	ATPase activity
C7M31_RS11885	COG1175	transmembrane transport
C7M31_RS11890	COG0395	ABC-type sugar transport system, permease component
C7M31_RS11900	COG0584	glycerophosphoryl diester phosphodiesterase
C7M31_RS11905	COG1428	Deoxynucleoside kinase
C7M31_RS11910	COG1970	mechanosensitive ion channel activity
C7M31_RS11915	COG1511	domain protein
C7M31_RS11915	COG1511	domain protein
C7M31_RS11945	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
C7M31_RS11950	COG0789	Transcriptional regulator
C7M31_RS11965	COG0561	phosphatase activity
C7M31_RS11985	COG3279	Response regulator of the LytR AlgR family
C7M31_RS12005	COG1846	Transcriptional regulator
C7M31_RS12020	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
C7M31_RS12060	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
C7M31_RS12060	COG0646	methionine synthase
C7M31_RS12065	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
C7M31_RS12075	COG2046	Belongs to the sulfate adenylyltransferase family
C7M31_RS12080	COG0529	Catalyzes the synthesis of activated sulfate
C7M31_RS12085	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
C7M31_RS12095	COG3273	potassium ion transport
C7M31_RS12095	COG0471	metal ion transport
C7M31_RS12100	COG0534	Mate efflux family protein
C7M31_RS12120	COG2153	protein acetylation
C7M31_RS12125	COG0018	arginyl-trna synthetase
C7M31_RS12135	COG0577	efflux transmembrane transporter activity
C7M31_RS12135	COG1136	(ABC) transporter
C7M31_RS12155	COG1447	Phosphotransferase system cellobiose-specific component IIA
C7M31_RS12160	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C7M31_RS12165	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C7M31_RS12170	COG2723	6-phospho-beta-galactosidase activity
C7M31_RS12180	COG1376	ErfK ybiS ycfS ynhG family protein
C7M31_RS12190	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
C7M31_RS12195	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C7M31_RS12205	COG0436	Aminotransferase
C7M31_RS12210	COG1438	arginine binding
C7M31_RS12220	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
C7M31_RS12225	COG3679	Belongs to the UPF0342 family
C7M31_RS12230	COG0420	3'-5' exonuclease activity
C7M31_RS12235	COG4717	serine-type aminopeptidase activity
C7M31_RS12240	COG3481	metal-dependent phosphohydrolase, HD sub domain
C7M31_RS12255	COG0583	DNA-binding transcription factor activity
C7M31_RS12265	COG1053	succinate dehydrogenase
C7M31_RS12265	COG0431	NADPH-dependent FMN reductase
C7M31_RS12265	COG3976	FMN-binding domain protein
C7M31_RS12305	COG2217	Heavy metal translocating P-type atpase
C7M31_RS12310	COG0148	phosphopyruvate hydratase activity
C7M31_RS12320	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
C7M31_RS12325	COG0463	Glycosyl transferase, family 2
C7M31_RS12345	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
C7M31_RS12345	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
C7M31_RS12350	COG0307	riboflavin synthase, alpha
C7M31_RS12355	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
C7M31_RS12355	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
C7M31_RS12360	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
C7M31_RS12375	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
C7M31_RS12385	COG0446	pyridine nucleotide-disulphide oxidoreductase
C7M31_RS12415	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
C7M31_RS12425	COG0537	adenosine 5'-monophosphoramidase activity
C7M31_RS12430	COG1131	(ABC) transporter
C7M31_RS12435	COG4473	ABC transporter
C7M31_RS12440	COG0510	thiamine kinase activity
C7M31_RS12445	COG0220	tRNA (guanine-N7-)-methyltransferase activity
C7M31_RS12455	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
C7M31_RS12460	COG1674	ftsk spoiiie
C7M31_RS12465	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
C7M31_RS12490	COG0719	Fe-S assembly protein
C7M31_RS12495	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
C7M31_RS12505	COG0719	Fe-S assembly protein
C7M31_RS12515	COG1120	ATPase activity
C7M31_RS12525	COG0716	FMN binding
C7M31_RS12540	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
C7M31_RS12545	COG2223	nitrite transmembrane transporter activity
C7M31_RS12550	COG2151	metal-sulfur cluster biosynthetic enzyme
C7M31_RS12575	COG2197	response regulator
C7M31_RS12600	COG0315	cyclic pyranopterin monophosphate synthase activity
C7M31_RS12605	COG1763	Mo-molybdopterin cofactor biosynthetic process
