ALX04_RS15495 a3d3aff893c106e4541c6681a0bd573a 307 Gene3D G3DSA:3.50.50.60 1 123 5.4E-26 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ALX04_RS15495 a3d3aff893c106e4541c6681a0bd573a 307 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 6 25 1.6E-40 T 28-03-2018 ALX04_RS15495 a3d3aff893c106e4541c6681a0bd573a 307 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 145 163 1.6E-40 T 28-03-2018 ALX04_RS15495 a3d3aff893c106e4541c6681a0bd573a 307 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 230 246 1.6E-40 T 28-03-2018 ALX04_RS15495 a3d3aff893c106e4541c6681a0bd573a 307 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 256 278 1.6E-40 T 28-03-2018 ALX04_RS15495 a3d3aff893c106e4541c6681a0bd573a 307 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 103 121 1.6E-40 T 28-03-2018 ALX04_RS15495 a3d3aff893c106e4541c6681a0bd573a 307 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 4 292 4.5E-53 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ALX04_RS15495 a3d3aff893c106e4541c6681a0bd573a 307 Gene3D G3DSA:3.50.50.60 237 305 5.1E-11 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ALX04_RS15495 a3d3aff893c106e4541c6681a0bd573a 307 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 126 138 5.0E-71 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 ALX04_RS15495 a3d3aff893c106e4541c6681a0bd573a 307 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 38 53 5.0E-71 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 ALX04_RS15495 a3d3aff893c106e4541c6681a0bd573a 307 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 104 112 5.0E-71 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 ALX04_RS15495 a3d3aff893c106e4541c6681a0bd573a 307 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 58 68 5.0E-71 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 ALX04_RS15495 a3d3aff893c106e4541c6681a0bd573a 307 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 5 27 5.0E-71 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 ALX04_RS15495 a3d3aff893c106e4541c6681a0bd573a 307 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 266 284 5.0E-71 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 ALX04_RS15495 a3d3aff893c106e4541c6681a0bd573a 307 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 141 165 5.0E-71 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 ALX04_RS15495 a3d3aff893c106e4541c6681a0bd573a 307 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 232 253 5.0E-71 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 ALX04_RS15495 a3d3aff893c106e4541c6681a0bd573a 307 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 193 209 5.0E-71 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 ALX04_RS15495 a3d3aff893c106e4541c6681a0bd573a 307 SUPERFAMILY SSF51905 2 305 2.09E-57 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ALX04_RS15495 a3d3aff893c106e4541c6681a0bd573a 307 TIGRFAM TIGR01292 TRX_reduct: thioredoxin-disulfide reductase 4 303 5.2E-112 T 28-03-2018 IPR005982 Thioredoxin reductase GO:0004791|GO:0005737|GO:0019430|GO:0055114 KEGG: 00450+1.8.1.9 ALX04_RS15495 a3d3aff893c106e4541c6681a0bd573a 307 ProSitePatterns PS00573 Pyridine nucleotide-disulphide oxidoreductases class-II active site. 133 153 - T 28-03-2018 IPR008255 Pyridine nucleotide-disulphide oxidoreductase, class-II, active site GO:0016491|GO:0055114 ALX04_RS15495 a3d3aff893c106e4541c6681a0bd573a 307 Gene3D G3DSA:3.50.50.60 124 236 4.4E-22 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ALX04_RS05855 bd1843b08a2c91e265f5421cf7ad50a9 461 PIRSF PIRSF006060 1 461 8.9E-56 T 28-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 ALX04_RS05855 bd1843b08a2c91e265f5421cf7ad50a9 461 Pfam PF00324 Amino acid permease 21 448 2.3E-91 T 28-03-2018 IPR004841 Amino acid permease/ SLC12A domain GO:0006810|GO:0016020|GO:0055085 ALX04_RS05855 bd1843b08a2c91e265f5421cf7ad50a9 461 ProSitePatterns PS00218 Amino acid permeases signature. 46 76 - T 28-03-2018 IPR004840 Amino acid permease, conserved site GO:0006865|GO:0016021|GO:0055085 ALX04_RS02565 d73b2f3b027bc872b7d999c1281c22e1 100 PIRSF PIRSF034852 1 97 4.7E-32 T 28-03-2018 IPR008326 Uncharacterised conserved protein UCP034852 ALX04_RS02565 d73b2f3b027bc872b7d999c1281c22e1 100 Gene3D G3DSA:2.60.300.12 1 100 2.6E-9 T 28-03-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 ALX04_RS02565 d73b2f3b027bc872b7d999c1281c22e1 100 SUPERFAMILY SSF89360 1 97 4.45E-12 T 28-03-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 ALX04_RS02730 74a00a59477d11014732ae70b1ffb617 76 Pfam PF02609 Exonuclease VII small subunit 7 58 2.0E-19 T 28-03-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 ALX04_RS02730 74a00a59477d11014732ae70b1ffb617 76 ProDom PD028235 EXONUCLEASE SMALL SUBUNIT VII EXODEOXYRIBONUCLEASE HYDROLASE NUCLEASE PROBABLE VII SIMILAR 1 48 8.0E-20 T 28-03-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 ALX04_RS02730 74a00a59477d11014732ae70b1ffb617 76 PIRSF PIRSF006488 1 76 1.2E-18 T 28-03-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 ALX04_RS02730 74a00a59477d11014732ae70b1ffb617 76 SUPERFAMILY SSF116842 3 71 3.27E-20 T 28-03-2018 ALX04_RS02730 74a00a59477d11014732ae70b1ffb617 76 Hamap MF_00337 Exodeoxyribonuclease 7 small subunit [xseB]. 6 66 14.563 T 28-03-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 ALX04_RS02730 74a00a59477d11014732ae70b1ffb617 76 TIGRFAM TIGR01280 xseB: exodeoxyribonuclease VII, small subunit 6 62 8.0E-23 T 28-03-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 ALX04_RS02730 74a00a59477d11014732ae70b1ffb617 76 Gene3D G3DSA:1.10.287.1040 4 71 3.6E-23 T 28-03-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 ALX04_RS07720 d3e3e4dafb0eeb65016eff110681826c 387 SUPERFAMILY SSF103473 7 381 2.75E-53 T 28-03-2018 IPR020846 Major facilitator superfamily domain ALX04_RS07720 d3e3e4dafb0eeb65016eff110681826c 387 Pfam PF07690 Major Facilitator Superfamily 10 223 3.0E-18 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 ALX04_RS07720 d3e3e4dafb0eeb65016eff110681826c 387 Gene3D G3DSA:1.20.1250.20 2 190 1.9E-25 T 28-03-2018 ALX04_RS07720 d3e3e4dafb0eeb65016eff110681826c 387 Gene3D G3DSA:1.20.1250.20 191 384 2.4E-27 T 28-03-2018 ALX04_RS13520 476e561437d45854636bf97b4e6ff36f 683 TIGRFAM TIGR00398 metG: methionine--tRNA ligase 8 500 4.8E-167 T 28-03-2018 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 ALX04_RS13520 476e561437d45854636bf97b4e6ff36f 683 Gene3D G3DSA:2.40.50.140 573 683 1.3E-27 T 28-03-2018 ALX04_RS13520 476e561437d45854636bf97b4e6ff36f 683 PRINTS PR01041 Methionyl-tRNA synthetase signature 42 56 1.6E-32 T 28-03-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 ALX04_RS13520 476e561437d45854636bf97b4e6ff36f 683 PRINTS PR01041 Methionyl-tRNA synthetase signature 362 373 1.6E-32 T 28-03-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 ALX04_RS13520 476e561437d45854636bf97b4e6ff36f 683 PRINTS PR01041 Methionyl-tRNA synthetase signature 236 247 1.6E-32 T 28-03-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 ALX04_RS13520 476e561437d45854636bf97b4e6ff36f 683 PRINTS PR01041 Methionyl-tRNA synthetase signature 10 23 1.6E-32 T 28-03-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 ALX04_RS13520 476e561437d45854636bf97b4e6ff36f 683 PRINTS PR01041 Methionyl-tRNA synthetase signature 90 101 1.6E-32 T 28-03-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 ALX04_RS13520 476e561437d45854636bf97b4e6ff36f 683 PRINTS PR01041 Methionyl-tRNA synthetase signature 270 285 1.6E-32 T 28-03-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 ALX04_RS13520 476e561437d45854636bf97b4e6ff36f 683 SUPERFAMILY SSF50249 580 681 9.79E-31 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold ALX04_RS13520 476e561437d45854636bf97b4e6ff36f 683 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 17 26 - T 28-03-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 ALX04_RS13520 476e561437d45854636bf97b4e6ff36f 683 Gene3D G3DSA:1.10.730.10 359 525 5.8E-39 T 28-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 ALX04_RS13520 476e561437d45854636bf97b4e6ff36f 683 Hamap MF_01228 Methionine--tRNA ligase [metG]. 4 524 48.909 T 28-03-2018 IPR023457 Methionine-tRNA synthetase, type 2 GO:0004825 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 ALX04_RS13520 476e561437d45854636bf97b4e6ff36f 683 SUPERFAMILY SSF47323 364 593 2.8E-41 T 28-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 ALX04_RS13520 476e561437d45854636bf97b4e6ff36f 683 Pfam PF08264 Anticodon-binding domain of tRNA 400 555 1.8E-6 T 28-03-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0000166|GO:0006418 ALX04_RS13520 476e561437d45854636bf97b4e6ff36f 683 Pfam PF01588 Putative tRNA binding domain 587 680 2.6E-25 T 28-03-2018 IPR002547 tRNA-binding domain GO:0000049 Reactome: R-HSA-379716 ALX04_RS13520 476e561437d45854636bf97b4e6ff36f 683 SUPERFAMILY SSF52374 5 365 9.38E-110 T 28-03-2018 ALX04_RS13520 476e561437d45854636bf97b4e6ff36f 683 Gene3D G3DSA:3.40.50.620 5 358 1.8E-96 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold ALX04_RS13520 476e561437d45854636bf97b4e6ff36f 683 Pfam PF09334 tRNA synthetases class I (M) 8 374 4.4E-113 T 28-03-2018 IPR015413 Methionyl/Leucyl tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0006418 ALX04_RS13520 476e561437d45854636bf97b4e6ff36f 683 TIGRFAM TIGR00399 metG_C_term: methionine--tRNA ligase, beta subunit 550 682 6.1E-39 T 28-03-2018 IPR004495 Methionyl-tRNA synthetase, beta subunit, C-terminal GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 ALX04_RS02500 0ef2d500349beb1aac94f042b1333889 90 SUPERFAMILY SSF54975 2 88 5.67E-24 T 28-03-2018 IPR001792 Acylphosphatase-like domain KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 ALX04_RS02500 0ef2d500349beb1aac94f042b1333889 90 Pfam PF00708 Acylphosphatase 6 88 6.3E-22 T 28-03-2018 IPR001792 Acylphosphatase-like domain KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 ALX04_RS02500 0ef2d500349beb1aac94f042b1333889 90 Gene3D G3DSA:3.30.70.100 1 90 5.6E-23 T 28-03-2018 ALX04_RS15370 bdd9babe47c421f04043aaf8de037475 844 Pfam PF11838 ERAP1-like C-terminal domain 509 815 3.9E-49 T 28-03-2018 IPR024571 ERAP1-like C-terminal domain ALX04_RS15370 bdd9babe47c421f04043aaf8de037475 844 SUPERFAMILY SSF63737 6 188 6.54E-45 T 28-03-2018 ALX04_RS15370 bdd9babe47c421f04043aaf8de037475 844 Pfam PF01433 Peptidase family M1 domain 199 435 2.1E-88 T 28-03-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 ALX04_RS15370 bdd9babe47c421f04043aaf8de037475 844 Gene3D G3DSA:2.60.40.1730 1 188 1.0E-38 T 28-03-2018 ALX04_RS15370 bdd9babe47c421f04043aaf8de037475 844 Gene3D G3DSA:1.10.390.10 273 439 1.4E-50 T 28-03-2018 ALX04_RS15370 bdd9babe47c421f04043aaf8de037475 844 SUPERFAMILY SSF55486 196 446 5.13E-80 T 28-03-2018 ALX04_RS15370 bdd9babe47c421f04043aaf8de037475 844 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 305 317 7.9E-30 T 28-03-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 ALX04_RS15370 bdd9babe47c421f04043aaf8de037475 844 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 126 141 7.9E-30 T 28-03-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 ALX04_RS15370 bdd9babe47c421f04043aaf8de037475 844 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 286 301 7.9E-30 T 28-03-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 ALX04_RS15370 bdd9babe47c421f04043aaf8de037475 844 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 171 186 7.9E-30 T 28-03-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 ALX04_RS15370 bdd9babe47c421f04043aaf8de037475 844 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 250 260 7.9E-30 T 28-03-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 ALX04_RS13320 416072ebbeff1960467597d61e315068 290 SUPERFAMILY SSF46689 229 280 1.25E-13 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 ALX04_RS13320 416072ebbeff1960467597d61e315068 290 SUPERFAMILY SSF51215 20 159 3.4E-12 T 28-03-2018 ALX04_RS13320 416072ebbeff1960467597d61e315068 290 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 230 272 - T 28-03-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 ALX04_RS13320 416072ebbeff1960467597d61e315068 290 Pfam PF12833 Helix-turn-helix domain 199 277 8.9E-23 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 ALX04_RS13320 416072ebbeff1960467597d61e315068 290 Gene3D G3DSA:1.10.10.60 168 229 4.9E-7 T 28-03-2018 ALX04_RS13320 416072ebbeff1960467597d61e315068 290 SMART SM00342 193 276 9.8E-24 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 ALX04_RS13320 416072ebbeff1960467597d61e315068 290 Gene3D G3DSA:2.60.120.280 7 164 4.8E-15 T 28-03-2018 ALX04_RS13320 416072ebbeff1960467597d61e315068 290 Gene3D G3DSA:1.10.10.60 230 288 3.5E-14 T 28-03-2018 ALX04_RS13320 416072ebbeff1960467597d61e315068 290 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 245 260 6.3E-5 T 28-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 ALX04_RS13320 416072ebbeff1960467597d61e315068 290 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 260 276 6.3E-5 T 28-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 ALX04_RS13320 416072ebbeff1960467597d61e315068 290 Pfam PF02311 AraC-like ligand binding domain 23 156 1.9E-7 T 28-03-2018 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 ALX04_RS02590 3e58251b819cc61996533d39bc9238bb 227 SUPERFAMILY SSF144091 9 191 5.49E-42 T 28-03-2018 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 ALX04_RS02590 3e58251b819cc61996533d39bc9238bb 227 Pfam PF01694 Rhomboid family 52 189 1.1E-31 T 28-03-2018 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 ALX04_RS02590 3e58251b819cc61996533d39bc9238bb 227 Gene3D G3DSA:1.20.1540.10 9 189 5.4E-38 T 28-03-2018 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 ALX04_RS12685 8f2c7be911a7e60dcf58bbd5535a12fd 262 TIGRFAM TIGR01528 NMN_trans_PnuC: nicotinamide mononucleotide transporter PnuC 45 231 9.5E-23 T 28-03-2018 IPR006419 Nicotinamide mononucleotide transporter PnuC GO:0016020|GO:0034257|GO:0034258 ALX04_RS12685 8f2c7be911a7e60dcf58bbd5535a12fd 262 Pfam PF04973 Nicotinamide mononucleotide transporter 45 224 3.6E-29 T 28-03-2018 IPR006419 Nicotinamide mononucleotide transporter PnuC GO:0016020|GO:0034257|GO:0034258 ALX04_RS15400 1c62c18f309ecaf1271ef40fc3bac1c5 208 Pfam PF01420 Type I restriction modification DNA specificity domain 24 191 5.0E-11 T 28-03-2018 IPR000055 Restriction endonuclease, type I, HsdS GO:0003677|GO:0006304 ALX04_RS15400 1c62c18f309ecaf1271ef40fc3bac1c5 208 SUPERFAMILY SSF116734 22 191 2.78E-27 T 28-03-2018 ALX04_RS15400 1c62c18f309ecaf1271ef40fc3bac1c5 208 Gene3D G3DSA:3.90.220.20 18 190 1.7E-28 T 28-03-2018 ALX04_RS15725 9b6f796ce3403709e31b897fe4d60b62 457 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 209 442 7.2E-33 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 ALX04_RS15725 9b6f796ce3403709e31b897fe4d60b62 457 SUPERFAMILY SSF88659 289 367 1.0E-11 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 ALX04_RS15725 9b6f796ce3403709e31b897fe4d60b62 457 SUPERFAMILY SSF88659 355 449 2.8E-23 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 ALX04_RS15725 9b6f796ce3403709e31b897fe4d60b62 457 PRINTS PR00046 Major sigma-70 factor signature 414 429 6.5E-26 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 ALX04_RS15725 9b6f796ce3403709e31b897fe4d60b62 457 PRINTS PR00046 Major sigma-70 factor signature 264 272 6.5E-26 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 ALX04_RS15725 9b6f796ce3403709e31b897fe4d60b62 457 PRINTS PR00046 Major sigma-70 factor signature 393 405 6.5E-26 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 ALX04_RS15725 9b6f796ce3403709e31b897fe4d60b62 457 PRINTS PR00046 Major sigma-70 factor signature 240 253 6.5E-26 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 ALX04_RS15725 9b6f796ce3403709e31b897fe4d60b62 457 PRINTS PR00046 Major sigma-70 factor signature 429 440 6.5E-26 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 ALX04_RS15725 9b6f796ce3403709e31b897fe4d60b62 457 Gene3D G3DSA:1.10.10.10 383 454 2.1E-24 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS15725 9b6f796ce3403709e31b897fe4d60b62 457 Pfam PF04545 Sigma-70, region 4 390 442 3.0E-16 T 28-03-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 ALX04_RS15725 9b6f796ce3403709e31b897fe4d60b62 457 Pfam PF06044 Dam-replacing family 70 136 2.4E-16 T 28-03-2018 IPR010324 Dam-replacing ALX04_RS15725 9b6f796ce3403709e31b897fe4d60b62 457 Gene3D G3DSA:1.10.601.10 95 284 2.5E-34 T 28-03-2018 ALX04_RS15725 9b6f796ce3403709e31b897fe4d60b62 457 Pfam PF04542 Sigma-70 region 2 213 284 5.1E-15 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 ALX04_RS15725 9b6f796ce3403709e31b897fe4d60b62 457 SUPERFAMILY SSF88946 181 285 9.58E-32 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 ALX04_RS15725 9b6f796ce3403709e31b897fe4d60b62 457 Gene3D G3DSA:1.10.10.10 285 336 2.9E-13 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS15725 9b6f796ce3403709e31b897fe4d60b62 457 Pfam PF04539 Sigma-70 region 3 295 374 7.0E-10 T 28-03-2018 IPR007624 RNA polymerase sigma-70 region 3 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 ALX04_RS15725 9b6f796ce3403709e31b897fe4d60b62 457 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 414 440 - T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 ALX04_RS04335 6c0e7d6bf779b6cc7596d392707468a2 626 Gene3D G3DSA:3.90.980.10 111 244 6.8E-41 T 28-03-2018 IPR013264 DNA primase, catalytic core, N-terminal ALX04_RS04335 6c0e7d6bf779b6cc7596d392707468a2 626 SMART SM00400 36 90 1.1E-32 T 28-03-2018 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 ALX04_RS04335 6c0e7d6bf779b6cc7596d392707468a2 626 Gene3D G3DSA:3.40.1360.10 245 370 3.0E-31 T 28-03-2018 ALX04_RS04335 6c0e7d6bf779b6cc7596d392707468a2 626 Gene3D G3DSA:3.90.580.10 1 102 4.2E-35 T 28-03-2018 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 ALX04_RS04335 6c0e7d6bf779b6cc7596d392707468a2 626 SUPERFAMILY SSF57783 4 98 3.74E-35 T 28-03-2018 ALX04_RS04335 6c0e7d6bf779b6cc7596d392707468a2 626 Pfam PF13155 Toprim-like 266 352 1.0E-15 T 28-03-2018 ALX04_RS04335 6c0e7d6bf779b6cc7596d392707468a2 626 SUPERFAMILY SSF56731 118 425 9.16E-95 T 28-03-2018 ALX04_RS04335 6c0e7d6bf779b6cc7596d392707468a2 626 SMART SM00493 263 334 8.1E-11 T 28-03-2018 IPR006171 TOPRIM domain ALX04_RS04335 6c0e7d6bf779b6cc7596d392707468a2 626 TIGRFAM TIGR01391 dnaG: DNA primase 4 421 5.7E-138 T 28-03-2018 IPR006295 DNA primase, DnaG GO:0003896|GO:0006269 ALX04_RS04335 6c0e7d6bf779b6cc7596d392707468a2 626 Pfam PF01807 CHC2 zinc finger 6 99 7.4E-36 T 28-03-2018 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 ALX04_RS04335 6c0e7d6bf779b6cc7596d392707468a2 626 Hamap MF_00974 DNA primase [dnaG]. 4 609 27.552 T 28-03-2018 IPR030846 DNA primase DnaG, bacteria GO:0003896|GO:0006269|GO:0008270 ALX04_RS04335 6c0e7d6bf779b6cc7596d392707468a2 626 Pfam PF08275 DNA primase catalytic core, N-terminal domain 133 255 4.9E-39 T 28-03-2018 IPR013264 DNA primase, catalytic core, N-terminal ALX04_RS04335 6c0e7d6bf779b6cc7596d392707468a2 626 PIRSF PIRSF002811 2 619 3.5E-180 T 28-03-2018 IPR030846 DNA primase DnaG, bacteria GO:0003896|GO:0006269|GO:0008270 ALX04_RS04335 6c0e7d6bf779b6cc7596d392707468a2 626 Pfam PF10410 DnaB-helicase binding domain of primase 374 427 2.3E-7 T 28-03-2018 IPR019475 DNA primase, DnaB-helicase binding domain GO:0016779 ALX04_RS04335 6c0e7d6bf779b6cc7596d392707468a2 626 Gene3D G3DSA:1.10.860.10 482 578 4.3E-7 T 28-03-2018 IPR016136 DNA helicase DnaB, N-terminal/DNA primase DnaG, C-terminal ALX04_RS05365 29c178b0cda3a785d3709d12cda1e27b 558 Hamap MF_01491 Ribonuclease J [rnj]. 6 558 46.218 T 28-03-2018 IPR030854 Ribonuclease J, bacteria GO:0004521|GO:0004534|GO:0006396|GO:0008270|GO:0090501 ALX04_RS05365 29c178b0cda3a785d3709d12cda1e27b 558 PIRSF PIRSF004803 2 558 5.9E-232 T 28-03-2018 IPR030854 Ribonuclease J, bacteria GO:0004521|GO:0004534|GO:0006396|GO:0008270|GO:0090501 ALX04_RS05365 29c178b0cda3a785d3709d12cda1e27b 558 Gene3D G3DSA:3.60.15.10 2 451 1.8E-59 T 28-03-2018 IPR001279 Metallo-beta-lactamase ALX04_RS05365 29c178b0cda3a785d3709d12cda1e27b 558 SUPERFAMILY SSF56281 14 425 4.7E-90 T 28-03-2018 IPR001279 Metallo-beta-lactamase ALX04_RS05365 29c178b0cda3a785d3709d12cda1e27b 558 Pfam PF00753 Metallo-beta-lactamase superfamily 22 169 5.8E-14 T 28-03-2018 IPR001279 Metallo-beta-lactamase ALX04_RS05365 29c178b0cda3a785d3709d12cda1e27b 558 ProSitePatterns PS01292 Uncharacterized protein family UPF0036 signature. 367 395 - T 28-03-2018 IPR001587 Ribonuclease J, conserved site ALX04_RS05365 29c178b0cda3a785d3709d12cda1e27b 558 TIGRFAM TIGR00649 MG423: beta-CASP ribonuclease, RNase J family 12 555 4.8E-204 T 28-03-2018 IPR004613 Ribonuclease J GO:0003723|GO:0046872 ALX04_RS05365 29c178b0cda3a785d3709d12cda1e27b 558 SMART SM00849 23 218 6.3E-22 T 28-03-2018 IPR001279 Metallo-beta-lactamase ALX04_RS05365 29c178b0cda3a785d3709d12cda1e27b 558 Pfam PF07521 Zn-dependent metallo-hydrolase RNA specificity domain 361 411 3.3E-9 T 28-03-2018 IPR011108 Zn-dependent metallo-hydrolase, RNA specificity domain ALX04_RS07760 04c619b3c72efeeeba9dae4f11802112 289 PIRSF PIRSF001365 2 289 1.8E-81 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 ALX04_RS07760 04c619b3c72efeeeba9dae4f11802112 289 SMART SM01130 4 289 9.8E-102 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 ALX04_RS07760 04c619b3c72efeeeba9dae4f11802112 289 ProSitePatterns PS00666 Dihydrodipicolinate synthase signature 2. 137 167 - T 28-03-2018 IPR020625 Schiff base-forming aldolase, active site GO:0008152|GO:0016829 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|Reactome: R-HSA-389661 ALX04_RS07760 04c619b3c72efeeeba9dae4f11802112 289 Hamap MF_00418 4-hydroxy-tetrahydrodipicolinate synthase [dapA]. 4 288 53.141 T 28-03-2018 IPR005263 4-hydroxy-tetrahydrodipicolinate synthase, DapA GO:0008840|GO:0009089 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 ALX04_RS07760 04c619b3c72efeeeba9dae4f11802112 289 TIGRFAM TIGR00674 dapA: 4-hydroxy-tetrahydrodipicolinate synthase 7 287 7.8E-89 T 28-03-2018 IPR005263 4-hydroxy-tetrahydrodipicolinate synthase, DapA GO:0008840|GO:0009089 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 ALX04_RS07760 04c619b3c72efeeeba9dae4f11802112 289 Pfam PF00701 Dihydrodipicolinate synthetase family 6 288 2.6E-86 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 ALX04_RS07760 04c619b3c72efeeeba9dae4f11802112 289 SUPERFAMILY SSF51569 8 289 5.44E-84 T 28-03-2018 ALX04_RS07760 04c619b3c72efeeeba9dae4f11802112 289 PRINTS PR00146 Dihydrodipicolinate synthase signature 107 123 1.1E-29 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 ALX04_RS07760 04c619b3c72efeeeba9dae4f11802112 289 PRINTS PR00146 Dihydrodipicolinate synthase signature 74 92 1.1E-29 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 ALX04_RS07760 04c619b3c72efeeeba9dae4f11802112 289 PRINTS PR00146 Dihydrodipicolinate synthase signature 132 149 1.1E-29 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 ALX04_RS07760 04c619b3c72efeeeba9dae4f11802112 289 PRINTS PR00146 Dihydrodipicolinate synthase signature 38 59 1.1E-29 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 ALX04_RS07760 04c619b3c72efeeeba9dae4f11802112 289 Gene3D G3DSA:3.20.20.70 4 289 7.7E-84 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 ALX04_RS07760 04c619b3c72efeeeba9dae4f11802112 289 ProSitePatterns PS00665 Dihydrodipicolinate synthase signature 1. 41 58 - T 28-03-2018 IPR020624 Schiff base-forming aldolase, conserved site GO:0008152|GO:0016829 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 ALX04_RS08190 e93ca28f00a1a76a2e9089ec6b927607 277 Pfam PF08282 haloacid dehalogenase-like hydrolase 6 264 2.8E-51 T 28-03-2018 IPR023214 HAD-like domain ALX04_RS08190 e93ca28f00a1a76a2e9089ec6b927607 277 ProSitePatterns PS01228 Hypothetical cof family signature 1. 5 16 - T 28-03-2018 ALX04_RS08190 e93ca28f00a1a76a2e9089ec6b927607 277 Gene3D G3DSA:3.40.50.1000 1 273 2.5E-38 T 28-03-2018 IPR023214 HAD-like domain ALX04_RS08190 e93ca28f00a1a76a2e9089ec6b927607 277 SUPERFAMILY SSF56784 1 268 9.32E-57 T 28-03-2018 IPR023214 HAD-like domain ALX04_RS08190 e93ca28f00a1a76a2e9089ec6b927607 277 ProSitePatterns PS01229 Hypothetical cof family signature 2. 218 240 - T 28-03-2018 ALX04_RS08190 e93ca28f00a1a76a2e9089ec6b927607 277 TIGRFAM TIGR00099 Cof-subfamily: Cof-like hydrolase 5 264 4.7E-48 T 28-03-2018 IPR000150 Cof family GO:0016787 ALX04_RS08190 e93ca28f00a1a76a2e9089ec6b927607 277 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 5 237 7.8E-25 T 28-03-2018 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 ALX04_RS01600 86805f416eccf00b4a57b29b96262e75 395 Gene3D G3DSA:3.30.300.10 259 395 3.9E-48 T 28-03-2018 ALX04_RS01600 86805f416eccf00b4a57b29b96262e75 395 ProSitePatterns PS00377 S-adenosylmethionine synthase signature 2. 270 278 - T 28-03-2018 IPR022631 S-adenosylmethionine synthetase, conserved site GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 ALX04_RS01600 86805f416eccf00b4a57b29b96262e75 395 Pfam PF02773 S-adenosylmethionine synthetase, C-terminal domain 244 382 1.3E-68 T 28-03-2018 IPR022630 S-adenosylmethionine synthetase, C-terminal GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 ALX04_RS01600 86805f416eccf00b4a57b29b96262e75 395 TIGRFAM TIGR01034 metK: methionine adenosyltransferase 6 393 3.5E-185 T 28-03-2018 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 ALX04_RS01600 86805f416eccf00b4a57b29b96262e75 395 SUPERFAMILY SSF55973 244 394 4.32E-69 T 28-03-2018 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 ALX04_RS01600 86805f416eccf00b4a57b29b96262e75 395 Hamap MF_00086 S-adenosylmethionine synthase [metK]. 3 394 58.123 T 28-03-2018 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 ALX04_RS01600 86805f416eccf00b4a57b29b96262e75 395 Pfam PF00438 S-adenosylmethionine synthetase, N-terminal domain 5 102 7.6E-43 T 28-03-2018 IPR022628 S-adenosylmethionine synthetase, N-terminal GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 ALX04_RS01600 86805f416eccf00b4a57b29b96262e75 395 Gene3D G3DSA:3.30.300.10 12 142 4.3E-45 T 28-03-2018 ALX04_RS01600 86805f416eccf00b4a57b29b96262e75 395 Gene3D G3DSA:3.30.300.10 143 244 3.0E-47 T 28-03-2018 ALX04_RS01600 86805f416eccf00b4a57b29b96262e75 395 PIRSF PIRSF000497 1 395 1.9E-177 T 28-03-2018 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 ALX04_RS01600 86805f416eccf00b4a57b29b96262e75 395 Pfam PF02772 S-adenosylmethionine synthetase, central domain 124 242 1.4E-48 T 28-03-2018 IPR022629 S-adenosylmethionine synthetase, central domain GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 ALX04_RS01600 86805f416eccf00b4a57b29b96262e75 395 ProSitePatterns PS00376 S-adenosylmethionine synthase signature 1. 126 136 - T 28-03-2018 IPR022631 S-adenosylmethionine synthetase, conserved site GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 ALX04_RS01600 86805f416eccf00b4a57b29b96262e75 395 SUPERFAMILY SSF55973 4 111 1.61E-47 T 28-03-2018 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 ALX04_RS01600 86805f416eccf00b4a57b29b96262e75 395 SUPERFAMILY SSF55973 121 243 1.96E-52 T 28-03-2018 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 ALX04_RS04340 cc607927e00e6556520b70a32b2f4c12 694 SUPERFAMILY SSF109604 335 491 1.62E-18 T 28-03-2018 ALX04_RS04340 cc607927e00e6556520b70a32b2f4c12 694 TIGRFAM TIGR00211 glyS: glycine--tRNA ligase, beta subunit 3 691 3.2E-220 T 28-03-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 ALX04_RS04340 cc607927e00e6556520b70a32b2f4c12 694 Pfam PF02092 Glycyl-tRNA synthetase beta subunit 5 555 9.7E-201 T 28-03-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 ALX04_RS04340 cc607927e00e6556520b70a32b2f4c12 694 PRINTS PR01045 Glycyl-tRNA synthetase beta subunit signature 6 19 1.1E-33 T 28-03-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 ALX04_RS04340 cc607927e00e6556520b70a32b2f4c12 694 PRINTS PR01045 Glycyl-tRNA synthetase beta subunit signature 49 61 1.1E-33 T 28-03-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 ALX04_RS04340 cc607927e00e6556520b70a32b2f4c12 694 PRINTS PR01045 Glycyl-tRNA synthetase beta subunit signature 394 413 1.1E-33 T 28-03-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 ALX04_RS04340 cc607927e00e6556520b70a32b2f4c12 694 PRINTS PR01045 Glycyl-tRNA synthetase beta subunit signature 243 258 1.1E-33 T 28-03-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 ALX04_RS04340 cc607927e00e6556520b70a32b2f4c12 694 PRINTS PR01045 Glycyl-tRNA synthetase beta subunit signature 315 331 1.1E-33 T 28-03-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 ALX04_RS04340 cc607927e00e6556520b70a32b2f4c12 694 Gene3D G3DSA:1.10.3210.10 332 550 6.9E-7 T 28-03-2018 ALX04_RS04340 cc607927e00e6556520b70a32b2f4c12 694 Hamap MF_00255 Glycine--tRNA ligase beta subunit [glyS]. 2 691 27.196 T 28-03-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 ALX04_RS12795 2531c23d2ab2fb28b48e86a9ea4ae577 130 Pfam PF13411 MerR HTH family regulatory protein 2 67 2.0E-13 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 ALX04_RS12795 2531c23d2ab2fb28b48e86a9ea4ae577 130 Gene3D G3DSA:1.10.1660.10 56 129 6.9E-5 T 28-03-2018 ALX04_RS12795 2531c23d2ab2fb28b48e86a9ea4ae577 130 SMART SM00422 2 71 6.4E-9 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 ALX04_RS12795 2531c23d2ab2fb28b48e86a9ea4ae577 130 Gene3D G3DSA:1.10.1660.10 1 55 1.9E-15 T 28-03-2018 ALX04_RS12795 2531c23d2ab2fb28b48e86a9ea4ae577 130 SUPERFAMILY SSF46955 2 113 2.86E-22 T 28-03-2018 IPR009061 Putative DNA-binding domain ALX04_RS03370 6f81ff564c99f27812bd74134acc758d 166 Gene3D G3DSA:3.40.50.620 1 158 7.5E-32 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold ALX04_RS03370 6f81ff564c99f27812bd74134acc758d 166 SUPERFAMILY SSF52402 1 145 6.7E-32 T 28-03-2018 ALX04_RS03370 6f81ff564c99f27812bd74134acc758d 166 PRINTS PR01438 Universal stress protein signature 2 20 2.3E-16 T 28-03-2018 IPR006015 Universal stress protein A ALX04_RS03370 6f81ff564c99f27812bd74134acc758d 166 PRINTS PR01438 Universal stress protein signature 105 117 2.3E-16 T 28-03-2018 IPR006015 Universal stress protein A ALX04_RS03370 6f81ff564c99f27812bd74134acc758d 166 PRINTS PR01438 Universal stress protein signature 123 145 2.3E-16 T 28-03-2018 IPR006015 Universal stress protein A ALX04_RS03370 6f81ff564c99f27812bd74134acc758d 166 Pfam PF00582 Universal stress protein family 1 144 1.9E-30 T 28-03-2018 IPR006016 UspA GO:0006950 ALX04_RS11760 255cc53a547209aefc77dba9c5d9724d 307 Gene3D G3DSA:3.30.420.10 148 307 2.3E-20 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 ALX04_RS11760 255cc53a547209aefc77dba9c5d9724d 307 Gene3D G3DSA:1.10.10.60 3 50 3.7E-11 T 28-03-2018 ALX04_RS11760 255cc53a547209aefc77dba9c5d9724d 307 Pfam PF00665 Integrase core domain 157 261 6.1E-12 T 28-03-2018 IPR001584 Integrase, catalytic core GO:0015074 ALX04_RS11760 255cc53a547209aefc77dba9c5d9724d 307 Pfam PF13936 Helix-turn-helix domain 3 44 8.2E-14 T 28-03-2018 IPR025246 Transposase IS30-like HTH domain ALX04_RS11760 255cc53a547209aefc77dba9c5d9724d 307 Gene3D G3DSA:1.10.10.60 65 99 5.2E-4 T 28-03-2018 ALX04_RS11760 255cc53a547209aefc77dba9c5d9724d 307 Gene3D G3DSA:1.10.10.10 100 133 0.029 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS11760 255cc53a547209aefc77dba9c5d9724d 307 SUPERFAMILY SSF53098 156 301 4.1E-22 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 ALX04_RS13990 255cc53a547209aefc77dba9c5d9724d 307 Gene3D G3DSA:3.30.420.10 148 307 2.3E-20 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 ALX04_RS13990 255cc53a547209aefc77dba9c5d9724d 307 Gene3D G3DSA:1.10.10.60 3 50 3.7E-11 T 28-03-2018 ALX04_RS13990 255cc53a547209aefc77dba9c5d9724d 307 Pfam PF00665 Integrase core domain 157 261 6.1E-12 T 28-03-2018 IPR001584 Integrase, catalytic core GO:0015074 ALX04_RS13990 255cc53a547209aefc77dba9c5d9724d 307 Pfam PF13936 Helix-turn-helix domain 3 44 8.2E-14 T 28-03-2018 IPR025246 Transposase IS30-like HTH domain ALX04_RS13990 255cc53a547209aefc77dba9c5d9724d 307 Gene3D G3DSA:1.10.10.60 65 99 5.2E-4 T 28-03-2018 ALX04_RS13990 255cc53a547209aefc77dba9c5d9724d 307 Gene3D G3DSA:1.10.10.10 100 133 0.029 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS13990 255cc53a547209aefc77dba9c5d9724d 307 SUPERFAMILY SSF53098 156 301 4.1E-22 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 ALX04_RS00715 255cc53a547209aefc77dba9c5d9724d 307 Gene3D G3DSA:3.30.420.10 148 307 2.3E-20 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 ALX04_RS00715 255cc53a547209aefc77dba9c5d9724d 307 Gene3D G3DSA:1.10.10.60 3 50 3.7E-11 T 28-03-2018 ALX04_RS00715 255cc53a547209aefc77dba9c5d9724d 307 Pfam PF00665 Integrase core domain 157 261 6.1E-12 T 28-03-2018 IPR001584 Integrase, catalytic core GO:0015074 ALX04_RS00715 255cc53a547209aefc77dba9c5d9724d 307 Pfam PF13936 Helix-turn-helix domain 3 44 8.2E-14 T 28-03-2018 IPR025246 Transposase IS30-like HTH domain ALX04_RS00715 255cc53a547209aefc77dba9c5d9724d 307 Gene3D G3DSA:1.10.10.60 65 99 5.2E-4 T 28-03-2018 ALX04_RS00715 255cc53a547209aefc77dba9c5d9724d 307 Gene3D G3DSA:1.10.10.10 100 133 0.029 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS00715 255cc53a547209aefc77dba9c5d9724d 307 SUPERFAMILY SSF53098 156 301 4.1E-22 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 ALX04_RS08575 255cc53a547209aefc77dba9c5d9724d 307 Gene3D G3DSA:3.30.420.10 148 307 2.3E-20 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 ALX04_RS08575 255cc53a547209aefc77dba9c5d9724d 307 Gene3D G3DSA:1.10.10.60 3 50 3.7E-11 T 28-03-2018 ALX04_RS08575 255cc53a547209aefc77dba9c5d9724d 307 Pfam PF00665 Integrase core domain 157 261 6.1E-12 T 28-03-2018 IPR001584 Integrase, catalytic core GO:0015074 ALX04_RS08575 255cc53a547209aefc77dba9c5d9724d 307 Pfam PF13936 Helix-turn-helix domain 3 44 8.2E-14 T 28-03-2018 IPR025246 Transposase IS30-like HTH domain ALX04_RS08575 255cc53a547209aefc77dba9c5d9724d 307 Gene3D G3DSA:1.10.10.60 65 99 5.2E-4 T 28-03-2018 ALX04_RS08575 255cc53a547209aefc77dba9c5d9724d 307 Gene3D G3DSA:1.10.10.10 100 133 0.029 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS08575 255cc53a547209aefc77dba9c5d9724d 307 SUPERFAMILY SSF53098 156 301 4.1E-22 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 ALX04_RS10230 255cc53a547209aefc77dba9c5d9724d 307 Gene3D G3DSA:3.30.420.10 148 307 2.3E-20 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 ALX04_RS10230 255cc53a547209aefc77dba9c5d9724d 307 Gene3D G3DSA:1.10.10.60 3 50 3.7E-11 T 28-03-2018 ALX04_RS10230 255cc53a547209aefc77dba9c5d9724d 307 Pfam PF00665 Integrase core domain 157 261 6.1E-12 T 28-03-2018 IPR001584 Integrase, catalytic core GO:0015074 ALX04_RS10230 255cc53a547209aefc77dba9c5d9724d 307 Pfam PF13936 Helix-turn-helix domain 3 44 8.2E-14 T 28-03-2018 IPR025246 Transposase IS30-like HTH domain ALX04_RS10230 255cc53a547209aefc77dba9c5d9724d 307 Gene3D G3DSA:1.10.10.60 65 99 5.2E-4 T 28-03-2018 ALX04_RS10230 255cc53a547209aefc77dba9c5d9724d 307 Gene3D G3DSA:1.10.10.10 100 133 0.029 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS10230 255cc53a547209aefc77dba9c5d9724d 307 SUPERFAMILY SSF53098 156 301 4.1E-22 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 ALX04_RS12565 0a7c930293e3cac1ad8ece2850a500ae 691 Gene3D G3DSA:3.40.930.10 524 690 1.6E-11 T 28-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 ALX04_RS12565 0a7c930293e3cac1ad8ece2850a500ae 691 Pfam PF05043 Mga helix-turn-helix domain 98 165 2.7E-5 T 28-03-2018 IPR007737 Mga helix-turn-helix domain ALX04_RS12565 0a7c930293e3cac1ad8ece2850a500ae 691 Gene3D G3DSA:1.10.10.10 1 65 1.1E-7 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS12565 0a7c930293e3cac1ad8ece2850a500ae 691 Gene3D G3DSA:1.10.10.10 88 156 5.8E-9 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS12565 0a7c930293e3cac1ad8ece2850a500ae 691 SUPERFAMILY SSF52794 419 503 3.3E-6 T 28-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 ALX04_RS12565 0a7c930293e3cac1ad8ece2850a500ae 691 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 553 683 1.5E-9 T 28-03-2018 IPR002178 PTS EIIA type-2 domain ALX04_RS12565 0a7c930293e3cac1ad8ece2850a500ae 691 Gene3D G3DSA:3.40.50.2300 417 506 6.7E-14 T 28-03-2018 ALX04_RS12565 0a7c930293e3cac1ad8ece2850a500ae 691 SUPERFAMILY SSF63520 311 410 6.28E-15 T 28-03-2018 IPR011608 PRD domain GO:0006355 ALX04_RS12565 0a7c930293e3cac1ad8ece2850a500ae 691 SUPERFAMILY SSF55804 550 683 1.44E-15 T 28-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 ALX04_RS12565 0a7c930293e3cac1ad8ece2850a500ae 691 Pfam PF00874 PRD domain 321 409 1.1E-10 T 28-03-2018 IPR011608 PRD domain GO:0006355 ALX04_RS12565 0a7c930293e3cac1ad8ece2850a500ae 691 Gene3D G3DSA:1.10.1790.10 300 414 1.3E-11 T 28-03-2018 IPR011608 PRD domain GO:0006355 ALX04_RS08580 9c4bbf212bc189170ea4237f31b89ccf 154 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 2 61 6.8E-22 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 ALX04_RS08580 9c4bbf212bc189170ea4237f31b89ccf 154 SUPERFAMILY SSF53850 91 145 3.2E-7 T 28-03-2018 ALX04_RS08580 9c4bbf212bc189170ea4237f31b89ccf 154 Gene3D G3DSA:3.40.190.10 83 151 3.7E-8 T 28-03-2018 ALX04_RS08580 9c4bbf212bc189170ea4237f31b89ccf 154 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 17 28 2.3E-8 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 ALX04_RS08580 9c4bbf212bc189170ea4237f31b89ccf 154 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 38 49 2.3E-8 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 ALX04_RS08580 9c4bbf212bc189170ea4237f31b89ccf 154 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 28 38 2.3E-8 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 ALX04_RS08580 9c4bbf212bc189170ea4237f31b89ccf 154 Gene3D G3DSA:1.10.10.10 1 81 1.6E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS08580 9c4bbf212bc189170ea4237f31b89ccf 154 Pfam PF03466 LysR substrate binding domain 91 146 4.5E-7 T 28-03-2018 IPR005119 LysR, substrate-binding ALX04_RS08580 9c4bbf212bc189170ea4237f31b89ccf 154 SUPERFAMILY SSF46785 3 80 7.99E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS07660 0681eeb91e5899e813d1fba18b6b8601 241 Pfam PF00392 Bacterial regulatory proteins, gntR family 6 67 5.0E-14 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 ALX04_RS07660 0681eeb91e5899e813d1fba18b6b8601 241 Pfam PF07702 UTRA domain 94 229 1.8E-28 T 28-03-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 ALX04_RS07660 0681eeb91e5899e813d1fba18b6b8601 241 SMART SM00866 93 232 3.5E-31 T 28-03-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 ALX04_RS07660 0681eeb91e5899e813d1fba18b6b8601 241 SUPERFAMILY SSF64288 55 237 1.57E-39 T 28-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain ALX04_RS07660 0681eeb91e5899e813d1fba18b6b8601 241 Gene3D G3DSA:1.10.10.10 3 69 7.0E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS07660 0681eeb91e5899e813d1fba18b6b8601 241 Gene3D G3DSA:3.40.1410.10 82 241 2.1E-31 T 28-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain ALX04_RS07660 0681eeb91e5899e813d1fba18b6b8601 241 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 27 41 6.4E-9 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 ALX04_RS07660 0681eeb91e5899e813d1fba18b6b8601 241 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 41 57 6.4E-9 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 ALX04_RS07660 0681eeb91e5899e813d1fba18b6b8601 241 SUPERFAMILY SSF46785 5 71 1.57E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS07660 0681eeb91e5899e813d1fba18b6b8601 241 SMART SM00345 9 67 8.7E-9 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 ALX04_RS07910 62e538ee55c584bf6595610389a6ff6c 739 Pfam PF02769 AIR synthase related protein, C-terminal domain 208 361 1.9E-30 T 28-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain ALX04_RS07910 62e538ee55c584bf6595610389a6ff6c 739 Pfam PF02769 AIR synthase related protein, C-terminal domain 578 712 3.6E-12 T 28-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain ALX04_RS07910 62e538ee55c584bf6595610389a6ff6c 739 SUPERFAMILY SSF55326 406 570 1.22E-48 T 28-03-2018 IPR016188 PurM-like, N-terminal domain ALX04_RS07910 62e538ee55c584bf6595610389a6ff6c 739 SUPERFAMILY SSF56042 207 431 7.33E-52 T 28-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain ALX04_RS07910 62e538ee55c584bf6595610389a6ff6c 739 Gene3D G3DSA:3.90.650.10 571 739 5.9E-32 T 28-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain ALX04_RS07910 62e538ee55c584bf6595610389a6ff6c 739 Gene3D G3DSA:3.90.650.10 204 381 2.2E-28 T 28-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain ALX04_RS07910 62e538ee55c584bf6595610389a6ff6c 739 Gene3D G3DSA:3.30.1330.10 421 569 9.6E-45 T 28-03-2018 IPR016188 PurM-like, N-terminal domain ALX04_RS07910 62e538ee55c584bf6595610389a6ff6c 739 Gene3D G3DSA:3.30.1330.10 24 203 2.8E-53 T 28-03-2018 IPR016188 PurM-like, N-terminal domain ALX04_RS07910 62e538ee55c584bf6595610389a6ff6c 739 Pfam PF00586 AIR synthase related protein, N-terminal domain 93 194 9.6E-25 T 28-03-2018 IPR016188 PurM-like, N-terminal domain ALX04_RS07910 62e538ee55c584bf6595610389a6ff6c 739 Pfam PF00586 AIR synthase related protein, N-terminal domain 457 564 1.6E-21 T 28-03-2018 IPR016188 PurM-like, N-terminal domain ALX04_RS07910 62e538ee55c584bf6595610389a6ff6c 739 Hamap MF_00420 Phosphoribosylformylglycinamidine synthase subunit PurL [purL]. 1 739 294.008 T 28-03-2018 IPR010074 Phosphoribosylformylglycinamidine subunit PurL GO:0004642|GO:0005737|GO:0006189 KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 ALX04_RS07910 62e538ee55c584bf6595610389a6ff6c 739 SUPERFAMILY SSF56042 574 738 2.54E-36 T 28-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain ALX04_RS07910 62e538ee55c584bf6595610389a6ff6c 739 SUPERFAMILY SSF55326 42 201 1.01E-48 T 28-03-2018 IPR016188 PurM-like, N-terminal domain ALX04_RS07910 62e538ee55c584bf6595610389a6ff6c 739 TIGRFAM TIGR01736 FGAM_synth_II: phosphoribosylformylglycinamidine synthase II 23 737 2.6E-273 T 28-03-2018 IPR010074 Phosphoribosylformylglycinamidine subunit PurL GO:0004642|GO:0005737|GO:0006189 KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 ALX04_RS07910 62e538ee55c584bf6595610389a6ff6c 739 PIRSF PIRSF001587 8 739 2.9E-286 T 28-03-2018 IPR010074 Phosphoribosylformylglycinamidine subunit PurL GO:0004642|GO:0005737|GO:0006189 KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 ALX04_RS07910 62e538ee55c584bf6595610389a6ff6c 739 SUPERFAMILY SSF109736 7 59 9.81E-11 T 28-03-2018 ALX04_RS08140 080451fbaa341eace570dfcf25c719c0 247 Pfam PF00005 ABC transporter 21 162 1.6E-28 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 ALX04_RS08140 080451fbaa341eace570dfcf25c719c0 247 Gene3D G3DSA:3.40.50.300 2 247 3.3E-61 T 28-03-2018 ALX04_RS08140 080451fbaa341eace570dfcf25c719c0 247 SUPERFAMILY SSF52540 7 224 2.46E-58 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase ALX04_RS08140 080451fbaa341eace570dfcf25c719c0 247 ProSitePatterns PS00211 ABC transporters family signature. 135 149 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 ALX04_RS08140 080451fbaa341eace570dfcf25c719c0 247 SMART SM00382 30 209 1.4E-8 T 28-03-2018 IPR003593 AAA+ ATPase domain ALX04_RS15025 4898347f2b028dd8fcdcc1ba792f5419 579 SUPERFAMILY SSF52518 3 172 3.53E-43 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold ALX04_RS15025 4898347f2b028dd8fcdcc1ba792f5419 579 Gene3D G3DSA:3.40.50.1220 192 342 3.6E-29 T 28-03-2018 IPR029035 DHS-like NAD/FAD-binding domain ALX04_RS15025 4898347f2b028dd8fcdcc1ba792f5419 579 ProSitePatterns PS00187 Thiamine pyrophosphate enzymes signature. 419 438 - T 28-03-2018 IPR000399 TPP-binding enzyme, conserved site GO:0000287|GO:0030976 ALX04_RS15025 4898347f2b028dd8fcdcc1ba792f5419 579 TIGRFAM TIGR02720 pyruv_oxi_spxB: pyruvate oxidase 6 575 3.5E-300 T 28-03-2018 IPR014092 Pyruvate oxidase GO:0047112|GO:0055114 KEGG: 00620+1.2.3.3 ALX04_RS15025 4898347f2b028dd8fcdcc1ba792f5419 579 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 193 321 9.8E-29 T 28-03-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 ALX04_RS15025 4898347f2b028dd8fcdcc1ba792f5419 579 Gene3D G3DSA:3.40.50.970 343 546 5.5E-33 T 28-03-2018 ALX04_RS15025 4898347f2b028dd8fcdcc1ba792f5419 579 SUPERFAMILY SSF52467 185 351 8.59E-39 T 28-03-2018 IPR029035 DHS-like NAD/FAD-binding domain ALX04_RS15025 4898347f2b028dd8fcdcc1ba792f5419 579 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 5 172 1.8E-42 T 28-03-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 ALX04_RS15025 4898347f2b028dd8fcdcc1ba792f5419 579 SUPERFAMILY SSF52518 356 576 4.95E-52 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold ALX04_RS15025 4898347f2b028dd8fcdcc1ba792f5419 579 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 382 529 1.1E-35 T 28-03-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 ALX04_RS15025 4898347f2b028dd8fcdcc1ba792f5419 579 Gene3D G3DSA:3.40.50.970 1 191 4.6E-39 T 28-03-2018 ALX04_RS15485 6d60d958adfd58cac096ec027d464fe5 220 Gene3D G3DSA:3.40.250.10 116 220 6.0E-24 T 28-03-2018 IPR001763 Rhodanese-like domain ALX04_RS15485 6d60d958adfd58cac096ec027d464fe5 220 Pfam PF01022 Bacterial regulatory protein, arsR family 26 70 9.8E-13 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 ALX04_RS15485 6d60d958adfd58cac096ec027d464fe5 220 SMART SM00418 18 96 3.6E-20 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 ALX04_RS15485 6d60d958adfd58cac096ec027d464fe5 220 Gene3D G3DSA:1.10.10.10 2 98 8.3E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS15485 6d60d958adfd58cac096ec027d464fe5 220 Pfam PF00581 Rhodanese-like domain 124 211 1.3E-14 T 28-03-2018 IPR001763 Rhodanese-like domain ALX04_RS15485 6d60d958adfd58cac096ec027d464fe5 220 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 20 35 6.9E-7 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 ALX04_RS15485 6d60d958adfd58cac096ec027d464fe5 220 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 52 67 6.9E-7 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 ALX04_RS15485 6d60d958adfd58cac096ec027d464fe5 220 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 67 82 6.9E-7 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 ALX04_RS15485 6d60d958adfd58cac096ec027d464fe5 220 SMART SM00450 119 215 6.4E-18 T 28-03-2018 IPR001763 Rhodanese-like domain ALX04_RS15485 6d60d958adfd58cac096ec027d464fe5 220 SUPERFAMILY SSF52821 113 212 1.13E-24 T 28-03-2018 IPR001763 Rhodanese-like domain ALX04_RS15485 6d60d958adfd58cac096ec027d464fe5 220 SUPERFAMILY SSF46785 12 97 2.25E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS04575 6a18b59d7a1fb83a417065f2ba5c5556 484 Pfam PF07690 Major Facilitator Superfamily 11 347 9.2E-22 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 ALX04_RS04575 6a18b59d7a1fb83a417065f2ba5c5556 484 SMART SM00830 393 472 1.6E-22 T 28-03-2018 IPR002701 Chorismate mutase GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 ALX04_RS04575 6a18b59d7a1fb83a417065f2ba5c5556 484 Gene3D G3DSA:1.20.59.10 401 478 2.6E-21 T 28-03-2018 IPR002701 Chorismate mutase GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 ALX04_RS04575 6a18b59d7a1fb83a417065f2ba5c5556 484 Gene3D G3DSA:1.20.1250.20 2 177 2.0E-18 T 28-03-2018 ALX04_RS04575 6a18b59d7a1fb83a417065f2ba5c5556 484 Pfam PF01817 Chorismate mutase type II 393 469 8.3E-20 T 28-03-2018 IPR020822 Chorismate mutase, type II GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 ALX04_RS04575 6a18b59d7a1fb83a417065f2ba5c5556 484 SUPERFAMILY SSF103473 6 386 4.19E-35 T 28-03-2018 IPR020846 Major facilitator superfamily domain ALX04_RS04575 6a18b59d7a1fb83a417065f2ba5c5556 484 ProSitePatterns PS00216 Sugar transport proteins signature 1. 60 76 - T 28-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 ALX04_RS04575 6a18b59d7a1fb83a417065f2ba5c5556 484 Gene3D G3DSA:1.20.1250.20 183 400 1.1E-14 T 28-03-2018 ALX04_RS04575 6a18b59d7a1fb83a417065f2ba5c5556 484 SUPERFAMILY SSF48600 388 474 8.24E-20 T 28-03-2018 IPR020822 Chorismate mutase, type II GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 ALX04_RS04520 80e891378142a2347f3782790efb552b 622 TIGRFAM TIGR02350 prok_dnaK: chaperone protein DnaK 5 577 2.7E-278 T 28-03-2018 IPR012725 Chaperone DnaK GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-1268020|Reactome: R-HSA-3371453|Reactome: R-HSA-8949613 ALX04_RS04520 80e891378142a2347f3782790efb552b 622 SUPERFAMILY SSF100934 480 577 7.06E-11 T 28-03-2018 IPR029048 Heat shock protein 70kD, C-terminal domain ALX04_RS04520 80e891378142a2347f3782790efb552b 622 Gene3D G3DSA:3.30.420.40 3 173 4.4E-64 T 28-03-2018 ALX04_RS04520 80e891378142a2347f3782790efb552b 622 PRINTS PR00301 70kDa heat shock protein signature 5 18 2.5E-75 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 ALX04_RS04520 80e891378142a2347f3782790efb552b 622 PRINTS PR00301 70kDa heat shock protein signature 33 45 2.5E-75 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 ALX04_RS04520 80e891378142a2347f3782790efb552b 622 PRINTS PR00301 70kDa heat shock protein signature 442 458 2.5E-75 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 ALX04_RS04520 80e891378142a2347f3782790efb552b 622 PRINTS PR00301 70kDa heat shock protein signature 175 185 2.5E-75 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 ALX04_RS04520 80e891378142a2347f3782790efb552b 622 PRINTS PR00301 70kDa heat shock protein signature 55 63 2.5E-75 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 ALX04_RS04520 80e891378142a2347f3782790efb552b 622 PRINTS PR00301 70kDa heat shock protein signature 338 358 2.5E-75 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 ALX04_RS04520 80e891378142a2347f3782790efb552b 622 PRINTS PR00301 70kDa heat shock protein signature 361 380 2.5E-75 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 ALX04_RS04520 80e891378142a2347f3782790efb552b 622 PRINTS PR00301 70kDa heat shock protein signature 115 135 2.5E-75 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 ALX04_RS04520 80e891378142a2347f3782790efb552b 622 PRINTS PR00301 70kDa heat shock protein signature 307 323 2.5E-75 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 ALX04_RS04520 80e891378142a2347f3782790efb552b 622 ProSitePatterns PS00297 Heat shock hsp70 proteins family signature 1. 9 16 - T 28-03-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 ALX04_RS04520 80e891378142a2347f3782790efb552b 622 Gene3D G3DSA:3.30.420.40 174 334 7.9E-46 T 28-03-2018 ALX04_RS04520 80e891378142a2347f3782790efb552b 622 SUPERFAMILY SSF53067 163 354 7.13E-65 T 28-03-2018 ALX04_RS04520 80e891378142a2347f3782790efb552b 622 Pfam PF00012 Hsp70 protein 75 577 1.6E-217 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 ALX04_RS04520 80e891378142a2347f3782790efb552b 622 ProSitePatterns PS00329 Heat shock hsp70 proteins family signature 2. 169 182 - T 28-03-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 ALX04_RS04520 80e891378142a2347f3782790efb552b 622 SUPERFAMILY SSF53067 5 160 4.44E-54 T 28-03-2018 ALX04_RS04520 80e891378142a2347f3782790efb552b 622 Gene3D G3DSA:1.20.1270.10 506 591 6.4E-20 T 28-03-2018 IPR029048 Heat shock protein 70kD, C-terminal domain ALX04_RS04520 80e891378142a2347f3782790efb552b 622 Hamap MF_00332 Chaperone protein DnaK [dnaK]. 3 615 35.834 T 28-03-2018 IPR012725 Chaperone DnaK GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-1268020|Reactome: R-HSA-3371453|Reactome: R-HSA-8949613 ALX04_RS04520 80e891378142a2347f3782790efb552b 622 SUPERFAMILY SSF100920 357 513 2.88E-61 T 28-03-2018 IPR029047 Heat shock protein 70kD, peptide-binding domain Reactome: R-HSA-3371453 ALX04_RS04520 80e891378142a2347f3782790efb552b 622 ProSitePatterns PS01036 Heat shock hsp70 proteins family signature 3. 310 324 - T 28-03-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 ALX04_RS04520 80e891378142a2347f3782790efb552b 622 Gene3D G3DSA:2.60.34.10 363 505 2.9E-65 T 28-03-2018 IPR029047 Heat shock protein 70kD, peptide-binding domain Reactome: R-HSA-3371453 ALX04_RS08535 3ab3eb842ad285042837a8fa5c4d472a 207 Pfam PF00717 Peptidase S24-like 34 107 2.1E-12 T 28-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C ALX04_RS08535 3ab3eb842ad285042837a8fa5c4d472a 207 ProSitePatterns PS00761 Signal peptidases I signature 3. 162 175 - T 28-03-2018 IPR019758 Peptidase S26A, signal peptidase I, conserved site GO:0008236|GO:0016021 ALX04_RS08535 3ab3eb842ad285042837a8fa5c4d472a 207 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 82 94 1.6E-16 T 28-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 ALX04_RS08535 3ab3eb842ad285042837a8fa5c4d472a 207 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 28 44 1.6E-16 T 28-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 ALX04_RS08535 3ab3eb842ad285042837a8fa5c4d472a 207 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 157 176 1.6E-16 T 28-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 ALX04_RS08535 3ab3eb842ad285042837a8fa5c4d472a 207 TIGRFAM TIGR02227 sigpep_I_bact: signal peptidase I 11 195 5.4E-40 T 28-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 ALX04_RS08535 3ab3eb842ad285042837a8fa5c4d472a 207 ProSitePatterns PS00760 Signal peptidases I lysine active site. 84 96 - T 28-03-2018 IPR019757 Peptidase S26A, signal peptidase I, lysine active site GO:0008236|GO:0016021 ALX04_RS08535 3ab3eb842ad285042837a8fa5c4d472a 207 Gene3D G3DSA:2.10.109.10 24 206 1.2E-34 T 28-03-2018 ALX04_RS08535 3ab3eb842ad285042837a8fa5c4d472a 207 SUPERFAMILY SSF51306 26 196 6.02E-45 T 28-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C ALX04_RS02930 3674737245aabf9ab637e958a10ccdff 254 ProSitePatterns PS00211 ABC transporters family signature. 133 147 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 ALX04_RS02930 3674737245aabf9ab637e958a10ccdff 254 SUPERFAMILY SSF52540 1 223 2.95E-58 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase ALX04_RS02930 3674737245aabf9ab637e958a10ccdff 254 Pfam PF00005 ABC transporter 17 160 3.6E-27 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 ALX04_RS02930 3674737245aabf9ab637e958a10ccdff 254 SMART SM00382 26 208 1.1E-8 T 28-03-2018 IPR003593 AAA+ ATPase domain ALX04_RS02930 3674737245aabf9ab637e958a10ccdff 254 Gene3D G3DSA:3.40.50.300 1 242 1.4E-59 T 28-03-2018 ALX04_RS13195 10fed8685bc18a979c7669f35d1f24c2 505 TIGRFAM TIGR01311 glycerol_kin: glycerol kinase 4 493 4.6E-220 T 28-03-2018 IPR005999 Glycerol kinase GO:0004370|GO:0006072 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261|Reactome: R-HSA-75109 ALX04_RS13195 10fed8685bc18a979c7669f35d1f24c2 505 SUPERFAMILY SSF53067 255 493 4.37E-79 T 28-03-2018 ALX04_RS13195 10fed8685bc18a979c7669f35d1f24c2 505 Gene3D G3DSA:3.30.420.40 1 249 3.7E-87 T 28-03-2018 ALX04_RS13195 10fed8685bc18a979c7669f35d1f24c2 505 PIRSF PIRSF000538 3 499 1.0E-164 T 28-03-2018 IPR000577 Carbohydrate kinase, FGGY GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 ALX04_RS13195 10fed8685bc18a979c7669f35d1f24c2 505 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 262 450 6.5E-55 T 28-03-2018 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 ALX04_RS13195 10fed8685bc18a979c7669f35d1f24c2 505 Hamap MF_00186 Glycerol kinase [glpK]. 3 497 56.713 T 28-03-2018 IPR005999 Glycerol kinase GO:0004370|GO:0006072 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261|Reactome: R-HSA-75109 ALX04_RS13195 10fed8685bc18a979c7669f35d1f24c2 505 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 5 252 1.9E-86 T 28-03-2018 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 ALX04_RS13195 10fed8685bc18a979c7669f35d1f24c2 505 ProSitePatterns PS00933 FGGY family of carbohydrate kinases signature 1. 135 147 - T 28-03-2018 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 ALX04_RS13195 10fed8685bc18a979c7669f35d1f24c2 505 SUPERFAMILY SSF53067 4 254 5.11E-96 T 28-03-2018 ALX04_RS13195 10fed8685bc18a979c7669f35d1f24c2 505 Gene3D G3DSA:3.30.420.40 250 499 6.9E-73 T 28-03-2018 ALX04_RS13195 10fed8685bc18a979c7669f35d1f24c2 505 ProSitePatterns PS00445 FGGY family of carbohydrate kinases signature 2. 362 382 - T 28-03-2018 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 ALX04_RS03760 c568d327856757a1819c77d6a8201d2a 208 Hamap MF_01043 Glycerol-3-phosphate acyltransferase [plsY]. 5 194 19.302 T 28-03-2018 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 ALX04_RS03760 c568d327856757a1819c77d6a8201d2a 208 TIGRFAM TIGR00023 TIGR00023: acyl-phosphate glycerol 3-phosphate acyltransferase 3 193 7.0E-53 T 28-03-2018 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 ALX04_RS03760 c568d327856757a1819c77d6a8201d2a 208 Pfam PF02660 Glycerol-3-phosphate acyltransferase 9 185 9.1E-49 T 28-03-2018 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 ALX04_RS03760 c568d327856757a1819c77d6a8201d2a 208 SMART SM01207 8 186 6.2E-79 T 28-03-2018 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 ALX04_RS08650 aaa688f15e5b1aa6b52aad18dfa13151 84 SUPERFAMILY SSF46955 1 58 2.98E-6 T 28-03-2018 IPR009061 Putative DNA-binding domain ALX04_RS08650 aaa688f15e5b1aa6b52aad18dfa13151 84 Gene3D G3DSA:1.10.1660.10 1 83 3.4E-4 T 28-03-2018 ALX04_RS02795 54f2cabfbd6c1d5b6e5dd10147984507 805 SUPERFAMILY SSF52540 292 434 1.24E-40 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase ALX04_RS02795 54f2cabfbd6c1d5b6e5dd10147984507 805 SUPERFAMILY SSF52540 461 515 1.24E-40 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase ALX04_RS02795 54f2cabfbd6c1d5b6e5dd10147984507 805 SUPERFAMILY SSF52540 578 675 1.24E-40 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase ALX04_RS02795 54f2cabfbd6c1d5b6e5dd10147984507 805 Gene3D G3DSA:3.90.820.10 516 564 1.9E-5 T 28-03-2018 ALX04_RS02795 54f2cabfbd6c1d5b6e5dd10147984507 805 SMART SM00490 567 664 2.1E-10 T 28-03-2018 IPR001650 Helicase, C-terminal ALX04_RS02795 54f2cabfbd6c1d5b6e5dd10147984507 805 Gene3D G3DSA:3.40.50.300 565 689 1.2E-16 T 28-03-2018 ALX04_RS02795 54f2cabfbd6c1d5b6e5dd10147984507 805 Gene3D G3DSA:3.40.50.300 248 446 2.0E-28 T 28-03-2018 ALX04_RS02795 54f2cabfbd6c1d5b6e5dd10147984507 805 TIGRFAM TIGR00595 priA: primosomal protein N' 293 802 4.3E-209 T 28-03-2018 IPR005259 Primosomal protein N' GO:0003677|GO:0004003|GO:0006260|GO:0032508 ALX04_RS02795 54f2cabfbd6c1d5b6e5dd10147984507 805 Pfam PF04851 Type III restriction enzyme, res subunit 267 432 2.1E-16 T 28-03-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 ALX04_RS02795 54f2cabfbd6c1d5b6e5dd10147984507 805 SMART SM00487 265 464 2.1E-24 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain ALX04_RS02795 54f2cabfbd6c1d5b6e5dd10147984507 805 Hamap MF_00983 Probable primosomal protein N' [priA]. 10 804 25.337 T 28-03-2018 IPR005259 Primosomal protein N' GO:0003677|GO:0004003|GO:0006260|GO:0032508 ALX04_RS02795 54f2cabfbd6c1d5b6e5dd10147984507 805 Pfam PF00271 Helicase conserved C-terminal domain 579 663 1.2E-8 T 28-03-2018 IPR001650 Helicase, C-terminal ALX04_RS12930 466a794b41a6be21c7ce9ad2f7fb027d 398 SUPERFAMILY SSF53067 1 196 1.75E-61 T 28-03-2018 ALX04_RS12930 466a794b41a6be21c7ce9ad2f7fb027d 398 ProSitePatterns PS01076 Acetate and butyrate kinases family signature 2. 203 220 - T 28-03-2018 IPR023865 Aliphatic acid kinase, short-chain, conserved site GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 ALX04_RS12930 466a794b41a6be21c7ce9ad2f7fb027d 398 Gene3D G3DSA:3.30.420.40 3 195 6.1E-65 T 28-03-2018 ALX04_RS12930 466a794b41a6be21c7ce9ad2f7fb027d 398 ProSitePatterns PS01075 Acetate and butyrate kinases family signature 1. 4 15 - T 28-03-2018 IPR023865 Aliphatic acid kinase, short-chain, conserved site GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 ALX04_RS12930 466a794b41a6be21c7ce9ad2f7fb027d 398 SUPERFAMILY SSF53067 157 394 5.0E-86 T 28-03-2018 ALX04_RS12930 466a794b41a6be21c7ce9ad2f7fb027d 398 Pfam PF00871 Acetokinase family 3 389 6.4E-141 T 28-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 ALX04_RS12930 466a794b41a6be21c7ce9ad2f7fb027d 398 Gene3D G3DSA:3.30.420.40 196 398 3.2E-75 T 28-03-2018 ALX04_RS12930 466a794b41a6be21c7ce9ad2f7fb027d 398 PIRSF PIRSF000722 1 398 5.8E-141 T 28-03-2018 IPR004372 Acetate/propionate kinase GO:0006082|GO:0016301|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 ALX04_RS12930 466a794b41a6be21c7ce9ad2f7fb027d 398 PRINTS PR00471 Acetate kinase family signature 203 224 7.5E-42 T 28-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 ALX04_RS12930 466a794b41a6be21c7ce9ad2f7fb027d 398 PRINTS PR00471 Acetate kinase family signature 376 388 7.5E-42 T 28-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 ALX04_RS12930 466a794b41a6be21c7ce9ad2f7fb027d 398 PRINTS PR00471 Acetate kinase family signature 4 15 7.5E-42 T 28-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 ALX04_RS12930 466a794b41a6be21c7ce9ad2f7fb027d 398 PRINTS PR00471 Acetate kinase family signature 173 186 7.5E-42 T 28-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 ALX04_RS12930 466a794b41a6be21c7ce9ad2f7fb027d 398 PRINTS PR00471 Acetate kinase family signature 322 338 7.5E-42 T 28-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 ALX04_RS12930 466a794b41a6be21c7ce9ad2f7fb027d 398 PRINTS PR00471 Acetate kinase family signature 300 313 7.5E-42 T 28-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 ALX04_RS12930 466a794b41a6be21c7ce9ad2f7fb027d 398 Hamap MF_00020 Acetate kinase [ackA]. 1 398 171.336 T 28-03-2018 IPR004372 Acetate/propionate kinase GO:0006082|GO:0016301|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 ALX04_RS12930 466a794b41a6be21c7ce9ad2f7fb027d 398 TIGRFAM TIGR00016 ackA: acetate kinase 2 395 2.2E-144 T 28-03-2018 IPR004372 Acetate/propionate kinase GO:0006082|GO:0016301|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 ALX04_RS02825 fb4ebcc5cca12780c9a73d7a3fe6aeec 217 SUPERFAMILY SSF51366 1 213 1.88E-68 T 28-03-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 ALX04_RS02825 fb4ebcc5cca12780c9a73d7a3fe6aeec 217 TIGRFAM TIGR01163 rpe: ribulose-phosphate 3-epimerase 3 213 6.1E-84 T 28-03-2018 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 ALX04_RS02825 fb4ebcc5cca12780c9a73d7a3fe6aeec 217 ProSitePatterns PS01085 Ribulose-phosphate 3-epimerase family signature 1. 31 45 - T 28-03-2018 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 ALX04_RS02825 fb4ebcc5cca12780c9a73d7a3fe6aeec 217 ProSitePatterns PS01086 Ribulose-phosphate 3-epimerase family signature 2. 133 155 - T 28-03-2018 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 ALX04_RS02825 fb4ebcc5cca12780c9a73d7a3fe6aeec 217 Gene3D G3DSA:3.20.20.70 1 216 2.0E-77 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 ALX04_RS02825 fb4ebcc5cca12780c9a73d7a3fe6aeec 217 Pfam PF00834 Ribulose-phosphate 3 epimerase family 3 200 1.5E-75 T 28-03-2018 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 ALX04_RS02825 fb4ebcc5cca12780c9a73d7a3fe6aeec 217 PIRSF PIRSF001461 1 217 5.5E-86 T 28-03-2018 IPR026019 Ribulose-phosphate 3-epimerase GO:0004750|GO:0006098 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 ALX04_RS10740 b688869f267a65374d5fced7f4847ac7 222 Gene3D G3DSA:1.10.260.40 35 161 4.1E-8 T 28-03-2018 ALX04_RS10740 b688869f267a65374d5fced7f4847ac7 222 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 13 26 2.9E-5 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 ALX04_RS10740 b688869f267a65374d5fced7f4847ac7 222 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 34 57 2.9E-5 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 ALX04_RS10740 b688869f267a65374d5fced7f4847ac7 222 Pfam PF00440 Bacterial regulatory proteins, tetR family 13 55 2.4E-11 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 ALX04_RS10740 b688869f267a65374d5fced7f4847ac7 222 SUPERFAMILY SSF46689 3 63 5.34E-13 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 ALX04_RS10740 b688869f267a65374d5fced7f4847ac7 222 Gene3D G3DSA:1.10.10.60 1 34 1.9E-13 T 28-03-2018 ALX04_RS14860 1018b7427dd5e675fcd5616a26c935fd 300 SUPERFAMILY SSF51735 2 142 1.91E-37 T 28-03-2018 IPR016040 NAD(P)-binding domain ALX04_RS14860 1018b7427dd5e675fcd5616a26c935fd 300 Gene3D G3DSA:3.30.360.10 130 297 7.3E-16 T 28-03-2018 ALX04_RS14860 1018b7427dd5e675fcd5616a26c935fd 300 Gene3D G3DSA:3.40.50.720 1 129 5.1E-29 T 28-03-2018 ALX04_RS14860 1018b7427dd5e675fcd5616a26c935fd 300 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 2 120 1.3E-19 T 28-03-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 ALX04_RS14860 1018b7427dd5e675fcd5616a26c935fd 300 SUPERFAMILY SSF55347 126 262 8.17E-36 T 28-03-2018 ALX04_RS00055 a7182f9ae8dbc0a4cf4c42e516668081 335 TIGRFAM TIGR00669 asnA: aspartate--ammonia ligase 18 326 3.2E-107 T 28-03-2018 IPR004618 Aspartate--ammonia ligase GO:0004071|GO:0005737|GO:0006529 KEGG: 00250+6.3.1.1|KEGG: 00460+6.3.1.1 ALX04_RS00055 a7182f9ae8dbc0a4cf4c42e516668081 335 PIRSF PIRSF001555 7 335 1.4E-167 T 28-03-2018 IPR004618 Aspartate--ammonia ligase GO:0004071|GO:0005737|GO:0006529 KEGG: 00250+6.3.1.1|KEGG: 00460+6.3.1.1 ALX04_RS00055 a7182f9ae8dbc0a4cf4c42e516668081 335 Pfam PF03590 Aspartate-ammonia ligase 19 245 3.6E-109 T 28-03-2018 IPR004618 Aspartate--ammonia ligase GO:0004071|GO:0005737|GO:0006529 KEGG: 00250+6.3.1.1|KEGG: 00460+6.3.1.1 ALX04_RS00055 a7182f9ae8dbc0a4cf4c42e516668081 335 Hamap MF_00555 Aspartate--ammonia ligase [asnA]. 11 331 52.523 T 28-03-2018 IPR004618 Aspartate--ammonia ligase GO:0004071|GO:0005737|GO:0006529 KEGG: 00250+6.3.1.1|KEGG: 00460+6.3.1.1 ALX04_RS00055 a7182f9ae8dbc0a4cf4c42e516668081 335 Gene3D G3DSA:3.30.930.10 7 330 9.6E-44 T 28-03-2018 ALX04_RS00055 a7182f9ae8dbc0a4cf4c42e516668081 335 SUPERFAMILY SSF55681 15 327 3.83E-101 T 28-03-2018 ALX04_RS15145 e34becd4a5dc0b450913aa6b2d5e9125 278 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 45 267 5.8E-56 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF ALX04_RS15145 e34becd4a5dc0b450913aa6b2d5e9125 278 Gene3D G3DSA:3.40.190.10 35 147 3.1E-29 T 28-03-2018 ALX04_RS15145 e34becd4a5dc0b450913aa6b2d5e9125 278 SMART SM00079 53 267 9.1E-4 T 28-03-2018 IPR001320 Ionotropic glutamate receptor GO:0004970|GO:0016020 ALX04_RS15145 e34becd4a5dc0b450913aa6b2d5e9125 278 SUPERFAMILY SSF53850 8 267 4.45E-67 T 28-03-2018 ALX04_RS15145 e34becd4a5dc0b450913aa6b2d5e9125 278 Gene3D G3DSA:3.40.190.10 148 233 1.4E-18 T 28-03-2018 ALX04_RS15145 e34becd4a5dc0b450913aa6b2d5e9125 278 SMART SM00062 44 268 2.4E-71 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF ALX04_RS09860 b3e1f1f977c664a30cfad95896f91510 229 SMART SM00448 1 112 4.6E-43 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 ALX04_RS09860 b3e1f1f977c664a30cfad95896f91510 229 Pfam PF00072 Response regulator receiver domain 3 112 1.3E-26 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 ALX04_RS09860 b3e1f1f977c664a30cfad95896f91510 229 Gene3D G3DSA:1.10.10.10 122 229 8.8E-29 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS09860 b3e1f1f977c664a30cfad95896f91510 229 SMART SM00862 150 226 6.0E-23 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 ALX04_RS09860 b3e1f1f977c664a30cfad95896f91510 229 SUPERFAMILY SSF46894 126 227 1.64E-26 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 ALX04_RS09860 b3e1f1f977c664a30cfad95896f91510 229 Gene3D G3DSA:3.40.50.2300 1 121 1.5E-35 T 28-03-2018 ALX04_RS09860 b3e1f1f977c664a30cfad95896f91510 229 SUPERFAMILY SSF52172 1 121 6.55E-38 T 28-03-2018 IPR011006 CheY-like superfamily ALX04_RS09860 b3e1f1f977c664a30cfad95896f91510 229 Pfam PF00486 Transcriptional regulatory protein, C terminal 150 226 5.9E-24 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 ALX04_RS14210 750942ee65c4b98dbf2909a3394b0d8a 227 SUPERFAMILY SSF100950 1 148 4.57E-45 T 28-03-2018 ALX04_RS14210 750942ee65c4b98dbf2909a3394b0d8a 227 SUPERFAMILY SSF75445 129 206 5.62E-22 T 28-03-2018 ALX04_RS14210 750942ee65c4b98dbf2909a3394b0d8a 227 Gene3D G3DSA:3.40.50.1360 1 140 1.2E-39 T 28-03-2018 ALX04_RS14210 750942ee65c4b98dbf2909a3394b0d8a 227 Gene3D G3DSA:3.30.70.260 141 203 9.6E-24 T 28-03-2018 ALX04_RS14210 750942ee65c4b98dbf2909a3394b0d8a 227 Pfam PF06026 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) 52 219 3.5E-59 T 28-03-2018 IPR004788 Ribose 5-phosphate isomerase, type A GO:0004751|GO:0009052 KEGG: 00030+5.3.1.6|KEGG: 00051+5.3.1.6|KEGG: 00710+5.3.1.6|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 ALX04_RS14210 750942ee65c4b98dbf2909a3394b0d8a 227 TIGRFAM TIGR00021 rpiA: ribose 5-phosphate isomerase A 7 219 7.5E-85 T 28-03-2018 IPR004788 Ribose 5-phosphate isomerase, type A GO:0004751|GO:0009052 KEGG: 00030+5.3.1.6|KEGG: 00051+5.3.1.6|KEGG: 00710+5.3.1.6|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 ALX04_RS14210 750942ee65c4b98dbf2909a3394b0d8a 227 Hamap MF_00170 Ribose-5-phosphate isomerase A [rpiA]. 3 223 31.858 T 28-03-2018 IPR020672 Ribose-5-phosphate isomerase, type A, subgroup GO:0004751|GO:0009052 KEGG: 00030+5.3.1.6|KEGG: 00051+5.3.1.6|KEGG: 00710+5.3.1.6|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 ALX04_RS07835 27b9d38780d16fc065f754a9dc473f41 311 Hamap MF_00001 Aspartate carbamoyltransferase [pyrB]. 4 300 38.21 T 28-03-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 ALX04_RS07835 27b9d38780d16fc065f754a9dc473f41 311 Gene3D G3DSA:3.40.50.1370 157 310 3.6E-40 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 ALX04_RS07835 27b9d38780d16fc065f754a9dc473f41 311 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 251 260 6.3E-22 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 ALX04_RS07835 27b9d38780d16fc065f754a9dc473f41 311 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 46 65 6.3E-22 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 ALX04_RS07835 27b9d38780d16fc065f754a9dc473f41 311 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 263 286 6.3E-22 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 ALX04_RS07835 27b9d38780d16fc065f754a9dc473f41 311 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 131 142 6.3E-22 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 ALX04_RS07835 27b9d38780d16fc065f754a9dc473f41 311 PRINTS PR00101 Aspartate carbamoyltransferase signature 74 83 2.5E-31 T 28-03-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 ALX04_RS07835 27b9d38780d16fc065f754a9dc473f41 311 PRINTS PR00101 Aspartate carbamoyltransferase signature 255 260 2.5E-31 T 28-03-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 ALX04_RS07835 27b9d38780d16fc065f754a9dc473f41 311 PRINTS PR00101 Aspartate carbamoyltransferase signature 212 221 2.5E-31 T 28-03-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 ALX04_RS07835 27b9d38780d16fc065f754a9dc473f41 311 PRINTS PR00101 Aspartate carbamoyltransferase signature 36 58 2.5E-31 T 28-03-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 ALX04_RS07835 27b9d38780d16fc065f754a9dc473f41 311 PRINTS PR00101 Aspartate carbamoyltransferase signature 130 147 2.5E-31 T 28-03-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 ALX04_RS07835 27b9d38780d16fc065f754a9dc473f41 311 PRINTS PR00101 Aspartate carbamoyltransferase signature 279 293 2.5E-31 T 28-03-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 ALX04_RS07835 27b9d38780d16fc065f754a9dc473f41 311 ProSitePatterns PS00097 Aspartate and ornithine carbamoyltransferases signature. 46 53 - T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 ALX04_RS07835 27b9d38780d16fc065f754a9dc473f41 311 Pfam PF02729 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain 6 144 3.1E-33 T 28-03-2018 IPR006132 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding GO:0006520|GO:0016743 ALX04_RS07835 27b9d38780d16fc065f754a9dc473f41 311 Gene3D G3DSA:3.40.50.1370 2 156 1.6E-49 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 ALX04_RS07835 27b9d38780d16fc065f754a9dc473f41 311 Pfam PF00185 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain 150 296 2.6E-22 T 28-03-2018 IPR006131 Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain GO:0006520|GO:0016597|GO:0016743 ALX04_RS07835 27b9d38780d16fc065f754a9dc473f41 311 TIGRFAM TIGR00670 asp_carb_tr: aspartate carbamoyltransferase 6 298 4.5E-86 T 28-03-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 ALX04_RS07835 27b9d38780d16fc065f754a9dc473f41 311 SUPERFAMILY SSF53671 4 299 4.84E-87 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 ALX04_RS01170 d2e435f244e1215bd4b2797143d7a360 302 Gene3D G3DSA:3.90.550.10 2 284 5.7E-31 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases ALX04_RS01170 d2e435f244e1215bd4b2797143d7a360 302 Pfam PF13641 Glycosyltransferase like family 2 4 237 3.1E-21 T 28-03-2018 ALX04_RS01170 d2e435f244e1215bd4b2797143d7a360 302 SUPERFAMILY SSF53448 1 267 3.86E-39 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases ALX04_RS04540 3623c33f328f73ab28f70bd15a852a8c 333 SMART SM00904 186 311 1.1E-51 T 28-03-2018 IPR015865 Riboflavin kinase domain, bacterial/eukaryotic GO:0008531|GO:0009231 Reactome: R-HSA-196843 ALX04_RS04540 3623c33f328f73ab28f70bd15a852a8c 333 SUPERFAMILY SSF82114 177 310 3.27E-40 T 28-03-2018 IPR015865 Riboflavin kinase domain, bacterial/eukaryotic GO:0008531|GO:0009231 Reactome: R-HSA-196843 ALX04_RS04540 3623c33f328f73ab28f70bd15a852a8c 333 TIGRFAM TIGR00083 ribF: riboflavin biosynthesis protein RibF 21 309 6.1E-74 T 28-03-2018 IPR002606 Riboflavin kinase, bacterial GO:0003919|GO:0008531|GO:0009231 KEGG: 00740+2.7.1.26+2.7.7.2|MetaCyc: PWY-5523|MetaCyc: PWY-6167|MetaCyc: PWY-6168|MetaCyc: PWY-7863 ALX04_RS04540 3623c33f328f73ab28f70bd15a852a8c 333 Pfam PF06574 FAD synthetase 19 170 5.2E-45 T 28-03-2018 IPR015864 FAD synthetase GO:0003919|GO:0009231 KEGG: 00740+2.7.1.26+2.7.7.2|MetaCyc: PWY-5523|MetaCyc: PWY-6167|MetaCyc: PWY-6168|MetaCyc: PWY-7863 ALX04_RS04540 3623c33f328f73ab28f70bd15a852a8c 333 SUPERFAMILY SSF52374 19 179 1.6E-28 T 28-03-2018 ALX04_RS04540 3623c33f328f73ab28f70bd15a852a8c 333 Gene3D G3DSA:3.40.50.620 7 182 2.6E-41 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold ALX04_RS04540 3623c33f328f73ab28f70bd15a852a8c 333 Gene3D G3DSA:2.40.30.30 183 330 1.1E-33 T 28-03-2018 IPR023465 Riboflavin kinase domain GO:0008531|GO:0009231 Reactome: R-HSA-196843 ALX04_RS04540 3623c33f328f73ab28f70bd15a852a8c 333 Pfam PF01687 Riboflavin kinase 187 309 2.3E-30 T 28-03-2018 IPR015865 Riboflavin kinase domain, bacterial/eukaryotic GO:0008531|GO:0009231 Reactome: R-HSA-196843 ALX04_RS04540 3623c33f328f73ab28f70bd15a852a8c 333 PIRSF PIRSF004491 5 314 1.4E-91 T 28-03-2018 IPR002606 Riboflavin kinase, bacterial GO:0003919|GO:0008531|GO:0009231 KEGG: 00740+2.7.1.26+2.7.7.2|MetaCyc: PWY-5523|MetaCyc: PWY-6167|MetaCyc: PWY-6168|MetaCyc: PWY-7863 ALX04_RS14405 5c35a05a9fb24b22613f9380756b9147 298 Gene3D G3DSA:3.30.950.10 124 237 1.9E-38 T 28-03-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 ALX04_RS14405 5c35a05a9fb24b22613f9380756b9147 298 SUPERFAMILY SSF53790 13 232 3.93E-83 T 28-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 ALX04_RS14405 5c35a05a9fb24b22613f9380756b9147 298 ProSitePatterns PS01296 RsmI AdoMet-dependent methyltransferase protein family signature. 93 104 - T 28-03-2018 IPR018063 SAM-dependent methyltransferase RsmI, conserved site GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 ALX04_RS14405 5c35a05a9fb24b22613f9380756b9147 298 PIRSF PIRSF005917 3 294 2.8E-101 T 28-03-2018 IPR008189 rRNA small subunit methyltransferase I GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 ALX04_RS14405 5c35a05a9fb24b22613f9380756b9147 298 Gene3D G3DSA:3.40.1010.10 13 123 2.5E-43 T 28-03-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 ALX04_RS14405 5c35a05a9fb24b22613f9380756b9147 298 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 15 215 9.1E-29 T 28-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 ALX04_RS14405 5c35a05a9fb24b22613f9380756b9147 298 Hamap MF_01877 Ribosomal RNA small subunit methyltransferase I [rsmI]. 15 234 36.14 T 28-03-2018 IPR008189 rRNA small subunit methyltransferase I GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 ALX04_RS14405 5c35a05a9fb24b22613f9380756b9147 298 TIGRFAM TIGR00096 TIGR00096: 16S rRNA (cytidine(1402)-2'-O)-methyltransferase 16 290 5.1E-87 T 28-03-2018 IPR008189 rRNA small subunit methyltransferase I GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 ALX04_RS06295 df9deb9c79c20ac7a89ec4515adea6d3 751 SUPERFAMILY SSF56059 485 596 8.0E-11 T 28-03-2018 ALX04_RS06295 df9deb9c79c20ac7a89ec4515adea6d3 751 SUPERFAMILY SSF56059 656 698 8.0E-11 T 28-03-2018 ALX04_RS06295 df9deb9c79c20ac7a89ec4515adea6d3 751 Gene3D G3DSA:3.40.50.20 419 499 0.34 T 28-03-2018 ALX04_RS06295 df9deb9c79c20ac7a89ec4515adea6d3 751 SUPERFAMILY SSF55931 3 447 9.16E-95 T 28-03-2018 ALX04_RS06295 df9deb9c79c20ac7a89ec4515adea6d3 751 Pfam PF04262 Glutamate-cysteine ligase 232 322 5.6E-7 T 28-03-2018 IPR007370 Glutamate--cysteine ligase GO:0004357|GO:0006750 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 ALX04_RS06295 df9deb9c79c20ac7a89ec4515adea6d3 751 Pfam PF04262 Glutamate-cysteine ligase 17 208 1.7E-35 T 28-03-2018 IPR007370 Glutamate--cysteine ligase GO:0004357|GO:0006750 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 ALX04_RS06295 df9deb9c79c20ac7a89ec4515adea6d3 751 Gene3D G3DSA:3.30.470.20 561 702 1.9E-8 T 28-03-2018 ALX04_RS06295 df9deb9c79c20ac7a89ec4515adea6d3 751 Gene3D G3DSA:3.30.1490.20 500 560 9.6E-6 T 28-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 ALX04_RS03390 3aab5de77e90e2bc6502dc1c1cabe2a8 767 Gene3D G3DSA:3.40.710.10 281 760 3.3E-78 T 28-03-2018 ALX04_RS03390 3aab5de77e90e2bc6502dc1c1cabe2a8 767 SUPERFAMILY SSF56601 236 258 2.82E-91 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like ALX04_RS03390 3aab5de77e90e2bc6502dc1c1cabe2a8 767 SUPERFAMILY SSF56601 296 658 2.82E-91 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like ALX04_RS03390 3aab5de77e90e2bc6502dc1c1cabe2a8 767 Pfam PF00905 Penicillin binding protein transpeptidase domain 355 637 2.7E-32 T 28-03-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 ALX04_RS03390 3aab5de77e90e2bc6502dc1c1cabe2a8 767 Gene3D G3DSA:1.10.3810.10 68 271 9.8E-70 T 28-03-2018 IPR001264 Glycosyl transferase, family 51 ALX04_RS03390 3aab5de77e90e2bc6502dc1c1cabe2a8 767 Pfam PF00912 Transglycosylase 79 254 9.5E-61 T 28-03-2018 IPR001264 Glycosyl transferase, family 51 ALX04_RS03390 3aab5de77e90e2bc6502dc1c1cabe2a8 767 SUPERFAMILY SSF53955 67 275 1.07E-66 T 28-03-2018 IPR023346 Lysozyme-like domain ALX04_RS04370 48ab1ed33ca69a26bac4db985c1328e0 325 Pfam PF02562 PhoH-like protein 117 320 3.0E-92 T 28-03-2018 IPR003714 PhoH-like protein GO:0005524 ALX04_RS04370 48ab1ed33ca69a26bac4db985c1328e0 325 Gene3D G3DSA:3.40.50.300 116 320 3.4E-27 T 28-03-2018 ALX04_RS04370 48ab1ed33ca69a26bac4db985c1328e0 325 SUPERFAMILY SSF52540 113 283 1.25E-36 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase ALX04_RS08560 d067c6417236ec91ece9bcb7c5cb4286 212 SMART SM00855 5 177 1.6E-11 T 28-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 ALX04_RS08560 d067c6417236ec91ece9bcb7c5cb4286 212 Gene3D G3DSA:3.40.50.1240 1 212 1.3E-27 T 28-03-2018 IPR029033 Histidine phosphatase superfamily ALX04_RS08560 d067c6417236ec91ece9bcb7c5cb4286 212 SUPERFAMILY SSF53254 1 207 3.14E-32 T 28-03-2018 IPR029033 Histidine phosphatase superfamily ALX04_RS08560 d067c6417236ec91ece9bcb7c5cb4286 212 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 7 207 1.5E-22 T 28-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 ALX04_RS07605 7c37c8e8176ced38ff3ac97cebe48e04 785 Gene3D G3DSA:1.10.530.10 241 389 3.3E-37 T 28-03-2018 ALX04_RS07605 7c37c8e8176ced38ff3ac97cebe48e04 785 SMART SM00287 722 784 0.024 T 28-03-2018 IPR003646 SH3-like domain, bacterial-type ALX04_RS07605 7c37c8e8176ced38ff3ac97cebe48e04 785 SMART SM00287 569 635 0.32 T 28-03-2018 IPR003646 SH3-like domain, bacterial-type ALX04_RS07605 7c37c8e8176ced38ff3ac97cebe48e04 785 SMART SM00287 493 559 0.23 T 28-03-2018 IPR003646 SH3-like domain, bacterial-type ALX04_RS07605 7c37c8e8176ced38ff3ac97cebe48e04 785 SMART SM00287 416 482 0.83 T 28-03-2018 IPR003646 SH3-like domain, bacterial-type ALX04_RS07605 7c37c8e8176ced38ff3ac97cebe48e04 785 SMART SM00287 646 710 2.1 T 28-03-2018 IPR003646 SH3-like domain, bacterial-type ALX04_RS07605 7c37c8e8176ced38ff3ac97cebe48e04 785 Gene3D G3DSA:2.30.30.410 393 481 5.1E-9 T 28-03-2018 ALX04_RS07605 7c37c8e8176ced38ff3ac97cebe48e04 785 Gene3D G3DSA:2.30.30.410 629 706 5.8E-8 T 28-03-2018 ALX04_RS07605 7c37c8e8176ced38ff3ac97cebe48e04 785 Gene3D G3DSA:2.30.30.410 482 554 1.3E-11 T 28-03-2018 ALX04_RS07605 7c37c8e8176ced38ff3ac97cebe48e04 785 Gene3D G3DSA:2.30.30.410 707 783 2.2E-12 T 28-03-2018 ALX04_RS07605 7c37c8e8176ced38ff3ac97cebe48e04 785 Gene3D G3DSA:2.30.30.410 556 628 3.9E-8 T 28-03-2018 ALX04_RS07605 7c37c8e8176ced38ff3ac97cebe48e04 785 Pfam PF08460 Bacterial SH3 domain 492 551 6.1E-10 T 28-03-2018 IPR003646 SH3-like domain, bacterial-type ALX04_RS07605 7c37c8e8176ced38ff3ac97cebe48e04 785 Pfam PF08460 Bacterial SH3 domain 414 475 8.3E-11 T 28-03-2018 IPR003646 SH3-like domain, bacterial-type ALX04_RS07605 7c37c8e8176ced38ff3ac97cebe48e04 785 Pfam PF08460 Bacterial SH3 domain 567 628 1.1E-11 T 28-03-2018 IPR003646 SH3-like domain, bacterial-type ALX04_RS07605 7c37c8e8176ced38ff3ac97cebe48e04 785 Pfam PF08460 Bacterial SH3 domain 644 705 2.7E-12 T 28-03-2018 IPR003646 SH3-like domain, bacterial-type ALX04_RS07605 7c37c8e8176ced38ff3ac97cebe48e04 785 Pfam PF08460 Bacterial SH3 domain 721 780 2.5E-11 T 28-03-2018 IPR003646 SH3-like domain, bacterial-type ALX04_RS07605 7c37c8e8176ced38ff3ac97cebe48e04 785 SMART SM00047 237 389 2.6E-34 T 28-03-2018 IPR002901 Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like domain GO:0004040 ALX04_RS07605 7c37c8e8176ced38ff3ac97cebe48e04 785 Pfam PF01832 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase 258 384 9.1E-24 T 28-03-2018 IPR002901 Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like domain GO:0004040 ALX04_RS11025 c69e7a2acd70a5ad64d0f591069f26b9 319 Gene3D G3DSA:2.70.98.10 1 319 9.6E-73 T 28-03-2018 IPR014718 Glycoside hydrolase-type carbohydrate-binding GO:0030246 ALX04_RS11025 c69e7a2acd70a5ad64d0f591069f26b9 319 Pfam PF02929 Beta galactosidase small chain 20 317 3.3E-59 T 28-03-2018 IPR004199 Beta galactosidase small chain/ domain 5 GO:0004565|GO:0005975|GO:0009341 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 ALX04_RS11025 c69e7a2acd70a5ad64d0f591069f26b9 319 SUPERFAMILY SSF74650 3 318 3.61E-75 T 28-03-2018 IPR011013 Galactose mutarotase-like domain GO:0003824|GO:0005975|GO:0030246 ALX04_RS11025 c69e7a2acd70a5ad64d0f591069f26b9 319 SMART SM01038 18 318 1.7E-103 T 28-03-2018 IPR004199 Beta galactosidase small chain/ domain 5 GO:0004565|GO:0005975|GO:0009341 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 ALX04_RS12735 5804dddedeb6d998c13b8671f057f950 939 SUPERFAMILY SSF53756 167 408 2.89E-13 T 28-03-2018 ALX04_RS12735 5804dddedeb6d998c13b8671f057f950 939 Pfam PF04464 CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase 39 407 4.0E-76 T 28-03-2018 IPR007554 CDP-glycerol glycerophosphotransferase GO:0016020|GO:0047355 ALX04_RS12735 5804dddedeb6d998c13b8671f057f950 939 Gene3D G3DSA:3.40.50.2000 676 825 4.6E-29 T 28-03-2018 ALX04_RS12735 5804dddedeb6d998c13b8671f057f950 939 SUPERFAMILY SSF53756 519 816 1.2E-42 T 28-03-2018 ALX04_RS12735 5804dddedeb6d998c13b8671f057f950 939 SUPERFAMILY SSF53756 424 492 1.2E-42 T 28-03-2018 ALX04_RS12735 5804dddedeb6d998c13b8671f057f950 939 Pfam PF00534 Glycosyl transferases group 1 673 816 3.4E-23 T 28-03-2018 IPR001296 Glycosyl transferase, family 1 ALX04_RS05150 967bac4e96ba2613402194e1185aab7c 264 Gene3D G3DSA:3.20.20.140 12 244 2.1E-23 T 28-03-2018 ALX04_RS05150 967bac4e96ba2613402194e1185aab7c 264 PIRSF PIRSF016557 13 264 8.6E-99 T 28-03-2018 IPR016667 Capsular polysaccharide synthesis, CpsB/CapC GO:0004725|GO:0030145 ALX04_RS05150 967bac4e96ba2613402194e1185aab7c 264 SUPERFAMILY SSF89550 13 216 5.49E-18 T 28-03-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 ALX04_RS05335 3831943cb3ed2f67fcd09667d6788d18 438 Gene3D G3DSA:2.40.50.100 47 121 3.8E-7 T 28-03-2018 ALX04_RS05335 3831943cb3ed2f67fcd09667d6788d18 438 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 27 56 - T 28-03-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 ALX04_RS05335 3831943cb3ed2f67fcd09667d6788d18 438 Pfam PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) 207 436 5.8E-85 T 28-03-2018 IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 ALX04_RS05335 3831943cb3ed2f67fcd09667d6788d18 438 Gene3D G3DSA:3.90.1170.30 2 46 4.9E-12 T 28-03-2018 ALX04_RS05335 3831943cb3ed2f67fcd09667d6788d18 438 Pfam PF02817 e3 binding domain 128 162 7.6E-11 T 28-03-2018 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 ALX04_RS05335 3831943cb3ed2f67fcd09667d6788d18 438 Pfam PF00364 Biotin-requiring enzyme 4 76 2.2E-22 T 28-03-2018 IPR000089 Biotin/lipoyl attachment ALX04_RS05335 3831943cb3ed2f67fcd09667d6788d18 438 Gene3D G3DSA:4.10.320.10 122 192 3.6E-15 T 28-03-2018 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 ALX04_RS05335 3831943cb3ed2f67fcd09667d6788d18 438 Gene3D G3DSA:3.30.559.10 193 436 3.8E-87 T 28-03-2018 ALX04_RS05335 3831943cb3ed2f67fcd09667d6788d18 438 SUPERFAMILY SSF51230 1 95 4.84E-27 T 28-03-2018 IPR011053 Single hybrid motif ALX04_RS05335 3831943cb3ed2f67fcd09667d6788d18 438 SUPERFAMILY SSF52777 203 436 1.29E-85 T 28-03-2018 ALX04_RS05335 3831943cb3ed2f67fcd09667d6788d18 438 SUPERFAMILY SSF47005 122 166 2.62E-11 T 28-03-2018 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 ALX04_RS14055 39e2cd87b09ec040faddc25076cc3af3 378 Gene3D G3DSA:2.30.40.10 1 67 1.1E-9 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 ALX04_RS14055 39e2cd87b09ec040faddc25076cc3af3 378 TIGRFAM TIGR00221 nagA: N-acetylglucosamine-6-phosphate deacetylase 3 370 1.9E-92 T 28-03-2018 IPR003764 N-acetylglucosamine-6-phosphate deacetylase GO:0006044|GO:0008448 KEGG: 00052+3.5.1.25|KEGG: 00520+3.5.1.25|MetaCyc: PWY-6906|MetaCyc: PWY-7077|MetaCyc: PWY-7395|Reactome: R-HSA-446210 ALX04_RS14055 39e2cd87b09ec040faddc25076cc3af3 378 SUPERFAMILY SSF51556 56 345 6.35E-92 T 28-03-2018 IPR032466 Metal-dependent hydrolase ALX04_RS14055 39e2cd87b09ec040faddc25076cc3af3 378 PIRSF PIRSF038994 1 378 1.6E-113 T 28-03-2018 IPR003764 N-acetylglucosamine-6-phosphate deacetylase GO:0006044|GO:0008448 KEGG: 00052+3.5.1.25|KEGG: 00520+3.5.1.25|MetaCyc: PWY-6906|MetaCyc: PWY-7077|MetaCyc: PWY-7395|Reactome: R-HSA-446210 ALX04_RS14055 39e2cd87b09ec040faddc25076cc3af3 378 SUPERFAMILY SSF51338 1 55 5.32E-11 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 ALX04_RS14055 39e2cd87b09ec040faddc25076cc3af3 378 SUPERFAMILY SSF51338 347 375 5.32E-11 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 ALX04_RS14055 39e2cd87b09ec040faddc25076cc3af3 378 Gene3D G3DSA:3.20.20.140 68 347 3.7E-93 T 28-03-2018 ALX04_RS14055 39e2cd87b09ec040faddc25076cc3af3 378 Pfam PF01979 Amidohydrolase family 52 372 2.3E-22 T 28-03-2018 IPR006680 Amidohydrolase-related GO:0016787 ALX04_RS13625 6d0b3eaf0a049cd5f95ac91411d926c1 537 SUPERFAMILY SSF52540 1 270 2.7E-126 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase ALX04_RS13625 6d0b3eaf0a049cd5f95ac91411d926c1 537 Gene3D G3DSA:3.40.50.880 287 536 2.7E-74 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like ALX04_RS13625 6d0b3eaf0a049cd5f95ac91411d926c1 537 TIGRFAM TIGR00337 PyrG: CTP synthase 1 528 1.6E-253 T 28-03-2018 IPR004468 CTP synthase GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 ALX04_RS13625 6d0b3eaf0a049cd5f95ac91411d926c1 537 SUPERFAMILY SSF52317 290 530 1.09E-76 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like ALX04_RS13625 6d0b3eaf0a049cd5f95ac91411d926c1 537 Gene3D G3DSA:3.40.50.300 1 286 6.1E-133 T 28-03-2018 ALX04_RS13625 6d0b3eaf0a049cd5f95ac91411d926c1 537 Pfam PF06418 CTP synthase N-terminus 3 266 2.4E-129 T 28-03-2018 IPR017456 CTP synthase, N-terminal GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 ALX04_RS13625 6d0b3eaf0a049cd5f95ac91411d926c1 537 Pfam PF00117 Glutamine amidotransferase class-I 302 527 4.5E-56 T 28-03-2018 IPR017926 Glutamine amidotransferase ALX04_RS13625 6d0b3eaf0a049cd5f95ac91411d926c1 537 Hamap MF_01227 CTP synthase [pyrG]. 2 533 51.467 T 28-03-2018 IPR004468 CTP synthase GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 ALX04_RS12425 a009a5b5765ead56658bec39d1b6bb3c 553 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 87 473 4.0E-73 T 28-03-2018 IPR000914 Solute-binding protein family 5 domain ALX04_RS12425 a009a5b5765ead56658bec39d1b6bb3c 553 PIRSF PIRSF002741 2 553 5.7E-94 T 28-03-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 ALX04_RS12425 a009a5b5765ead56658bec39d1b6bb3c 553 Gene3D G3DSA:3.10.105.10 309 523 2.3E-42 T 28-03-2018 ALX04_RS12425 a009a5b5765ead56658bec39d1b6bb3c 553 SUPERFAMILY SSF53850 44 550 3.34E-118 T 28-03-2018 ALX04_RS12425 a009a5b5765ead56658bec39d1b6bb3c 553 Gene3D G3DSA:3.90.76.10 54 213 3.2E-39 T 28-03-2018 ALX04_RS12425 a009a5b5765ead56658bec39d1b6bb3c 553 Gene3D G3DSA:3.40.190.10 214 308 9.3E-21 T 28-03-2018 ALX04_RS12425 a009a5b5765ead56658bec39d1b6bb3c 553 ProSitePatterns PS01040 Bacterial extracellular solute-binding proteins, family 5 signature. 93 115 - T 28-03-2018 IPR023765 Solute-binding protein family 5, conserved site ALX04_RS11470 19ab50d0bcf00ccc973ca299b50c3320 867 Gene3D G3DSA:3.40.50.1970 436 647 7.9E-53 T 28-03-2018 ALX04_RS11470 19ab50d0bcf00ccc973ca299b50c3320 867 Pfam PF00465 Iron-containing alcohol dehydrogenase 463 849 9.9E-112 T 28-03-2018 IPR001670 Alcohol dehydrogenase, iron-type GO:0016491|GO:0046872|GO:0055114 Reactome: R-HSA-880009 ALX04_RS11470 19ab50d0bcf00ccc973ca299b50c3320 867 Gene3D G3DSA:3.40.605.10 7 234 1.3E-30 T 28-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 ALX04_RS11470 19ab50d0bcf00ccc973ca299b50c3320 867 SUPERFAMILY SSF53720 14 459 6.94E-83 T 28-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 ALX04_RS11470 19ab50d0bcf00ccc973ca299b50c3320 867 Pfam PF00171 Aldehyde dehydrogenase family 13 274 6.5E-24 T 28-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 ALX04_RS11470 19ab50d0bcf00ccc973ca299b50c3320 867 ProSitePatterns PS00913 Iron-containing alcohol dehydrogenases signature 1. 636 664 - T 28-03-2018 IPR018211 Alcohol dehydrogenase, iron-type, conserved site GO:0016491|GO:0046872|GO:0055114 ALX04_RS11470 19ab50d0bcf00ccc973ca299b50c3320 867 SUPERFAMILY SSF56796 454 863 3.27E-114 T 28-03-2018 ALX04_RS11470 19ab50d0bcf00ccc973ca299b50c3320 867 PIRSF PIRSF000111 1 864 0.0 T 28-03-2018 IPR012079 Bifunctional aldehyde-alcohol dehydrogenase GO:0004022|GO:0006066|GO:0008774|GO:0015976|GO:0055114 KEGG: 00010+1.1.1.1|KEGG: 00071+1.1.1.1|KEGG: 00260+1.1.1.1|KEGG: 00350+1.1.1.1|KEGG: 00592+1.1.1.1|KEGG: 00625+1.1.1.1|KEGG: 00626+1.1.1.1|KEGG: 00830+1.1.1.1|KEGG: 00980+1.1.1.1|KEGG: 00982+1.1.1.1|MetaCyc: PWY-3162|MetaCyc: PWY-5057|MetaCyc: PWY-5076|MetaCyc: PWY-5078|MetaCyc: PWY-5079|MetaCyc: PWY-5082|MetaCyc: PWY-5480|MetaCyc: PWY-5486|MetaCyc: PWY-5751|MetaCyc: PWY-6313|MetaCyc: PWY-6333|MetaCyc: PWY-6342|MetaCyc: PWY-6587|MetaCyc: PWY-6802|MetaCyc: PWY-6871|MetaCyc: PWY-7013|MetaCyc: PWY-7111|MetaCyc: PWY-7118|MetaCyc: PWY-7396 ALX04_RS11470 19ab50d0bcf00ccc973ca299b50c3320 867 Gene3D G3DSA:1.20.1090.10 648 866 8.7E-55 T 28-03-2018 ALX04_RS11470 19ab50d0bcf00ccc973ca299b50c3320 867 Gene3D G3DSA:3.40.309.10 235 410 1.1E-26 T 28-03-2018 ALX04_RS13805 567099d1023a04d47e031601593ea047 320 PIRSF PIRSF000102 4 320 3.0E-105 T 28-03-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 ALX04_RS13805 567099d1023a04d47e031601593ea047 320 ProSitePatterns PS00064 L-lactate dehydrogenase active site. 176 182 - T 28-03-2018 IPR018177 L-lactate dehydrogenase, active site GO:0004459|GO:0055114 KEGG: 00010+1.1.1.27|KEGG: 00270+1.1.1.27|KEGG: 00620+1.1.1.27|KEGG: 00640+1.1.1.27|MetaCyc: PWY-5481|MetaCyc: PWY-6901|Reactome: R-HSA-70268 ALX04_RS13805 567099d1023a04d47e031601593ea047 320 SUPERFAMILY SSF51735 5 148 1.02E-54 T 28-03-2018 IPR016040 NAD(P)-binding domain ALX04_RS13805 567099d1023a04d47e031601593ea047 320 Gene3D G3DSA:3.90.110.10 147 319 2.1E-46 T 28-03-2018 ALX04_RS13805 567099d1023a04d47e031601593ea047 320 Gene3D G3DSA:3.40.50.720 8 146 1.8E-33 T 28-03-2018 ALX04_RS13805 567099d1023a04d47e031601593ea047 320 SUPERFAMILY SSF56327 147 311 9.22E-54 T 28-03-2018 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 ALX04_RS13805 567099d1023a04d47e031601593ea047 320 PRINTS PR00086 L-lactate dehydrogenase signature 144 162 1.5E-45 T 28-03-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 ALX04_RS13805 567099d1023a04d47e031601593ea047 320 PRINTS PR00086 L-lactate dehydrogenase signature 9 33 1.5E-45 T 28-03-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 ALX04_RS13805 567099d1023a04d47e031601593ea047 320 PRINTS PR00086 L-lactate dehydrogenase signature 120 140 1.5E-45 T 28-03-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 ALX04_RS13805 567099d1023a04d47e031601593ea047 320 PRINTS PR00086 L-lactate dehydrogenase signature 34 58 1.5E-45 T 28-03-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 ALX04_RS13805 567099d1023a04d47e031601593ea047 320 PRINTS PR00086 L-lactate dehydrogenase signature 174 187 1.5E-45 T 28-03-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 ALX04_RS13805 567099d1023a04d47e031601593ea047 320 Hamap MF_00488 L-lactate dehydrogenase [ldh]. 7 314 46.0 T 28-03-2018 IPR011304 L-lactate dehydrogenase GO:0004459|GO:0005737|GO:0055114 KEGG: 00010+1.1.1.27|KEGG: 00270+1.1.1.27|KEGG: 00620+1.1.1.27|KEGG: 00640+1.1.1.27|MetaCyc: PWY-5481|MetaCyc: PWY-6901|Reactome: R-HSA-70268 ALX04_RS13805 567099d1023a04d47e031601593ea047 320 TIGRFAM TIGR01771 L-LDH-NAD: L-lactate dehydrogenase 12 308 3.4E-130 T 28-03-2018 IPR011304 L-lactate dehydrogenase GO:0004459|GO:0005737|GO:0055114 KEGG: 00010+1.1.1.27|KEGG: 00270+1.1.1.27|KEGG: 00620+1.1.1.27|KEGG: 00640+1.1.1.27|MetaCyc: PWY-5481|MetaCyc: PWY-6901|Reactome: R-HSA-70268 ALX04_RS13805 567099d1023a04d47e031601593ea047 320 Pfam PF00056 lactate/malate dehydrogenase, NAD binding domain 9 146 4.4E-48 T 28-03-2018 IPR001236 Lactate/malate dehydrogenase, N-terminal GO:0016491|GO:0055114 ALX04_RS13805 567099d1023a04d47e031601593ea047 320 Pfam PF02866 lactate/malate dehydrogenase, alpha/beta C-terminal domain 149 316 2.0E-42 T 28-03-2018 IPR022383 Lactate/malate dehydrogenase, C-terminal GO:0016616|GO:0055114 ALX04_RS12310 7f5c9e1bf5ce6556a35f8d63b57e9845 557 Gene3D G3DSA:3.20.20.470 1 104 6.3E-35 T 28-03-2018 ALX04_RS12310 7f5c9e1bf5ce6556a35f8d63b57e9845 557 Gene3D G3DSA:3.20.20.470 172 354 1.0E-28 T 28-03-2018 ALX04_RS12310 7f5c9e1bf5ce6556a35f8d63b57e9845 557 Gene3D G3DSA:3.20.20.80 355 478 7.6E-15 T 28-03-2018 ALX04_RS12310 7f5c9e1bf5ce6556a35f8d63b57e9845 557 SUPERFAMILY SSF51011 486 554 9.0E-5 T 28-03-2018 ALX04_RS12310 7f5c9e1bf5ce6556a35f8d63b57e9845 557 SUPERFAMILY SSF51445 3 478 1.04E-123 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily ALX04_RS12310 7f5c9e1bf5ce6556a35f8d63b57e9845 557 Pfam PF00128 Alpha amylase, catalytic domain 28 385 4.2E-98 T 28-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 ALX04_RS12310 7f5c9e1bf5ce6556a35f8d63b57e9845 557 Gene3D G3DSA:2.60.40.1180 485 557 5.9E-7 T 28-03-2018 ALX04_RS12310 7f5c9e1bf5ce6556a35f8d63b57e9845 557 Gene3D G3DSA:3.90.400.10 105 171 1.8E-27 T 28-03-2018 ALX04_RS12310 7f5c9e1bf5ce6556a35f8d63b57e9845 557 SMART SM00642 13 409 1.9E-114 T 28-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 ALX04_RS12715 7061552c43d9905ce9acd85a24131b5a 653 SUPERFAMILY SSF55604 181 255 3.79E-20 T 28-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 ALX04_RS12715 7061552c43d9905ce9acd85a24131b5a 653 SUPERFAMILY SSF51261 4 138 1.01E-45 T 28-03-2018 IPR011055 Duplicated hybrid motif ALX04_RS12715 7061552c43d9905ce9acd85a24131b5a 653 Pfam PF00367 phosphotransferase system, EIIB 184 214 1.0E-12 T 28-03-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 ALX04_RS12715 7061552c43d9905ce9acd85a24131b5a 653 Gene3D G3DSA:2.70.70.10 2 160 3.1E-49 T 28-03-2018 ALX04_RS12715 7061552c43d9905ce9acd85a24131b5a 653 ProSitePatterns PS01035 PTS EIIB domains cysteine phosphorylation site signature. 194 211 - T 28-03-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 ALX04_RS12715 7061552c43d9905ce9acd85a24131b5a 653 Pfam PF00358 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 8 131 3.5E-44 T 28-03-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 ALX04_RS12715 7061552c43d9905ce9acd85a24131b5a 653 TIGRFAM TIGR00830 PTBA: PTS system, glucose subfamily, IIA component 9 129 3.9E-38 T 28-03-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 ALX04_RS12715 7061552c43d9905ce9acd85a24131b5a 653 ProSitePatterns PS00371 PTS EIIA domains phosphorylation site signature 1. 71 83 - T 28-03-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 ALX04_RS12715 7061552c43d9905ce9acd85a24131b5a 653 Pfam PF02378 Phosphotransferase system, EIIC 295 576 2.6E-35 T 28-03-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 ALX04_RS12715 7061552c43d9905ce9acd85a24131b5a 653 Gene3D G3DSA:3.30.1360.60 179 255 2.3E-25 T 28-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 ALX04_RS00875 03b5b2586f6ec5810ca1189c6787a4f8 106 Pfam PF02686 Glu-tRNAGln amidotransferase C subunit 22 95 1.6E-18 T 28-03-2018 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 ALX04_RS00875 03b5b2586f6ec5810ca1189c6787a4f8 106 Hamap MF_00122 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C [gatC]. 5 100 24.205 T 28-03-2018 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 ALX04_RS00875 03b5b2586f6ec5810ca1189c6787a4f8 106 TIGRFAM TIGR00135 gatC: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, C subunit 6 100 5.6E-26 T 28-03-2018 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 ALX04_RS00875 03b5b2586f6ec5810ca1189c6787a4f8 106 SUPERFAMILY SSF141000 5 98 3.66E-25 T 28-03-2018 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 ALX04_RS00440 7bd402b2e65fee11ae48dedff370543a 180 SUPERFAMILY SSF55282 4 179 2.31E-73 T 28-03-2018 IPR022803 Ribosomal protein L5 domain Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 ALX04_RS00440 7bd402b2e65fee11ae48dedff370543a 180 Pfam PF00673 ribosomal L5P family C-terminus 86 178 1.3E-38 T 28-03-2018 IPR031309 Ribosomal protein L5, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 ALX04_RS00440 7bd402b2e65fee11ae48dedff370543a 180 PIRSF PIRSF002161 1 180 2.4E-63 T 28-03-2018 IPR002132 Ribosomal protein L5 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 ALX04_RS00440 7bd402b2e65fee11ae48dedff370543a 180 Hamap MF_01333_B 50S ribosomal protein L5 [rplE]. 2 180 43.991 T 28-03-2018 IPR020930 Ribosomal protein L5, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 ALX04_RS00440 7bd402b2e65fee11ae48dedff370543a 180 Gene3D G3DSA:3.30.1440.10 2 180 5.2E-76 T 28-03-2018 IPR022803 Ribosomal protein L5 domain Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 ALX04_RS00440 7bd402b2e65fee11ae48dedff370543a 180 Pfam PF00281 Ribosomal protein L5 25 81 2.1E-26 T 28-03-2018 IPR031310 Ribosomal protein L5, N-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 ALX04_RS00440 7bd402b2e65fee11ae48dedff370543a 180 ProSitePatterns PS00358 Ribosomal protein L5 signature. 58 74 - T 28-03-2018 IPR020929 Ribosomal protein L5, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 ALX04_RS07105 03b16259787c3a20ffae02069dffc679 133 SUPERFAMILY SSF55021 45 127 8.48E-18 T 28-03-2018 ALX04_RS07105 03b16259787c3a20ffae02069dffc679 133 Hamap MF_01054 UPF0237 protein . 45 133 24.336 T 28-03-2018 IPR022986 Uncharacterised protein family UPF0237, ACT-type ALX04_RS07105 03b16259787c3a20ffae02069dffc679 133 Pfam PF13740 ACT domain 48 121 8.6E-10 T 28-03-2018 ALX04_RS07105 03b16259787c3a20ffae02069dffc679 133 Gene3D G3DSA:3.30.70.260 36 133 5.3E-18 T 28-03-2018 ALX04_RS02600 2448e03e56c481f469f153cc9a88b4cf 320 ProSitePatterns PS01125 ROK family signature. 139 166 - T 28-03-2018 IPR000600 ROK family Reactome: R-HSA-4085001 ALX04_RS02600 2448e03e56c481f469f153cc9a88b4cf 320 TIGRFAM TIGR00744 ROK_glcA_fam: ROK family protein (putative glucokinase) 6 318 9.6E-98 T 28-03-2018 IPR004654 Glucokinase ROK GO:0004340|GO:0005737|GO:0006096|GO:0051156 KEGG: 00010+2.7.1.2|KEGG: 00052+2.7.1.2|KEGG: 00500+2.7.1.2|KEGG: 00520+2.7.1.2|KEGG: 00521+2.7.1.2|KEGG: 00524+2.7.1.2|MetaCyc: PWY-2722|MetaCyc: PWY-2723|MetaCyc: PWY-5514|MetaCyc: PWY-5661|MetaCyc: PWY-621|MetaCyc: PWY-7238|MetaCyc: PWY-7385 ALX04_RS02600 2448e03e56c481f469f153cc9a88b4cf 320 SUPERFAMILY SSF53067 4 318 2.49E-68 T 28-03-2018 ALX04_RS02600 2448e03e56c481f469f153cc9a88b4cf 320 Gene3D G3DSA:3.30.420.40 129 319 1.4E-58 T 28-03-2018 ALX04_RS02600 2448e03e56c481f469f153cc9a88b4cf 320 Gene3D G3DSA:3.30.420.40 2 128 1.2E-27 T 28-03-2018 ALX04_RS02600 2448e03e56c481f469f153cc9a88b4cf 320 Pfam PF00480 ROK family 6 318 6.2E-73 T 28-03-2018 IPR000600 ROK family Reactome: R-HSA-4085001 ALX04_RS09230 c3fc7978889c6ba6e439e36d7a6e3fea 460 Pfam PF00232 Glycosyl hydrolase family 1 5 457 3.5E-121 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 ALX04_RS09230 c3fc7978889c6ba6e439e36d7a6e3fea 460 Gene3D G3DSA:3.20.20.80 2 460 2.7E-126 T 28-03-2018 ALX04_RS09230 c3fc7978889c6ba6e439e36d7a6e3fea 460 SUPERFAMILY SSF51445 6 457 2.21E-136 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily ALX04_RS09230 c3fc7978889c6ba6e439e36d7a6e3fea 460 PRINTS PR00131 Glycosyl hydrolase family 1 signature 376 387 2.8E-12 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 ALX04_RS09230 c3fc7978889c6ba6e439e36d7a6e3fea 460 PRINTS PR00131 Glycosyl hydrolase family 1 signature 422 434 2.8E-12 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 ALX04_RS09230 c3fc7978889c6ba6e439e36d7a6e3fea 460 PRINTS PR00131 Glycosyl hydrolase family 1 signature 398 415 2.8E-12 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 ALX04_RS09230 c3fc7978889c6ba6e439e36d7a6e3fea 460 PRINTS PR00131 Glycosyl hydrolase family 1 signature 355 363 2.8E-12 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 ALX04_RS09230 c3fc7978889c6ba6e439e36d7a6e3fea 460 PRINTS PR00131 Glycosyl hydrolase family 1 signature 287 301 2.8E-12 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 ALX04_RS10440 4984b37f748bfd6294e5770a062961e2 614 Gene3D G3DSA:2.70.150.10 23 211 2.4E-28 T 28-03-2018 ALX04_RS10440 4984b37f748bfd6294e5770a062961e2 614 Gene3D G3DSA:3.40.50.1000 267 547 2.1E-44 T 28-03-2018 IPR023214 HAD-like domain ALX04_RS10440 4984b37f748bfd6294e5770a062961e2 614 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 489 505 1.3E-7 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 ALX04_RS10440 4984b37f748bfd6294e5770a062961e2 614 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 521 546 1.3E-7 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 ALX04_RS10440 4984b37f748bfd6294e5770a062961e2 614 SUPERFAMILY SSF56784 357 589 1.56E-45 T 28-03-2018 IPR023214 HAD-like domain ALX04_RS10440 4984b37f748bfd6294e5770a062961e2 614 SUPERFAMILY SSF56784 302 320 1.56E-45 T 28-03-2018 IPR023214 HAD-like domain ALX04_RS10440 4984b37f748bfd6294e5770a062961e2 614 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 304 310 - T 28-03-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 ALX04_RS10440 4984b37f748bfd6294e5770a062961e2 614 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 83 577 2.8E-68 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 ALX04_RS10440 4984b37f748bfd6294e5770a062961e2 614 SUPERFAMILY SSF81665 211 296 5.36E-6 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 ALX04_RS10440 4984b37f748bfd6294e5770a062961e2 614 SUPERFAMILY SSF81665 66 111 5.36E-6 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 ALX04_RS10440 4984b37f748bfd6294e5770a062961e2 614 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 302 316 8.0E-28 T 28-03-2018 ALX04_RS10440 4984b37f748bfd6294e5770a062961e2 614 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 413 424 8.0E-28 T 28-03-2018 ALX04_RS10440 4984b37f748bfd6294e5770a062961e2 614 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 436 446 8.0E-28 T 28-03-2018 ALX04_RS10440 4984b37f748bfd6294e5770a062961e2 614 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 513 525 8.0E-28 T 28-03-2018 ALX04_RS10440 4984b37f748bfd6294e5770a062961e2 614 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 160 174 8.0E-28 T 28-03-2018 ALX04_RS10440 4984b37f748bfd6294e5770a062961e2 614 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 489 508 8.0E-28 T 28-03-2018 ALX04_RS10440 4984b37f748bfd6294e5770a062961e2 614 Pfam PF00702 haloacid dehalogenase-like hydrolase 301 503 8.2E-31 T 28-03-2018 ALX04_RS10440 4984b37f748bfd6294e5770a062961e2 614 Pfam PF00122 E1-E2 ATPase 112 281 2.9E-41 T 28-03-2018 ALX04_RS10440 4984b37f748bfd6294e5770a062961e2 614 TIGRFAM TIGR01512 ATPase-IB2_Cd: cadmium-translocating P-type ATPase 60 594 1.5E-154 T 28-03-2018 ALX04_RS10440 4984b37f748bfd6294e5770a062961e2 614 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 60 591 1.2E-159 T 28-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 ALX04_RS10440 4984b37f748bfd6294e5770a062961e2 614 SUPERFAMILY SSF81653 113 210 8.76E-23 T 28-03-2018 IPR008250 P-type ATPase, A domain Reactome: R-HSA-936837 ALX04_RS09145 9df45b5592d29bb60b51c4885ae52e74 143 Pfam PF00582 Universal stress protein family 5 143 6.0E-25 T 28-03-2018 IPR006016 UspA GO:0006950 ALX04_RS09145 9df45b5592d29bb60b51c4885ae52e74 143 Gene3D G3DSA:3.40.50.620 1 143 8.9E-27 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold ALX04_RS09145 9df45b5592d29bb60b51c4885ae52e74 143 SUPERFAMILY SSF52402 5 143 1.76E-26 T 28-03-2018 ALX04_RS09145 9df45b5592d29bb60b51c4885ae52e74 143 PRINTS PR01438 Universal stress protein signature 121 143 3.6E-7 T 28-03-2018 IPR006015 Universal stress protein A ALX04_RS09145 9df45b5592d29bb60b51c4885ae52e74 143 PRINTS PR01438 Universal stress protein signature 104 116 3.6E-7 T 28-03-2018 IPR006015 Universal stress protein A ALX04_RS09145 9df45b5592d29bb60b51c4885ae52e74 143 PRINTS PR01438 Universal stress protein signature 5 23 3.6E-7 T 28-03-2018 IPR006015 Universal stress protein A ALX04_RS13815 4fafd33ff0096a548a255e9651770a19 1175 SUPERFAMILY SSF52540 21 348 8.67E-80 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase ALX04_RS13815 4fafd33ff0096a548a255e9651770a19 1175 SMART SM01058 495 592 1.3E-51 T 28-03-2018 IPR003711 CarD-like/TRCF domain ALX04_RS13815 4fafd33ff0096a548a255e9651770a19 1175 TIGRFAM TIGR00580 mfd: transcription-repair coupling factor 155 1092 0.0 T 28-03-2018 IPR004576 Transcription-repair coupling factor GO:0003684|GO:0005524|GO:0006281 ALX04_RS13815 4fafd33ff0096a548a255e9651770a19 1175 Pfam PF00271 Helicase conserved C-terminal domain 824 925 2.1E-14 T 28-03-2018 IPR001650 Helicase, C-terminal ALX04_RS13815 4fafd33ff0096a548a255e9651770a19 1175 SUPERFAMILY SSF141259 487 564 1.57E-25 T 28-03-2018 IPR003711 CarD-like/TRCF domain ALX04_RS13815 4fafd33ff0096a548a255e9651770a19 1175 SMART SM00490 842 926 1.5E-16 T 28-03-2018 IPR001650 Helicase, C-terminal ALX04_RS13815 4fafd33ff0096a548a255e9651770a19 1175 SMART SM00982 1019 1119 3.5E-36 T 28-03-2018 IPR005118 Transcription-repair-coupling factor, C-terminal domain GO:0006281 ALX04_RS13815 4fafd33ff0096a548a255e9651770a19 1175 Pfam PF00270 DEAD/DEAH box helicase 621 780 6.1E-16 T 28-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 ALX04_RS13815 4fafd33ff0096a548a255e9651770a19 1175 Hamap MF_00969 Transcription-repair-coupling factor [mfd]. 40 1126 29.313 T 28-03-2018 IPR004576 Transcription-repair coupling factor GO:0003684|GO:0005524|GO:0006281 ALX04_RS13815 4fafd33ff0096a548a255e9651770a19 1175 Pfam PF03461 TRCF domain 1020 1110 5.2E-26 T 28-03-2018 IPR005118 Transcription-repair-coupling factor, C-terminal domain GO:0006281 ALX04_RS13815 4fafd33ff0096a548a255e9651770a19 1175 Gene3D G3DSA:3.40.50.300 805 972 1.3E-22 T 28-03-2018 ALX04_RS13815 4fafd33ff0096a548a255e9651770a19 1175 Pfam PF02559 CarD-like/TRCF domain 496 591 6.5E-31 T 28-03-2018 IPR003711 CarD-like/TRCF domain ALX04_RS13815 4fafd33ff0096a548a255e9651770a19 1175 SUPERFAMILY SSF52540 540 799 1.55E-64 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase ALX04_RS13815 4fafd33ff0096a548a255e9651770a19 1175 SUPERFAMILY SSF52540 798 1003 8.27E-44 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase ALX04_RS13815 4fafd33ff0096a548a255e9651770a19 1175 SUPERFAMILY SSF52540 375 485 2.3E-22 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase ALX04_RS13815 4fafd33ff0096a548a255e9651770a19 1175 SUPERFAMILY SSF143517 1005 1162 7.72E-34 T 28-03-2018 ALX04_RS13815 4fafd33ff0096a548a255e9651770a19 1175 Gene3D G3DSA:3.40.50.300 26 288 0.37 T 28-03-2018 ALX04_RS13815 4fafd33ff0096a548a255e9651770a19 1175 Gene3D G3DSA:3.40.50.300 289 786 8.1E-39 T 28-03-2018 ALX04_RS13815 4fafd33ff0096a548a255e9651770a19 1175 SMART SM00487 616 806 3.7E-37 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain ALX04_RS15505 8ead3858e414d85578e5efac6ab81aa0 104 ProSitePatterns PS00194 Thioredoxin family active site. 20 38 - T 28-03-2018 IPR017937 Thioredoxin, conserved site GO:0045454 ALX04_RS15505 8ead3858e414d85578e5efac6ab81aa0 104 PIRSF PIRSF000077 1 103 1.6E-35 T 28-03-2018 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 ALX04_RS15505 8ead3858e414d85578e5efac6ab81aa0 104 TIGRFAM TIGR01068 thioredoxin: thioredoxin 6 102 2.3E-32 T 28-03-2018 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 ALX04_RS15505 8ead3858e414d85578e5efac6ab81aa0 104 Gene3D G3DSA:3.40.30.10 1 104 2.7E-30 T 28-03-2018 ALX04_RS15505 8ead3858e414d85578e5efac6ab81aa0 104 Pfam PF00085 Thioredoxin 2 100 1.8E-25 T 28-03-2018 IPR013766 Thioredoxin domain GO:0045454 ALX04_RS15505 8ead3858e414d85578e5efac6ab81aa0 104 SUPERFAMILY SSF52833 2 103 1.85E-32 T 28-03-2018 IPR012336 Thioredoxin-like fold ALX04_RS15505 8ead3858e414d85578e5efac6ab81aa0 104 PRINTS PR00421 Thioredoxin family signature 27 36 3.3E-5 T 28-03-2018 ALX04_RS15505 8ead3858e414d85578e5efac6ab81aa0 104 PRINTS PR00421 Thioredoxin family signature 19 27 3.3E-5 T 28-03-2018 ALX04_RS15505 8ead3858e414d85578e5efac6ab81aa0 104 PRINTS PR00421 Thioredoxin family signature 67 78 3.3E-5 T 28-03-2018 ALX04_RS01880 28355e9c390229e681a0f4b880f7b024 207 TIGRFAM TIGR00455 apsK: adenylyl-sulfate kinase 9 193 8.6E-85 T 28-03-2018 IPR002891 Adenylyl-sulfate kinase GO:0000103|GO:0004020|GO:0005524 KEGG: 00230+2.7.1.25|KEGG: 00920+2.7.1.25|MetaCyc: PWY-5340|Reactome: R-HSA-174362|Reactome: R-HSA-2408550 ALX04_RS01880 28355e9c390229e681a0f4b880f7b024 207 SUPERFAMILY SSF52540 22 195 6.28E-39 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase ALX04_RS01880 28355e9c390229e681a0f4b880f7b024 207 Hamap MF_00065 Adenylyl-sulfate kinase [cysC]. 25 197 37.901 T 28-03-2018 IPR002891 Adenylyl-sulfate kinase GO:0000103|GO:0004020|GO:0005524 KEGG: 00230+2.7.1.25|KEGG: 00920+2.7.1.25|MetaCyc: PWY-5340|Reactome: R-HSA-174362|Reactome: R-HSA-2408550 ALX04_RS01880 28355e9c390229e681a0f4b880f7b024 207 Gene3D G3DSA:3.40.50.300 22 201 4.3E-52 T 28-03-2018 ALX04_RS01880 28355e9c390229e681a0f4b880f7b024 207 Pfam PF01583 Adenylylsulphate kinase 26 180 3.0E-73 T 28-03-2018 ALX04_RS05975 35ca2223509c963dbb7e6c4796bfd08d 273 ProSitePatterns PS00923 Aspartate and glutamate racemases signature 1. 71 79 - T 28-03-2018 IPR018187 Asp/Glu racemase, active site 1 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 ALX04_RS05975 35ca2223509c963dbb7e6c4796bfd08d 273 Gene3D G3DSA:3.40.50.1860 3 114 4.1E-26 T 28-03-2018 ALX04_RS05975 35ca2223509c963dbb7e6c4796bfd08d 273 SUPERFAMILY SSF53681 6 108 3.27E-33 T 28-03-2018 IPR001920 Asp/Glu racemase GO:0008152|GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 ALX04_RS05975 35ca2223509c963dbb7e6c4796bfd08d 273 Hamap MF_00258 Glutamate racemase [murI]. 5 258 40.056 T 28-03-2018 IPR004391 Glutamate racemase GO:0008881|GO:0009252 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 ALX04_RS05975 35ca2223509c963dbb7e6c4796bfd08d 273 SUPERFAMILY SSF53681 111 264 6.38E-41 T 28-03-2018 IPR001920 Asp/Glu racemase GO:0008152|GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 ALX04_RS05975 35ca2223509c963dbb7e6c4796bfd08d 273 TIGRFAM TIGR00067 glut_race: glutamate racemase 7 256 3.7E-76 T 28-03-2018 IPR004391 Glutamate racemase GO:0008881|GO:0009252 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 ALX04_RS05975 35ca2223509c963dbb7e6c4796bfd08d 273 Pfam PF01177 Asp/Glu/Hydantoin racemase 7 215 3.5E-36 T 28-03-2018 IPR015942 Asp/Glu/hydantoin racemase GO:0006807|GO:0036361 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 ALX04_RS05975 35ca2223509c963dbb7e6c4796bfd08d 273 Gene3D G3DSA:3.40.50.1860 115 270 7.5E-44 T 28-03-2018 ALX04_RS05975 35ca2223509c963dbb7e6c4796bfd08d 273 ProSitePatterns PS00924 Aspartate and glutamate racemases signature 2. 181 191 - T 28-03-2018 IPR033134 Asp/Glu racemase, active site 2 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 ALX04_RS01695 e6832b41404fed4103443d5ae9df4335 450 Pfam PF13416 Bacterial extracellular solute-binding protein 56 374 7.9E-34 T 28-03-2018 ALX04_RS01695 e6832b41404fed4103443d5ae9df4335 450 Gene3D G3DSA:3.40.190.10 159 441 1.2E-39 T 28-03-2018 ALX04_RS01695 e6832b41404fed4103443d5ae9df4335 450 SUPERFAMILY SSF53850 39 436 1.85E-64 T 28-03-2018 ALX04_RS01695 e6832b41404fed4103443d5ae9df4335 450 Gene3D G3DSA:3.40.190.10 38 158 4.0E-8 T 28-03-2018 ALX04_RS13315 38782ec0ca6f714da73e77f226cd9018 263 Pfam PF08282 haloacid dehalogenase-like hydrolase 6 257 1.0E-51 T 28-03-2018 IPR023214 HAD-like domain ALX04_RS13315 38782ec0ca6f714da73e77f226cd9018 263 SUPERFAMILY SSF56784 1 261 4.45E-63 T 28-03-2018 IPR023214 HAD-like domain ALX04_RS13315 38782ec0ca6f714da73e77f226cd9018 263 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 4 230 1.5E-20 T 28-03-2018 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 ALX04_RS13315 38782ec0ca6f714da73e77f226cd9018 263 ProSitePatterns PS01229 Hypothetical cof family signature 2. 211 233 - T 28-03-2018 ALX04_RS13315 38782ec0ca6f714da73e77f226cd9018 263 Gene3D G3DSA:3.40.50.1000 1 263 1.9E-31 T 28-03-2018 IPR023214 HAD-like domain ALX04_RS13315 38782ec0ca6f714da73e77f226cd9018 263 TIGRFAM TIGR00099 Cof-subfamily: Cof-like hydrolase 5 257 8.0E-49 T 28-03-2018 IPR000150 Cof family GO:0016787 ALX04_RS11405 2ec5cfaf69db8efb9a345d3b453e6bce 584 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 196 324 1.9E-27 T 28-03-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 ALX04_RS11405 2ec5cfaf69db8efb9a345d3b453e6bce 584 Gene3D G3DSA:3.40.50.970 347 546 6.0E-27 T 28-03-2018 ALX04_RS11405 2ec5cfaf69db8efb9a345d3b453e6bce 584 Gene3D G3DSA:3.40.50.1220 195 346 1.9E-35 T 28-03-2018 IPR029035 DHS-like NAD/FAD-binding domain ALX04_RS11405 2ec5cfaf69db8efb9a345d3b453e6bce 584 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 384 526 1.7E-29 T 28-03-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 ALX04_RS11405 2ec5cfaf69db8efb9a345d3b453e6bce 584 Gene3D G3DSA:3.40.50.970 1 194 1.7E-37 T 28-03-2018 ALX04_RS11405 2ec5cfaf69db8efb9a345d3b453e6bce 584 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 7 173 1.2E-38 T 28-03-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 ALX04_RS11405 2ec5cfaf69db8efb9a345d3b453e6bce 584 SUPERFAMILY SSF52518 2 175 9.38E-41 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold ALX04_RS11405 2ec5cfaf69db8efb9a345d3b453e6bce 584 SUPERFAMILY SSF52467 188 357 1.71E-37 T 28-03-2018 IPR029035 DHS-like NAD/FAD-binding domain ALX04_RS11405 2ec5cfaf69db8efb9a345d3b453e6bce 584 SUPERFAMILY SSF52518 360 559 4.59E-46 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold ALX04_RS11405 2ec5cfaf69db8efb9a345d3b453e6bce 584 ProSitePatterns PS00187 Thiamine pyrophosphate enzymes signature. 421 440 - T 28-03-2018 IPR000399 TPP-binding enzyme, conserved site GO:0000287|GO:0030976 ALX04_RS09225 a817c62c2cd440b7910000ed3943c508 490 PIRSF PIRSF006351 6 482 4.6E-132 T 28-03-2018 IPR004796 Phosphotransferase system, cellobiose-type IIC component GO:0008982|GO:0009401|GO:0016021 ALX04_RS09225 a817c62c2cd440b7910000ed3943c508 490 TIGRFAM TIGR00410 lacE: PTS system, lactose/cellobiose family IIC component 170 473 3.0E-83 T 28-03-2018 IPR004501 Phosphotransferase system, EIIC component, type 3 GO:0008982|GO:0009401|GO:0016021 ALX04_RS09225 a817c62c2cd440b7910000ed3943c508 490 Pfam PF02378 Phosphotransferase system, EIIC 35 400 2.4E-66 T 28-03-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 ALX04_RS03025 f05da064b6d268cf9be27dcb75767d9a 328 Gene3D G3DSA:3.40.47.10 160 328 1.8E-36 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 ALX04_RS03025 f05da064b6d268cf9be27dcb75767d9a 328 Hamap MF_01815 3-oxoacyl-[acyl-carrier-protein] synthase 3 [fabH]. 3 328 62.714 T 28-03-2018 IPR004655 3-oxoacyl-[acyl-carrier-protein] synthase 3 GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 ALX04_RS03025 f05da064b6d268cf9be27dcb75767d9a 328 Gene3D G3DSA:3.40.47.10 2 159 2.5E-27 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 ALX04_RS03025 f05da064b6d268cf9be27dcb75767d9a 328 TIGRFAM TIGR00747 fabH: 3-oxoacyl-[acyl-carrier-protein] synthase III 5 327 5.1E-90 T 28-03-2018 IPR004655 3-oxoacyl-[acyl-carrier-protein] synthase 3 GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 ALX04_RS03025 f05da064b6d268cf9be27dcb75767d9a 328 Pfam PF08545 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III 107 177 4.7E-25 T 28-03-2018 IPR013751 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 ALX04_RS03025 f05da064b6d268cf9be27dcb75767d9a 328 SUPERFAMILY SSF53901 4 327 3.59E-55 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 ALX04_RS03025 f05da064b6d268cf9be27dcb75767d9a 328 Pfam PF08541 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal 239 328 8.9E-31 T 28-03-2018 IPR013747 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III, C-terminal KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 ALX04_RS09080 d1dc042c0ce33ce8cf377ebbaf9b04f5 347 Pfam PF11797 Protein of unknown function C-terminal (DUF3324) 171 304 8.7E-41 T 28-03-2018 IPR021759 Domain of unknown function DUF3324, C-terminal ALX04_RS09080 d1dc042c0ce33ce8cf377ebbaf9b04f5 347 Gene3D G3DSA:2.60.40.1710 46 174 4.4E-9 T 28-03-2018 ALX04_RS09080 d1dc042c0ce33ce8cf377ebbaf9b04f5 347 Pfam PF06030 Bacterial protein of unknown function (DUF916) 37 157 3.7E-38 T 28-03-2018 IPR010317 Protein of unknown function DUF916, cell surface putative ALX04_RS09080 d1dc042c0ce33ce8cf377ebbaf9b04f5 347 Gene3D G3DSA:1.20.5.100 306 347 4.2E-4 T 28-03-2018 ALX04_RS06085 f1ecc3d9a7cbe76319d514c36fad4b6c 678 SMART SM01340 207 325 3.3E-47 T 28-03-2018 IPR013507 DNA mismatch repair protein, C-terminal GO:0005524|GO:0006298|GO:0030983 ALX04_RS06085 f1ecc3d9a7cbe76319d514c36fad4b6c 678 SUPERFAMILY SSF54211 188 324 1.21E-32 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold ALX04_RS06085 f1ecc3d9a7cbe76319d514c36fad4b6c 678 ProSitePatterns PS00058 DNA mismatch repair proteins mutL / hexB / PMS1 signature. 94 100 - T 28-03-2018 IPR014762 DNA mismatch repair, conserved site ALX04_RS06085 f1ecc3d9a7cbe76319d514c36fad4b6c 678 Gene3D G3DSA:3.30.230.10 194 323 8.7E-26 T 28-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup ALX04_RS06085 f1ecc3d9a7cbe76319d514c36fad4b6c 678 SUPERFAMILY SSF118116 480 669 1.07E-54 T 28-03-2018 ALX04_RS06085 f1ecc3d9a7cbe76319d514c36fad4b6c 678 Hamap MF_00149 DNA mismatch repair protein MutL [mutL]. 2 667 26.126 T 28-03-2018 IPR020667 DNA mismatch repair protein, MutL GO:0006298 ALX04_RS06085 f1ecc3d9a7cbe76319d514c36fad4b6c 678 Pfam PF08676 MutL C terminal dimerisation domain 483 627 1.1E-44 T 28-03-2018 IPR014790 MutL, C-terminal, dimerisation GO:0005524|GO:0006298 ALX04_RS06085 f1ecc3d9a7cbe76319d514c36fad4b6c 678 TIGRFAM TIGR00585 mutl: DNA mismatch repair protein MutL 3 305 1.3E-94 T 28-03-2018 IPR002099 DNA mismatch repair protein family GO:0005524|GO:0006298|GO:0030983 ALX04_RS06085 f1ecc3d9a7cbe76319d514c36fad4b6c 678 SMART SM00853 485 627 8.0E-54 T 28-03-2018 IPR014790 MutL, C-terminal, dimerisation GO:0005524|GO:0006298 ALX04_RS06085 f1ecc3d9a7cbe76319d514c36fad4b6c 678 Pfam PF13589 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 25 85 4.1E-12 T 28-03-2018 ALX04_RS06085 f1ecc3d9a7cbe76319d514c36fad4b6c 678 Gene3D G3DSA:3.30.565.10 8 193 2.8E-29 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain ALX04_RS06085 f1ecc3d9a7cbe76319d514c36fad4b6c 678 Pfam PF01119 DNA mismatch repair protein, C-terminal domain 207 324 3.7E-34 T 28-03-2018 IPR013507 DNA mismatch repair protein, C-terminal GO:0005524|GO:0006298|GO:0030983 ALX04_RS06085 f1ecc3d9a7cbe76319d514c36fad4b6c 678 SUPERFAMILY SSF55874 3 212 8.51E-50 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain ALX04_RS00635 79bcb3c195eaddc13710e1124a542af3 341 Pfam PF07883 Cupin domain 28 72 3.3E-8 T 28-03-2018 IPR013096 Cupin 2, conserved barrel ALX04_RS00635 79bcb3c195eaddc13710e1124a542af3 341 SUPERFAMILY SSF51182 21 201 4.54E-10 T 28-03-2018 IPR011051 RmlC-like cupin domain ALX04_RS00635 79bcb3c195eaddc13710e1124a542af3 341 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 252 268 2.3E-5 T 28-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 ALX04_RS00635 79bcb3c195eaddc13710e1124a542af3 341 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 237 252 2.3E-5 T 28-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 ALX04_RS00635 79bcb3c195eaddc13710e1124a542af3 341 Pfam PF12833 Helix-turn-helix domain 192 269 7.2E-23 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 ALX04_RS00635 79bcb3c195eaddc13710e1124a542af3 341 SUPERFAMILY SSF46689 221 271 3.27E-11 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 ALX04_RS00635 79bcb3c195eaddc13710e1124a542af3 341 Gene3D G3DSA:2.60.120.10 5 171 2.9E-11 T 28-03-2018 IPR014710 RmlC-like jelly roll fold ALX04_RS00635 79bcb3c195eaddc13710e1124a542af3 341 SMART SM00342 185 268 1.9E-28 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 ALX04_RS00635 79bcb3c195eaddc13710e1124a542af3 341 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 222 264 - T 28-03-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 ALX04_RS00635 79bcb3c195eaddc13710e1124a542af3 341 Gene3D G3DSA:1.10.10.60 218 276 7.5E-13 T 28-03-2018 ALX04_RS00635 79bcb3c195eaddc13710e1124a542af3 341 Gene3D G3DSA:1.10.10.60 172 217 7.9E-16 T 28-03-2018 ALX04_RS04235 b6cef10a51abfd1bef27b9219145e8a1 468 SUPERFAMILY SSF55424 321 444 4.3E-30 T 28-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 ALX04_RS04235 b6cef10a51abfd1bef27b9219145e8a1 468 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 1 305 1.7E-58 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ALX04_RS04235 b6cef10a51abfd1bef27b9219145e8a1 468 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 3 22 1.9E-22 T 28-03-2018 ALX04_RS04235 b6cef10a51abfd1bef27b9219145e8a1 468 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 104 122 1.9E-22 T 28-03-2018 ALX04_RS04235 b6cef10a51abfd1bef27b9219145e8a1 468 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 260 282 1.9E-22 T 28-03-2018 ALX04_RS04235 b6cef10a51abfd1bef27b9219145e8a1 468 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 234 250 1.9E-22 T 28-03-2018 ALX04_RS04235 b6cef10a51abfd1bef27b9219145e8a1 468 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 149 167 1.9E-22 T 28-03-2018 ALX04_RS04235 b6cef10a51abfd1bef27b9219145e8a1 468 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 331 428 1.8E-7 T 28-03-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 ALX04_RS04235 b6cef10a51abfd1bef27b9219145e8a1 468 Gene3D G3DSA:3.50.50.60 253 336 1.4E-11 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ALX04_RS04235 b6cef10a51abfd1bef27b9219145e8a1 468 Gene3D G3DSA:3.50.50.60 1 120 4.7E-14 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ALX04_RS04235 b6cef10a51abfd1bef27b9219145e8a1 468 Gene3D G3DSA:3.30.390.30 337 454 1.4E-17 T 28-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 ALX04_RS04235 b6cef10a51abfd1bef27b9219145e8a1 468 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 2 24 1.5E-12 T 28-03-2018 ALX04_RS04235 b6cef10a51abfd1bef27b9219145e8a1 468 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 275 282 1.5E-12 T 28-03-2018 ALX04_RS04235 b6cef10a51abfd1bef27b9219145e8a1 468 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 235 249 1.5E-12 T 28-03-2018 ALX04_RS04235 b6cef10a51abfd1bef27b9219145e8a1 468 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 149 174 1.5E-12 T 28-03-2018 ALX04_RS04235 b6cef10a51abfd1bef27b9219145e8a1 468 Gene3D G3DSA:3.50.50.60 121 252 9.6E-24 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ALX04_RS04235 b6cef10a51abfd1bef27b9219145e8a1 468 SUPERFAMILY SSF51905 1 317 1.83E-40 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ALX04_RS08870 68ad9958a07a7bcfdfa33ed0f3419b23 80 SMART SM01117 6 78 7.8E-9 T 28-03-2018 IPR001199 Cytochrome b5-like heme/steroid binding domain ALX04_RS08870 68ad9958a07a7bcfdfa33ed0f3419b23 80 Pfam PF00173 Cytochrome b5-like Heme/Steroid binding domain 9 76 8.0E-9 T 28-03-2018 IPR001199 Cytochrome b5-like heme/steroid binding domain ALX04_RS08870 68ad9958a07a7bcfdfa33ed0f3419b23 80 SUPERFAMILY SSF55856 5 69 2.49E-14 T 28-03-2018 IPR001199 Cytochrome b5-like heme/steroid binding domain ALX04_RS08870 68ad9958a07a7bcfdfa33ed0f3419b23 80 Gene3D G3DSA:3.10.120.10 2 76 3.3E-12 T 28-03-2018 IPR001199 Cytochrome b5-like heme/steroid binding domain ALX04_RS03525 ecb8e1c3af02f3f29ecd7250707ff9c1 360 PRINTS PR00096 Glutamine amidotransferase superfamily signature 213 222 3.8E-5 T 28-03-2018 ALX04_RS03525 ecb8e1c3af02f3f29ecd7250707ff9c1 360 PRINTS PR00096 Glutamine amidotransferase superfamily signature 241 252 3.8E-5 T 28-03-2018 ALX04_RS03525 ecb8e1c3af02f3f29ecd7250707ff9c1 360 PRINTS PR00096 Glutamine amidotransferase superfamily signature 327 340 3.8E-5 T 28-03-2018 ALX04_RS03525 ecb8e1c3af02f3f29ecd7250707ff9c1 360 Gene3D G3DSA:3.40.50.880 139 357 4.0E-35 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like ALX04_RS03525 ecb8e1c3af02f3f29ecd7250707ff9c1 360 SUPERFAMILY SSF52317 144 354 3.9E-39 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like ALX04_RS03525 ecb8e1c3af02f3f29ecd7250707ff9c1 360 TIGRFAM TIGR01368 CPSaseIIsmall: carbamoyl-phosphate synthase, small subunit 5 353 4.2E-110 T 28-03-2018 IPR006274 Carbamoyl-phosphate synthase, small subunit GO:0004088|GO:0006207|GO:0006541 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 ALX04_RS03525 ecb8e1c3af02f3f29ecd7250707ff9c1 360 SUPERFAMILY SSF52021 2 140 2.09E-47 T 28-03-2018 IPR002474 Carbamoyl-phosphate synthase small subunit, N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 ALX04_RS03525 ecb8e1c3af02f3f29ecd7250707ff9c1 360 Pfam PF00988 Carbamoyl-phosphate synthase small chain, CPSase domain 4 131 1.5E-42 T 28-03-2018 IPR002474 Carbamoyl-phosphate synthase small subunit, N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 ALX04_RS03525 ecb8e1c3af02f3f29ecd7250707ff9c1 360 Pfam PF00117 Glutamine amidotransferase class-I 172 350 4.3E-27 T 28-03-2018 IPR017926 Glutamine amidotransferase ALX04_RS03525 ecb8e1c3af02f3f29ecd7250707ff9c1 360 SMART SM01097 2 132 5.5E-66 T 28-03-2018 IPR002474 Carbamoyl-phosphate synthase small subunit, N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 ALX04_RS03525 ecb8e1c3af02f3f29ecd7250707ff9c1 360 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 171 185 4.2E-23 T 28-03-2018 ALX04_RS03525 ecb8e1c3af02f3f29ecd7250707ff9c1 360 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 210 224 4.2E-23 T 28-03-2018 ALX04_RS03525 ecb8e1c3af02f3f29ecd7250707ff9c1 360 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 283 294 4.2E-23 T 28-03-2018 ALX04_RS03525 ecb8e1c3af02f3f29ecd7250707ff9c1 360 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 241 257 4.2E-23 T 28-03-2018 ALX04_RS03525 ecb8e1c3af02f3f29ecd7250707ff9c1 360 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 258 275 4.2E-23 T 28-03-2018 ALX04_RS03525 ecb8e1c3af02f3f29ecd7250707ff9c1 360 Gene3D G3DSA:3.50.30.20 1 138 2.1E-47 T 28-03-2018 IPR002474 Carbamoyl-phosphate synthase small subunit, N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 ALX04_RS03525 ecb8e1c3af02f3f29ecd7250707ff9c1 360 Hamap MF_01209 Carbamoyl-phosphate synthase small chain [carA]. 2 356 38.02 T 28-03-2018 IPR006274 Carbamoyl-phosphate synthase, small subunit GO:0004088|GO:0006207|GO:0006541 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 ALX04_RS02785 33c03dd7842a9e16f1c65d3df86e9db0 70 SUPERFAMILY SSF63562 2 68 3.14E-22 T 28-03-2018 IPR006110 RNA polymerase, subunit omega/K/RPB6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708 ALX04_RS02785 33c03dd7842a9e16f1c65d3df86e9db0 70 Pfam PF01192 RNA polymerase Rpb6 9 60 4.1E-12 T 28-03-2018 IPR006110 RNA polymerase, subunit omega/K/RPB6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708 ALX04_RS02785 33c03dd7842a9e16f1c65d3df86e9db0 70 Hamap MF_00366 DNA-directed RNA polymerase subunit omega [rpoZ]. 2 63 15.618 T 28-03-2018 IPR003716 DNA-directed RNA polymerase, omega subunit GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 ALX04_RS02785 33c03dd7842a9e16f1c65d3df86e9db0 70 Gene3D G3DSA:3.90.940.10 1 70 2.2E-22 T 28-03-2018 IPR012293 RNA polymerase subunit, RPB6/omega GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708 ALX04_RS02785 33c03dd7842a9e16f1c65d3df86e9db0 70 TIGRFAM TIGR00690 rpoZ: DNA-directed RNA polymerase, omega subunit 4 59 1.3E-14 T 28-03-2018 IPR003716 DNA-directed RNA polymerase, omega subunit GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 ALX04_RS02785 33c03dd7842a9e16f1c65d3df86e9db0 70 SMART SM01409 9 62 5.1E-13 T 28-03-2018 IPR006110 RNA polymerase, subunit omega/K/RPB6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708 ALX04_RS07975 7f7fb5857b732b9f3b1fba1ce6be7572 252 SMART SM00382 36 231 9.6E-12 T 28-03-2018 IPR003593 AAA+ ATPase domain ALX04_RS07975 7f7fb5857b732b9f3b1fba1ce6be7572 252 SUPERFAMILY SSF52540 6 233 3.92E-69 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase ALX04_RS07975 7f7fb5857b732b9f3b1fba1ce6be7572 252 Gene3D G3DSA:3.40.50.300 2 246 5.6E-66 T 28-03-2018 ALX04_RS07975 7f7fb5857b732b9f3b1fba1ce6be7572 252 Pfam PF00005 ABC transporter 27 175 7.2E-35 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 ALX04_RS00570 81a56efc0c1a201f660d92d0336cae3c 147 Hamap MF_01366 50S ribosomal protein L13 [rplM]. 