C7M31_RS12610	COG0303	'Molybdopterin
C7M31_RS12620	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
C7M31_RS12625	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
C7M31_RS12630	COG1140	nitrate reductase beta subunit
C7M31_RS12640	COG2181	nitrate reductase activity
C7M31_RS12660	COG3655	Transcriptional regulator
C7M31_RS12670	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
C7M31_RS12670	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
C7M31_RS12675	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
C7M31_RS12680	COG0237	dephospho-CoA kinase activity
C7M31_RS12685	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
C7M31_RS12690	COG3611	Membrane attachment protein
C7M31_RS12695	COG1484	DNA-dependent DNA replication
C7M31_RS12700	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
C7M31_RS12705	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
C7M31_RS12710	COG0291	Belongs to the bacterial ribosomal protein bL35 family
C7M31_RS12715	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
C7M31_RS12725	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
C7M31_RS12730	COG0604	alcohol dehydrogenase
C7M31_RS12735	COG1733	regulation of RNA biosynthetic process
C7M31_RS12745	COG1215	transferase activity, transferring glycosyl groups
C7M31_RS12760	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
C7M31_RS12765	COG1534	Rna-binding protein
C7M31_RS12770	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
C7M31_RS12775	COG1713	HD superfamily hydrolase involved in NAD metabolism
C7M31_RS12780	COG0799	negative regulation of ribosome biogenesis
C7M31_RS12785	COG2226	methyltransferase
C7M31_RS12790	COG1323	Belongs to the UPF0348 family
C7M31_RS12800	COG0333	Belongs to the bacterial ribosomal protein bL32 family
C7M31_RS12815	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
C7M31_RS12820	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
C7M31_RS12825	COG0745	RESPONSE REGULATOR receiver
C7M31_RS12830	COG5002	protein histidine kinase activity
C7M31_RS12840	COG0419	ATPase involved in DNA repair
C7M31_RS12855	COG0706	membrane insertase activity
C7M31_RS12860	COG1254	Belongs to the acylphosphatase family
C7M31_RS12865	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
C7M31_RS12875	COG1733	regulation of RNA biosynthetic process
C7M31_RS12880	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
C7M31_RS12885	COG0072	phenylalanine-tRNA ligase activity
C7M31_RS12885	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
C7M31_RS12890	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
C7M31_RS12895	COG0572	uridine kinase
C7M31_RS12900	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
C7M31_RS12915	COG4841	protein insertion into membrane
C7M31_RS12925	COG0768	penicillin binding
C7M31_RS12930	COG0267	Belongs to the bacterial ribosomal protein bL33 family
C7M31_RS12935	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
C7M31_RS12940	COG0705	Rhomboid family
C7M31_RS12940	COG0457	Tetratricopeptide repeat
C7M31_RS12950	COG1940	carbohydrate kinase activity
C7M31_RS12970	COG0584	glycerophosphoryl diester phosphodiesterase
C7M31_RS12975	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
C7M31_RS12980	COG0789	Transcriptional regulator
C7M31_RS13030	COG0261	This protein binds to 23S rRNA in the presence of protein L20
C7M31_RS13040	COG0211	Belongs to the bacterial ribosomal protein bL27 family
C7M31_RS13045	COG0006	proline dipeptidase activity
C7M31_RS13050	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
C7M31_RS13055	COG1302	Protein conserved in bacteria
C7M31_RS13060	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
C7M31_RS13065	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
C7M31_RS13070	COG1570	exodeoxyribonuclease VII activity
C7M31_RS13075	COG1722	exodeoxyribonuclease VII activity
C7M31_RS13080	COG0142	geranyltranstransferase activity
C7M31_RS13085	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
C7M31_RS13090	COG1438	arginine binding
C7M31_RS13095	COG0497	DNA recombination
C7M31_RS13110	COG1732	Glycine betaine
C7M31_RS13115	COG1174	glycine betaine transport
C7M31_RS13125	COG0194	GDP metabolic process
C7M31_RS13130	COG1758	RNA polymerase activity
C7M31_RS13135	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
C7M31_RS13140	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
C7M31_RS13145	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
C7M31_RS13150	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
C7M31_RS13150	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
C7M31_RS13155	COG0631	protein serine/threonine phosphatase activity
C7M31_RS13160	COG0515	serine threonine protein kinase
C7M31_RS13160	COG2815	serine threonine protein kinase
C7M31_RS13165	COG1162	GTPase activity
C7M31_RS13170	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
C7M31_RS13175	COG1564	THIamine pyrophosphokinase
C7M31_RS13185	COG0227	Belongs to the bacterial ribosomal protein bL28 family
C7M31_RS13190	COG1302	Protein conserved in bacteria
C7M31_RS13195	COG1461	Dihydroxyacetone kinase
C7M31_RS13200	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
C7M31_RS13205	COG0416	fatty acid biosynthetic process
C7M31_RS13210	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
C7M31_RS13215	COG0571	ribonuclease III activity
C7M31_RS13220	COG1196	nuclear chromosome segregation
C7M31_RS13225	COG0552	protein localization to endoplasmic reticulum
C7M31_RS13230	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
C7M31_RS13235	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
C7M31_RS13240	COG0228	four-way junction DNA binding
C7M31_RS13245	COG1837	Belongs to the UPF0109 family
C7M31_RS13250	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
C7M31_RS13255	COG0336	Belongs to the RNA methyltransferase TrmD family
C7M31_RS13260	COG0335	large ribosomal subunit rRNA binding
C7M31_RS13295	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
C7M31_RS13295	COG0512	Glutamine amidotransferase of anthranilate synthase
C7M31_RS13300	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
C7M31_RS13305	COG0134	indole-3-glycerol-phosphate synthase activity
C7M31_RS13310	COG0135	phosphoribosylanthranilate isomerase activity
C7M31_RS13315	COG0133	tryptophan synthase activity
C7M31_RS13320	COG0159	tryptophan synthase activity
C7M31_RS13335	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
C7M31_RS13350	COG1063	alcohol dehydrogenase
C7M31_RS13360	COG0300	oxidoreductase activity
C7M31_RS13370	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
C7M31_RS13375	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
C7M31_RS13380	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
C7M31_RS13385	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
C7M31_RS13390	COG1028	Short-chain dehydrogenase reductase Sdr
C7M31_RS13395	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
C7M31_RS13410	COG0439	Biotin carboxylase
C7M31_RS13425	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
C7M31_RS13435	COG1811	Na channel or pump
C7M31_RS13440	COG0583	DNA-binding transcription factor activity
C7M31_RS13445	COG1607	acyl-coa hydrolase
C7M31_RS13450	COG1162	GTPase activity
C7M31_RS13460	COG0477	Major facilitator Superfamily
C7M31_RS13480	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
C7M31_RS13485	COG3397	chitin binding
C7M31_RS13505	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
C7M31_RS13515	COG3152	Membrane
C7M31_RS13520	COG1597	lipid kinase activity
C7M31_RS13535	COG2261	transglycosylase associated protein
C7M31_RS13540	COG3237	CsbD-like
C7M31_RS13555	COG1942	4-Oxalocrotonate Tautomerase
C7M31_RS13590	COG0531	amino acid
C7M31_RS13595	COG0561	phosphatase activity
C7M31_RS13600	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
C7M31_RS13600	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
C7M31_RS13620	COG2017	converts alpha-aldose to the beta-anomer
C7M31_RS13625	COG1304	FMN binding
C7M31_RS13650	COG1199	ATP-dependent helicase activity
C7M31_RS13650	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
C7M31_RS13665	COG0017	Asparaginyl-tRNA synthetase
C7M31_RS13680	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
C7M31_RS13685	COG2011	ABC-type metal ion transport system permease component
C7M31_RS13690	COG1464	Belongs to the NlpA lipoprotein family
C7M31_RS13700	COG1177	transmembrane transport
C7M31_RS13705	COG1840	ABC-type Fe3 transport system, periplasmic component
C7M31_RS13720	COG3331	DNA recombination
C7M31_RS13725	COG4474	Belongs to the UPF0398 family
C7M31_RS13730	COG3599	regulation of cell shape
C7M31_RS13740	COG0116	Belongs to the methyltransferase superfamily
C7M31_RS13745	COG1073	alpha beta
C7M31_RS13755	COG1216	Glycosyl transferase, family 2
C7M31_RS13775	COG1619	proteins homologs of microcin C7 resistance protein MccF