16 142 26.05 T 28-03-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 ALX04_RS00570 81a56efc0c1a201f660d92d0336cae3c 147 PIRSF PIRSF002181 1 146 1.3E-46 T 28-03-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 ALX04_RS00570 81a56efc0c1a201f660d92d0336cae3c 147 SUPERFAMILY SSF52161 5 144 2.09E-56 T 28-03-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 ALX04_RS00570 81a56efc0c1a201f660d92d0336cae3c 147 Gene3D G3DSA:3.90.1180.10 1 146 3.1E-58 T 28-03-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 ALX04_RS00570 81a56efc0c1a201f660d92d0336cae3c 147 Pfam PF00572 Ribosomal protein L13 15 139 1.1E-53 T 28-03-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 ALX04_RS00570 81a56efc0c1a201f660d92d0336cae3c 147 ProSitePatterns PS00783 Ribosomal protein L13 signature. 106 128 - T 28-03-2018 IPR023563 Ribosomal protein L13, conserved site GO:0003735|GO:0005840|GO:0006412 ALX04_RS00570 81a56efc0c1a201f660d92d0336cae3c 147 TIGRFAM TIGR01066 rplM_bact: ribosomal protein uL13 5 143 6.4E-59 T 28-03-2018 IPR005823 Ribosomal protein L13, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 ALX04_RS07275 40ed114e105092e9a99c6c7856e9ce38 106 Gene3D G3DSA:1.10.287.1080 1 94 1.2E-23 T 28-03-2018 ALX04_RS07275 40ed114e105092e9a99c6c7856e9ce38 106 TIGRFAM TIGR03188 histidine_hisI: phosphoribosyl-ATP diphosphatase 4 87 1.2E-33 T 28-03-2018 IPR008179 Phosphoribosyl-ATP pyrophosphohydrolase GO:0000105|GO:0004636 KEGG: 00340+3.6.1.31 ALX04_RS07275 40ed114e105092e9a99c6c7856e9ce38 106 Hamap MF_01020 Phosphoribosyl-ATP pyrophosphatase [hisE]. 1 87 21.923 T 28-03-2018 IPR008179 Phosphoribosyl-ATP pyrophosphohydrolase GO:0000105|GO:0004636 KEGG: 00340+3.6.1.31 ALX04_RS07275 40ed114e105092e9a99c6c7856e9ce38 106 Pfam PF01503 Phosphoribosyl-ATP pyrophosphohydrolase 5 90 1.4E-17 T 28-03-2018 IPR021130 Phosphoribosyl-ATP pyrophosphohydrolase-like KEGG: 00340+3.6.1.31 ALX04_RS07275 40ed114e105092e9a99c6c7856e9ce38 106 SUPERFAMILY SSF101386 4 91 9.72E-27 T 28-03-2018 ALX04_RS01315 9c936eff091b3f39afca78ec3c28c37f 504 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 3 245 9.2E-67 T 28-03-2018 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 ALX04_RS01315 9c936eff091b3f39afca78ec3c28c37f 504 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 254 448 9.3E-35 T 28-03-2018 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 ALX04_RS01315 9c936eff091b3f39afca78ec3c28c37f 504 SUPERFAMILY SSF53067 3 248 6.48E-65 T 28-03-2018 ALX04_RS01315 9c936eff091b3f39afca78ec3c28c37f 504 SUPERFAMILY SSF53067 247 496 1.41E-63 T 28-03-2018 ALX04_RS01315 9c936eff091b3f39afca78ec3c28c37f 504 Gene3D G3DSA:3.30.420.40 243 504 3.5E-65 T 28-03-2018 ALX04_RS01315 9c936eff091b3f39afca78ec3c28c37f 504 Gene3D G3DSA:3.30.420.40 1 242 9.2E-66 T 28-03-2018 ALX04_RS01315 9c936eff091b3f39afca78ec3c28c37f 504 ProSitePatterns PS00445 FGGY family of carbohydrate kinases signature 2. 362 382 - T 28-03-2018 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 ALX04_RS01315 9c936eff091b3f39afca78ec3c28c37f 504 PIRSF PIRSF000538 1 501 2.3E-138 T 28-03-2018 IPR000577 Carbohydrate kinase, FGGY GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 ALX04_RS15835 0fc633d8c22accf79a221c6a5e426c09 522 Gene3D G3DSA:1.10.3080.10 4 434 5.4E-84 T 28-03-2018 IPR014743 Chloride channel, core GO:0005216|GO:0055085 Reactome: R-HSA-2672351 ALX04_RS15835 0fc633d8c22accf79a221c6a5e426c09 522 Pfam PF02080 TrkA-C domain 445 504 1.1E-11 T 28-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 ALX04_RS15835 0fc633d8c22accf79a221c6a5e426c09 522 SUPERFAMILY SSF81340 7 431 1.24E-105 T 28-03-2018 IPR014743 Chloride channel, core GO:0005216|GO:0055085 Reactome: R-HSA-2672351 ALX04_RS15835 0fc633d8c22accf79a221c6a5e426c09 522 PRINTS PR00762 Chloride channel signature 84 101 4.3E-26 T 28-03-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 ALX04_RS15835 0fc633d8c22accf79a221c6a5e426c09 522 PRINTS PR00762 Chloride channel signature 381 400 4.3E-26 T 28-03-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 ALX04_RS15835 0fc633d8c22accf79a221c6a5e426c09 522 PRINTS PR00762 Chloride channel signature 328 348 4.3E-26 T 28-03-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 ALX04_RS15835 0fc633d8c22accf79a221c6a5e426c09 522 PRINTS PR00762 Chloride channel signature 164 183 4.3E-26 T 28-03-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 ALX04_RS15835 0fc633d8c22accf79a221c6a5e426c09 522 Gene3D G3DSA:3.30.70.1450 435 514 5.9E-13 T 28-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 ALX04_RS15835 0fc633d8c22accf79a221c6a5e426c09 522 SUPERFAMILY SSF116726 442 507 1.57E-12 T 28-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 ALX04_RS15835 0fc633d8c22accf79a221c6a5e426c09 522 Pfam PF00654 Voltage gated chloride channel 73 413 3.1E-88 T 28-03-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 ALX04_RS14090 eb38a1460d05b12f87e677844a200765 723 Pfam PF09371 Tex-like protein N-terminal domain 14 193 6.5E-66 T 28-03-2018 IPR018974 Tex-like protein, N-terminal ALX04_RS14090 eb38a1460d05b12f87e677844a200765 723 Gene3D G3DSA:1.10.3500.10 348 494 8.3E-40 T 28-03-2018 IPR023323 Tex-like domain ALX04_RS14090 eb38a1460d05b12f87e677844a200765 723 Pfam PF16921 Tex protein YqgF-like domain 320 447 5.8E-53 T 28-03-2018 IPR032639 Tex protein, YqgF-like domain ALX04_RS14090 eb38a1460d05b12f87e677844a200765 723 Gene3D G3DSA:1.10.150.310 495 628 3.0E-45 T 28-03-2018 ALX04_RS14090 eb38a1460d05b12f87e677844a200765 723 SMART SM00732 320 420 3.4E-37 T 28-03-2018 IPR006641 YqgF/RNase H-like domain GO:0006139 ALX04_RS14090 eb38a1460d05b12f87e677844a200765 723 SUPERFAMILY SSF47781 556 629 4.89E-16 T 28-03-2018 IPR010994 RuvA domain 2-like ALX04_RS14090 eb38a1460d05b12f87e677844a200765 723 SUPERFAMILY SSF50249 634 717 4.33E-23 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold ALX04_RS14090 eb38a1460d05b12f87e677844a200765 723 SUPERFAMILY SSF47781 466 552 6.56E-26 T 28-03-2018 IPR010994 RuvA domain 2-like ALX04_RS14090 eb38a1460d05b12f87e677844a200765 723 SMART SM00316 647 718 5.3E-22 T 28-03-2018 IPR022967 RNA-binding domain, S1 ALX04_RS14090 eb38a1460d05b12f87e677844a200765 723 Gene3D G3DSA:2.40.50.140 638 722 1.7E-22 T 28-03-2018 ALX04_RS14090 eb38a1460d05b12f87e677844a200765 723 Pfam PF12836 Helix-hairpin-helix motif 487 551 3.8E-26 T 28-03-2018 ALX04_RS14090 eb38a1460d05b12f87e677844a200765 723 SUPERFAMILY SSF158832 14 315 3.4E-106 T 28-03-2018 ALX04_RS14090 eb38a1460d05b12f87e677844a200765 723 Gene3D G3DSA:1.10.10.650 2 103 2.2E-31 T 28-03-2018 IPR023319 Tex-like protein, HTH domain ALX04_RS14090 eb38a1460d05b12f87e677844a200765 723 Gene3D G3DSA:1.10.3500.10 104 347 4.5E-77 T 28-03-2018 IPR023323 Tex-like domain ALX04_RS14090 eb38a1460d05b12f87e677844a200765 723 SUPERFAMILY SSF53098 316 465 9.1E-47 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 ALX04_RS14090 eb38a1460d05b12f87e677844a200765 723 Pfam PF00575 S1 RNA binding domain 647 717 3.9E-15 T 28-03-2018 IPR003029 S1 domain GO:0003676 ALX04_RS14495 ba5376c7f96578288952e8135998e852 541 PRINTS PR00298 60kDa chaperonin signature 26 52 5.5E-72 T 28-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 ALX04_RS14495 ba5376c7f96578288952e8135998e852 541 PRINTS PR00298 60kDa chaperonin signature 348 373 5.5E-72 T 28-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 ALX04_RS14495 ba5376c7f96578288952e8135998e852 541 PRINTS PR00298 60kDa chaperonin signature 396 417 5.5E-72 T 28-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 ALX04_RS14495 ba5376c7f96578288952e8135998e852 541 PRINTS PR00298 60kDa chaperonin signature 82 109 5.5E-72 T 28-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 ALX04_RS14495 ba5376c7f96578288952e8135998e852 541 PRINTS PR00298 60kDa chaperonin signature 266 289 5.5E-72 T 28-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 ALX04_RS14495 ba5376c7f96578288952e8135998e852 541 Hamap MF_00600 60 kDa chaperonin [groL]. 1 540 40.72 T 28-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 ALX04_RS14495 ba5376c7f96578288952e8135998e852 541 SUPERFAMILY SSF48592 1 228 2.35E-69 T 28-03-2018 ALX04_RS14495 ba5376c7f96578288952e8135998e852 541 TIGRFAM TIGR02348 GroEL: chaperonin GroL 2 524 1.8E-253 T 28-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 ALX04_RS14495 ba5376c7f96578288952e8135998e852 541 Gene3D G3DSA:3.50.7.10 187 370 7.9E-97 T 28-03-2018 IPR027409 GroEL-like apical domain ALX04_RS14495 ba5376c7f96578288952e8135998e852 541 SUPERFAMILY SSF52029 182 374 7.48E-84 T 28-03-2018 IPR027409 GroEL-like apical domain ALX04_RS14495 ba5376c7f96578288952e8135998e852 541 Gene3D G3DSA:1.10.560.10 1 186 6.0E-43 T 28-03-2018 IPR027413 GroEL-like equatorial domain ALX04_RS14495 ba5376c7f96578288952e8135998e852 541 Pfam PF00118 TCP-1/cpn60 chaperonin family 22 521 2.1E-105 T 28-03-2018 IPR002423 Chaperonin Cpn60/TCP-1 family GO:0005524 ALX04_RS14495 ba5376c7f96578288952e8135998e852 541 Gene3D G3DSA:1.10.560.10 371 513 3.0E-28 T 28-03-2018 IPR027413 GroEL-like equatorial domain ALX04_RS14495 ba5376c7f96578288952e8135998e852 541 ProSitePatterns PS00296 Chaperonins cpn60 signature. 403 414 - T 28-03-2018 IPR018370 Chaperonin Cpn60, conserved site GO:0005524|GO:0005737|GO:0006457 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 ALX04_RS14495 ba5376c7f96578288952e8135998e852 541 SUPERFAMILY SSF48592 370 522 3.21E-33 T 28-03-2018 ALX04_RS03790 8565b61b83a318712417b3efb25d4c45 715 Pfam PF01131 DNA topoisomerase 156 572 2.4E-128 T 28-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 ALX04_RS03790 8565b61b83a318712417b3efb25d4c45 715 SMART SM00437 271 534 7.4E-115 T 28-03-2018 IPR003602 DNA topoisomerase, type IA, DNA-binding domain GO:0003677|GO:0003916|GO:0006265 ALX04_RS03790 8565b61b83a318712417b3efb25d4c45 715 Gene3D G3DSA:3.40.50.140 30 157 3.3E-40 T 28-03-2018 ALX04_RS03790 8565b61b83a318712417b3efb25d4c45 715 TIGRFAM TIGR01051 topA_bact: DNA topoisomerase I 33 635 2.3E-242 T 28-03-2018 IPR005733 DNA topoisomerase I, bacterial-type GO:0003677|GO:0003917|GO:0006265 ALX04_RS03790 8565b61b83a318712417b3efb25d4c45 715 Hamap MF_00952 DNA topoisomerase 1 [topA]. 31 657 54.061 T 28-03-2018 IPR028612 DNA topoisomerase I, type IA GO:0003677|GO:0003916|GO:0006265 ALX04_RS03790 8565b61b83a318712417b3efb25d4c45 715 Gene3D G3DSA:1.10.460.10 163 355 8.4E-44 T 28-03-2018 ALX04_RS03790 8565b61b83a318712417b3efb25d4c45 715 Gene3D G3DSA:2.70.20.10 356 480 2.7E-36 T 28-03-2018 IPR013825 DNA topoisomerase, type IA, central region, subdomain 2 ALX04_RS03790 8565b61b83a318712417b3efb25d4c45 715 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 497 511 6.9E-35 T 28-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 ALX04_RS03790 8565b61b83a318712417b3efb25d4c45 715 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 105 118 6.9E-35 T 28-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 ALX04_RS03790 8565b61b83a318712417b3efb25d4c45 715 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 323 332 6.9E-35 T 28-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 ALX04_RS03790 8565b61b83a318712417b3efb25d4c45 715 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 400 416 6.9E-35 T 28-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 ALX04_RS03790 8565b61b83a318712417b3efb25d4c45 715 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 190 208 6.9E-35 T 28-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 ALX04_RS03790 8565b61b83a318712417b3efb25d4c45 715 SUPERFAMILY SSF56712 31 613 2.09E-192 T 28-03-2018 IPR023405 DNA topoisomerase, type IA, core domain ALX04_RS03790 8565b61b83a318712417b3efb25d4c45 715 SMART SM00436 132 220 4.0E-49 T 28-03-2018 IPR003601 DNA topoisomerase, type IA, domain 2 GO:0003677|GO:0003916|GO:0006265 ALX04_RS03790 8565b61b83a318712417b3efb25d4c45 715 Pfam PF01751 Toprim domain 33 141 3.7E-30 T 28-03-2018 IPR006171 TOPRIM domain ALX04_RS03790 8565b61b83a318712417b3efb25d4c45 715 SMART SM00493 31 131 1.4E-30 T 28-03-2018 IPR006171 TOPRIM domain ALX04_RS03790 8565b61b83a318712417b3efb25d4c45 715 SUPERFAMILY SSF57783 599 637 6.12E-13 T 28-03-2018 ALX04_RS03790 8565b61b83a318712417b3efb25d4c45 715 Gene3D G3DSA:3.30.65.10 581 637 4.8E-16 T 28-03-2018 ALX04_RS03790 8565b61b83a318712417b3efb25d4c45 715 Gene3D G3DSA:3.30.65.10 677 715 0.062 T 28-03-2018 ALX04_RS03790 8565b61b83a318712417b3efb25d4c45 715 Gene3D G3DSA:3.30.65.10 638 676 6.4E-10 T 28-03-2018 ALX04_RS03790 8565b61b83a318712417b3efb25d4c45 715 Pfam PF01396 Topoisomerase DNA binding C4 zinc finger 641 679 2.8E-13 T 28-03-2018 IPR013498 DNA topoisomerase, type IA, zn finger GO:0003677|GO:0003916|GO:0005694|GO:0006265 Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473|Reactome: R-HSA-912446 ALX04_RS03790 8565b61b83a318712417b3efb25d4c45 715 Pfam PF01396 Topoisomerase DNA binding C4 zinc finger 602 637 2.2E-13 T 28-03-2018 IPR013498 DNA topoisomerase, type IA, zn finger GO:0003677|GO:0003916|GO:0005694|GO:0006265 Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473|Reactome: R-HSA-912446 ALX04_RS07915 14391d2260982ad4f4aab6ef86ec5b8c 226 TIGRFAM TIGR01737 FGAM_synth_I: phosphoribosylformylglycinamidine synthase I 2 218 2.9E-88 T 28-03-2018 IPR010075 Phosphoribosylformylglycinamidine synthase subunit PurQ GO:0004642|GO:0005737|GO:0006189 KEGG: 00220+3.5.1.2|KEGG: 00230+6.3.5.3|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 ALX04_RS07915 14391d2260982ad4f4aab6ef86ec5b8c 226 Gene3D G3DSA:3.40.50.880 1 221 6.1E-36 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like ALX04_RS07915 14391d2260982ad4f4aab6ef86ec5b8c 226 Hamap MF_00421 Phosphoribosylformylglycinamidine synthase subunit PurQ [purQ]. 2 218 42.504 T 28-03-2018 IPR010075 Phosphoribosylformylglycinamidine synthase subunit PurQ GO:0004642|GO:0005737|GO:0006189 KEGG: 00220+3.5.1.2|KEGG: 00230+6.3.5.3|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 ALX04_RS07915 14391d2260982ad4f4aab6ef86ec5b8c 226 Pfam PF13507 CobB/CobQ-like glutamine amidotransferase domain 3 203 1.2E-42 T 28-03-2018 ALX04_RS07915 14391d2260982ad4f4aab6ef86ec5b8c 226 SMART SM01211 1 220 1.2E-122 T 28-03-2018 ALX04_RS07915 14391d2260982ad4f4aab6ef86ec5b8c 226 SUPERFAMILY SSF52317 2 217 5.14E-72 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like ALX04_RS07915 14391d2260982ad4f4aab6ef86ec5b8c 226 PIRSF PIRSF001586 1 223 2.3E-83 T 28-03-2018 IPR010075 Phosphoribosylformylglycinamidine synthase subunit PurQ GO:0004642|GO:0005737|GO:0006189 KEGG: 00220+3.5.1.2|KEGG: 00230+6.3.5.3|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 ALX04_RS05210 46d6590beeb3e012032f07e24eaad60e 395 Pfam PF00009 Elongation factor Tu GTP binding domain 10 201 1.2E-59 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 ALX04_RS05210 46d6590beeb3e012032f07e24eaad60e 395 Gene3D G3DSA:2.40.30.10 206 300 7.7E-29 T 28-03-2018 ALX04_RS05210 46d6590beeb3e012032f07e24eaad60e 395 Gene3D G3DSA:3.40.50.300 75 203 2.2E-32 T 28-03-2018 ALX04_RS05210 46d6590beeb3e012032f07e24eaad60e 395 Gene3D G3DSA:3.40.50.300 1 74 7.7E-11 T 28-03-2018 ALX04_RS05210 46d6590beeb3e012032f07e24eaad60e 395 Pfam PF03144 Elongation factor Tu domain 2 225 294 2.0E-15 T 28-03-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 ALX04_RS05210 46d6590beeb3e012032f07e24eaad60e 395 SUPERFAMILY SSF50465 303 394 1.64E-34 T 28-03-2018 IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal ALX04_RS05210 46d6590beeb3e012032f07e24eaad60e 395 Hamap MF_00118_B Elongation factor Tu [tuf]. 1 395 58.967 T 28-03-2018 IPR004541 Translation elongation factor EFTu/EF1A, bacterial/organelle GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 ALX04_RS05210 46d6590beeb3e012032f07e24eaad60e 395 TIGRFAM TIGR00485 EF-Tu: translation elongation factor Tu 1 393 3.3E-219 T 28-03-2018 IPR004541 Translation elongation factor EFTu/EF1A, bacterial/organelle GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 ALX04_RS05210 46d6590beeb3e012032f07e24eaad60e 395 SUPERFAMILY SSF50447 203 300 2.55E-29 T 28-03-2018 IPR009000 Translation protein, beta-barrel domain ALX04_RS05210 46d6590beeb3e012032f07e24eaad60e 395 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 51 66 - T 28-03-2018 IPR031157 Tr-type G domain, conserved site ALX04_RS05210 46d6590beeb3e012032f07e24eaad60e 395 Gene3D G3DSA:2.40.30.10 301 393 6.6E-30 T 28-03-2018 ALX04_RS05210 46d6590beeb3e012032f07e24eaad60e 395 PRINTS PR00315 GTP-binding elongation factor signature 94 105 4.1E-25 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 ALX04_RS05210 46d6590beeb3e012032f07e24eaad60e 395 PRINTS PR00315 GTP-binding elongation factor signature 78 88 4.1E-25 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 ALX04_RS05210 46d6590beeb3e012032f07e24eaad60e 395 PRINTS PR00315 GTP-binding elongation factor signature 58 66 4.1E-25 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 ALX04_RS05210 46d6590beeb3e012032f07e24eaad60e 395 PRINTS PR00315 GTP-binding elongation factor signature 131 140 4.1E-25 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 ALX04_RS05210 46d6590beeb3e012032f07e24eaad60e 395 PRINTS PR00315 GTP-binding elongation factor signature 14 27 4.1E-25 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 ALX04_RS05210 46d6590beeb3e012032f07e24eaad60e 395 Pfam PF03143 Elongation factor Tu C-terminal domain 299 393 6.2E-32 T 28-03-2018 IPR004160 Translation elongation factor EFTu/EF1A, C-terminal ALX04_RS05210 46d6590beeb3e012032f07e24eaad60e 395 SUPERFAMILY SSF52540 9 226 1.76E-62 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase ALX04_RS05210 46d6590beeb3e012032f07e24eaad60e 395 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 13 146 1.7E-16 T 28-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 ALX04_RS11750 277fc9d984dd6fe9a6620d806ff5fdc5 191 SUPERFAMILY SSF46689 2 72 1.1E-13 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 ALX04_RS11750 277fc9d984dd6fe9a6620d806ff5fdc5 191 Pfam PF00440 Bacterial regulatory proteins, tetR family 12 58 1.0E-11 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 ALX04_RS11750 277fc9d984dd6fe9a6620d806ff5fdc5 191 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 12 25 2.2E-7 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 ALX04_RS11750 277fc9d984dd6fe9a6620d806ff5fdc5 191 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 33 56 2.2E-7 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 ALX04_RS11750 277fc9d984dd6fe9a6620d806ff5fdc5 191 Gene3D G3DSA:1.10.10.60 47 143 1.5E-7 T 28-03-2018 ALX04_RS11750 277fc9d984dd6fe9a6620d806ff5fdc5 191 Gene3D G3DSA:1.10.10.60 7 46 1.3E-12 T 28-03-2018 ALX04_RS04510 ad2caf0b6932ff660605a31b9ceb9567 391 Gene3D G3DSA:3.40.710.10 32 388 2.8E-56 T 28-03-2018 ALX04_RS04510 ad2caf0b6932ff660605a31b9ceb9567 391 Pfam PF00144 Beta-lactamase 86 368 2.6E-41 T 28-03-2018 IPR001466 Beta-lactamase-related ALX04_RS04510 ad2caf0b6932ff660605a31b9ceb9567 391 SUPERFAMILY SSF56601 70 379 5.86E-63 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like ALX04_RS04600 8a718dabad768a1e3b6fc1e5a4ae2e1a 405 TIGRFAM TIGR01953 NusA: transcription termination factor NusA 5 342 8.2E-132 T 28-03-2018 IPR010213 Transcription termination factor NusA GO:0003723 ALX04_RS04600 8a718dabad768a1e3b6fc1e5a4ae2e1a 405 Gene3D G3DSA:2.40.50.140 136 197 1.7E-13 T 28-03-2018 ALX04_RS04600 8a718dabad768a1e3b6fc1e5a4ae2e1a 405 Pfam PF13184 NusA-like KH domain 229 296 1.6E-30 T 28-03-2018 IPR025249 KH domain, NusA-like GO:0003723 ALX04_RS04600 8a718dabad768a1e3b6fc1e5a4ae2e1a 405 Pfam PF08529 NusA N-terminal domain 4 123 9.3E-43 T 28-03-2018 IPR013735 Transcription factor NusA, N-terminal GO:0003700|GO:0031554 ALX04_RS04600 8a718dabad768a1e3b6fc1e5a4ae2e1a 405 SMART SM00322 229 292 5.8 T 28-03-2018 IPR004087 K Homology domain GO:0003676 ALX04_RS04600 8a718dabad768a1e3b6fc1e5a4ae2e1a 405 SMART SM00322 301 367 0.082 T 28-03-2018 IPR004087 K Homology domain GO:0003676 ALX04_RS04600 8a718dabad768a1e3b6fc1e5a4ae2e1a 405 Gene3D G3DSA:3.30.300.20 198 272 1.1E-35 T 28-03-2018 IPR015946 K homology domain-like, alpha/beta ALX04_RS04600 8a718dabad768a1e3b6fc1e5a4ae2e1a 405 SMART SM00316 133 199 5.0E-7 T 28-03-2018 IPR022967 RNA-binding domain, S1 ALX04_RS04600 8a718dabad768a1e3b6fc1e5a4ae2e1a 405 Hamap MF_00945_B Transcription termination/antitermination protein NusA [nusA]. 2 401 29.89 T 28-03-2018 IPR030842 Transcription termination/antitermination protein NusA, bacterial GO:0006353|GO:0031564 ALX04_RS04600 8a718dabad768a1e3b6fc1e5a4ae2e1a 405 Gene3D G3DSA:3.30.1480.10 1 129 1.7E-50 T 28-03-2018 IPR013735 Transcription factor NusA, N-terminal GO:0003700|GO:0031554 ALX04_RS04600 8a718dabad768a1e3b6fc1e5a4ae2e1a 405 SUPERFAMILY SSF50249 132 198 7.1E-18 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold ALX04_RS04600 8a718dabad768a1e3b6fc1e5a4ae2e1a 405 SUPERFAMILY SSF54814 199 277 1.11E-30 T 28-03-2018 IPR009019 K homology domain, prokaryotic type GO:0003723 ALX04_RS04600 8a718dabad768a1e3b6fc1e5a4ae2e1a 405 Gene3D G3DSA:3.30.300.20 273 342 3.0E-14 T 28-03-2018 IPR015946 K homology domain-like, alpha/beta ALX04_RS04600 8a718dabad768a1e3b6fc1e5a4ae2e1a 405 Pfam PF00575 S1 RNA binding domain 134 193 1.2E-6 T 28-03-2018 IPR003029 S1 domain GO:0003676 ALX04_RS04600 8a718dabad768a1e3b6fc1e5a4ae2e1a 405 SUPERFAMILY SSF69705 1 126 5.23E-44 T 28-03-2018 IPR013735 Transcription factor NusA, N-terminal GO:0003700|GO:0031554 ALX04_RS04600 8a718dabad768a1e3b6fc1e5a4ae2e1a 405 SUPERFAMILY SSF54814 278 342 1.77E-15 T 28-03-2018 IPR009019 K homology domain, prokaryotic type GO:0003723 ALX04_RS00680 eb31c05d53edb7d4a2784450cf2b638a 386 Gene3D G3DSA:3.40.50.10380 3 157 1.0E-25 T 28-03-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 ALX04_RS00680 eb31c05d53edb7d4a2784450cf2b638a 386 SMART SM01274 15 148 2.9E-53 T 28-03-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 ALX04_RS00680 eb31c05d53edb7d4a2784450cf2b638a 386 Gene3D G3DSA:3.40.50.720 158 386 4.1E-55 T 28-03-2018 ALX04_RS00680 eb31c05d53edb7d4a2784450cf2b638a 386 Pfam PF00390 Malic enzyme, N-terminal domain 29 110 5.4E-14 T 28-03-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 ALX04_RS00680 eb31c05d53edb7d4a2784450cf2b638a 386 SUPERFAMILY SSF51735 160 384 1.97E-55 T 28-03-2018 IPR016040 NAD(P)-binding domain ALX04_RS00680 eb31c05d53edb7d4a2784450cf2b638a 386 PRINTS PR00072 Malic enzyme signature 156 172 4.8E-8 T 28-03-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 ALX04_RS00680 eb31c05d53edb7d4a2784450cf2b638a 386 PRINTS PR00072 Malic enzyme signature 77 99 4.8E-8 T 28-03-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 ALX04_RS00680 eb31c05d53edb7d4a2784450cf2b638a 386 PRINTS PR00072 Malic enzyme signature 277 293 4.8E-8 T 28-03-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 ALX04_RS00680 eb31c05d53edb7d4a2784450cf2b638a 386 SUPERFAMILY SSF53223 6 158 3.88E-45 T 28-03-2018 ALX04_RS00680 eb31c05d53edb7d4a2784450cf2b638a 386 PIRSF PIRSF000106 34 386 1.2E-66 T 28-03-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 ALX04_RS00680 eb31c05d53edb7d4a2784450cf2b638a 386 Pfam PF03949 Malic enzyme, NAD binding domain 161 382 1.6E-18 T 28-03-2018 IPR012302 Malic enzyme, NAD-binding GO:0051287 ALX04_RS00680 eb31c05d53edb7d4a2784450cf2b638a 386 SMART SM00919 160 383 1.6E-81 T 28-03-2018 IPR012302 Malic enzyme, NAD-binding GO:0051287 ALX04_RS13770 f81e682cfe4babcfe474b8fa4961db0e 402 ProDom PD004193 ACETYLTRANSFERASE ORNITHINE ARGININE BIOSYNTHESIS ARGJ GLUTAMATE N-ACETYLTRANSFERASE TRANSFERASE ACYLTRANSFERASE BIFUNCTIONAL 33 402 0.0 T 28-03-2018 ALX04_RS13770 f81e682cfe4babcfe474b8fa4961db0e 402 TIGRFAM TIGR00120 ArgJ: glutamate N-acetyltransferase/amino-acid acetyltransferase 17 402 2.5E-134 T 28-03-2018 IPR002813 Arginine biosynthesis protein ArgJ GO:0004358|GO:0006526 KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 ALX04_RS13770 f81e682cfe4babcfe474b8fa4961db0e 402 SUPERFAMILY SSF56266 16 398 4.32E-126 T 28-03-2018 IPR016117 ArgJ-like domain KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 ALX04_RS13770 f81e682cfe4babcfe474b8fa4961db0e 402 Gene3D G3DSA:3.60.70.12 10 275 1.5E-91 T 28-03-2018 IPR016117 ArgJ-like domain KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 ALX04_RS13770 f81e682cfe4babcfe474b8fa4961db0e 402 Hamap MF_01106 Arginine biosynthesis bifunctional protein ArgJ [argJ]. 1 402 130.005 T 28-03-2018 IPR002813 Arginine biosynthesis protein ArgJ GO:0004358|GO:0006526 KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 ALX04_RS13770 f81e682cfe4babcfe474b8fa4961db0e 402 Pfam PF01960 ArgJ family 23 402 5.5E-137 T 28-03-2018 IPR002813 Arginine biosynthesis protein ArgJ GO:0004358|GO:0006526 KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 ALX04_RS08265 b09223e14d5ad02c5e2b378b906b0d39 299 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 7 63 9.3E-13 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 ALX04_RS08265 b09223e14d5ad02c5e2b378b906b0d39 299 Gene3D G3DSA:3.40.190.10 91 195 0.0015 T 28-03-2018 ALX04_RS08265 b09223e14d5ad02c5e2b378b906b0d39 299 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 30 40 8.9E-6 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 ALX04_RS08265 b09223e14d5ad02c5e2b378b906b0d39 299 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 19 30 8.9E-6 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 ALX04_RS08265 b09223e14d5ad02c5e2b378b906b0d39 299 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 40 51 8.9E-6 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 ALX04_RS08265 b09223e14d5ad02c5e2b378b906b0d39 299 SUPERFAMILY SSF46785 6 88 4.05E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS08265 b09223e14d5ad02c5e2b378b906b0d39 299 Gene3D G3DSA:1.10.10.10 5 84 1.3E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS02720 c3ecfe8b30a03643df63e5dc58f900a9 286 ProSitePatterns PS00767 Tetrahydrofolate dehydrogenase/cyclohydrolase signature 2. 260 268 - T 28-03-2018 IPR020867 Tetrahydrofolate dehydrogenase/cyclohydrolase, conserved site GO:0003824|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 ALX04_RS02720 c3ecfe8b30a03643df63e5dc58f900a9 286 Pfam PF00763 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain 4 119 2.0E-37 T 28-03-2018 IPR020630 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 ALX04_RS02720 c3ecfe8b30a03643df63e5dc58f900a9 286 Gene3D G3DSA:3.40.50.720 139 264 5.7E-37 T 28-03-2018 ALX04_RS02720 c3ecfe8b30a03643df63e5dc58f900a9 286 SUPERFAMILY SSF53223 2 120 9.3E-38 T 28-03-2018 ALX04_RS02720 c3ecfe8b30a03643df63e5dc58f900a9 286 Hamap MF_01576 Bifunctional protein FolD [folD]. 2 283 36.002 T 28-03-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 ALX04_RS02720 c3ecfe8b30a03643df63e5dc58f900a9 286 SUPERFAMILY SSF51735 121 280 2.71E-48 T 28-03-2018 IPR016040 NAD(P)-binding domain ALX04_RS02720 c3ecfe8b30a03643df63e5dc58f900a9 286 Pfam PF02882 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 122 281 1.1E-63 T 28-03-2018 IPR020631 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain GO:0004488 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 ALX04_RS02720 c3ecfe8b30a03643df63e5dc58f900a9 286 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 73 100 2.6E-78 T 28-03-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 ALX04_RS02720 c3ecfe8b30a03643df63e5dc58f900a9 286 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 108 129 2.6E-78 T 28-03-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 ALX04_RS02720 c3ecfe8b30a03643df63e5dc58f900a9 286 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 155 175 2.6E-78 T 28-03-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 ALX04_RS02720 c3ecfe8b30a03643df63e5dc58f900a9 286 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 32 54 2.6E-78 T 28-03-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 ALX04_RS02720 c3ecfe8b30a03643df63e5dc58f900a9 286 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 204 233 2.6E-78 T 28-03-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 ALX04_RS02720 c3ecfe8b30a03643df63e5dc58f900a9 286 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 239 255 2.6E-78 T 28-03-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 ALX04_RS02720 c3ecfe8b30a03643df63e5dc58f900a9 286 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 256 274 2.6E-78 T 28-03-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 ALX04_RS02720 c3ecfe8b30a03643df63e5dc58f900a9 286 Gene3D G3DSA:3.40.50.10860 10 138 1.2E-43 T 28-03-2018 ALX04_RS06420 f28ec154753d6dad5de1267a4d53a66e 506 SUPERFAMILY SSF52540 95 370 3.63E-96 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase ALX04_RS06420 f28ec154753d6dad5de1267a4d53a66e 506 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 355 364 - T 28-03-2018 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 ALX04_RS06420 f28ec154753d6dad5de1267a4d53a66e 506 Pfam PF02874 ATP synthase alpha/beta family, beta-barrel domain 25 92 2.4E-21 T 28-03-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 ALX04_RS06420 f28ec154753d6dad5de1267a4d53a66e 506 Pfam PF00306 ATP synthase alpha/beta chain, C terminal domain 371 496 5.0E-47 T 28-03-2018 IPR000793 ATP synthase, alpha subunit, C-terminal GO:0015986 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 ALX04_RS06420 f28ec154753d6dad5de1267a4d53a66e 506 Gene3D G3DSA:3.40.50.300 83 364 5.0E-117 T 28-03-2018 ALX04_RS06420 f28ec154753d6dad5de1267a4d53a66e 506 Gene3D G3DSA:1.20.150.20 373 498 2.2E-49 T 28-03-2018 ALX04_RS06420 f28ec154753d6dad5de1267a4d53a66e 506 Hamap MF_01346 ATP synthase subunit alpha [atpA]. 1 499 49.661 T 28-03-2018 IPR005294 ATP synthase, F1 complex, alpha subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 ALX04_RS06420 f28ec154753d6dad5de1267a4d53a66e 506 SUPERFAMILY SSF50615 10 94 5.69E-29 T 28-03-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 ALX04_RS06420 f28ec154753d6dad5de1267a4d53a66e 506 Gene3D G3DSA:2.40.30.20 3 82 4.1E-35 T 28-03-2018 IPR023366 ATP synthase subunit alpha-like domain KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 ALX04_RS06420 f28ec154753d6dad5de1267a4d53a66e 506 SUPERFAMILY SSF47917 372 499 1.46E-46 T 28-03-2018 ALX04_RS06420 f28ec154753d6dad5de1267a4d53a66e 506 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 149 364 1.5E-69 T 28-03-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 ALX04_RS06420 f28ec154753d6dad5de1267a4d53a66e 506 PIRSF PIRSF039088 1 501 4.0E-241 T 28-03-2018 IPR005294 ATP synthase, F1 complex, alpha subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 ALX04_RS06420 f28ec154753d6dad5de1267a4d53a66e 506 TIGRFAM TIGR00962 atpA: ATP synthase F1, alpha subunit 3 498 3.1E-247 T 28-03-2018 IPR005294 ATP synthase, F1 complex, alpha subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 ALX04_RS06390 281814f0b5958fe0151cfe1a800764f6 333 Gene3D G3DSA:3.30.420.40 1 152 2.8E-35 T 28-03-2018 ALX04_RS06390 281814f0b5958fe0151cfe1a800764f6 333 SUPERFAMILY SSF53067 141 326 2.32E-45 T 28-03-2018 ALX04_RS06390 281814f0b5958fe0151cfe1a800764f6 333 TIGRFAM TIGR00904 mreB: cell shape determining protein, MreB/Mrl family 3 328 7.5E-128 T 28-03-2018 IPR004753 Cell shape determining protein MreB GO:0000902 ALX04_RS06390 281814f0b5958fe0151cfe1a800764f6 333 Gene3D G3DSA:3.30.420.40 240 310 3.1E-8 T 28-03-2018 ALX04_RS06390 281814f0b5958fe0151cfe1a800764f6 333 Gene3D G3DSA:3.30.420.40 153 239 2.2E-25 T 28-03-2018 ALX04_RS06390 281814f0b5958fe0151cfe1a800764f6 333 SUPERFAMILY SSF53067 3 139 3.3E-37 T 28-03-2018 ALX04_RS06390 281814f0b5958fe0151cfe1a800764f6 333 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 60 83 7.9E-51 T 28-03-2018 IPR004753 Cell shape determining protein MreB GO:0000902 ALX04_RS06390 281814f0b5958fe0151cfe1a800764f6 333 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 178 198 7.9E-51 T 28-03-2018 IPR004753 Cell shape determining protein MreB GO:0000902 ALX04_RS06390 281814f0b5958fe0151cfe1a800764f6 333 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 123 142 7.9E-51 T 28-03-2018 IPR004753 Cell shape determining protein MreB GO:0000902 ALX04_RS06390 281814f0b5958fe0151cfe1a800764f6 333 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 40 58 7.9E-51 T 28-03-2018 IPR004753 Cell shape determining protein MreB GO:0000902 ALX04_RS06390 281814f0b5958fe0151cfe1a800764f6 333 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 293 319 7.9E-51 T 28-03-2018 IPR004753 Cell shape determining protein MreB GO:0000902 ALX04_RS06390 281814f0b5958fe0151cfe1a800764f6 333 Pfam PF06723 MreB/Mbl protein 4 328 9.8E-139 T 28-03-2018 IPR004753 Cell shape determining protein MreB GO:0000902 ALX04_RS01305 efcdf9ffd95a94356ae155e7ec17ed5d 132 Gene3D G3DSA:3.40.50.620 1 126 1.9E-29 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold ALX04_RS01305 efcdf9ffd95a94356ae155e7ec17ed5d 132 TIGRFAM TIGR01518 g3p_cytidyltrns: glycerol-3-phosphate cytidylyltransferase 4 126 1.4E-60 T 28-03-2018 IPR006409 Glycerol-3-phosphate cytidylyltransferase GO:0005737|GO:0019350|GO:0046872|GO:0047348 ALX04_RS01305 efcdf9ffd95a94356ae155e7ec17ed5d 132 Pfam PF01467 Cytidylyltransferase-like 5 123 3.7E-20 T 28-03-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 ALX04_RS01305 efcdf9ffd95a94356ae155e7ec17ed5d 132 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 4 68 1.1E-20 T 28-03-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 ALX04_RS01305 efcdf9ffd95a94356ae155e7ec17ed5d 132 SUPERFAMILY SSF52374 2 124 5.63E-34 T 28-03-2018 ALX04_RS12865 aa00bf0f2f32bbd8636149cdc0d5e93b 187 SUPERFAMILY SSF48150 1 183 5.49E-75 T 28-03-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 ALX04_RS12865 aa00bf0f2f32bbd8636149cdc0d5e93b 187 Gene3D G3DSA:1.10.340.30 1 181 8.7E-76 T 28-03-2018 ALX04_RS12865 aa00bf0f2f32bbd8636149cdc0d5e93b 187 Pfam PF03352 Methyladenine glycosylase 6 180 4.6E-72 T 28-03-2018 IPR005019 Methyladenine glycosylase GO:0006284|GO:0008725 ALX04_RS15250 c9574513d013c5b6000995e578146af2 218 Gene3D G3DSA:3.40.50.1240 2 218 2.4E-47 T 28-03-2018 IPR029033 Histidine phosphatase superfamily ALX04_RS15250 c9574513d013c5b6000995e578146af2 218 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 6 210 2.0E-34 T 28-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 ALX04_RS15250 c9574513d013c5b6000995e578146af2 218 SMART SM00855 5 178 6.6E-21 T 28-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 ALX04_RS15250 c9574513d013c5b6000995e578146af2 218 PIRSF PIRSF000709 2 87 0.0012 T 28-03-2018 ALX04_RS15250 c9574513d013c5b6000995e578146af2 218 SUPERFAMILY SSF53254 1 218 2.62E-54 T 28-03-2018 IPR029033 Histidine phosphatase superfamily ALX04_RS03290 925e69af892c017ce3efe80437a193fa 748 SUPERFAMILY SSF48208 269 744 8.42E-136 T 28-03-2018 IPR008928 Six-hairpin glycosidase-like GO:0003824 ALX04_RS03290 925e69af892c017ce3efe80437a193fa 748 Pfam PF03633 Glycosyl hydrolase family 65, C-terminal domain 695 745 3.4E-16 T 28-03-2018 IPR005194 Glycoside hydrolase family 65, C-terminal ALX04_RS03290 925e69af892c017ce3efe80437a193fa 748 Gene3D G3DSA:2.70.98.40 1 264 2.4E-62 T 28-03-2018 IPR005196 Glycoside hydrolase, family 65, N-terminal GO:0003824|GO:0005975 ALX04_RS03290 925e69af892c017ce3efe80437a193fa 748 PIRSF PIRSF036289 1 748 2.7E-278 T 28-03-2018 IPR017045 Maltose phosphorylase/glycosyl hydrolase/vacuolar acid trehalase ALX04_RS03290 925e69af892c017ce3efe80437a193fa 748 SUPERFAMILY SSF74650 1 263 9.73E-81 T 28-03-2018 IPR011013 Galactose mutarotase-like domain GO:0003824|GO:0005975|GO:0030246 ALX04_RS03290 925e69af892c017ce3efe80437a193fa 748 Gene3D G3DSA:1.50.10.10 312 676 1.7E-112 T 28-03-2018 ALX04_RS03290 925e69af892c017ce3efe80437a193fa 748 Pfam PF03636 Glycosyl hydrolase family 65, N-terminal domain 14 261 1.1E-54 T 28-03-2018 IPR005196 Glycoside hydrolase, family 65, N-terminal GO:0003824|GO:0005975 ALX04_RS03290 925e69af892c017ce3efe80437a193fa 748 Pfam PF03632 Glycosyl hydrolase family 65 central catalytic domain 318 691 2.5E-144 T 28-03-2018 IPR005195 Glycoside hydrolase, family 65, central catalytic GO:0003824|GO:0005975 ALX04_RS03290 925e69af892c017ce3efe80437a193fa 748 Gene3D G3DSA:2.60.420.10 677 748 1.0E-21 T 28-03-2018 ALX04_RS09030 f4fd6c75f988c35679bc31ab23a2a3b9 295 Pfam PF00480 ROK family 6 283 1.9E-48 T 28-03-2018 IPR000600 ROK family Reactome: R-HSA-4085001 ALX04_RS09030 f4fd6c75f988c35679bc31ab23a2a3b9 295 Gene3D G3DSA:3.30.420.40 115 293 1.7E-41 T 28-03-2018 ALX04_RS09030 f4fd6c75f988c35679bc31ab23a2a3b9 295 Gene3D G3DSA:3.30.420.40 3 114 4.8E-26 T 28-03-2018 ALX04_RS09030 f4fd6c75f988c35679bc31ab23a2a3b9 295 SUPERFAMILY SSF53067 6 288 9.86E-54 T 28-03-2018 ALX04_RS08935 63465d4fd1f2214cc86dcfbcd0d7af58 300 Gene3D G3DSA:1.10.10.10 1 84 6.0E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS08935 63465d4fd1f2214cc86dcfbcd0d7af58 300 SUPERFAMILY SSF46785 1 84 7.19E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS08935 63465d4fd1f2214cc86dcfbcd0d7af58 300 Gene3D G3DSA:3.40.190.10 92 181 2.4E-17 T 28-03-2018 ALX04_RS08935 63465d4fd1f2214cc86dcfbcd0d7af58 300 Gene3D G3DSA:3.40.190.10 182 269 9.5E-16 T 28-03-2018 ALX04_RS08935 63465d4fd1f2214cc86dcfbcd0d7af58 300 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 63 2.7E-16 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 ALX04_RS08935 63465d4fd1f2214cc86dcfbcd0d7af58 300 Pfam PF03466 LysR substrate binding domain 94 290 1.3E-29 T 28-03-2018 IPR005119 LysR, substrate-binding ALX04_RS08935 63465d4fd1f2214cc86dcfbcd0d7af58 300 SUPERFAMILY SSF53850 94 295 3.8E-27 T 28-03-2018 ALX04_RS03090 8faeafa7f37590d18842e4e2dda22622 295 Gene3D G3DSA:3.40.190.10 88 177 2.7E-15 T 28-03-2018 ALX04_RS03090 8faeafa7f37590d18842e4e2dda22622 295 Pfam PF03466 LysR substrate binding domain 90 287 3.1E-24 T 28-03-2018 IPR005119 LysR, substrate-binding ALX04_RS03090 8faeafa7f37590d18842e4e2dda22622 295 Gene3D G3DSA:1.10.10.10 1 83 1.7E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS03090 8faeafa7f37590d18842e4e2dda22622 295 Gene3D G3DSA:3.40.190.10 178 265 7.3E-12 T 28-03-2018 ALX04_RS03090 8faeafa7f37590d18842e4e2dda22622 295 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 62 2.1E-15 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 ALX04_RS03090 8faeafa7f37590d18842e4e2dda22622 295 SUPERFAMILY SSF46785 1 83 3.49E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS03090 8faeafa7f37590d18842e4e2dda22622 295 SUPERFAMILY SSF53850 92 292 8.58E-23 T 28-03-2018 ALX04_RS06065 423e3ede76ccc03f3e7115b03a91ae88 1022 Pfam PF09586 Bacterial membrane protein YfhO 16 997 7.8E-153 T 28-03-2018 IPR018580 Uncharacterised protein family YfhO ALX04_RS07220 7c2cacc1cd925645f14bd5437d109a1b 428 TIGRFAM TIGR01326 OAH_OAS_sulfhy: O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase 10 426 1.4E-191 T 28-03-2018 IPR006235 O-acetylhomoserine/O-acetylserine sulfhydrylase GO:0006520|GO:0016765 ALX04_RS07220 7c2cacc1cd925645f14bd5437d109a1b 428 SUPERFAMILY SSF53383 9 426 2.89E-117 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase ALX04_RS07220 7c2cacc1cd925645f14bd5437d109a1b 428 PIRSF PIRSF001434 1 428 1.2E-124 T 28-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 ALX04_RS07220 7c2cacc1cd925645f14bd5437d109a1b 428 Gene3D G3DSA:3.90.1150.10 294 428 1.8E-47 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 ALX04_RS07220 7c2cacc1cd925645f14bd5437d109a1b 428 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 12 425 8.8E-140 T 28-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 ALX04_RS07220 7c2cacc1cd925645f14bd5437d109a1b 428 Gene3D G3DSA:3.40.640.10 9 292 9.8E-59 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 ALX04_RS07220 7c2cacc1cd925645f14bd5437d109a1b 428 ProSitePatterns PS00868 Cys/Met metabolism enzymes pyridoxal-phosphate attachment site. 203 217 - T 28-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 ALX04_RS07380 33228be2fdf5b6d0427350b00e9e1f67 724 Gene3D G3DSA:2.60.40.1280 24 153 3.3E-20 T 28-03-2018 IPR011252 Fibrogen-binding domain 1 GO:0005618|GO:0007155 ALX04_RS07380 33228be2fdf5b6d0427350b00e9e1f67 724 SUPERFAMILY SSF49478 401 464 1.92E-6 T 28-03-2018 ALX04_RS07380 33228be2fdf5b6d0427350b00e9e1f67 724 SUPERFAMILY SSF49401 168 272 3.23E-10 T 28-03-2018 IPR008966 Adhesion domain ALX04_RS07380 33228be2fdf5b6d0427350b00e9e1f67 724 SUPERFAMILY SSF49401 41 153 2.24E-20 T 28-03-2018 IPR008966 Adhesion domain ALX04_RS07380 33228be2fdf5b6d0427350b00e9e1f67 724 Gene3D G3DSA:2.60.40.810 288 380 1.1E-21 T 28-03-2018 ALX04_RS07380 33228be2fdf5b6d0427350b00e9e1f67 724 Gene3D G3DSA:2.60.40.810 381 501 7.0E-26 T 28-03-2018 ALX04_RS07380 33228be2fdf5b6d0427350b00e9e1f67 724 Gene3D G3DSA:2.60.40.740 154 283 2.5E-13 T 28-03-2018 ALX04_RS07380 33228be2fdf5b6d0427350b00e9e1f67 724 Pfam PF05737 Collagen binding domain 172 275 1.4E-5 T 28-03-2018 IPR008456 Collagen binding domain GO:0005518 ALX04_RS07380 33228be2fdf5b6d0427350b00e9e1f67 724 SUPERFAMILY SSF49478 302 366 1.37E-7 T 28-03-2018 ALX04_RS07380 33228be2fdf5b6d0427350b00e9e1f67 724 TIGRFAM TIGR01167 LPXTG_anchor: LPXTG cell wall anchor domain 690 723 6.9E-4 T 28-03-2018 ALX04_RS12350 b1d7e9aa4b1e3526e7d6c2c83bb60701 948 SUPERFAMILY SSF49299 689 798 4.71E-20 T 28-03-2018 IPR000601 PKD domain ALX04_RS12350 b1d7e9aa4b1e3526e7d6c2c83bb60701 948 Gene3D G3DSA:3.20.20.80 43 431 1.8E-72 T 28-03-2018 ALX04_RS12350 b1d7e9aa4b1e3526e7d6c2c83bb60701 948 Gene3D G3DSA:2.60.40.10 723 795 5.7E-19 T 28-03-2018 IPR013783 Immunoglobulin-like fold ALX04_RS12350 b1d7e9aa4b1e3526e7d6c2c83bb60701 948 Gene3D G3DSA:2.60.120.260 796 948 5.0E-29 T 28-03-2018 IPR008979 Galactose-binding domain-like ALX04_RS12350 b1d7e9aa4b1e3526e7d6c2c83bb60701 948 Pfam PF00801 PKD domain 725 786 4.5E-13 T 28-03-2018 IPR000601 PKD domain ALX04_RS12350 b1d7e9aa4b1e3526e7d6c2c83bb60701 948 SUPERFAMILY SSF49785 799 942 7.02E-26 T 28-03-2018 IPR008979 Galactose-binding domain-like ALX04_RS12350 b1d7e9aa4b1e3526e7d6c2c83bb60701 948 Pfam PF03644 Glycosyl hydrolase family 85 117 450 2.4E-87 T 28-03-2018 IPR005201 Glycoside hydrolase, family 85 GO:0005737|GO:0033925 KEGG: 00511+3.2.1.96|Reactome: R-HSA-532668 ALX04_RS12350 b1d7e9aa4b1e3526e7d6c2c83bb60701 948 Gene3D G3DSA:2.60.40.10 613 722 1.9E-5 T 28-03-2018 IPR013783 Immunoglobulin-like fold ALX04_RS12350 b1d7e9aa4b1e3526e7d6c2c83bb60701 948 Gene3D G3DSA:2.60.120.260 432 611 1.6E-43 T 28-03-2018 IPR008979 Galactose-binding domain-like ALX04_RS12350 b1d7e9aa4b1e3526e7d6c2c83bb60701 948 SMART SM00089 719 801 7.9E-17 T 28-03-2018 IPR022409 PKD/Chitinase domain ALX04_RS12350 b1d7e9aa4b1e3526e7d6c2c83bb60701 948 SMART SM00231 804 943 0.0053 T 28-03-2018 IPR000421 Coagulation factor 5/8 C-terminal domain ALX04_RS12350 b1d7e9aa4b1e3526e7d6c2c83bb60701 948 Pfam PF00754 F5/8 type C domain 816 927 4.5E-20 T 28-03-2018 IPR000421 Coagulation factor 5/8 C-terminal domain ALX04_RS09315 2ba9be4dddde03c3d350e7e9bd4d7a2f 212 SUPERFAMILY SSF51735 1 194 5.51E-27 T 28-03-2018 IPR016040 NAD(P)-binding domain ALX04_RS09315 2ba9be4dddde03c3d350e7e9bd4d7a2f 212 Gene3D G3DSA:3.40.50.720 1 207 8.9E-18 T 28-03-2018 ALX04_RS09315 2ba9be4dddde03c3d350e7e9bd4d7a2f 212 Pfam PF13460 NAD(P)H-binding 8 189 1.1E-45 T 28-03-2018 IPR016040 NAD(P)-binding domain ALX04_RS03310 107f2eaaad41ef5c33c6ed9056420333 325 SUPERFAMILY SSF54211 2 167 3.11E-40 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold ALX04_RS03310 107f2eaaad41ef5c33c6ed9056420333 325 Gene3D G3DSA:3.30.70.890 174 315 7.6E-42 T 28-03-2018 IPR013750 GHMP kinase, C-terminal domain ALX04_RS03310 107f2eaaad41ef5c33c6ed9056420333 325 PIRSF PIRSF015950 1 325 9.2E-128 T 28-03-2018 IPR005935 Diphosphomevalonate/phosphomevalonate decarboxylase GO:0008299|GO:0016831 KEGG: 00900+4.1.1.33|MetaCyc: PWY-7391|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-2426168|Reactome: R-HSA-446199 ALX04_RS03310 107f2eaaad41ef5c33c6ed9056420333 325 TIGRFAM TIGR01240 mevDPdecarb: diphosphomevalonate decarboxylase 5 306 1.5E-104 T 28-03-2018 IPR029765 Diphosphomevalonate decarboxylase GO:0004163|GO:0005829|GO:0019287 KEGG: 00900+4.1.1.33|MetaCyc: PWY-7391|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-2426168|Reactome: R-HSA-446199 ALX04_RS03310 107f2eaaad41ef5c33c6ed9056420333 325 Gene3D G3DSA:3.30.230.10 1 173 1.9E-60 T 28-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup ALX04_RS03310 107f2eaaad41ef5c33c6ed9056420333 325 Pfam PF00288 GHMP kinases N terminal domain 91 147 9.9E-6 T 28-03-2018 IPR006204 GHMP kinase N-terminal domain GO:0005524 ALX04_RS03310 107f2eaaad41ef5c33c6ed9056420333 325 SUPERFAMILY SSF55060 174 324 7.91E-44 T 28-03-2018 IPR013750 GHMP kinase, C-terminal domain ALX04_RS10935 629049600952be7adcf8e2a97dfa143f 216 SUPERFAMILY SSF81338 1 212 2.75E-54 T 28-03-2018 IPR023271 Aquaporin-like Reactome: R-HSA-432047 ALX04_RS10935 629049600952be7adcf8e2a97dfa143f 216 Pfam PF00230 Major intrinsic protein 2 207 9.2E-47 T 28-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 ALX04_RS10935 629049600952be7adcf8e2a97dfa143f 216 Gene3D G3DSA:1.20.1080.10 1 216 9.6E-57 T 28-03-2018 IPR023271 Aquaporin-like Reactome: R-HSA-432047 ALX04_RS10935 629049600952be7adcf8e2a97dfa143f 216 PRINTS PR00783 Major intrinsic protein family signature 122 140 5.8E-46 T 28-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 ALX04_RS10935 629049600952be7adcf8e2a97dfa143f 216 PRINTS PR00783 Major intrinsic protein family signature 192 212 5.8E-46 T 28-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 ALX04_RS10935 629049600952be7adcf8e2a97dfa143f 216 PRINTS PR00783 Major intrinsic protein family signature 36 60 5.8E-46 T 28-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 ALX04_RS10935 629049600952be7adcf8e2a97dfa143f 216 PRINTS PR00783 Major intrinsic protein family signature 73 92 5.8E-46 T 28-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 ALX04_RS10935 629049600952be7adcf8e2a97dfa143f 216 PRINTS PR00783 Major intrinsic protein family signature 2 21 5.8E-46 T 28-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 ALX04_RS10935 629049600952be7adcf8e2a97dfa143f 216 PRINTS PR00783 Major intrinsic protein family signature 153 175 5.8E-46 T 28-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 ALX04_RS09910 708a9b3d313b7305d3c9fadd5a8c5312 244 Gene3D G3DSA:3.40.50.150 1 241 3.7E-35 T 28-03-2018 ALX04_RS09910 708a9b3d313b7305d3c9fadd5a8c5312 244 PIRSF PIRSF003078 1 223 8.1E-54 T 28-03-2018 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 ALX04_RS09910 708a9b3d313b7305d3c9fadd5a8c5312 244 SUPERFAMILY SSF53335 1 240 1.06E-39 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase ALX04_RS09910 708a9b3d313b7305d3c9fadd5a8c5312 244 Hamap MF_00074 Ribosomal RNA small subunit methyltransferase G [rsmG]. 14 217 26.639 T 28-03-2018 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 ALX04_RS09910 708a9b3d313b7305d3c9fadd5a8c5312 244 Pfam PF02527 rRNA small subunit methyltransferase G 21 197 3.7E-51 T 28-03-2018 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 ALX04_RS09910 708a9b3d313b7305d3c9fadd5a8c5312 244 TIGRFAM TIGR00138 rsmG_gidB: 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG 26 219 6.2E-47 T 28-03-2018 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 ALX04_RS01670 d7678c7a6bc7a47df2931b4c15953fff 467 TIGRFAM TIGR01887 dipeptidaselike: putative dipeptidase 13 460 3.0E-168 T 28-03-2018 IPR010964 Peptidase M20A, peptidase V-related GO:0008270|GO:0016805 ALX04_RS01670 d7678c7a6bc7a47df2931b4c15953fff 467 Gene3D G3DSA:3.30.70.360 203 282 1.5E-11 T 28-03-2018 ALX04_RS01670 d7678c7a6bc7a47df2931b4c15953fff 467 SUPERFAMILY SSF55031 186 366 3.49E-53 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain ALX04_RS01670 d7678c7a6bc7a47df2931b4c15953fff 467 SUPERFAMILY SSF53187 3 186 1.83E-64 T 28-03-2018 ALX04_RS01670 d7678c7a6bc7a47df2931b4c15953fff 467 SUPERFAMILY SSF53187 381 463 1.83E-64 T 28-03-2018 ALX04_RS01670 d7678c7a6bc7a47df2931b4c15953fff 467 Gene3D G3DSA:3.30.70.360 283 371 5.8E-30 T 28-03-2018 ALX04_RS01670 d7678c7a6bc7a47df2931b4c15953fff 467 Gene3D G3DSA:3.40.630.10 5 190 8.1E-26 T 28-03-2018 ALX04_RS01670 d7678c7a6bc7a47df2931b4c15953fff 467 Pfam PF01546 Peptidase family M20/M25/M40 84 460 6.7E-30 T 28-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 ALX04_RS07970 37598179902d401d817dff43296cd574 324 Gene3D G3DSA:3.40.50.1170 1 202 2.8E-56 T 28-03-2018 IPR027474 L-asparaginase, N-terminal Reactome: R-HSA-70614 ALX04_RS07970 37598179902d401d817dff43296cd574 324 ProSitePatterns PS00144 Asparaginase / glutaminase active site signature 1. 6 14 - T 28-03-2018 IPR020827 Asparaginase/glutaminase, active site 1 GO:0006520 ALX04_RS07970 37598179902d401d817dff43296cd574 324 Pfam PF00710 Asparaginase, N-terminal 3 188 8.9E-60 T 28-03-2018 IPR027474 L-asparaginase, N-terminal Reactome: R-HSA-70614 ALX04_RS07970 37598179902d401d817dff43296cd574 324 SMART SM00870 3 316 1.1E-143 T 28-03-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 ALX04_RS07970 37598179902d401d817dff43296cd574 324 SUPERFAMILY SSF53774 1 320 1.96E-100 T 28-03-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 ALX04_RS07970 37598179902d401d817dff43296cd574 324 PIRSF PIRSF500176 1 323 2.1E-92 T 28-03-2018 ALX04_RS07970 37598179902d401d817dff43296cd574 324 PRINTS PR00139 Asparaginase/glutaminase family signature 78 96 5.9E-17 T 28-03-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 ALX04_RS07970 37598179902d401d817dff43296cd574 324 PRINTS PR00139 Asparaginase/glutaminase family signature 138 156 5.9E-17 T 28-03-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 ALX04_RS07970 37598179902d401d817dff43296cd574 324 PRINTS PR00139 Asparaginase/glutaminase family signature 4 15 5.9E-17 T 28-03-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 ALX04_RS07970 37598179902d401d817dff43296cd574 324 Gene3D G3DSA:3.40.50.40 204 321 5.3E-29 T 28-03-2018 IPR027473 L-asparaginase, C-terminal domain Reactome: R-HSA-70614 ALX04_RS07970 37598179902d401d817dff43296cd574 324 ProSitePatterns PS00917 Asparaginase / glutaminase active site signature 2. 79 89 - T 28-03-2018 IPR027475 Asparaginase/glutaminase, active site 2 Reactome: R-HSA-70614 ALX04_RS07970 37598179902d401d817dff43296cd574 324 PIRSF PIRSF001220 1 323 1.7E-95 T 28-03-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 ALX04_RS12365 d8d1c14bc85c01e383b1eb0eb106dc83 719 Gene3D G3DSA:3.20.20.70 304 626 9.0E-49 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 ALX04_RS12365 d8d1c14bc85c01e383b1eb0eb106dc83 719 Pfam PF02065 Melibiase 287 628 8.1E-155 T 28-03-2018 IPR002252 Glycoside hydrolase family 36 GO:0004557|GO:0005975 ALX04_RS12365 d8d1c14bc85c01e383b1eb0eb106dc83 719 Gene3D G3DSA:2.60.40.1180 628 719 2.6E-15 T 28-03-2018 ALX04_RS12365 d8d1c14bc85c01e383b1eb0eb106dc83 719 Pfam PF16875 Glycosyl hydrolase family 36 N-terminal domain 30 283 1.5E-73 T 28-03-2018 IPR031704 Glycosyl hydrolase family 36, N-terminal KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 ALX04_RS12365 d8d1c14bc85c01e383b1eb0eb106dc83 719 Pfam PF16874 Glycosyl hydrolase family 36 C-terminal domain 641 716 1.5E-12 T 28-03-2018 IPR031705 Glycosyl hydrolase family 36, C-terminal KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 ALX04_RS12365 d8d1c14bc85c01e383b1eb0eb106dc83 719 PRINTS PR00743 Glycosyl hydrolase family 36 signature 239 254 3.0E-60 T 28-03-2018 IPR002252 Glycoside hydrolase family 36 GO:0004557|GO:0005975 ALX04_RS12365 d8d1c14bc85c01e383b1eb0eb106dc83 719 PRINTS PR00743 Glycosyl hydrolase family 36 signature 539 555 3.0E-60 T 28-03-2018 IPR002252 Glycoside hydrolase family 36 GO:0004557|GO:0005975 ALX04_RS12365 d8d1c14bc85c01e383b1eb0eb106dc83 719 PRINTS PR00743 Glycosyl hydrolase family 36 signature 290 310 3.0E-60 T 28-03-2018 IPR002252 Glycoside hydrolase family 36 GO:0004557|GO:0005975 ALX04_RS12365 d8d1c14bc85c01e383b1eb0eb106dc83 719 PRINTS PR00743 Glycosyl hydrolase family 36 signature 402 424 3.0E-60 T 28-03-2018 IPR002252 Glycoside hydrolase family 36 GO:0004557|GO:0005975 ALX04_RS12365 d8d1c14bc85c01e383b1eb0eb106dc83 719 PRINTS PR00743 Glycosyl hydrolase family 36 signature 324 338 3.0E-60 T 28-03-2018 IPR002252 Glycoside hydrolase family 36 GO:0004557|GO:0005975 ALX04_RS12365 d8d1c14bc85c01e383b1eb0eb106dc83 719 PRINTS PR00743 Glycosyl hydrolase family 36 signature 514 530 3.0E-60 T 28-03-2018 IPR002252 Glycoside hydrolase family 36 GO:0004557|GO:0005975 ALX04_RS12365 d8d1c14bc85c01e383b1eb0eb106dc83 719 PRINTS PR00743 Glycosyl hydrolase family 36 signature 352 367 3.0E-60 T 28-03-2018 IPR002252 Glycoside hydrolase family 36 GO:0004557|GO:0005975 ALX04_RS12365 d8d1c14bc85c01e383b1eb0eb106dc83 719 PRINTS PR00743 Glycosyl hydrolase family 36 signature 460 475 3.0E-60 T 28-03-2018 IPR002252 Glycoside hydrolase family 36 GO:0004557|GO:0005975 ALX04_RS12365 d8d1c14bc85c01e383b1eb0eb106dc83 719 PIRSF PIRSF005536 1 719 1.0E-269 T 28-03-2018 IPR002252 Glycoside hydrolase family 36 GO:0004557|GO:0005975 ALX04_RS12365 d8d1c14bc85c01e383b1eb0eb106dc83 719 Gene3D G3DSA:2.70.98.60 1 303 2.7E-81 T 28-03-2018 ALX04_RS12365 d8d1c14bc85c01e383b1eb0eb106dc83 719 SUPERFAMILY SSF51445 324 657 4.52E-87 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily ALX04_RS12365 d8d1c14bc85c01e383b1eb0eb106dc83 719 ProSitePatterns PS00512 Alpha-galactosidase signature. 353 368 - T 28-03-2018 IPR000111 Glycoside hydrolase family 27/36, conserved site GO:0004553|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 ALX04_RS07435 fc66f28495b2c58194859e118d71965b 294 SUPERFAMILY SSF53098 68 222 9.23E-34 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 ALX04_RS07435 fc66f28495b2c58194859e118d71965b 294 Gene3D G3DSA:3.30.420.10 62 224 2.8E-34 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 ALX04_RS07435 fc66f28495b2c58194859e118d71965b 294 Pfam PF00075 RNase H 67 218 1.6E-22 T 28-03-2018 IPR002156 Ribonuclease H domain GO:0003676|GO:0004523 ALX04_RS07435 fc66f28495b2c58194859e118d71965b 294 Pfam PF01693 Caulimovirus viroplasmin 4 47 2.4E-22 T 28-03-2018 IPR011320 Ribonuclease H1, N-terminal ALX04_RS07435 fc66f28495b2c58194859e118d71965b 294 Gene3D G3DSA:3.40.970.10 2 53 2.2E-23 T 28-03-2018 IPR011320 Ribonuclease H1, N-terminal ALX04_RS07435 fc66f28495b2c58194859e118d71965b 294 SUPERFAMILY SSF55658 4 48 2.46E-15 T 28-03-2018 IPR009027 Ribosomal protein L9/RNase H1, N-terminal ALX04_RS12375 04f90b307a828bc20f2b0db85dc31e52 501 Pfam PF00251 Glycosyl hydrolases family 32 N-terminal domain 37 339 9.5E-93 T 28-03-2018 IPR013148 Glycosyl hydrolase family 32, N-terminal ALX04_RS12375 04f90b307a828bc20f2b0db85dc31e52 501 ProSitePatterns PS00609 Glycosyl hydrolases family 32 active site. 37 50 - T 28-03-2018 IPR018053 Glycoside hydrolase, family 32, active site GO:0004553|GO:0005975 KEGG: 00052+3.2.1.26|KEGG: 00500+3.2.1.26 ALX04_RS12375 04f90b307a828bc20f2b0db85dc31e52 501 SMART SM00640 37 452 1.3E-129 T 28-03-2018 IPR001362 Glycoside hydrolase, family 32 GO:0004553|GO:0005975 ALX04_RS12375 04f90b307a828bc20f2b0db85dc31e52 501 SUPERFAMILY SSF75005 28 340 2.71E-94 T 28-03-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain ALX04_RS12375 04f90b307a828bc20f2b0db85dc31e52 501 SUPERFAMILY SSF49899 339 484 1.42E-18 T 28-03-2018 IPR013320 Concanavalin A-like lectin/glucanase domain ALX04_RS12375 04f90b307a828bc20f2b0db85dc31e52 501 Gene3D G3DSA:2.115.10.20 3 350 1.8E-76 T 28-03-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain ALX04_RS12375 04f90b307a828bc20f2b0db85dc31e52 501 TIGRFAM TIGR01322 scrB_fam: sucrose-6-phosphate hydrolase 22 462 9.9E-190 T 28-03-2018 IPR006232 Sucrose-6-phosphate hydrolase GO:0004564|GO:0005737|GO:0005975 KEGG: 00052+3.2.1.26|KEGG: 00500+3.2.1.26 ALX04_RS12375 04f90b307a828bc20f2b0db85dc31e52 501 Pfam PF08244 Glycosyl hydrolases family 32 C terminal 364 483 1.9E-11 T 28-03-2018 IPR013189 Glycosyl hydrolase family 32, C-terminal ALX04_RS12375 04f90b307a828bc20f2b0db85dc31e52 501 Gene3D G3DSA:2.60.120.560 351 484 3.1E-18 T 28-03-2018 ALX04_RS09845 ef63635cb828589278bd0cf3323ba525 165 Pfam PF13420 Acetyltransferase (GNAT) domain 5 157 6.7E-20 T 28-03-2018 ALX04_RS09845 ef63635cb828589278bd0cf3323ba525 165 SUPERFAMILY SSF55729 1 160 2.13E-32 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase ALX04_RS09845 ef63635cb828589278bd0cf3323ba525 165 Gene3D G3DSA:3.40.630.30 1 164 8.7E-31 T 28-03-2018 ALX04_RS12345 37824051941d9718de97beae16da86cc 756 Gene3D G3DSA:1.50.10.10 316 680 4.1E-118 T 28-03-2018 ALX04_RS12345 37824051941d9718de97beae16da86cc 756 SUPERFAMILY SSF48208 278 746 1.62E-139 T 28-03-2018 IPR008928 Six-hairpin glycosidase-like GO:0003824 ALX04_RS12345 37824051941d9718de97beae16da86cc 756 Gene3D G3DSA:2.60.420.10 681 752 1.1E-25 T 28-03-2018 ALX04_RS12345 37824051941d9718de97beae16da86cc 756 Gene3D G3DSA:2.70.98.40 1 268 1.8E-61 T 28-03-2018 IPR005196 Glycoside hydrolase, family 65, N-terminal GO:0003824|GO:0005975 ALX04_RS12345 37824051941d9718de97beae16da86cc 756 Pfam PF03636 Glycosyl hydrolase family 65, N-terminal domain 15 265 1.4E-50 T 28-03-2018 IPR005196 Glycoside hydrolase, family 65, N-terminal GO:0003824|GO:0005975 ALX04_RS12345 37824051941d9718de97beae16da86cc 756 SUPERFAMILY SSF74650 1 267 1.35E-81 T 28-03-2018 IPR011013 Galactose mutarotase-like domain GO:0003824|GO:0005975|GO:0030246 ALX04_RS12345 37824051941d9718de97beae16da86cc 756 Pfam PF03632 Glycosyl hydrolase family 65 central catalytic domain 322 695 9.3E-150 T 28-03-2018 IPR005195 Glycoside hydrolase, family 65, central catalytic GO:0003824|GO:0005975 ALX04_RS12345 37824051941d9718de97beae16da86cc 756 Pfam PF03633 Glycosyl hydrolase family 65, C-terminal domain 699 749 6.2E-17 T 28-03-2018 IPR005194 Glycoside hydrolase family 65, C-terminal ALX04_RS12345 37824051941d9718de97beae16da86cc 756 PIRSF PIRSF036289 1 756 3.3E-284 T 28-03-2018 IPR017045 Maltose phosphorylase/glycosyl hydrolase/vacuolar acid trehalase ALX04_RS03785 7f95f68ed8a2c1ed72ff1c7b56368387 441 Pfam PF01134 Glucose inhibited division protein A 7 367 1.6E-109 T 28-03-2018 IPR002218 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG-related GO:0008033|GO:0050660 Reactome: R-HSA-6787450 ALX04_RS03785 7f95f68ed8a2c1ed72ff1c7b56368387 441 TIGRFAM TIGR00137 gid_trmFO: tRNA:m(5)U-54 methyltransferase 6 434 1.0E-216 T 28-03-2018 IPR004417 Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO GO:0005737|GO:0008033|GO:0047151|GO:0050660 ALX04_RS03785 7f95f68ed8a2c1ed72ff1c7b56368387 441 SUPERFAMILY SSF51905 6 368 4.37E-28 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ALX04_RS03785 7f95f68ed8a2c1ed72ff1c7b56368387 441 Gene3D G3DSA:3.50.50.60 4 372 2.2E-18 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ALX04_RS03785 7f95f68ed8a2c1ed72ff1c7b56368387 441 Hamap MF_01037 Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO [trmFO]. 7 435 35.513 T 28-03-2018 IPR004417 Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO GO:0005737|GO:0008033|GO:0047151|GO:0050660 ALX04_RS03785 7f95f68ed8a2c1ed72ff1c7b56368387 441 ProSitePatterns PS01281 Glucose inhibited division protein A family signature 2. 338 361 - T 28-03-2018 IPR020595 MnmG-related, conserved site Reactome: R-HSA-6787450 ALX04_RS07345 fd5d10ba69810b9650979fa98306fb0c 274 Pfam PF00106 short chain dehydrogenase 3 191 4.6E-42 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR ALX04_RS07345 fd5d10ba69810b9650979fa98306fb0c 274 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 75 86 1.9E-18 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR ALX04_RS07345 fd5d10ba69810b9650979fa98306fb0c 274 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 122 138 1.9E-18 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR ALX04_RS07345 fd5d10ba69810b9650979fa98306fb0c 274 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 3 20 1.9E-18 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR ALX04_RS07345 fd5d10ba69810b9650979fa98306fb0c 274 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 148 167 1.9E-18 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR ALX04_RS07345 fd5d10ba69810b9650979fa98306fb0c 274 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 169 186 1.9E-18 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR ALX04_RS07345 fd5d10ba69810b9650979fa98306fb0c 274 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 148 167 2.9E-12 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR ALX04_RS07345 fd5d10ba69810b9650979fa98306fb0c 274 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 128 136 2.9E-12 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR ALX04_RS07345 fd5d10ba69810b9650979fa98306fb0c 274 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 75 86 2.9E-12 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR ALX04_RS07345 fd5d10ba69810b9650979fa98306fb0c 274 SUPERFAMILY SSF51735 1 236 4.96E-49 T 28-03-2018 IPR016040 NAD(P)-binding domain ALX04_RS07345 fd5d10ba69810b9650979fa98306fb0c 274 Gene3D G3DSA:3.40.50.720 1 271 6.4E-46 T 28-03-2018 ALX04_RS07345 fd5d10ba69810b9650979fa98306fb0c 274 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 135 163 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 ALX04_RS12195 4dd5fb4f4073447fce3e5fc0c436956d 279 Pfam PF02361 Cobalt transport protein 14 236 4.1E-23 T 28-03-2018 IPR003339 ABC/ECF transporter, transmembrane component ALX04_RS10330 4c26ab37acd7cab042bf4a4494ba6a66 122 SUPERFAMILY SSF55620 3 116 1.11E-31 T 28-03-2018 ALX04_RS10330 4c26ab37acd7cab042bf4a4494ba6a66 122 SMART SM00905 4 117 7.7E-39 T 28-03-2018 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 ALX04_RS10330 4c26ab37acd7cab042bf4a4494ba6a66 122 Gene3D G3DSA:3.30.1130.10 1 118 1.4E-29 T 28-03-2018 ALX04_RS10330 4c26ab37acd7cab042bf4a4494ba6a66 122 TIGRFAM TIGR00526 folB_dom: FolB domain 3 116 3.2E-25 T 28-03-2018 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 ALX04_RS10330 4c26ab37acd7cab042bf4a4494ba6a66 122 TIGRFAM TIGR00525 folB: dihydroneopterin aldolase 4 116 2.3E-25 T 28-03-2018 IPR006156 Dihydroneopterin aldolase GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 ALX04_RS10330 4c26ab37acd7cab042bf4a4494ba6a66 122 Pfam PF02152 Dihydroneopterin aldolase 4 116 2.0E-29 T 28-03-2018 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 ALX04_RS13305 b1332dd1e98d33b3aa85c40ff8d1a9f7 205 SMART SM01266 5 59 3.5E-12 T 28-03-2018 IPR024688 Maltose/galactoside acetyltransferase GO:0016407 ALX04_RS13305 b1332dd1e98d33b3aa85c40ff8d1a9f7 205 SUPERFAMILY SSF51161 5 197 9.7E-50 T 28-03-2018 IPR011004 Trimeric LpxA-like ALX04_RS13305 b1332dd1e98d33b3aa85c40ff8d1a9f7 205 Pfam PF12464 Maltose acetyltransferase 10 58 2.0E-10 T 28-03-2018 IPR024688 Maltose/galactoside acetyltransferase GO:0016407 ALX04_RS13305 b1332dd1e98d33b3aa85c40ff8d1a9f7 205 Pfam PF14602 Hexapeptide repeat of succinyl-transferase 131 166 7.9E-13 T 28-03-2018 IPR001451 Hexapeptide repeat ALX04_RS13305 b1332dd1e98d33b3aa85c40ff8d1a9f7 205 Gene3D G3DSA:2.160.10.10 2 199 9.3E-44 T 28-03-2018 ALX04_RS02885 d4d3a5d041760a30fb26d6fbcada2fe1 484 SUPERFAMILY SSF47446 328 431 1.05E-35 T 28-03-2018 IPR004125 Signal recognition particle, SRP54 subunit, M-domain GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 ALX04_RS02885 d4d3a5d041760a30fb26d6fbcada2fe1 484 SMART SM00962 101 297 3.1E-118 T 28-03-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 ALX04_RS02885 d4d3a5d041760a30fb26d6fbcada2fe1 484 Gene3D G3DSA:1.20.120.140 1 92 4.8E-28 T 28-03-2018 ALX04_RS02885 d4d3a5d041760a30fb26d6fbcada2fe1 484 SMART SM00963 2 87 2.7E-29 T 28-03-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 ALX04_RS02885 d4d3a5d041760a30fb26d6fbcada2fe1 484 Pfam PF02881 SRP54-type protein, helical bundle domain 6 83 2.4E-21 T 28-03-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 ALX04_RS02885 d4d3a5d041760a30fb26d6fbcada2fe1 484 Hamap MF_00306 Signal recognition particle 54 kDa protein [srp54]. 6 442 34.044 T 28-03-2018 IPR022941 Signal recognition particle, SRP54 subunit GO:0003924|GO:0005525|GO:0006614|GO:0048500 Reactome: R-HSA-1799339 ALX04_RS02885 d4d3a5d041760a30fb26d6fbcada2fe1 484 Gene3D G3DSA:1.10.260.30 328 432 9.5E-37 T 28-03-2018 IPR004125 Signal recognition particle, SRP54 subunit, M-domain GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 ALX04_RS02885 d4d3a5d041760a30fb26d6fbcada2fe1 484 Gene3D G3DSA:3.40.50.300 102 172 6.8E-8 T 28-03-2018 ALX04_RS02885 d4d3a5d041760a30fb26d6fbcada2fe1 484 Pfam PF02978 Signal peptide binding domain 328 427 2.0E-31 T 28-03-2018 IPR004125 Signal recognition particle, SRP54 subunit, M-domain GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 ALX04_RS02885 d4d3a5d041760a30fb26d6fbcada2fe1 484 Pfam PF00448 SRP54-type protein, GTPase domain 101 297 1.7E-77 T 28-03-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 ALX04_RS02885 d4d3a5d041760a30fb26d6fbcada2fe1 484 Gene3D G3DSA:1.20.120.140 196 311 4.1E-34 T 28-03-2018 ALX04_RS02885 d4d3a5d041760a30fb26d6fbcada2fe1 484 SMART SM00382 100 302 7.0E-7 T 28-03-2018 IPR003593 AAA+ ATPase domain ALX04_RS02885 d4d3a5d041760a30fb26d6fbcada2fe1 484 TIGRFAM TIGR00959 ffh: signal recognition particle protein 3 428 3.7E-187 T 28-03-2018 IPR004780 Signal recognition particle protein Ffh GO:0003924|GO:0005525|GO:0006614|GO:0048500 ALX04_RS02885 d4d3a5d041760a30fb26d6fbcada2fe1 484 SUPERFAMILY SSF52540 43 355 2.12E-56 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase ALX04_RS08380 7f75536228ac19a94a6bd2bc863cc503 388 Pfam PF00999 Sodium/hydrogen exchanger family 9 380 5.8E-76 T 28-03-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 ALX04_RS08380 7f75536228ac19a94a6bd2bc863cc503 388 TIGRFAM TIGR00932 2a37: transporter, monovalent cation:proton antiporter-2 (CPA2) family 12 287 4.3E-74 T 28-03-2018 IPR004771 K+/H+ exchanger GO:0006812|GO:0008324|GO:0016021 ALX04_RS08380 7f75536228ac19a94a6bd2bc863cc503 388 Gene3D G3DSA:1.20.91.10 232 323 1.6E-15 T 28-03-2018 ALX04_RS11635 80d3c43565aea966e81d1bb46b0fc3af 265 SUPERFAMILY SSF53633 10 264 1.06E-63 T 28-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase ALX04_RS11635 80d3c43565aea966e81d1bb46b0fc3af 265 PRINTS PR00474 Glutamate 5-kinase family signature 47 61 2.9E-50 T 28-03-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 ALX04_RS11635 80d3c43565aea966e81d1bb46b0fc3af 265 PRINTS PR00474 Glutamate 5-kinase family signature 218 238 2.9E-50 T 28-03-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 ALX04_RS11635 80d3c43565aea966e81d1bb46b0fc3af 265 PRINTS PR00474 Glutamate 5-kinase family signature 157 184 2.9E-50 T 28-03-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 ALX04_RS11635 80d3c43565aea966e81d1bb46b0fc3af 265 PRINTS PR00474 Glutamate 5-kinase family signature 81 109 2.9E-50 T 28-03-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 ALX04_RS11635 80d3c43565aea966e81d1bb46b0fc3af 265 PRINTS PR00474 Glutamate 5-kinase family signature 121 142 2.9E-50 T 28-03-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 ALX04_RS11635 80d3c43565aea966e81d1bb46b0fc3af 265 ProSitePatterns PS00902 Glutamate 5-kinase signature. 216 233 - T 28-03-2018 IPR019797 Glutamate 5-kinase, conserved site GO:0004349|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 ALX04_RS11635 80d3c43565aea966e81d1bb46b0fc3af 265 Gene3D G3DSA:3.40.1160.10 4 265 3.3E-53 T 28-03-2018 ALX04_RS11635 80d3c43565aea966e81d1bb46b0fc3af 265 Hamap MF_00456 Glutamate 5-kinase [proB]. 10 265 35.419 T 28-03-2018 IPR005715 Glutamate 5-kinase/delta-1-pyrroline-5-carboxylate synthase GO:0005737|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 ALX04_RS11635 80d3c43565aea966e81d1bb46b0fc3af 265 Pfam PF00696 Amino acid kinase family 10 237 2.6E-33 T 28-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase ALX04_RS11635 80d3c43565aea966e81d1bb46b0fc3af 265 TIGRFAM TIGR01027 proB: glutamate 5-kinase 10 264 5.1E-87 T 28-03-2018 IPR005715 Glutamate 5-kinase/delta-1-pyrroline-5-carboxylate synthase GO:0005737|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 ALX04_RS11635 80d3c43565aea966e81d1bb46b0fc3af 265 PIRSF PIRSF000729 5 265 1.0E-89 T 28-03-2018 IPR011529 Glutamate 5-kinase GO:0004349|GO:0005737|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922 ALX04_RS02185 13732bbaad8b6b8c8dbc064835bd87e5 226 Pfam PF13731 WxL domain surface cell wall-binding 26 222 4.5E-36 T 28-03-2018 IPR027994 WxL domain ALX04_RS10505 71e970b6cfe209527c330d462ccf61d4 134 TIGRFAM TIGR01617 arsC_related: transcriptional regulator, Spx/MgsR family 3 116 7.0E-29 T 28-03-2018 IPR006504 Transcriptional regulator Spx/MgsR ALX04_RS10505 71e970b6cfe209527c330d462ccf61d4 134 Pfam PF03960 ArsC family 44 115 1.8E-16 T 28-03-2018 IPR006660 Arsenate reductase-like ALX04_RS10505 71e970b6cfe209527c330d462ccf61d4 134 SUPERFAMILY SSF52833 1 127 1.02E-24 T 28-03-2018 IPR012336 Thioredoxin-like fold ALX04_RS10505 71e970b6cfe209527c330d462ccf61d4 134 Gene3D G3DSA:3.40.30.10 1 133 8.0E-28 T 28-03-2018 ALX04_RS14060 805a62a92e5923e5a65cfacfd0960da4 233 SMART SM00345 9 68 2.8E-25 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 ALX04_RS14060 805a62a92e5923e5a65cfacfd0960da4 233 SUPERFAMILY SSF46785 3 72 7.36E-26 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS14060 805a62a92e5923e5a65cfacfd0960da4 233 SUPERFAMILY SSF64288 56 231 4.71E-48 T 28-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain ALX04_RS14060 805a62a92e5923e5a65cfacfd0960da4 233 Pfam PF07702 UTRA domain 89 228 1.2E-37 T 28-03-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 ALX04_RS14060 805a62a92e5923e5a65cfacfd0960da4 233 SMART SM00866 89 228 1.2E-40 T 28-03-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 ALX04_RS14060 805a62a92e5923e5a65cfacfd0960da4 233 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 42 58 3.0E-11 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 ALX04_RS14060 805a62a92e5923e5a65cfacfd0960da4 233 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 28 42 3.0E-11 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 ALX04_RS14060 805a62a92e5923e5a65cfacfd0960da4 233 Gene3D G3DSA:3.40.1410.10 68 232 4.8E-42 T 28-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain ALX04_RS14060 805a62a92e5923e5a65cfacfd0960da4 233 Pfam PF00392 Bacterial regulatory proteins, gntR family 6 68 5.5E-23 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 ALX04_RS14060 805a62a92e5923e5a65cfacfd0960da4 233 Gene3D G3DSA:1.10.10.10 1 67 8.3E-25 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS12285 bdd1f3941bd330ddb8fe25235b9595dd 193 Pfam PF02734 DAK2 domain 31 187 1.0E-43 T 28-03-2018 IPR004007 DhaL domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 ALX04_RS12285 bdd1f3941bd330ddb8fe25235b9595dd 193 TIGRFAM TIGR02365 dha_L_ycgS: dihydroxyacetone kinase, L subunit 9 187 8.6E-68 T 28-03-2018 IPR012737 Dihydroxyacetone kinase, subunit L GO:0016772 ALX04_RS12285 bdd1f3941bd330ddb8fe25235b9595dd 193 SUPERFAMILY SSF101473 5 188 7.98E-53 T 28-03-2018 IPR004007 DhaL domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 ALX04_RS12285 bdd1f3941bd330ddb8fe25235b9595dd 193 SMART SM01120 31 188 1.7E-64 T 28-03-2018 IPR004007 DhaL domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 ALX04_RS10980 17067db9a146e2c498d8c2bb8a22e22d 425 Pfam PF07690 Major Facilitator Superfamily 25 378 2.7E-20 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 ALX04_RS10980 17067db9a146e2c498d8c2bb8a22e22d 425 Gene3D G3DSA:1.20.1250.20 209 420 6.8E-14 T 28-03-2018 ALX04_RS10980 17067db9a146e2c498d8c2bb8a22e22d 425 Gene3D G3DSA:1.20.1250.20 7 208 2.9E-21 T 28-03-2018 ALX04_RS10980 17067db9a146e2c498d8c2bb8a22e22d 425 SUPERFAMILY SSF103473 15 419 1.31E-42 T 28-03-2018 IPR020846 Major facilitator superfamily domain ALX04_RS00765 bb67045cc71c817eac32445952a6d5fd 547 Pfam PF00390 Malic enzyme, N-terminal domain 70 251 7.2E-64 T 28-03-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 ALX04_RS00765 bb67045cc71c817eac32445952a6d5fd 547 Pfam PF03949 Malic enzyme, NAD binding domain 261 515 2.0E-94 T 28-03-2018 IPR012302 Malic enzyme, NAD-binding GO:0051287 ALX04_RS00765 bb67045cc71c817eac32445952a6d5fd 547 ProSitePatterns PS00331 Malic enzymes signature. 257 273 - T 28-03-2018 IPR015884 Malic enzyme, conserved site GO:0004471|GO:0055114 ALX04_RS00765 bb67045cc71c817eac32445952a6d5fd 547 SMART SM01274 69 251 4.9E-82 T 28-03-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 ALX04_RS00765 bb67045cc71c817eac32445952a6d5fd 547 PIRSF PIRSF000106 1 547 5.8E-207 T 28-03-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 ALX04_RS00765 bb67045cc71c817eac32445952a6d5fd 547 PRINTS PR00072 Malic enzyme signature 232 250 3.4E-68 T 28-03-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 ALX04_RS00765 bb67045cc71c817eac32445952a6d5fd 547 PRINTS PR00072 Malic enzyme signature 75 99 3.4E-68 T 28-03-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 ALX04_RS00765 bb67045cc71c817eac32445952a6d5fd 547 PRINTS PR00072 Malic enzyme signature 257 273 3.4E-68 T 28-03-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 ALX04_RS00765 bb67045cc71c817eac32445952a6d5fd 547 PRINTS PR00072 Malic enzyme signature 173 195 3.4E-68 T 28-03-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 ALX04_RS00765 bb67045cc71c817eac32445952a6d5fd 547 PRINTS PR00072 Malic enzyme signature 288 304 3.4E-68 T 28-03-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 ALX04_RS00765 bb67045cc71c817eac32445952a6d5fd 547 PRINTS PR00072 Malic enzyme signature 395 411 3.4E-68 T 28-03-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 ALX04_RS00765 bb67045cc71c817eac32445952a6d5fd 547 PRINTS PR00072 Malic enzyme signature 137 166 3.4E-68 T 28-03-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 ALX04_RS00765 bb67045cc71c817eac32445952a6d5fd 547 SUPERFAMILY SSF53223 5 260 5.04E-95 T 28-03-2018 ALX04_RS00765 bb67045cc71c817eac32445952a6d5fd 547 Gene3D G3DSA:3.40.50.720 259 546 1.1E-94 T 28-03-2018 ALX04_RS00765 bb67045cc71c817eac32445952a6d5fd 547 SMART SM00919 261 517 2.1E-106 T 28-03-2018 IPR012302 Malic enzyme, NAD-binding GO:0051287 ALX04_RS00765 bb67045cc71c817eac32445952a6d5fd 547 Gene3D G3DSA:3.40.50.10380 3 258 4.3E-94 T 28-03-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 ALX04_RS00765 bb67045cc71c817eac32445952a6d5fd 547 SUPERFAMILY SSF51735 261 544 4.33E-83 T 28-03-2018 IPR016040 NAD(P)-binding domain ALX04_RS10350 d11b60a246302bb0c9f29df791516e8b 471 Gene3D G3DSA:1.20.1250.20 7 202 3.3E-29 T 28-03-2018 ALX04_RS10350 d11b60a246302bb0c9f29df791516e8b 471 Pfam PF07690 Major Facilitator Superfamily 22 412 6.6E-37 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 ALX04_RS10350 d11b60a246302bb0c9f29df791516e8b 471 Gene3D G3DSA:1.20.1250.20 261 469 1.4E-23 T 28-03-2018 ALX04_RS10350 d11b60a246302bb0c9f29df791516e8b 471 SUPERFAMILY SSF103473 251 467 4.97E-58 T 28-03-2018 IPR020846 Major facilitator superfamily domain ALX04_RS10350 d11b60a246302bb0c9f29df791516e8b 471 SUPERFAMILY SSF103473 8 201 4.97E-58 T 28-03-2018 IPR020846 Major facilitator superfamily domain ALX04_RS04675 9d5c0c1eeeb37b2cca4b5312ed8e457e 252 Gene3D G3DSA:3.40.50.150 31 217 2.0E-34 T 28-03-2018 ALX04_RS04675 9d5c0c1eeeb37b2cca4b5312ed8e457e 252 SUPERFAMILY SSF53335 9 218 2.56E-29 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase ALX04_RS04675 9d5c0c1eeeb37b2cca4b5312ed8e457e 252 Pfam PF05175 Methyltransferase small domain 37 147 5.6E-11 T 28-03-2018 IPR007848 Methyltransferase small domain GO:0008168 ALX04_RS04675 9d5c0c1eeeb37b2cca4b5312ed8e457e 252 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 122 128 - T 28-03-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 ALX04_RS01705 9ec400e5115a0aedf762ab94156836e7 215 SUPERFAMILY SSF52540 6 195 8.88E-42 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase ALX04_RS01705 9ec400e5115a0aedf762ab94156836e7 215 Pfam PF01712 Deoxynucleoside kinase 5 203 5.9E-52 T 28-03-2018 IPR031314 Deoxynucleoside kinase domain ALX04_RS01705 9ec400e5115a0aedf762ab94156836e7 215 PIRSF PIRSF000705 1 215 7.5E-59 T 28-03-2018 IPR002624 Deoxynucleoside kinase GO:0005524|GO:0006139|GO:0019206 ALX04_RS01705 9ec400e5115a0aedf762ab94156836e7 215 Gene3D G3DSA:3.40.50.300 1 210 1.8E-38 T 28-03-2018 ALX04_RS03925 0c3cd7e6e7958406caaa8f4dba96e0ea 228 Gene3D G3DSA:3.40.50.300 4 224 4.4E-48 T 28-03-2018 ALX04_RS03925 0c3cd7e6e7958406caaa8f4dba96e0ea 228 TIGRFAM TIGR00017 cmk: cytidylate kinase 5 217 8.4E-78 T 28-03-2018 IPR003136 Cytidylate kinase GO:0004127|GO:0005524|GO:0006139 KEGG: 00240+2.7.4.25|MetaCyc: PWY-7205 ALX04_RS03925 0c3cd7e6e7958406caaa8f4dba96e0ea 228 SUPERFAMILY SSF52540 8 221 1.15E-43 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase ALX04_RS03925 0c3cd7e6e7958406caaa8f4dba96e0ea 228 Pfam PF02224 Cytidylate kinase 8 221 3.2E-77 T 28-03-2018 IPR011994 Cytidylate kinase domain GO:0004127|GO:0005524|GO:0006139 KEGG: 00240+2.7.4.25|MetaCyc: PWY-7205 ALX04_RS03925 0c3cd7e6e7958406caaa8f4dba96e0ea 228 Hamap MF_00238 Cytidylate kinase [cmk]. 6 224 34.053 T 28-03-2018 IPR003136 Cytidylate kinase GO:0004127|GO:0005524|GO:0006139 KEGG: 00240+2.7.4.25|MetaCyc: PWY-7205 ALX04_RS01180 8d6ea1adcd03e7d1630834bb0cde57ec 377 Gene3D G3DSA:3.40.50.720 295 377 2.1E-13 T 28-03-2018 ALX04_RS01180 8d6ea1adcd03e7d1630834bb0cde57ec 377 Gene3D G3DSA:3.40.50.720 2 294 3.1E-40 T 28-03-2018 ALX04_RS01180 8d6ea1adcd03e7d1630834bb0cde57ec 377 SUPERFAMILY SSF54373 253 322 4.51E-25 T 28-03-2018 ALX04_RS01180 8d6ea1adcd03e7d1630834bb0cde57ec 377 Pfam PF03275 UDP-galactopyranose mutase 151 355 3.7E-86 T 28-03-2018 IPR015899 UDP-galactopyranose mutase, C-terminal GO:0008767 KEGG: 00052+5.4.99.9|KEGG: 00520+5.4.99.9|MetaCyc: PWY-6397|MetaCyc: PWY-7328|MetaCyc: PWY-7622 ALX04_RS01180 8d6ea1adcd03e7d1630834bb0cde57ec 377 SUPERFAMILY SSF51971 340 369 3.65E-50 T 28-03-2018 ALX04_RS01180 8d6ea1adcd03e7d1630834bb0cde57ec 377 SUPERFAMILY SSF51971 4 270 3.65E-50 T 28-03-2018 ALX04_RS01180 8d6ea1adcd03e7d1630834bb0cde57ec 377 Pfam PF13450 NAD(P)-binding Rossmann-like domain 9 75 2.4E-18 T 28-03-2018 ALX04_RS01180 8d6ea1adcd03e7d1630834bb0cde57ec 377 TIGRFAM TIGR00031 UDP-GALP_mutase: UDP-galactopyranose mutase 4 369 1.8E-130 T 28-03-2018 IPR004379 UDP-galactopyranose mutase GO:0008767 KEGG: 00052+5.4.99.9|KEGG: 00520+5.4.99.9|MetaCyc: PWY-6397|MetaCyc: PWY-7328|MetaCyc: PWY-7622 ALX04_RS09635 7e87863762f75df3f58878da9badf852 376 Pfam PF00589 Phage integrase family 193 355 5.7E-24 T 28-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 ALX04_RS09635 7e87863762f75df3f58878da9badf852 376 Gene3D G3DSA:1.10.150.130 56 170 1.8E-16 T 28-03-2018 IPR023109 Integrase/recombinase, N-terminal ALX04_RS09635 7e87863762f75df3f58878da9badf852 376 Gene3D G3DSA:1.10.443.10 171 365 5.5E-31 T 28-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 ALX04_RS09635 7e87863762f75df3f58878da9badf852 376 Pfam PF13102 Phage integrase SAM-like domain 63 149 2.5E-10 T 28-03-2018 IPR025269 Phage integrase SAM-like domain ALX04_RS09635 7e87863762f75df3f58878da9badf852 376 SUPERFAMILY SSF56349 63 363 2.44E-53 T 28-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 ALX04_RS03975 87cfe00d78962091e5a188606e40ae3e 296 Hamap MF_01807 Tyrosine recombinase XerD [xerD]. 1 296 55.219 T 28-03-2018 IPR011932 Tyrosine recombinase XerD GO:0006310|GO:0009009 ALX04_RS03975 87cfe00d78962091e5a188606e40ae3e 296 Gene3D G3DSA:1.10.443.10 110 290 1.5E-51 T 28-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 ALX04_RS03975 87cfe00d78962091e5a188606e40ae3e 296 Pfam PF02899 Phage integrase, N-terminal SAM-like domain 5 86 3.2E-15 T 28-03-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 ALX04_RS03975 87cfe00d78962091e5a188606e40ae3e 296 SUPERFAMILY SSF56349 5 290 9.12E-60 T 28-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 ALX04_RS03975 87cfe00d78962091e5a188606e40ae3e 296 TIGRFAM TIGR02225 recomb_XerD: tyrosine recombinase XerD 7 296 2.5E-119 T 28-03-2018 IPR011932 Tyrosine recombinase XerD GO:0006310|GO:0009009 ALX04_RS03975 87cfe00d78962091e5a188606e40ae3e 296 Pfam PF00589 Phage integrase family 110 282 3.2E-51 T 28-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 ALX04_RS03975 87cfe00d78962091e5a188606e40ae3e 296 Hamap MF_01808 Tyrosine recombinase XerC [xerC]. 3 296 53.818 T 28-03-2018 IPR023009 Tyrosine recombinase XerC/XerD ALX04_RS03975 87cfe00d78962091e5a188606e40ae3e 296 Gene3D G3DSA:1.10.150.130 1 109 1.4E-20 T 28-03-2018 IPR023109 Integrase/recombinase, N-terminal ALX04_RS07935 e473b80cab51416c8735e304b27472f8 161 Hamap MF_01929 N5-carboxyaminoimidazole ribonucleotide mutase [purE]. 5 158 31.709 T 28-03-2018 IPR033747 Class I PurE ALX04_RS07935 e473b80cab51416c8735e304b27472f8 161 SMART SM01001 3 154 1.9E-91 T 28-03-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 ALX04_RS07935 e473b80cab51416c8735e304b27472f8 161 PIRSF PIRSF001338 1 161 8.9E-67 T 28-03-2018 IPR024694 PurE, prokaryotic type GO:0006189 KEGG: 00230+5.4.99.18|MetaCyc: PWY-6123|MetaCyc: PWY-7234 ALX04_RS07935 e473b80cab51416c8735e304b27472f8 161 Gene3D G3DSA:3.40.50.7700 1 161 1.4E-62 T 28-03-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 ALX04_RS07935 e473b80cab51416c8735e304b27472f8 161 TIGRFAM TIGR01162 purE: phosphoribosylaminoimidazole carboxylase, catalytic subunit 5 159 1.0E-59 T 28-03-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 ALX04_RS07935 e473b80cab51416c8735e304b27472f8 161 Pfam PF00731 AIR carboxylase 4 152 1.1E-60 T 28-03-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 ALX04_RS07935 e473b80cab51416c8735e304b27472f8 161 SUPERFAMILY SSF52255 4 158 1.96E-61 T 28-03-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 ALX04_RS03960 fad1c28c8be8933c0d17059b5d07ae58 199 Gene3D G3DSA:1.10.10.10 3 82 2.0E-14 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS03960 fad1c28c8be8933c0d17059b5d07ae58 199 SUPERFAMILY SSF46785 84 157 6.97E-26 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS03960 fad1c28c8be8933c0d17059b5d07ae58 199 TIGRFAM TIGR00281 TIGR00281: segregation and condensation protein B 6 174 3.3E-49 T 28-03-2018 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 ALX04_RS03960 fad1c28c8be8933c0d17059b5d07ae58 199 Pfam PF04079 Segregation and condensation complex subunit ScpB 6 165 4.0E-53 T 28-03-2018 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 ALX04_RS03960 fad1c28c8be8933c0d17059b5d07ae58 199 Gene3D G3DSA:1.10.10.10 83 174 3.1E-29 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS03960 fad1c28c8be8933c0d17059b5d07ae58 199 Hamap MF_01804 Segregation and condensation protein B [scpB]. 1 184 34.061 T 28-03-2018 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 ALX04_RS03960 fad1c28c8be8933c0d17059b5d07ae58 199 PIRSF PIRSF019345 1 199 4.5E-50 T 28-03-2018 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 ALX04_RS03960 fad1c28c8be8933c0d17059b5d07ae58 199 SUPERFAMILY SSF46785 5 79 3.19E-11 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS10835 b9ac318c9f0c212b3843d4c6564e60f1 106 Gene3D G3DSA:3.40.30.10 2 69 7.5E-21 T 28-03-2018 ALX04_RS10835 b9ac318c9f0c212b3843d4c6564e60f1 106 SUPERFAMILY SSF52833 2 105 9.01E-29 T 28-03-2018 IPR012336 Thioredoxin-like fold ALX04_RS10835 b9ac318c9f0c212b3843d4c6564e60f1 106 Pfam PF00085 Thioredoxin 3 103 1.7E-23 T 28-03-2018 IPR013766 Thioredoxin domain GO:0045454 ALX04_RS10835 b9ac318c9f0c212b3843d4c6564e60f1 106 Gene3D G3DSA:3.40.30.10 70 106 1.7E-6 T 28-03-2018 ALX04_RS10835 b9ac318c9f0c212b3843d4c6564e60f1 106 PRINTS PR00421 Thioredoxin family signature 19 27 4.3E-5 T 28-03-2018 ALX04_RS10835 b9ac318c9f0c212b3843d4c6564e60f1 106 PRINTS PR00421 Thioredoxin family signature 27 36 4.3E-5 T 28-03-2018 ALX04_RS10835 b9ac318c9f0c212b3843d4c6564e60f1 106 PRINTS PR00421 Thioredoxin family signature 69 80 4.3E-5 T 28-03-2018 ALX04_RS10835 b9ac318c9f0c212b3843d4c6564e60f1 106 PIRSF PIRSF000077 1 105 4.1E-30 T 28-03-2018 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 ALX04_RS03875 893472b743348e8940d62615b79e97c6 636 Gene3D G3DSA:3.40.50.300 1 293 3.6E-53 T 28-03-2018 ALX04_RS03875 893472b743348e8940d62615b79e97c6 636 ProSitePatterns PS00211 ABC transporters family signature. 159 173 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 ALX04_RS03875 893472b743348e8940d62615b79e97c6 636 SUPERFAMILY SSF52540 314 518 1.37E-44 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase ALX04_RS03875 893472b743348e8940d62615b79e97c6 636 Pfam PF12848 ABC transporter 226 294 5.2E-11 T 28-03-2018 IPR032781 ABC-transporter extension domain ALX04_RS03875 893472b743348e8940d62615b79e97c6 636 Pfam PF16326 ABC transporter C-terminal domain 566 631 6.0E-18 T 28-03-2018 IPR032524 ABC transporter Uup, C-terminal GO:0003677 ALX04_RS03875 893472b743348e8940d62615b79e97c6 636 SUPERFAMILY SSF52540 4 241 1.63E-46 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase ALX04_RS03875 893472b743348e8940d62615b79e97c6 636 Gene3D G3DSA:3.40.50.300 294 551 6.1E-49 T 28-03-2018 ALX04_RS03875 893472b743348e8940d62615b79e97c6 636 Pfam PF00005 ABC transporter 20 187 4.9E-24 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 ALX04_RS03875 893472b743348e8940d62615b79e97c6 636 Pfam PF00005 ABC transporter 335 470 1.4E-20 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 ALX04_RS03875 893472b743348e8940d62615b79e97c6 636 SMART SM00382 344 521 3.7E-7 T 28-03-2018 IPR003593 AAA+ ATPase domain ALX04_RS03875 893472b743348e8940d62615b79e97c6 636 SMART SM00382 28 239 6.1E-6 T 28-03-2018 IPR003593 AAA+ ATPase domain ALX04_RS00330 89c33b1743d3287b8073ee91eab98a09 155 Pfam PF05848 Firmicute transcriptional repressor of class III stress genes (CtsR) 4 151 3.2E-53 T 28-03-2018 IPR008463 Transcriptional repressor of class III stress genes GO:0003677|GO:0006355|GO:0006950 ALX04_RS00330 89c33b1743d3287b8073ee91eab98a09 155 PIRSF PIRSF010607 1 155 2.7E-63 T 28-03-2018 IPR008463 Transcriptional repressor of class III stress genes GO:0003677|GO:0006355|GO:0006950 ALX04_RS00330 89c33b1743d3287b8073ee91eab98a09 155 Gene3D G3DSA:1.10.10.10 1 72 0.0017 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS04225 f63c4d6aeb64dae33464e3f104e83f59 314 SUPERFAMILY SSF50129 1 153 1.02E-40 T 28-03-2018 IPR011032 GroES-like ALX04_RS04225 f63c4d6aeb64dae33464e3f104e83f59 314 SUPERFAMILY SSF51735 120 245 7.89E-33 T 28-03-2018 IPR016040 NAD(P)-binding domain ALX04_RS04225 f63c4d6aeb64dae33464e3f104e83f59 314 SMART SM00829 10 308 7.3E-23 T 28-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 ALX04_RS04225 f63c4d6aeb64dae33464e3f104e83f59 314 Gene3D G3DSA:3.40.50.720 158 238 4.9E-12 T 28-03-2018 ALX04_RS04225 f63c4d6aeb64dae33464e3f104e83f59 314 ProSitePatterns PS01162 Quinone oxidoreductase / zeta-crystallin signature. 148 169 - T 28-03-2018 IPR002364 Quinone oxidoreductase/zeta-crystallin, conserved site GO:0008270|GO:0016491 ALX04_RS04225 f63c4d6aeb64dae33464e3f104e83f59 314 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 28 92 8.6E-10 T 28-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 ALX04_RS04225 f63c4d6aeb64dae33464e3f104e83f59 314 Pfam PF13602 Zinc-binding dehydrogenase 190 308 2.8E-21 T 28-03-2018 ALX04_RS04225 f63c4d6aeb64dae33464e3f104e83f59 314 Gene3D G3DSA:3.90.180.10 239 312 0.0013 T 28-03-2018 ALX04_RS04225 f63c4d6aeb64dae33464e3f104e83f59 314 Gene3D G3DSA:3.90.180.10 1 157 1.8E-52 T 28-03-2018 ALX04_RS15205 947e7dfc259007fe359ce8741f8a386b 146 Gene3D G3DSA:1.10.10.10 2 146 1.2E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS15205 947e7dfc259007fe359ce8741f8a386b 146 SUPERFAMILY SSF46785 7 142 1.13E-25 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS15205 947e7dfc259007fe359ce8741f8a386b 146 Pfam PF12802 MarR family 33 91 2.7E-8 T 28-03-2018 ALX04_RS15205 947e7dfc259007fe359ce8741f8a386b 146 SMART SM00347 27 127 5.3E-7 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 ALX04_RS13760 059b984ee4db113d046ab1c40f74a776 355 Gene3D G3DSA:3.40.50.880 136 352 1.8E-48 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like ALX04_RS13760 059b984ee4db113d046ab1c40f74a776 355 Pfam PF00117 Glutamine amidotransferase class-I 175 344 8.0E-37 T 28-03-2018 IPR017926 Glutamine amidotransferase ALX04_RS13760 059b984ee4db113d046ab1c40f74a776 355 Pfam PF00988 Carbamoyl-phosphate synthase small chain, CPSase domain 3 130 2.4E-42 T 28-03-2018 IPR002474 Carbamoyl-phosphate synthase small subunit, N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 ALX04_RS13760 059b984ee4db113d046ab1c40f74a776 355 TIGRFAM TIGR01368 CPSaseIIsmall: carbamoyl-phosphate synthase, small subunit 4 348 5.4E-128 T 28-03-2018 IPR006274 Carbamoyl-phosphate synthase, small subunit GO:0004088|GO:0006207|GO:0006541 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 ALX04_RS13760 059b984ee4db113d046ab1c40f74a776 355 PRINTS PR00097 Anthranilate synthase component II signature 209 218 2.7E-7 T 28-03-2018 ALX04_RS13760 059b984ee4db113d046ab1c40f74a776 355 PRINTS PR00097 Anthranilate synthase component II signature 236 247 2.7E-7 T 28-03-2018 ALX04_RS13760 059b984ee4db113d046ab1c40f74a776 355 PRINTS PR00097 Anthranilate synthase component II signature 322 335 2.7E-7 T 28-03-2018 ALX04_RS13760 059b984ee4db113d046ab1c40f74a776 355 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 206 220 5.4E-29 T 28-03-2018 ALX04_RS13760 059b984ee4db113d046ab1c40f74a776 355 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 278 289 5.4E-29 T 28-03-2018 ALX04_RS13760 059b984ee4db113d046ab1c40f74a776 355 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 167 181 5.4E-29 T 28-03-2018 ALX04_RS13760 059b984ee4db113d046ab1c40f74a776 355 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 253 270 5.4E-29 T 28-03-2018 ALX04_RS13760 059b984ee4db113d046ab1c40f74a776 355 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 236 252 5.4E-29 T 28-03-2018 ALX04_RS13760 059b984ee4db113d046ab1c40f74a776 355 SUPERFAMILY SSF52317 160 347 1.68E-47 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like ALX04_RS13760 059b984ee4db113d046ab1c40f74a776 355 Hamap MF_01209 Carbamoyl-phosphate synthase small chain [carA]. 1 351 41.157 T 28-03-2018 IPR006274 Carbamoyl-phosphate synthase, small subunit GO:0004088|GO:0006207|GO:0006541 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 ALX04_RS13760 059b984ee4db113d046ab1c40f74a776 355 Gene3D G3DSA:3.50.30.20 1 135 2.6E-45 T 28-03-2018 IPR002474 Carbamoyl-phosphate synthase small subunit, N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 ALX04_RS13760 059b984ee4db113d046ab1c40f74a776 355 SMART SM01097 1 132 4.5E-64 T 28-03-2018 IPR002474 Carbamoyl-phosphate synthase small subunit, N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 ALX04_RS13760 059b984ee4db113d046ab1c40f74a776 355 SUPERFAMILY SSF52021 1 140 1.16E-44 T 28-03-2018 IPR002474 Carbamoyl-phosphate synthase small subunit, N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 ALX04_RS13760 059b984ee4db113d046ab1c40f74a776 355 PRINTS PR00096 Glutamine amidotransferase superfamily signature 209 218 7.7E-12 T 28-03-2018 ALX04_RS13760 059b984ee4db113d046ab1c40f74a776 355 PRINTS PR00096 Glutamine amidotransferase superfamily signature 322 335 7.7E-12 T 28-03-2018 ALX04_RS13760 059b984ee4db113d046ab1c40f74a776 355 PRINTS PR00096 Glutamine amidotransferase superfamily signature 236 247 7.7E-12 T 28-03-2018 ALX04_RS03990 520a73b99c118a6abdd2497db19fc7e3 586 Gene3D G3DSA:3.20.20.60 1 90 1.2E-15 T 28-03-2018 ALX04_RS03990 520a73b99c118a6abdd2497db19fc7e3 586 Gene3D G3DSA:3.20.20.60 91 322 2.9E-77 T 28-03-2018 ALX04_RS03990 520a73b99c118a6abdd2497db19fc7e3 586 SUPERFAMILY SSF52935 346 546 6.41E-48 T 28-03-2018 IPR015795 Pyruvate kinase, C-terminal KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 ALX04_RS03990 520a73b99c118a6abdd2497db19fc7e3 586 TIGRFAM TIGR01064 pyruv_kin: pyruvate kinase 2 472 8.2E-170 T 28-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 ALX04_RS03990 520a73b99c118a6abdd2497db19fc7e3 586 PRINTS PR01050 Pyruvate kinase family signature 314 330 4.2E-71 T 28-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 ALX04_RS03990 520a73b99c118a6abdd2497db19fc7e3 586 PRINTS PR01050 Pyruvate kinase family signature 218 244 4.2E-71 T 28-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 ALX04_RS03990 520a73b99c118a6abdd2497db19fc7e3 586 PRINTS PR01050 Pyruvate kinase family signature 59 75 4.2E-71 T 28-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 ALX04_RS03990 520a73b99c118a6abdd2497db19fc7e3 586 PRINTS PR01050 Pyruvate kinase family signature 270 294 4.2E-71 T 28-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 ALX04_RS03990 520a73b99c118a6abdd2497db19fc7e3 586 PRINTS PR01050 Pyruvate kinase family signature 187 201 4.2E-71 T 28-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 ALX04_RS03990 520a73b99c118a6abdd2497db19fc7e3 586 PRINTS PR01050 Pyruvate kinase family signature 245 269 4.2E-71 T 28-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 ALX04_RS03990 520a73b99c118a6abdd2497db19fc7e3 586 PRINTS PR01050 Pyruvate kinase family signature 295 313 4.2E-71 T 28-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 ALX04_RS03990 520a73b99c118a6abdd2497db19fc7e3 586 Pfam PF00224 Pyruvate kinase, barrel domain 1 343 5.7E-151 T 28-03-2018 IPR015793 Pyruvate kinase, barrel GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 ALX04_RS03990 520a73b99c118a6abdd2497db19fc7e3 586 Gene3D G3DSA:3.50.30.10 472 580 1.7E-27 T 28-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 ALX04_RS03990 520a73b99c118a6abdd2497db19fc7e3 586 Pfam PF02887 Pyruvate kinase, alpha/beta domain 358 470 6.0E-34 T 28-03-2018 IPR015795 Pyruvate kinase, C-terminal KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 ALX04_RS03990 520a73b99c118a6abdd2497db19fc7e3 586 Pfam PF00391 PEP-utilising enzyme, mobile domain 507 576 2.6E-20 T 28-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 ALX04_RS03990 520a73b99c118a6abdd2497db19fc7e3 586 SUPERFAMILY SSF50800 71 168 4.01E-24 T 28-03-2018 IPR011037 Pyruvate kinase-like, insert domain ALX04_RS03990 520a73b99c118a6abdd2497db19fc7e3 586 Gene3D G3DSA:3.40.1380.20 323 471 1.1E-51 T 28-03-2018 IPR015795 Pyruvate kinase, C-terminal KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 ALX04_RS03990 520a73b99c118a6abdd2497db19fc7e3 586 SUPERFAMILY SSF51621 157 341 8.72E-95 T 28-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 ALX04_RS03990 520a73b99c118a6abdd2497db19fc7e3 586 SUPERFAMILY SSF51621 1 74 8.72E-95 T 28-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 ALX04_RS05220 5edd45fa1fbc36dae2bb7cb789eba084 574 TIGRFAM TIGR00649 MG423: beta-CASP ribonuclease, RNase J family 5 550 1.7E-165 T 28-03-2018 IPR004613 Ribonuclease J GO:0003723|GO:0046872 ALX04_RS05220 5edd45fa1fbc36dae2bb7cb789eba084 574 Hamap MF_01491 Ribonuclease J [rnj]. 1 552 39.086 T 28-03-2018 IPR030854 Ribonuclease J, bacteria GO:0004521|GO:0004534|GO:0006396|GO:0008270|GO:0090501 ALX04_RS05220 5edd45fa1fbc36dae2bb7cb789eba084 574 PIRSF PIRSF004803 1 552 5.2E-184 T 28-03-2018 IPR030854 Ribonuclease J, bacteria GO:0004521|GO:0004534|GO:0006396|GO:0008270|GO:0090501 ALX04_RS05220 5edd45fa1fbc36dae2bb7cb789eba084 574 Pfam PF00753 Metallo-beta-lactamase superfamily 17 166 2.6E-13 T 28-03-2018 IPR001279 Metallo-beta-lactamase ALX04_RS05220 5edd45fa1fbc36dae2bb7cb789eba084 574 Pfam PF07521 Zn-dependent metallo-hydrolase RNA specificity domain 351 405 1.2E-11 T 28-03-2018 IPR011108 Zn-dependent metallo-hydrolase, RNA specificity domain ALX04_RS05220 5edd45fa1fbc36dae2bb7cb789eba084 574 SMART SM00849 17 213 1.7E-21 T 28-03-2018 IPR001279 Metallo-beta-lactamase ALX04_RS05220 5edd45fa1fbc36dae2bb7cb789eba084 574 SUPERFAMILY SSF56281 5 419 4.98E-80 T 28-03-2018 IPR001279 Metallo-beta-lactamase ALX04_RS05220 5edd45fa1fbc36dae2bb7cb789eba084 574 Gene3D G3DSA:3.60.15.10 1 445 1.1E-61 T 28-03-2018 IPR001279 Metallo-beta-lactamase ALX04_RS15650 f191dbaeffe403950a298d918858f935 934 Gene3D G3DSA:3.40.50.1000 554 678 4.0E-20 T 28-03-2018 IPR023214 HAD-like domain ALX04_RS15650 f191dbaeffe403950a298d918858f935 934 SUPERFAMILY SSF81660 353 566 7.19E-45 T 28-03-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 ALX04_RS15650 f191dbaeffe403950a298d918858f935 934 Pfam PF00689 Cation transporting ATPase, C-terminus 752 918 5.1E-38 T 28-03-2018 IPR006068 Cation-transporting P-type ATPase, C-terminal Reactome: R-HSA-936837 ALX04_RS15650 f191dbaeffe403950a298d918858f935 934 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 349 355 - T 28-03-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 ALX04_RS15650 f191dbaeffe403950a298d918858f935 934 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 98 368 3.8E-32 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 ALX04_RS15650 f191dbaeffe403950a298d918858f935 934 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 626 738 4.8E-31 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 ALX04_RS15650 f191dbaeffe403950a298d918858f935 934 SUPERFAMILY SSF81653 129 237 7.85E-26 T 28-03-2018 IPR008250 P-type ATPase, A domain Reactome: R-HSA-936837 ALX04_RS15650 f191dbaeffe403950a298d918858f935 934 Pfam PF00122 E1-E2 ATPase 127 327 5.4E-46 T 28-03-2018 ALX04_RS15650 f191dbaeffe403950a298d918858f935 934 SUPERFAMILY SSF56784 345 365 4.36E-54 T 28-03-2018 IPR023214 HAD-like domain ALX04_RS15650 f191dbaeffe403950a298d918858f935 934 SUPERFAMILY SSF56784 508 770 4.36E-54 T 28-03-2018 IPR023214 HAD-like domain ALX04_RS15650 f191dbaeffe403950a298d918858f935 934 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 176 190 4.6E-38 T 28-03-2018 ALX04_RS15650 f191dbaeffe403950a298d918858f935 934 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 347 361 4.6E-38 T 28-03-2018 ALX04_RS15650 f191dbaeffe403950a298d918858f935 934 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 554 565 4.6E-38 T 28-03-2018 ALX04_RS15650 f191dbaeffe403950a298d918858f935 934 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 657 676 4.6E-38 T 28-03-2018 ALX04_RS15650 f191dbaeffe403950a298d918858f935 934 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 681 693 4.6E-38 T 28-03-2018 ALX04_RS15650 f191dbaeffe403950a298d918858f935 934 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 576 586 4.6E-38 T 28-03-2018 ALX04_RS15650 f191dbaeffe403950a298d918858f935 934 Pfam PF00690 Cation transporter/ATPase, N-terminus 9 70 5.7E-18 T 28-03-2018 IPR004014 Cation-transporting P-type ATPase, N-terminal Reactome: R-HSA-936837 ALX04_RS15650 f191dbaeffe403950a298d918858f935 934 SMART SM00831 2 76 1.7E-18 T 28-03-2018 IPR004014 Cation-transporting P-type ATPase, N-terminal Reactome: R-HSA-936837 ALX04_RS15650 f191dbaeffe403950a298d918858f935 934 Pfam PF00702 haloacid dehalogenase-like hydrolase 346 671 1.0E-24 T 28-03-2018 ALX04_RS15650 f191dbaeffe403950a298d918858f935 934 Gene3D G3DSA:1.20.1110.10 679 926 2.1E-50 T 28-03-2018 ALX04_RS15650 f191dbaeffe403950a298d918858f935 934 SUPERFAMILY SSF81665 239 341 2.62E-98 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 ALX04_RS15650 f191dbaeffe403950a298d918858f935 934 SUPERFAMILY SSF81665 707 925 2.62E-98 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 ALX04_RS15650 f191dbaeffe403950a298d918858f935 934 SUPERFAMILY SSF81665 6 129 2.62E-98 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 ALX04_RS15650 f191dbaeffe403950a298d918858f935 934 Gene3D G3DSA:2.70.150.10 11 239 1.2E-42 T 28-03-2018 ALX04_RS15650 f191dbaeffe403950a298d918858f935 934 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 689 714 3.3E-18 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 ALX04_RS15650 f191dbaeffe403950a298d918858f935 934 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 511 529 3.3E-18 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 ALX04_RS15650 f191dbaeffe403950a298d918858f935 934 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 629 645 3.3E-18 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 ALX04_RS15650 f191dbaeffe403950a298d918858f935 934 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 657 673 3.3E-18 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 ALX04_RS15650 f191dbaeffe403950a298d918858f935 934 Gene3D G3DSA:3.40.1110.10 310 553 2.9E-44 T 28-03-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 ALX04_RS08635 96f652b03bc0d3c225efcb3a0750835b 296 Gene3D G3DSA:3.40.190.10 94 195 5.7E-5 T 28-03-2018 ALX04_RS08635 96f652b03bc0d3c225efcb3a0750835b 296 SUPERFAMILY SSF46785 6 88 2.81E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS08635 96f652b03bc0d3c225efcb3a0750835b 296 Gene3D G3DSA:1.10.10.10 4 93 8.4E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS08635 96f652b03bc0d3c225efcb3a0750835b 296 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 19 30 1.2E-8 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 ALX04_RS08635 96f652b03bc0d3c225efcb3a0750835b 296 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 30 40 1.2E-8 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 ALX04_RS08635 96f652b03bc0d3c225efcb3a0750835b 296 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 40 51 1.2E-8 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 ALX04_RS08635 96f652b03bc0d3c225efcb3a0750835b 296 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 10 62 1.4E-15 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 ALX04_RS10945 e5642b0c0de3a8e2364367784f401e3a 463 Pfam PF05525 Branched-chain amino acid transport protein 12 443 6.1E-125 T 28-03-2018 IPR004685 Branched-chain amino acid transport system II carrier protein GO:0015658|GO:0015803|GO:0016021 ALX04_RS10945 e5642b0c0de3a8e2364367784f401e3a 463 TIGRFAM TIGR00796 livcs: branched-chain amino acid transport system II carrier protein 20 433 1.6E-108 T 28-03-2018 IPR004685 Branched-chain amino acid transport system II carrier protein GO:0015658|GO:0015803|GO:0016021 ALX04_RS02310 b84e98f3000f416c57dbc8b4a292c05c 274 Pfam PF06827 Zinc finger found in FPG and IleRS 245 269 2.8E-11 T 28-03-2018 IPR010663 Zinc finger, FPG/IleRS-type Reactome: R-HSA-379726 ALX04_RS02310 b84e98f3000f416c57dbc8b4a292c05c 274 Pfam PF06831 Formamidopyrimidine-DNA glycosylase H2TH domain 133 221 1.5E-26 T 28-03-2018 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 ALX04_RS02310 b84e98f3000f416c57dbc8b4a292c05c 274 Gene3D G3DSA:3.20.190.10 2 132 2.5E-43 T 28-03-2018 ALX04_RS02310 b84e98f3000f416c57dbc8b4a292c05c 274 Gene3D G3DSA:1.10.8.50 134 274 1.1E-46 T 28-03-2018 ALX04_RS02310 b84e98f3000f416c57dbc8b4a292c05c 274 TIGRFAM TIGR00577 fpg: DNA-formamidopyrimidine glycosylase 1 270 8.2E-100 T 28-03-2018 IPR020629 Formamidopyrimidine-DNA glycosylase GO:0003906|GO:0006281|GO:0008270|GO:0008534 ALX04_RS02310 b84e98f3000f416c57dbc8b4a292c05c 274 SUPERFAMILY SSF46946 133 222 8.9E-28 T 28-03-2018 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 ALX04_RS02310 b84e98f3000f416c57dbc8b4a292c05c 274 SMART SM01232 133 225 1.2E-37 T 28-03-2018 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 ALX04_RS02310 b84e98f3000f416c57dbc8b4a292c05c 274 SMART SM00898 2 117 8.8E-55 T 28-03-2018 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 ALX04_RS02310 b84e98f3000f416c57dbc8b4a292c05c 274 Hamap MF_00103 Formamidopyrimidine-DNA glycosylase [mutM]. 1 273 41.693 T 28-03-2018 IPR020629 Formamidopyrimidine-DNA glycosylase GO:0003906|GO:0006281|GO:0008270|GO:0008534 ALX04_RS02310 b84e98f3000f416c57dbc8b4a292c05c 274 SUPERFAMILY SSF57716 222 272 2.04E-16 T 28-03-2018 ALX04_RS02310 b84e98f3000f416c57dbc8b4a292c05c 274 Pfam PF01149 Formamidopyrimidine-DNA glycosylase N-terminal domain 1 116 6.7E-35 T 28-03-2018 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 ALX04_RS02310 b84e98f3000f416c57dbc8b4a292c05c 274 SUPERFAMILY SSF81624 2 140 6.28E-42 T 28-03-2018 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 ALX04_RS14715 192bef6871801c6b1840e9135149adaf 310 Hamap MF_01420 Putative sporulation transcription regulator WhiA [whiA]. 3 306 33.472 T 28-03-2018 IPR003802 Sporulation regulator WhiA GO:0043937 ALX04_RS14715 192bef6871801c6b1840e9135149adaf 310 Pfam PF02650 WhiA C-terminal HTH domain 219 303 3.9E-33 T 28-03-2018 IPR023054 Sporulation regulator WhiA, C-terminal ALX04_RS14715 192bef6871801c6b1840e9135149adaf 310 SUPERFAMILY SSF55608 119 220 6.23E-20 T 28-03-2018 IPR027434 Homing endonuclease GO:0004519 ALX04_RS14715 192bef6871801c6b1840e9135149adaf 310 Pfam PF14527 WhiA LAGLIDADG-like domain 124 216 2.9E-36 T 28-03-2018 ALX04_RS14715 192bef6871801c6b1840e9135149adaf 310 Gene3D G3DSA:3.10.28.10 14 97 9.2E-11 T 28-03-2018 IPR027434 Homing endonuclease GO:0004519 ALX04_RS14715 192bef6871801c6b1840e9135149adaf 310 Pfam PF10298 WhiA N-terminal LAGLIDADG-like domain 19 103 2.2E-34 T 28-03-2018 IPR018478 Sporulation transcription regulator WhiA, N-terminal domain ALX04_RS14715 192bef6871801c6b1840e9135149adaf 310 TIGRFAM TIGR00647 DNA_bind_WhiA: DNA-binding protein WhiA 4 304 4.8E-116 T 28-03-2018 IPR033981 Sporulation regulator WhiA-like ALX04_RS14715 192bef6871801c6b1840e9135149adaf 310 Gene3D G3DSA:3.10.28.10 113 214 8.1E-16 T 28-03-2018 IPR027434 Homing endonuclease GO:0004519 ALX04_RS05580 04b9e15e8543d200eeff4e7a5d0d20a6 170 PIRSF PIRSF029256 2 159 7.7E-59 T 28-03-2018 IPR016914 tRNA (cytidine/uridine-2'-O-)-methyltransferase GO:0001510|GO:0008168 KEGG: 00260+2.1.1.20|MetaCyc: PWY-6004 ALX04_RS05580 04b9e15e8543d200eeff4e7a5d0d20a6 170 Pfam PF00588 SpoU rRNA Methylase family 4 147 3.8E-27 T 28-03-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 ALX04_RS05580 04b9e15e8543d200eeff4e7a5d0d20a6 170 Hamap MF_01885 tRNA (cytidine(34)-2'-O)-methyltransferase [trmL]. 3 156 33.395 T 28-03-2018 IPR016914 tRNA (cytidine/uridine-2'-O-)-methyltransferase GO:0001510|GO:0008168 KEGG: 00260+2.1.1.20|MetaCyc: PWY-6004 ALX04_RS05580 04b9e15e8543d200eeff4e7a5d0d20a6 170 Gene3D G3DSA:3.40.1280.10 1 170 2.0E-34 T 28-03-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal ALX04_RS05580 04b9e15e8543d200eeff4e7a5d0d20a6 170 SUPERFAMILY SSF75217 4 158 6.54E-38 T 28-03-2018 IPR029028 Alpha/beta knot methyltransferases ALX04_RS01420 e370d8512d18a715e8766a10a53bfb5e 392 SUPERFAMILY SSF53756 2 376 8.97E-74 T 28-03-2018 ALX04_RS01420 e370d8512d18a715e8766a10a53bfb5e 392 Gene3D G3DSA:3.40.50.2000 193 350 6.9E-37 T 28-03-2018 ALX04_RS01420 e370d8512d18a715e8766a10a53bfb5e 392 Gene3D G3DSA:3.40.50.2000 11 192 2.3E-18 T 28-03-2018 ALX04_RS01420 e370d8512d18a715e8766a10a53bfb5e 392 Pfam PF00534 Glycosyl transferases group 1 194 346 1.2E-30 T 28-03-2018 IPR001296 Glycosyl transferase, family 1 ALX04_RS01420 e370d8512d18a715e8766a10a53bfb5e 392 Pfam PF13439 Glycosyltransferase Family 4 15 183 1.3E-30 T 28-03-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193 ALX04_RS02815 afb52cf9df7c92a0dc18950d0394cd9b 674 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 130 142 - T 28-03-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 ALX04_RS02815 afb52cf9df7c92a0dc18950d0394cd9b 674 Gene3D G3DSA:1.10.510.10 93 354 2.7E-55 T 28-03-2018 ALX04_RS02815 afb52cf9df7c92a0dc18950d0394cd9b 674 Pfam PF00069 Protein kinase domain 11 259 4.7E-58 T 28-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 ALX04_RS02815 afb52cf9df7c92a0dc18950d0394cd9b 674 Gene3D G3DSA:3.30.200.20 3 92 2.8E-23 T 28-03-2018 ALX04_RS02815 afb52cf9df7c92a0dc18950d0394cd9b 674 SMART SM00220 11 268 3.1E-73 T 28-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 ALX04_RS02815 afb52cf9df7c92a0dc18950d0394cd9b 674 SUPERFAMILY SSF56112 9 269 9.85E-84 T 28-03-2018 IPR011009 Protein kinase-like domain ALX04_RS02815 afb52cf9df7c92a0dc18950d0394cd9b 674 Pfam PF03793 PASTA domain 383 444 2.5E-9 T 28-03-2018 IPR005543 PASTA domain ALX04_RS02815 afb52cf9df7c92a0dc18950d0394cd9b 674 Pfam PF03793 PASTA domain 454 511 1.5E-11 T 28-03-2018 IPR005543 PASTA domain ALX04_RS02815 afb52cf9df7c92a0dc18950d0394cd9b 674 Pfam PF03793 PASTA domain 519 578 8.5E-9 T 28-03-2018 IPR005543 PASTA domain ALX04_RS02815 afb52cf9df7c92a0dc18950d0394cd9b 674 SMART SM00740 446 512 8.1E-9 T 28-03-2018 IPR005543 PASTA domain ALX04_RS02815 afb52cf9df7c92a0dc18950d0394cd9b 674 SMART SM00740 513 579 2.9E-12 T 28-03-2018 IPR005543 PASTA domain ALX04_RS02815 afb52cf9df7c92a0dc18950d0394cd9b 674 SMART SM00740 378 445 2.8E-6 T 28-03-2018 IPR005543 PASTA domain ALX04_RS02815 afb52cf9df7c92a0dc18950d0394cd9b 674 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 17 40 - T 28-03-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 ALX04_RS06015 a19fe32f6446cc20e73da25e7b50118b 880 Pfam PF01411 tRNA synthetases class II (A) 8 547 3.3E-191 T 28-03-2018 IPR018164 Alanyl-tRNA synthetase, class IIc, N-terminal GO:0000166|GO:0004813|GO:0005524|GO:0006419 KEGG: 00970+6.1.1.7 ALX04_RS06015 a19fe32f6446cc20e73da25e7b50118b 880 SUPERFAMILY SSF55681 5 245 2.36E-86 T 28-03-2018 ALX04_RS06015 a19fe32f6446cc20e73da25e7b50118b 880 SUPERFAMILY SSF50447 487 546 4.59E-12 T 28-03-2018 IPR009000 Translation protein, beta-barrel domain ALX04_RS06015 a19fe32f6446cc20e73da25e7b50118b 880 Gene3D G3DSA:3.30.930.10 3 242 2.8E-96 T 28-03-2018 ALX04_RS06015 a19fe32f6446cc20e73da25e7b50118b 880 Pfam PF07973 Threonyl and Alanyl tRNA synthetase second additional domain 657 700 5.9E-17 T 28-03-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0005524|GO:0016876|GO:0043039 ALX04_RS06015 a19fe32f6446cc20e73da25e7b50118b 880 Pfam PF02272 DHHA1 domain 738 877 5.8E-23 T 28-03-2018 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 ALX04_RS06015 a19fe32f6446cc20e73da25e7b50118b 880 Gene3D G3DSA:3.30.980.10 557 717 5.0E-41 T 28-03-2018 ALX04_RS06015 a19fe32f6446cc20e73da25e7b50118b 880 TIGRFAM TIGR00344 alaS: alanine--tRNA ligase 8 860 4.2E-294 T 28-03-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 ALX04_RS06015 a19fe32f6446cc20e73da25e7b50118b 880 SUPERFAMILY SSF55186 566 706 2.35E-44 T 28-03-2018 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain GO:0000166 ALX04_RS06015 a19fe32f6446cc20e73da25e7b50118b 880 Hamap MF_00036_B Alanine--tRNA ligase [alaS]. 1 880 169.619 T 28-03-2018 IPR023033 Alanine-tRNA ligase, eukaryota/bacteria GO:0004813 KEGG: 00970+6.1.1.7 ALX04_RS06015 a19fe32f6446cc20e73da25e7b50118b 880 PRINTS PR00980 Alanyl-tRNA synthetase signature 277 293 1.7E-30 T 28-03-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 ALX04_RS06015 a19fe32f6446cc20e73da25e7b50118b 880 PRINTS PR00980 Alanyl-tRNA synthetase signature 226 239 1.7E-30 T 28-03-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 ALX04_RS06015 a19fe32f6446cc20e73da25e7b50118b 880 PRINTS PR00980 Alanyl-tRNA synthetase signature 73 84 1.7E-30 T 28-03-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 ALX04_RS06015 a19fe32f6446cc20e73da25e7b50118b 880 PRINTS PR00980 Alanyl-tRNA synthetase signature 199 210 1.7E-30 T 28-03-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 ALX04_RS06015 a19fe32f6446cc20e73da25e7b50118b 880 PRINTS PR00980 Alanyl-tRNA synthetase signature 301 314 1.7E-30 T 28-03-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 ALX04_RS06015 a19fe32f6446cc20e73da25e7b50118b 880 SUPERFAMILY SSF101353 246 442 2.62E-61 T 28-03-2018 IPR018162 Alanine-tRNA ligase, class IIc, anti-codon-binding domain GO:0000166|GO:0004813|GO:0005524|GO:0005737|GO:0006419 KEGG: 00970+6.1.1.7 ALX04_RS06015 a19fe32f6446cc20e73da25e7b50118b 880 SMART SM00863 657 700 4.9E-20 T 28-03-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0005524|GO:0016876|GO:0043039 ALX04_RS06925 7730de49bfbe0d45dc059b583a3a7a70 129 Gene3D G3DSA:3.40.1800.10 8 129 1.3E-6 T 28-03-2018 ALX04_RS06925 7730de49bfbe0d45dc059b583a3a7a70 129 SMART SM00507 60 114 3.9E-4 T 28-03-2018 IPR003615 HNH nuclease ALX04_RS06925 7730de49bfbe0d45dc059b583a3a7a70 129 Pfam PF01844 HNH endonuclease 71 117 4.3E-8 T 28-03-2018 IPR002711 HNH endonuclease GO:0003676|GO:0004519 ALX04_RS08455 4f3b2fb9dcadc16f5eb061aa8f46c869 166 SUPERFAMILY SSF53155 16 76 3.73E-7 T 28-03-2018 IPR008332 Methylguanine DNA methyltransferase, ribonuclease-like domain GO:0003908|GO:0006281 Reactome: R-HSA-5657655 ALX04_RS08455 4f3b2fb9dcadc16f5eb061aa8f46c869 166 Gene3D G3DSA:1.10.10.10 77 163 4.2E-32 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS08455 4f3b2fb9dcadc16f5eb061aa8f46c869 166 Pfam PF01035 6-O-methylguanine DNA methyltransferase, DNA binding domain 83 161 1.4E-29 T 28-03-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 ALX04_RS08455 4f3b2fb9dcadc16f5eb061aa8f46c869 166 SUPERFAMILY SSF46767 80 162 2.75E-30 T 28-03-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 ALX04_RS08455 4f3b2fb9dcadc16f5eb061aa8f46c869 166 TIGRFAM TIGR00589 ogt: methylated-DNA--[protein]-cysteine S-methyltransferase 81 160 1.9E-33 T 28-03-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 ALX04_RS08455 4f3b2fb9dcadc16f5eb061aa8f46c869 166 Gene3D G3DSA:3.30.160.70 16 76 4.3E-9 T 28-03-2018 ALX04_RS10855 03c303eb7177d46320cc7c91faafa011 74 Pfam PF00403 Heavy-metal-associated domain 10 67 2.6E-11 T 28-03-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 ALX04_RS10855 03c303eb7177d46320cc7c91faafa011 74 SUPERFAMILY SSF55008 2 70 2.49E-17 T 28-03-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 ALX04_RS10855 03c303eb7177d46320cc7c91faafa011 74 ProSitePatterns PS01047 Heavy-metal-associated domain. 9 38 - T 28-03-2018 IPR017969 Heavy-metal-associated, conserved site GO:0030001|GO:0046872 ALX04_RS10855 03c303eb7177d46320cc7c91faafa011 74 Gene3D G3DSA:3.30.70.100 3 74 1.9E-16 T 28-03-2018 ALX04_RS12750 c8edaebea3a1577dc6e90d4fd4ffaf5d 187 Hamap MF_01984 Flavin prenyltransferase UbiX [ubiX]. 2 186 36.312 T 28-03-2018 IPR004507 Flavin prenyltransferase UbiX/Pad1 ALX04_RS12750 c8edaebea3a1577dc6e90d4fd4ffaf5d 187 Gene3D G3DSA:3.40.50.1950 2 187 1.6E-58 T 28-03-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 ALX04_RS12750 c8edaebea3a1577dc6e90d4fd4ffaf5d 187 TIGRFAM TIGR00421 ubiX_pad: polyprenyl P-hydroxybenzoate and phenylacrylic acid decarboxylases 3 184 3.0E-72 T 28-03-2018 IPR004507 Flavin prenyltransferase UbiX/Pad1 ALX04_RS12750 c8edaebea3a1577dc6e90d4fd4ffaf5d 187 Pfam PF02441 Flavoprotein 2 171 3.6E-28 T 28-03-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 ALX04_RS12750 c8edaebea3a1577dc6e90d4fd4ffaf5d 187 SUPERFAMILY SSF52507 2 186 9.03E-65 T 28-03-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 ALX04_RS09940 7310ffbe30a214ddda9f4b121ef9ae86 267 Gene3D G3DSA:3.40.190.10 166 267 2.5E-13 T 28-03-2018 ALX04_RS09940 7310ffbe30a214ddda9f4b121ef9ae86 267 ProSitePatterns PS01039 Bacterial extracellular solute-binding proteins, family 3 signature. 66 79 - T 28-03-2018 IPR018313 Solute-binding protein family 3, conserved site GO:0005215|GO:0006810 ALX04_RS09940 7310ffbe30a214ddda9f4b121ef9ae86 267 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 45 261 5.5E-60 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF ALX04_RS09940 7310ffbe30a214ddda9f4b121ef9ae86 267 Gene3D G3DSA:3.40.190.10 4 165 3.8E-35 T 28-03-2018 ALX04_RS09940 7310ffbe30a214ddda9f4b121ef9ae86 267 SMART SM00062 44 263 1.6E-63 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF ALX04_RS09940 7310ffbe30a214ddda9f4b121ef9ae86 267 SUPERFAMILY SSF53850 6 263 1.62E-61 T 28-03-2018 ALX04_RS03060 cb9d431b746e553b994f20539d157702 462 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 115 323 4.5E-71 T 28-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 ALX04_RS03060 cb9d431b746e553b994f20539d157702 462 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 153 167 - T 28-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 ALX04_RS03060 cb9d431b746e553b994f20539d157702 462 Gene3D G3DSA:3.30.470.20 210 446 3.0E-85 T 28-03-2018 ALX04_RS03060 cb9d431b746e553b994f20539d157702 462 SUPERFAMILY SSF56059 83 352 2.83E-63 T 28-03-2018 ALX04_RS03060 cb9d431b746e553b994f20539d157702 462 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 286 293 - T 28-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 ALX04_RS03060 cb9d431b746e553b994f20539d157702 462 Pfam PF00289 Biotin carboxylase, N-terminal domain 2 110 5.9E-44 T 28-03-2018 IPR005481 Biotin carboxylase-like, N-terminal domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599 ALX04_RS03060 cb9d431b746e553b994f20539d157702 462 Gene3D G3DSA:3.30.1490.20 124 209 9.4E-23 T 28-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 ALX04_RS03060 cb9d431b746e553b994f20539d157702 462 SUPERFAMILY SSF52440 2 113 1.15E-46 T 28-03-2018 IPR016185 Pre-ATP-grasp domain ALX04_RS03060 cb9d431b746e553b994f20539d157702 462 Pfam PF02785 Biotin carboxylase C-terminal domain 336 444 2.6E-32 T 28-03-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 ALX04_RS03060 cb9d431b746e553b994f20539d157702 462 SUPERFAMILY SSF51246 331 444 7.32E-35 T 28-03-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 ALX04_RS03060 cb9d431b746e553b994f20539d157702 462 SMART SM00878 336 443 4.0E-46 T 28-03-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 ALX04_RS03060 cb9d431b746e553b994f20539d157702 462 Gene3D G3DSA:3.40.50.20 1 123 3.3E-53 T 28-03-2018 ALX04_RS00390 fb752ef0bf26161c1f2bc5af50ee5b96 97 SUPERFAMILY SSF54189 1 91 6.83E-31 T 28-03-2018 IPR012678 Ribosomal protein L23/L15e core domain GO:0003735|GO:0005622|GO:0005840|GO:0006412 ALX04_RS00390 fb752ef0bf26161c1f2bc5af50ee5b96 97 ProSitePatterns PS00050 Ribosomal protein L23 signature. 76 91 - T 28-03-2018 IPR001014 Ribosomal protein L23/L25, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 ALX04_RS00390 fb752ef0bf26161c1f2bc5af50ee5b96 97 Gene3D G3DSA:3.30.70.330 1 96 1.3E-30 T 28-03-2018 ALX04_RS00390 fb752ef0bf26161c1f2bc5af50ee5b96 97 Hamap MF_01369_B 50S ribosomal protein L23 [rplW]. 4 94 21.335 T 28-03-2018 IPR013025 Ribosomal protein L25/L23 GO:0003735|GO:0005840|GO:0006412 ALX04_RS00390 fb752ef0bf26161c1f2bc5af50ee5b96 97 Pfam PF00276 Ribosomal protein L23 5 86 4.9E-30 T 28-03-2018 IPR013025 Ribosomal protein L25/L23 GO:0003735|GO:0005840|GO:0006412 ALX04_RS13445 bc0165d081d70883c0947ae815e11206 236 Pfam PF00392 Bacterial regulatory proteins, gntR family 2 62 4.8E-11 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 ALX04_RS13445 bc0165d081d70883c0947ae815e11206 236 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 22 36 5.5E-6 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 ALX04_RS13445 bc0165d081d70883c0947ae815e11206 236 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 36 52 5.5E-6 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 ALX04_RS13445 bc0165d081d70883c0947ae815e11206 236 SMART SM00866 85 224 1.5E-20 T 28-03-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 ALX04_RS13445 bc0165d081d70883c0947ae815e11206 236 SUPERFAMILY SSF64288 50 227 2.2E-34 T 28-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain ALX04_RS13445 bc0165d081d70883c0947ae815e11206 236 Pfam PF07702 UTRA domain 91 218 9.7E-26 T 28-03-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 ALX04_RS13445 bc0165d081d70883c0947ae815e11206 236 Gene3D G3DSA:3.40.1410.10 83 220 9.9E-27 T 28-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain ALX04_RS13445 bc0165d081d70883c0947ae815e11206 236 Gene3D G3DSA:1.10.10.10 1 63 1.6E-12 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS13445 bc0165d081d70883c0947ae815e11206 236 SUPERFAMILY SSF46785 2 66 1.62E-12 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS13445 bc0165d081d70883c0947ae815e11206 236 SMART SM00345 5 62 4.0E-7 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 ALX04_RS02335 db90fa9e7ad210c3536db80cb8c2d894 654 Gene3D G3DSA:3.10.20.30 1 64 1.1E-17 T 28-03-2018 IPR012675 Beta-grasp domain ALX04_RS02335 db90fa9e7ad210c3536db80cb8c2d894 654 PRINTS PR01047 Threonyl-tRNA synthetase signature 519 532 2.0E-45 T 28-03-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 ALX04_RS02335 db90fa9e7ad210c3536db80cb8c2d894 654 PRINTS PR01047 Threonyl-tRNA synthetase signature 476 504 2.0E-45 T 28-03-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 ALX04_RS02335 db90fa9e7ad210c3536db80cb8c2d894 654 PRINTS PR01047 Threonyl-tRNA synthetase signature 370 393 2.0E-45 T 28-03-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 ALX04_RS02335 db90fa9e7ad210c3536db80cb8c2d894 654 PRINTS PR01047 Threonyl-tRNA synthetase signature 337 365 2.0E-45 T 28-03-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 ALX04_RS02335 db90fa9e7ad210c3536db80cb8c2d894 654 PRINTS PR01047 Threonyl-tRNA synthetase signature 546 558 2.0E-45 T 28-03-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 ALX04_RS02335 db90fa9e7ad210c3536db80cb8c2d894 654 Gene3D G3DSA:3.30.980.10 69 233 3.4E-29 T 28-03-2018 ALX04_RS02335 db90fa9e7ad210c3536db80cb8c2d894 654 Gene3D G3DSA:3.30.930.10 234 543 1.5E-101 T 28-03-2018 ALX04_RS02335 db90fa9e7ad210c3536db80cb8c2d894 654 Pfam PF03129 Anticodon binding domain 553 641 2.7E-21 T 28-03-2018 IPR004154 Anticodon-binding ALX04_RS02335 db90fa9e7ad210c3536db80cb8c2d894 654 TIGRFAM TIGR00418 thrS: threonine--tRNA ligase 75 644 9.0E-202 T 28-03-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 ALX04_RS02335 db90fa9e7ad210c3536db80cb8c2d894 654 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 332 540 3.0E-33 T 28-03-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 ALX04_RS02335 db90fa9e7ad210c3536db80cb8c2d894 654 Gene3D G3DSA:3.40.50.800 544 654 5.1E-26 T 28-03-2018 IPR004154 Anticodon-binding ALX04_RS02335 db90fa9e7ad210c3536db80cb8c2d894 654 SMART SM00863 175 224 2.8E-17 T 28-03-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0005524|GO:0016876|GO:0043039 ALX04_RS02335 db90fa9e7ad210c3536db80cb8c2d894 654 SUPERFAMILY SSF52954 541 649 2.42E-29 T 28-03-2018 IPR004154 Anticodon-binding ALX04_RS02335 db90fa9e7ad210c3536db80cb8c2d894 654 SUPERFAMILY SSF55681 248 537 7.17E-94 T 28-03-2018 ALX04_RS02335 db90fa9e7ad210c3536db80cb8c2d894 654 Hamap MF_00184 Threonine--tRNA ligase [thrS]. 68 647 31.852 T 28-03-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 ALX04_RS02335 db90fa9e7ad210c3536db80cb8c2d894 654 Pfam PF02824 TGS domain 4 62 7.8E-9 T 28-03-2018 IPR004095 TGS KEGG: 00970+6.1.1.3 ALX04_RS02335 db90fa9e7ad210c3536db80cb8c2d894 654 SUPERFAMILY SSF81271 4 62 1.7E-13 T 28-03-2018 IPR012676 TGS-like KEGG: 00970+6.1.1.3 ALX04_RS02335 db90fa9e7ad210c3536db80cb8c2d894 654 Pfam PF07973 Threonyl and Alanyl tRNA synthetase second additional domain 175 224 1.3E-8 T 28-03-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0005524|GO:0016876|GO:0043039 ALX04_RS02335 db90fa9e7ad210c3536db80cb8c2d894 654 SUPERFAMILY SSF55186 65 245 2.75E-47 T 28-03-2018 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain GO:0000166 ALX04_RS08395 ad6d959ae002a5a61c7ae82484daffad 466 Gene3D G3DSA:1.20.200.10 130 406 1.5E-74 T 28-03-2018 ALX04_RS08395 ad6d959ae002a5a61c7ae82484daffad 466 Gene3D G3DSA:1.10.275.10 1 129 2.6E-45 T 28-03-2018 IPR024083 Fumarase/histidase, N-terminal ALX04_RS08395 ad6d959ae002a5a61c7ae82484daffad 466 ProSitePatterns PS00163 Fumarate lyases signature. 308 317 - T 28-03-2018 IPR020557 Fumarate lyase, conserved site GO:0003824 ALX04_RS08395 ad6d959ae002a5a61c7ae82484daffad 466 Pfam PF00206 Lyase 9 333 6.7E-90 T 28-03-2018 IPR022761 Fumarate lyase, N-terminal ALX04_RS08395 ad6d959ae002a5a61c7ae82484daffad 466 PRINTS PR00149 Fumarate lyase superfamily signature 126 144 7.6E-30 T 28-03-2018 IPR000362 Fumarate lyase family ALX04_RS08395 ad6d959ae002a5a61c7ae82484daffad 466 PRINTS PR00149 Fumarate lyase superfamily signature 171 189 7.6E-30 T 28-03-2018 IPR000362 Fumarate lyase family ALX04_RS08395 ad6d959ae002a5a61c7ae82484daffad 466 PRINTS PR00149 Fumarate lyase superfamily signature 262 289 7.6E-30 T 28-03-2018 IPR000362 Fumarate lyase family ALX04_RS08395 ad6d959ae002a5a61c7ae82484daffad 466 PRINTS PR00149 Fumarate lyase superfamily signature 308 324 7.6E-30 T 28-03-2018 IPR000362 Fumarate lyase family ALX04_RS08395 ad6d959ae002a5a61c7ae82484daffad 466 Gene3D G3DSA:1.10.40.30 407 456 1.9E-10 T 28-03-2018 ALX04_RS08395 ad6d959ae002a5a61c7ae82484daffad 466 SUPERFAMILY SSF48557 1 455 7.85E-125 T 28-03-2018 IPR008948 L-Aspartase-like GO:0003824 ALX04_RS08395 ad6d959ae002a5a61c7ae82484daffad 466 Pfam PF10415 Fumarase C C-terminus 400 451 9.6E-9 T 28-03-2018 IPR018951 Fumarase C, C-terminal GO:0006099|GO:0016829 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384|Reactome: R-HSA-71403 ALX04_RS10735 2f85ff61a0a733d972ca4b517fecb365 167 SMART SM00347 28 129 4.7E-10 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 ALX04_RS10735 2f85ff61a0a733d972ca4b517fecb365 167 SUPERFAMILY SSF46785 3 145 1.15E-23 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS10735 2f85ff61a0a733d972ca4b517fecb365 167 Pfam PF12802 MarR family 33 92 3.5E-9 T 28-03-2018 ALX04_RS10735 2f85ff61a0a733d972ca4b517fecb365 167 ProSitePatterns PS01117 MarR-type HTH domain signature. 67 102 - T 28-03-2018 IPR023187 Transcriptional regulator MarR-type, conserved site ALX04_RS10735 2f85ff61a0a733d972ca4b517fecb365 167 Gene3D G3DSA:1.10.10.10 2 160 1.9E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS10070 3a54ca3bb8b0146bbd4049e1c874fbf8 287 Gene3D G3DSA:3.40.50.720 124 242 3.6E-8 T 28-03-2018 ALX04_RS10070 3a54ca3bb8b0146bbd4049e1c874fbf8 287 SUPERFAMILY SSF51735 4 262 8.26E-35 T 28-03-2018 IPR016040 NAD(P)-binding domain ALX04_RS10070 3a54ca3bb8b0146bbd4049e1c874fbf8 287 Gene3D G3DSA:3.40.50.720 1 123 4.2E-8 T 28-03-2018 ALX04_RS10070 3a54ca3bb8b0146bbd4049e1c874fbf8 287 Pfam PF05368 NmrA-like family 4 226 1.5E-11 T 28-03-2018 IPR008030 NmrA-like domain Reactome: R-HSA-70635 ALX04_RS08505 2b9fc5811824ce1cd5189d92b20d2752 420 SUPERFAMILY SSF53187 9 174 2.41E-57 T 28-03-2018 ALX04_RS08505 2b9fc5811824ce1cd5189d92b20d2752 420 SUPERFAMILY SSF53187 335 419 2.41E-57 T 28-03-2018 ALX04_RS08505 2b9fc5811824ce1cd5189d92b20d2752 420 Gene3D G3DSA:3.40.630.10 4 319 3.7E-59 T 28-03-2018 ALX04_RS08505 2b9fc5811824ce1cd5189d92b20d2752 420 Pfam PF07687 Peptidase dimerisation domain 213 316 1.3E-17 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain ALX04_RS08505 2b9fc5811824ce1cd5189d92b20d2752 420 Pfam PF01546 Peptidase family M20/M25/M40 73 416 8.1E-36 T 28-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 ALX04_RS08505 2b9fc5811824ce1cd5189d92b20d2752 420 ProSitePatterns PS00758 ArgE / dapE / ACY1 / CPG2 / yscS family signature 1. 72 81 - T 28-03-2018 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 ALX04_RS08505 2b9fc5811824ce1cd5189d92b20d2752 420 SUPERFAMILY SSF55031 215 334 5.23E-20 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain ALX04_RS11095 6cd82e77feb762ecde0785123ef1079e 294 SUPERFAMILY SSF53223 4 108 3.63E-30 T 28-03-2018 ALX04_RS11095 6cd82e77feb762ecde0785123ef1079e 294 SUPERFAMILY SSF51735 109 283 1.47E-34 T 28-03-2018 IPR016040 NAD(P)-binding domain ALX04_RS11095 6cd82e77feb762ecde0785123ef1079e 294 Gene3D G3DSA:3.40.50.10860 1 119 4.0E-39 T 28-03-2018 ALX04_RS11095 6cd82e77feb762ecde0785123ef1079e 294 Pfam PF08501 Shikimate dehydrogenase substrate binding domain 14 96 1.1E-23 T 28-03-2018 IPR013708 Shikimate dehydrogenase substrate binding, N-terminal GO:0004764|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163 ALX04_RS11095 6cd82e77feb762ecde0785123ef1079e 294 Hamap MF_00222 Shikimate dehydrogenase (NADP(+)) [aroE]. 9 288 28.922 T 28-03-2018 IPR022893 Shikimate dehydrogenase family GO:0004764|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163 ALX04_RS11095 6cd82e77feb762ecde0785123ef1079e 294 Gene3D G3DSA:3.40.50.720 120 293 6.1E-31 T 28-03-2018 ALX04_RS03755 6ea78f8539107d0423494dab3791ba6b 668 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 34 176 6.5E-21 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain ALX04_RS03755 6ea78f8539107d0423494dab3791ba6b 668 SMART SM00433 37 636 0.0 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 ALX04_RS03755 6ea78f8539107d0423494dab3791ba6b 668 Pfam PF00204 DNA gyrase B 225 395 1.7E-58 T 28-03-2018 IPR013506 DNA topoisomerase, type IIA, subunit B, domain 2 GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 ALX04_RS03755 6ea78f8539107d0423494dab3791ba6b 668 SUPERFAMILY SSF56719 403 636 1.1E-82 T 28-03-2018 IPR013760 DNA topoisomerase, type IIA-like domain GO:0003918|GO:0005524 Reactome: R-HSA-4615885 ALX04_RS03755 6ea78f8539107d0423494dab3791ba6b 668 Gene3D G3DSA:3.30.230.10 225 397 1.7E-54 T 28-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup ALX04_RS03755 6ea78f8539107d0423494dab3791ba6b 668 PRINTS PR00418 DNA topoisomerase II family signature 37 52 4.8E-68 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 ALX04_RS03755 6ea78f8539107d0423494dab3791ba6b 668 PRINTS PR00418 DNA topoisomerase II family signature 493 509 4.8E-68 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 ALX04_RS03755 6ea78f8539107d0423494dab3791ba6b 668 PRINTS PR00418 DNA topoisomerase II family signature 575 591 4.8E-68 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 ALX04_RS03755 6ea78f8539107d0423494dab3791ba6b 668 PRINTS PR00418 DNA topoisomerase II family signature 427 441 4.8E-68 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 ALX04_RS03755 6ea78f8539107d0423494dab3791ba6b 668 PRINTS PR00418 DNA topoisomerase II family signature 531 543 4.8E-68 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 ALX04_RS03755 6ea78f8539107d0423494dab3791ba6b 668 PRINTS PR00418 DNA topoisomerase II family signature 72 85 4.8E-68 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 ALX04_RS03755 6ea78f8539107d0423494dab3791ba6b 668 PRINTS PR00418 DNA topoisomerase II family signature 114 128 4.8E-68 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 ALX04_RS03755 6ea78f8539107d0423494dab3791ba6b 668 PRINTS PR00418 DNA topoisomerase II family signature 271 284 4.8E-68 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 ALX04_RS03755 6ea78f8539107d0423494dab3791ba6b 668 PRINTS PR00418 DNA topoisomerase II family signature 511 528 4.8E-68 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 ALX04_RS03755 6ea78f8539107d0423494dab3791ba6b 668 TIGRFAM TIGR01058 parE_Gpos: DNA topoisomerase IV, B subunit 4 642 0.0 T 28-03-2018 IPR005740 DNA topoisomerase 4 subunit B, Firmicutes/Mollicutes GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 ALX04_RS03755 6ea78f8539107d0423494dab3791ba6b 668 Gene3D G3DSA:3.40.50.670 408 639 9.2E-94 T 28-03-2018 IPR013759 DNA topoisomerase, type IIA, central domain GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 ALX04_RS03755 6ea78f8539107d0423494dab3791ba6b 668 SMART SM00387 33 178 1.4E-26 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain ALX04_RS03755 6ea78f8539107d0423494dab3791ba6b 668 Hamap MF_00939 DNA topoisomerase 4 subunit B [parE]. 