C7M31_RS13800	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
C7M31_RS13815	COG2759	Belongs to the formate--tetrahydrofolate ligase family
C7M31_RS13820	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
C7M31_RS13825	COG0564	pseudouridine synthase activity
C7M31_RS13830	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
C7M31_RS13835	COG0505	Belongs to the CarA family
C7M31_RS13840	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
C7M31_RS13850	COG5646	InterPro IPR014922
C7M31_RS13875	COG1131	(ABC) transporter
C7M31_RS13895	COG1307	EDD domain protein, DegV family
C7M31_RS13950	COG1113	amino acid transport
C7M31_RS13965	COG1620	l-lactate permease
C7M31_RS13975	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
C7M31_RS13985	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
C7M31_RS14000	COG1846	Transcriptional regulator
C7M31_RS14040	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
C7M31_RS14045	COG1227	inorganic diphosphatase activity
C7M31_RS14050	COG0583	DNA-binding transcription factor activity
C7M31_RS14060	COG0187	DNA topoisomerase II activity
C7M31_RS14065	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
C7M31_RS14075	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
C7M31_RS14080	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
C7M31_RS14085	COG4974	Belongs to the 'phage' integrase family
C7M31_RS14090	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
C7M31_RS14095	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
C7M31_RS14100	COG0758	DNA mediated transformation
C7M31_RS14105	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
C7M31_RS14110	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
C7M31_RS14115	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
C7M31_RS14120	COG0583	DNA-binding transcription factor activity
C7M31_RS14140	COG2814	Major facilitator Superfamily
C7M31_RS14145	COG0793	Belongs to the peptidase S41A family
C7M31_RS14145	COG3409	Peptidoglycan-binding domain 1 protein
C7M31_RS14150	COG4479	Belongs to the UPF0346 family
C7M31_RS14155	COG4698	Protein conserved in bacteria
C7M31_RS14160	COG2755	lipolytic protein G-D-S-L family
C7M31_RS14165	COG1307	EDD domain protein, DegV family
C7M31_RS14170	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
C7M31_RS14175	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
C7M31_RS14180	COG0488	(ABC) transporter
C7M31_RS14190	COG0617	tRNA 3'-terminal CCA addition
C7M31_RS14195	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
C7M31_RS14200	COG0561	phosphatase activity
C7M31_RS14205	COG0457	Tetratricopeptide repeat
C7M31_RS14220	COG1160	GTP binding
C7M31_RS14225	COG0539	negative regulation of cytoplasmic translation
C7M31_RS14230	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
C7M31_RS14240	COG0514	ATP-dependent DNA helicase (RecQ)
C7M31_RS14250	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
C7M31_RS14255	COG1187	pseudouridine synthase activity
C7M31_RS14260	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
C7M31_RS14265	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
C7M31_RS14275	COG4974	Belongs to the 'phage' integrase family
C7M31_RS14280	COG2996	Protein conserved in bacteria
C7M31_RS14295	COG1943	Transposase
C7M31_RS14305	COG0205	6-phosphofructokinase activity
C7M31_RS14310	COG0587	DNA-directed DNA polymerase activity
C7M31_RS14320	COG0542	response to heat
C7M31_RS14330	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
C7M31_RS14335	COG2384	SAM-dependent methyltransferase
C7M31_RS14360	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
C7M31_RS14360	COG0574	Belongs to the PEP-utilizing enzyme family
C7M31_RS14370	COG1846	Transcriptional regulator
C7M31_RS14395	COG0148	phosphopyruvate hydratase activity
C7M31_RS14400	COG0477	Major facilitator Superfamily
C7M31_RS14410	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
C7M31_RS14415	COG0446	pyridine nucleotide-disulphide oxidoreductase
C7M31_RS14420	COG1349	DNA-binding transcription factor activity
C7M31_RS14430	COG1393	Belongs to the ArsC family
C7M31_RS14450	COG0546	phosphoglycolate phosphatase activity
C7M31_RS14480	COG0583	DNA-binding transcription factor activity
C7M31_RS14485	COG0604	alcohol dehydrogenase
C7M31_RS14495	COG0446	pyridine nucleotide-disulphide oxidoreductase
C7M31_RS14500	COG2197	response regulator
C7M31_RS14505	COG4585	Histidine kinase
C7M31_RS14515	COG1131	(ABC) transporter