6 641 47.718 T 28-03-2018 IPR005740 DNA topoisomerase 4 subunit B, Firmicutes/Mollicutes GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 ALX04_RS03755 6ea78f8539107d0423494dab3791ba6b 668 Pfam PF01751 Toprim domain 426 533 2.4E-18 T 28-03-2018 IPR006171 TOPRIM domain ALX04_RS03755 6ea78f8539107d0423494dab3791ba6b 668 ProSitePatterns PS00177 DNA topoisomerase II signature. 429 437 - T 28-03-2018 IPR018522 DNA topoisomerase, type IIA, conserved site GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 ALX04_RS03755 6ea78f8539107d0423494dab3791ba6b 668 SUPERFAMILY SSF55874 7 216 7.73E-67 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain ALX04_RS03755 6ea78f8539107d0423494dab3791ba6b 668 SUPERFAMILY SSF54211 225 395 3.41E-53 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold ALX04_RS03755 6ea78f8539107d0423494dab3791ba6b 668 Pfam PF00986 DNA gyrase B subunit, carboxyl terminus 571 632 1.0E-29 T 28-03-2018 IPR002288 DNA gyrase B subunit, C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 ALX04_RS03755 6ea78f8539107d0423494dab3791ba6b 668 PRINTS PR01159 DNA gyrase subunit B signature 183 198 2.9E-57 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 ALX04_RS03755 6ea78f8539107d0423494dab3791ba6b 668 PRINTS PR01159 DNA gyrase subunit B signature 224 246 2.9E-57 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 ALX04_RS03755 6ea78f8539107d0423494dab3791ba6b 668 PRINTS PR01159 DNA gyrase subunit B signature 315 331 2.9E-57 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 ALX04_RS03755 6ea78f8539107d0423494dab3791ba6b 668 PRINTS PR01159 DNA gyrase subunit B signature 477 486 2.9E-57 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 ALX04_RS03755 6ea78f8539107d0423494dab3791ba6b 668 PRINTS PR01159 DNA gyrase subunit B signature 8 18 2.9E-57 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 ALX04_RS03755 6ea78f8539107d0423494dab3791ba6b 668 PRINTS PR01159 DNA gyrase subunit B signature 365 379 2.9E-57 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 ALX04_RS03755 6ea78f8539107d0423494dab3791ba6b 668 PRINTS PR01159 DNA gyrase subunit B signature 596 608 2.9E-57 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 ALX04_RS03755 6ea78f8539107d0423494dab3791ba6b 668 PRINTS PR01159 DNA gyrase subunit B signature 612 628 2.9E-57 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 ALX04_RS03755 6ea78f8539107d0423494dab3791ba6b 668 PRINTS PR01159 DNA gyrase subunit B signature 198 211 2.9E-57 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 ALX04_RS03755 6ea78f8539107d0423494dab3791ba6b 668 PRINTS PR01159 DNA gyrase subunit B signature 379 399 2.9E-57 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 ALX04_RS03755 6ea78f8539107d0423494dab3791ba6b 668 Gene3D G3DSA:3.30.565.10 20 224 1.0E-69 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain ALX04_RS14555 d264fd5ab75fe849c380a79153bc1a07 467 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 350 461 1.4E-26 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain ALX04_RS14555 d264fd5ab75fe849c380a79153bc1a07 467 SUPERFAMILY SSF55785 115 228 1.02E-5 T 28-03-2018 IPR000014 PAS domain ALX04_RS14555 d264fd5ab75fe849c380a79153bc1a07 467 Gene3D G3DSA:3.30.565.10 310 467 2.8E-43 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain ALX04_RS14555 d264fd5ab75fe849c380a79153bc1a07 467 SMART SM00387 349 462 9.9E-37 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain ALX04_RS14555 d264fd5ab75fe849c380a79153bc1a07 467 SUPERFAMILY SSF47384 224 303 6.28E-19 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 ALX04_RS14555 d264fd5ab75fe849c380a79153bc1a07 467 Gene3D G3DSA:3.30.450.20 107 232 4.5E-9 T 28-03-2018 ALX04_RS14555 d264fd5ab75fe849c380a79153bc1a07 467 Pfam PF00512 His Kinase A (phospho-acceptor) domain 237 302 7.8E-18 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 ALX04_RS14555 d264fd5ab75fe849c380a79153bc1a07 467 SUPERFAMILY SSF55874 293 460 4.71E-43 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain ALX04_RS14555 d264fd5ab75fe849c380a79153bc1a07 467 PRINTS PR00344 Bacterial sensor protein C-terminal signature 386 400 1.3E-16 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 ALX04_RS14555 d264fd5ab75fe849c380a79153bc1a07 467 PRINTS PR00344 Bacterial sensor protein C-terminal signature 422 440 1.3E-16 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 ALX04_RS14555 d264fd5ab75fe849c380a79153bc1a07 467 PRINTS PR00344 Bacterial sensor protein C-terminal signature 404 414 1.3E-16 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 ALX04_RS14555 d264fd5ab75fe849c380a79153bc1a07 467 PRINTS PR00344 Bacterial sensor protein C-terminal signature 446 459 1.3E-16 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 ALX04_RS14555 d264fd5ab75fe849c380a79153bc1a07 467 SMART SM00388 236 303 2.5E-21 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 ALX04_RS14555 d264fd5ab75fe849c380a79153bc1a07 467 Gene3D G3DSA:1.10.287.130 233 299 1.5E-17 T 28-03-2018 ALX04_RS00940 ee473c34bc29ea38cb06c69ca7fecb6a 335 Gene3D G3DSA:3.40.50.720 1 134 6.7E-26 T 28-03-2018 ALX04_RS00940 ee473c34bc29ea38cb06c69ca7fecb6a 335 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 3 115 3.3E-21 T 28-03-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 ALX04_RS00940 ee473c34bc29ea38cb06c69ca7fecb6a 335 SUPERFAMILY SSF55347 151 291 3.6E-14 T 28-03-2018 ALX04_RS00940 ee473c34bc29ea38cb06c69ca7fecb6a 335 Gene3D G3DSA:3.30.360.10 135 330 1.2E-17 T 28-03-2018 ALX04_RS00940 ee473c34bc29ea38cb06c69ca7fecb6a 335 SUPERFAMILY SSF51735 2 141 6.85E-36 T 28-03-2018 IPR016040 NAD(P)-binding domain ALX04_RS12405 90dc73f661cccf897d464f9c232383ce 304 Gene3D G3DSA:3.40.190.10 91 177 5.4E-11 T 28-03-2018 ALX04_RS12405 90dc73f661cccf897d464f9c232383ce 304 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 1.7E-6 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 ALX04_RS12405 90dc73f661cccf897d464f9c232383ce 304 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 1.7E-6 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 ALX04_RS12405 90dc73f661cccf897d464f9c232383ce 304 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 1.7E-6 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 ALX04_RS12405 90dc73f661cccf897d464f9c232383ce 304 Gene3D G3DSA:3.40.190.10 178 266 4.0E-12 T 28-03-2018 ALX04_RS12405 90dc73f661cccf897d464f9c232383ce 304 Gene3D G3DSA:1.10.10.10 1 90 5.4E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS12405 90dc73f661cccf897d464f9c232383ce 304 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 64 2.1E-15 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 ALX04_RS12405 90dc73f661cccf897d464f9c232383ce 304 Pfam PF03466 LysR substrate binding domain 88 295 1.3E-29 T 28-03-2018 IPR005119 LysR, substrate-binding ALX04_RS12405 90dc73f661cccf897d464f9c232383ce 304 SUPERFAMILY SSF53850 90 297 4.96E-28 T 28-03-2018 ALX04_RS12405 90dc73f661cccf897d464f9c232383ce 304 SUPERFAMILY SSF46785 1 89 5.85E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS14575 d30528bbc60784ee73c6a9866bbe8734 269 ProSitePatterns PS00211 ABC transporters family signature. 166 180 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 ALX04_RS14575 d30528bbc60784ee73c6a9866bbe8734 269 TIGRFAM TIGR00972 3a0107s01c2: phosphate ABC transporter, ATP-binding protein 25 269 1.4E-114 T 28-03-2018 IPR005670 Phosphate transport system permease protein 1 GO:0005315|GO:0016020|GO:0035435 ALX04_RS14575 d30528bbc60784ee73c6a9866bbe8734 269 Pfam PF00005 ABC transporter 44 193 5.0E-27 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 ALX04_RS14575 d30528bbc60784ee73c6a9866bbe8734 269 Gene3D G3DSA:3.40.50.300 11 267 2.8E-56 T 28-03-2018 ALX04_RS14575 d30528bbc60784ee73c6a9866bbe8734 269 SMART SM00382 49 250 6.9E-9 T 28-03-2018 IPR003593 AAA+ ATPase domain ALX04_RS14575 d30528bbc60784ee73c6a9866bbe8734 269 SUPERFAMILY SSF52540 18 257 1.28E-56 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase ALX04_RS11310 23b47d2d6dcc375c248d87fb20c560c5 533 SUPERFAMILY SSF53067 273 518 4.21E-11 T 28-03-2018 ALX04_RS11310 23b47d2d6dcc375c248d87fb20c560c5 533 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 277 476 1.7E-26 T 28-03-2018 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 ALX04_RS11310 23b47d2d6dcc375c248d87fb20c560c5 533 Gene3D G3DSA:3.30.420.40 264 531 3.3E-28 T 28-03-2018 ALX04_RS11310 23b47d2d6dcc375c248d87fb20c560c5 533 Gene3D G3DSA:3.30.420.40 11 263 5.0E-37 T 28-03-2018 ALX04_RS11310 23b47d2d6dcc375c248d87fb20c560c5 533 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 16 242 4.2E-17 T 28-03-2018 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 ALX04_RS11310 23b47d2d6dcc375c248d87fb20c560c5 533 SUPERFAMILY SSF53067 16 267 5.18E-28 T 28-03-2018 ALX04_RS05065 7fdb4f8bd0ee686c9d119864f39c76b4 777 Pfam PF02272 DHHA1 domain 318 440 1.2E-12 T 28-03-2018 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 ALX04_RS05065 7fdb4f8bd0ee686c9d119864f39c76b4 777 Pfam PF01368 DHH family 86 229 2.7E-11 T 28-03-2018 IPR001667 DDH domain KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 ALX04_RS05065 7fdb4f8bd0ee686c9d119864f39c76b4 777 TIGRFAM TIGR00644 recJ: single-stranded-DNA-specific exonuclease RecJ 31 563 1.3E-175 T 28-03-2018 IPR004610 Bacterial RecJ exonuclease GO:0006281|GO:0006310|GO:0008409 ALX04_RS05065 7fdb4f8bd0ee686c9d119864f39c76b4 777 Pfam PF10141 Single-strand DNA-specific exonuclease, C terminal domain 569 769 2.8E-60 T 28-03-2018 IPR018779 Single-stranded-DNA-specific exonuclease RecJ, C-terminal ALX04_RS05065 7fdb4f8bd0ee686c9d119864f39c76b4 777 SUPERFAMILY SSF64182 60 448 5.76E-111 T 28-03-2018 ALX04_RS05065 7fdb4f8bd0ee686c9d119864f39c76b4 777 Gene3D G3DSA:3.90.1640.10 63 248 1.1E-27 T 28-03-2018 ALX04_RS11160 5d24f7bde7653f0985eacd11eb906ae8 624 TIGRFAM TIGR01995 PTS-II-ABC-beta: PTS system, beta-glucoside-specific IIABC component 3 603 1.6E-225 T 28-03-2018 IPR011297 Phosphotransferase system, beta-glucoside-specific IIABC component GO:0005886|GO:0008982|GO:0009401 ALX04_RS11160 5d24f7bde7653f0985eacd11eb906ae8 624 Gene3D G3DSA:2.70.70.10 455 611 1.1E-56 T 28-03-2018 ALX04_RS11160 5d24f7bde7653f0985eacd11eb906ae8 624 SUPERFAMILY SSF51261 463 606 6.98E-55 T 28-03-2018 IPR011055 Duplicated hybrid motif ALX04_RS11160 5d24f7bde7653f0985eacd11eb906ae8 624 TIGRFAM TIGR00830 PTBA: PTS system, glucose subfamily, IIA component 468 588 2.6E-44 T 28-03-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 ALX04_RS11160 5d24f7bde7653f0985eacd11eb906ae8 624 Pfam PF00358 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 467 591 7.0E-51 T 28-03-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 ALX04_RS11160 5d24f7bde7653f0985eacd11eb906ae8 624 Pfam PF02378 Phosphotransferase system, EIIC 114 392 1.8E-33 T 28-03-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 ALX04_RS11160 5d24f7bde7653f0985eacd11eb906ae8 624 Pfam PF00367 phosphotransferase system, EIIB 8 41 1.1E-13 T 28-03-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 ALX04_RS11160 5d24f7bde7653f0985eacd11eb906ae8 624 SUPERFAMILY SSF55604 5 81 1.96E-20 T 28-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 ALX04_RS11160 5d24f7bde7653f0985eacd11eb906ae8 624 ProSitePatterns PS00371 PTS EIIA domains phosphorylation site signature 1. 530 542 - T 28-03-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 ALX04_RS11160 5d24f7bde7653f0985eacd11eb906ae8 624 Gene3D G3DSA:3.30.1360.60 2 76 1.6E-26 T 28-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 ALX04_RS02530 8808d7fabfe4ef52c27e51c51227af88 401 Gene3D G3DSA:3.30.160.60 118 146 2.0E-7 T 28-03-2018 ALX04_RS02530 8808d7fabfe4ef52c27e51c51227af88 401 Hamap MF_02065 Endolytic murein transglycosylase [mltG]. 51 394 28.881 T 28-03-2018 IPR003770 Endolytic murein transglycosylase ALX04_RS02530 8808d7fabfe4ef52c27e51c51227af88 401 TIGRFAM TIGR00247 TIGR00247: conserved hypothetical protein, YceG family 49 391 3.6E-67 T 28-03-2018 IPR003770 Endolytic murein transglycosylase ALX04_RS02530 8808d7fabfe4ef52c27e51c51227af88 401 Gene3D G3DSA:3.30.160.60 364 400 2.4E-5 T 28-03-2018 ALX04_RS02530 8808d7fabfe4ef52c27e51c51227af88 401 Pfam PF02618 YceG-like family 84 391 3.2E-68 T 28-03-2018 IPR003770 Endolytic murein transglycosylase ALX04_RS11575 77612ca27e39bdcd3d9a908bb5bfba29 379 Gene3D G3DSA:3.10.150.10 129 255 5.5E-32 T 28-03-2018 ALX04_RS11575 77612ca27e39bdcd3d9a908bb5bfba29 379 Gene3D G3DSA:3.10.150.10 1 128 2.8E-30 T 28-03-2018 ALX04_RS11575 77612ca27e39bdcd3d9a908bb5bfba29 379 TIGRFAM TIGR00663 dnan: DNA polymerase III, beta subunit 1 378 6.3E-104 T 28-03-2018 IPR001001 DNA polymerase III, beta chain GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 ALX04_RS11575 77612ca27e39bdcd3d9a908bb5bfba29 379 SUPERFAMILY SSF55979 133 250 6.91E-25 T 28-03-2018 ALX04_RS11575 77612ca27e39bdcd3d9a908bb5bfba29 379 Pfam PF02768 DNA polymerase III beta subunit, C-terminal domain 253 377 2.3E-25 T 28-03-2018 IPR022635 DNA polymerase III, beta chain, C-terminal GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 ALX04_RS11575 77612ca27e39bdcd3d9a908bb5bfba29 379 Pfam PF00712 DNA polymerase III beta subunit, N-terminal domain 1 126 2.1E-33 T 28-03-2018 IPR022634 DNA polymerase III, beta chain, N-terminal GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 ALX04_RS11575 77612ca27e39bdcd3d9a908bb5bfba29 379 Gene3D G3DSA:3.10.150.10 256 379 1.8E-22 T 28-03-2018 ALX04_RS11575 77612ca27e39bdcd3d9a908bb5bfba29 379 SMART SM00480 17 374 2.8E-128 T 28-03-2018 IPR001001 DNA polymerase III, beta chain GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 ALX04_RS11575 77612ca27e39bdcd3d9a908bb5bfba29 379 Pfam PF02767 DNA polymerase III beta subunit, central domain 136 250 6.8E-34 T 28-03-2018 IPR022637 DNA polymerase III, beta chain, central GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 ALX04_RS11575 77612ca27e39bdcd3d9a908bb5bfba29 379 SUPERFAMILY SSF55979 253 378 3.98E-27 T 28-03-2018 ALX04_RS11575 77612ca27e39bdcd3d9a908bb5bfba29 379 PIRSF PIRSF000804 1 379 2.8E-114 T 28-03-2018 IPR001001 DNA polymerase III, beta chain GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 ALX04_RS11575 77612ca27e39bdcd3d9a908bb5bfba29 379 SUPERFAMILY SSF55979 1 126 2.02E-25 T 28-03-2018 ALX04_RS16010 2dd49da3123c233e69043a3f136daaaa 391 Pfam PF00872 Transposase, Mutator family 6 362 1.1E-109 T 28-03-2018 IPR001207 Transposase, mutator type GO:0003677|GO:0004803|GO:0006313 ALX04_RS10185 60e25a58d5717b8f3a993a6774f9dcf0 432 PRINTS PR00145 Argininosuccinate lyase family signature 128 148 2.3E-7 T 28-03-2018 ALX04_RS10185 60e25a58d5717b8f3a993a6774f9dcf0 432 PRINTS PR00145 Argininosuccinate lyase family signature 261 277 2.3E-7 T 28-03-2018 ALX04_RS10185 60e25a58d5717b8f3a993a6774f9dcf0 432 PRINTS PR00145 Argininosuccinate lyase family signature 216 240 2.3E-7 T 28-03-2018 ALX04_RS10185 60e25a58d5717b8f3a993a6774f9dcf0 432 PRINTS PR00149 Fumarate lyase superfamily signature 216 243 8.1E-24 T 28-03-2018 IPR000362 Fumarate lyase family ALX04_RS10185 60e25a58d5717b8f3a993a6774f9dcf0 432 PRINTS PR00149 Fumarate lyase superfamily signature 261 277 8.1E-24 T 28-03-2018 IPR000362 Fumarate lyase family ALX04_RS10185 60e25a58d5717b8f3a993a6774f9dcf0 432 PRINTS PR00149 Fumarate lyase superfamily signature 133 151 8.1E-24 T 28-03-2018 IPR000362 Fumarate lyase family ALX04_RS10185 60e25a58d5717b8f3a993a6774f9dcf0 432 PRINTS PR00149 Fumarate lyase superfamily signature 88 106 8.1E-24 T 28-03-2018 IPR000362 Fumarate lyase family ALX04_RS10185 60e25a58d5717b8f3a993a6774f9dcf0 432 Gene3D G3DSA:1.10.275.10 2 92 1.9E-23 T 28-03-2018 IPR024083 Fumarase/histidase, N-terminal ALX04_RS10185 60e25a58d5717b8f3a993a6774f9dcf0 432 Gene3D G3DSA:1.20.200.10 93 348 8.7E-77 T 28-03-2018 ALX04_RS10185 60e25a58d5717b8f3a993a6774f9dcf0 432 Gene3D G3DSA:1.10.40.30 349 428 8.8E-23 T 28-03-2018 ALX04_RS10185 60e25a58d5717b8f3a993a6774f9dcf0 432 ProSitePatterns PS00163 Fumarate lyases signature. 261 270 - T 28-03-2018 IPR020557 Fumarate lyase, conserved site GO:0003824 ALX04_RS10185 60e25a58d5717b8f3a993a6774f9dcf0 432 Pfam PF00206 Lyase 6 286 7.3E-66 T 28-03-2018 IPR022761 Fumarate lyase, N-terminal ALX04_RS10185 60e25a58d5717b8f3a993a6774f9dcf0 432 TIGRFAM TIGR00928 purB: adenylosuccinate lyase 1 428 2.5E-164 T 28-03-2018 IPR004769 Adenylosuccinate lyase GO:0004018|GO:0009152 KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 ALX04_RS10185 60e25a58d5717b8f3a993a6774f9dcf0 432 SUPERFAMILY SSF48557 3 427 9.27E-131 T 28-03-2018 IPR008948 L-Aspartase-like GO:0003824 ALX04_RS10185 60e25a58d5717b8f3a993a6774f9dcf0 432 SMART SM00998 349 429 4.0E-37 T 28-03-2018 IPR019468 Adenylosuccinate lyase C-terminal KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 ALX04_RS10185 60e25a58d5717b8f3a993a6774f9dcf0 432 Pfam PF10397 Adenylosuccinate lyase C-terminus 350 427 1.2E-21 T 28-03-2018 IPR019468 Adenylosuccinate lyase C-terminal KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 ALX04_RS01080 5f26cf597b33b4fbf88a0ab2db16ceb8 342 Gene3D G3DSA:3.40.50.720 2 226 8.4E-50 T 28-03-2018 ALX04_RS01080 5f26cf597b33b4fbf88a0ab2db16ceb8 342 Gene3D G3DSA:3.90.25.10 227 325 3.3E-25 T 28-03-2018 ALX04_RS01080 5f26cf597b33b4fbf88a0ab2db16ceb8 342 Pfam PF16363 GDP-mannose 4,6 dehydratase 5 313 1.9E-72 T 28-03-2018 IPR016040 NAD(P)-binding domain ALX04_RS01080 5f26cf597b33b4fbf88a0ab2db16ceb8 342 TIGRFAM TIGR01181 dTDP_gluc_dehyt: dTDP-glucose 4,6-dehydratase 4 327 8.3E-133 T 28-03-2018 IPR005888 dTDP-glucose 4,6-dehydratase GO:0008460|GO:0009225 KEGG: 00521+4.2.1.46|KEGG: 00523+4.2.1.46|KEGG: 00525+4.2.1.46|MetaCyc: PWY-3221|MetaCyc: PWY-6808|MetaCyc: PWY-6942|MetaCyc: PWY-6953|MetaCyc: PWY-6973|MetaCyc: PWY-6974|MetaCyc: PWY-6976|MetaCyc: PWY-7104|MetaCyc: PWY-7301|MetaCyc: PWY-7312|MetaCyc: PWY-7315|MetaCyc: PWY-7316|MetaCyc: PWY-7318|MetaCyc: PWY-7413|MetaCyc: PWY-7414|MetaCyc: PWY-7440|MetaCyc: PWY-7657|MetaCyc: PWY-7688|MetaCyc: PWY-7814 ALX04_RS01080 5f26cf597b33b4fbf88a0ab2db16ceb8 342 SUPERFAMILY SSF51735 2 330 6.77E-91 T 28-03-2018 IPR016040 NAD(P)-binding domain ALX04_RS01925 b02866c846f88fec70b79c411a05ce51 562 Gene3D G3DSA:3.30.1360.70 1 104 1.1E-24 T 28-03-2018 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 ALX04_RS01925 b02866c846f88fec70b79c411a05ce51 562 Pfam PF05746 DALR anticodon binding domain 449 562 9.6E-32 T 28-03-2018 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 ALX04_RS01925 b02866c846f88fec70b79c411a05ce51 562 Gene3D G3DSA:1.10.730.10 430 562 2.8E-42 T 28-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 ALX04_RS01925 b02866c846f88fec70b79c411a05ce51 562 PRINTS PR01038 Arginyl-tRNA synthetase signature 296 317 6.5E-20 T 28-03-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 ALX04_RS01925 b02866c846f88fec70b79c411a05ce51 562 PRINTS PR01038 Arginyl-tRNA synthetase signature 152 165 6.5E-20 T 28-03-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 ALX04_RS01925 b02866c846f88fec70b79c411a05ce51 562 PRINTS PR01038 Arginyl-tRNA synthetase signature 113 128 6.5E-20 T 28-03-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 ALX04_RS01925 b02866c846f88fec70b79c411a05ce51 562 PRINTS PR01038 Arginyl-tRNA synthetase signature 128 144 6.5E-20 T 28-03-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 ALX04_RS01925 b02866c846f88fec70b79c411a05ce51 562 SMART SM00836 449 562 2.7E-42 T 28-03-2018 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 ALX04_RS01925 b02866c846f88fec70b79c411a05ce51 562 Pfam PF00750 tRNA synthetases class I (R) 93 434 2.2E-89 T 28-03-2018 IPR035684 Arginyl-tRNA synthetase, catalytic core domain KEGG: 00970+6.1.1.19 ALX04_RS01925 b02866c846f88fec70b79c411a05ce51 562 SMART SM01016 1 83 9.4E-24 T 28-03-2018 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 ALX04_RS01925 b02866c846f88fec70b79c411a05ce51 562 SUPERFAMILY SSF52374 109 443 2.19E-94 T 28-03-2018 ALX04_RS01925 b02866c846f88fec70b79c411a05ce51 562 TIGRFAM TIGR00456 argS: arginine--tRNA ligase 21 562 4.1E-145 T 28-03-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 ALX04_RS01925 b02866c846f88fec70b79c411a05ce51 562 SUPERFAMILY SSF55190 1 104 5.1E-24 T 28-03-2018 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 ALX04_RS01925 b02866c846f88fec70b79c411a05ce51 562 Pfam PF03485 Arginyl tRNA synthetase N terminal domain 3 83 6.4E-16 T 28-03-2018 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 ALX04_RS01925 b02866c846f88fec70b79c411a05ce51 562 SUPERFAMILY SSF47323 443 562 3.4E-32 T 28-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 ALX04_RS01925 b02866c846f88fec70b79c411a05ce51 562 Hamap MF_00123 Arginine--tRNA ligase [argS]. 5 562 25.433 T 28-03-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 ALX04_RS01925 b02866c846f88fec70b79c411a05ce51 562 Gene3D G3DSA:3.40.50.620 105 429 5.4E-58 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold ALX04_RS12960 0790c60624d6528a80091084c41eaf14 271 SUPERFAMILY SSF161098 6 253 5.51E-46 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 ALX04_RS12960 0790c60624d6528a80091084c41eaf14 271 Gene3D G3DSA:1.10.3720.10 10 266 1.0E-36 T 28-03-2018 ALX04_RS12960 0790c60624d6528a80091084c41eaf14 271 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 80 260 7.8E-15 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 ALX04_RS10520 daa0138c9cefcfdfc705f4e7027c19cf 366 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 40 173 3.6E-20 T 28-03-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 ALX04_RS10520 daa0138c9cefcfdfc705f4e7027c19cf 366 SMART SM00478 44 195 8.4E-45 T 28-03-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 ALX04_RS10520 daa0138c9cefcfdfc705f4e7027c19cf 366 Pfam PF14815 NUDIX domain 239 361 3.1E-14 T 28-03-2018 IPR029119 MutY, C-terminal Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 ALX04_RS10520 daa0138c9cefcfdfc705f4e7027c19cf 366 Gene3D G3DSA:1.10.340.30 26 122 9.1E-35 T 28-03-2018 ALX04_RS10520 daa0138c9cefcfdfc705f4e7027c19cf 366 Gene3D G3DSA:1.10.1670.10 123 229 1.2E-28 T 28-03-2018 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 ALX04_RS10520 daa0138c9cefcfdfc705f4e7027c19cf 366 SUPERFAMILY SSF48150 9 227 1.43E-68 T 28-03-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 ALX04_RS10520 daa0138c9cefcfdfc705f4e7027c19cf 366 TIGRFAM TIGR01084 mutY: A/G-specific adenine glycosylase 12 270 1.5E-89 T 28-03-2018 IPR005760 A/G-specific adenine glycosylase MutY GO:0006284|GO:0019104 ALX04_RS10520 daa0138c9cefcfdfc705f4e7027c19cf 366 SUPERFAMILY SSF55811 225 363 3.47E-14 T 28-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 ALX04_RS10520 daa0138c9cefcfdfc705f4e7027c19cf 366 Gene3D G3DSA:3.90.79.10 230 364 4.1E-8 T 28-03-2018 ALX04_RS00610 baaa84788dc00ba4fa988ee9f4d5522e 359 SUPERFAMILY SSF56796 5 341 4.71E-98 T 28-03-2018 ALX04_RS00610 baaa84788dc00ba4fa988ee9f4d5522e 359 Gene3D G3DSA:3.40.50.1970 2 173 8.5E-49 T 28-03-2018 ALX04_RS00610 baaa84788dc00ba4fa988ee9f4d5522e 359 TIGRFAM TIGR01357 aroB: 3-dehydroquinate synthase 13 340 2.4E-108 T 28-03-2018 IPR016037 3-dehydroquinate synthase AroB GO:0003856|GO:0005737|GO:0009073 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 ALX04_RS00610 baaa84788dc00ba4fa988ee9f4d5522e 359 Hamap MF_00110 3-dehydroquinate synthase [aroB]. 2 355 36.215 T 28-03-2018 IPR016037 3-dehydroquinate synthase AroB GO:0003856|GO:0005737|GO:0009073 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 ALX04_RS00610 baaa84788dc00ba4fa988ee9f4d5522e 359 Pfam PF01761 3-dehydroquinate synthase 68 322 2.1E-93 T 28-03-2018 IPR030960 3-dehydroquinate synthase domain KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 ALX04_RS00610 baaa84788dc00ba4fa988ee9f4d5522e 359 PIRSF PIRSF001455 3 354 6.7E-100 T 28-03-2018 IPR030963 3-dehydroquinate synthase family GO:0009073|GO:0016838 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 ALX04_RS00610 baaa84788dc00ba4fa988ee9f4d5522e 359 Gene3D G3DSA:1.20.1090.10 174 354 5.0E-49 T 28-03-2018 ALX04_RS09465 828fe4029d7bea868aaed08aa59ce5df 354 Pfam PF06030 Bacterial protein of unknown function (DUF916) 46 166 2.6E-40 T 28-03-2018 IPR010317 Protein of unknown function DUF916, cell surface putative ALX04_RS09465 828fe4029d7bea868aaed08aa59ce5df 354 Pfam PF11797 Protein of unknown function C-terminal (DUF3324) 179 313 1.7E-37 T 28-03-2018 IPR021759 Domain of unknown function DUF3324, C-terminal ALX04_RS09465 828fe4029d7bea868aaed08aa59ce5df 354 Gene3D G3DSA:2.60.40.1710 55 185 2.2E-10 T 28-03-2018 ALX04_RS13495 e242d701929ad3e4c4fe5dc621c29977 424 TIGRFAM TIGR00532 HMG_CoA_R_NAD: hydroxymethylglutaryl-CoA reductase, degradative 6 375 1.1E-95 T 28-03-2018 IPR004553 Hydroxymethylglutaryl-CoA reductase, bacterial-type GO:0015936|GO:0016616|GO:0050662 ALX04_RS13495 e242d701929ad3e4c4fe5dc621c29977 424 SUPERFAMILY SSF56542 220 417 7.46E-95 T 28-03-2018 IPR009029 Hydroxymethylglutaryl-CoA reductase, class I/II, substrate-binding domain GO:0015936|GO:0016616|GO:0050662|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 ALX04_RS13495 e242d701929ad3e4c4fe5dc621c29977 424 SUPERFAMILY SSF56542 5 114 7.46E-95 T 28-03-2018 IPR009029 Hydroxymethylglutaryl-CoA reductase, class I/II, substrate-binding domain GO:0015936|GO:0016616|GO:0050662|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 ALX04_RS13495 e242d701929ad3e4c4fe5dc621c29977 424 Pfam PF00368 Hydroxymethylglutaryl-coenzyme A reductase 14 375 1.4E-104 T 28-03-2018 IPR002202 Hydroxymethylglutaryl-CoA reductase, class I/II GO:0004420|GO:0015936|GO:0050662|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 ALX04_RS13495 e242d701929ad3e4c4fe5dc621c29977 424 SUPERFAMILY SSF55035 107 210 8.89E-30 T 28-03-2018 IPR009023 Hydroxymethylglutaryl-CoA reductase, class I/II, NAD/NADP-binding domain GO:0050662 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 ALX04_RS13495 e242d701929ad3e4c4fe5dc621c29977 424 Gene3D G3DSA:3.90.770.10 2 130 2.7E-22 T 28-03-2018 IPR023074 Hydroxymethylglutaryl-CoA reductase, class I/II, catalytic domain GO:0004420|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 ALX04_RS13495 e242d701929ad3e4c4fe5dc621c29977 424 Gene3D G3DSA:3.90.770.10 131 365 1.6E-50 T 28-03-2018 IPR023074 Hydroxymethylglutaryl-CoA reductase, class I/II, catalytic domain GO:0004420|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 ALX04_RS13495 e242d701929ad3e4c4fe5dc621c29977 424 ProSitePatterns PS01192 Hydroxymethylglutaryl-coenzyme A reductases signature 3. 361 374 - T 28-03-2018 IPR023076 Hydroxymethylglutaryl-CoA reductase, class I/II, conserved site GO:0004420|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 ALX04_RS13580 09247b9d1e7da4723b1c6251734c4b86 274 SUPERFAMILY SSF56601 38 271 1.65E-35 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like ALX04_RS13580 09247b9d1e7da4723b1c6251734c4b86 274 Gene3D G3DSA:3.40.710.10 31 274 9.0E-19 T 28-03-2018 ALX04_RS13580 09247b9d1e7da4723b1c6251734c4b86 274 Pfam PF13354 Beta-lactamase enzyme family 110 245 5.3E-25 T 28-03-2018 ALX04_RS08990 1387871d496485f178e46fd530e80bad 469 SUPERFAMILY SSF53474 405 465 1.75E-14 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold ALX04_RS08990 1387871d496485f178e46fd530e80bad 469 SUPERFAMILY SSF53474 75 218 1.75E-14 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold ALX04_RS08990 1387871d496485f178e46fd530e80bad 469 SUPERFAMILY SSF53474 339 371 1.75E-14 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold ALX04_RS08990 1387871d496485f178e46fd530e80bad 469 Gene3D G3DSA:3.40.50.1820 41 436 4.6E-14 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold ALX04_RS08145 e207762d814927fbd66aedb4fcf85c8e 436 Gene3D G3DSA:3.40.50.1100 221 421 1.1E-19 T 28-03-2018 ALX04_RS08145 e207762d814927fbd66aedb4fcf85c8e 436 Hamap MF_01030 D-serine dehydratase [dsdA]. 1 436 194.7 T 28-03-2018 IPR011780 D-serine ammonia-lyase GO:0008721|GO:0030170|GO:0046416 KEGG: 00260+4.3.1.18 ALX04_RS08145 e207762d814927fbd66aedb4fcf85c8e 436 Gene3D G3DSA:3.40.50.1100 86 220 1.7E-24 T 28-03-2018 ALX04_RS08145 e207762d814927fbd66aedb4fcf85c8e 436 ProSitePatterns PS00165 Serine/threonine dehydratases pyridoxal-phosphate attachment site. 101 115 - T 28-03-2018 IPR000634 Serine/threonine dehydratase, pyridoxal-phosphate-binding site GO:0006520|GO:0030170 ALX04_RS08145 e207762d814927fbd66aedb4fcf85c8e 436 TIGRFAM TIGR02035 D_Ser_am_lyase: D-serine ammonia-lyase 6 419 2.0E-153 T 28-03-2018 IPR011780 D-serine ammonia-lyase GO:0008721|GO:0030170|GO:0046416 KEGG: 00260+4.3.1.18 ALX04_RS08145 e207762d814927fbd66aedb4fcf85c8e 436 SUPERFAMILY SSF53686 34 423 9.3E-53 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme ALX04_RS08145 e207762d814927fbd66aedb4fcf85c8e 436 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 68 402 1.2E-47 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme ALX04_RS07415 721ff8f5f8282509173476494176e0dc 554 Gene3D G3DSA:2.60.40.740 164 285 8.9E-16 T 28-03-2018 ALX04_RS07415 721ff8f5f8282509173476494176e0dc 554 Gene3D G3DSA:2.60.40.1280 32 163 2.4E-19 T 28-03-2018 IPR011252 Fibrogen-binding domain 1 GO:0005618|GO:0007155 ALX04_RS07415 721ff8f5f8282509173476494176e0dc 554 SUPERFAMILY SSF49401 159 283 2.65E-20 T 28-03-2018 IPR008966 Adhesion domain ALX04_RS07415 721ff8f5f8282509173476494176e0dc 554 PRINTS PR01217 Proline rich extensin signature 319 331 2.1E-9 T 28-03-2018 ALX04_RS07415 721ff8f5f8282509173476494176e0dc 554 PRINTS PR01217 Proline rich extensin signature 342 363 2.1E-9 T 28-03-2018 ALX04_RS07415 721ff8f5f8282509173476494176e0dc 554 PRINTS PR01217 Proline rich extensin signature 363 379 2.1E-9 T 28-03-2018 ALX04_RS07415 721ff8f5f8282509173476494176e0dc 554 PRINTS PR01217 Proline rich extensin signature 292 308 2.1E-9 T 28-03-2018 ALX04_RS07415 721ff8f5f8282509173476494176e0dc 554 PRINTS PR01217 Proline rich extensin signature 382 399 2.1E-9 T 28-03-2018 ALX04_RS07415 721ff8f5f8282509173476494176e0dc 554 PRINTS PR01217 Proline rich extensin signature 406 431 2.1E-9 T 28-03-2018 ALX04_RS07415 721ff8f5f8282509173476494176e0dc 554 TIGRFAM TIGR01167 LPXTG_anchor: LPXTG cell wall anchor domain 515 550 4.8E-6 T 28-03-2018 ALX04_RS07415 721ff8f5f8282509173476494176e0dc 554 SUPERFAMILY SSF49401 37 182 6.88E-20 T 28-03-2018 IPR008966 Adhesion domain ALX04_RS02005 d754a7527bc2b3e50881b709888198c8 153 Pfam PF02863 Arginine repressor, C-terminal domain 80 145 6.8E-22 T 28-03-2018 IPR020899 Arginine repressor, C-terminal GO:0034618|GO:0051259 ALX04_RS02005 d754a7527bc2b3e50881b709888198c8 153 Gene3D G3DSA:3.30.1360.40 74 146 2.5E-23 T 28-03-2018 IPR024946 Arginine repressor C-terminal-like domain Reactome: R-HSA-4615885 ALX04_RS02005 d754a7527bc2b3e50881b709888198c8 153 ProDom PD007402 ARGININE REPRESSOR TRANSCRIPTION BIOSYNTHESIS DNA-BINDING REGULATION AMINO-ACID ARGR TRANSCRIPTIONAL FAMILY 87 130 4.0E-19 T 28-03-2018 IPR020899 Arginine repressor, C-terminal GO:0034618|GO:0051259 ALX04_RS02005 d754a7527bc2b3e50881b709888198c8 153 Gene3D G3DSA:1.10.10.10 3 66 1.4E-24 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS02005 d754a7527bc2b3e50881b709888198c8 153 Pfam PF01316 Arginine repressor, DNA binding domain 1 68 2.0E-23 T 28-03-2018 IPR020900 Arginine repressor, DNA-binding domain GO:0003700|GO:0006355|GO:0006525 ALX04_RS02005 d754a7527bc2b3e50881b709888198c8 153 TIGRFAM TIGR01529 argR_whole: arginine repressor 5 147 4.9E-43 T 28-03-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 ALX04_RS02005 d754a7527bc2b3e50881b709888198c8 153 SUPERFAMILY SSF46785 5 76 5.99E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS02005 d754a7527bc2b3e50881b709888198c8 153 Hamap MF_00173 Arginine repressor [argR]. 1 152 57.217 T 28-03-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 ALX04_RS02005 d754a7527bc2b3e50881b709888198c8 153 PRINTS PR01467 Bacterial arginine repressor signature 118 133 9.0E-18 T 28-03-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 ALX04_RS02005 d754a7527bc2b3e50881b709888198c8 153 PRINTS PR01467 Bacterial arginine repressor signature 37 52 9.0E-18 T 28-03-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 ALX04_RS02005 d754a7527bc2b3e50881b709888198c8 153 PRINTS PR01467 Bacterial arginine repressor signature 21 34 9.0E-18 T 28-03-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 ALX04_RS02005 d754a7527bc2b3e50881b709888198c8 153 PRINTS PR01467 Bacterial arginine repressor signature 88 101 9.0E-18 T 28-03-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 ALX04_RS02005 d754a7527bc2b3e50881b709888198c8 153 SUPERFAMILY SSF55252 80 148 5.23E-18 T 28-03-2018 IPR020899 Arginine repressor, C-terminal GO:0034618|GO:0051259 ALX04_RS05635 3d9b9ae637b47cbc92a1f5b8946a528f 267 Gene3D G3DSA:2.60.200.30 123 238 6.2E-26 T 28-03-2018 IPR017437 ATP-NAD kinase, PpnK-type, all-beta GO:0003951|GO:0008152|GO:0019674 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 ALX04_RS05635 3d9b9ae637b47cbc92a1f5b8946a528f 267 Hamap MF_00361 NAD kinase [nadK]. 1 263 24.039 T 28-03-2018 IPR002504 NAD kinase GO:0003951|GO:0006741|GO:0008152 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 ALX04_RS05635 3d9b9ae637b47cbc92a1f5b8946a528f 267 SUPERFAMILY SSF111331 26 261 5.36E-60 T 28-03-2018 IPR016064 NAD kinase/diacylglycerol kinase-like domain ALX04_RS05635 3d9b9ae637b47cbc92a1f5b8946a528f 267 Pfam PF01513 ATP-NAD kinase 24 219 8.0E-28 T 28-03-2018 IPR002504 NAD kinase GO:0003951|GO:0006741|GO:0008152 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 ALX04_RS05635 3d9b9ae637b47cbc92a1f5b8946a528f 267 Gene3D G3DSA:3.40.50.10330 1 122 4.9E-25 T 28-03-2018 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, domain 1 GO:0003951|GO:0008152 ALX04_RS02850 0b703737f8cfb8d37ca854f6496393bb 679 Gene3D G3DSA:2.40.50.140 45 137 5.1E-8 T 28-03-2018 ALX04_RS02850 0b703737f8cfb8d37ca854f6496393bb 679 Pfam PF00271 Helicase conserved C-terminal domain 460 570 5.9E-19 T 28-03-2018 IPR001650 Helicase, C-terminal ALX04_RS02850 0b703737f8cfb8d37ca854f6496393bb 679 Pfam PF00270 DEAD/DEAH box helicase 257 397 6.4E-17 T 28-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 ALX04_RS02850 0b703737f8cfb8d37ca854f6496393bb 679 TIGRFAM TIGR00643 recG: ATP-dependent DNA helicase RecG 26 646 1.6E-234 T 28-03-2018 IPR004609 ATP-dependent DNA helicase RecG GO:0004003|GO:0006281|GO:0006310 ALX04_RS02850 0b703737f8cfb8d37ca854f6496393bb 679 SMART SM00487 251 441 1.0E-28 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain ALX04_RS02850 0b703737f8cfb8d37ca854f6496393bb 679 SUPERFAMILY SSF52540 434 636 6.21E-43 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase ALX04_RS02850 0b703737f8cfb8d37ca854f6496393bb 679 Pfam PF17191 RecG wedge domain 12 161 1.1E-14 T 28-03-2018 IPR033454 RecG, wedge domain ALX04_RS02850 0b703737f8cfb8d37ca854f6496393bb 679 SMART SM00490 486 571 2.6E-23 T 28-03-2018 IPR001650 Helicase, C-terminal ALX04_RS02850 0b703737f8cfb8d37ca854f6496393bb 679 Gene3D G3DSA:3.40.50.300 439 611 1.4E-33 T 28-03-2018 ALX04_RS02850 0b703737f8cfb8d37ca854f6496393bb 679 SUPERFAMILY SSF50249 4 168 4.97E-27 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold ALX04_RS02850 0b703737f8cfb8d37ca854f6496393bb 679 SUPERFAMILY SSF52540 172 434 7.31E-61 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase ALX04_RS02850 0b703737f8cfb8d37ca854f6496393bb 679 Gene3D G3DSA:3.40.50.300 236 438 3.1E-37 T 28-03-2018 ALX04_RS06760 6e02cb6fa555122da5eb49285015db0d 302 Pfam PF07261 Replication initiation and membrane attachment 170 235 2.5E-9 T 28-03-2018 IPR006343 DnaD domain ALX04_RS06760 6e02cb6fa555122da5eb49285015db0d 302 TIGRFAM TIGR01446 DnaD_dom: DnaD domain protein 169 233 1.5E-8 T 28-03-2018 IPR006343 DnaD domain ALX04_RS06760 6e02cb6fa555122da5eb49285015db0d 302 SUPERFAMILY SSF158499 167 228 3.14E-6 T 28-03-2018 IPR006343 DnaD domain ALX04_RS06760 6e02cb6fa555122da5eb49285015db0d 302 Gene3D G3DSA:1.10.10.630 161 234 5.2E-14 T 28-03-2018 IPR034829 DnaD-like domain ALX04_RS07930 86498e621907de9fdbce091f0973e77e 376 SUPERFAMILY SSF52440 10 94 6.62E-26 T 28-03-2018 IPR016185 Pre-ATP-grasp domain ALX04_RS07930 86498e621907de9fdbce091f0973e77e 376 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 12 106 2.3E-6 T 28-03-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 ALX04_RS07930 86498e621907de9fdbce091f0973e77e 376 SUPERFAMILY SSF51246 311 370 3.3E-16 T 28-03-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 ALX04_RS07930 86498e621907de9fdbce091f0973e77e 376 TIGRFAM TIGR01161 purK: phosphoribosylaminoimidazole carboxylase, ATPase subunit 14 363 9.9E-116 T 28-03-2018 IPR005875 Phosphoribosylaminoimidazole carboxylase, ATPase subunit GO:0004638|GO:0006189 ALX04_RS07930 86498e621907de9fdbce091f0973e77e 376 Gene3D G3DSA:3.30.1490.20 126 187 2.3E-9 T 28-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 ALX04_RS07930 86498e621907de9fdbce091f0973e77e 376 Hamap MF_01928 N5-carboxyaminoimidazole ribonucleotide synthase [purK]. 14 362 41.74 T 28-03-2018 IPR005875 Phosphoribosylaminoimidazole carboxylase, ATPase subunit GO:0004638|GO:0006189 ALX04_RS07930 86498e621907de9fdbce091f0973e77e 376 SUPERFAMILY SSF56059 110 306 1.08E-58 T 28-03-2018 ALX04_RS07930 86498e621907de9fdbce091f0973e77e 376 Gene3D G3DSA:3.30.470.20 188 375 2.1E-40 T 28-03-2018 ALX04_RS07930 86498e621907de9fdbce091f0973e77e 376 Gene3D G3DSA:3.40.50.20 13 98 3.0E-24 T 28-03-2018 ALX04_RS07930 86498e621907de9fdbce091f0973e77e 376 Pfam PF02222 ATP-grasp domain 119 287 4.9E-48 T 28-03-2018 IPR003135 ATP-grasp fold, ATP-dependent carboxylate-amine ligase-type ALX04_RS13910 89dcb68f9aa5a836c812ab4ea06d673e 280 Gene3D G3DSA:3.60.21.10 4 273 8.6E-24 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like ALX04_RS13910 89dcb68f9aa5a836c812ab4ea06d673e 280 Pfam PF00149 Calcineurin-like phosphoesterase 8 234 4.1E-15 T 28-03-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 ALX04_RS13910 89dcb68f9aa5a836c812ab4ea06d673e 280 SUPERFAMILY SSF56300 162 259 6.53E-25 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like ALX04_RS13910 89dcb68f9aa5a836c812ab4ea06d673e 280 SUPERFAMILY SSF56300 8 131 6.53E-25 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like ALX04_RS13910 89dcb68f9aa5a836c812ab4ea06d673e 280 TIGRFAM TIGR03729 acc_ester: putative phosphoesterase 8 253 4.3E-96 T 28-03-2018 IPR022302 Phosphoesterase, putative ALX04_RS07795 2d5fdfcf28a951e684e9153e7c089e38 1200 Gene3D G3DSA:3.40.50.300 1 136 8.2E-23 T 28-03-2018 ALX04_RS07795 2d5fdfcf28a951e684e9153e7c089e38 1200 Gene3D G3DSA:3.40.50.300 137 277 9.8E-20 T 28-03-2018 ALX04_RS07795 2d5fdfcf28a951e684e9153e7c089e38 1200 Gene3D G3DSA:3.90.320.10 751 1125 2.9E-12 T 28-03-2018 IPR011604 Exonuclease, phage-type/RecB, C-terminal GO:0003677|GO:0004518 ALX04_RS07795 2d5fdfcf28a951e684e9153e7c089e38 1200 Pfam PF12705 PD-(D/E)XK nuclease superfamily 815 1146 4.0E-35 T 28-03-2018 ALX04_RS07795 2d5fdfcf28a951e684e9153e7c089e38 1200 SUPERFAMILY SSF52540 308 710 9.03E-40 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase ALX04_RS07795 2d5fdfcf28a951e684e9153e7c089e38 1200 Gene3D G3DSA:3.40.50.300 302 750 1.8E-19 T 28-03-2018 ALX04_RS07795 2d5fdfcf28a951e684e9153e7c089e38 1200 Hamap MF_01453 ATP-dependent helicase/deoxyribonuclease subunit B [rexB]. 3 1196 47.016 T 28-03-2018 IPR014141 DNA helicase subunit RexB GO:0016788|GO:0016817 ALX04_RS14515 3e844bd9ade83d9e611a963e1406473a 215 SUPERFAMILY SSF54211 3 131 4.55E-42 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold ALX04_RS14515 3e844bd9ade83d9e611a963e1406473a 215 Gene3D G3DSA:3.30.70.240 135 198 1.9E-12 T 28-03-2018 ALX04_RS14515 3e844bd9ade83d9e611a963e1406473a 215 SUPERFAMILY SSF54980 135 201 5.04E-9 T 28-03-2018 IPR035647 EF-G domain III/V-like ALX04_RS14515 3e844bd9ade83d9e611a963e1406473a 215 TIGRFAM TIGR00257 IMPACT_YIGZ: uncharacterized protein, YigZ family 4 198 6.9E-55 T 28-03-2018 IPR015796 Impact family, bacterial/archaeal ALX04_RS14515 3e844bd9ade83d9e611a963e1406473a 215 Pfam PF09186 Domain of unknown function (DUF1949) 140 195 3.7E-10 T 28-03-2018 IPR015269 Uncharacterised domain UPF0029, Impact, C-terminal ALX04_RS14515 3e844bd9ade83d9e611a963e1406473a 215 Gene3D G3DSA:3.30.230.30 4 133 5.9E-43 T 28-03-2018 IPR001498 Impact, N-terminal ALX04_RS14515 3e844bd9ade83d9e611a963e1406473a 215 Pfam PF01205 Uncharacterized protein family UPF0029 19 123 1.4E-30 T 28-03-2018 IPR001498 Impact, N-terminal ALX04_RS14515 3e844bd9ade83d9e611a963e1406473a 215 ProSitePatterns PS00910 Uncharacterized protein family UPF0029 signature. 79 108 - T 28-03-2018 IPR020569 Uncharacterised protein family UPF0029, Impact, conserved site ALX04_RS11720 9b4deecfebec914c5b1dc745a2faac62 624 PRINTS PR00344 Bacterial sensor protein C-terminal signature 536 550 1.3E-19 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 ALX04_RS11720 9b4deecfebec914c5b1dc745a2faac62 624 PRINTS PR00344 Bacterial sensor protein C-terminal signature 554 564 1.3E-19 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 ALX04_RS11720 9b4deecfebec914c5b1dc745a2faac62 624 PRINTS PR00344 Bacterial sensor protein C-terminal signature 595 608 1.3E-19 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 ALX04_RS11720 9b4deecfebec914c5b1dc745a2faac62 624 PRINTS PR00344 Bacterial sensor protein C-terminal signature 571 589 1.3E-19 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 ALX04_RS11720 9b4deecfebec914c5b1dc745a2faac62 624 Gene3D G3DSA:3.30.565.10 475 624 9.2E-43 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain ALX04_RS11720 9b4deecfebec914c5b1dc745a2faac62 624 Gene3D G3DSA:1.10.287.130 378 444 1.1E-16 T 28-03-2018 ALX04_RS11720 9b4deecfebec914c5b1dc745a2faac62 624 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 265 378 2.5E-6 T 28-03-2018 IPR000014 PAS domain ALX04_RS11720 9b4deecfebec914c5b1dc745a2faac62 624 SMART SM00091 268 334 3.9E-9 T 28-03-2018 IPR000014 PAS domain ALX04_RS11720 9b4deecfebec914c5b1dc745a2faac62 624 Gene3D G3DSA:3.30.450.20 37 186 1.4E-10 T 28-03-2018 ALX04_RS11720 9b4deecfebec914c5b1dc745a2faac62 624 SUPERFAMILY SSF55785 258 373 1.47E-11 T 28-03-2018 IPR000014 PAS domain ALX04_RS11720 9b4deecfebec914c5b1dc745a2faac62 624 Pfam PF00989 PAS fold 269 341 4.9E-6 T 28-03-2018 IPR013767 PAS fold GO:0006355 ALX04_RS11720 9b4deecfebec914c5b1dc745a2faac62 624 SMART SM00387 499 611 1.0E-39 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain ALX04_RS11720 9b4deecfebec914c5b1dc745a2faac62 624 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 500 610 1.0E-26 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain ALX04_RS11720 9b4deecfebec914c5b1dc745a2faac62 624 SUPERFAMILY SSF158472 209 258 1.96E-9 T 28-03-2018 ALX04_RS11720 9b4deecfebec914c5b1dc745a2faac62 624 Gene3D G3DSA:3.30.450.20 254 377 1.9E-19 T 28-03-2018 ALX04_RS11720 9b4deecfebec914c5b1dc745a2faac62 624 SUPERFAMILY SSF55874 437 614 7.99E-48 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain ALX04_RS11720 9b4deecfebec914c5b1dc745a2faac62 624 Pfam PF00512 His Kinase A (phospho-acceptor) domain 382 448 6.0E-18 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 ALX04_RS11720 9b4deecfebec914c5b1dc745a2faac62 624 SUPERFAMILY SSF103190 86 185 2.24E-7 T 28-03-2018 IPR029151 Periplasmic sensor domain-like ALX04_RS11720 9b4deecfebec914c5b1dc745a2faac62 624 SUPERFAMILY SSF47384 368 448 1.61E-19 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 ALX04_RS11720 9b4deecfebec914c5b1dc745a2faac62 624 SMART SM00304 209 261 2.6E-14 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 ALX04_RS11720 9b4deecfebec914c5b1dc745a2faac62 624 Pfam PF00672 HAMP domain 209 255 1.9E-12 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 ALX04_RS11720 9b4deecfebec914c5b1dc745a2faac62 624 SMART SM00388 381 448 2.7E-20 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 ALX04_RS08590 258837cdfd825f2aa13418af79953b27 322 SUPERFAMILY SSF51735 124 285 1.15E-34 T 28-03-2018 IPR016040 NAD(P)-binding domain ALX04_RS08590 258837cdfd825f2aa13418af79953b27 322 Gene3D G3DSA:3.90.180.10 50 136 5.7E-14 T 28-03-2018 ALX04_RS08590 258837cdfd825f2aa13418af79953b27 322 Pfam PF00107 Zinc-binding dehydrogenase 154 268 1.4E-20 T 28-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 ALX04_RS08590 258837cdfd825f2aa13418af79953b27 322 Gene3D G3DSA:3.40.50.10730 137 288 3.5E-26 T 28-03-2018 ALX04_RS08590 258837cdfd825f2aa13418af79953b27 322 Gene3D G3DSA:3.90.180.10 1 49 1.9E-9 T 28-03-2018 ALX04_RS08590 258837cdfd825f2aa13418af79953b27 322 SUPERFAMILY SSF50129 1 142 1.33E-33 T 28-03-2018 IPR011032 GroES-like ALX04_RS13370 75d35da74f20e5bc6b4117b97511b671 446 Gene3D G3DSA:3.30.565.10 294 443 4.3E-14 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain ALX04_RS13370 75d35da74f20e5bc6b4117b97511b671 446 SUPERFAMILY SSF55874 307 434 3.93E-12 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain ALX04_RS13370 75d35da74f20e5bc6b4117b97511b671 446 Gene3D G3DSA:1.10.287.130 229 291 4.4E-9 T 28-03-2018 ALX04_RS13370 75d35da74f20e5bc6b4117b97511b671 446 Pfam PF14501 GHKL domain 343 441 2.6E-14 T 28-03-2018 IPR032834 Sensor histidine kinase NatK, C-terminal domain ALX04_RS13370 75d35da74f20e5bc6b4117b97511b671 446 SMART SM00387 340 446 8.3E-4 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain ALX04_RS15380 240a1ad6dc49480a524f0d27d65b9d56 528 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 200 216 1.6E-22 T 28-03-2018 ALX04_RS15380 240a1ad6dc49480a524f0d27d65b9d56 528 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 226 240 1.6E-22 T 28-03-2018 ALX04_RS15380 240a1ad6dc49480a524f0d27d65b9d56 528 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 329 353 1.6E-22 T 28-03-2018 ALX04_RS15380 240a1ad6dc49480a524f0d27d65b9d56 528 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 294 306 1.6E-22 T 28-03-2018 ALX04_RS15380 240a1ad6dc49480a524f0d27d65b9d56 528 SUPERFAMILY SSF53335 85 509 6.79E-132 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase ALX04_RS15380 240a1ad6dc49480a524f0d27d65b9d56 528 SUPERFAMILY SSF53335 12 50 6.79E-132 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase ALX04_RS15380 240a1ad6dc49480a524f0d27d65b9d56 528 Gene3D G3DSA:3.40.50.150 198 471 3.3E-75 T 28-03-2018 ALX04_RS15380 240a1ad6dc49480a524f0d27d65b9d56 528 Pfam PF12161 HsdM N-terminal domain 13 162 1.4E-22 T 28-03-2018 IPR022749 N6 adenine-specific DNA methyltransferase, N-terminal domain ALX04_RS15380 240a1ad6dc49480a524f0d27d65b9d56 528 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 297 303 - T 28-03-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 ALX04_RS15380 240a1ad6dc49480a524f0d27d65b9d56 528 TIGRFAM TIGR00497 hsdM: type I restriction-modification system, M subunit 9 495 2.0E-143 T 28-03-2018 IPR004546 Restriction endonuclease, type I, HsdM GO:0003677|GO:0009007|GO:0009307 ALX04_RS15380 240a1ad6dc49480a524f0d27d65b9d56 528 Pfam PF02384 N-6 DNA Methylase 177 476 3.7E-108 T 28-03-2018 IPR003356 DNA methylase, adenine-specific GO:0003677|GO:0006306|GO:0008170 ALX04_RS15310 b511aaddcd23b4ff316659c5cf4ca209 834 SUPERFAMILY SSF55797 335 442 1.41E-9 T 28-03-2018 IPR014044 CAP domain ALX04_RS15310 b511aaddcd23b4ff316659c5cf4ca209 834 TIGRFAM TIGR01167 LPXTG_anchor: LPXTG cell wall anchor domain 801 832 5.5E-5 T 28-03-2018 ALX04_RS15310 b511aaddcd23b4ff316659c5cf4ca209 834 Gene3D G3DSA:1.10.287.620 20 172 2.2E-8 T 28-03-2018 ALX04_RS15310 b511aaddcd23b4ff316659c5cf4ca209 834 Gene3D G3DSA:1.10.287.620 173 319 0.0025 T 28-03-2018 ALX04_RS15310 b511aaddcd23b4ff316659c5cf4ca209 834 Gene3D G3DSA:1.10.287.620 586 775 9.1E-11 T 28-03-2018 ALX04_RS15310 b511aaddcd23b4ff316659c5cf4ca209 834 Pfam PF00188 Cysteine-rich secretory protein family 342 433 2.2E-6 T 28-03-2018 IPR014044 CAP domain ALX04_RS15310 b511aaddcd23b4ff316659c5cf4ca209 834 Gene3D G3DSA:3.40.33.10 331 476 1.4E-10 T 28-03-2018 IPR014044 CAP domain ALX04_RS15310 b511aaddcd23b4ff316659c5cf4ca209 834 SUPERFAMILY SSF57997 511 711 3.73E-7 T 28-03-2018 ALX04_RS15310 b511aaddcd23b4ff316659c5cf4ca209 834 Gene3D G3DSA:1.20.5.170 498 585 0.013 T 28-03-2018 ALX04_RS08345 576548393e93e6c914c990e334cd5c7a 432 PRINTS PR00173 Glutamate-aspartate symporter signature 5 25 2.7E-46 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 ALX04_RS08345 576548393e93e6c914c990e334cd5c7a 432 PRINTS PR00173 Glutamate-aspartate symporter signature 198 217 2.7E-46 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 ALX04_RS08345 576548393e93e6c914c990e334cd5c7a 432 PRINTS PR00173 Glutamate-aspartate symporter signature 333 352 2.7E-46 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 ALX04_RS08345 576548393e93e6c914c990e334cd5c7a 432 PRINTS PR00173 Glutamate-aspartate symporter signature 151 173 2.7E-46 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 ALX04_RS08345 576548393e93e6c914c990e334cd5c7a 432 PRINTS PR00173 Glutamate-aspartate symporter signature 298 324 2.7E-46 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 ALX04_RS08345 576548393e93e6c914c990e334cd5c7a 432 PRINTS PR00173 Glutamate-aspartate symporter signature 79 104 2.7E-46 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 ALX04_RS08345 576548393e93e6c914c990e334cd5c7a 432 PRINTS PR00173 Glutamate-aspartate symporter signature 49 69 2.7E-46 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 ALX04_RS08345 576548393e93e6c914c990e334cd5c7a 432 PRINTS PR00173 Glutamate-aspartate symporter signature 360 380 2.7E-46 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 ALX04_RS08345 576548393e93e6c914c990e334cd5c7a 432 ProSitePatterns PS00714 Sodium:dicarboxylate symporter family signature 2. 301 324 - T 28-03-2018 IPR018107 Sodium:dicarboxylate symporter, conserved site ALX04_RS08345 576548393e93e6c914c990e334cd5c7a 432 Pfam PF00375 Sodium:dicarboxylate symporter family 11 405 6.6E-123 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 ALX04_RS08345 576548393e93e6c914c990e334cd5c7a 432 Gene3D G3DSA:1.10.3860.10 3 413 8.2E-124 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 ALX04_RS08345 576548393e93e6c914c990e334cd5c7a 432 SUPERFAMILY SSF118215 11 407 8.5E-122 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 ALX04_RS12700 ec4d91e88174f49d0c9f018dff04abf2 239 SUPERFAMILY SSF46785 3 70 6.37E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS12700 ec4d91e88174f49d0c9f018dff04abf2 239 SMART SM00345 7 66 6.6E-15 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 ALX04_RS12700 ec4d91e88174f49d0c9f018dff04abf2 239 Gene3D G3DSA:1.10.10.10 1 68 3.5E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS12700 ec4d91e88174f49d0c9f018dff04abf2 239 SUPERFAMILY SSF64288 54 236 2.2E-37 T 28-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain ALX04_RS12700 ec4d91e88174f49d0c9f018dff04abf2 239 Pfam PF00392 Bacterial regulatory proteins, gntR family 7 66 3.7E-14 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 ALX04_RS12700 ec4d91e88174f49d0c9f018dff04abf2 239 SMART SM00866 88 229 4.8E-29 T 28-03-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 ALX04_RS12700 ec4d91e88174f49d0c9f018dff04abf2 239 TIGRFAM TIGR02404 trehalos_R_Bsub: trehalose operon repressor 3 236 9.2E-104 T 28-03-2018 IPR012770 Trehalose operon transcriptional repressor ALX04_RS12700 ec4d91e88174f49d0c9f018dff04abf2 239 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 40 56 2.9E-8 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 ALX04_RS12700 ec4d91e88174f49d0c9f018dff04abf2 239 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 26 40 2.9E-8 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 ALX04_RS12700 ec4d91e88174f49d0c9f018dff04abf2 239 Pfam PF07702 UTRA domain 119 228 7.6E-31 T 28-03-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 ALX04_RS12700 ec4d91e88174f49d0c9f018dff04abf2 239 Gene3D G3DSA:3.40.1410.10 76 231 5.1E-33 T 28-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain ALX04_RS10940 2870939fd7e1a9b756f0f115700c2c8e 578 Gene3D G3DSA:3.90.1200.10 220 391 7.1E-6 T 28-03-2018 ALX04_RS10940 2870939fd7e1a9b756f0f115700c2c8e 578 Gene3D G3DSA:3.30.200.20 90 219 4.5E-21 T 28-03-2018 ALX04_RS10940 2870939fd7e1a9b756f0f115700c2c8e 578 Pfam PF03109 ABC1 family 101 218 4.0E-29 T 28-03-2018 IPR004147 UbiB domain ALX04_RS10940 2870939fd7e1a9b756f0f115700c2c8e 578 SUPERFAMILY SSF56112 83 146 1.19E-21 T 28-03-2018 IPR011009 Protein kinase-like domain ALX04_RS10940 2870939fd7e1a9b756f0f115700c2c8e 578 SUPERFAMILY SSF56112 181 293 1.19E-21 T 28-03-2018 IPR011009 Protein kinase-like domain ALX04_RS05540 dd37b5ad51d8405f4e463d0f09c63ac8 713 SUPERFAMILY SSF56519 66 250 1.03E-35 T 28-03-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 ALX04_RS05540 dd37b5ad51d8405f4e463d0f09c63ac8 713 Gene3D G3DSA:3.90.1310.10 34 247 2.7E-29 T 28-03-2018 ALX04_RS05540 dd37b5ad51d8405f4e463d0f09c63ac8 713 SUPERFAMILY SSF56601 207 600 5.27E-86 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like ALX04_RS05540 dd37b5ad51d8405f4e463d0f09c63ac8 713 Pfam PF03717 Penicillin-binding Protein dimerisation domain 68 231 2.1E-21 T 28-03-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 ALX04_RS05540 dd37b5ad51d8405f4e463d0f09c63ac8 713 SMART SM00740 597 655 5.8E-10 T 28-03-2018 IPR005543 PASTA domain ALX04_RS05540 dd37b5ad51d8405f4e463d0f09c63ac8 713 SMART SM00740 656 713 0.074 T 28-03-2018 IPR005543 PASTA domain ALX04_RS05540 dd37b5ad51d8405f4e463d0f09c63ac8 713 SUPERFAMILY SSF54184 598 656 1.7E-13 T 28-03-2018 ALX04_RS05540 dd37b5ad51d8405f4e463d0f09c63ac8 713 SUPERFAMILY SSF54184 659 712 9.16E-12 T 28-03-2018 ALX04_RS05540 dd37b5ad51d8405f4e463d0f09c63ac8 713 Pfam PF00905 Penicillin binding protein transpeptidase domain 277 584 4.3E-78 T 28-03-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 ALX04_RS05540 dd37b5ad51d8405f4e463d0f09c63ac8 713 Pfam PF03793 PASTA domain 660 712 2.1E-6 T 28-03-2018 IPR005543 PASTA domain ALX04_RS05540 dd37b5ad51d8405f4e463d0f09c63ac8 713 Pfam PF03793 PASTA domain 601 656 1.2E-9 T 28-03-2018 IPR005543 PASTA domain ALX04_RS05540 dd37b5ad51d8405f4e463d0f09c63ac8 713 Gene3D G3DSA:3.40.710.10 248 594 1.5E-79 T 28-03-2018 ALX04_RS14675 d63d934c48597a450a601bc9082dde66 667 SMART SM00490 464 550 3.5E-21 T 28-03-2018 IPR001650 Helicase, C-terminal ALX04_RS14675 d63d934c48597a450a601bc9082dde66 667 Pfam PF04851 Type III restriction enzyme, res subunit 18 140 1.9E-10 T 28-03-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 ALX04_RS14675 d63d934c48597a450a601bc9082dde66 667 Hamap MF_00204 UvrABC system protein B [uvrB]. 8 665 43.686 T 28-03-2018 IPR004807 UvrABC system, subunit B GO:0003677|GO:0005524|GO:0006281|GO:0006289|GO:0009381|GO:0009432 ALX04_RS14675 d63d934c48597a450a601bc9082dde66 667 Pfam PF02151 UvrB/uvrC motif 632 665 3.0E-9 T 28-03-2018 IPR001943 UVR domain GO:0005515 ALX04_RS14675 d63d934c48597a450a601bc9082dde66 667 SMART SM00487 14 430 2.3E-29 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain ALX04_RS14675 d63d934c48597a450a601bc9082dde66 667 Gene3D G3DSA:3.40.50.300 16 419 1.6E-34 T 28-03-2018 ALX04_RS14675 d63d934c48597a450a601bc9082dde66 667 SUPERFAMILY SSF52540 38 85 5.74E-39 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase ALX04_RS14675 d63d934c48597a450a601bc9082dde66 667 SUPERFAMILY SSF52540 474 596 5.74E-39 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase ALX04_RS14675 d63d934c48597a450a601bc9082dde66 667 SUPERFAMILY SSF46600 620 665 2.09E-10 T 28-03-2018 IPR001943 UVR domain GO:0005515 ALX04_RS14675 d63d934c48597a450a601bc9082dde66 667 Pfam PF00271 Helicase conserved C-terminal domain 442 549 9.0E-19 T 28-03-2018 IPR001650 Helicase, C-terminal ALX04_RS14675 d63d934c48597a450a601bc9082dde66 667 SUPERFAMILY SSF52540 8 419 5.22E-142 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase ALX04_RS14675 d63d934c48597a450a601bc9082dde66 667 Pfam PF12344 Ultra-violet resistance protein B 556 597 1.2E-21 T 28-03-2018 IPR024759 UvrB, YAD/RRR-motif-containing domain ALX04_RS14675 d63d934c48597a450a601bc9082dde66 667 Gene3D G3DSA:4.10.860.10 602 667 1.7E-12 T 28-03-2018 IPR001943 UVR domain GO:0005515 ALX04_RS14675 d63d934c48597a450a601bc9082dde66 667 Gene3D G3DSA:3.40.50.300 420 593 7.9E-32 T 28-03-2018 ALX04_RS14675 d63d934c48597a450a601bc9082dde66 667 TIGRFAM TIGR00631 uvrb: excinuclease ABC subunit B 9 663 0.0 T 28-03-2018 IPR004807 UvrABC system, subunit B GO:0003677|GO:0005524|GO:0006281|GO:0006289|GO:0009381|GO:0009432 ALX04_RS01935 f2992386f5b9ef4c13876cdb78600a8f 664 ProSitePatterns PS00211 ABC transporters family signature. 144 158 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 ALX04_RS01935 f2992386f5b9ef4c13876cdb78600a8f 664 Pfam PF02687 FtsX-like permease family 563 657 6.3E-18 T 28-03-2018 IPR003838 ABC transporter permease protein domain GO:0016020 ALX04_RS01935 f2992386f5b9ef4c13876cdb78600a8f 664 Pfam PF12704 MacB-like periplasmic core domain 266 504 1.3E-8 T 28-03-2018 IPR025857 MacB-like periplasmic core domain ALX04_RS01935 f2992386f5b9ef4c13876cdb78600a8f 664 SUPERFAMILY SSF52540 4 227 3.87E-62 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase ALX04_RS01935 f2992386f5b9ef4c13876cdb78600a8f 664 SMART SM00382 32 221 3.8E-12 T 28-03-2018 IPR003593 AAA+ ATPase domain ALX04_RS01935 f2992386f5b9ef4c13876cdb78600a8f 664 Pfam PF00005 ABC transporter 23 171 1.4E-31 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 ALX04_RS01935 f2992386f5b9ef4c13876cdb78600a8f 664 Gene3D G3DSA:3.40.50.300 1 243 8.0E-63 T 28-03-2018 ALX04_RS03615 fb25b51acf2530f37e561fcd76e67e59 395 SUPERFAMILY SSF103473 10 392 3.66E-42 T 28-03-2018 IPR020846 Major facilitator superfamily domain ALX04_RS03615 fb25b51acf2530f37e561fcd76e67e59 395 Gene3D G3DSA:1.20.1250.20 2 200 2.3E-21 T 28-03-2018 ALX04_RS03615 fb25b51acf2530f37e561fcd76e67e59 395 Gene3D G3DSA:1.20.1250.20 203 395 9.1E-16 T 28-03-2018 ALX04_RS03615 fb25b51acf2530f37e561fcd76e67e59 395 Pfam PF07690 Major Facilitator Superfamily 16 351 7.5E-21 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 ALX04_RS04410 38f6fd7cb9d9f7a4ce3f862cee2bec78 176 SUPERFAMILY SSF55068 1 152 2.88E-65 T 28-03-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 ALX04_RS04410 38f6fd7cb9d9f7a4ce3f862cee2bec78 176 TIGRFAM TIGR00401 msrA: peptide-methionine (S)-S-oxide reductase 2 151 1.7E-56 T 28-03-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 ALX04_RS04410 38f6fd7cb9d9f7a4ce3f862cee2bec78 176 Gene3D G3DSA:3.30.1060.10 1 166 3.8E-61 T 28-03-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 ALX04_RS04410 38f6fd7cb9d9f7a4ce3f862cee2bec78 176 Pfam PF01625 Peptide methionine sulfoxide reductase 3 151 4.2E-56 T 28-03-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 ALX04_RS04410 38f6fd7cb9d9f7a4ce3f862cee2bec78 176 Hamap MF_01401 Peptide methionine sulfoxide reductase MsrA [msrA]. 1 160 33.8 T 28-03-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 ALX04_RS12955 0078369f37e084915495ff0f63e66822 356 PIRSF PIRSF019574 1 356 1.3E-126 T 28-03-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 ALX04_RS12955 0078369f37e084915495ff0f63e66822 356 Gene3D G3DSA:3.40.190.10 32 151 4.6E-22 T 28-03-2018 ALX04_RS12955 0078369f37e084915495ff0f63e66822 356 Pfam PF13416 Bacterial extracellular solute-binding protein 51 318 1.7E-32 T 28-03-2018 ALX04_RS12955 0078369f37e084915495ff0f63e66822 356 SUPERFAMILY SSF53850 34 353 7.83E-89 T 28-03-2018 ALX04_RS12955 0078369f37e084915495ff0f63e66822 356 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 300 326 5.6E-55 T 28-03-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 ALX04_RS12955 0078369f37e084915495ff0f63e66822 356 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 40 56 5.6E-55 T 28-03-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 ALX04_RS12955 0078369f37e084915495ff0f63e66822 356 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 56 77 5.6E-55 T 28-03-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 ALX04_RS12955 0078369f37e084915495ff0f63e66822 356 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 130 146 5.6E-55 T 28-03-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 ALX04_RS12955 0078369f37e084915495ff0f63e66822 356 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 211 230 5.6E-55 T 28-03-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 ALX04_RS12955 0078369f37e084915495ff0f63e66822 356 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 99 112 5.6E-55 T 28-03-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 ALX04_RS12955 0078369f37e084915495ff0f63e66822 356 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 156 170 5.6E-55 T 28-03-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 ALX04_RS12955 0078369f37e084915495ff0f63e66822 356 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 255 274 5.6E-55 T 28-03-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 ALX04_RS12955 0078369f37e084915495ff0f63e66822 356 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 174 193 5.6E-55 T 28-03-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 ALX04_RS12955 0078369f37e084915495ff0f63e66822 356 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 83 97 5.6E-55 T 28-03-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 ALX04_RS12955 0078369f37e084915495ff0f63e66822 356 Gene3D G3DSA:3.40.190.10 152 307 1.7E-35 T 28-03-2018 ALX04_RS05505 0b54914d64fd7d3b8d86557ee2881f26 140 Hamap MF_01197 Cell division protein SepF [sepF]. 1 135 17.74 T 28-03-2018 IPR023052 Cell division protein SepF GO:0090529 ALX04_RS05505 0b54914d64fd7d3b8d86557ee2881f26 140 Pfam PF04472 Cell division protein SepF 56 127 3.7E-25 T 28-03-2018 IPR007561 Cell division protein SepF/SepF-related GO:0090529 ALX04_RS08405 9ea60fe454dfd42432d83a293b36521b 220 Gene3D G3DSA:3.40.50.1000 4 220 7.3E-19 T 28-03-2018 IPR023214 HAD-like domain ALX04_RS08405 9ea60fe454dfd42432d83a293b36521b 220 Pfam PF13419 Haloacid dehalogenase-like hydrolase 8 170 8.2E-9 T 28-03-2018 IPR023214 HAD-like domain ALX04_RS08405 9ea60fe454dfd42432d83a293b36521b 220 SUPERFAMILY SSF56784 4 219 3.92E-33 T 28-03-2018 IPR023214 HAD-like domain ALX04_RS09565 fc837897bdd36e121f278b4ef5091f4c 470 Pfam PF00171 Aldehyde dehydrogenase family 3 451 5.1E-128 T 28-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 ALX04_RS09565 fc837897bdd36e121f278b4ef5091f4c 470 Gene3D G3DSA:3.40.309.10 244 438 1.4E-63 T 28-03-2018 ALX04_RS09565 fc837897bdd36e121f278b4ef5091f4c 470 SUPERFAMILY SSF53720 3 454 2.23E-134 T 28-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 ALX04_RS09565 fc837897bdd36e121f278b4ef5091f4c 470 Gene3D G3DSA:3.40.605.10 1 243 2.1E-63 T 28-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 ALX04_RS07820 9c7711329502cd83fe73f4ae0d2b9074 1058 Gene3D G3DSA:3.40.50.20 4 117 4.8E-37 T 28-03-2018 ALX04_RS07820 9c7711329502cd83fe73f4ae0d2b9074 1058 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 702 716 - T 28-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 ALX04_RS07820 9c7711329502cd83fe73f4ae0d2b9074 1058 Gene3D G3DSA:3.30.1490.20 648 738 2.6E-19 T 28-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 ALX04_RS07820 9c7711329502cd83fe73f4ae0d2b9074 1058 SUPERFAMILY SSF56059 666 927 6.01E-98 T 28-03-2018 ALX04_RS07820 9c7711329502cd83fe73f4ae0d2b9074 1058 SUPERFAMILY SSF56059 128 399 6.01E-106 T 28-03-2018 ALX04_RS07820 9c7711329502cd83fe73f4ae0d2b9074 1058 SMART SM01096 420 540 1.1E-59 T 28-03-2018 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 ALX04_RS07820 9c7711329502cd83fe73f4ae0d2b9074 1058 Gene3D G3DSA:1.10.1030.10 403 531 1.4E-43 T 28-03-2018 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 ALX04_RS07820 9c7711329502cd83fe73f4ae0d2b9074 1058 Gene3D G3DSA:3.40.50.20 532 647 4.7E-57 T 28-03-2018 ALX04_RS07820 9c7711329502cd83fe73f4ae0d2b9074 1058 Pfam PF02142 MGS-like domain 950 1036 5.5E-19 T 28-03-2018 IPR011607 Methylglyoxal synthase-like domain ALX04_RS07820 9c7711329502cd83fe73f4ae0d2b9074 1058 Hamap MF_01210_B Carbamoyl-phosphate synthase large chain [carB]. 1 1057 13.093 T 28-03-2018 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 ALX04_RS07820 9c7711329502cd83fe73f4ae0d2b9074 1058 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 164 178 - T 28-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 ALX04_RS07820 9c7711329502cd83fe73f4ae0d2b9074 1058 Gene3D G3DSA:3.30.470.20 739 920 1.2E-40 T 28-03-2018 ALX04_RS07820 9c7711329502cd83fe73f4ae0d2b9074 1058 Gene3D G3DSA:3.30.470.20 120 401 8.0E-68 T 28-03-2018 ALX04_RS07820 9c7711329502cd83fe73f4ae0d2b9074 1058 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 830 837 - T 28-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 ALX04_RS07820 9c7711329502cd83fe73f4ae0d2b9074 1058 SUPERFAMILY SSF52440 550 668 1.19E-46 T 28-03-2018 IPR016185 Pre-ATP-grasp domain ALX04_RS07820 9c7711329502cd83fe73f4ae0d2b9074 1058 SUPERFAMILY SSF52440 1 127 2.45E-48 T 28-03-2018 IPR016185 Pre-ATP-grasp domain ALX04_RS07820 9c7711329502cd83fe73f4ae0d2b9074 1058 SMART SM00851 949 1036 8.0E-24 T 28-03-2018 IPR011607 Methylglyoxal synthase-like domain ALX04_RS07820 9c7711329502cd83fe73f4ae0d2b9074 1058 Gene3D G3DSA:3.40.50.1380 921 1047 1.9E-32 T 28-03-2018 IPR011607 Methylglyoxal synthase-like domain ALX04_RS07820 9c7711329502cd83fe73f4ae0d2b9074 1058 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 296 325 5.6E-62 T 28-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 ALX04_RS07820 9c7711329502cd83fe73f4ae0d2b9074 1058 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 48 58 5.6E-62 T 28-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 ALX04_RS07820 9c7711329502cd83fe73f4ae0d2b9074 1058 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 19 33 5.6E-62 T 28-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 ALX04_RS07820 9c7711329502cd83fe73f4ae0d2b9074 1058 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 168 180 5.6E-62 T 28-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 ALX04_RS07820 9c7711329502cd83fe73f4ae0d2b9074 1058 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 204 223 5.6E-62 T 28-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 ALX04_RS07820 9c7711329502cd83fe73f4ae0d2b9074 1058 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 378 396 5.6E-62 T 28-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 ALX04_RS07820 9c7711329502cd83fe73f4ae0d2b9074 1058 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 239 256 5.6E-62 T 28-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 ALX04_RS07820 9c7711329502cd83fe73f4ae0d2b9074 1058 TIGRFAM TIGR01369 CPSaseII_lrg: carbamoyl-phosphate synthase, large subunit 2 1046 0.0 T 28-03-2018 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 ALX04_RS07820 9c7711329502cd83fe73f4ae0d2b9074 1058 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 296 303 - T 28-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 ALX04_RS07820 9c7711329502cd83fe73f4ae0d2b9074 1058 Pfam PF02787 Carbamoyl-phosphate synthetase large chain, oligomerisation domain 423 540 2.7E-36 T 28-03-2018 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 ALX04_RS07820 9c7711329502cd83fe73f4ae0d2b9074 1058 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 666 867 6.8E-32 T 28-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 ALX04_RS07820 9c7711329502cd83fe73f4ae0d2b9074 1058 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 128 333 4.5E-75 T 28-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 ALX04_RS07820 9c7711329502cd83fe73f4ae0d2b9074 1058 SUPERFAMILY SSF52335 931 1050 3.53E-29 T 28-03-2018 IPR011607 Methylglyoxal synthase-like domain ALX04_RS07820 9c7711329502cd83fe73f4ae0d2b9074 1058 SUPERFAMILY SSF48108 395 546 4.97E-48 T 28-03-2018 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 ALX04_RS10275 8f1a4bf1ce3401ece8ae28e02211789f 114 Pfam PF01022 Bacterial regulatory protein, arsR family 36 80 4.7E-12 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 ALX04_RS10275 8f1a4bf1ce3401ece8ae28e02211789f 114 Gene3D G3DSA:1.10.10.10 1 114 1.6E-24 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS10275 8f1a4bf1ce3401ece8ae28e02211789f 114 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 31 46 1.4E-11 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 ALX04_RS10275 8f1a4bf1ce3401ece8ae28e02211789f 114 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 63 78 1.4E-11 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 ALX04_RS10275 8f1a4bf1ce3401ece8ae28e02211789f 114 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 78 93 1.4E-11 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 ALX04_RS10275 8f1a4bf1ce3401ece8ae28e02211789f 114 SUPERFAMILY SSF46785 13 108 1.37E-24 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS10275 8f1a4bf1ce3401ece8ae28e02211789f 114 SMART SM00418 29 107 1.6E-22 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 ALX04_RS04645 a62af6b060c87e5c9811d0ad02c95906 292 ProSitePatterns PS01127 Elongation factor Ts signature 2. 75 85 - T 28-03-2018 IPR018101 Translation elongation factor Ts, conserved site GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 ALX04_RS04645 a62af6b060c87e5c9811d0ad02c95906 292 SUPERFAMILY SSF46934 4 55 2.37E-18 T 28-03-2018 IPR009060 UBA-like GO:0005515 ALX04_RS04645 a62af6b060c87e5c9811d0ad02c95906 292 Pfam PF00889 Elongation factor TS 71 273 1.2E-68 T 28-03-2018 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 ALX04_RS04645 a62af6b060c87e5c9811d0ad02c95906 292 Hamap MF_00050 Elongation factor Ts [tsf]. 1 290 74.812 T 28-03-2018 IPR001816 Translation elongation factor EFTs/EF1B GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 ALX04_RS04645 a62af6b060c87e5c9811d0ad02c95906 292 TIGRFAM TIGR00116 tsf: translation elongation factor Ts 1 291 1.2E-96 T 28-03-2018 IPR001816 Translation elongation factor EFTs/EF1B GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 ALX04_RS04645 a62af6b060c87e5c9811d0ad02c95906 292 Gene3D G3DSA:1.10.8.10 1 56 2.0E-24 T 28-03-2018 ALX04_RS04645 a62af6b060c87e5c9811d0ad02c95906 292 ProSitePatterns PS01126 Elongation factor Ts signature 1. 12 27 - T 28-03-2018 IPR018101 Translation elongation factor Ts, conserved site GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 ALX04_RS04645 a62af6b060c87e5c9811d0ad02c95906 292 Gene3D G3DSA:3.30.479.20 158 289 7.5E-46 T 28-03-2018 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 ALX04_RS04645 a62af6b060c87e5c9811d0ad02c95906 292 Gene3D G3DSA:3.30.479.20 58 157 1.7E-21 T 28-03-2018 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 ALX04_RS04645 a62af6b060c87e5c9811d0ad02c95906 292 SUPERFAMILY SSF54713 56 145 4.71E-18 T 28-03-2018 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 ALX04_RS04645 a62af6b060c87e5c9811d0ad02c95906 292 SUPERFAMILY SSF54713 152 291 2.75E-50 T 28-03-2018 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 ALX04_RS09795 d1584f8f6e489be8204c0a0935c7ba45 397 Gene3D G3DSA:3.40.50.150 101 374 1.7E-69 T 28-03-2018 ALX04_RS09795 d1584f8f6e489be8204c0a0935c7ba45 397 PIRSF PIRSF003085 5 390 4.8E-129 T 28-03-2018 IPR003333 Mycolic acid cyclopropane synthase GO:0008610 ALX04_RS09795 d1584f8f6e489be8204c0a0935c7ba45 397 Pfam PF02353 Mycolic acid cyclopropane synthetase 103 369 7.1E-100 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase ALX04_RS09795 d1584f8f6e489be8204c0a0935c7ba45 397 SUPERFAMILY SSF53335 2 329 2.43E-81 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase ALX04_RS11940 06e8b6b2bd225daa9301aed56a09a12a 287 Pfam PF00561 alpha/beta hydrolase fold 22 271 3.0E-27 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 ALX04_RS11940 06e8b6b2bd225daa9301aed56a09a12a 287 TIGRFAM TIGR01250 pro_imino_pep_2: proline-specific peptidase 2 283 6.5E-88 T 28-03-2018 IPR005945 Proline-specific peptidase GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 ALX04_RS11940 06e8b6b2bd225daa9301aed56a09a12a 287 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 51 62 3.0E-14 T 28-03-2018 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 ALX04_RS11940 06e8b6b2bd225daa9301aed56a09a12a 287 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 94 108 3.0E-14 T 28-03-2018 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 ALX04_RS11940 06e8b6b2bd225daa9301aed56a09a12a 287 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 23 31 3.0E-14 T 28-03-2018 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 ALX04_RS11940 06e8b6b2bd225daa9301aed56a09a12a 287 PIRSF PIRSF005539 1 287 1.4E-106 T 28-03-2018 IPR005945 Proline-specific peptidase GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 ALX04_RS11940 06e8b6b2bd225daa9301aed56a09a12a 287 Gene3D G3DSA:3.40.50.1820 1 287 5.4E-45 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold ALX04_RS11940 06e8b6b2bd225daa9301aed56a09a12a 287 SUPERFAMILY SSF53474 3 283 1.59E-51 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold ALX04_RS03260 c9b89f4f568430813591f62d38d932c5 449 SUPERFAMILY SSF53383 23 432 1.02E-125 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase ALX04_RS03260 c9b89f4f568430813591f62d38d932c5 449 Gene3D G3DSA:3.40.640.10 56 317 1.2E-76 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 ALX04_RS03260 c9b89f4f568430813591f62d38d932c5 449 Gene3D G3DSA:3.90.1150.10 318 449 1.7E-34 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 ALX04_RS03260 c9b89f4f568430813591f62d38d932c5 449 Pfam PF00202 Aminotransferase class-III 31 431 4.8E-110 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 ALX04_RS03260 c9b89f4f568430813591f62d38d932c5 449 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 248 286 - T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 ALX04_RS03260 c9b89f4f568430813591f62d38d932c5 449 PIRSF PIRSF000521 128 435 6.5E-31 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 ALX04_RS03260 c9b89f4f568430813591f62d38d932c5 449 PIRSF PIRSF000521 8 147 4.1E-12 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 ALX04_RS07840 9411dc2f9efa02403a6a12f9a6c21d88 180 Pfam PF00156 Phosphoribosyl transferase domain 4 146 1.1E-22 T 28-03-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 ALX04_RS07840 9411dc2f9efa02403a6a12f9a6c21d88 180 Gene3D G3DSA:3.40.50.2020 1 180 3.3E-38 T 28-03-2018 ALX04_RS07840 9411dc2f9efa02403a6a12f9a6c21d88 180 Hamap MF_01219 Bifunctional protein PyrR [pyrR]. 2 177 38.698 T 28-03-2018 IPR023050 Bifunctional protein PyrR KEGG: 00240+2.4.2.9|MetaCyc: PWY-7183 ALX04_RS07840 9411dc2f9efa02403a6a12f9a6c21d88 180 SUPERFAMILY SSF53271 5 171 5.51E-43 T 28-03-2018 IPR029057 Phosphoribosyltransferase-like ALX04_RS00050 7131334fa4506fb2f6bd9f4e6e4f306d 431 SUPERFAMILY SSF55681 100 431 2.7E-95 T 28-03-2018 ALX04_RS00050 7131334fa4506fb2f6bd9f4e6e4f306d 431 Gene3D G3DSA:3.30.930.10 102 431 1.0E-87 T 28-03-2018 ALX04_RS00050 7131334fa4506fb2f6bd9f4e6e4f306d 431 Pfam PF01336 OB-fold nucleic acid binding domain 17 95 2.1E-10 T 28-03-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 ALX04_RS00050 7131334fa4506fb2f6bd9f4e6e4f306d 431 Pfam PF00152 tRNA synthetases class II (D, K and N) 112 425 4.3E-78 T 28-03-2018 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 ALX04_RS00050 7131334fa4506fb2f6bd9f4e6e4f306d 431 PRINTS PR01042 Aspartyl-tRNA synthetase signature 181 193 2.2E-14 T 28-03-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 ALX04_RS00050 7131334fa4506fb2f6bd9f4e6e4f306d 431 PRINTS PR01042 Aspartyl-tRNA synthetase signature 346 362 2.2E-14 T 28-03-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 ALX04_RS00050 7131334fa4506fb2f6bd9f4e6e4f306d 431 PRINTS PR01042 Aspartyl-tRNA synthetase signature 197 210 2.2E-14 T 28-03-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 ALX04_RS00050 7131334fa4506fb2f6bd9f4e6e4f306d 431 PRINTS PR01042 Aspartyl-tRNA synthetase signature 386 400 2.2E-14 T 28-03-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 ALX04_RS00050 7131334fa4506fb2f6bd9f4e6e4f306d 431 Gene3D G3DSA:2.40.50.140 1 101 9.0E-16 T 28-03-2018 ALX04_RS00050 7131334fa4506fb2f6bd9f4e6e4f306d 431 SUPERFAMILY SSF50249 10 103 3.18E-18 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold ALX04_RS00050 7131334fa4506fb2f6bd9f4e6e4f306d 431 Hamap MF_00534 Asparagine--tRNA ligase [asnS]. 2 431 40.828 T 28-03-2018 IPR004522 Asparagine-tRNA ligase GO:0000166|GO:0004816|GO:0005524|GO:0005737|GO:0006421 KEGG: 00970+6.1.1.22 ALX04_RS00050 7131334fa4506fb2f6bd9f4e6e4f306d 431 TIGRFAM TIGR00457 asnS: asparagine--tRNA ligase 8 430 1.2E-149 T 28-03-2018 IPR004522 Asparagine-tRNA ligase GO:0000166|GO:0004816|GO:0005524|GO:0005737|GO:0006421 KEGG: 00970+6.1.1.22 ALX04_RS04615 dd5e634773185a81e86f3392e761477f 569 Pfam PF04073 Aminoacyl-tRNA editing domain 257 374 1.3E-28 T 28-03-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 ALX04_RS04615 dd5e634773185a81e86f3392e761477f 569 Gene3D G3DSA:3.40.50.800 456 569 8.6E-31 T 28-03-2018 IPR004154 Anticodon-binding ALX04_RS04615 dd5e634773185a81e86f3392e761477f 569 Gene3D G3DSA:3.90.960.10 240 386 2.5E-42 T 28-03-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 ALX04_RS04615 dd5e634773185a81e86f3392e761477f 569 Gene3D G3DSA:3.30.930.10 392 455 9.3E-8 T 28-03-2018 ALX04_RS04615 dd5e634773185a81e86f3392e761477f 569 Pfam PF03129 Anticodon binding domain 472 561 1.2E-19 T 28-03-2018 IPR004154 Anticodon-binding ALX04_RS04615 dd5e634773185a81e86f3392e761477f 569 PRINTS PR01046 Prolyl-tRNA synthetase signature 104 115 6.4E-16 T 28-03-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 ALX04_RS04615 dd5e634773185a81e86f3392e761477f 569 PRINTS PR01046 Prolyl-tRNA synthetase signature 144 155 6.4E-16 T 28-03-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 ALX04_RS04615 dd5e634773185a81e86f3392e761477f 569 PRINTS PR01046 Prolyl-tRNA synthetase signature 134 142 6.4E-16 T 28-03-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 ALX04_RS04615 dd5e634773185a81e86f3392e761477f 569 PRINTS PR01046 Prolyl-tRNA synthetase signature 68 86 6.4E-16 T 28-03-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 ALX04_RS04615 dd5e634773185a81e86f3392e761477f 569 Gene3D G3DSA:3.30.930.10 1 234 4.9E-41 T 28-03-2018 ALX04_RS04615 dd5e634773185a81e86f3392e761477f 569 SUPERFAMILY SSF52954 460 567 3.62E-30 T 28-03-2018 IPR004154 Anticodon-binding ALX04_RS04615 dd5e634773185a81e86f3392e761477f 569 Hamap MF_01569 Proline--tRNA ligase [proS]. 1 566 40.587 T 28-03-2018 IPR023717 Prolyl-tRNA synthetase, class IIa, type 1 GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15 ALX04_RS04615 dd5e634773185a81e86f3392e761477f 569 TIGRFAM TIGR00409 proS_fam_II: proline--tRNA ligase 1 560 1.1E-226 T 28-03-2018 IPR004500 Prolyl-tRNA synthetase, class IIa, bacterial-type GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15 ALX04_RS04615 dd5e634773185a81e86f3392e761477f 569 SUPERFAMILY SSF55826 218 387 1.96E-37 T 28-03-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 ALX04_RS04615 dd5e634773185a81e86f3392e761477f 569 SUPERFAMILY SSF55681 9 237 2.87E-96 T 28-03-2018 ALX04_RS04615 dd5e634773185a81e86f3392e761477f 569 SUPERFAMILY SSF55681 404 475 2.87E-96 T 28-03-2018 ALX04_RS04615 dd5e634773185a81e86f3392e761477f 569 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 94 455 8.3E-59 T 28-03-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 ALX04_RS11390 9c3c2c9d1129bce348cebdd2930d4f0d 704 SMART SM01086 614 701 3.5E-30 T 28-03-2018 IPR019489 Clp ATPase, C-terminal ALX04_RS11390 9c3c2c9d1129bce348cebdd2930d4f0d 704 Gene3D G3DSA:1.10.8.60 264 398 3.3E-30 T 28-03-2018 ALX04_RS11390 9c3c2c9d1129bce348cebdd2930d4f0d 704 SUPERFAMILY SSF52540 397 682 1.11E-68 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase ALX04_RS11390 9c3c2c9d1129bce348cebdd2930d4f0d 704 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 497 515 3.1E-28 T 28-03-2018 IPR001270 ClpA/B family GO:0005524 ALX04_RS11390 9c3c2c9d1129bce348cebdd2930d4f0d 704 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 527 545 3.1E-28 T 28-03-2018 IPR001270 ClpA/B family GO:0005524 ALX04_RS11390 9c3c2c9d1129bce348cebdd2930d4f0d 704 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 560 574 3.1E-28 T 28-03-2018 IPR001270 ClpA/B family GO:0005524 ALX04_RS11390 9c3c2c9d1129bce348cebdd2930d4f0d 704 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 452 470 3.1E-28 T 28-03-2018 IPR001270 ClpA/B family GO:0005524 ALX04_RS11390 9c3c2c9d1129bce348cebdd2930d4f0d 704 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 614 684 1.1E-23 T 28-03-2018 IPR019489 Clp ATPase, C-terminal ALX04_RS11390 9c3c2c9d1129bce348cebdd2930d4f0d 704 Pfam PF02151 UvrB/uvrC motif 336 366 1.8E-4 T 28-03-2018 IPR001943 UVR domain GO:0005515 ALX04_RS11390 9c3c2c9d1129bce348cebdd2930d4f0d 704 SUPERFAMILY SSF52540 79 347 6.04E-63 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase ALX04_RS11390 9c3c2c9d1129bce348cebdd2930d4f0d 704 Gene3D G3DSA:3.40.50.300 77 263 3.0E-26 T 28-03-2018 ALX04_RS11390 9c3c2c9d1129bce348cebdd2930d4f0d 704 Gene3D G3DSA:1.10.8.60 616 700 5.1E-22 T 28-03-2018 ALX04_RS11390 9c3c2c9d1129bce348cebdd2930d4f0d 704 Pfam PF07724 AAA domain (Cdc48 subfamily) 448 606 1.1E-42 T 28-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 ALX04_RS11390 9c3c2c9d1129bce348cebdd2930d4f0d 704 SMART SM00382 117 264 5.2E-11 T 28-03-2018 IPR003593 AAA+ ATPase domain ALX04_RS11390 9c3c2c9d1129bce348cebdd2930d4f0d 704 SMART SM00382 448 615 6.2E-11 T 28-03-2018 IPR003593 AAA+ ATPase domain ALX04_RS11390 9c3c2c9d1129bce348cebdd2930d4f0d 704 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 122 254 1.6E-13 T 28-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 ALX04_RS11390 9c3c2c9d1129bce348cebdd2930d4f0d 704 Gene3D G3DSA:3.40.50.300 414 615 5.1E-34 T 28-03-2018 ALX04_RS11390 9c3c2c9d1129bce348cebdd2930d4f0d 704 ProSitePatterns PS00871 Chaperonins clpA/B signature 2. 482 500 - T 28-03-2018 IPR028299 ClpA/B, conserved site 2 ALX04_RS09020 6cbde3aa2fefb2e8f8a38d72f81b9d5d 207 SUPERFAMILY SSF46689 10 65 7.7E-8 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 ALX04_RS09020 6cbde3aa2fefb2e8f8a38d72f81b9d5d 207 Pfam PF00440 Bacterial regulatory proteins, tetR family 28 57 1.6E-4 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 ALX04_RS09020 6cbde3aa2fefb2e8f8a38d72f81b9d5d 207 Gene3D G3DSA:1.10.10.60 9 46 2.4E-6 T 28-03-2018 ALX04_RS09020 6cbde3aa2fefb2e8f8a38d72f81b9d5d 207 Pfam PF14278 Transcriptional regulator C-terminal region 95 170 2.8E-9 T 28-03-2018 ALX04_RS09020 6cbde3aa2fefb2e8f8a38d72f81b9d5d 207 Gene3D G3DSA:1.10.10.60 47 174 5.0E-5 T 28-03-2018 ALX04_RS13095 e38c031cee5ce1a67c54f821dd52c942 481 PRINTS PR01036 Tetracycline resistance protein TetB signature 168 192 4.2E-13 T 28-03-2018 ALX04_RS13095 e38c031cee5ce1a67c54f821dd52c942 481 PRINTS PR01036 Tetracycline resistance protein TetB signature 22 46 4.2E-13 T 28-03-2018 ALX04_RS13095 e38c031cee5ce1a67c54f821dd52c942 481 PRINTS PR01036 Tetracycline resistance protein TetB signature 113 133 4.2E-13 T 28-03-2018 ALX04_RS13095 e38c031cee5ce1a67c54f821dd52c942 481 PRINTS PR01036 Tetracycline resistance protein TetB signature 143 167 4.2E-13 T 28-03-2018 ALX04_RS13095 e38c031cee5ce1a67c54f821dd52c942 481 Gene3D G3DSA:1.20.1250.20 8 206 6.7E-37 T 28-03-2018 ALX04_RS13095 e38c031cee5ce1a67c54f821dd52c942 481 Gene3D G3DSA:1.20.1250.20 264 481 9.2E-29 T 28-03-2018 ALX04_RS13095 e38c031cee5ce1a67c54f821dd52c942 481 SUPERFAMILY SSF103473 253 471 3.66E-70 T 28-03-2018 IPR020846 Major facilitator superfamily domain ALX04_RS13095 e38c031cee5ce1a67c54f821dd52c942 481 SUPERFAMILY SSF103473 9 202 3.66E-70 T 28-03-2018 IPR020846 Major facilitator superfamily domain ALX04_RS13095 e38c031cee5ce1a67c54f821dd52c942 481 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 20 427 2.2E-73 T 28-03-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 ALX04_RS13095 e38c031cee5ce1a67c54f821dd52c942 481 Pfam PF07690 Major Facilitator Superfamily 24 414 2.0E-52 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 ALX04_RS05165 32a0f9ecb29d1248468629e35aeb09ee 604 Gene3D G3DSA:4.10.860.10 177 236 1.1E-14 T 28-03-2018 IPR001943 UVR domain GO:0005515 ALX04_RS05165 32a0f9ecb29d1248468629e35aeb09ee 604 Gene3D G3DSA:1.10.150.20 537 590 5.4E-12 T 28-03-2018 ALX04_RS05165 32a0f9ecb29d1248468629e35aeb09ee 604 TIGRFAM TIGR00194 uvrC: excinuclease ABC subunit C 8 571 1.6E-177 T 28-03-2018 IPR004791 UvrABC system, subunit C GO:0005737|GO:0006281|GO:0009380|GO:0009381 ALX04_RS05165 32a0f9ecb29d1248468629e35aeb09ee 604 Pfam PF01541 GIY-YIG catalytic domain 18 88 1.2E-10 T 28-03-2018 IPR000305 GIY-YIG nuclease superfamily ALX04_RS05165 32a0f9ecb29d1248468629e35aeb09ee 604 Pfam PF14520 Helix-hairpin-helix domain 539 589 7.7E-6 T 28-03-2018 ALX04_RS05165 32a0f9ecb29d1248468629e35aeb09ee 604 SUPERFAMILY SSF46600 184 236 3.92E-13 T 28-03-2018 IPR001943 UVR domain GO:0005515 ALX04_RS05165 32a0f9ecb29d1248468629e35aeb09ee 604 Hamap MF_00203 UvrABC system protein C [uvrC]. 3 588 26.328 T 28-03-2018 IPR004791 UvrABC system, subunit C GO:0005737|GO:0006281|GO:0009380|GO:0009381 ALX04_RS05165 32a0f9ecb29d1248468629e35aeb09ee 604 SUPERFAMILY SSF47781 503 586 2.26E-18 T 28-03-2018 IPR010994 RuvA domain 2-like ALX04_RS05165 32a0f9ecb29d1248468629e35aeb09ee 604 Gene3D G3DSA:3.40.1440.10 2 98 4.1E-24 T 28-03-2018 IPR000305 GIY-YIG nuclease superfamily ALX04_RS05165 32a0f9ecb29d1248468629e35aeb09ee 604 SUPERFAMILY SSF82771 16 95 3.53E-20 T 28-03-2018 IPR000305 GIY-YIG nuclease superfamily ALX04_RS05165 32a0f9ecb29d1248468629e35aeb09ee 604 SMART SM00465 16 96 5.2E-22 T 28-03-2018 IPR000305 GIY-YIG nuclease superfamily ALX04_RS05165 32a0f9ecb29d1248468629e35aeb09ee 604 Pfam PF08459 UvrC Helix-hairpin-helix N-terminal 374 524 1.2E-48 T 28-03-2018 IPR001162 UvrC family homology region ALX04_RS05165 32a0f9ecb29d1248468629e35aeb09ee 604 Pfam PF02151 UvrB/uvrC motif 198 230 1.1E-9 T 28-03-2018 IPR001943 UVR domain GO:0005515 ALX04_RS02415 e1d00edd813e33feb6e1fb0385334e52 205 TIGRFAM TIGR00277 HDIG: HDIG domain 30 105 2.0E-9 T 28-03-2018 IPR006675 HDIG domain ALX04_RS02415 e1d00edd813e33feb6e1fb0385334e52 205 Gene3D G3DSA:1.10.3210.10 13 198 1.6E-24 T 28-03-2018 ALX04_RS02415 e1d00edd813e33feb6e1fb0385334e52 205 Pfam PF01966 HD domain 31 140 4.3E-15 T 28-03-2018 IPR006674 HD domain ALX04_RS02415 e1d00edd813e33feb6e1fb0385334e52 205 SUPERFAMILY SSF109604 10 195 1.11E-35 T 28-03-2018 ALX04_RS02415 e1d00edd813e33feb6e1fb0385334e52 205 TIGRFAM TIGR00488 TIGR00488: putative HD superfamily hydrolase 24 193 1.4E-48 T 28-03-2018 IPR005249 Conserved hypothetical protein CHP00488 ALX04_RS02415 e1d00edd813e33feb6e1fb0385334e52 205 SMART SM00471 27 154 2.4E-8 T 28-03-2018 IPR003607 HD/PDEase domain ALX04_RS01385 e884331283898ae342bbe97f898f3c74 321 ProSitePatterns PS00211 ABC transporters family signature. 155 169 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 ALX04_RS01385 e884331283898ae342bbe97f898f3c74 321 SMART SM00382 38 232 2.5E-13 T 28-03-2018 IPR003593 AAA+ ATPase domain ALX04_RS01385 e884331283898ae342bbe97f898f3c74 321 SUPERFAMILY SSF52540 8 253 1.39E-74 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase ALX04_RS01385 e884331283898ae342bbe97f898f3c74 321 Pfam PF00005 ABC transporter 30 182 7.7E-35 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 ALX04_RS01385 e884331283898ae342bbe97f898f3c74 321 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 234 275 2.0E-6 T 28-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 ALX04_RS01385 e884331283898ae342bbe97f898f3c74 321 Gene3D G3DSA:3.40.50.300 5 302 4.5E-78 T 28-03-2018 ALX04_RS08070 6b127e0d83fa3bcb7c483ee13224f23e 265 Gene3D G3DSA:3.40.50.1000 1 265 3.4E-38 T 28-03-2018 IPR023214 HAD-like domain ALX04_RS08070 6b127e0d83fa3bcb7c483ee13224f23e 265 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 5 233 1.7E-25 T 28-03-2018 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 ALX04_RS08070 6b127e0d83fa3bcb7c483ee13224f23e 265 TIGRFAM TIGR00099 Cof-subfamily: Cof-like hydrolase 5 260 6.5E-52 T 28-03-2018 IPR000150 Cof family GO:0016787 ALX04_RS08070 6b127e0d83fa3bcb7c483ee13224f23e 265 SUPERFAMILY SSF56784 1 264 4.37E-62 T 28-03-2018 IPR023214 HAD-like domain ALX04_RS08070 6b127e0d83fa3bcb7c483ee13224f23e 265 Pfam PF08282 haloacid dehalogenase-like hydrolase 5 260 2.0E-56 T 28-03-2018 IPR023214 HAD-like domain ALX04_RS16045 75ba9987bbdf4b64f2c4665797a66078 150 Gene3D G3DSA:3.40.50.360 1 142 2.8E-12 T 28-03-2018 IPR029039 Flavoprotein-like domain ALX04_RS16045 75ba9987bbdf4b64f2c4665797a66078 150 Pfam PF07972 NrdI Flavodoxin like 1 133 1.1E-35 T 28-03-2018 IPR004465 Ribonucleotide reductase Class Ib, NrdI ALX04_RS16045 75ba9987bbdf4b64f2c4665797a66078 150 PIRSF PIRSF005087 1 144 2.7E-34 T 28-03-2018 IPR004465 Ribonucleotide reductase Class Ib, NrdI ALX04_RS16045 75ba9987bbdf4b64f2c4665797a66078 150 SUPERFAMILY SSF52218 1 136 1.75E-14 T 28-03-2018 IPR029039 Flavoprotein-like domain ALX04_RS05100 19562b5be0f77a7304d42c86127bb8e0 305 Pfam PF00294 pfkB family carbohydrate kinase 10 281 3.0E-47 T 28-03-2018 IPR011611 Carbohydrate kinase PfkB ALX04_RS05100 19562b5be0f77a7304d42c86127bb8e0 305 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 243 256 - T 28-03-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 ALX04_RS05100 19562b5be0f77a7304d42c86127bb8e0 305 Gene3D G3DSA:2.20.150.10 9 42 7.6E-13 T 28-03-2018 IPR023314 Tagatose-6-phosphate kinase/1-phosphofructokinase N-terminal domain ALX04_RS05100 19562b5be0f77a7304d42c86127bb8e0 305 TIGRFAM TIGR03828 pfkB: 1-phosphofructokinase 2 301 2.1E-104 T 28-03-2018 IPR022463 Fructose 1-phosphate kinase GO:0008662 KEGG: 00051+2.7.1.56 ALX04_RS05100 19562b5be0f77a7304d42c86127bb8e0 305 PIRSF PIRSF000535 1 303 8.1E-85 T 28-03-2018 IPR017583 Tagatose/fructose phosphokinase GO:0005975|GO:0016773 ALX04_RS05100 19562b5be0f77a7304d42c86127bb8e0 305 TIGRFAM TIGR03168 1-PFK: hexose kinase, 1-phosphofructokinase family 2 301 2.9E-104 T 28-03-2018 IPR017583 Tagatose/fructose phosphokinase GO:0005975|GO:0016773 ALX04_RS05100 19562b5be0f77a7304d42c86127bb8e0 305 SUPERFAMILY SSF53613 1 284 3.9E-63 T 28-03-2018 IPR029056 Ribokinase-like ALX04_RS05100 19562b5be0f77a7304d42c86127bb8e0 305 Gene3D G3DSA:3.40.1190.20 43 304 5.6E-39 T 28-03-2018 IPR029056 Ribokinase-like ALX04_RS05910 a88a394aa4a67387bd5eb06562f5a5b3 106 Pfam PF02635 DsrE/DsrF-like family 45 106 6.5E-6 T 28-03-2018 IPR003787 Sulphur relay, DsrE/F-like protein ALX04_RS05910 a88a394aa4a67387bd5eb06562f5a5b3 106 Gene3D G3DSA:3.40.1260.10 1 106 3.0E-22 T 28-03-2018 ALX04_RS05910 a88a394aa4a67387bd5eb06562f5a5b3 106 SUPERFAMILY SSF75169 4 106 1.24E-19 T 28-03-2018 IPR027396 DsrEFH-like ALX04_RS05370 833917e38fea709d05ac96d6adb04588 319 SUPERFAMILY SSF111331 5 308 4.09E-66 T 28-03-2018 IPR016064 NAD kinase/diacylglycerol kinase-like domain ALX04_RS05370 833917e38fea709d05ac96d6adb04588 319 SMART SM00046 4 137 8.7E-5 T 28-03-2018 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 ALX04_RS05370 833917e38fea709d05ac96d6adb04588 319 Pfam PF00781 Diacylglycerol kinase catalytic domain 5 126 3.4E-29 T 28-03-2018 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 ALX04_RS05370 833917e38fea709d05ac96d6adb04588 319 TIGRFAM TIGR00147 TIGR00147: lipid kinase, YegS/Rv2252/BmrU family 3 302 2.8E-37 T 28-03-2018 IPR005218 Diacylglycerol/lipid kinase ALX04_RS05370 833917e38fea709d05ac96d6adb04588 319 Gene3D G3DSA:3.40.50.10330 3 137 1.8E-31 T 28-03-2018 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, domain 1 GO:0003951|GO:0008152 ALX04_RS00500 69880af5563175a09ccb6311c56fa0d3 121 Gene3D G3DSA:4.10.910.10 67 85 3.3E-16 T 28-03-2018 IPR027437 30s ribosomal protein S13, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 ALX04_RS00500 69880af5563175a09ccb6311c56fa0d3 121 SUPERFAMILY SSF46946 2 114 2.62E-43 T 28-03-2018 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 ALX04_RS00500 69880af5563175a09ccb6311c56fa0d3 121 Gene3D G3DSA:4.10.910.10 86 121 1.0E-24 T 28-03-2018 IPR027437 30s ribosomal protein S13, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 ALX04_RS00500 69880af5563175a09ccb6311c56fa0d3 121 Gene3D G3DSA:1.10.8.50 1 66 7.2E-23 T 28-03-2018 ALX04_RS00500 69880af5563175a09ccb6311c56fa0d3 121 PIRSF PIRSF002134 1 121 1.9E-41 T 28-03-2018 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 ALX04_RS00500 69880af5563175a09ccb6311c56fa0d3 121 Pfam PF00416 Ribosomal protein S13/S18 3 108 6.4E-29 T 28-03-2018 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 ALX04_RS00500 69880af5563175a09ccb6311c56fa0d3 121 Hamap MF_01315 30S ribosomal protein S13 [rpsM]. 1 119 27.044 T 28-03-2018 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 ALX04_RS00500 69880af5563175a09ccb6311c56fa0d3 121 ProSitePatterns PS00646 Ribosomal protein S13 signature. 87 100 - T 28-03-2018 IPR018269 Ribosomal protein S13, conserved site GO:0003723|GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 ALX04_RS00500 69880af5563175a09ccb6311c56fa0d3 121 TIGRFAM TIGR03631 uS13_bact: ribosomal protein uS13 3 113 8.0E-50 T 28-03-2018 IPR019980 Ribosomal protein S13, bacterial-type GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 ALX04_RS00905 2c5c85ee67894bb943feff0e71c00043 779 Pfam PF00122 E1-E2 ATPase 100 279 4.4E-42 T 28-03-2018 ALX04_RS00905 2c5c85ee67894bb943feff0e71c00043 779 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 302 308 - T 28-03-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 ALX04_RS00905 2c5c85ee67894bb943feff0e71c00043 779 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 532 548 3.1E-11 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 ALX04_RS00905 2c5c85ee67894bb943feff0e71c00043 779 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 398 416 3.1E-11 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 ALX04_RS00905 2c5c85ee67894bb943feff0e71c00043 779 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 563 588 3.1E-11 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 ALX04_RS00905 2c5c85ee67894bb943feff0e71c00043 779 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 504 520 3.1E-11 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 ALX04_RS00905 2c5c85ee67894bb943feff0e71c00043 779 Gene3D G3DSA:1.20.1110.10 453 766 2.3E-39 T 28-03-2018 ALX04_RS00905 2c5c85ee67894bb943feff0e71c00043 779 Pfam PF00702 haloacid dehalogenase-like hydrolase 296 546 1.2E-24 T 28-03-2018 ALX04_RS00905 2c5c85ee67894bb943feff0e71c00043 779 SUPERFAMILY SSF81665 581 763 7.59E-59 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 ALX04_RS00905 2c5c85ee67894bb943feff0e71c00043 779 SUPERFAMILY SSF81665 8 103 7.59E-59 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 ALX04_RS00905 2c5c85ee67894bb943feff0e71c00043 779 SUPERFAMILY SSF81665 201 294 7.59E-59 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 ALX04_RS00905 2c5c85ee67894bb943feff0e71c00043 779 SUPERFAMILY SSF56784 395 611 1.17E-37 T 28-03-2018 IPR023214 HAD-like domain ALX04_RS00905 2c5c85ee67894bb943feff0e71c00043 779 SUPERFAMILY SSF56784 298 318 1.17E-37 T 28-03-2018 IPR023214 HAD-like domain ALX04_RS00905 2c5c85ee67894bb943feff0e71c00043 779 SUPERFAMILY SSF81660 325 443 5.63E-10 T 28-03-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 ALX04_RS00905 2c5c85ee67894bb943feff0e71c00043 779 SUPERFAMILY SSF81653 104 198 6.15E-22 T 28-03-2018 IPR008250 P-type ATPase, A domain Reactome: R-HSA-936837 ALX04_RS00905 2c5c85ee67894bb943feff0e71c00043 779 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 300 314 2.6E-22 T 28-03-2018 ALX04_RS00905 2c5c85ee67894bb943feff0e71c00043 779 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 150 164 2.6E-22 T 28-03-2018 ALX04_RS00905 2c5c85ee67894bb943feff0e71c00043 779 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 433 444 2.6E-22 T 28-03-2018 ALX04_RS00905 2c5c85ee67894bb943feff0e71c00043 779 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 532 551 2.6E-22 T 28-03-2018 ALX04_RS00905 2c5c85ee67894bb943feff0e71c00043 779 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 455 465 2.6E-22 T 28-03-2018 ALX04_RS00905 2c5c85ee67894bb943feff0e71c00043 779 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 555 567 2.6E-22 T 28-03-2018 ALX04_RS00905 2c5c85ee67894bb943feff0e71c00043 779 Gene3D G3DSA:3.40.1110.10 246 428 5.1E-22 T 28-03-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 ALX04_RS00905 2c5c85ee67894bb943feff0e71c00043 779 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 73 478 2.1E-49 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 ALX04_RS00905 2c5c85ee67894bb943feff0e71c00043 779 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 505 617 5.8E-28 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 ALX04_RS00905 2c5c85ee67894bb943feff0e71c00043 779 Gene3D G3DSA:2.70.150.10 2 200 5.8E-31 T 28-03-2018 ALX04_RS01020 d3dca11caca4358a957322506dda85fd 527 Pfam PF12708 Pectate lyase superfamily protein 8 109 3.4E-9 T 28-03-2018 IPR024535 Pectate lyase superfamily protein ALX04_RS01020 d3dca11caca4358a957322506dda85fd 527 SUPERFAMILY SSF51126 7 303 8.44E-15 T 28-03-2018 IPR011050 Pectin lyase fold/virulence factor ALX04_RS01020 d3dca11caca4358a957322506dda85fd 527 Gene3D G3DSA:2.160.20.10 79 408 0.061 T 28-03-2018 IPR012334 Pectin lyase fold ALX04_RS01020 d3dca11caca4358a957322506dda85fd 527 Gene3D G3DSA:2.160.20.10 2 78 9.0E-13 T 28-03-2018 IPR012334 Pectin lyase fold ALX04_RS02745 cd8577b838a00ebb06d1f2cd9307af89 152 Gene3D G3DSA:1.10.10.10 3 66 4.0E-24 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS02745 cd8577b838a00ebb06d1f2cd9307af89 152 PRINTS PR01467 Bacterial arginine repressor signature 21 34 8.4E-12 T 28-03-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 ALX04_RS02745 cd8577b838a00ebb06d1f2cd9307af89 152 PRINTS PR01467 Bacterial arginine repressor signature 88 101 8.4E-12 T 28-03-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 ALX04_RS02745 cd8577b838a00ebb06d1f2cd9307af89 152 PRINTS PR01467 Bacterial arginine repressor signature 118 133 8.4E-12 T 28-03-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 ALX04_RS02745 cd8577b838a00ebb06d1f2cd9307af89 152 PRINTS PR01467 Bacterial arginine repressor signature 37 52 8.4E-12 T 28-03-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 ALX04_RS02745 cd8577b838a00ebb06d1f2cd9307af89 152 Gene3D G3DSA:3.30.1360.40 74 146 1.4E-18 T 28-03-2018 IPR024946 Arginine repressor C-terminal-like domain Reactome: R-HSA-4615885 ALX04_RS02745 cd8577b838a00ebb06d1f2cd9307af89 152 ProDom PD007402 ARGININE REPRESSOR TRANSCRIPTION BIOSYNTHESIS DNA-BINDING REGULATION AMINO-ACID ARGR TRANSCRIPTIONAL FAMILY 90 134 3.0E-6 T 28-03-2018 IPR020899 Arginine repressor, C-terminal GO:0034618|GO:0051259 ALX04_RS02745 cd8577b838a00ebb06d1f2cd9307af89 152 Hamap MF_00173 Arginine repressor [argR]. 1 152 53.732 T 28-03-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 ALX04_RS02745 cd8577b838a00ebb06d1f2cd9307af89 152 SUPERFAMILY SSF46785 3 78 3.13E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS02745 cd8577b838a00ebb06d1f2cd9307af89 152 SUPERFAMILY SSF55252 80 148 1.27E-15 T 28-03-2018 IPR020899 Arginine repressor, C-terminal GO:0034618|GO:0051259 ALX04_RS02745 cd8577b838a00ebb06d1f2cd9307af89 152 Pfam PF01316 Arginine repressor, DNA binding domain 1 68 1.5E-21 T 28-03-2018 IPR020900 Arginine repressor, DNA-binding domain GO:0003700|GO:0006355|GO:0006525 ALX04_RS02745 cd8577b838a00ebb06d1f2cd9307af89 152 Pfam PF02863 Arginine repressor, C-terminal domain 80 146 4.0E-16 T 28-03-2018 IPR020899 Arginine repressor, C-terminal GO:0034618|GO:0051259 ALX04_RS09985 0c3c707a2167d555272206587e24305c 555 Gene3D G3DSA:3.20.20.470 1 104 3.7E-34 T 28-03-2018 ALX04_RS09985 0c3c707a2167d555272206587e24305c 555 Gene3D G3DSA:3.20.20.470 172 347 2.7E-29 T 28-03-2018 ALX04_RS09985 0c3c707a2167d555272206587e24305c 555 SUPERFAMILY SSF51011 487 550 7.44E-6 T 28-03-2018 ALX04_RS09985 0c3c707a2167d555272206587e24305c 555 SMART SM00642 13 422 3.0E-114 T 28-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 ALX04_RS09985 0c3c707a2167d555272206587e24305c 555 Gene3D G3DSA:3.90.400.10 105 171 4.3E-24 T 28-03-2018 ALX04_RS09985 0c3c707a2167d555272206587e24305c 555 Pfam PF00128 Alpha amylase, catalytic domain 28 380 1.8E-93 T 28-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 ALX04_RS09985 0c3c707a2167d555272206587e24305c 555 Gene3D G3DSA:3.20.20.80 348 477 3.0E-16 T 28-03-2018 ALX04_RS09985 0c3c707a2167d555272206587e24305c 555 SUPERFAMILY SSF51445 4 476 7.53E-128 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily ALX04_RS09325 2482b3d9118d2443a03e829059056881 136 Pfam PF07883 Cupin domain 48 108 5.7E-9 T 28-03-2018 IPR013096 Cupin 2, conserved barrel ALX04_RS09325 2482b3d9118d2443a03e829059056881 136 SUPERFAMILY SSF51182 5 135 4.89E-25 T 28-03-2018 IPR011051 RmlC-like cupin domain ALX04_RS09325 2482b3d9118d2443a03e829059056881 136 Gene3D G3DSA:2.60.120.10 9 136 1.3E-26 T 28-03-2018 IPR014710 RmlC-like jelly roll fold ALX04_RS15075 d1f39a67491f348ea7a6ca0e6c126782 157 Pfam PF00847 AP2 domain 104 134 1.7E-4 T 28-03-2018 IPR001471 AP2/ERF domain GO:0003700|GO:0006355 ALX04_RS12640 23935aaa9eae0b13bdb794bf093443da 372 TIGRFAM TIGR03583 EF_0837: putative amidohydrolase, EF_0837/AHA_3915 family 3 366 1.2E-174 T 28-03-2018 IPR020043 Amidohydrolase EF0837/AHA3915, putative ALX04_RS12640 23935aaa9eae0b13bdb794bf093443da 372 PIRSF PIRSF039004 1 372 1.5E-120 T 28-03-2018 IPR020043 Amidohydrolase EF0837/AHA3915, putative ALX04_RS12640 23935aaa9eae0b13bdb794bf093443da 372 SUPERFAMILY SSF51338 318 333 2.73E-11 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 ALX04_RS12640 23935aaa9eae0b13bdb794bf093443da 372 SUPERFAMILY SSF51338 2 52 2.73E-11 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 ALX04_RS12640 23935aaa9eae0b13bdb794bf093443da 372 SUPERFAMILY SSF51556 52 318 1.47E-67 T 28-03-2018 IPR032466 Metal-dependent hydrolase ALX04_RS12640 23935aaa9eae0b13bdb794bf093443da 372 Pfam PF07969 Amidohydrolase family 295 365 7.0E-8 T 28-03-2018 IPR013108 Amidohydrolase 3 ALX04_RS12640 23935aaa9eae0b13bdb794bf093443da 372 Gene3D G3DSA:2.30.40.10 1 66 6.4E-12 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 ALX04_RS12640 23935aaa9eae0b13bdb794bf093443da 372 Gene3D G3DSA:3.20.20.140 67 317 4.2E-39 T 28-03-2018 ALX04_RS05860 5cdca3f3be90323b8c2c262a34f6862e 397 TIGRFAM TIGR00016 ackA: acetate kinase 3 394 1.7E-137 T 28-03-2018 IPR004372 Acetate/propionate kinase GO:0006082|GO:0016301|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 ALX04_RS05860 5cdca3f3be90323b8c2c262a34f6862e 397 Hamap MF_00020 Acetate kinase [ackA]. 1 397 170.629 T 28-03-2018 IPR004372 Acetate/propionate kinase GO:0006082|GO:0016301|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 ALX04_RS05860 5cdca3f3be90323b8c2c262a34f6862e 397 ProSitePatterns PS01076 Acetate and butyrate kinases family signature 2. 203 220 - T 28-03-2018 IPR023865 Aliphatic acid kinase, short-chain, conserved site GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 ALX04_RS05860 5cdca3f3be90323b8c2c262a34f6862e 397 Gene3D G3DSA:3.30.420.40 196 397 9.4E-74 T 28-03-2018 ALX04_RS05860 5cdca3f3be90323b8c2c262a34f6862e 397 ProSitePatterns PS01075 Acetate and butyrate kinases family signature 1. 4 15 - T 28-03-2018 IPR023865 Aliphatic acid kinase, short-chain, conserved site GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 ALX04_RS05860 5cdca3f3be90323b8c2c262a34f6862e 397 Gene3D G3DSA:3.30.420.40 3 195 1.4E-68 T 28-03-2018 ALX04_RS05860 5cdca3f3be90323b8c2c262a34f6862e 397 PRINTS PR00471 Acetate kinase family signature 321 337 8.9E-36 T 28-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 ALX04_RS05860 5cdca3f3be90323b8c2c262a34f6862e 397 PRINTS PR00471 Acetate kinase family signature 4 15 8.9E-36 T 28-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 ALX04_RS05860 5cdca3f3be90323b8c2c262a34f6862e 397 PRINTS PR00471 Acetate kinase family signature 173 186 8.9E-36 T 28-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 ALX04_RS05860 5cdca3f3be90323b8c2c262a34f6862e 397 PRINTS PR00471 Acetate kinase family signature 203 224 8.9E-36 T 28-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 ALX04_RS05860 5cdca3f3be90323b8c2c262a34f6862e 397 PRINTS PR00471 Acetate kinase family signature 299 312 8.9E-36 T 28-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 ALX04_RS05860 5cdca3f3be90323b8c2c262a34f6862e 397 PRINTS PR00471 Acetate kinase family signature 375 387 8.9E-36 T 28-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 ALX04_RS05860 5cdca3f3be90323b8c2c262a34f6862e 397 SUPERFAMILY SSF53067 157 394 2.37E-80 T 28-03-2018 ALX04_RS05860 5cdca3f3be90323b8c2c262a34f6862e 397 Pfam PF00871 Acetokinase family 4 388 3.0E-133 T 28-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 ALX04_RS05860 5cdca3f3be90323b8c2c262a34f6862e 397 PIRSF PIRSF000722 2 397 2.1E-135 T 28-03-2018 IPR004372 Acetate/propionate kinase GO:0006082|GO:0016301|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 ALX04_RS05860 5cdca3f3be90323b8c2c262a34f6862e 397 SUPERFAMILY SSF53067 3 195 7.12E-63 T 28-03-2018 ALX04_RS08660 fc5e692e137aa4f868eb5662e7ecf0ea 283 ProSitePatterns PS00062 Aldo/keto reductase family signature 2. 118 135 - T 28-03-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 ALX04_RS08660 fc5e692e137aa4f868eb5662e7ecf0ea 283 Pfam PF00248 Aldo/keto reductase family 17 255 6.5E-45 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain ALX04_RS08660 fc5e692e137aa4f868eb5662e7ecf0ea 283 PIRSF PIRSF000097 108 277 4.8E-43 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 ALX04_RS08660 fc5e692e137aa4f868eb5662e7ecf0ea 283 PIRSF PIRSF000097 1 110 4.1E-33 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 ALX04_RS08660 fc5e692e137aa4f868eb5662e7ecf0ea 283 SUPERFAMILY SSF51430 5 265 2.75E-80 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain ALX04_RS08660 fc5e692e137aa4f868eb5662e7ecf0ea 283 PRINTS PR00069 Aldo-keto reductase signature 191 215 5.4E-37 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 ALX04_RS08660 fc5e692e137aa4f868eb5662e7ecf0ea 283 PRINTS PR00069 Aldo-keto reductase signature 89 107 5.4E-37 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 ALX04_RS08660 fc5e692e137aa4f868eb5662e7ecf0ea 283 PRINTS PR00069 Aldo-keto reductase signature 118 135 5.4E-37 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 ALX04_RS08660 fc5e692e137aa4f868eb5662e7ecf0ea 283 PRINTS PR00069 Aldo-keto reductase signature 152 181 5.4E-37 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 ALX04_RS08660 fc5e692e137aa4f868eb5662e7ecf0ea 283 PRINTS PR00069 Aldo-keto reductase signature 36 60 5.4E-37 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 ALX04_RS08660 fc5e692e137aa4f868eb5662e7ecf0ea 283 Gene3D G3DSA:3.20.20.100 3 282 3.0E-85 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain ALX04_RS08660 fc5e692e137aa4f868eb5662e7ecf0ea 283 ProSitePatterns PS00798 Aldo/keto reductase family signature 1. 40 57 - T 28-03-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 ALX04_RS05205 180d16847813bc5c1049d6d78b5d521c 440 SUPERFAMILY SSF102735 1 128 3.01E-39 T 28-03-2018 IPR008881 Trigger factor, ribosome-binding, bacterial GO:0006457|GO:0015031 ALX04_RS05205 180d16847813bc5c1049d6d78b5d521c 440 Pfam PF05698 Bacterial trigger factor protein (TF) C-terminus 264 421 5.8E-40 T 28-03-2018 IPR008880 Trigger factor, C-terminal GO:0006457|GO:0015031 ALX04_RS05205 180d16847813bc5c1049d6d78b5d521c 440 SUPERFAMILY SSF109998 250 434 7.19E-39 T 28-03-2018 IPR027304 Trigger factor/SurA domain ALX04_RS05205 180d16847813bc5c1049d6d78b5d521c 440 SUPERFAMILY SSF54534 88 243 8.25E-38 T 28-03-2018 ALX04_RS05205 180d16847813bc5c1049d6d78b5d521c 440 Pfam PF00254 FKBP-type peptidyl-prolyl cis-trans isomerase 159 238 2.2E-14 T 28-03-2018 IPR001179 FKBP-type peptidyl-prolyl cis-trans isomerase domain ALX04_RS05205 180d16847813bc5c1049d6d78b5d521c 440 Gene3D G3DSA:3.30.70.1050 1 119 1.2E-37 T 28-03-2018 IPR008881 Trigger factor, ribosome-binding, bacterial GO:0006457|GO:0015031 ALX04_RS05205 180d16847813bc5c1049d6d78b5d521c 440 PIRSF PIRSF003095 1 440 2.9E-132 T 28-03-2018 IPR005215 Trigger factor GO:0015031 ALX04_RS05205 180d16847813bc5c1049d6d78b5d521c 440 Pfam PF05697 Bacterial trigger factor protein (TF) 1 143 1.3E-42 T 28-03-2018 IPR008881 Trigger factor, ribosome-binding, bacterial GO:0006457|GO:0015031 ALX04_RS05205 180d16847813bc5c1049d6d78b5d521c 440 Hamap MF_00303 Trigger factor [tig]. 1 427 22.827 T 28-03-2018 IPR005215 Trigger factor GO:0015031 ALX04_RS05205 180d16847813bc5c1049d6d78b5d521c 440 Gene3D G3DSA:1.10.3120.10 213 400 1.5E-53 T 28-03-2018 IPR008880 Trigger factor, C-terminal GO:0006457|GO:0015031 ALX04_RS05205 180d16847813bc5c1049d6d78b5d521c 440 TIGRFAM TIGR00115 tig: trigger factor 12 420 1.6E-137 T 28-03-2018 IPR005215 Trigger factor GO:0015031 ALX04_RS01710 effe99e40c2a9711baee4cbab0b1aa7e 126 Hamap MF_00115 Large-conductance mechanosensitive channel [mscL]. 1 124 25.845 T 28-03-2018 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 ALX04_RS01710 effe99e40c2a9711baee4cbab0b1aa7e 126 TIGRFAM TIGR00220 mscL: large conductance mechanosensitive channel protein 1 123 5.7E-41 T 28-03-2018 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 ALX04_RS01710 effe99e40c2a9711baee4cbab0b1aa7e 126 SUPERFAMILY SSF81330 11 117 1.31E-33 T 28-03-2018 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 ALX04_RS01710 effe99e40c2a9711baee4cbab0b1aa7e 126 PRINTS PR01264 Bacterial mechano-sensitive ion channel signature 4 18 4.8E-11 T 28-03-2018 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 ALX04_RS01710 effe99e40c2a9711baee4cbab0b1aa7e 126 PRINTS PR01264 Bacterial mechano-sensitive ion channel signature 84 93 4.8E-11 T 28-03-2018 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 ALX04_RS01710 effe99e40c2a9711baee4cbab0b1aa7e 126 PRINTS PR01264 Bacterial mechano-sensitive ion channel signature 75 83 4.8E-11 T 28-03-2018 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 ALX04_RS01710 effe99e40c2a9711baee4cbab0b1aa7e 126 Pfam PF01741 Large-conductance mechanosensitive channel, MscL 1 121 7.3E-44 T 28-03-2018 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 ALX04_RS01710 effe99e40c2a9711baee4cbab0b1aa7e 126 ProSitePatterns PS01327 Large-conductance mechanosensitive channels mscL family signature. 11 24 - T 28-03-2018 IPR019823 Large-conductance mechanosensitive channel, conserved site ALX04_RS01415 bf231182968fdf10c91480562c52f821 576 ProSitePatterns PS00742 PEP-utilizing enzymes signature 2. 450 468 - T 28-03-2018 IPR023151 PEP-utilising enzyme, conserved site GO:0016772 ALX04_RS01415 bf231182968fdf10c91480562c52f821 576 Pfam PF05524 PEP-utilising enzyme, N-terminal 7 129 1.7E-34 T 28-03-2018 IPR008731 Phosphotransferase system, enzyme I N-terminal GO:0009401 ALX04_RS01415 bf231182968fdf10c91480562c52f821 576 TIGRFAM TIGR01417 PTS_I_fam: phosphoenolpyruvate-protein phosphotransferase 6 570 1.4E-238 T 28-03-2018 IPR006318 Phosphotransferase system, enzyme I-like GO:0016772 ALX04_RS01415 bf231182968fdf10c91480562c52f821 576 Gene3D G3DSA:3.50.30.10 138 257 2.3E-29 T 28-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 ALX04_RS01415 bf231182968fdf10c91480562c52f821 576 Gene3D G3DSA:3.20.20.60 258 575 5.8E-98 T 28-03-2018 ALX04_RS01415 bf231182968fdf10c91480562c52f821 576 SUPERFAMILY SSF47831 25 146 3.01E-36 T 28-03-2018 IPR008731 Phosphotransferase system, enzyme I N-terminal GO:0009401 ALX04_RS01415 bf231182968fdf10c91480562c52f821 576 Pfam PF02896 PEP-utilising enzyme, TIM barrel domain 253 544 2.0E-122 T 28-03-2018 IPR000121 PEP-utilising enzyme, C-terminal GO:0016310|GO:0016772 ALX04_RS01415 bf231182968fdf10c91480562c52f821 576 SUPERFAMILY SSF52009 128 249 2.88E-36 T 28-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 ALX04_RS01415 bf231182968fdf10c91480562c52f821 576 Pfam PF00391 PEP-utilising enzyme, mobile domain 156 228 1.4E-24 T 28-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 ALX04_RS01415 bf231182968fdf10c91480562c52f821 576 SUPERFAMILY SSF51621 252 552 1.23E-109 T 28-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 ALX04_RS01415 bf231182968fdf10c91480562c52f821 576 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 296 315 6.3E-29 T 28-03-2018 ALX04_RS01415 bf231182968fdf10c91480562c52f821 576 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 450 465 6.3E-29 T 28-03-2018 ALX04_RS01415 bf231182968fdf10c91480562c52f821 576 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 503 515 6.3E-29 T 28-03-2018 ALX04_RS01415 bf231182968fdf10c91480562c52f821 576 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 467 482 6.3E-29 T 28-03-2018 ALX04_RS01415 bf231182968fdf10c91480562c52f821 576 PIRSF PIRSF000732 1 576 3.9E-217 T 28-03-2018 IPR024692 Phosphotransferase system, enzyme I GO:0008965|GO:0009401 ALX04_RS01415 bf231182968fdf10c91480562c52f821 576 Gene3D G3DSA:1.10.274.10 27 137 5.8E-39 T 28-03-2018 IPR008731 Phosphotransferase system, enzyme I N-terminal GO:0009401 ALX04_RS01415 bf231182968fdf10c91480562c52f821 576 ProSitePatterns PS00370 PEP-utilizing enzymes phosphorylation site signature. 187 198 - T 28-03-2018 IPR018274 PEP-utilising enzyme, active site GO:0016310|GO:0016772 ALX04_RS00145 436e081381a343f10364ff5d344b73b0 400 SUPERFAMILY SSF55021 332 397 5.8E-15 T 28-03-2018 ALX04_RS00145 436e081381a343f10364ff5d344b73b0 400 Pfam PF13840 ACT domain 332 394 3.3E-21 T 28-03-2018 IPR027795 GATS-like ACT domain ALX04_RS00145 436e081381a343f10364ff5d344b73b0 400 Gene3D G3DSA:3.30.70.260 242 328 4.9E-11 T 28-03-2018 ALX04_RS00145 436e081381a343f10364ff5d344b73b0 400 Gene3D G3DSA:3.30.2130.10 329 400 9.1E-15 T 28-03-2018 ALX04_RS00145 436e081381a343f10364ff5d344b73b0 400 SUPERFAMILY SSF55021 259 342 1.53E-7 T 28-03-2018 ALX04_RS00145 436e081381a343f10364ff5d344b73b0 400 TIGRFAM TIGR00657 asp_kinases: aspartate kinase 67 397 3.7E-85 T 28-03-2018 IPR001341 Aspartate kinase domain GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 ALX04_RS00145 436e081381a343f10364ff5d344b73b0 400 Gene3D G3DSA:3.40.1160.10 1 241 4.3E-62 T 28-03-2018 ALX04_RS00145 436e081381a343f10364ff5d344b73b0 400 Pfam PF00696 Amino acid kinase family 3 235 9.0E-46 T 28-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase ALX04_RS00145 436e081381a343f10364ff5d344b73b0 400 ProSitePatterns PS00324 Aspartokinase signature. 5 13 - T 28-03-2018 IPR018042 Aspartate kinase, conserved site GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 ALX04_RS00145 436e081381a343f10364ff5d344b73b0 400 PIRSF PIRSF000726 1 65 3.7E-9 T 28-03-2018 IPR005260 Aspartate kinase, monofunctional class GO:0004072|GO:0009089 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 ALX04_RS00145 436e081381a343f10364ff5d344b73b0 400 PIRSF PIRSF000726 58 399 3.9E-81 T 28-03-2018 IPR005260 Aspartate kinase, monofunctional class GO:0004072|GO:0009089 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 ALX04_RS00145 436e081381a343f10364ff5d344b73b0 400 SUPERFAMILY SSF53633 3 249 7.33E-65 T 28-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase ALX04_RS01210 8bb40a0a8f9ec1e0b208c337c52f60e4 258 Pfam PF14393 Domain of unknown function (DUF4422) 4 219 7.7E-85 T 28-03-2018 IPR025536 Domain of unknown function DUF4422 ALX04_RS10140 808328ce7e111a8dd494066bdadebef3 279 SUPERFAMILY SSF82549 1 276 4.45E-78 T 28-03-2018 ALX04_RS10140 808328ce7e111a8dd494066bdadebef3 279 Pfam PF02645 Uncharacterised protein, DegV family COG1307 2 276 6.6E-73 T 28-03-2018 IPR003797 DegV ALX04_RS10140 808328ce7e111a8dd494066bdadebef3 279 TIGRFAM TIGR00762 DegV: EDD domain protein, DegV family 3 276 5.5E-84 T 28-03-2018 IPR003797 DegV ALX04_RS10140 808328ce7e111a8dd494066bdadebef3 279 Gene3D G3DSA:3.40.50.10170 1 149 5.7E-42 T 28-03-2018 ALX04_RS10140 808328ce7e111a8dd494066bdadebef3 279 Gene3D G3DSA:3.30.1180.10 151 277 1.3E-28 T 28-03-2018 ALX04_RS14765 400fd71f82d9fcd601c4df8a2c242ea6 442 Hamap MF_00318 Enolase [eno]. 2 416 46.045 T 28-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 ALX04_RS14765 400fd71f82d9fcd601c4df8a2c242ea6 442 PRINTS PR00148 Enolase signature 161 174 2.6E-47 T 28-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 ALX04_RS14765 400fd71f82d9fcd601c4df8a2c242ea6 442 PRINTS PR00148 Enolase signature 316 327 2.6E-47 T 28-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 ALX04_RS14765 400fd71f82d9fcd601c4df8a2c242ea6 442 PRINTS PR00148 Enolase signature 368 385 2.6E-47 T 28-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 ALX04_RS14765 400fd71f82d9fcd601c4df8a2c242ea6 442 PRINTS PR00148 Enolase signature 37 51 2.6E-47 T 28-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 ALX04_RS14765 400fd71f82d9fcd601c4df8a2c242ea6 442 PRINTS PR00148 Enolase signature 339 353 2.6E-47 T 28-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 ALX04_RS14765 400fd71f82d9fcd601c4df8a2c242ea6 442 PRINTS PR00148 Enolase signature 107 123 2.6E-47 T 28-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 ALX04_RS14765 400fd71f82d9fcd601c4df8a2c242ea6 442 Gene3D G3DSA:3.30.390.10 3 127 2.4E-55 T 28-03-2018 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 ALX04_RS14765 400fd71f82d9fcd601c4df8a2c242ea6 442 PIRSF PIRSF001400 1 430 6.7E-199 T 28-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 ALX04_RS14765 400fd71f82d9fcd601c4df8a2c242ea6 442 SMART SM01193 4 134 6.5E-98 T 28-03-2018 IPR020811 Enolase, N-terminal KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 ALX04_RS14765 400fd71f82d9fcd601c4df8a2c242ea6 442 Pfam PF03952 Enolase, N-terminal domain 4 134 2.1E-62 T 28-03-2018 IPR020811 Enolase, N-terminal KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 ALX04_RS14765 400fd71f82d9fcd601c4df8a2c242ea6 442 Pfam PF00113 Enolase, C-terminal TIM barrel domain 140 427 2.4E-135 T 28-03-2018 IPR020810 Enolase, C-terminal TIM barrel domain KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 ALX04_RS14765 400fd71f82d9fcd601c4df8a2c242ea6 442 ProSitePatterns PS00164 Enolase signature. 339 352 - T 28-03-2018 IPR020809 Enolase, conserved site KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|Reactome: R-HSA-70171|Reactome: R-HSA-70263 ALX04_RS14765 400fd71f82d9fcd601c4df8a2c242ea6 442 TIGRFAM TIGR01060 eno: phosphopyruvate hydratase 4 430 4.6E-215 T 28-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 ALX04_RS14765 400fd71f82d9fcd601c4df8a2c242ea6 442 Gene3D G3DSA:3.20.20.120 128 438 2.8E-107 T 28-03-2018 IPR029065 Enolase C-terminal domain-like ALX04_RS14765 400fd71f82d9fcd601c4df8a2c242ea6 442 SUPERFAMILY SSF51604 138 430 1.36E-130 T 28-03-2018 IPR029065 Enolase C-terminal domain-like ALX04_RS14765 400fd71f82d9fcd601c4df8a2c242ea6 442 SUPERFAMILY SSF54826 3 138 8.25E-59 T 28-03-2018 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 ALX04_RS14765 400fd71f82d9fcd601c4df8a2c242ea6 442 SMART SM01192 139 430 1.9E-218 T 28-03-2018 IPR020810 Enolase, C-terminal TIM barrel domain KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 ALX04_RS00115 0ddf68bf8a951984dafd8e3564a257ee 189 Gene3D G3DSA:3.40.630.30 1 189 8.4E-31 T 28-03-2018 ALX04_RS00115 0ddf68bf8a951984dafd8e3564a257ee 189 Pfam PF00583 Acetyltransferase (GNAT) family 60 168 5.6E-13 T 28-03-2018 IPR000182 GNAT domain GO:0008080 ALX04_RS00115 0ddf68bf8a951984dafd8e3564a257ee 189 SUPERFAMILY SSF55729 2 186 2.09E-27 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase ALX04_RS10040 3ad6a1b75875715eba2e627bc5604b5d 876 Pfam PF09261 Alpha mannosidase middle domain 279 354 2.9E-7 T 28-03-2018 IPR015341 Glycoside hydrolase family 38, central domain GO:0004559|GO:0006013 ALX04_RS10040 3ad6a1b75875715eba2e627bc5604b5d 876 Pfam PF01074 Glycosyl hydrolases family 38 N-terminal domain 3 266 8.4E-41 T 28-03-2018 IPR000602 Glycoside hydrolase family 38, N-terminal domain GO:0004559|GO:0006013 ALX04_RS10040 3ad6a1b75875715eba2e627bc5604b5d 876 SMART SM00872 278 356 6.6E-9 T 28-03-2018 IPR015341 Glycoside hydrolase family 38, central domain GO:0004559|GO:0006013 ALX04_RS10040 3ad6a1b75875715eba2e627bc5604b5d 876 SUPERFAMILY SSF88713 2 228 6.74E-45 T 28-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 ALX04_RS10040 3ad6a1b75875715eba2e627bc5604b5d 876 SUPERFAMILY SSF88688 286 374 5.56E-9 T 28-03-2018 IPR028995 Glycoside hydrolase families 57/38, central domain ALX04_RS10040 3ad6a1b75875715eba2e627bc5604b5d 876 SUPERFAMILY SSF74650 381 871 1.1E-23 T 28-03-2018 IPR011013 Galactose mutarotase-like domain GO:0003824|GO:0005975|GO:0030246 ALX04_RS10040 3ad6a1b75875715eba2e627bc5604b5d 876 Pfam PF07748 Glycosyl hydrolases family 38 C-terminal domain 384 643 1.4E-5 T 28-03-2018 IPR011682 Glycosyl hydrolase family 38, C-terminal GO:0004559|GO:0006013 ALX04_RS10040 3ad6a1b75875715eba2e627bc5604b5d 876 Gene3D G3DSA:1.20.1270.50 277 376 6.5E-15 T 28-03-2018 IPR015341 Glycoside hydrolase family 38, central domain GO:0004559|GO:0006013 ALX04_RS10040 3ad6a1b75875715eba2e627bc5604b5d 876 Gene3D G3DSA:3.20.110.10 1 264 6.4E-49 T 28-03-2018 IPR027291 Glycoside hydrolase 38/57, N-terminal domain ALX04_RS10040 3ad6a1b75875715eba2e627bc5604b5d 876 Gene3D G3DSA:2.60.40.1180 377 501 4.3E-5 T 28-03-2018 ALX04_RS14955 90636ddbaf33965d559787ee4ae9f6eb 508 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 5 252 5.8E-84 T 28-03-2018 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 ALX04_RS14955 90636ddbaf33965d559787ee4ae9f6eb 508 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 262 450 9.3E-54 T 28-03-2018 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 ALX04_RS14955 90636ddbaf33965d559787ee4ae9f6eb 508 Hamap MF_00186 Glycerol kinase [glpK]. 3 497 55.785 T 28-03-2018 IPR005999 Glycerol kinase GO:0004370|GO:0006072 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261|Reactome: R-HSA-75109 ALX04_RS14955 90636ddbaf33965d559787ee4ae9f6eb 508 PIRSF PIRSF000538 3 499 8.6E-165 T 28-03-2018 IPR000577 Carbohydrate kinase, FGGY GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 ALX04_RS14955 90636ddbaf33965d559787ee4ae9f6eb 508 Gene3D G3DSA:3.30.420.40 249 503 5.3E-72 T 28-03-2018 ALX04_RS14955 90636ddbaf33965d559787ee4ae9f6eb 508 TIGRFAM TIGR01311 glycerol_kin: glycerol kinase 4 493 5.7E-218 T 28-03-2018 IPR005999 Glycerol kinase GO:0004370|GO:0006072 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261|Reactome: R-HSA-75109 ALX04_RS14955 90636ddbaf33965d559787ee4ae9f6eb 508 Gene3D G3DSA:3.30.420.40 1 248 3.1E-87 T 28-03-2018 ALX04_RS14955 90636ddbaf33965d559787ee4ae9f6eb 508 SUPERFAMILY SSF53067 254 493 9.18E-79 T 28-03-2018 ALX04_RS14955 90636ddbaf33965d559787ee4ae9f6eb 508 ProSitePatterns PS00933 FGGY family of carbohydrate kinases signature 1. 135 147 - T 28-03-2018 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 ALX04_RS14955 90636ddbaf33965d559787ee4ae9f6eb 508 ProSitePatterns PS00445 FGGY family of carbohydrate kinases signature 2. 362 382 - T 28-03-2018 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 ALX04_RS14955 90636ddbaf33965d559787ee4ae9f6eb 508 SUPERFAMILY SSF53067 4 254 5.1E-95 T 28-03-2018 ALX04_RS03100 f3a12fbeff9153675bf8df8f1abf9ba9 352 Hamap MF_01820 Putative ribosome biogenesis GTPase RsgA [rsgA]. 25 321 32.68 T 28-03-2018 IPR004881 Ribosome biogenesis GTPase RsgA GO:0003924|GO:0005525 ALX04_RS03100 f3a12fbeff9153675bf8df8f1abf9ba9 352 Gene3D G3DSA:3.40.50.300 102 258 3.9E-28 T 28-03-2018 ALX04_RS03100 f3a12fbeff9153675bf8df8f1abf9ba9 352 Gene3D G3DSA:1.10.40.50 259 326 3.3E-22 T 28-03-2018 ALX04_RS03100 f3a12fbeff9153675bf8df8f1abf9ba9 352 TIGRFAM TIGR00157 TIGR00157: ribosome small subunit-dependent GTPase A 67 313 3.9E-48 T 28-03-2018 IPR004881 Ribosome biogenesis GTPase RsgA GO:0003924|GO:0005525 ALX04_RS03100 f3a12fbeff9153675bf8df8f1abf9ba9 352 Gene3D G3DSA:2.40.50.140 18 88 8.4E-10 T 28-03-2018 ALX04_RS03100 f3a12fbeff9153675bf8df8f1abf9ba9 352 Pfam PF03193 RsgA GTPase 87 259 6.9E-50 T 28-03-2018 IPR010914 RsgA GTPase domain GO:0003924|GO:0005525 ALX04_RS03100 f3a12fbeff9153675bf8df8f1abf9ba9 352 SUPERFAMILY SSF52540 104 319 2.12E-51 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase ALX04_RS04355 e2c3aa26f6d8137494b78de7cd67cb97 302 Gene3D G3DSA:3.30.300.20 196 300 2.0E-46 T 28-03-2018 IPR015946 K homology domain-like, alpha/beta ALX04_RS04355 e2c3aa26f6d8137494b78de7cd67cb97 302 Pfam PF07650 KH domain 209 285 2.0E-22 T 28-03-2018 IPR004044 K Homology domain, type 2 GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 ALX04_RS04355 e2c3aa26f6d8137494b78de7cd67cb97 302 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 12 32 8.0E-6 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 ALX04_RS04355 e2c3aa26f6d8137494b78de7cd67cb97 302 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 79 97 8.0E-6 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 ALX04_RS04355 e2c3aa26f6d8137494b78de7cd67cb97 302 Gene3D G3DSA:1.20.120.430 1 64 2.6E-18 T 28-03-2018 ALX04_RS04355 e2c3aa26f6d8137494b78de7cd67cb97 302 SUPERFAMILY SSF52540 12 206 5.9E-49 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase ALX04_RS04355 e2c3aa26f6d8137494b78de7cd67cb97 302 Hamap MF_00367 GTPase Era [era]. 7 297 38.528 T 28-03-2018 IPR005662 GTP-binding protein Era GO:0003723|GO:0005525|GO:0005622 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 ALX04_RS04355 e2c3aa26f6d8137494b78de7cd67cb97 302 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 11 168 5.2E-27 T 28-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 ALX04_RS04355 e2c3aa26f6d8137494b78de7cd67cb97 302 Gene3D G3DSA:3.40.50.300 65 195 1.2E-15 T 28-03-2018 ALX04_RS04355 e2c3aa26f6d8137494b78de7cd67cb97 302 SUPERFAMILY SSF54814 183 298 2.09E-42 T 28-03-2018 IPR009019 K homology domain, prokaryotic type GO:0003723 ALX04_RS04355 e2c3aa26f6d8137494b78de7cd67cb97 302 TIGRFAM TIGR00436 era: GTP-binding protein Era 10 280 1.9E-105 T 28-03-2018 IPR005662 GTP-binding protein Era GO:0003723|GO:0005525|GO:0005622 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 ALX04_RS04355 e2c3aa26f6d8137494b78de7cd67cb97 302 Pfam PF01926 50S ribosome-binding GTPase 12 126 3.6E-24 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 ALX04_RS06020 225ccf4591bfcf4d167c907fd6a6285a 447 SUPERFAMILY SSF52540 72 354 7.16E-64 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase ALX04_RS06020 225ccf4591bfcf4d167c907fd6a6285a 447 Pfam PF00271 Helicase conserved C-terminal domain 230 339 2.3E-26 T 28-03-2018 IPR001650 Helicase, C-terminal ALX04_RS06020 225ccf4591bfcf4d167c907fd6a6285a 447 SMART SM00487 22 222 3.8E-47 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain ALX04_RS06020 225ccf4591bfcf4d167c907fd6a6285a 447 Gene3D G3DSA:3.40.50.300 215 447 2.8E-43 T 28-03-2018 ALX04_RS06020 225ccf4591bfcf4d167c907fd6a6285a 447 Pfam PF00270 DEAD/DEAH box helicase 27 193 4.7E-38 T 28-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 ALX04_RS06020 225ccf4591bfcf4d167c907fd6a6285a 447 SMART SM00490 258 339 6.4E-29 T 28-03-2018 IPR001650 Helicase, C-terminal ALX04_RS06020 225ccf4591bfcf4d167c907fd6a6285a 447 Gene3D G3DSA:3.40.50.300 6 214 7.4E-48 T 28-03-2018 ALX04_RS06020 225ccf4591bfcf4d167c907fd6a6285a 447 Hamap MF_01494 DEAD-box ATP-dependent RNA helicase CshB [cshB]. 3 437 51.553 T 28-03-2018 IPR030881 DEAD-box ATP-dependent RNA helicase CshB GO:0004386|GO:0009409 ALX04_RS05315 8e2fbb6d0b282bd098b1ad9df9d5ccf1 257 ProSitePatterns PS00629 Inositol monophosphatase family signature 1. 86 99 - T 28-03-2018 IPR020583 Inositol monophosphatase, metal-binding site ALX04_RS05315 8e2fbb6d0b282bd098b1ad9df9d5ccf1 257 Gene3D G3DSA:3.40.190.80 153 257 1.7E-14 T 28-03-2018 ALX04_RS05315 8e2fbb6d0b282bd098b1ad9df9d5ccf1 257 Pfam PF00459 Inositol monophosphatase family 19 255 6.3E-41 T 28-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 ALX04_RS05315 8e2fbb6d0b282bd098b1ad9df9d5ccf1 257 Gene3D G3DSA:3.30.540.10 2 145 1.4E-31 T 28-03-2018 ALX04_RS05315 8e2fbb6d0b282bd098b1ad9df9d5ccf1 257 PRINTS PR00377 Inositol monophosphatase superfamily signature 64 80 4.8E-24 T 28-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 ALX04_RS05315 8e2fbb6d0b282bd098b1ad9df9d5ccf1 257 PRINTS PR00377 Inositol monophosphatase superfamily signature 207 231 4.8E-24 T 28-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 ALX04_RS05315 8e2fbb6d0b282bd098b1ad9df9d5ccf1 257 PRINTS PR00377 Inositol monophosphatase superfamily signature 135 158 4.8E-24 T 28-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 ALX04_RS05315 8e2fbb6d0b282bd098b1ad9df9d5ccf1 257 PRINTS PR00377 Inositol monophosphatase superfamily signature 42 62 4.8E-24 T 28-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 ALX04_RS05315 8e2fbb6d0b282bd098b1ad9df9d5ccf1 257 PRINTS PR00377 Inositol monophosphatase superfamily signature 86 102 4.8E-24 T 28-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 ALX04_RS05315 8e2fbb6d0b282bd098b1ad9df9d5ccf1 257 PRINTS PR00377 Inositol monophosphatase superfamily signature 177 198 4.8E-24 T 28-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 ALX04_RS05315 8e2fbb6d0b282bd098b1ad9df9d5ccf1 257 SUPERFAMILY SSF56655 16 256 4.06E-53 T 28-03-2018 ALX04_RS13490 709dfb2edc01f50c15d2b4384e932cf2 305 Gene3D G3DSA:3.30.420.40 1 117 2.2E-36 T 28-03-2018 ALX04_RS13490 709dfb2edc01f50c15d2b4384e932cf2 305 Pfam PF02541 Ppx/GppA phosphatase family 23 303 3.2E-53 T 28-03-2018 IPR003695 Ppx/GppA phosphatase KEGG: 00230+3.6.1.40 ALX04_RS13490 709dfb2edc01f50c15d2b4384e932cf2 305 SUPERFAMILY SSF53067 129 305 8.63E-35 T 28-03-2018 ALX04_RS13490 709dfb2edc01f50c15d2b4384e932cf2 305 Gene3D G3DSA:3.30.420.150 118 301 3.3E-35 T 28-03-2018 ALX04_RS13490 709dfb2edc01f50c15d2b4384e932cf2 305 SUPERFAMILY SSF53067 4 124 8.09E-31 T 28-03-2018 ALX04_RS08760 22917dd9fe2fbd9a2ce6bc4bfb66c1d9 1106 TIGRFAM TIGR03062 pip_yhgE_Cterm: YhgE/Pip C-terminal domain 884 1087 5.5E-66 T 28-03-2018 IPR017501 Phage infection protein, YhgE, C-terminal ALX04_RS08760 22917dd9fe2fbd9a2ce6bc4bfb66c1d9 1106 Gene3D G3DSA:3.90.20.10 445 592 0.0077 T 28-03-2018 ALX04_RS08760 22917dd9fe2fbd9a2ce6bc4bfb66c1d9 1106 SUPERFAMILY SSF58104 583 836 7.85E-7 T 28-03-2018 ALX04_RS08760 22917dd9fe2fbd9a2ce6bc4bfb66c1d9 1106 ProDom PD936484 POLYPROTEIN GLYCOPROTEIN M G2 TRANSMEMBRANE NONSTRUCTURAL MEMBRANE CONTAINS: PRECURSOR SIGNAL 502 689 0.001 T 28-03-2018 ALX04_RS08760 22917dd9fe2fbd9a2ce6bc4bfb66c1d9 1106 Gene3D G3DSA:1.20.120.570 314 441 1.5E-11 T 28-03-2018 ALX04_RS08760 22917dd9fe2fbd9a2ce6bc4bfb66c1d9 1106 Gene3D G3DSA:1.20.120.570 593 693 7.5E-18 T 28-03-2018 ALX04_RS08760 22917dd9fe2fbd9a2ce6bc4bfb66c1d9 1106 TIGRFAM TIGR03057 xxxLxxG_by_4: X-X-X-Leu-X-X-Gly heptad repeats 832 859 1.2E-4 T 28-03-2018 IPR023908 xxxLxxG heptad repeat ALX04_RS08760 22917dd9fe2fbd9a2ce6bc4bfb66c1d9 1106 TIGRFAM TIGR03057 xxxLxxG_by_4: X-X-X-Leu-X-X-Gly heptad repeats 263 290 1.1E-6 T 28-03-2018 IPR023908 xxxLxxG heptad repeat ALX04_RS08760 22917dd9fe2fbd9a2ce6bc4bfb66c1d9 1106 TIGRFAM TIGR03057 xxxLxxG_by_4: X-X-X-Leu-X-X-Gly heptad repeats 755 782 2.0E-6 T 28-03-2018 IPR023908 xxxLxxG heptad repeat ALX04_RS08760 22917dd9fe2fbd9a2ce6bc4bfb66c1d9 1106 TIGRFAM TIGR03057 xxxLxxG_by_4: X-X-X-Leu-X-X-Gly heptad repeats 615 640 1.8E-4 T 28-03-2018 IPR023908 xxxLxxG heptad repeat ALX04_RS08760 22917dd9fe2fbd9a2ce6bc4bfb66c1d9 1106 TIGRFAM TIGR03057 xxxLxxG_by_4: X-X-X-Leu-X-X-Gly heptad repeats 783 810 5.9E-7 T 28-03-2018 IPR023908 xxxLxxG heptad repeat ALX04_RS08760 22917dd9fe2fbd9a2ce6bc4bfb66c1d9 1106 TIGRFAM TIGR03057 xxxLxxG_by_4: X-X-X-Leu-X-X-Gly heptad repeats 811 838 2.0E-6 T 28-03-2018 IPR023908 xxxLxxG heptad repeat ALX04_RS08760 22917dd9fe2fbd9a2ce6bc4bfb66c1d9 1106 TIGRFAM TIGR03057 xxxLxxG_by_4: X-X-X-Leu-X-X-Gly heptad repeats 707 733 1.8E-4 T 28-03-2018 IPR023908 xxxLxxG heptad repeat ALX04_RS08760 22917dd9fe2fbd9a2ce6bc4bfb66c1d9 1106 TIGRFAM TIGR03057 xxxLxxG_by_4: X-X-X-Leu-X-X-Gly heptad repeats 236 262 2.5E-5 T 28-03-2018 IPR023908 xxxLxxG heptad repeat ALX04_RS08760 22917dd9fe2fbd9a2ce6bc4bfb66c1d9 1106 TIGRFAM TIGR03057 xxxLxxG_by_4: X-X-X-Leu-X-X-Gly heptad repeats 291 318 4.2E-6 T 28-03-2018 IPR023908 xxxLxxG heptad repeat ALX04_RS08760 22917dd9fe2fbd9a2ce6bc4bfb66c1d9 1106 TIGRFAM TIGR03057 xxxLxxG_by_4: X-X-X-Leu-X-X-Gly heptad repeats 208 234 4.9E-5 T 28-03-2018 IPR023908 xxxLxxG heptad repeat ALX04_RS08760 22917dd9fe2fbd9a2ce6bc4bfb66c1d9 1106 Pfam PF12698 ABC-2 family transporter protein 19 148 1.1E-13 T 28-03-2018 ALX04_RS08760 22917dd9fe2fbd9a2ce6bc4bfb66c1d9 1106 Gene3D G3DSA:1.10.287.1060 810 886 1.4E-4 T 28-03-2018 ALX04_RS08760 22917dd9fe2fbd9a2ce6bc4bfb66c1d9 1106 Gene3D G3DSA:1.10.287.950 714 789 2.0E-6 T 28-03-2018 ALX04_RS08760 22917dd9fe2fbd9a2ce6bc4bfb66c1d9 1106 TIGRFAM TIGR03061 pip_yhgE_Nterm: YhgE/Pip N-terminal domain 7 169 2.1E-65 T 28-03-2018 IPR017500 Phage infection protein, YhgE, N-terminal ALX04_RS08760 22917dd9fe2fbd9a2ce6bc4bfb66c1d9 1106 Gene3D G3DSA:1.20.5.300 790 809 0.11 T 28-03-2018 ALX04_RS08760 22917dd9fe2fbd9a2ce6bc4bfb66c1d9 1106 Gene3D G3DSA:1.20.5.300 694 713 0.11 T 28-03-2018 ALX04_RS08760 22917dd9fe2fbd9a2ce6bc4bfb66c1d9 1106 Gene3D G3DSA:1.20.5.300 203 231 0.003 T 28-03-2018 ALX04_RS08760 22917dd9fe2fbd9a2ce6bc4bfb66c1d9 1106 Gene3D G3DSA:3.40.1710.10 44 202 4.0E-27 T 28-03-2018 ALX04_RS08760 22917dd9fe2fbd9a2ce6bc4bfb66c1d9 1106 Gene3D G3DSA:1.10.287.950 235 313 2.0E-6 T 28-03-2018 ALX04_RS06765 d1cd54371fe487e64e34b0c667bfa1b3 290 Pfam PF12684 PDDEXK-like domain of unknown function (DUF3799) 43 275 9.2E-87 T 28-03-2018 IPR024432 Putative exodeoxyribonuclease 8, PDDEXK-like domain ALX04_RS06765 d1cd54371fe487e64e34b0c667bfa1b3 290 Gene3D G3DSA:3.90.320.10 31 224 4.5E-5 T 28-03-2018 IPR011604 Exonuclease, phage-type/RecB, C-terminal GO:0003677|GO:0004518 ALX04_RS06765 d1cd54371fe487e64e34b0c667bfa1b3 290 PIRSF PIRSF031475 23 287 5.3E-117 T 28-03-2018 IPR016974 Uncharacterised phage-associated protein ALX04_RS06350 8a253361f1cbcaf57aab0766d6eb1738 305 SUPERFAMILY SSF51735 1 147 1.16E-38 T 28-03-2018 IPR016040 NAD(P)-binding domain ALX04_RS06350 8a253361f1cbcaf57aab0766d6eb1738 305 Gene3D G3DSA:3.40.50.720 5 146 3.0E-23 T 28-03-2018 ALX04_RS06350 8a253361f1cbcaf57aab0766d6eb1738 305 PRINTS PR00086 L-lactate dehydrogenase signature 3 27 7.8E-28 T 28-03-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 ALX04_RS06350 8a253361f1cbcaf57aab0766d6eb1738 305 PRINTS PR00086 L-lactate dehydrogenase signature 143 161 7.8E-28 T 28-03-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 ALX04_RS06350 8a253361f1cbcaf57aab0766d6eb1738 305 PRINTS PR00086 L-lactate dehydrogenase signature 119 139 7.8E-28 T 28-03-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 ALX04_RS06350 8a253361f1cbcaf57aab0766d6eb1738 305 PRINTS PR00086 L-lactate dehydrogenase signature 173 186 7.8E-28 T 28-03-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 ALX04_RS06350 8a253361f1cbcaf57aab0766d6eb1738 305 PRINTS PR00086 L-lactate dehydrogenase signature 28 52 7.8E-28 T 28-03-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 ALX04_RS06350 8a253361f1cbcaf57aab0766d6eb1738 305 Pfam PF00056 lactate/malate dehydrogenase, NAD binding domain 5 145 1.4E-22 T 28-03-2018 IPR001236 Lactate/malate dehydrogenase, N-terminal GO:0016491|GO:0055114 ALX04_RS06350 8a253361f1cbcaf57aab0766d6eb1738 305 Gene3D G3DSA:3.90.110.10 147 303 5.4E-34 T 28-03-2018 ALX04_RS06350 8a253361f1cbcaf57aab0766d6eb1738 305 SUPERFAMILY SSF56327 146 301 2.31E-41 T 28-03-2018 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 ALX04_RS06350 8a253361f1cbcaf57aab0766d6eb1738 305 Pfam PF02866 lactate/malate dehydrogenase, alpha/beta C-terminal domain 148 300 2.6E-13 T 28-03-2018 IPR022383 Lactate/malate dehydrogenase, C-terminal GO:0016616|GO:0055114 ALX04_RS06350 8a253361f1cbcaf57aab0766d6eb1738 305 PIRSF PIRSF000102 1 304 4.0E-84 T 28-03-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 ALX04_RS14710 709cf49869b1b323b778e9b84eb6c0e7 333 Gene3D G3DSA:3.40.50.10680 90 332 1.8E-54 T 28-03-2018 ALX04_RS14710 709cf49869b1b323b778e9b84eb6c0e7 333 TIGRFAM TIGR01826 CofD_related: conserved hypothetical protein 13 325 8.5E-114 T 28-03-2018 IPR010119 Gluconeogenesis factor ALX04_RS14710 709cf49869b1b323b778e9b84eb6c0e7 333 Pfam PF01933 Uncharacterised protein family UPF0052 13 303 6.1E-97 T 28-03-2018 IPR002882 LPPG:FO 2-phospho-L-lactate transferase CofD/UPF0052 ALX04_RS14710 709cf49869b1b323b778e9b84eb6c0e7 333 Hamap MF_00973 Gluconeogenesis factor. 9 328 32.942 T 28-03-2018 IPR010119 Gluconeogenesis factor ALX04_RS14710 709cf49869b1b323b778e9b84eb6c0e7 333 SUPERFAMILY SSF142338 10 323 1.57E-99 T 28-03-2018 ALX04_RS03700 eb25432cedcd8b6e79bde204907ee619 449 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 6 25 9.9E-27 T 28-03-2018 ALX04_RS03700 eb25432cedcd8b6e79bde204907ee619 449 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 129 147 9.9E-27 T 28-03-2018 ALX04_RS03700 eb25432cedcd8b6e79bde204907ee619 449 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 278 300 9.9E-27 T 28-03-2018 ALX04_RS03700 eb25432cedcd8b6e79bde204907ee619 449 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 166 184 9.9E-27 T 28-03-2018 ALX04_RS03700 eb25432cedcd8b6e79bde204907ee619 449 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 250 266 9.9E-27 T 28-03-2018 ALX04_RS03700 eb25432cedcd8b6e79bde204907ee619 449 Gene3D G3DSA:3.50.50.60 1 165 2.9E-21 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ALX04_RS03700 eb25432cedcd8b6e79bde204907ee619 449 Gene3D G3DSA:3.40.50.720 166 320 2.2E-29 T 28-03-2018 ALX04_RS03700 eb25432cedcd8b6e79bde204907ee619 449 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 5 27 2.0E-39 T 28-03-2018 ALX04_RS03700 eb25432cedcd8b6e79bde204907ee619 449 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 166 191 2.0E-39 T 28-03-2018 ALX04_RS03700 eb25432cedcd8b6e79bde204907ee619 449 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 330 351 2.0E-39 T 28-03-2018 ALX04_RS03700 eb25432cedcd8b6e79bde204907ee619 449 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 132 141 2.0E-39 T 28-03-2018 ALX04_RS03700 eb25432cedcd8b6e79bde204907ee619 449 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 251 265 2.0E-39 T 28-03-2018 ALX04_RS03700 eb25432cedcd8b6e79bde204907ee619 449 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 293 300 2.0E-39 T 28-03-2018 ALX04_RS03700 eb25432cedcd8b6e79bde204907ee619 449 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 394 409 2.0E-39 T 28-03-2018 ALX04_RS03700 eb25432cedcd8b6e79bde204907ee619 449 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 37 52 2.0E-39 T 28-03-2018 ALX04_RS03700 eb25432cedcd8b6e79bde204907ee619 449 PIRSF PIRSF000350 1 439 4.6E-61 T 28-03-2018 ALX04_RS03700 eb25432cedcd8b6e79bde204907ee619 449 SUPERFAMILY SSF51905 1 357 1.53E-46 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ALX04_RS03700 eb25432cedcd8b6e79bde204907ee619 449 Gene3D G3DSA:3.30.390.30 321 443 6.0E-18 T 28-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 ALX04_RS03700 eb25432cedcd8b6e79bde204907ee619 449 SUPERFAMILY SSF55424 331 443 3.78E-20 T 28-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 ALX04_RS03700 eb25432cedcd8b6e79bde204907ee619 449 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 4 312 1.2E-52 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ALX04_RS03700 eb25432cedcd8b6e79bde204907ee619 449 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 334 435 7.7E-11 T 28-03-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 ALX04_RS02725 41df2753fb730a5433dd72cd33d270c4 447 Hamap MF_00378 Exodeoxyribonuclease 7 large subunit [xseA]. 5 441 28.911 T 28-03-2018 IPR003753 Exonuclease VII, large subunit GO:0006308|GO:0008855|GO:0009318 ALX04_RS02725 41df2753fb730a5433dd72cd33d270c4 447 Gene3D G3DSA:3.40.50.1970 109 245 2.2E-4 T 28-03-2018 ALX04_RS02725 41df2753fb730a5433dd72cd33d270c4 447 Pfam PF02601 Exonuclease VII, large subunit 130 438 6.0E-100 T 28-03-2018 IPR020579 Exonuclease VII, large subunit, C-terminal GO:0008855 ALX04_RS02725 41df2753fb730a5433dd72cd33d270c4 447 TIGRFAM TIGR00237 xseA: exodeoxyribonuclease VII, large subunit 9 352 1.3E-133 T 28-03-2018 IPR003753 Exonuclease VII, large subunit GO:0006308|GO:0008855|GO:0009318 ALX04_RS02725 41df2753fb730a5433dd72cd33d270c4 447 Gene3D G3DSA:2.40.50.140 15 104 5.2E-7 T 28-03-2018 ALX04_RS02725 41df2753fb730a5433dd72cd33d270c4 447 Pfam PF13742 OB-fold nucleic acid binding domain 8 103 3.7E-28 T 28-03-2018 IPR025824 OB-fold nucleic acid binding domain GO:0003676 ALX04_RS14825 99f1423d882fba15d886c822bc51a123 289 Gene3D G3DSA:3.40.50.1000 1 289 2.8E-38 T 28-03-2018 IPR023214 HAD-like domain ALX04_RS14825 99f1423d882fba15d886c822bc51a123 289 TIGRFAM TIGR00099 Cof-subfamily: Cof-like hydrolase 4 282 2.0E-59 T 28-03-2018 IPR000150 Cof family GO:0016787 ALX04_RS14825 99f1423d882fba15d886c822bc51a123 289 ProSitePatterns PS01228 Hypothetical cof family signature 1. 4 15 - T 28-03-2018 ALX04_RS14825 99f1423d882fba15d886c822bc51a123 289 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 4 255 1.0E-22 T 28-03-2018 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 ALX04_RS14825 99f1423d882fba15d886c822bc51a123 289 ProSitePatterns PS01229 Hypothetical cof family signature 2. 236 258 - T 28-03-2018 ALX04_RS14825 99f1423d882fba15d886c822bc51a123 289 Pfam PF08282 haloacid dehalogenase-like hydrolase 5 282 3.6E-64 T 28-03-2018 IPR023214 HAD-like domain ALX04_RS14825 99f1423d882fba15d886c822bc51a123 289 SUPERFAMILY SSF56784 1 286 1.74E-67 T 28-03-2018 IPR023214 HAD-like domain ALX04_RS10210 c3fb5313ead7d07161e34420d93c4789 244 Pfam PF00440 Bacterial regulatory proteins, tetR family 31 74 1.0E-10 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 ALX04_RS10210 c3fb5313ead7d07161e34420d93c4789 244 SUPERFAMILY SSF46689 21 81 5.13E-12 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 ALX04_RS10210 c3fb5313ead7d07161e34420d93c4789 244 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 30 43 2.0E-6 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 ALX04_RS10210 c3fb5313ead7d07161e34420d93c4789 244 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 51 74 2.0E-6 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 ALX04_RS10210 c3fb5313ead7d07161e34420d93c4789 244 Gene3D G3DSA:1.10.10.60 21 63 1.6E-9 T 28-03-2018 ALX04_RS10210 c3fb5313ead7d07161e34420d93c4789 244 Gene3D G3DSA:1.10.10.60 64 195 5.3E-6 T 28-03-2018 ALX04_RS11910 db10b9af89b27d088be5fa191d94fd0b 334 Gene3D G3DSA:3.40.50.720 139 315 4.7E-30 T 28-03-2018 ALX04_RS11910 db10b9af89b27d088be5fa191d94fd0b 334 Pfam PF13602 Zinc-binding dehydrogenase 186 329 4.4E-30 T 28-03-2018 ALX04_RS11910 db10b9af89b27d088be5fa191d94fd0b 334 SUPERFAMILY SSF51735 116 262 2.37E-37 T 28-03-2018 IPR016040 NAD(P)-binding domain ALX04_RS11910 db10b9af89b27d088be5fa191d94fd0b 334 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 27 87 1.0E-9 T 28-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 ALX04_RS11910 db10b9af89b27d088be5fa191d94fd0b 334 SUPERFAMILY SSF50129 1 147 1.07E-36 T 28-03-2018 IPR011032 GroES-like ALX04_RS11910 db10b9af89b27d088be5fa191d94fd0b 334 SMART SM00829 11 329 1.3E-20 T 28-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 ALX04_RS11910 db10b9af89b27d088be5fa191d94fd0b 334 Gene3D G3DSA:3.90.180.10 1 138 8.4E-42 T 28-03-2018 ALX04_RS05030 5abdbeb04abbece77cdba77ebd1c64b5 387 Pfam PF14659 Phage integrase, N-terminal SAM-like domain 63 117 2.6E-7 T 28-03-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 ALX04_RS05030 5abdbeb04abbece77cdba77ebd1c64b5 387 Gene3D G3DSA:1.10.150.130 56 180 6.8E-11 T 28-03-2018 IPR023109 Integrase/recombinase, N-terminal ALX04_RS05030 5abdbeb04abbece77cdba77ebd1c64b5 387 Gene3D G3DSA:1.10.443.10 184 375 1.3E-35 T 28-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 ALX04_RS05030 5abdbeb04abbece77cdba77ebd1c64b5 387 SUPERFAMILY SSF56349 63 374 1.91E-56 T 28-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 ALX04_RS05030 5abdbeb04abbece77cdba77ebd1c64b5 387 Pfam PF14657 Arm DNA-binding domain 10 48 2.9E-8 T 28-03-2018 IPR028259 AP2-like integrase, N-terminal domain ALX04_RS05030 5abdbeb04abbece77cdba77ebd1c64b5 387 Pfam PF00589 Phage integrase family 184 367 1.2E-27 T 28-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 ALX04_RS01610 de77c692246cd071d1d45e85c9305061 2418 TIGRFAM TIGR03715 KxYKxGKxW: KxYKxGKxW signal peptide 15 36 1.0E-6 T 28-03-2018 IPR022263 KxYKxGKxW signal peptide ALX04_RS01610 de77c692246cd071d1d45e85c9305061 2418 SUPERFAMILY SSF49373 778 842 1.1E-9 T 28-03-2018 IPR008964 Invasin/intimin cell-adhesion fragments ALX04_RS01610 de77c692246cd071d1d45e85c9305061 2418 SMART SM00409 822 943 0.0086 T 28-03-2018 IPR003599 Immunoglobulin subtype ALX04_RS01610 de77c692246cd071d1d45e85c9305061 2418 SMART SM00635 764 849 2.0E-7 T 28-03-2018 IPR003343 Bacterial Ig-like, group 2 ALX04_RS13430 c7c27bc1ce1d152ef955c64182432c51 769 Gene3D G3DSA:3.40.50.300 595 767 2.2E-22 T 28-03-2018 ALX04_RS13430 c7c27bc1ce1d152ef955c64182432c51 769 SUPERFAMILY SSF52540 358 386 1.23E-52 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase ALX04_RS13430 c7c27bc1ce1d152ef955c64182432c51 769 SUPERFAMILY SSF52540 204 330 1.23E-52 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase ALX04_RS13430 c7c27bc1ce1d152ef955c64182432c51 769 SUPERFAMILY SSF52540 485 749 1.23E-52 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase ALX04_RS13430 c7c27bc1ce1d152ef955c64182432c51 769 Pfam PF13538 UvrD-like helicase C-terminal domain 696 743 7.4E-8 T 28-03-2018 IPR027785 UvrD-like helicase C-terminal domain ALX04_RS13430 c7c27bc1ce1d152ef955c64182432c51 769 Gene3D G3DSA:3.40.50.300 210 591 5.8E-26 T 28-03-2018 ALX04_RS11180 d54db7fd13da6073450ce7098a2b404b 666 Gene3D G3DSA:2.70.70.10 507 666 4.0E-60 T 28-03-2018 ALX04_RS11180 d54db7fd13da6073450ce7098a2b404b 666 SUPERFAMILY SSF51261 514 660 3.66E-55 T 28-03-2018 IPR011055 Duplicated hybrid motif ALX04_RS11180 d54db7fd13da6073450ce7098a2b404b 666 Gene3D G3DSA:3.30.1360.60 3 77 5.4E-27 T 28-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 ALX04_RS11180 d54db7fd13da6073450ce7098a2b404b 666 Pfam PF00358 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 518 642 8.9E-53 T 28-03-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 ALX04_RS11180 d54db7fd13da6073450ce7098a2b404b 666 ProSitePatterns PS01035 PTS EIIB domains cysteine phosphorylation site signature. 20 37 - T 28-03-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 ALX04_RS11180 d54db7fd13da6073450ce7098a2b404b 666 SUPERFAMILY SSF55604 7 80 3.92E-21 T 28-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 ALX04_RS11180 d54db7fd13da6073450ce7098a2b404b 666 TIGRFAM TIGR00830 PTBA: PTS system, glucose subfamily, IIA component 520 639 5.6E-45 T 28-03-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 ALX04_RS11180 d54db7fd13da6073450ce7098a2b404b 666 Pfam PF02378 Phosphotransferase system, EIIC 111 404 5.1E-32 T 28-03-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 ALX04_RS11180 d54db7fd13da6073450ce7098a2b404b 666 Pfam PF00367 phosphotransferase system, EIIB 9 40 1.8E-14 T 28-03-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 ALX04_RS11180 d54db7fd13da6073450ce7098a2b404b 666 TIGRFAM TIGR01995 PTS-II-ABC-beta: PTS system, beta-glucoside-specific IIABC component 4 664 3.5E-223 T 28-03-2018 IPR011297 Phosphotransferase system, beta-glucoside-specific IIABC component GO:0005886|GO:0008982|GO:0009401 ALX04_RS11180 d54db7fd13da6073450ce7098a2b404b 666 ProSitePatterns PS00371 PTS EIIA domains phosphorylation site signature 1. 581 593 - T 28-03-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 ALX04_RS13165 34a2b5068a667d884e69be8ef6fbc8fc 303 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 168 185 1.2E-27 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR ALX04_RS13165 34a2b5068a667d884e69be8ef6fbc8fc 303 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 6 23 1.2E-27 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR ALX04_RS13165 34a2b5068a667d884e69be8ef6fbc8fc 303 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 74 85 1.2E-27 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR ALX04_RS13165 34a2b5068a667d884e69be8ef6fbc8fc 303 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 121 137 1.2E-27 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR ALX04_RS13165 34a2b5068a667d884e69be8ef6fbc8fc 303 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 147 166 1.2E-27 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR ALX04_RS13165 34a2b5068a667d884e69be8ef6fbc8fc 303 Gene3D G3DSA:3.40.50.720 4 256 2.8E-62 T 28-03-2018 ALX04_RS13165 34a2b5068a667d884e69be8ef6fbc8fc 303 SUPERFAMILY SSF51735 4 246 6.96E-63 T 28-03-2018 IPR016040 NAD(P)-binding domain ALX04_RS13165 34a2b5068a667d884e69be8ef6fbc8fc 303 Pfam PF00106 short chain dehydrogenase 6 185 6.5E-48 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR ALX04_RS13165 34a2b5068a667d884e69be8ef6fbc8fc 303 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 147 166 3.5E-11 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR ALX04_RS13165 34a2b5068a667d884e69be8ef6fbc8fc 303 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 127 135 3.5E-11 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR ALX04_RS13165 34a2b5068a667d884e69be8ef6fbc8fc 303 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 74 85 3.5E-11 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR ALX04_RS04480 b04408794972f3fb0a574b996947af06 611 SUPERFAMILY SSF54980 301 379 2.63E-18 T 28-03-2018 IPR035647 EF-G domain III/V-like ALX04_RS04480 b04408794972f3fb0a574b996947af06 611 Pfam PF00679 Elongation factor G C-terminus 408 494 2.6E-24 T 28-03-2018 IPR000640 Elongation factor EFG, domain V-like ALX04_RS04480 b04408794972f3fb0a574b996947af06 611 PRINTS PR00315 GTP-binding elongation factor signature 135 144 3.1E-14 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 ALX04_RS04480 b04408794972f3fb0a574b996947af06 611 PRINTS PR00315 GTP-binding elongation factor signature 83 93 3.1E-14 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 ALX04_RS04480 b04408794972f3fb0a574b996947af06 611 PRINTS PR00315 GTP-binding elongation factor signature 99 110 3.1E-14 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 ALX04_RS04480 b04408794972f3fb0a574b996947af06 611 PRINTS PR00315 GTP-binding elongation factor signature 15 28 3.1E-14 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 ALX04_RS04480 b04408794972f3fb0a574b996947af06 611 PRINTS PR00315 GTP-binding elongation factor signature 58 66 3.1E-14 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 ALX04_RS04480 b04408794972f3fb0a574b996947af06 611 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 15 183 6.9E-20 T 28-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 ALX04_RS04480 b04408794972f3fb0a574b996947af06 611 Pfam PF03144 Elongation factor Tu domain 2 214 284 6.1E-9 T 28-03-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 ALX04_RS04480 b04408794972f3fb0a574b996947af06 611 SUPERFAMILY SSF54980 408 503 3.26E-26 T 28-03-2018 IPR035647 EF-G domain III/V-like ALX04_RS04480 b04408794972f3fb0a574b996947af06 611 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 51 66 - T 28-03-2018 IPR031157 Tr-type G domain, conserved site ALX04_RS04480 b04408794972f3fb0a574b996947af06 611 Gene3D G3DSA:3.30.70.870 295 376 1.9E-27 T 28-03-2018 ALX04_RS04480 b04408794972f3fb0a574b996947af06 611 Pfam PF06421 GTP-binding protein LepA C-terminus 497 603 1.2E-47 T 28-03-2018 IPR013842 GTP-binding protein LepA, C-terminal ALX04_RS04480 b04408794972f3fb0a574b996947af06 611 Gene3D G3DSA:2.40.30.10 183 288 4.1E-25 T 28-03-2018 ALX04_RS04480 b04408794972f3fb0a574b996947af06 611 Gene3D G3DSA:3.30.70.240 398 558 5.5E-30 T 28-03-2018 ALX04_RS04480 b04408794972f3fb0a574b996947af06 611 Pfam PF00009 Elongation factor Tu GTP binding domain 12 190 6.3E-54 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 ALX04_RS04480 b04408794972f3fb0a574b996947af06 611 Gene3D G3DSA:3.40.50.300 8 182 6.3E-36 T 28-03-2018 ALX04_RS04480 b04408794972f3fb0a574b996947af06 611 TIGRFAM TIGR01393 lepA: elongation factor 4 12 605 2.0E-304 T 28-03-2018 IPR006297 Elongation factor 4 GO:0005525 ALX04_RS04480 b04408794972f3fb0a574b996947af06 611 SUPERFAMILY SSF52540 5 230 7.97E-57 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase ALX04_RS04480 b04408794972f3fb0a574b996947af06 611 Hamap MF_00071 Elongation factor 4 [lepA]. 1 607 300.108 T 28-03-2018 IPR006297 Elongation factor 4 GO:0005525 ALX04_RS04480 b04408794972f3fb0a574b996947af06 611 SMART SM00838 407 495 3.6E-4 T 28-03-2018 IPR000640 Elongation factor EFG, domain V-like ALX04_RS14540 882af39862043f9f92bbf4813095ce23 357 Gene3D G3DSA:3.30.160.20 211 293 2.4E-34 T 28-03-2018 ALX04_RS14540 882af39862043f9f92bbf4813095ce23 357 Pfam PF00472 RF-1 domain 214 323 1.6E-42 T 28-03-2018 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 ALX04_RS14540 882af39862043f9f92bbf4813095ce23 357 Gene3D G3DSA:1.20.58.410 3 108 9.6E-25 T 28-03-2018 ALX04_RS14540 882af39862043f9f92bbf4813095ce23 357 Pfam PF03462 PCRF domain 16 205 1.9E-60 T 28-03-2018 IPR005139 Peptide chain release factor GO:0006415 ALX04_RS14540 882af39862043f9f92bbf4813095ce23 357 Hamap MF_00094 Peptide chain release factor 2 [prfB]. 2 351 39.831 T 28-03-2018 IPR020853 Peptide chain release factor 2, bacterial GO:0005737|GO:0006415|GO:0016149 ALX04_RS14540 882af39862043f9f92bbf4813095ce23 357 SMART SM00937 70 180 2.0E-57 T 28-03-2018 IPR005139 Peptide chain release factor GO:0006415 ALX04_RS14540 882af39862043f9f92bbf4813095ce23 357 ProSitePatterns PS00745 Prokaryotic-type class I peptide chain release factors signature. 230 246 - T 28-03-2018 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 ALX04_RS14540 882af39862043f9f92bbf4813095ce23 357 SUPERFAMILY SSF75620 15 353 2.09E-135 T 28-03-2018 ALX04_RS14540 882af39862043f9f92bbf4813095ce23 357 TIGRFAM TIGR00020 prfB: peptide chain release factor 2 4 350 2.4E-159 T 28-03-2018 IPR004374 Peptide chain release factor 2 GO:0005737|GO:0006415|GO:0016149 ALX04_RS01000 52310784c9a3a56ecba87bc539d25c60 309 Pfam PF03631 Virulence factor BrkB 24 279 1.0E-54 T 28-03-2018 IPR017039 Virulence factor BrkB ALX04_RS01000 52310784c9a3a56ecba87bc539d25c60 309 PIRSF PIRSF035875 1 300 7.9E-77 T 28-03-2018 IPR017039 Virulence factor BrkB ALX04_RS01000 52310784c9a3a56ecba87bc539d25c60 309 TIGRFAM TIGR00765 yihY_not_rbn: YihY family inner membrane protein 16 279 3.3E-31 T 28-03-2018 IPR017039 Virulence factor BrkB ALX04_RS15170 402a50eba80c418160b7816f53e5e256 280 Gene3D G3DSA:1.10.1790.10 47 161 2.7E-16 T 28-03-2018 IPR011608 PRD domain GO:0006355 ALX04_RS15170 402a50eba80c418160b7816f53e5e256 280 Gene3D G3DSA:1.10.1790.10 162 276 7.1E-19 T 28-03-2018 IPR011608 PRD domain GO:0006355 ALX04_RS15170 402a50eba80c418160b7816f53e5e256 280 SUPERFAMILY SSF50151 1 52 2.35E-13 T 28-03-2018 IPR004341 CAT RNA-binding domain GO:0003723 ALX04_RS15170 402a50eba80c418160b7816f53e5e256 280 SMART SM01061 1 59 1.2E-18 T 28-03-2018 IPR004341 CAT RNA-binding domain GO:0003723 ALX04_RS15170 402a50eba80c418160b7816f53e5e256 280 SUPERFAMILY SSF63520 54 162 5.62E-21 T 28-03-2018 IPR011608 PRD domain GO:0006355 ALX04_RS15170 402a50eba80c418160b7816f53e5e256 280 SUPERFAMILY SSF63520 175 272 2.88E-18 T 28-03-2018 IPR011608 PRD domain GO:0006355 ALX04_RS15170 402a50eba80c418160b7816f53e5e256 280 Pfam PF03123 CAT RNA binding domain 1 49 1.3E-13 T 28-03-2018 IPR004341 CAT RNA-binding domain GO:0003723 ALX04_RS15170 402a50eba80c418160b7816f53e5e256 280 Pfam PF00874 PRD domain 73 158 7.0E-13 T 28-03-2018 IPR011608 PRD domain GO:0006355 ALX04_RS15170 402a50eba80c418160b7816f53e5e256 280 Pfam PF00874 PRD domain 180 271 7.6E-14 T 28-03-2018 IPR011608 PRD domain GO:0006355 ALX04_RS15170 402a50eba80c418160b7816f53e5e256 280 Gene3D G3DSA:2.30.24.10 2 46 2.1E-15 T 28-03-2018 IPR004341 CAT RNA-binding domain GO:0003723 ALX04_RS09745 2b1e7efa7d545e2dc7269a151341f7e4 202 Pfam PF00440 Bacterial regulatory proteins, tetR family 17 57 2.9E-8 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 ALX04_RS09745 2b1e7efa7d545e2dc7269a151341f7e4 202 Gene3D G3DSA:1.10.10.60 44 166 2.3E-5 T 28-03-2018 ALX04_RS09745 2b1e7efa7d545e2dc7269a151341f7e4 202 Gene3D G3DSA:1.10.10.60 5 43 6.9E-13 T 28-03-2018 ALX04_RS09745 2b1e7efa7d545e2dc7269a151341f7e4 202 SUPERFAMILY SSF46689 4 65 5.99E-13 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 ALX04_RS12390 312c4ee4f798e9a05920d761f7ae7204 304 Pfam PF00107 Zinc-binding dehydrogenase 149 217 9.5E-9 T 28-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 ALX04_RS12390 312c4ee4f798e9a05920d761f7ae7204 304 Gene3D G3DSA:3.40.50.720 151 283 1.9E-10 T 28-03-2018 ALX04_RS12390 312c4ee4f798e9a05920d761f7ae7204 304 Gene3D G3DSA:3.90.180.10 1 150 8.2E-33 T 28-03-2018 ALX04_RS12390 312c4ee4f798e9a05920d761f7ae7204 304 SUPERFAMILY SSF50129 1 142 3.14E-24 T 28-03-2018 IPR011032 GroES-like ALX04_RS12390 312c4ee4f798e9a05920d761f7ae7204 304 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 28 90 2.2E-8 T 28-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 ALX04_RS12390 312c4ee4f798e9a05920d761f7ae7204 304 SUPERFAMILY SSF51735 110 233 3.71E-22 T 28-03-2018 IPR016040 NAD(P)-binding domain ALX04_RS12390 312c4ee4f798e9a05920d761f7ae7204 304 SMART SM00829 10 302 4.1E-7 T 28-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 ALX04_RS08705 f917ea5e7de7436e01d16d67bbb2b5ab 227 Pfam PF13419 Haloacid dehalogenase-like hydrolase 5 196 4.0E-21 T 28-03-2018 IPR023214 HAD-like domain ALX04_RS08705 f917ea5e7de7436e01d16d67bbb2b5ab 227 SUPERFAMILY SSF56784 2 224 7.01E-42 T 28-03-2018 IPR023214 HAD-like domain ALX04_RS08705 f917ea5e7de7436e01d16d67bbb2b5ab 227 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 139 155 1.1E-6 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 ALX04_RS08705 f917ea5e7de7436e01d16d67bbb2b5ab 227 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 108 121 1.1E-6 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 ALX04_RS08705 f917ea5e7de7436e01d16d67bbb2b5ab 227 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 1 12 1.1E-6 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 ALX04_RS08705 f917ea5e7de7436e01d16d67bbb2b5ab 227 Gene3D G3DSA:1.10.150.240 15 85 2.2E-13 T 28-03-2018 IPR023198 Phosphoglycolate phosphatase, domain 2 ALX04_RS08705 f917ea5e7de7436e01d16d67bbb2b5ab 227 Gene3D G3DSA:3.40.50.1000 86 227 8.1E-30 T 28-03-2018 IPR023214 HAD-like domain ALX04_RS08705 f917ea5e7de7436e01d16d67bbb2b5ab 227 TIGRFAM TIGR02254 YjjG/YfnB: noncanonical pyrimidine nucleotidase, YjjG family 4 223 1.2E-53 T 28-03-2018 IPR011951 HAD-superfamily hydrolase, subfamily IA, YjjG/YfnB GO:0016787 ALX04_RS08705 f917ea5e7de7436e01d16d67bbb2b5ab 227 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 91 189 6.7E-10 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 ALX04_RS07255 4e3464bcd0ba5ae52ddeeb254a542f67 285 Gene3D G3DSA:3.40.50.720 1 171 3.8E-34 T 28-03-2018 ALX04_RS07255 4e3464bcd0ba5ae52ddeeb254a542f67 285 SUPERFAMILY SSF51735 1 162 1.67E-49 T 28-03-2018 IPR016040 NAD(P)-binding domain ALX04_RS07255 4e3464bcd0ba5ae52ddeeb254a542f67 285 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 2 161 1.4E-49 T 28-03-2018 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0004616|GO:0055114 ALX04_RS07255 4e3464bcd0ba5ae52ddeeb254a542f67 285 ProSitePatterns PS00066 Hydroxymethylglutaryl-coenzyme A reductases signature 1. 241 255 - T 28-03-2018 IPR023076 Hydroxymethylglutaryl-CoA reductase, class I/II, conserved site GO:0004420|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 ALX04_RS07255 4e3464bcd0ba5ae52ddeeb254a542f67 285 SUPERFAMILY SSF48179 162 284 9.98E-34 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 ALX04_RS07255 4e3464bcd0ba5ae52ddeeb254a542f67 285 Pfam PF14833 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 164 283 4.4E-31 T 28-03-2018 IPR029154 3-hydroxyisobutyrate dehydrogenase, NAD-binding domain GO:0051287 ALX04_RS07255 4e3464bcd0ba5ae52ddeeb254a542f67 285 PIRSF PIRSF000103 1 285 1.8E-69 T 28-03-2018 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 Reactome: R-HSA-70895 ALX04_RS07255 4e3464bcd0ba5ae52ddeeb254a542f67 285 Gene3D G3DSA:1.10.1040.10 172 285 1.3E-28 T 28-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 ALX04_RS06120 100bd088744e34c575a8a04fcc4952d5 290 Gene3D G3DSA:1.10.260.40 8 194 3.5E-9 T 28-03-2018 ALX04_RS06120 100bd088744e34c575a8a04fcc4952d5 290 SUPERFAMILY SSF47413 8 51 2.98E-6 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 ALX04_RS06120 100bd088744e34c575a8a04fcc4952d5 290 Pfam PF13464 Domain of unknown function (DUF4115) 211 287 1.2E-12 T 28-03-2018 IPR025194 Domain of unknown function DUF4115 ALX04_RS06120 100bd088744e34c575a8a04fcc4952d5 290 Pfam PF13413 Helix-turn-helix domain 14 74 3.6E-22 T 28-03-2018 ALX04_RS11195 bf86dd0756e1b5c8a04956d5e96a5673 325 Pfam PF13377 Periplasmic binding protein-like domain 172 322 4.5E-21 T 28-03-2018 ALX04_RS11195 bf86dd0756e1b5c8a04956d5e96a5673 325 SUPERFAMILY SSF47413 2 61 1.76E-13 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 ALX04_RS11195 bf86dd0756e1b5c8a04956d5e96a5673 325 Gene3D G3DSA:1.10.260.40 1 57 1.9E-18 T 28-03-2018 ALX04_RS11195 bf86dd0756e1b5c8a04956d5e96a5673 325 SMART SM00354 2 73 4.4E-15 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 ALX04_RS11195 bf86dd0756e1b5c8a04956d5e96a5673 325 Gene3D G3DSA:3.40.50.2300 58 168 2.4E-23 T 28-03-2018 ALX04_RS11195 bf86dd0756e1b5c8a04956d5e96a5673 325 Gene3D G3DSA:3.40.50.2300 169 325 5.9E-35 T 28-03-2018 ALX04_RS11195 bf86dd0756e1b5c8a04956d5e96a5673 325 Pfam PF00356 Bacterial regulatory proteins, lacI family 4 50 1.8E-12 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 ALX04_RS11195 bf86dd0756e1b5c8a04956d5e96a5673 325 SUPERFAMILY SSF53822 63 323 2.04E-50 T 28-03-2018 IPR028082 Periplasmic binding protein-like I ALX04_RS01990 018c3592a36b35ebf8919b7092a389c3 483 Gene3D G3DSA:3.40.640.10 148 359 9.6E-42 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 ALX04_RS01990 018c3592a36b35ebf8919b7092a389c3 483 SMART SM00345 22 81 5.0E-15 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 ALX04_RS01990 018c3592a36b35ebf8919b7092a389c3 483 SUPERFAMILY SSF53383 107 477 3.7E-88 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase ALX04_RS01990 018c3592a36b35ebf8919b7092a389c3 483 Pfam PF00155 Aminotransferase class I and II 123 459 4.2E-29 T 28-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 ALX04_RS01990 018c3592a36b35ebf8919b7092a389c3 483 Gene3D G3DSA:3.90.1150.10 360 482 3.7E-22 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 ALX04_RS01990 018c3592a36b35ebf8919b7092a389c3 483 Gene3D G3DSA:1.10.10.10 8 83 1.1E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS01990 018c3592a36b35ebf8919b7092a389c3 483 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 55 71 1.0E-7 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 ALX04_RS01990 018c3592a36b35ebf8919b7092a389c3 483 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 41 55 1.0E-7 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 ALX04_RS01990 018c3592a36b35ebf8919b7092a389c3 483 SUPERFAMILY SSF46785 15 93 2.19E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS01990 018c3592a36b35ebf8919b7092a389c3 483 Pfam PF00392 Bacterial regulatory proteins, gntR family 19 81 1.6E-15 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 ALX04_RS14105 a6b14880929fd4a075086a1f5507f008 291 Gene3D G3DSA:3.30.230.10 1 157 2.5E-29 T 28-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup ALX04_RS14105 a6b14880929fd4a075086a1f5507f008 291 Gene3D G3DSA:3.30.70.890 158 291 1.4E-19 T 28-03-2018 IPR013750 GHMP kinase, C-terminal domain ALX04_RS14105 a6b14880929fd4a075086a1f5507f008 291 Pfam PF00288 GHMP kinases N terminal domain 72 133 5.6E-10 T 28-03-2018 IPR006204 GHMP kinase N-terminal domain GO:0005524 ALX04_RS14105 a6b14880929fd4a075086a1f5507f008 291 Pfam PF08544 GHMP kinases C terminal 194 266 1.9E-6 T 28-03-2018 IPR013750 GHMP kinase, C-terminal domain ALX04_RS14105 a6b14880929fd4a075086a1f5507f008 291 TIGRFAM TIGR00191 thrB: homoserine kinase 2 289 1.3E-69 T 28-03-2018 IPR000870 Homoserine kinase GO:0004413|GO:0005524|GO:0006566 KEGG: 00260+2.7.1.39|MetaCyc: PWY-702 ALX04_RS14105 a6b14880929fd4a075086a1f5507f008 291 ProSitePatterns PS00627 GHMP kinases putative ATP-binding domain. 79 90 - T 28-03-2018 IPR006203 GHMP kinase, ATP-binding, conserved site GO:0005524 ALX04_RS14105 a6b14880929fd4a075086a1f5507f008 291 SUPERFAMILY SSF54211 1 147 9.87E-30 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold ALX04_RS14105 a6b14880929fd4a075086a1f5507f008 291 PRINTS PR00958 Homoserine kinase signature 86 101 6.1E-37 T 28-03-2018 ALX04_RS14105 a6b14880929fd4a075086a1f5507f008 291 PRINTS PR00958 Homoserine kinase signature 120 133 6.1E-37 T 28-03-2018 ALX04_RS14105 a6b14880929fd4a075086a1f5507f008 291 PRINTS PR00958 Homoserine kinase signature 158 175 6.1E-37 T 28-03-2018 ALX04_RS14105 a6b14880929fd4a075086a1f5507f008 291 PRINTS PR00958 Homoserine kinase signature 9 24 6.1E-37 T 28-03-2018 ALX04_RS14105 a6b14880929fd4a075086a1f5507f008 291 PRINTS PR00958 Homoserine kinase signature 238 253 6.1E-37 T 28-03-2018 ALX04_RS14105 a6b14880929fd4a075086a1f5507f008 291 PIRSF PIRSF000676 1 291 2.9E-85 T 28-03-2018 IPR000870 Homoserine kinase GO:0004413|GO:0005524|GO:0006566 KEGG: 00260+2.7.1.39|MetaCyc: PWY-702 ALX04_RS14105 a6b14880929fd4a075086a1f5507f008 291 SUPERFAMILY SSF55060 156 266 1.08E-25 T 28-03-2018 IPR013750 GHMP kinase, C-terminal domain ALX04_RS14105 a6b14880929fd4a075086a1f5507f008 291 Hamap MF_00384 Homoserine kinase [thrB]. 2 288 29.922 T 28-03-2018 IPR000870 Homoserine kinase GO:0004413|GO:0005524|GO:0006566 KEGG: 00260+2.7.1.39|MetaCyc: PWY-702 ALX04_RS04330 78b94cfd26043cdc1105ebdabc752aa8 368 SUPERFAMILY SSF88659 265 366 6.54E-30 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 ALX04_RS04330 78b94cfd26043cdc1105ebdabc752aa8 368 Gene3D G3DSA:1.10.601.10 1 204 4.4E-76 T 28-03-2018 ALX04_RS04330 78b94cfd26043cdc1105ebdabc752aa8 368 Pfam PF03979 Sigma-70 factor, region 1.1 9 81 1.0E-13 T 28-03-2018 IPR007127 RNA polymerase sigma factor 70, region 1.1 GO:0003677|GO:0006355 ALX04_RS04330 78b94cfd26043cdc1105ebdabc752aa8 368 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 328 354 - T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 ALX04_RS04330 78b94cfd26043cdc1105ebdabc752aa8 368 Pfam PF04545 Sigma-70, region 4 303 356 5.0E-20 T 28-03-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 ALX04_RS04330 78b94cfd26043cdc1105ebdabc752aa8 368 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 159 172 - T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 ALX04_RS04330 78b94cfd26043cdc1105ebdabc752aa8 368 Gene3D G3DSA:1.10.10.10 297 368 1.2E-30 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS04330 78b94cfd26043cdc1105ebdabc752aa8 368 Pfam PF04542 Sigma-70 region 2 135 204 1.5E-22 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 ALX04_RS04330 78b94cfd26043cdc1105ebdabc752aa8 368 Pfam PF00140 Sigma-70 factor, region 1.2 97 129 2.2E-17 T 28-03-2018 IPR009042 RNA polymerase sigma-70 region 1.2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 ALX04_RS04330 78b94cfd26043cdc1105ebdabc752aa8 368 SUPERFAMILY SSF88946 96 205 6.41E-55 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 ALX04_RS04330 78b94cfd26043cdc1105ebdabc752aa8 368 SUPERFAMILY SSF88659 208 281 4.11E-23 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 ALX04_RS04330 78b94cfd26043cdc1105ebdabc752aa8 368 PRINTS PR00046 Major sigma-70 factor signature 307 319 2.7E-32 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 ALX04_RS04330 78b94cfd26043cdc1105ebdabc752aa8 368 PRINTS PR00046 Major sigma-70 factor signature 159 172 2.7E-32 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 ALX04_RS04330 78b94cfd26043cdc1105ebdabc752aa8 368 PRINTS PR00046 Major sigma-70 factor signature 343 354 2.7E-32 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 ALX04_RS04330 78b94cfd26043cdc1105ebdabc752aa8 368 PRINTS PR00046 Major sigma-70 factor signature 328 343 2.7E-32 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 ALX04_RS04330 78b94cfd26043cdc1105ebdabc752aa8 368 PRINTS PR00046 Major sigma-70 factor signature 183 191 2.7E-32 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 ALX04_RS04330 78b94cfd26043cdc1105ebdabc752aa8 368 Pfam PF04539 Sigma-70 region 3 214 290 3.3E-32 T 28-03-2018 IPR007624 RNA polymerase sigma-70 region 3 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 ALX04_RS04330 78b94cfd26043cdc1105ebdabc752aa8 368 Hamap MF_00963 RNA polymerase sigma factor RpoD [rpoD]. 9 368 35.026 T 28-03-2018 IPR028630 RNA polymerase sigma factor RpoD GO:0006352|GO:0016987 ALX04_RS04330 78b94cfd26043cdc1105ebdabc752aa8 368 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 131 356 4.3E-39 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 ALX04_RS04330 78b94cfd26043cdc1105ebdabc752aa8 368 Gene3D G3DSA:1.10.10.10 205 255 7.8E-23 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS04330 78b94cfd26043cdc1105ebdabc752aa8 368 TIGRFAM TIGR02393 RpoD_Cterm: RNA polymerase sigma factor RpoD 131 367 1.5E-125 T 28-03-2018 IPR012760 RNA polymerase sigma factor RpoD, C-terminal GO:0003677|GO:0006352|GO:0006355|GO:0016987 ALX04_RS01765 b5bdbf19dbe0d2ed17f2230546d90a45 273 Pfam PF08282 haloacid dehalogenase-like hydrolase 5 268 3.1E-52 T 28-03-2018 IPR023214 HAD-like domain ALX04_RS01765 b5bdbf19dbe0d2ed17f2230546d90a45 273 Gene3D G3DSA:3.40.50.1000 1 273 7.9E-34 T 28-03-2018 IPR023214 HAD-like domain ALX04_RS01765 b5bdbf19dbe0d2ed17f2230546d90a45 273 SUPERFAMILY SSF56784 1 272 8.27E-61 T 28-03-2018 IPR023214 HAD-like domain ALX04_RS01765 b5bdbf19dbe0d2ed17f2230546d90a45 273 TIGRFAM TIGR00099 Cof-subfamily: Cof-like hydrolase 4 268 3.1E-45 T 28-03-2018 IPR000150 Cof family GO:0016787 ALX04_RS01765 b5bdbf19dbe0d2ed17f2230546d90a45 273 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 4 240 6.5E-24 T 28-03-2018 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 ALX04_RS12605 f346464f33e6521f13b2f19609e8a3c2 154 PRINTS PR01243 Nucleoside diphosphate kinase signature 51 70 3.1E-26 T 28-03-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 ALX04_RS12605 f346464f33e6521f13b2f19609e8a3c2 154 PRINTS PR01243 Nucleoside diphosphate kinase signature 7 29 3.1E-26 T 28-03-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 ALX04_RS12605 f346464f33e6521f13b2f19609e8a3c2 154 PRINTS PR01243 Nucleoside diphosphate kinase signature 71 88 3.1E-26 T 28-03-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 ALX04_RS12605 f346464f33e6521f13b2f19609e8a3c2 154 PRINTS PR01243 Nucleoside diphosphate kinase signature 119 138 3.1E-26 T 28-03-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 ALX04_RS12605 f346464f33e6521f13b2f19609e8a3c2 154 SUPERFAMILY SSF54919 5 142 1.57E-45 T 28-03-2018 IPR034907 Nucleoside diphosphate kinase-like domain KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 ALX04_RS12605 f346464f33e6521f13b2f19609e8a3c2 154 Pfam PF00334 Nucleoside diphosphate kinase 5 140 6.4E-47 T 28-03-2018 IPR034907 Nucleoside diphosphate kinase-like domain KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 ALX04_RS12605 f346464f33e6521f13b2f19609e8a3c2 154 SMART SM00562 4 145 4.9E-51 T 28-03-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 ALX04_RS12605 f346464f33e6521f13b2f19609e8a3c2 154 Gene3D G3DSA:3.30.70.141 1 152 1.6E-44 T 28-03-2018 IPR034907 Nucleoside diphosphate kinase-like domain KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 ALX04_RS14340 ad33ade662900bb6e1f1b37db6ab56e0 721 SUPERFAMILY SSF48168 22 168 6.41E-38 T 28-03-2018 IPR008926 Ribonucleotide reductase R1 subunit, N-terminal KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 ALX04_RS14340 ad33ade662900bb6e1f1b37db6ab56e0 721 Gene3D G3DSA:3.20.70.20 72 708 2.8E-156 T 28-03-2018 ALX04_RS14340 ad33ade662900bb6e1f1b37db6ab56e0 721 PRINTS PR01183 Ribonucleotide reductase large chain signature 459 481 6.0E-26 T 28-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 ALX04_RS14340 ad33ade662900bb6e1f1b37db6ab56e0 721 PRINTS PR01183 Ribonucleotide reductase large chain signature 569 596 6.0E-26 T 28-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 ALX04_RS14340 ad33ade662900bb6e1f1b37db6ab56e0 721 PRINTS PR01183 Ribonucleotide reductase large chain signature 376 387 6.0E-26 T 28-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 ALX04_RS14340 ad33ade662900bb6e1f1b37db6ab56e0 721 PRINTS PR01183 Ribonucleotide reductase large chain signature 245 264 6.0E-26 T 28-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 ALX04_RS14340 ad33ade662900bb6e1f1b37db6ab56e0 721 PRINTS PR01183 Ribonucleotide reductase large chain signature 487 510 6.0E-26 T 28-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 ALX04_RS14340 ad33ade662900bb6e1f1b37db6ab56e0 721 TIGRFAM TIGR04170 RNR_1b_NrdE: ribonucleoside-diphosphate reductase, class 1b, alpha subunit 10 721 0.0 T 28-03-2018 IPR026459 Ribonucleotide reductase, class 1b, subunit NrdE KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227 ALX04_RS14340 ad33ade662900bb6e1f1b37db6ab56e0 721 Pfam PF08343 Ribonucleotide reductase N-terminal 11 91 6.6E-26 T 28-03-2018 IPR013554 Ribonucleotide reductase N-terminal KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227 ALX04_RS14340 ad33ade662900bb6e1f1b37db6ab56e0 721 ProSitePatterns PS00089 Ribonucleotide reductase large subunit signature. 558 580 - T 28-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 ALX04_RS14340 ad33ade662900bb6e1f1b37db6ab56e0 721 TIGRFAM TIGR02506 NrdE_NrdA: ribonucleoside-diphosphate reductase, alpha subunit 96 703 1.1E-149 T 28-03-2018 IPR013346 Ribonucleotide reductase, class I , alpha subunit GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 ALX04_RS14340 ad33ade662900bb6e1f1b37db6ab56e0 721 Pfam PF02867 Ribonucleotide reductase, barrel domain 171 700 2.4E-143 T 28-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 ALX04_RS14340 ad33ade662900bb6e1f1b37db6ab56e0 721 Pfam PF00317 Ribonucleotide reductase, all-alpha domain 94 165 2.5E-9 T 28-03-2018 IPR013509 Ribonucleotide reductase large subunit, N-terminal GO:0004748|GO:0005524|GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 ALX04_RS14340 ad33ade662900bb6e1f1b37db6ab56e0 721 SUPERFAMILY SSF51998 169 703 3.36E-176 T 28-03-2018 ALX04_RS05670 ce13b03ab31456e0fadaff8272b2aee4 247 SUPERFAMILY SSF56281 1 246 7.89E-45 T 28-03-2018 IPR001279 Metallo-beta-lactamase ALX04_RS05670 ce13b03ab31456e0fadaff8272b2aee4 247 Pfam PF12706 Beta-lactamase superfamily domain 31 211 1.3E-16 T 28-03-2018 IPR001279 Metallo-beta-lactamase ALX04_RS05670 ce13b03ab31456e0fadaff8272b2aee4 247 SMART SM00849 18 211 7.2E-7 T 28-03-2018 IPR001279 Metallo-beta-lactamase ALX04_RS05670 ce13b03ab31456e0fadaff8272b2aee4 247 Gene3D G3DSA:3.60.15.10 1 246 1.6E-39 T 28-03-2018 IPR001279 Metallo-beta-lactamase ALX04_RS00590 14957bc644184ca5cb158c155240b958 362 Gene3D G3DSA:1.10.1530.10 2 79 2.8E-23 T 28-03-2018 ALX04_RS00590 14957bc644184ca5cb158c155240b958 362 Pfam PF02615 Malate/L-lactate dehydrogenase 3 346 4.2E-103 T 28-03-2018 IPR003767 Malate/L-lactate dehydrogenase-like GO:0008152|GO:0016491|GO:0055114 ALX04_RS00590 14957bc644184ca5cb158c155240b958 362 Gene3D G3DSA:3.30.1370.60 80 318 5.7E-75 T 28-03-2018 ALX04_RS00590 14957bc644184ca5cb158c155240b958 362 SUPERFAMILY SSF89733 1 357 1.19E-95 T 28-03-2018 IPR003767 Malate/L-lactate dehydrogenase-like GO:0008152|GO:0016491|GO:0055114 ALX04_RS05320 7882b73f85985808cb99168e8a53857d 97 Hamap MF_01041 UPF0223 protein . 8 95 24.632 T 28-03-2018 IPR007920 Protein of unknown function UPF0223 ALX04_RS05320 7882b73f85985808cb99168e8a53857d 97 SUPERFAMILY SSF158504 11 93 1.18E-29 T 28-03-2018 IPR023324 BH2638-like domain ALX04_RS05320 7882b73f85985808cb99168e8a53857d 97 PIRSF PIRSF037260 6 97 7.5E-40 T 28-03-2018 IPR007920 Protein of unknown function UPF0223 ALX04_RS05320 7882b73f85985808cb99168e8a53857d 97 Gene3D G3DSA:1.10.220.80 19 95 3.6E-29 T 28-03-2018 IPR023324 BH2638-like domain ALX04_RS05320 7882b73f85985808cb99168e8a53857d 97 Pfam PF05256 Uncharacterised protein family (UPF0223) 9 93 1.5E-34 T 28-03-2018 IPR007920 Protein of unknown function UPF0223 ALX04_RS05320 7882b73f85985808cb99168e8a53857d 97 ProDom PD062738 UPF0223 FAMILY UNCHARACTERISED CYTOSOLIC SUPERFAMILY YKTA LMO1058/LIN1050 INOSITOL MW0980 M6_SPY0948 9 94 4.0E-44 T 28-03-2018 IPR007920 Protein of unknown function UPF0223 ALX04_RS11305 fd27896369a7643b48b10d4d8e470d07 242 SUPERFAMILY SSF53639 1 222 1.96E-69 T 28-03-2018 IPR001303 Class II aldolase/adducin N-terminal ALX04_RS11305 fd27896369a7643b48b10d4d8e470d07 242 Gene3D G3DSA:3.40.225.10 1 230 3.5E-62 T 28-03-2018 IPR001303 Class II aldolase/adducin N-terminal ALX04_RS11305 fd27896369a7643b48b10d4d8e470d07 242 SMART SM01007 7 197 8.4E-66 T 28-03-2018 IPR001303 Class II aldolase/adducin N-terminal ALX04_RS11305 fd27896369a7643b48b10d4d8e470d07 242 Pfam PF00596 Class II Aldolase and Adducin N-terminal domain 7 194 5.5E-46 T 28-03-2018 IPR001303 Class II aldolase/adducin N-terminal ALX04_RS12920 928e6ed514b10c6e118ea25bb93c7ba6 789 SMART SM00488 181 424 6.0E-4 T 28-03-2018 IPR006554 Helicase-like, DEXD box c2 type GO:0004003|GO:0016818 ALX04_RS12920 928e6ed514b10c6e118ea25bb93c7ba6 789 Pfam PF12705 PD-(D/E)XK nuclease superfamily 28 161 7.5E-6 T 28-03-2018 ALX04_RS12920 928e6ed514b10c6e118ea25bb93c7ba6 789 Gene3D G3DSA:3.40.50.300 168 565 4.6E-20 T 28-03-2018 ALX04_RS12920 928e6ed514b10c6e118ea25bb93c7ba6 789 SUPERFAMILY SSF52540 151 285 5.83E-17 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase ALX04_RS12920 928e6ed514b10c6e118ea25bb93c7ba6 789 SUPERFAMILY SSF52540 343 394 5.83E-17 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase ALX04_RS12920 928e6ed514b10c6e118ea25bb93c7ba6 789 SUPERFAMILY SSF52540 343 398 6.1E-16 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase ALX04_RS12920 928e6ed514b10c6e118ea25bb93c7ba6 789 SUPERFAMILY SSF52540 208 258 6.1E-16 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase ALX04_RS12920 928e6ed514b10c6e118ea25bb93c7ba6 789 SUPERFAMILY SSF52540 529 543 6.1E-16 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase ALX04_RS12920 928e6ed514b10c6e118ea25bb93c7ba6 789 SUPERFAMILY SSF52540 571 745 6.1E-16 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase ALX04_RS12920 928e6ed514b10c6e118ea25bb93c7ba6 789 SMART SM00491 614 751 7.1E-7 T 28-03-2018 IPR006555 ATP-dependent helicase, C-terminal GO:0003676|GO:0005524|GO:0006139|GO:0008026|GO:0016818 ALX04_RS12920 928e6ed514b10c6e118ea25bb93c7ba6 789 Pfam PF06733 DEAD_2 319 396 1.1E-6 T 28-03-2018 IPR010614 DEAD2 GO:0003677|GO:0004003|GO:0005524 ALX04_RS12920 928e6ed514b10c6e118ea25bb93c7ba6 789 Pfam PF13307 Helicase C-terminal domain 598 763 3.1E-36 T 28-03-2018 IPR006555 ATP-dependent helicase, C-terminal GO:0003676|GO:0005524|GO:0006139|GO:0008026|GO:0016818 ALX04_RS12920 928e6ed514b10c6e118ea25bb93c7ba6 789 Gene3D G3DSA:3.40.50.300 567 772 4.4E-9 T 28-03-2018 ALX04_RS09990 6d5b01b0a2a3d1f1159c625b939a0169 333 Pfam PF00356 Bacterial regulatory proteins, lacI family 3 48 3.1E-15 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 ALX04_RS09990 6d5b01b0a2a3d1f1159c625b939a0169 333 SMART SM00354 1 71 7.5E-28 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 ALX04_RS09990 6d5b01b0a2a3d1f1159c625b939a0169 333 ProSitePatterns PS00356 LacI-type HTH domain signature. 4 22 - T 28-03-2018 ALX04_RS09990 6d5b01b0a2a3d1f1159c625b939a0169 333 SUPERFAMILY SSF47413 1 59 4.13E-15 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 ALX04_RS09990 6d5b01b0a2a3d1f1159c625b939a0169 333 Pfam PF13377 Periplasmic binding protein-like domain 169 332 1.4E-35 T 28-03-2018 ALX04_RS09990 6d5b01b0a2a3d1f1159c625b939a0169 333 SUPERFAMILY SSF53822 59 313 2.17E-63 T 28-03-2018 IPR028082 Periplasmic binding protein-like I ALX04_RS09990 6d5b01b0a2a3d1f1159c625b939a0169 333 Gene3D G3DSA:3.40.50.2300 55 173 6.0E-29 T 28-03-2018 ALX04_RS09990 6d5b01b0a2a3d1f1159c625b939a0169 333 Gene3D G3DSA:3.40.50.2300 174 312 5.6E-37 T 28-03-2018 ALX04_RS09990 6d5b01b0a2a3d1f1159c625b939a0169 333 Gene3D G3DSA:1.10.260.40 2 54 5.8E-21 T 28-03-2018 ALX04_RS03180 854cf2304b69a2014e120cc00cf01903 152 PRINTS PR01438 Universal stress protein signature 2 20 9.0E-16 T 28-03-2018 IPR006015 Universal stress protein A ALX04_RS03180 854cf2304b69a2014e120cc00cf01903 152 PRINTS PR01438 Universal stress protein signature 106 118 9.0E-16 T 28-03-2018 IPR006015 Universal stress protein A ALX04_RS03180 854cf2304b69a2014e120cc00cf01903 152 PRINTS PR01438 Universal stress protein signature 124 146 9.0E-16 T 28-03-2018 IPR006015 Universal stress protein A ALX04_RS03180 854cf2304b69a2014e120cc00cf01903 152 SUPERFAMILY SSF52402 2 146 2.85E-28 T 28-03-2018 ALX04_RS03180 854cf2304b69a2014e120cc00cf01903 152 Pfam PF00582 Universal stress protein family 1 145 1.7E-28 T 28-03-2018 IPR006016 UspA GO:0006950 ALX04_RS03180 854cf2304b69a2014e120cc00cf01903 152 Gene3D G3DSA:3.40.50.620 1 145 6.9E-28 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold ALX04_RS04270 77dd2660d27609e8766ca8974cb5fc5f 155 Gene3D G3DSA:1.10.10.10 14 151 6.3E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS04270 77dd2660d27609e8766ca8974cb5fc5f 155 PRINTS PR00598 Bacterial regulatory protein MarR family signature 60 76 1.3E-5 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 ALX04_RS04270 77dd2660d27609e8766ca8974cb5fc5f 155 PRINTS PR00598 Bacterial regulatory protein MarR family signature 96 112 1.3E-5 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 ALX04_RS04270 77dd2660d27609e8766ca8974cb5fc5f 155 PRINTS PR00598 Bacterial regulatory protein MarR family signature 77 92 1.3E-5 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 ALX04_RS04270 77dd2660d27609e8766ca8974cb5fc5f 155 Pfam PF01047 MarR family 45 100 7.6E-14 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 ALX04_RS04270 77dd2660d27609e8766ca8974cb5fc5f 155 SUPERFAMILY SSF46785 18 151 2.06E-24 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS04270 77dd2660d27609e8766ca8974cb5fc5f 155 SMART SM00347 36 136 5.6E-14 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 ALX04_RS05990 c6ac8e82e44942cea834189a3d25fa4b 787 Hamap MF_00092 Endonuclease MutS2 [mutS2]. 2 786 20.818 T 28-03-2018 IPR005747 Endonuclease MutS2 GO:0004519|GO:0016887|GO:0030983|GO:0045910 ALX04_RS05990 c6ac8e82e44942cea834189a3d25fa4b 787 SMART SM00463 709 787 1.9E-19 T 28-03-2018 IPR002625 Smr domain ALX04_RS05990 c6ac8e82e44942cea834189a3d25fa4b 787 SMART SM00533 9 316 3.0E-16 T 28-03-2018 IPR007696 DNA mismatch repair protein MutS, core GO:0005524|GO:0006298|GO:0030983 ALX04_RS05990 c6ac8e82e44942cea834189a3d25fa4b 787 Gene3D G3DSA:3.40.50.300 293 558 5.3E-38 T 28-03-2018 ALX04_RS05990 c6ac8e82e44942cea834189a3d25fa4b 787 Pfam PF01713 Smr domain 712 787 2.7E-20 T 28-03-2018 IPR002625 Smr domain ALX04_RS05990 c6ac8e82e44942cea834189a3d25fa4b 787 Pfam PF00488 MutS domain V 332 512 2.1E-35 T 28-03-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 ALX04_RS05990 c6ac8e82e44942cea834189a3d25fa4b 787 SUPERFAMILY SSF160443 711 786 3.53E-9 T 28-03-2018 IPR002625 Smr domain ALX04_RS05990 c6ac8e82e44942cea834189a3d25fa4b 787 SUPERFAMILY SSF48334 6 289 1.44E-32 T 28-03-2018 IPR007696 DNA mismatch repair protein MutS, core GO:0005524|GO:0006298|GO:0030983 ALX04_RS05990 c6ac8e82e44942cea834189a3d25fa4b 787 Gene3D G3DSA:1.10.1420.10 16 291 1.3E-4 T 28-03-2018 ALX04_RS05990 c6ac8e82e44942cea834189a3d25fa4b 787 TIGRFAM TIGR01069 mutS2: MutS2 family protein 3 785 2.9E-230 T 28-03-2018 IPR005747 Endonuclease MutS2 GO:0004519|GO:0016887|GO:0030983|GO:0045910 ALX04_RS05990 c6ac8e82e44942cea834189a3d25fa4b 787 ProSitePatterns PS00486 DNA mismatch repair proteins mutS family signature. 411 427 - T 28-03-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 ALX04_RS05990 c6ac8e82e44942cea834189a3d25fa4b 787 PIRSF PIRSF005814 1 787 6.0E-254 T 28-03-2018 IPR005747 Endonuclease MutS2 GO:0004519|GO:0016887|GO:0030983|GO:0045910 ALX04_RS05990 c6ac8e82e44942cea834189a3d25fa4b 787 SUPERFAMILY SSF52540 294 515 3.86E-45 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase ALX04_RS05990 c6ac8e82e44942cea834189a3d25fa4b 787 SMART SM00534 329 514 5.4E-72 T 28-03-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 ALX04_RS08645 f6eee2a62c34862f0fef1755672b4c19 156 Pfam PF12682 Flavodoxin 7 126 9.7E-24 T 28-03-2018 IPR008254 Flavodoxin/nitric oxide synthase GO:0010181 ALX04_RS08645 f6eee2a62c34862f0fef1755672b4c19 156 SUPERFAMILY SSF52218 6 117 5.06E-16 T 28-03-2018 IPR029039 Flavoprotein-like domain ALX04_RS08645 f6eee2a62c34862f0fef1755672b4c19 156 Gene3D G3DSA:3.40.50.360 2 153 1.8E-28 T 28-03-2018 IPR029039 Flavoprotein-like domain ALX04_RS07265 adad8a1c506511e680e39dae3b049990 184 Pfam PF12464 Maltose acetyltransferase 6 57 6.3E-11 T 28-03-2018 IPR024688 Maltose/galactoside acetyltransferase GO:0016407 ALX04_RS07265 adad8a1c506511e680e39dae3b049990 184 Pfam PF14602 Hexapeptide repeat of succinyl-transferase 93 106 0.0072 T 28-03-2018 IPR001451 Hexapeptide repeat ALX04_RS07265 adad8a1c506511e680e39dae3b049990 184 SMART SM01266 4 58 4.7E-13 T 28-03-2018 IPR024688 Maltose/galactoside acetyltransferase GO:0016407 ALX04_RS07265 adad8a1c506511e680e39dae3b049990 184 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 130 164 3.8E-10 T 28-03-2018 IPR001451 Hexapeptide repeat ALX04_RS07265 adad8a1c506511e680e39dae3b049990 184 SUPERFAMILY SSF51161 2 182 2.63E-48 T 28-03-2018 IPR011004 Trimeric LpxA-like ALX04_RS07265 adad8a1c506511e680e39dae3b049990 184 Gene3D G3DSA:2.160.10.10 1 184 3.8E-48 T 28-03-2018 ALX04_RS01875 ac24e92875c8f75fe8bf26c82fd9cdc9 391 Gene3D G3DSA:3.40.50.620 179 379 4.9E-87 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold ALX04_RS01875 ac24e92875c8f75fe8bf26c82fd9cdc9 391 TIGRFAM TIGR00339 sopT: sulfate adenylyltransferase 10 379 2.1E-132 T 28-03-2018 IPR002650 Sulphate adenylyltransferase GO:0000103|GO:0004781 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932|Reactome: R-HSA-174362|Reactome: R-HSA-2408550 ALX04_RS01875 ac24e92875c8f75fe8bf26c82fd9cdc9 391 Gene3D G3DSA:3.10.400.10 6 178 4.5E-60 T 28-03-2018 ALX04_RS01875 ac24e92875c8f75fe8bf26c82fd9cdc9 391 SUPERFAMILY SSF52374 168 379 4.07E-83 T 28-03-2018 ALX04_RS01875 ac24e92875c8f75fe8bf26c82fd9cdc9 391 SUPERFAMILY SSF88697 7 167 6.56E-49 T 28-03-2018 IPR015947 PUA-like domain ALX04_RS01875 ac24e92875c8f75fe8bf26c82fd9cdc9 391 Hamap MF_00066 Sulfate adenylyltransferase [sat]. 27 383 48.492 T 28-03-2018 IPR020792 Sulphate adenylyltransferase, prokaryotic-type GO:0000103|GO:0004781 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932 ALX04_RS01875 ac24e92875c8f75fe8bf26c82fd9cdc9 391 Pfam PF14306 PUA-like domain 8 161 4.5E-51 T 28-03-2018 IPR025980 ATP-sulfurylase PUA-like domain KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932|Reactome: R-HSA-174362|Reactome: R-HSA-2408550 ALX04_RS01875 ac24e92875c8f75fe8bf26c82fd9cdc9 391 Pfam PF01747 ATP-sulfurylase 170 378 3.0E-90 T 28-03-2018 IPR024951 Sulphate adenylyltransferase catalytic domain GO:0004781 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932|Reactome: R-HSA-174362|Reactome: R-HSA-2408550 ALX04_RS12120 e1ab8aa0f1d44d92cf37c4709eee6c91 200 SUPERFAMILY SSF52218 3 168 1.77E-31 T 28-03-2018 IPR029039 Flavoprotein-like domain ALX04_RS12120 e1ab8aa0f1d44d92cf37c4709eee6c91 200 Pfam PF03358 NADPH-dependent FMN reductase 3 148 4.6E-25 T 28-03-2018 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 ALX04_RS12120 e1ab8aa0f1d44d92cf37c4709eee6c91 200 Gene3D G3DSA:3.40.50.360 1 184 4.5E-26 T 28-03-2018 IPR029039 Flavoprotein-like domain ALX04_RS06795 0b9074ef20cf2d2bfe4ca416a46481df 76 SUPERFAMILY SSF47413 3 52 1.18E-10 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 ALX04_RS06795 0b9074ef20cf2d2bfe4ca416a46481df 76 Pfam PF01381 Helix-turn-helix 5 51 5.6E-11 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 ALX04_RS06795 0b9074ef20cf2d2bfe4ca416a46481df 76 Gene3D G3DSA:1.10.260.40 1 76 4.6E-11 T 28-03-2018 ALX04_RS06795 0b9074ef20cf2d2bfe4ca416a46481df 76 SMART SM00530 4 58 1.5E-6 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 ALX04_RS08730 fc8985baa94d9f69d3bce355c5d7fe61 342 Pfam PF00248 Aldo/keto reductase family 26 314 1.5E-64 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain ALX04_RS08730 fc8985baa94d9f69d3bce355c5d7fe61 342 PRINTS PR00069 Aldo-keto reductase signature 146 163 5.5E-8 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 ALX04_RS08730 fc8985baa94d9f69d3bce355c5d7fe61 342 PRINTS PR00069 Aldo-keto reductase signature 50 74 5.5E-8 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 ALX04_RS08730 fc8985baa94d9f69d3bce355c5d7fe61 342 PRINTS PR00069 Aldo-keto reductase signature 115 133 5.5E-8 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 ALX04_RS08730 fc8985baa94d9f69d3bce355c5d7fe61 342 Gene3D G3DSA:3.20.20.100 1 342 8.9E-87 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain ALX04_RS08730 fc8985baa94d9f69d3bce355c5d7fe61 342 SUPERFAMILY SSF51430 1 320 3.14E-90 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain ALX04_RS11030 d1e2a5ab7fe16d74baf59cba6eebec68 738 Gene3D G3DSA:2.60.40.1180 641 737 1.5E-25 T 28-03-2018 ALX04_RS11030 d1e2a5ab7fe16d74baf59cba6eebec68 738 Gene3D G3DSA:2.70.98.60 8 317 3.5E-101 T 28-03-2018 ALX04_RS11030 d1e2a5ab7fe16d74baf59cba6eebec68 738 Pfam PF02065 Melibiase 297 643 1.5E-173 T 28-03-2018 IPR002252 Glycoside hydrolase family 36 GO:0004557|GO:0005975 ALX04_RS11030 d1e2a5ab7fe16d74baf59cba6eebec68 738 Gene3D G3DSA:3.20.20.70 318 640 6.9E-57 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 ALX04_RS11030 d1e2a5ab7fe16d74baf59cba6eebec68 738 ProSitePatterns PS00512 Alpha-galactosidase signature. 367 382 - T 28-03-2018 IPR000111 Glycoside hydrolase family 27/36, conserved site GO:0004553|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 ALX04_RS11030 d1e2a5ab7fe16d74baf59cba6eebec68 738 SUPERFAMILY SSF51445 333 674 8.29E-107 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily ALX04_RS11030 d1e2a5ab7fe16d74baf59cba6eebec68 738 Pfam PF16874 Glycosyl hydrolase family 36 C-terminal domain 657 734 8.5E-19 T 28-03-2018 IPR031705 Glycosyl hydrolase family 36, C-terminal KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 ALX04_RS11030 d1e2a5ab7fe16d74baf59cba6eebec68 738 Pfam PF16875 Glycosyl hydrolase family 36 N-terminal domain 37 293 2.7E-88 T 28-03-2018 IPR031704 Glycosyl hydrolase family 36, N-terminal KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 ALX04_RS11030 d1e2a5ab7fe16d74baf59cba6eebec68 738 PRINTS PR00743 Glycosyl hydrolase family 36 signature 338 352 8.0E-63 T 28-03-2018 IPR002252 Glycoside hydrolase family 36 GO:0004557|GO:0005975 ALX04_RS11030 d1e2a5ab7fe16d74baf59cba6eebec68 738 PRINTS PR00743 Glycosyl hydrolase family 36 signature 366 381 8.0E-63 T 28-03-2018 IPR002252 Glycoside hydrolase family 36 GO:0004557|GO:0005975 ALX04_RS11030 d1e2a5ab7fe16d74baf59cba6eebec68 738 PRINTS PR00743 Glycosyl hydrolase family 36 signature 249 264 8.0E-63 T 28-03-2018 IPR002252 Glycoside hydrolase family 36 GO:0004557|GO:0005975 ALX04_RS11030 d1e2a5ab7fe16d74baf59cba6eebec68 738 PRINTS PR00743 Glycosyl hydrolase family 36 signature 553 569 8.0E-63 T 28-03-2018 IPR002252 Glycoside hydrolase family 36 GO:0004557|GO:0005975 ALX04_RS11030 d1e2a5ab7fe16d74baf59cba6eebec68 738 PRINTS PR00743 Glycosyl hydrolase family 36 signature 416 438 8.0E-63 T 28-03-2018 IPR002252 Glycoside hydrolase family 36 GO:0004557|GO:0005975 ALX04_RS11030 d1e2a5ab7fe16d74baf59cba6eebec68 738 PRINTS PR00743 Glycosyl hydrolase family 36 signature 474 489 8.0E-63 T 28-03-2018 IPR002252 Glycoside hydrolase family 36 GO:0004557|GO:0005975 ALX04_RS11030 d1e2a5ab7fe16d74baf59cba6eebec68 738 PRINTS PR00743 Glycosyl hydrolase family 36 signature 300 320 8.0E-63 T 28-03-2018 IPR002252 Glycoside hydrolase family 36 GO:0004557|GO:0005975 ALX04_RS11030 d1e2a5ab7fe16d74baf59cba6eebec68 738 PRINTS PR00743 Glycosyl hydrolase family 36 signature 528 544 8.0E-63 T 28-03-2018 IPR002252 Glycoside hydrolase family 36 GO:0004557|GO:0005975 ALX04_RS11030 d1e2a5ab7fe16d74baf59cba6eebec68 738 PIRSF PIRSF005536 8 737 0.0 T 28-03-2018 IPR002252 Glycoside hydrolase family 36 GO:0004557|GO:0005975 ALX04_RS13100 cea37c81b637a266fda9a83047338d68 438 Gene3D G3DSA:1.10.3430.10 1 385 7.1E-123 T 28-03-2018 ALX04_RS13100 cea37c81b637a266fda9a83047338d68 438 SUPERFAMILY SSF111352 2 385 3.27E-117 T 28-03-2018 IPR024041 Ammonium transporter AmtB-like domain GO:0008519|GO:0015696|GO:0016020 ALX04_RS13100 cea37c81b637a266fda9a83047338d68 438 ProSitePatterns PS01219 Ammonium transporters signature. 157 182 - T 28-03-2018 IPR018047 Ammonium transporter, conserved site GO:0008519|GO:0016020|GO:0072488 ALX04_RS13100 cea37c81b637a266fda9a83047338d68 438 TIGRFAM TIGR00836 amt: ammonium transporter 6 403 9.7E-125 T 28-03-2018 IPR001905 Ammonium transporter GO:0008519|GO:0016020|GO:0072488 ALX04_RS13100 cea37c81b637a266fda9a83047338d68 438 Pfam PF00909 Ammonium Transporter Family 8 403 3.4E-116 T 28-03-2018 IPR024041 Ammonium transporter AmtB-like domain GO:0008519|GO:0015696|GO:0016020 ALX04_RS15390 fdbae2cb86664ac6a0d60973075a86e4 305 Gene3D G3DSA:1.10.150.130 1 113 2.4E-9 T 28-03-2018 IPR023109 Integrase/recombinase, N-terminal ALX04_RS15390 fdbae2cb86664ac6a0d60973075a86e4 305 SUPERFAMILY SSF56349 7 292 1.59E-48 T 28-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 ALX04_RS15390 fdbae2cb86664ac6a0d60973075a86e4 305 Pfam PF00589 Phage integrase family 112 285 2.5E-24 T 28-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 ALX04_RS15390 fdbae2cb86664ac6a0d60973075a86e4 305 Gene3D G3DSA:1.10.443.10 114 303 4.0E-31 T 28-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 ALX04_RS07925 a8e8cdae55e61a32ad292fbe1d060ed2 243 ProSitePatterns PS01057 SAICAR synthetase signature 1. 90 104 - T 28-03-2018 IPR018236 SAICAR synthetase, conserved site GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 ALX04_RS07925 a8e8cdae55e61a32ad292fbe1d060ed2 243 Hamap MF_00137 Phosphoribosylaminoimidazole-succinocarboxamide synthase [purC]. 8 239 28.016 T 28-03-2018 IPR028923 SAICAR synthetase/ADE2, N-terminal KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 ALX04_RS07925 a8e8cdae55e61a32ad292fbe1d060ed2 243 Gene3D G3DSA:3.30.200.20 1 95 8.9E-25 T 28-03-2018 ALX04_RS07925 a8e8cdae55e61a32ad292fbe1d060ed2 243 SUPERFAMILY SSF56104 5 237 3.2E-72 T 28-03-2018 ALX04_RS07925 a8e8cdae55e61a32ad292fbe1d060ed2 243 ProSitePatterns PS01058 SAICAR synthetase signature 2. 177 185 - T 28-03-2018 IPR018236 SAICAR synthetase, conserved site GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 ALX04_RS07925 a8e8cdae55e61a32ad292fbe1d060ed2 243 Gene3D G3DSA:3.30.470.20 96 225 1.2E-43 T 28-03-2018 ALX04_RS07925 a8e8cdae55e61a32ad292fbe1d060ed2 243 TIGRFAM TIGR00081 purC: phosphoribosylaminoimidazolesuccinocarboxamide synthase 7 238 2.4E-60 T 28-03-2018 IPR001636 Phosphoribosylaminoimidazole-succinocarboxamide synthase GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234 ALX04_RS07925 a8e8cdae55e61a32ad292fbe1d060ed2 243 Pfam PF01259 SAICAR synthetase 11 236 5.3E-59 T 28-03-2018 IPR028923 SAICAR synthetase/ADE2, N-terminal KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 ALX04_RS00170 f6e8a38bcd6f06548304f550caaa11fb 309 Gene3D G3DSA:1.10.10.10 58 135 3.2E-6 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS00170 f6e8a38bcd6f06548304f550caaa11fb 309 Pfam PF13936 Helix-turn-helix domain 4 42 8.3E-9 T 28-03-2018 IPR025246 Transposase IS30-like HTH domain ALX04_RS00170 f6e8a38bcd6f06548304f550caaa11fb 309 Gene3D G3DSA:1.10.10.60 2 48 1.1E-8 T 28-03-2018 ALX04_RS00170 f6e8a38bcd6f06548304f550caaa11fb 309 Pfam PF00665 Integrase core domain 160 259 1.8E-16 T 28-03-2018 IPR001584 Integrase, catalytic core GO:0015074 ALX04_RS00170 f6e8a38bcd6f06548304f550caaa11fb 309 SUPERFAMILY SSF53098 158 300 3.41E-28 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 ALX04_RS00170 f6e8a38bcd6f06548304f550caaa11fb 309 Gene3D G3DSA:3.30.420.10 156 309 5.9E-26 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 ALX04_RS02975 be90d87136f28082f51a244c420eeaa3 179 Gene3D G3DSA:3.40.50.850 1 178 1.1E-32 T 28-03-2018 ALX04_RS02975 be90d87136f28082f51a244c420eeaa3 179 SUPERFAMILY SSF52499 4 161 9.68E-42 T 28-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 ALX04_RS02975 be90d87136f28082f51a244c420eeaa3 179 Pfam PF00857 Isochorismatase family 4 134 8.0E-27 T 28-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 ALX04_RS03335 0e79651dad6de785565ff7ce295d0f5e 401 Gene3D G3DSA:3.90.1150.10 274 396 5.5E-24 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 ALX04_RS03335 0e79651dad6de785565ff7ce295d0f5e 401 Pfam PF00155 Aminotransferase class I and II 33 387 4.6E-66 T 28-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 ALX04_RS03335 0e79651dad6de785565ff7ce295d0f5e 401 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 235 248 - T 28-03-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 ALX04_RS03335 0e79651dad6de785565ff7ce295d0f5e 401 Gene3D G3DSA:3.40.640.10 46 273 1.4E-47 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 ALX04_RS03335 0e79651dad6de785565ff7ce295d0f5e 401 PRINTS PR00753 1-aminocyclopropane-1-carboxylate synthase signature 162 186 4.9E-14 T 28-03-2018 ALX04_RS03335 0e79651dad6de785565ff7ce295d0f5e 401 PRINTS PR00753 1-aminocyclopropane-1-carboxylate synthase signature 198 221 4.9E-14 T 28-03-2018 ALX04_RS03335 0e79651dad6de785565ff7ce295d0f5e 401 PRINTS PR00753 1-aminocyclopropane-1-carboxylate synthase signature 117 138 4.9E-14 T 28-03-2018 ALX04_RS03335 0e79651dad6de785565ff7ce295d0f5e 401 PRINTS PR00753 1-aminocyclopropane-1-carboxylate synthase signature 229 253 4.9E-14 T 28-03-2018 ALX04_RS03335 0e79651dad6de785565ff7ce295d0f5e 401 PRINTS PR00753 1-aminocyclopropane-1-carboxylate synthase signature 95 115 4.9E-14 T 28-03-2018 ALX04_RS03335 0e79651dad6de785565ff7ce295d0f5e 401 SUPERFAMILY SSF53383 3 393 1.75E-106 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase ALX04_RS06095 336cd9ee750a6bff0ac5b5f050526f51 268 Pfam PF13277 YmdB-like protein 4 257 2.7E-105 T 28-03-2018 IPR005235 Metallophosphoesterase, YmdB-like ALX04_RS06095 336cd9ee750a6bff0ac5b5f050526f51 268 Gene3D G3DSA:3.60.21.10 1 267 1.3E-49 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like ALX04_RS06095 336cd9ee750a6bff0ac5b5f050526f51 268 SUPERFAMILY SSF56300 1 259 3.8E-81 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like ALX04_RS06095 336cd9ee750a6bff0ac5b5f050526f51 268 TIGRFAM TIGR00282 TIGR00282: metallophosphoesterase, MG_246/BB_0505 family 1 266 5.7E-100 T 28-03-2018 IPR005235 Metallophosphoesterase, YmdB-like ALX04_RS06095 336cd9ee750a6bff0ac5b5f050526f51 268 PIRSF PIRSF004789 1 266 3.4E-101 T 28-03-2018 IPR005235 Metallophosphoesterase, YmdB-like ALX04_RS08310 4c71a194307215cc7d07f24ed16fb79e 256 PIRSF PIRSF032442 1 254 6.3E-86 T 28-03-2018 IPR016997 Uncharacterised conserved protein UCP032442 ALX04_RS08310 4c71a194307215cc7d07f24ed16fb79e 256 Gene3D G3DSA:3.90.70.10 76 255 1.5E-20 T 28-03-2018 ALX04_RS08310 4c71a194307215cc7d07f24ed16fb79e 256 Pfam PF13529 Peptidase_C39 like family 64 226 9.8E-39 T 28-03-2018 ALX04_RS03040 7741dc1f2e9b1eb49b0b3cf130e7650d 242 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 79 90 2.2E-43 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR ALX04_RS03040 7741dc1f2e9b1eb49b0b3cf130e7650d 242 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 173 190 2.2E-43 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR ALX04_RS03040 7741dc1f2e9b1eb49b0b3cf130e7650d 242 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 6 23 2.2E-43 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR ALX04_RS03040 7741dc1f2e9b1eb49b0b3cf130e7650d 242 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 152 171 2.2E-43 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR ALX04_RS03040 7741dc1f2e9b1eb49b0b3cf130e7650d 242 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 126 142 2.2E-43 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR ALX04_RS03040 7741dc1f2e9b1eb49b0b3cf130e7650d 242 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 206 226 2.2E-43 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR ALX04_RS03040 7741dc1f2e9b1eb49b0b3cf130e7650d 242 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 132 140 1.7E-14 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR ALX04_RS03040 7741dc1f2e9b1eb49b0b3cf130e7650d 242 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 152 171 1.7E-14 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR ALX04_RS03040 7741dc1f2e9b1eb49b0b3cf130e7650d 242 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 79 90 1.7E-14 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR ALX04_RS03040 7741dc1f2e9b1eb49b0b3cf130e7650d 242 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 11 241 1.4E-62 T 28-03-2018 ALX04_RS03040 7741dc1f2e9b1eb49b0b3cf130e7650d 242 SUPERFAMILY SSF51735 5 242 4.05E-75 T 28-03-2018 IPR016040 NAD(P)-binding domain ALX04_RS03040 7741dc1f2e9b1eb49b0b3cf130e7650d 242 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 5 208 2.3E-6 T 28-03-2018 ALX04_RS03040 7741dc1f2e9b1eb49b0b3cf130e7650d 242 Gene3D G3DSA:3.40.50.720 3 242 1.9E-71 T 28-03-2018 ALX04_RS03040 7741dc1f2e9b1eb49b0b3cf130e7650d 242 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 139 167 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 ALX04_RS11140 5a991f2673e79507b819de0d1bb8f140 316 TIGRFAM TIGR00274 TIGR00274: N-acetylmuramic acid 6-phosphate etherase 24 313 6.5E-116 T 28-03-2018 IPR005488 N-acetylmuramic acid 6-phosphate etherase MurQ GO:0016835|GO:0046348 KEGG: 00030+4.2.1.12|KEGG: 00520+4.2.1.126 ALX04_RS11140 5a991f2673e79507b819de0d1bb8f140 316 Gene3D G3DSA:3.40.50.10490 28 260 4.4E-48 T 28-03-2018 ALX04_RS11140 5a991f2673e79507b819de0d1bb8f140 316 Gene3D G3DSA:1.10.8.10 287 314 7.2E-5 T 28-03-2018 ALX04_RS11140 5a991f2673e79507b819de0d1bb8f140 316 Gene3D G3DSA:1.10.8.10 261 286 1.9E-5 T 28-03-2018 ALX04_RS11140 5a991f2673e79507b819de0d1bb8f140 316 Pfam PF13580 SIS domain 56 182 2.7E-9 T 28-03-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 ALX04_RS11140 5a991f2673e79507b819de0d1bb8f140 316 ProSitePatterns PS01272 Glucokinase regulatory protein family signature. 203 220 - T 28-03-2018 IPR005486 Glucokinase regulatory protein, conserved site KEGG: 00030+4.2.1.12|KEGG: 00520+4.2.1.126|Reactome: R-HSA-170822|Reactome: R-HSA-5619107 ALX04_RS11140 5a991f2673e79507b819de0d1bb8f140 316 SUPERFAMILY SSF53697 23 266 2.45E-64 T 28-03-2018 ALX04_RS11140 5a991f2673e79507b819de0d1bb8f140 316 Hamap MF_00068 N-acetylmuramic acid 6-phosphate etherase [murQ]. 20 313 41.955 T 28-03-2018 IPR005488 N-acetylmuramic acid 6-phosphate etherase MurQ GO:0016835|GO:0046348 KEGG: 00030+4.2.1.12|KEGG: 00520+4.2.1.126 ALX04_RS05480 3c84b23cbd4cb332c16c25e52ea240b4 288 ProSitePatterns PS00211 ABC transporters family signature. 121 135 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 ALX04_RS05480 3c84b23cbd4cb332c16c25e52ea240b4 288 SMART SM00382 27 205 4.9E-18 T 28-03-2018 IPR003593 AAA+ ATPase domain ALX04_RS05480 3c84b23cbd4cb332c16c25e52ea240b4 288 Gene3D G3DSA:3.40.50.300 1 231 2.5E-62 T 28-03-2018 ALX04_RS05480 3c84b23cbd4cb332c16c25e52ea240b4 288 SUPERFAMILY SSF52540 2 212 3.97E-61 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase ALX04_RS05480 3c84b23cbd4cb332c16c25e52ea240b4 288 Pfam PF00005 ABC transporter 19 148 2.1E-33 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 ALX04_RS09980 e65186b0a97704b2a01fbb501fe77850 641 ProSitePatterns PS01035 PTS EIIB domains cysteine phosphorylation site signature. 20 37 - T 28-03-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 ALX04_RS09980 e65186b0a97704b2a01fbb501fe77850 641 Pfam PF02378 Phosphotransferase system, EIIC 114 405 6.9E-33 T 28-03-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 ALX04_RS09980 e65186b0a97704b2a01fbb501fe77850 641 Gene3D G3DSA:3.30.1360.60 4 78 7.4E-26 T 28-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 ALX04_RS09980 e65186b0a97704b2a01fbb501fe77850 641 Pfam PF00358 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 481 608 1.2E-48 T 28-03-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 ALX04_RS09980 e65186b0a97704b2a01fbb501fe77850 641 Pfam PF00367 phosphotransferase system, EIIB 10 42 3.5E-13 T 28-03-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 ALX04_RS09980 e65186b0a97704b2a01fbb501fe77850 641 TIGRFAM TIGR01996 PTS-II-BC-sucr: PTS system, sucrose-specific IIBC component 4 461 5.5E-175 T 28-03-2018 IPR010973 Phosphotransferase system, sucrose-specific IIBC component GO:0008982|GO:0009401|GO:0016021 ALX04_RS09980 e65186b0a97704b2a01fbb501fe77850 641 SUPERFAMILY SSF55604 9 81 4.97E-18 T 28-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 ALX04_RS09980 e65186b0a97704b2a01fbb501fe77850 641 ProSitePatterns PS00371 PTS EIIA domains phosphorylation site signature 1. 547 559 - T 28-03-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 ALX04_RS09980 e65186b0a97704b2a01fbb501fe77850 641 SUPERFAMILY SSF51261 481 619 9.94E-50 T 28-03-2018 IPR011055 Duplicated hybrid motif ALX04_RS09980 e65186b0a97704b2a01fbb501fe77850 641 TIGRFAM TIGR00830 PTBA: PTS system, glucose subfamily, IIA component 482 605 2.4E-41 T 28-03-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 ALX04_RS09980 e65186b0a97704b2a01fbb501fe77850 641 Gene3D G3DSA:2.70.70.10 468 631 8.6E-56 T 28-03-2018 ALX04_RS11815 ef906748f97b800d12b2dedf9c47dd54 281 Pfam PF06314 Acetoacetate decarboxylase (ADC) 21 248 8.3E-46 T 28-03-2018 IPR010451 Acetoacetate decarboxylase GO:0016829 KEGG: 00072+4.1.1.4|KEGG: 00640+4.1.1.4|MetaCyc: PWY-5451|MetaCyc: PWY-6588|MetaCyc: PWY-6876|MetaCyc: PWY-7466 ALX04_RS11815 ef906748f97b800d12b2dedf9c47dd54 281 Gene3D G3DSA:2.40.400.10 8 246 7.1E-32 T 28-03-2018 IPR023375 Acetoacetate decarboxylase beta barrel domain KEGG: 00072+4.1.1.4|KEGG: 00640+4.1.1.4|MetaCyc: PWY-5451|MetaCyc: PWY-6588|MetaCyc: PWY-6876|MetaCyc: PWY-7466 ALX04_RS11815 ef906748f97b800d12b2dedf9c47dd54 281 SUPERFAMILY SSF160104 2 250 8.76E-46 T 28-03-2018 IPR023375 Acetoacetate decarboxylase beta barrel domain KEGG: 00072+4.1.1.4|KEGG: 00640+4.1.1.4|MetaCyc: PWY-5451|MetaCyc: PWY-6588|MetaCyc: PWY-6876|MetaCyc: PWY-7466 ALX04_RS04525 9b7d62adaabf1ac7226c86219a744bdf 199 Gene3D G3DSA:2.30.22.10 142 199 8.9E-24 T 28-03-2018 IPR009012 GrpE nucleotide exchange factor, head GO:0006457 Reactome: R-HSA-1268020 ALX04_RS04525 9b7d62adaabf1ac7226c86219a744bdf 199 SUPERFAMILY SSF58014 50 142 5.49E-24 T 28-03-2018 ALX04_RS04525 9b7d62adaabf1ac7226c86219a744bdf 199 Hamap MF_01151 Protein GrpE [grpE]. 11 199 20.498 T 28-03-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 ALX04_RS04525 9b7d62adaabf1ac7226c86219a744bdf 199 PRINTS PR00773 GrpE protein signature 68 84 8.4E-29 T 28-03-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 ALX04_RS04525 9b7d62adaabf1ac7226c86219a744bdf 199 PRINTS PR00773 GrpE protein signature 96 111 8.4E-29 T 28-03-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 ALX04_RS04525 9b7d62adaabf1ac7226c86219a744bdf 199 PRINTS PR00773 GrpE protein signature 178 197 8.4E-29 T 28-03-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 ALX04_RS04525 9b7d62adaabf1ac7226c86219a744bdf 199 PRINTS PR00773 GrpE protein signature 150 165 8.4E-29 T 28-03-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 ALX04_RS04525 9b7d62adaabf1ac7226c86219a744bdf 199 Gene3D G3DSA:3.90.20.20 21 141 3.0E-23 T 28-03-2018 IPR013805 GrpE nucleotide exchange factor, coiled-coil Reactome: R-HSA-1268020 ALX04_RS04525 9b7d62adaabf1ac7226c86219a744bdf 199 SUPERFAMILY SSF51064 143 199 3.53E-18 T 28-03-2018 IPR009012 GrpE nucleotide exchange factor, head GO:0006457 Reactome: R-HSA-1268020 ALX04_RS04525 9b7d62adaabf1ac7226c86219a744bdf 199 ProSitePatterns PS01071 grpE protein signature. 153 197 - T 28-03-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 ALX04_RS04525 9b7d62adaabf1ac7226c86219a744bdf 199 Pfam PF01025 GrpE 38 199 5.1E-52 T 28-03-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 ALX04_RS14525 319eb6efe9566315cd98fa307830d0b9 224 Gene3D G3DSA:3.40.50.2020 41 224 4.2E-25 T 28-03-2018 ALX04_RS14525 319eb6efe9566315cd98fa307830d0b9 224 Pfam PF00156 Phosphoribosyl transferase domain 167 222 5.0E-10 T 28-03-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 ALX04_RS14525 319eb6efe9566315cd98fa307830d0b9 224 SUPERFAMILY SSF53271 79 223 2.05E-24 T 28-03-2018 IPR029057 Phosphoribosyltransferase-like ALX04_RS00195 a57a0f9b39fbbeac20c9ee010a1f75f0 380 Gene3D G3DSA:1.25.40.10 25 380 8.0E-6 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 ALX04_RS06100 9664d2f3f8f57e6b4716fdcf2dafec00 519 SUPERFAMILY SSF109604 314 466 4.49E-29 T 28-03-2018 ALX04_RS06100 9664d2f3f8f57e6b4716fdcf2dafec00 519 SUPERFAMILY SSF54791 207 303 3.8E-17 T 28-03-2018 IPR004088 K Homology domain, type 1 GO:0003723 ALX04_RS06100 9664d2f3f8f57e6b4716fdcf2dafec00 519 Pfam PF12072 Domain of unknown function (DUF3552) 6 204 6.4E-69 T 28-03-2018 IPR022711 Ribonuclease Y, N-terminal ALX04_RS06100 9664d2f3f8f57e6b4716fdcf2dafec00 519 SMART SM00471 331 437 1.4E-12 T 28-03-2018 IPR003607 HD/PDEase domain ALX04_RS06100 9664d2f3f8f57e6b4716fdcf2dafec00 519 Pfam PF01966 HD domain 335 427 3.4E-18 T 28-03-2018 IPR006674 HD domain ALX04_RS06100 9664d2f3f8f57e6b4716fdcf2dafec00 519 TIGRFAM TIGR03319 RNase_Y: ribonuclease Y 6 519 5.3E-242 T 28-03-2018 IPR017705 Ribonuclease Y GO:0003723|GO:0006402|GO:0016020 ALX04_RS06100 9664d2f3f8f57e6b4716fdcf2dafec00 519 Gene3D G3DSA:1.10.3210.10 243 458 5.6E-34 T 28-03-2018 ALX04_RS06100 9664d2f3f8f57e6b4716fdcf2dafec00 519 Hamap MF_00335 Ribonuclease Y [rny]. 4 519 25.24 T 28-03-2018 IPR017705 Ribonuclease Y GO:0003723|GO:0006402|GO:0016020 ALX04_RS06100 9664d2f3f8f57e6b4716fdcf2dafec00 519 TIGRFAM TIGR00277 HDIG: HDIG domain 331 408 1.8E-25 T 28-03-2018 IPR006675 HDIG domain ALX04_RS06100 9664d2f3f8f57e6b4716fdcf2dafec00 519 Pfam PF00013 KH domain 212 270 4.7E-7 T 28-03-2018 IPR004088 K Homology domain, type 1 GO:0003723 ALX04_RS06100 9664d2f3f8f57e6b4716fdcf2dafec00 519 Gene3D G3DSA:3.30.300.20 98 242 7.0E-11 T 28-03-2018 IPR015946 K homology domain-like, alpha/beta ALX04_RS06100 9664d2f3f8f57e6b4716fdcf2dafec00 519 SMART SM00322 207 274 2.0E-8 T 28-03-2018 IPR004087 K Homology domain GO:0003676 ALX04_RS13650 bf9e1d2a2b350d1fe6f6978947707a8c 299 TIGRFAM TIGR00718 sda_alpha: L-serine dehydratase, iron-sulfur-dependent, alpha subunit 1 293 7.5E-120 T 28-03-2018 IPR004642 Serine dehydratase, alpha subunit GO:0003941|GO:0006094 KEGG: 00260+4.3.1.17|KEGG: 00270+4.3.1.17 ALX04_RS13650 bf9e1d2a2b350d1fe6f6978947707a8c 299 Gene3D G3DSA:1.10.4100.10 11 253 1.4E-26 T 28-03-2018 ALX04_RS13650 bf9e1d2a2b350d1fe6f6978947707a8c 299 Pfam PF03313 Serine dehydratase alpha chain 16 276 1.2E-71 T 28-03-2018 IPR005130 Serine dehydratase-like, alpha subunit ALX04_RS12205 1e3bedeb6b8c615137f9e670072e6e20 186 Hamap MF_01572 UPF0397 protein . 5 185 26.749 T 28-03-2018 IPR022914 Protein of unknown function UPF0397 ALX04_RS12205 1e3bedeb6b8c615137f9e670072e6e20 186 Pfam PF07155 ECF-type riboflavin transporter, S component 7 173 1.8E-47 T 28-03-2018 IPR009825 ECF transporter, substrate-specific component-like GO:0016020 ALX04_RS11675 5fd48568b19dd193e045dbf3ee6a3993 605 Pfam PF00128 Alpha amylase, catalytic domain 188 495 1.1E-61 T 28-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 ALX04_RS11675 5fd48568b19dd193e045dbf3ee6a3993 605 SMART SM00642 138 521 5.4E-82 T 28-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 ALX04_RS11675 5fd48568b19dd193e045dbf3ee6a3993 605 Gene3D G3DSA:2.60.40.10 1 115 4.6E-10 T 28-03-2018 IPR013783 Immunoglobulin-like fold ALX04_RS11675 5fd48568b19dd193e045dbf3ee6a3993 605 SUPERFAMILY SSF51445 77 527 4.7E-93 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily ALX04_RS11675 5fd48568b19dd193e045dbf3ee6a3993 605 Gene3D G3DSA:3.20.20.80 124 529 2.1E-88 T 28-03-2018 ALX04_RS10915 ba535b95f08f099bf0c1e65baf17387a 195 SUPERFAMILY SSF48498 100 192 1.23E-8 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal ALX04_RS10915 ba535b95f08f099bf0c1e65baf17387a 195 Pfam PF00440 Bacterial regulatory proteins, tetR family 13 56 1.4E-6 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 ALX04_RS10915 ba535b95f08f099bf0c1e65baf17387a 195 Gene3D G3DSA:1.10.10.60 45 65 9.0E-4 T 28-03-2018 ALX04_RS10915 ba535b95f08f099bf0c1e65baf17387a 195 Gene3D G3DSA:1.10.357.10 66 195 1.0E-7 T 28-03-2018 ALX04_RS10915 ba535b95f08f099bf0c1e65baf17387a 195 Gene3D G3DSA:1.10.10.60 3 44 8.7E-9 T 28-03-2018 ALX04_RS10915 ba535b95f08f099bf0c1e65baf17387a 195 SUPERFAMILY SSF46689 4 76 1.9E-11 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 ALX04_RS14445 b1be2582d366b099ddf69913e1f40f36 350 Gene3D G3DSA:3.40.190.10 142 259 2.2E-12 T 28-03-2018 ALX04_RS14445 b1be2582d366b099ddf69913e1f40f36 350 Pfam PF12974 ABC transporter, phosphonate, periplasmic substrate-binding protein 46 317 1.1E-46 T 28-03-2018 ALX04_RS14445 b1be2582d366b099ddf69913e1f40f36 350 Gene3D G3DSA:3.40.190.10 28 141 1.5E-7 T 28-03-2018 ALX04_RS14445 b1be2582d366b099ddf69913e1f40f36 350 SUPERFAMILY SSF53850 62 340 4.49E-38 T 28-03-2018 ALX04_RS08835 9e1ba626c82d8a6d2fb3244ba7bc3922 298 Gene3D G3DSA:3.40.50.1820 2 296 9.2E-45 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold ALX04_RS08835 9e1ba626c82d8a6d2fb3244ba7bc3922 298 SUPERFAMILY SSF53474 8 292 1.3E-50 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold ALX04_RS08835 9e1ba626c82d8a6d2fb3244ba7bc3922 298 PIRSF PIRSF005539 1 298 1.4E-99 T 28-03-2018 IPR005945 Proline-specific peptidase GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 ALX04_RS08835 9e1ba626c82d8a6d2fb3244ba7bc3922 298 Pfam PF00561 alpha/beta hydrolase fold 29 280 1.0E-22 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 ALX04_RS08835 9e1ba626c82d8a6d2fb3244ba7bc3922 298 TIGRFAM TIGR01250 pro_imino_pep_2: proline-specific peptidase 3 292 8.2E-95 T 28-03-2018 IPR005945 Proline-specific peptidase GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 ALX04_RS08835 9e1ba626c82d8a6d2fb3244ba7bc3922 298 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 57 68 2.1E-11 T 28-03-2018 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 ALX04_RS08835 9e1ba626c82d8a6d2fb3244ba7bc3922 298 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 106 120 2.1E-11 T 28-03-2018 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 ALX04_RS08835 9e1ba626c82d8a6d2fb3244ba7bc3922 298 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 29 37 2.1E-11 T 28-03-2018 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 ALX04_RS02290 a54009f4e367172e83bab99a1b5b013a 112 SUPERFAMILY SSF117916 13 109 8.5E-31 T 28-03-2018 IPR034904 Fe-S cluster assembly domain ALX04_RS02290 a54009f4e367172e83bab99a1b5b013a 112 Pfam PF01883 Iron-sulfur cluster assembly protein 15 85 5.0E-19 T 28-03-2018 IPR002744 MIP18 family-like ALX04_RS02290 a54009f4e367172e83bab99a1b5b013a 112 Gene3D G3DSA:3.30.300.130 12 110 4.3E-24 T 28-03-2018 IPR034904 Fe-S cluster assembly domain ALX04_RS11200 efa7c85e7698fa1d861af2d30a299737 473 Pfam PF07690 Major Facilitator Superfamily 40 422 3.2E-22 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 ALX04_RS11200 efa7c85e7698fa1d861af2d30a299737 473 Gene3D G3DSA:1.20.1250.20 13 243 9.7E-21 T 28-03-2018 ALX04_RS11200 efa7c85e7698fa1d861af2d30a299737 473 SUPERFAMILY SSF103473 34 465 2.88E-41 T 28-03-2018 IPR020846 Major facilitator superfamily domain ALX04_RS11200 efa7c85e7698fa1d861af2d30a299737 473 Gene3D G3DSA:1.20.1250.20 254 473 3.2E-21 T 28-03-2018 ALX04_RS08880 210ae17e0d0659fa8690776e54fd5d09 376 Gene3D G3DSA:3.30.70.270 195 376 1.7E-42 T 28-03-2018 ALX04_RS08880 210ae17e0d0659fa8690776e54fd5d09 376 SMART SM00267 201 376 1.6E-28 T 28-03-2018 IPR000160 GGDEF domain ALX04_RS08880 210ae17e0d0659fa8690776e54fd5d09 376 SUPERFAMILY SSF55073 217 374 3.22E-36 T 28-03-2018 IPR029787 Nucleotide cyclase ALX04_RS08880 210ae17e0d0659fa8690776e54fd5d09 376 Pfam PF00990 Diguanylate cyclase, GGDEF domain 212 372 9.5E-32 T 28-03-2018 IPR000160 GGDEF domain ALX04_RS08880 210ae17e0d0659fa8690776e54fd5d09 376 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 209 375 1.3E-35 T 28-03-2018 IPR000160 GGDEF domain ALX04_RS00740 b0f7c70c53a79f0c6abc10e5a0a9b9a3 460 Gene3D G3DSA:1.10.275.10 2 135 1.8E-45 T 28-03-2018 IPR024083 Fumarase/histidase, N-terminal ALX04_RS00740 b0f7c70c53a79f0c6abc10e5a0a9b9a3 460 Pfam PF00206 Lyase 12 338 4.9E-93 T 28-03-2018 IPR022761 Fumarate lyase, N-terminal ALX04_RS00740 b0f7c70c53a79f0c6abc10e5a0a9b9a3 460 Pfam PF10415 Fumarase C C-terminus 405 457 3.1E-19 T 28-03-2018 IPR018951 Fumarase C, C-terminal GO:0006099|GO:0016829 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384|Reactome: R-HSA-71403 ALX04_RS00740 b0f7c70c53a79f0c6abc10e5a0a9b9a3 460 ProSitePatterns PS00163 Fumarate lyases signature. 313 322 - T 28-03-2018 IPR020557 Fumarate lyase, conserved site GO:0003824 ALX04_RS00740 b0f7c70c53a79f0c6abc10e5a0a9b9a3 460 Gene3D G3DSA:1.10.40.30 414 457 1.0E-19 T 28-03-2018 ALX04_RS00740 b0f7c70c53a79f0c6abc10e5a0a9b9a3 460 PRINTS PR00149 Fumarate lyase superfamily signature 131 149 7.5E-31 T 28-03-2018 IPR000362 Fumarate lyase family ALX04_RS00740 b0f7c70c53a79f0c6abc10e5a0a9b9a3 460 PRINTS PR00149 Fumarate lyase superfamily signature 267 294 7.5E-31 T 28-03-2018 IPR000362 Fumarate lyase family ALX04_RS00740 b0f7c70c53a79f0c6abc10e5a0a9b9a3 460 PRINTS PR00149 Fumarate lyase superfamily signature 313 329 7.5E-31 T 28-03-2018 IPR000362 Fumarate lyase family ALX04_RS00740 b0f7c70c53a79f0c6abc10e5a0a9b9a3 460 PRINTS PR00149 Fumarate lyase superfamily signature 176 194 7.5E-31 T 28-03-2018 IPR000362 Fumarate lyase family ALX04_RS00740 b0f7c70c53a79f0c6abc10e5a0a9b9a3 460 SUPERFAMILY SSF48557 1 452 3.61E-132 T 28-03-2018 IPR008948 L-Aspartase-like GO:0003824 ALX04_RS00740 b0f7c70c53a79f0c6abc10e5a0a9b9a3 460 Hamap MF_00743 Fumarate hydratase class II [fumC]. 4 458 71.585 T 28-03-2018 IPR005677 Fumarate hydratase, class II GO:0004333|GO:0006106|GO:0045239 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384|Reactome: R-HSA-71403 ALX04_RS00740 b0f7c70c53a79f0c6abc10e5a0a9b9a3 460 Gene3D G3DSA:1.20.200.10 136 413 1.4E-78 T 28-03-2018 ALX04_RS05195 21fbdb8865010306d038907982107b7a 197 Gene3D G3DSA:3.40.50.300 73 194 2.0E-16 T 28-03-2018 ALX04_RS05195 21fbdb8865010306d038907982107b7a 197 Hamap MF_00321 Probable GTP-binding protein EngB [engB]. 11 193 28.118 T 28-03-2018 IPR019987 GTP-binding protein, ribosome biogenesis, YsxC GO:0005525 ALX04_RS05195 21fbdb8865010306d038907982107b7a 197 Gene3D G3DSA:3.40.50.300 4 72 3.3E-12 T 28-03-2018 ALX04_RS05195 21fbdb8865010306d038907982107b7a 197 Pfam PF01926 50S ribosome-binding GTPase 25 143 4.9E-23 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 ALX04_RS05195 21fbdb8865010306d038907982107b7a 197 SUPERFAMILY SSF52540 1 191 8.27E-40 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase ALX04_RS05195 21fbdb8865010306d038907982107b7a 197 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 25 190 1.3E-15 T 28-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 ALX04_RS05195 21fbdb8865010306d038907982107b7a 197 TIGRFAM TIGR03598 GTPase_YsxC: ribosome biogenesis GTP-binding protein YsxC 7 189 1.2E-72 T 28-03-2018 IPR019987 GTP-binding protein, ribosome biogenesis, YsxC GO:0005525 ALX04_RS14800 5fea08ab9873961c60506478a7445fe8 156 Pfam PF01668 SmpB protein 14 155 1.4E-60 T 28-03-2018 IPR000037 SsrA-binding protein GO:0003723 ALX04_RS14800 5fea08ab9873961c60506478a7445fe8 156 SUPERFAMILY SSF74982 8 136 2.62E-50 T 28-03-2018 IPR023620 Small protein B ALX04_RS14800 5fea08ab9873961c60506478a7445fe8 156 Hamap MF_00023 SsrA-binding protein [smpB]. 1 156 70.443 T 28-03-2018 IPR000037 SsrA-binding protein GO:0003723 ALX04_RS14800 5fea08ab9873961c60506478a7445fe8 156 TIGRFAM TIGR00086 smpB: SsrA-binding protein 13 154 3.3E-56 T 28-03-2018 IPR000037 SsrA-binding protein GO:0003723 ALX04_RS14800 5fea08ab9873961c60506478a7445fe8 156 ProDom PD004488 SSRA-BINDING RNA-BINDING SMPB SMALL B TMRNA-BINDING SSRA 3D-STRUCTURE HOMOLOG BINDING 14 136 6.0E-68 T 28-03-2018 IPR000037 SsrA-binding protein GO:0003723 ALX04_RS14800 5fea08ab9873961c60506478a7445fe8 156 Gene3D G3DSA:2.40.280.10 13 131 5.3E-49 T 28-03-2018 IPR023620 Small protein B ALX04_RS14800 5fea08ab9873961c60506478a7445fe8 156 ProSitePatterns PS01317 SsrA-binding protein. 31 43 - T 28-03-2018 IPR020081 SsrA-binding protein, conserved site ALX04_RS11320 6494b46c7ab358ed41b2699389b16680 358 SUPERFAMILY SSF53822 81 355 8.16E-58 T 28-03-2018 IPR028082 Periplasmic binding protein-like I ALX04_RS11320 6494b46c7ab358ed41b2699389b16680 358 Pfam PF00392 Bacterial regulatory proteins, gntR family 4 67 4.4E-17 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 ALX04_RS11320 6494b46c7ab358ed41b2699389b16680 358 Pfam PF13377 Periplasmic binding protein-like domain 194 354 3.1E-26 T 28-03-2018 ALX04_RS11320 6494b46c7ab358ed41b2699389b16680 358 Gene3D G3DSA:1.10.10.10 1 69 4.1E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS11320 6494b46c7ab358ed41b2699389b16680 358 Gene3D G3DSA:3.40.50.2300 199 358 7.3E-31 T 28-03-2018 ALX04_RS11320 6494b46c7ab358ed41b2699389b16680 358 SMART SM00345 8 67 1.2E-16 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 ALX04_RS11320 6494b46c7ab358ed41b2699389b16680 358 Gene3D G3DSA:3.40.50.2300 81 198 1.5E-22 T 28-03-2018 ALX04_RS11320 6494b46c7ab358ed41b2699389b16680 358 SUPERFAMILY SSF46785 3 94 4.51E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS11320 6494b46c7ab358ed41b2699389b16680 358 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 27 41 1.7E-6 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 ALX04_RS11320 6494b46c7ab358ed41b2699389b16680 358 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 41 57 1.7E-6 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 ALX04_RS13205 7cea859f4d2b827e1ec4625aeac065de 240 Pfam PF00230 Major intrinsic protein 9 236 9.0E-45 T 28-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 ALX04_RS13205 7cea859f4d2b827e1ec4625aeac065de 240 ProSitePatterns PS00221 MIP family signature. 68 76 - T 28-03-2018 IPR022357 Major intrinsic protein, conserved site GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 ALX04_RS13205 7cea859f4d2b827e1ec4625aeac065de 240 Gene3D G3DSA:1.20.1080.10 1 240 3.6E-83 T 28-03-2018 IPR023271 Aquaporin-like Reactome: R-HSA-432047 ALX04_RS13205 7cea859f4d2b827e1ec4625aeac065de 240 TIGRFAM TIGR00861 MIP: MIP family channel proteins 12 236 5.5E-56 T 28-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 ALX04_RS13205 7cea859f4d2b827e1ec4625aeac065de 240 PRINTS PR00783 Major intrinsic protein family signature 50 74 1.0E-46 T 28-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 ALX04_RS13205 7cea859f4d2b827e1ec4625aeac065de 240 PRINTS PR00783 Major intrinsic protein family signature 219 239 1.0E-46 T 28-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 ALX04_RS13205 7cea859f4d2b827e1ec4625aeac065de 240 PRINTS PR00783 Major intrinsic protein family signature 142 160 1.0E-46 T 28-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 ALX04_RS13205 7cea859f4d2b827e1ec4625aeac065de 240 PRINTS PR00783 Major intrinsic protein family signature 172 194 1.0E-46 T 28-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 ALX04_RS13205 7cea859f4d2b827e1ec4625aeac065de 240 PRINTS PR00783 Major intrinsic protein family signature 87 106 1.0E-46 T 28-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 ALX04_RS13205 7cea859f4d2b827e1ec4625aeac065de 240 PRINTS PR00783 Major intrinsic protein family signature 8 27 1.0E-46 T 28-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 ALX04_RS13205 7cea859f4d2b827e1ec4625aeac065de 240 SUPERFAMILY SSF81338 7 239 1.57E-70 T 28-03-2018 IPR023271 Aquaporin-like Reactome: R-HSA-432047 ALX04_RS09875 4d8d63b74998f2952aafd9d3fc5d0130 383 Gene3D G3DSA:3.20.20.70 5 377 1.3E-104 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 ALX04_RS09875 4d8d63b74998f2952aafd9d3fc5d0130 383 SUPERFAMILY SSF51412 8 379 3.01E-137 T 28-03-2018 ALX04_RS09875 4d8d63b74998f2952aafd9d3fc5d0130 383 SMART SM01240 11 368 5.7E-234 T 28-03-2018 ALX04_RS09875 4d8d63b74998f2952aafd9d3fc5d0130 383 Pfam PF00478 IMP dehydrogenase / GMP reductase domain 12 368 4.2E-151 T 28-03-2018 IPR001093 IMP dehydrogenase/GMP reductase GO:0003824|GO:0055114 ALX04_RS09875 4d8d63b74998f2952aafd9d3fc5d0130 383 ProSitePatterns PS00487 IMP dehydrogenase / GMP reductase signature. 187 199 - T 28-03-2018 IPR015875 IMP dehydrogenase / GMP reductase, conserved site GO:0016491|GO:0055114 ALX04_RS16065 c49ee38dad00d0216dc150a67d577b24 183 SUPERFAMILY SSF53098 13 177 7.21E-24 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 ALX04_RS16065 c49ee38dad00d0216dc150a67d577b24 183 Pfam PF00665 Integrase core domain 20 135 3.7E-21 T 28-03-2018 IPR001584 Integrase, catalytic core GO:0015074 ALX04_RS16065 c49ee38dad00d0216dc150a67d577b24 183 Gene3D G3DSA:3.30.420.10 15 183 1.1E-28 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 ALX04_RS11995 e8508968104fcad5621342ac190b5b96 221 SUPERFAMILY SSF51206 8 139 2.21E-22 T 28-03-2018 IPR018490 Cyclic nucleotide-binding-like ALX04_RS11995 e8508968104fcad5621342ac190b5b96 221 Gene3D G3DSA:1.10.10.10 132 220 4.5E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS11995 e8508968104fcad5621342ac190b5b96 221 SUPERFAMILY SSF46785 141 219 3.47E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS11995 e8508968104fcad5621342ac190b5b96 221 SMART SM00419 162 211 2.3E-6 T 28-03-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 ALX04_RS11995 e8508968104fcad5621342ac190b5b96 221 Gene3D G3DSA:2.60.120.10 4 131 8.3E-7 T 28-03-2018 IPR014710 RmlC-like jelly roll fold ALX04_RS11995 e8508968104fcad5621342ac190b5b96 221 ProSitePatterns PS00042 Crp-type HTH domain signature. 170 194 - T 28-03-2018 IPR018335 Transcription regulator HTH, Crp-type, conserved site GO:0003700|GO:0005622|GO:0006355 ALX04_RS11995 e8508968104fcad5621342ac190b5b96 221 Pfam PF13545 Crp-like helix-turn-helix domain 144 216 2.0E-12 T 28-03-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 ALX04_RS01395 791dabbe8e16844bb805240072059595 183 Pfam PF00589 Phage integrase family 12 165 1.1E-21 T 28-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 ALX04_RS01395 791dabbe8e16844bb805240072059595 183 SUPERFAMILY SSF56349 9 172 5.0E-32 T 28-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 ALX04_RS01395 791dabbe8e16844bb805240072059595 183 Gene3D G3DSA:1.10.443.10 7 174 5.7E-28 T 28-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 ALX04_RS07225 2018643827340589a14a2218671b0681 291 Gene3D G3DSA:3.40.50.880 26 290 1.8E-29 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like ALX04_RS07225 2018643827340589a14a2218671b0681 291 ProDom PD037892 HOMOSERINE O-SUCCINYLTRANSFERASE TRANSFERASE ACYLTRANSFERASE BIOSYNTHESIS TRANSSUCCINYLASE HTS METHIONINE O- AMINO-ACID 29 289 6.0E-153 T 28-03-2018 ALX04_RS07225 2018643827340589a14a2218671b0681 291 Pfam PF04204 Homoserine O-succinyltransferase 23 282 4.2E-81 T 28-03-2018 IPR033752 MetA family KEGG: 00270+2.3.1.46|KEGG: 00920+2.3.1.46 ALX04_RS07225 2018643827340589a14a2218671b0681 291 SUPERFAMILY SSF52317 23 282 7.44E-65 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like ALX04_RS07225 2018643827340589a14a2218671b0681 291 PIRSF PIRSF000450 15 288 8.3E-78 T 28-03-2018 IPR033752 MetA family KEGG: 00270+2.3.1.46|KEGG: 00920+2.3.1.46 ALX04_RS06430 1b4b5d68d318d03c742063e774bbadd3 171 Pfam PF00430 ATP synthase B/B' CF(0) 21 146 5.7E-34 T 28-03-2018 IPR002146 ATP synthase, F0 complex, subunit b/b', bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 ALX04_RS06430 1b4b5d68d318d03c742063e774bbadd3 171 Hamap MF_01398 ATP synthase subunit b [atpF]. 11 148 12.918 T 28-03-2018 IPR002146 ATP synthase, F0 complex, subunit b/b', bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 ALX04_RS06430 1b4b5d68d318d03c742063e774bbadd3 171 TIGRFAM TIGR01144 ATP_synt_b: ATP synthase F0, B subunit 22 164 2.4E-36 T 28-03-2018 IPR005864 ATP synthase, F0 complex, subunit b, bacterial GO:0015078|GO:0015986|GO:0045263 ALX04_RS06430 1b4b5d68d318d03c742063e774bbadd3 171 SUPERFAMILY SSF81573 73 130 4.71E-10 T 28-03-2018 IPR028987 F-type ATP synthase subunit B-like, membrane domain ALX04_RS06430 1b4b5d68d318d03c742063e774bbadd3 171 Gene3D G3DSA:1.20.5.620 72 132 2.5E-8 T 28-03-2018 IPR028987 F-type ATP synthase subunit B-like, membrane domain ALX04_RS03840 b67155210a673ee9fdc5d80226308365 492 SUPERFAMILY SSF47090 405 466 7.59E-16 T 28-03-2018 IPR002477 Peptidoglycan binding-like ALX04_RS03840 b67155210a673ee9fdc5d80226308365 492 Gene3D G3DSA:2.30.42.10 124 203 5.4E-21 T 28-03-2018 ALX04_RS03840 b67155210a673ee9fdc5d80226308365 492 Gene3D G3DSA:3.30.750.44 46 123 8.7E-17 T 28-03-2018 ALX04_RS03840 b67155210a673ee9fdc5d80226308365 492 Pfam PF01471 Putative peptidoglycan binding domain 412 465 7.2E-17 T 28-03-2018 IPR002477 Peptidoglycan binding-like ALX04_RS03840 b67155210a673ee9fdc5d80226308365 492 Pfam PF03572 Peptidase family S41 222 387 2.1E-49 T 28-03-2018 IPR005151 Tail specific protease GO:0006508|GO:0008236 Reactome: R-HSA-2187335|Reactome: R-HSA-2453902 ALX04_RS03840 b67155210a673ee9fdc5d80226308365 492 SMART SM00228 124 195 9.7E-17 T 28-03-2018 IPR001478 PDZ domain GO:0005515 ALX04_RS03840 b67155210a673ee9fdc5d80226308365 492 Pfam PF13180 PDZ domain 125 203 4.0E-14 T 28-03-2018 IPR001478 PDZ domain GO:0005515 ALX04_RS03840 b67155210a673ee9fdc5d80226308365 492 SMART SM00245 195 389 1.6E-59 T 28-03-2018 IPR005151 Tail specific protease GO:0006508|GO:0008236 Reactome: R-HSA-2187335|Reactome: R-HSA-2453902 ALX04_RS03840 b67155210a673ee9fdc5d80226308365 492 Gene3D G3DSA:1.10.101.10 401 477 6.0E-18 T 28-03-2018 IPR002477 Peptidoglycan binding-like ALX04_RS03840 b67155210a673ee9fdc5d80226308365 492 SUPERFAMILY SSF50156 118 207 3.97E-19 T 28-03-2018 IPR001478 PDZ domain GO:0005515 ALX04_RS03840 b67155210a673ee9fdc5d80226308365 492 Gene3D G3DSA:3.90.226.10 204 400 1.3E-58 T 28-03-2018 ALX04_RS03840 b67155210a673ee9fdc5d80226308365 492 TIGRFAM TIGR00225 prc: C-terminal processing peptidase 76 394 1.5E-105 T 28-03-2018 IPR004447 C-terminal-processing peptidase S41A GO:0006508|GO:0008236 ALX04_RS03840 b67155210a673ee9fdc5d80226308365 492 SUPERFAMILY SSF52096 216 393 1.03E-68 T 28-03-2018 IPR029045 ClpP/crotonase-like domain ALX04_RS03840 b67155210a673ee9fdc5d80226308365 492 SUPERFAMILY SSF52096 62 142 1.03E-68 T 28-03-2018 IPR029045 ClpP/crotonase-like domain ALX04_RS12040 fb69ebdda3f6f61410a9ea915d664912 274 Gene3D G3DSA:3.40.1190.20 1 271 3.8E-60 T 28-03-2018 IPR029056 Ribokinase-like ALX04_RS12040 fb69ebdda3f6f61410a9ea915d664912 274 SUPERFAMILY SSF53613 3 263 2.49E-77 T 28-03-2018 IPR029056 Ribokinase-like ALX04_RS12040 fb69ebdda3f6f61410a9ea915d664912 274 Pfam PF08543 Phosphomethylpyrimidine kinase 14 260 3.0E-87 T 28-03-2018 IPR013749 Pyridoxamine kinase/Phosphomethylpyrimidine kinase Reactome: R-HSA-6798695|Reactome: R-HSA-964975 ALX04_RS12040 fb69ebdda3f6f61410a9ea915d664912 274 TIGRFAM TIGR00097 HMP-P_kinase: hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 7 262 1.1E-96 T 28-03-2018 IPR004399 Hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase GO:0008972|GO:0009228 KEGG: 00730+2.7.1.49|MetaCyc: PWY-6910|MetaCyc: PWY-7356|MetaCyc: PWY-7357 ALX04_RS02000 26a234f591962009b2c41eeb06f393c3 373 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 219 232 - T 28-03-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 ALX04_RS02000 26a234f591962009b2c41eeb06f393c3 373 Pfam PF00155 Aminotransferase class I and II 53 361 1.8E-39 T 28-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 ALX04_RS02000 26a234f591962009b2c41eeb06f393c3 373 Gene3D G3DSA:3.40.640.10 58 258 4.3E-43 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 ALX04_RS02000 26a234f591962009b2c41eeb06f393c3 373 SUPERFAMILY SSF53383 43 371 1.09E-74 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase ALX04_RS02000 26a234f591962009b2c41eeb06f393c3 373 Gene3D G3DSA:3.90.1150.10 259 373 1.1E-18 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 ALX04_RS07885 d7752ed3bb64593199244ecc95936572 413 ProSitePatterns PS00184 Phosphoribosylglycinamide synthetase signature. 283 290 - T 28-03-2018 IPR020559 Phosphoribosylglycinamide synthetase, conserved site GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 ALX04_RS07885 d7752ed3bb64593199244ecc95936572 413 Pfam PF02844 Phosphoribosylglycinamide synthetase, N domain 3 102 2.5E-32 T 28-03-2018 IPR020562 Phosphoribosylglycinamide synthetase, N-terminal GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 ALX04_RS07885 d7752ed3bb64593199244ecc95936572 413 SMART SM01210 322 408 1.4E-21 T 28-03-2018 IPR020560 Phosphoribosylglycinamide synthetase, C-domain GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 ALX04_RS07885 d7752ed3bb64593199244ecc95936572 413 SUPERFAMILY SSF56059 104 312 1.03E-51 T 28-03-2018 ALX04_RS07885 d7752ed3bb64593199244ecc95936572 413 SUPERFAMILY SSF52440 2 103 6.19E-33 T 28-03-2018 IPR016185 Pre-ATP-grasp domain ALX04_RS07885 d7752ed3bb64593199244ecc95936572 413 SMART SM01209 103 289 6.0E-103 T 28-03-2018 ALX04_RS07885 d7752ed3bb64593199244ecc95936572 413 Gene3D G3DSA:3.90.600.10 322 408 1.2E-16 T 28-03-2018 IPR020560 Phosphoribosylglycinamide synthetase, C-domain GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 ALX04_RS07885 d7752ed3bb64593199244ecc95936572 413 Gene3D G3DSA:3.30.470.20 185 321 5.0E-49 T 28-03-2018 ALX04_RS07885 d7752ed3bb64593199244ecc95936572 413 Gene3D G3DSA:3.40.50.20 3 86 5.1E-33 T 28-03-2018 ALX04_RS07885 d7752ed3bb64593199244ecc95936572 413 Hamap MF_00138 Phosphoribosylamine--glycine ligase [purD]. 2 408 37.722 T 28-03-2018 IPR000115 Phosphoribosylglycinamide synthetase GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 ALX04_RS07885 d7752ed3bb64593199244ecc95936572 413 TIGRFAM TIGR00877 purD: phosphoribosylamine--glycine ligase 3 407 3.3E-129 T 28-03-2018 IPR000115 Phosphoribosylglycinamide synthetase GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 ALX04_RS07885 d7752ed3bb64593199244ecc95936572 413 Gene3D G3DSA:3.30.1490.20 87 183 6.3E-20 T 28-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 ALX04_RS07885 d7752ed3bb64593199244ecc95936572 413 SUPERFAMILY SSF51246 322 407 7.3E-18 T 28-03-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 ALX04_RS07885 d7752ed3bb64593199244ecc95936572 413 Pfam PF02843 Phosphoribosylglycinamide synthetase, C domain 324 405 1.5E-17 T 28-03-2018 IPR020560 Phosphoribosylglycinamide synthetase, C-domain GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 ALX04_RS07885 d7752ed3bb64593199244ecc95936572 413 Pfam PF01071 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain 103 289 4.9E-61 T 28-03-2018 IPR020561 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 ALX04_RS13940 bab2e8c7b94045b2612f565b3dbcf7ef 228 Gene3D G3DSA:3.30.310.20 135 224 0.036 T 28-03-2018 IPR010316 DNA-3-methyladenine glycosylase AlkA, N-terminal ALX04_RS13940 bab2e8c7b94045b2612f565b3dbcf7ef 228 Pfam PF09669 Phage regulatory protein Rha (Phage_pRha) 20 103 6.3E-11 T 28-03-2018 IPR014054 Bacteriophage regulatory protein, Rha family ALX04_RS14300 3cfc80f9f8884d2c87124d572592df8e 229 ProSitePatterns PS01199 Ribosomal protein L1 signature. 121 139 - T 28-03-2018 IPR023673 Ribosomal protein L1, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 ALX04_RS14300 3cfc80f9f8884d2c87124d572592df8e 229 SUPERFAMILY SSF56808 6 225 3.14E-82 T 28-03-2018 IPR023674 Ribosomal protein L1-like ALX04_RS14300 3cfc80f9f8884d2c87124d572592df8e 229 TIGRFAM TIGR01169 rplA_bact: ribosomal protein uL1 3 227 1.2E-100 T 28-03-2018 IPR005878 Ribosomal protein L1, bacterial-type GO:0003723|GO:0003735|GO:0006412|GO:0015934 ALX04_RS14300 3cfc80f9f8884d2c87124d572592df8e 229 Hamap MF_01318_B 50S ribosomal protein L1 [rplA]. 2 229 42.758 T 28-03-2018 IPR005878 Ribosomal protein L1, bacterial-type GO:0003723|GO:0003735|GO:0006412|GO:0015934 ALX04_RS14300 3cfc80f9f8884d2c87124d572592df8e 229 Gene3D G3DSA:3.40.50.790 68 148 8.4E-38 T 28-03-2018 IPR016095 Ribosomal protein L1, 3-layer alpha/beta-sandwich ALX04_RS14300 3cfc80f9f8884d2c87124d572592df8e 229 Pfam PF00687 Ribosomal protein L1p/L10e family 31 220 3.8E-52 T 28-03-2018 IPR028364 Ribosomal protein L1/ribosomal biogenesis protein ALX04_RS14300 3cfc80f9f8884d2c87124d572592df8e 229 PIRSF PIRSF002155 1 227 2.8E-79 T 28-03-2018 IPR002143 Ribosomal protein L1 GO:0003723|GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 ALX04_RS14300 3cfc80f9f8884d2c87124d572592df8e 229 Gene3D G3DSA:3.30.190.20 149 228 1.8E-16 T 28-03-2018 ALX04_RS08205 a61b7b3ba32912a243c13bd20f3b3c9b 316 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 19 196 3.8E-9 T 28-03-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0008152|GO:0016616|GO:0051287|GO:0055114 ALX04_RS08205 a61b7b3ba32912a243c13bd20f3b3c9b 316 SUPERFAMILY SSF52283 3 115 4.25E-17 T 28-03-2018 ALX04_RS08205 a61b7b3ba32912a243c13bd20f3b3c9b 316 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 103 278 3.6E-48 T 28-03-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 ALX04_RS08205 a61b7b3ba32912a243c13bd20f3b3c9b 316 SUPERFAMILY SSF51735 95 279 6.22E-46 T 28-03-2018 IPR016040 NAD(P)-binding domain ALX04_RS08205 a61b7b3ba32912a243c13bd20f3b3c9b 316 Gene3D G3DSA:3.40.50.720 109 279 1.1E-46 T 28-03-2018 ALX04_RS08205 a61b7b3ba32912a243c13bd20f3b3c9b 316 Gene3D G3DSA:3.40.50.720 1 108 4.4E-19 T 28-03-2018 ALX04_RS14285 20e810a893377695b52ce1c9d9d1b07d 182 TIGRFAM TIGR00922 nusG: transcription termination/antitermination factor NusG 9 181 5.4E-61 T 28-03-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 ALX04_RS14285 20e810a893377695b52ce1c9d9d1b07d 182 Pfam PF02357 Transcription termination factor nusG 7 114 6.1E-28 T 28-03-2018 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 ALX04_RS14285 20e810a893377695b52ce1c9d9d1b07d 182 Gene3D G3DSA:3.30.70.940 6 120 1.8E-42 T 28-03-2018 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 ALX04_RS14285 20e810a893377695b52ce1c9d9d1b07d 182 SMART SM00739 127 154 2.3E-5 T 28-03-2018 IPR005824 KOW ALX04_RS14285 20e810a893377695b52ce1c9d9d1b07d 182 SMART SM00738 6 117 2.5E-47 T 28-03-2018 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 ALX04_RS14285 20e810a893377695b52ce1c9d9d1b07d 182 Hamap MF_00948 Transcription termination/antitermination protein NusG [nusG]. 6 181 27.169 T 28-03-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 ALX04_RS14285 20e810a893377695b52ce1c9d9d1b07d 182 PRINTS PR00338 Transcription termination factor NUSG signature 157 173 7.3E-15 T 28-03-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 ALX04_RS14285 20e810a893377695b52ce1c9d9d1b07d 182 PRINTS PR00338 Transcription termination factor NUSG signature 61 73 7.3E-15 T 28-03-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 ALX04_RS14285 20e810a893377695b52ce1c9d9d1b07d 182 PRINTS PR00338 Transcription termination factor NUSG signature 139 154 7.3E-15 T 28-03-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 ALX04_RS14285 20e810a893377695b52ce1c9d9d1b07d 182 SUPERFAMILY SSF82679 6 117 4.05E-38 T 28-03-2018 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 ALX04_RS14285 20e810a893377695b52ce1c9d9d1b07d 182 SUPERFAMILY SSF50104 125 181 1.59E-16 T 28-03-2018 IPR008991 Translation protein SH3-like domain ALX04_RS14285 20e810a893377695b52ce1c9d9d1b07d 182 Gene3D G3DSA:2.30.30.30 122 181 2.0E-20 T 28-03-2018 IPR014722 Ribosomal protein L2 domain 2 ALX04_RS13030 2b712f6f802ad54fce3c303e2e7892ec 300 Pfam PF01145 SPFH domain / Band 7 family 25 192 7.3E-29 T 28-03-2018 IPR001107 Band 7 domain ALX04_RS13030 2b712f6f802ad54fce3c303e2e7892ec 300 SMART SM00244 20 177 3.2E-27 T 28-03-2018 IPR001107 Band 7 domain ALX04_RS13030 2b712f6f802ad54fce3c303e2e7892ec 300 SUPERFAMILY SSF117892 52 184 1.15E-27 T 28-03-2018 IPR001107 Band 7 domain ALX04_RS13030 2b712f6f802ad54fce3c303e2e7892ec 300 PRINTS PR00721 Stomatin signature 74 95 1.3E-11 T 28-03-2018 IPR001972 Stomatin family GO:0016020 ALX04_RS13030 2b712f6f802ad54fce3c303e2e7892ec 300 PRINTS PR00721 Stomatin signature 109 126 1.3E-11 T 28-03-2018 IPR001972 Stomatin family GO:0016020 ALX04_RS13030 2b712f6f802ad54fce3c303e2e7892ec 300 PRINTS PR00721 Stomatin signature 129 152 1.3E-11 T 28-03-2018 IPR001972 Stomatin family GO:0016020 ALX04_RS13030 2b712f6f802ad54fce3c303e2e7892ec 300 PRINTS PR00721 Stomatin signature 172 193 1.3E-11 T 28-03-2018 IPR001972 Stomatin family GO:0016020 ALX04_RS13030 2b712f6f802ad54fce3c303e2e7892ec 300 PRINTS PR00721 Stomatin signature 153 171 1.3E-11 T 28-03-2018 IPR001972 Stomatin family GO:0016020 ALX04_RS11570 03210bc50589f146b7f510e267f95fc2 455 Hamap MF_00377 Chromosomal replication initiator protein DnaA [dnaA]. 5 454 32.264 T 28-03-2018 IPR001957 Chromosomal replication control, initiator DnaA GO:0003677|GO:0003688|GO:0005524|GO:0006270|GO:0006275 ALX04_RS11570 03210bc50589f146b7f510e267f95fc2 455 Pfam PF11638 DnaA N-terminal domain 6 61 8.1E-6 T 28-03-2018 IPR024633 DnaA N-terminal domain ALX04_RS11570 03210bc50589f146b7f510e267f95fc2 455 Gene3D G3DSA:1.10.1750.10 357 454 4.3E-34 T 28-03-2018 IPR013159 Chromosomal replication initiator, DnaA C-terminal GO:0005524|GO:0006270|GO:0006275|GO:0043565 ALX04_RS11570 03210bc50589f146b7f510e267f95fc2 455 SUPERFAMILY SSF48295 352 455 1.49E-34 T 28-03-2018 IPR010921 Trp repressor/replication initiator GO:0043565 ALX04_RS11570 03210bc50589f146b7f510e267f95fc2 455 TIGRFAM TIGR00362 DnaA: chromosomal replication initiator protein DnaA 8 452 4.6E-173 T 28-03-2018 IPR001957 Chromosomal replication control, initiator DnaA GO:0003677|GO:0003688|GO:0005524|GO:0006270|GO:0006275 ALX04_RS11570 03210bc50589f146b7f510e267f95fc2 455 Gene3D G3DSA:3.40.50.300 116 283 3.5E-22 T 28-03-2018 ALX04_RS11570 03210bc50589f146b7f510e267f95fc2 455 SUPERFAMILY SSF52540 118 330 5.43E-46 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase ALX04_RS11570 03210bc50589f146b7f510e267f95fc2 455 Gene3D G3DSA:1.10.8.60 285 355 3.2E-27 T 28-03-2018 ALX04_RS11570 03210bc50589f146b7f510e267f95fc2 455 SMART SM00382 151 282 3.1E-7 T 28-03-2018 IPR003593 AAA+ ATPase domain ALX04_RS11570 03210bc50589f146b7f510e267f95fc2 455 ProSitePatterns PS01008 DnaA protein signature. 413 432 - T 28-03-2018 IPR018312 Chromosomal replication control, initiator DnaA, conserved site GO:0003677|GO:0003688|GO:0005524|GO:0006270|GO:0006275 ALX04_RS11570 03210bc50589f146b7f510e267f95fc2 455 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 184 198 1.9E-50 T 28-03-2018 IPR020591 Chromosomal replication control, initiator DnaA-like ALX04_RS11570 03210bc50589f146b7f510e267f95fc2 455 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 250 277 1.9E-50 T 28-03-2018 IPR020591 Chromosomal replication control, initiator DnaA-like ALX04_RS11570 03210bc50589f146b7f510e267f95fc2 455 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 152 172 1.9E-50 T 28-03-2018 IPR020591 Chromosomal replication control, initiator DnaA-like ALX04_RS11570 03210bc50589f146b7f510e267f95fc2 455 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 413 432 1.9E-50 T 28-03-2018 IPR020591 Chromosomal replication control, initiator DnaA-like ALX04_RS11570 03210bc50589f146b7f510e267f95fc2 455 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 216 230 1.9E-50 T 28-03-2018 IPR020591 Chromosomal replication control, initiator DnaA-like ALX04_RS11570 03210bc50589f146b7f510e267f95fc2 455 SMART SM00760 363 432 5.5E-41 T 28-03-2018 IPR013159 Chromosomal replication initiator, DnaA C-terminal GO:0005524|GO:0006270|GO:0006275|GO:0043565 ALX04_RS11570 03210bc50589f146b7f510e267f95fc2 455 Pfam PF00308 Bacterial dnaA protein 119 336 9.4E-97 T 28-03-2018 IPR013317 Chromosomal replication initiator protein DnaA ALX04_RS11570 03210bc50589f146b7f510e267f95fc2 455 Pfam PF08299 Bacterial dnaA protein helix-turn-helix 366 432 8.6E-32 T 28-03-2018 IPR013159 Chromosomal replication initiator, DnaA C-terminal GO:0005524|GO:0006270|GO:0006275|GO:0043565 ALX04_RS05615 1a6bae607eb77cb2c740293a97114efd 119 Gene3D G3DSA:2.40.33.40 1 117 6.7E-33 T 28-03-2018 IPR004716 Phosphotransferase system, glucitol/sorbitol-specific IIA component GO:0005737|GO:0008982|GO:0009401 KEGG: 00051+2.7.1.198|KEGG: 00710+2.7.1.19|MetaCyc: PWY-5723 ALX04_RS05615 1a6bae607eb77cb2c740293a97114efd 119 Pfam PF03829 PTS system glucitol/sorbitol-specific IIA component 4 115 3.9E-29 T 28-03-2018 IPR004716 Phosphotransferase system, glucitol/sorbitol-specific IIA component GO:0005737|GO:0008982|GO:0009401 KEGG: 00051+2.7.1.198|KEGG: 00710+2.7.1.19|MetaCyc: PWY-5723 ALX04_RS05615 1a6bae607eb77cb2c740293a97114efd 119 SUPERFAMILY SSF141530 1 117 1.7E-31 T 28-03-2018 IPR004716 Phosphotransferase system, glucitol/sorbitol-specific IIA component GO:0005737|GO:0008982|GO:0009401 KEGG: 00051+2.7.1.198|KEGG: 00710+2.7.1.19|MetaCyc: PWY-5723 ALX04_RS05615 1a6bae607eb77cb2c740293a97114efd 119 ProDom PD015842 PTS IIA COMPONENT GLUCITOL/SORBITOL-SPECIFIC SYSTEM ENZYME TRANSFERASE SYSTEM PHOSPHOTRANSFERASE EIIA 18 117 2.0E-51 T 28-03-2018 IPR004716 Phosphotransferase system, glucitol/sorbitol-specific IIA component GO:0005737|GO:0008982|GO:0009401 KEGG: 00051+2.7.1.198|KEGG: 00710+2.7.1.19|MetaCyc: PWY-5723 ALX04_RS14795 417b93b1763cd3e4d173d174047e0c52 804 SUPERFAMILY SSF50249 216 633 1.77E-143 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold ALX04_RS14795 417b93b1763cd3e4d173d174047e0c52 804 TIGRFAM TIGR00358 3_prime_RNase: VacB and RNase II family 3'-5' exoribonucleases 63 715 3.6E-201 T 28-03-2018 IPR004476 Ribonuclease II/ribonuclease R GO:0003723|GO:0004540|GO:0016070 ALX04_RS14795 417b93b1763cd3e4d173d174047e0c52 804 Pfam PF00773 RNB domain 256 584 4.1E-111 T 28-03-2018 ALX04_RS14795 417b93b1763cd3e4d173d174047e0c52 804 TIGRFAM TIGR02063 RNase_R: ribonuclease R 5 715 8.0E-258 T 28-03-2018 IPR011805 Ribonuclease R GO:0003723|GO:0004518 ALX04_RS14795 417b93b1763cd3e4d173d174047e0c52 804 SUPERFAMILY SSF50249 634 716 4.19E-21 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold ALX04_RS14795 417b93b1763cd3e4d173d174047e0c52 804 SUPERFAMILY SSF50249 58 137 1.65E-13 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold ALX04_RS14795 417b93b1763cd3e4d173d174047e0c52 804 ProSitePatterns PS01175 Ribonuclease II family signature. 553 577 - T 28-03-2018 IPR022966 Ribonuclease II/R, conserved site ALX04_RS14795 417b93b1763cd3e4d173d174047e0c52 804 SMART SM00955 256 586 4.5E-180 T 28-03-2018 ALX04_RS14795 417b93b1763cd3e4d173d174047e0c52 804 Pfam PF08206 Ribonuclease B OB domain 74 130 1.9E-12 T 28-03-2018 IPR013223 Ribonuclease B, N-terminal OB domain ALX04_RS14795 417b93b1763cd3e4d173d174047e0c52 804 Pfam PF00575 S1 RNA binding domain 633 712 8.0E-16 T 28-03-2018 IPR003029 S1 domain GO:0003676 ALX04_RS14795 417b93b1763cd3e4d173d174047e0c52 804 Hamap MF_01895 Ribonuclease R [rnr]. 25 715 54.022 T 28-03-2018 IPR011805 Ribonuclease R GO:0003723|GO:0004518 ALX04_RS14795 417b93b1763cd3e4d173d174047e0c52 804 SUPERFAMILY SSF50249 128 231 1.88E-5 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold ALX04_RS14795 417b93b1763cd3e4d173d174047e0c52 804 SMART SM00316 633 715 7.0E-17 T 28-03-2018 IPR022967 RNA-binding domain, S1 ALX04_RS14795 417b93b1763cd3e4d173d174047e0c52 804 Gene3D G3DSA:2.40.50.140 632 716 3.7E-23 T 28-03-2018 ALX04_RS00375 5cf356353558f5c7424d1c8c95c7ec97 102 PRINTS PR00971 Ribosomal protein S10 family signature 61 75 9.6E-22 T 28-03-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 ALX04_RS00375 5cf356353558f5c7424d1c8c95c7ec97 102 PRINTS PR00971 Ribosomal protein S10 family signature 40 55 9.6E-22 T 28-03-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 ALX04_RS00375 5cf356353558f5c7424d1c8c95c7ec97 102 PRINTS PR00971 Ribosomal protein S10 family signature 5 18 9.6E-22 T 28-03-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 ALX04_RS00375 5cf356353558f5c7424d1c8c95c7ec97 102 ProSitePatterns PS00361 Ribosomal protein S10 signature. 29 44 - T 28-03-2018 IPR018268 Ribosomal protein S10, conserved site GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 ALX04_RS00375 5cf356353558f5c7424d1c8c95c7ec97 102 Hamap MF_00508 30S ribosomal protein S10 [rpsJ]. 3 102 28.728 T 28-03-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 ALX04_RS00375 5cf356353558f5c7424d1c8c95c7ec97 102 SMART SM01403 7 101 2.7E-61 T 28-03-2018 IPR027486 Ribosomal protein S10 domain ALX04_RS00375 5cf356353558f5c7424d1c8c95c7ec97 102 Pfam PF00338 Ribosomal protein S10p/S20e 7 101 8.6E-38 T 28-03-2018 IPR027486 Ribosomal protein S10 domain ALX04_RS00375 5cf356353558f5c7424d1c8c95c7ec97 102 TIGRFAM TIGR01049 rpsJ_bact: ribosomal protein uS10 4 101 2.8E-48 T 28-03-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 ALX04_RS00375 5cf356353558f5c7424d1c8c95c7ec97 102 SUPERFAMILY SSF54999 5 102 1.11E-40 T 28-03-2018 IPR027486 Ribosomal protein S10 domain ALX04_RS00375 5cf356353558f5c7424d1c8c95c7ec97 102 Gene3D G3DSA:3.30.70.600 3 102 1.6E-38 T 28-03-2018 IPR027486 Ribosomal protein S10 domain ALX04_RS04060 a808e46b64c055c4d869e0a28cfd217a 177 SUPERFAMILY SSF46785 28 164 7.86E-26 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS04060 a808e46b64c055c4d869e0a28cfd217a 177 SMART SM00347 50 152 5.2E-16 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 ALX04_RS04060 a808e46b64c055c4d869e0a28cfd217a 177 Pfam PF01047 MarR family 57 117 5.6E-11 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 ALX04_RS04060 a808e46b64c055c4d869e0a28cfd217a 177 Gene3D G3DSA:1.10.10.10 5 173 7.8E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS04060 a808e46b64c055c4d869e0a28cfd217a 177 PRINTS PR00598 Bacterial regulatory protein MarR family signature 93 108 7.0E-13 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 ALX04_RS04060 a808e46b64c055c4d869e0a28cfd217a 177 PRINTS PR00598 Bacterial regulatory protein MarR family signature 112 128 7.0E-13 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 ALX04_RS04060 a808e46b64c055c4d869e0a28cfd217a 177 PRINTS PR00598 Bacterial regulatory protein MarR family signature 76 92 7.0E-13 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 ALX04_RS04060 a808e46b64c055c4d869e0a28cfd217a 177 PRINTS PR00598 Bacterial regulatory protein MarR family signature 142 162 7.0E-13 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 ALX04_RS11205 00c8d4fdd2c5e9cf392e3b4ad0f7be3b 766 ProSitePatterns PS00129 Glycosyl hydrolases family 31 active site. 403 410 - T 28-03-2018 IPR030458 Glycosyl hydrolases family 31, active site ALX04_RS11205 00c8d4fdd2c5e9cf392e3b4ad0f7be3b 766 Gene3D G3DSA:3.20.20.80 237 606 5.4E-152 T 28-03-2018 ALX04_RS11205 00c8d4fdd2c5e9cf392e3b4ad0f7be3b 766 SUPERFAMILY SSF51445 239 585 3.62E-98 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily ALX04_RS11205 00c8d4fdd2c5e9cf392e3b4ad0f7be3b 766 Pfam PF13802 Galactose mutarotase-like 143 210 6.6E-18 T 28-03-2018 IPR025887 Glycoside hydrolase family 31, N-terminal domain ALX04_RS11205 00c8d4fdd2c5e9cf392e3b4ad0f7be3b 766 Pfam PF01055 Glycosyl hydrolases family 31 231 671 5.2E-155 T 28-03-2018 IPR000322 Glycoside hydrolase family 31 GO:0004553|GO:0005975 ALX04_RS11205 00c8d4fdd2c5e9cf392e3b4ad0f7be3b 766 Gene3D G3DSA:2.60.40.1180 607 667 2.8E-25 T 28-03-2018 ALX04_RS11205 00c8d4fdd2c5e9cf392e3b4ad0f7be3b 766 Gene3D G3DSA:2.60.40.1180 669 764 2.7E-8 T 28-03-2018 ALX04_RS11205 00c8d4fdd2c5e9cf392e3b4ad0f7be3b 766 SUPERFAMILY SSF74650 8 237 3.45E-42 T 28-03-2018 IPR011013 Galactose mutarotase-like domain GO:0003824|GO:0005975|GO:0030246 ALX04_RS11205 00c8d4fdd2c5e9cf392e3b4ad0f7be3b 766 Pfam PF16338 Domain of unknown function (DUF4968) 9 97 3.0E-17 T 28-03-2018 IPR032513 Alpha-glucosidase, domain of unknown function DUF4968 ALX04_RS11205 00c8d4fdd2c5e9cf392e3b4ad0f7be3b 766 Gene3D G3DSA:2.60.40.1760 3 236 6.2E-40 T 28-03-2018 ALX04_RS11205 00c8d4fdd2c5e9cf392e3b4ad0f7be3b 766 SUPERFAMILY SSF51011 587 666 1.01E-22 T 28-03-2018 ALX04_RS11205 00c8d4fdd2c5e9cf392e3b4ad0f7be3b 766 Pfam PF17137 Domain of unknown function (DUF5110) 688 748 8.4E-9 T 28-03-2018 IPR033403 Domain of unknown function DUF5110 ALX04_RS03020 70904c6c544724880234ceaf065ebc7e 147 SUPERFAMILY SSF54637 7 143 4.02E-43 T 28-03-2018 IPR029069 HotDog domain ALX04_RS03020 70904c6c544724880234ceaf065ebc7e 147 TIGRFAM TIGR01750 fabZ: beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ 5 140 1.2E-51 T 28-03-2018 IPR010084 Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ GO:0005737|GO:0006633|GO:0016836 KEGG: 00061+4.2.1.59|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 ALX04_RS03020 70904c6c544724880234ceaf065ebc7e 147 Hamap MF_00406 3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ [fabZ]. 4 143 32.654 T 28-03-2018 IPR010084 Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ GO:0005737|GO:0006633|GO:0016836 KEGG: 00061+4.2.1.59|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 ALX04_RS03020 70904c6c544724880234ceaf065ebc7e 147 Pfam PF07977 FabA-like domain 13 134 8.3E-33 T 28-03-2018 IPR013114 Beta-hydroxydecanoyl thiol ester dehydrase, FabA/FabZ KEGG: 00061+4.2.1.59|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 ALX04_RS03020 70904c6c544724880234ceaf065ebc7e 147 Gene3D G3DSA:3.10.129.10 1 143 2.8E-49 T 28-03-2018 ALX04_RS06570 b37c849aa90f490fe877e5b93e627909 371 SUPERFAMILY SSF54106 326 370 3.92E-10 T 28-03-2018 IPR018392 LysM domain ALX04_RS06570 b37c849aa90f490fe877e5b93e627909 371 Gene3D G3DSA:3.20.20.80 6 236 7.1E-30 T 28-03-2018 ALX04_RS06570 b37c849aa90f490fe877e5b93e627909 371 Gene3D G3DSA:2.30.30.410 237 321 1.6E-12 T 28-03-2018 ALX04_RS06570 b37c849aa90f490fe877e5b93e627909 371 SMART SM00287 249 316 2.4E-11 T 28-03-2018 IPR003646 SH3-like domain, bacterial-type ALX04_RS06570 b37c849aa90f490fe877e5b93e627909 371 Gene3D G3DSA:3.10.350.10 324 371 1.4E-12 T 28-03-2018 ALX04_RS06570 b37c849aa90f490fe877e5b93e627909 371 Pfam PF01476 LysM domain 328 370 1.5E-11 T 28-03-2018 IPR018392 LysM domain ALX04_RS06570 b37c849aa90f490fe877e5b93e627909 371 Pfam PF08460 Bacterial SH3 domain 249 303 1.3E-5 T 28-03-2018 IPR003646 SH3-like domain, bacterial-type ALX04_RS06570 b37c849aa90f490fe877e5b93e627909 371 SMART SM00257 327 371 7.2E-13 T 28-03-2018 IPR018392 LysM domain ALX04_RS06570 b37c849aa90f490fe877e5b93e627909 371 SUPERFAMILY SSF51445 15 210 6.81E-27 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily ALX04_RS06570 b37c849aa90f490fe877e5b93e627909 371 Pfam PF01183 Glycosyl hydrolases family 25 18 192 4.0E-25 T 28-03-2018 IPR002053 Glycoside hydrolase, family 25 GO:0003796|GO:0009253|GO:0016998 ALX04_RS11000 66caa7993e6dd048f8ee58642fb75026 335 Gene3D G3DSA:3.40.50.2300 165 335 4.0E-36 T 28-03-2018 ALX04_RS11000 66caa7993e6dd048f8ee58642fb75026 335 Pfam PF00356 Bacterial regulatory proteins, lacI family 6 51 1.6E-15 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 ALX04_RS11000 66caa7993e6dd048f8ee58642fb75026 335 Gene3D G3DSA:3.40.50.2300 60 164 4.9E-5 T 28-03-2018 ALX04_RS11000 66caa7993e6dd048f8ee58642fb75026 335 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 6 16 1.7E-5 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 ALX04_RS11000 66caa7993e6dd048f8ee58642fb75026 335 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 16 26 1.7E-5 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 ALX04_RS11000 66caa7993e6dd048f8ee58642fb75026 335 Gene3D G3DSA:1.10.260.40 3 59 2.2E-14 T 28-03-2018 ALX04_RS11000 66caa7993e6dd048f8ee58642fb75026 335 SMART SM00354 4 75 1.1E-7 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 ALX04_RS11000 66caa7993e6dd048f8ee58642fb75026 335 SUPERFAMILY SSF47413 5 52 3.94E-11 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 ALX04_RS11000 66caa7993e6dd048f8ee58642fb75026 335 ProSitePatterns PS00356 LacI-type HTH domain signature. 7 25 - T 28-03-2018 ALX04_RS11000 66caa7993e6dd048f8ee58642fb75026 335 SUPERFAMILY SSF53822 67 328 6.09E-46 T 28-03-2018 IPR028082 Periplasmic binding protein-like I ALX04_RS11000 66caa7993e6dd048f8ee58642fb75026 335 Pfam PF13377 Periplasmic binding protein-like domain 167 334 8.3E-38 T 28-03-2018 ALX04_RS00290 6accd1c5006baa362b902b7ec14eebd7 425 TIGRFAM TIGR00414 serS: serine--tRNA ligase 1 415 2.3E-166 T 28-03-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 ALX04_RS00290 6accd1c5006baa362b902b7ec14eebd7 425 PRINTS PR00981 Seryl-tRNA synthetase signature 263 275 2.1E-30 T 28-03-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 ALX04_RS00290 6accd1c5006baa362b902b7ec14eebd7 425 PRINTS PR00981 Seryl-tRNA synthetase signature 275 288 2.1E-30 T 28-03-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 ALX04_RS00290 6accd1c5006baa362b902b7ec14eebd7 425 PRINTS PR00981 Seryl-tRNA synthetase signature 332 348 2.1E-30 T 28-03-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 ALX04_RS00290 6accd1c5006baa362b902b7ec14eebd7 425 PRINTS PR00981 Seryl-tRNA synthetase signature 315 328 2.1E-30 T 28-03-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 ALX04_RS00290 6accd1c5006baa362b902b7ec14eebd7 425 PRINTS PR00981 Seryl-tRNA synthetase signature 350 366 2.1E-30 T 28-03-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 ALX04_RS00290 6accd1c5006baa362b902b7ec14eebd7 425 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 223 398 9.4E-39 T 28-03-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 ALX04_RS00290 6accd1c5006baa362b902b7ec14eebd7 425 Gene3D G3DSA:1.10.287.40 2 105 2.1E-25 T 28-03-2018 ALX04_RS00290 6accd1c5006baa362b902b7ec14eebd7 425 PIRSF PIRSF001529 1 424 9.8E-177 T 28-03-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 ALX04_RS00290 6accd1c5006baa362b902b7ec14eebd7 425 Gene3D G3DSA:3.30.930.10 106 425 2.8E-97 T 28-03-2018 ALX04_RS00290 6accd1c5006baa362b902b7ec14eebd7 425 Hamap MF_00176 Serine--tRNA ligase [serS]. 