C7M31_RS14525	COG0519	Catalyzes the synthesis of GMP from XMP
C7M31_RS14570	COG1131	(ABC) transporter
C7M31_RS14575	COG1725	Transcriptional regulator
C7M31_RS14580	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
C7M31_RS14585	COG0358	DNA primase activity
C7M31_RS14590	COG0751	glycine-tRNA ligase activity
C7M31_RS14595	COG0752	glycyl-tRNA synthetase alpha subunit
C7M31_RS14600	COG1381	Involved in DNA repair and RecF pathway recombination
C7M31_RS14605	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
C7M31_RS14610	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
C7M31_RS14615	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
C7M31_RS14620	COG1702	phosphate starvation-inducible protein PhoH
C7M31_RS14625	COG1610	YqeY-like protein
C7M31_RS14630	COG0828	Belongs to the bacterial ribosomal protein bS21 family
C7M31_RS14635	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
C7M31_RS14645	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
C7M31_RS14655	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
C7M31_RS14665	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
C7M31_RS14670	COG0124	histidyl-tRNA synthetase
C7M31_RS14675	COG4991	sh3 domain protein
C7M31_RS14675	COG3103	Sh3 type 3 domain protein
C7M31_RS14675	COG0860	N-Acetylmuramoyl-L-alanine amidase
C7M31_RS14685	COG0546	phosphoglycolate phosphatase activity
C7M31_RS14690	COG1490	D-aminoacyl-tRNA deacylase activity
C7M31_RS14695	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
C7M31_RS14705	COG1385	rRNA (uridine-N3-)-methyltransferase activity
C7M31_RS14710	COG2264	protein methyltransferase activity
C7M31_RS14715	COG2094	Belongs to the DNA glycosylase MPG family
C7M31_RS14730	COG0481	GTPase activity
C7M31_RS14735	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
C7M31_RS14740	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
C7M31_RS14745	COG1696	Membrane protein involved in D-alanine export
C7M31_RS14750	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C7M31_RS14760	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
C7M31_RS14765	COG0484	heat shock protein binding
C7M31_RS14770	COG0443	Heat shock 70 kDa protein
C7M31_RS14775	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
C7M31_RS14780	COG1420	regulation of RNA biosynthetic process
C7M31_RS14785	COG3527	Alpha-acetolactate decarboxylase
C7M31_RS14790	COG0196	riboflavin kinase activity
C7M31_RS14795	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
C7M31_RS14800	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
C7M31_RS14805	COG0287	Prephenate dehydrogenase
C7M31_RS14810	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
C7M31_RS14820	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
C7M31_RS14825	COG0738	Major facilitator superfamily
C7M31_RS14830	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
C7M31_RS14835	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
C7M31_RS14845	COG2740	Nucleic-acid-binding protein implicated in transcription termination
C7M31_RS14850	COG0195	Participates in both transcription termination and antitermination
C7M31_RS14855	COG0779	Required for maturation of 30S ribosomal subunits
C7M31_RS14860	COG2176	DNA-directed DNA polymerase activity
C7M31_RS14865	COG0442	prolyl-tRNA aminoacylation
C7M31_RS14870	COG0750	zinc metalloprotease
C7M31_RS14875	COG4589	Belongs to the CDS family
C7M31_RS14880	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
C7M31_RS14885	COG0233	cytoplasmic translational termination
C7M31_RS14890	COG0528	UMP kinase activity
C7M31_RS14895	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
C7M31_RS14900	COG0052	Belongs to the universal ribosomal protein uS2 family
C7M31_RS14910	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
C7M31_RS14915	COG2827	Endonuclease containing a URI domain
C7M31_RS14920	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
C7M31_RS14925	COG0204	Acyl-transferase
C7M31_RS14930	COG3763	UPF0154 protein
C7M31_RS14935	COG4224	UPF0291 protein
C7M31_RS14940	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
C7M31_RS14955	COG3425	synthase
C7M31_RS14970	COG0463	Glycosyl transferase, family 2
C7M31_RS14980	COG1316	TRANSCRIPTIONal
C7M31_RS14985	COG1116	anion transmembrane transporter activity
C7M31_RS14995	COG0772	Belongs to the SEDS family
C7M31_RS15050	COG5280	Phage tail tape measure protein TP901
C7M31_RS15050	COG3953	SLT domain