1 420 41.352 T 28-03-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 ALX04_RS00290 6accd1c5006baa362b902b7ec14eebd7 425 SUPERFAMILY SSF46589 1 113 1.2E-30 T 28-03-2018 IPR010978 tRNA-binding arm GO:0000166 ALX04_RS00290 6accd1c5006baa362b902b7ec14eebd7 425 SUPERFAMILY SSF55681 118 416 8.87E-103 T 28-03-2018 ALX04_RS00290 6accd1c5006baa362b902b7ec14eebd7 425 Pfam PF02403 Seryl-tRNA synthetase N-terminal domain 1 108 1.1E-33 T 28-03-2018 IPR015866 Serine-tRNA synthetase, type1, N-terminal KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281|Reactome: R-HSA-2408557|Reactome: R-HSA-379716 ALX04_RS10655 416ec1ddefc8a5b9877699a6ccae3482 870 SUPERFAMILY SSF56784 318 338 1.37E-61 T 28-03-2018 IPR023214 HAD-like domain ALX04_RS10655 416ec1ddefc8a5b9877699a6ccae3482 870 SUPERFAMILY SSF56784 459 702 1.37E-61 T 28-03-2018 IPR023214 HAD-like domain ALX04_RS10655 416ec1ddefc8a5b9877699a6ccae3482 870 Pfam PF00690 Cation transporter/ATPase, N-terminus 9 64 2.6E-11 T 28-03-2018 IPR004014 Cation-transporting P-type ATPase, N-terminal Reactome: R-HSA-936837 ALX04_RS10655 416ec1ddefc8a5b9877699a6ccae3482 870 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 455 473 1.8E-15 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 ALX04_RS10655 416ec1ddefc8a5b9877699a6ccae3482 870 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 631 656 1.8E-15 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 ALX04_RS10655 416ec1ddefc8a5b9877699a6ccae3482 870 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 571 587 1.8E-15 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 ALX04_RS10655 416ec1ddefc8a5b9877699a6ccae3482 870 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 599 615 1.8E-15 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 ALX04_RS10655 416ec1ddefc8a5b9877699a6ccae3482 870 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 497 508 3.5E-40 T 28-03-2018 ALX04_RS10655 416ec1ddefc8a5b9877699a6ccae3482 870 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 599 618 3.5E-40 T 28-03-2018 ALX04_RS10655 416ec1ddefc8a5b9877699a6ccae3482 870 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 320 334 3.5E-40 T 28-03-2018 ALX04_RS10655 416ec1ddefc8a5b9877699a6ccae3482 870 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 160 174 3.5E-40 T 28-03-2018 ALX04_RS10655 416ec1ddefc8a5b9877699a6ccae3482 870 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 519 529 3.5E-40 T 28-03-2018 ALX04_RS10655 416ec1ddefc8a5b9877699a6ccae3482 870 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 623 635 3.5E-40 T 28-03-2018 ALX04_RS10655 416ec1ddefc8a5b9877699a6ccae3482 870 SUPERFAMILY SSF81660 326 509 6.05E-39 T 28-03-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 ALX04_RS10655 416ec1ddefc8a5b9877699a6ccae3482 870 SUPERFAMILY SSF81665 649 861 3.01E-94 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 ALX04_RS10655 416ec1ddefc8a5b9877699a6ccae3482 870 SUPERFAMILY SSF81665 220 314 3.01E-94 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 ALX04_RS10655 416ec1ddefc8a5b9877699a6ccae3482 870 SUPERFAMILY SSF81665 9 113 3.01E-94 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 ALX04_RS10655 416ec1ddefc8a5b9877699a6ccae3482 870 Gene3D G3DSA:2.70.150.10 6 220 2.0E-43 T 28-03-2018 ALX04_RS10655 416ec1ddefc8a5b9877699a6ccae3482 870 Gene3D G3DSA:1.20.1110.10 511 858 2.9E-83 T 28-03-2018 ALX04_RS10655 416ec1ddefc8a5b9877699a6ccae3482 870 Pfam PF00122 E1-E2 ATPase 110 299 3.1E-54 T 28-03-2018 ALX04_RS10655 416ec1ddefc8a5b9877699a6ccae3482 870 Pfam PF00702 haloacid dehalogenase-like hydrolase 316 613 1.1E-24 T 28-03-2018 ALX04_RS10655 416ec1ddefc8a5b9877699a6ccae3482 870 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 82 342 4.9E-41 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 ALX04_RS10655 416ec1ddefc8a5b9877699a6ccae3482 870 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 569 685 2.4E-34 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 ALX04_RS10655 416ec1ddefc8a5b9877699a6ccae3482 870 SUPERFAMILY SSF81653 113 218 1.05E-28 T 28-03-2018 IPR008250 P-type ATPase, A domain Reactome: R-HSA-936837 ALX04_RS10655 416ec1ddefc8a5b9877699a6ccae3482 870 SMART SM00831 3 70 2.3E-8 T 28-03-2018 IPR004014 Cation-transporting P-type ATPase, N-terminal Reactome: R-HSA-936837 ALX04_RS10655 416ec1ddefc8a5b9877699a6ccae3482 870 Gene3D G3DSA:3.40.1110.10 283 504 1.0E-33 T 28-03-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 ALX04_RS10655 416ec1ddefc8a5b9877699a6ccae3482 870 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 322 328 - T 28-03-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 ALX04_RS10655 416ec1ddefc8a5b9877699a6ccae3482 870 Pfam PF00689 Cation transporting ATPase, C-terminus 685 855 8.6E-30 T 28-03-2018 IPR006068 Cation-transporting P-type ATPase, C-terminal Reactome: R-HSA-936837 ALX04_RS02440 9651c0db267bb988787bc59dc5c2362f 59 TIGRFAM TIGR01031 rpmF_bact: ribosomal protein bL32 2 56 2.7E-28 T 28-03-2018 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 ALX04_RS02440 9651c0db267bb988787bc59dc5c2362f 59 Hamap MF_00340 50S ribosomal protein L32 [rpmF]. 1 55 21.333 T 28-03-2018 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 ALX04_RS02440 9651c0db267bb988787bc59dc5c2362f 59 SUPERFAMILY SSF57829 1 57 1.53E-23 T 28-03-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 ALX04_RS02440 9651c0db267bb988787bc59dc5c2362f 59 Pfam PF01783 Ribosomal L32p protein family 2 56 4.4E-27 T 28-03-2018 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 ALX04_RS12675 f7fcff9c4dbe312771279c48cf3074b8 263 SUPERFAMILY SSF55920 1 250 7.33E-80 T 28-03-2018 IPR000994 Peptidase M24 ALX04_RS12675 f7fcff9c4dbe312771279c48cf3074b8 263 Gene3D G3DSA:3.90.230.10 1 259 4.5E-75 T 28-03-2018 ALX04_RS12675 f7fcff9c4dbe312771279c48cf3074b8 263 PRINTS PR00599 Methionine aminopeptidase-1 signature 161 173 4.9E-18 T 28-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 ALX04_RS12675 f7fcff9c4dbe312771279c48cf3074b8 263 PRINTS PR00599 Methionine aminopeptidase-1 signature 90 106 4.9E-18 T 28-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 ALX04_RS12675 f7fcff9c4dbe312771279c48cf3074b8 263 PRINTS PR00599 Methionine aminopeptidase-1 signature 192 204 4.9E-18 T 28-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 ALX04_RS12675 f7fcff9c4dbe312771279c48cf3074b8 263 PRINTS PR00599 Methionine aminopeptidase-1 signature 67 80 4.9E-18 T 28-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 ALX04_RS12675 f7fcff9c4dbe312771279c48cf3074b8 263 TIGRFAM TIGR00500 met_pdase_I: methionine aminopeptidase, type I 2 249 1.4E-84 T 28-03-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 ALX04_RS12675 f7fcff9c4dbe312771279c48cf3074b8 263 Pfam PF00557 Metallopeptidase family M24 12 242 8.0E-47 T 28-03-2018 IPR000994 Peptidase M24 ALX04_RS12675 f7fcff9c4dbe312771279c48cf3074b8 263 ProSitePatterns PS00680 Methionine aminopeptidase subfamily 1 signature. 167 185 - T 28-03-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 ALX04_RS12675 f7fcff9c4dbe312771279c48cf3074b8 263 Hamap MF_01974 Methionine aminopeptidase [map]. 2 251 37.938 T 28-03-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 ALX04_RS07680 256f5dc4096d7a404aaaa3fca28b95ec 249 SUPERFAMILY SSF52172 1 133 3.98E-8 T 28-03-2018 IPR011006 CheY-like superfamily ALX04_RS07680 256f5dc4096d7a404aaaa3fca28b95ec 249 SMART SM00850 150 246 1.2E-9 T 28-03-2018 IPR007492 LytTR DNA-binding domain GO:0003677 ALX04_RS07680 256f5dc4096d7a404aaaa3fca28b95ec 249 SMART SM00448 1 122 0.002 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 ALX04_RS07680 256f5dc4096d7a404aaaa3fca28b95ec 249 Pfam PF00072 Response regulator receiver domain 3 110 9.9E-8 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 ALX04_RS07680 256f5dc4096d7a404aaaa3fca28b95ec 249 Gene3D G3DSA:3.40.50.2300 1 140 1.1E-10 T 28-03-2018 ALX04_RS07680 256f5dc4096d7a404aaaa3fca28b95ec 249 Gene3D G3DSA:2.40.50.40 141 212 2.8E-12 T 28-03-2018 ALX04_RS07680 256f5dc4096d7a404aaaa3fca28b95ec 249 Pfam PF04397 LytTr DNA-binding domain 153 244 1.0E-12 T 28-03-2018 IPR007492 LytTR DNA-binding domain GO:0003677 ALX04_RS05435 3ac94b9c222432a27078305a1430c8be 113 Pfam PF08866 Putative amino acid metabolism 1 111 3.3E-44 T 28-03-2018 IPR014965 Putative amino acid metabolism ALX04_RS05435 3ac94b9c222432a27078305a1430c8be 113 Gene3D G3DSA:3.30.1820.10 2 111 3.5E-44 T 28-03-2018 IPR014965 Putative amino acid metabolism ALX04_RS05435 3ac94b9c222432a27078305a1430c8be 113 SUPERFAMILY SSF160800 1 111 3.79E-43 T 28-03-2018 IPR014965 Putative amino acid metabolism ALX04_RS06215 35438b6bb08943a7208a05afe52da95b 405 TIGRFAM TIGR00342 TIGR00342: tRNA sulfurtransferase ThiI 6 372 8.1E-118 T 28-03-2018 IPR003720 tRNA sulfurtransferase ThiI GO:0005737|GO:0016783|GO:0034227 ALX04_RS06215 35438b6bb08943a7208a05afe52da95b 405 Gene3D G3DSA:3.30.2300.10 81 163 4.0E-16 T 28-03-2018 ALX04_RS06215 35438b6bb08943a7208a05afe52da95b 405 Pfam PF02568 Thiamine biosynthesis protein (ThiI) 175 370 1.0E-61 T 28-03-2018 IPR020536 Thil, AANH domain GO:0004810 ALX04_RS06215 35438b6bb08943a7208a05afe52da95b 405 Pfam PF02926 THUMP domain 39 163 2.0E-17 T 28-03-2018 IPR004114 THUMP domain GO:0003723 ALX04_RS06215 35438b6bb08943a7208a05afe52da95b 405 Gene3D G3DSA:3.30.70.1510 5 80 6.1E-25 T 28-03-2018 ALX04_RS06215 35438b6bb08943a7208a05afe52da95b 405 Hamap MF_00021 tRNA sulfurtransferase [thiI]. 1 405 164.841 T 28-03-2018 IPR003720 tRNA sulfurtransferase ThiI GO:0005737|GO:0016783|GO:0034227 ALX04_RS06215 35438b6bb08943a7208a05afe52da95b 405 SUPERFAMILY SSF143437 3 173 9.59E-54 T 28-03-2018 ALX04_RS06215 35438b6bb08943a7208a05afe52da95b 405 SUPERFAMILY SSF52402 174 384 9.54E-48 T 28-03-2018 ALX04_RS06215 35438b6bb08943a7208a05afe52da95b 405 Gene3D G3DSA:3.40.50.620 175 402 1.4E-30 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold ALX04_RS06215 35438b6bb08943a7208a05afe52da95b 405 SMART SM00981 74 165 2.9E-24 T 28-03-2018 IPR004114 THUMP domain GO:0003723 ALX04_RS11660 236a826514755ffa3031d780a7835b8a 390 Gene3D G3DSA:2.160.10.10 276 382 1.4E-10 T 28-03-2018 ALX04_RS11660 236a826514755ffa3031d780a7835b8a 390 SUPERFAMILY SSF53448 19 268 1.97E-33 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases ALX04_RS11660 236a826514755ffa3031d780a7835b8a 390 SUPERFAMILY SSF53448 329 345 1.97E-33 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases ALX04_RS11660 236a826514755ffa3031d780a7835b8a 390 TIGRFAM TIGR02092 glgD: glucose-1-phosphate adenylyltransferase, GlgD subunit 4 380 2.9E-156 T 28-03-2018 IPR011832 Glucose-1-phosphate adenylyltransferase, GlgD subunit GO:0005978 ALX04_RS11660 236a826514755ffa3031d780a7835b8a 390 Pfam PF00483 Nucleotidyl transferase 19 159 1.2E-8 T 28-03-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 ALX04_RS11660 236a826514755ffa3031d780a7835b8a 390 Gene3D G3DSA:3.90.550.10 2 274 1.1E-24 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases ALX04_RS11660 236a826514755ffa3031d780a7835b8a 390 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 332 366 2.8E-4 T 28-03-2018 IPR001451 Hexapeptide repeat ALX04_RS11660 236a826514755ffa3031d780a7835b8a 390 SUPERFAMILY SSF51161 300 368 2.21E-12 T 28-03-2018 IPR011004 Trimeric LpxA-like ALX04_RS00945 ba749275919d0e600d223769a5c31fc4 444 Pfam PF00270 DEAD/DEAH box helicase 19 179 2.0E-39 T 28-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 ALX04_RS00945 ba749275919d0e600d223769a5c31fc4 444 Pfam PF00271 Helicase conserved C-terminal domain 226 326 1.4E-23 T 28-03-2018 IPR001650 Helicase, C-terminal ALX04_RS00945 ba749275919d0e600d223769a5c31fc4 444 SMART SM00490 245 326 3.2E-26 T 28-03-2018 IPR001650 Helicase, C-terminal ALX04_RS00945 ba749275919d0e600d223769a5c31fc4 444 SMART SM00487 13 205 9.5E-43 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain ALX04_RS00945 ba749275919d0e600d223769a5c31fc4 444 Gene3D G3DSA:3.40.50.300 212 444 2.6E-33 T 28-03-2018 ALX04_RS00945 ba749275919d0e600d223769a5c31fc4 444 SUPERFAMILY SSF52540 61 345 5.17E-55 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase ALX04_RS00945 ba749275919d0e600d223769a5c31fc4 444 ProSitePatterns PS00039 DEAD-box subfamily ATP-dependent helicases signature. 140 148 - T 28-03-2018 IPR000629 ATP-dependent RNA helicase DEAD-box, conserved site ALX04_RS00945 ba749275919d0e600d223769a5c31fc4 444 Gene3D G3DSA:3.40.50.300 5 211 7.4E-43 T 28-03-2018 ALX04_RS02690 e4db3f01a4d1d144c93724773037b61b 111 Gene3D G3DSA:3.30.70.1490 1 111 3.5E-30 T 28-03-2018 IPR007422 Cysteine protease Prp ALX04_RS02690 e4db3f01a4d1d144c93724773037b61b 111 Pfam PF04327 Cysteine protease Prp 1 104 1.2E-26 T 28-03-2018 IPR007422 Cysteine protease Prp ALX04_RS02690 e4db3f01a4d1d144c93724773037b61b 111 SUPERFAMILY SSF118010 1 108 4.32E-30 T 28-03-2018 IPR007422 Cysteine protease Prp ALX04_RS05285 e3da4a4f4a3a92f6f24e67715a041005 1143 SUPERFAMILY SSF56059 83 350 4.07E-67 T 28-03-2018 ALX04_RS05285 e3da4a4f4a3a92f6f24e67715a041005 1143 Pfam PF00682 HMGL-like 529 801 6.9E-28 T 28-03-2018 IPR000891 Pyruvate carboxyltransferase GO:0003824 ALX04_RS05285 e3da4a4f4a3a92f6f24e67715a041005 1143 SUPERFAMILY SSF51246 335 453 2.62E-37 T 28-03-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 ALX04_RS05285 e3da4a4f4a3a92f6f24e67715a041005 1143 Gene3D G3DSA:2.40.50.100 1063 1142 1.8E-20 T 28-03-2018 ALX04_RS05285 e3da4a4f4a3a92f6f24e67715a041005 1143 Gene3D G3DSA:3.10.600.10 987 1057 3.4E-18 T 28-03-2018 ALX04_RS05285 e3da4a4f4a3a92f6f24e67715a041005 1143 Gene3D G3DSA:3.10.600.10 460 528 1.7E-13 T 28-03-2018 ALX04_RS05285 e3da4a4f4a3a92f6f24e67715a041005 1143 Gene3D G3DSA:3.20.20.70 529 827 3.2E-71 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 ALX04_RS05285 e3da4a4f4a3a92f6f24e67715a041005 1143 Gene3D G3DSA:3.40.50.20 1 123 4.2E-50 T 28-03-2018 ALX04_RS05285 e3da4a4f4a3a92f6f24e67715a041005 1143 TIGRFAM TIGR01235 pyruv_carbox: pyruvate carboxylase 3 1140 0.0 T 28-03-2018 IPR005930 Pyruvate carboxylase GO:0004736|GO:0005524|GO:0006090|GO:0006094|GO:0009374 KEGG: 00020+6.4.1.1|KEGG: 00620+6.4.1.1|KEGG: 00720+6.4.1.1|MetaCyc: PWY-5750|MetaCyc: PWY-6142|MetaCyc: PWY-6146|Reactome: R-HSA-196780|Reactome: R-HSA-3371599|Reactome: R-HSA-70263 ALX04_RS05285 e3da4a4f4a3a92f6f24e67715a041005 1143 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 153 167 - T 28-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 ALX04_RS05285 e3da4a4f4a3a92f6f24e67715a041005 1143 SUPERFAMILY SSF89000 829 1006 1.69E-54 T 28-03-2018 ALX04_RS05285 e3da4a4f4a3a92f6f24e67715a041005 1143 PIRSF PIRSF001594 1 1142 0.0 T 28-03-2018 IPR005930 Pyruvate carboxylase GO:0004736|GO:0005524|GO:0006090|GO:0006094|GO:0009374 KEGG: 00020+6.4.1.1|KEGG: 00620+6.4.1.1|KEGG: 00720+6.4.1.1|MetaCyc: PWY-5750|MetaCyc: PWY-6142|MetaCyc: PWY-6146|Reactome: R-HSA-196780|Reactome: R-HSA-3371599|Reactome: R-HSA-70263 ALX04_RS05285 e3da4a4f4a3a92f6f24e67715a041005 1143 SMART SM00878 340 447 3.1E-51 T 28-03-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 ALX04_RS05285 e3da4a4f4a3a92f6f24e67715a041005 1143 Gene3D G3DSA:1.10.10.60 940 986 1.1E-18 T 28-03-2018 ALX04_RS05285 e3da4a4f4a3a92f6f24e67715a041005 1143 Pfam PF00364 Biotin-requiring enzyme 1075 1140 5.9E-18 T 28-03-2018 IPR000089 Biotin/lipoyl attachment ALX04_RS05285 e3da4a4f4a3a92f6f24e67715a041005 1143 Pfam PF02785 Biotin carboxylase C-terminal domain 340 448 1.4E-32 T 28-03-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 ALX04_RS05285 e3da4a4f4a3a92f6f24e67715a041005 1143 SUPERFAMILY SSF51569 521 832 7.51E-82 T 28-03-2018 ALX04_RS05285 e3da4a4f4a3a92f6f24e67715a041005 1143 SUPERFAMILY SSF52440 2 112 2.23E-42 T 28-03-2018 IPR016185 Pre-ATP-grasp domain ALX04_RS05285 e3da4a4f4a3a92f6f24e67715a041005 1143 Pfam PF02436 Conserved carboxylase domain 824 1024 2.4E-71 T 28-03-2018 IPR003379 Carboxylase, conserved domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599|Reactome: R-HSA-70263 ALX04_RS05285 e3da4a4f4a3a92f6f24e67715a041005 1143 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 285 292 - T 28-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 ALX04_RS05285 e3da4a4f4a3a92f6f24e67715a041005 1143 Pfam PF00289 Biotin carboxylase, N-terminal domain 2 110 6.8E-42 T 28-03-2018 IPR005481 Biotin carboxylase-like, N-terminal domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599 ALX04_RS05285 e3da4a4f4a3a92f6f24e67715a041005 1143 Gene3D G3DSA:3.30.470.20 210 449 2.0E-90 T 28-03-2018 ALX04_RS05285 e3da4a4f4a3a92f6f24e67715a041005 1143 Gene3D G3DSA:3.30.1490.20 124 209 7.6E-23 T 28-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 ALX04_RS05285 e3da4a4f4a3a92f6f24e67715a041005 1143 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 115 320 1.1E-75 T 28-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 ALX04_RS05285 e3da4a4f4a3a92f6f24e67715a041005 1143 SUPERFAMILY SSF51230 1063 1140 7.33E-21 T 28-03-2018 IPR011053 Single hybrid motif ALX04_RS04725 d71501f4d0d59b98b7ced897ac96847e 313 SUPERFAMILY SSF53448 2 258 1.62E-36 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases ALX04_RS04725 d71501f4d0d59b98b7ced897ac96847e 313 Pfam PF00535 Glycosyl transferase family 2 5 134 2.6E-24 T 28-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 ALX04_RS04725 d71501f4d0d59b98b7ced897ac96847e 313 Gene3D G3DSA:3.90.550.10 1 216 1.1E-27 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases ALX04_RS07250 fddabe5a90850c2d399cd0c20ccd0348 451 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 331 433 4.3E-14 T 28-03-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 ALX04_RS07250 fddabe5a90850c2d399cd0c20ccd0348 451 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 104 122 4.2E-22 T 28-03-2018 ALX04_RS07250 fddabe5a90850c2d399cd0c20ccd0348 451 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 236 252 4.2E-22 T 28-03-2018 ALX04_RS07250 fddabe5a90850c2d399cd0c20ccd0348 451 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 151 169 4.2E-22 T 28-03-2018 ALX04_RS07250 fddabe5a90850c2d399cd0c20ccd0348 451 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 3 22 4.2E-22 T 28-03-2018 ALX04_RS07250 fddabe5a90850c2d399cd0c20ccd0348 451 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 262 284 4.2E-22 T 28-03-2018 ALX04_RS07250 fddabe5a90850c2d399cd0c20ccd0348 451 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 151 176 9.5E-16 T 28-03-2018 ALX04_RS07250 fddabe5a90850c2d399cd0c20ccd0348 451 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 2 24 9.5E-16 T 28-03-2018 ALX04_RS07250 fddabe5a90850c2d399cd0c20ccd0348 451 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 277 284 9.5E-16 T 28-03-2018 ALX04_RS07250 fddabe5a90850c2d399cd0c20ccd0348 451 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 237 251 9.5E-16 T 28-03-2018 ALX04_RS07250 fddabe5a90850c2d399cd0c20ccd0348 451 Gene3D G3DSA:3.50.50.60 104 245 1.0E-30 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ALX04_RS07250 fddabe5a90850c2d399cd0c20ccd0348 451 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 2 307 7.8E-55 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ALX04_RS07250 fddabe5a90850c2d399cd0c20ccd0348 451 SUPERFAMILY SSF55424 326 447 4.98E-32 T 28-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 ALX04_RS07250 fddabe5a90850c2d399cd0c20ccd0348 451 Gene3D G3DSA:3.30.390.30 326 451 4.6E-20 T 28-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 ALX04_RS07250 fddabe5a90850c2d399cd0c20ccd0348 451 Gene3D G3DSA:3.50.50.60 246 325 4.2E-10 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ALX04_RS07250 fddabe5a90850c2d399cd0c20ccd0348 451 SUPERFAMILY SSF51905 1 316 2.39E-39 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ALX04_RS07250 fddabe5a90850c2d399cd0c20ccd0348 451 Gene3D G3DSA:3.50.50.60 1 103 5.8E-7 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ALX04_RS04040 ce4510e5b724a3f173321ae6c1aa5f7f 313 Pfam PF00005 ABC transporter 23 165 4.6E-30 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 ALX04_RS04040 ce4510e5b724a3f173321ae6c1aa5f7f 313 TIGRFAM TIGR01188 drrA: daunorubicin resistance ABC transporter, ATP-binding protein 14 309 2.4E-104 T 28-03-2018 IPR005894 Daunorubicin resistance ABC transporter ATP-binding subunit DrrA GO:0005524|GO:0043215|GO:1900753 ALX04_RS04040 ce4510e5b724a3f173321ae6c1aa5f7f 313 SMART SM00382 31 222 1.3E-9 T 28-03-2018 IPR003593 AAA+ ATPase domain ALX04_RS04040 ce4510e5b724a3f173321ae6c1aa5f7f 313 ProSitePatterns PS00211 ABC transporters family signature. 138 152 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 ALX04_RS04040 ce4510e5b724a3f173321ae6c1aa5f7f 313 Gene3D G3DSA:3.40.50.300 3 265 4.1E-67 T 28-03-2018 ALX04_RS04040 ce4510e5b724a3f173321ae6c1aa5f7f 313 SUPERFAMILY SSF52540 5 227 2.77E-61 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase ALX04_RS03305 964f6ffdb3e76cf1fee6137cfd385161 363 SUPERFAMILY SSF55060 210 352 1.7E-34 T 28-03-2018 IPR013750 GHMP kinase, C-terminal domain ALX04_RS03305 964f6ffdb3e76cf1fee6137cfd385161 363 Gene3D G3DSA:3.30.230.10 1 217 1.6E-50 T 28-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup ALX04_RS03305 964f6ffdb3e76cf1fee6137cfd385161 363 SUPERFAMILY SSF54211 1 227 4.33E-54 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold ALX04_RS03305 964f6ffdb3e76cf1fee6137cfd385161 363 TIGRFAM TIGR01220 Pmev_kin_Gr_pos: phosphomevalonate kinase 2 354 3.1E-137 T 28-03-2018 IPR005917 Phosphomevalonate kinase KEGG: 00900+2.7.4.2|MetaCyc: PWY-7391|MetaCyc: PWY-922 ALX04_RS03305 964f6ffdb3e76cf1fee6137cfd385161 363 PRINTS PR00959 Mevalonate kinase family signature 6 30 1.3E-8 T 28-03-2018 ALX04_RS03305 964f6ffdb3e76cf1fee6137cfd385161 363 PRINTS PR00959 Mevalonate kinase family signature 109 131 1.3E-8 T 28-03-2018 ALX04_RS03305 964f6ffdb3e76cf1fee6137cfd385161 363 PRINTS PR00959 Mevalonate kinase family signature 311 328 1.3E-8 T 28-03-2018 ALX04_RS03305 964f6ffdb3e76cf1fee6137cfd385161 363 Pfam PF00288 GHMP kinases N terminal domain 113 171 3.2E-17 T 28-03-2018 IPR006204 GHMP kinase N-terminal domain GO:0005524 ALX04_RS03305 964f6ffdb3e76cf1fee6137cfd385161 363 Pfam PF08544 GHMP kinases C terminal 278 329 7.0E-7 T 28-03-2018 IPR013750 GHMP kinase, C-terminal domain ALX04_RS03305 964f6ffdb3e76cf1fee6137cfd385161 363 Gene3D G3DSA:3.30.70.890 218 359 9.0E-26 T 28-03-2018 IPR013750 GHMP kinase, C-terminal domain ALX04_RS07370 4e14afe837042c8c391d1565e43fb997 209 Pfam PF06736 Protein of unknown function (DUF1211) 5 91 3.1E-25 T 28-03-2018 IPR010617 Endosomal/lysomomal potassium channel TMEM175 GO:0005267 ALX04_RS00215 65e927a1ea93d148023d78d672003667 154 Pfam PF13411 MerR HTH family regulatory protein 26 87 9.6E-12 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 ALX04_RS00215 65e927a1ea93d148023d78d672003667 154 SUPERFAMILY SSF46955 25 98 2.38E-15 T 28-03-2018 IPR009061 Putative DNA-binding domain ALX04_RS00215 65e927a1ea93d148023d78d672003667 154 Gene3D G3DSA:1.10.1660.10 22 138 1.5E-13 T 28-03-2018 ALX04_RS00215 65e927a1ea93d148023d78d672003667 154 SMART SM00422 24 94 2.3E-4 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 ALX04_RS09930 912006181163ca1186566a54360e5880 298 SUPERFAMILY SSF46785 6 111 7.27E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS09930 912006181163ca1186566a54360e5880 298 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 7 62 8.4E-16 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 ALX04_RS09930 912006181163ca1186566a54360e5880 298 Gene3D G3DSA:1.10.10.10 1 85 2.3E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS09930 912006181163ca1186566a54360e5880 298 SUPERFAMILY SSF53850 90 292 2.79E-27 T 28-03-2018 ALX04_RS09930 912006181163ca1186566a54360e5880 298 Pfam PF03466 LysR substrate binding domain 88 285 9.3E-27 T 28-03-2018 IPR005119 LysR, substrate-binding ALX04_RS09930 912006181163ca1186566a54360e5880 298 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 2.5E-5 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 ALX04_RS09930 912006181163ca1186566a54360e5880 298 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 2.5E-5 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 ALX04_RS09930 912006181163ca1186566a54360e5880 298 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 2.5E-5 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 ALX04_RS09930 912006181163ca1186566a54360e5880 298 Gene3D G3DSA:3.40.190.10 176 261 1.2E-7 T 28-03-2018 ALX04_RS09930 912006181163ca1186566a54360e5880 298 Gene3D G3DSA:3.40.190.10 91 175 1.7E-16 T 28-03-2018 ALX04_RS11460 ccb1a72a037718edb2cf7408d835b407 306 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 247 260 - T 28-03-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 ALX04_RS11460 ccb1a72a037718edb2cf7408d835b407 306 SUPERFAMILY SSF53613 1 302 7.48E-82 T 28-03-2018 IPR029056 Ribokinase-like ALX04_RS11460 ccb1a72a037718edb2cf7408d835b407 306 Hamap MF_01987 Ribokinase [rbsK]. 2 303 26.466 T 28-03-2018 IPR011877 Ribokinase GO:0004747|GO:0006014 KEGG: 00030+2.7.1.15|Reactome: R-HSA-71336 ALX04_RS11460 ccb1a72a037718edb2cf7408d835b407 306 PRINTS PR00990 Ribokinase signature 6 27 1.9E-32 T 28-03-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 ALX04_RS11460 ccb1a72a037718edb2cf7408d835b407 306 PRINTS PR00990 Ribokinase signature 33 52 1.9E-32 T 28-03-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 ALX04_RS11460 ccb1a72a037718edb2cf7408d835b407 306 PRINTS PR00990 Ribokinase signature 105 118 1.9E-32 T 28-03-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 ALX04_RS11460 ccb1a72a037718edb2cf7408d835b407 306 PRINTS PR00990 Ribokinase signature 218 229 1.9E-32 T 28-03-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 ALX04_RS11460 ccb1a72a037718edb2cf7408d835b407 306 PRINTS PR00990 Ribokinase signature 174 189 1.9E-32 T 28-03-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 ALX04_RS11460 ccb1a72a037718edb2cf7408d835b407 306 Pfam PF00294 pfkB family carbohydrate kinase 1 295 6.0E-66 T 28-03-2018 IPR011611 Carbohydrate kinase PfkB ALX04_RS11460 ccb1a72a037718edb2cf7408d835b407 306 TIGRFAM TIGR02152 D_ribokin_bact: ribokinase 4 301 5.1E-112 T 28-03-2018 IPR011877 Ribokinase GO:0004747|GO:0006014 KEGG: 00030+2.7.1.15|Reactome: R-HSA-71336 ALX04_RS11460 ccb1a72a037718edb2cf7408d835b407 306 Gene3D G3DSA:3.40.1190.20 2 305 1.6E-73 T 28-03-2018 IPR029056 Ribokinase-like ALX04_RS09575 a32f301a9012024b673507519558410f 160 TIGRFAM TIGR03715 KxYKxGKxW: KxYKxGKxW signal peptide 16 36 5.8E-10 T 28-03-2018 IPR022263 KxYKxGKxW signal peptide ALX04_RS08875 e4fe1fa0e5e3d1e3e03d81ff8ccb7c23 177 Pfam PF00358 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 11 128 1.2E-14 T 28-03-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 ALX04_RS08875 e4fe1fa0e5e3d1e3e03d81ff8ccb7c23 177 Gene3D G3DSA:2.70.70.10 6 156 6.5E-18 T 28-03-2018 ALX04_RS08875 e4fe1fa0e5e3d1e3e03d81ff8ccb7c23 177 SUPERFAMILY SSF51261 5 129 1.6E-20 T 28-03-2018 IPR011055 Duplicated hybrid motif ALX04_RS08825 b7c7b04ae5f364d52509587352f9650e 404 Gene3D G3DSA:1.20.1250.20 217 403 1.5E-6 T 28-03-2018 ALX04_RS08825 b7c7b04ae5f364d52509587352f9650e 404 Pfam PF07690 Major Facilitator Superfamily 14 367 1.7E-8 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 ALX04_RS08825 b7c7b04ae5f364d52509587352f9650e 404 SUPERFAMILY SSF103473 6 403 4.45E-24 T 28-03-2018 IPR020846 Major facilitator superfamily domain ALX04_RS08825 b7c7b04ae5f364d52509587352f9650e 404 Gene3D G3DSA:1.20.1250.20 1 194 1.4E-11 T 28-03-2018 ALX04_RS02715 b52a5b8640fa1a03c00ca1ce3066169e 139 SUPERFAMILY SSF48013 4 136 4.84E-36 T 28-03-2018 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 ALX04_RS02715 b52a5b8640fa1a03c00ca1ce3066169e 139 Hamap MF_00073 N utilization substance protein B homolog [nusB]. 3 138 22.797 T 28-03-2018 IPR011605 NusB antitermination factor GO:0006353 ALX04_RS02715 b52a5b8640fa1a03c00ca1ce3066169e 139 Pfam PF01029 NusB family 7 135 1.5E-35 T 28-03-2018 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 ALX04_RS02715 b52a5b8640fa1a03c00ca1ce3066169e 139 Gene3D G3DSA:1.10.940.10 2 139 6.2E-42 T 28-03-2018 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 ALX04_RS02715 b52a5b8640fa1a03c00ca1ce3066169e 139 TIGRFAM TIGR01951 nusB: transcription antitermination factor NusB 5 136 4.0E-40 T 28-03-2018 IPR011605 NusB antitermination factor GO:0006353 ALX04_RS12200 e55abdf707eed33b253086ceac1a0125 566 SUPERFAMILY SSF52540 4 237 9.41E-53 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase ALX04_RS12200 e55abdf707eed33b253086ceac1a0125 566 Pfam PF00005 ABC transporter 319 464 3.5E-31 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 ALX04_RS12200 e55abdf707eed33b253086ceac1a0125 566 Pfam PF00005 ABC transporter 23 173 5.2E-26 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 ALX04_RS12200 e55abdf707eed33b253086ceac1a0125 566 Pfam PF12558 ATP-binding cassette cobalt transporter 238 309 1.1E-18 T 28-03-2018 IPR022216 ABC cobalt transporter GO:0016820 ALX04_RS12200 e55abdf707eed33b253086ceac1a0125 566 SUPERFAMILY SSF52540 289 533 1.88E-58 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase ALX04_RS12200 e55abdf707eed33b253086ceac1a0125 566 SMART SM00382 327 513 1.7E-10 T 28-03-2018 IPR003593 AAA+ ATPase domain ALX04_RS12200 e55abdf707eed33b253086ceac1a0125 566 SMART SM00382 32 224 1.0E-13 T 28-03-2018 IPR003593 AAA+ ATPase domain ALX04_RS12200 e55abdf707eed33b253086ceac1a0125 566 ProSitePatterns PS00211 ABC transporters family signature. 146 160 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 ALX04_RS12200 e55abdf707eed33b253086ceac1a0125 566 Gene3D G3DSA:3.40.50.300 297 564 1.7E-57 T 28-03-2018 ALX04_RS12200 e55abdf707eed33b253086ceac1a0125 566 Gene3D G3DSA:3.40.50.300 1 242 3.3E-61 T 28-03-2018 ALX04_RS12200 e55abdf707eed33b253086ceac1a0125 566 ProSitePatterns PS00211 ABC transporters family signature. 436 450 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 ALX04_RS03490 4073a3fe0172ed14e73176b7d0af99d8 368 SUPERFAMILY SSF51905 3 215 2.2E-30 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ALX04_RS03490 4073a3fe0172ed14e73176b7d0af99d8 368 SUPERFAMILY SSF51905 306 355 2.2E-30 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ALX04_RS03490 4073a3fe0172ed14e73176b7d0af99d8 368 SUPERFAMILY SSF54373 215 305 5.36E-8 T 28-03-2018 ALX04_RS03490 4073a3fe0172ed14e73176b7d0af99d8 368 Gene3D G3DSA:3.50.50.60 1 362 3.4E-30 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ALX04_RS03490 4073a3fe0172ed14e73176b7d0af99d8 368 Pfam PF01266 FAD dependent oxidoreductase 5 344 3.8E-46 T 28-03-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 ALX04_RS02425 50c18d445753301725a0751d59f66fc4 244 Pfam PF13649 Methyltransferase domain 38 132 1.4E-17 T 28-03-2018 ALX04_RS02425 50c18d445753301725a0751d59f66fc4 244 SUPERFAMILY SSF53335 2 244 1.33E-47 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase ALX04_RS02425 50c18d445753301725a0751d59f66fc4 244 Gene3D G3DSA:3.40.50.150 2 135 2.4E-21 T 28-03-2018 ALX04_RS02425 50c18d445753301725a0751d59f66fc4 244 Gene3D G3DSA:2.20.25.110 140 203 6.3E-18 T 28-03-2018 ALX04_RS03695 e2a66e8e221bc118b1578a663a2b621a 145 PRINTS PR00598 Bacterial regulatory protein MarR family signature 69 84 1.3E-6 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 ALX04_RS03695 e2a66e8e221bc118b1578a663a2b621a 145 PRINTS PR00598 Bacterial regulatory protein MarR family signature 88 104 1.3E-6 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 ALX04_RS03695 e2a66e8e221bc118b1578a663a2b621a 145 PRINTS PR00598 Bacterial regulatory protein MarR family signature 52 68 1.3E-6 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 ALX04_RS03695 e2a66e8e221bc118b1578a663a2b621a 145 Gene3D G3DSA:1.10.10.10 2 143 5.3E-26 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS03695 e2a66e8e221bc118b1578a663a2b621a 145 SUPERFAMILY SSF46785 5 141 6.94E-32 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS03695 e2a66e8e221bc118b1578a663a2b621a 145 SMART SM00347 28 128 8.0E-25 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 ALX04_RS03695 e2a66e8e221bc118b1578a663a2b621a 145 Pfam PF01047 MarR family 35 92 9.9E-16 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 ALX04_RS05200 b72cd0a11f320d9af784116b18b3881e 421 Hamap MF_00175 ATP-dependent Clp protease ATP-binding subunit ClpX [clpX]. 5 417 52.21 T 28-03-2018 IPR004487 Clp protease, ATP-binding subunit ClpX GO:0005524|GO:0006457|GO:0051082 ALX04_RS05200 b72cd0a11f320d9af784116b18b3881e 421 Gene3D G3DSA:1.10.8.60 319 411 7.2E-35 T 28-03-2018 ALX04_RS05200 b72cd0a11f320d9af784116b18b3881e 421 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 319 397 7.9E-17 T 28-03-2018 IPR019489 Clp ATPase, C-terminal ALX04_RS05200 b72cd0a11f320d9af784116b18b3881e 421 SMART SM01086 319 415 2.7E-33 T 28-03-2018 IPR019489 Clp ATPase, C-terminal ALX04_RS05200 b72cd0a11f320d9af784116b18b3881e 421 TIGRFAM TIGR00382 clpX: ATP-dependent Clp protease, ATP-binding subunit ClpX 10 414 5.2E-200 T 28-03-2018 IPR004487 Clp protease, ATP-binding subunit ClpX GO:0005524|GO:0006457|GO:0051082 ALX04_RS05200 b72cd0a11f320d9af784116b18b3881e 421 Pfam PF06689 ClpX C4-type zinc finger 12 48 1.5E-18 T 28-03-2018 IPR010603 Zinc finger, ClpX C4-type GO:0008270|GO:0046983 ALX04_RS05200 b72cd0a11f320d9af784116b18b3881e 421 SUPERFAMILY SSF57716 12 46 5.7E-11 T 28-03-2018 ALX04_RS05200 b72cd0a11f320d9af784116b18b3881e 421 Gene3D G3DSA:3.40.50.300 53 317 3.9E-70 T 28-03-2018 ALX04_RS05200 b72cd0a11f320d9af784116b18b3881e 421 SMART SM00994 10 49 7.4E-21 T 28-03-2018 IPR010603 Zinc finger, ClpX C4-type GO:0008270|GO:0046983 ALX04_RS05200 b72cd0a11f320d9af784116b18b3881e 421 SUPERFAMILY SSF52540 60 406 2.49E-74 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase ALX04_RS05200 b72cd0a11f320d9af784116b18b3881e 421 SMART SM00382 113 275 1.3E-11 T 28-03-2018 IPR003593 AAA+ ATPase domain ALX04_RS05200 b72cd0a11f320d9af784116b18b3881e 421 Pfam PF07724 AAA domain (Cdc48 subfamily) 113 312 5.2E-49 T 28-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 ALX04_RS11835 05343ff38f6eaa335f133f99854be4a0 223 SUPERFAMILY SSF56784 6 213 3.4E-44 T 28-03-2018 IPR023214 HAD-like domain ALX04_RS11835 05343ff38f6eaa335f133f99854be4a0 223 Gene3D G3DSA:1.10.150.240 20 85 1.3E-18 T 28-03-2018 IPR023198 Phosphoglycolate phosphatase, domain 2 ALX04_RS11835 05343ff38f6eaa335f133f99854be4a0 223 TIGRFAM TIGR02009 PGMB-YQAB-SF: beta-phosphoglucomutase family hydrolase 7 194 1.2E-52 T 28-03-2018 IPR010976 Beta-phosphoglucomutase hydrolase ALX04_RS11835 05343ff38f6eaa335f133f99854be4a0 223 TIGRFAM TIGR01990 bPGM: beta-phosphoglucomutase 7 195 4.7E-78 T 28-03-2018 IPR010972 Beta-phosphoglucomutase GO:0000287|GO:0005975|GO:0008801 KEGG: 00500+5.4.2.6|MetaCyc: PWY-2721|MetaCyc: PWY-2722|MetaCyc: PWY-7459 ALX04_RS11835 05343ff38f6eaa335f133f99854be4a0 223 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 71 193 1.3E-16 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 ALX04_RS11835 05343ff38f6eaa335f133f99854be4a0 223 Gene3D G3DSA:3.40.50.1000 86 223 1.5E-19 T 28-03-2018 IPR023214 HAD-like domain ALX04_RS11835 05343ff38f6eaa335f133f99854be4a0 223 Pfam PF13419 Haloacid dehalogenase-like hydrolase 11 193 3.0E-23 T 28-03-2018 IPR023214 HAD-like domain ALX04_RS11835 05343ff38f6eaa335f133f99854be4a0 223 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 156 176 5.5E-5 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 ALX04_RS11835 05343ff38f6eaa335f133f99854be4a0 223 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 7 18 5.5E-5 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 ALX04_RS11835 05343ff38f6eaa335f133f99854be4a0 223 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 138 154 5.5E-5 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 ALX04_RS10500 99d39b0269a596f941aef5328136baf8 139 Pfam PF13463 Winged helix DNA-binding domain 28 97 2.7E-9 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 ALX04_RS10500 99d39b0269a596f941aef5328136baf8 139 Gene3D G3DSA:1.10.10.10 1 139 3.0E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS10500 99d39b0269a596f941aef5328136baf8 139 PRINTS PR00598 Bacterial regulatory protein MarR family signature 116 136 4.2E-6 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 ALX04_RS10500 99d39b0269a596f941aef5328136baf8 139 PRINTS PR00598 Bacterial regulatory protein MarR family signature 86 102 4.2E-6 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 ALX04_RS10500 99d39b0269a596f941aef5328136baf8 139 PRINTS PR00598 Bacterial regulatory protein MarR family signature 50 66 4.2E-6 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 ALX04_RS10500 99d39b0269a596f941aef5328136baf8 139 SMART SM00347 21 126 1.8E-5 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 ALX04_RS10500 99d39b0269a596f941aef5328136baf8 139 SUPERFAMILY SSF46785 2 137 5.96E-26 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS14910 f96e650387664d8c041a8160cec36087 271 SUPERFAMILY SSF56784 3 268 8.58E-53 T 28-03-2018 IPR023214 HAD-like domain ALX04_RS14910 f96e650387664d8c041a8160cec36087 271 TIGRFAM TIGR00099 Cof-subfamily: Cof-like hydrolase 5 263 6.2E-41 T 28-03-2018 IPR000150 Cof family GO:0016787 ALX04_RS14910 f96e650387664d8c041a8160cec36087 271 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 5 236 2.4E-20 T 28-03-2018 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 ALX04_RS14910 f96e650387664d8c041a8160cec36087 271 ProSitePatterns PS01229 Hypothetical cof family signature 2. 217 239 - T 28-03-2018 ALX04_RS14910 f96e650387664d8c041a8160cec36087 271 Gene3D G3DSA:3.40.50.1000 2 271 2.8E-27 T 28-03-2018 IPR023214 HAD-like domain ALX04_RS14910 f96e650387664d8c041a8160cec36087 271 Pfam PF08282 haloacid dehalogenase-like hydrolase 6 262 2.1E-42 T 28-03-2018 IPR023214 HAD-like domain ALX04_RS01575 1220ae8fad2bfba8c73750a35a152239 324 SUPERFAMILY SSF53800 3 313 1.06E-81 T 28-03-2018 ALX04_RS01575 1220ae8fad2bfba8c73750a35a152239 324 Gene3D G3DSA:3.40.50.1400 2 166 1.2E-37 T 28-03-2018 ALX04_RS01575 1220ae8fad2bfba8c73750a35a152239 324 ProSitePatterns PS00534 Ferrochelatase signature. 179 197 - T 28-03-2018 IPR019772 Ferrochelatase, active site GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 ALX04_RS01575 1220ae8fad2bfba8c73750a35a152239 324 Pfam PF00762 Ferrochelatase 4 310 1.1E-88 T 28-03-2018 IPR001015 Ferrochelatase GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 ALX04_RS01575 1220ae8fad2bfba8c73750a35a152239 324 TIGRFAM TIGR00109 hemH: ferrochelatase 4 311 2.3E-73 T 28-03-2018 IPR001015 Ferrochelatase GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 ALX04_RS01575 1220ae8fad2bfba8c73750a35a152239 324 Hamap MF_00323 Ferrochelatase [hemH]. 1 311 30.244 T 28-03-2018 IPR001015 Ferrochelatase GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 ALX04_RS01575 1220ae8fad2bfba8c73750a35a152239 324 Gene3D G3DSA:3.40.50.1400 167 291 1.7E-35 T 28-03-2018 ALX04_RS13060 d72f7eeb9f4cf7a7095974323961bd08 104 Pfam PF05495 CHY zinc finger 19 87 8.7E-7 T 28-03-2018 IPR008913 Zinc finger, CHY-type GO:0008270 Reactome: R-HSA-110320|Reactome: R-HSA-983168 ALX04_RS13060 d72f7eeb9f4cf7a7095974323961bd08 104 SUPERFAMILY SSF161219 9 90 4.05E-15 T 28-03-2018 ALX04_RS13060 d72f7eeb9f4cf7a7095974323961bd08 104 PIRSF PIRSF017292 4 104 2.5E-30 T 28-03-2018 IPR016694 Protein of unknown function UCP017292, zinc finger, CHY-type ALX04_RS02020 b04b62d29b496ee60edfd869f8416ea8 114 Hamap MF_01526 UPF0342 protein . 2 113 19.672 T 28-03-2018 IPR010368 Control of competence regulator ComK, YlbF/YmcA ALX04_RS02020 b04b62d29b496ee60edfd869f8416ea8 114 Pfam PF06133 Control of competence regulator ComK, YlbF/YmcA 5 108 6.4E-24 T 28-03-2018 IPR010368 Control of competence regulator ComK, YlbF/YmcA ALX04_RS02020 b04b62d29b496ee60edfd869f8416ea8 114 SUPERFAMILY SSF158622 3 113 4.71E-36 T 28-03-2018 IPR023378 YheA/YmcA-like domain ALX04_RS02020 b04b62d29b496ee60edfd869f8416ea8 114 Gene3D G3DSA:1.20.1500.10 4 109 2.5E-26 T 28-03-2018 IPR023378 YheA/YmcA-like domain ALX04_RS04050 fa20e710380d82ec54a614eb97c09ceb 798 Gene3D G3DSA:3.50.30.10 353 479 3.1E-40 T 28-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 ALX04_RS04050 fa20e710380d82ec54a614eb97c09ceb 798 SUPERFAMILY SSF52009 350 462 2.88E-33 T 28-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 ALX04_RS04050 fa20e710380d82ec54a614eb97c09ceb 798 Gene3D G3DSA:3.20.20.60 480 792 1.7E-78 T 28-03-2018 ALX04_RS04050 fa20e710380d82ec54a614eb97c09ceb 798 TIGRFAM TIGR01418 PEP_synth: phosphoenolpyruvate synthase 9 778 1.2E-286 T 28-03-2018 IPR006319 Phosphoenolpyruvate synthase GO:0006090|GO:0008986 KEGG: 00620+2.7.9.2|KEGG: 00680+2.7.9.2|KEGG: 00720+2.7.9.2|MetaCyc: PWY-5484 ALX04_RS04050 fa20e710380d82ec54a614eb97c09ceb 798 Pfam PF02896 PEP-utilising enzyme, TIM barrel domain 489 776 1.5E-66 T 28-03-2018 IPR000121 PEP-utilising enzyme, C-terminal GO:0016310|GO:0016772 ALX04_RS04050 fa20e710380d82ec54a614eb97c09ceb 798 SUPERFAMILY SSF56059 7 380 1.77E-97 T 28-03-2018 ALX04_RS04050 fa20e710380d82ec54a614eb97c09ceb 798 Pfam PF01326 Pyruvate phosphate dikinase, PEP/pyruvate binding domain 21 341 7.1E-114 T 28-03-2018 IPR002192 Pyruvate phosphate dikinase, PEP/pyruvate-binding GO:0005524|GO:0016301|GO:0016310 ALX04_RS04050 fa20e710380d82ec54a614eb97c09ceb 798 PIRSF PIRSF000854 3 782 1.1E-249 T 28-03-2018 IPR006319 Phosphoenolpyruvate synthase GO:0006090|GO:0008986 KEGG: 00620+2.7.9.2|KEGG: 00680+2.7.9.2|KEGG: 00720+2.7.9.2|MetaCyc: PWY-5484 ALX04_RS04050 fa20e710380d82ec54a614eb97c09ceb 798 Pfam PF00391 PEP-utilising enzyme, mobile domain 380 455 1.7E-25 T 28-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 ALX04_RS04050 fa20e710380d82ec54a614eb97c09ceb 798 SUPERFAMILY SSF51621 485 782 3.66E-86 T 28-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 ALX04_RS04050 fa20e710380d82ec54a614eb97c09ceb 798 ProSitePatterns PS00370 PEP-utilizing enzymes phosphorylation site signature. 410 421 - T 28-03-2018 IPR018274 PEP-utilising enzyme, active site GO:0016310|GO:0016772 ALX04_RS04050 fa20e710380d82ec54a614eb97c09ceb 798 Gene3D G3DSA:3.30.470.20 197 349 2.7E-40 T 28-03-2018 ALX04_RS04050 fa20e710380d82ec54a614eb97c09ceb 798 Gene3D G3DSA:3.30.1490.20 4 196 7.4E-53 T 28-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 ALX04_RS05925 239211746d47ec6f83eb6737bc701515 369 Gene3D G3DSA:3.40.350.10 4 140 1.1E-20 T 28-03-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal ALX04_RS05925 239211746d47ec6f83eb6737bc701515 369 Pfam PF00557 Metallopeptidase family M24 149 351 9.5E-57 T 28-03-2018 IPR000994 Peptidase M24 ALX04_RS05925 239211746d47ec6f83eb6737bc701515 369 Gene3D G3DSA:3.90.230.10 141 369 2.6E-69 T 28-03-2018 ALX04_RS05925 239211746d47ec6f83eb6737bc701515 369 SUPERFAMILY SSF53092 5 140 1.57E-29 T 28-03-2018 IPR028980 Creatinase/Aminopeptidase P, N-terminal ALX04_RS05925 239211746d47ec6f83eb6737bc701515 369 Pfam PF01321 Creatinase/Prolidase N-terminal domain 7 141 8.1E-21 T 28-03-2018 IPR000587 Creatinase, N-terminal GO:0016787 ALX04_RS05925 239211746d47ec6f83eb6737bc701515 369 SUPERFAMILY SSF55920 140 367 4.06E-74 T 28-03-2018 IPR000994 Peptidase M24 ALX04_RS10975 74b8b1c1102cb46a111b17e4b89089e0 525 Gene3D G3DSA:1.50.10.10 194 523 8.1E-41 T 28-03-2018 ALX04_RS10975 74b8b1c1102cb46a111b17e4b89089e0 525 SUPERFAMILY SSF48208 193 523 8.16E-32 T 28-03-2018 IPR008928 Six-hairpin glycosidase-like GO:0003824 ALX04_RS10975 74b8b1c1102cb46a111b17e4b89089e0 525 Pfam PF17389 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain 194 522 1.8E-20 T 28-03-2018 IPR035396 Alpha-L-rhamnosidase, six-hairpin glycosidase domain ALX04_RS02810 b94c8d48d66dbbcc5e71aaf4711b2632 248 SUPERFAMILY SSF81606 1 242 2.35E-65 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 ALX04_RS02810 b94c8d48d66dbbcc5e71aaf4711b2632 248 Pfam PF13672 Protein phosphatase 2C 12 213 7.6E-21 T 28-03-2018 ALX04_RS02810 b94c8d48d66dbbcc5e71aaf4711b2632 248 Gene3D G3DSA:3.60.40.10 1 239 1.3E-46 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 ALX04_RS02810 b94c8d48d66dbbcc5e71aaf4711b2632 248 SMART SM00331 7 241 2.1E-40 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 ALX04_RS02810 b94c8d48d66dbbcc5e71aaf4711b2632 248 SMART SM00332 1 239 2.8E-21 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 ALX04_RS14535 8d7922501f868b248496bc758572cf9d 787 SMART SM00958 226 338 9.3E-64 T 28-03-2018 IPR011130 SecA preprotein, cross-linking domain GO:0016020|GO:0017038 ALX04_RS14535 8d7922501f868b248496bc758572cf9d 787 Gene3D G3DSA:1.10.3060.10 679 787 3.0E-26 T 28-03-2018 ALX04_RS14535 8d7922501f868b248496bc758572cf9d 787 Gene3D G3DSA:1.10.3060.10 586 678 1.0E-26 T 28-03-2018 ALX04_RS14535 8d7922501f868b248496bc758572cf9d 787 ProSitePatterns PS01312 SecA family signature. 480 495 - T 28-03-2018 IPR020937 SecA conserved site GO:0006605|GO:0006886|GO:0016020 ALX04_RS14535 8d7922501f868b248496bc758572cf9d 787 SUPERFAMILY SSF52540 348 395 3.1E-79 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase ALX04_RS14535 8d7922501f868b248496bc758572cf9d 787 SUPERFAMILY SSF52540 5 226 3.1E-79 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase ALX04_RS14535 8d7922501f868b248496bc758572cf9d 787 SMART SM00957 5 382 4.9E-270 T 28-03-2018 IPR011115 SecA DEAD-like, N-terminal GO:0005524|GO:0016020|GO:0017038 ALX04_RS14535 8d7922501f868b248496bc758572cf9d 787 TIGRFAM TIGR00963 secA: preprotein translocase, SecA subunit 26 496 5.0E-236 T 28-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 ALX04_RS14535 8d7922501f868b248496bc758572cf9d 787 SUPERFAMILY SSF52540 396 567 3.89E-54 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase ALX04_RS14535 8d7922501f868b248496bc758572cf9d 787 Gene3D G3DSA:3.40.50.300 397 585 2.4E-54 T 28-03-2018 ALX04_RS14535 8d7922501f868b248496bc758572cf9d 787 SUPERFAMILY SSF81886 572 785 1.83E-70 T 28-03-2018 IPR011116 SecA Wing/Scaffold GO:0016020|GO:0017038 ALX04_RS14535 8d7922501f868b248496bc758572cf9d 787 Hamap MF_01382 Protein translocase subunit SecA [secA]. 4 782 19.239 T 28-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 ALX04_RS14535 8d7922501f868b248496bc758572cf9d 787 PRINTS PR00906 SecA protein signature 393 406 1.2E-70 T 28-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 ALX04_RS14535 8d7922501f868b248496bc758572cf9d 787 PRINTS PR00906 SecA protein signature 319 341 1.2E-70 T 28-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 ALX04_RS14535 8d7922501f868b248496bc758572cf9d 787 PRINTS PR00906 SecA protein signature 356 373 1.2E-70 T 28-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 ALX04_RS14535 8d7922501f868b248496bc758572cf9d 787 PRINTS PR00906 SecA protein signature 168 188 1.2E-70 T 28-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 ALX04_RS14535 8d7922501f868b248496bc758572cf9d 787 PRINTS PR00906 SecA protein signature 115 125 1.2E-70 T 28-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 ALX04_RS14535 8d7922501f868b248496bc758572cf9d 787 PRINTS PR00906 SecA protein signature 61 85 1.2E-70 T 28-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 ALX04_RS14535 8d7922501f868b248496bc758572cf9d 787 PRINTS PR00906 SecA protein signature 99 113 1.2E-70 T 28-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 ALX04_RS14535 8d7922501f868b248496bc758572cf9d 787 SUPERFAMILY SSF81767 225 348 1.83E-45 T 28-03-2018 IPR011130 SecA preprotein, cross-linking domain GO:0016020|GO:0017038 ALX04_RS14535 8d7922501f868b248496bc758572cf9d 787 Pfam PF07516 SecA Wing and Scaffold domain 570 778 3.3E-61 T 28-03-2018 IPR011116 SecA Wing/Scaffold GO:0016020|GO:0017038 ALX04_RS14535 8d7922501f868b248496bc758572cf9d 787 Pfam PF01043 SecA preprotein cross-linking domain 231 338 1.1E-36 T 28-03-2018 IPR011130 SecA preprotein, cross-linking domain GO:0016020|GO:0017038 ALX04_RS14535 8d7922501f868b248496bc758572cf9d 787 Pfam PF07517 SecA DEAD-like domain 8 382 2.7E-125 T 28-03-2018 IPR011115 SecA DEAD-like, N-terminal GO:0005524|GO:0016020|GO:0017038 ALX04_RS14535 8d7922501f868b248496bc758572cf9d 787 Gene3D G3DSA:3.40.50.300 288 396 1.7E-9 T 28-03-2018 ALX04_RS14535 8d7922501f868b248496bc758572cf9d 787 Gene3D G3DSA:3.40.50.300 8 268 6.0E-49 T 28-03-2018 ALX04_RS05405 f8bd33af8e6d300b944f78d0eeadff7e 482 Pfam PF02368 Bacterial Ig-like domain (group 2) 157 241 1.1E-7 T 28-03-2018 IPR003343 Bacterial Ig-like, group 2 ALX04_RS05405 f8bd33af8e6d300b944f78d0eeadff7e 482 Pfam PF13731 WxL domain surface cell wall-binding 325 443 2.7E-10 T 28-03-2018 IPR027994 WxL domain ALX04_RS05405 f8bd33af8e6d300b944f78d0eeadff7e 482 Gene3D G3DSA:2.60.40.1080 153 237 1.2E-13 T 28-03-2018 ALX04_RS05405 f8bd33af8e6d300b944f78d0eeadff7e 482 SUPERFAMILY SSF49373 155 243 1.73E-7 T 28-03-2018 IPR008964 Invasin/intimin cell-adhesion fragments ALX04_RS05405 f8bd33af8e6d300b944f78d0eeadff7e 482 Gene3D G3DSA:2.60.40.10 238 361 0.0095 T 28-03-2018 IPR013783 Immunoglobulin-like fold ALX04_RS09000 4600128605e87fa976b715b7b9ff890a 617 SUPERFAMILY SSF49401 170 312 2.39E-20 T 28-03-2018 IPR008966 Adhesion domain ALX04_RS09000 4600128605e87fa976b715b7b9ff890a 617 Pfam PF05737 Collagen binding domain 171 288 9.5E-16 T 28-03-2018 IPR008456 Collagen binding domain GO:0005518 ALX04_RS09000 4600128605e87fa976b715b7b9ff890a 617 SUPERFAMILY SSF49401 48 154 1.62E-16 T 28-03-2018 IPR008966 Adhesion domain ALX04_RS09000 4600128605e87fa976b715b7b9ff890a 617 Gene3D G3DSA:2.60.40.1280 31 184 8.9E-20 T 28-03-2018 IPR011252 Fibrogen-binding domain 1 GO:0005618|GO:0007155 ALX04_RS12575 3eb50c00ba54d11c7b9f5009bd092518 385 Pfam PF08125 Mannitol dehydrogenase C-terminal domain 150 371 1.5E-62 T 28-03-2018 IPR013118 Mannitol dehydrogenase, C-terminal GO:0016491|GO:0050662|GO:0055114 ALX04_RS12575 3eb50c00ba54d11c7b9f5009bd092518 385 Gene3D G3DSA:3.40.50.720 3 73 1.9E-6 T 28-03-2018 ALX04_RS12575 3eb50c00ba54d11c7b9f5009bd092518 385 Gene3D G3DSA:3.40.50.720 74 201 1.7E-29 T 28-03-2018 ALX04_RS12575 3eb50c00ba54d11c7b9f5009bd092518 385 PRINTS PR00084 Mannitol dehydrogenase signature 170 185 2.4E-19 T 28-03-2018 IPR000669 Mannitol dehydrogenase GO:0003824|GO:0008152|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 ALX04_RS12575 3eb50c00ba54d11c7b9f5009bd092518 385 PRINTS PR00084 Mannitol dehydrogenase signature 116 129 2.4E-19 T 28-03-2018 IPR000669 Mannitol dehydrogenase GO:0003824|GO:0008152|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 ALX04_RS12575 3eb50c00ba54d11c7b9f5009bd092518 385 PRINTS PR00084 Mannitol dehydrogenase signature 152 165 2.4E-19 T 28-03-2018 IPR000669 Mannitol dehydrogenase GO:0003824|GO:0008152|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 ALX04_RS12575 3eb50c00ba54d11c7b9f5009bd092518 385 PRINTS PR00084 Mannitol dehydrogenase signature 3 13 2.4E-19 T 28-03-2018 IPR000669 Mannitol dehydrogenase GO:0003824|GO:0008152|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 ALX04_RS12575 3eb50c00ba54d11c7b9f5009bd092518 385 SUPERFAMILY SSF48179 204 376 1.7E-43 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 ALX04_RS12575 3eb50c00ba54d11c7b9f5009bd092518 385 SUPERFAMILY SSF51735 4 197 1.1E-45 T 28-03-2018 IPR016040 NAD(P)-binding domain ALX04_RS12575 3eb50c00ba54d11c7b9f5009bd092518 385 Gene3D G3DSA:1.10.1040.10 207 381 3.1E-37 T 28-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 ALX04_RS12575 3eb50c00ba54d11c7b9f5009bd092518 385 Pfam PF01232 Mannitol dehydrogenase Rossmann domain 4 125 2.1E-24 T 28-03-2018 IPR013131 Mannitol dehydrogenase, N-terminal GO:0016491|GO:0055114 ALX04_RS12575 3eb50c00ba54d11c7b9f5009bd092518 385 Hamap MF_00196 Mannitol-1-phosphate 5-dehydrogenase [mtlD]. 1 378 40.76 T 28-03-2018 IPR023028 Mannitol-1-phosphate 5-dehydrogenase GO:0008926|GO:0019594|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 ALX04_RS01560 550994d5bc28d9f35a4f2f5fab23b0f6 278 Gene3D G3DSA:3.60.21.10 1 258 5.2E-35 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like ALX04_RS01560 550994d5bc28d9f35a4f2f5fab23b0f6 278 SUPERFAMILY SSF56300 1 240 1.21E-48 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like ALX04_RS01560 550994d5bc28d9f35a4f2f5fab23b0f6 278 PIRSF PIRSF000883 2 251 1.6E-55 T 28-03-2018 IPR011152 Phosphoesterase MJ0912 ALX04_RS01560 550994d5bc28d9f35a4f2f5fab23b0f6 278 Pfam PF12850 Calcineurin-like phosphoesterase superfamily domain 3 207 1.8E-17 T 28-03-2018 IPR024654 Calcineurin-like phosphoesterase domain, lpxH type Reactome: R-HSA-3238698 ALX04_RS03325 0f83aee8b7155217f8f934bfc95f8755 934 TIGRFAM TIGR01407 dinG_rel: putative DnaQ family exonuclease/DinG family helicase 6 931 2.2E-225 T 28-03-2018 IPR006310 DnaQ exonuclease/DinG helicase, predicted ALX04_RS03325 0f83aee8b7155217f8f934bfc95f8755 934 Gene3D G3DSA:3.40.50.300 731 927 1.2E-10 T 28-03-2018 ALX04_RS03325 0f83aee8b7155217f8f934bfc95f8755 934 SUPERFAMILY SSF53098 4 185 5.38E-50 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 ALX04_RS03325 0f83aee8b7155217f8f934bfc95f8755 934 SMART SM00479 6 173 1.6E-35 T 28-03-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III ALX04_RS03325 0f83aee8b7155217f8f934bfc95f8755 934 Pfam PF13307 Helicase C-terminal domain 748 911 1.9E-35 T 28-03-2018 IPR006555 ATP-dependent helicase, C-terminal GO:0003676|GO:0005524|GO:0006139|GO:0008026|GO:0016818 ALX04_RS03325 0f83aee8b7155217f8f934bfc95f8755 934 Pfam PF00929 Exonuclease 9 164 9.7E-24 T 28-03-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III ALX04_RS03325 0f83aee8b7155217f8f934bfc95f8755 934 Gene3D G3DSA:3.30.420.10 1 175 8.8E-37 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 ALX04_RS03325 0f83aee8b7155217f8f934bfc95f8755 934 SMART SM00491 765 898 9.2E-23 T 28-03-2018 IPR006555 ATP-dependent helicase, C-terminal GO:0003676|GO:0005524|GO:0006139|GO:0008026|GO:0016818 ALX04_RS03325 0f83aee8b7155217f8f934bfc95f8755 934 SUPERFAMILY SSF52540 427 479 3.55E-18 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase ALX04_RS03325 0f83aee8b7155217f8f934bfc95f8755 934 SUPERFAMILY SSF52540 857 893 3.55E-18 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase ALX04_RS03325 0f83aee8b7155217f8f934bfc95f8755 934 SUPERFAMILY SSF52540 254 352 3.55E-18 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase ALX04_RS03325 0f83aee8b7155217f8f934bfc95f8755 934 Gene3D G3DSA:3.40.50.300 254 641 2.7E-22 T 28-03-2018 ALX04_RS03325 0f83aee8b7155217f8f934bfc95f8755 934 SUPERFAMILY SSF52540 735 837 5.14E-7 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase ALX04_RS03325 0f83aee8b7155217f8f934bfc95f8755 934 SUPERFAMILY SSF52540 868 893 5.14E-7 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase ALX04_RS15435 c006ff5ff490925c538114738a957984 842 Gene3D G3DSA:3.40.50.510 464 614 2.1E-15 T 28-03-2018 IPR004701 Phosphotransferase system, mannose-type IIA component GO:0009401|GO:0016021 ALX04_RS15435 c006ff5ff490925c538114738a957984 842 SUPERFAMILY SSF53062 481 595 4.45E-10 T 28-03-2018 IPR004701 Phosphotransferase system, mannose-type IIA component GO:0009401|GO:0016021 ALX04_RS15435 c006ff5ff490925c538114738a957984 842 Gene3D G3DSA:3.40.50.2300 615 706 3.9E-11 T 28-03-2018 ALX04_RS15435 c006ff5ff490925c538114738a957984 842 SUPERFAMILY SSF52540 58 290 2.59E-11 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase ALX04_RS15435 c006ff5ff490925c538114738a957984 842 Gene3D G3DSA:1.10.10.10 2 65 1.3E-9 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS15435 c006ff5ff490925c538114738a957984 842 Pfam PF00874 PRD domain 747 835 6.3E-10 T 28-03-2018 IPR011608 PRD domain GO:0006355 ALX04_RS15435 c006ff5ff490925c538114738a957984 842 Gene3D G3DSA:1.10.1790.10 739 841 1.3E-10 T 28-03-2018 IPR011608 PRD domain GO:0006355 ALX04_RS15435 c006ff5ff490925c538114738a957984 842 SUPERFAMILY SSF63520 742 840 2.49E-11 T 28-03-2018 IPR011608 PRD domain GO:0006355 ALX04_RS15435 c006ff5ff490925c538114738a957984 842 Gene3D G3DSA:1.10.1790.10 374 460 0.45 T 28-03-2018 IPR011608 PRD domain GO:0006355 ALX04_RS15435 c006ff5ff490925c538114738a957984 842 Pfam PF14532 Sigma-54 interaction domain 79 211 1.1E-7 T 28-03-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 ALX04_RS15435 c006ff5ff490925c538114738a957984 842 Gene3D G3DSA:3.40.50.300 78 227 1.7E-6 T 28-03-2018 ALX04_RS06425 1ba0780d34869f5ec7e6bf4f0a9ee873 181 TIGRFAM TIGR01145 ATP_synt_delta: ATP synthase F1, delta subunit 8 178 4.6E-40 T 28-03-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 ALX04_RS06425 1ba0780d34869f5ec7e6bf4f0a9ee873 181 SUPERFAMILY SSF47928 5 107 1.27E-25 T 28-03-2018 IPR026015 F1F0 ATP synthase OSCP/delta subunit, N-terminal domain Reactome: R-HSA-163210|Reactome: R-HSA-8949613 ALX04_RS06425 1ba0780d34869f5ec7e6bf4f0a9ee873 181 ProSitePatterns PS00389 ATP synthase delta (OSCP) subunit signature. 140 159 - T 28-03-2018 IPR020781 ATPase, OSCP/delta subunit, conserved site GO:0015986|GO:0016020|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 ALX04_RS06425 1ba0780d34869f5ec7e6bf4f0a9ee873 181 Hamap MF_01416 ATP synthase subunit delta [atpD]. 4 180 19.581 T 28-03-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 ALX04_RS06425 1ba0780d34869f5ec7e6bf4f0a9ee873 181 PRINTS PR00125 ATP synthase delta subunit signature 138 153 6.2E-21 T 28-03-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 ALX04_RS06425 1ba0780d34869f5ec7e6bf4f0a9ee873 181 PRINTS PR00125 ATP synthase delta subunit signature 87 101 6.2E-21 T 28-03-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 ALX04_RS06425 1ba0780d34869f5ec7e6bf4f0a9ee873 181 PRINTS PR00125 ATP synthase delta subunit signature 76 87 6.2E-21 T 28-03-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 ALX04_RS06425 1ba0780d34869f5ec7e6bf4f0a9ee873 181 PRINTS PR00125 ATP synthase delta subunit signature 8 27 6.2E-21 T 28-03-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 ALX04_RS06425 1ba0780d34869f5ec7e6bf4f0a9ee873 181 PRINTS PR00125 ATP synthase delta subunit signature 153 171 6.2E-21 T 28-03-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 ALX04_RS06425 1ba0780d34869f5ec7e6bf4f0a9ee873 181 Gene3D G3DSA:1.10.520.20 4 108 1.4E-22 T 28-03-2018 IPR026015 F1F0 ATP synthase OSCP/delta subunit, N-terminal domain Reactome: R-HSA-163210|Reactome: R-HSA-8949613 ALX04_RS06425 1ba0780d34869f5ec7e6bf4f0a9ee873 181 Pfam PF00213 ATP synthase delta (OSCP) subunit 8 178 1.2E-50 T 28-03-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 ALX04_RS11445 676f96580ebd170a8b9fa27fa073a7db 267 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 180 197 1.3E-36 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR ALX04_RS11445 676f96580ebd170a8b9fa27fa073a7db 267 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 12 29 1.3E-36 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR ALX04_RS11445 676f96580ebd170a8b9fa27fa073a7db 267 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 133 149 1.3E-36 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR ALX04_RS11445 676f96580ebd170a8b9fa27fa073a7db 267 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 77 88 1.3E-36 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR ALX04_RS11445 676f96580ebd170a8b9fa27fa073a7db 267 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 228 248 1.3E-36 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR ALX04_RS11445 676f96580ebd170a8b9fa27fa073a7db 267 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 159 178 1.3E-36 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR ALX04_RS11445 676f96580ebd170a8b9fa27fa073a7db 267 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 11 194 0.0084 T 28-03-2018 ALX04_RS11445 676f96580ebd170a8b9fa27fa073a7db 267 SUPERFAMILY SSF51735 10 264 4.57E-67 T 28-03-2018 IPR016040 NAD(P)-binding domain ALX04_RS11445 676f96580ebd170a8b9fa27fa073a7db 267 Pfam PF00106 short chain dehydrogenase 11 203 7.7E-52 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR ALX04_RS11445 676f96580ebd170a8b9fa27fa073a7db 267 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 159 178 1.1E-12 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR ALX04_RS11445 676f96580ebd170a8b9fa27fa073a7db 267 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 77 88 1.1E-12 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR ALX04_RS11445 676f96580ebd170a8b9fa27fa073a7db 267 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 139 147 1.1E-12 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR ALX04_RS11445 676f96580ebd170a8b9fa27fa073a7db 267 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 146 174 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 ALX04_RS11445 676f96580ebd170a8b9fa27fa073a7db 267 Gene3D G3DSA:3.40.50.720 9 267 9.5E-63 T 28-03-2018 ALX04_RS11020 c238581ee39a75ee8c4baf9f11188936 626 SUPERFAMILY SSF49303 229 329 2.48E-21 T 28-03-2018 IPR006102 Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich GO:0004553|GO:0005975 ALX04_RS11020 c238581ee39a75ee8c4baf9f11188936 626 ProSitePatterns PS00608 Glycosyl hydrolases family 2 acid/base catalyst. 452 466 - T 28-03-2018 IPR023232 Glycoside hydrolase, family 2, active site KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-6798695 ALX04_RS11020 c238581ee39a75ee8c4baf9f11188936 626 Pfam PF00703 Glycosyl hydrolases family 2 229 329 1.3E-13 T 28-03-2018 IPR006102 Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich GO:0004553|GO:0005975 ALX04_RS11020 c238581ee39a75ee8c4baf9f11188936 626 Gene3D G3DSA:3.20.20.80 330 622 8.7E-56 T 28-03-2018 ALX04_RS11020 c238581ee39a75ee8c4baf9f11188936 626 Gene3D G3DSA:2.60.40.10 228 329 2.2E-20 T 28-03-2018 IPR013783 Immunoglobulin-like fold ALX04_RS11020 c238581ee39a75ee8c4baf9f11188936 626 SUPERFAMILY SSF49785 6 226 3.83E-56 T 28-03-2018 IPR008979 Galactose-binding domain-like ALX04_RS11020 c238581ee39a75ee8c4baf9f11188936 626 SUPERFAMILY SSF51445 335 622 1.0E-77 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily ALX04_RS11020 c238581ee39a75ee8c4baf9f11188936 626 Gene3D G3DSA:2.60.120.260 1 226 3.3E-55 T 28-03-2018 IPR008979 Galactose-binding domain-like ALX04_RS11020 c238581ee39a75ee8c4baf9f11188936 626 ProSitePatterns PS00719 Glycosyl hydrolases family 2 signature 1. 382 407 - T 28-03-2018 IPR023230 Glycoside hydrolase, family 2, conserved site KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-6798695 ALX04_RS11020 c238581ee39a75ee8c4baf9f11188936 626 Pfam PF02837 Glycosyl hydrolases family 2, sugar binding domain 41 226 1.2E-31 T 28-03-2018 IPR006104 Glycosyl hydrolases family 2, sugar binding domain GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 ALX04_RS11020 c238581ee39a75ee8c4baf9f11188936 626 PRINTS PR00132 Glycosyl hydrolase family 2 signature 341 355 5.6E-32 T 28-03-2018 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-6798695 ALX04_RS11020 c238581ee39a75ee8c4baf9f11188936 626 PRINTS PR00132 Glycosyl hydrolase family 2 signature 154 169 5.6E-32 T 28-03-2018 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-6798695 ALX04_RS11020 c238581ee39a75ee8c4baf9f11188936 626 PRINTS PR00132 Glycosyl hydrolase family 2 signature 372 390 5.6E-32 T 28-03-2018 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-6798695 ALX04_RS11020 c238581ee39a75ee8c4baf9f11188936 626 PRINTS PR00132 Glycosyl hydrolase family 2 signature 452 467 5.6E-32 T 28-03-2018 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-6798695 ALX04_RS11020 c238581ee39a75ee8c4baf9f11188936 626 PRINTS PR00132 Glycosyl hydrolase family 2 signature 528 543 5.6E-32 T 28-03-2018 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-6798695 ALX04_RS11020 c238581ee39a75ee8c4baf9f11188936 626 Pfam PF02836 Glycosyl hydrolases family 2, TIM barrel domain 331 623 3.9E-130 T 28-03-2018 IPR006103 Glycoside hydrolase family 2, catalytic domain GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-6798695 ALX04_RS05095 9d9d0557bded03cfe73f9d48f03cec24 251 Pfam PF00455 DeoR C terminal sensor domain 75 231 2.9E-45 T 28-03-2018 IPR014036 DeoR C-terminal sensor domain ALX04_RS05095 9d9d0557bded03cfe73f9d48f03cec24 251 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 24 38 1.3E-6 T 28-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 ALX04_RS05095 9d9d0557bded03cfe73f9d48f03cec24 251 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 38 56 1.3E-6 T 28-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 ALX04_RS05095 9d9d0557bded03cfe73f9d48f03cec24 251 SUPERFAMILY SSF100950 74 228 1.36E-29 T 28-03-2018 ALX04_RS05095 9d9d0557bded03cfe73f9d48f03cec24 251 Gene3D G3DSA:1.10.10.10 1 63 1.3E-10 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS05095 9d9d0557bded03cfe73f9d48f03cec24 251 SMART SM01134 73 232 9.4E-65 T 28-03-2018 ALX04_RS05095 9d9d0557bded03cfe73f9d48f03cec24 251 Pfam PF08220 DeoR-like helix-turn-helix domain 6 61 6.5E-15 T 28-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 ALX04_RS05095 9d9d0557bded03cfe73f9d48f03cec24 251 Gene3D G3DSA:3.40.50.1360 66 248 5.5E-38 T 28-03-2018 ALX04_RS05095 9d9d0557bded03cfe73f9d48f03cec24 251 ProSitePatterns PS00894 DeoR-type HTH domain signature. 6 40 - T 28-03-2018 IPR018356 Transcription regulator, HTH DeoR-type, conserved site GO:0003700|GO:0006355 ALX04_RS05095 9d9d0557bded03cfe73f9d48f03cec24 251 SUPERFAMILY SSF46785 4 76 3.64E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS05095 9d9d0557bded03cfe73f9d48f03cec24 251 SMART SM00420 6 58 8.7E-15 T 28-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 ALX04_RS11015 2db715f3da7e4cb9b3dab9601c40060e 387 Gene3D G3DSA:3.30.230.10 2 207 1.7E-52 T 28-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup ALX04_RS11015 2db715f3da7e4cb9b3dab9601c40060e 387 Pfam PF10509 Galactokinase galactose-binding signature 8 57 1.8E-21 T 28-03-2018 IPR019539 Galactokinase galactose-binding domain GO:0005534 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 ALX04_RS11015 2db715f3da7e4cb9b3dab9601c40060e 387 Hamap MF_00246 Galactokinase [galK]. 24 386 48.345 T 28-03-2018 IPR022963 Galactokinase, bacterial GO:0004335|GO:0006012 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 ALX04_RS11015 2db715f3da7e4cb9b3dab9601c40060e 387 Gene3D G3DSA:3.30.70.890 208 377 7.4E-49 T 28-03-2018 IPR013750 GHMP kinase, C-terminal domain ALX04_RS11015 2db715f3da7e4cb9b3dab9601c40060e 387 PRINTS PR00959 Mevalonate kinase family signature 333 350 3.0E-42 T 28-03-2018 ALX04_RS11015 2db715f3da7e4cb9b3dab9601c40060e 387 PRINTS PR00959 Mevalonate kinase family signature 119 141 3.0E-42 T 28-03-2018 ALX04_RS11015 2db715f3da7e4cb9b3dab9601c40060e 387 PRINTS PR00959 Mevalonate kinase family signature 24 48 3.0E-42 T 28-03-2018 ALX04_RS11015 2db715f3da7e4cb9b3dab9601c40060e 387 PRINTS PR00959 Mevalonate kinase family signature 162 181 3.0E-42 T 28-03-2018 ALX04_RS11015 2db715f3da7e4cb9b3dab9601c40060e 387 SUPERFAMILY SSF54211 4 203 3.87E-61 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold ALX04_RS11015 2db715f3da7e4cb9b3dab9601c40060e 387 PIRSF PIRSF000530 1 387 2.0E-119 T 28-03-2018 IPR006206 Mevalonate/galactokinase GO:0005524|GO:0005737|GO:0008152|GO:0016301|GO:0016773 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 ALX04_RS11015 2db715f3da7e4cb9b3dab9601c40060e 387 Pfam PF00288 GHMP kinases N terminal domain 114 181 3.4E-11 T 28-03-2018 IPR006204 GHMP kinase N-terminal domain GO:0005524 ALX04_RS11015 2db715f3da7e4cb9b3dab9601c40060e 387 TIGRFAM TIGR00131 gal_kin: galactokinase 5 384 5.4E-117 T 28-03-2018 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 ALX04_RS11015 2db715f3da7e4cb9b3dab9601c40060e 387 SUPERFAMILY SSF55060 206 385 9.36E-56 T 28-03-2018 IPR013750 GHMP kinase, C-terminal domain ALX04_RS11015 2db715f3da7e4cb9b3dab9601c40060e 387 ProSitePatterns PS00627 GHMP kinases putative ATP-binding domain. 121 132 - T 28-03-2018 IPR006203 GHMP kinase, ATP-binding, conserved site GO:0005524 ALX04_RS11015 2db715f3da7e4cb9b3dab9601c40060e 387 ProSitePatterns PS00106 Galactokinase signature. 26 37 - T 28-03-2018 IPR019741 Galactokinase, conserved site KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 ALX04_RS11015 2db715f3da7e4cb9b3dab9601c40060e 387 PRINTS PR00473 Galactokinase signature 91 102 2.5E-26 T 28-03-2018 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 ALX04_RS11015 2db715f3da7e4cb9b3dab9601c40060e 387 PRINTS PR00473 Galactokinase signature 112 130 2.5E-26 T 28-03-2018 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 ALX04_RS11015 2db715f3da7e4cb9b3dab9601c40060e 387 PRINTS PR00473 Galactokinase signature 269 283 2.5E-26 T 28-03-2018 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 ALX04_RS11015 2db715f3da7e4cb9b3dab9601c40060e 387 PRINTS PR00473 Galactokinase signature 26 44 2.5E-26 T 28-03-2018 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 ALX04_RS11015 2db715f3da7e4cb9b3dab9601c40060e 387 Pfam PF08544 GHMP kinases C terminal 285 366 3.4E-12 T 28-03-2018 IPR013750 GHMP kinase, C-terminal domain ALX04_RS11715 9a8e81978c4a3c03ac4d8811bc4319b9 235 Gene3D G3DSA:3.40.50.2300 1 116 2.3E-38 T 28-03-2018 ALX04_RS11715 9a8e81978c4a3c03ac4d8811bc4319b9 235 Pfam PF00072 Response regulator receiver domain 4 113 1.0E-31 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 ALX04_RS11715 9a8e81978c4a3c03ac4d8811bc4319b9 235 SUPERFAMILY SSF46894 131 230 1.62E-31 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 ALX04_RS11715 9a8e81978c4a3c03ac4d8811bc4319b9 235 SMART SM00448 2 112 9.2E-48 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 ALX04_RS11715 9a8e81978c4a3c03ac4d8811bc4319b9 235 SMART SM00862 153 229 2.4E-27 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 ALX04_RS11715 9a8e81978c4a3c03ac4d8811bc4319b9 235 SUPERFAMILY SSF52172 1 126 2.99E-44 T 28-03-2018 IPR011006 CheY-like superfamily ALX04_RS11715 9a8e81978c4a3c03ac4d8811bc4319b9 235 Pfam PF00486 Transcriptional regulatory protein, C terminal 153 229 2.2E-27 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 ALX04_RS11715 9a8e81978c4a3c03ac4d8811bc4319b9 235 Gene3D G3DSA:1.10.10.10 117 235 3.2E-34 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS13850 c5608bbb7598fe62ca895dbb88b8b8f1 745 SUPERFAMILY SSF52540 180 426 1.18E-73 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase ALX04_RS13850 c5608bbb7598fe62ca895dbb88b8b8f1 745 SUPERFAMILY SSF140990 437 634 2.09E-68 T 28-03-2018 ALX04_RS13850 c5608bbb7598fe62ca895dbb88b8b8f1 745 Gene3D G3DSA:3.40.50.300 173 364 1.3E-58 T 28-03-2018 ALX04_RS13850 c5608bbb7598fe62ca895dbb88b8b8f1 745 Hamap MF_01458 ATP-dependent zinc metalloprotease FtsH [ftsH]. 7 636 37.002 T 28-03-2018 IPR005936 Peptidase, FtsH GO:0004222|GO:0016020 Reactome: R-HSA-8949664 ALX04_RS13850 c5608bbb7598fe62ca895dbb88b8b8f1 745 Pfam PF01434 Peptidase family M41 417 623 6.7E-79 T 28-03-2018 IPR000642 Peptidase M41 GO:0004222|GO:0005524|GO:0006508 Reactome: R-HSA-8949664 ALX04_RS13850 c5608bbb7598fe62ca895dbb88b8b8f1 745 Pfam PF06480 FtsH Extracellular 13 125 1.3E-14 T 28-03-2018 IPR011546 Peptidase M41, FtsH extracellular GO:0004222|GO:0005524|GO:0008270|GO:0016021 Reactome: R-HSA-8949664 ALX04_RS13850 c5608bbb7598fe62ca895dbb88b8b8f1 745 SMART SM00382 219 358 1.9E-24 T 28-03-2018 IPR003593 AAA+ ATPase domain ALX04_RS13850 c5608bbb7598fe62ca895dbb88b8b8f1 745 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 223 355 1.2E-45 T 28-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 ALX04_RS13850 c5608bbb7598fe62ca895dbb88b8b8f1 745 TIGRFAM TIGR01241 FtsH_fam: ATP-dependent metallopeptidase HflB 133 625 9.4E-230 T 28-03-2018 IPR005936 Peptidase, FtsH GO:0004222|GO:0016020 Reactome: R-HSA-8949664 ALX04_RS13850 c5608bbb7598fe62ca895dbb88b8b8f1 745 Gene3D G3DSA:1.10.8.60 365 445 4.9E-26 T 28-03-2018 ALX04_RS13850 c5608bbb7598fe62ca895dbb88b8b8f1 745 ProSitePatterns PS00674 AAA-protein family signature. 326 344 - T 28-03-2018 IPR003960 ATPase, AAA-type, conserved site GO:0005524 ALX04_RS08175 c605a1c3d4e8b76e64e5283c46d29b13 244 SUPERFAMILY SSF53448 4 227 6.57E-54 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases ALX04_RS08175 c605a1c3d4e8b76e64e5283c46d29b13 244 Gene3D G3DSA:3.90.550.10 2 244 1.2E-50 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases ALX04_RS08175 c605a1c3d4e8b76e64e5283c46d29b13 244 Pfam PF00535 Glycosyl transferase family 2 7 131 6.2E-35 T 28-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 ALX04_RS03905 b5fe4b896c1053da3451b8e9fe92474c 91 PRINTS PR01727 Prokaryotic integration host factor signature 41 56 6.2E-22 T 28-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 ALX04_RS03905 b5fe4b896c1053da3451b8e9fe92474c 91 PRINTS PR01727 Prokaryotic integration host factor signature 75 89 6.2E-22 T 28-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 ALX04_RS03905 b5fe4b896c1053da3451b8e9fe92474c 91 PRINTS PR01727 Prokaryotic integration host factor signature 59 72 6.2E-22 T 28-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 ALX04_RS03905 b5fe4b896c1053da3451b8e9fe92474c 91 Pfam PF00216 Bacterial DNA-binding protein 3 91 9.7E-37 T 28-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 ALX04_RS03905 b5fe4b896c1053da3451b8e9fe92474c 91 SUPERFAMILY SSF47729 3 91 1.77E-34 T 28-03-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 ALX04_RS03905 b5fe4b896c1053da3451b8e9fe92474c 91 ProSitePatterns PS00045 Bacterial histone-like DNA-binding proteins signature. 47 66 - T 28-03-2018 IPR020816 Histone-like DNA-binding protein, conserved site GO:0003677 ALX04_RS03905 b5fe4b896c1053da3451b8e9fe92474c 91 SMART SM00411 2 91 2.4E-50 T 28-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 ALX04_RS03905 b5fe4b896c1053da3451b8e9fe92474c 91 Gene3D G3DSA:4.10.520.10 2 91 1.8E-37 T 28-03-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 ALX04_RS12025 b8e70fb9b71a14b4c9e74e2b13113993 276 TIGRFAM TIGR00268 TIGR00268: TIGR00268 family protein 11 261 1.8E-55 T 28-03-2018 IPR005232 Lactate racemization operon protein LarE ALX04_RS12025 b8e70fb9b71a14b4c9e74e2b13113993 276 SUPERFAMILY SSF52402 14 192 3.09E-28 T 28-03-2018 ALX04_RS12025 b8e70fb9b71a14b4c9e74e2b13113993 276 Gene3D G3DSA:3.40.50.620 2 274 1.2E-22 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold ALX04_RS12025 b8e70fb9b71a14b4c9e74e2b13113993 276 Pfam PF02540 NAD synthase 18 82 5.3E-9 T 28-03-2018 IPR022310 NAD/GMP synthase ALX04_RS12025 b8e70fb9b71a14b4c9e74e2b13113993 276 PIRSF PIRSF006661 1 273 1.2E-98 T 28-03-2018 IPR005232 Lactate racemization operon protein LarE ALX04_RS13535 f9550aaeba787fec4aa52fb5a9cbc936 187 Pfam PF01751 Toprim domain 6 71 5.4E-5 T 28-03-2018 IPR006171 TOPRIM domain ALX04_RS13535 f9550aaeba787fec4aa52fb5a9cbc936 187 SUPERFAMILY SSF110455 2 119 1.05E-35 T 28-03-2018 ALX04_RS13535 f9550aaeba787fec4aa52fb5a9cbc936 187 SMART SM00493 5 78 3.9E-7 T 28-03-2018 IPR006171 TOPRIM domain ALX04_RS13535 f9550aaeba787fec4aa52fb5a9cbc936 187 Pfam PF13331 Domain of unknown function (DUF4093) 94 179 8.1E-27 T 28-03-2018 IPR025156 Ribonuclease M5, C-terminal domain ALX04_RS13535 f9550aaeba787fec4aa52fb5a9cbc936 187 Gene3D G3DSA:3.40.1360.20 1 126 1.4E-22 T 28-03-2018 ALX04_RS13535 f9550aaeba787fec4aa52fb5a9cbc936 187 Hamap MF_01469 Ribonuclease M5 [rnmV]. 3 181 30.03 T 28-03-2018 IPR004466 Ribonuclease M5 GO:0043822 ALX04_RS13535 f9550aaeba787fec4aa52fb5a9cbc936 187 TIGRFAM TIGR00334 5S_RNA_mat_M5: ribonuclease M5 3 179 8.7E-53 T 28-03-2018 IPR004466 Ribonuclease M5 GO:0043822 ALX04_RS09335 e4ab4293cbc1218c4fca697048960fb8 251 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 13 249 3.8E-68 T 28-03-2018 ALX04_RS09335 e4ab4293cbc1218c4fca697048960fb8 251 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 135 143 9.4E-8 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR ALX04_RS09335 e4ab4293cbc1218c4fca697048960fb8 251 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 155 174 9.4E-8 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR ALX04_RS09335 e4ab4293cbc1218c4fca697048960fb8 251 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 80 91 9.4E-8 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR ALX04_RS09335 e4ab4293cbc1218c4fca697048960fb8 251 Gene3D G3DSA:3.40.50.720 47 251 3.6E-60 T 28-03-2018 ALX04_RS09335 e4ab4293cbc1218c4fca697048960fb8 251 Gene3D G3DSA:3.40.50.720 1 46 1.7E-9 T 28-03-2018 ALX04_RS09335 e4ab4293cbc1218c4fca697048960fb8 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 212 232 9.6E-40 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR ALX04_RS09335 e4ab4293cbc1218c4fca697048960fb8 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 129 145 9.6E-40 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR ALX04_RS09335 e4ab4293cbc1218c4fca697048960fb8 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 80 91 9.6E-40 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR ALX04_RS09335 e4ab4293cbc1218c4fca697048960fb8 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 9.6E-40 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR ALX04_RS09335 e4ab4293cbc1218c4fca697048960fb8 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 155 174 9.6E-40 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR ALX04_RS09335 e4ab4293cbc1218c4fca697048960fb8 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 176 193 9.6E-40 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR ALX04_RS09335 e4ab4293cbc1218c4fca697048960fb8 251 SUPERFAMILY SSF51735 6 250 2.46E-76 T 28-03-2018 IPR016040 NAD(P)-binding domain ALX04_RS07665 866da543efc64b0887e02e128c939d1d 167 Gene3D G3DSA:3.90.960.10 1 167 1.1E-34 T 28-03-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 ALX04_RS07665 866da543efc64b0887e02e128c939d1d 167 PIRSF PIRSF006181 8 167 1.2E-52 T 28-03-2018 IPR004369 Prolyl-tRNA editing protein, YbaK/EbsC ALX04_RS07665 866da543efc64b0887e02e128c939d1d 167 Pfam PF04073 Aminoacyl-tRNA editing domain 44 157 4.3E-23 T 28-03-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 ALX04_RS07665 866da543efc64b0887e02e128c939d1d 167 TIGRFAM TIGR00011 YbaK_EbsC: Cys-tRNA(Pro) deacylase 13 166 2.9E-53 T 28-03-2018 IPR004369 Prolyl-tRNA editing protein, YbaK/EbsC ALX04_RS07665 866da543efc64b0887e02e128c939d1d 167 SUPERFAMILY SSF55826 15 165 2.49E-37 T 28-03-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 ALX04_RS04605 2d781da85783bc6bc026526c9aab339e 158 SUPERFAMILY SSF74942 87 158 4.84E-20 T 28-03-2018 IPR028998 Ribosome maturation factor RimP, C-terminal ALX04_RS04605 2d781da85783bc6bc026526c9aab339e 158 Gene3D G3DSA:2.30.30.180 90 156 7.4E-20 T 28-03-2018 IPR028998 Ribosome maturation factor RimP, C-terminal ALX04_RS04605 2d781da85783bc6bc026526c9aab339e 158 Pfam PF17384 RimP C-terminal SH3 domain 89 158 3.1E-17 T 28-03-2018 IPR028998 Ribosome maturation factor RimP, C-terminal ALX04_RS04605 2d781da85783bc6bc026526c9aab339e 158 SUPERFAMILY SSF75420 3 86 3.27E-26 T 28-03-2018 IPR028989 Ribosome maturation factor RimP, N-terminal ALX04_RS04605 2d781da85783bc6bc026526c9aab339e 158 Hamap MF_01077 Ribosome maturation factor RimP [rimP]. 7 158 23.123 T 28-03-2018 IPR003728 Ribosome maturation factor RimP GO:0042274 ALX04_RS04605 2d781da85783bc6bc026526c9aab339e 158 Gene3D G3DSA:3.30.300.70 1 83 1.7E-24 T 28-03-2018 IPR028989 Ribosome maturation factor RimP, N-terminal ALX04_RS04605 2d781da85783bc6bc026526c9aab339e 158 Pfam PF02576 RimP N-terminal domain 14 86 3.0E-26 T 28-03-2018 IPR028989 Ribosome maturation factor RimP, N-terminal ALX04_RS13105 257e7730349634b0aecb2ec63b29188d 319 PRINTS PR00086 L-lactate dehydrogenase signature 28 52 2.8E-29 T 28-03-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 ALX04_RS13105 257e7730349634b0aecb2ec63b29188d 319 PRINTS PR00086 L-lactate dehydrogenase signature 172 185 2.8E-29 T 28-03-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 ALX04_RS13105 257e7730349634b0aecb2ec63b29188d 319 PRINTS PR00086 L-lactate dehydrogenase signature 3 27 2.8E-29 T 28-03-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 ALX04_RS13105 257e7730349634b0aecb2ec63b29188d 319 PRINTS PR00086 L-lactate dehydrogenase signature 118 138 2.8E-29 T 28-03-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 ALX04_RS13105 257e7730349634b0aecb2ec63b29188d 319 PRINTS PR00086 L-lactate dehydrogenase signature 142 160 2.8E-29 T 28-03-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 ALX04_RS13105 257e7730349634b0aecb2ec63b29188d 319 Pfam PF02866 lactate/malate dehydrogenase, alpha/beta C-terminal domain 147 299 4.8E-14 T 28-03-2018 IPR022383 Lactate/malate dehydrogenase, C-terminal GO:0016616|GO:0055114 ALX04_RS13105 257e7730349634b0aecb2ec63b29188d 319 Pfam PF00056 lactate/malate dehydrogenase, NAD binding domain 3 144 4.8E-21 T 28-03-2018 IPR001236 Lactate/malate dehydrogenase, N-terminal GO:0016491|GO:0055114 ALX04_RS13105 257e7730349634b0aecb2ec63b29188d 319 SUPERFAMILY SSF56327 145 300 1.18E-43 T 28-03-2018 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 ALX04_RS13105 257e7730349634b0aecb2ec63b29188d 319 PIRSF PIRSF000102 1 311 7.8E-91 T 28-03-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 ALX04_RS13105 257e7730349634b0aecb2ec63b29188d 319 Gene3D G3DSA:3.40.50.720 5 145 7.5E-22 T 28-03-2018 ALX04_RS13105 257e7730349634b0aecb2ec63b29188d 319 SUPERFAMILY SSF51735 1 146 1.17E-34 T 28-03-2018 IPR016040 NAD(P)-binding domain ALX04_RS13105 257e7730349634b0aecb2ec63b29188d 319 Gene3D G3DSA:3.90.110.10 146 309 4.2E-35 T 28-03-2018 ALX04_RS14390 0be338e6f49877bf4216b1c5cc72f1c7 109 Pfam PF06153 Cyclic-di-AMP receptor 1 109 2.3E-45 T 28-03-2018 IPR010375 Cyclic-di-AMP receptor ALX04_RS14390 0be338e6f49877bf4216b1c5cc72f1c7 109 Gene3D G3DSA:3.30.70.120 1 109 3.0E-16 T 28-03-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal ALX04_RS14390 0be338e6f49877bf4216b1c5cc72f1c7 109 SUPERFAMILY SSF54913 1 107 3.5E-13 T 28-03-2018 IPR011322 Nitrogen regulatory PII-like, alpha/beta ALX04_RS14985 8c8204a20eff7804cc13d400600fa44d 477 Gene3D G3DSA:1.20.1250.20 7 199 1.7E-22 T 28-03-2018 ALX04_RS14985 8c8204a20eff7804cc13d400600fa44d 477 Gene3D G3DSA:1.20.1250.20 260 477 5.6E-23 T 28-03-2018 ALX04_RS14985 8c8204a20eff7804cc13d400600fa44d 477 PRINTS PR01036 Tetracycline resistance protein TetB signature 18 42 1.4E-8 T 28-03-2018 ALX04_RS14985 8c8204a20eff7804cc13d400600fa44d 477 PRINTS PR01036 Tetracycline resistance protein TetB signature 139 163 1.4E-8 T 28-03-2018 ALX04_RS14985 8c8204a20eff7804cc13d400600fa44d 477 PRINTS PR01036 Tetracycline resistance protein TetB signature 303 327 1.4E-8 T 28-03-2018 ALX04_RS14985 8c8204a20eff7804cc13d400600fa44d 477 PRINTS PR01036 Tetracycline resistance protein TetB signature 109 129 1.4E-8 T 28-03-2018 ALX04_RS14985 8c8204a20eff7804cc13d400600fa44d 477 Pfam PF07690 Major Facilitator Superfamily 21 410 2.6E-38 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 ALX04_RS14985 8c8204a20eff7804cc13d400600fa44d 477 SUPERFAMILY SSF103473 249 461 6.67E-50 T 28-03-2018 IPR020846 Major facilitator superfamily domain ALX04_RS14985 8c8204a20eff7804cc13d400600fa44d 477 SUPERFAMILY SSF103473 11 201 6.67E-50 T 28-03-2018 IPR020846 Major facilitator superfamily domain ALX04_RS13930 1fba53ad72b15186c09e54753d0b3ed5 126 SUPERFAMILY SSF47413 1 52 6.19E-11 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 ALX04_RS13930 1fba53ad72b15186c09e54753d0b3ed5 126 Pfam PF01381 Helix-turn-helix 1 46 6.8E-13 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 ALX04_RS13930 1fba53ad72b15186c09e54753d0b3ed5 126 Gene3D G3DSA:1.10.3100.10 1 119 2.3E-15 T 28-03-2018 IPR027910 YdiL-like domain ALX04_RS13930 1fba53ad72b15186c09e54753d0b3ed5 126 SMART SM00530 1 46 8.2E-5 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 ALX04_RS00865 2c8d4dd441440bdf52bfd6ddabaabdae 679 Pfam PF01653 NAD-dependent DNA ligase adenylation domain 12 320 2.3E-117 T 28-03-2018 IPR013839 NAD-dependent DNA ligase, adenylation GO:0003911 ALX04_RS00865 2c8d4dd441440bdf52bfd6ddabaabdae 679 Gene3D G3DSA:2.40.50.140 321 393 7.3E-30 T 28-03-2018 ALX04_RS00865 2c8d4dd441440bdf52bfd6ddabaabdae 679 Gene3D G3DSA:3.40.50.10190 567 677 2.5E-21 T 28-03-2018 IPR001357 BRCT domain ALX04_RS00865 2c8d4dd441440bdf52bfd6ddabaabdae 679 Hamap MF_01588 DNA ligase [ligA]. 11 673 50.106 T 28-03-2018 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 ALX04_RS00865 2c8d4dd441440bdf52bfd6ddabaabdae 679 Gene3D G3DSA:1.10.287.610 4 75 4.4E-24 T 28-03-2018 ALX04_RS00865 2c8d4dd441440bdf52bfd6ddabaabdae 679 SUPERFAMILY SSF56091 8 319 1.51E-116 T 28-03-2018 ALX04_RS00865 2c8d4dd441440bdf52bfd6ddabaabdae 679 Pfam PF03120 NAD-dependent DNA ligase OB-fold domain 325 401 4.5E-33 T 28-03-2018 IPR004150 NAD-dependent DNA ligase, OB-fold GO:0003911|GO:0006260|GO:0006281 ALX04_RS00865 2c8d4dd441440bdf52bfd6ddabaabdae 679 Gene3D G3DSA:3.30.470.30 126 255 6.7E-48 T 28-03-2018 ALX04_RS00865 2c8d4dd441440bdf52bfd6ddabaabdae 679 SUPERFAMILY SSF47781 406 586 2.15E-60 T 28-03-2018 IPR010994 RuvA domain 2-like ALX04_RS00865 2c8d4dd441440bdf52bfd6ddabaabdae 679 TIGRFAM TIGR00575 dnlj: DNA ligase, NAD-dependent 20 669 2.5E-250 T 28-03-2018 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 ALX04_RS00865 2c8d4dd441440bdf52bfd6ddabaabdae 679 Pfam PF00533 BRCA1 C Terminus (BRCT) domain 602 667 1.1E-12 T 28-03-2018 IPR001357 BRCT domain ALX04_RS00865 2c8d4dd441440bdf52bfd6ddabaabdae 679 ProSitePatterns PS01056 NAD-dependent DNA ligase signature 2. 334 349 - T 28-03-2018 IPR033136 NAD-dependent DNA ligase, conserved site ALX04_RS00865 2c8d4dd441440bdf52bfd6ddabaabdae 679 Pfam PF03119 NAD-dependent DNA ligase C4 zinc finger domain 410 436 5.1E-10 T 28-03-2018 IPR004149 Zinc-finger, NAD-dependent DNA ligase C4-type GO:0003911|GO:0006260|GO:0006281 ALX04_RS00865 2c8d4dd441440bdf52bfd6ddabaabdae 679 Pfam PF12826 Helix-hairpin-helix motif 512 575 8.8E-23 T 28-03-2018 ALX04_RS00865 2c8d4dd441440bdf52bfd6ddabaabdae 679 SMART SM00532 12 450 2.0E-253 T 28-03-2018 IPR013840 NAD-dependent DNA ligase, N-terminal GO:0003911 ALX04_RS00865 2c8d4dd441440bdf52bfd6ddabaabdae 679 PIRSF PIRSF001604 5 678 1.6E-242 T 28-03-2018 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 ALX04_RS00865 2c8d4dd441440bdf52bfd6ddabaabdae 679 Gene3D G3DSA:1.10.150.20 434 504 9.1E-25 T 28-03-2018 ALX04_RS00865 2c8d4dd441440bdf52bfd6ddabaabdae 679 SMART SM00292 599 676 1.1E-7 T 28-03-2018 IPR001357 BRCT domain ALX04_RS00865 2c8d4dd441440bdf52bfd6ddabaabdae 679 SUPERFAMILY SSF50249 321 403 4.28E-26 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold ALX04_RS00865 2c8d4dd441440bdf52bfd6ddabaabdae 679 Gene3D G3DSA:1.10.150.20 505 566 2.3E-23 T 28-03-2018 ALX04_RS00865 2c8d4dd441440bdf52bfd6ddabaabdae 679 ProSitePatterns PS01055 NAD-dependent DNA ligase signature 1. 122 151 - T 28-03-2018 IPR018239 NAD-dependent DNA ligase, active site ALX04_RS00865 2c8d4dd441440bdf52bfd6ddabaabdae 679 SUPERFAMILY SSF52113 596 674 3.11E-18 T 28-03-2018 IPR001357 BRCT domain ALX04_RS01700 d5f4e25e2791024ed98e2aaaa87b7c1a 228 SUPERFAMILY SSF51695 4 224 1.41E-57 T 28-03-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 ALX04_RS01700 d5f4e25e2791024ed98e2aaaa87b7c1a 228 Pfam PF03009 Glycerophosphoryl diester phosphodiesterase family 10 218 5.5E-30 T 28-03-2018 IPR030395 Glycerophosphodiester phosphodiesterase domain GO:0006629|GO:0008081 ALX04_RS01700 d5f4e25e2791024ed98e2aaaa87b7c1a 228 Gene3D G3DSA:3.20.20.190 2 228 2.1E-55 T 28-03-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 ALX04_RS14645 bc412ad2e23b93f3a8d9896deddd738b 575 Gene3D G3DSA:3.40.120.10 338 454 2.6E-35 T 28-03-2018 ALX04_RS14645 bc412ad2e23b93f3a8d9896deddd738b 575 SUPERFAMILY SSF53738 209 316 1.41E-20 T 28-03-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 ALX04_RS14645 bc412ad2e23b93f3a8d9896deddd738b 575 Gene3D G3DSA:3.40.120.10 214 337 4.4E-29 T 28-03-2018 ALX04_RS14645 bc412ad2e23b93f3a8d9896deddd738b 575 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 139 153 6.3E-5 T 28-03-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 ALX04_RS14645 bc412ad2e23b93f3a8d9896deddd738b 575 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 298 313 6.3E-5 T 28-03-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 ALX04_RS14645 bc412ad2e23b93f3a8d9896deddd738b 575 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 42 181 1.9E-37 T 28-03-2018 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 ALX04_RS14645 bc412ad2e23b93f3a8d9896deddd738b 575 ProSitePatterns PS00710 Phosphoglucomutase and phosphomannomutase phosphoserine signature. 140 149 - T 28-03-2018 IPR016066 Alpha-D-phosphohexomutase, conserved site GO:0000287 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 ALX04_RS14645 bc412ad2e23b93f3a8d9896deddd738b 575 Gene3D G3DSA:3.30.310.50 469 575 1.2E-21 T 28-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 ALX04_RS14645 bc412ad2e23b93f3a8d9896deddd738b 575 SUPERFAMILY SSF53738 33 238 7.85E-45 T 28-03-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 ALX04_RS14645 bc412ad2e23b93f3a8d9896deddd738b 575 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 496 553 7.8E-11 T 28-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 ALX04_RS14645 bc412ad2e23b93f3a8d9896deddd738b 575 SUPERFAMILY SSF55957 514 574 1.96E-14 T 28-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 ALX04_RS14645 bc412ad2e23b93f3a8d9896deddd738b 575 SUPERFAMILY SSF55957 446 483 1.96E-14 T 28-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 ALX04_RS14645 bc412ad2e23b93f3a8d9896deddd738b 575 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 326 453 2.3E-21 T 28-03-2018 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 ALX04_RS14645 bc412ad2e23b93f3a8d9896deddd738b 575 Gene3D G3DSA:3.40.120.10 13 213 1.2E-52 T 28-03-2018 ALX04_RS14645 bc412ad2e23b93f3a8d9896deddd738b 575 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 211 314 4.3E-23 T 28-03-2018 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 ALX04_RS14645 bc412ad2e23b93f3a8d9896deddd738b 575 SUPERFAMILY SSF53738 306 457 2.2E-31 T 28-03-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 ALX04_RS14605 35d8e5048ae473329fe0f16a0787e399 282 TIGRFAM TIGR00544 lgt: prolipoprotein diacylglyceryl transferase 8 263 8.0E-73 T 28-03-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0009249|GO:0016020|GO:0016757|GO:0042158 ALX04_RS14605 35d8e5048ae473329fe0f16a0787e399 282 ProSitePatterns PS01311 Prolipoprotein diacylglyceryl transferase signature. 136 148 - T 28-03-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0009249|GO:0016020|GO:0016757|GO:0042158 ALX04_RS14605 35d8e5048ae473329fe0f16a0787e399 282 Pfam PF01790 Prolipoprotein diacylglyceryl transferase 10 258 2.0E-75 T 28-03-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0009249|GO:0016020|GO:0016757|GO:0042158 ALX04_RS14605 35d8e5048ae473329fe0f16a0787e399 282 Hamap MF_01147 Prolipoprotein diacylglyceryl transferase [lgt]. 7 263 17.233 T 28-03-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0009249|GO:0016020|GO:0016757|GO:0042158 ALX04_RS12105 4c65273a270507e41665ee67481b4442 912 Gene3D G3DSA:1.20.1110.10 551 904 4.7E-77 T 28-03-2018 ALX04_RS12105 4c65273a270507e41665ee67481b4442 912 Pfam PF00122 E1-E2 ATPase 138 328 7.6E-49 T 28-03-2018 ALX04_RS12105 4c65273a270507e41665ee67481b4442 912 SUPERFAMILY SSF56784 499 743 1.76E-56 T 28-03-2018 IPR023214 HAD-like domain ALX04_RS12105 4c65273a270507e41665ee67481b4442 912 SUPERFAMILY SSF56784 349 366 1.76E-56 T 28-03-2018 IPR023214 HAD-like domain ALX04_RS12105 4c65273a270507e41665ee67481b4442 912 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 350 356 - T 28-03-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 ALX04_RS12105 4c65273a270507e41665ee67481b4442 912 Pfam PF00702 haloacid dehalogenase-like hydrolase 346 658 3.2E-19 T 28-03-2018 ALX04_RS12105 4c65273a270507e41665ee67481b4442 912 SUPERFAMILY SSF81665 26 137 1.57E-108 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 ALX04_RS12105 4c65273a270507e41665ee67481b4442 912 SUPERFAMILY SSF81665 248 342 1.57E-108 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 ALX04_RS12105 4c65273a270507e41665ee67481b4442 912 SUPERFAMILY SSF81665 694 906 1.57E-108 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 ALX04_RS12105 4c65273a270507e41665ee67481b4442 912 SMART SM00831 26 99 2.5E-28 T 28-03-2018 IPR004014 Cation-transporting P-type ATPase, N-terminal Reactome: R-HSA-936837 ALX04_RS12105 4c65273a270507e41665ee67481b4442 912 Pfam PF00689 Cation transporting ATPase, C-terminus 729 900 8.0E-36 T 28-03-2018 IPR006068 Cation-transporting P-type ATPase, C-terminal Reactome: R-HSA-936837 ALX04_RS12105 4c65273a270507e41665ee67481b4442 912 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 502 520 1.4E-15 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 ALX04_RS12105 4c65273a270507e41665ee67481b4442 912 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 616 632 1.4E-15 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 ALX04_RS12105 4c65273a270507e41665ee67481b4442 912 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 644 660 1.4E-15 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 ALX04_RS12105 4c65273a270507e41665ee67481b4442 912 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 676 701 1.4E-15 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 ALX04_RS12105 4c65273a270507e41665ee67481b4442 912 Gene3D G3DSA:2.70.150.10 35 248 9.4E-47 T 28-03-2018 ALX04_RS12105 4c65273a270507e41665ee67481b4442 912 Gene3D G3DSA:3.40.1110.10 312 550 7.5E-35 T 28-03-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 ALX04_RS12105 4c65273a270507e41665ee67481b4442 912 Pfam PF00690 Cation transporter/ATPase, N-terminus 28 93 5.3E-19 T 28-03-2018 IPR004014 Cation-transporting P-type ATPase, N-terminal Reactome: R-HSA-936837 ALX04_RS12105 4c65273a270507e41665ee67481b4442 912 SUPERFAMILY SSF81660 355 547 2.94E-34 T 28-03-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 ALX04_RS12105 4c65273a270507e41665ee67481b4442 912 SUPERFAMILY SSF81653 140 247 1.31E-30 T 28-03-2018 IPR008250 P-type ATPase, A domain Reactome: R-HSA-936837 ALX04_RS12105 4c65273a270507e41665ee67481b4442 912 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 348 362 6.5E-39 T 28-03-2018 ALX04_RS12105 4c65273a270507e41665ee67481b4442 912 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 668 680 6.5E-39 T 28-03-2018 ALX04_RS12105 4c65273a270507e41665ee67481b4442 912 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 543 554 6.5E-39 T 28-03-2018 ALX04_RS12105 4c65273a270507e41665ee67481b4442 912 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 184 198 6.5E-39 T 28-03-2018 ALX04_RS12105 4c65273a270507e41665ee67481b4442 912 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 565 575 6.5E-39 T 28-03-2018 ALX04_RS12105 4c65273a270507e41665ee67481b4442 912 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 644 663 6.5E-39 T 28-03-2018 ALX04_RS12105 4c65273a270507e41665ee67481b4442 912 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 107 369 1.0E-35 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 ALX04_RS12105 4c65273a270507e41665ee67481b4442 912 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 616 725 3.6E-30 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 ALX04_RS00210 87424c97bdbe4273267a6bd103914be1 492 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 17 425 6.2E-112 T 28-03-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 ALX04_RS00210 87424c97bdbe4273267a6bd103914be1 492 SUPERFAMILY SSF103473 11 200 1.7E-68 T 28-03-2018 IPR020846 Major facilitator superfamily domain ALX04_RS00210 87424c97bdbe4273267a6bd103914be1 492 SUPERFAMILY SSF103473 251 423 1.7E-68 T 28-03-2018 IPR020846 Major facilitator superfamily domain ALX04_RS00210 87424c97bdbe4273267a6bd103914be1 492 SUPERFAMILY SSF103473 452 476 1.7E-68 T 28-03-2018 IPR020846 Major facilitator superfamily domain ALX04_RS00210 87424c97bdbe4273267a6bd103914be1 492 PRINTS PR01036 Tetracycline resistance protein TetB signature 111 131 2.9E-9 T 28-03-2018 ALX04_RS00210 87424c97bdbe4273267a6bd103914be1 492 PRINTS PR01036 Tetracycline resistance protein TetB signature 141 165 2.9E-9 T 28-03-2018 ALX04_RS00210 87424c97bdbe4273267a6bd103914be1 492 PRINTS PR01036 Tetracycline resistance protein TetB signature 20 44 2.9E-9 T 28-03-2018 ALX04_RS00210 87424c97bdbe4273267a6bd103914be1 492 PRINTS PR01036 Tetracycline resistance protein TetB signature 340 360 2.9E-9 T 28-03-2018 ALX04_RS00210 87424c97bdbe4273267a6bd103914be1 492 PRINTS PR01036 Tetracycline resistance protein TetB signature 403 422 2.9E-9 T 28-03-2018 ALX04_RS00210 87424c97bdbe4273267a6bd103914be1 492 Gene3D G3DSA:1.20.1250.20 13 201 3.3E-34 T 28-03-2018 ALX04_RS00210 87424c97bdbe4273267a6bd103914be1 492 Pfam PF07690 Major Facilitator Superfamily 21 412 2.1E-53 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 ALX04_RS00210 87424c97bdbe4273267a6bd103914be1 492 Gene3D G3DSA:1.20.1250.20 262 491 7.6E-32 T 28-03-2018 ALX04_RS01265 b85fed246da22f52ac0eb13ba837f487 267 Pfam PF02631 RecX family 84 204 2.0E-31 T 28-03-2018 IPR003783 Regulatory protein RecX GO:0006282 ALX04_RS01265 b85fed246da22f52ac0eb13ba837f487 267 Gene3D G3DSA:1.10.10.10 43 107 2.4E-14 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS01265 b85fed246da22f52ac0eb13ba837f487 267 Gene3D G3DSA:1.10.10.10 109 151 3.3E-12 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS01265 b85fed246da22f52ac0eb13ba837f487 267 Gene3D G3DSA:1.10.10.10 214 264 2.0E-4 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS01265 b85fed246da22f52ac0eb13ba837f487 267 Gene3D G3DSA:1.10.10.10 159 207 5.2E-7 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS01265 b85fed246da22f52ac0eb13ba837f487 267 Hamap MF_01114 Regulatory protein RecX [recX]. 42 210 18.116 T 28-03-2018 IPR003783 Regulatory protein RecX GO:0006282 ALX04_RS00135 89606d6c2932c575c2dd31bab2fb66f6 466 SUPERFAMILY SSF103473 7 441 1.05E-32 T 28-03-2018 IPR020846 Major facilitator superfamily domain ALX04_RS00135 89606d6c2932c575c2dd31bab2fb66f6 466 Pfam PF13347 MFS/sugar transport protein 12 440 1.3E-82 T 28-03-2018 ALX04_RS00135 89606d6c2932c575c2dd31bab2fb66f6 466 Gene3D G3DSA:1.20.1250.20 224 453 2.1E-18 T 28-03-2018 ALX04_RS00135 89606d6c2932c575c2dd31bab2fb66f6 466 Gene3D G3DSA:1.20.1250.20 3 223 1.8E-13 T 28-03-2018 ALX04_RS00135 89606d6c2932c575c2dd31bab2fb66f6 466 TIGRFAM TIGR00792 gph: sugar (Glycoside-Pentoside-Hexuronide) transporter 10 444 2.2E-96 T 28-03-2018 IPR001927 Sodium:galactoside symporter GO:0005215|GO:0006814|GO:0016020 ALX04_RS10885 8395ede439a4d9d492bedfc01f5965f5 450 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 234 248 3.5E-15 T 28-03-2018 ALX04_RS10885 8395ede439a4d9d492bedfc01f5965f5 450 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 274 281 3.5E-15 T 28-03-2018 ALX04_RS10885 8395ede439a4d9d492bedfc01f5965f5 450 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 435 450 3.5E-15 T 28-03-2018 ALX04_RS10885 8395ede439a4d9d492bedfc01f5965f5 450 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 149 174 3.5E-15 T 28-03-2018 ALX04_RS10885 8395ede439a4d9d492bedfc01f5965f5 450 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 2 24 3.5E-15 T 28-03-2018 ALX04_RS10885 8395ede439a4d9d492bedfc01f5965f5 450 SUPERFAMILY SSF51905 1 312 1.59E-45 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ALX04_RS10885 8395ede439a4d9d492bedfc01f5965f5 450 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 1 304 9.6E-62 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ALX04_RS10885 8395ede439a4d9d492bedfc01f5965f5 450 Gene3D G3DSA:3.50.50.60 121 251 2.5E-30 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ALX04_RS10885 8395ede439a4d9d492bedfc01f5965f5 450 Gene3D G3DSA:3.50.50.60 1 120 1.5E-18 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ALX04_RS10885 8395ede439a4d9d492bedfc01f5965f5 450 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 104 122 2.3E-20 T 28-03-2018 ALX04_RS10885 8395ede439a4d9d492bedfc01f5965f5 450 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 259 281 2.3E-20 T 28-03-2018 ALX04_RS10885 8395ede439a4d9d492bedfc01f5965f5 450 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 149 167 2.3E-20 T 28-03-2018 ALX04_RS10885 8395ede439a4d9d492bedfc01f5965f5 450 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 3 22 2.3E-20 T 28-03-2018 ALX04_RS10885 8395ede439a4d9d492bedfc01f5965f5 450 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 233 249 2.3E-20 T 28-03-2018 ALX04_RS10885 8395ede439a4d9d492bedfc01f5965f5 450 Gene3D G3DSA:3.30.390.30 325 450 2.9E-18 T 28-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 ALX04_RS10885 8395ede439a4d9d492bedfc01f5965f5 450 SUPERFAMILY SSF55424 320 441 3.09E-30 T 28-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 ALX04_RS10885 8395ede439a4d9d492bedfc01f5965f5 450 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 333 426 1.9E-10 T 28-03-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 ALX04_RS10885 8395ede439a4d9d492bedfc01f5965f5 450 Gene3D G3DSA:3.50.50.60 252 324 3.4E-10 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ALX04_RS10690 01330237348b7251667aea21848f7cee 275 TIGRFAM TIGR00753 undec_PP_bacA: undecaprenyl-diphosphatase UppP 7 264 1.2E-71 T 28-03-2018 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 ALX04_RS10690 01330237348b7251667aea21848f7cee 275 Hamap MF_01006 Undecaprenyl-diphosphatase [uppP]. 2 271 17.902 T 28-03-2018 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 ALX04_RS10690 01330237348b7251667aea21848f7cee 275 Pfam PF02673 Bacitracin resistance protein BacA 7 266 7.7E-86 T 28-03-2018 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 ALX04_RS03380 73d39a058e634678ef260d41271a1940 336 SUPERFAMILY SSF53850 42 304 9.13E-58 T 28-03-2018 ALX04_RS03380 73d39a058e634678ef260d41271a1940 336 Pfam PF13343 Bacterial extracellular solute-binding protein 88 320 4.0E-30 T 28-03-2018 ALX04_RS03380 73d39a058e634678ef260d41271a1940 336 Gene3D G3DSA:3.40.190.10 153 289 1.9E-29 T 28-03-2018 ALX04_RS03380 73d39a058e634678ef260d41271a1940 336 PIRSF PIRSF002825 2 323 8.3E-49 T 28-03-2018 IPR026045 Ferric binding protein ALX04_RS03380 73d39a058e634678ef260d41271a1940 336 Gene3D G3DSA:3.40.190.10 33 152 7.9E-11 T 28-03-2018 ALX04_RS02255 ef585bfcfbecefa5175c2595bbae4e9b 662 TIGRFAM TIGR00437 feoB: ferrous iron transport protein B 8 629 9.8E-178 T 28-03-2018 IPR003373 Ferrous iron transport protein B GO:0005525|GO:0015093|GO:0015684|GO:0016021 ALX04_RS02255 ef585bfcfbecefa5175c2595bbae4e9b 662 SUPERFAMILY SSF52540 2 156 7.8E-31 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase ALX04_RS02255 ef585bfcfbecefa5175c2595bbae4e9b 662 Pfam PF07664 Ferrous iron transport protein B C terminus 451 503 3.8E-13 T 28-03-2018 IPR011640 Ferrous iron transport protein B, C-terminal GO:0015093|GO:0015684|GO:0016021 ALX04_RS02255 ef585bfcfbecefa5175c2595bbae4e9b 662 Pfam PF07670 Nucleoside recognition 347 438 3.1E-12 T 28-03-2018 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: R-HSA-83936 ALX04_RS02255 ef585bfcfbecefa5175c2595bbae4e9b 662 Pfam PF07670 Nucleoside recognition 508 632 3.7E-27 T 28-03-2018 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: R-HSA-83936 ALX04_RS02255 ef585bfcfbecefa5175c2595bbae4e9b 662 Gene3D G3DSA:3.40.50.300 2 167 1.9E-23 T 28-03-2018 ALX04_RS02255 ef585bfcfbecefa5175c2595bbae4e9b 662 Pfam PF02421 Ferrous iron transport protein B 3 153 5.5E-56 T 28-03-2018 IPR030389 FeoB-type guanine nucleotide-binding (G) domain GO:0005525 ALX04_RS02965 c87df515f7cc68f7e5985e9ec56606df 399 Gene3D G3DSA:3.40.50.1100 11 199 2.1E-43 T 28-03-2018 ALX04_RS02965 c87df515f7cc68f7e5985e9ec56606df 399 TIGRFAM TIGR00263 trpB: tryptophan synthase, beta subunit 9 392 2.6E-189 T 28-03-2018 IPR006654 Tryptophan synthase, beta chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 ALX04_RS02965 c87df515f7cc68f7e5985e9ec56606df 399 SUPERFAMILY SSF53686 8 391 3.8E-138 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme ALX04_RS02965 c87df515f7cc68f7e5985e9ec56606df 399 Hamap MF_00133 Tryptophan synthase beta chain [trpB]. 4 393 49.873 T 28-03-2018 IPR023026 Tryptophan synthase beta chain/beta chain-like GO:0000162|GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 ALX04_RS02965 c87df515f7cc68f7e5985e9ec56606df 399 PIRSF PIRSF001413 1 399 2.1E-169 T 28-03-2018 IPR023026 Tryptophan synthase beta chain/beta chain-like GO:0000162|GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 ALX04_RS02965 c87df515f7cc68f7e5985e9ec56606df 399 ProSitePatterns PS00168 Tryptophan synthase beta chain pyridoxal-phosphate attachment site. 83 97 - T 28-03-2018 IPR006653 Tryptophan synthase, beta chain, conserved site GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 ALX04_RS02965 c87df515f7cc68f7e5985e9ec56606df 399 Gene3D G3DSA:3.40.50.1100 200 396 3.1E-38 T 28-03-2018 ALX04_RS02965 c87df515f7cc68f7e5985e9ec56606df 399 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 55 380 5.9E-45 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme ALX04_RS05490 420bd39a6131eb68735ac16c0b3b78f5 232 TIGRFAM TIGR03544 DivI1A_domain: DivIVA domain 3 36 5.5E-16 T 28-03-2018 IPR019933 DivIVA domain ALX04_RS05490 420bd39a6131eb68735ac16c0b3b78f5 232 Pfam PF05103 DivIVA protein 3 144 1.3E-42 T 28-03-2018 IPR007793 DivIVA family ALX04_RS05490 420bd39a6131eb68735ac16c0b3b78f5 232 Gene3D G3DSA:1.20.5.620 94 147 3.0E-5 T 28-03-2018 IPR028987 F-type ATP synthase subunit B-like, membrane domain ALX04_RS12805 6782d1cf1f3f36a22f9e4b98818b4786 234 Pfam PF00486 Transcriptional regulatory protein, C terminal 150 225 8.3E-26 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 ALX04_RS12805 6782d1cf1f3f36a22f9e4b98818b4786 234 SMART SM00862 150 225 1.6E-25 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 ALX04_RS12805 6782d1cf1f3f36a22f9e4b98818b4786 234 Gene3D G3DSA:1.10.10.10 122 232 3.7E-33 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS12805 6782d1cf1f3f36a22f9e4b98818b4786 234 SUPERFAMILY SSF46894 127 226 7.37E-30 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 ALX04_RS12805 6782d1cf1f3f36a22f9e4b98818b4786 234 Gene3D G3DSA:3.40.50.2300 1 121 7.1E-32 T 28-03-2018 ALX04_RS12805 6782d1cf1f3f36a22f9e4b98818b4786 234 Pfam PF00072 Response regulator receiver domain 5 116 6.8E-26 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 ALX04_RS12805 6782d1cf1f3f36a22f9e4b98818b4786 234 SUPERFAMILY SSF52172 3 135 1.39E-36 T 28-03-2018 IPR011006 CheY-like superfamily ALX04_RS12805 6782d1cf1f3f36a22f9e4b98818b4786 234 SMART SM00448 3 115 1.2E-38 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 ALX04_RS07815 fdf6f15221568034db13a323de11215b 305 Hamap MF_00224 Dihydroorotate dehydrogenase [pyrD]. 4 303 38.635 T 28-03-2018 IPR024920 Dihydroorotate dehydrogenase, class 1 GO:0004152|GO:0005737|GO:0006221 ALX04_RS07815 fdf6f15221568034db13a323de11215b 305 SUPERFAMILY SSF51395 3 300 5.0E-78 T 28-03-2018 ALX04_RS07815 fdf6f15221568034db13a323de11215b 305 TIGRFAM TIGR01037 pyrD_sub1_fam: dihydroorotate dehydrogenase family protein 4 300 8.1E-102 T 28-03-2018 IPR005720 Dihydroorotate dehydrogenase domain GO:0005737|GO:0016627|GO:0055114 ALX04_RS07815 fdf6f15221568034db13a323de11215b 305 Pfam PF01180 Dihydroorotate dehydrogenase 4 288 2.3E-79 T 28-03-2018 IPR005720 Dihydroorotate dehydrogenase domain GO:0005737|GO:0016627|GO:0055114 ALX04_RS07815 fdf6f15221568034db13a323de11215b 305 ProSitePatterns PS00911 Dihydroorotate dehydrogenase signature 1. 40 59 - T 28-03-2018 IPR001295 Dihydroorotate dehydrogenase, conserved site GO:0004152|GO:0006207|GO:0055114 Reactome: R-HSA-500753 ALX04_RS07815 fdf6f15221568034db13a323de11215b 305 Gene3D G3DSA:3.20.20.70 1 303 5.9E-57 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 ALX04_RS07815 fdf6f15221568034db13a323de11215b 305 ProSitePatterns PS00912 Dihydroorotate dehydrogenase signature 2. 241 261 - T 28-03-2018 IPR001295 Dihydroorotate dehydrogenase, conserved site GO:0004152|GO:0006207|GO:0055114 Reactome: R-HSA-500753 ALX04_RS07815 fdf6f15221568034db13a323de11215b 305 PIRSF PIRSF000164 1 301 5.7E-79 T 28-03-2018 IPR012135 Dihydroorotate dehydrogenase, class 1/ 2 GO:0004152|GO:0006222|GO:0055114 ALX04_RS06535 ecfd1000209fac5824a98ec4592fbeb3 130 TIGRFAM TIGR01655 yxeA_fam: conserved hypothetical protein 3 126 4.8E-15 T 28-03-2018 IPR006542 Protein of unknown function DUF1093 ALX04_RS06535 ecfd1000209fac5824a98ec4592fbeb3 130 Pfam PF06486 Protein of unknown function (DUF1093) 44 118 2.2E-16 T 28-03-2018 IPR006542 Protein of unknown function DUF1093 ALX04_RS06535 ecfd1000209fac5824a98ec4592fbeb3 130 SUPERFAMILY SSF159121 43 129 4.05E-19 T 28-03-2018 IPR006542 Protein of unknown function DUF1093 ALX04_RS15260 69e5fce7af514c883fb0d5e09541a610 352 ProSitePatterns PS00893 Nudix box signature. 241 262 - T 28-03-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 ALX04_RS15260 69e5fce7af514c883fb0d5e09541a610 352 Gene3D G3DSA:3.90.79.10 187 349 1.3E-17 T 28-03-2018 ALX04_RS15260 69e5fce7af514c883fb0d5e09541a610 352 Pfam PF04229 GrpB protein 38 186 4.2E-24 T 28-03-2018 IPR007344 GrpB/Dephospho-CoA kinase ALX04_RS15260 69e5fce7af514c883fb0d5e09541a610 352 SUPERFAMILY SSF55811 210 332 4.2E-20 T 28-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 ALX04_RS15260 69e5fce7af514c883fb0d5e09541a610 352 Pfam PF00293 NUDIX domain 213 327 4.3E-12 T 28-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 ALX04_RS15260 69e5fce7af514c883fb0d5e09541a610 352 Gene3D G3DSA:3.30.460.10 34 186 2.5E-26 T 28-03-2018 ALX04_RS15260 69e5fce7af514c883fb0d5e09541a610 352 SUPERFAMILY SSF81301 41 192 2.62E-25 T 28-03-2018 ALX04_RS04095 19c1707125c4354650a26cf7b5d805ea 149 SUPERFAMILY SSF46785 3 129 3.56E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS04095 19c1707125c4354650a26cf7b5d805ea 149 SMART SM00347 22 127 0.0099 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 ALX04_RS04095 19c1707125c4354650a26cf7b5d805ea 149 Pfam PF12802 MarR family 27 88 1.2E-9 T 28-03-2018 ALX04_RS04095 19c1707125c4354650a26cf7b5d805ea 149 Gene3D G3DSA:1.10.10.10 1 140 4.4E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS04100 38aa51036ec65b04c895f3e2ade254d8 381 SUPERFAMILY SSF55031 177 290 2.39E-19 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain ALX04_RS04100 38aa51036ec65b04c895f3e2ade254d8 381 Gene3D G3DSA:3.40.630.10 3 263 7.9E-60 T 28-03-2018 ALX04_RS04100 38aa51036ec65b04c895f3e2ade254d8 381 Pfam PF07687 Peptidase dimerisation domain 175 277 1.9E-19 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain ALX04_RS04100 38aa51036ec65b04c895f3e2ade254d8 381 Gene3D G3DSA:3.40.630.10 264 381 2.4E-4 T 28-03-2018 ALX04_RS04100 38aa51036ec65b04c895f3e2ade254d8 381 Pfam PF01546 Peptidase family M20/M25/M40 69 375 2.8E-33 T 28-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 ALX04_RS04100 38aa51036ec65b04c895f3e2ade254d8 381 TIGRFAM TIGR01910 DapE-ArgE: peptidase, ArgE/DapE family 11 370 2.4E-123 T 28-03-2018 IPR010182 N-formyl-4-amino-5-aminomethyl-2-methylpyrimidine deformylase/Succinyl-diaminopimelate desuccinylase ALX04_RS04100 38aa51036ec65b04c895f3e2ade254d8 381 SUPERFAMILY SSF53187 7 176 1.03E-56 T 28-03-2018 ALX04_RS04100 38aa51036ec65b04c895f3e2ade254d8 381 SUPERFAMILY SSF53187 294 378 1.03E-56 T 28-03-2018 ALX04_RS04100 38aa51036ec65b04c895f3e2ade254d8 381 ProSitePatterns PS00758 ArgE / dapE / ACY1 / CPG2 / yscS family signature 1. 67 76 - T 28-03-2018 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 ALX04_RS05390 1fbd376e1306d357d84ca81841da57c4 849 Pfam PF13604 AAA domain 348 542 2.3E-47 T 28-03-2018 ALX04_RS05390 1fbd376e1306d357d84ca81841da57c4 849 Gene3D G3DSA:1.10.150.280 108 218 2.1E-6 T 28-03-2018 ALX04_RS05390 1fbd376e1306d357d84ca81841da57c4 849 SMART SM00382 361 547 0.0024 T 28-03-2018 IPR003593 AAA+ ATPase domain ALX04_RS05390 1fbd376e1306d357d84ca81841da57c4 849 Pfam PF14490 Helix-hairpin-helix containing domain 164 253 2.0E-26 T 28-03-2018 IPR029493 RecD helicase-like helix-hairpin-helix domain ALX04_RS05390 1fbd376e1306d357d84ca81841da57c4 849 TIGRFAM TIGR01448 recD_rel: helicase, RecD/TraA family 23 758 8.8E-241 T 28-03-2018 IPR006345 DNA helicase, RecD-like GO:0003677|GO:0032508|GO:0043141 ALX04_RS05390 1fbd376e1306d357d84ca81841da57c4 849 Hamap MF_01488 ATP-dependent RecD-like DNA helicase [recD2]. 19 761 28.251 T 28-03-2018 IPR006345 DNA helicase, RecD-like GO:0003677|GO:0032508|GO:0043141 ALX04_RS05390 1fbd376e1306d357d84ca81841da57c4 849 Gene3D G3DSA:3.40.50.300 529 746 5.7E-31 T 28-03-2018 ALX04_RS05390 1fbd376e1306d357d84ca81841da57c4 849 Gene3D G3DSA:1.10.8.50 219 251 0.14 T 28-03-2018 ALX04_RS05390 1fbd376e1306d357d84ca81841da57c4 849 SUPERFAMILY SSF52540 345 738 5.24E-59 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase ALX04_RS05390 1fbd376e1306d357d84ca81841da57c4 849 Pfam PF13538 UvrD-like helicase C-terminal domain 686 732 6.6E-16 T 28-03-2018 IPR027785 UvrD-like helicase C-terminal domain ALX04_RS05390 1fbd376e1306d357d84ca81841da57c4 849 Gene3D G3DSA:3.40.50.300 304 528 1.6E-37 T 28-03-2018 ALX04_RS04585 b8897ede1f4a7169ed918345d5ba98cd 858 SUPERFAMILY SSF50447 532 614 3.93E-24 T 28-03-2018 IPR009000 Translation protein, beta-barrel domain ALX04_RS04585 b8897ede1f4a7169ed918345d5ba98cd 858 Pfam PF00009 Elongation factor Tu GTP binding domain 364 519 1.2E-33 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 ALX04_RS04585 b8897ede1f4a7169ed918345d5ba98cd 858 Hamap MF_00100_B Translation initiation factor IF-2 [infB]. 3 857 16.957 T 28-03-2018 IPR000178 Translation initiation factor aIF-2, bacterial-like GO:0003743|GO:0005525|GO:0005622|GO:0006413 Reactome: R-HSA-5368286 ALX04_RS04585 b8897ede1f4a7169ed918345d5ba98cd 858 Pfam PF04760 Translation initiation factor IF-2, N-terminal region 286 330 2.8E-10 T 28-03-2018 IPR006847 Translation initiation factor IF-2, N-terminal ALX04_RS04585 b8897ede1f4a7169ed918345d5ba98cd 858 Pfam PF04760 Translation initiation factor IF-2, N-terminal region 1 46 6.9E-16 T 28-03-2018 IPR006847 Translation initiation factor IF-2, N-terminal ALX04_RS04585 b8897ede1f4a7169ed918345d5ba98cd 858 Gene3D G3DSA:2.40.30.10 760 857 2.6E-28 T 28-03-2018 ALX04_RS04585 b8897ede1f4a7169ed918345d5ba98cd 858 TIGRFAM TIGR00487 IF-2: translation initiation factor IF-2 274 855 4.8E-254 T 28-03-2018 IPR000178 Translation initiation factor aIF-2, bacterial-like GO:0003743|GO:0005525|GO:0005622|GO:0006413 Reactome: R-HSA-5368286 ALX04_RS04585 b8897ede1f4a7169ed918345d5ba98cd 858 Pfam PF11987 Translation-initiation factor 2 645 749 1.9E-37 T 28-03-2018 IPR023115 Translation initiation factor IF- 2, domain 3 ALX04_RS04585 b8897ede1f4a7169ed918345d5ba98cd 858 Gene3D G3DSA:3.40.50.300 354 527 4.5E-39 T 28-03-2018 ALX04_RS04585 b8897ede1f4a7169ed918345d5ba98cd 858 Gene3D G3DSA:3.40.50.10050 657 738 3.2E-28 T 28-03-2018 IPR023115 Translation initiation factor IF- 2, domain 3 ALX04_RS04585 b8897ede1f4a7169ed918345d5ba98cd 858 Gene3D G3DSA:2.40.30.10 528 623 7.1E-11 T 28-03-2018 ALX04_RS04585 b8897ede1f4a7169ed918345d5ba98cd 858 SUPERFAMILY SSF50447 760 855 1.29E-30 T 28-03-2018 IPR009000 Translation protein, beta-barrel domain ALX04_RS04585 b8897ede1f4a7169ed918345d5ba98cd 858 SUPERFAMILY SSF52540 352 529 8.27E-53 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase ALX04_RS04585 b8897ede1f4a7169ed918345d5ba98cd 858 Gene3D G3DSA:3.30.56.50 284 324 8.6E-7 T 28-03-2018 ALX04_RS04585 b8897ede1f4a7169ed918345d5ba98cd 858 Gene3D G3DSA:3.30.56.50 4 46 4.8E-15 T 28-03-2018 ALX04_RS04585 b8897ede1f4a7169ed918345d5ba98cd 858 SUPERFAMILY SSF52156 636 766 4.18E-39 T 28-03-2018 IPR023115 Translation initiation factor IF- 2, domain 3 ALX04_RS04585 b8897ede1f4a7169ed918345d5ba98cd 858 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 363 518 6.5E-37 T 28-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 ALX04_RS00410 78db4d63dfc87bafea751ec9608c772e 217 Gene3D G3DSA:3.30.300.20 17 106 1.9E-29 T 28-03-2018 IPR015946 K homology domain-like, alpha/beta ALX04_RS00410 78db4d63dfc87bafea751ec9608c772e 217 SUPERFAMILY SSF54814 2 105 6.54E-37 T 28-03-2018 IPR009019 K homology domain, prokaryotic type GO:0003723 ALX04_RS00410 78db4d63dfc87bafea751ec9608c772e 217 Pfam PF00189 Ribosomal protein S3, C-terminal domain 119 201 1.4E-35 T 28-03-2018 IPR001351 Ribosomal protein S3, C-terminal GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 ALX04_RS00410 78db4d63dfc87bafea751ec9608c772e 217 Pfam PF07650 KH domain 38 109 2.4E-21 T 28-03-2018 IPR004044 K Homology domain, type 2 GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 ALX04_RS00410 78db4d63dfc87bafea751ec9608c772e 217 SUPERFAMILY SSF54821 106 205 3.79E-36 T 28-03-2018 IPR001351 Ribosomal protein S3, C-terminal GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 ALX04_RS00410 78db4d63dfc87bafea751ec9608c772e 217 ProSitePatterns PS00548 Ribosomal protein S3 signature. 162 196 - T 28-03-2018 IPR018280 Ribosomal protein S3, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 ALX04_RS00410 78db4d63dfc87bafea751ec9608c772e 217 SMART SM00322 59 124 1.5E-9 T 28-03-2018 IPR004087 K Homology domain GO:0003676 ALX04_RS00410 78db4d63dfc87bafea751ec9608c772e 217 Gene3D G3DSA:3.30.1140.32 107 206 5.4E-35 T 28-03-2018 ALX04_RS00410 78db4d63dfc87bafea751ec9608c772e 217 TIGRFAM TIGR01009 rpsC_bact: ribosomal protein uS3 1 208 1.2E-89 T 28-03-2018 IPR005704 Ribosomal protein S3, bacterial GO:0003735|GO:0006412|GO:0015935 ALX04_RS00410 78db4d63dfc87bafea751ec9608c772e 217 Hamap MF_01309_B 30S ribosomal protein S3 [rpsC]. 1 205 37.023 T 28-03-2018 IPR005704 Ribosomal protein S3, bacterial GO:0003735|GO:0006412|GO:0015935 ALX04_RS12945 8b92a797954ca8008a5960f3ced18bf3 400 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 4 23 1.7E-8 T 28-03-2018 ALX04_RS12945 8b92a797954ca8008a5960f3ced18bf3 400 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 274 296 1.7E-8 T 28-03-2018 ALX04_RS12945 8b92a797954ca8008a5960f3ced18bf3 400 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 153 171 1.7E-8 T 28-03-2018 ALX04_RS12945 8b92a797954ca8008a5960f3ced18bf3 400 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 97 115 1.7E-8 T 28-03-2018 ALX04_RS12945 8b92a797954ca8008a5960f3ced18bf3 400 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 5 318 7.8E-44 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ALX04_RS12945 8b92a797954ca8008a5960f3ced18bf3 400 SUPERFAMILY SSF51905 4 201 7.92E-28 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ALX04_RS12945 8b92a797954ca8008a5960f3ced18bf3 400 SUPERFAMILY SSF51905 147 328 1.25E-18 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ALX04_RS12945 8b92a797954ca8008a5960f3ced18bf3 400 Gene3D G3DSA:3.40.50.720 2 140 1.8E-11 T 28-03-2018 ALX04_RS12945 8b92a797954ca8008a5960f3ced18bf3 400 Gene3D G3DSA:3.50.50.60 142 369 1.3E-25 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ALX04_RS07330 d56c599fc7ff467fd3ea09af7fd45e0e 302 Gene3D G3DSA:1.20.58.340 98 234 5.5E-7 T 28-03-2018 ALX04_RS07330 d56c599fc7ff467fd3ea09af7fd45e0e 302 Pfam PF01544 CorA-like Mg2+ transporter protein 9 297 1.6E-49 T 28-03-2018 IPR002523 Mg2+ transporter protein, CorA-like/Zinc transport protein ZntB GO:0016020|GO:0030001|GO:0046873|GO:0055085 ALX04_RS07330 d56c599fc7ff467fd3ea09af7fd45e0e 302 Gene3D G3DSA:3.30.460.20 3 97 4.7E-9 T 28-03-2018 ALX04_RS07330 d56c599fc7ff467fd3ea09af7fd45e0e 302 SUPERFAMILY SSF143865 8 236 1.31E-31 T 28-03-2018 ALX04_RS07330 d56c599fc7ff467fd3ea09af7fd45e0e 302 SUPERFAMILY SSF144083 238 297 3.79E-13 T 28-03-2018 ALX04_RS07330 d56c599fc7ff467fd3ea09af7fd45e0e 302 Gene3D G3DSA:1.20.58.340 235 300 1.4E-8 T 28-03-2018 ALX04_RS02960 53e229e87e0b47cbbee31d0f5af4d8f9 208 Gene3D G3DSA:3.20.20.70 1 195 8.0E-55 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 ALX04_RS02960 53e229e87e0b47cbbee31d0f5af4d8f9 208 Hamap MF_00135 N-(5'-phosphoribosyl)anthranilate isomerase [trpF]. 2 195 30.833 T 28-03-2018 IPR001240 N-(5'phosphoribosyl) anthranilate isomerase (PRAI) GO:0004640|GO:0006568 KEGG: 00400+5.3.1.24 ALX04_RS02960 53e229e87e0b47cbbee31d0f5af4d8f9 208 SUPERFAMILY SSF51366 3 192 6.59E-44 T 28-03-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 ALX04_RS02960 53e229e87e0b47cbbee31d0f5af4d8f9 208 Pfam PF00697 N-(5'phosphoribosyl)anthranilate (PRA) isomerase 4 190 1.7E-43 T 28-03-2018 IPR001240 N-(5'phosphoribosyl) anthranilate isomerase (PRAI) GO:0004640|GO:0006568 KEGG: 00400+5.3.1.24 ALX04_RS00490 c02e2134310e7b00223ff0f9ac4700a3 72 TIGRFAM TIGR00008 infA: translation initiation factor IF-1 3 70 8.4E-39 T 28-03-2018 IPR004368 Translation initiation factor IF-1 GO:0003743|GO:0006413 ALX04_RS00490 c02e2134310e7b00223ff0f9ac4700a3 72 Gene3D G3DSA:2.40.50.140 1 72 2.5E-37 T 28-03-2018 ALX04_RS00490 c02e2134310e7b00223ff0f9ac4700a3 72 Pfam PF01176 Translation initiation factor 1A / IF-1 7 70 1.0E-27 T 28-03-2018 IPR006196 RNA-binding domain, S1, IF1 type GO:0003723|GO:0003743|GO:0006413 ALX04_RS00490 c02e2134310e7b00223ff0f9ac4700a3 72 SMART SM00316 4 72 7.0E-7 T 28-03-2018 IPR022967 RNA-binding domain, S1 ALX04_RS00490 c02e2134310e7b00223ff0f9ac4700a3 72 Hamap MF_00075 Translation initiation factor IF-1 [infA]. 1 72 27.773 T 28-03-2018 IPR004368 Translation initiation factor IF-1 GO:0003743|GO:0006413 ALX04_RS00490 c02e2134310e7b00223ff0f9ac4700a3 72 SUPERFAMILY SSF50249 1 71 4.41E-28 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold ALX04_RS13790 c5b9b6d2be65b7603be6304e230904e8 168 PIRSF PIRSF031501 1 167 3.3E-52 T 28-03-2018 IPR010387 Queuosine precursor transporter QueT GO:0005886 ALX04_RS13790 c5b9b6d2be65b7603be6304e230904e8 168 Pfam PF06177 QueT transporter 11 158 7.4E-27 T 28-03-2018 IPR010387 Queuosine precursor transporter QueT GO:0005886 ALX04_RS04135 42a802ac1e583c0f43a166cc10941ed8 559 Gene3D G3DSA:1.25.40.10 7 451 4.2E-4 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 ALX04_RS04015 5bee48e6ce0e492c423a8fff2256edb1 412 SUPERFAMILY SSF53187 326 407 6.54E-74 T 28-03-2018 ALX04_RS04015 5bee48e6ce0e492c423a8fff2256edb1 412 SUPERFAMILY SSF53187 5 214 6.54E-74 T 28-03-2018 ALX04_RS04015 5bee48e6ce0e492c423a8fff2256edb1 412 TIGRFAM TIGR01882 peptidase-T: peptidase T 3 410 8.5E-196 T 28-03-2018 IPR010161 Peptidase M20B, tripeptide aminopeptidase GO:0005737|GO:0006518|GO:0008270|GO:0045148 ALX04_RS04015 5bee48e6ce0e492c423a8fff2256edb1 412 SUPERFAMILY SSF55031 213 324 1.78E-39 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain ALX04_RS04015 5bee48e6ce0e492c423a8fff2256edb1 412 Gene3D G3DSA:3.40.630.10 2 411 1.0E-46 T 28-03-2018 ALX04_RS04015 5bee48e6ce0e492c423a8fff2256edb1 412 Hamap MF_00550 Peptidase T [pepT]. 4 408 55.067 T 28-03-2018 IPR010161 Peptidase M20B, tripeptide aminopeptidase GO:0005737|GO:0006518|GO:0008270|GO:0045148 ALX04_RS04015 5bee48e6ce0e492c423a8fff2256edb1 412 Pfam PF01546 Peptidase family M20/M25/M40 143 406 1.9E-12 T 28-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 ALX04_RS04015 5bee48e6ce0e492c423a8fff2256edb1 412 Pfam PF07687 Peptidase dimerisation domain 211 306 9.4E-10 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain ALX04_RS04015 5bee48e6ce0e492c423a8fff2256edb1 412 ProSitePatterns PS00758 ArgE / dapE / ACY1 / CPG2 / yscS family signature 1. 77 86 - T 28-03-2018 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 ALX04_RS04015 5bee48e6ce0e492c423a8fff2256edb1 412 ProSitePatterns PS00759 ArgE / dapE / ACY1 / CPG2 / yscS family signature 2. 142 181 - T 28-03-2018 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 ALX04_RS04015 5bee48e6ce0e492c423a8fff2256edb1 412 PIRSF PIRSF037215 2 412 4.4E-188 T 28-03-2018 IPR010161 Peptidase M20B, tripeptide aminopeptidase GO:0005737|GO:0006518|GO:0008270|GO:0045148 ALX04_RS05075 3c7c1d63ca58c5527b258149df91531d 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 7.1E-25 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR ALX04_RS05075 3c7c1d63ca58c5527b258149df91531d 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 156 175 7.1E-25 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR ALX04_RS05075 3c7c1d63ca58c5527b258149df91531d 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 83 94 7.1E-25 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR ALX04_RS05075 3c7c1d63ca58c5527b258149df91531d 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 177 194 7.1E-25 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR ALX04_RS05075 3c7c1d63ca58c5527b258149df91531d 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 130 146 7.1E-25 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR ALX04_RS05075 3c7c1d63ca58c5527b258149df91531d 263 Gene3D G3DSA:3.40.50.720 1 263 3.2E-53 T 28-03-2018 ALX04_RS05075 3c7c1d63ca58c5527b258149df91531d 263 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 83 94 1.9E-10 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR ALX04_RS05075 3c7c1d63ca58c5527b258149df91531d 263 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 156 175 1.9E-10 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR ALX04_RS05075 3c7c1d63ca58c5527b258149df91531d 263 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 136 144 1.9E-10 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR ALX04_RS05075 3c7c1d63ca58c5527b258149df91531d 263 PIRSF PIRSF000126 1 261 8.7E-52 T 28-03-2018 ALX04_RS05075 3c7c1d63ca58c5527b258149df91531d 263 Pfam PF00106 short chain dehydrogenase 7 195 2.8E-50 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR ALX04_RS05075 3c7c1d63ca58c5527b258149df91531d 263 SUPERFAMILY SSF51735 1 254 4.27E-61 T 28-03-2018 IPR016040 NAD(P)-binding domain ALX04_RS05075 3c7c1d63ca58c5527b258149df91531d 263 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 7 192 0.0019 T 28-03-2018 ALX04_RS07830 5379393af27229487642ddb7d3901934 430 Hamap MF_00220_B Dihydroorotase [pyrC]. 2 427 45.25 T 28-03-2018 IPR004722 Dihydroorotase GO:0004151|GO:0006221|GO:0046872 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 ALX04_RS07830 5379393af27229487642ddb7d3901934 430 TIGRFAM TIGR00857 pyrC_multi: dihydroorotase, multifunctional complex type 18 425 1.5E-132 T 28-03-2018 IPR004722 Dihydroorotase GO:0004151|GO:0006221|GO:0046872 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 ALX04_RS07830 5379393af27229487642ddb7d3901934 430 ProSitePatterns PS00482 Dihydroorotase signature 1. 59 67 - T 28-03-2018 IPR002195 Dihydroorotase, conserved site GO:0016812 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 ALX04_RS07830 5379393af27229487642ddb7d3901934 430 Gene3D G3DSA:3.20.20.140 70 409 1.1E-103 T 28-03-2018 ALX04_RS07830 5379393af27229487642ddb7d3901934 430 ProSitePatterns PS00483 Dihydroorotase signature 2. 304 315 - T 28-03-2018 IPR002195 Dihydroorotase, conserved site GO:0016812 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 ALX04_RS07830 5379393af27229487642ddb7d3901934 430 Pfam PF01979 Amidohydrolase family 52 422 8.0E-45 T 28-03-2018 IPR006680 Amidohydrolase-related GO:0016787 ALX04_RS07830 5379393af27229487642ddb7d3901934 430 Gene3D G3DSA:2.30.40.10 1 69 2.6E-20 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 ALX04_RS07830 5379393af27229487642ddb7d3901934 430 SUPERFAMILY SSF51556 56 368 3.41E-104 T 28-03-2018 IPR032466 Metal-dependent hydrolase ALX04_RS07830 5379393af27229487642ddb7d3901934 430 SUPERFAMILY SSF51338 1 55 3.83E-26 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 ALX04_RS07830 5379393af27229487642ddb7d3901934 430 SUPERFAMILY SSF51338 369 426 3.83E-26 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 ALX04_RS14935 70989c4ea8abc11bed11a38abe15a4d6 250 Gene3D G3DSA:3.40.109.10 2 247 1.5E-40 T 28-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 ALX04_RS14935 70989c4ea8abc11bed11a38abe15a4d6 250 PIRSF PIRSF005426 1 247 1.8E-75 T 28-03-2018 IPR016446 Flavin oxidoreductase Frp family GO:0016491|GO:0055114 ALX04_RS14935 70989c4ea8abc11bed11a38abe15a4d6 250 SUPERFAMILY SSF55469 4 245 3.14E-49 T 28-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 ALX04_RS14935 70989c4ea8abc11bed11a38abe15a4d6 250 Pfam PF00881 Nitroreductase family 12 162 2.0E-14 T 28-03-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 ALX04_RS08595 3baf53717aee84e11c03b94551c6d6cf 285 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 166 267 2.9E-14 T 28-03-2018 ALX04_RS08595 3baf53717aee84e11c03b94551c6d6cf 285 Gene3D G3DSA:3.40.50.720 2 269 2.4E-37 T 28-03-2018 ALX04_RS08595 3baf53717aee84e11c03b94551c6d6cf 285 Pfam PF00106 short chain dehydrogenase 7 132 9.5E-16 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR ALX04_RS08595 3baf53717aee84e11c03b94551c6d6cf 285 SUPERFAMILY SSF51735 1 137 2.45E-37 T 28-03-2018 IPR016040 NAD(P)-binding domain ALX04_RS08595 3baf53717aee84e11c03b94551c6d6cf 285 SUPERFAMILY SSF51735 168 270 2.45E-37 T 28-03-2018 IPR016040 NAD(P)-binding domain ALX04_RS08595 3baf53717aee84e11c03b94551c6d6cf 285 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 6 23 9.9E-12 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR ALX04_RS08595 3baf53717aee84e11c03b94551c6d6cf 285 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 78 89 9.9E-12 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR ALX04_RS08595 3baf53717aee84e11c03b94551c6d6cf 285 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 193 210 9.9E-12 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR ALX04_RS08595 3baf53717aee84e11c03b94551c6d6cf 285 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 230 250 9.9E-12 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR ALX04_RS13705 992940c3be0bb9f43e63ab419f72b8bd 462 SUPERFAMILY SSF63418 8 102 3.14E-23 T 28-03-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 ALX04_RS13705 992940c3be0bb9f43e63ab419f72b8bd 462 SUPERFAMILY SSF53244 315 456 7.88E-32 T 28-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 ALX04_RS13705 992940c3be0bb9f43e63ab419f72b8bd 462 Gene3D G3DSA:3.40.1390.10 1 94 1.5E-25 T 28-03-2018 ALX04_RS13705 992940c3be0bb9f43e63ab419f72b8bd 462 Pfam PF08245 Mur ligase middle domain 110 295 1.4E-50 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 ALX04_RS13705 992940c3be0bb9f43e63ab419f72b8bd 462 Gene3D G3DSA:3.90.190.20 314 462 3.3E-35 T 28-03-2018 ALX04_RS13705 992940c3be0bb9f43e63ab419f72b8bd 462 Pfam PF02875 Mur ligase family, glutamate ligase domain 318 399 2.4E-8 T 28-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 ALX04_RS13705 992940c3be0bb9f43e63ab419f72b8bd 462 SUPERFAMILY SSF53623 104 313 1.28E-52 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 ALX04_RS13705 992940c3be0bb9f43e63ab419f72b8bd 462 Gene3D G3DSA:3.40.1190.10 95 311 4.8E-59 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 ALX04_RS13705 992940c3be0bb9f43e63ab419f72b8bd 462 Hamap MF_02019 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [murF]. 3 457 33.094 T 28-03-2018 IPR005863 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase GO:0005524|GO:0005737|GO:0047480|GO:0071555 KEGG: 00300+6.3.2.10|KEGG: 00550+6.3.2.10|MetaCyc: PWY-6386|MetaCyc: PWY-6387 ALX04_RS13705 992940c3be0bb9f43e63ab419f72b8bd 462 Pfam PF01225 Mur ligase family, catalytic domain 26 97 2.6E-8 T 28-03-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 ALX04_RS13705 992940c3be0bb9f43e63ab419f72b8bd 462 TIGRFAM TIGR01143 murF: UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase 31 456 2.5E-119 T 28-03-2018 IPR005863 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase GO:0005524|GO:0005737|GO:0047480|GO:0071555 KEGG: 00300+6.3.2.10|KEGG: 00550+6.3.2.10|MetaCyc: PWY-6386|MetaCyc: PWY-6387 ALX04_RS01860 7c1c1941a35c00973d94f38f0972ea82 618 Gene3D G3DSA:3.20.20.330 1 324 2.2E-79 T 28-03-2018 IPR003726 Homocysteine-binding domain Reactome: R-HSA-1614635 ALX04_RS01860 7c1c1941a35c00973d94f38f0972ea82 618 SUPERFAMILY SSF51730 326 610 5.3E-68 T 28-03-2018 IPR029041 FAD-linked oxidoreductase-like ALX04_RS01860 7c1c1941a35c00973d94f38f0972ea82 618 SUPERFAMILY SSF82282 1 369 2.62E-88 T 28-03-2018 IPR003726 Homocysteine-binding domain Reactome: R-HSA-1614635 ALX04_RS01860 7c1c1941a35c00973d94f38f0972ea82 618 Pfam PF02219 Methylenetetrahydrofolate reductase 326 606 3.5E-32 T 28-03-2018 IPR003171 Methylenetetrahydrofolate reductase GO:0004489|GO:0006555|GO:0055114 KEGG: 00670+1.5.1.20|KEGG: 00720+1.5.1.20|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-196757 ALX04_RS01860 7c1c1941a35c00973d94f38f0972ea82 618 Gene3D G3DSA:3.20.20.220 325 618 1.1E-65 T 28-03-2018 IPR029041 FAD-linked oxidoreductase-like ALX04_RS01860 7c1c1941a35c00973d94f38f0972ea82 618 Pfam PF02574 Homocysteine S-methyltransferase 12 285 7.9E-51 T 28-03-2018 IPR003726 Homocysteine-binding domain Reactome: R-HSA-1614635 ALX04_RS14080 5c4c30d02e397ab8e76f7c0510115042 884 SUPERFAMILY SSF81660 334 515 6.21E-49 T 28-03-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 ALX04_RS14080 5c4c30d02e397ab8e76f7c0510115042 884 SUPERFAMILY SSF56784 466 719 5.03E-58 T 28-03-2018 IPR023214 HAD-like domain ALX04_RS14080 5c4c30d02e397ab8e76f7c0510115042 884 SUPERFAMILY SSF56784 325 345 5.03E-58 T 28-03-2018 IPR023214 HAD-like domain ALX04_RS14080 5c4c30d02e397ab8e76f7c0510115042 884 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 210 360 3.6E-28 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 ALX04_RS14080 5c4c30d02e397ab8e76f7c0510115042 884 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 85 182 7.9E-22 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 ALX04_RS14080 5c4c30d02e397ab8e76f7c0510115042 884 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 587 698 1.6E-34 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 ALX04_RS14080 5c4c30d02e397ab8e76f7c0510115042 884 SUPERFAMILY SSF81665 665 882 1.83E-133 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 ALX04_RS14080 5c4c30d02e397ab8e76f7c0510115042 884 SUPERFAMILY SSF81665 7 116 1.83E-133 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 ALX04_RS14080 5c4c30d02e397ab8e76f7c0510115042 884 SUPERFAMILY SSF81665 227 321 1.83E-133 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 ALX04_RS14080 5c4c30d02e397ab8e76f7c0510115042 884 Pfam PF00702 haloacid dehalogenase-like hydrolase 324 629 1.0E-24 T 28-03-2018 ALX04_RS14080 5c4c30d02e397ab8e76f7c0510115042 884 Pfam PF00690 Cation transporter/ATPase, N-terminus 7 73 1.6E-21 T 28-03-2018 IPR004014 Cation-transporting P-type ATPase, N-terminal Reactome: R-HSA-936837 ALX04_RS14080 5c4c30d02e397ab8e76f7c0510115042 884 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 329 335 - T 28-03-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 ALX04_RS14080 5c4c30d02e397ab8e76f7c0510115042 884 SMART SM00831 5 78 1.1E-26 T 28-03-2018 IPR004014 Cation-transporting P-type ATPase, N-terminal Reactome: R-HSA-936837 ALX04_RS14080 5c4c30d02e397ab8e76f7c0510115042 884 Gene3D G3DSA:3.40.1110.10 290 518 8.9E-52 T 28-03-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 ALX04_RS14080 5c4c30d02e397ab8e76f7c0510115042 884 SUPERFAMILY SSF81653 117 226 1.11E-32 T 28-03-2018 IPR008250 P-type ATPase, A domain Reactome: R-HSA-936837 ALX04_RS14080 5c4c30d02e397ab8e76f7c0510115042 884 Pfam PF00122 E1-E2 ATPase 113 307 6.3E-58 T 28-03-2018 ALX04_RS14080 5c4c30d02e397ab8e76f7c0510115042 884 Gene3D G3DSA:2.70.150.10 14 227 3.6E-51 T 28-03-2018 ALX04_RS14080 5c4c30d02e397ab8e76f7c0510115042 884 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 587 603 1.0E-16 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 ALX04_RS14080 5c4c30d02e397ab8e76f7c0510115042 884 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 615 631 1.0E-16 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 ALX04_RS14080 5c4c30d02e397ab8e76f7c0510115042 884 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 647 672 1.0E-16 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 ALX04_RS14080 5c4c30d02e397ab8e76f7c0510115042 884 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 469 487 1.0E-16 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 ALX04_RS14080 5c4c30d02e397ab8e76f7c0510115042 884 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 327 341 6.9E-39 T 28-03-2018 ALX04_RS14080 5c4c30d02e397ab8e76f7c0510115042 884 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 615 634 6.9E-39 T 28-03-2018 ALX04_RS14080 5c4c30d02e397ab8e76f7c0510115042 884 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 511 522 6.9E-39 T 28-03-2018 ALX04_RS14080 5c4c30d02e397ab8e76f7c0510115042 884 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 533 543 6.9E-39 T 28-03-2018 ALX04_RS14080 5c4c30d02e397ab8e76f7c0510115042 884 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 163 177 6.9E-39 T 28-03-2018 ALX04_RS14080 5c4c30d02e397ab8e76f7c0510115042 884 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 639 651 6.9E-39 T 28-03-2018 ALX04_RS14080 5c4c30d02e397ab8e76f7c0510115042 884 Gene3D G3DSA:1.20.1110.10 540 884 6.2E-97 T 28-03-2018 ALX04_RS14080 5c4c30d02e397ab8e76f7c0510115042 884 Pfam PF00689 Cation transporting ATPase, C-terminus 700 876 6.0E-48 T 28-03-2018 IPR006068 Cation-transporting P-type ATPase, C-terminal Reactome: R-HSA-936837 ALX04_RS11810 08de8a2b2ca535a71ae0348371163e6f 286 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 156 175 1.4E-9 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR ALX04_RS11810 08de8a2b2ca535a71ae0348371163e6f 286 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 136 144 1.4E-9 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR ALX04_RS11810 08de8a2b2ca535a71ae0348371163e6f 286 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 82 93 1.4E-9 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR ALX04_RS11810 08de8a2b2ca535a71ae0348371163e6f 286 Gene3D G3DSA:3.40.50.720 1 281 1.5E-52 T 28-03-2018 ALX04_RS11810 08de8a2b2ca535a71ae0348371163e6f 286 SUPERFAMILY SSF51735 1 256 7.89E-60 T 28-03-2018 IPR016040 NAD(P)-binding domain ALX04_RS11810 08de8a2b2ca535a71ae0348371163e6f 286 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 1.4E-22 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR ALX04_RS11810 08de8a2b2ca535a71ae0348371163e6f 286 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 82 93 1.4E-22 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR ALX04_RS11810 08de8a2b2ca535a71ae0348371163e6f 286 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 179 196 1.4E-22 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR ALX04_RS11810 08de8a2b2ca535a71ae0348371163e6f 286 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 130 146 1.4E-22 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR ALX04_RS11810 08de8a2b2ca535a71ae0348371163e6f 286 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 156 175 1.4E-22 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR ALX04_RS11810 08de8a2b2ca535a71ae0348371163e6f 286 Pfam PF00106 short chain dehydrogenase 7 201 2.0E-50 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR ALX04_RS07960 00f17cbd2fded85973d4ddbc9bc8916d 211 SMART SM01057 3 210 1.3E-62 T 28-03-2018 IPR001148 Alpha carbonic anhydrase ALX04_RS07960 00f17cbd2fded85973d4ddbc9bc8916d 211 Gene3D G3DSA:3.10.200.10 1 210 6.7E-49 T 28-03-2018 IPR001148 Alpha carbonic anhydrase ALX04_RS07960 00f17cbd2fded85973d4ddbc9bc8916d 211 Pfam PF00194 Eukaryotic-type carbonic anhydrase 7 207 2.2E-35 T 28-03-2018 IPR001148 Alpha carbonic anhydrase ALX04_RS07960 00f17cbd2fded85973d4ddbc9bc8916d 211 SUPERFAMILY SSF51069 3 207 5.37E-56 T 28-03-2018 IPR001148 Alpha carbonic anhydrase ALX04_RS00495 21986819afa9ecd19e855ec2b9634598 39 Pfam PF00444 Ribosomal protein L36 1 38 2.9E-23 T 28-03-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 ALX04_RS00495 21986819afa9ecd19e855ec2b9634598 39 ProSitePatterns PS00828 Ribosomal protein L36 signature. 11 37 - T 28-03-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 ALX04_RS00495 21986819afa9ecd19e855ec2b9634598 39 Hamap MF_00251 50S ribosomal protein L36 [rpmJ]. 1 38 18.855 T 28-03-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 ALX04_RS00495 21986819afa9ecd19e855ec2b9634598 39 TIGRFAM TIGR01022 rpmJ_bact: ribosomal protein bL36 1 38 5.4E-23 T 28-03-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 ALX04_RS00495 21986819afa9ecd19e855ec2b9634598 39 SUPERFAMILY SSF57840 1 38 7.98E-18 T 28-03-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 ALX04_RS00495 21986819afa9ecd19e855ec2b9634598 39 ProDom PD002101 RIBOSOMAL L36 RIBONUCLEOPROTEIN 50S CHLOROPLAST PLASTID B SUBUNIT DIRECT SEQUENCING 10 38 6.0E-10 T 28-03-2018 ALX04_RS02700 ff87705b70e3429fcbaada953b8f405c 350 Pfam PF00557 Metallopeptidase family M24 132 334 7.0E-58 T 28-03-2018 IPR000994 Peptidase M24 ALX04_RS02700 ff87705b70e3429fcbaada953b8f405c 350 SUPERFAMILY SSF55920 124 349 1.44E-70 T 28-03-2018 IPR000994 Peptidase M24 ALX04_RS02700 ff87705b70e3429fcbaada953b8f405c 350 Gene3D G3DSA:3.90.230.10 123 350 6.8E-72 T 28-03-2018 ALX04_RS02700 ff87705b70e3429fcbaada953b8f405c 350 SUPERFAMILY SSF53092 7 123 2.62E-18 T 28-03-2018 IPR028980 Creatinase/Aminopeptidase P, N-terminal ALX04_RS02700 ff87705b70e3429fcbaada953b8f405c 350 Pfam PF01321 Creatinase/Prolidase N-terminal domain 3 123 4.9E-16 T 28-03-2018 IPR000587 Creatinase, N-terminal GO:0016787 ALX04_RS02700 ff87705b70e3429fcbaada953b8f405c 350 Gene3D G3DSA:3.40.350.10 1 122 7.7E-17 T 28-03-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal ALX04_RS02700 ff87705b70e3429fcbaada953b8f405c 350 ProSitePatterns PS00491 Aminopeptidase P and proline dipeptidase signature. 280 292 - T 28-03-2018 IPR001131 Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site ALX04_RS05460 31e28626ea57f626f2e1da26848d9366 332 Gene3D G3DSA:3.10.310.10 143 280 7.7E-29 T 28-03-2018 ALX04_RS05460 31e28626ea57f626f2e1da26848d9366 332 SUPERFAMILY SSF54506 4 136 1.05E-22 T 28-03-2018 ALX04_RS05460 31e28626ea57f626f2e1da26848d9366 332 ProSitePatterns PS01326 Diaminopimelate epimerase signature. 73 87 - T 28-03-2018 IPR018510 Diaminopimelate epimerase, active site GO:0005737|GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 ALX04_RS05460 31e28626ea57f626f2e1da26848d9366 332 Hamap MF_00197 Diaminopimelate epimerase [dapF]. 3 300 27.868 T 28-03-2018 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 ALX04_RS05460 31e28626ea57f626f2e1da26848d9366 332 Pfam PF01678 Diaminopimelate epimerase 169 285 6.2E-12 T 28-03-2018 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 ALX04_RS05460 31e28626ea57f626f2e1da26848d9366 332 Pfam PF01678 Diaminopimelate epimerase 6 120 7.5E-16 T 28-03-2018 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 ALX04_RS05460 31e28626ea57f626f2e1da26848d9366 332 TIGRFAM TIGR00652 DapF: diaminopimelate epimerase 5 292 2.9E-47 T 28-03-2018 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 ALX04_RS05460 31e28626ea57f626f2e1da26848d9366 332 Gene3D G3DSA:3.10.310.10 1 142 1.2E-27 T 28-03-2018 ALX04_RS05460 31e28626ea57f626f2e1da26848d9366 332 SUPERFAMILY SSF54506 156 293 2.17E-27 T 28-03-2018 ALX04_RS12460 b7f240dc9a564f0f8a647f772568b80a 116 Pfam PF08818 Domain of unknown function (DU1801) 16 105 2.1E-12 T 28-03-2018 IPR014922 Domain of unknown function DUF1801 ALX04_RS12460 b7f240dc9a564f0f8a647f772568b80a 116 SUPERFAMILY SSF159888 1 112 1.7E-33 T 28-03-2018 ALX04_RS03475 022648bda0c2474d8bf229af0a04ef78 225 Gene3D G3DSA:3.40.50.300 1 218 1.3E-33 T 28-03-2018 ALX04_RS03475 022648bda0c2474d8bf229af0a04ef78 225 Pfam PF00005 ABC transporter 20 153 1.1E-16 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 ALX04_RS03475 022648bda0c2474d8bf229af0a04ef78 225 ProSitePatterns PS00211 ABC transporters family signature. 125 139 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 ALX04_RS03475 022648bda0c2474d8bf229af0a04ef78 225 SUPERFAMILY SSF52540 5 203 3.25E-34 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase ALX04_RS03475 022648bda0c2474d8bf229af0a04ef78 225 SMART SM00382 28 199 7.0E-6 T 28-03-2018 IPR003593 AAA+ ATPase domain ALX04_RS07000 e5f8bc1ad77f9d0c0988843812d8e091 920 Pfam PF06458 MucBP domain 453 520 2.9E-11 T 28-03-2018 IPR009459 MucBP domain ALX04_RS07000 e5f8bc1ad77f9d0c0988843812d8e091 920 Pfam PF06458 MucBP domain 675 737 3.5E-10 T 28-03-2018 IPR009459 MucBP domain ALX04_RS07000 e5f8bc1ad77f9d0c0988843812d8e091 920 Pfam PF06458 MucBP domain 601 662 2.5E-11 T 28-03-2018 IPR009459 MucBP domain ALX04_RS07000 e5f8bc1ad77f9d0c0988843812d8e091 920 Pfam PF06458 MucBP domain 530 591 3.1E-11 T 28-03-2018 IPR009459 MucBP domain ALX04_RS07000 e5f8bc1ad77f9d0c0988843812d8e091 920 Pfam PF06458 MucBP domain 371 445 3.2E-14 T 28-03-2018 IPR009459 MucBP domain ALX04_RS07000 e5f8bc1ad77f9d0c0988843812d8e091 920 Gene3D G3DSA:3.10.20.320 600 670 1.6E-17 T 28-03-2018 ALX04_RS07000 e5f8bc1ad77f9d0c0988843812d8e091 920 Gene3D G3DSA:3.10.20.320 671 751 1.5E-13 T 28-03-2018 ALX04_RS07000 e5f8bc1ad77f9d0c0988843812d8e091 920 Gene3D G3DSA:3.10.20.320 364 448 3.1E-14 T 28-03-2018 ALX04_RS07000 e5f8bc1ad77f9d0c0988843812d8e091 920 Gene3D G3DSA:3.10.20.320 529 599 1.7E-17 T 28-03-2018 ALX04_RS07000 e5f8bc1ad77f9d0c0988843812d8e091 920 Gene3D G3DSA:3.10.20.320 449 528 7.9E-16 T 28-03-2018 ALX04_RS07000 e5f8bc1ad77f9d0c0988843812d8e091 920 TIGRFAM TIGR01167 LPXTG_anchor: LPXTG cell wall anchor domain 882 918 4.7E-6 T 28-03-2018 ALX04_RS07000 e5f8bc1ad77f9d0c0988843812d8e091 920 TIGRFAM TIGR03715 KxYKxGKxW: KxYKxGKxW signal peptide 14 35 2.8E-9 T 28-03-2018 IPR022263 KxYKxGKxW signal peptide ALX04_RS03935 5af3dfd0650d51ba3e4bc0f2cfc70fc0 479 SMART SM00487 15 203 8.2E-24 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain ALX04_RS03935 5af3dfd0650d51ba3e4bc0f2cfc70fc0 479 Pfam PF00271 Helicase conserved C-terminal domain 221 325 8.3E-19 T 28-03-2018 IPR001650 Helicase, C-terminal ALX04_RS03935 5af3dfd0650d51ba3e4bc0f2cfc70fc0 479 Pfam PF16124 RecQ zinc-binding 398 438 1.4E-5 T 28-03-2018 IPR032284 ATP-dependent DNA helicase RecQ, zinc-binding domain ALX04_RS03935 5af3dfd0650d51ba3e4bc0f2cfc70fc0 479 TIGRFAM TIGR00614 recQ_fam: ATP-dependent DNA helicase, RecQ family 9 361 1.5E-105 T 28-03-2018 IPR004589 DNA helicase, ATP-dependent, RecQ type GO:0006310|GO:0008026 ALX04_RS03935 5af3dfd0650d51ba3e4bc0f2cfc70fc0 479 SUPERFAMILY SSF52540 59 345 1.32E-58 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase ALX04_RS03935 5af3dfd0650d51ba3e4bc0f2cfc70fc0 479 SMART SM00490 244 326 2.7E-24 T 28-03-2018 IPR001650 Helicase, C-terminal ALX04_RS03935 5af3dfd0650d51ba3e4bc0f2cfc70fc0 479 ProSitePatterns PS00690 DEAH-box subfamily ATP-dependent helicases signature. 133 142 - T 28-03-2018 IPR002464 DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site ALX04_RS03935 5af3dfd0650d51ba3e4bc0f2cfc70fc0 479 Pfam PF00270 DEAD/DEAH box helicase 21 180 4.4E-19 T 28-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 ALX04_RS03935 5af3dfd0650d51ba3e4bc0f2cfc70fc0 479 Gene3D G3DSA:3.40.50.300 202 445 2.0E-45 T 28-03-2018 ALX04_RS03935 5af3dfd0650d51ba3e4bc0f2cfc70fc0 479 Gene3D G3DSA:3.40.50.300 2 200 2.1E-37 T 28-03-2018 ALX04_RS01365 cce04b40fa69f5569c1fd2150b2c4777 547 Gene3D G3DSA:3.10.105.10 300 518 1.9E-46 T 28-03-2018 ALX04_RS01365 cce04b40fa69f5569c1fd2150b2c4777 547 SUPERFAMILY SSF53850 30 543 6.66E-119 T 28-03-2018 ALX04_RS01365 cce04b40fa69f5569c1fd2150b2c4777 547 PIRSF PIRSF002741 1 547 3.1E-90 T 28-03-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 ALX04_RS01365 cce04b40fa69f5569c1fd2150b2c4777 547 Gene3D G3DSA:3.40.190.10 203 299 8.9E-20 T 28-03-2018 ALX04_RS01365 cce04b40fa69f5569c1fd2150b2c4777 547 Gene3D G3DSA:3.90.76.10 43 202 1.1E-38 T 28-03-2018 ALX04_RS01365 cce04b40fa69f5569c1fd2150b2c4777 547 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 76 467 3.5E-75 T 28-03-2018 IPR000914 Solute-binding protein family 5 domain ALX04_RS01365 cce04b40fa69f5569c1fd2150b2c4777 547 ProSitePatterns PS01040 Bacterial extracellular solute-binding proteins, family 5 signature. 82 104 - T 28-03-2018 IPR023765 Solute-binding protein family 5, conserved site ALX04_RS11620 4e188e70ab9c9f477c4ddac42c758e49 150 Pfam PF03948 Ribosomal protein L9, C-terminal domain 63 149 1.9E-29 T 28-03-2018 IPR020069 Ribosomal protein L9, C-terminal ALX04_RS11620 4e188e70ab9c9f477c4ddac42c758e49 150 Hamap MF_00503 50S ribosomal protein L9 [rplI]. 1 150 25.313 T 28-03-2018 IPR020594 Ribosomal protein L9, bacteria/chloroplast GO:0003735|GO:0005622|GO:0005840|GO:0006412 ALX04_RS11620 4e188e70ab9c9f477c4ddac42c758e49 150 Gene3D G3DSA:3.40.5.10 1 49 1.0E-20 T 28-03-2018 IPR020070 Ribosomal protein L9, N-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 ALX04_RS11620 4e188e70ab9c9f477c4ddac42c758e49 150 ProSitePatterns PS00651 Ribosomal protein L9 signature. 13 40 - T 28-03-2018 IPR020070 Ribosomal protein L9, N-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 ALX04_RS11620 4e188e70ab9c9f477c4ddac42c758e49 150 Pfam PF01281 Ribosomal protein L9, N-terminal domain 1 46 5.5E-20 T 28-03-2018 IPR020070 Ribosomal protein L9, N-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 ALX04_RS11620 4e188e70ab9c9f477c4ddac42c758e49 150 TIGRFAM TIGR00158 L9: ribosomal protein bL9 1 149 2.2E-45 T 28-03-2018 IPR020594 Ribosomal protein L9, bacteria/chloroplast GO:0003735|GO:0005622|GO:0005840|GO:0006412 ALX04_RS11620 4e188e70ab9c9f477c4ddac42c758e49 150 Gene3D G3DSA:3.10.430.100 63 149 5.0E-29 T 28-03-2018 IPR020069 Ribosomal protein L9, C-terminal ALX04_RS11620 4e188e70ab9c9f477c4ddac42c758e49 150 SUPERFAMILY SSF55658 1 56 1.05E-15 T 28-03-2018 IPR009027 Ribosomal protein L9/RNase H1, N-terminal ALX04_RS11620 4e188e70ab9c9f477c4ddac42c758e49 150 SUPERFAMILY SSF55653 57 149 2.49E-27 T 28-03-2018 IPR020069 Ribosomal protein L9, C-terminal ALX04_RS02080 e0c2af6ffc0b18d9a1a1f831d68916f5 331 SUPERFAMILY SSF53448 1 228 4.1E-30 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases ALX04_RS02080 e0c2af6ffc0b18d9a1a1f831d68916f5 331 Pfam PF00535 Glycosyl transferase family 2 7 176 3.8E-25 T 28-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 ALX04_RS02080 e0c2af6ffc0b18d9a1a1f831d68916f5 331 Gene3D G3DSA:3.90.550.10 1 216 8.5E-30 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases ALX04_RS08765 bb32f92721436c02390215caa15ca2f6 215 SUPERFAMILY SSF46689 38 98 6.62E-12 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 ALX04_RS08765 bb32f92721436c02390215caa15ca2f6 215 Gene3D G3DSA:1.10.10.60 77 165 5.4E-5 T 28-03-2018 ALX04_RS08765 bb32f92721436c02390215caa15ca2f6 215 Gene3D G3DSA:1.10.10.60 36 76 2.6E-10 T 28-03-2018 ALX04_RS08765 bb32f92721436c02390215caa15ca2f6 215 Pfam PF00440 Bacterial regulatory proteins, tetR family 48 87 2.2E-5 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 ALX04_RS05185 f46615d5c4292b24951a4da8cc20e953 135 SUPERFAMILY SSF89360 1 112 1.33E-27 T 28-03-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 ALX04_RS05185 f46615d5c4292b24951a4da8cc20e953 135 Gene3D G3DSA:2.60.300.12 1 113 4.5E-31 T 28-03-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 ALX04_RS05185 f46615d5c4292b24951a4da8cc20e953 135 Pfam PF01521 Iron-sulphur cluster biosynthesis 1 110 2.3E-25 T 28-03-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 ALX04_RS06455 9424367fc347a08f49abe9a35fe542d9 209 Gene3D G3DSA:3.40.50.2020 3 207 2.5E-66 T 28-03-2018 ALX04_RS06455 9424367fc347a08f49abe9a35fe542d9 209 TIGRFAM TIGR01091 upp: uracil phosphoribosyltransferase 4 209 7.2E-91 T 28-03-2018 IPR005765 Uracil phosphoribosyl transferase GO:0004845|GO:0006223 KEGG: 00240+2.4.2.9|MetaCyc: PWY-7183 ALX04_RS06455 9424367fc347a08f49abe9a35fe542d9 209 Pfam PF14681 Uracil phosphoribosyltransferase 6 208 8.1E-76 T 28-03-2018 ALX04_RS06455 9424367fc347a08f49abe9a35fe542d9 209 Hamap MF_01218_B Uracil phosphoribosyltransferase [upp]. 3 209 48.059 T 28-03-2018 IPR034332 Uracil phosphoribosyltransferase, bacterial-type KEGG: 00240+2.4.2.9|MetaCyc: PWY-7183 ALX04_RS06455 9424367fc347a08f49abe9a35fe542d9 209 SUPERFAMILY SSF53271 6 207 7.21E-73 T 28-03-2018 IPR029057 Phosphoribosyltransferase-like ALX04_RS00960 2df48651958a3370754f418fb242bfdc 435 PIRSF PIRSF006351 1 435 4.7E-111 T 28-03-2018 IPR004796 Phosphotransferase system, cellobiose-type IIC component GO:0008982|GO:0009401|GO:0016021 ALX04_RS00960 2df48651958a3370754f418fb242bfdc 435 Pfam PF02378 Phosphotransferase system, EIIC 27 359 5.7E-26 T 28-03-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 ALX04_RS08745 9ba6b15e36c99974c36499dd5d84edde 464 Pfam PF07690 Major Facilitator Superfamily 20 410 2.9E-38 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 ALX04_RS08745 9ba6b15e36c99974c36499dd5d84edde 464 SUPERFAMILY SSF103473 8 192 1.09E-47 T 28-03-2018 IPR020846 Major facilitator superfamily domain ALX04_RS08745 9ba6b15e36c99974c36499dd5d84edde 464 SUPERFAMILY SSF103473 249 459 1.09E-47 T 28-03-2018 IPR020846 Major facilitator superfamily domain ALX04_RS08745 9ba6b15e36c99974c36499dd5d84edde 464 Gene3D G3DSA:1.20.1250.20 2 192 6.9E-23 T 28-03-2018 ALX04_RS08745 9ba6b15e36c99974c36499dd5d84edde 464 Gene3D G3DSA:1.20.1250.20 253 462 2.8E-17 T 28-03-2018 ALX04_RS08745 9ba6b15e36c99974c36499dd5d84edde 464 PRINTS PR01036 Tetracycline resistance protein TetB signature 138 162 5.2E-8 T 28-03-2018 ALX04_RS08745 9ba6b15e36c99974c36499dd5d84edde 464 PRINTS PR01036 Tetracycline resistance protein TetB signature 77 99 5.2E-8 T 28-03-2018 ALX04_RS08745 9ba6b15e36c99974c36499dd5d84edde 464 PRINTS PR01036 Tetracycline resistance protein TetB signature 17 41 5.2E-8 T 28-03-2018 ALX04_RS08745 9ba6b15e36c99974c36499dd5d84edde 464 PRINTS PR01036 Tetracycline resistance protein TetB signature 303 327 5.2E-8 T 28-03-2018 ALX04_RS01735 edc122bab2fa2538ae8b03c5bd6b5c68 328 SUPERFAMILY SSF52540 4 189 1.5E-19 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase ALX04_RS01735 edc122bab2fa2538ae8b03c5bd6b5c68 328 PIRSF PIRSF036612 1 328 6.7E-142 T 28-03-2018 IPR012046 LytTR transcriptional regulator with ABC transporter ATP-binding domain ALX04_RS01735 edc122bab2fa2538ae8b03c5bd6b5c68 328 Gene3D G3DSA:2.20.25.10 291 327 5.0E-6 T 28-03-2018 ALX04_RS01735 edc122bab2fa2538ae8b03c5bd6b5c68 328 SMART SM00850 230 327 5.6E-30 T 28-03-2018 IPR007492 LytTR DNA-binding domain GO:0003677 ALX04_RS01735 edc122bab2fa2538ae8b03c5bd6b5c68 328 Gene3D G3DSA:3.40.50.300 1 198 1.4E-20 T 28-03-2018 ALX04_RS01735 edc122bab2fa2538ae8b03c5bd6b5c68 328 Gene3D G3DSA:2.40.50.40 223 290 6.1E-15 T 28-03-2018 ALX04_RS01735 edc122bab2fa2538ae8b03c5bd6b5c68 328 Pfam PF04397 LytTr DNA-binding domain 231 326 5.2E-24 T 28-03-2018 IPR007492 LytTR DNA-binding domain GO:0003677 ALX04_RS01735 edc122bab2fa2538ae8b03c5bd6b5c68 328 Pfam PF00005 ABC transporter 42 145 3.7E-7 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 ALX04_RS14780 48b3b5df52d3fa9294e2be8f521e7186 517 Gene3D G3DSA:1.10.3080.10 1 429 6.4E-86 T 28-03-2018 IPR014743 Chloride channel, core GO:0005216|GO:0055085 Reactome: R-HSA-2672351 ALX04_RS14780 48b3b5df52d3fa9294e2be8f521e7186 517 Pfam PF02080 TrkA-C domain 444 501 2.1E-10 T 28-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 ALX04_RS14780 48b3b5df52d3fa9294e2be8f521e7186 517 SUPERFAMILY SSF81340 9 435 3.92E-106 T 28-03-2018 IPR014743 Chloride channel, core GO:0005216|GO:0055085 Reactome: R-HSA-2672351 ALX04_RS14780 48b3b5df52d3fa9294e2be8f521e7186 517 PRINTS PR00762 Chloride channel signature 165 184 2.8E-23 T 28-03-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 ALX04_RS14780 48b3b5df52d3fa9294e2be8f521e7186 517 PRINTS PR00762 Chloride channel signature 420 434 2.8E-23 T 28-03-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 ALX04_RS14780 48b3b5df52d3fa9294e2be8f521e7186 517 PRINTS PR00762 Chloride channel signature 85 102 2.8E-23 T 28-03-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 ALX04_RS14780 48b3b5df52d3fa9294e2be8f521e7186 517 PRINTS PR00762 Chloride channel signature 381 400 2.8E-23 T 28-03-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 ALX04_RS14780 48b3b5df52d3fa9294e2be8f521e7186 517 PRINTS PR00762 Chloride channel signature 328 348 2.8E-23 T 28-03-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 ALX04_RS14780 48b3b5df52d3fa9294e2be8f521e7186 517 Pfam PF00654 Voltage gated chloride channel 73 413 1.3E-86 T 28-03-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 ALX04_RS14780 48b3b5df52d3fa9294e2be8f521e7186 517 Gene3D G3DSA:3.30.70.1450 437 514 4.5E-12 T 28-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 ALX04_RS14780 48b3b5df52d3fa9294e2be8f521e7186 517 SUPERFAMILY SSF116726 443 509 2.35E-11 T 28-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 ALX04_RS12435 077b16eb4c883144274d0eec2ed80338 392 Gene3D G3DSA:3.30.70.260 304 386 8.6E-13 T 28-03-2018 ALX04_RS12435 077b16eb4c883144274d0eec2ed80338 392 SUPERFAMILY SSF51735 81 271 1.51E-40 T 28-03-2018 IPR016040 NAD(P)-binding domain ALX04_RS12435 077b16eb4c883144274d0eec2ed80338 392 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 19 298 2.5E-14 T 28-03-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0008152|GO:0016616|GO:0051287|GO:0055114 ALX04_RS12435 077b16eb4c883144274d0eec2ed80338 392 SUPERFAMILY SSF55021 312 386 7.08E-13 T 28-03-2018 ALX04_RS12435 077b16eb4c883144274d0eec2ed80338 392 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 91 270 1.0E-36 T 28-03-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 ALX04_RS12435 077b16eb4c883144274d0eec2ed80338 392 SUPERFAMILY SSF52283 17 103 1.13E-17 T 28-03-2018 ALX04_RS12435 077b16eb4c883144274d0eec2ed80338 392 Gene3D G3DSA:3.40.50.720 9 93 4.8E-17 T 28-03-2018 ALX04_RS12435 077b16eb4c883144274d0eec2ed80338 392 ProSitePatterns PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. 136 163 - T 28-03-2018 IPR029752 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 ALX04_RS12435 077b16eb4c883144274d0eec2ed80338 392 ProSitePatterns PS00670 D-isomer specific 2-hydroxyacid dehydrogenases signature 2. 187 209 - T 28-03-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site ALX04_RS12435 077b16eb4c883144274d0eec2ed80338 392 Gene3D G3DSA:3.40.50.720 94 273 1.9E-40 T 28-03-2018 ALX04_RS03340 a126dde9afbe8f9ce298abb737fcc532 432 Hamap MF_00534 Asparagine--tRNA ligase [asnS]. 3 432 40.998 T 28-03-2018 IPR004522 Asparagine-tRNA ligase GO:0000166|GO:0004816|GO:0005524|GO:0005737|GO:0006421 KEGG: 00970+6.1.1.22 ALX04_RS03340 a126dde9afbe8f9ce298abb737fcc532 432 TIGRFAM TIGR00457 asnS: asparagine--tRNA ligase 9 431 4.5E-153 T 28-03-2018 IPR004522 Asparagine-tRNA ligase GO:0000166|GO:0004816|GO:0005524|GO:0005737|GO:0006421 KEGG: 00970+6.1.1.22 ALX04_RS03340 a126dde9afbe8f9ce298abb737fcc532 432 Gene3D G3DSA:2.40.50.140 13 102 5.6E-18 T 28-03-2018 ALX04_RS03340 a126dde9afbe8f9ce298abb737fcc532 432 Pfam PF01336 OB-fold nucleic acid binding domain 18 96 2.4E-11 T 28-03-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 ALX04_RS03340 a126dde9afbe8f9ce298abb737fcc532 432 PRINTS PR01042 Aspartyl-tRNA synthetase signature 347 363 6.7E-15 T 28-03-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 ALX04_RS03340 a126dde9afbe8f9ce298abb737fcc532 432 PRINTS PR01042 Aspartyl-tRNA synthetase signature 182 194 6.7E-15 T 28-03-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 ALX04_RS03340 a126dde9afbe8f9ce298abb737fcc532 432 PRINTS PR01042 Aspartyl-tRNA synthetase signature 387 401 6.7E-15 T 28-03-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 ALX04_RS03340 a126dde9afbe8f9ce298abb737fcc532 432 PRINTS PR01042 Aspartyl-tRNA synthetase signature 198 211 6.7E-15 T 28-03-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 ALX04_RS03340 a126dde9afbe8f9ce298abb737fcc532 432 Gene3D G3DSA:3.30.930.10 103 432 3.0E-88 T 28-03-2018 ALX04_RS03340 a126dde9afbe8f9ce298abb737fcc532 432 SUPERFAMILY SSF55681 99 431 8.3E-94 T 28-03-2018 ALX04_RS03340 a126dde9afbe8f9ce298abb737fcc532 432 SUPERFAMILY SSF50249 11 104 2.42E-21 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold ALX04_RS03340 a126dde9afbe8f9ce298abb737fcc532 432 Pfam PF00152 tRNA synthetases class II (D, K and N) 113 426 1.0E-75 T 28-03-2018 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 ALX04_RS00080 037dac278026da4cc4da596ba7fbc216 602 Gene3D G3DSA:3.40.50.300 5 203 3.9E-34 T 28-03-2018 ALX04_RS00080 037dac278026da4cc4da596ba7fbc216 602 SMART SM00490 245 326 8.3E-23 T 28-03-2018 IPR001650 Helicase, C-terminal ALX04_RS00080 037dac278026da4cc4da596ba7fbc216 602 SUPERFAMILY SSF46785 397 540 4.76E-31 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS00080 037dac278026da4cc4da596ba7fbc216 602 Pfam PF00271 Helicase conserved C-terminal domain 219 325 1.1E-16 T 28-03-2018 IPR001650 Helicase, C-terminal ALX04_RS00080 037dac278026da4cc4da596ba7fbc216 602 Gene3D G3DSA:3.40.50.300 206 347 4.1E-28 T 28-03-2018 ALX04_RS00080 037dac278026da4cc4da596ba7fbc216 602 Pfam PF00270 DEAD/DEAH box helicase 22 183 1.9E-19 T 28-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 ALX04_RS00080 037dac278026da4cc4da596ba7fbc216 602 Pfam PF09382 RQC domain 402 510 5.8E-28 T 28-03-2018 IPR018982 RQC domain GO:0006260|GO:0006281|GO:0043140 Reactome: R-HSA-3108214|Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473 ALX04_RS00080 037dac278026da4cc4da596ba7fbc216 602 TIGRFAM TIGR01389 recQ: ATP-dependent DNA helicase RecQ 7 587 1.4E-238 T 28-03-2018 IPR006293 DNA helicase, ATP-dependent, RecQ type, bacterial GO:0004003|GO:0006310|GO:0009432 ALX04_RS00080 037dac278026da4cc4da596ba7fbc216 602 TIGRFAM TIGR00614 recQ_fam: ATP-dependent DNA helicase, RecQ family 9 455 3.9E-140 T 28-03-2018 IPR004589 DNA helicase, ATP-dependent, RecQ type GO:0006310|GO:0008026 ALX04_RS00080 037dac278026da4cc4da596ba7fbc216 602 SMART SM00341 515 595 2.6E-19 T 28-03-2018 IPR002121 HRDC domain GO:0003676|GO:0005622 ALX04_RS00080 037dac278026da4cc4da596ba7fbc216 602 SMART SM00956 406 509 6.5E-38 T 28-03-2018 IPR018982 RQC domain GO:0006260|GO:0006281|GO:0043140 Reactome: R-HSA-3108214|Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473 ALX04_RS00080 037dac278026da4cc4da596ba7fbc216 602 SUPERFAMILY SSF52540 60 347 6.19E-55 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase ALX04_RS00080 037dac278026da4cc4da596ba7fbc216 602 Gene3D G3DSA:1.10.10.10 348 508 2.6E-44 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS00080 037dac278026da4cc4da596ba7fbc216 602 Pfam PF00570 HRDC domain 520 585 6.0E-21 T 28-03-2018 IPR002121 HRDC domain GO:0003676|GO:0005622 ALX04_RS00080 037dac278026da4cc4da596ba7fbc216 602 SMART SM00487 16 213 3.3E-31 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain ALX04_RS00080 037dac278026da4cc4da596ba7fbc216 602 Pfam PF16124 RecQ zinc-binding 339 398 1.5E-15 T 28-03-2018 IPR032284 ATP-dependent DNA helicase RecQ, zinc-binding domain ALX04_RS00080 037dac278026da4cc4da596ba7fbc216 602 Gene3D G3DSA:1.10.150.80 509 598 7.2E-26 T 28-03-2018 ALX04_RS00080 037dac278026da4cc4da596ba7fbc216 602 SUPERFAMILY SSF47819 516 588 5.42E-24 T 28-03-2018 IPR010997 HRDC-like GO:0000166|GO:0003824|GO:0044237 ALX04_RS13135 8d0512a632e09d4461e925f07c79629c 169 Gene3D G3DSA:3.90.280.10 4 166 1.7E-40 T 28-03-2018 IPR008914 Phosphatidylethanolamine-binding protein ALX04_RS13135 8d0512a632e09d4461e925f07c79629c 169 Pfam PF01161 Phosphatidylethanolamine-binding protein 28 165 6.4E-33 T 28-03-2018 IPR008914 Phosphatidylethanolamine-binding protein ALX04_RS13135 8d0512a632e09d4461e925f07c79629c 169 SUPERFAMILY SSF49777 9 164 1.96E-35 T 28-03-2018 IPR008914 Phosphatidylethanolamine-binding protein ALX04_RS13135 8d0512a632e09d4461e925f07c79629c 169 TIGRFAM TIGR00481 TIGR00481: Raf kinase inhibitor-like protein, YbhB/YbcL family 27 165 1.1E-39 T 28-03-2018 IPR005247 YbhB/YbcL ALX04_RS05310 e225766c34ca9e3e2c8df99c1dc356e7 612 Gene3D G3DSA:2.40.50.250 495 577 5.0E-35 T 28-03-2018 ALX04_RS05310 e225766c34ca9e3e2c8df99c1dc356e7 612 Gene3D G3DSA:2.40.30.10 199 306 6.5E-23 T 28-03-2018 ALX04_RS05310 e225766c34ca9e3e2c8df99c1dc356e7 612 Gene3D G3DSA:3.40.50.300 2 69 3.5E-10 T 28-03-2018 ALX04_RS05310 e225766c34ca9e3e2c8df99c1dc356e7 612 Gene3D G3DSA:3.40.50.300 70 198 6.3E-33 T 28-03-2018 ALX04_RS05310 e225766c34ca9e3e2c8df99c1dc356e7 612 Gene3D G3DSA:3.30.70.240 405 494 1.4E-20 T 28-03-2018 ALX04_RS05310 e225766c34ca9e3e2c8df99c1dc356e7 612 SUPERFAMILY SSF54980 402 517 3.17E-28 T 28-03-2018 IPR035647 EF-G domain III/V-like ALX04_RS05310 e225766c34ca9e3e2c8df99c1dc356e7 612 SUPERFAMILY SSF54980 306 391 2.95E-14 T 28-03-2018 IPR035647 EF-G domain III/V-like ALX04_RS05310 e225766c34ca9e3e2c8df99c1dc356e7 612 Pfam PF14492 Elongation Factor G, domain II 333 380 4.5E-7 T 28-03-2018 ALX04_RS05310 e225766c34ca9e3e2c8df99c1dc356e7 612 TIGRFAM TIGR01394 TypA_BipA: GTP-binding protein TypA/BipA 7 603 3.0E-277 T 28-03-2018 IPR006298 GTP-binding protein TypA GO:0005525 ALX04_RS05310 e225766c34ca9e3e2c8df99c1dc356e7 612 SUPERFAMILY SSF52540 3 210 4.42E-57 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase ALX04_RS05310 e225766c34ca9e3e2c8df99c1dc356e7 612 Gene3D G3DSA:3.30.70.870 307 404 1.4E-33 T 28-03-2018 ALX04_RS05310 e225766c34ca9e3e2c8df99c1dc356e7 612 PRINTS PR00315 GTP-binding elongation factor signature 9 22 2.5E-14 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 ALX04_RS05310 e225766c34ca9e3e2c8df99c1dc356e7 612 PRINTS PR00315 GTP-binding elongation factor signature 53 61 2.5E-14 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 ALX04_RS05310 e225766c34ca9e3e2c8df99c1dc356e7 612 PRINTS PR00315 GTP-binding elongation factor signature 73 83 2.5E-14 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 ALX04_RS05310 e225766c34ca9e3e2c8df99c1dc356e7 612 PRINTS PR00315 GTP-binding elongation factor signature 89 100 2.5E-14 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 ALX04_RS05310 e225766c34ca9e3e2c8df99c1dc356e7 612 PRINTS PR00315 GTP-binding elongation factor signature 125 134 2.5E-14 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 ALX04_RS05310 e225766c34ca9e3e2c8df99c1dc356e7 612 SMART SM00838 402 487 4.7E-4 T 28-03-2018 IPR000640 Elongation factor EFG, domain V-like ALX04_RS05310 e225766c34ca9e3e2c8df99c1dc356e7 612 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 7 146 9.8E-22 T 28-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 ALX04_RS05310 e225766c34ca9e3e2c8df99c1dc356e7 612 Pfam PF00679 Elongation factor G C-terminus 401 479 6.1E-24 T 28-03-2018 IPR000640 Elongation factor EFG, domain V-like ALX04_RS05310 e225766c34ca9e3e2c8df99c1dc356e7 612 Pfam PF03144 Elongation factor Tu domain 2 223 292 1.6E-14 T 28-03-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 ALX04_RS05310 e225766c34ca9e3e2c8df99c1dc356e7 612 SUPERFAMILY SSF50447 154 303 2.65E-32 T 28-03-2018 IPR009000 Translation protein, beta-barrel domain ALX04_RS05310 e225766c34ca9e3e2c8df99c1dc356e7 612 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 46 61 - T 28-03-2018 IPR031157 Tr-type G domain, conserved site ALX04_RS05310 e225766c34ca9e3e2c8df99c1dc356e7 612 Pfam PF00009 Elongation factor Tu GTP binding domain 6 200 4.7E-54 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 ALX04_RS15270 52dd14dea67ec981ec8aaa203a5f5f21 768 Gene3D G3DSA:3.40.50.300 208 590 2.4E-25 T 28-03-2018 ALX04_RS15270 52dd14dea67ec981ec8aaa203a5f5f21 768 SUPERFAMILY SSF52540 490 749 9.3E-50 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase ALX04_RS15270 52dd14dea67ec981ec8aaa203a5f5f21 768 SUPERFAMILY SSF52540 202 321 9.3E-50 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase ALX04_RS15270 52dd14dea67ec981ec8aaa203a5f5f21 768 Pfam PF13538 UvrD-like helicase C-terminal domain 702 744 8.8E-10 T 28-03-2018 IPR027785 UvrD-like helicase C-terminal domain ALX04_RS15270 52dd14dea67ec981ec8aaa203a5f5f21 768 Pfam PF13245 AAA domain 214 568 1.3E-7 T 28-03-2018 ALX04_RS15270 52dd14dea67ec981ec8aaa203a5f5f21 768 Gene3D G3DSA:3.40.50.300 594 767 4.8E-29 T 28-03-2018 ALX04_RS06500 87aa6272895f57ffa21d5fc91380b576 339 Gene3D G3DSA:3.40.710.10 4 338 6.5E-63 T 28-03-2018 ALX04_RS06500 87aa6272895f57ffa21d5fc91380b576 339 Pfam PF00144 Beta-lactamase 8 315 2.8E-54 T 28-03-2018 IPR001466 Beta-lactamase-related ALX04_RS06500 87aa6272895f57ffa21d5fc91380b576 339 SUPERFAMILY SSF56601 4 328 7.89E-68 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like ALX04_RS00415 81c0b12f386e40cf61259d89f56c34b6 144 Pfam PF00252 Ribosomal protein L16p/L10e 4 132 6.5E-49 T 28-03-2018 IPR016180 Ribosomal protein L10e/L16 GO:0003735|GO:0005840|GO:0006412 ALX04_RS00415 81c0b12f386e40cf61259d89f56c34b6 144 PRINTS PR00060 Ribosomal protein L16 signature 58 87 1.1E-33 T 28-03-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 ALX04_RS00415 81c0b12f386e40cf61259d89f56c34b6 144 PRINTS PR00060 Ribosomal protein L16 signature 88 117 1.1E-33 T 28-03-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 ALX04_RS00415 81c0b12f386e40cf61259d89f56c34b6 144 PRINTS PR00060 Ribosomal protein L16 signature 24 36 1.1E-33 T 28-03-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 ALX04_RS00415 81c0b12f386e40cf61259d89f56c34b6 144 PRINTS PR00060 Ribosomal protein L16 signature 42 53 1.1E-33 T 28-03-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 ALX04_RS00415 81c0b12f386e40cf61259d89f56c34b6 144 TIGRFAM TIGR01164 rplP_bact: ribosomal protein uL16 2 127 2.5E-56 T 28-03-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 ALX04_RS00415 81c0b12f386e40cf61259d89f56c34b6 144 Hamap MF_01342 50S ribosomal protein L16 [rplP]. 1 134 37.493 T 28-03-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 ALX04_RS00415 81c0b12f386e40cf61259d89f56c34b6 144 ProSitePatterns PS00701 Ribosomal protein L16 signature 2. 82 93 - T 28-03-2018 IPR020798 Ribosomal protein L16, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 ALX04_RS00415 81c0b12f386e40cf61259d89f56c34b6 144 Gene3D G3DSA:3.90.1170.10 2 139 5.0E-50 T 28-03-2018 IPR016180 Ribosomal protein L10e/L16 GO:0003735|GO:0005840|GO:0006412 ALX04_RS00415 81c0b12f386e40cf61259d89f56c34b6 144 SUPERFAMILY SSF54686 1 137 1.05E-55 T 28-03-2018 IPR016180 Ribosomal protein L10e/L16 GO:0003735|GO:0005840|GO:0006412 ALX04_RS00415 81c0b12f386e40cf61259d89f56c34b6 144 ProSitePatterns PS00586 Ribosomal protein L16 signature 1. 59 70 - T 28-03-2018 IPR020798 Ribosomal protein L16, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 ALX04_RS06050 4c2ab3bffcf7fb3adf800e7167b2b2fa 336 Hamap MF_00016 Holliday junction ATP-dependent DNA helicase RuvB [ruvB]. 1 336 162.354 T 28-03-2018 IPR004605 DNA helicase, Holliday junction RuvB type GO:0003677|GO:0005524|GO:0006281|GO:0006310|GO:0009378 ALX04_RS06050 4c2ab3bffcf7fb3adf800e7167b2b2fa 336 TIGRFAM TIGR00635 ruvB: Holliday junction DNA helicase RuvB 26 329 3.6E-139 T 28-03-2018 IPR004605 DNA helicase, Holliday junction RuvB type GO:0003677|GO:0005524|GO:0006281|GO:0006310|GO:0009378 ALX04_RS06050 4c2ab3bffcf7fb3adf800e7167b2b2fa 336 Gene3D G3DSA:3.40.50.300 7 182 2.7E-27 T 28-03-2018 ALX04_RS06050 4c2ab3bffcf7fb3adf800e7167b2b2fa 336 SMART SM00382 54 185 2.4E-12 T 28-03-2018 IPR003593 AAA+ ATPase domain ALX04_RS06050 4c2ab3bffcf7fb3adf800e7167b2b2fa 336 Pfam PF05491 Holliday junction DNA helicase ruvB C-terminus 256 329 5.1E-32 T 28-03-2018 IPR008823 DNA helicase, Holliday junction RuvB type, C-terminal GO:0003677|GO:0006281|GO:0006310|GO:0009378 ALX04_RS06050 4c2ab3bffcf7fb3adf800e7167b2b2fa 336 Pfam PF05496 Holliday junction DNA helicase ruvB N-terminus 11 238 4.6E-114 T 28-03-2018 IPR008824 Holliday junction DNA helicase ruvB, N-terminal GO:0006281|GO:0006310|GO:0009378 ALX04_RS06050 4c2ab3bffcf7fb3adf800e7167b2b2fa 336 SUPERFAMILY SSF52540 23 255 2.91E-52 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase ALX04_RS06050 4c2ab3bffcf7fb3adf800e7167b2b2fa 336 SUPERFAMILY SSF46785 260 333 1.22E-24 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS06050 4c2ab3bffcf7fb3adf800e7167b2b2fa 336 ProDom PD005323 DNA HELICASE HOLLIDAY JUNCTION RUVB NUCLEOTIDE-BINDING ATP-BINDING SOS RECOMBINATION RESPONSE 254 332 2.0E-39 T 28-03-2018 IPR008823 DNA helicase, Holliday junction RuvB type, C-terminal GO:0003677|GO:0006281|GO:0006310|GO:0009378 ALX04_RS06050 4c2ab3bffcf7fb3adf800e7167b2b2fa 336 Gene3D G3DSA:1.10.8.60 187 257 6.6E-28 T 28-03-2018 ALX04_RS06050 4c2ab3bffcf7fb3adf800e7167b2b2fa 336 Gene3D G3DSA:1.10.10.10 260 330 1.8E-31 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS03745 6efd978330b84e472e19d7639bae8a6a 319 SUPERFAMILY SSF53850 94 303 6.98E-21 T 28-03-2018 ALX04_RS03745 6efd978330b84e472e19d7639bae8a6a 319 Gene3D G3DSA:3.40.190.10 189 275 4.2E-5 T 28-03-2018 ALX04_RS03745 6efd978330b84e472e19d7639bae8a6a 319 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 13 69 2.3E-16 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 ALX04_RS03745 6efd978330b84e472e19d7639bae8a6a 319 Pfam PF03466 LysR substrate binding domain 97 301 2.8E-23 T 28-03-2018 IPR005119 LysR, substrate-binding ALX04_RS03745 6efd978330b84e472e19d7639bae8a6a 319 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 37 47 2.2E-7 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 ALX04_RS03745 6efd978330b84e472e19d7639bae8a6a 319 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 26 37 2.2E-7 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 ALX04_RS03745 6efd978330b84e472e19d7639bae8a6a 319 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 47 58 2.2E-7 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 ALX04_RS03745 6efd978330b84e472e19d7639bae8a6a 319 Gene3D G3DSA:1.10.10.10 1 94 6.3E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS03745 6efd978330b84e472e19d7639bae8a6a 319 SUPERFAMILY SSF46785 9 91 1.25E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS03745 6efd978330b84e472e19d7639bae8a6a 319 Gene3D G3DSA:3.40.190.10 99 188 1.5E-10 T 28-03-2018 ALX04_RS03770 52d817bf9b0492638ad813e9b2e3c984 472 SUPERFAMILY SSF52540 7 141 7.96E-81 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase ALX04_RS03770 52d817bf9b0492638ad813e9b2e3c984 472 SUPERFAMILY SSF52540 210 470 7.96E-81 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase ALX04_RS03770 52d817bf9b0492638ad813e9b2e3c984 472 Gene3D G3DSA:3.40.50.300 1 376 1.1E-50 T 28-03-2018 ALX04_RS03770 52d817bf9b0492638ad813e9b2e3c984 472 Hamap MF_00249 ATP-dependent protease ATPase subunit HslU [hslU]. 3 472 40.389 T 28-03-2018 IPR004491 Heat shock protein HslU GO:0005524|GO:0005737|GO:0009376|GO:0016887|GO:0070011 ALX04_RS03770 52d817bf9b0492638ad813e9b2e3c984 472 SMART SM00382 51 365 2.8E-11 T 28-03-2018 IPR003593 AAA+ ATPase domain ALX04_RS03770 52d817bf9b0492638ad813e9b2e3c984 472 Gene3D G3DSA:1.10.8.60 377 460 7.5E-31 T 28-03-2018 ALX04_RS03770 52d817bf9b0492638ad813e9b2e3c984 472 Pfam PF07724 AAA domain (Cdc48 subfamily) 231 358 3.8E-37 T 28-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 ALX04_RS03770 52d817bf9b0492638ad813e9b2e3c984 472 TIGRFAM TIGR00390 hslU: ATP-dependent protease HslVU, ATPase subunit 7 472 1.4E-180 T 28-03-2018 IPR004491 Heat shock protein HslU GO:0005524|GO:0005737|GO:0009376|GO:0016887|GO:0070011 ALX04_RS03770 52d817bf9b0492638ad813e9b2e3c984 472 SMART SM01086 364 458 7.5E-25 T 28-03-2018 IPR019489 Clp ATPase, C-terminal ALX04_RS03770 52d817bf9b0492638ad813e9b2e3c984 472 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 364 438 1.4E-6 T 28-03-2018 IPR019489 Clp ATPase, C-terminal ALX04_RS03770 52d817bf9b0492638ad813e9b2e3c984 472 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 55 109 2.1E-6 T 28-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 ALX04_RS14420 3676e242dedd3575765082e14584fb76 366 TIGRFAM TIGR03301 PhnW-AepZ: 2-aminoethylphosphonate aminotransferase 6 361 3.1E-169 T 28-03-2018 IPR012703 2-aminoethylphosphonate--pyruvate transaminase GO:0019700|GO:0047304 KEGG: 00440+2.6.1.37|MetaCyc: PWY-6832 ALX04_RS14420 3676e242dedd3575765082e14584fb76 366 Pfam PF00266 Aminotransferase class-V 34 337 2.9E-23 T 28-03-2018 IPR000192 Aminotransferase class V domain ALX04_RS14420 3676e242dedd3575765082e14584fb76 366 Gene3D G3DSA:3.40.640.10 16 254 2.8E-26 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 ALX04_RS14420 3676e242dedd3575765082e14584fb76 366 PIRSF PIRSF000524 1 365 7.7E-55 T 28-03-2018 IPR024169 Serine-pyruvate aminotransferase/2-aminoethylphosphonate-pyruvate transaminase KEGG: 00440+2.6.1.37|MetaCyc: PWY-6832|Reactome: R-HSA-389661 ALX04_RS14420 3676e242dedd3575765082e14584fb76 366 SUPERFAMILY SSF53383 3 363 1.41E-78 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase ALX04_RS14420 3676e242dedd3575765082e14584fb76 366 Gene3D G3DSA:3.90.1150.10 255 360 3.2E-25 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 ALX04_RS14420 3676e242dedd3575765082e14584fb76 366 TIGRFAM TIGR02326 transamin_PhnW: 2-aminoethylphosphonate--pyruvate transaminase 2 364 4.4E-191 T 28-03-2018 IPR012703 2-aminoethylphosphonate--pyruvate transaminase GO:0019700|GO:0047304 KEGG: 00440+2.6.1.37|MetaCyc: PWY-6832 ALX04_RS14420 3676e242dedd3575765082e14584fb76 366 Hamap MF_01376 2-aminoethylphosphonate--pyruvate transaminase [phnW]. 1 366 175.88 T 28-03-2018 IPR012703 2-aminoethylphosphonate--pyruvate transaminase GO:0019700|GO:0047304 KEGG: 00440+2.6.1.37|MetaCyc: PWY-6832 ALX04_RS11070 fb6f3a1ae0b920ee5295b5a4aa7d3a06 252 Pfam PF01487 Type I 3-dehydroquinase 20 243 3.0E-65 T 28-03-2018 IPR001381 3-dehydroquinate dehydratase type I GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 ALX04_RS11070 fb6f3a1ae0b920ee5295b5a4aa7d3a06 252 Hamap MF_00214 3-dehydroquinate dehydratase [aroD]. 18 249 33.993 T 28-03-2018 IPR001381 3-dehydroquinate dehydratase type I GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 ALX04_RS11070 fb6f3a1ae0b920ee5295b5a4aa7d3a06 252 Gene3D G3DSA:3.20.20.70 2 251 7.9E-80 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 ALX04_RS11070 fb6f3a1ae0b920ee5295b5a4aa7d3a06 252 TIGRFAM TIGR01093 aroD: 3-dehydroquinate dehydratase, type I 19 243 2.3E-68 T 28-03-2018 IPR001381 3-dehydroquinate dehydratase type I GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 ALX04_RS11070 fb6f3a1ae0b920ee5295b5a4aa7d3a06 252 SUPERFAMILY SSF51569 5 249 5.13E-74 T 28-03-2018 ALX04_RS08410 c3e71fbec20bd2134905e022de61e664 494 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 23 428 2.3E-105 T 28-03-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 ALX04_RS08410 c3e71fbec20bd2134905e022de61e664 494 PRINTS PR01036 Tetracycline resistance protein TetB signature 310 334 4.1E-6 T 28-03-2018 ALX04_RS08410 c3e71fbec20bd2134905e022de61e664 494 PRINTS PR01036 Tetracycline resistance protein TetB signature 85 107 4.1E-6 T 28-03-2018 ALX04_RS08410 c3e71fbec20bd2134905e022de61e664 494 PRINTS PR01036 Tetracycline resistance protein TetB signature 367 387 4.1E-6 T 28-03-2018 ALX04_RS08410 c3e71fbec20bd2134905e022de61e664 494 PRINTS PR01036 Tetracycline resistance protein TetB signature 146 170 4.1E-6 T 28-03-2018 ALX04_RS08410 c3e71fbec20bd2134905e022de61e664 494 Pfam PF07690 Major Facilitator Superfamily 26 417 5.2E-54 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 ALX04_RS08410 c3e71fbec20bd2134905e022de61e664 494 Gene3D G3DSA:1.20.1250.20 17 206 1.9E-34 T 28-03-2018 ALX04_RS08410 c3e71fbec20bd2134905e022de61e664 494 Gene3D G3DSA:1.20.1250.20 267 494 3.5E-29 T 28-03-2018 ALX04_RS08410 c3e71fbec20bd2134905e022de61e664 494 SUPERFAMILY SSF103473 13 205 3.53E-67 T 28-03-2018 IPR020846 Major facilitator superfamily domain ALX04_RS08410 c3e71fbec20bd2134905e022de61e664 494 SUPERFAMILY SSF103473 456 481 3.53E-67 T 28-03-2018 IPR020846 Major facilitator superfamily domain ALX04_RS08410 c3e71fbec20bd2134905e022de61e664 494 SUPERFAMILY SSF103473 256 427 3.53E-67 T 28-03-2018 IPR020846 Major facilitator superfamily domain ALX04_RS07085 12c743aec412d81bd012cdc0efd80cfc 393 SUPERFAMILY SSF88697 1 70 1.66E-12 T 28-03-2018 IPR015947 PUA-like domain ALX04_RS07085 12c743aec412d81bd012cdc0efd80cfc 393 Gene3D G3DSA:3.30.750.80 72 176 5.6E-18 T 28-03-2018 ALX04_RS07085 12c743aec412d81bd012cdc0efd80cfc 393 Pfam PF10672 S-adenosylmethionine-dependent methyltransferase 165 337 3.1E-14 T 28-03-2018 IPR019614 S-adenosylmethionine-dependent methyltransferase GO:0008168 ALX04_RS07085 12c743aec412d81bd012cdc0efd80cfc 393 SUPERFAMILY SSF53335 97 389 1.32E-38 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase ALX04_RS07085 12c743aec412d81bd012cdc0efd80cfc 393 Gene3D G3DSA:3.40.50.150 178 393 7.6E-13 T 28-03-2018 ALX04_RS07085 12c743aec412d81bd012cdc0efd80cfc 393 Gene3D G3DSA:2.30.130.10 3 65 9.7E-9 T 28-03-2018 IPR002478 PUA domain GO:0003723 ALX04_RS09185 14a78fcde8fbefac1e4684f7bddbfc1d 1112 SUPERFAMILY SSF49899 46 253 2.24E-27 T 28-03-2018 IPR013320 Concanavalin A-like lectin/glucanase domain ALX04_RS09185 14a78fcde8fbefac1e4684f7bddbfc1d 1112 Gene3D G3DSA:3.40.720.10 426 752 3.8E-22 T 28-03-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 ALX04_RS09185 14a78fcde8fbefac1e4684f7bddbfc1d 1112 SUPERFAMILY SSF53649 483 728 4.85E-16 T 28-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 ALX04_RS09185 14a78fcde8fbefac1e4684f7bddbfc1d 1112 SUPERFAMILY SSF53649 434 455 4.85E-16 T 28-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 ALX04_RS09185 14a78fcde8fbefac1e4684f7bddbfc1d 1112 Pfam PF01663 Type I phosphodiesterase / nucleotide pyrophosphatase 533 673 3.0E-7 T 28-03-2018 IPR002591 Type I phosphodiesterase/nucleotide pyrophosphatase/phosphate transferase GO:0003824 ALX04_RS09185 14a78fcde8fbefac1e4684f7bddbfc1d 1112 TIGRFAM TIGR01167 LPXTG_anchor: LPXTG cell wall anchor domain 1078 1111 1.6E-6 T 28-03-2018 ALX04_RS09185 14a78fcde8fbefac1e4684f7bddbfc1d 1112 SUPERFAMILY SSF49384 273 379 6.28E-5 T 28-03-2018 IPR008965 Carbohydrate-binding domain GO:0030246 ALX04_RS09185 14a78fcde8fbefac1e4684f7bddbfc1d 1112 Gene3D G3DSA:2.60.120.200 46 258 6.1E-26 T 28-03-2018 ALX04_RS01660 a926edb072ea30e35dcef5b923f1fb3f 246 ProSitePatterns PS01149 Rsu family of pseudouridine synthase signature. 100 114 - T 28-03-2018 IPR018496 Pseudouridine synthase, RsuA/RluB/E/F, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0016866 ALX04_RS01660 a926edb072ea30e35dcef5b923f1fb3f 246 SUPERFAMILY SSF55120 46 237 8.8E-41 T 28-03-2018 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 ALX04_RS01660 a926edb072ea30e35dcef5b923f1fb3f 246 Pfam PF00849 RNA pseudouridylate synthase 62 195 5.7E-18 T 28-03-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 ALX04_RS01660 a926edb072ea30e35dcef5b923f1fb3f 246 TIGRFAM TIGR00093 TIGR00093: pseudouridine synthase 66 230 2.3E-41 T 28-03-2018 IPR000748 Pseudouridine synthase, RsuA/RluB/E/F GO:0001522|GO:0003723|GO:0009451|GO:0016866 ALX04_RS01660 a926edb072ea30e35dcef5b923f1fb3f 246 SUPERFAMILY SSF55174 1 57 3.92E-11 T 28-03-2018 ALX04_RS01660 a926edb072ea30e35dcef5b923f1fb3f 246 Pfam PF01479 S4 domain 1 44 2.7E-8 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 ALX04_RS01660 a926edb072ea30e35dcef5b923f1fb3f 246 SMART SM00363 1 59 1.7E-7 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 ALX04_RS01660 a926edb072ea30e35dcef5b923f1fb3f 246 Gene3D G3DSA:3.10.290.10 1 70 4.3E-14 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 ALX04_RS01660 a926edb072ea30e35dcef5b923f1fb3f 246 Gene3D G3DSA:3.30.2350.10 71 245 4.1E-35 T 28-03-2018 ALX04_RS15045 aca72c2ecc6130ff9cf0c416a5b5192c 329 Gene3D G3DSA:3.30.930.10 58 273 4.1E-47 T 28-03-2018 ALX04_RS15045 aca72c2ecc6130ff9cf0c416a5b5192c 329 Pfam PF03099 Biotin/lipoate A/B protein ligase family 86 214 1.5E-12 T 28-03-2018 IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain GO:0006464 ALX04_RS15045 aca72c2ecc6130ff9cf0c416a5b5192c 329 Gene3D G3DSA:1.10.10.10 3 57 2.9E-8 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS15045 aca72c2ecc6130ff9cf0c416a5b5192c 329 Pfam PF02237 Biotin protein ligase C terminal domain 274 318 5.2E-11 T 28-03-2018 IPR003142 Biotin protein ligase, C-terminal GO:0006464 KEGG: 00780+6.3.4.15|Reactome: R-HSA-196780 ALX04_RS15045 aca72c2ecc6130ff9cf0c416a5b5192c 329 Pfam PF08279 HTH domain 7 58 5.3E-12 T 28-03-2018 IPR013196 Helix-turn-helix, type 11 ALX04_RS15045 aca72c2ecc6130ff9cf0c416a5b5192c 329 SUPERFAMILY SSF50037 276 318 5.49E-6 T 28-03-2018 IPR008988 Transcriptional repressor, C-terminal ALX04_RS15045 aca72c2ecc6130ff9cf0c416a5b5192c 329 TIGRFAM TIGR00121 birA_ligase: biotin--[acetyl-CoA-carboxylase] ligase 83 318 2.1E-42 T 28-03-2018 IPR004408 Biotin--acetyl-CoA-carboxylase ligase GO:0004077|GO:0006464 KEGG: 00780+6.3.4.15|Reactome: R-HSA-196780 ALX04_RS15045 aca72c2ecc6130ff9cf0c416a5b5192c 329 Hamap MF_00978 Bifunctional ligase/repressor BirA [birA]. 6 320 30.862 T 28-03-2018 IPR030855 Bifunctional ligase/repressor BirA GO:0004077|GO:0006355 KEGG: 00780+6.3.4.15 ALX04_RS15045 aca72c2ecc6130ff9cf0c416a5b5192c 329 Gene3D G3DSA:2.30.30.100 274 320 9.1E-12 T 28-03-2018 ALX04_RS15045 aca72c2ecc6130ff9cf0c416a5b5192c 329 SUPERFAMILY SSF55681 71 270 1.21E-43 T 28-03-2018 ALX04_RS15045 aca72c2ecc6130ff9cf0c416a5b5192c 329 SUPERFAMILY SSF46785 8 61 3.68E-9 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS04685 15b3b5e6b405e437af836ee0bb7dab44 78 ProDom PD048972 UPF0154 TRANSMEMBRANE MEMBRANE UNCHARACTERIZED FAMILY YNEF SUPERFAMILY MG335.1 EXPORTED MYCGA5700 27 64 2.0E-16 T 28-03-2018 IPR005359 Protein with unknown function UPF0154 ALX04_RS04685 15b3b5e6b405e437af836ee0bb7dab44 78 Pfam PF03672 Uncharacterised protein family (UPF0154) 12 71 7.1E-30 T 28-03-2018 IPR005359 Protein with unknown function UPF0154 ALX04_RS04685 15b3b5e6b405e437af836ee0bb7dab44 78 Hamap MF_00363 UPF0154 protein . 4 74 20.173 T 28-03-2018 IPR005359 Protein with unknown function UPF0154 ALX04_RS02145 73de7db03ca0c054b26fa07038ad0c95 275 Gene3D G3DSA:3.40.50.720 91 275 8.2E-5 T 28-03-2018 ALX04_RS02145 73de7db03ca0c054b26fa07038ad0c95 275 Pfam PF05368 NmrA-like family 3 212 2.0E-13 T 28-03-2018 IPR008030 NmrA-like domain Reactome: R-HSA-70635 ALX04_RS02145 73de7db03ca0c054b26fa07038ad0c95 275 Gene3D G3DSA:3.40.50.720 1 90 2.5E-10 T 28-03-2018 ALX04_RS02145 73de7db03ca0c054b26fa07038ad0c95 275 SUPERFAMILY SSF51735 3 265 1.18E-38 T 28-03-2018 IPR016040 NAD(P)-binding domain ALX04_RS03580 670bc4c31d43606f123cca6e86a0712e 140 SUPERFAMILY SSF46785 6 133 2.3E-23 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS03580 670bc4c31d43606f123cca6e86a0712e 140 Pfam PF01047 MarR family 28 84 2.4E-7 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 ALX04_RS03580 670bc4c31d43606f123cca6e86a0712e 140 Gene3D G3DSA:1.10.10.10 1 134 2.2E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS03580 670bc4c31d43606f123cca6e86a0712e 140 SMART SM00347 21 120 1.8E-12 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 ALX04_RS03580 670bc4c31d43606f123cca6e86a0712e 140 PRINTS PR00598 Bacterial regulatory protein MarR family signature 44 60 7.0E-7 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 ALX04_RS03580 670bc4c31d43606f123cca6e86a0712e 140 PRINTS PR00598 Bacterial regulatory protein MarR family signature 61 76 7.0E-7 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 ALX04_RS03580 670bc4c31d43606f123cca6e86a0712e 140 PRINTS PR00598 Bacterial regulatory protein MarR family signature 110 130 7.0E-7 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 ALX04_RS03580 670bc4c31d43606f123cca6e86a0712e 140 PRINTS PR00598 Bacterial regulatory protein MarR family signature 80 96 7.0E-7 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 ALX04_RS15285 d79ad6586f69bf4f5eb620ae5aa21d99 518 Pfam PF00117 Glutamine amidotransferase class-I 14 195 1.8E-40 T 28-03-2018 IPR017926 Glutamine amidotransferase ALX04_RS15285 d79ad6586f69bf4f5eb620ae5aa21d99 518 Pfam PF00958 GMP synthase C terminal domain 426 517 6.7E-44 T 28-03-2018 IPR001674 GMP synthase, C-terminal GO:0003922|GO:0005524|GO:0006164|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 ALX04_RS15285 d79ad6586f69bf4f5eb620ae5aa21d99 518 Gene3D G3DSA:3.40.50.620 217 393 5.7E-35 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold ALX04_RS15285 d79ad6586f69bf4f5eb620ae5aa21d99 518 SUPERFAMILY SSF52402 193 411 1.44E-58 T 28-03-2018 ALX04_RS15285 d79ad6586f69bf4f5eb620ae5aa21d99 518 PRINTS PR00096 Glutamine amidotransferase superfamily signature 83 94 6.8E-6 T 28-03-2018 ALX04_RS15285 d79ad6586f69bf4f5eb620ae5aa21d99 518 PRINTS PR00096 Glutamine amidotransferase superfamily signature 56 65 6.8E-6 T 28-03-2018 ALX04_RS15285 d79ad6586f69bf4f5eb620ae5aa21d99 518 PRINTS PR00096 Glutamine amidotransferase superfamily signature 173 186 6.8E-6 T 28-03-2018 ALX04_RS15285 d79ad6586f69bf4f5eb620ae5aa21d99 518 TIGRFAM TIGR00884 guaA_Cterm: GMP synthase (glutamine-hydrolyzing), C-terminal domain 208 518 3.3E-153 T 28-03-2018 IPR001674 GMP synthase, C-terminal GO:0003922|GO:0005524|GO:0006164|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 ALX04_RS15285 d79ad6586f69bf4f5eb620ae5aa21d99 518 Pfam PF02540 NAD synthase 215 288 1.8E-7 T 28-03-2018 IPR022310 NAD/GMP synthase ALX04_RS15285 d79ad6586f69bf4f5eb620ae5aa21d99 518 SUPERFAMILY SSF52317 10 233 3.28E-53 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like ALX04_RS15285 d79ad6586f69bf4f5eb620ae5aa21d99 518 SUPERFAMILY SSF54810 398 518 2.35E-50 T 28-03-2018 ALX04_RS15285 d79ad6586f69bf4f5eb620ae5aa21d99 518 Gene3D G3DSA:3.30.300.10 394 518 7.3E-52 T 28-03-2018 ALX04_RS15285 d79ad6586f69bf4f5eb620ae5aa21d99 518 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 83 99 2.1E-5 T 28-03-2018 ALX04_RS15285 d79ad6586f69bf4f5eb620ae5aa21d99 518 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 12 26 2.1E-5 T 28-03-2018 ALX04_RS15285 d79ad6586f69bf4f5eb620ae5aa21d99 518 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 53 67 2.1E-5 T 28-03-2018 ALX04_RS15285 d79ad6586f69bf4f5eb620ae5aa21d99 518 Gene3D G3DSA:3.40.50.880 7 216 2.7E-49 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like ALX04_RS15285 d79ad6586f69bf4f5eb620ae5aa21d99 518 Hamap MF_00344 GMP synthase [glutamine-hydrolyzing] [guaA]. 9 518 54.049 T 28-03-2018 IPR022955 GMP synthase GO:0003922|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221 ALX04_RS15285 d79ad6586f69bf4f5eb620ae5aa21d99 518 TIGRFAM TIGR00888 guaA_Nterm: GMP synthase (glutamine-hydrolyzing), N-terminal domain 12 200 1.9E-77 T 28-03-2018 IPR004739 GMP synthase, glutamine amidotransferase GO:0003922|GO:0005524|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 ALX04_RS15035 0d95ff616da14c5132dbf2cfbbcc3796 587 Gene3D G3DSA:3.40.50.970 1 190 3.1E-45 T 28-03-2018 ALX04_RS15035 0d95ff616da14c5132dbf2cfbbcc3796 587 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 383 533 3.0E-25 T 28-03-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 ALX04_RS15035 0d95ff616da14c5132dbf2cfbbcc3796 587 SUPERFAMILY SSF52518 359 551 3.28E-43 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold ALX04_RS15035 0d95ff616da14c5132dbf2cfbbcc3796 587 Gene3D G3DSA:3.40.50.1220 191 322 7.8E-33 T 28-03-2018 IPR029035 DHS-like NAD/FAD-binding domain ALX04_RS15035 0d95ff616da14c5132dbf2cfbbcc3796 587 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 195 322 1.4E-30 T 28-03-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 ALX04_RS15035 0d95ff616da14c5132dbf2cfbbcc3796 587 SUPERFAMILY SSF52467 189 356 6.35E-40 T 28-03-2018 IPR029035 DHS-like NAD/FAD-binding domain ALX04_RS15035 0d95ff616da14c5132dbf2cfbbcc3796 587 ProSitePatterns PS00187 Thiamine pyrophosphate enzymes signature. 420 439 - T 28-03-2018 IPR000399 TPP-binding enzyme, conserved site GO:0000287|GO:0030976 ALX04_RS15035 0d95ff616da14c5132dbf2cfbbcc3796 587 Gene3D G3DSA:3.40.50.970 323 539 6.9E-34 T 28-03-2018 ALX04_RS15035 0d95ff616da14c5132dbf2cfbbcc3796 587 SUPERFAMILY SSF52518 3 179 2.7E-47 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold ALX04_RS15035 0d95ff616da14c5132dbf2cfbbcc3796 587 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 7 172 4.2E-46 T 28-03-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 ALX04_RS14165 c4fd688fc8d22b32a4cd57fe9c200991 440 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 153 167 - T 28-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 ALX04_RS14165 c4fd688fc8d22b32a4cd57fe9c200991 440 SUPERFAMILY SSF51246 332 436 1.52E-20 T 28-03-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 ALX04_RS14165 c4fd688fc8d22b32a4cd57fe9c200991 440 Pfam PF00289 Biotin carboxylase, N-terminal domain 1 110 5.9E-43 T 28-03-2018 IPR005481 Biotin carboxylase-like, N-terminal domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599 ALX04_RS14165 c4fd688fc8d22b32a4cd57fe9c200991 440 SMART SM00878 335 434 1.0E-21 T 28-03-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 ALX04_RS14165 c4fd688fc8d22b32a4cd57fe9c200991 440 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 115 319 1.6E-53 T 28-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 ALX04_RS14165 c4fd688fc8d22b32a4cd57fe9c200991 440 Gene3D G3DSA:3.30.1490.20 124 209 3.0E-17 T 28-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 ALX04_RS14165 c4fd688fc8d22b32a4cd57fe9c200991 440 Gene3D G3DSA:3.30.470.20 210 436 1.0E-65 T 28-03-2018 ALX04_RS14165 c4fd688fc8d22b32a4cd57fe9c200991 440 SUPERFAMILY SSF56059 83 329 6.72E-55 T 28-03-2018 ALX04_RS14165 c4fd688fc8d22b32a4cd57fe9c200991 440 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 284 291 - T 28-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 ALX04_RS14165 c4fd688fc8d22b32a4cd57fe9c200991 440 Pfam PF02785 Biotin carboxylase C-terminal domain 346 434 1.1E-19 T 28-03-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 ALX04_RS14165 c4fd688fc8d22b32a4cd57fe9c200991 440 Gene3D G3DSA:3.40.50.20 1 123 4.1E-49 T 28-03-2018 ALX04_RS14165 c4fd688fc8d22b32a4cd57fe9c200991 440 SUPERFAMILY SSF52440 1 113 6.83E-45 T 28-03-2018 IPR016185 Pre-ATP-grasp domain ALX04_RS03000 49bdc00e9bd5c6bfd202a11050a93379 347 SUPERFAMILY SSF50129 1 182 1.31E-41 T 28-03-2018 IPR011032 GroES-like ALX04_RS03000 49bdc00e9bd5c6bfd202a11050a93379 347 SUPERFAMILY SSF51735 150 311 1.27E-32 T 28-03-2018 IPR016040 NAD(P)-binding domain ALX04_RS03000 49bdc00e9bd5c6bfd202a11050a93379 347 Gene3D G3DSA:3.40.50.720 169 291 1.5E-19 T 28-03-2018 ALX04_RS03000 49bdc00e9bd5c6bfd202a11050a93379 347 SMART SM00829 4 344 0.0033 T 28-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 ALX04_RS03000 49bdc00e9bd5c6bfd202a11050a93379 347 Gene3D G3DSA:3.90.180.10 1 168 2.6E-39 T 28-03-2018 ALX04_RS03000 49bdc00e9bd5c6bfd202a11050a93379 347 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 26 125 2.3E-21 T 28-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 ALX04_RS03000 49bdc00e9bd5c6bfd202a11050a93379 347 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 59 73 - T 28-03-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 ALX04_RS03000 49bdc00e9bd5c6bfd202a11050a93379 347 Pfam PF00107 Zinc-binding dehydrogenase 181 277 9.6E-21 T 28-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 ALX04_RS02470 79757fc98b1b7b100da77dc985b2d146 545 Pfam PF00512 His Kinase A (phospho-acceptor) domain 278 343 3.5E-16 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 ALX04_RS02470 79757fc98b1b7b100da77dc985b2d146 545 SUPERFAMILY SSF158472 224 275 6.02E-6 T 28-03-2018 ALX04_RS02470 79757fc98b1b7b100da77dc985b2d146 545 Gene3D G3DSA:3.30.565.10 348 509 3.0E-38 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain ALX04_RS02470 79757fc98b1b7b100da77dc985b2d146 545 PRINTS PR00344 Bacterial sensor protein C-terminal signature 461 479 4.8E-16 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 ALX04_RS02470 79757fc98b1b7b100da77dc985b2d146 545 PRINTS PR00344 Bacterial sensor protein C-terminal signature 485 498 4.8E-16 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 ALX04_RS02470 79757fc98b1b7b100da77dc985b2d146 545 PRINTS PR00344 Bacterial sensor protein C-terminal signature 426 440 4.8E-16 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 ALX04_RS02470 79757fc98b1b7b100da77dc985b2d146 545 PRINTS PR00344 Bacterial sensor protein C-terminal signature 444 454 4.8E-16 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 ALX04_RS02470 79757fc98b1b7b100da77dc985b2d146 545 SMART SM00304 222 276 1.1E-7 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 ALX04_RS02470 79757fc98b1b7b100da77dc985b2d146 545 SMART SM00388 277 344 1.9E-18 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 ALX04_RS02470 79757fc98b1b7b100da77dc985b2d146 545 SUPERFAMILY SSF47384 260 342 5.89E-18 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 ALX04_RS02470 79757fc98b1b7b100da77dc985b2d146 545 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 392 498 2.6E-23 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain ALX04_RS02470 79757fc98b1b7b100da77dc985b2d146 545 Pfam PF00672 HAMP domain 224 273 1.4E-7 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 ALX04_RS02470 79757fc98b1b7b100da77dc985b2d146 545 SMART SM00387 389 501 2.9E-32 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain ALX04_RS02470 79757fc98b1b7b100da77dc985b2d146 545 SUPERFAMILY SSF55874 334 499 1.7E-41 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain ALX04_RS02470 79757fc98b1b7b100da77dc985b2d146 545 Gene3D G3DSA:1.10.287.130 267 340 1.1E-15 T 28-03-2018 ALX04_RS13570 39231d89645dbeef2feda6ceb06dbb03 278 ProDom PD029816 REPRESSOR OPERON PUR TRANSCRIPTION PURINE TRANSCRIPTIONAL PURR REGULATION DNA-BINDING GLYCOSYLTRANSFERASE 9 73 3.0E-31 T 28-03-2018 IPR015265 Bacterial purine repressor, N-terminal GO:0003677|GO:0006355 ALX04_RS13570 39231d89645dbeef2feda6ceb06dbb03 278 Gene3D G3DSA:3.40.50.2020 74 274 1.1E-29 T 28-03-2018 ALX04_RS13570 39231d89645dbeef2feda6ceb06dbb03 278 TIGRFAM TIGR01743 purR_Bsub: pur operon repressor PurR 4 270 7.8E-115 T 28-03-2018 IPR010078 Pur operon repressor GO:0003677|GO:0045892|GO:0045982 ALX04_RS13570 39231d89645dbeef2feda6ceb06dbb03 278 SUPERFAMILY SSF46785 2 74 7.21E-26 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS13570 39231d89645dbeef2feda6ceb06dbb03 278 Gene3D G3DSA:1.10.10.10 1 73 2.1E-11 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS13570 39231d89645dbeef2feda6ceb06dbb03 278 Pfam PF00156 Phosphoribosyl transferase domain 108 256 1.8E-21 T 28-03-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 ALX04_RS13570 39231d89645dbeef2feda6ceb06dbb03 278 Pfam PF09182 Bacterial purine repressor, N-terminal 4 73 2.1E-30 T 28-03-2018 IPR015265 Bacterial purine repressor, N-terminal GO:0003677|GO:0006355 ALX04_RS13570 39231d89645dbeef2feda6ceb06dbb03 278 SUPERFAMILY SSF53271 91 254 1.85E-35 T 28-03-2018 IPR029057 Phosphoribosyltransferase-like ALX04_RS02765 220e9c7a01968473b06de32f971fc521 311 SUPERFAMILY SSF53850 35 305 3.0E-65 T 28-03-2018 ALX04_RS02765 220e9c7a01968473b06de32f971fc521 311 Pfam PF04069 Substrate binding domain of ABC-type glycine betaine transport system 35 302 2.9E-58 T 28-03-2018 IPR007210 ABC-type glycine betaine transport system, substrate-binding domain GO:0005215|GO:0006810 ALX04_RS02765 220e9c7a01968473b06de32f971fc521 311 Gene3D G3DSA:3.40.190.10 24 186 1.7E-29 T 28-03-2018 ALX04_RS02765 220e9c7a01968473b06de32f971fc521 311 Gene3D G3DSA:3.40.190.10 187 306 3.9E-22 T 28-03-2018 ALX04_RS12465 ac6fd3fd200f0fc79de9108390fd3e96 290 Gene3D G3DSA:1.20.5.460 108 126 9.9E-5 T 28-03-2018 ALX04_RS12465 ac6fd3fd200f0fc79de9108390fd3e96 290 Pfam PF05833 Fibronectin-binding protein A N-terminus (FbpA) 14 148 9.2E-20 T 28-03-2018 ALX04_RS12465 ac6fd3fd200f0fc79de9108390fd3e96 290 Pfam PF05670 Domain of unknown function (DUF814) 164 244 8.1E-18 T 28-03-2018 IPR008532 Domain of unknown function DUF814 ALX04_RS11170 c2416b10b9276c69b6a7fc9319ac3723 482 SUPERFAMILY SSF51445 3 477 2.61E-160 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily ALX04_RS11170 c2416b10b9276c69b6a7fc9319ac3723 482 Pfam PF00232 Glycosyl hydrolase family 1 3 476 3.8E-135 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 ALX04_RS11170 c2416b10b9276c69b6a7fc9319ac3723 482 ProSitePatterns PS00572 Glycosyl hydrolases family 1 active site. 374 382 - T 28-03-2018 IPR018120 Glycoside hydrolase family 1, active site ALX04_RS11170 c2416b10b9276c69b6a7fc9319ac3723 482 ProSitePatterns PS00653 Glycosyl hydrolases family 1 N-terminal signature. 8 22 - T 28-03-2018 IPR033132 Glycosyl hydrolases family 1, N-terminal conserved site ALX04_RS11170 c2416b10b9276c69b6a7fc9319ac3723 482 Gene3D G3DSA:3.20.20.80 1 482 3.3E-150 T 28-03-2018 ALX04_RS11170 c2416b10b9276c69b6a7fc9319ac3723 482 PRINTS PR00131 Glycosyl hydrolase family 1 signature 395 406 3.0E-18 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 ALX04_RS11170 c2416b10b9276c69b6a7fc9319ac3723 482 PRINTS PR00131 Glycosyl hydrolase family 1 signature 374 382 3.0E-18 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 ALX04_RS11170 c2416b10b9276c69b6a7fc9319ac3723 482 PRINTS PR00131 Glycosyl hydrolase family 1 signature 416 433 3.0E-18 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 ALX04_RS11170 c2416b10b9276c69b6a7fc9319ac3723 482 PRINTS PR00131 Glycosyl hydrolase family 1 signature 308 322 3.0E-18 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 ALX04_RS11170 c2416b10b9276c69b6a7fc9319ac3723 482 PRINTS PR00131 Glycosyl hydrolase family 1 signature 441 453 3.0E-18 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 ALX04_RS03635 f54af1657ccdaa8aa8b9c798cee718a3 285 Pfam PF04018 Domain of unknown function (DUF368) 24 241 2.7E-27 T 28-03-2018 IPR007163 Protein of unknown function DUF368 ALX04_RS06265 ed0f965414f30f141f16422217bbd995 567 SUPERFAMILY SSF51445 7 481 2.66E-159 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily ALX04_RS06265 ed0f965414f30f141f16422217bbd995 567 SMART SM00642 17 426 8.8E-154 T 28-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 ALX04_RS06265 ed0f965414f30f141f16422217bbd995 567 Gene3D G3DSA:3.20.20.80 352 480 2.6E-22 T 28-03-2018 ALX04_RS06265 ed0f965414f30f141f16422217bbd995 567 Gene3D G3DSA:3.20.20.470 1 107 6.6E-36 T 28-03-2018 ALX04_RS06265 ed0f965414f30f141f16422217bbd995 567 Gene3D G3DSA:3.20.20.470 172 351 9.5E-41 T 28-03-2018 ALX04_RS06265 ed0f965414f30f141f16422217bbd995 567 SUPERFAMILY SSF51011 487 564 3.92E-14 T 28-03-2018 ALX04_RS06265 ed0f965414f30f141f16422217bbd995 567 Pfam PF00128 Alpha amylase, catalytic domain 32 383 7.2E-121 T 28-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 ALX04_RS06265 ed0f965414f30f141f16422217bbd995 567 Gene3D G3DSA:2.60.40.1180 487 566 1.8E-17 T 28-03-2018 ALX04_RS06265 ed0f965414f30f141f16422217bbd995 567 Pfam PF16657 Maltogenic Amylase, C-terminal domain 487 559 3.0E-11 T 28-03-2018 IPR032091 Maltogenic Amylase, C-terminal ALX04_RS06265 ed0f965414f30f141f16422217bbd995 567 Gene3D G3DSA:3.90.400.10 108 171 2.4E-28 T 28-03-2018 ALX04_RS00425 8bef0f35641b55db1b39f97fb57b9ca7 89 SUPERFAMILY SSF50249 9 86 6.85E-31 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold ALX04_RS00425 8bef0f35641b55db1b39f97fb57b9ca7 89 PRINTS PR00973 Ribosomal protein S17 family signature 28 51 9.2E-12 T 28-03-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 ALX04_RS00425 8bef0f35641b55db1b39f97fb57b9ca7 89 PRINTS PR00973 Ribosomal protein S17 family signature 60 70 9.2E-12 T 28-03-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 ALX04_RS00425 8bef0f35641b55db1b39f97fb57b9ca7 89 PRINTS PR00973 Ribosomal protein S17 family signature 70 77 9.2E-12 T 28-03-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 ALX04_RS00425 8bef0f35641b55db1b39f97fb57b9ca7 89 ProSitePatterns PS00056 Ribosomal protein S17 signature. 60 72 - T 28-03-2018 IPR019979 Ribosomal protein S17, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 ALX04_RS00425 8bef0f35641b55db1b39f97fb57b9ca7 89 TIGRFAM TIGR03635 uS17_bact: ribosomal protein uS17 9 79 2.8E-35 T 28-03-2018 IPR019984 30S ribosomal protein S17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 ALX04_RS00425 8bef0f35641b55db1b39f97fb57b9ca7 89 ProDom PD001295 RIBOSOMAL S17 30S RIBONUCLEOPROTEIN RRNA-BINDING RNA-BINDING 40S S11 S17P S11 8 80 4.0E-36 T 28-03-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 ALX04_RS00425 8bef0f35641b55db1b39f97fb57b9ca7 89 Gene3D G3DSA:2.40.50.140 9 86 2.1E-31 T 28-03-2018 ALX04_RS00425 8bef0f35641b55db1b39f97fb57b9ca7 89 Hamap MF_01345_B 30S ribosomal protein S17 [rpsQ]. 9 84 24.229 T 28-03-2018 IPR019984 30S ribosomal protein S17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 ALX04_RS00425 8bef0f35641b55db1b39f97fb57b9ca7 89 Pfam PF00366 Ribosomal protein S17 14 81 1.7E-31 T 28-03-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 ALX04_RS09905 e9b57b2d0435c20dd0bc38643c6fbe5a 283 Pfam PF02195 ParB-like nuclease domain 29 116 5.6E-22 T 28-03-2018 IPR003115 ParB/Sulfiredoxin ALX04_RS09905 e9b57b2d0435c20dd0bc38643c6fbe5a 283 TIGRFAM TIGR00180 parB_part: ParB/RepB/Spo0J family partition protein 23 200 6.7E-53 T 28-03-2018 IPR004437 ParB/RepB/Spo0J partition protein family GO:0003677 ALX04_RS09905 e9b57b2d0435c20dd0bc38643c6fbe5a 283 SMART SM00470 27 117 6.8E-27 T 28-03-2018 IPR003115 ParB/Sulfiredoxin ALX04_RS09905 e9b57b2d0435c20dd0bc38643c6fbe5a 283 Gene3D G3DSA:1.10.10.730 118 165 1.1E-18 T 28-03-2018 ALX04_RS09905 e9b57b2d0435c20dd0bc38643c6fbe5a 283 Gene3D G3DSA:3.90.1530.10 14 117 4.3E-32 T 28-03-2018 ALX04_RS09905 e9b57b2d0435c20dd0bc38643c6fbe5a 283 SUPERFAMILY SSF109709 111 217 9.68E-30 T 28-03-2018 ALX04_RS09905 e9b57b2d0435c20dd0bc38643c6fbe5a 283 TIGRFAM TIGR04285 nucleoid_noc: nucleoid occlusion protein 25 276 2.3E-107 T 28-03-2018 IPR023705 Nucleoid occlusion protein ALX04_RS09905 e9b57b2d0435c20dd0bc38643c6fbe5a 283 SUPERFAMILY SSF110849 21 121 4.45E-25 T 28-03-2018 IPR003115 ParB/Sulfiredoxin ALX04_RS04670 af4425f67a1d68101cdcb67f00b847b0 101 SUPERFAMILY SSF82771 16 89 1.96E-10 T 28-03-2018 IPR000305 GIY-YIG nuclease superfamily ALX04_RS04670 af4425f67a1d68101cdcb67f00b847b0 101 Gene3D G3DSA:3.40.1440.10 4 95 7.5E-7 T 28-03-2018 IPR000305 GIY-YIG nuclease superfamily ALX04_RS04670 af4425f67a1d68101cdcb67f00b847b0 101 Pfam PF01541 GIY-YIG catalytic domain 16 90 3.8E-16 T 28-03-2018 IPR000305 GIY-YIG nuclease superfamily ALX04_RS06960 1127f090973f499f1409e2696e94cb22 62 SUPERFAMILY SSF46955 10 59 2.38E-5 T 28-03-2018 IPR009061 Putative DNA-binding domain ALX04_RS06960 1127f090973f499f1409e2696e94cb22 62 Gene3D G3DSA:1.10.10.10 11 62 2.3E-7 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS00445 8cf43bf281c0796a8f3e0257165ed69a 61 Pfam PF00253 Ribosomal protein S14p/S29e 14 60 3.0E-22 T 28-03-2018 IPR001209 Ribosomal protein S14 GO:0003735|GO:0005622|GO:0005840|GO:0006412 ALX04_RS00445 8cf43bf281c0796a8f3e0257165ed69a 61 SUPERFAMILY SSF57716 4 61 6.42E-20 T 28-03-2018 ALX04_RS00445 8cf43bf281c0796a8f3e0257165ed69a 61 ProSitePatterns PS00527 Ribosomal protein S14 signature. 23 45 - T 28-03-2018 IPR018271 Ribosomal protein S14, conserved site GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 ALX04_RS00445 8cf43bf281c0796a8f3e0257165ed69a 61 Hamap MF_01364_B 30S ribosomal protein S14 type Z [rpsZ]. 1 61 24.618 T 28-03-2018 IPR023053 Ribosomal protein S14, type Z ALX04_RS00445 8cf43bf281c0796a8f3e0257165ed69a 61 Gene3D G3DSA:4.10.830.10 1 61 5.4E-20 T 28-03-2018 ALX04_RS11040 ab629e23ef1fc501b0e3dde3d4c1402f 344 Pfam PF01263 Aldose 1-epimerase 20 339 1.3E-65 T 28-03-2018 IPR008183 Aldose 1-/Glucose-6-phosphate 1-epimerase GO:0005975|GO:0016853 ALX04_RS11040 ab629e23ef1fc501b0e3dde3d4c1402f 344 SUPERFAMILY SSF74650 7 340 2.32E-83 T 28-03-2018 IPR011013 Galactose mutarotase-like domain GO:0003824|GO:0005975|GO:0030246 ALX04_RS11040 ab629e23ef1fc501b0e3dde3d4c1402f 344 Gene3D G3DSA:2.70.98.10 7 342 1.6E-75 T 28-03-2018 IPR014718 Glycoside hydrolase-type carbohydrate-binding GO:0030246 ALX04_RS14995 eab33d720a2a89e8bae81118c18508d3 718 Pfam PF02503 Polyphosphate kinase middle domain 123 320 1.8E-65 T 28-03-2018 IPR024953 Polyphosphate kinase middle domain KEGG: 00190+2.7.4.1 ALX04_RS14995 eab33d720a2a89e8bae81118c18508d3 718 Gene3D G3DSA:3.30.870.10 499 685 1.7E-34 T 28-03-2018 ALX04_RS14995 eab33d720a2a89e8bae81118c18508d3 718 Gene3D G3DSA:3.30.1840.10 114 299 2.1E-63 T 28-03-2018 IPR024953 Polyphosphate kinase middle domain KEGG: 00190+2.7.4.1 ALX04_RS14995 eab33d720a2a89e8bae81118c18508d3 718 SUPERFAMILY SSF56024 316 495 2.04E-56 T 28-03-2018 ALX04_RS14995 eab33d720a2a89e8bae81118c18508d3 718 SUPERFAMILY SSF140356 6 110 4.05E-38 T 28-03-2018 IPR025198 Polyphosphate kinase N-terminal domain KEGG: 00190+2.7.4.1 ALX04_RS14995 eab33d720a2a89e8bae81118c18508d3 718 Pfam PF13090 Polyphosphate kinase C-terminal domain 329 675 3.6E-152 T 28-03-2018 IPR025200 Polyphosphate kinase C-terminal domain KEGG: 00190+2.7.4.1 ALX04_RS14995 eab33d720a2a89e8bae81118c18508d3 718 SUPERFAMILY SSF143724 112 313 1.49E-57 T 28-03-2018 ALX04_RS14995 eab33d720a2a89e8bae81118c18508d3 718 TIGRFAM TIGR03705 poly_P_kin: polyphosphate kinase 1 8 676 5.0E-279 T 28-03-2018 IPR003414 Polyphosphate kinase GO:0006799|GO:0008976|GO:0009358 KEGG: 00190+2.7.4.1 ALX04_RS14995 eab33d720a2a89e8bae81118c18508d3 718 Gene3D G3DSA:1.20.58.310 11 113 9.3E-37 T 28-03-2018 ALX04_RS14995 eab33d720a2a89e8bae81118c18508d3 718 Pfam PF13089 Polyphosphate kinase N-terminal domain 9 114 1.5E-38 T 28-03-2018 IPR025198 Polyphosphate kinase N-terminal domain KEGG: 00190+2.7.4.1 ALX04_RS14995 eab33d720a2a89e8bae81118c18508d3 718 Hamap MF_00347 Polyphosphate kinase [ppk]. 7 680 28.844 T 28-03-2018 IPR003414 Polyphosphate kinase GO:0006799|GO:0008976|GO:0009358 KEGG: 00190+2.7.4.1 ALX04_RS14995 eab33d720a2a89e8bae81118c18508d3 718 PIRSF PIRSF015589 1 697 8.1E-283 T 28-03-2018 IPR003414 Polyphosphate kinase GO:0006799|GO:0008976|GO:0009358 KEGG: 00190+2.7.4.1 ALX04_RS14995 eab33d720a2a89e8bae81118c18508d3 718 Gene3D G3DSA:3.30.870.10 313 498 3.1E-18 T 28-03-2018 ALX04_RS14995 eab33d720a2a89e8bae81118c18508d3 718 SUPERFAMILY SSF56024 499 680 1.1E-67 T 28-03-2018 ALX04_RS04195 1046afafe1b8eecea65cc4230206400f 202 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 142 174 2.3E-9 T 28-03-2018 IPR001451 Hexapeptide repeat ALX04_RS04195 1046afafe1b8eecea65cc4230206400f 202 Gene3D G3DSA:2.160.10.10 2 202 1.3E-50 T 28-03-2018 ALX04_RS04195 1046afafe1b8eecea65cc4230206400f 202 Pfam PF14602 Hexapeptide repeat of succinyl-transferase 74 110 0.024 T 28-03-2018 IPR001451 Hexapeptide repeat ALX04_RS04195 1046afafe1b8eecea65cc4230206400f 202 Pfam PF12464 Maltose acetyltransferase 9 58 3.3E-8 T 28-03-2018 IPR024688 Maltose/galactoside acetyltransferase GO:0016407 ALX04_RS04195 1046afafe1b8eecea65cc4230206400f 202 SMART SM01266 5 59 6.0E-13 T 28-03-2018 IPR024688 Maltose/galactoside acetyltransferase GO:0016407 ALX04_RS04195 1046afafe1b8eecea65cc4230206400f 202 SUPERFAMILY SSF51161 2 198 6.93E-53 T 28-03-2018 IPR011004 Trimeric LpxA-like ALX04_RS04195 1046afafe1b8eecea65cc4230206400f 202 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 150 178 - T 28-03-2018 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 ALX04_RS04320 be1ae5efd85b77b29ade26982a8083a8 129 Gene3D G3DSA:1.10.10.10 86 126 0.046 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS04320 be1ae5efd85b77b29ade26982a8083a8 129 SMART SM00345 14 73 2.8E-17 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 ALX04_RS04320 be1ae5efd85b77b29ade26982a8083a8 129 SUPERFAMILY SSF46785 5 77 1.72E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS04320 be1ae5efd85b77b29ade26982a8083a8 129 Gene3D G3DSA:1.10.10.10 3 81 5.8E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS04320 be1ae5efd85b77b29ade26982a8083a8 129 Pfam PF00392 Bacterial regulatory proteins, gntR family 11 73 3.1E-15 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 ALX04_RS08060 8e7d2ccba43c6a0ebda3dd7fb4e4cc76 574 Gene3D G3DSA:2.60.40.10 1 128 2.1E-26 T 28-03-2018 IPR013783 Immunoglobulin-like fold ALX04_RS08060 8e7d2ccba43c6a0ebda3dd7fb4e4cc76 574 SMART SM00642 142 502 1.2E-107 T 28-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 ALX04_RS08060 8e7d2ccba43c6a0ebda3dd7fb4e4cc76 574 SUPERFAMILY SSF81296 1 111 1.96E-13 T 28-03-2018 IPR014756 Immunoglobulin E-set ALX04_RS08060 8e7d2ccba43c6a0ebda3dd7fb4e4cc76 574 SUPERFAMILY SSF51445 68 506 3.02E-117 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily ALX04_RS08060 8e7d2ccba43c6a0ebda3dd7fb4e4cc76 574 Pfam PF00128 Alpha amylase, catalytic domain 176 474 1.6E-64 T 28-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 ALX04_RS08060 8e7d2ccba43c6a0ebda3dd7fb4e4cc76 574 Gene3D G3DSA:3.20.20.80 130 507 5.1E-108 T 28-03-2018 ALX04_RS08060 8e7d2ccba43c6a0ebda3dd7fb4e4cc76 574 Pfam PF02903 Alpha amylase, N-terminal ig-like domain 1 124 1.2E-25 T 28-03-2018 IPR004185 Glycoside hydrolase, family 13, N-terminal Ig-like domain GO:0004553|GO:0005975 ALX04_RS10400 81e6bb89300e1bf3e400ba7ae526ac4a 103 Pfam PF01883 Iron-sulfur cluster assembly protein 6 79 1.1E-18 T 28-03-2018 IPR002744 MIP18 family-like ALX04_RS10400 81e6bb89300e1bf3e400ba7ae526ac4a 103 Gene3D G3DSA:3.30.300.130 2 101 6.1E-27 T 28-03-2018 IPR034904 Fe-S cluster assembly domain ALX04_RS10400 81e6bb89300e1bf3e400ba7ae526ac4a 103 SUPERFAMILY SSF117916 2 100 4.9E-30 T 28-03-2018 IPR034904 Fe-S cluster assembly domain ALX04_RS11645 7ad7d1fe10473a6d94f400732fc6e194 538 Gene3D G3DSA:3.90.76.10 47 168 7.0E-28 T 28-03-2018 ALX04_RS11645 7ad7d1fe10473a6d94f400732fc6e194 538 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 73 454 1.5E-71 T 28-03-2018 IPR000914 Solute-binding protein family 5 domain ALX04_RS11645 7ad7d1fe10473a6d94f400732fc6e194 538 Gene3D G3DSA:3.10.105.10 304 510 1.6E-45 T 28-03-2018 ALX04_RS11645 7ad7d1fe10473a6d94f400732fc6e194 538 SUPERFAMILY SSF53850 24 532 3.68E-110 T 28-03-2018 ALX04_RS11645 7ad7d1fe10473a6d94f400732fc6e194 538 PIRSF PIRSF002741 4 538 2.8E-91 T 28-03-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 ALX04_RS11645 7ad7d1fe10473a6d94f400732fc6e194 538 Gene3D G3DSA:3.40.190.10 169 303 5.9E-30 T 28-03-2018 ALX04_RS04560 089bf3fedc458d92a7d80f6404cf075e 432 Gene3D G3DSA:3.65.10.10 22 220 1.8E-50 T 28-03-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 ALX04_RS04560 089bf3fedc458d92a7d80f6404cf075e 432 ProSitePatterns PS00104 EPSP synthase signature 1. 89 103 - T 28-03-2018 IPR023193 3-phosphoshikimate 1-carboxyvinyltransferase, conserved site KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 ALX04_RS04560 089bf3fedc458d92a7d80f6404cf075e 432 Pfam PF00275 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) 8 425 1.9E-113 T 28-03-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 ALX04_RS04560 089bf3fedc458d92a7d80f6404cf075e 432 Hamap MF_00210 3-phosphoshikimate 1-carboxyvinyltransferase [aroA]. 11 431 31.716 T 28-03-2018 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866|GO:0009073 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 ALX04_RS04560 089bf3fedc458d92a7d80f6404cf075e 432 SUPERFAMILY SSF55205 5 428 2.45E-122 T 28-03-2018 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 ALX04_RS04560 089bf3fedc458d92a7d80f6404cf075e 432 Gene3D G3DSA:3.65.10.10 221 432 6.6E-49 T 28-03-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 ALX04_RS04560 089bf3fedc458d92a7d80f6404cf075e 432 ProSitePatterns PS00885 EPSP synthase signature 2. 340 358 - T 28-03-2018 IPR023193 3-phosphoshikimate 1-carboxyvinyltransferase, conserved site KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 ALX04_RS04560 089bf3fedc458d92a7d80f6404cf075e 432 PIRSF PIRSF000505 2 432 2.7E-116 T 28-03-2018 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866|GO:0009073 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 ALX04_RS04560 089bf3fedc458d92a7d80f6404cf075e 432 TIGRFAM TIGR01356 aroA: 3-phosphoshikimate 1-carboxyvinyltransferase 15 429 6.6E-122 T 28-03-2018 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866|GO:0009073 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 ALX04_RS07055 df79963c27fd1955b1839768316847f4 587 Gene3D G3DSA:3.40.50.300 344 580 1.7E-63 T 28-03-2018 ALX04_RS07055 df79963c27fd1955b1839768316847f4 587 SMART SM00382 372 553 1.3E-15 T 28-03-2018 IPR003593 AAA+ ATPase domain ALX04_RS07055 df79963c27fd1955b1839768316847f4 587 SUPERFAMILY SSF90123 24 332 4.19E-69 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 ALX04_RS07055 df79963c27fd1955b1839768316847f4 587 ProSitePatterns PS00211 ABC transporters family signature. 485 499 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 ALX04_RS07055 df79963c27fd1955b1839768316847f4 587 Gene3D G3DSA:1.20.1560.10 3 335 2.1E-64 T 28-03-2018 ALX04_RS07055 df79963c27fd1955b1839768316847f4 587 Pfam PF00005 ABC transporter 363 513 5.3E-34 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 ALX04_RS07055 df79963c27fd1955b1839768316847f4 587 SUPERFAMILY SSF52540 345 584 4.0E-73 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase ALX04_RS07055 df79963c27fd1955b1839768316847f4 587 Pfam PF00664 ABC transporter transmembrane region 37 303 2.0E-43 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 ALX04_RS12770 075b7750ef17b321e7044b0698fd622e 464 TIGRFAM TIGR01197 nramp: metal ion transporter, metal ion (Mn2+/Fe2+) transporter (Nramp) family 47 428 1.4E-110 T 28-03-2018 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-425410 ALX04_RS12770 075b7750ef17b321e7044b0698fd622e 464 PRINTS PR00447 Natural resistance-associated macrophage protein signature 128 154 2.2E-59 T 28-03-2018 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-425410 ALX04_RS12770 075b7750ef17b321e7044b0698fd622e 464 PRINTS PR00447 Natural resistance-associated macrophage protein signature 181 202 2.2E-59 T 28-03-2018 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-425410 ALX04_RS12770 075b7750ef17b321e7044b0698fd622e 464 PRINTS PR00447 Natural resistance-associated macrophage protein signature 342 361 2.2E-59 T 28-03-2018 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-425410 ALX04_RS12770 075b7750ef17b321e7044b0698fd622e 464 PRINTS PR00447 Natural resistance-associated macrophage protein signature 233 256 2.2E-59 T 28-03-2018 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-425410 ALX04_RS12770 075b7750ef17b321e7044b0698fd622e 464 PRINTS PR00447 Natural resistance-associated macrophage protein signature 370 387 2.2E-59 T 28-03-2018 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-425410 ALX04_RS12770 075b7750ef17b321e7044b0698fd622e 464 PRINTS PR00447 Natural resistance-associated macrophage protein signature 156 175 2.2E-59 T 28-03-2018 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-425410 ALX04_RS12770 075b7750ef17b321e7044b0698fd622e 464 PRINTS PR00447 Natural resistance-associated macrophage protein signature 404 423 2.2E-59 T 28-03-2018 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-425410 ALX04_RS12770 075b7750ef17b321e7044b0698fd622e 464 Hamap MF_00221 Divalent metal cation transporter MntH [mntH]. 40 460 38.871 T 28-03-2018 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-425410 ALX04_RS12770 075b7750ef17b321e7044b0698fd622e 464 Pfam PF01566 Natural resistance-associated macrophage protein 69 434 6.8E-119 T 28-03-2018 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-425410 ALX04_RS12670 9738b433179e5ec821a312f2e7373414 303 SUPERFAMILY SSF53686 3 298 4.45E-85 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme ALX04_RS12670 9738b433179e5ec821a312f2e7373414 303 ProSitePatterns PS00901 Cysteine synthase/cystathionine beta-synthase P-phosphate attachment site. 31 49 - T 28-03-2018 IPR001216 Cysteine synthase/cystathionine beta-synthase, pyridoxal-phosphate attachment site GO:0006535 ALX04_RS12670 9738b433179e5ec821a312f2e7373414 303 Gene3D G3DSA:3.40.50.1100 39 137 3.5E-30 T 28-03-2018 ALX04_RS12670 9738b433179e5ec821a312f2e7373414 303 Gene3D G3DSA:3.40.50.1100 138 303 1.2E-50 T 28-03-2018 ALX04_RS12670 9738b433179e5ec821a312f2e7373414 303 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 8 290 1.5E-60 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme ALX04_RS12870 3887188c014e60d1d57b48550f9359a5 685 Gene3D G3DSA:2.60.40.740 305 552 3.7E-5 T 28-03-2018 ALX04_RS12870 3887188c014e60d1d57b48550f9359a5 685 SUPERFAMILY SSF49899 235 284 2.01E-13 T 28-03-2018 IPR013320 Concanavalin A-like lectin/glucanase domain ALX04_RS12870 3887188c014e60d1d57b48550f9359a5 685 SUPERFAMILY SSF49899 63 208 2.01E-13 T 28-03-2018 IPR013320 Concanavalin A-like lectin/glucanase domain ALX04_RS12870 3887188c014e60d1d57b48550f9359a5 685 Gene3D G3DSA:2.60.120.200 40 258 1.3E-19 T 28-03-2018 ALX04_RS07790 7f2071d9d4565e545fc6c46290fbf78a 1249 Gene3D G3DSA:1.10.486.10 627 787 2.4E-35 T 28-03-2018 ALX04_RS07790 7f2071d9d4565e545fc6c46290fbf78a 1249 Pfam PF00580 UvrD/REP helicase N-terminal domain 8 463 4.6E-72 T 28-03-2018 IPR034739 UvrD/AddA helicase, N-terminal GO:0005524 ALX04_RS07790 7f2071d9d4565e545fc6c46290fbf78a 1249 Gene3D G3DSA:3.40.50.300 1 475 3.7E-55 T 28-03-2018 ALX04_RS07790 7f2071d9d4565e545fc6c46290fbf78a 1249 Gene3D G3DSA:3.40.50.300 476 626 4.8E-14 T 28-03-2018 ALX04_RS07790 7f2071d9d4565e545fc6c46290fbf78a 1249 Gene3D G3DSA:3.90.320.10 1014 1242 2.4E-33 T 28-03-2018 IPR011604 Exonuclease, phage-type/RecB, C-terminal GO:0003677|GO:0004518 ALX04_RS07790 7f2071d9d4565e545fc6c46290fbf78a 1249 Hamap MF_01451 ATP-dependent helicase/nuclease subunit A [addA]. 4 1248 18.686 T 28-03-2018 IPR014152 DNA helicase subunit AddA GO:0004003|GO:0006302 ALX04_RS07790 7f2071d9d4565e545fc6c46290fbf78a 1249 SUPERFAMILY SSF52540 5 74 2.81E-113 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase ALX04_RS07790 7f2071d9d4565e545fc6c46290fbf78a 1249 SUPERFAMILY SSF52540 873 900 2.81E-113 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase ALX04_RS07790 7f2071d9d4565e545fc6c46290fbf78a 1249 SUPERFAMILY SSF52540 102 188 2.81E-113 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase ALX04_RS07790 7f2071d9d4565e545fc6c46290fbf78a 1249 SUPERFAMILY SSF52540 350 841 2.81E-113 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase ALX04_RS07790 7f2071d9d4565e545fc6c46290fbf78a 1249 SUPERFAMILY SSF52980 1025 1240 4.34E-28 T 28-03-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 ALX04_RS07790 7f2071d9d4565e545fc6c46290fbf78a 1249 Pfam PF12705 PD-(D/E)XK nuclease superfamily 1075 1240 2.4E-9 T 28-03-2018 ALX04_RS07790 7f2071d9d4565e545fc6c46290fbf78a 1249 Pfam PF13361 UvrD-like helicase C-terminal domain 473 893 9.5E-29 T 28-03-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 ALX04_RS07790 7f2071d9d4565e545fc6c46290fbf78a 1249 TIGRFAM TIGR02785 addA_Gpos: helicase-exonuclease AddAB, AddA subunit 6 1247 0.0 T 28-03-2018 IPR014152 DNA helicase subunit AddA GO:0004003|GO:0006302 ALX04_RS06365 3f2f35d3b6170591217209babfdf79c4 343 Pfam PF09383 NIL domain 267 339 1.3E-20 T 28-03-2018 IPR018449 NIL domain ALX04_RS06365 3f2f35d3b6170591217209babfdf79c4 343 SUPERFAMILY SSF52540 1 240 8.96E-83 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase ALX04_RS06365 3f2f35d3b6170591217209babfdf79c4 343 SMART SM00382 30 218 8.6E-15 T 28-03-2018 IPR003593 AAA+ ATPase domain ALX04_RS06365 3f2f35d3b6170591217209babfdf79c4 343 Gene3D G3DSA:3.40.50.300 1 251 3.6E-74 T 28-03-2018 ALX04_RS06365 3f2f35d3b6170591217209babfdf79c4 343 SMART SM00930 265 340 9.1E-27 T 28-03-2018 IPR018449 NIL domain ALX04_RS06365 3f2f35d3b6170591217209babfdf79c4 343 ProSitePatterns PS00211 ABC transporters family signature. 141 155 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 ALX04_RS06365 3f2f35d3b6170591217209babfdf79c4 343 SUPERFAMILY SSF55021 251 341 8.58E-23 T 28-03-2018 ALX04_RS06365 3f2f35d3b6170591217209babfdf79c4 343 Gene3D G3DSA:3.30.70.260 252 342 3.0E-26 T 28-03-2018 ALX04_RS06365 3f2f35d3b6170591217209babfdf79c4 343 Pfam PF00005 ABC transporter 22 169 2.0E-34 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 ALX04_RS12020 03ff5bdd9b92961576e892e44dcb88f8 238 PRINTS PR00783 Major intrinsic protein family signature 166 188 1.4E-25 T 28-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 ALX04_RS12020 03ff5bdd9b92961576e892e44dcb88f8 238 PRINTS PR00783 Major intrinsic protein family signature 214 234 1.4E-25 T 28-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 ALX04_RS12020 03ff5bdd9b92961576e892e44dcb88f8 238 PRINTS PR00783 Major intrinsic protein family signature 137 155 1.4E-25 T 28-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 ALX04_RS12020 03ff5bdd9b92961576e892e44dcb88f8 238 PRINTS PR00783 Major intrinsic protein family signature 3 22 1.4E-25 T 28-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 ALX04_RS12020 03ff5bdd9b92961576e892e44dcb88f8 238 PRINTS PR00783 Major intrinsic protein family signature 79 98 1.4E-25 T 28-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 ALX04_RS12020 03ff5bdd9b92961576e892e44dcb88f8 238 Gene3D G3DSA:1.20.1080.10 1 238 6.0E-60 T 28-03-2018 IPR023271 Aquaporin-like Reactome: R-HSA-432047 ALX04_RS12020 03ff5bdd9b92961576e892e44dcb88f8 238 Pfam PF00230 Major intrinsic protein 3 229 1.2E-30 T 28-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 ALX04_RS12020 03ff5bdd9b92961576e892e44dcb88f8 238 SUPERFAMILY SSF81338 2 236 2.49E-53 T 28-03-2018 IPR023271 Aquaporin-like Reactome: R-HSA-432047 ALX04_RS05920 03c5412ff72f22d5cee4dc24daea7d61 336 Gene3D G3DSA:3.40.50.2300 62 169 1.0E-26 T 28-03-2018 ALX04_RS05920 03c5412ff72f22d5cee4dc24daea7d61 336 Pfam PF00356 Bacterial regulatory proteins, lacI family 7 52 3.9E-19 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 ALX04_RS05920 03c5412ff72f22d5cee4dc24daea7d61 336 SUPERFAMILY SSF47413 5 63 8.63E-19 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 ALX04_RS05920 03c5412ff72f22d5cee4dc24daea7d61 336 Gene3D G3DSA:3.40.50.2300 170 335 9.1E-39 T 28-03-2018 ALX04_RS05920 03c5412ff72f22d5cee4dc24daea7d61 336 Pfam PF13377 Periplasmic binding protein-like domain 173 332 8.3E-30 T 28-03-2018 ALX04_RS05920 03c5412ff72f22d5cee4dc24daea7d61 336 ProSitePatterns PS00356 LacI-type HTH domain signature. 8 26 - T 28-03-2018 ALX04_RS05920 03c5412ff72f22d5cee4dc24daea7d61 336 TIGRFAM TIGR01481 ccpA: catabolite control protein A 4 333 2.1E-174 T 28-03-2018 IPR006377 Catabolite control protein A GO:0006355 ALX04_RS05920 03c5412ff72f22d5cee4dc24daea7d61 336 Gene3D G3DSA:1.10.260.40 6 61 1.8E-24 T 28-03-2018 ALX04_RS05920 03c5412ff72f22d5cee4dc24daea7d61 336 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 7 17 9.7E-6 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 ALX04_RS05920 03c5412ff72f22d5cee4dc24daea7d61 336 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 17 27 9.7E-6 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 ALX04_RS05920 03c5412ff72f22d5cee4dc24daea7d61 336 SUPERFAMILY SSF53822 65 334 9.79E-75 T 28-03-2018 IPR028082 Periplasmic binding protein-like I ALX04_RS05920 03c5412ff72f22d5cee4dc24daea7d61 336 SMART SM00354 5 75 3.8E-37 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 ALX04_RS06045 370184fb90dadc0bed4791f17b5ed33a 344 Gene3D G3DSA:3.40.1780.10 1 148 1.3E-40 T 28-03-2018 ALX04_RS06045 370184fb90dadc0bed4791f17b5ed33a 344 Gene3D G3DSA:3.40.1780.10 175 344 1.2E-64 T 28-03-2018 ALX04_RS06045 370184fb90dadc0bed4791f17b5ed33a 344 Hamap MF_00113 S-adenosylmethionine:tRNA ribosyltransferase-isomerase [queA]. 1 344 45.714 T 28-03-2018 IPR003699 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700 ALX04_RS06045 370184fb90dadc0bed4791f17b5ed33a 344 TIGRFAM TIGR00113 queA: S-adenosylmethionine:tRNA ribosyltransferase-isomerase 4 343 5.1E-137 T 28-03-2018 IPR003699 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700 ALX04_RS06045 370184fb90dadc0bed4791f17b5ed33a 344 SUPERFAMILY SSF111337 4 343 1.44E-137 T 28-03-2018 IPR003699 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700 ALX04_RS06045 370184fb90dadc0bed4791f17b5ed33a 344 Pfam PF02547 Queuosine biosynthesis protein 5 343 6.1E-138 T 28-03-2018 IPR003699 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700 ALX04_RS00140 a1eba075d4bc5d81682359d36db90711 493 SUPERFAMILY SSF63418 10 98 1.7E-22 T 28-03-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 ALX04_RS00140 a1eba075d4bc5d81682359d36db90711 493 Hamap MF_00208 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase [murE]. 1 486 34.873 T 28-03-2018 IPR005761 UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase GO:0005524|GO:0005737|GO:0008360|GO:0016881|GO:0051301 ALX04_RS00140 a1eba075d4bc5d81682359d36db90711 493 TIGRFAM TIGR01085 murE: UDP-N-acetylmuramyl-tripeptide synthetase 23 486 1.3E-161 T 28-03-2018 IPR005761 UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase GO:0005524|GO:0005737|GO:0008360|GO:0016881|GO:0051301 ALX04_RS00140 a1eba075d4bc5d81682359d36db90711 493 SUPERFAMILY SSF53623 99 334 2.62E-74 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 ALX04_RS00140 a1eba075d4bc5d81682359d36db90711 493 Pfam PF02875 Mur ligase family, glutamate ligase domain 335 419 9.8E-20 T 28-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 ALX04_RS00140 a1eba075d4bc5d81682359d36db90711 493 Pfam PF01225 Mur ligase family, catalytic domain 25 96 3.4E-12 T 28-03-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 ALX04_RS00140 a1eba075d4bc5d81682359d36db90711 493 Gene3D G3DSA:3.40.1390.10 1 98 5.3E-24 T 28-03-2018 ALX04_RS00140 a1eba075d4bc5d81682359d36db90711 493 Gene3D G3DSA:3.40.1190.10 99 339 8.4E-64 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 ALX04_RS00140 a1eba075d4bc5d81682359d36db90711 493 Pfam PF08245 Mur ligase middle domain 108 315 3.8E-54 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 ALX04_RS00140 a1eba075d4bc5d81682359d36db90711 493 SUPERFAMILY SSF53244 335 486 4.88E-46 T 28-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 ALX04_RS00140 a1eba075d4bc5d81682359d36db90711 493 Gene3D G3DSA:3.90.190.20 341 491 1.2E-47 T 28-03-2018 ALX04_RS00225 5b781cae8773947a4caeeece4abee8f9 215 Gene3D G3DSA:1.10.60.10 72 122 1.4E-21 T 28-03-2018 IPR001367 Iron dependent repressor, metal binding and dimerisation domain GO:0046914|GO:0046983 ALX04_RS00225 5b781cae8773947a4caeeece4abee8f9 215 SUPERFAMILY SSF50037 145 215 4.58E-6 T 28-03-2018 IPR008988 Transcriptional repressor, C-terminal ALX04_RS00225 5b781cae8773947a4caeeece4abee8f9 215 SUPERFAMILY SSF46785 1 61 3.58E-11 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS00225 5b781cae8773947a4caeeece4abee8f9 215 SMART SM00899 142 215 8.5E-10 T 28-03-2018 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 ALX04_RS00225 5b781cae8773947a4caeeece4abee8f9 215 Gene3D G3DSA:1.10.10.10 2 71 7.6E-14 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS00225 5b781cae8773947a4caeeece4abee8f9 215 Pfam PF04023 FeoA domain 142 215 4.1E-12 T 28-03-2018 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 ALX04_RS00225 5b781cae8773947a4caeeece4abee8f9 215 SUPERFAMILY SSF47979 62 138 9.16E-26 T 28-03-2018 IPR001367 Iron dependent repressor, metal binding and dimerisation domain GO:0046914|GO:0046983 ALX04_RS00225 5b781cae8773947a4caeeece4abee8f9 215 SMART SM00529 23 122 2.4E-35 T 28-03-2018 IPR022689 Iron dependent repressor GO:0003700|GO:0006355|GO:0046914 ALX04_RS00225 5b781cae8773947a4caeeece4abee8f9 215 Pfam PF02742 Iron dependent repressor, metal binding and dimerisation domain 62 131 1.7E-27 T 28-03-2018 IPR001367 Iron dependent repressor, metal binding and dimerisation domain GO:0046914|GO:0046983 ALX04_RS00225 5b781cae8773947a4caeeece4abee8f9 215 Pfam PF01325 Iron dependent repressor, N-terminal DNA binding domain 2 58 1.2E-14 T 28-03-2018 IPR022687 DTXR-type HTH domain GO:0003677 ALX04_RS00225 5b781cae8773947a4caeeece4abee8f9 215 Gene3D G3DSA:2.30.30.90 123 215 7.6E-15 T 28-03-2018 ALX04_RS08890 b85183c0bd4821b841586dc2238830d3 193 SUPERFAMILY SSF102114 47 115 4.71E-8 T 28-03-2018 ALX04_RS08890 b85183c0bd4821b841586dc2238830d3 193 PIRSF PIRSF000368 16 191 4.8E-70 T 28-03-2018 IPR012837 Ribonucleoside-triphosphate reductase activating, anaerobic GO:0005737|GO:0043365|GO:0051539|GO:0055114 ALX04_RS08890 b85183c0bd4821b841586dc2238830d3 193 TIGRFAM TIGR02491 NrdG: anaerobic ribonucleoside-triphosphate reductase activating protein 26 176 7.2E-54 T 28-03-2018 IPR012837 Ribonucleoside-triphosphate reductase activating, anaerobic GO:0005737|GO:0043365|GO:0051539|GO:0055114 ALX04_RS08890 b85183c0bd4821b841586dc2238830d3 193 Pfam PF13353 4Fe-4S single cluster domain 35 174 2.2E-50 T 28-03-2018 ALX04_RS08890 b85183c0bd4821b841586dc2238830d3 193 Gene3D G3DSA:3.80.30.10 84 189 5.0E-10 T 28-03-2018 ALX04_RS10325 b35cc75483c45cd5a8b967d8353b1437 170 ProSitePatterns PS00794 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase signature. 92 103 - T 28-03-2018 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 ALX04_RS10325 b35cc75483c45cd5a8b967d8353b1437 170 Pfam PF01288 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) 9 136 8.8E-36 T 28-03-2018 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 ALX04_RS10325 b35cc75483c45cd5a8b967d8353b1437 170 TIGRFAM TIGR01498 folK: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase 8 136 9.6E-41 T 28-03-2018 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 ALX04_RS10325 b35cc75483c45cd5a8b967d8353b1437 170 Gene3D G3DSA:3.30.70.560 4 168 2.6E-52 T 28-03-2018 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 ALX04_RS10325 b35cc75483c45cd5a8b967d8353b1437 170 SUPERFAMILY SSF55083 7 157 1.57E-46 T 28-03-2018 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 ALX04_RS03205 095ebba787aeba7edebc8ba0c653b186 88 Pfam PF04226 Transglycosylase associated protein 33 76 8.0E-7 T 28-03-2018 IPR007341 Transglycosylase-associated protein GO:0016021 ALX04_RS03225 2bb80e09ba979a2a77f61ea9b46b03d1 64 SUPERFAMILY SSF55331 2 60 2.09E-17 T 28-03-2018 IPR014347 Tautomerase/MIF superfamily ALX04_RS03225 2bb80e09ba979a2a77f61ea9b46b03d1 64 TIGRFAM TIGR00013 taut: 4-oxalocrotonate tautomerase family enzyme 1 60 6.3E-18 T 28-03-2018 IPR018191 4-oxalocrotonate tautomerase, Pseudomonas-type GO:0006725|GO:0016853 ALX04_RS03225 2bb80e09ba979a2a77f61ea9b46b03d1 64 Gene3D G3DSA:3.30.429.10 2 64 4.9E-16 T 28-03-2018 ALX04_RS03225 2bb80e09ba979a2a77f61ea9b46b03d1 64 Pfam PF01361 Tautomerase enzyme 2 60 1.1E-19 T 28-03-2018 IPR004370 4-oxalocrotonate tautomerase GO:0006725|GO:0016853 ALX04_RS06340 304d95ccccc5ea1cc236528f28686b66 342 Pfam PF13602 Zinc-binding dehydrogenase 195 336 9.1E-16 T 28-03-2018 ALX04_RS06340 304d95ccccc5ea1cc236528f28686b66 342 Gene3D G3DSA:3.40.50.720 165 273 4.6E-15 T 28-03-2018 ALX04_RS06340 304d95ccccc5ea1cc236528f28686b66 342 TIGRFAM TIGR02817 adh_fam_1: zinc-binding alcohol dehydrogenase family protein 4 337 4.7E-100 T 28-03-2018 IPR014182 Alcohol dehydrogenase, zinc-binding type 1 GO:0008270 ALX04_RS06340 304d95ccccc5ea1cc236528f28686b66 342 SUPERFAMILY SSF51735 119 280 3.6E-32 T 28-03-2018 IPR016040 NAD(P)-binding domain ALX04_RS06340 304d95ccccc5ea1cc236528f28686b66 342 ProSitePatterns PS01162 Quinone oxidoreductase / zeta-crystallin signature. 152 173 - T 28-03-2018 IPR002364 Quinone oxidoreductase/zeta-crystallin, conserved site GO:0008270|GO:0016491 ALX04_RS06340 304d95ccccc5ea1cc236528f28686b66 342 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 34 91 9.0E-5 T 28-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 ALX04_RS06340 304d95ccccc5ea1cc236528f28686b66 342 Gene3D G3DSA:3.90.180.10 1 164 3.3E-36 T 28-03-2018 ALX04_RS06340 304d95ccccc5ea1cc236528f28686b66 342 SMART SM00829 15 336 8.9E-10 T 28-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 ALX04_RS06340 304d95ccccc5ea1cc236528f28686b66 342 SUPERFAMILY SSF50129 14 140 1.13E-26 T 28-03-2018 IPR011032 GroES-like ALX04_RS12800 b1ea53b4a28a1c79c422a3ba454418ce 458 SUPERFAMILY SSF55874 298 456 5.37E-35 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain ALX04_RS12800 b1ea53b4a28a1c79c422a3ba454418ce 458 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 350 457 6.3E-19 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain ALX04_RS12800 b1ea53b4a28a1c79c422a3ba454418ce 458 Pfam PF00512 His Kinase A (phospho-acceptor) domain 243 306 2.1E-16 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 ALX04_RS12800 b1ea53b4a28a1c79c422a3ba454418ce 458 SUPERFAMILY SSF47384 225 307 1.06E-17 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 ALX04_RS12800 b1ea53b4a28a1c79c422a3ba454418ce 458 Gene3D G3DSA:1.10.287.130 232 294 4.0E-16 T 28-03-2018 ALX04_RS12800 b1ea53b4a28a1c79c422a3ba454418ce 458 PRINTS PR00344 Bacterial sensor protein C-terminal signature 420 438 5.0E-10 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 ALX04_RS12800 b1ea53b4a28a1c79c422a3ba454418ce 458 PRINTS PR00344 Bacterial sensor protein C-terminal signature 385 399 5.0E-10 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 ALX04_RS12800 b1ea53b4a28a1c79c422a3ba454418ce 458 PRINTS PR00344 Bacterial sensor protein C-terminal signature 444 457 5.0E-10 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 ALX04_RS12800 b1ea53b4a28a1c79c422a3ba454418ce 458 PRINTS PR00344 Bacterial sensor protein C-terminal signature 403 413 5.0E-10 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 ALX04_RS12800 b1ea53b4a28a1c79c422a3ba454418ce 458 SMART SM00387 348 458 2.4E-26 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain ALX04_RS12800 b1ea53b4a28a1c79c422a3ba454418ce 458 SMART SM00388 241 308 8.3E-18 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 ALX04_RS12800 b1ea53b4a28a1c79c422a3ba454418ce 458 Gene3D G3DSA:3.30.565.10 295 458 9.4E-32 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain ALX04_RS00560 031a54ec8ef005e3759a7966fd3472fe 266 Pfam PF02361 Cobalt transport protein 15 237 2.3E-53 T 28-03-2018 IPR003339 ABC/ECF transporter, transmembrane component ALX04_RS00560 031a54ec8ef005e3759a7966fd3472fe 266 Hamap MF_01461 Energy-coupling factor transporter transmembrane protein EcfT [ecfT]. 2 266 37.679 T 28-03-2018 IPR024919 ECF transporter transmembrane protein EcfT GO:0005215|GO:0006810|GO:0016021 ALX04_RS10245 e900b5fb4fe132b182135a295d2c975f 314 Pfam PF16916 Dimerisation domain of Zinc Transporter 238 305 1.9E-7 T 28-03-2018 IPR027470 Cation efflux protein, cytoplasmic domain ALX04_RS10245 e900b5fb4fe132b182135a295d2c975f 314 Gene3D G3DSA:3.30.70.1350 232 314 1.6E-7 T 28-03-2018 IPR027470 Cation efflux protein, cytoplasmic domain ALX04_RS10245 e900b5fb4fe132b182135a295d2c975f 314 SUPERFAMILY SSF161111 16 233 8.89E-30 T 28-03-2018 ALX04_RS10245 e900b5fb4fe132b182135a295d2c975f 314 SUPERFAMILY SSF160240 237 308 1.09E-8 T 28-03-2018 ALX04_RS10245 e900b5fb4fe132b182135a295d2c975f 314 Gene3D G3DSA:1.20.1510.10 16 231 1.3E-27 T 28-03-2018 ALX04_RS10245 e900b5fb4fe132b182135a295d2c975f 314 Pfam PF01545 Cation efflux family 27 232 1.4E-39 T 28-03-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 ALX04_RS10245 e900b5fb4fe132b182135a295d2c975f 314 TIGRFAM TIGR01297 CDF: cation diffusion facilitator family transporter 101 303 9.6E-34 T 28-03-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 ALX04_RS12705 90eee62a7a908d538673463e0e469406 547 TIGRFAM TIGR02403 trehalose_treC: alpha,alpha-phosphotrehalase 3 544 4.3E-265 T 28-03-2018 IPR012769 Trehalose-6-phosphate hydrolase GO:0005737|GO:0005993|GO:0008788 KEGG: 00500+3.2.1.93 ALX04_RS12705 90eee62a7a908d538673463e0e469406 547 Gene3D G3DSA:3.20.20.80 2 256 5.2E-63 T 28-03-2018 ALX04_RS12705 90eee62a7a908d538673463e0e469406 547 Gene3D G3DSA:3.20.20.80 257 495 1.3E-55 T 28-03-2018 ALX04_RS12705 90eee62a7a908d538673463e0e469406 547 SUPERFAMILY SSF51445 4 468 3.52E-133 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily ALX04_RS12705 90eee62a7a908d538673463e0e469406 547 Pfam PF00128 Alpha amylase, catalytic domain 25 371 3.8E-106 T 28-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 ALX04_RS12705 90eee62a7a908d538673463e0e469406 547 Gene3D G3DSA:2.60.40.1180 496 544 5.3E-7 T 28-03-2018 ALX04_RS12705 90eee62a7a908d538673463e0e469406 547 Pfam PF11941 Domain of unknown function (DUF3459) 455 543 3.6E-7 T 28-03-2018 IPR022567 Glycosyl hydrolase, C-terminal (DUF3459) ALX04_RS12705 90eee62a7a908d538673463e0e469406 547 SUPERFAMILY SSF51011 472 545 9.6E-18 T 28-03-2018 ALX04_RS12705 90eee62a7a908d538673463e0e469406 547 SMART SM00642 10 413 9.7E-130 T 28-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 ALX04_RS02740 c1c79df8984c6435152420799cf6dc64 272 Gene3D G3DSA:3.10.290.10 1 63 4.6E-15 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 ALX04_RS02740 c1c79df8984c6435152420799cf6dc64 272 PIRSF PIRSF005578 1 265 3.1E-99 T 28-03-2018 IPR004538 Haemolysin A /rRNA methyltransferase TlyA GO:0003723 ALX04_RS02740 c1c79df8984c6435152420799cf6dc64 272 TIGRFAM TIGR00478 tly: TlyA family rRNA methyltransferase/putative hemolysin 5 238 1.3E-84 T 28-03-2018 IPR004538 Haemolysin A /rRNA methyltransferase TlyA GO:0003723 ALX04_RS02740 c1c79df8984c6435152420799cf6dc64 272 Gene3D G3DSA:3.40.50.150 64 272 3.5E-57 T 28-03-2018 ALX04_RS02740 c1c79df8984c6435152420799cf6dc64 272 Pfam PF01479 S4 domain 4 46 9.7E-6 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 ALX04_RS02740 c1c79df8984c6435152420799cf6dc64 272 SUPERFAMILY SSF53335 54 244 2.16E-20 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase ALX04_RS02740 c1c79df8984c6435152420799cf6dc64 272 SMART SM00363 4 70 2.4E-4 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 ALX04_RS02740 c1c79df8984c6435152420799cf6dc64 272 Pfam PF01728 FtsJ-like methyltransferase 61 244 1.9E-17 T 28-03-2018 IPR002877 Ribosomal RNA methyltransferase FtsJ domain GO:0008168|GO:0032259 ALX04_RS02740 c1c79df8984c6435152420799cf6dc64 272 SUPERFAMILY SSF55174 2 70 2.65E-10 T 28-03-2018 ALX04_RS12430 e6ac55e7d4cb6ee3ff7be1b3dad0ecd0 147 Gene3D G3DSA:3.40.630.30 1 147 5.9E-16 T 28-03-2018 ALX04_RS12430 e6ac55e7d4cb6ee3ff7be1b3dad0ecd0 147 Pfam PF13673 Acetyltransferase (GNAT) domain 47 135 2.5E-12 T 28-03-2018 IPR000182 GNAT domain GO:0008080 ALX04_RS12430 e6ac55e7d4cb6ee3ff7be1b3dad0ecd0 147 SUPERFAMILY SSF55729 9 143 6.03E-16 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase ALX04_RS00370 a91a39e6f9b9b7c54980b2ab1d04130d 698 Hamap MF_00054_B Elongation factor G [fusA]. 8 692 109.453 T 28-03-2018 IPR004540 Translation elongation factor EFG/EF2 GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 ALX04_RS00370 a91a39e6f9b9b7c54980b2ab1d04130d 698 SUPERFAMILY SSF54211 480 600 3.79E-44 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold ALX04_RS00370 a91a39e6f9b9b7c54980b2ab1d04130d 698 Pfam PF00009 Elongation factor Tu GTP binding domain 11 283 6.0E-72 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 ALX04_RS00370 a91a39e6f9b9b7c54980b2ab1d04130d 698 TIGRFAM TIGR00484 EF-G: translation elongation factor G 4 692 0.0 T 28-03-2018 IPR004540 Translation elongation factor EFG/EF2 GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 ALX04_RS00370 a91a39e6f9b9b7c54980b2ab1d04130d 698 Pfam PF03764 Elongation factor G, domain IV 480 598 2.1E-47 T 28-03-2018 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 ALX04_RS00370 a91a39e6f9b9b7c54980b2ab1d04130d 698 Gene3D G3DSA:3.30.70.240 615 692 1.3E-33 T 28-03-2018 ALX04_RS00370 a91a39e6f9b9b7c54980b2ab1d04130d 698 SUPERFAMILY SSF50447 266 405 5.18E-34 T 28-03-2018 IPR009000 Translation protein, beta-barrel domain ALX04_RS00370 a91a39e6f9b9b7c54980b2ab1d04130d 698 SMART SM00889 481 599 1.5E-71 T 28-03-2018 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 ALX04_RS00370 a91a39e6f9b9b7c54980b2ab1d04130d 698 SUPERFAMILY SSF52540 8 283 1.91E-108 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase ALX04_RS00370 a91a39e6f9b9b7c54980b2ab1d04130d 698 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 11 182 2.5E-46 T 28-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 ALX04_RS00370 a91a39e6f9b9b7c54980b2ab1d04130d 698 SUPERFAMILY SSF54980 604 690 2.01E-30 T 28-03-2018 IPR035647 EF-G domain III/V-like ALX04_RS00370 a91a39e6f9b9b7c54980b2ab1d04130d 698 Pfam PF14492 Elongation Factor G, domain II 405 478 1.1E-33 T 28-03-2018 ALX04_RS00370 a91a39e6f9b9b7c54980b2ab1d04130d 698 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 53 68 - T 28-03-2018 IPR031157 Tr-type G domain, conserved site ALX04_RS00370 a91a39e6f9b9b7c54980b2ab1d04130d 698 Gene3D G3DSA:3.30.70.870 401 493 5.8E-36 T 28-03-2018 ALX04_RS00370 a91a39e6f9b9b7c54980b2ab1d04130d 698 SUPERFAMILY SSF54980 403 481 8.27E-25 T 28-03-2018 IPR035647 EF-G domain III/V-like ALX04_RS00370 a91a39e6f9b9b7c54980b2ab1d04130d 698 PRINTS PR00315 GTP-binding elongation factor signature 60 68 4.1E-17 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 ALX04_RS00370 a91a39e6f9b9b7c54980b2ab1d04130d 698 PRINTS PR00315 GTP-binding elongation factor signature 14 27 4.1E-17 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 ALX04_RS00370 a91a39e6f9b9b7c54980b2ab1d04130d 698 PRINTS PR00315 GTP-binding elongation factor signature 80 90 4.1E-17 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 ALX04_RS00370 a91a39e6f9b9b7c54980b2ab1d04130d 698 PRINTS PR00315 GTP-binding elongation factor signature 96 107 4.1E-17 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 ALX04_RS00370 a91a39e6f9b9b7c54980b2ab1d04130d 698 PRINTS PR00315 GTP-binding elongation factor signature 132 141 4.1E-17 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 ALX04_RS00370 a91a39e6f9b9b7c54980b2ab1d04130d 698 Gene3D G3DSA:3.40.50.300 4 288 4.2E-64 T 28-03-2018 ALX04_RS00370 a91a39e6f9b9b7c54980b2ab1d04130d 698 Gene3D G3DSA:3.30.230.10 494 614 3.1E-46 T 28-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup ALX04_RS00370 a91a39e6f9b9b7c54980b2ab1d04130d 698 SMART SM00838 601 688 1.5E-57 T 28-03-2018 IPR000640 Elongation factor EFG, domain V-like ALX04_RS00370 a91a39e6f9b9b7c54980b2ab1d04130d 698 Gene3D G3DSA:2.40.30.10 289 400 5.7E-28 T 28-03-2018 ALX04_RS00370 a91a39e6f9b9b7c54980b2ab1d04130d 698 Pfam PF00679 Elongation factor G C-terminus 601 687 6.5E-32 T 28-03-2018 IPR000640 Elongation factor EFG, domain V-like ALX04_RS00370 a91a39e6f9b9b7c54980b2ab1d04130d 698 Pfam PF03144 Elongation factor Tu domain 2 325 392 2.1E-13 T 28-03-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 ALX04_RS13115 e734effc0c8aa2b0dc3d83c928a274e5 187 Gene3D G3DSA:3.40.390.10 23 186 5.2E-21 T 28-03-2018 IPR024079 Metallopeptidase, catalytic domain GO:0008237 ALX04_RS13115 e734effc0c8aa2b0dc3d83c928a274e5 187 PRINTS PR00138 Matrixin signature 59 74 2.6E-5 T 28-03-2018 IPR021190 Peptidase M10A GO:0004222|GO:0006508|GO:0008270|GO:0031012 ALX04_RS13115 e734effc0c8aa2b0dc3d83c928a274e5 187 PRINTS PR00138 Matrixin signature 138 163 2.6E-5 T 28-03-2018 IPR021190 Peptidase M10A GO:0004222|GO:0006508|GO:0008270|GO:0031012 ALX04_RS13115 e734effc0c8aa2b0dc3d83c928a274e5 187 SUPERFAMILY SSF55486 33 183 1.3E-23 T 28-03-2018 ALX04_RS13115 e734effc0c8aa2b0dc3d83c928a274e5 187 Pfam PF00413 Matrixin 40 161 9.8E-8 T 28-03-2018 IPR001818 Peptidase M10, metallopeptidase GO:0004222|GO:0006508|GO:0008270|GO:0031012 ALX04_RS13115 e734effc0c8aa2b0dc3d83c928a274e5 187 SMART SM00235 36 182 3.2E-5 T 28-03-2018 IPR006026 Peptidase, metallopeptidase GO:0006508|GO:0008237|GO:0008270 ALX04_RS08115 07601fd0a90d56c7cfa6c77fd810e060 434 Pfam PF07690 Major Facilitator Superfamily 26 389 2.6E-18 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 ALX04_RS08115 07601fd0a90d56c7cfa6c77fd810e060 434 SUPERFAMILY SSF103473 21 423 3.14E-28 T 28-03-2018 IPR020846 Major facilitator superfamily domain ALX04_RS08115 07601fd0a90d56c7cfa6c77fd810e060 434 Gene3D G3DSA:1.20.1250.20 17 209 5.2E-12 T 28-03-2018 ALX04_RS08115 07601fd0a90d56c7cfa6c77fd810e060 434 Gene3D G3DSA:1.20.1250.20 226 427 3.0E-9 T 28-03-2018 ALX04_RS05160 36c313c16113f57f8d88581e42417ed0 252 Gene3D G3DSA:3.30.1890.10 37 153 5.6E-5 T 28-03-2018 ALX04_RS05160 36c313c16113f57f8d88581e42417ed0 252 Pfam PF02706 Chain length determinant protein 7 90 5.7E-8 T 28-03-2018 IPR003856 Polysaccharide chain length determinant N-terminal domain GO:0009103|GO:0016020 ALX04_RS05160 36c313c16113f57f8d88581e42417ed0 252 Pfam PF13807 G-rich domain on putative tyrosine kinase 146 196 7.3E-10 T 28-03-2018 IPR032807 Tyrosine kinase, G-rich domain ALX04_RS05570 03c8fcda8570e2396e00e480550eb0ee 39 Pfam PF13253 Protein of unknown function (DUF4044) 2 32 2.1E-15 T 28-03-2018 IPR025270 Protein of unknown function DUF4044 ALX04_RS13055 b82f91b95feec2e75dea87e0883073e3 323 Pfam PF03099 Biotin/lipoate A/B protein ligase family 87 214 9.2E-11 T 28-03-2018 IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain GO:0006464 ALX04_RS13055 b82f91b95feec2e75dea87e0883073e3 323 Gene3D G3DSA:1.10.10.10 2 56 1.3E-9 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS13055 b82f91b95feec2e75dea87e0883073e3 323 SUPERFAMILY SSF46785 7 60 1.54E-9 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS13055 b82f91b95feec2e75dea87e0883073e3 323 Hamap MF_00978 Bifunctional ligase/repressor BirA [birA]. 6 319 31.484 T 28-03-2018 IPR030855 Bifunctional ligase/repressor BirA GO:0004077|GO:0006355 KEGG: 00780+6.3.4.15 ALX04_RS13055 b82f91b95feec2e75dea87e0883073e3 323 TIGRFAM TIGR00121 birA_ligase: biotin--[acetyl-CoA-carboxylase] ligase 84 317 3.2E-37 T 28-03-2018 IPR004408 Biotin--acetyl-CoA-carboxylase ligase GO:0004077|GO:0006464 KEGG: 00780+6.3.4.15|Reactome: R-HSA-196780 ALX04_RS13055 b82f91b95feec2e75dea87e0883073e3 323 Pfam PF08279 HTH domain 4 57 1.1E-13 T 28-03-2018 IPR013196 Helix-turn-helix, type 11 ALX04_RS13055 b82f91b95feec2e75dea87e0883073e3 323 SUPERFAMILY SSF50037 274 318 3.3E-7 T 28-03-2018 IPR008988 Transcriptional repressor, C-terminal ALX04_RS13055 b82f91b95feec2e75dea87e0883073e3 323 SUPERFAMILY SSF55681 74 264 7.12E-41 T 28-03-2018 ALX04_RS13055 b82f91b95feec2e75dea87e0883073e3 323 Gene3D G3DSA:2.30.30.100 273 319 1.2E-12 T 28-03-2018 ALX04_RS13055 b82f91b95feec2e75dea87e0883073e3 323 Pfam PF02237 Biotin protein ligase C terminal domain 273 317 7.0E-10 T 28-03-2018 IPR003142 Biotin protein ligase, C-terminal GO:0006464 KEGG: 00780+6.3.4.15|Reactome: R-HSA-196780 ALX04_RS13055 b82f91b95feec2e75dea87e0883073e3 323 Gene3D G3DSA:3.30.930.10 57 272 3.1E-44 T 28-03-2018 ALX04_RS02800 768a2fd90c7d41bb4aa1af220a735809 317 SUPERFAMILY SSF50486 205 308 3.34E-24 T 28-03-2018 IPR011034 Formyl transferase, C-terminal-like GO:0003824 ALX04_RS02800 768a2fd90c7d41bb4aa1af220a735809 317 Gene3D G3DSA:3.10.25.10 207 314 2.8E-24 T 28-03-2018 IPR005793 Formyl transferase, C-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 ALX04_RS02800 768a2fd90c7d41bb4aa1af220a735809 317 Hamap MF_00182 Methionyl-tRNA formyltransferase [fmt]. 2 307 33.741 T 28-03-2018 IPR005794 Methionyl-tRNA formyltransferase GO:0004479|GO:0071951 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9|Reactome: R-HSA-5368286 ALX04_RS02800 768a2fd90c7d41bb4aa1af220a735809 317 Pfam PF00551 Formyl transferase 4 180 4.5E-37 T 28-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 ALX04_RS02800 768a2fd90c7d41bb4aa1af220a735809 317 ProSitePatterns PS00373 Phosphoribosylglycinamide formyltransferase active site. 133 156 - T 28-03-2018 IPR001555 Phosphoribosylglycinamide formyltransferase, active site KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 ALX04_RS02800 768a2fd90c7d41bb4aa1af220a735809 317 Gene3D G3DSA:3.40.50.170 1 206 7.8E-66 T 28-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 ALX04_RS02800 768a2fd90c7d41bb4aa1af220a735809 317 SUPERFAMILY SSF53328 4 203 1.57E-64 T 28-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 ALX04_RS02800 768a2fd90c7d41bb4aa1af220a735809 317 TIGRFAM TIGR00460 fmt: methionyl-tRNA formyltransferase 3 309 1.9E-94 T 28-03-2018 IPR005794 Methionyl-tRNA formyltransferase GO:0004479|GO:0071951 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9|Reactome: R-HSA-5368286 ALX04_RS02800 768a2fd90c7d41bb4aa1af220a735809 317 Pfam PF02911 Formyl transferase, C-terminal domain 204 304 1.6E-24 T 28-03-2018 IPR005793 Formyl transferase, C-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 ALX04_RS12035 bbe866bceae18c0eb778b71974bd0edc 263 PIRSF PIRSF000513 1 263 9.7E-97 T 28-03-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 ALX04_RS12035 bbe866bceae18c0eb778b71974bd0edc 263 Gene3D G3DSA:3.40.1190.20 2 263 3.8E-54 T 28-03-2018 IPR029056 Ribokinase-like ALX04_RS12035 bbe866bceae18c0eb778b71974bd0edc 263 Pfam PF02110 Hydroxyethylthiazole kinase family 6 252 7.8E-74 T 28-03-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 ALX04_RS12035 bbe866bceae18c0eb778b71974bd0edc 263 PRINTS PR01099 Hydroxyethylthiazole kinase family signature 84 101 9.9E-34 T 28-03-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 ALX04_RS12035 bbe866bceae18c0eb778b71974bd0edc 263 PRINTS PR01099 Hydroxyethylthiazole kinase family signature 14 21 9.9E-34 T 28-03-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 ALX04_RS12035 bbe866bceae18c0eb778b71974bd0edc 263 PRINTS PR01099 Hydroxyethylthiazole kinase family signature 159 176 9.9E-34 T 28-03-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 ALX04_RS12035 bbe866bceae18c0eb778b71974bd0edc 263 PRINTS PR01099 Hydroxyethylthiazole kinase family signature 27 48 9.9E-34 T 28-03-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 ALX04_RS12035 bbe866bceae18c0eb778b71974bd0edc 263 PRINTS PR01099 Hydroxyethylthiazole kinase family signature 115 129 9.9E-34 T 28-03-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 ALX04_RS12035 bbe866bceae18c0eb778b71974bd0edc 263 PRINTS PR01099 Hydroxyethylthiazole kinase family signature 58 66 9.9E-34 T 28-03-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 ALX04_RS12035 bbe866bceae18c0eb778b71974bd0edc 263 SUPERFAMILY SSF53613 4 256 2.46E-58 T 28-03-2018 IPR029056 Ribokinase-like ALX04_RS12035 bbe866bceae18c0eb778b71974bd0edc 263 Hamap MF_00228 Hydroxyethylthiazole kinase [thiM]. 8 257 30.019 T 28-03-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 ALX04_RS05400 e7b7531ba952ee1d9867c796feb7601a 221 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 4 207 5.5E-57 T 28-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 ALX04_RS05400 e7b7531ba952ee1d9867c796feb7601a 221 Gene3D G3DSA:3.40.50.1240 2 220 3.3E-52 T 28-03-2018 IPR029033 Histidine phosphatase superfamily ALX04_RS05400 e7b7531ba952ee1d9867c796feb7601a 221 SMART SM00855 3 165 2.1E-22 T 28-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 ALX04_RS05400 e7b7531ba952ee1d9867c796feb7601a 221 SUPERFAMILY SSF53254 2 213 7.4E-58 T 28-03-2018 IPR029033 Histidine phosphatase superfamily ALX04_RS05400 e7b7531ba952ee1d9867c796feb7601a 221 PIRSF PIRSF000709 2 179 1.5E-18 T 28-03-2018 ALX04_RS05430 dc67c82c5177646289ab2cef6e2cf0da 379 TIGRFAM TIGR00420 trmU: tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase 13 366 1.3E-136 T 28-03-2018 IPR004506 tRNA-specific 2-thiouridylase GO:0008033|GO:0016740 Reactome: R-HSA-6787450 ALX04_RS05430 dc67c82c5177646289ab2cef6e2cf0da 379 Pfam PF03054 tRNA methyl transferase 13 366 3.7E-145 T 28-03-2018 ALX04_RS05430 dc67c82c5177646289ab2cef6e2cf0da 379 SUPERFAMILY SSF52402 10 250 2.65E-59 T 28-03-2018 ALX04_RS05430 dc67c82c5177646289ab2cef6e2cf0da 379 Gene3D G3DSA:2.40.30.10 287 379 1.4E-27 T 28-03-2018 ALX04_RS05430 dc67c82c5177646289ab2cef6e2cf0da 379 Gene3D G3DSA:3.40.50.620 3 218 2.7E-69 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold ALX04_RS05430 dc67c82c5177646289ab2cef6e2cf0da 379 Hamap MF_00144 tRNA-specific 2-thiouridylase MnmA [mnmA]. 12 367 41.161 T 28-03-2018 IPR004506 tRNA-specific 2-thiouridylase GO:0008033|GO:0016740 Reactome: R-HSA-6787450 ALX04_RS05430 dc67c82c5177646289ab2cef6e2cf0da 379 Gene3D G3DSA:2.30.30.280 219 285 1.9E-26 T 28-03-2018 IPR023382 Adenine nucleotide alpha hydrolase-like domains GO:0016783 Reactome: R-HSA-6787450 ALX04_RS11550 37d078c2f4c09e04f9de68467983998f 322 Pfam PF14804 Jag N-terminus 4 53 6.9E-17 T 28-03-2018 IPR032782 Jag, N-terminal ALX04_RS11550 37d078c2f4c09e04f9de68467983998f 322 SUPERFAMILY SSF82708 276 318 2.75E-9 T 28-03-2018 IPR001374 R3H domain GO:0003676 ALX04_RS11550 37d078c2f4c09e04f9de68467983998f 322 SMART SM01245 3 54 3.3E-19 T 28-03-2018 IPR032782 Jag, N-terminal ALX04_RS11550 37d078c2f4c09e04f9de68467983998f 322 Gene3D G3DSA:3.30.30.80 1 51 2.2E-16 T 28-03-2018 ALX04_RS11550 37d078c2f4c09e04f9de68467983998f 322 Gene3D G3DSA:3.30.1370.50 257 322 1.5E-16 T 28-03-2018 IPR001374 R3H domain GO:0003676 ALX04_RS11550 37d078c2f4c09e04f9de68467983998f 322 Gene3D G3DSA:3.30.300.20 174 256 5.8E-15 T 28-03-2018 IPR015946 K homology domain-like, alpha/beta ALX04_RS11550 37d078c2f4c09e04f9de68467983998f 322 Pfam PF01424 R3H domain 261 318 5.7E-13 T 28-03-2018 IPR001374 R3H domain GO:0003676 ALX04_RS11550 37d078c2f4c09e04f9de68467983998f 322 SMART SM00393 242 321 4.6E-15 T 28-03-2018 IPR001374 R3H domain GO:0003676 ALX04_RS11550 37d078c2f4c09e04f9de68467983998f 322 Pfam PF13083 KH domain 182 247 4.0E-11 T 28-03-2018 ALX04_RS04085 8c91eb79aacb137c4cf1c40fc87603cf 429 PRINTS PR00148 Enolase signature 39 53 9.0E-40 T 28-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 ALX04_RS04085 8c91eb79aacb137c4cf1c40fc87603cf 429 PRINTS PR00148 Enolase signature 335 349 9.0E-40 T 28-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 ALX04_RS04085 8c91eb79aacb137c4cf1c40fc87603cf 429 PRINTS PR00148 Enolase signature 161 174 9.0E-40 T 28-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 ALX04_RS04085 8c91eb79aacb137c4cf1c40fc87603cf 429 PRINTS PR00148 Enolase signature 108 124 9.0E-40 T 28-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 ALX04_RS04085 8c91eb79aacb137c4cf1c40fc87603cf 429 PRINTS PR00148 Enolase signature 312 323 9.0E-40 T 28-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 ALX04_RS04085 8c91eb79aacb137c4cf1c40fc87603cf 429 PRINTS PR00148 Enolase signature 364 381 9.0E-40 T 28-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 ALX04_RS04085 8c91eb79aacb137c4cf1c40fc87603cf 429 PIRSF PIRSF001400 2 422 7.0E-180 T 28-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 ALX04_RS04085 8c91eb79aacb137c4cf1c40fc87603cf 429 SUPERFAMILY SSF51604 140 417 4.85E-106 T 28-03-2018 IPR029065 Enolase C-terminal domain-like ALX04_RS04085 8c91eb79aacb137c4cf1c40fc87603cf 429 ProSitePatterns PS00164 Enolase signature. 335 348 - T 28-03-2018 IPR020809 Enolase, conserved site KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|Reactome: R-HSA-70171|Reactome: R-HSA-70263 ALX04_RS04085 8c91eb79aacb137c4cf1c40fc87603cf 429 Hamap MF_00318 Enolase [eno]. 4 412 40.828 T 28-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 ALX04_RS04085 8c91eb79aacb137c4cf1c40fc87603cf 429 Pfam PF00113 Enolase, C-terminal TIM barrel domain 142 415 3.0E-104 T 28-03-2018 IPR020810 Enolase, C-terminal TIM barrel domain KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 ALX04_RS04085 8c91eb79aacb137c4cf1c40fc87603cf 429 Gene3D G3DSA:3.20.20.120 129 423 1.4E-85 T 28-03-2018 IPR029065 Enolase C-terminal domain-like ALX04_RS04085 8c91eb79aacb137c4cf1c40fc87603cf 429 Gene3D G3DSA:3.30.390.10 5 128 3.9E-50 T 28-03-2018 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 ALX04_RS04085 8c91eb79aacb137c4cf1c40fc87603cf 429 TIGRFAM TIGR01060 eno: phosphopyruvate hydratase 6 416 1.3E-173 T 28-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 ALX04_RS04085 8c91eb79aacb137c4cf1c40fc87603cf 429 SMART SM01193 6 135 1.7E-87 T 28-03-2018 IPR020811 Enolase, N-terminal KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 ALX04_RS04085 8c91eb79aacb137c4cf1c40fc87603cf 429 Pfam PF03952 Enolase, N-terminal domain 6 135 1.3E-56 T 28-03-2018 IPR020811 Enolase, N-terminal KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 ALX04_RS04085 8c91eb79aacb137c4cf1c40fc87603cf 429 SMART SM01192 139 422 2.5E-164 T 28-03-2018 IPR020810 Enolase, C-terminal TIM barrel domain KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 ALX04_RS04085 8c91eb79aacb137c4cf1c40fc87603cf 429 SUPERFAMILY SSF54826 5 137 1.08E-52 T 28-03-2018 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 ALX04_RS04695 ac727a6b24035ab9ee950871169c6886 210 Hamap MF_00015 LexA repressor [lexA]. 4 207 31.259 T 28-03-2018 IPR006200 Transcription regulator LexA GO:0004252|GO:0009432|GO:0045892 ALX04_RS04695 ac727a6b24035ab9ee950871169c6886 210 Gene3D G3DSA:2.10.109.10 90 207 8.9E-24 T 28-03-2018 ALX04_RS04695 ac727a6b24035ab9ee950871169c6886 210 Pfam PF01726 LexA DNA binding domain 8 66 1.8E-22 T 28-03-2018 IPR006199 LexA repressor, DNA-binding domain GO:0004252|GO:0006508 ALX04_RS04695 ac727a6b24035ab9ee950871169c6886 210 Gene3D G3DSA:1.10.10.10 1 71 5.4E-14 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS04695 ac727a6b24035ab9ee950871169c6886 210 Pfam PF00717 Peptidase S24-like 125 193 1.0E-15 T 28-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C ALX04_RS04695 ac727a6b24035ab9ee950871169c6886 210 SUPERFAMILY SSF46785 7 70 4.36E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS04695 ac727a6b24035ab9ee950871169c6886 210 TIGRFAM TIGR00498 lexA: repressor LexA 7 207 3.0E-64 T 28-03-2018 IPR006200 Transcription regulator LexA GO:0004252|GO:0009432|GO:0045892 ALX04_RS04695 ac727a6b24035ab9ee950871169c6886 210 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 133 144 1.1E-6 T 28-03-2018 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 ALX04_RS04695 ac727a6b24035ab9ee950871169c6886 210 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 162 174 1.1E-6 T 28-03-2018 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 ALX04_RS04695 ac727a6b24035ab9ee950871169c6886 210 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 122 132 1.1E-6 T 28-03-2018 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 ALX04_RS04695 ac727a6b24035ab9ee950871169c6886 210 SUPERFAMILY SSF51306 85 205 2.27E-32 T 28-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C ALX04_RS11330 1dc26fb928159066fc7154884c1ab767 401 SUPERFAMILY SSF55424 320 392 7.05E-19 T 28-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 ALX04_RS11330 1dc26fb928159066fc7154884c1ab767 401 SUPERFAMILY SSF51905 195 336 5.99E-39 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ALX04_RS11330 1dc26fb928159066fc7154884c1ab767 401 SUPERFAMILY SSF51905 7 166 5.99E-39 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ALX04_RS11330 1dc26fb928159066fc7154884c1ab767 401 Gene3D G3DSA:3.30.390.30 324 398 9.7E-16 T 28-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 ALX04_RS11330 1dc26fb928159066fc7154884c1ab767 401 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 149 167 2.4E-20 T 28-03-2018 ALX04_RS11330 1dc26fb928159066fc7154884c1ab767 401 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 260 282 2.4E-20 T 28-03-2018 ALX04_RS11330 1dc26fb928159066fc7154884c1ab767 401 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 106 124 2.4E-20 T 28-03-2018 ALX04_RS11330 1dc26fb928159066fc7154884c1ab767 401 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 234 250 2.4E-20 T 28-03-2018 ALX04_RS11330 1dc26fb928159066fc7154884c1ab767 401 Gene3D G3DSA:3.50.50.60 109 239 3.4E-29 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ALX04_RS11330 1dc26fb928159066fc7154884c1ab767 401 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 149 174 9.3E-16 T 28-03-2018 ALX04_RS11330 1dc26fb928159066fc7154884c1ab767 401 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 109 118 9.3E-16 T 28-03-2018 ALX04_RS11330 1dc26fb928159066fc7154884c1ab767 401 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 275 282 9.3E-16 T 28-03-2018 ALX04_RS11330 1dc26fb928159066fc7154884c1ab767 401 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 235 249 9.3E-16 T 28-03-2018 ALX04_RS11330 1dc26fb928159066fc7154884c1ab767 401 Gene3D G3DSA:3.50.50.60 249 323 5.5E-8 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ALX04_RS11330 1dc26fb928159066fc7154884c1ab767 401 Gene3D G3DSA:3.50.50.60 2 108 2.2E-9 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ALX04_RS11330 1dc26fb928159066fc7154884c1ab767 401 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 10 302 6.5E-51 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ALX04_RS00935 91160e7e69790dd7c93c27e89056cca7 66 Pfam PF00313 'Cold-shock' DNA-binding domain 3 64 2.2E-30 T 28-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 ALX04_RS00935 91160e7e69790dd7c93c27e89056cca7 66 ProSitePatterns PS00352 'Cold-shock' domain signature. 15 33 - T 28-03-2018 IPR019844 Cold-shock conserved site ALX04_RS00935 91160e7e69790dd7c93c27e89056cca7 66 PIRSF PIRSF002599 1 66 1.5E-23 T 28-03-2018 IPR012156 Cold shock, CspA GO:0003676 ALX04_RS00935 91160e7e69790dd7c93c27e89056cca7 66 SUPERFAMILY SSF50249 1 65 1.89E-24 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold ALX04_RS00935 91160e7e69790dd7c93c27e89056cca7 66 Gene3D G3DSA:2.40.50.140 1 65 1.7E-26 T 28-03-2018 ALX04_RS00935 91160e7e69790dd7c93c27e89056cca7 66 PRINTS PR00050 Cold shock protein signature 4 19 1.1E-16 T 28-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 ALX04_RS00935 91160e7e69790dd7c93c27e89056cca7 66 PRINTS PR00050 Cold shock protein signature 24 33 1.1E-16 T 28-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 ALX04_RS00935 91160e7e69790dd7c93c27e89056cca7 66 PRINTS PR00050 Cold shock protein signature 39 57 1.1E-16 T 28-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 ALX04_RS00935 91160e7e69790dd7c93c27e89056cca7 66 SMART SM00357 3 66 4.9E-29 T 28-03-2018 IPR011129 Cold shock domain GO:0003676 ALX04_RS06110 67d1ee22b8da00db7c299c789ff0a66e 420 Gene3D G3DSA:3.90.950.20 252 417 6.6E-54 T 28-03-2018 ALX04_RS06110 67d1ee22b8da00db7c299c789ff0a66e 420 TIGRFAM TIGR00199 PncC_domain: amidohydrolase, PncC family 266 410 1.7E-40 T 28-03-2018 IPR008136 CinA, C-terminal ALX04_RS06110 67d1ee22b8da00db7c299c789ff0a66e 420 TIGRFAM TIGR00200 cinA_nterm: competence/damage-inducible protein CinA N-terminal domain 1 413 1.1E-125 T 28-03-2018 IPR008135 Competence-induced protein CinA ALX04_RS06110 67d1ee22b8da00db7c299c789ff0a66e 420 Pfam PF00994 Probable molybdopterin binding domain 4 169 6.8E-31 T 28-03-2018 IPR001453 MoaB/Mog domain ALX04_RS06110 67d1ee22b8da00db7c299c789ff0a66e 420 SUPERFAMILY SSF53218 1 206 2.36E-38 T 28-03-2018 IPR001453 MoaB/Mog domain ALX04_RS06110 67d1ee22b8da00db7c299c789ff0a66e 420 Pfam PF02464 Competence-damaged protein 260 412 4.6E-52 T 28-03-2018 IPR008136 CinA, C-terminal ALX04_RS06110 67d1ee22b8da00db7c299c789ff0a66e 420 PIRSF PIRSF006728 1 418 9.2E-159 T 28-03-2018 IPR008135 Competence-induced protein CinA ALX04_RS06110 67d1ee22b8da00db7c299c789ff0a66e 420 Hamap MF_00226_B Putative competence-damage inducible protein [cinA]. 1 420 157.185 T 28-03-2018 IPR008135 Competence-induced protein CinA ALX04_RS06110 67d1ee22b8da00db7c299c789ff0a66e 420 TIGRFAM TIGR00177 molyb_syn: molybdenum cofactor synthesis domain 2 167 1.4E-26 T 28-03-2018 IPR001453 MoaB/Mog domain ALX04_RS06110 67d1ee22b8da00db7c299c789ff0a66e 420 Gene3D G3DSA:3.40.980.10 1 172 1.4E-38 T 28-03-2018 IPR001453 MoaB/Mog domain ALX04_RS06110 67d1ee22b8da00db7c299c789ff0a66e 420 SMART SM00852 4 172 1.4E-38 T 28-03-2018 IPR001453 MoaB/Mog domain ALX04_RS06110 67d1ee22b8da00db7c299c789ff0a66e 420 SUPERFAMILY SSF142433 253 412 1.96E-48 T 28-03-2018 IPR008136 CinA, C-terminal ALX04_RS12415 683151d93df9ee55ec614fb83df3c238 280 Pfam PF01381 Helix-turn-helix 8 58 3.2E-9 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 ALX04_RS12415 683151d93df9ee55ec614fb83df3c238 280 SMART SM00530 5 59 6.5E-8 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 ALX04_RS12415 683151d93df9ee55ec614fb83df3c238 280 Gene3D G3DSA:1.25.40.10 68 275 2.8E-8 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 ALX04_RS12415 683151d93df9ee55ec614fb83df3c238 280 Gene3D G3DSA:1.10.260.40 4 67 1.7E-9 T 28-03-2018 ALX04_RS12415 683151d93df9ee55ec614fb83df3c238 280 SUPERFAMILY SSF47413 8 60 7.32E-9 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 ALX04_RS03120 c486baa99f1f9f6c991d4de6ed5cf34f 54 Pfam PF00589 Phage integrase family 2 53 1.8E-9 T 28-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 ALX04_RS03120 c486baa99f1f9f6c991d4de6ed5cf34f 54 SUPERFAMILY SSF56349 3 53 3.24E-12 T 28-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 ALX04_RS03120 c486baa99f1f9f6c991d4de6ed5cf34f 54 Gene3D G3DSA:1.10.443.10 1 54 3.5E-12 T 28-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 ALX04_RS07270 b426f943193c8f607b4c96a20a40a33e 356 TIGRFAM TIGR01141 hisC: histidinol-phosphate transaminase 3 352 2.4E-93 T 28-03-2018 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9 ALX04_RS07270 b426f943193c8f607b4c96a20a40a33e 356 SUPERFAMILY SSF53383 22 352 1.88E-80 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase ALX04_RS07270 b426f943193c8f607b4c96a20a40a33e 356 Hamap MF_01023 Histidinol-phosphate aminotransferase [hisC]. 1 355 56.151 T 28-03-2018 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9 ALX04_RS07270 b426f943193c8f607b4c96a20a40a33e 356 Pfam PF00155 Aminotransferase class I and II 28 352 3.8E-57 T 28-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 ALX04_RS07270 b426f943193c8f607b4c96a20a40a33e 356 Gene3D G3DSA:3.90.1150.10 280 354 4.2E-14 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 ALX04_RS07270 b426f943193c8f607b4c96a20a40a33e 356 Gene3D G3DSA:3.40.640.10 42 279 1.7E-41 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 ALX04_RS14680 164a86d5120c945d62696a0272bbc2dc 951 SUPERFAMILY SSF52540 613 912 2.66E-51 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase ALX04_RS14680 164a86d5120c945d62696a0272bbc2dc 951 SUPERFAMILY SSF52540 430 569 3.63E-47 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase ALX04_RS14680 164a86d5120c945d62696a0272bbc2dc 951 SUPERFAMILY SSF52540 11 206 3.63E-47 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase ALX04_RS14680 164a86d5120c945d62696a0272bbc2dc 951 Gene3D G3DSA:3.40.50.300 37 117 2.2E-4 T 28-03-2018 ALX04_RS14680 164a86d5120c945d62696a0272bbc2dc 951 Hamap MF_00205 UvrABC system protein A [uvrA]. 3 938 22.689 T 28-03-2018 IPR004602 UvrABC system subunit A GO:0006289|GO:0009380|GO:0009381 ALX04_RS14680 164a86d5120c945d62696a0272bbc2dc 951 Gene3D G3DSA:1.10.8.280 284 404 8.3E-37 T 28-03-2018 ALX04_RS14680 164a86d5120c945d62696a0272bbc2dc 951 Pfam PF00005 ABC transporter 622 858 1.2E-9 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 ALX04_RS14680 164a86d5120c945d62696a0272bbc2dc 951 ProSitePatterns PS00211 ABC transporters family signature. 828 842 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 ALX04_RS14680 164a86d5120c945d62696a0272bbc2dc 951 Gene3D G3DSA:3.30.190.20 129 247 2.2E-41 T 28-03-2018 ALX04_RS14680 164a86d5120c945d62696a0272bbc2dc 951 Gene3D G3DSA:3.40.50.300 3 36 0.0067 T 28-03-2018 ALX04_RS14680 164a86d5120c945d62696a0272bbc2dc 951 Gene3D G3DSA:3.40.50.300 433 616 3.2E-22 T 28-03-2018 ALX04_RS14680 164a86d5120c945d62696a0272bbc2dc 951 SMART SM00382 631 906 3.2E-4 T 28-03-2018 IPR003593 AAA+ ATPase domain ALX04_RS14680 164a86d5120c945d62696a0272bbc2dc 951 SMART SM00382 25 564 22.0 T 28-03-2018 IPR003593 AAA+ ATPase domain ALX04_RS14680 164a86d5120c945d62696a0272bbc2dc 951 Gene3D G3DSA:3.40.50.300 617 950 1.2E-56 T 28-03-2018 ALX04_RS14680 164a86d5120c945d62696a0272bbc2dc 951 TIGRFAM TIGR00630 uvra: excinuclease ABC subunit A 5 923 0.0 T 28-03-2018 IPR004602 UvrABC system subunit A GO:0006289|GO:0009380|GO:0009381 ALX04_RS14680 164a86d5120c945d62696a0272bbc2dc 951 ProSitePatterns PS00211 ABC transporters family signature. 487 501 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 ALX04_RS07455 54d186804f01888c2ac4d629d9f2bef9 325 Gene3D G3DSA:3.40.50.720 1 143 1.5E-33 T 28-03-2018 ALX04_RS07455 54d186804f01888c2ac4d629d9f2bef9 325 Gene3D G3DSA:3.30.360.10 144 325 4.8E-21 T 28-03-2018 ALX04_RS07455 54d186804f01888c2ac4d629d9f2bef9 325 SUPERFAMILY SSF55347 131 292 6.05E-18 T 28-03-2018 ALX04_RS07455 54d186804f01888c2ac4d629d9f2bef9 325 SUPERFAMILY SSF51735 2 153 9.56E-39 T 28-03-2018 IPR016040 NAD(P)-binding domain ALX04_RS07455 54d186804f01888c2ac4d629d9f2bef9 325 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 1 119 8.7E-23 T 28-03-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 ALX04_RS03720 0590eac95849f3cf58f19a50a7bc6936 284 Pfam PF13495 Phage integrase, N-terminal SAM-like domain 10 94 6.2E-10 T 28-03-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 ALX04_RS03720 0590eac95849f3cf58f19a50a7bc6936 284 SUPERFAMILY SSF56349 7 143 1.65E-11 T 28-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 ALX04_RS03720 0590eac95849f3cf58f19a50a7bc6936 284 Gene3D G3DSA:1.10.150.130 5 115 2.9E-15 T 28-03-2018 IPR023109 Integrase/recombinase, N-terminal ALX04_RS01640 2b2f07df79c2fdc8faa5dbe5cbbcb733 198 Pfam PF06962 Putative rRNA methylase 59 196 1.0E-48 T 28-03-2018 IPR010719 Putative rRNA methylase ALX04_RS01640 2b2f07df79c2fdc8faa5dbe5cbbcb733 198 Gene3D G3DSA:3.40.50.150 10 198 1.4E-19 T 28-03-2018 ALX04_RS01640 2b2f07df79c2fdc8faa5dbe5cbbcb733 198 SUPERFAMILY SSF53335 18 197 5.52E-20 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase ALX04_RS03510 e3227f2bd96634540fc337e25465e7a5 149 TIGRFAM TIGR00077 lspA: signal peptidase II 3 142 1.2E-33 T 28-03-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 ALX04_RS03510 e3227f2bd96634540fc337e25465e7a5 149 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 123 139 2.7E-16 T 28-03-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 ALX04_RS03510 e3227f2bd96634540fc337e25465e7a5 149 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 46 54 2.7E-16 T 28-03-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 ALX04_RS03510 e3227f2bd96634540fc337e25465e7a5 149 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 89 104 2.7E-16 T 28-03-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 ALX04_RS03510 e3227f2bd96634540fc337e25465e7a5 149 Pfam PF01252 Signal peptidase (SPase) II 8 142 2.0E-35 T 28-03-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 ALX04_RS03510 e3227f2bd96634540fc337e25465e7a5 149 ProSitePatterns PS00855 Signal peptidases II signature. 92 104 - T 28-03-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 ALX04_RS03510 e3227f2bd96634540fc337e25465e7a5 149 Hamap MF_00161 Lipoprotein signal peptidase [lspA]. 1 148 15.977 T 28-03-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 ALX04_RS02240 9890ff918d0680e4f5a5eb8c66b913ea 997 Gene3D G3DSA:1.10.10.10 925 979 5.6E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS02240 9890ff918d0680e4f5a5eb8c66b913ea 997 Gene3D G3DSA:3.40.50.300 540 877 5.0E-49 T 28-03-2018 ALX04_RS02240 9890ff918d0680e4f5a5eb8c66b913ea 997 Pfam PF09397 Ftsk gamma domain 925 985 4.8E-24 T 28-03-2018 IPR018541 FtsK gamma domain ALX04_RS02240 9890ff918d0680e4f5a5eb8c66b913ea 997 Pfam PF01580 FtsK/SpoIIIE family 637 775 2.2E-45 T 28-03-2018 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 ALX04_RS02240 9890ff918d0680e4f5a5eb8c66b913ea 997 Pfam PF01580 FtsK/SpoIIIE family 779 829 7.8E-14 T 28-03-2018 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 ALX04_RS02240 9890ff918d0680e4f5a5eb8c66b913ea 997 SUPERFAMILY SSF52540 610 892 4.98E-45 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase ALX04_RS02240 9890ff918d0680e4f5a5eb8c66b913ea 997 SMART SM00843 923 988 5.9E-28 T 28-03-2018 IPR018541 FtsK gamma domain ALX04_RS02240 9890ff918d0680e4f5a5eb8c66b913ea 997 SMART SM00382 672 871 1.6E-4 T 28-03-2018 IPR003593 AAA+ ATPase domain ALX04_RS02240 9890ff918d0680e4f5a5eb8c66b913ea 997 SUPERFAMILY SSF46785 925 988 6.46E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS00965 d16275b086a8f0bd4ca347e3839b7605 288 SUPERFAMILY SSF53474 41 67 1.05E-10 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold ALX04_RS00965 d16275b086a8f0bd4ca347e3839b7605 288 SUPERFAMILY SSF53474 97 180 1.05E-10 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold ALX04_RS00965 d16275b086a8f0bd4ca347e3839b7605 288 Gene3D G3DSA:3.40.50.1820 39 288 4.1E-26 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold ALX04_RS00965 d16275b086a8f0bd4ca347e3839b7605 288 Pfam PF06028 Alpha/beta hydrolase of unknown function (DUF915) 36 270 1.9E-63 T 28-03-2018 IPR010315 Protein of unknown function DUF915, hydrolase-like ALX04_RS11090 e2710e6c81cfea4e0d3de0d1fbd287bc 294 Gene3D G3DSA:3.40.50.720 120 291 3.4E-34 T 28-03-2018 ALX04_RS11090 e2710e6c81cfea4e0d3de0d1fbd287bc 294 Gene3D G3DSA:3.40.50.10860 1 119 2.6E-41 T 28-03-2018 ALX04_RS11090 e2710e6c81cfea4e0d3de0d1fbd287bc 294 Hamap MF_00222 Shikimate dehydrogenase (NADP(+)) [aroE]. 9 289 30.838 T 28-03-2018 IPR022893 Shikimate dehydrogenase family GO:0004764|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163 ALX04_RS11090 e2710e6c81cfea4e0d3de0d1fbd287bc 294 TIGRFAM TIGR00507 aroE: shikimate dehydrogenase 11 286 7.9E-63 T 28-03-2018 IPR011342 Shikimate dehydrogenase GO:0004764|GO:0019632|GO:0050661|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163 ALX04_RS11090 e2710e6c81cfea4e0d3de0d1fbd287bc 294 SUPERFAMILY SSF51735 109 286 5.17E-37 T 28-03-2018 IPR016040 NAD(P)-binding domain ALX04_RS11090 e2710e6c81cfea4e0d3de0d1fbd287bc 294 Pfam PF08501 Shikimate dehydrogenase substrate binding domain 14 96 6.1E-27 T 28-03-2018 IPR013708 Shikimate dehydrogenase substrate binding, N-terminal GO:0004764|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163 ALX04_RS11090 e2710e6c81cfea4e0d3de0d1fbd287bc 294 SUPERFAMILY SSF53223 4 108 3.51E-33 T 28-03-2018 ALX04_RS04515 fbd5084e9b58ace49fbeeb321bf9cc9c 380 Gene3D G3DSA:1.10.287.110 1 118 1.5E-36 T 28-03-2018 IPR001623 DnaJ domain ALX04_RS04515 fbd5084e9b58ace49fbeeb321bf9cc9c 380 Gene3D G3DSA:2.60.260.20 265 374 2.5E-26 T 28-03-2018 ALX04_RS04515 fbd5084e9b58ace49fbeeb321bf9cc9c 380 TIGRFAM TIGR02349 DnaJ_bact: chaperone protein DnaJ 5 360 1.3E-135 T 28-03-2018 IPR012724 Chaperone DnaJ GO:0005524|GO:0006457|GO:0009408|GO:0051082 ALX04_RS04515 fbd5084e9b58ace49fbeeb321bf9cc9c 380 SUPERFAMILY SSF57938 140 220 7.85E-19 T 28-03-2018 IPR001305 Heat shock protein DnaJ, cysteine-rich domain GO:0031072|GO:0051082 ALX04_RS04515 fbd5084e9b58ace49fbeeb321bf9cc9c 380 SUPERFAMILY SSF49493 269 354 1.96E-21 T 28-03-2018 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 ALX04_RS04515 fbd5084e9b58ace49fbeeb321bf9cc9c 380 Pfam PF00684 DnaJ central domain 153 217 4.1E-13 T 28-03-2018 IPR001305 Heat shock protein DnaJ, cysteine-rich domain GO:0031072|GO:0051082 ALX04_RS04515 fbd5084e9b58ace49fbeeb321bf9cc9c 380 Pfam PF00226 DnaJ domain 5 66 2.8E-27 T 28-03-2018 IPR001623 DnaJ domain ALX04_RS04515 fbd5084e9b58ace49fbeeb321bf9cc9c 380 SUPERFAMILY SSF46565 2 105 6.15E-36 T 28-03-2018 IPR001623 DnaJ domain ALX04_RS04515 fbd5084e9b58ace49fbeeb321bf9cc9c 380 SMART SM00271 4 61 6.6E-30 T 28-03-2018 IPR001623 DnaJ domain ALX04_RS04515 fbd5084e9b58ace49fbeeb321bf9cc9c 380 SUPERFAMILY SSF49493 120 161 3.01E-16 T 28-03-2018 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 ALX04_RS04515 fbd5084e9b58ace49fbeeb321bf9cc9c 380 SUPERFAMILY SSF49493 224 266 3.01E-16 T 28-03-2018 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 ALX04_RS04515 fbd5084e9b58ace49fbeeb321bf9cc9c 380 Gene3D G3DSA:2.10.230.10 153 203 8.0E-14 T 28-03-2018 ALX04_RS04515 fbd5084e9b58ace49fbeeb321bf9cc9c 380 Gene3D G3DSA:2.60.260.20 204 264 2.7E-16 T 28-03-2018 ALX04_RS04515 fbd5084e9b58ace49fbeeb321bf9cc9c 380 Hamap MF_01152 Chaperone protein DnaJ [dnaJ]. 2 380 38.89 T 28-03-2018 IPR012724 Chaperone DnaJ GO:0005524|GO:0006457|GO:0009408|GO:0051082 ALX04_RS04515 fbd5084e9b58ace49fbeeb321bf9cc9c 380 ProSitePatterns PS00636 Nt-dnaJ domain signature. 46 65 - T 28-03-2018 IPR018253 DnaJ domain, conserved site ALX04_RS04515 fbd5084e9b58ace49fbeeb321bf9cc9c 380 Pfam PF01556 DnaJ C terminal domain 126 343 2.0E-39 T 28-03-2018 IPR002939 Chaperone DnaJ, C-terminal ALX04_RS04515 fbd5084e9b58ace49fbeeb321bf9cc9c 380 PRINTS PR00625 DnaJ domain signature 7 25 5.9E-30 T 28-03-2018 IPR001623 DnaJ domain ALX04_RS04515 fbd5084e9b58ace49fbeeb321bf9cc9c 380 PRINTS PR00625 DnaJ domain signature 61 80 5.9E-30 T 28-03-2018 IPR001623 DnaJ domain ALX04_RS04515 fbd5084e9b58ace49fbeeb321bf9cc9c 380 PRINTS PR00625 DnaJ domain signature 25 40 5.9E-30 T 28-03-2018 IPR001623 DnaJ domain ALX04_RS04515 fbd5084e9b58ace49fbeeb321bf9cc9c 380 PRINTS PR00625 DnaJ domain signature 41 61 5.9E-30 T 28-03-2018 IPR001623 DnaJ domain ALX04_RS11080 373915e6cd64320ccf9eb1b099378807 309 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 3.2E-8 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 ALX04_RS11080 373915e6cd64320ccf9eb1b099378807 309 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 3.2E-8 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 ALX04_RS11080 373915e6cd64320ccf9eb1b099378807 309 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 3.2E-8 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 ALX04_RS11080 373915e6cd64320ccf9eb1b099378807 309 Gene3D G3DSA:3.40.190.10 184 272 6.0E-22 T 28-03-2018 ALX04_RS11080 373915e6cd64320ccf9eb1b099378807 309 SUPERFAMILY SSF46785 1 83 1.14E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS11080 373915e6cd64320ccf9eb1b099378807 309 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 61 1.8E-19 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 ALX04_RS11080 373915e6cd64320ccf9eb1b099378807 309 Gene3D G3DSA:3.40.190.10 89 183 1.2E-15 T 28-03-2018 ALX04_RS11080 373915e6cd64320ccf9eb1b099378807 309 SUPERFAMILY SSF53850 89 302 1.09E-37 T 28-03-2018 ALX04_RS11080 373915e6cd64320ccf9eb1b099378807 309 Gene3D G3DSA:1.10.10.10 1 83 9.8E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS11080 373915e6cd64320ccf9eb1b099378807 309 Pfam PF03466 LysR substrate binding domain 89 298 4.6E-38 T 28-03-2018 IPR005119 LysR, substrate-binding ALX04_RS00745 54a76ca13bb2b6e2ba019d7175fb6fe5 462 Gene3D G3DSA:3.50.50.60 15 280 2.2E-45 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ALX04_RS00745 54a76ca13bb2b6e2ba019d7175fb6fe5 462 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 21 40 1.3E-6 T 28-03-2018 ALX04_RS00745 54a76ca13bb2b6e2ba019d7175fb6fe5 462 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 407 429 1.3E-6 T 28-03-2018 ALX04_RS00745 54a76ca13bb2b6e2ba019d7175fb6fe5 462 Gene3D G3DSA:3.50.50.60 385 462 0.0021 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ALX04_RS00745 54a76ca13bb2b6e2ba019d7175fb6fe5 462 SUPERFAMILY SSF51905 5 274 9.15E-60 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ALX04_RS00745 54a76ca13bb2b6e2ba019d7175fb6fe5 462 SUPERFAMILY SSF51905 402 461 9.15E-60 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ALX04_RS00745 54a76ca13bb2b6e2ba019d7175fb6fe5 462 Gene3D G3DSA:3.90.700.10 281 384 3.3E-28 T 28-03-2018 ALX04_RS00745 54a76ca13bb2b6e2ba019d7175fb6fe5 462 Pfam PF00890 FAD binding domain 20 443 4.5E-91 T 28-03-2018 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 ALX04_RS00745 54a76ca13bb2b6e2ba019d7175fb6fe5 462 SUPERFAMILY SSF56425 250 398 2.99E-42 T 28-03-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 ALX04_RS00745 54a76ca13bb2b6e2ba019d7175fb6fe5 462 TIGRFAM TIGR01813 flavo_cyto_c: flavocytochrome c 20 455 4.1E-146 T 28-03-2018 IPR010960 Flavocytochrome c GO:0000104|GO:0055114 ALX04_RS14810 168ec782cc86bf6fb321359df989886f 478 Gene3D G3DSA:3.40.190.10 21 141 4.5E-37 T 28-03-2018 ALX04_RS14810 168ec782cc86bf6fb321359df989886f 478 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 294 477 3.0E-20 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 ALX04_RS14810 168ec782cc86bf6fb321359df989886f 478 Gene3D G3DSA:3.40.190.10 142 264 5.1E-16 T 28-03-2018 ALX04_RS14810 168ec782cc86bf6fb321359df989886f 478 Gene3D G3DSA:1.10.3720.10 268 478 2.9E-41 T 28-03-2018 ALX04_RS14810 168ec782cc86bf6fb321359df989886f 478 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 31 248 2.1E-56 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF ALX04_RS14810 168ec782cc86bf6fb321359df989886f 478 SUPERFAMILY SSF53850 1 249 1.56E-63 T 28-03-2018 ALX04_RS14810 168ec782cc86bf6fb321359df989886f 478 SMART SM00079 29 249 0.0011 T 28-03-2018 IPR001320 Ionotropic glutamate receptor GO:0004970|GO:0016020 ALX04_RS14810 168ec782cc86bf6fb321359df989886f 478 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 272 371 2.4E-21 T 28-03-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 ALX04_RS14810 168ec782cc86bf6fb321359df989886f 478 SMART SM00062 29 250 1.3E-56 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF ALX04_RS14810 168ec782cc86bf6fb321359df989886f 478 SUPERFAMILY SSF161098 274 463 1.09E-41 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 ALX04_RS07170 c9fb0f7c3494ddcafb49530d2bf39e31 396 Pfam PF00990 Diguanylate cyclase, GGDEF domain 226 386 5.1E-38 T 28-03-2018 IPR000160 GGDEF domain ALX04_RS07170 c9fb0f7c3494ddcafb49530d2bf39e31 396 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 224 389 3.4E-41 T 28-03-2018 IPR000160 GGDEF domain ALX04_RS07170 c9fb0f7c3494ddcafb49530d2bf39e31 396 Gene3D G3DSA:3.30.70.270 220 396 5.0E-44 T 28-03-2018 ALX04_RS07170 c9fb0f7c3494ddcafb49530d2bf39e31 396 SMART SM00267 212 390 3.9E-40 T 28-03-2018 IPR000160 GGDEF domain ALX04_RS07170 c9fb0f7c3494ddcafb49530d2bf39e31 396 SUPERFAMILY SSF55073 230 389 2.35E-36 T 28-03-2018 IPR029787 Nucleotide cyclase ALX04_RS09235 a4714597b03cbd42a5bced92a52fdf1c 339 Pfam PF01370 NAD dependent epimerase/dehydratase family 6 240 2.9E-17 T 28-03-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 ALX04_RS09235 a4714597b03cbd42a5bced92a52fdf1c 339 SUPERFAMILY SSF51735 2 331 4.41E-56 T 28-03-2018 IPR016040 NAD(P)-binding domain ALX04_RS09235 a4714597b03cbd42a5bced92a52fdf1c 339 Gene3D G3DSA:3.40.50.720 3 338 3.6E-40 T 28-03-2018 ALX04_RS03295 00f67ae353f7db2a726bfac13bc96131 337 Pfam PF01263 Aldose 1-epimerase 20 332 1.8E-58 T 28-03-2018 IPR008183 Aldose 1-/Glucose-6-phosphate 1-epimerase GO:0005975|GO:0016853 ALX04_RS03295 00f67ae353f7db2a726bfac13bc96131 337 SUPERFAMILY SSF74650 6 334 2.76E-80 T 28-03-2018 IPR011013 Galactose mutarotase-like domain GO:0003824|GO:0005975|GO:0030246 ALX04_RS03295 00f67ae353f7db2a726bfac13bc96131 337 Gene3D G3DSA:2.70.98.10 11 337 6.5E-69 T 28-03-2018 IPR014718 Glycoside hydrolase-type carbohydrate-binding GO:0030246 ALX04_RS14295 a6991fdfdf5e1409abf042335115122b 141 ProSitePatterns PS00359 Ribosomal protein L11 signature. 126 141 - T 28-03-2018 IPR020785 Ribosomal protein L11, conserved site GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 ALX04_RS14295 a6991fdfdf5e1409abf042335115122b 141 Gene3D G3DSA:1.10.10.250 72 140 4.1E-26 T 28-03-2018 IPR020783 Ribosomal protein L11, C-terminal GO:0003735|GO:0005840|GO:0006412 ALX04_RS14295 a6991fdfdf5e1409abf042335115122b 141 TIGRFAM TIGR01632 L11_bact: ribosomal protein uL11 3 140 1.3E-64 T 28-03-2018 IPR006519 Ribosomal protein L11, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 ALX04_RS14295 a6991fdfdf5e1409abf042335115122b 141 Gene3D G3DSA:3.30.1550.10 3 71 3.3E-36 T 28-03-2018 IPR020784 Ribosomal protein L11, N-terminal ALX04_RS14295 a6991fdfdf5e1409abf042335115122b 141 SUPERFAMILY SSF46906 67 140 6.28E-28 T 28-03-2018 IPR020783 Ribosomal protein L11, C-terminal GO:0003735|GO:0005840|GO:0006412 ALX04_RS14295 a6991fdfdf5e1409abf042335115122b 141 ProDom PD001367 RIBOSOMAL RIBONUCLEOPROTEIN L11 RRNA-BINDING RNA-BINDING METHYLATION 50S L11 BACTERIAL CHLOROPLAST 36 73 5.0E-16 T 28-03-2018 ALX04_RS14295 a6991fdfdf5e1409abf042335115122b 141 SUPERFAMILY SSF54747 3 72 3.14E-30 T 28-03-2018 IPR020784 Ribosomal protein L11, N-terminal ALX04_RS14295 a6991fdfdf5e1409abf042335115122b 141 Pfam PF03946 Ribosomal protein L11, N-terminal domain 9 66 3.5E-31 T 28-03-2018 IPR020784 Ribosomal protein L11, N-terminal ALX04_RS14295 a6991fdfdf5e1409abf042335115122b 141 Hamap MF_00736 50S ribosomal protein L11 [rplK]. 5 141 31.91 T 28-03-2018 IPR000911 Ribosomal protein L11/L12 GO:0003735|GO:0005840|GO:0006412 ALX04_RS14295 a6991fdfdf5e1409abf042335115122b 141 Pfam PF00298 Ribosomal protein L11, RNA binding domain 71 139 7.6E-26 T 28-03-2018 IPR020783 Ribosomal protein L11, C-terminal GO:0003735|GO:0005840|GO:0006412 ALX04_RS14295 a6991fdfdf5e1409abf042335115122b 141 SMART SM00649 9 140 1.5E-87 T 28-03-2018 IPR000911 Ribosomal protein L11/L12 GO:0003735|GO:0005840|GO:0006412 ALX04_RS00480 7d1f80f1726593d84d3efd61ea5d3b8c 431 Pfam PF00344 SecY translocase 68 414 5.8E-100 T 28-03-2018 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 ALX04_RS00480 7d1f80f1726593d84d3efd61ea5d3b8c 431 ProSitePatterns PS00755 Protein secY signature 1. 68 87 - T 28-03-2018 IPR030659 SecY conserved site Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 ALX04_RS00480 7d1f80f1726593d84d3efd61ea5d3b8c 431 Hamap MF_01465 Protein translocase subunit SecY [secY]. 5 430 27.121 T 28-03-2018 IPR026593 Protein translocase subunit SecY ALX04_RS00480 7d1f80f1726593d84d3efd61ea5d3b8c 431 Gene3D G3DSA:1.10.3370.10 1 431 6.4E-138 T 28-03-2018 ALX04_RS00480 7d1f80f1726593d84d3efd61ea5d3b8c 431 TIGRFAM TIGR00967 3a0501s007: preprotein translocase, SecY subunit 15 425 4.5E-134 T 28-03-2018 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 ALX04_RS00480 7d1f80f1726593d84d3efd61ea5d3b8c 431 PRINTS PR00303 Preprotein translocase SecY subunit signature 310 332 9.8E-94 T 28-03-2018 ALX04_RS00480 7d1f80f1726593d84d3efd61ea5d3b8c 431 PRINTS PR00303 Preprotein translocase SecY subunit signature 146 171 9.8E-94 T 28-03-2018 ALX04_RS00480 7d1f80f1726593d84d3efd61ea5d3b8c 431 PRINTS PR00303 Preprotein translocase SecY subunit signature 399 417 9.8E-94 T 28-03-2018 ALX04_RS00480 7d1f80f1726593d84d3efd61ea5d3b8c 431 PRINTS PR00303 Preprotein translocase SecY subunit signature 109 132 9.8E-94 T 28-03-2018 ALX04_RS00480 7d1f80f1726593d84d3efd61ea5d3b8c 431 PRINTS PR00303 Preprotein translocase SecY subunit signature 266 285 9.8E-94 T 28-03-2018 ALX04_RS00480 7d1f80f1726593d84d3efd61ea5d3b8c 431 PRINTS PR00303 Preprotein translocase SecY subunit signature 365 383 9.8E-94 T 28-03-2018 ALX04_RS00480 7d1f80f1726593d84d3efd61ea5d3b8c 431 PRINTS PR00303 Preprotein translocase SecY subunit signature 172 195 9.8E-94 T 28-03-2018 ALX04_RS00480 7d1f80f1726593d84d3efd61ea5d3b8c 431 PRINTS PR00303 Preprotein translocase SecY subunit signature 18 36 9.8E-94 T 28-03-2018 ALX04_RS00480 7d1f80f1726593d84d3efd61ea5d3b8c 431 PRINTS PR00303 Preprotein translocase SecY subunit signature 67 87 9.8E-94 T 28-03-2018 ALX04_RS00480 7d1f80f1726593d84d3efd61ea5d3b8c 431 ProSitePatterns PS00756 Protein secY signature 2. 165 182 - T 28-03-2018 IPR030659 SecY conserved site Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 ALX04_RS00480 7d1f80f1726593d84d3efd61ea5d3b8c 431 PIRSF PIRSF004557 1 430 3.8E-116 T 28-03-2018 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 ALX04_RS00480 7d1f80f1726593d84d3efd61ea5d3b8c 431 SUPERFAMILY SSF103491 2 421 6.93E-122 T 28-03-2018 IPR023201 SecY subunit domain Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 ALX04_RS06845 0b9a68e6bf70cec6c38ac085b6f54a54 321 Gene3D G3DSA:3.40.50.300 10 317 1.2E-32 T 28-03-2018 ALX04_RS06845 0b9a68e6bf70cec6c38ac085b6f54a54 321 Pfam PF13614 AAA domain 12 225 1.2E-34 T 28-03-2018 IPR025669 AAA domain ALX04_RS06845 0b9a68e6bf70cec6c38ac085b6f54a54 321 SUPERFAMILY SSF52540 11 63 1.85E-30 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase ALX04_RS06845 0b9a68e6bf70cec6c38ac085b6f54a54 321 SUPERFAMILY SSF52540 110 261 1.85E-30 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase ALX04_RS00845 90c5a5e718155f1202f0dfb0396b0ccd 195 Hamap MF_01184 Xanthine phosphoribosyltransferase [xpt]. 1 189 41.159 T 28-03-2018 IPR010079 Xanthine phosphoribosyltransferase GO:0016763|GO:0043101|GO:0046110 KEGG: 00230+2.4.2.22 ALX04_RS00845 90c5a5e718155f1202f0dfb0396b0ccd 195 Gene3D G3DSA:3.40.50.2020 3 188 1.2E-17 T 28-03-2018 ALX04_RS00845 90c5a5e718155f1202f0dfb0396b0ccd 195 TIGRFAM TIGR01744 XPRTase: xanthine phosphoribosyltransferase 1 190 2.4E-79 T 28-03-2018 IPR010079 Xanthine phosphoribosyltransferase GO:0016763|GO:0043101|GO:0046110 KEGG: 00230+2.4.2.22 ALX04_RS00845 90c5a5e718155f1202f0dfb0396b0ccd 195 SUPERFAMILY SSF53271 1 187 1.75E-42 T 28-03-2018 IPR029057 Phosphoribosyltransferase-like ALX04_RS14695 bec32c4e4da39e3fe1e51b0c2d391f1a 467 PRINTS PR00145 Argininosuccinate lyase family signature 104 126 1.5E-68 T 28-03-2018 ALX04_RS14695 bec32c4e4da39e3fe1e51b0c2d391f1a 467 PRINTS PR00145 Argininosuccinate lyase family signature 234 258 1.5E-68 T 28-03-2018 ALX04_RS14695 bec32c4e4da39e3fe1e51b0c2d391f1a 467 PRINTS PR00145 Argininosuccinate lyase family signature 145 165 1.5E-68 T 28-03-2018 ALX04_RS14695 bec32c4e4da39e3fe1e51b0c2d391f1a 467 PRINTS PR00145 Argininosuccinate lyase family signature 196 212 1.5E-68 T 28-03-2018 ALX04_RS14695 bec32c4e4da39e3fe1e51b0c2d391f1a 467 PRINTS PR00145 Argininosuccinate lyase family signature 313 332 1.5E-68 T 28-03-2018 ALX04_RS14695 bec32c4e4da39e3fe1e51b0c2d391f1a 467 PRINTS PR00145 Argininosuccinate lyase family signature 278 294 1.5E-68 T 28-03-2018 ALX04_RS14695 bec32c4e4da39e3fe1e51b0c2d391f1a 467 Gene3D G3DSA:1.10.40.30 378 435 1.0E-21 T 28-03-2018 ALX04_RS14695 bec32c4e4da39e3fe1e51b0c2d391f1a 467 PRINTS PR00149 Fumarate lyase superfamily signature 234 261 2.1E-28 T 28-03-2018 IPR000362 Fumarate lyase family ALX04_RS14695 bec32c4e4da39e3fe1e51b0c2d391f1a 467 PRINTS PR00149 Fumarate lyase superfamily signature 150 168 2.1E-28 T 28-03-2018 IPR000362 Fumarate lyase family ALX04_RS14695 bec32c4e4da39e3fe1e51b0c2d391f1a 467 PRINTS PR00149 Fumarate lyase superfamily signature 278 294 2.1E-28 T 28-03-2018 IPR000362 Fumarate lyase family ALX04_RS14695 bec32c4e4da39e3fe1e51b0c2d391f1a 467 PRINTS PR00149 Fumarate lyase superfamily signature 105 123 2.1E-28 T 28-03-2018 IPR000362 Fumarate lyase family ALX04_RS14695 bec32c4e4da39e3fe1e51b0c2d391f1a 467 Gene3D G3DSA:1.20.200.10 110 377 6.7E-93 T 28-03-2018 ALX04_RS14695 bec32c4e4da39e3fe1e51b0c2d391f1a 467 Hamap MF_00006 Argininosuccinate lyase [argH]. 5 456 42.968 T 28-03-2018 IPR009049 Argininosuccinate lyase GO:0004056|GO:0042450 KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 ALX04_RS14695 bec32c4e4da39e3fe1e51b0c2d391f1a 467 ProSitePatterns PS00163 Fumarate lyases signature. 278 287 - T 28-03-2018 IPR020557 Fumarate lyase, conserved site GO:0003824 ALX04_RS14695 bec32c4e4da39e3fe1e51b0c2d391f1a 467 Pfam PF14698 Argininosuccinate lyase C-terminal 366 433 2.0E-21 T 28-03-2018 IPR029419 Argininosuccinate lyase, C-terminal KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 ALX04_RS14695 bec32c4e4da39e3fe1e51b0c2d391f1a 467 TIGRFAM TIGR00838 argH: argininosuccinate lyase 6 458 9.8E-193 T 28-03-2018 IPR009049 Argininosuccinate lyase GO:0004056|GO:0042450 KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 ALX04_RS14695 bec32c4e4da39e3fe1e51b0c2d391f1a 467 Pfam PF00206 Lyase 9 303 6.7E-74 T 28-03-2018 IPR022761 Fumarate lyase, N-terminal ALX04_RS14695 bec32c4e4da39e3fe1e51b0c2d391f1a 467 SUPERFAMILY SSF48557 6 458 6.13E-149 T 28-03-2018 IPR008948 L-Aspartase-like GO:0003824 ALX04_RS14695 bec32c4e4da39e3fe1e51b0c2d391f1a 467 Gene3D G3DSA:1.10.275.10 5 109 6.1E-36 T 28-03-2018 IPR024083 Fumarase/histidase, N-terminal ALX04_RS08735 b9e2dc69cc3206c2bee4a716b9447eb8 595 ProSitePatterns PS00211 ABC transporters family signature. 491 505 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 ALX04_RS08735 b9e2dc69cc3206c2bee4a716b9447eb8 595 SUPERFAMILY SSF52540 347 589 5.12E-84 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase ALX04_RS08735 b9e2dc69cc3206c2bee4a716b9447eb8 595 Gene3D G3DSA:1.20.1560.10 15 339 3.0E-60 T 28-03-2018 ALX04_RS08735 b9e2dc69cc3206c2bee4a716b9447eb8 595 Pfam PF00664 ABC transporter transmembrane region 36 308 1.2E-31 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 ALX04_RS08735 b9e2dc69cc3206c2bee4a716b9447eb8 595 SMART SM00382 379 571 1.3E-12 T 28-03-2018 IPR003593 AAA+ ATPase domain ALX04_RS08735 b9e2dc69cc3206c2bee4a716b9447eb8 595 SUPERFAMILY SSF90123 22 335 1.96E-67 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 ALX04_RS08735 b9e2dc69cc3206c2bee4a716b9447eb8 595 Gene3D G3DSA:3.40.50.300 340 595 1.3E-68 T 28-03-2018 ALX04_RS08735 b9e2dc69cc3206c2bee4a716b9447eb8 595 Pfam PF00005 ABC transporter 370 519 9.9E-30 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 ALX04_RS14895 c576461ad0bb113e9394ce4c1d10d3d1 451 Gene3D G3DSA:3.30.310.50 377 449 2.3E-20 T 28-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 ALX04_RS14895 c576461ad0bb113e9394ce4c1d10d3d1 451 Gene3D G3DSA:3.40.120.10 1 165 8.5E-45 T 28-03-2018 ALX04_RS14895 c576461ad0bb113e9394ce4c1d10d3d1 451 TIGRFAM TIGR01455 glmM: phosphoglucosamine mutase 4 445 8.1E-179 T 28-03-2018 IPR006352 Phosphoglucosamine mutase, bacterial type GO:0000287|GO:0005975|GO:0008966 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 ALX04_RS14895 c576461ad0bb113e9394ce4c1d10d3d1 451 ProSitePatterns PS00710 Phosphoglucomutase and phosphomannomutase phosphoserine signature. 97 106 - T 28-03-2018 IPR016066 Alpha-D-phosphohexomutase, conserved site GO:0000287 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 ALX04_RS14895 c576461ad0bb113e9394ce4c1d10d3d1 451 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 260 370 4.0E-35 T 28-03-2018 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 ALX04_RS14895 c576461ad0bb113e9394ce4c1d10d3d1 451 SUPERFAMILY SSF55957 360 448 8.76E-25 T 28-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 ALX04_RS14895 c576461ad0bb113e9394ce4c1d10d3d1 451 SUPERFAMILY SSF53738 2 182 1.26E-44 T 28-03-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 ALX04_RS14895 c576461ad0bb113e9394ce4c1d10d3d1 451 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 2 138 3.0E-42 T 28-03-2018 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 ALX04_RS14895 c576461ad0bb113e9394ce4c1d10d3d1 451 SUPERFAMILY SSF53738 162 259 9.81E-22 T 28-03-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 ALX04_RS14895 c576461ad0bb113e9394ce4c1d10d3d1 451 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 162 256 2.3E-13 T 28-03-2018 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 ALX04_RS14895 c576461ad0bb113e9394ce4c1d10d3d1 451 SUPERFAMILY SSF53738 260 368 3.92E-33 T 28-03-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 ALX04_RS14895 c576461ad0bb113e9394ce4c1d10d3d1 451 Hamap MF_01554_B Phosphoglucosamine mutase [glmM]. 1 447 43.176 T 28-03-2018 IPR006352 Phosphoglucosamine mutase, bacterial type GO:0000287|GO:0005975|GO:0008966 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 ALX04_RS14895 c576461ad0bb113e9394ce4c1d10d3d1 451 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 96 110 1.4E-12 T 28-03-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 ALX04_RS14895 c576461ad0bb113e9394ce4c1d10d3d1 451 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 176 195 1.4E-12 T 28-03-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 ALX04_RS14895 c576461ad0bb113e9394ce4c1d10d3d1 451 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 236 251 1.4E-12 T 28-03-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 ALX04_RS14895 c576461ad0bb113e9394ce4c1d10d3d1 451 Gene3D G3DSA:3.40.120.10 265 376 3.6E-34 T 28-03-2018 ALX04_RS14895 c576461ad0bb113e9394ce4c1d10d3d1 451 Gene3D G3DSA:3.40.120.10 166 264 1.4E-19 T 28-03-2018 ALX04_RS14895 c576461ad0bb113e9394ce4c1d10d3d1 451 ProSitePatterns PS00018 EF-hand calcium-binding domain. 243 255 - T 28-03-2018 IPR018247 EF-Hand 1, calcium-binding site ALX04_RS14895 c576461ad0bb113e9394ce4c1d10d3d1 451 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 376 444 2.9E-17 T 28-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 ALX04_RS01350 b9ebb17f4c4a5bbfa4a1ecf959c5a74b 293 SUPERFAMILY SSF46785 1 86 1.5E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS01350 b9ebb17f4c4a5bbfa4a1ecf959c5a74b 293 Gene3D G3DSA:3.40.190.10 88 176 6.5E-14 T 28-03-2018 ALX04_RS01350 b9ebb17f4c4a5bbfa4a1ecf959c5a74b 293 SUPERFAMILY SSF53850 88 289 4.03E-28 T 28-03-2018 ALX04_RS01350 b9ebb17f4c4a5bbfa4a1ecf959c5a74b 293 Gene3D G3DSA:3.40.190.10 177 264 3.5E-14 T 28-03-2018 ALX04_RS01350 b9ebb17f4c4a5bbfa4a1ecf959c5a74b 293 Gene3D G3DSA:1.10.10.10 1 83 9.8E-23 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS01350 b9ebb17f4c4a5bbfa4a1ecf959c5a74b 293 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 62 1.1E-21 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 ALX04_RS01350 b9ebb17f4c4a5bbfa4a1ecf959c5a74b 293 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 1.2E-9 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 ALX04_RS01350 b9ebb17f4c4a5bbfa4a1ecf959c5a74b 293 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 1.2E-9 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 ALX04_RS01350 b9ebb17f4c4a5bbfa4a1ecf959c5a74b 293 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 1.2E-9 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 ALX04_RS01350 b9ebb17f4c4a5bbfa4a1ecf959c5a74b 293 Pfam PF03466 LysR substrate binding domain 88 289 6.3E-32 T 28-03-2018 IPR005119 LysR, substrate-binding ALX04_RS06030 0b75a0582449459279b7445aed9f90ae 377 Pfam PF11799 impB/mucB/samB family C-terminal domain 250 361 2.2E-16 T 28-03-2018 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 ALX04_RS06030 0b75a0582449459279b7445aed9f90ae 377 SUPERFAMILY SSF56672 5 251 1.42E-87 T 28-03-2018 ALX04_RS06030 0b75a0582449459279b7445aed9f90ae 377 SUPERFAMILY SSF100879 258 371 7.69E-22 T 28-03-2018 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 ALX04_RS06030 0b75a0582449459279b7445aed9f90ae 377 Gene3D G3DSA:3.30.1490.100 255 372 1.1E-21 T 28-03-2018 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 ALX04_RS06030 0b75a0582449459279b7445aed9f90ae 377 Gene3D G3DSA:3.30.70.270 132 187 2.0E-17 T 28-03-2018 ALX04_RS06030 0b75a0582449459279b7445aed9f90ae 377 Gene3D G3DSA:3.30.70.270 58 131 3.7E-22 T 28-03-2018 ALX04_RS06030 0b75a0582449459279b7445aed9f90ae 377 Hamap MF_01113 DNA polymerase IV [dinB]. 15 370 36.12 T 28-03-2018 IPR022880 DNA polymerase IV GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5655862|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210 ALX04_RS06030 0b75a0582449459279b7445aed9f90ae 377 Pfam PF00817 impB/mucB/samB family 21 171 2.3E-48 T 28-03-2018 IPR001126 UmuC domain GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 ALX04_RS06030 0b75a0582449459279b7445aed9f90ae 377 Gene3D G3DSA:1.10.150.20 188 254 6.6E-15 T 28-03-2018 ALX04_RS05575 53faa5ccf5b92aa7a5327eddb5c3c54d 795 Pfam PF09397 Ftsk gamma domain 721 780 7.1E-30 T 28-03-2018 IPR018541 FtsK gamma domain ALX04_RS05575 53faa5ccf5b92aa7a5327eddb5c3c54d 795 SMART SM00382 457 639 0.0038 T 28-03-2018 IPR003593 AAA+ ATPase domain ALX04_RS05575 53faa5ccf5b92aa7a5327eddb5c3c54d 795 Pfam PF01580 FtsK/SpoIIIE family 429 618 1.1E-58 T 28-03-2018 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 ALX04_RS05575 53faa5ccf5b92aa7a5327eddb5c3c54d 795 SUPERFAMILY SSF52540 397 690 6.38E-46 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase ALX04_RS05575 53faa5ccf5b92aa7a5327eddb5c3c54d 795 Gene3D G3DSA:1.10.10.10 735 775 6.4E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS05575 53faa5ccf5b92aa7a5327eddb5c3c54d 795 Gene3D G3DSA:3.40.50.300 189 734 8.6E-54 T 28-03-2018 ALX04_RS05575 53faa5ccf5b92aa7a5327eddb5c3c54d 795 SUPERFAMILY SSF46785 720 783 4.08E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS05575 53faa5ccf5b92aa7a5327eddb5c3c54d 795 SMART SM00843 719 784 7.1E-38 T 28-03-2018 IPR018541 FtsK gamma domain ALX04_RS02245 79db56032ddbc47415704542c14d9a26 436 SUPERFAMILY SSF53623 90 296 1.83E-57 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 ALX04_RS02245 79db56032ddbc47415704542c14d9a26 436 Pfam PF02875 Mur ligase family, glutamate ligase domain 298 380 6.7E-19 T 28-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 ALX04_RS02245 79db56032ddbc47415704542c14d9a26 436 Gene3D G3DSA:3.40.1190.10 93 298 2.1E-38 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 ALX04_RS02245 79db56032ddbc47415704542c14d9a26 436 SUPERFAMILY SSF51984 7 91 3.34E-20 T 28-03-2018 ALX04_RS02245 79db56032ddbc47415704542c14d9a26 436 Gene3D G3DSA:3.90.190.20 299 436 5.9E-28 T 28-03-2018 ALX04_RS02245 79db56032ddbc47415704542c14d9a26 436 Pfam PF01225 Mur ligase family, catalytic domain 7 104 5.6E-25 T 28-03-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 ALX04_RS02245 79db56032ddbc47415704542c14d9a26 436 Gene3D G3DSA:3.40.50.720 3 92 1.3E-5 T 28-03-2018 ALX04_RS02245 79db56032ddbc47415704542c14d9a26 436 Pfam PF08245 Mur ligase middle domain 109 277 1.7E-23 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 ALX04_RS02245 79db56032ddbc47415704542c14d9a26 436 Hamap MF_00046 UDP-N-acetylmuramate--L-alanine ligase [murC]. 4 436 34.104 T 28-03-2018 IPR005758 UDP-N-acetylmuramate--L-alanine ligase GO:0008763|GO:0009252 KEGG: 00471+6.3.2.8|KEGG: 00550+6.3.2.8|MetaCyc: PWY-6386|MetaCyc: PWY-6387 ALX04_RS02245 79db56032ddbc47415704542c14d9a26 436 SUPERFAMILY SSF53244 297 432 1.32E-36 T 28-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 ALX04_RS02245 79db56032ddbc47415704542c14d9a26 436 TIGRFAM TIGR01082 murC: UDP-N-acetylmuramate--L-alanine ligase 7 426 8.7E-130 T 28-03-2018 IPR005758 UDP-N-acetylmuramate--L-alanine ligase GO:0008763|GO:0009252 KEGG: 00471+6.3.2.8|KEGG: 00550+6.3.2.8|MetaCyc: PWY-6386|MetaCyc: PWY-6387 ALX04_RS13175 2d0ecdbd0996d4aa59b26400260ef609 148 Gene3D G3DSA:3.30.420.10 8 137 8.4E-7 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 ALX04_RS13175 2d0ecdbd0996d4aa59b26400260ef609 148 SUPERFAMILY SSF53098 22 128 2.58E-10 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 ALX04_RS02520 b864cf123c846292cca2dc13bf475123 348 Hamap MF_00281 Phenylalanine--tRNA ligase alpha subunit [pheS]. 11 344 46.668 T 28-03-2018 IPR022911 Phenylalanine-tRNA ligase alpha chain 1, bacterial GO:0004826 KEGG: 00970+6.1.1.20 ALX04_RS02520 b864cf123c846292cca2dc13bf475123 348 SUPERFAMILY SSF55681 94 344 5.97E-78 T 28-03-2018 ALX04_RS02520 b864cf123c846292cca2dc13bf475123 348 Gene3D G3DSA:3.30.930.10 10 348 8.4E-89 T 28-03-2018 ALX04_RS02520 b864cf123c846292cca2dc13bf475123 348 SUPERFAMILY SSF46589 15 102 1.57E-21 T 28-03-2018 IPR010978 tRNA-binding arm GO:0000166 ALX04_RS02520 b864cf123c846292cca2dc13bf475123 348 Pfam PF02912 Aminoacyl tRNA synthetase class II, N-terminal domain 24 90 3.5E-25 T 28-03-2018 IPR004188 Phenylalanine-tRNA ligase, class II, N-terminal GO:0000166|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 ALX04_RS02520 b864cf123c846292cca2dc13bf475123 348 Pfam PF01409 tRNA synthetases class II core domain (F) 94 344 7.3E-101 T 28-03-2018 IPR002319 Phenylalanyl-tRNA synthetase GO:0000049|GO:0004812|GO:0005524|GO:0005737|GO:0043039 KEGG: 00970+6.1.1.20 ALX04_RS11880 2ed23afc62a006c8946836132c921c1b 672 Pfam PF03764 Elongation factor G, domain IV 403 514 3.3E-18 T 28-03-2018 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 ALX04_RS11880 2ed23afc62a006c8946836132c921c1b 672 PRINTS PR00315 GTP-binding elongation factor signature 87 98 1.1E-12 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 ALX04_RS11880 2ed23afc62a006c8946836132c921c1b 672 PRINTS PR00315 GTP-binding elongation factor signature 51 59 1.1E-12 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 ALX04_RS11880 2ed23afc62a006c8946836132c921c1b 672 PRINTS PR00315 GTP-binding elongation factor signature 71 81 1.1E-12 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 ALX04_RS11880 2ed23afc62a006c8946836132c921c1b 672 PRINTS PR00315 GTP-binding elongation factor signature 123 132 1.1E-12 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 ALX04_RS11880 2ed23afc62a006c8946836132c921c1b 672 PRINTS PR00315 GTP-binding elongation factor signature 5 18 1.1E-12 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 ALX04_RS11880 2ed23afc62a006c8946836132c921c1b 672 Gene3D G3DSA:2.40.30.10 241 326 4.6E-15 T 28-03-2018 ALX04_RS11880 2ed23afc62a006c8946836132c921c1b 672 SUPERFAMILY SSF52540 6 230 5.2E-64 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase ALX04_RS11880 2ed23afc62a006c8946836132c921c1b 672 Pfam PF00009 Elongation factor Tu GTP binding domain 6 231 2.9E-50 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 ALX04_RS11880 2ed23afc62a006c8946836132c921c1b 672 Gene3D G3DSA:3.30.230.10 416 531 6.3E-40 T 28-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup ALX04_RS11880 2ed23afc62a006c8946836132c921c1b 672 Pfam PF14492 Elongation Factor G, domain II 330 400 4.0E-7 T 28-03-2018 ALX04_RS11880 2ed23afc62a006c8946836132c921c1b 672 SUPERFAMILY SSF54980 524 614 2.49E-15 T 28-03-2018 IPR035647 EF-G domain III/V-like ALX04_RS11880 2ed23afc62a006c8946836132c921c1b 672 Gene3D G3DSA:3.40.50.300 1 67 1.2E-8 T 28-03-2018 ALX04_RS11880 2ed23afc62a006c8946836132c921c1b 672 SMART SM00838 523 617 6.2E-4 T 28-03-2018 IPR000640 Elongation factor EFG, domain V-like ALX04_RS11880 2ed23afc62a006c8946836132c921c1b 672 SMART SM00889 403 517 3.0E-25 T 28-03-2018 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 ALX04_RS11880 2ed23afc62a006c8946836132c921c1b 672 Gene3D G3DSA:3.40.50.300 68 230 3.7E-28 T 28-03-2018 ALX04_RS11880 2ed23afc62a006c8946836132c921c1b 672 SUPERFAMILY SSF54211 404 514 6.07E-26 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold ALX04_RS11880 2ed23afc62a006c8946836132c921c1b 672 SUPERFAMILY SSF54980 330 404 3.96E-12 T 28-03-2018 IPR035647 EF-G domain III/V-like ALX04_RS11880 2ed23afc62a006c8946836132c921c1b 672 Gene3D G3DSA:3.30.70.240 532 614 4.7E-15 T 28-03-2018 ALX04_RS11880 2ed23afc62a006c8946836132c921c1b 672 PRINTS PR01037 Tetracycline resistance protein TetO/TetQ/TetM family signature 261 287 2.2E-13 T 28-03-2018 ALX04_RS11880 2ed23afc62a006c8946836132c921c1b 672 PRINTS PR01037 Tetracycline resistance protein TetO/TetQ/TetM family signature 439 453 2.2E-13 T 28-03-2018 ALX04_RS11880 2ed23afc62a006c8946836132c921c1b 672 PRINTS PR01037 Tetracycline resistance protein TetO/TetQ/TetM family signature 209 231 2.2E-13 T 28-03-2018 ALX04_RS11880 2ed23afc62a006c8946836132c921c1b 672 PRINTS PR01037 Tetracycline resistance protein TetO/TetQ/TetM family signature 109 132 2.2E-13 T 28-03-2018 ALX04_RS11880 2ed23afc62a006c8946836132c921c1b 672 Gene3D G3DSA:3.30.70.870 327 415 1.8E-16 T 28-03-2018 ALX04_RS11880 2ed23afc62a006c8946836132c921c1b 672 SUPERFAMILY SSF50447 222 320 6.98E-12 T 28-03-2018 IPR009000 Translation protein, beta-barrel domain ALX04_RS11880 2ed23afc62a006c8946836132c921c1b 672 Pfam PF00679 Elongation factor G C-terminus 523 613 1.1E-17 T 28-03-2018 IPR000640 Elongation factor EFG, domain V-like ALX04_RS11880 2ed23afc62a006c8946836132c921c1b 672 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 1 136 1.3E-25 T 28-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 ALX04_RS14670 a5488f57c84c8d9587c541efc4474860 215 ProDom PD353566 UPF0207 HYDROLASE HD PHOSPHOHYDROLASE METAL-DEPENDENT SUBDOMAIN YFBR PHOSPHOHYDROLASE NUCLEOTIDE-BINDING NUCLEOSIDE 79 187 1.0E-4 T 28-03-2018 ALX04_RS14670 a5488f57c84c8d9587c541efc4474860 215 SUPERFAMILY SSF109604 3 188 5.34E-32 T 28-03-2018 ALX04_RS14670 a5488f57c84c8d9587c541efc4474860 215 Pfam PF12917 HD containing hydrolase-like enzyme 1 209 2.1E-92 T 28-03-2018 IPR027366 HD containing hydrolase-like enzyme ALX04_RS14670 a5488f57c84c8d9587c541efc4474860 215 Gene3D G3DSA:1.10.3210.10 1 214 1.5E-43 T 28-03-2018 ALX04_RS11325 37028e9b59607796f51880a53107c345 228 SUPERFAMILY SSF51366 8 226 6.83E-60 T 28-03-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 ALX04_RS11325 37028e9b59607796f51880a53107c345 228 Gene3D G3DSA:3.20.20.70 1 228 2.9E-40 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 ALX04_RS11325 37028e9b59607796f51880a53107c345 228 Hamap MF_01235 Putative N-acetylmannosamine-6-phosphate 2-epimerase [nanE]. 7 228 39.997 T 28-03-2018 IPR007260 Putative N-acetylmannosamine-6-phosphate epimerase GO:0006051|GO:0047465 KEGG: 00520+5.1.3.9 ALX04_RS11325 37028e9b59607796f51880a53107c345 228 Pfam PF04131 Putative N-acetylmannosamine-6-phosphate epimerase 31 227 2.2E-63 T 28-03-2018 IPR007260 Putative N-acetylmannosamine-6-phosphate epimerase GO:0006051|GO:0047465 KEGG: 00520+5.1.3.9 ALX04_RS12275 b21febdf4531fe3c480983814250f5b8 329 TIGRFAM TIGR02362 dhaK1b: probable dihydroxyacetone kinase DhaK1b subunit 2 327 9.8E-169 T 28-03-2018 IPR012735 Dihydroxyacetone kinase DhaK, subunit 1b ALX04_RS12275 b21febdf4531fe3c480983814250f5b8 329 Pfam PF02733 Dak1 domain 17 325 4.4E-85 T 28-03-2018 IPR004006 DhaK domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 ALX04_RS12275 b21febdf4531fe3c480983814250f5b8 329 Gene3D G3DSA:3.40.50.10440 11 181 1.6E-50 T 28-03-2018 ALX04_RS12275 b21febdf4531fe3c480983814250f5b8 329 SUPERFAMILY SSF82549 11 328 8.37E-98 T 28-03-2018 ALX04_RS12275 b21febdf4531fe3c480983814250f5b8 329 Gene3D G3DSA:3.30.1180.20 182 329 1.6E-37 T 28-03-2018 ALX04_RS08475 70a986a911d8843219315242993e6380 299 SUPERFAMILY SSF52540 2 224 4.19E-54 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase ALX04_RS08475 70a986a911d8843219315242993e6380 299 Gene3D G3DSA:3.40.50.300 1 286 1.7E-54 T 28-03-2018 ALX04_RS08475 70a986a911d8843219315242993e6380 299 Pfam PF13732 Domain of unknown function (DUF4162) 210 290 2.0E-16 T 28-03-2018 IPR025302 Domain of unknown function DUF4162 ALX04_RS08475 70a986a911d8843219315242993e6380 299 Pfam PF00005 ABC transporter 17 156 8.4E-26 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 ALX04_RS08475 70a986a911d8843219315242993e6380 299 SMART SM00382 26 204 3.3E-10 T 28-03-2018 IPR003593 AAA+ ATPase domain ALX04_RS08475 70a986a911d8843219315242993e6380 299 ProSitePatterns PS00211 ABC transporters family signature. 129 143 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 ALX04_RS07060 3f7756569b1971bf8265451dd8016f82 525 Pfam PF00534 Glycosyl transferases group 1 327 484 2.4E-27 T 28-03-2018 IPR001296 Glycosyl transferase, family 1 ALX04_RS07060 3f7756569b1971bf8265451dd8016f82 525 SUPERFAMILY SSF53756 277 501 4.81E-38 T 28-03-2018 ALX04_RS07060 3f7756569b1971bf8265451dd8016f82 525 Gene3D G3DSA:3.40.50.2000 325 498 3.8E-31 T 28-03-2018 ALX04_RS11875 a26d7df76da82be6f0f2c03eef5d7a53 215 Gene3D G3DSA:3.40.50.360 2 214 1.1E-24 T 28-03-2018 IPR029039 Flavoprotein-like domain ALX04_RS11875 a26d7df76da82be6f0f2c03eef5d7a53 215 Pfam PF02525 Flavodoxin-like fold 2 207 3.2E-36 T 28-03-2018 IPR003680 Flavodoxin-like fold ALX04_RS11875 a26d7df76da82be6f0f2c03eef5d7a53 215 Hamap MF_01216 FMN-dependent NADH-azoreductase [azoR]. 2 210 23.205 T 28-03-2018 IPR023048 NADH-azoreductase, FMN-dependent GO:0016661|GO:0055114 ALX04_RS11875 a26d7df76da82be6f0f2c03eef5d7a53 215 SUPERFAMILY SSF52218 1 213 1.23E-39 T 28-03-2018 IPR029039 Flavoprotein-like domain ALX04_RS02625 a3dfc88469fe03bf92b8c53c31e1205f 311 Gene3D G3DSA:1.10.287.890 203 283 1.9E-26 T 28-03-2018 ALX04_RS02625 a3dfc88469fe03bf92b8c53c31e1205f 311 Hamap MF_00185 tRNA dimethylallyltransferase [miaA]. 9 307 27.457 T 28-03-2018 IPR018022 tRNA dimethylallyltransferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781|Reactome: R-HSA-6782315|Reactome: R-HSA-6787450 ALX04_RS02625 a3dfc88469fe03bf92b8c53c31e1205f 311 TIGRFAM TIGR00174 miaA: tRNA dimethylallyltransferase 9 291 3.2E-87 T 28-03-2018 IPR018022 tRNA dimethylallyltransferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781|Reactome: R-HSA-6782315|Reactome: R-HSA-6787450 ALX04_RS02625 a3dfc88469fe03bf92b8c53c31e1205f 311 SUPERFAMILY SSF52540 149 218 1.82E-5 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase ALX04_RS02625 a3dfc88469fe03bf92b8c53c31e1205f 311 SUPERFAMILY SSF52540 7 42 1.82E-5 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase ALX04_RS02625 a3dfc88469fe03bf92b8c53c31e1205f 311 SUPERFAMILY SSF52540 10 123 1.92E-18 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase ALX04_RS02625 a3dfc88469fe03bf92b8c53c31e1205f 311 Pfam PF01715 IPP transferase 42 286 1.8E-73 T 28-03-2018 IPR018022 tRNA dimethylallyltransferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781|Reactome: R-HSA-6782315|Reactome: R-HSA-6787450 ALX04_RS02625 a3dfc88469fe03bf92b8c53c31e1205f 311 Gene3D G3DSA:3.40.50.300 5 197 2.0E-60 T 28-03-2018 ALX04_RS00835 9a5e5188346a6722ef0b56a65fa3451c 324 Gene3D G3DSA:3.30.360.10 146 324 4.9E-25 T 28-03-2018 ALX04_RS00835 9a5e5188346a6722ef0b56a65fa3451c 324 SUPERFAMILY SSF51735 2 154 2.68E-43 T 28-03-2018 IPR016040 NAD(P)-binding domain ALX04_RS00835 9a5e5188346a6722ef0b56a65fa3451c 324 Gene3D G3DSA:3.40.50.720 1 145 2.8E-37 T 28-03-2018 ALX04_RS00835 9a5e5188346a6722ef0b56a65fa3451c 324 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 6 120 2.6E-20 T 28-03-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 ALX04_RS00835 9a5e5188346a6722ef0b56a65fa3451c 324 SUPERFAMILY SSF55347 128 291 8.67E-32 T 28-03-2018 ALX04_RS15695 d3e2da3f6b039f615d45ecb57a69ae80 92 TIGRFAM TIGR01552 phd_fam: prevent-host-death family protein 5 50 7.3E-9 T 28-03-2018 ALX04_RS15695 d3e2da3f6b039f615d45ecb57a69ae80 92 Pfam PF02604 Antitoxin Phd_YefM, type II toxin-antitoxin system 8 54 2.1E-9 T 28-03-2018 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM ALX04_RS15695 d3e2da3f6b039f615d45ecb57a69ae80 92 Gene3D G3DSA:3.40.1620.10 3 40 1.8E-11 T 28-03-2018 ALX04_RS15695 d3e2da3f6b039f615d45ecb57a69ae80 92 SUPERFAMILY SSF143120 5 79 1.11E-11 T 28-03-2018 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM ALX04_RS02955 8651da32fa0793ed7f14992060ac9589 260 ProSitePatterns PS00614 Indole-3-glycerol phosphate synthase signature. 50 68 - T 28-03-2018 IPR001468 Indole-3-glycerol phosphate synthase, conserved site GO:0004425|GO:0006568 KEGG: 00400+4.1.1.48 ALX04_RS02955 8651da32fa0793ed7f14992060ac9589 260 Gene3D G3DSA:3.20.20.70 1 260 1.8E-69 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 ALX04_RS02955 8651da32fa0793ed7f14992060ac9589 260 SUPERFAMILY SSF51366 4 255 8.57E-74 T 28-03-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 ALX04_RS02955 8651da32fa0793ed7f14992060ac9589 260 Pfam PF00218 Indole-3-glycerol phosphate synthase 3 254 4.7E-85 T 28-03-2018 IPR013798 Indole-3-glycerol phosphate synthase GO:0004425 KEGG: 00400+4.1.1.48 ALX04_RS02955 8651da32fa0793ed7f14992060ac9589 260 Hamap MF_00134_B Indole-3-glycerol phosphate synthase [trpC]. 1 256 32.022 T 28-03-2018 IPR013798 Indole-3-glycerol phosphate synthase GO:0004425 KEGG: 00400+4.1.1.48 ALX04_RS13780 0402669fbe49682966097fc12aa5d1c8 389 Hamap MF_01107 Acetylornithine/succinyldiaminopimelate aminotransferase [argD]. 3 379 41.026 T 28-03-2018 IPR004636 Acetylornithine/Succinylornithine transaminase family GO:0006525|GO:0008483 ALX04_RS13780 0402669fbe49682966097fc12aa5d1c8 389 TIGRFAM TIGR00707 argD: transaminase, acetylornithine/succinylornithine family 6 378 1.1E-123 T 28-03-2018 IPR004636 Acetylornithine/Succinylornithine transaminase family GO:0006525|GO:0008483 ALX04_RS13780 0402669fbe49682966097fc12aa5d1c8 389 Gene3D G3DSA:3.90.1150.10 1 161 6.0E-45 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 ALX04_RS13780 0402669fbe49682966097fc12aa5d1c8 389 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 204 241 - T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 ALX04_RS13780 0402669fbe49682966097fc12aa5d1c8 389 Gene3D G3DSA:3.40.640.10 162 271 2.2E-35 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 ALX04_RS13780 0402669fbe49682966097fc12aa5d1c8 389 PIRSF PIRSF000521 3 115 3.8E-7 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 ALX04_RS13780 0402669fbe49682966097fc12aa5d1c8 389 PIRSF PIRSF000521 108 146 0.0033 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 ALX04_RS13780 0402669fbe49682966097fc12aa5d1c8 389 PIRSF PIRSF000521 153 381 1.9E-28 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 ALX04_RS13780 0402669fbe49682966097fc12aa5d1c8 389 Pfam PF00202 Aminotransferase class-III 11 378 6.8E-99 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 ALX04_RS13780 0402669fbe49682966097fc12aa5d1c8 389 Gene3D G3DSA:3.90.1150.10 272 389 7.4E-14 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 ALX04_RS13780 0402669fbe49682966097fc12aa5d1c8 389 SUPERFAMILY SSF53383 4 379 4.31E-108 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase ALX04_RS07285 d8572bf71ab7d69eaf5333c31ca07a6d 252 TIGRFAM TIGR00735 hisF: imidazoleglycerol phosphate synthase, cyclase subunit 1 252 2.3E-104 T 28-03-2018 IPR004651 Histidine biosynthesis, HisF GO:0000105|GO:0000107|GO:0005737 ALX04_RS07285 d8572bf71ab7d69eaf5333c31ca07a6d 252 Gene3D G3DSA:3.20.20.70 4 248 1.3E-61 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 ALX04_RS07285 d8572bf71ab7d69eaf5333c31ca07a6d 252 Pfam PF00977 Histidine biosynthesis protein 5 236 1.7E-82 T 28-03-2018 IPR006062 Histidine biosynthesis GO:0000105 ALX04_RS07285 d8572bf71ab7d69eaf5333c31ca07a6d 252 Hamap MF_01013 Imidazole glycerol phosphate synthase subunit HisF [hisF]. 1 252 46.606 T 28-03-2018 IPR004651 Histidine biosynthesis, HisF GO:0000105|GO:0000107|GO:0005737 ALX04_RS07285 d8572bf71ab7d69eaf5333c31ca07a6d 252 SUPERFAMILY SSF51366 1 252 5.65E-76 T 28-03-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 ALX04_RS04025 ea31f0f5167f5e05841ec4ef925b9dea 235 PIRSF PIRSF018637 4 233 2.6E-67 T 28-03-2018 IPR006901 tRNA methyltransferase TrmK GO:0016429 ALX04_RS04025 ea31f0f5167f5e05841ec4ef925b9dea 235 SUPERFAMILY SSF53335 16 142 3.13E-9 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase ALX04_RS04025 ea31f0f5167f5e05841ec4ef925b9dea 235 Pfam PF04816 tRNA (adenine(22)-N(1))-methyltransferase 23 211 6.7E-65 T 28-03-2018 IPR006901 tRNA methyltransferase TrmK GO:0016429 ALX04_RS04025 ea31f0f5167f5e05841ec4ef925b9dea 235 Gene3D G3DSA:3.40.50.150 1 167 6.1E-15 T 28-03-2018 ALX04_RS10080 a36ce2a8372df1aaf8cf696966008144 222 Gene3D G3DSA:1.10.340.30 27 126 1.5E-18 T 28-03-2018 ALX04_RS10080 a36ce2a8372df1aaf8cf696966008144 222 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 38 173 1.8E-10 T 28-03-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 ALX04_RS10080 a36ce2a8372df1aaf8cf696966008144 222 SUPERFAMILY SSF48150 3 200 2.09E-39 T 28-03-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 ALX04_RS10080 a36ce2a8372df1aaf8cf696966008144 222 Gene3D G3DSA:1.10.1670.10 127 207 1.1E-12 T 28-03-2018 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 ALX04_RS10080 a36ce2a8372df1aaf8cf696966008144 222 PIRSF PIRSF001435 1 214 2.1E-45 T 28-03-2018 ALX04_RS10080 a36ce2a8372df1aaf8cf696966008144 222 SMART SM00478 39 196 2.8E-16 T 28-03-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 ALX04_RS07440 471ce8e3ecde9a6674007628d99ed8db 256 ProSitePatterns PS01229 Hypothetical cof family signature 2. 204 226 - T 28-03-2018 ALX04_RS07440 471ce8e3ecde9a6674007628d99ed8db 256 TIGRFAM TIGR00099 Cof-subfamily: Cof-like hydrolase 6 249 8.7E-55 T 28-03-2018 IPR000150 Cof family GO:0016787 ALX04_RS07440 471ce8e3ecde9a6674007628d99ed8db 256 SUPERFAMILY SSF56784 4 253 1.07E-59 T 28-03-2018 IPR023214 HAD-like domain ALX04_RS07440 471ce8e3ecde9a6674007628d99ed8db 256 Pfam PF08282 haloacid dehalogenase-like hydrolase 7 249 4.8E-56 T 28-03-2018 IPR023214 HAD-like domain ALX04_RS07440 471ce8e3ecde9a6674007628d99ed8db 256 Gene3D G3DSA:3.40.50.1000 2 254 1.2E-41 T 28-03-2018 IPR023214 HAD-like domain ALX04_RS07440 471ce8e3ecde9a6674007628d99ed8db 256 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 5 223 1.0E-22 T 28-03-2018 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 ALX04_RS13530 aebbf15f6a90b61558e752ba479b8e68 258 Gene3D G3DSA:3.20.20.140 1 258 7.4E-85 T 28-03-2018 ALX04_RS13530 aebbf15f6a90b61558e752ba479b8e68 258 ProSitePatterns PS01137 TatD deoxyribonuclease family signature 1. 3 11 - T 28-03-2018 IPR018228 Deoxyribonuclease, TatD-related, conserved site GO:0016888 ALX04_RS13530 aebbf15f6a90b61558e752ba479b8e68 258 PIRSF PIRSF005902 1 258 9.1E-79 T 28-03-2018 IPR001130 TatD family GO:0016788 ALX04_RS13530 aebbf15f6a90b61558e752ba479b8e68 258 ProSitePatterns PS01090 TatD deoxyribonuclease family signature 2. 125 135 - T 28-03-2018 IPR018228 Deoxyribonuclease, TatD-related, conserved site GO:0016888 ALX04_RS13530 aebbf15f6a90b61558e752ba479b8e68 258 SUPERFAMILY SSF51556 1 255 1.19E-85 T 28-03-2018 IPR032466 Metal-dependent hydrolase ALX04_RS13530 aebbf15f6a90b61558e752ba479b8e68 258 Pfam PF01026 TatD related DNase 4 254 1.6E-78 T 28-03-2018 IPR001130 TatD family GO:0016788 ALX04_RS13530 aebbf15f6a90b61558e752ba479b8e68 258 TIGRFAM TIGR00010 TIGR00010: hydrolase, TatD family 3 254 1.6E-82 T 28-03-2018 IPR015991 Uncharacterised hydrolase TatD-type GO:0004536 ALX04_RS10110 d53e0ccb424768f21bcada3641e8ae41 118 Pfam PF08951 Enterocin A Immunity 34 85 1.1E-10 T 28-03-2018 IPR015046 Enterocin A Immunity ALX04_RS10110 d53e0ccb424768f21bcada3641e8ae41 118 SUPERFAMILY SSF109797 11 108 9.42E-35 T 28-03-2018 ALX04_RS03420 e104dd9cd649e0b486f080d4f09f25c6 98 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 52 67 3.2E-8 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 ALX04_RS03420 e104dd9cd649e0b486f080d4f09f25c6 98 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 67 82 3.2E-8 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 ALX04_RS03420 e104dd9cd649e0b486f080d4f09f25c6 98 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 18 33 3.2E-8 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 ALX04_RS03420 e104dd9cd649e0b486f080d4f09f25c6 98 SUPERFAMILY SSF46785 10 95 1.81E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS03420 e104dd9cd649e0b486f080d4f09f25c6 98 SMART SM00418 16 92 9.3E-11 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 ALX04_RS03420 e104dd9cd649e0b486f080d4f09f25c6 98 Pfam PF12840 Helix-turn-helix domain 17 74 6.9E-13 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS03420 e104dd9cd649e0b486f080d4f09f25c6 98 Gene3D G3DSA:1.10.10.10 8 96 2.3E-13 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS10465 82990d8293647f22dcc946af92ce27dd 366 Pfam PF01380 SIS domain 46 168 3.5E-8 T 28-03-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 ALX04_RS10465 82990d8293647f22dcc946af92ce27dd 366 Gene3D G3DSA:3.40.50.10490 210 356 5.3E-11 T 28-03-2018 ALX04_RS10465 82990d8293647f22dcc946af92ce27dd 366 SUPERFAMILY SSF53697 16 357 1.59E-32 T 28-03-2018 ALX04_RS10465 82990d8293647f22dcc946af92ce27dd 366 Gene3D G3DSA:3.40.50.10490 6 209 1.1E-15 T 28-03-2018 ALX04_RS11190 f8f94c01fa764cd496add936aa4a93a9 734 Gene3D G3DSA:1.50.10.10 299 658 5.4E-102 T 28-03-2018 ALX04_RS11190 f8f94c01fa764cd496add936aa4a93a9 734 SUPERFAMILY SSF74650 6 187 2.92E-27 T 28-03-2018 IPR011013 Galactose mutarotase-like domain GO:0003824|GO:0005975|GO:0030246 ALX04_RS11190 f8f94c01fa764cd496add936aa4a93a9 734 Gene3D G3DSA:2.60.420.10 659 729 4.9E-15 T 28-03-2018 ALX04_RS11190 f8f94c01fa764cd496add936aa4a93a9 734 Gene3D G3DSA:2.70.98.40 5 221 2.2E-27 T 28-03-2018 IPR005196 Glycoside hydrolase, family 65, N-terminal GO:0003824|GO:0005975 ALX04_RS11190 f8f94c01fa764cd496add936aa4a93a9 734 PIRSF PIRSF036289 1 734 7.4E-199 T 28-03-2018 IPR017045 Maltose phosphorylase/glycosyl hydrolase/vacuolar acid trehalase ALX04_RS11190 f8f94c01fa764cd496add936aa4a93a9 734 Pfam PF03636 Glycosyl hydrolase family 65, N-terminal domain 16 210 3.7E-20 T 28-03-2018 IPR005196 Glycoside hydrolase, family 65, N-terminal GO:0003824|GO:0005975 ALX04_RS11190 f8f94c01fa764cd496add936aa4a93a9 734 Pfam PF03632 Glycosyl hydrolase family 65 central catalytic domain 305 673 1.2E-104 T 28-03-2018 IPR005195 Glycoside hydrolase, family 65, central catalytic GO:0003824|GO:0005975 ALX04_RS11190 f8f94c01fa764cd496add936aa4a93a9 734 SUPERFAMILY SSF48208 273 726 2.38E-107 T 28-03-2018 IPR008928 Six-hairpin glycosidase-like GO:0003824 ALX04_RS11190 f8f94c01fa764cd496add936aa4a93a9 734 Pfam PF03633 Glycosyl hydrolase family 65, C-terminal domain 678 726 8.6E-11 T 28-03-2018 IPR005194 Glycoside hydrolase family 65, C-terminal ALX04_RS06890 cf5c065f2c5d029a7d43770ee097f935 89 TIGRFAM TIGR01560 put_DNA_pack: uncharacterized phage protein (possible DNA packaging) 5 86 1.4E-12 T 28-03-2018 IPR006450 Phage protein of unkonwn function ALX04_RS06890 cf5c065f2c5d029a7d43770ee097f935 89 Gene3D G3DSA:1.10.3230.10 1 81 0.0011 T 28-03-2018 ALX04_RS06890 cf5c065f2c5d029a7d43770ee097f935 89 Pfam PF05135 Phage gp6-like head-tail connector protein 3 84 1.1E-12 T 28-03-2018 IPR021146 Phage gp6-like head-tail connector protein ALX04_RS11510 a27b5e18980d4a6fb5a1296d37f4607d 438 PIRSF PIRSF005700 1 438 5.9E-173 T 28-03-2018 IPR004134 Peptidase C1B, bleomycin hydrolase GO:0004197|GO:0006508 Reactome: R-HSA-983168 ALX04_RS11510 a27b5e18980d4a6fb5a1296d37f4607d 438 SUPERFAMILY SSF54001 4 437 8.13E-128 T 28-03-2018 ALX04_RS11510 a27b5e18980d4a6fb5a1296d37f4607d 438 Pfam PF03051 Peptidase C1-like family 4 437 1.3E-174 T 28-03-2018 IPR004134 Peptidase C1B, bleomycin hydrolase GO:0004197|GO:0006508 Reactome: R-HSA-983168 ALX04_RS11510 a27b5e18980d4a6fb5a1296d37f4607d 438 Gene3D G3DSA:3.90.70.10 53 438 8.8E-113 T 28-03-2018 ALX04_RS11510 a27b5e18980d4a6fb5a1296d37f4607d 438 ProSitePatterns PS00639 Eukaryotic thiol (cysteine) proteases histidine active site. 360 370 - T 28-03-2018 IPR025660 Cysteine peptidase, histidine active site Reactome: R-HSA-2132295 ALX04_RS00790 c5479801887bbce5a7b160e9d527bbc2 895 Pfam PF12146 Serine aminopeptidase, S33 415 630 3.6E-9 T 28-03-2018 IPR022742 Serine aminopeptidase, S33 ALX04_RS00790 c5479801887bbce5a7b160e9d527bbc2 895 Gene3D G3DSA:3.40.50.1820 348 757 1.3E-26 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold ALX04_RS00790 c5479801887bbce5a7b160e9d527bbc2 895 TIGRFAM TIGR03715 KxYKxGKxW: KxYKxGKxW signal peptide 12 33 1.2E-9 T 28-03-2018 IPR022263 KxYKxGKxW signal peptide ALX04_RS00790 c5479801887bbce5a7b160e9d527bbc2 895 TIGRFAM TIGR01167 LPXTG_anchor: LPXTG cell wall anchor domain 860 893 4.6E-5 T 28-03-2018 ALX04_RS00790 c5479801887bbce5a7b160e9d527bbc2 895 SUPERFAMILY SSF53474 378 653 1.11E-27 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold ALX04_RS03535 622d872597779bfe687e5e9f8d617630 199 PIRSF PIRSF000709 1 147 8.3E-10 T 28-03-2018 ALX04_RS03535 622d872597779bfe687e5e9f8d617630 199 SUPERFAMILY SSF53254 3 189 5.24E-47 T 28-03-2018 IPR029033 Histidine phosphatase superfamily ALX04_RS03535 622d872597779bfe687e5e9f8d617630 199 ProSitePatterns PS00175 Phosphoglycerate mutase family phosphohistidine signature. 7 16 - T 28-03-2018 IPR001345 Phosphoglycerate/bisphosphoglycerate mutase, active site GO:0003824|GO:0008152 ALX04_RS03535 622d872597779bfe687e5e9f8d617630 199 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 5 190 1.2E-41 T 28-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 ALX04_RS03535 622d872597779bfe687e5e9f8d617630 199 Gene3D G3DSA:3.40.50.1240 1 198 2.1E-42 T 28-03-2018 IPR029033 Histidine phosphatase superfamily ALX04_RS03535 622d872597779bfe687e5e9f8d617630 199 SMART SM00855 4 153 4.3E-18 T 28-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 ALX04_RS14570 4dd7e50cc1952da4f13b483b161dec0d 294 Gene3D G3DSA:1.10.3720.10 55 290 1.2E-39 T 28-03-2018 ALX04_RS14570 4dd7e50cc1952da4f13b483b161dec0d 294 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 81 292 1.8E-37 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 ALX04_RS14570 4dd7e50cc1952da4f13b483b161dec0d 294 SUPERFAMILY SSF161098 15 278 4.67E-38 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 ALX04_RS14570 4dd7e50cc1952da4f13b483b161dec0d 294 TIGRFAM TIGR00974 3a0107s02c: phosphate ABC transporter, permease protein PstA 7 288 9.9E-81 T 28-03-2018 IPR005672 Phosphate transport system permease protein PstA GO:0005315|GO:0005887|GO:0035435 ALX04_RS15275 54f024240a44d9217cf142b538198291 309 Pfam PF03060 Nitronate monooxygenase 3 296 2.6E-72 T 28-03-2018 IPR004136 Nitronate monooxygenase GO:0018580|GO:0055114 KEGG: 00910+1.13.12.16|MetaCyc: PWY-723 ALX04_RS15275 54f024240a44d9217cf142b538198291 309 Gene3D G3DSA:3.20.20.70 1 309 5.9E-58 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 ALX04_RS15275 54f024240a44d9217cf142b538198291 309 SUPERFAMILY SSF51412 2 303 1.53E-68 T 28-03-2018 ALX04_RS00755 ba69aba08e09ee938c508d53796b093c 293 SUPERFAMILY SSF53850 89 290 3.94E-27 T 28-03-2018 ALX04_RS00755 ba69aba08e09ee938c508d53796b093c 293 Gene3D G3DSA:3.40.190.10 178 262 4.0E-14 T 28-03-2018 ALX04_RS00755 ba69aba08e09ee938c508d53796b093c 293 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 64 2.2E-13 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 ALX04_RS00755 ba69aba08e09ee938c508d53796b093c 293 Gene3D G3DSA:3.40.190.10 91 177 4.5E-12 T 28-03-2018 ALX04_RS00755 ba69aba08e09ee938c508d53796b093c 293 SUPERFAMILY SSF46785 1 108 2.86E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS00755 ba69aba08e09ee938c508d53796b093c 293 Gene3D G3DSA:1.10.10.10 1 90 7.7E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS00755 ba69aba08e09ee938c508d53796b093c 293 Pfam PF03466 LysR substrate binding domain 88 290 1.7E-28 T 28-03-2018 IPR005119 LysR, substrate-binding ALX04_RS07630 d7fb777218e7a81cae273917d88ab1e6 372 Gene3D G3DSA:2.20.28.20 3 29 1.2E-5 T 28-03-2018 ALX04_RS07630 d7fb777218e7a81cae273917d88ab1e6 372 Pfam PF13240 zinc-ribbon domain 4 25 7.6E-7 T 28-03-2018 IPR026870 Zinc-ribbon domain Reactome: R-HSA-202670 ALX04_RS04005 02d479f99c416115ba2286abef9c6105 66 Pfam PF11151 Protein of unknown function (DUF2929) 2 57 1.7E-22 T 28-03-2018 IPR021324 Protein of unknown function DUF2929 ALX04_RS00595 f7f64737f2d8d32d2dd86ea99dd1af67 670 TIGRFAM TIGR00232 tktlase_bact: transketolase 11 658 4.2E-247 T 28-03-2018 IPR005478 Transketolase, bacterial-like GO:0004802 KEGG: 00030+2.2.1.1|KEGG: 00710+2.2.1.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|MetaCyc: PWY-6901 ALX04_RS00595 f7f64737f2d8d32d2dd86ea99dd1af67 670 Gene3D G3DSA:3.40.50.970 2 351 8.4E-96 T 28-03-2018 ALX04_RS00595 f7f64737f2d8d32d2dd86ea99dd1af67 670 SUPERFAMILY SSF52518 347 521 3.67E-61 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold ALX04_RS00595 f7f64737f2d8d32d2dd86ea99dd1af67 670 SUPERFAMILY SSF52518 6 321 5.66E-100 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold ALX04_RS00595 f7f64737f2d8d32d2dd86ea99dd1af67 670 Pfam PF00456 Transketolase, thiamine diphosphate binding domain 8 324 2.1E-122 T 28-03-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 ALX04_RS00595 f7f64737f2d8d32d2dd86ea99dd1af67 670 Pfam PF02779 Transketolase, pyrimidine binding domain 355 519 3.6E-42 T 28-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain ALX04_RS00595 f7f64737f2d8d32d2dd86ea99dd1af67 670 SMART SM00861 349 520 2.9E-61 T 28-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain ALX04_RS00595 f7f64737f2d8d32d2dd86ea99dd1af67 670 SUPERFAMILY SSF52922 529 658 2.36E-31 T 28-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 ALX04_RS00595 f7f64737f2d8d32d2dd86ea99dd1af67 670 Pfam PF02780 Transketolase, C-terminal domain 550 650 8.1E-7 T 28-03-2018 IPR033248 Transketolase, C-terminal domain ALX04_RS00595 f7f64737f2d8d32d2dd86ea99dd1af67 670 Gene3D G3DSA:3.40.50.920 534 659 2.4E-25 T 28-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 ALX04_RS00595 f7f64737f2d8d32d2dd86ea99dd1af67 670 Gene3D G3DSA:3.40.50.970 352 531 4.3E-45 T 28-03-2018 ALX04_RS00595 f7f64737f2d8d32d2dd86ea99dd1af67 670 ProSitePatterns PS00801 Transketolase signature 1. 16 36 - T 28-03-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 ALX04_RS06220 5777c2e704bc400ecabe3269c9507f96 384 ProSitePatterns PS00595 Aminotransferases class-V pyridoxal-phosphate attachment site. 193 212 - T 28-03-2018 IPR020578 Aminotransferase class-V, pyridoxal-phosphate binding site ALX04_RS06220 5777c2e704bc400ecabe3269c9507f96 384 Pfam PF00266 Aminotransferase class-V 2 366 1.8E-70 T 28-03-2018 IPR000192 Aminotransferase class V domain ALX04_RS06220 5777c2e704bc400ecabe3269c9507f96 384 Gene3D G3DSA:3.90.1150.10 242 381 2.2E-29 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 ALX04_RS06220 5777c2e704bc400ecabe3269c9507f96 384 Gene3D G3DSA:3.40.640.10 10 241 5.8E-51 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 ALX04_RS06220 5777c2e704bc400ecabe3269c9507f96 384 SUPERFAMILY SSF53383 1 376 7.69E-96 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase ALX04_RS06220 5777c2e704bc400ecabe3269c9507f96 384 PIRSF PIRSF005572 1 381 1.7E-113 T 28-03-2018 IPR016454 Cysteine desulfurase KEGG: 00730+2.8.1.7|MetaCyc: PWY-6823|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7250 ALX04_RS09415 48d24cc6ed8031d1f42419d028fda12b 641 TIGRFAM TIGR01511 ATPase-IB1_Cu: copper-translocating P-type ATPase 49 629 2.3E-187 T 28-03-2018 ALX04_RS09415 48d24cc6ed8031d1f42419d028fda12b 641 SUPERFAMILY SSF81665 95 131 1.44E-17 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 ALX04_RS09415 48d24cc6ed8031d1f42419d028fda12b 641 SUPERFAMILY SSF81665 228 322 1.44E-17 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 ALX04_RS09415 48d24cc6ed8031d1f42419d028fda12b 641 SUPERFAMILY SSF81665 570 610 1.44E-17 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 ALX04_RS09415 48d24cc6ed8031d1f42419d028fda12b 641 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 67 629 6.8E-188 T 28-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 ALX04_RS09415 48d24cc6ed8031d1f42419d028fda12b 641 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 328 342 7.3E-27 T 28-03-2018 ALX04_RS09415 48d24cc6ed8031d1f42419d028fda12b 641 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 544 556 7.3E-27 T 28-03-2018 ALX04_RS09415 48d24cc6ed8031d1f42419d028fda12b 641 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 469 479 7.3E-27 T 28-03-2018 ALX04_RS09415 48d24cc6ed8031d1f42419d028fda12b 641 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 521 540 7.3E-27 T 28-03-2018 ALX04_RS09415 48d24cc6ed8031d1f42419d028fda12b 641 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 447 458 7.3E-27 T 28-03-2018 ALX04_RS09415 48d24cc6ed8031d1f42419d028fda12b 641 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 177 191 7.3E-27 T 28-03-2018 ALX04_RS09415 48d24cc6ed8031d1f42419d028fda12b 641 SUPERFAMILY SSF56784 381 626 1.26E-53 T 28-03-2018 IPR023214 HAD-like domain ALX04_RS09415 48d24cc6ed8031d1f42419d028fda12b 641 SUPERFAMILY SSF56784 326 346 1.26E-53 T 28-03-2018 IPR023214 HAD-like domain ALX04_RS09415 48d24cc6ed8031d1f42419d028fda12b 641 Gene3D G3DSA:1.20.1110.10 86 343 3.9E-46 T 28-03-2018 ALX04_RS09415 48d24cc6ed8031d1f42419d028fda12b 641 Pfam PF00702 haloacid dehalogenase-like hydrolase 324 535 2.5E-42 T 28-03-2018 ALX04_RS09415 48d24cc6ed8031d1f42419d028fda12b 641 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 330 336 - T 28-03-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 ALX04_RS09415 48d24cc6ed8031d1f42419d028fda12b 641 Gene3D G3DSA:3.40.50.1000 447 592 3.3E-36 T 28-03-2018 IPR023214 HAD-like domain ALX04_RS09415 48d24cc6ed8031d1f42419d028fda12b 641 SUPERFAMILY SSF81653 131 227 4.58E-29 T 28-03-2018 IPR008250 P-type ATPase, A domain Reactome: R-HSA-936837 ALX04_RS09415 48d24cc6ed8031d1f42419d028fda12b 641 PRINTS PR00943 Copper-transporting ATPase signature 555 569 1.7E-7 T 28-03-2018 ALX04_RS09415 48d24cc6ed8031d1f42419d028fda12b 641 PRINTS PR00943 Copper-transporting ATPase signature 499 516 1.7E-7 T 28-03-2018 ALX04_RS09415 48d24cc6ed8031d1f42419d028fda12b 641 PRINTS PR00943 Copper-transporting ATPase signature 97 116 1.7E-7 T 28-03-2018 ALX04_RS09415 48d24cc6ed8031d1f42419d028fda12b 641 PRINTS PR00943 Copper-transporting ATPase signature 311 326 1.7E-7 T 28-03-2018 ALX04_RS09415 48d24cc6ed8031d1f42419d028fda12b 641 PRINTS PR00943 Copper-transporting ATPase signature 594 608 1.7E-7 T 28-03-2018 ALX04_RS09415 48d24cc6ed8031d1f42419d028fda12b 641 PRINTS PR00943 Copper-transporting ATPase signature 250 264 1.7E-7 T 28-03-2018 ALX04_RS09415 48d24cc6ed8031d1f42419d028fda12b 641 ProSitePatterns PS01229 Hypothetical cof family signature 2. 521 543 - T 28-03-2018 ALX04_RS09415 48d24cc6ed8031d1f42419d028fda12b 641 Pfam PF00122 E1-E2 ATPase 128 307 1.2E-57 T 28-03-2018 ALX04_RS09415 48d24cc6ed8031d1f42419d028fda12b 641 Gene3D G3DSA:3.40.1110.10 344 446 1.2E-28 T 28-03-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 ALX04_RS09415 48d24cc6ed8031d1f42419d028fda12b 641 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 101 604 9.1E-92 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 ALX04_RS13615 2bdb87977bfcfd0966efc595f363cec5 146 Pfam PF09148 Domain of unknown function (DUF1934) 12 142 9.1E-30 T 28-03-2018 IPR015231 Protein of unknown function DUF1934 ALX04_RS13615 2bdb87977bfcfd0966efc595f363cec5 146 Gene3D G3DSA:2.40.128.20 1 146 3.7E-34 T 28-03-2018 IPR012674 Calycin ALX04_RS13615 2bdb87977bfcfd0966efc595f363cec5 146 SUPERFAMILY SSF50814 2 144 1.08E-36 T 28-03-2018 IPR012674 Calycin ALX04_RS00640 1bc3469f48882123aa19f3faf7f022e0 280 Hamap MF_00397 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase [citG]. 6 280 155.294 T 28-03-2018 IPR017551 Triphosphoribosyl-dephospho-CoA synthase CitG GO:0005524|GO:0016310|GO:0046917 MetaCyc: PWY-5796 ALX04_RS00640 1bc3469f48882123aa19f3faf7f022e0 280 TIGRFAM TIGR03125 citrate_citG: triphosphoribosyl-dephospho-CoA synthase CitG 6 272 2.5E-102 T 28-03-2018 IPR017551 Triphosphoribosyl-dephospho-CoA synthase CitG GO:0005524|GO:0016310|GO:0046917 MetaCyc: PWY-5796 ALX04_RS00640 1bc3469f48882123aa19f3faf7f022e0 280 Pfam PF01874 ATP:dephospho-CoA triphosphoribosyl transferase 9 272 2.5E-75 T 28-03-2018 IPR002736 Triphosphoribosyl-dephospho-CoA protein GO:0005524|GO:0016310|GO:0046917 MetaCyc: PWY-5796 ALX04_RS05105 7abd7ef7ab424ccaff1caea8ca1e2fd8 655 Pfam PF02302 PTS system, Lactose/Cellobiose specific IIB subunit 185 275 8.3E-16 T 28-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 ALX04_RS05105 7abd7ef7ab424ccaff1caea8ca1e2fd8 655 TIGRFAM TIGR00848 fruA: PTS system, fructose subfamily, IIA component 8 133 1.1E-38 T 28-03-2018 IPR004715 Phosphotransferase system, IIA component fructose subfamily GO:0008982|GO:0009401|GO:0016021 ALX04_RS05105 7abd7ef7ab424ccaff1caea8ca1e2fd8 655 Gene3D G3DSA:3.40.50.2300 182 278 2.9E-34 T 28-03-2018 ALX04_RS05105 7abd7ef7ab424ccaff1caea8ca1e2fd8 655 ProSitePatterns PS00372 PTS EIIA domains phosphorylation site signature 2. 52 68 - T 28-03-2018 IPR002178 PTS EIIA type-2 domain ALX04_RS05105 7abd7ef7ab424ccaff1caea8ca1e2fd8 655 TIGRFAM TIGR00829 FRU: PTS system, Fru family, IIB component 184 266 1.3E-25 T 28-03-2018 IPR003353 Phosphotransferase system, fructose-specific IIB subunit GO:0009401|GO:0022877 KEGG: 00051+2.7.1.202|KEGG: 00230+2.7.1.20|MetaCyc: PWY-6619 ALX04_RS05105 7abd7ef7ab424ccaff1caea8ca1e2fd8 655 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 7 146 1.2E-38 T 28-03-2018 IPR002178 PTS EIIA type-2 domain ALX04_RS05105 7abd7ef7ab424ccaff1caea8ca1e2fd8 655 SUPERFAMILY SSF55804 1 147 5.23E-44 T 28-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 ALX04_RS05105 7abd7ef7ab424ccaff1caea8ca1e2fd8 655 Gene3D G3DSA:3.40.930.10 1 162 3.3E-43 T 28-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 ALX04_RS05105 7abd7ef7ab424ccaff1caea8ca1e2fd8 655 TIGRFAM TIGR01427 PTS_IIC_fructo: PTS system, Fru family, IIC component 307 649 1.5E-103 T 28-03-2018 IPR006327 Phosphotransferase system, fructose IIC component GO:0005351|GO:0008982|GO:0009401|GO:0016021 ALX04_RS05105 7abd7ef7ab424ccaff1caea8ca1e2fd8 655 SUPERFAMILY SSF52794 183 284 1.74E-33 T 28-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 ALX04_RS05105 7abd7ef7ab424ccaff1caea8ca1e2fd8 655 Pfam PF02378 Phosphotransferase system, EIIC 314 586 1.5E-21 T 28-03-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 ALX04_RS10015 03b74b1395706093106320f8804a26c8 481 TIGRFAM TIGR00479 rumA: 23S rRNA (uracil-5-)-methyltransferase RumA 43 472 2.4E-132 T 28-03-2018 IPR001566 23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD GO:0003723|GO:0006396|GO:0008173 ALX04_RS10015 03b74b1395706093106320f8804a26c8 481 Gene3D G3DSA:3.40.50.150 228 478 1.2E-37 T 28-03-2018 ALX04_RS10015 03b74b1395706093106320f8804a26c8 481 Gene3D G3DSA:3.40.50.150 102 195 1.1E-6 T 28-03-2018 ALX04_RS10015 03b74b1395706093106320f8804a26c8 481 Gene3D G3DSA:2.40.50.140 19 101 9.6E-18 T 28-03-2018 ALX04_RS10015 03b74b1395706093106320f8804a26c8 481 Pfam PF01938 TRAM domain 32 84 1.7E-8 T 28-03-2018 IPR002792 TRAM domain ALX04_RS10015 03b74b1395706093106320f8804a26c8 481 Pfam PF05958 tRNA (Uracil-5-)-methyltransferase 303 479 3.8E-18 T 28-03-2018 IPR010280 (Uracil-5)-methyltransferase family GO:0006396|GO:0008173 ALX04_RS10015 03b74b1395706093106320f8804a26c8 481 SUPERFAMILY SSF50249 25 85 1.31E-13 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold ALX04_RS10015 03b74b1395706093106320f8804a26c8 481 ProSitePatterns PS01230 RNA methyltransferase trmA family signature 1. 411 442 - T 28-03-2018 IPR030390 RNA methyltransferase TrmA, active site ALX04_RS10015 03b74b1395706093106320f8804a26c8 481 SUPERFAMILY SSF53335 94 479 8.36E-71 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase ALX04_RS09975 a18a05b67857d7355e64fcee2bee7a8d 311 Pfam PF13349 Putative adhesin 53 308 2.0E-52 T 28-03-2018 IPR025164 Putative adhesin ALX04_RS09975 a18a05b67857d7355e64fcee2bee7a8d 311 Gene3D G3DSA:2.160.20.20 26 311 9.8E-5 T 28-03-2018 IPR012332 P22 tailspike C-terminal domain-like ALX04_RS10450 f54c935ab80cabec936a3cd869d75944 222 Pfam PF04237 YjbR 120 220 1.6E-8 T 28-03-2018 IPR007351 Uncharacterised protein YjbR ALX04_RS10450 f54c935ab80cabec936a3cd869d75944 222 SUPERFAMILY SSF142906 104 221 4.84E-23 T 28-03-2018 ALX04_RS09850 da79185a9fb233c8fa519f4f3b01f5c4 444 Pfam PF00768 D-alanyl-D-alanine carboxypeptidase 35 293 2.7E-61 T 28-03-2018 IPR001967 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A, N-terminal GO:0006508|GO:0009002 ALX04_RS09850 da79185a9fb233c8fa519f4f3b01f5c4 444 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 70 81 1.8E-8 T 28-03-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 ALX04_RS09850 da79185a9fb233c8fa519f4f3b01f5c4 444 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 154 167 1.8E-8 T 28-03-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 ALX04_RS09850 da79185a9fb233c8fa519f4f3b01f5c4 444 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 127 144 1.8E-8 T 28-03-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 ALX04_RS09850 da79185a9fb233c8fa519f4f3b01f5c4 444 Gene3D G3DSA:3.40.710.10 31 318 8.3E-44 T 28-03-2018 ALX04_RS09850 da79185a9fb233c8fa519f4f3b01f5c4 444 SUPERFAMILY SSF56601 10 318 3.76E-59 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like ALX04_RS09850 da79185a9fb233c8fa519f4f3b01f5c4 444 SUPERFAMILY SSF69189 310 437 7.26E-8 T 28-03-2018 IPR015956 Penicillin-binding protein-associated GO:0004180|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 ALX04_RS09850 da79185a9fb233c8fa519f4f3b01f5c4 444 SMART SM00936 318 428 2.2E-5 T 28-03-2018 IPR012907 Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 ALX04_RS09850 da79185a9fb233c8fa519f4f3b01f5c4 444 Gene3D G3DSA:2.60.410.10 319 425 7.9E-9 T 28-03-2018 IPR012907 Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 ALX04_RS05950 a464edddc62566f3dd71bac5bd6b4ade 384 SUPERFAMILY SSF53187 6 195 2.48E-59 T 28-03-2018 ALX04_RS05950 a464edddc62566f3dd71bac5bd6b4ade 384 SUPERFAMILY SSF53187 297 376 2.48E-59 T 28-03-2018 ALX04_RS05950 a464edddc62566f3dd71bac5bd6b4ade 384 PIRSF PIRSF005962 3 384 2.8E-95 T 28-03-2018 IPR017439 Amidohydrolase GO:0016787 ALX04_RS05950 a464edddc62566f3dd71bac5bd6b4ade 384 Hamap MF_01692 N-acetyldiaminopimelate deacetylase. 5 379 63.127 T 28-03-2018 IPR023905 Acetyldiaminopimelate deacetylase GO:0009089|GO:0050118 KEGG: 00300+3.5.1.47|MetaCyc: PWY-2941 ALX04_RS05950 a464edddc62566f3dd71bac5bd6b4ade 384 Pfam PF01546 Peptidase family M20/M25/M40 72 376 5.5E-24 T 28-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 ALX04_RS05950 a464edddc62566f3dd71bac5bd6b4ade 384 Gene3D G3DSA:3.40.630.10 3 243 4.5E-32 T 28-03-2018 ALX04_RS05950 a464edddc62566f3dd71bac5bd6b4ade 384 Gene3D G3DSA:3.40.630.10 244 379 8.3E-16 T 28-03-2018 ALX04_RS05950 a464edddc62566f3dd71bac5bd6b4ade 384 TIGRFAM TIGR01891 amidohydrolases: amidohydrolase 9 358 6.4E-83 T 28-03-2018 IPR017439 Amidohydrolase GO:0016787 ALX04_RS05950 a464edddc62566f3dd71bac5bd6b4ade 384 SUPERFAMILY SSF55031 180 288 3.01E-26 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain ALX04_RS05950 a464edddc62566f3dd71bac5bd6b4ade 384 Pfam PF07687 Peptidase dimerisation domain 181 278 9.6E-5 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain ALX04_RS02315 aea9d4ff77b227331637c68a673542e6 197 SUPERFAMILY SSF52540 1 195 2.44E-37 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase ALX04_RS02315 aea9d4ff77b227331637c68a673542e6 197 Hamap MF_00376 Dephospho-CoA kinase [coaE]. 2 194 23.696 T 28-03-2018 IPR001977 Dephospho-CoA kinase GO:0004140|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.24|MetaCyc: PWY-7851 ALX04_RS02315 aea9d4ff77b227331637c68a673542e6 197 Pfam PF01121 Dephospho-CoA kinase 4 181 3.1E-53 T 28-03-2018 IPR001977 Dephospho-CoA kinase GO:0004140|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.24|MetaCyc: PWY-7851 ALX04_RS02315 aea9d4ff77b227331637c68a673542e6 197 Gene3D G3DSA:3.40.50.300 2 197 6.1E-42 T 28-03-2018 ALX04_RS02315 aea9d4ff77b227331637c68a673542e6 197 TIGRFAM TIGR00152 TIGR00152: dephospho-CoA kinase 4 188 5.1E-55 T 28-03-2018 IPR001977 Dephospho-CoA kinase GO:0004140|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.24|MetaCyc: PWY-7851 ALX04_RS04000 9d76ae8de86cf2f16ddbb2f5611f226d 1116 SMART SM00481 5 72 7.6E-14 T 28-03-2018 IPR003141 Polymerase/histidinol phosphatase, N-terminal ALX04_RS04000 9d76ae8de86cf2f16ddbb2f5611f226d 1116 TIGRFAM TIGR00594 polc: DNA polymerase III, alpha subunit 4 992 0.0 T 28-03-2018 IPR004805 DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 ALX04_RS04000 9d76ae8de86cf2f16ddbb2f5611f226d 1116 Gene3D G3DSA:3.20.20.140 3 234 1.2E-23 T 28-03-2018 ALX04_RS04000 9d76ae8de86cf2f16ddbb2f5611f226d 1116 Pfam PF07733 Bacterial DNA polymerase III alpha subunit 286 713 3.0E-167 T 28-03-2018 IPR011708 Bacterial DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 ALX04_RS04000 9d76ae8de86cf2f16ddbb2f5611f226d 1116 SUPERFAMILY SSF89550 11 72 6.87E-8 T 28-03-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 ALX04_RS04000 9d76ae8de86cf2f16ddbb2f5611f226d 1116 Pfam PF02811 PHP domain 9 151 1.6E-24 T 28-03-2018 IPR004013 PHP domain GO:0003824 ALX04_RS04000 9d76ae8de86cf2f16ddbb2f5611f226d 1116 Pfam PF01336 OB-fold nucleic acid binding domain 964 1030 1.9E-7 T 28-03-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 ALX04_RS04000 9d76ae8de86cf2f16ddbb2f5611f226d 1116 Gene3D G3DSA:1.10.150.280 774 871 4.0E-4 T 28-03-2018 ALX04_RS04000 9d76ae8de86cf2f16ddbb2f5611f226d 1116 Pfam PF14579 Helix-hairpin-helix motif 787 875 1.7E-23 T 28-03-2018 IPR029460 DNA polymerase, helix-hairpin-helix motif KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 ALX04_RS04000 9d76ae8de86cf2f16ddbb2f5611f226d 1116 Gene3D G3DSA:2.40.50.140 937 1030 4.5E-12 T 28-03-2018 ALX04_RS14520 a96d6b951131c3e2095a42a81210bd12 450 Gene3D G3DSA:3.40.50.300 276 443 4.5E-17 T 28-03-2018 ALX04_RS14520 a96d6b951131c3e2095a42a81210bd12 450 SMART SM00490 323 402 1.0E-5 T 28-03-2018 IPR001650 Helicase, C-terminal ALX04_RS14520 a96d6b951131c3e2095a42a81210bd12 450 Pfam PF00271 Helicase conserved C-terminal domain 294 401 1.0E-10 T 28-03-2018 IPR001650 Helicase, C-terminal ALX04_RS14520 a96d6b951131c3e2095a42a81210bd12 450 SUPERFAMILY SSF52540 114 415 1.75E-32 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase ALX04_RS14520 a96d6b951131c3e2095a42a81210bd12 450 SMART SM00487 93 268 2.1E-14 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain ALX04_RS14520 a96d6b951131c3e2095a42a81210bd12 450 Gene3D G3DSA:3.40.50.300 92 261 2.4E-18 T 28-03-2018 ALX04_RS07755 45fb7ca0a4802943a94986beff40e227 390 SUPERFAMILY SSF53383 1 379 8.78E-107 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase ALX04_RS07755 45fb7ca0a4802943a94986beff40e227 390 Gene3D G3DSA:3.40.640.10 41 270 3.8E-48 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 ALX04_RS07755 45fb7ca0a4802943a94986beff40e227 390 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 230 243 - T 28-03-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 ALX04_RS07755 45fb7ca0a4802943a94986beff40e227 390 PRINTS PR00753 1-aminocyclopropane-1-carboxylate synthase signature 111 132 2.4E-11 T 28-03-2018 ALX04_RS07755 45fb7ca0a4802943a94986beff40e227 390 PRINTS PR00753 1-aminocyclopropane-1-carboxylate synthase signature 161 185 2.4E-11 T 28-03-2018 ALX04_RS07755 45fb7ca0a4802943a94986beff40e227 390 PRINTS PR00753 1-aminocyclopropane-1-carboxylate synthase signature 197 220 2.4E-11 T 28-03-2018 ALX04_RS07755 45fb7ca0a4802943a94986beff40e227 390 PRINTS PR00753 1-aminocyclopropane-1-carboxylate synthase signature 89 109 2.4E-11 T 28-03-2018 ALX04_RS07755 45fb7ca0a4802943a94986beff40e227 390 Gene3D G3DSA:3.90.1150.10 271 386 8.4E-31 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 ALX04_RS07755 45fb7ca0a4802943a94986beff40e227 390 Pfam PF00155 Aminotransferase class I and II 28 377 2.1E-67 T 28-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 ALX04_RS14610 c7987f117ea1aeee1552027d47f3abac 338 PIRSF PIRSF000114 1 337 1.3E-105 T 28-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 ALX04_RS14610 c7987f117ea1aeee1552027d47f3abac 338 Pfam PF01210 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 4 165 6.5E-55 T 28-03-2018 IPR011128 Glycerol-3-phosphate dehydrogenase, NAD-dependent, N-terminal GO:0016616|GO:0046168|GO:0051287|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 ALX04_RS14610 c7987f117ea1aeee1552027d47f3abac 338 SUPERFAMILY SSF48179 184 336 8.67E-54 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 ALX04_RS14610 c7987f117ea1aeee1552027d47f3abac 338 Gene3D G3DSA:3.40.50.720 2 184 3.2E-39 T 28-03-2018 ALX04_RS14610 c7987f117ea1aeee1552027d47f3abac 338 Pfam PF07479 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus 185 325 8.9E-52 T 28-03-2018 IPR006109 Glycerol-3-phosphate dehydrogenase, NAD-dependent, C-terminal GO:0004367|GO:0005975|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 ALX04_RS14610 c7987f117ea1aeee1552027d47f3abac 338 Hamap MF_00394 Glycerol-3-phosphate dehydrogenase [NAD(P)+] [gpsA]. 3 327 36.466 T 28-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 ALX04_RS14610 c7987f117ea1aeee1552027d47f3abac 338 ProSitePatterns PS00957 NAD-dependent glycerol-3-phosphate dehydrogenase signature. 193 214 - T 28-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 ALX04_RS14610 c7987f117ea1aeee1552027d47f3abac 338 SUPERFAMILY SSF51735 4 184 5.34E-58 T 28-03-2018 IPR016040 NAD(P)-binding domain ALX04_RS14610 c7987f117ea1aeee1552027d47f3abac 338 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 138 158 5.4E-44 T 28-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 ALX04_RS14610 c7987f117ea1aeee1552027d47f3abac 338 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 7 24 5.4E-44 T 28-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 ALX04_RS14610 c7987f117ea1aeee1552027d47f3abac 338 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 203 227 5.4E-44 T 28-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 ALX04_RS14610 c7987f117ea1aeee1552027d47f3abac 338 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 178 202 5.4E-44 T 28-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 ALX04_RS14610 c7987f117ea1aeee1552027d47f3abac 338 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 243 260 5.4E-44 T 28-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 ALX04_RS14610 c7987f117ea1aeee1552027d47f3abac 338 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 57 84 5.4E-44 T 28-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 ALX04_RS14610 c7987f117ea1aeee1552027d47f3abac 338 Gene3D G3DSA:1.10.1040.10 185 335 1.9E-52 T 28-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 ALX04_RS00025 a11186afae6125d00343ded2a33e85ef 183 Pfam PF08951 Enterocin A Immunity 105 174 1.6E-13 T 28-03-2018 IPR015046 Enterocin A Immunity ALX04_RS00025 a11186afae6125d00343ded2a33e85ef 183 Pfam PF01381 Helix-turn-helix 9 63 1.1E-16 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 ALX04_RS00025 a11186afae6125d00343ded2a33e85ef 183 SUPERFAMILY SSF47413 2 67 1.71E-18 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 ALX04_RS00025 a11186afae6125d00343ded2a33e85ef 183 Gene3D G3DSA:1.10.260.40 2 72 1.2E-19 T 28-03-2018 ALX04_RS00025 a11186afae6125d00343ded2a33e85ef 183 SMART SM00530 8 63 6.1E-16 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 ALX04_RS00025 a11186afae6125d00343ded2a33e85ef 183 Gene3D G3DSA:1.20.1440.50 106 179 3.1E-5 T 28-03-2018 IPR023130 Ta0600-like domain ALX04_RS10150 8a3be9a1f6302d856436ae556ae39aef 232 Pfam PF04298 Putative neutral zinc metallopeptidase 9 225 2.9E-86 T 28-03-2018 IPR007395 Putative neutral zinc metallopeptidase ALX04_RS11530 cc957b0d437eb68a4c3bf5bcac338944 353 Pfam PF11797 Protein of unknown function C-terminal (DUF3324) 175 310 6.3E-41 T 28-03-2018 IPR021759 Domain of unknown function DUF3324, C-terminal ALX04_RS11530 cc957b0d437eb68a4c3bf5bcac338944 353 Gene3D G3DSA:2.60.40.1710 52 181 6.4E-8 T 28-03-2018 ALX04_RS11530 cc957b0d437eb68a4c3bf5bcac338944 353 Pfam PF06030 Bacterial protein of unknown function (DUF916) 43 163 2.0E-40 T 28-03-2018 IPR010317 Protein of unknown function DUF916, cell surface putative ALX04_RS11530 cc957b0d437eb68a4c3bf5bcac338944 353 Gene3D G3DSA:1.20.5.900 318 353 8.9E-4 T 28-03-2018 ALX04_RS09950 107781102fad51a8388334c2fd4ab73a 253 SUPERFAMILY SSF52540 1 236 3.3E-71 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase ALX04_RS09950 107781102fad51a8388334c2fd4ab73a 253 Gene3D G3DSA:3.40.50.300 1 252 5.1E-70 T 28-03-2018 ALX04_RS09950 107781102fad51a8388334c2fd4ab73a 253 Pfam PF00005 ABC transporter 17 169 6.5E-32 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 ALX04_RS09950 107781102fad51a8388334c2fd4ab73a 253 ProSitePatterns PS00211 ABC transporters family signature. 141 155 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 ALX04_RS09950 107781102fad51a8388334c2fd4ab73a 253 PIRSF PIRSF039085 1 244 6.3E-95 T 28-03-2018 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 ALX04_RS09950 107781102fad51a8388334c2fd4ab73a 253 SMART SM00382 26 217 1.3E-13 T 28-03-2018 IPR003593 AAA+ ATPase domain ALX04_RS12325 9297fd28bbc75f66c32e3270b8416f46 294 SUPERFAMILY SSF161098 21 294 1.01E-60 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 ALX04_RS12325 9297fd28bbc75f66c32e3270b8416f46 294 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 113 285 1.5E-21 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 ALX04_RS12325 9297fd28bbc75f66c32e3270b8416f46 294 Gene3D G3DSA:1.10.3720.10 15 281 2.5E-37 T 28-03-2018 ALX04_RS14705 c9da781fddcf229be1aeff389b7e1b1c 294 Hamap MF_00636 RNase adapter protein RapZ [rapZ]. 5 286 42.246 T 28-03-2018 IPR005337 RapZ-like family GO:0005524 ALX04_RS14705 c9da781fddcf229be1aeff389b7e1b1c 294 SUPERFAMILY SSF52540 7 159 1.27E-15 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase ALX04_RS14705 c9da781fddcf229be1aeff389b7e1b1c 294 Pfam PF03668 P-loop ATPase protein family 5 287 6.8E-112 T 28-03-2018 IPR005337 RapZ-like family GO:0005524 ALX04_RS14705 c9da781fddcf229be1aeff389b7e1b1c 294 Gene3D G3DSA:3.40.50.300 4 164 2.9E-11 T 28-03-2018 ALX04_RS14705 c9da781fddcf229be1aeff389b7e1b1c 294 PIRSF PIRSF005052 5 289 1.9E-111 T 28-03-2018 IPR005337 RapZ-like family GO:0005524 ALX04_RS01425 326ddd6ac266229c1fa52191a2f61971 340 Pfam PF00534 Glycosyl transferases group 1 154 303 3.1E-18 T 28-03-2018 IPR001296 Glycosyl transferase, family 1 ALX04_RS01425 326ddd6ac266229c1fa52191a2f61971 340 Gene3D G3DSA:3.40.50.2000 152 319 4.0E-31 T 28-03-2018 ALX04_RS01425 326ddd6ac266229c1fa52191a2f61971 340 SUPERFAMILY SSF53756 17 333 9.87E-49 T 28-03-2018 ALX04_RS01425 326ddd6ac266229c1fa52191a2f61971 340 Gene3D G3DSA:3.40.50.2000 12 151 5.3E-4 T 28-03-2018 ALX04_RS01650 95baf2f881ca7d2a19d7f159700bf203 808 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 417 607 1.1E-20 T 28-03-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 ALX04_RS01650 95baf2f881ca7d2a19d7f159700bf203 808 Gene3D G3DSA:3.90.740.10 230 403 4.0E-56 T 28-03-2018 ALX04_RS01650 95baf2f881ca7d2a19d7f159700bf203 808 TIGRFAM TIGR00396 leuS_bact: leucine--tRNA ligase 3 575 3.0E-269 T 28-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 ALX04_RS01650 95baf2f881ca7d2a19d7f159700bf203 808 Hamap MF_00049_B Leucine--tRNA ligase [leuS]. 2 807 22.502 T 28-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 ALX04_RS01650 95baf2f881ca7d2a19d7f159700bf203 808 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 42 52 - T 28-03-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 ALX04_RS01650 95baf2f881ca7d2a19d7f159700bf203 808 SUPERFAMILY SSF50677 226 415 1.15E-52 T 28-03-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 ALX04_RS01650 95baf2f881ca7d2a19d7f159700bf203 808 SUPERFAMILY SSF52374 416 628 1.28E-137 T 28-03-2018 ALX04_RS01650 95baf2f881ca7d2a19d7f159700bf203 808 SUPERFAMILY SSF52374 1 226 1.28E-137 T 28-03-2018 ALX04_RS01650 95baf2f881ca7d2a19d7f159700bf203 808 PRINTS PR00985 Leucyl-tRNA synthetase signature 186 199 3.9E-47 T 28-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 ALX04_RS01650 95baf2f881ca7d2a19d7f159700bf203 808 PRINTS PR00985 Leucyl-tRNA synthetase signature 215 234 3.9E-47 T 28-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 ALX04_RS01650 95baf2f881ca7d2a19d7f159700bf203 808 PRINTS PR00985 Leucyl-tRNA synthetase signature 489 507 3.9E-47 T 28-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 ALX04_RS01650 95baf2f881ca7d2a19d7f159700bf203 808 PRINTS PR00985 Leucyl-tRNA synthetase signature 126 143 3.9E-47 T 28-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 ALX04_RS01650 95baf2f881ca7d2a19d7f159700bf203 808 PRINTS PR00985 Leucyl-tRNA synthetase signature 561 571 3.9E-47 T 28-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 ALX04_RS01650 95baf2f881ca7d2a19d7f159700bf203 808 PRINTS PR00985 Leucyl-tRNA synthetase signature 528 550 3.9E-47 T 28-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 ALX04_RS01650 95baf2f881ca7d2a19d7f159700bf203 808 Pfam PF08264 Anticodon-binding domain of tRNA 659 767 1.9E-18 T 28-03-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0000166|GO:0006418 ALX04_RS01650 95baf2f881ca7d2a19d7f159700bf203 808 Pfam PF13603 Leucyl-tRNA synthetase, Domain 2 221 403 3.5E-67 T 28-03-2018 IPR025709 Leucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 KEGG: 00970+6.1.1.4 ALX04_RS01650 95baf2f881ca7d2a19d7f159700bf203 808 Gene3D G3DSA:3.40.50.620 1 229 2.4E-71 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold ALX04_RS01650 95baf2f881ca7d2a19d7f159700bf203 808 Pfam PF09334 tRNA synthetases class I (M) 39 155 1.9E-17 T 28-03-2018 IPR015413 Methionyl/Leucyl tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0006418 ALX04_RS01650 95baf2f881ca7d2a19d7f159700bf203 808 Gene3D G3DSA:1.10.730.10 609 744 9.2E-29 T 28-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 ALX04_RS01650 95baf2f881ca7d2a19d7f159700bf203 808 Gene3D G3DSA:3.40.50.620 404 608 2.6E-71 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold ALX04_RS01650 95baf2f881ca7d2a19d7f159700bf203 808 SUPERFAMILY SSF47323 623 807 6.73E-39 T 28-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 ALX04_RS00150 dc41b99e3a16faed18ba8e179a581b7c 633 TIGRFAM TIGR01536 asn_synth_AEB: asparagine synthase (glutamine-hydrolyzing) 2 546 3.3E-163 T 28-03-2018 IPR006426 Asparagine synthase, glutamine-hydrolyzing GO:0004066|GO:0006529 KEGG: 00250+6.3.5.4|Reactome: R-HSA-380994|Reactome: R-HSA-70614 ALX04_RS00150 dc41b99e3a16faed18ba8e179a581b7c 633 SUPERFAMILY SSF52402 228 380 7.39E-88 T 28-03-2018 ALX04_RS00150 dc41b99e3a16faed18ba8e179a581b7c 633 SUPERFAMILY SSF52402 466 604 7.39E-88 T 28-03-2018 ALX04_RS00150 dc41b99e3a16faed18ba8e179a581b7c 633 Gene3D G3DSA:3.60.20.10 1 222 7.3E-53 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal ALX04_RS00150 dc41b99e3a16faed18ba8e179a581b7c 633 Pfam PF00733 Asparagine synthase 240 609 3.0E-106 T 28-03-2018 IPR001962 Asparagine synthase GO:0004066|GO:0006529 ALX04_RS00150 dc41b99e3a16faed18ba8e179a581b7c 633 Gene3D G3DSA:3.40.50.620 223 616 8.0E-81 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold ALX04_RS00150 dc41b99e3a16faed18ba8e179a581b7c 633 PIRSF PIRSF001589 1 630 6.5E-236 T 28-03-2018 IPR006426 Asparagine synthase, glutamine-hydrolyzing GO:0004066|GO:0006529 KEGG: 00250+6.3.5.4|Reactome: R-HSA-380994|Reactome: R-HSA-70614 ALX04_RS00150 dc41b99e3a16faed18ba8e179a581b7c 633 Pfam PF13537 Glutamine amidotransferase domain 51 167 3.4E-45 T 28-03-2018 IPR017932 Glutamine amidotransferase type 2 domain ALX04_RS00150 dc41b99e3a16faed18ba8e179a581b7c 633 SUPERFAMILY SSF56235 1 222 3.0E-61 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal ALX04_RS14475 02a58a6a8e1709aaaf4dfd30406c562d 660 Pfam PF12848 ABC transporter 235 318 1.1E-25 T 28-03-2018 IPR032781 ABC-transporter extension domain ALX04_RS14475 02a58a6a8e1709aaaf4dfd30406c562d 660 SUPERFAMILY SSF52540 4 249 3.14E-45 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase ALX04_RS14475 02a58a6a8e1709aaaf4dfd30406c562d 660 Gene3D G3DSA:3.40.50.300 4 294 7.4E-53 T 28-03-2018 ALX04_RS14475 02a58a6a8e1709aaaf4dfd30406c562d 660 Gene3D G3DSA:3.40.50.300 295 557 1.4E-47 T 28-03-2018 ALX04_RS14475 02a58a6a8e1709aaaf4dfd30406c562d 660 SUPERFAMILY SSF52540 309 533 8.01E-42 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase ALX04_RS14475 02a58a6a8e1709aaaf4dfd30406c562d 660 SMART SM00382 28 247 2.0E-10 T 28-03-2018 IPR003593 AAA+ ATPase domain ALX04_RS14475 02a58a6a8e1709aaaf4dfd30406c562d 660 SMART SM00382 355 521 2.9E-12 T 28-03-2018 IPR003593 AAA+ ATPase domain ALX04_RS14475 02a58a6a8e1709aaaf4dfd30406c562d 660 Pfam PF16326 ABC transporter C-terminal domain 585 651 1.3E-9 T 28-03-2018 IPR032524 ABC transporter Uup, C-terminal GO:0003677 ALX04_RS14475 02a58a6a8e1709aaaf4dfd30406c562d 660 Pfam PF00005 ABC transporter 20 195 1.6E-28 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 ALX04_RS14475 02a58a6a8e1709aaaf4dfd30406c562d 660 Pfam PF00005 ABC transporter 350 476 3.3E-18 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 ALX04_RS14475 02a58a6a8e1709aaaf4dfd30406c562d 660 Gene3D G3DSA:1.20.58.410 580 660 0.0059 T 28-03-2018 ALX04_RS04055 4f2fe3fdd77214a5255d9737754587ff 122 Pfam PF00581 Rhodanese-like domain 23 111 8.7E-9 T 28-03-2018 IPR001763 Rhodanese-like domain ALX04_RS04055 4f2fe3fdd77214a5255d9737754587ff 122 SMART SM00450 19 116 1.5E-9 T 28-03-2018 IPR001763 Rhodanese-like domain ALX04_RS04055 4f2fe3fdd77214a5255d9737754587ff 122 Gene3D G3DSA:3.40.250.10 1 121 7.3E-20 T 28-03-2018 IPR001763 Rhodanese-like domain ALX04_RS04055 4f2fe3fdd77214a5255d9737754587ff 122 SUPERFAMILY SSF52821 23 118 9.82E-18 T 28-03-2018 IPR001763 Rhodanese-like domain ALX04_RS12620 3ebc8b2fb1397a1fab413af92581c93d 231 Pfam PF07702 UTRA domain 91 220 1.5E-20 T 28-03-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 ALX04_RS12620 3ebc8b2fb1397a1fab413af92581c93d 231 Gene3D G3DSA:1.10.10.10 1 71 3.0E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS12620 3ebc8b2fb1397a1fab413af92581c93d 231 SMART SM00345 10 69 1.6E-10 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 ALX04_RS12620 3ebc8b2fb1397a1fab413af92581c93d 231 SMART SM00866 89 223 5.5E-13 T 28-03-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 ALX04_RS12620 3ebc8b2fb1397a1fab413af92581c93d 231 SUPERFAMILY SSF46785 6 78 1.33E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS12620 3ebc8b2fb1397a1fab413af92581c93d 231 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 29 43 3.8E-6 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 ALX04_RS12620 3ebc8b2fb1397a1fab413af92581c93d 231 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 43 59 3.8E-6 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 ALX04_RS12620 3ebc8b2fb1397a1fab413af92581c93d 231 Pfam PF00392 Bacterial regulatory proteins, gntR family 6 69 1.3E-15 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 ALX04_RS12620 3ebc8b2fb1397a1fab413af92581c93d 231 SUPERFAMILY SSF64288 57 228 4.4E-27 T 28-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain ALX04_RS12620 3ebc8b2fb1397a1fab413af92581c93d 231 Gene3D G3DSA:3.40.1410.10 76 228 1.1E-22 T 28-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain ALX04_RS10495 bae80a0da7b421ddde016d099cdffc6d 286 Gene3D G3DSA:3.40.50.720 84 286 4.2E-9 T 28-03-2018 ALX04_RS10495 bae80a0da7b421ddde016d099cdffc6d 286 Pfam PF05368 NmrA-like family 3 220 4.4E-21 T 28-03-2018 IPR008030 NmrA-like domain Reactome: R-HSA-70635 ALX04_RS10495 bae80a0da7b421ddde016d099cdffc6d 286 Gene3D G3DSA:3.40.50.720 1 78 3.7E-10 T 28-03-2018 ALX04_RS10495 bae80a0da7b421ddde016d099cdffc6d 286 SUPERFAMILY SSF51735 2 276 2.12E-50 T 28-03-2018 IPR016040 NAD(P)-binding domain ALX04_RS05190 80bdf7c4ee491e933a0232a7cc53fcdc 98 PIRSF PIRSF006639 1 98 1.5E-32 T 28-03-2018 IPR011379 NTP Pyrophosphohydrolase MazG-related, GP37 ALX04_RS05190 80bdf7c4ee491e933a0232a7cc53fcdc 98 Pfam PF03819 MazG nucleotide pyrophosphohydrolase domain 21 94 1.9E-12 T 28-03-2018 IPR004518 NTP pyrophosphohydrolase MazG, putative catalytic core ALX04_RS05190 80bdf7c4ee491e933a0232a7cc53fcdc 98 Gene3D G3DSA:1.10.287.1080 3 97 3.1E-13 T 28-03-2018 ALX04_RS05190 80bdf7c4ee491e933a0232a7cc53fcdc 98 SUPERFAMILY SSF101386 2 93 3.05E-19 T 28-03-2018 ALX04_RS14290 75420873c7b45208f989064e32d80511 292 Gene3D G3DSA:3.40.50.1820 40 285 2.6E-23 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold ALX04_RS14290 75420873c7b45208f989064e32d80511 292 Pfam PF06028 Alpha/beta hydrolase of unknown function (DUF915) 40 284 3.0E-55 T 28-03-2018 IPR010315 Protein of unknown function DUF915, hydrolase-like ALX04_RS14290 75420873c7b45208f989064e32d80511 292 SUPERFAMILY SSF53474 46 226 2.79E-15 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold ALX04_RS00120 ca752b5b20596dc51f593140de8f566b 222 SMART SM00855 2 163 7.7E-20 T 28-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 ALX04_RS00120 ca752b5b20596dc51f593140de8f566b 222 SUPERFAMILY SSF53254 1 221 1.57E-46 T 28-03-2018 IPR029033 Histidine phosphatase superfamily ALX04_RS00120 ca752b5b20596dc51f593140de8f566b 222 Gene3D G3DSA:3.40.50.1240 1 222 7.3E-45 T 28-03-2018 IPR029033 Histidine phosphatase superfamily ALX04_RS00120 ca752b5b20596dc51f593140de8f566b 222 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 3 217 1.1E-43 T 28-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 ALX04_RS00120 ca752b5b20596dc51f593140de8f566b 222 PIRSF PIRSF000709 1 177 2.8E-12 T 28-03-2018 ALX04_RS10955 66a8f95e6b8e3fe1a7c25c10d59b05fd 683 Pfam PF02449 Beta-galactosidase 15 395 1.5E-144 T 28-03-2018 IPR013529 Glycoside hydrolase, family 42, N-terminal GO:0004565|GO:0005975|GO:0009341 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 ALX04_RS10955 66a8f95e6b8e3fe1a7c25c10d59b05fd 683 PIRSF PIRSF001084 2 682 1.8E-266 T 28-03-2018 IPR003476 Glycoside hydrolase, family 42 GO:0004565|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 ALX04_RS10955 66a8f95e6b8e3fe1a7c25c10d59b05fd 683 Gene3D G3DSA:2.60.40.1180 623 680 8.2E-9 T 28-03-2018 ALX04_RS10955 66a8f95e6b8e3fe1a7c25c10d59b05fd 683 Gene3D G3DSA:3.40.50.880 404 616 2.9E-50 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like ALX04_RS10955 66a8f95e6b8e3fe1a7c25c10d59b05fd 683 Gene3D G3DSA:3.20.20.80 7 388 1.0E-82 T 28-03-2018 ALX04_RS10955 66a8f95e6b8e3fe1a7c25c10d59b05fd 683 SUPERFAMILY SSF52317 404 611 4.43E-51 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like ALX04_RS10955 66a8f95e6b8e3fe1a7c25c10d59b05fd 683 Pfam PF08532 Beta-galactosidase trimerisation domain 407 612 2.0E-66 T 28-03-2018 IPR013738 Beta-galactosidase trimerisation GO:0004565|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 ALX04_RS10955 66a8f95e6b8e3fe1a7c25c10d59b05fd 683 SUPERFAMILY SSF51445 9 372 1.1E-108 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily ALX04_RS10955 66a8f95e6b8e3fe1a7c25c10d59b05fd 683 Pfam PF08533 Beta-galactosidase C-terminal domain 624 679 8.9E-9 T 28-03-2018 IPR013739 Beta-galactosidase C-terminal GO:0004565|GO:0006012 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 ALX04_RS07425 6270f5965ec6e3a681df78f9ada997b5 186 Gene3D G3DSA:3.40.109.10 6 186 7.5E-38 T 28-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 ALX04_RS07425 6270f5965ec6e3a681df78f9ada997b5 186 SUPERFAMILY SSF55469 10 171 3.01E-40 T 28-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 ALX04_RS07425 6270f5965ec6e3a681df78f9ada997b5 186 Pfam PF00881 Nitroreductase family 12 166 2.4E-23 T 28-03-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 ALX04_RS10695 3e25adc7d65619c0f523eb0c806c694a 172 SUPERFAMILY SSF52949 3 167 4.04E-62 T 28-03-2018 ALX04_RS10695 3e25adc7d65619c0f523eb0c806c694a 172 SMART SM00506 3 132 9.3E-52 T 28-03-2018 IPR002589 Macro domain ALX04_RS10695 3e25adc7d65619c0f523eb0c806c694a 172 Pfam PF01661 Macro domain 20 131 1.4E-42 T 28-03-2018 IPR002589 Macro domain ALX04_RS10695 3e25adc7d65619c0f523eb0c806c694a 172 Gene3D G3DSA:3.40.220.10 1 171 4.0E-71 T 28-03-2018 ALX04_RS00685 60c472ed412241b346763c290eb37100 351 ProDom PD016147 LIGASE LYASE CITRATE PRO-3S-LYASE SYNTHETASE TRANSFERASE CYTIDYLTRANSFERASE-RELATED:CITRATE ACETATE:SH-CITRATE CITC PLASMID 121 332 1.0E-117 T 28-03-2018 ALX04_RS00685 60c472ed412241b346763c290eb37100 351 TIGRFAM TIGR00124 cit_ly_ligase: [citrate (pro-3S)-lyase] ligase 19 338 9.6E-100 T 28-03-2018 IPR005216 Citrate lyase ligase GO:0008771 ALX04_RS00685 60c472ed412241b346763c290eb37100 351 PIRSF PIRSF005751 3 349 1.2E-130 T 28-03-2018 IPR005216 Citrate lyase ligase GO:0008771 ALX04_RS00685 60c472ed412241b346763c290eb37100 351 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 153 206 2.7E-7 T 28-03-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 ALX04_RS00685 60c472ed412241b346763c290eb37100 351 Gene3D G3DSA:3.40.50.620 134 336 4.5E-25 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold ALX04_RS00685 60c472ed412241b346763c290eb37100 351 Pfam PF08218 Citrate lyase ligase C-terminal domain 151 331 1.4E-68 T 28-03-2018 IPR013166 Citrate lyase ligase, C-terminal GO:0008771 ALX04_RS00685 60c472ed412241b346763c290eb37100 351 SMART SM00764 151 331 3.0E-121 T 28-03-2018 IPR013166 Citrate lyase ligase, C-terminal GO:0008771 ALX04_RS00685 60c472ed412241b346763c290eb37100 351 SUPERFAMILY SSF52374 252 333 2.01E-21 T 28-03-2018 ALX04_RS00685 60c472ed412241b346763c290eb37100 351 SUPERFAMILY SSF52374 154 221 2.01E-21 T 28-03-2018 ALX04_RS09435 a6792ce339d210529d3627e1b14fdf00 253 Gene3D G3DSA:1.10.10.60 197 251 9.6E-14 T 28-03-2018 ALX04_RS09435 a6792ce339d210529d3627e1b14fdf00 253 Pfam PF12833 Helix-turn-helix domain 173 247 5.5E-17 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 ALX04_RS09435 a6792ce339d210529d3627e1b14fdf00 253 Gene3D G3DSA:1.10.10.60 136 196 6.6E-6 T 28-03-2018 ALX04_RS09435 a6792ce339d210529d3627e1b14fdf00 253 SUPERFAMILY SSF46689 200 247 1.75E-9 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 ALX04_RS09435 a6792ce339d210529d3627e1b14fdf00 253 SMART SM00342 161 246 1.7E-14 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 ALX04_RS06155 2ad4c892c91f9c3888676f5256c4b9b8 213 Gene3D G3DSA:3.40.50.300 1 213 7.9E-67 T 28-03-2018 ALX04_RS06155 2ad4c892c91f9c3888676f5256c4b9b8 213 Pfam PF00005 ABC transporter 18 163 1.1E-37 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 ALX04_RS06155 2ad4c892c91f9c3888676f5256c4b9b8 213 ProSitePatterns PS00211 ABC transporters family signature. 135 149 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 ALX04_RS06155 2ad4c892c91f9c3888676f5256c4b9b8 213 SUPERFAMILY SSF52540 1 208 2.53E-66 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase ALX04_RS06155 2ad4c892c91f9c3888676f5256c4b9b8 213 SMART SM00382 26 211 6.8E-15 T 28-03-2018 IPR003593 AAA+ ATPase domain ALX04_RS06510 91a4e2525fb36babe3711e8cd481e7a6 342 SUPERFAMILY SSF56752 5 336 1.06E-100 T 28-03-2018 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: R-HSA-70895 ALX04_RS06510 91a4e2525fb36babe3711e8cd481e7a6 342 Gene3D G3DSA:3.20.10.10 164 328 1.6E-38 T 28-03-2018 ALX04_RS06510 91a4e2525fb36babe3711e8cd481e7a6 342 TIGRFAM TIGR01123 ilvE_II: branched-chain amino acid aminotransferase 31 339 8.6E-134 T 28-03-2018 IPR005786 Branched-chain amino acid aminotransferase II GO:0004084|GO:0009081 KEGG: 00270+2.6.1.42|KEGG: 00280+2.6.1.42|KEGG: 00290+2.6.1.42|KEGG: 00770+2.6.1.42|KEGG: 00966+2.6.1.42|MetaCyc: PWY-5057|MetaCyc: PWY-5076|MetaCyc: PWY-5078|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5108|MetaCyc: PWY-7767|Reactome: R-HSA-70895 ALX04_RS06510 91a4e2525fb36babe3711e8cd481e7a6 342 Pfam PF01063 Amino-transferase class IV 58 292 2.6E-34 T 28-03-2018 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: R-HSA-70895 ALX04_RS06510 91a4e2525fb36babe3711e8cd481e7a6 342 PIRSF PIRSF006468 2 341 8.0E-118 T 28-03-2018 IPR005786 Branched-chain amino acid aminotransferase II GO:0004084|GO:0009081 KEGG: 00270+2.6.1.42|KEGG: 00280+2.6.1.42|KEGG: 00290+2.6.1.42|KEGG: 00770+2.6.1.42|KEGG: 00966+2.6.1.42|MetaCyc: PWY-5057|MetaCyc: PWY-5076|MetaCyc: PWY-5078|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5108|MetaCyc: PWY-7767|Reactome: R-HSA-70895 ALX04_RS06510 91a4e2525fb36babe3711e8cd481e7a6 342 ProSitePatterns PS00770 Aminotransferases class-IV signature. 220 249 - T 28-03-2018 IPR018300 Aminotransferase, class IV, conserved site GO:0003824|GO:0008152 Reactome: R-HSA-70895 ALX04_RS06510 91a4e2525fb36babe3711e8cd481e7a6 342 Gene3D G3DSA:3.30.470.10 2 163 9.3E-53 T 28-03-2018 ALX04_RS03270 a1c9b785f371ca32085c4b61facef063 269 TIGRFAM TIGR00099 Cof-subfamily: Cof-like hydrolase 5 261 4.2E-52 T 28-03-2018 IPR000150 Cof family GO:0016787 ALX04_RS03270 a1c9b785f371ca32085c4b61facef063 269 Gene3D G3DSA:3.40.50.1000 1 269 4.1E-41 T 28-03-2018 IPR023214 HAD-like domain ALX04_RS03270 a1c9b785f371ca32085c4b61facef063 269 SUPERFAMILY SSF56784 1 265 4.46E-62 T 28-03-2018 IPR023214 HAD-like domain ALX04_RS03270 a1c9b785f371ca32085c4b61facef063 269 Pfam PF08282 haloacid dehalogenase-like hydrolase 6 261 1.0E-56 T 28-03-2018 IPR023214 HAD-like domain ALX04_RS03270 a1c9b785f371ca32085c4b61facef063 269 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 181 233 2.0E-11 T 28-03-2018 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 ALX04_RS03270 a1c9b785f371ca32085c4b61facef063 269 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 5 77 5.2E-14 T 28-03-2018 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 ALX04_RS06375 2d46634a458eb194b480995253608366 401 ProSitePatterns PS00428 Cell cycle proteins ftsW / rodA / spoVE signature. 347 371 - T 28-03-2018 IPR018365 Cell cycle, FtsW / RodA / SpoVE, conserved site GO:0007049|GO:0016021 ALX04_RS06375 2d46634a458eb194b480995253608366 401 Pfam PF01098 Cell cycle protein 20 388 1.4E-84 T 28-03-2018 IPR001182 Probable peptidoglycan glycosyltransferase FtsW/RodA GO:0016021|GO:0051301 ALX04_RS02950 ffa44c12be083c1e1619396e7f276cee 339 Pfam PF02885 Glycosyl transferase family, helical bundle domain 5 64 1.7E-16 T 28-03-2018 IPR017459 Glycosyl transferase family 3, N-terminal domain Reactome: R-HSA-73614|Reactome: R-HSA-73621 ALX04_RS02950 ffa44c12be083c1e1619396e7f276cee 339 SUPERFAMILY SSF52418 72 331 2.62E-90 T 28-03-2018 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 ALX04_RS02950 ffa44c12be083c1e1619396e7f276cee 339 Hamap MF_00211 Anthranilate phosphoribosyltransferase [trpD]. 4 332 35.706 T 28-03-2018 IPR005940 Anthranilate phosphoribosyl transferase GO:0000162|GO:0004048 KEGG: 00400+2.4.2.18 ALX04_RS02950 ffa44c12be083c1e1619396e7f276cee 339 Gene3D G3DSA:1.20.970.10 2 66 3.9E-16 T 28-03-2018 ALX04_RS02950 ffa44c12be083c1e1619396e7f276cee 339 Gene3D G3DSA:3.40.1030.10 68 339 4.4E-100 T 28-03-2018 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 ALX04_RS02950 ffa44c12be083c1e1619396e7f276cee 339 TIGRFAM TIGR01245 trpD: anthranilate phosphoribosyltransferase 7 331 8.1E-116 T 28-03-2018 IPR005940 Anthranilate phosphoribosyl transferase GO:0000162|GO:0004048 KEGG: 00400+2.4.2.18 ALX04_RS02950 ffa44c12be083c1e1619396e7f276cee 339 Pfam PF00591 Glycosyl transferase family, a/b domain 73 322 1.3E-92 T 28-03-2018 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 ALX04_RS02950 ffa44c12be083c1e1619396e7f276cee 339 SUPERFAMILY SSF47648 2 68 2.35E-16 T 28-03-2018 IPR017459 Glycosyl transferase family 3, N-terminal domain Reactome: R-HSA-73614|Reactome: R-HSA-73621 ALX04_RS10190 bc7c2f59456847a597d950e49e906933 429 SUPERFAMILY SSF52540 1 425 2.34E-173 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase ALX04_RS10190 bc7c2f59456847a597d950e49e906933 429 Pfam PF00709 Adenylosuccinate synthetase 4 420 1.2E-179 T 28-03-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 ALX04_RS10190 bc7c2f59456847a597d950e49e906933 429 TIGRFAM TIGR00184 purA: adenylosuccinate synthase 5 424 7.9E-183 T 28-03-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 ALX04_RS10190 bc7c2f59456847a597d950e49e906933 429 ProSitePatterns PS00513 Adenylosuccinate synthetase active site. 131 142 - T 28-03-2018 IPR033128 Adenylosuccinate synthase, active site KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 ALX04_RS10190 bc7c2f59456847a597d950e49e906933 429 ProSitePatterns PS01266 Adenylosuccinate synthetase GTP-binding site. 10 17 - T 28-03-2018 IPR018220 Adenylosuccinate synthase, GTP-binding site GO:0005525 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 ALX04_RS10190 bc7c2f59456847a597d950e49e906933 429 Hamap MF_00011 Adenylosuccinate synthetase [purA]. 1 429 206.131 T 28-03-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 ALX04_RS10190 bc7c2f59456847a597d950e49e906933 429 Gene3D G3DSA:3.90.170.10 265 428 1.2E-67 T 28-03-2018 ALX04_RS10190 bc7c2f59456847a597d950e49e906933 429 SMART SM00788 3 422 2.8E-292 T 28-03-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 ALX04_RS10190 bc7c2f59456847a597d950e49e906933 429 Gene3D G3DSA:3.40.440.10 1 150 4.0E-52 T 28-03-2018 ALX04_RS10190 bc7c2f59456847a597d950e49e906933 429 Gene3D G3DSA:3.40.440.10 151 264 2.3E-25 T 28-03-2018 ALX04_RS00400 123b9efce3b8e093171f2facb0f52dc6 91 PRINTS PR00975 Ribosomal protein S19 family signature 65 80 3.4E-23 T 28-03-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 ALX04_RS00400 123b9efce3b8e093171f2facb0f52dc6 91 PRINTS PR00975 Ribosomal protein S19 family signature 33 52 3.4E-23 T 28-03-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 ALX04_RS00400 123b9efce3b8e093171f2facb0f52dc6 91 PRINTS PR00975 Ribosomal protein S19 family signature 53 65 3.4E-23 T 28-03-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 ALX04_RS00400 123b9efce3b8e093171f2facb0f52dc6 91 PIRSF PIRSF002144 1 91 2.6E-31 T 28-03-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 ALX04_RS00400 123b9efce3b8e093171f2facb0f52dc6 91 SUPERFAMILY SSF54570 3 84 2.09E-34 T 28-03-2018 IPR023575 Ribosomal protein S19, superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 ALX04_RS00400 123b9efce3b8e093171f2facb0f52dc6 91 TIGRFAM TIGR01050 rpsS_bact: ribosomal protein uS19 1 91 5.1E-44 T 28-03-2018 IPR005732 Ribosomal protein S19, bacterial-type GO:0003735|GO:0006412|GO:0015935 ALX04_RS00400 123b9efce3b8e093171f2facb0f52dc6 91 ProSitePatterns PS00323 Ribosomal protein S19 signature. 53 77 - T 28-03-2018 IPR020934 Ribosomal protein S19 conserved site GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 ALX04_RS00400 123b9efce3b8e093171f2facb0f52dc6 91 Pfam PF00203 Ribosomal protein S19 3 83 5.4E-35 T 28-03-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 ALX04_RS00400 123b9efce3b8e093171f2facb0f52dc6 91 Hamap MF_00531 30S ribosomal protein S19 [rpsS]. 1 89 24.827 T 28-03-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 ALX04_RS00400 123b9efce3b8e093171f2facb0f52dc6 91 Gene3D G3DSA:3.30.860.10 1 91 7.9E-39 T 28-03-2018 IPR023575 Ribosomal protein S19, superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 ALX04_RS05225 a151de52dde73a281f7176ee8981795b 290 SUPERFAMILY SSF51569 8 288 2.83E-85 T 28-03-2018 ALX04_RS05225 a151de52dde73a281f7176ee8981795b 290 PIRSF PIRSF001365 4 289 1.1E-82 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 ALX04_RS05225 a151de52dde73a281f7176ee8981795b 290 ProSitePatterns PS00666 Dihydrodipicolinate synthase signature 2. 137 167 - T 28-03-2018 IPR020625 Schiff base-forming aldolase, active site GO:0008152|GO:0016829 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|Reactome: R-HSA-389661 ALX04_RS05225 a151de52dde73a281f7176ee8981795b 290 TIGRFAM TIGR00674 dapA: 4-hydroxy-tetrahydrodipicolinate synthase 8 288 2.4E-87 T 28-03-2018 IPR005263 4-hydroxy-tetrahydrodipicolinate synthase, DapA GO:0008840|GO:0009089 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 ALX04_RS05225 a151de52dde73a281f7176ee8981795b 290 SMART SM01130 4 289 2.9E-107 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 ALX04_RS05225 a151de52dde73a281f7176ee8981795b 290 Pfam PF00701 Dihydrodipicolinate synthetase family 8 289 8.7E-89 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 ALX04_RS05225 a151de52dde73a281f7176ee8981795b 290 Hamap MF_00418 4-hydroxy-tetrahydrodipicolinate synthase [dapA]. 4 290 56.667 T 28-03-2018 IPR005263 4-hydroxy-tetrahydrodipicolinate synthase, DapA GO:0008840|GO:0009089 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 ALX04_RS05225 a151de52dde73a281f7176ee8981795b 290 PRINTS PR00146 Dihydrodipicolinate synthase signature 132 149 9.2E-30 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 ALX04_RS05225 a151de52dde73a281f7176ee8981795b 290 PRINTS PR00146 Dihydrodipicolinate synthase signature 38 59 9.2E-30 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 ALX04_RS05225 a151de52dde73a281f7176ee8981795b 290 PRINTS PR00146 Dihydrodipicolinate synthase signature 74 92 9.2E-30 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 ALX04_RS05225 a151de52dde73a281f7176ee8981795b 290 PRINTS PR00146 Dihydrodipicolinate synthase signature 107 123 9.2E-30 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 ALX04_RS05225 a151de52dde73a281f7176ee8981795b 290 ProSitePatterns PS00665 Dihydrodipicolinate synthase signature 1. 41 58 - T 28-03-2018 IPR020624 Schiff base-forming aldolase, conserved site GO:0008152|GO:0016829 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 ALX04_RS05225 a151de52dde73a281f7176ee8981795b 290 Gene3D G3DSA:3.20.20.70 6 289 1.8E-88 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 ALX04_RS01345 f09f6eb9cdd70bb4288db2faa2d033a8 341 Pfam PF06458 MucBP domain 122 176 1.0E-4 T 28-03-2018 IPR009459 MucBP domain ALX04_RS01345 f09f6eb9cdd70bb4288db2faa2d033a8 341 Pfam PF06458 MucBP domain 47 106 3.5E-5 T 28-03-2018 IPR009459 MucBP domain ALX04_RS01345 f09f6eb9cdd70bb4288db2faa2d033a8 341 Gene3D G3DSA:3.10.20.320 109 188 2.3E-8 T 28-03-2018 ALX04_RS01345 f09f6eb9cdd70bb4288db2faa2d033a8 341 Gene3D G3DSA:3.10.20.320 40 108 5.5E-9 T 28-03-2018 ALX04_RS00270 4f6a2ed5d61c8007727b0a8ac9e4385d 560 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 8 175 6.8E-48 T 28-03-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 ALX04_RS00270 4f6a2ed5d61c8007727b0a8ac9e4385d 560 Gene3D G3DSA:3.40.50.970 348 548 2.2E-39 T 28-03-2018 ALX04_RS00270 4f6a2ed5d61c8007727b0a8ac9e4385d 560 SUPERFAMILY SSF52518 2 183 7.36E-47 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold ALX04_RS00270 4f6a2ed5d61c8007727b0a8ac9e4385d 560 Gene3D G3DSA:3.40.50.970 2 197 4.3E-47 T 28-03-2018 ALX04_RS00270 4f6a2ed5d61c8007727b0a8ac9e4385d 560 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 199 330 4.8E-28 T 28-03-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 ALX04_RS00270 4f6a2ed5d61c8007727b0a8ac9e4385d 560 TIGRFAM TIGR02418 acolac_catab: acetolactate synthase, catabolic 8 551 1.5E-263 T 28-03-2018 IPR012782 Acetolactate synthase, catabolic GO:0000287|GO:0003984|GO:0030976|GO:0034077 KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111 ALX04_RS00270 4f6a2ed5d61c8007727b0a8ac9e4385d 560 Gene3D G3DSA:3.40.50.1220 198 347 8.7E-26 T 28-03-2018 IPR029035 DHS-like NAD/FAD-binding domain ALX04_RS00270 4f6a2ed5d61c8007727b0a8ac9e4385d 560 ProSitePatterns PS00187 Thiamine pyrophosphate enzymes signature. 431 450 - T 28-03-2018 IPR000399 TPP-binding enzyme, conserved site GO:0000287|GO:0030976 ALX04_RS00270 4f6a2ed5d61c8007727b0a8ac9e4385d 560 SUPERFAMILY SSF52467 191 357 8.88E-35 T 28-03-2018 IPR029035 DHS-like NAD/FAD-binding domain ALX04_RS00270 4f6a2ed5d61c8007727b0a8ac9e4385d 560 SUPERFAMILY SSF52518 373 548 1.24E-58 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold ALX04_RS00270 4f6a2ed5d61c8007727b0a8ac9e4385d 560 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 394 540 2.7E-43 T 28-03-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 ALX04_RS13925 aa09ddd3823dcb826a12aaafb0e7db95 387 Pfam PF14659 Phage integrase, N-terminal SAM-like domain 72 130 1.0E-16 T 28-03-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 ALX04_RS13925 aa09ddd3823dcb826a12aaafb0e7db95 387 Pfam PF14657 Arm DNA-binding domain 21 60 1.2E-9 T 28-03-2018 IPR028259 AP2-like integrase, N-terminal domain ALX04_RS13925 aa09ddd3823dcb826a12aaafb0e7db95 387 Gene3D G3DSA:1.10.150.130 66 177 1.9E-18 T 28-03-2018 IPR023109 Integrase/recombinase, N-terminal ALX04_RS13925 aa09ddd3823dcb826a12aaafb0e7db95 387 Gene3D G3DSA:1.10.443.10 178 386 4.6E-42 T 28-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 ALX04_RS13925 aa09ddd3823dcb826a12aaafb0e7db95 387 SUPERFAMILY SSF56349 71 378 3.83E-63 T 28-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 ALX04_RS13925 aa09ddd3823dcb826a12aaafb0e7db95 387 Pfam PF00589 Phage integrase family 189 371 1.6E-26 T 28-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 ALX04_RS14235 91a9b331423e9612ddbda91d2e0721c2 459 SUPERFAMILY SSF54211 301 455 2.2E-40 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold ALX04_RS14235 91a9b331423e9612ddbda91d2e0721c2 459 SUPERFAMILY SSF54211 253 267 2.2E-40 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold ALX04_RS14235 91a9b331423e9612ddbda91d2e0721c2 459 PRINTS PR01874 DNA repair protein radA signature 80 108 1.1E-87 T 28-03-2018 ALX04_RS14235 91a9b331423e9612ddbda91d2e0721c2 459 PRINTS PR01874 DNA repair protein radA signature 10 34 1.1E-87 T 28-03-2018 ALX04_RS14235 91a9b331423e9612ddbda91d2e0721c2 459 PRINTS PR01874 DNA repair protein radA signature 122 139 1.1E-87 T 28-03-2018 ALX04_RS14235 91a9b331423e9612ddbda91d2e0721c2 459 PRINTS PR01874 DNA repair protein radA signature 246 272 1.1E-87 T 28-03-2018 ALX04_RS14235 91a9b331423e9612ddbda91d2e0721c2 459 PRINTS PR01874 DNA repair protein radA signature 211 239 1.1E-87 T 28-03-2018 ALX04_RS14235 91a9b331423e9612ddbda91d2e0721c2 459 PRINTS PR01874 DNA repair protein radA signature 172 196 1.1E-87 T 28-03-2018 ALX04_RS14235 91a9b331423e9612ddbda91d2e0721c2 459 PRINTS PR01874 DNA repair protein radA signature 320 343 1.1E-87 T 28-03-2018 ALX04_RS14235 91a9b331423e9612ddbda91d2e0721c2 459 Pfam PF13481 AAA domain 66 220 1.7E-15 T 28-03-2018 ALX04_RS14235 91a9b331423e9612ddbda91d2e0721c2 459 SUPERFAMILY SSF52540 67 290 9.44E-51 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase ALX04_RS14235 91a9b331423e9612ddbda91d2e0721c2 459 Gene3D G3DSA:3.30.230.10 283 455 1.0E-29 T 28-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup ALX04_RS14235 91a9b331423e9612ddbda91d2e0721c2 459 Hamap MF_01498 DNA repair protein RadA [radA]. 21 454 43.994 T 28-03-2018 IPR004504 DNA repair protein RadA GO:0003684|GO:0005524|GO:0006281 ALX04_RS14235 91a9b331423e9612ddbda91d2e0721c2 459 Gene3D G3DSA:3.40.50.300 69 280 3.4E-46 T 28-03-2018 ALX04_RS14235 91a9b331423e9612ddbda91d2e0721c2 459 SMART SM00382 88 242 4.3E-11 T 28-03-2018 IPR003593 AAA+ ATPase domain ALX04_RS14235 91a9b331423e9612ddbda91d2e0721c2 459 TIGRFAM TIGR00416 sms: DNA repair protein RadA 1 450 1.7E-195 T 28-03-2018 IPR004504 DNA repair protein RadA GO:0003684|GO:0005524|GO:0006281 ALX04_RS14235 91a9b331423e9612ddbda91d2e0721c2 459 Pfam PF13541 Subunit ChlI of Mg-chelatase 362 428 2.1E-9 T 28-03-2018 ALX04_RS02195 a9ccf219b68d8b9262102983bd0cedf8 298 Gene3D G3DSA:3.10.50.40 134 239 9.1E-20 T 28-03-2018 ALX04_RS02195 a9ccf219b68d8b9262102983bd0cedf8 298 SUPERFAMILY SSF54534 137 231 3.06E-16 T 28-03-2018 ALX04_RS02195 a9ccf219b68d8b9262102983bd0cedf8 298 SUPERFAMILY SSF109998 22 163 9.42E-24 T 28-03-2018 IPR027304 Trigger factor/SurA domain ALX04_RS02195 a9ccf219b68d8b9262102983bd0cedf8 298 Pfam PF13616 PPIC-type PPIASE domain 136 231 1.2E-12 T 28-03-2018 ALX04_RS02195 a9ccf219b68d8b9262102983bd0cedf8 298 Hamap MF_01145 Foldase protein PrsA [prsA]. 2 289 22.634 T 28-03-2018 IPR023059 Foldase protein PrsA GO:0003755 ALX04_RS02195 a9ccf219b68d8b9262102983bd0cedf8 298 Gene3D G3DSA:1.10.4030.10 21 123 1.2E-10 T 28-03-2018 ALX04_RS13565 96326fc753b98e9a0812ef859c29b77e 267 Pfam PF00950 ABC 3 transport family 8 258 7.9E-47 T 28-03-2018 IPR001626 ABC transporter, TroCD-like GO:0005887|GO:0042626|GO:0043190|GO:0055085 ALX04_RS13565 96326fc753b98e9a0812ef859c29b77e 267 SUPERFAMILY SSF81345 3 256 1.57E-30 T 28-03-2018 IPR029022 ABC transporter, BtuC-like ALX04_RS13565 96326fc753b98e9a0812ef859c29b77e 267 Gene3D G3DSA:1.10.3470.10 2 265 3.0E-15 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like ALX04_RS13180 6c20e23a5e7b4b42af1b459ffc6a3fe7 508 Gene3D G3DSA:3.40.190.10 226 385 3.9E-29 T 28-03-2018 ALX04_RS13180 6c20e23a5e7b4b42af1b459ffc6a3fe7 508 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 35 203 3.0E-23 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 ALX04_RS13180 6c20e23a5e7b4b42af1b459ffc6a3fe7 508 SUPERFAMILY SSF161098 13 197 1.57E-38 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 ALX04_RS13180 6c20e23a5e7b4b42af1b459ffc6a3fe7 508 Pfam PF04069 Substrate binding domain of ABC-type glycine betaine transport system 235 498 1.4E-57 T 28-03-2018 IPR007210 ABC-type glycine betaine transport system, substrate-binding domain GO:0005215|GO:0006810 ALX04_RS13180 6c20e23a5e7b4b42af1b459ffc6a3fe7 508 Gene3D G3DSA:1.10.3720.10 2 208 1.6E-31 T 28-03-2018 ALX04_RS13180 6c20e23a5e7b4b42af1b459ffc6a3fe7 508 SUPERFAMILY SSF53850 234 504 7.6E-68 T 28-03-2018 ALX04_RS13180 6c20e23a5e7b4b42af1b459ffc6a3fe7 508 Gene3D G3DSA:3.40.190.10 386 506 1.4E-22 T 28-03-2018 ALX04_RS05840 0878b9c13c9c911cc0f0187aa17e09de 461 ProSitePatterns PS00785 5'-nucleotidase signature 1. 5 17 - T 28-03-2018 IPR006146 5'-Nucleotidase, conserved site GO:0000166|GO:0016788|GO:0046872 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 ALX04_RS05840 0878b9c13c9c911cc0f0187aa17e09de 461 Gene3D G3DSA:3.90.780.10 295 461 6.5E-16 T 28-03-2018 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 ALX04_RS05840 0878b9c13c9c911cc0f0187aa17e09de 461 PIRSF PIRSF036361 1 459 1.0E-192 T 28-03-2018 IPR011240 Phosphoesterase-related protein YunD ALX04_RS05840 0878b9c13c9c911cc0f0187aa17e09de 461 Pfam PF02872 5'-nucleotidase, C-terminal domain 297 422 1.2E-10 T 28-03-2018 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 ALX04_RS05840 0878b9c13c9c911cc0f0187aa17e09de 461 SUPERFAMILY SSF55816 282 459 8.11E-20 T 28-03-2018 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 ALX04_RS05840 0878b9c13c9c911cc0f0187aa17e09de 461 Pfam PF00149 Calcineurin-like phosphoesterase 6 206 4.5E-10 T 28-03-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 ALX04_RS05840 0878b9c13c9c911cc0f0187aa17e09de 461 PRINTS PR01607 Apyrase family signature 3 21 1.1E-20 T 28-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 ALX04_RS05840 0878b9c13c9c911cc0f0187aa17e09de 461 PRINTS PR01607 Apyrase family signature 189 212 1.1E-20 T 28-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 ALX04_RS05840 0878b9c13c9c911cc0f0187aa17e09de 461 PRINTS PR01607 Apyrase family signature 330 353 1.1E-20 T 28-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 ALX04_RS05840 0878b9c13c9c911cc0f0187aa17e09de 461 PRINTS PR01607 Apyrase family signature 170 187 1.1E-20 T 28-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 ALX04_RS05840 0878b9c13c9c911cc0f0187aa17e09de 461 PRINTS PR01607 Apyrase family signature 408 427 1.1E-20 T 28-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 ALX04_RS05840 0878b9c13c9c911cc0f0187aa17e09de 461 PRINTS PR01607 Apyrase family signature 217 237 1.1E-20 T 28-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 ALX04_RS05840 0878b9c13c9c911cc0f0187aa17e09de 461 Gene3D G3DSA:3.60.21.10 2 294 1.7E-53 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like ALX04_RS05840 0878b9c13c9c911cc0f0187aa17e09de 461 SUPERFAMILY SSF56300 4 276 5.57E-62 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like ALX04_RS15590 8b6f4fac0677cefa67e67660eab8ee1d 510 Pfam PF08708 Primase C terminal 1 (PriCT-1) 277 328 2.2E-8 T 28-03-2018 IPR014820 Primase, C-terminal 1 ALX04_RS15590 8b6f4fac0677cefa67e67660eab8ee1d 510 Gene3D G3DSA:1.10.10.10 356 447 1.4E-5 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS14380 c084b845801ab14fe9e3d6fed597e92b 83 Pfam PF10704 Protein of unknown function (DUF2508) 1 72 2.3E-23 T 28-03-2018 IPR019644 Protein of unknown function DUF2508 ALX04_RS06090 bd962d1afe21e520ac2ac60dedf995f1 896 Gene3D G3DSA:1.10.1420.10 399 527 7.5E-34 T 28-03-2018 ALX04_RS06090 bd962d1afe21e520ac2ac60dedf995f1 896 SUPERFAMILY SSF53150 118 269 8.5E-29 T 28-03-2018 IPR007860 DNA mismatch repair protein MutS, connector domain GO:0005524|GO:0006298|GO:0030983 ALX04_RS06090 bd962d1afe21e520ac2ac60dedf995f1 896 SMART SM00534 600 787 4.1E-114 T 28-03-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 ALX04_RS06090 bd962d1afe21e520ac2ac60dedf995f1 896 SUPERFAMILY SSF55271 5 115 1.44E-42 T 28-03-2018 IPR016151 DNA mismatch repair protein MutS, N-terminal GO:0005524|GO:0006298|GO:0030983 Reactome: R-HSA-5632928 ALX04_RS06090 bd962d1afe21e520ac2ac60dedf995f1 896 Gene3D G3DSA:3.30.420.110 132 252 2.0E-19 T 28-03-2018 IPR007860 DNA mismatch repair protein MutS, connector domain GO:0005524|GO:0006298|GO:0030983 ALX04_RS06090 bd962d1afe21e520ac2ac60dedf995f1 896 Pfam PF05188 MutS domain II 128 248 5.1E-11 T 28-03-2018 IPR007860 DNA mismatch repair protein MutS, connector domain GO:0005524|GO:0006298|GO:0030983 ALX04_RS06090 bd962d1afe21e520ac2ac60dedf995f1 896 SMART SM00533 274 583 6.5E-105 T 28-03-2018 IPR007696 DNA mismatch repair protein MutS, core GO:0005524|GO:0006298|GO:0030983 ALX04_RS06090 bd962d1afe21e520ac2ac60dedf995f1 896 SUPERFAMILY SSF52540 559 791 1.65E-63 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase ALX04_RS06090 bd962d1afe21e520ac2ac60dedf995f1 896 Hamap MF_00096 DNA mismatch repair protein MutS [mutS]. 7 886 25.103 T 28-03-2018 IPR005748 DNA mismatch repair protein MutS GO:0005524|GO:0006298|GO:0030983 ALX04_RS06090 bd962d1afe21e520ac2ac60dedf995f1 896 Pfam PF05190 MutS family domain IV 419 510 1.1E-30 T 28-03-2018 IPR007861 DNA mismatch repair protein MutS, clamp GO:0005524|GO:0006298|GO:0030983 ALX04_RS06090 bd962d1afe21e520ac2ac60dedf995f1 896 TIGRFAM TIGR01070 mutS1: DNA mismatch repair protein MutS 8 892 0.0 T 28-03-2018 IPR005748 DNA mismatch repair protein MutS GO:0005524|GO:0006298|GO:0030983 ALX04_RS06090 bd962d1afe21e520ac2ac60dedf995f1 896 Gene3D G3DSA:3.40.50.300 559 825 7.0E-47 T 28-03-2018 ALX04_RS06090 bd962d1afe21e520ac2ac60dedf995f1 896 PIRSF PIRSF037677 1 239 9.8E-32 T 28-03-2018 IPR017261 DNA mismatch repair protein MutS/MSH GO:0006298|GO:0030983 ALX04_RS06090 bd962d1afe21e520ac2ac60dedf995f1 896 PIRSF PIRSF037677 226 840 1.6E-133 T 28-03-2018 IPR017261 DNA mismatch repair protein MutS/MSH GO:0006298|GO:0030983 ALX04_RS06090 bd962d1afe21e520ac2ac60dedf995f1 896 Gene3D G3DSA:1.10.1420.10 253 398 4.4E-35 T 28-03-2018 ALX04_RS06090 bd962d1afe21e520ac2ac60dedf995f1 896 Pfam PF01624 MutS domain I 8 118 3.4E-43 T 28-03-2018 IPR007695 DNA mismatch repair protein MutS-like, N-terminal GO:0005524|GO:0006298|GO:0030983 Reactome: R-HSA-5632928 ALX04_RS06090 bd962d1afe21e520ac2ac60dedf995f1 896 Gene3D G3DSA:3.40.1170.10 2 131 1.1E-44 T 28-03-2018 IPR016151 DNA mismatch repair protein MutS, N-terminal GO:0005524|GO:0006298|GO:0030983 Reactome: R-HSA-5632928 ALX04_RS06090 bd962d1afe21e520ac2ac60dedf995f1 896 Pfam PF00488 MutS domain V 604 790 1.6E-82 T 28-03-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 ALX04_RS06090 bd962d1afe21e520ac2ac60dedf995f1 896 Pfam PF05192 MutS domain III 262 551 1.0E-40 T 28-03-2018 IPR007696 DNA mismatch repair protein MutS, core GO:0005524|GO:0006298|GO:0030983 ALX04_RS06090 bd962d1afe21e520ac2ac60dedf995f1 896 SUPERFAMILY SSF48334 257 557 3.4E-89 T 28-03-2018 IPR007696 DNA mismatch repair protein MutS, core GO:0005524|GO:0006298|GO:0030983 ALX04_RS07135 bb448ea3a1eb8ccd09c4ec1f39fbc30b 247 SUPERFAMILY SSF55811 9 126 7.56E-22 T 28-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 ALX04_RS07135 bb448ea3a1eb8ccd09c4ec1f39fbc30b 247 Gene3D G3DSA:1.10.10.10 180 247 2.2E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS07135 bb448ea3a1eb8ccd09c4ec1f39fbc30b 247 SUPERFAMILY SSF46785 183 243 5.85E-23 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS07135 bb448ea3a1eb8ccd09c4ec1f39fbc30b 247 Pfam PF00293 NUDIX domain 25 123 1.6E-7 T 28-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 ALX04_RS07135 bb448ea3a1eb8ccd09c4ec1f39fbc30b 247 Gene3D G3DSA:3.90.79.10 5 179 4.4E-24 T 28-03-2018 ALX04_RS12445 0ce097b376ba02a3d8232ecbaa39587c 207 SMART SM00855 3 163 3.2E-14 T 28-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 ALX04_RS12445 0ce097b376ba02a3d8232ecbaa39587c 207 Gene3D G3DSA:3.40.50.1240 1 204 3.2E-40 T 28-03-2018 IPR029033 Histidine phosphatase superfamily ALX04_RS12445 0ce097b376ba02a3d8232ecbaa39587c 207 ProSitePatterns PS00175 Phosphoglycerate mutase family phosphohistidine signature. 6 15 - T 28-03-2018 IPR001345 Phosphoglycerate/bisphosphoglycerate mutase, active site GO:0003824|GO:0008152 ALX04_RS12445 0ce097b376ba02a3d8232ecbaa39587c 207 SUPERFAMILY SSF53254 1 204 7.9E-43 T 28-03-2018 IPR029033 Histidine phosphatase superfamily ALX04_RS12445 0ce097b376ba02a3d8232ecbaa39587c 207 PIRSF PIRSF000709 2 169 1.3E-7 T 28-03-2018 ALX04_RS12445 0ce097b376ba02a3d8232ecbaa39587c 207 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 4 191 1.3E-39 T 28-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 ALX04_RS02455 2d8fc3fcb270e70025b535d88990d71e 478 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 7 177 1.6E-51 T 28-03-2018 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0004616|GO:0055114 ALX04_RS02455 2d8fc3fcb270e70025b535d88990d71e 478 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 364 386 1.2E-83 T 28-03-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 ALX04_RS02455 2d8fc3fcb270e70025b535d88990d71e 478 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 171 199 1.2E-83 T 28-03-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 ALX04_RS02455 2d8fc3fcb270e70025b535d88990d71e 478 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 68 97 1.2E-83 T 28-03-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 ALX04_RS02455 2d8fc3fcb270e70025b535d88990d71e 478 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 256 283 1.2E-83 T 28-03-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 ALX04_RS02455 2d8fc3fcb270e70025b535d88990d71e 478 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 121 146 1.2E-83 T 28-03-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 ALX04_RS02455 2d8fc3fcb270e70025b535d88990d71e 478 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 6 29 1.2E-83 T 28-03-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 ALX04_RS02455 2d8fc3fcb270e70025b535d88990d71e 478 Gene3D G3DSA:1.20.5.320 443 476 1.0E-18 T 28-03-2018 ALX04_RS02455 2d8fc3fcb270e70025b535d88990d71e 478 TIGRFAM TIGR00873 gnd: 6-phosphogluconate dehydrogenase (decarboxylating) 7 475 1.0E-209 T 28-03-2018 IPR006113 6-phosphogluconate dehydrogenase, decarboxylating GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 ALX04_RS02455 2d8fc3fcb270e70025b535d88990d71e 478 SUPERFAMILY SSF48179 180 477 1.23E-125 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 ALX04_RS02455 2d8fc3fcb270e70025b535d88990d71e 478 PIRSF PIRSF000109 1 478 1.6E-225 T 28-03-2018 IPR006113 6-phosphogluconate dehydrogenase, decarboxylating GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 ALX04_RS02455 2d8fc3fcb270e70025b535d88990d71e 478 SMART SM01350 182 475 7.6E-204 T 28-03-2018 IPR006114 6-phosphogluconate dehydrogenase, C-terminal GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 ALX04_RS02455 2d8fc3fcb270e70025b535d88990d71e 478 Pfam PF00393 6-phosphogluconate dehydrogenase, C-terminal domain 182 474 3.3E-126 T 28-03-2018 IPR006114 6-phosphogluconate dehydrogenase, C-terminal GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 ALX04_RS02455 2d8fc3fcb270e70025b535d88990d71e 478 Gene3D G3DSA:3.40.50.720 2 183 4.8E-33 T 28-03-2018 ALX04_RS02455 2d8fc3fcb270e70025b535d88990d71e 478 Gene3D G3DSA:1.10.1040.10 184 442 3.9E-104 T 28-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 ALX04_RS02455 2d8fc3fcb270e70025b535d88990d71e 478 SUPERFAMILY SSF51735 7 169 4.42E-51 T 28-03-2018 IPR016040 NAD(P)-binding domain ALX04_RS11150 1403dd55c2d8dbdbb22b3b075731bbc7 362 Pfam PF05913 Bacterial protein of unknown function (DUF871) 5 360 9.3E-129 T 28-03-2018 IPR008589 Protein of unknown function DUF871, prokaryotic ALX04_RS11150 1403dd55c2d8dbdbb22b3b075731bbc7 362 Gene3D G3DSA:2.40.100.10 246 361 3.0E-34 T 28-03-2018 IPR029000 Cyclophilin-like domain ALX04_RS11150 1403dd55c2d8dbdbb22b3b075731bbc7 362 SUPERFAMILY SSF50891 247 361 2.96E-35 T 28-03-2018 IPR029000 Cyclophilin-like domain ALX04_RS11150 1403dd55c2d8dbdbb22b3b075731bbc7 362 SUPERFAMILY SSF51445 3 244 1.37E-85 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily ALX04_RS11150 1403dd55c2d8dbdbb22b3b075731bbc7 362 Gene3D G3DSA:3.20.20.70 5 240 4.6E-87 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 ALX04_RS02515 c1709c713dc8fdef6712add5fe501201 119 Pfam PF01638 HxlR-like helix-turn-helix 28 116 1.7E-24 T 28-03-2018 IPR002577 Helix-turn-helix, HxlR type ALX04_RS02515 c1709c713dc8fdef6712add5fe501201 119 Gene3D G3DSA:1.10.10.10 12 119 1.8E-13 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS02515 c1709c713dc8fdef6712add5fe501201 119 SUPERFAMILY SSF46785 15 115 2.82E-26 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS07410 0a91cc738159ec132313a49f5337324c 254 Pfam PF06028 Alpha/beta hydrolase of unknown function (DUF915) 37 175 2.3E-26 T 28-03-2018 IPR010315 Protein of unknown function DUF915, hydrolase-like ALX04_RS07410 0a91cc738159ec132313a49f5337324c 254 SUPERFAMILY SSF53474 46 225 1.27E-9 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold ALX04_RS07410 0a91cc738159ec132313a49f5337324c 254 Gene3D G3DSA:3.40.50.1820 26 254 4.1E-15 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold ALX04_RS08075 39cf151c2994bbd535ac7db217dd4404 211 Gene3D G3DSA:2.160.20.80 4 127 4.8E-20 T 28-03-2018 ALX04_RS08075 39cf151c2994bbd535ac7db217dd4404 211 Gene3D G3DSA:2.160.10.20 128 208 1.4E-7 T 28-03-2018 ALX04_RS08075 39cf151c2994bbd535ac7db217dd4404 211 Pfam PF13599 Pentapeptide repeats (9 copies) 75 143 3.8E-14 T 28-03-2018 IPR001646 Pentapeptide repeat ALX04_RS08075 39cf151c2994bbd535ac7db217dd4404 211 SUPERFAMILY SSF141571 32 204 8.76E-38 T 28-03-2018 ALX04_RS02480 c3e48da77669d5c9352a1c0c104b3c3f 1061 Gene3D G3DSA:3.40.50.300 877 1055 5.0E-4 T 28-03-2018 ALX04_RS02480 c3e48da77669d5c9352a1c0c104b3c3f 1061 SUPERFAMILY SSF52540 27 197 5.08E-20 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase ALX04_RS02480 c3e48da77669d5c9352a1c0c104b3c3f 1061 SUPERFAMILY SSF52540 953 1045 5.08E-20 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase ALX04_RS02480 c3e48da77669d5c9352a1c0c104b3c3f 1061 Pfam PF13558 Putative exonuclease SbcCD, C subunit 938 1019 5.5E-14 T 28-03-2018 ALX04_RS02480 c3e48da77669d5c9352a1c0c104b3c3f 1061 Gene3D G3DSA:3.40.50.300 4 200 1.7E-22 T 28-03-2018 ALX04_RS02480 c3e48da77669d5c9352a1c0c104b3c3f 1061 Pfam PF13476 AAA domain 7 298 1.0E-19 T 28-03-2018 ALX04_RS02480 c3e48da77669d5c9352a1c0c104b3c3f 1061 Gene3D G3DSA:1.20.5.340 390 526 0.014 T 28-03-2018 ALX04_RS02480 c3e48da77669d5c9352a1c0c104b3c3f 1061 Gene3D G3DSA:1.20.5.340 773 876 0.0031 T 28-03-2018 ALX04_RS02480 c3e48da77669d5c9352a1c0c104b3c3f 1061 Gene3D G3DSA:1.20.5.340 693 768 7.2E-4 T 28-03-2018 ALX04_RS02480 c3e48da77669d5c9352a1c0c104b3c3f 1061 Gene3D G3DSA:1.20.120.330 536 692 7.0E-6 T 28-03-2018 ALX04_RS15800 304f23a228365e9cfbac6ea2b8093057 133 SUPERFAMILY SSF52374 1 124 6.14E-34 T 28-03-2018 ALX04_RS15800 304f23a228365e9cfbac6ea2b8093057 133 TIGRFAM TIGR01518 g3p_cytidyltrns: glycerol-3-phosphate cytidylyltransferase 4 126 1.6E-59 T 28-03-2018 IPR006409 Glycerol-3-phosphate cytidylyltransferase GO:0005737|GO:0019350|GO:0046872|GO:0047348 ALX04_RS15800 304f23a228365e9cfbac6ea2b8093057 133 Gene3D G3DSA:3.40.50.620 1 126 6.7E-29 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold ALX04_RS15800 304f23a228365e9cfbac6ea2b8093057 133 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 4 68 3.9E-19 T 28-03-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 ALX04_RS15800 304f23a228365e9cfbac6ea2b8093057 133 Pfam PF01467 Cytidylyltransferase-like 5 123 6.5E-20 T 28-03-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 ALX04_RS01280 7663d6b56e86ab980bd3d770b4e82ef6 125 Pfam PF01381 Helix-turn-helix 15 66 1.4E-7 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 ALX04_RS01280 7663d6b56e86ab980bd3d770b4e82ef6 125 Gene3D G3DSA:1.10.260.40 4 124 2.2E-14 T 28-03-2018 ALX04_RS01280 7663d6b56e86ab980bd3d770b4e82ef6 125 SUPERFAMILY SSF47413 11 73 1.3E-9 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 ALX04_RS01280 7663d6b56e86ab980bd3d770b4e82ef6 125 SMART SM00530 14 67 3.2E-9 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 ALX04_RS01215 72ed400ed23b95b298cd0ff81293c761 472 Pfam PF01943 Polysaccharide biosynthesis protein 4 268 4.4E-19 T 28-03-2018 IPR002797 Polysaccharide biosynthesis protein GO:0016020 ALX04_RS01215 72ed400ed23b95b298cd0ff81293c761 472 Pfam PF14667 Polysaccharide biosynthesis C-terminal domain 321 457 1.9E-26 T 28-03-2018 IPR029303 Polysaccharide biosynthesis protein, C-terminal domain ALX04_RS09945 21c8ea23ba6abd9343003eddfb29410b 235 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 34 228 1.0E-22 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 ALX04_RS09945 21c8ea23ba6abd9343003eddfb29410b 235 SUPERFAMILY SSF161098 17 213 1.24E-43 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 ALX04_RS09945 21c8ea23ba6abd9343003eddfb29410b 235 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 17 122 1.6E-23 T 28-03-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 ALX04_RS09945 21c8ea23ba6abd9343003eddfb29410b 235 Gene3D G3DSA:1.10.3720.10 3 233 4.6E-39 T 28-03-2018 ALX04_RS04445 daa75914b8b0a3c7a5104a50c4ed5705 755 Gene3D G3DSA:3.30.460.10 193 332 5.4E-45 T 28-03-2018 ALX04_RS04445 daa75914b8b0a3c7a5104a50c4ed5705 755 Pfam PF13328 HD domain 31 180 2.0E-49 T 28-03-2018 IPR003607 HD/PDEase domain ALX04_RS04445 daa75914b8b0a3c7a5104a50c4ed5705 755 SUPERFAMILY SSF81301 197 372 6.87E-65 T 28-03-2018 ALX04_RS04445 daa75914b8b0a3c7a5104a50c4ed5705 755 SUPERFAMILY SSF81271 383 455 9.16E-22 T 28-03-2018 IPR012676 TGS-like KEGG: 00970+6.1.1.3 ALX04_RS04445 daa75914b8b0a3c7a5104a50c4ed5705 755 Gene3D G3DSA:3.30.70.260 676 754 2.7E-4 T 28-03-2018 ALX04_RS04445 daa75914b8b0a3c7a5104a50c4ed5705 755 Pfam PF13291 ACT domain 676 752 7.2E-18 T 28-03-2018 IPR002912 ACT domain ALX04_RS04445 daa75914b8b0a3c7a5104a50c4ed5705 755 SMART SM00954 241 351 1.5E-70 T 28-03-2018 IPR007685 RelA/SpoT GO:0015969 ALX04_RS04445 daa75914b8b0a3c7a5104a50c4ed5705 755 TIGRFAM TIGR00691 spoT_relA: RelA/SpoT family protein 31 751 3.9E-244 T 28-03-2018 IPR004811 RelA/SpoT family GO:0015969 ALX04_RS04445 daa75914b8b0a3c7a5104a50c4ed5705 755 Pfam PF02824 TGS domain 396 455 5.5E-20 T 28-03-2018 IPR004095 TGS KEGG: 00970+6.1.1.3 ALX04_RS04445 daa75914b8b0a3c7a5104a50c4ed5705 755 SMART SM00471 46 158 5.0E-10 T 28-03-2018 IPR003607 HD/PDEase domain ALX04_RS04445 daa75914b8b0a3c7a5104a50c4ed5705 755 Pfam PF04607 Region found in RelA / SpoT proteins 241 351 1.4E-40 T 28-03-2018 IPR007685 RelA/SpoT GO:0015969 ALX04_RS04445 daa75914b8b0a3c7a5104a50c4ed5705 755 Gene3D G3DSA:3.10.20.30 390 463 1.1E-22 T 28-03-2018 IPR012675 Beta-grasp domain ALX04_RS04445 daa75914b8b0a3c7a5104a50c4ed5705 755 SUPERFAMILY SSF109604 9 196 4.39E-75 T 28-03-2018 ALX04_RS02525 a8e756385eb77b12a699856edbb8c79a 805 Pfam PF03483 B3/4 domain 224 394 7.7E-62 T 28-03-2018 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 ALX04_RS02525 a8e756385eb77b12a699856edbb8c79a 805 SMART SM00896 712 805 2.5E-41 T 28-03-2018 IPR005121 Ferrodoxin-fold anticodon-binding domain KEGG: 00970+6.1.1.20 ALX04_RS02525 a8e756385eb77b12a699856edbb8c79a 805 SUPERFAMILY SSF55681 476 699 1.99E-48 T 28-03-2018 ALX04_RS02525 a8e756385eb77b12a699856edbb8c79a 805 Gene3D G3DSA:3.50.40.10 204 404 6.6E-65 T 28-03-2018 IPR020825 Phenylalanyl-tRNA synthetase, B3/B4 ALX04_RS02525 a8e756385eb77b12a699856edbb8c79a 805 SUPERFAMILY SSF56037 218 405 1.1E-65 T 28-03-2018 IPR020825 Phenylalanyl-tRNA synthetase, B3/B4 ALX04_RS02525 a8e756385eb77b12a699856edbb8c79a 805 SUPERFAMILY SSF50249 41 198 3.67E-48 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold ALX04_RS02525 a8e756385eb77b12a699856edbb8c79a 805 Gene3D G3DSA:2.40.50.140 54 160 3.1E-43 T 28-03-2018 ALX04_RS02525 a8e756385eb77b12a699856edbb8c79a 805 SUPERFAMILY SSF54991 707 805 2.62E-29 T 28-03-2018 IPR005121 Ferrodoxin-fold anticodon-binding domain KEGG: 00970+6.1.1.20 ALX04_RS02525 a8e756385eb77b12a699856edbb8c79a 805 Gene3D G3DSA:3.30.56.10 411 484 8.6E-23 T 28-03-2018 ALX04_RS02525 a8e756385eb77b12a699856edbb8c79a 805 SMART SM00873 222 395 5.0E-81 T 28-03-2018 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 ALX04_RS02525 a8e756385eb77b12a699856edbb8c79a 805 Hamap MF_00283 Phenylalanine--tRNA ligase beta subunit [pheT]. 1 799 43.338 T 28-03-2018 IPR004532 Phenylalanine-tRNA ligase, class IIc, beta subunit GO:0000287|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 ALX04_RS02525 a8e756385eb77b12a699856edbb8c79a 805 Pfam PF03147 Ferredoxin-fold anticodon binding domain 712 805 1.0E-28 T 28-03-2018 IPR005121 Ferrodoxin-fold anticodon-binding domain KEGG: 00970+6.1.1.20 ALX04_RS02525 a8e756385eb77b12a699856edbb8c79a 805 Gene3D G3DSA:3.30.56.10 1 53 9.7E-12 T 28-03-2018 ALX04_RS02525 a8e756385eb77b12a699856edbb8c79a 805 Pfam PF03484 tRNA synthetase B5 domain 415 480 4.4E-19 T 28-03-2018 IPR005147 tRNA synthetase, B5-domain GO:0000287|GO:0003723|GO:0005524|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 ALX04_RS02525 a8e756385eb77b12a699856edbb8c79a 805 SMART SM00874 412 480 3.0E-30 T 28-03-2018 IPR005147 tRNA synthetase, B5-domain GO:0000287|GO:0003723|GO:0005524|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 ALX04_RS02525 a8e756385eb77b12a699856edbb8c79a 805 Pfam PF01588 Putative tRNA binding domain 45 151 5.9E-24 T 28-03-2018 IPR002547 tRNA-binding domain GO:0000049 Reactome: R-HSA-379716 ALX04_RS02525 a8e756385eb77b12a699856edbb8c79a 805 TIGRFAM TIGR00472 pheT_bact: phenylalanine--tRNA ligase, beta subunit 1 805 4.9E-295 T 28-03-2018 IPR004532 Phenylalanine-tRNA ligase, class IIc, beta subunit GO:0000287|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 ALX04_RS02525 a8e756385eb77b12a699856edbb8c79a 805 Gene3D G3DSA:3.30.70.380 708 805 1.2E-25 T 28-03-2018 IPR005121 Ferrodoxin-fold anticodon-binding domain KEGG: 00970+6.1.1.20 ALX04_RS02525 a8e756385eb77b12a699856edbb8c79a 805 Gene3D G3DSA:3.30.930.10 498 699 7.2E-34 T 28-03-2018 ALX04_RS02525 a8e756385eb77b12a699856edbb8c79a 805 SUPERFAMILY SSF46955 412 484 5.95E-21 T 28-03-2018 IPR009061 Putative DNA-binding domain ALX04_RS00020 4109347d9958b07eaffd988aae01b50c 250 SUPERFAMILY SSF47413 2 65 1.18E-16 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 ALX04_RS00020 4109347d9958b07eaffd988aae01b50c 250 Gene3D G3DSA:1.10.3100.10 1 66 3.0E-17 T 28-03-2018 IPR027910 YdiL-like domain ALX04_RS00020 4109347d9958b07eaffd988aae01b50c 250 SMART SM00530 6 61 1.1E-16 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 ALX04_RS00020 4109347d9958b07eaffd988aae01b50c 250 Pfam PF01381 Helix-turn-helix 7 61 4.9E-16 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 ALX04_RS04425 c71511c9f81f23defd8101ee11caf0d4 282 Pfam PF01520 N-acetylmuramoyl-L-alanine amidase 108 276 1.5E-46 T 28-03-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 ALX04_RS04425 c71511c9f81f23defd8101ee11caf0d4 282 PIRSF PIRSF037730 1 281 7.8E-115 T 28-03-2018 IPR017273 Probable cell wall amidase LytH GO:0005576|GO:0016811|GO:0071555 ALX04_RS04425 c71511c9f81f23defd8101ee11caf0d4 282 Gene3D G3DSA:3.40.630.40 97 282 4.4E-54 T 28-03-2018 ALX04_RS04425 c71511c9f81f23defd8101ee11caf0d4 282 SMART SM00287 31 93 1.8E-5 T 28-03-2018 IPR003646 SH3-like domain, bacterial-type ALX04_RS04425 c71511c9f81f23defd8101ee11caf0d4 282 SMART SM00646 167 276 1.9E-20 T 28-03-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 ALX04_RS04425 c71511c9f81f23defd8101ee11caf0d4 282 SUPERFAMILY SSF53187 106 279 1.0E-48 T 28-03-2018 ALX04_RS04425 c71511c9f81f23defd8101ee11caf0d4 282 Pfam PF08239 Bacterial SH3 domain 40 90 1.2E-7 T 28-03-2018 IPR003646 SH3-like domain, bacterial-type ALX04_RS04425 c71511c9f81f23defd8101ee11caf0d4 282 Gene3D G3DSA:2.30.30.410 27 96 3.9E-14 T 28-03-2018 ALX04_RS03730 65185dd072e84bea04bfb9327298631f 171 SUPERFAMILY SSF55068 2 156 1.83E-67 T 28-03-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 ALX04_RS03730 65185dd072e84bea04bfb9327298631f 171 Gene3D G3DSA:3.30.1060.10 1 169 2.0E-62 T 28-03-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 ALX04_RS03730 65185dd072e84bea04bfb9327298631f 171 Hamap MF_01401 Peptide methionine sulfoxide reductase MsrA [msrA]. 2 161 34.853 T 28-03-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 ALX04_RS03730 65185dd072e84bea04bfb9327298631f 171 TIGRFAM TIGR00401 msrA: peptide-methionine (S)-S-oxide reductase 3 154 5.5E-59 T 28-03-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 ALX04_RS03730 65185dd072e84bea04bfb9327298631f 171 Pfam PF01625 Peptide methionine sulfoxide reductase 4 155 1.6E-57 T 28-03-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 ALX04_RS12510 fb129b92214158d5b7e39a53204d5071 161 PIRSF PIRSF000303 1 159 9.9E-62 T 28-03-2018 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 ALX04_RS12510 fb129b92214158d5b7e39a53204d5071 161 SUPERFAMILY SSF52833 4 156 8.75E-53 T 28-03-2018 IPR012336 Thioredoxin-like fold ALX04_RS12510 fb129b92214158d5b7e39a53204d5071 161 PRINTS PR01011 Glutathione peroxidase family signature 119 128 1.4E-13 T 28-03-2018 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 ALX04_RS12510 fb129b92214158d5b7e39a53204d5071 161 PRINTS PR01011 Glutathione peroxidase family signature 58 74 1.4E-13 T 28-03-2018 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 ALX04_RS12510 fb129b92214158d5b7e39a53204d5071 161 PRINTS PR01011 Glutathione peroxidase family signature 23 40 1.4E-13 T 28-03-2018 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 ALX04_RS12510 fb129b92214158d5b7e39a53204d5071 161 Pfam PF00255 Glutathione peroxidase 5 111 2.7E-35 T 28-03-2018 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 ALX04_RS12510 fb129b92214158d5b7e39a53204d5071 161 ProSitePatterns PS00460 Glutathione peroxidases active site. 25 40 - T 28-03-2018 IPR029759 Glutathione peroxidase active site Reactome: R-HSA-3299685 ALX04_RS12510 fb129b92214158d5b7e39a53204d5071 161 Gene3D G3DSA:3.40.30.10 3 157 9.8E-41 T 28-03-2018 ALX04_RS14255 1f800ec7603ec4a6a3f5b971ac38f274 136 PIRSF PIRSF005520 1 133 1.7E-52 T 28-03-2018 IPR008226 Mini-ribonuclease 3 family ALX04_RS14255 1f800ec7603ec4a6a3f5b971ac38f274 136 Gene3D G3DSA:1.10.1520.10 2 135 6.4E-18 T 28-03-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 ALX04_RS14255 1f800ec7603ec4a6a3f5b971ac38f274 136 Hamap MF_01468 Mini-ribonuclease 3 [mrnC]. 2 128 28.243 T 28-03-2018 IPR008226 Mini-ribonuclease 3 family ALX04_RS14255 1f800ec7603ec4a6a3f5b971ac38f274 136 SUPERFAMILY SSF69065 4 127 1.29E-42 T 28-03-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 ALX04_RS14255 1f800ec7603ec4a6a3f5b971ac38f274 136 Pfam PF00636 Ribonuclease III domain 12 111 6.3E-15 T 28-03-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 ALX04_RS09535 93eda4d60e92395d21f3db0b9ecd3aa2 633 PIRSF PIRSF001589 1 630 3.6E-217 T 28-03-2018 IPR006426 Asparagine synthase, glutamine-hydrolyzing GO:0004066|GO:0006529 KEGG: 00250+6.3.5.4|Reactome: R-HSA-380994|Reactome: R-HSA-70614 ALX04_RS09535 93eda4d60e92395d21f3db0b9ecd3aa2 633 TIGRFAM TIGR01536 asn_synth_AEB: asparagine synthase (glutamine-hydrolyzing) 2 546 1.3E-161 T 28-03-2018 IPR006426 Asparagine synthase, glutamine-hydrolyzing GO:0004066|GO:0006529 KEGG: 00250+6.3.5.4|Reactome: R-HSA-380994|Reactome: R-HSA-70614 ALX04_RS09535 93eda4d60e92395d21f3db0b9ecd3aa2 633 Pfam PF13537 Glutamine amidotransferase domain 51 167 9.4E-44 T 28-03-2018 IPR017932 Glutamine amidotransferase type 2 domain ALX04_RS09535 93eda4d60e92395d21f3db0b9ecd3aa2 633 SUPERFAMILY SSF52402 228 380 2.79E-84 T 28-03-2018 ALX04_RS09535 93eda4d60e92395d21f3db0b9ecd3aa2 633 SUPERFAMILY SSF52402 466 604 2.79E-84 T 28-03-2018 ALX04_RS09535 93eda4d60e92395d21f3db0b9ecd3aa2 633 Gene3D G3DSA:3.40.50.620 223 616 3.8E-77 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold ALX04_RS09535 93eda4d60e92395d21f3db0b9ecd3aa2 633 Pfam PF00733 Asparagine synthase 241 609 5.2E-103 T 28-03-2018 IPR001962 Asparagine synthase GO:0004066|GO:0006529 ALX04_RS09535 93eda4d60e92395d21f3db0b9ecd3aa2 633 SUPERFAMILY SSF56235 1 223 1.03E-60 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal ALX04_RS09535 93eda4d60e92395d21f3db0b9ecd3aa2 633 Gene3D G3DSA:3.60.20.10 1 222 3.1E-52 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal ALX04_RS09050 493e7ad97303669c7972b2add4c2ca73 660 SUPERFAMILY SSF55604 405 477 1.96E-18 T 28-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 ALX04_RS09050 493e7ad97303669c7972b2add4c2ca73 660 Gene3D G3DSA:2.70.70.10 500 659 1.8E-51 T 28-03-2018 ALX04_RS09050 493e7ad97303669c7972b2add4c2ca73 660 Gene3D G3DSA:3.30.1360.60 403 478 1.5E-24 T 28-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 ALX04_RS09050 493e7ad97303669c7972b2add4c2ca73 660 ProSitePatterns PS01035 PTS EIIB domains cysteine phosphorylation site signature. 418 435 - T 28-03-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 ALX04_RS09050 493e7ad97303669c7972b2add4c2ca73 660 SUPERFAMILY SSF51261 510 658 6.63E-50 T 28-03-2018 IPR011055 Duplicated hybrid motif ALX04_RS09050 493e7ad97303669c7972b2add4c2ca73 660 TIGRFAM TIGR01998 PTS-II-BC-nag: PTS system, N-acetylglucosamine-specific IIBC component 1 475 3.9E-201 T 28-03-2018 IPR010974 Phosphotransferase system, N-acetylglucosamine-specific IIBC component GO:0008982|GO:0009401|GO:0015572|GO:0016021|GO:0019866 ALX04_RS09050 493e7ad97303669c7972b2add4c2ca73 660 TIGRFAM TIGR00826 EIIB_glc: PTS system, glucose-like IIB component 371 465 8.1E-16 T 28-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 ALX04_RS09050 493e7ad97303669c7972b2add4c2ca73 660 Pfam PF02378 Phosphotransferase system, EIIC 10 312 4.6E-69 T 28-03-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 ALX04_RS09050 493e7ad97303669c7972b2add4c2ca73 660 ProSitePatterns PS00371 PTS EIIA domains phosphorylation site signature 1. 574 586 - T 28-03-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 ALX04_RS09050 493e7ad97303669c7972b2add4c2ca73 660 TIGRFAM TIGR00830 PTBA: PTS system, glucose subfamily, IIA component 514 632 4.1E-41 T 28-03-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 ALX04_RS09050 493e7ad97303669c7972b2add4c2ca73 660 Pfam PF00367 phosphotransferase system, EIIB 407 440 1.9E-12 T 28-03-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 ALX04_RS09050 493e7ad97303669c7972b2add4c2ca73 660 Pfam PF00358 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 511 634 6.9E-47 T 28-03-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 ALX04_RS02055 1dad9055e0d3a8a5d6e348ae7b8aa9c9 204 Pfam PF03358 NADPH-dependent FMN reductase 1 145 1.6E-37 T 28-03-2018 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 ALX04_RS02055 1dad9055e0d3a8a5d6e348ae7b8aa9c9 204 Gene3D G3DSA:3.40.50.360 1 179 3.7E-32 T 28-03-2018 IPR029039 Flavoprotein-like domain ALX04_RS02055 1dad9055e0d3a8a5d6e348ae7b8aa9c9 204 SUPERFAMILY SSF52218 1 172 1.14E-42 T 28-03-2018 IPR029039 Flavoprotein-like domain ALX04_RS13020 d701baef6e091edd1e05015220f6a2ed 287 PIRSF PIRSF001359 1 286 7.3E-107 T 28-03-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 ALX04_RS13020 d701baef6e091edd1e05015220f6a2ed 287 Pfam PF01116 Fructose-bisphosphate aldolase class-II 5 282 4.1E-91 T 28-03-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 ALX04_RS13020 d701baef6e091edd1e05015220f6a2ed 287 Gene3D G3DSA:3.20.20.70 1 284 5.3E-91 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 ALX04_RS13020 d701baef6e091edd1e05015220f6a2ed 287 TIGRFAM TIGR00167 cbbA: ketose-bisphosphate aldolase 1 282 1.5E-93 T 28-03-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 ALX04_RS13020 d701baef6e091edd1e05015220f6a2ed 287 ProSitePatterns PS00806 Fructose-bisphosphate aldolase class-II signature 2. 133 144 - T 28-03-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 ALX04_RS13020 d701baef6e091edd1e05015220f6a2ed 287 SUPERFAMILY SSF51569 1 283 7.87E-95 T 28-03-2018 ALX04_RS13020 d701baef6e091edd1e05015220f6a2ed 287 ProSitePatterns PS00602 Fructose-bisphosphate aldolase class-II signature 1. 74 87 - T 28-03-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 ALX04_RS13020 d701baef6e091edd1e05015220f6a2ed 287 TIGRFAM TIGR01859 fruc_bis_ald_: fructose-1,6-bisphosphate aldolase, class II 3 281 1.2E-112 T 28-03-2018 IPR011289 Fructose-1,6-bisphosphate aldolase, class 2 GO:0004332|GO:0006096|GO:0008270|GO:0030388 KEGG: 00010+4.1.2.13|KEGG: 00030+4.1.2.13|KEGG: 00051+4.1.2.13|KEGG: 00680+4.1.2.13|KEGG: 00710+4.1.2.13|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7385 ALX04_RS07515 962f497fdf1dd08cd059e30a24ac7196 599 Pfam PF01432 Peptidase family M3 339 543 2.5E-17 T 28-03-2018 IPR001567 Peptidase M3A/M3B catalytic domain GO:0004222|GO:0006508 ALX04_RS07515 962f497fdf1dd08cd059e30a24ac7196 599 Pfam PF08439 Oligopeptidase F 114 179 6.8E-9 T 28-03-2018 IPR013647 Oligopeptidase F, N-terminal domain ALX04_RS07515 962f497fdf1dd08cd059e30a24ac7196 599 SUPERFAMILY SSF55486 6 583 1.05E-88 T 28-03-2018 ALX04_RS07515 962f497fdf1dd08cd059e30a24ac7196 599 TIGRFAM TIGR02290 M3_fam_3: oligoendopeptidase, pepF/M3 family 6 594 6.4E-189 T 28-03-2018 IPR011977 Peptidase M3B, oligoendopeptidase-related clade 3 ALX04_RS01075 5ae301dfbc1354660d2a1b75466c42ac 193 SUPERFAMILY SSF51182 4 185 1.78E-71 T 28-03-2018 IPR011051 RmlC-like cupin domain ALX04_RS01075 5ae301dfbc1354660d2a1b75466c42ac 193 TIGRFAM TIGR01221 rmlC: dTDP-4-dehydrorhamnose 3,5-epimerase 5 182 5.6E-67 T 28-03-2018 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 ALX04_RS01075 5ae301dfbc1354660d2a1b75466c42ac 193 Gene3D G3DSA:2.60.120.10 2 189 9.2E-73 T 28-03-2018 IPR014710 RmlC-like jelly roll fold ALX04_RS01075 5ae301dfbc1354660d2a1b75466c42ac 193 ProDom PD001462 35-EPIMERASE DTDP-4-DEHYDRORHAMNOSE ISOMERASE RMLC EPIMERASE RELATED DTDP-6-DEOXY-D-GLUCOSE-35-EPIMERASE DTDP-4-KETO-6-DEOXY-D-GLUCOSE DTDP-4-KETO-6-DEOXYGLUCOSE-35-EPIMERASE DTDP-L-RHAMNOSE 5 174 1.0E-96 T 28-03-2018 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 ALX04_RS01075 5ae301dfbc1354660d2a1b75466c42ac 193 Pfam PF00908 dTDP-4-dehydrorhamnose 3,5-epimerase 9 181 2.6E-69 T 28-03-2018 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 ALX04_RS04390 a49448d396d821712a3f64248c5d4bc7 241 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 16 238 1.9E-28 T 28-03-2018 ALX04_RS04390 a49448d396d821712a3f64248c5d4bc7 241 SUPERFAMILY SSF51735 1 239 1.99E-40 T 28-03-2018 IPR016040 NAD(P)-binding domain ALX04_RS04390 a49448d396d821712a3f64248c5d4bc7 241 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 4.2E-15 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR ALX04_RS04390 a49448d396d821712a3f64248c5d4bc7 241 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 167 184 4.2E-15 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR ALX04_RS04390 a49448d396d821712a3f64248c5d4bc7 241 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 123 139 4.2E-15 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR ALX04_RS04390 a49448d396d821712a3f64248c5d4bc7 241 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 204 224 4.2E-15 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR ALX04_RS04390 a49448d396d821712a3f64248c5d4bc7 241 Gene3D G3DSA:3.40.50.720 1 241 1.9E-40 T 28-03-2018 ALX04_RS05485 8928bc5f91671e82641ec71b4a4f9268 932 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 57 68 - T 28-03-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 ALX04_RS05485 8928bc5f91671e82641ec71b4a4f9268 932 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 28 636 2.3E-203 T 28-03-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 ALX04_RS05485 8928bc5f91671e82641ec71b4a4f9268 932 Hamap MF_02002 Isoleucine--tRNA ligase [ileS]. 1 919 19.73 T 28-03-2018 IPR023585 Isoleucine-tRNA ligase, type 1 GO:0004822 KEGG: 00970+6.1.1.5|Reactome: R-HSA-379726 ALX04_RS05485 8928bc5f91671e82641ec71b4a4f9268 932 Gene3D G3DSA:1.10.730.10 636 806 4.4E-42 T 28-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 ALX04_RS05485 8928bc5f91671e82641ec71b4a4f9268 932 SUPERFAMILY SSF47323 647 919 5.79E-70 T 28-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 ALX04_RS05485 8928bc5f91671e82641ec71b4a4f9268 932 TIGRFAM TIGR00392 ileS: isoleucine--tRNA ligase 13 834 3.1E-281 T 28-03-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 ALX04_RS05485 8928bc5f91671e82641ec71b4a4f9268 932 Pfam PF08264 Anticodon-binding domain of tRNA 680 831 1.1E-28 T 28-03-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0000166|GO:0006418 ALX04_RS05485 8928bc5f91671e82641ec71b4a4f9268 932 SUPERFAMILY SSF52374 1 200 8.19E-148 T 28-03-2018 ALX04_RS05485 8928bc5f91671e82641ec71b4a4f9268 932 SUPERFAMILY SSF52374 396 643 8.19E-148 T 28-03-2018 ALX04_RS05485 8928bc5f91671e82641ec71b4a4f9268 932 Pfam PF06827 Zinc finger found in FPG and IleRS 888 915 6.0E-7 T 28-03-2018 IPR010663 Zinc finger, FPG/IleRS-type Reactome: R-HSA-379726 ALX04_RS05485 8928bc5f91671e82641ec71b4a4f9268 932 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 522 535 2.2E-29 T 28-03-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 ALX04_RS05485 8928bc5f91671e82641ec71b4a4f9268 932 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 50 61 2.2E-29 T 28-03-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 ALX04_RS05485 8928bc5f91671e82641ec71b4a4f9268 932 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 394 409 2.2E-29 T 28-03-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 ALX04_RS05485 8928bc5f91671e82641ec71b4a4f9268 932 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 228 251 2.2E-29 T 28-03-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 ALX04_RS05485 8928bc5f91671e82641ec71b4a4f9268 932 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 556 565 2.2E-29 T 28-03-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 ALX04_RS05485 8928bc5f91671e82641ec71b4a4f9268 932 Gene3D G3DSA:3.30.2320.20 807 886 4.4E-23 T 28-03-2018 ALX04_RS05485 8928bc5f91671e82641ec71b4a4f9268 932 Gene3D G3DSA:3.40.50.620 18 635 6.9E-130 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold ALX04_RS05485 8928bc5f91671e82641ec71b4a4f9268 932 SUPERFAMILY SSF50677 201 396 5.97E-52 T 28-03-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 ALX04_RS15000 be2f74eee2d655836c2caa6cb7c5ef5c 509 Pfam PF01966 HD domain 352 450 2.8E-5 T 28-03-2018 IPR006674 HD domain ALX04_RS15000 be2f74eee2d655836c2caa6cb7c5ef5c 509 Gene3D G3DSA:3.30.420.40 1 123 2.0E-17 T 28-03-2018 ALX04_RS15000 be2f74eee2d655836c2caa6cb7c5ef5c 509 Gene3D G3DSA:3.30.420.150 132 306 1.2E-12 T 28-03-2018 ALX04_RS15000 be2f74eee2d655836c2caa6cb7c5ef5c 509 SUPERFAMILY SSF109604 320 506 2.27E-42 T 28-03-2018 ALX04_RS15000 be2f74eee2d655836c2caa6cb7c5ef5c 509 SUPERFAMILY SSF53067 140 302 4.27E-6 T 28-03-2018 ALX04_RS15000 be2f74eee2d655836c2caa6cb7c5ef5c 509 SUPERFAMILY SSF53067 5 124 3.63E-16 T 28-03-2018 ALX04_RS15000 be2f74eee2d655836c2caa6cb7c5ef5c 509 Gene3D G3DSA:1.10.3210.10 310 490 9.5E-7 T 28-03-2018 ALX04_RS15000 be2f74eee2d655836c2caa6cb7c5ef5c 509 Pfam PF02541 Ppx/GppA phosphatase family 26 303 6.1E-12 T 28-03-2018 IPR003695 Ppx/GppA phosphatase KEGG: 00230+3.6.1.40 ALX04_RS08940 fa1bbb0d7df656c7a36b5a78f0ed096f 459 Pfam PF00939 Sodium:sulfate symporter transmembrane region 5 456 5.4E-34 T 28-03-2018 IPR001898 Solute carrier family 13 GO:0005215|GO:0006814|GO:0016020|GO:0055085 Reactome: R-HSA-433137 ALX04_RS02100 ab710c5fe392b399fd8cb60a4dba11e1 355 SUPERFAMILY SSF53927 4 141 6.73E-41 T 28-03-2018 IPR016193 Cytidine deaminase-like GO:0003824 ALX04_RS02100 ab710c5fe392b399fd8cb60a4dba11e1 355 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 4 99 5.8E-19 T 28-03-2018 IPR002125 Cytidine and deoxycytidylate deaminase domain ALX04_RS02100 ab710c5fe392b399fd8cb60a4dba11e1 355 Gene3D G3DSA:3.40.430.10 125 351 6.7E-48 T 28-03-2018 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 ALX04_RS02100 ab710c5fe392b399fd8cb60a4dba11e1 355 PIRSF PIRSF006769 1 354 1.4E-95 T 28-03-2018 IPR004794 Riboflavin biosynthesis protein RibD GO:0008835|GO:0009231|GO:0055114 KEGG: 00040+1.1.1.19|KEGG: 00053+1.1.1.19|KEGG: 00740+3.5.4.26+1.1.1.193|MetaCyc: PWY-5525 ALX04_RS02100 ab710c5fe392b399fd8cb60a4dba11e1 355 Pfam PF01872 RibD C-terminal domain 147 334 3.6E-31 T 28-03-2018 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 ALX04_RS02100 ab710c5fe392b399fd8cb60a4dba11e1 355 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 49 88 - T 28-03-2018 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 ALX04_RS02100 ab710c5fe392b399fd8cb60a4dba11e1 355 TIGRFAM TIGR00326 eubact_ribD: riboflavin biosynthesis protein RibD 6 345 5.4E-84 T 28-03-2018 IPR004794 Riboflavin biosynthesis protein RibD GO:0008835|GO:0009231|GO:0055114 KEGG: 00040+1.1.1.19|KEGG: 00053+1.1.1.19|KEGG: 00740+3.5.4.26+1.1.1.193|MetaCyc: PWY-5525 ALX04_RS02100 ab710c5fe392b399fd8cb60a4dba11e1 355 SUPERFAMILY SSF53597 145 344 1.45E-38 T 28-03-2018 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 ALX04_RS02100 ab710c5fe392b399fd8cb60a4dba11e1 355 Gene3D G3DSA:3.40.140.10 2 124 2.7E-30 T 28-03-2018 ALX04_RS03430 1879bbb47e8f08c9b91dcdb6d4d6a134 250 Pfam PF00326 Prolyl oligopeptidase family 93 236 1.4E-11 T 28-03-2018 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 ALX04_RS03430 1879bbb47e8f08c9b91dcdb6d4d6a134 250 Gene3D G3DSA:3.40.50.1820 12 247 5.3E-28 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold ALX04_RS03430 1879bbb47e8f08c9b91dcdb6d4d6a134 250 SUPERFAMILY SSF53474 19 249 3.38E-33 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold ALX04_RS04080 2356eb5813242a2186ac43caad5a8ed9 758 Gene3D G3DSA:2.70.150.10 2 192 2.6E-31 T 28-03-2018 ALX04_RS04080 2356eb5813242a2186ac43caad5a8ed9 758 Pfam PF00122 E1-E2 ATPase 93 270 1.8E-38 T 28-03-2018 ALX04_RS04080 2356eb5813242a2186ac43caad5a8ed9 758 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 513 529 1.4E-17 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 ALX04_RS04080 2356eb5813242a2186ac43caad5a8ed9 758 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 544 569 1.4E-17 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 ALX04_RS04080 2356eb5813242a2186ac43caad5a8ed9 758 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 674 695 1.4E-17 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 ALX04_RS04080 2356eb5813242a2186ac43caad5a8ed9 758 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 485 501 1.4E-17 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 ALX04_RS04080 2356eb5813242a2186ac43caad5a8ed9 758 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 292 298 - T 28-03-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 ALX04_RS04080 2356eb5813242a2186ac43caad5a8ed9 758 Pfam PF00702 haloacid dehalogenase-like hydrolase 287 525 2.3E-28 T 28-03-2018 ALX04_RS04080 2356eb5813242a2186ac43caad5a8ed9 758 Gene3D G3DSA:1.20.1110.10 539 758 8.4E-10 T 28-03-2018 ALX04_RS04080 2356eb5813242a2186ac43caad5a8ed9 758 SUPERFAMILY SSF56784 287 560 2.09E-38 T 28-03-2018 IPR023214 HAD-like domain ALX04_RS04080 2356eb5813242a2186ac43caad5a8ed9 758 SUPERFAMILY SSF81665 5 95 1.83E-48 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 ALX04_RS04080 2356eb5813242a2186ac43caad5a8ed9 758 SUPERFAMILY SSF81665 562 743 1.83E-48 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 ALX04_RS04080 2356eb5813242a2186ac43caad5a8ed9 758 SUPERFAMILY SSF81665 191 284 1.83E-48 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 ALX04_RS04080 2356eb5813242a2186ac43caad5a8ed9 758 SUPERFAMILY SSF81653 95 191 7.19E-24 T 28-03-2018 IPR008250 P-type ATPase, A domain Reactome: R-HSA-936837 ALX04_RS04080 2356eb5813242a2186ac43caad5a8ed9 758 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 419 430 7.7E-30 T 28-03-2018 ALX04_RS04080 2356eb5813242a2186ac43caad5a8ed9 758 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 141 155 7.7E-30 T 28-03-2018 ALX04_RS04080 2356eb5813242a2186ac43caad5a8ed9 758 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 513 532 7.7E-30 T 28-03-2018 ALX04_RS04080 2356eb5813242a2186ac43caad5a8ed9 758 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 441 451 7.7E-30 T 28-03-2018 ALX04_RS04080 2356eb5813242a2186ac43caad5a8ed9 758 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 290 304 7.7E-30 T 28-03-2018 ALX04_RS04080 2356eb5813242a2186ac43caad5a8ed9 758 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 536 548 7.7E-30 T 28-03-2018 ALX04_RS04080 2356eb5813242a2186ac43caad5a8ed9 758 Gene3D G3DSA:3.40.50.1000 272 538 1.3E-34 T 28-03-2018 IPR023214 HAD-like domain ALX04_RS04080 2356eb5813242a2186ac43caad5a8ed9 758 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 486 592 2.7E-23 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 ALX04_RS04080 2356eb5813242a2186ac43caad5a8ed9 758 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 63 311 3.9E-33 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 ALX04_RS00130 0afa98914d2e18bec2bf620a7adf61d5 338 Pfam PF07859 alpha/beta hydrolase fold 102 317 1.2E-51 T 28-03-2018 IPR013094 Alpha/beta hydrolase fold-3 GO:0008152|GO:0016787 ALX04_RS00130 0afa98914d2e18bec2bf620a7adf61d5 338 SUPERFAMILY SSF53474 71 337 7.88E-44 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold ALX04_RS00130 0afa98914d2e18bec2bf620a7adf61d5 338 Gene3D G3DSA:3.40.50.1820 29 337 5.3E-34 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold ALX04_RS08780 d01ed45893cfbe04f3effb8c4ae9eff8 314 SMART SM00892 95 264 8.5E-16 T 28-03-2018 IPR001604 DNA/RNA non-specific endonuclease GO:0003676|GO:0016787|GO:0046872 ALX04_RS08780 d01ed45893cfbe04f3effb8c4ae9eff8 314 Pfam PF13930 DNA/RNA non-specific endonuclease 95 229 1.6E-16 T 28-03-2018 ALX04_RS15850 de8b85fd3ddbca2346bb37a598ed2b31 238 SUPERFAMILY SSF54106 28 71 1.2E-9 T 28-03-2018 IPR018392 LysM domain ALX04_RS15850 de8b85fd3ddbca2346bb37a598ed2b31 238 SMART SM00257 28 72 2.0E-14 T 28-03-2018 IPR018392 LysM domain ALX04_RS15850 de8b85fd3ddbca2346bb37a598ed2b31 238 Gene3D G3DSA:3.10.350.10 23 77 2.1E-14 T 28-03-2018 ALX04_RS15850 de8b85fd3ddbca2346bb37a598ed2b31 238 Pfam PF01476 LysM domain 29 70 8.4E-13 T 28-03-2018 IPR018392 LysM domain ALX04_RS13755 0c541ef9e6c83cea2e74c59ad4dc5ea5 1020 Pfam PF02787 Carbamoyl-phosphate synthetase large chain, oligomerisation domain 424 537 2.2E-27 T 28-03-2018 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 ALX04_RS13755 0c541ef9e6c83cea2e74c59ad4dc5ea5 1020 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 164 178 - T 28-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 ALX04_RS13755 0c541ef9e6c83cea2e74c59ad4dc5ea5 1020 SUPERFAMILY SSF48108 395 538 2.22E-31 T 28-03-2018 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 ALX04_RS13755 0c541ef9e6c83cea2e74c59ad4dc5ea5 1020 Gene3D G3DSA:3.30.470.20 746 970 1.7E-38 T 28-03-2018 ALX04_RS13755 0c541ef9e6c83cea2e74c59ad4dc5ea5 1020 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 700 714 - T 28-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 ALX04_RS13755 0c541ef9e6c83cea2e74c59ad4dc5ea5 1020 SUPERFAMILY SSF56059 664 924 4.24E-86 T 28-03-2018 ALX04_RS13755 0c541ef9e6c83cea2e74c59ad4dc5ea5 1020 SUPERFAMILY SSF52440 550 666 2.3E-45 T 28-03-2018 IPR016185 Pre-ATP-grasp domain ALX04_RS13755 0c541ef9e6c83cea2e74c59ad4dc5ea5 1020 Gene3D G3DSA:3.30.470.20 120 401 7.4E-64 T 28-03-2018 ALX04_RS13755 0c541ef9e6c83cea2e74c59ad4dc5ea5 1020 SUPERFAMILY SSF56059 128 399 3.71E-102 T 28-03-2018 ALX04_RS13755 0c541ef9e6c83cea2e74c59ad4dc5ea5 1020 Gene3D G3DSA:3.40.50.20 548 645 3.4E-41 T 28-03-2018 ALX04_RS13755 0c541ef9e6c83cea2e74c59ad4dc5ea5 1020 Gene3D G3DSA:3.40.50.20 4 111 5.2E-33 T 28-03-2018 ALX04_RS13755 0c541ef9e6c83cea2e74c59ad4dc5ea5 1020 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 296 303 - T 28-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 ALX04_RS13755 0c541ef9e6c83cea2e74c59ad4dc5ea5 1020 SMART SM01096 421 538 1.1E-37 T 28-03-2018 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 ALX04_RS13755 0c541ef9e6c83cea2e74c59ad4dc5ea5 1020 Hamap MF_01210_B Carbamoyl-phosphate synthase large chain [carB]. 1 1020 11.994 T 28-03-2018 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 ALX04_RS13755 0c541ef9e6c83cea2e74c59ad4dc5ea5 1020 TIGRFAM TIGR01369 CPSaseII_lrg: carbamoyl-phosphate synthase, large subunit 2 967 0.0 T 28-03-2018 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 ALX04_RS13755 0c541ef9e6c83cea2e74c59ad4dc5ea5 1020 Gene3D G3DSA:3.30.1490.20 646 745 7.4E-15 T 28-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 ALX04_RS13755 0c541ef9e6c83cea2e74c59ad4dc5ea5 1020 Gene3D G3DSA:1.10.1030.10 402 545 1.1E-30 T 28-03-2018 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 ALX04_RS13755 0c541ef9e6c83cea2e74c59ad4dc5ea5 1020 SUPERFAMILY SSF52440 1 127 4.89E-43 T 28-03-2018 IPR016185 Pre-ATP-grasp domain ALX04_RS13755 0c541ef9e6c83cea2e74c59ad4dc5ea5 1020 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 378 396 6.4E-60 T 28-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 ALX04_RS13755 0c541ef9e6c83cea2e74c59ad4dc5ea5 1020 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 48 58 6.4E-60 T 28-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 ALX04_RS13755 0c541ef9e6c83cea2e74c59ad4dc5ea5 1020 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 204 223 6.4E-60 T 28-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 ALX04_RS13755 0c541ef9e6c83cea2e74c59ad4dc5ea5 1020 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 168 180 6.4E-60 T 28-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 ALX04_RS13755 0c541ef9e6c83cea2e74c59ad4dc5ea5 1020 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 296 325 6.4E-60 T 28-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 ALX04_RS13755 0c541ef9e6c83cea2e74c59ad4dc5ea5 1020 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 19 33 6.4E-60 T 28-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 ALX04_RS13755 0c541ef9e6c83cea2e74c59ad4dc5ea5 1020 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 239 256 6.4E-60 T 28-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 ALX04_RS13755 0c541ef9e6c83cea2e74c59ad4dc5ea5 1020 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 128 333 1.4E-72 T 28-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 ALX04_RS13755 0c541ef9e6c83cea2e74c59ad4dc5ea5 1020 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 664 863 1.8E-32 T 28-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 ALX04_RS04020 54425facfd6ac5170e8f40c69acf46e1 340 Gene3D G3DSA:3.40.1390.30 1 111 6.7E-37 T 28-03-2018 ALX04_RS04020 54425facfd6ac5170e8f40c69acf46e1 340 SUPERFAMILY SSF102705 1 339 5.49E-93 T 28-03-2018 IPR002678 GTP cyclohydrolase 1 type 2/Nif3 ALX04_RS04020 54425facfd6ac5170e8f40c69acf46e1 340 PIRSF PIRSF037489 185 340 1.4E-47 T 28-03-2018 IPR017221 GTP cyclohydrolase 1 type 2//Nif3, bacteria ALX04_RS04020 54425facfd6ac5170e8f40c69acf46e1 340 PIRSF PIRSF037489 1 173 6.2E-61 T 28-03-2018 IPR017221 GTP cyclohydrolase 1 type 2//Nif3, bacteria ALX04_RS04020 54425facfd6ac5170e8f40c69acf46e1 340 TIGRFAM TIGR00486 YbgI_SA1388: dinuclear metal center protein, YbgI/SA1388 family 1 333 8.4E-61 T 28-03-2018 IPR002678 GTP cyclohydrolase 1 type 2/Nif3 ALX04_RS04020 54425facfd6ac5170e8f40c69acf46e1 340 Gene3D G3DSA:3.40.1390.30 112 174 3.8E-6 T 28-03-2018 ALX04_RS04020 54425facfd6ac5170e8f40c69acf46e1 340 Gene3D G3DSA:3.40.1390.30 177 299 7.2E-27 T 28-03-2018 ALX04_RS04020 54425facfd6ac5170e8f40c69acf46e1 340 Pfam PF01784 NIF3 (NGG1p interacting factor 3) 5 317 2.2E-72 T 28-03-2018 IPR002678 GTP cyclohydrolase 1 type 2/Nif3 ALX04_RS12790 9e9fb4aef2519e6ca5b43bd8d7c0a43e 466 Gene3D G3DSA:1.20.1250.20 249 465 2.9E-31 T 28-03-2018 ALX04_RS12790 9e9fb4aef2519e6ca5b43bd8d7c0a43e 466 Pfam PF07690 Major Facilitator Superfamily 16 406 2.8E-47 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 ALX04_RS12790 9e9fb4aef2519e6ca5b43bd8d7c0a43e 466 Gene3D G3DSA:1.20.1250.20 2 197 2.4E-26 T 28-03-2018 ALX04_RS12790 9e9fb4aef2519e6ca5b43bd8d7c0a43e 466 SUPERFAMILY SSF103473 6 199 6.54E-58 T 28-03-2018 IPR020846 Major facilitator superfamily domain ALX04_RS12790 9e9fb4aef2519e6ca5b43bd8d7c0a43e 466 SUPERFAMILY SSF103473 246 464 6.54E-58 T 28-03-2018 IPR020846 Major facilitator superfamily domain ALX04_RS12790 9e9fb4aef2519e6ca5b43bd8d7c0a43e 466 PRINTS PR01036 Tetracycline resistance protein TetB signature 134 158 3.1E-5 T 28-03-2018 ALX04_RS12790 9e9fb4aef2519e6ca5b43bd8d7c0a43e 466 PRINTS PR01036 Tetracycline resistance protein TetB signature 13 37 3.1E-5 T 28-03-2018 ALX04_RS12790 9e9fb4aef2519e6ca5b43bd8d7c0a43e 466 PRINTS PR01036 Tetracycline resistance protein TetB signature 104 124 3.1E-5 T 28-03-2018 ALX04_RS11035 65f1bb62312614851c80d0703d194fdf 652 TIGRFAM TIGR00792 gph: sugar (Glycoside-Pentoside-Hexuronide) transporter 16 471 6.5E-145 T 28-03-2018 IPR001927 Sodium:galactoside symporter GO:0005215|GO:0006814|GO:0016020 ALX04_RS11035 65f1bb62312614851c80d0703d194fdf 652 ProSitePatterns PS00872 Sodium:galactoside symporter family signature. 76 101 - T 28-03-2018 IPR018043 Sodium:galactoside symporter, conserved site GO:0005215|GO:0006814|GO:0016020 ALX04_RS11035 65f1bb62312614851c80d0703d194fdf 652 SUPERFAMILY SSF103473 18 461 9.59E-32 T 28-03-2018 IPR020846 Major facilitator superfamily domain ALX04_RS11035 65f1bb62312614851c80d0703d194fdf 652 Gene3D G3DSA:2.70.70.10 484 645 1.2E-49 T 28-03-2018 ALX04_RS11035 65f1bb62312614851c80d0703d194fdf 652 Gene3D G3DSA:1.20.1250.20 243 466 1.0E-17 T 28-03-2018 ALX04_RS11035 65f1bb62312614851c80d0703d194fdf 652 Gene3D G3DSA:1.20.1250.20 12 241 9.5E-11 T 28-03-2018 ALX04_RS11035 65f1bb62312614851c80d0703d194fdf 652 TIGRFAM TIGR00830 PTBA: PTS system, glucose subfamily, IIA component 500 617 4.5E-43 T 28-03-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 ALX04_RS11035 65f1bb62312614851c80d0703d194fdf 652 Pfam PF00358 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 499 620 6.1E-44 T 28-03-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 ALX04_RS11035 65f1bb62312614851c80d0703d194fdf 652 Pfam PF13347 MFS/sugar transport protein 19 458 6.1E-87 T 28-03-2018 ALX04_RS11035 65f1bb62312614851c80d0703d194fdf 652 SUPERFAMILY SSF51261 493 631 6.1E-47 T 28-03-2018 IPR011055 Duplicated hybrid motif ALX04_RS11400 156300597f993236f84457ad08869217 366 ProSitePatterns PS00557 FMN-dependent alpha-hydroxy acid dehydrogenases active site. 262 268 - T 28-03-2018 IPR008259 FMN-dependent alpha-hydroxy acid dehydrogenase, active site GO:0016491|GO:0055114 ALX04_RS11400 156300597f993236f84457ad08869217 366 SUPERFAMILY SSF51395 18 363 2.44E-89 T 28-03-2018 ALX04_RS11400 156300597f993236f84457ad08869217 366 Pfam PF01070 FMN-dependent dehydrogenase 28 363 7.0E-112 T 28-03-2018 IPR000262 FMN-dependent dehydrogenase GO:0016491 ALX04_RS11400 156300597f993236f84457ad08869217 366 Gene3D G3DSA:3.20.20.70 17 366 1.6E-96 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 ALX04_RS11400 156300597f993236f84457ad08869217 366 PIRSF PIRSF000138 1 366 8.7E-130 T 28-03-2018 IPR012133 Alpha-hydroxy acid dehydrogenase, FMN-dependent GO:0010181|GO:0016491|GO:0055114 ALX04_RS05535 94d4e76941fd195dcec34033de8657b0 321 Hamap MF_00038 Phospho-N-acetylmuramoyl-pentapeptide-transferase [mraY]. 5 321 22.718 T 28-03-2018 IPR003524 Phospho-N-acetylmuramoyl-pentapeptide transferase GO:0008963|GO:0016020 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 ALX04_RS05535 94d4e76941fd195dcec34033de8657b0 321 ProSitePatterns PS01347 MraY family signature 1. 48 60 - T 28-03-2018 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 ALX04_RS05535 94d4e76941fd195dcec34033de8657b0 321 Pfam PF10555 Phospho-N-acetylmuramoyl-pentapeptide-transferase signature 1 48 60 8.1E-6 T 28-03-2018 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 ALX04_RS05535 94d4e76941fd195dcec34033de8657b0 321 ProSitePatterns PS01348 MraY family signature 2. 167 178 - T 28-03-2018 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 ALX04_RS05535 94d4e76941fd195dcec34033de8657b0 321 TIGRFAM TIGR00445 mraY: phospho-N-acetylmuramoyl-pentapeptide-transferase 20 320 4.9E-99 T 28-03-2018 IPR003524 Phospho-N-acetylmuramoyl-pentapeptide transferase GO:0008963|GO:0016020 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 ALX04_RS05535 94d4e76941fd195dcec34033de8657b0 321 Pfam PF00953 Glycosyl transferase family 4 82 247 2.1E-40 T 28-03-2018 IPR000715 Glycosyl transferase, family 4 GO:0008963|GO:0016021 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193 ALX04_RS15095 fa4f5339784b7c6c26e15017b8673336 193 Gene3D G3DSA:3.30.63.10 48 73 1.1E-12 T 28-03-2018 ALX04_RS15095 fa4f5339784b7c6c26e15017b8673336 193 Gene3D G3DSA:3.40.50.300 74 185 1.4E-12 T 28-03-2018 ALX04_RS15095 fa4f5339784b7c6c26e15017b8673336 193 SUPERFAMILY SSF52540 3 186 8.72E-37 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase ALX04_RS15095 fa4f5339784b7c6c26e15017b8673336 193 SMART SM00072 3 185 2.5E-10 T 28-03-2018 IPR008145 Guanylate kinase/L-type calcium channel beta subunit ALX04_RS15095 fa4f5339784b7c6c26e15017b8673336 193 Pfam PF00625 Guanylate kinase 4 183 1.3E-17 T 28-03-2018 IPR008145 Guanylate kinase/L-type calcium channel beta subunit ALX04_RS15095 fa4f5339784b7c6c26e15017b8673336 193 Gene3D G3DSA:3.40.50.300 4 47 3.7E-7 T 28-03-2018 ALX04_RS02780 b33ae16199541ba4db033a9c540e8b15 206 ProSitePatterns PS00856 Guanylate kinase-like signature. 40 57 - T 28-03-2018 IPR020590 Guanylate kinase, conserved site KEGG: 00230+2.7.4.8|MetaCyc: PWY-7221 ALX04_RS02780 b33ae16199541ba4db033a9c540e8b15 206 TIGRFAM TIGR03263 guanyl_kin: guanylate kinase 5 184 6.5E-73 T 28-03-2018 IPR017665 Guanylate kinase GO:0004385|GO:0006163 KEGG: 00230+2.7.4.8|MetaCyc: PWY-7221|Reactome: R-HSA-2161541|Reactome: R-HSA-499943 ALX04_RS02780 b33ae16199541ba4db033a9c540e8b15 206 SUPERFAMILY SSF52540 4 190 4.65E-67 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase ALX04_RS02780 b33ae16199541ba4db033a9c540e8b15 206 Gene3D G3DSA:3.40.50.300 1 50 1.7E-7 T 28-03-2018 ALX04_RS02780 b33ae16199541ba4db033a9c540e8b15 206 Pfam PF00625 Guanylate kinase 7 185 1.1E-51 T 28-03-2018 IPR008145 Guanylate kinase/L-type calcium channel beta subunit ALX04_RS02780 b33ae16199541ba4db033a9c540e8b15 206 Hamap MF_00328 Guanylate kinase [gmk]. 3 187 35.906 T 28-03-2018 IPR017665 Guanylate kinase GO:0004385|GO:0006163 KEGG: 00230+2.7.4.8|MetaCyc: PWY-7221|Reactome: R-HSA-2161541|Reactome: R-HSA-499943 ALX04_RS02780 b33ae16199541ba4db033a9c540e8b15 206 Gene3D G3DSA:3.40.50.300 82 188 5.6E-29 T 28-03-2018 ALX04_RS02780 b33ae16199541ba4db033a9c540e8b15 206 Gene3D G3DSA:3.30.63.10 51 81 7.8E-26 T 28-03-2018 ALX04_RS02780 b33ae16199541ba4db033a9c540e8b15 206 SMART SM00072 4 187 3.4E-67 T 28-03-2018 IPR008145 Guanylate kinase/L-type calcium channel beta subunit ALX04_RS09410 8703ef5c911c16ff88cd3eb2d269fab8 373 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 30 122 3.4E-22 T 28-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 ALX04_RS09410 8703ef5c911c16ff88cd3eb2d269fab8 373 Gene3D G3DSA:3.90.180.10 3 181 1.2E-40 T 28-03-2018 ALX04_RS09410 8703ef5c911c16ff88cd3eb2d269fab8 373 SUPERFAMILY SSF51735 158 330 5.38E-44 T 28-03-2018 IPR016040 NAD(P)-binding domain ALX04_RS09410 8703ef5c911c16ff88cd3eb2d269fab8 373 SMART SM00829 10 363 7.3E-5 T 28-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 ALX04_RS09410 8703ef5c911c16ff88cd3eb2d269fab8 373 Gene3D G3DSA:3.40.50.10730 182 359 3.2E-35 T 28-03-2018 ALX04_RS09410 8703ef5c911c16ff88cd3eb2d269fab8 373 Pfam PF00107 Zinc-binding dehydrogenase 196 313 2.4E-28 T 28-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 ALX04_RS09410 8703ef5c911c16ff88cd3eb2d269fab8 373 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 61 75 - T 28-03-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 ALX04_RS09410 8703ef5c911c16ff88cd3eb2d269fab8 373 SUPERFAMILY SSF50129 1 192 3.8E-56 T 28-03-2018 IPR011032 GroES-like ALX04_RS02155 a59e0df8ca0d4660f6fcde9a36444ab2 213 Pfam PF00027 Cyclic nucleotide-binding domain 33 118 1.3E-13 T 28-03-2018 IPR000595 Cyclic nucleotide-binding domain ALX04_RS02155 a59e0df8ca0d4660f6fcde9a36444ab2 213 Gene3D G3DSA:1.10.10.10 141 213 1.6E-14 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS02155 a59e0df8ca0d4660f6fcde9a36444ab2 213 PRINTS PR00034 CRP bacterial regulatory protein HTH signature 172 188 3.7E-6 T 28-03-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 ALX04_RS02155 a59e0df8ca0d4660f6fcde9a36444ab2 213 PRINTS PR00034 CRP bacterial regulatory protein HTH signature 188 203 3.7E-6 T 28-03-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 ALX04_RS02155 a59e0df8ca0d4660f6fcde9a36444ab2 213 SMART SM00419 166 212 1.1E-8 T 28-03-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 ALX04_RS02155 a59e0df8ca0d4660f6fcde9a36444ab2 213 SMART SM00100 13 132 1.1E-6 T 28-03-2018 IPR000595 Cyclic nucleotide-binding domain ALX04_RS02155 a59e0df8ca0d4660f6fcde9a36444ab2 213 Gene3D G3DSA:2.60.120.10 1 140 1.0E-19 T 28-03-2018 IPR014710 RmlC-like jelly roll fold ALX04_RS02155 a59e0df8ca0d4660f6fcde9a36444ab2 213 SUPERFAMILY SSF51206 6 139 3.27E-24 T 28-03-2018 IPR018490 Cyclic nucleotide-binding-like ALX04_RS02155 a59e0df8ca0d4660f6fcde9a36444ab2 213 Pfam PF13545 Crp-like helix-turn-helix domain 152 212 1.8E-12 T 28-03-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 ALX04_RS02155 a59e0df8ca0d4660f6fcde9a36444ab2 213 SUPERFAMILY SSF46785 149 212 2.33E-12 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS01370 4ab2772ca9cc8025d43417088f2adaf3 309 SUPERFAMILY SSF161098 92 286 3.71E-14 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 ALX04_RS01370 4ab2772ca9cc8025d43417088f2adaf3 309 Gene3D G3DSA:1.10.3720.10 1 292 7.6E-34 T 28-03-2018 ALX04_RS01370 4ab2772ca9cc8025d43417088f2adaf3 309 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 108 303 4.8E-40 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 ALX04_RS08170 2274961d7b8c2e7ed16310b0a884357b 235 Pfam PF07702 UTRA domain 88 218 5.9E-21 T 28-03-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 ALX04_RS08170 2274961d7b8c2e7ed16310b0a884357b 235 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 36 52 4.0E-7 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 ALX04_RS08170 2274961d7b8c2e7ed16310b0a884357b 235 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 22 36 4.0E-7 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 ALX04_RS08170 2274961d7b8c2e7ed16310b0a884357b 235 Pfam PF00392 Bacterial regulatory proteins, gntR family 2 62 1.2E-11 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 ALX04_RS08170 2274961d7b8c2e7ed16310b0a884357b 235 Gene3D G3DSA:3.40.1410.10 82 228 7.5E-22 T 28-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain ALX04_RS08170 2274961d7b8c2e7ed16310b0a884357b 235 SUPERFAMILY SSF46785 2 72 6.81E-14 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS08170 2274961d7b8c2e7ed16310b0a884357b 235 Gene3D G3DSA:1.10.10.10 1 64 8.2E-14 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS08170 2274961d7b8c2e7ed16310b0a884357b 235 SMART SM00345 5 62 1.1E-11 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 ALX04_RS08170 2274961d7b8c2e7ed16310b0a884357b 235 SUPERFAMILY SSF64288 50 223 7.38E-30 T 28-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain ALX04_RS08170 2274961d7b8c2e7ed16310b0a884357b 235 SMART SM00866 85 224 4.4E-19 T 28-03-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 ALX04_RS03400 d03d688907aa3caac167b4523629c1ba 189 Gene3D G3DSA:3.40.50.450 1 180 4.8E-31 T 28-03-2018 ALX04_RS03400 d03d688907aa3caac167b4523629c1ba 189 Pfam PF06908 Protein of unknown function (DUF1273) 4 171 2.4E-68 T 28-03-2018 IPR010697 Protein of unknown function DUF1273 ALX04_RS03400 d03d688907aa3caac167b4523629c1ba 189 SUPERFAMILY SSF102405 1 177 3.39E-63 T 28-03-2018 ALX04_RS03400 d03d688907aa3caac167b4523629c1ba 189 Hamap MF_01575 UPF0398 protein . 1 177 35.915 T 28-03-2018 IPR010697 Protein of unknown function DUF1273 ALX04_RS03400 d03d688907aa3caac167b4523629c1ba 189 PIRSF PIRSF021290 1 179 1.8E-69 T 28-03-2018 IPR010697 Protein of unknown function DUF1273 ALX04_RS15395 7bb78d3fd346a5c4bd56552d2eb6b59c 181 SUPERFAMILY SSF116734 7 167 4.09E-21 T 28-03-2018 ALX04_RS15395 7bb78d3fd346a5c4bd56552d2eb6b59c 181 Gene3D G3DSA:3.90.220.20 3 165 6.0E-21 T 28-03-2018 ALX04_RS15395 7bb78d3fd346a5c4bd56552d2eb6b59c 181 Pfam PF01420 Type I restriction modification DNA specificity domain 56 169 1.8E-7 T 28-03-2018 IPR000055 Restriction endonuclease, type I, HsdS GO:0003677|GO:0006304 ALX04_RS03230 f41a22a0a9141983ecba32d0dd49b656 441 Pfam PF02784 Pyridoxal-dependent decarboxylase, pyridoxal binding domain 41 298 5.1E-58 T 28-03-2018 IPR022644 Orn/DAP/Arg decarboxylase 2, N-terminal GO:0003824 ALX04_RS03230 f41a22a0a9141983ecba32d0dd49b656 441 Gene3D G3DSA:3.20.20.10 40 287 5.7E-57 T 28-03-2018 IPR029066 PLP-binding barrel ALX04_RS03230 f41a22a0a9141983ecba32d0dd49b656 441 Pfam PF00278 Pyridoxal-dependent decarboxylase, C-terminal sheet domain 35 389 2.0E-15 T 28-03-2018 IPR022643 Orn/DAP/Arg decarboxylase 2, C-terminal GO:0003824 ALX04_RS03230 f41a22a0a9141983ecba32d0dd49b656 441 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 64 82 2.6E-15 T 28-03-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 ALX04_RS03230 f41a22a0a9141983ecba32d0dd49b656 441 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 389 402 2.6E-15 T 28-03-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 ALX04_RS03230 f41a22a0a9141983ecba32d0dd49b656 441 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 84 96 2.6E-15 T 28-03-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 ALX04_RS03230 f41a22a0a9141983ecba32d0dd49b656 441 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 199 212 2.6E-15 T 28-03-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 ALX04_RS03230 f41a22a0a9141983ecba32d0dd49b656 441 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 288 307 2.6E-15 T 28-03-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 ALX04_RS03230 f41a22a0a9141983ecba32d0dd49b656 441 SUPERFAMILY SSF51419 31 300 4.65E-74 T 28-03-2018 IPR029066 PLP-binding barrel ALX04_RS03230 f41a22a0a9141983ecba32d0dd49b656 441 SUPERFAMILY SSF50621 274 432 1.3E-49 T 28-03-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 ALX04_RS03230 f41a22a0a9141983ecba32d0dd49b656 441 PRINTS PR01181 Diaminopimelate decarboxylase signature 171 180 7.4E-24 T 28-03-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 ALX04_RS03230 f41a22a0a9141983ecba32d0dd49b656 441 PRINTS PR01181 Diaminopimelate decarboxylase signature 399 421 7.4E-24 T 28-03-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 ALX04_RS03230 f41a22a0a9141983ecba32d0dd49b656 441 PRINTS PR01181 Diaminopimelate decarboxylase signature 317 335 7.4E-24 T 28-03-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 ALX04_RS03230 f41a22a0a9141983ecba32d0dd49b656 441 PRINTS PR01181 Diaminopimelate decarboxylase signature 82 99 7.4E-24 T 28-03-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 ALX04_RS03230 f41a22a0a9141983ecba32d0dd49b656 441 Hamap MF_02120 Diaminopimelate decarboxylase [lysA]. 20 432 37.492 T 28-03-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 ALX04_RS03230 f41a22a0a9141983ecba32d0dd49b656 441 Gene3D G3DSA:2.40.37.10 288 435 2.3E-38 T 28-03-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 ALX04_RS03230 f41a22a0a9141983ecba32d0dd49b656 441 TIGRFAM TIGR01048 lysA: diaminopimelate decarboxylase 12 431 6.3E-140 T 28-03-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 ALX04_RS04010 e64135893c626f5b8ba2ec04d80445fd 867 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 205 338 4.5E-15 T 28-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 ALX04_RS04010 e64135893c626f5b8ba2ec04d80445fd 867 SUPERFAMILY SSF52540 161 547 4.61E-96 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase ALX04_RS04010 e64135893c626f5b8ba2ec04d80445fd 867 Pfam PF07724 AAA domain (Cdc48 subfamily) 598 764 1.6E-55 T 28-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 ALX04_RS04010 e64135893c626f5b8ba2ec04d80445fd 867 Gene3D G3DSA:3.40.50.300 159 344 3.2E-26 T 28-03-2018 ALX04_RS04010 e64135893c626f5b8ba2ec04d80445fd 867 SUPERFAMILY SSF52540 548 859 1.07E-80 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase ALX04_RS04010 e64135893c626f5b8ba2ec04d80445fd 867 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 772 849 7.6E-26 T 28-03-2018 IPR019489 Clp ATPase, C-terminal ALX04_RS04010 e64135893c626f5b8ba2ec04d80445fd 867 ProSitePatterns PS00871 Chaperonins clpA/B signature 2. 633 651 - T 28-03-2018 IPR028299 ClpA/B, conserved site 2 ALX04_RS04010 e64135893c626f5b8ba2ec04d80445fd 867 SMART SM01086 770 859 4.2E-35 T 28-03-2018 IPR019489 Clp ATPase, C-terminal ALX04_RS04010 e64135893c626f5b8ba2ec04d80445fd 867 TIGRFAM TIGR03346 chaperone_ClpB: ATP-dependent chaperone protein ClpB 6 859 0.0 T 28-03-2018 IPR017730 Chaperonin ClpB GO:0005737|GO:0009408|GO:0016485 ALX04_RS04010 e64135893c626f5b8ba2ec04d80445fd 867 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 17 67 9.3E-10 T 28-03-2018 IPR004176 Clp, N-terminal GO:0019538 ALX04_RS04010 e64135893c626f5b8ba2ec04d80445fd 867 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 95 147 1.8E-6 T 28-03-2018 IPR004176 Clp, N-terminal GO:0019538 ALX04_RS04010 e64135893c626f5b8ba2ec04d80445fd 867 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 648 666 1.2E-42 T 28-03-2018 IPR001270 ClpA/B family GO:0005524 ALX04_RS04010 e64135893c626f5b8ba2ec04d80445fd 867 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 603 621 1.2E-42 T 28-03-2018 IPR001270 ClpA/B family GO:0005524 ALX04_RS04010 e64135893c626f5b8ba2ec04d80445fd 867 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 677 695 1.2E-42 T 28-03-2018 IPR001270 ClpA/B family GO:0005524 ALX04_RS04010 e64135893c626f5b8ba2ec04d80445fd 867 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 710 724 1.2E-42 T 28-03-2018 IPR001270 ClpA/B family GO:0005524 ALX04_RS04010 e64135893c626f5b8ba2ec04d80445fd 867 SMART SM00382 200 345 1.1E-11 T 28-03-2018 IPR003593 AAA+ ATPase domain ALX04_RS04010 e64135893c626f5b8ba2ec04d80445fd 867 SMART SM00382 599 741 2.1E-13 T 28-03-2018 IPR003593 AAA+ ATPase domain ALX04_RS04010 e64135893c626f5b8ba2ec04d80445fd 867 SUPERFAMILY SSF81923 4 158 2.88E-32 T 28-03-2018 IPR004176 Clp, N-terminal GO:0019538 ALX04_RS04010 e64135893c626f5b8ba2ec04d80445fd 867 Gene3D G3DSA:1.10.8.60 345 549 9.4E-42 T 28-03-2018 ALX04_RS04010 e64135893c626f5b8ba2ec04d80445fd 867 Gene3D G3DSA:3.40.50.300 554 769 3.7E-54 T 28-03-2018 ALX04_RS04010 e64135893c626f5b8ba2ec04d80445fd 867 Gene3D G3DSA:1.10.8.60 770 865 4.8E-25 T 28-03-2018 ALX04_RS04010 e64135893c626f5b8ba2ec04d80445fd 867 ProSitePatterns PS00870 Chaperonins clpA/B signature 1. 296 308 - T 28-03-2018 IPR018368 ClpA/B, conserved site 1 GO:0005524 ALX04_RS04010 e64135893c626f5b8ba2ec04d80445fd 867 Gene3D G3DSA:1.10.1780.10 3 156 7.3E-29 T 28-03-2018 IPR004176 Clp, N-terminal GO:0019538 ALX04_RS15630 c4b945ef4f41c226788f5872182fac0c 309 Gene3D G3DSA:1.10.10.10 60 134 2.8E-6 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS15630 c4b945ef4f41c226788f5872182fac0c 309 Gene3D G3DSA:3.30.420.10 156 309 9.9E-26 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 ALX04_RS15630 c4b945ef4f41c226788f5872182fac0c 309 Pfam PF00665 Integrase core domain 160 259 2.1E-16 T 28-03-2018 IPR001584 Integrase, catalytic core GO:0015074 ALX04_RS15630 c4b945ef4f41c226788f5872182fac0c 309 Pfam PF13936 Helix-turn-helix domain 4 42 8.3E-9 T 28-03-2018 IPR025246 Transposase IS30-like HTH domain ALX04_RS15630 c4b945ef4f41c226788f5872182fac0c 309 Gene3D G3DSA:1.10.10.60 2 48 1.1E-8 T 28-03-2018 ALX04_RS15630 c4b945ef4f41c226788f5872182fac0c 309 SUPERFAMILY SSF53098 158 300 4.43E-28 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 ALX04_RS09260 fc68a0c1f7c2aab3376682b336a3bb45 115 PIRSF PIRSF016134 1 115 2.1E-39 T 28-03-2018 IPR016645 Uncharacterised conserved protein UCP016134 ALX04_RS09260 fc68a0c1f7c2aab3376682b336a3bb45 115 Gene3D G3DSA:2.30.130.30 1 112 1.7E-23 T 28-03-2018 ALX04_RS09260 fc68a0c1f7c2aab3376682b336a3bb45 115 SUPERFAMILY SSF88697 2 112 7.79E-27 T 28-03-2018 IPR015947 PUA-like domain ALX04_RS09260 fc68a0c1f7c2aab3376682b336a3bb45 115 SMART SM01022 4 113 6.5E-10 T 28-03-2018 IPR007374 ASCH domain ALX04_RS06185 dcc28fba98e948fe3c4136098aff4b14 334 Gene3D G3DSA:3.30.420.40 249 313 4.0E-9 T 28-03-2018 ALX04_RS06185 dcc28fba98e948fe3c4136098aff4b14 334 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 181 201 1.7E-56 T 28-03-2018 IPR004753 Cell shape determining protein MreB GO:0000902 ALX04_RS06185 dcc28fba98e948fe3c4136098aff4b14 334 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 126 145 1.7E-56 T 28-03-2018 IPR004753 Cell shape determining protein MreB GO:0000902 ALX04_RS06185 dcc28fba98e948fe3c4136098aff4b14 334 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 44 62 1.7E-56 T 28-03-2018 IPR004753 Cell shape determining protein MreB GO:0000902 ALX04_RS06185 dcc28fba98e948fe3c4136098aff4b14 334 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 296 322 1.7E-56 T 28-03-2018 IPR004753 Cell shape determining protein MreB GO:0000902 ALX04_RS06185 dcc28fba98e948fe3c4136098aff4b14 334 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 64 87 1.7E-56 T 28-03-2018 IPR004753 Cell shape determining protein MreB GO:0000902 ALX04_RS06185 dcc28fba98e948fe3c4136098aff4b14 334 Pfam PF06723 MreB/Mbl protein 7 332 4.7E-137 T 28-03-2018 IPR004753 Cell shape determining protein MreB GO:0000902 ALX04_RS06185 dcc28fba98e948fe3c4136098aff4b14 334 Gene3D G3DSA:3.30.420.40 4 154 6.8E-35 T 28-03-2018 ALX04_RS06185 dcc28fba98e948fe3c4136098aff4b14 334 SUPERFAMILY SSF53067 144 323 3.72E-48 T 28-03-2018 ALX04_RS06185 dcc28fba98e948fe3c4136098aff4b14 334 Gene3D G3DSA:3.90.640.10 188 248 1.7E-24 T 28-03-2018 ALX04_RS06185 dcc28fba98e948fe3c4136098aff4b14 334 Gene3D G3DSA:3.30.420.40 155 187 0.0036 T 28-03-2018 ALX04_RS06185 dcc28fba98e948fe3c4136098aff4b14 334 SUPERFAMILY SSF53067 8 142 3.76E-37 T 28-03-2018 ALX04_RS06185 dcc28fba98e948fe3c4136098aff4b14 334 TIGRFAM TIGR00904 mreB: cell shape determining protein, MreB/Mrl family 7 332 1.0E-142 T 28-03-2018 IPR004753 Cell shape determining protein MreB GO:0000902 ALX04_RS13155 8a031aa95325765bc507ed147adb61f3 190 PRINTS PR01071 Acetyl-CoA biotin carboxyl carrier protein signature 112 125 3.5E-5 T 28-03-2018 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 ALX04_RS13155 8a031aa95325765bc507ed147adb61f3 190 PRINTS PR01071 Acetyl-CoA biotin carboxyl carrier protein signature 144 157 3.5E-5 T 28-03-2018 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 ALX04_RS13155 8a031aa95325765bc507ed147adb61f3 190 PRINTS PR01071 Acetyl-CoA biotin carboxyl carrier protein signature 129 143 3.5E-5 T 28-03-2018 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 ALX04_RS13155 8a031aa95325765bc507ed147adb61f3 190 SUPERFAMILY SSF51230 109 181 1.31E-17 T 28-03-2018 IPR011053 Single hybrid motif ALX04_RS13155 8a031aa95325765bc507ed147adb61f3 190 Gene3D G3DSA:2.40.50.100 126 185 5.4E-13 T 28-03-2018 ALX04_RS13155 8a031aa95325765bc507ed147adb61f3 190 Pfam PF00364 Biotin-requiring enzyme 110 182 2.8E-13 T 28-03-2018 IPR000089 Biotin/lipoyl attachment ALX04_RS06675 cc4ef75768683800669afb6181a49260 380 Pfam PF06152 Phage minor capsid protein 2 9 361 7.5E-81 T 28-03-2018 IPR009319 Bacteriophage A118, Gp4, minor capsid GO:0005198|GO:0019028 ALX04_RS01050 790c6b10c7dd41aa8378b756e244d19c 440 Gene3D G3DSA:3.40.50.2000 6 196 2.9E-6 T 28-03-2018 ALX04_RS01050 790c6b10c7dd41aa8378b756e244d19c 440 Pfam PF00534 Glycosyl transferases group 1 283 397 2.2E-12 T 28-03-2018 IPR001296 Glycosyl transferase, family 1 ALX04_RS01050 790c6b10c7dd41aa8378b756e244d19c 440 SUPERFAMILY SSF53756 1 150 2.0E-29 T 28-03-2018 ALX04_RS01050 790c6b10c7dd41aa8378b756e244d19c 440 SUPERFAMILY SSF53756 218 412 2.0E-29 T 28-03-2018 ALX04_RS01050 790c6b10c7dd41aa8378b756e244d19c 440 Pfam PF08288 PIGA (GPI anchor biosynthesis) 91 137 1.4E-4 T 28-03-2018 IPR013234 PIGA, GPI anchor biosynthesis GO:0006506 Reactome: R-HSA-162710 ALX04_RS01050 790c6b10c7dd41aa8378b756e244d19c 440 Gene3D G3DSA:3.40.50.2000 252 438 7.9E-18 T 28-03-2018 ALX04_RS13730 bffa147d459f37896e5fefd8876b8839 130 Pfam PF02452 PemK-like, MazF-like toxin of type II toxin-antitoxin system 7 113 7.3E-33 T 28-03-2018 IPR003477 mRNA interferase PemK-like GO:0003677 ALX04_RS13730 bffa147d459f37896e5fefd8876b8839 130 Gene3D G3DSA:2.30.30.110 3 119 1.3E-37 T 28-03-2018 IPR011067 Plasmid maintenance toxin/Cell growth inhibitor ALX04_RS13730 bffa147d459f37896e5fefd8876b8839 130 PIRSF PIRSF033490 4 116 2.0E-35 T 28-03-2018 IPR003477 mRNA interferase PemK-like GO:0003677 ALX04_RS13730 bffa147d459f37896e5fefd8876b8839 130 SUPERFAMILY SSF50118 6 116 2.13E-40 T 28-03-2018 IPR011067 Plasmid maintenance toxin/Cell growth inhibitor ALX04_RS00895 cb80094105ba9c148739211e8773196f 457 Gene3D G3DSA:2.40.50.140 1 78 3.3E-20 T 28-03-2018 ALX04_RS00895 cb80094105ba9c148739211e8773196f 457 SUPERFAMILY SSF50249 2 62 5.71E-16 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold ALX04_RS00895 cb80094105ba9c148739211e8773196f 457 TIGRFAM TIGR00479 rumA: 23S rRNA (uracil-5-)-methyltransferase RumA 20 448 3.2E-141 T 28-03-2018 IPR001566 23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD GO:0003723|GO:0006396|GO:0008173 ALX04_RS00895 cb80094105ba9c148739211e8773196f 457 Pfam PF05958 tRNA (Uracil-5-)-methyltransferase 92 455 4.4E-27 T 28-03-2018 IPR010280 (Uracil-5)-methyltransferase family GO:0006396|GO:0008173 ALX04_RS00895 cb80094105ba9c148739211e8773196f 457 Pfam PF01938 TRAM domain 9 62 8.5E-13 T 28-03-2018 IPR002792 TRAM domain ALX04_RS00895 cb80094105ba9c148739211e8773196f 457 SUPERFAMILY SSF53335 72 455 6.15E-81 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase ALX04_RS00895 cb80094105ba9c148739211e8773196f 457 ProSitePatterns PS01231 RNA methyltransferase trmA family signature 2. 438 448 - T 28-03-2018 IPR030391 RNA methyltransferase TrmA, conserved site ALX04_RS00895 cb80094105ba9c148739211e8773196f 457 ProSitePatterns PS01230 RNA methyltransferase trmA family signature 1. 385 416 - T 28-03-2018 IPR030390 RNA methyltransferase TrmA, active site ALX04_RS00895 cb80094105ba9c148739211e8773196f 457 Gene3D G3DSA:3.40.50.150 79 454 4.0E-55 T 28-03-2018 ALX04_RS00695 52a1acfe0ca73e3196067bafcd882596 304 Gene3D G3DSA:3.20.20.360 1 270 1.2E-54 T 28-03-2018 ALX04_RS00695 52a1acfe0ca73e3196067bafcd882596 304 PIRSF PIRSF015582 1 304 1.5E-88 T 28-03-2018 IPR011206 Citrate lyase beta subunit-like ALX04_RS00695 52a1acfe0ca73e3196067bafcd882596 304 Pfam PF03328 HpcH/HpaI aldolase/citrate lyase family 10 229 1.3E-77 T 28-03-2018 IPR005000 HpcH/HpaI aldolase/citrate lyase domain GO:0003824 ALX04_RS00695 52a1acfe0ca73e3196067bafcd882596 304 SUPERFAMILY SSF51621 7 239 3.93E-65 T 28-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 ALX04_RS00695 52a1acfe0ca73e3196067bafcd882596 304 TIGRFAM TIGR01588 citE: citrate (pro-3S)-lyase, beta subunit 7 293 7.5E-143 T 28-03-2018 IPR006475 Citrate lyase, beta subunit, bacteria GO:0005737|GO:0006084|GO:0008816|GO:0009346 KEGG: 00720+4.1.3.34|MetaCyc: PWY-5392|MetaCyc: PWY-6038 ALX04_RS08250 6dddf2a0a60b0abc178eb380f08d8b9d 151 SMART SM00347 27 128 7.5E-8 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 ALX04_RS08250 6dddf2a0a60b0abc178eb380f08d8b9d 151 Pfam PF12802 MarR family 34 92 5.5E-9 T 28-03-2018 ALX04_RS08250 6dddf2a0a60b0abc178eb380f08d8b9d 151 SUPERFAMILY SSF46785 12 143 7.34E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS08250 6dddf2a0a60b0abc178eb380f08d8b9d 151 Gene3D G3DSA:1.10.10.10 3 147 1.4E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS04650 f811f3b685d26b8ded626013da355a66 267 SUPERFAMILY SSF52313 6 235 2.09E-100 T 28-03-2018 IPR023591 Ribosomal protein S2, flavodoxin-like domain ALX04_RS04650 f811f3b685d26b8ded626013da355a66 267 Hamap MF_00291_B 30S ribosomal protein S2 [rpsB]. 2 225 43.548 T 28-03-2018 IPR005706 Ribosomal protein S2, bacteria/mitochondria/plastid GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 ALX04_RS04650 f811f3b685d26b8ded626013da355a66 267 ProSitePatterns PS00963 Ribosomal protein S2 signature 2. 158 182 - T 28-03-2018 IPR018130 Ribosomal protein S2, conserved site GO:0003735|GO:0005840|GO:0006412 ALX04_RS04650 f811f3b685d26b8ded626013da355a66 267 TIGRFAM TIGR01011 rpsB_bact: ribosomal protein uS2 3 226 7.5E-110 T 28-03-2018 IPR005706 Ribosomal protein S2, bacteria/mitochondria/plastid GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 ALX04_RS04650 f811f3b685d26b8ded626013da355a66 267 Gene3D G3DSA:3.40.50.10490 5 260 4.5E-104 T 28-03-2018 ALX04_RS04650 f811f3b685d26b8ded626013da355a66 267 PRINTS PR00395 Ribosomal protein S2 signature 37 46 5.4E-43 T 28-03-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 ALX04_RS04650 f811f3b685d26b8ded626013da355a66 267 PRINTS PR00395 Ribosomal protein S2 signature 6 24 5.4E-43 T 28-03-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 ALX04_RS04650 f811f3b685d26b8ded626013da355a66 267 PRINTS PR00395 Ribosomal protein S2 signature 87 104 5.4E-43 T 28-03-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 ALX04_RS04650 f811f3b685d26b8ded626013da355a66 267 PRINTS PR00395 Ribosomal protein S2 signature 158 175 5.4E-43 T 28-03-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 ALX04_RS04650 f811f3b685d26b8ded626013da355a66 267 PRINTS PR00395 Ribosomal protein S2 signature 196 210 5.4E-43 T 28-03-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 ALX04_RS04650 f811f3b685d26b8ded626013da355a66 267 PRINTS PR00395 Ribosomal protein S2 signature 175 186 5.4E-43 T 28-03-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 ALX04_RS04650 f811f3b685d26b8ded626013da355a66 267 Pfam PF00318 Ribosomal protein S2 9 224 9.7E-100 T 28-03-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 ALX04_RS04650 f811f3b685d26b8ded626013da355a66 267 ProSitePatterns PS00962 Ribosomal protein S2 signature 1. 6 17 - T 28-03-2018 IPR018130 Ribosomal protein S2, conserved site GO:0003735|GO:0005840|GO:0006412 ALX04_RS06625 09cd1bbec2691ecc1e6f189adf47e0a9 1631 SUPERFAMILY SSF53955 1391 1509 4.08E-9 T 28-03-2018 IPR023346 Lysozyme-like domain ALX04_RS06625 09cd1bbec2691ecc1e6f189adf47e0a9 1631 Gene3D G3DSA:1.20.58.60 14 1047 0.14 T 28-03-2018 ALX04_RS06625 09cd1bbec2691ecc1e6f189adf47e0a9 1631 Gene3D G3DSA:1.10.287.700 1164 1262 2.9E-4 T 28-03-2018 ALX04_RS06625 09cd1bbec2691ecc1e6f189adf47e0a9 1631 Gene3D G3DSA:2.70.70.10 1263 1389 1.2E-33 T 28-03-2018 ALX04_RS06625 09cd1bbec2691ecc1e6f189adf47e0a9 1631 TIGRFAM TIGR02675 tape_meas_nterm: tape measure domain 265 330 3.3E-8 T 28-03-2018 IPR013491 Caudovirus, tape measure, N-terminal ALX04_RS06625 09cd1bbec2691ecc1e6f189adf47e0a9 1631 Gene3D G3DSA:1.10.530.10 1390 1555 7.5E-12 T 28-03-2018 ALX04_RS06625 09cd1bbec2691ecc1e6f189adf47e0a9 1631 SUPERFAMILY SSF51261 1264 1379 1.1E-38 T 28-03-2018 IPR011055 Duplicated hybrid motif ALX04_RS06625 09cd1bbec2691ecc1e6f189adf47e0a9 1631 Pfam PF01551 Peptidase family M23 1279 1376 2.5E-27 T 28-03-2018 IPR016047 Peptidase M23 ALX04_RS09690 965bcbdb485eb4b4f33d789626be52e4 98 SUPERFAMILY SSF88659 12 56 1.31E-6 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 ALX04_RS09690 965bcbdb485eb4b4f33d789626be52e4 98 Pfam PF13936 Helix-turn-helix domain 11 54 5.3E-20 T 28-03-2018 IPR025246 Transposase IS30-like HTH domain ALX04_RS09690 965bcbdb485eb4b4f33d789626be52e4 98 Gene3D G3DSA:1.10.10.60 11 56 1.6E-17 T 28-03-2018 ALX04_RS11955 c917fcb456db45d17740ccc07e011b56 547 Gene3D G3DSA:3.90.76.10 63 174 2.7E-27 T 28-03-2018 ALX04_RS11955 c917fcb456db45d17740ccc07e011b56 547 Gene3D G3DSA:3.40.190.10 175 308 9.5E-32 T 28-03-2018 ALX04_RS11955 c917fcb456db45d17740ccc07e011b56 547 Gene3D G3DSA:3.10.105.10 309 516 4.9E-36 T 28-03-2018 ALX04_RS11955 c917fcb456db45d17740ccc07e011b56 547 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 82 467 2.9E-67 T 28-03-2018 IPR000914 Solute-binding protein family 5 domain ALX04_RS11955 c917fcb456db45d17740ccc07e011b56 547 PIRSF PIRSF002741 4 547 5.3E-86 T 28-03-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 ALX04_RS11955 c917fcb456db45d17740ccc07e011b56 547 SUPERFAMILY SSF53850 34 538 6.52E-104 T 28-03-2018 ALX04_RS09160 b9f19b626fbdb4f39257fc6f7960737a 104 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 47 62 8.6E-9 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 ALX04_RS09160 b9f19b626fbdb4f39257fc6f7960737a 104 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 15 30 8.6E-9 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 ALX04_RS09160 b9f19b626fbdb4f39257fc6f7960737a 104 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 62 77 8.6E-9 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 ALX04_RS09160 b9f19b626fbdb4f39257fc6f7960737a 104 SMART SM00418 13 91 4.4E-14 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 ALX04_RS09160 b9f19b626fbdb4f39257fc6f7960737a 104 Gene3D G3DSA:1.10.10.10 2 100 3.9E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS09160 b9f19b626fbdb4f39257fc6f7960737a 104 SUPERFAMILY SSF46785 6 93 2.72E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS09160 b9f19b626fbdb4f39257fc6f7960737a 104 Pfam PF01022 Bacterial regulatory protein, arsR family 22 66 6.6E-9 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 ALX04_RS07945 d4c489bd16b32a9023f3808fb36da448 202 Gene3D G3DSA:3.40.50.360 2 198 5.7E-29 T 28-03-2018 IPR029039 Flavoprotein-like domain ALX04_RS07945 d4c489bd16b32a9023f3808fb36da448 202 SUPERFAMILY SSF52218 3 173 2.37E-39 T 28-03-2018 IPR029039 Flavoprotein-like domain ALX04_RS07945 d4c489bd16b32a9023f3808fb36da448 202 Pfam PF03358 NADPH-dependent FMN reductase 3 147 1.2E-32 T 28-03-2018 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 ALX04_RS12980 d31dd54bba46a63121ff4e71a10c11c5 155 Pfam PF04266 ASCH domain 41 152 1.9E-13 T 28-03-2018 IPR007374 ASCH domain ALX04_RS12980 d31dd54bba46a63121ff4e71a10c11c5 155 PIRSF PIRSF021320 2 155 9.2E-47 T 28-03-2018 IPR009326 Protein of unknown function DUF984 ALX04_RS12980 d31dd54bba46a63121ff4e71a10c11c5 155 SUPERFAMILY SSF88697 4 152 2.49E-48 T 28-03-2018 IPR015947 PUA-like domain ALX04_RS12980 d31dd54bba46a63121ff4e71a10c11c5 155 Gene3D G3DSA:3.10.400.10 4 152 3.5E-41 T 28-03-2018 ALX04_RS12980 d31dd54bba46a63121ff4e71a10c11c5 155 SMART SM01022 27 152 3.8E-30 T 28-03-2018 IPR007374 ASCH domain ALX04_RS14850 d7fdfc4bf4278be188bce3079a6fed0a 178 Pfam PF00929 Exonuclease 4 158 1.6E-24 T 28-03-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III ALX04_RS14850 d7fdfc4bf4278be188bce3079a6fed0a 178 TIGRFAM TIGR00573 dnaq: exonuclease, DNA polymerase III, epsilon subunit family 3 161 2.3E-22 T 28-03-2018 IPR006054 DNA polymerase III epsilon subunit, exonuclease domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 ALX04_RS14850 d7fdfc4bf4278be188bce3079a6fed0a 178 SUPERFAMILY SSF53098 2 162 1.36E-42 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 ALX04_RS14850 d7fdfc4bf4278be188bce3079a6fed0a 178 Gene3D G3DSA:3.30.420.10 1 164 1.1E-36 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 ALX04_RS14850 d7fdfc4bf4278be188bce3079a6fed0a 178 SMART SM00479 2 167 2.0E-24 T 28-03-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III ALX04_RS12990 265708bdf38e1162f965b751e4abb127 175 SUPERFAMILY SSF55729 11 155 1.4E-17 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase ALX04_RS12990 265708bdf38e1162f965b751e4abb127 175 Pfam PF00583 Acetyltransferase (GNAT) family 43 149 4.4E-7 T 28-03-2018 IPR000182 GNAT domain GO:0008080 ALX04_RS12990 265708bdf38e1162f965b751e4abb127 175 Gene3D G3DSA:3.40.630.30 4 155 3.2E-19 T 28-03-2018 ALX04_RS13740 96736ac657662d8e112f72d71f76c7f7 350 Pfam PF09084 NMT1/THI5 like 54 273 6.1E-25 T 28-03-2018 IPR015168 SsuA/THI5-like ALX04_RS13740 96736ac657662d8e112f72d71f76c7f7 350 SUPERFAMILY SSF53850 41 284 1.45E-38 T 28-03-2018 ALX04_RS13740 96736ac657662d8e112f72d71f76c7f7 350 Gene3D G3DSA:3.40.190.10 40 131 5.7E-9 T 28-03-2018 ALX04_RS13740 96736ac657662d8e112f72d71f76c7f7 350 Gene3D G3DSA:3.40.190.10 132 278 3.7E-29 T 28-03-2018 ALX04_RS14690 02a5080c5148f9cb11b0e48277f15753 411 Gene3D G3DSA:3.90.1260.10 160 354 4.6E-85 T 28-03-2018 IPR024074 Argininosuccinate synthetase, catalytic/multimerisation domain body GO:0004055 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 ALX04_RS14690 02a5080c5148f9cb11b0e48277f15753 411 ProSitePatterns PS00565 Argininosuccinate synthase signature 2. 118 129 - T 28-03-2018 IPR018223 Argininosuccinate synthase, conserved site GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 ALX04_RS14690 02a5080c5148f9cb11b0e48277f15753 411 SUPERFAMILY SSF69864 172 399 1.15E-93 T 28-03-2018 ALX04_RS14690 02a5080c5148f9cb11b0e48277f15753 411 Pfam PF00764 Arginosuccinate synthase 9 392 1.7E-172 T 28-03-2018 IPR001518 Argininosuccinate synthase GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 ALX04_RS14690 02a5080c5148f9cb11b0e48277f15753 411 Gene3D G3DSA:3.40.50.620 6 159 3.3E-26 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold ALX04_RS14690 02a5080c5148f9cb11b0e48277f15753 411 TIGRFAM TIGR00032 argG: argininosuccinate synthase 7 396 9.1E-165 T 28-03-2018 IPR001518 Argininosuccinate synthase GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 ALX04_RS14690 02a5080c5148f9cb11b0e48277f15753 411 ProSitePatterns PS00564 Argininosuccinate synthase signature 1. 11 19 - T 28-03-2018 IPR018223 Argininosuccinate synthase, conserved site GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 ALX04_RS14690 02a5080c5148f9cb11b0e48277f15753 411 SUPERFAMILY SSF52402 1 172 1.05E-46 T 28-03-2018 ALX04_RS14690 02a5080c5148f9cb11b0e48277f15753 411 Gene3D G3DSA:1.20.5.470 364 397 2.6E-10 T 28-03-2018 ALX04_RS14690 02a5080c5148f9cb11b0e48277f15753 411 Hamap MF_00005 Argininosuccinate synthase [argG]. 5 398 53.268 T 28-03-2018 IPR023434 Argininosuccinate synthase, type 1 subfamily GO:0004055 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 ALX04_RS08260 8782c4090845830fa6ea0cee11229173 288 Gene3D G3DSA:3.20.20.100 2 276 4.5E-92 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain ALX04_RS08260 8782c4090845830fa6ea0cee11229173 288 SUPERFAMILY SSF51430 2 271 4.06E-89 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain ALX04_RS08260 8782c4090845830fa6ea0cee11229173 288 ProSitePatterns PS00062 Aldo/keto reductase family signature 2. 122 139 - T 28-03-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 ALX04_RS08260 8782c4090845830fa6ea0cee11229173 288 ProSitePatterns PS00063 Aldo/keto reductase family putative active site signature. 228 243 - T 28-03-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 ALX04_RS08260 8782c4090845830fa6ea0cee11229173 288 PRINTS PR00069 Aldo-keto reductase signature 156 185 5.7E-42 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 ALX04_RS08260 8782c4090845830fa6ea0cee11229173 288 PRINTS PR00069 Aldo-keto reductase signature 37 61 5.7E-42 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 ALX04_RS08260 8782c4090845830fa6ea0cee11229173 288 PRINTS PR00069 Aldo-keto reductase signature 122 139 5.7E-42 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 ALX04_RS08260 8782c4090845830fa6ea0cee11229173 288 PRINTS PR00069 Aldo-keto reductase signature 93 111 5.7E-42 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 ALX04_RS08260 8782c4090845830fa6ea0cee11229173 288 PRINTS PR00069 Aldo-keto reductase signature 195 219 5.7E-42 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 ALX04_RS08260 8782c4090845830fa6ea0cee11229173 288 ProSitePatterns PS00798 Aldo/keto reductase family signature 1. 41 58 - T 28-03-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 ALX04_RS08260 8782c4090845830fa6ea0cee11229173 288 PIRSF PIRSF000097 2 117 1.4E-37 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 ALX04_RS08260 8782c4090845830fa6ea0cee11229173 288 PIRSF PIRSF000097 112 274 5.6E-42 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 ALX04_RS08260 8782c4090845830fa6ea0cee11229173 288 Pfam PF00248 Aldo/keto reductase family 25 259 1.4E-48 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain ALX04_RS09350 577ad38e5b2d1e1ccaf666c0ef837dec 593 ProSitePatterns PS00211 ABC transporters family signature. 491 505 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 ALX04_RS09350 577ad38e5b2d1e1ccaf666c0ef837dec 593 Pfam PF00664 ABC transporter transmembrane region 23 298 8.5E-42 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 ALX04_RS09350 577ad38e5b2d1e1ccaf666c0ef837dec 593 Pfam PF00005 ABC transporter 370 519 4.6E-33 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 ALX04_RS09350 577ad38e5b2d1e1ccaf666c0ef837dec 593 SUPERFAMILY SSF90123 9 341 4.84E-64 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 ALX04_RS09350 577ad38e5b2d1e1ccaf666c0ef837dec 593 Gene3D G3DSA:1.20.1560.10 5 342 2.5E-59 T 28-03-2018 ALX04_RS09350 577ad38e5b2d1e1ccaf666c0ef837dec 593 SMART SM00382 379 565 9.9E-13 T 28-03-2018 IPR003593 AAA+ ATPase domain ALX04_RS09350 577ad38e5b2d1e1ccaf666c0ef837dec 593 Gene3D G3DSA:3.40.50.300 343 592 1.6E-71 T 28-03-2018 ALX04_RS09350 577ad38e5b2d1e1ccaf666c0ef837dec 593 SUPERFAMILY SSF52540 347 590 3.17E-87 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase ALX04_RS07710 d0a5eacfabd87890d45bdd269223f6c8 161 SUPERFAMILY SSF52218 4 154 1.05E-16 T 28-03-2018 IPR029039 Flavoprotein-like domain ALX04_RS07710 d0a5eacfabd87890d45bdd269223f6c8 161 Gene3D G3DSA:3.40.50.360 6 153 5.4E-15 T 28-03-2018 IPR029039 Flavoprotein-like domain ALX04_RS07710 d0a5eacfabd87890d45bdd269223f6c8 161 PIRSF PIRSF005087 4 159 3.9E-38 T 28-03-2018 IPR004465 Ribonucleotide reductase Class Ib, NrdI ALX04_RS07710 d0a5eacfabd87890d45bdd269223f6c8 161 Pfam PF07972 NrdI Flavodoxin like 8 145 5.8E-37 T 28-03-2018 IPR004465 Ribonucleotide reductase Class Ib, NrdI ALX04_RS06465 1345a75bb889e7963542403c75dc32d3 339 TIGRFAM TIGR00057 TIGR00057: tRNA threonylcarbamoyl adenosine modification protein, Sua5/YciO/YrdC/YwlC family 9 204 7.9E-62 T 28-03-2018 IPR006070 YrdC-like domain GO:0003725 ALX04_RS06465 1345a75bb889e7963542403c75dc32d3 339 Gene3D G3DSA:3.90.870.10 1 208 3.2E-77 T 28-03-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain ALX04_RS06465 1345a75bb889e7963542403c75dc32d3 339 Pfam PF01300 Telomere recombination 17 193 3.0E-58 T 28-03-2018 IPR006070 YrdC-like domain GO:0003725 ALX04_RS06465 1345a75bb889e7963542403c75dc32d3 339 SUPERFAMILY SSF55821 10 200 1.4E-63 T 28-03-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain ALX04_RS06465 1345a75bb889e7963542403c75dc32d3 339 PIRSF PIRSF004930 1 339 4.9E-127 T 28-03-2018 IPR010923 tRNA threonylcarbamoyladenosine biosynthesis protein SUA5 ALX04_RS06465 1345a75bb889e7963542403c75dc32d3 339 Pfam PF03481 Putative GTP-binding controlling metal-binding 195 333 5.4E-24 T 28-03-2018 IPR005145 Putative GTP-binding controlling metal-binding domain ALX04_RS02305 e7fca7b65fe2dc8c77c493e27f57e8a3 882 SUPERFAMILY SSF47807 175 290 1.79E-33 T 28-03-2018 IPR020045 5'-3' exonuclease, C-terminal domain GO:0003677|GO:0003824 ALX04_RS02305 e7fca7b65fe2dc8c77c493e27f57e8a3 882 SMART SM00474 301 471 2.7E-11 T 28-03-2018 IPR002562 3'-5' exonuclease domain GO:0003676|GO:0006139|GO:0008408 ALX04_RS02305 e7fca7b65fe2dc8c77c493e27f57e8a3 882 Pfam PF00476 DNA polymerase family A 504 880 4.3E-154 T 28-03-2018 IPR001098 DNA-directed DNA polymerase, family A, palm domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 ALX04_RS02305 e7fca7b65fe2dc8c77c493e27f57e8a3 882 Pfam PF02739 5'-3' exonuclease, N-terminal resolvase-like domain 4 174 1.0E-50 T 28-03-2018 IPR020046 5'-3' exonuclease, alpha-helical arch, N-terminal GO:0003677 ALX04_RS02305 e7fca7b65fe2dc8c77c493e27f57e8a3 882 PRINTS PR00868 DNA-polymerase family A (pol I) signature 607 629 6.9E-80 T 28-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 ALX04_RS02305 e7fca7b65fe2dc8c77c493e27f57e8a3 882 PRINTS PR00868 DNA-polymerase family A (pol I) signature 745 756 6.9E-80 T 28-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 ALX04_RS02305 e7fca7b65fe2dc8c77c493e27f57e8a3 882 PRINTS PR00868 DNA-polymerase family A (pol I) signature 630 645 6.9E-80 T 28-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 ALX04_RS02305 e7fca7b65fe2dc8c77c493e27f57e8a3 882 PRINTS PR00868 DNA-polymerase family A (pol I) signature 683 696 6.9E-80 T 28-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 ALX04_RS02305 e7fca7b65fe2dc8c77c493e27f57e8a3 882 PRINTS PR00868 DNA-polymerase family A (pol I) signature 653 676 6.9E-80 T 28-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 ALX04_RS02305 e7fca7b65fe2dc8c77c493e27f57e8a3 882 PRINTS PR00868 DNA-polymerase family A (pol I) signature 829 842 6.9E-80 T 28-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 ALX04_RS02305 e7fca7b65fe2dc8c77c493e27f57e8a3 882 PRINTS PR00868 DNA-polymerase family A (pol I) signature 799 815 6.9E-80 T 28-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 ALX04_RS02305 e7fca7b65fe2dc8c77c493e27f57e8a3 882 PRINTS PR00868 DNA-polymerase family A (pol I) signature 767 778 6.9E-80 T 28-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 ALX04_RS02305 e7fca7b65fe2dc8c77c493e27f57e8a3 882 PRINTS PR00868 DNA-polymerase family A (pol I) signature 708 733 6.9E-80 T 28-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 ALX04_RS02305 e7fca7b65fe2dc8c77c493e27f57e8a3 882 TIGRFAM TIGR00593 pola: DNA polymerase I 5 882 0.0 T 28-03-2018 IPR018320 DNA polymerase 1 GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 ALX04_RS02305 e7fca7b65fe2dc8c77c493e27f57e8a3 882 Gene3D G3DSA:3.30.70.370 607 698 1.6E-14 T 28-03-2018 ALX04_RS02305 e7fca7b65fe2dc8c77c493e27f57e8a3 882 Gene3D G3DSA:3.30.70.370 708 882 6.6E-52 T 28-03-2018 ALX04_RS02305 e7fca7b65fe2dc8c77c493e27f57e8a3 882 Gene3D G3DSA:1.10.150.20 189 267 1.6E-29 T 28-03-2018 ALX04_RS02305 e7fca7b65fe2dc8c77c493e27f57e8a3 882 SUPERFAMILY SSF56672 476 882 3.56E-152 T 28-03-2018 ALX04_RS02305 e7fca7b65fe2dc8c77c493e27f57e8a3 882 SUPERFAMILY SSF53098 310 471 1.97E-36 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 ALX04_RS02305 e7fca7b65fe2dc8c77c493e27f57e8a3 882 Gene3D G3DSA:3.40.50.1010 3 188 8.0E-64 T 28-03-2018 IPR029060 PIN domain-like ALX04_RS02305 e7fca7b65fe2dc8c77c493e27f57e8a3 882 SMART SM00475 3 266 3.6E-134 T 28-03-2018 IPR002421 5'-3' exonuclease, N-terminal GO:0003677 ALX04_RS02305 e7fca7b65fe2dc8c77c493e27f57e8a3 882 SMART SM00279 177 212 1.2E-14 T 28-03-2018 IPR008918 Helix-hairpin-helix motif, class 2 GO:0003677|GO:0003824 ALX04_RS02305 e7fca7b65fe2dc8c77c493e27f57e8a3 882 SUPERFAMILY SSF88723 2 174 1.09E-49 T 28-03-2018 IPR029060 PIN domain-like ALX04_RS02305 e7fca7b65fe2dc8c77c493e27f57e8a3 882 Gene3D G3DSA:1.20.1060.10 425 606 1.3E-55 T 28-03-2018 ALX04_RS02305 e7fca7b65fe2dc8c77c493e27f57e8a3 882 ProSitePatterns PS00447 DNA polymerase family A signature. 708 727 - T 28-03-2018 IPR019760 DNA-directed DNA polymerase, family A, conserved site GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 ALX04_RS02305 e7fca7b65fe2dc8c77c493e27f57e8a3 882 SMART SM00482 638 846 1.7E-110 T 28-03-2018 IPR001098 DNA-directed DNA polymerase, family A, palm domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 ALX04_RS02305 e7fca7b65fe2dc8c77c493e27f57e8a3 882 Pfam PF01367 5'-3' exonuclease, C-terminal SAM fold 175 269 2.3E-32 T 28-03-2018 IPR020045 5'-3' exonuclease, C-terminal domain GO:0003677|GO:0003824 ALX04_RS12860 bc2daa66fc250924ab4b0fe56671a3b6 1300 Gene3D G3DSA:1.10.287.1060 943 1020 1.2E-4 T 28-03-2018 ALX04_RS12860 bc2daa66fc250924ab4b0fe56671a3b6 1300 SUPERFAMILY SSF82866 138 339 2.49E-33 T 28-03-2018 ALX04_RS12860 bc2daa66fc250924ab4b0fe56671a3b6 1300 Gene3D G3DSA:1.20.1640.10 99 336 3.4E-32 T 28-03-2018 ALX04_RS12860 bc2daa66fc250924ab4b0fe56671a3b6 1300 Pfam PF03176 MMPL family 967 1277 9.5E-38 T 28-03-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 ALX04_RS12860 bc2daa66fc250924ab4b0fe56671a3b6 1300 Pfam PF03176 MMPL family 45 364 2.0E-55 T 28-03-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 ALX04_RS12860 bc2daa66fc250924ab4b0fe56671a3b6 1300 Gene3D G3DSA:1.20.5.730 603 667 0.14 T 28-03-2018 ALX04_RS12860 bc2daa66fc250924ab4b0fe56671a3b6 1300 SUPERFAMILY SSF82866 1075 1280 2.09E-30 T 28-03-2018 ALX04_RS12860 bc2daa66fc250924ab4b0fe56671a3b6 1300 Gene3D G3DSA:1.20.1640.10 1060 1292 6.4E-23 T 28-03-2018 ALX04_RS12860 bc2daa66fc250924ab4b0fe56671a3b6 1300 TIGRFAM TIGR03057 xxxLxxG_by_4: X-X-X-Leu-X-X-Gly heptad repeats 958 983 3.6E-5 T 28-03-2018 IPR023908 xxxLxxG heptad repeat ALX04_RS12860 bc2daa66fc250924ab4b0fe56671a3b6 1300 TIGRFAM TIGR03057 xxxLxxG_by_4: X-X-X-Leu-X-X-Gly heptad repeats 564 589 1.3E-6 T 28-03-2018 IPR023908 xxxLxxG heptad repeat ALX04_RS12860 bc2daa66fc250924ab4b0fe56671a3b6 1300 SUPERFAMILY SSF101967 505 655 3.27E-6 T 28-03-2018 ALX04_RS12860 bc2daa66fc250924ab4b0fe56671a3b6 1300 Gene3D G3DSA:1.20.120.570 735 942 4.7E-11 T 28-03-2018 ALX04_RS12860 bc2daa66fc250924ab4b0fe56671a3b6 1300 Gene3D G3DSA:1.20.120.570 399 602 8.9E-17 T 28-03-2018 ALX04_RS00340 f6a6b3100b8cec589e1eb8cd3ee2e131 200 Gene3D G3DSA:1.10.10.60 1 48 4.5E-20 T 28-03-2018 ALX04_RS00340 f6a6b3100b8cec589e1eb8cd3ee2e131 200 SUPERFAMILY SSF46689 3 74 2.26E-19 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 ALX04_RS00340 f6a6b3100b8cec589e1eb8cd3ee2e131 200 ProSitePatterns PS01081 TetR-type HTH domain signature. 27 57 - T 28-03-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site ALX04_RS00340 f6a6b3100b8cec589e1eb8cd3ee2e131 200 Pfam PF00440 Bacterial regulatory proteins, tetR family 15 61 7.1E-19 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 ALX04_RS00340 f6a6b3100b8cec589e1eb8cd3ee2e131 200 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 15 28 5.1E-11 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 ALX04_RS00340 f6a6b3100b8cec589e1eb8cd3ee2e131 200 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 36 59 5.1E-11 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 ALX04_RS00340 f6a6b3100b8cec589e1eb8cd3ee2e131 200 Gene3D G3DSA:1.10.10.60 49 184 2.9E-9 T 28-03-2018 ALX04_RS04265 d2153d27855ca84124af065fe051808f 155 Pfam PF13673 Acetyltransferase (GNAT) domain 54 138 5.7E-15 T 28-03-2018 IPR000182 GNAT domain GO:0008080 ALX04_RS04265 d2153d27855ca84124af065fe051808f 155 SUPERFAMILY SSF55729 12 147 2.48E-21 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase ALX04_RS04265 d2153d27855ca84124af065fe051808f 155 Gene3D G3DSA:3.40.630.30 9 151 7.2E-21 T 28-03-2018 ALX04_RS06055 79082924bd5dc0d68b824fdd1071ff88 203 Pfam PF01330 RuvA N terminal domain 2 60 8.2E-15 T 28-03-2018 IPR013849 DNA helicase, Holliday junction RuvA type, domain I, bacterial GO:0005524|GO:0006281|GO:0006310|GO:0009378 ALX04_RS06055 79082924bd5dc0d68b824fdd1071ff88 203 Gene3D G3DSA:1.10.8.10 138 201 7.6E-8 T 28-03-2018 ALX04_RS06055 79082924bd5dc0d68b824fdd1071ff88 203 Pfam PF14520 Helix-hairpin-helix domain 70 127 5.5E-14 T 28-03-2018 ALX04_RS06055 79082924bd5dc0d68b824fdd1071ff88 203 TIGRFAM TIGR00084 ruvA: Holliday junction DNA helicase RuvA 6 200 1.4E-45 T 28-03-2018 IPR000085 Bacterial DNA recombination protein RuvA GO:0003678|GO:0006281|GO:0006310 ALX04_RS06055 79082924bd5dc0d68b824fdd1071ff88 203 Gene3D G3DSA:1.10.340.30 53 79 4.7E-4 T 28-03-2018 ALX04_RS06055 79082924bd5dc0d68b824fdd1071ff88 203 Gene3D G3DSA:1.10.150.20 80 137 1.7E-16 T 28-03-2018 ALX04_RS06055 79082924bd5dc0d68b824fdd1071ff88 203 SUPERFAMILY SSF47781 64 135 5.4E-21 T 28-03-2018 IPR010994 RuvA domain 2-like ALX04_RS06055 79082924bd5dc0d68b824fdd1071ff88 203 Pfam PF07499 RuvA, C-terminal domain 153 201 6.4E-11 T 28-03-2018 IPR011114 Holliday junction DNA helicase RuvA, C-terminal GO:0005524|GO:0006281|GO:0006310|GO:0009378|GO:0009379 ALX04_RS06055 79082924bd5dc0d68b824fdd1071ff88 203 SUPERFAMILY SSF46929 152 201 7.19E-6 T 28-03-2018 IPR011114 Holliday junction DNA helicase RuvA, C-terminal GO:0005524|GO:0006281|GO:0006310|GO:0009378|GO:0009379 ALX04_RS06055 79082924bd5dc0d68b824fdd1071ff88 203 Hamap MF_00031 Holliday junction ATP-dependent DNA helicase RuvA [ruvA]. 1 201 27.967 T 28-03-2018 IPR000085 Bacterial DNA recombination protein RuvA GO:0003678|GO:0006281|GO:0006310 ALX04_RS06055 79082924bd5dc0d68b824fdd1071ff88 203 SUPERFAMILY SSF50249 2 61 1.37E-11 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold ALX04_RS06055 79082924bd5dc0d68b824fdd1071ff88 203 SMART SM00278 106 125 1.0 T 28-03-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 ALX04_RS06055 79082924bd5dc0d68b824fdd1071ff88 203 SMART SM00278 71 90 0.0081 T 28-03-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 ALX04_RS06055 79082924bd5dc0d68b824fdd1071ff88 203 Gene3D G3DSA:2.40.50.140 2 52 1.5E-15 T 28-03-2018 ALX04_RS01400 7215f4bf5914aea991e66b06d5d27ceb 739 Pfam PF07724 AAA domain (Cdc48 subfamily) 474 639 8.1E-51 T 28-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 ALX04_RS01400 7215f4bf5914aea991e66b06d5d27ceb 739 Gene3D G3DSA:3.40.50.300 107 286 3.2E-25 T 28-03-2018 ALX04_RS01400 7215f4bf5914aea991e66b06d5d27ceb 739 SUPERFAMILY SSF52540 424 711 7.66E-75 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase ALX04_RS01400 7215f4bf5914aea991e66b06d5d27ceb 739 Gene3D G3DSA:1.10.8.60 660 739 8.3E-20 T 28-03-2018 ALX04_RS01400 7215f4bf5914aea991e66b06d5d27ceb 739 SMART SM01086 645 732 3.0E-27 T 28-03-2018 IPR019489 Clp ATPase, C-terminal ALX04_RS01400 7215f4bf5914aea991e66b06d5d27ceb 739 Gene3D G3DSA:1.10.8.60 287 425 2.9E-35 T 28-03-2018 ALX04_RS01400 7215f4bf5914aea991e66b06d5d27ceb 739 SUPERFAMILY SSF46600 353 393 6.67E-6 T 28-03-2018 IPR001943 UVR domain GO:0005515 ALX04_RS01400 7215f4bf5914aea991e66b06d5d27ceb 739 SMART SM00382 144 287 3.8E-11 T 28-03-2018 IPR003593 AAA+ ATPase domain ALX04_RS01400 7215f4bf5914aea991e66b06d5d27ceb 739 SMART SM00382 475 646 7.3E-14 T 28-03-2018 IPR003593 AAA+ ATPase domain ALX04_RS01400 7215f4bf5914aea991e66b06d5d27ceb 739 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 645 715 3.3E-20 T 28-03-2018 IPR019489 Clp ATPase, C-terminal ALX04_RS01400 7215f4bf5914aea991e66b06d5d27ceb 739 Pfam PF02151 UvrB/uvrC motif 359 392 3.2E-7 T 28-03-2018 IPR001943 UVR domain GO:0005515 ALX04_RS01400 7215f4bf5914aea991e66b06d5d27ceb 739 ProSitePatterns PS00870 Chaperonins clpA/B signature 1. 239 251 - T 28-03-2018 IPR018368 ClpA/B, conserved site 1 GO:0005524 ALX04_RS01400 7215f4bf5914aea991e66b06d5d27ceb 739 SUPERFAMILY SSF52540 107 357 6.47E-68 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase ALX04_RS01400 7215f4bf5914aea991e66b06d5d27ceb 739 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 149 278 1.9E-12 T 28-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 ALX04_RS01400 7215f4bf5914aea991e66b06d5d27ceb 739 Gene3D G3DSA:3.40.50.300 426 659 1.9E-46 T 28-03-2018 ALX04_RS01400 7215f4bf5914aea991e66b06d5d27ceb 739 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 586 600 1.7E-37 T 28-03-2018 IPR001270 ClpA/B family GO:0005524 ALX04_RS01400 7215f4bf5914aea991e66b06d5d27ceb 739 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 553 571 1.7E-37 T 28-03-2018 IPR001270 ClpA/B family GO:0005524 ALX04_RS01400 7215f4bf5914aea991e66b06d5d27ceb 739 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 479 497 1.7E-37 T 28-03-2018 IPR001270 ClpA/B family GO:0005524 ALX04_RS01400 7215f4bf5914aea991e66b06d5d27ceb 739 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 524 542 1.7E-37 T 28-03-2018 IPR001270 ClpA/B family GO:0005524 ALX04_RS12710 c7cf3c51e07e935e7e3c8221a89cf777 665 Pfam PF02378 Phosphotransferase system, EIIC 297 582 3.5E-31 T 28-03-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 ALX04_RS12710 c7cf3c51e07e935e7e3c8221a89cf777 665 Gene3D G3DSA:3.30.1360.60 176 252 5.2E-27 T 28-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 ALX04_RS12710 c7cf3c51e07e935e7e3c8221a89cf777 665 SUPERFAMILY SSF51261 4 149 2.79E-45 T 28-03-2018 IPR011055 Duplicated hybrid motif ALX04_RS12710 c7cf3c51e07e935e7e3c8221a89cf777 665 Pfam PF00358 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 8 132 3.1E-45 T 28-03-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 ALX04_RS12710 c7cf3c51e07e935e7e3c8221a89cf777 665 TIGRFAM TIGR00830 PTBA: PTS system, glucose subfamily, IIA component 9 130 9.9E-37 T 28-03-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 ALX04_RS12710 c7cf3c51e07e935e7e3c8221a89cf777 665 SUPERFAMILY SSF55604 178 252 1.24E-21 T 28-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 ALX04_RS12710 c7cf3c51e07e935e7e3c8221a89cf777 665 ProSitePatterns PS01035 PTS EIIB domains cysteine phosphorylation site signature. 191 208 - T 28-03-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 ALX04_RS12710 c7cf3c51e07e935e7e3c8221a89cf777 665 Gene3D G3DSA:2.70.70.10 1 155 5.0E-50 T 28-03-2018 ALX04_RS12710 c7cf3c51e07e935e7e3c8221a89cf777 665 Pfam PF00367 phosphotransferase system, EIIB 181 213 1.9E-13 T 28-03-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 ALX04_RS01965 108ec3b50676e202fc0daa4d864787f6 451 Pfam PF02378 Phosphotransferase system, EIIC 32 348 2.3E-27 T 28-03-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 ALX04_RS01965 108ec3b50676e202fc0daa4d864787f6 451 PIRSF PIRSF006351 2 433 4.9E-115 T 28-03-2018 IPR004796 Phosphotransferase system, cellobiose-type IIC component GO:0008982|GO:0009401|GO:0016021 ALX04_RS08125 1d7d13e2b6f4d31fae46e836341d8bd4 477 PIRSF PIRSF000484 1 474 2.0E-158 T 28-03-2018 IPR007229 Nicotinate phosphoribosyltransferase family KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|Reactome: R-HSA-197264 ALX04_RS08125 1d7d13e2b6f4d31fae46e836341d8bd4 477 Gene3D G3DSA:3.20.140.10 1 383 1.3E-123 T 28-03-2018 ALX04_RS08125 1d7d13e2b6f4d31fae46e836341d8bd4 477 SUPERFAMILY SSF54675 3 133 1.44E-44 T 28-03-2018 ALX04_RS08125 1d7d13e2b6f4d31fae46e836341d8bd4 477 Pfam PF04095 Nicotinate phosphoribosyltransferase (NAPRTase) family 150 336 5.6E-11 T 28-03-2018 IPR007229 Nicotinate phosphoribosyltransferase family KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|Reactome: R-HSA-197264 ALX04_RS08125 1d7d13e2b6f4d31fae46e836341d8bd4 477 SUPERFAMILY SSF51690 134 473 7.36E-107 T 28-03-2018 IPR002638 Quinolinate phosphoribosyl transferase, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 ALX04_RS08125 1d7d13e2b6f4d31fae46e836341d8bd4 477 TIGRFAM TIGR01513 NAPRTase_put: nicotinate phosphoribosyltransferase 5 460 1.0E-159 T 28-03-2018 IPR006405 Nicotinate phosphoribosyltransferase pncB-type GO:0004516|GO:0019358 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|Reactome: R-HSA-197264|Reactome: R-HSA-6798695 ALX04_RS05900 0aa519514d0166b272e78fa7d2f36d7c 306 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 247 260 - T 28-03-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 ALX04_RS05900 0aa519514d0166b272e78fa7d2f36d7c 306 Gene3D G3DSA:3.40.1190.20 1 306 2.4E-70 T 28-03-2018 IPR029056 Ribokinase-like ALX04_RS05900 0aa519514d0166b272e78fa7d2f36d7c 306 Pfam PF00294 pfkB family carbohydrate kinase 1 296 3.7E-61 T 28-03-2018 IPR011611 Carbohydrate kinase PfkB ALX04_RS05900 0aa519514d0166b272e78fa7d2f36d7c 306 Hamap MF_01987 Ribokinase [rbsK]. 2 303 25.961 T 28-03-2018 IPR011877 Ribokinase GO:0004747|GO:0006014 KEGG: 00030+2.7.1.15|Reactome: R-HSA-71336 ALX04_RS05900 0aa519514d0166b272e78fa7d2f36d7c 306 TIGRFAM TIGR02152 D_ribokin_bact: ribokinase 4 301 4.5E-112 T 28-03-2018 IPR011877 Ribokinase GO:0004747|GO:0006014 KEGG: 00030+2.7.1.15|Reactome: R-HSA-71336 ALX04_RS05900 0aa519514d0166b272e78fa7d2f36d7c 306 SUPERFAMILY SSF53613 1 302 1.04E-78 T 28-03-2018 IPR029056 Ribokinase-like ALX04_RS05900 0aa519514d0166b272e78fa7d2f36d7c 306 PRINTS PR00990 Ribokinase signature 105 118 1.7E-32 T 28-03-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 ALX04_RS05900 0aa519514d0166b272e78fa7d2f36d7c 306 PRINTS PR00990 Ribokinase signature 6 27 1.7E-32 T 28-03-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 ALX04_RS05900 0aa519514d0166b272e78fa7d2f36d7c 306 PRINTS PR00990 Ribokinase signature 218 229 1.7E-32 T 28-03-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 ALX04_RS05900 0aa519514d0166b272e78fa7d2f36d7c 306 PRINTS PR00990 Ribokinase signature 33 52 1.7E-32 T 28-03-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 ALX04_RS05900 0aa519514d0166b272e78fa7d2f36d7c 306 PRINTS PR00990 Ribokinase signature 174 189 1.7E-32 T 28-03-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 ALX04_RS10670 63e07aae0e74dcc3478e9594ad8840f0 286 SUPERFAMILY SSF51430 10 272 1.31E-93 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain ALX04_RS10670 63e07aae0e74dcc3478e9594ad8840f0 286 ProSitePatterns PS00063 Aldo/keto reductase family putative active site signature. 240 255 - T 28-03-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 ALX04_RS10670 63e07aae0e74dcc3478e9594ad8840f0 286 PRINTS PR00069 Aldo-keto reductase signature 136 153 2.2E-42 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 ALX04_RS10670 63e07aae0e74dcc3478e9594ad8840f0 286 PRINTS PR00069 Aldo-keto reductase signature 42 66 2.2E-42 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 ALX04_RS10670 63e07aae0e74dcc3478e9594ad8840f0 286 PRINTS PR00069 Aldo-keto reductase signature 98 116 2.2E-42 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 ALX04_RS10670 63e07aae0e74dcc3478e9594ad8840f0 286 PRINTS PR00069 Aldo-keto reductase signature 170 199 2.2E-42 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 ALX04_RS10670 63e07aae0e74dcc3478e9594ad8840f0 286 PRINTS PR00069 Aldo-keto reductase signature 207 231 2.2E-42 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 ALX04_RS10670 63e07aae0e74dcc3478e9594ad8840f0 286 Gene3D G3DSA:3.20.20.100 2 285 8.9E-95 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain ALX04_RS10670 63e07aae0e74dcc3478e9594ad8840f0 286 Pfam PF00248 Aldo/keto reductase family 22 270 1.2E-46 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain ALX04_RS10670 63e07aae0e74dcc3478e9594ad8840f0 286 ProSitePatterns PS00798 Aldo/keto reductase family signature 1. 46 63 - T 28-03-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 ALX04_RS10670 63e07aae0e74dcc3478e9594ad8840f0 286 PIRSF PIRSF000097 4 284 2.5E-83 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 ALX04_RS10670 63e07aae0e74dcc3478e9594ad8840f0 286 ProSitePatterns PS00062 Aldo/keto reductase family signature 2. 136 153 - T 28-03-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 ALX04_RS09715 4e72d3f45b2e5191377d12c10b7cdc30 78 Pfam PF07702 UTRA domain 1 67 2.5E-5 T 28-03-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 ALX04_RS09715 4e72d3f45b2e5191377d12c10b7cdc30 78 Gene3D G3DSA:3.40.1410.10 1 76 2.5E-9 T 28-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain ALX04_RS09715 4e72d3f45b2e5191377d12c10b7cdc30 78 SUPERFAMILY SSF64288 1 74 1.32E-10 T 28-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain ALX04_RS10580 a674f98bbce6eb5c67fbbd9795f874d4 679 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 539 555 7.4E-10 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 ALX04_RS10580 a674f98bbce6eb5c67fbbd9795f874d4 679 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 567 583 7.4E-10 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 ALX04_RS10580 a674f98bbce6eb5c67fbbd9795f874d4 679 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 598 623 7.4E-10 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 ALX04_RS10580 a674f98bbce6eb5c67fbbd9795f874d4 679 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 102 675 3.1E-170 T 28-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 ALX04_RS10580 a674f98bbce6eb5c67fbbd9795f874d4 679 Gene3D G3DSA:3.40.1110.10 384 535 4.4E-34 T 28-03-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 ALX04_RS10580 a674f98bbce6eb5c67fbbd9795f874d4 679 SUPERFAMILY SSF56784 427 673 3.38E-55 T 28-03-2018 IPR023214 HAD-like domain ALX04_RS10580 a674f98bbce6eb5c67fbbd9795f874d4 679 SUPERFAMILY SSF56784 369 387 3.38E-55 T 28-03-2018 IPR023214 HAD-like domain ALX04_RS10580 a674f98bbce6eb5c67fbbd9795f874d4 679 SUPERFAMILY SSF81653 173 270 1.44E-23 T 28-03-2018 IPR008250 P-type ATPase, A domain Reactome: R-HSA-936837 ALX04_RS10580 a674f98bbce6eb5c67fbbd9795f874d4 679 TIGRFAM TIGR01511 ATPase-IB1_Cu: copper-translocating P-type ATPase 84 676 1.7E-183 T 28-03-2018 ALX04_RS10580 a674f98bbce6eb5c67fbbd9795f874d4 679 Pfam PF00122 E1-E2 ATPase 170 347 8.1E-47 T 28-03-2018 ALX04_RS10580 a674f98bbce6eb5c67fbbd9795f874d4 679 SUPERFAMILY SSF81665 271 361 9.94E-12 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 ALX04_RS10580 a674f98bbce6eb5c67fbbd9795f874d4 679 SUPERFAMILY SSF81665 129 174 9.94E-12 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 ALX04_RS10580 a674f98bbce6eb5c67fbbd9795f874d4 679 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 220 234 4.6E-22 T 28-03-2018 ALX04_RS10580 a674f98bbce6eb5c67fbbd9795f874d4 679 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 567 586 4.6E-22 T 28-03-2018 ALX04_RS10580 a674f98bbce6eb5c67fbbd9795f874d4 679 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 369 383 4.6E-22 T 28-03-2018 ALX04_RS10580 a674f98bbce6eb5c67fbbd9795f874d4 679 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 514 524 4.6E-22 T 28-03-2018 ALX04_RS10580 a674f98bbce6eb5c67fbbd9795f874d4 679 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 590 602 4.6E-22 T 28-03-2018 ALX04_RS10580 a674f98bbce6eb5c67fbbd9795f874d4 679 Pfam PF00702 haloacid dehalogenase-like hydrolase 367 581 3.5E-40 T 28-03-2018 ALX04_RS10580 a674f98bbce6eb5c67fbbd9795f874d4 679 Gene3D G3DSA:1.20.1110.10 100 383 4.3E-32 T 28-03-2018 ALX04_RS10580 a674f98bbce6eb5c67fbbd9795f874d4 679 Gene3D G3DSA:3.40.50.1000 539 611 3.7E-21 T 28-03-2018 IPR023214 HAD-like domain ALX04_RS10580 a674f98bbce6eb5c67fbbd9795f874d4 679 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 371 377 - T 28-03-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 ALX04_RS10580 a674f98bbce6eb5c67fbbd9795f874d4 679 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 143 645 5.2E-84 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 ALX04_RS00510 8317d394aa283c8470106a0ae4c35a90 314 Gene3D G3DSA:1.10.150.20 241 314 7.0E-27 T 28-03-2018 ALX04_RS00510 8317d394aa283c8470106a0ae4c35a90 314 Pfam PF03118 Bacterial RNA polymerase, alpha chain C terminal domain 240 304 8.3E-29 T 28-03-2018 IPR011260 RNA polymerase, alpha subunit, C-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 ALX04_RS00510 8317d394aa283c8470106a0ae4c35a90 314 SUPERFAMILY SSF55257 4 48 5.49E-34 T 28-03-2018 IPR009025 DNA-directed RNA polymerase, RBP11-like dimerisation domain GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 ALX04_RS00510 8317d394aa283c8470106a0ae4c35a90 314 SUPERFAMILY SSF55257 172 226 5.49E-34 T 28-03-2018 IPR009025 DNA-directed RNA polymerase, RBP11-like dimerisation domain GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 ALX04_RS00510 8317d394aa283c8470106a0ae4c35a90 314 Pfam PF01000 RNA polymerase Rpb3/RpoA insert domain 57 150 4.5E-25 T 28-03-2018 IPR011262 DNA-directed RNA polymerase, insert domain GO:0003899|GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 ALX04_RS00510 8317d394aa283c8470106a0ae4c35a90 314 SUPERFAMILY SSF56553 48 171 8.24E-44 T 28-03-2018 IPR011262 DNA-directed RNA polymerase, insert domain GO:0003899|GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 ALX04_RS00510 8317d394aa283c8470106a0ae4c35a90 314 SUPERFAMILY SSF47789 247 312 3.01E-24 T 28-03-2018 ALX04_RS00510 8317d394aa283c8470106a0ae4c35a90 314 ProDom PD001179 RNA POLYMERASE ALPHA DNA-DIRECTED SUBUNIT CHAIN NUCLEOTIDYLTRANSFERASE TRANSFERASE TRANSCRIPTION TRANSCRIPTASE 253 310 1.0E-25 T 28-03-2018 IPR011260 RNA polymerase, alpha subunit, C-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 ALX04_RS00510 8317d394aa283c8470106a0ae4c35a90 314 Hamap MF_00059 DNA-directed RNA polymerase subunit alpha [rpoA]. 1 313 37.282 T 28-03-2018 IPR011773 DNA-directed RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 ALX04_RS00510 8317d394aa283c8470106a0ae4c35a90 314 TIGRFAM TIGR02027 rpoA: DNA-directed RNA polymerase, alpha subunit 18 312 1.1E-124 T 28-03-2018 IPR011773 DNA-directed RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 ALX04_RS00510 8317d394aa283c8470106a0ae4c35a90 314 SMART SM00662 18 227 3.0E-101 T 28-03-2018 IPR011263 DNA-directed RNA polymerase, RpoA/D/Rpb3-type GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 ALX04_RS00510 8317d394aa283c8470106a0ae4c35a90 314 Pfam PF01193 RNA polymerase Rpb3/Rpb11 dimerisation domain 24 221 6.8E-24 T 28-03-2018 IPR011263 DNA-directed RNA polymerase, RpoA/D/Rpb3-type GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 ALX04_RS00510 8317d394aa283c8470106a0ae4c35a90 314 Gene3D G3DSA:3.30.1360.10 1 110 7.5E-21 T 28-03-2018 ALX04_RS00510 8317d394aa283c8470106a0ae4c35a90 314 Gene3D G3DSA:3.30.1360.10 111 224 2.2E-27 T 28-03-2018 ALX04_RS16070 3e180f3e66da393635352acb0276916c 210 Gene3D G3DSA:1.20.5.40 114 142 3.2E-8 T 28-03-2018 ALX04_RS16070 3e180f3e66da393635352acb0276916c 210 ProSitePatterns PS00397 Site-specific recombinases active site. 5 13 - T 28-03-2018 IPR006118 Recombinase, conserved site GO:0000150|GO:0006310 ALX04_RS16070 3e180f3e66da393635352acb0276916c 210 Gene3D G3DSA:3.40.50.1390 1 113 1.3E-28 T 28-03-2018 ALX04_RS16070 3e180f3e66da393635352acb0276916c 210 Gene3D G3DSA:1.10.10.60 145 198 2.4E-7 T 28-03-2018 ALX04_RS16070 3e180f3e66da393635352acb0276916c 210 Pfam PF02796 Helix-turn-helix domain of resolvase 146 193 1.2E-9 T 28-03-2018 IPR006120 Resolvase, HTH domain GO:0000150|GO:0003677|GO:0006310 ALX04_RS16070 3e180f3e66da393635352acb0276916c 210 SUPERFAMILY SSF53041 1 144 9.68E-35 T 28-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 ALX04_RS16070 3e180f3e66da393635352acb0276916c 210 SMART SM00857 2 144 1.6E-38 T 28-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 ALX04_RS16070 3e180f3e66da393635352acb0276916c 210 Pfam PF00239 Resolvase, N terminal domain 3 144 3.2E-34 T 28-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 ALX04_RS08160 1a17ed606bb2174e694816ccc4d8073f 115 Pfam PF02255 PTS system, Lactose/Cellobiose specific IIA subunit 15 107 4.8E-37 T 28-03-2018 IPR003188 Phosphotransferase system, lactose/cellobiose-type IIA subunit GO:0009401 ALX04_RS08160 1a17ed606bb2174e694816ccc4d8073f 115 SUPERFAMILY SSF46973 13 108 1.57E-36 T 28-03-2018 IPR003188 Phosphotransferase system, lactose/cellobiose-type IIA subunit GO:0009401 ALX04_RS08160 1a17ed606bb2174e694816ccc4d8073f 115 PIRSF PIRSF000699 4 114 7.4E-36 T 28-03-2018 IPR003188 Phosphotransferase system, lactose/cellobiose-type IIA subunit GO:0009401 ALX04_RS08160 1a17ed606bb2174e694816ccc4d8073f 115 Gene3D G3DSA:1.20.58.80 10 108 9.0E-38 T 28-03-2018 IPR003188 Phosphotransferase system, lactose/cellobiose-type IIA subunit GO:0009401 ALX04_RS05665 c7b39e4c0a06c4242a6dd4e055783744 132 TIGRFAM TIGR01617 arsC_related: transcriptional regulator, Spx/MgsR family 4 114 1.1E-37 T 28-03-2018 IPR006504 Transcriptional regulator Spx/MgsR ALX04_RS05665 c7b39e4c0a06c4242a6dd4e055783744 132 Pfam PF03960 ArsC family 6 113 5.2E-23 T 28-03-2018 IPR006660 Arsenate reductase-like ALX04_RS05665 c7b39e4c0a06c4242a6dd4e055783744 132 SUPERFAMILY SSF52833 1 129 9.61E-40 T 28-03-2018 IPR012336 Thioredoxin-like fold ALX04_RS05665 c7b39e4c0a06c4242a6dd4e055783744 132 Gene3D G3DSA:3.40.30.10 1 131 2.9E-36 T 28-03-2018 ALX04_RS05665 c7b39e4c0a06c4242a6dd4e055783744 132 Hamap MF_01132 Regulatory protein Spx [spxA]. 1 131 38.74 T 28-03-2018 IPR023731 Regulatory protein Spx GO:0045892 ALX04_RS15230 f3384434ca878e498063337deff75e6d 145 Gene3D G3DSA:3.90.79.10 1 139 6.7E-26 T 28-03-2018 ALX04_RS15230 f3384434ca878e498063337deff75e6d 145 ProSitePatterns PS00893 Nudix box signature. 48 69 - T 28-03-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 ALX04_RS15230 f3384434ca878e498063337deff75e6d 145 SUPERFAMILY SSF55811 15 142 3.25E-28 T 28-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 ALX04_RS15230 f3384434ca878e498063337deff75e6d 145 PRINTS PR00502 NUDIX hydrolase family signature 57 72 5.6E-8 T 28-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 ALX04_RS15230 f3384434ca878e498063337deff75e6d 145 PRINTS PR00502 NUDIX hydrolase family signature 43 57 5.6E-8 T 28-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 ALX04_RS15230 f3384434ca878e498063337deff75e6d 145 Pfam PF00293 NUDIX domain 21 135 9.7E-18 T 28-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 ALX04_RS11385 5fb6c0bedafe7afc6910a242071642ab 198 Hamap MF_00784 Accessory gene regulator protein B [agrB]. 9 193 16.666 T 28-03-2018 IPR006741 Accessory gene regulator B GO:0008233|GO:0009372|GO:0009405|GO:0016021 ALX04_RS11385 5fb6c0bedafe7afc6910a242071642ab 198 SMART SM00793 12 192 1.3E-58 T 28-03-2018 IPR006741 Accessory gene regulator B GO:0008233|GO:0009372|GO:0009405|GO:0016021 ALX04_RS11385 5fb6c0bedafe7afc6910a242071642ab 198 Pfam PF04647 Accessory gene regulator B 15 184 2.0E-32 T 28-03-2018 IPR006741 Accessory gene regulator B GO:0008233|GO:0009372|GO:0009405|GO:0016021 ALX04_RS03860 7116dc787bde77ab8276f32f759c8b1b 283 SUPERFAMILY SSF82549 3 279 6.02E-78 T 28-03-2018 ALX04_RS03860 7116dc787bde77ab8276f32f759c8b1b 283 Gene3D G3DSA:2.20.28.50 32 54 5.8E-18 T 28-03-2018 ALX04_RS03860 7116dc787bde77ab8276f32f759c8b1b 283 Gene3D G3DSA:3.30.1180.10 152 281 1.5E-28 T 28-03-2018 ALX04_RS03860 7116dc787bde77ab8276f32f759c8b1b 283 Gene3D G3DSA:3.40.50.10440 55 149 2.2E-26 T 28-03-2018 ALX04_RS03860 7116dc787bde77ab8276f32f759c8b1b 283 Gene3D G3DSA:3.40.50.10440 2 31 0.0039 T 28-03-2018 ALX04_RS03860 7116dc787bde77ab8276f32f759c8b1b 283 Pfam PF02645 Uncharacterised protein, DegV family COG1307 3 277 2.7E-75 T 28-03-2018 IPR003797 DegV ALX04_RS03860 7116dc787bde77ab8276f32f759c8b1b 283 TIGRFAM TIGR00762 DegV: EDD domain protein, DegV family 4 277 3.7E-87 T 28-03-2018 IPR003797 DegV ALX04_RS09770 3302b6a3cea938877a0dd1cedf18dbd0 261 Gene3D G3DSA:3.40.50.150 77 235 2.3E-31 T 28-03-2018 ALX04_RS09770 3302b6a3cea938877a0dd1cedf18dbd0 261 SUPERFAMILY SSF53335 80 239 2.61E-34 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase ALX04_RS09770 3302b6a3cea938877a0dd1cedf18dbd0 261 ProSitePatterns PS01184 ubiE/COQ5 methyltransferase family signature 2. 197 211 - T 28-03-2018 IPR023576 UbiE/COQ5 methyltransferase, conserved site GO:0008168 KEGG: 00130+2.1.1.163|KEGG: 00564+2.1.1.16|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895 ALX04_RS09770 3302b6a3cea938877a0dd1cedf18dbd0 261 Pfam PF13649 Methyltransferase domain 97 203 1.2E-20 T 28-03-2018 ALX04_RS15040 bcce26900a998457e6dc58961224f416 302 TIGRFAM TIGR01250 pro_imino_pep_2: proline-specific peptidase 3 292 6.4E-126 T 28-03-2018 IPR005945 Proline-specific peptidase GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 ALX04_RS15040 bcce26900a998457e6dc58961224f416 302 Pfam PF00561 alpha/beta hydrolase fold 28 279 9.2E-23 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 ALX04_RS15040 bcce26900a998457e6dc58961224f416 302 Gene3D G3DSA:3.40.50.1820 2 293 3.0E-42 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold ALX04_RS15040 bcce26900a998457e6dc58961224f416 302 SUPERFAMILY SSF53474 9 291 4.35E-56 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold ALX04_RS15040 bcce26900a998457e6dc58961224f416 302 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 56 67 2.6E-11 T 28-03-2018 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 ALX04_RS15040 bcce26900a998457e6dc58961224f416 302 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 105 119 2.6E-11 T 28-03-2018 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 ALX04_RS15040 bcce26900a998457e6dc58961224f416 302 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 28 36 2.6E-11 T 28-03-2018 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 ALX04_RS15040 bcce26900a998457e6dc58961224f416 302 PIRSF PIRSF005539 1 300 2.4E-100 T 28-03-2018 IPR005945 Proline-specific peptidase GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 ALX04_RS00435 3a6b540c3c558eb11810921c3e30f033 103 Pfam PF00467 KOW motif 6 36 2.7E-8 T 28-03-2018 IPR005824 KOW ALX04_RS00435 3a6b540c3c558eb11810921c3e30f033 103 SUPERFAMILY SSF50104 2 98 2.71E-35 T 28-03-2018 IPR008991 Translation protein SH3-like domain ALX04_RS00435 3a6b540c3c558eb11810921c3e30f033 103 Gene3D G3DSA:2.30.30.30 1 91 1.4E-34 T 28-03-2018 IPR014722 Ribosomal protein L2 domain 2 ALX04_RS00435 3a6b540c3c558eb11810921c3e30f033 103 Pfam PF17136 Ribosomal proteins 50S L24/mitochondrial 39S L24 38 100 6.6E-29 T 28-03-2018 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 ALX04_RS00435 3a6b540c3c558eb11810921c3e30f033 103 Hamap MF_01326_B 50S ribosomal protein L24 [rplX]. 1 95 19.936 T 28-03-2018 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 ALX04_RS00435 3a6b540c3c558eb11810921c3e30f033 103 SMART SM00739 2 29 2.9E-5 T 28-03-2018 IPR005824 KOW ALX04_RS00435 3a6b540c3c558eb11810921c3e30f033 103 ProSitePatterns PS01108 Ribosomal protein L24 signature. 6 23 - T 28-03-2018 IPR005825 Ribosomal protein L24/L26, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 ALX04_RS00435 3a6b540c3c558eb11810921c3e30f033 103 TIGRFAM TIGR01079 rplX_bact: ribosomal protein uL24 3 100 1.1E-35 T 28-03-2018 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 ALX04_RS05880 e6e5a12bc2ac8ca4fd9c1eaab875704d 157 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 5 28 1.2E-6 T 28-03-2018 IPR012902 Prokaryotic N-terminal methylation site ALX04_RS05880 e6e5a12bc2ac8ca4fd9c1eaab875704d 157 Gene3D G3DSA:3.30.700.10 8 152 5.6E-5 T 28-03-2018 ALX04_RS05880 e6e5a12bc2ac8ca4fd9c1eaab875704d 157 Pfam PF07963 Prokaryotic N-terminal methylation motif 4 27 4.2E-5 T 28-03-2018 IPR012902 Prokaryotic N-terminal methylation site ALX04_RS05880 e6e5a12bc2ac8ca4fd9c1eaab875704d 157 SUPERFAMILY SSF54523 8 110 8.63E-8 T 28-03-2018 ALX04_RS05880 e6e5a12bc2ac8ca4fd9c1eaab875704d 157 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 6 26 - T 28-03-2018 IPR012902 Prokaryotic N-terminal methylation site ALX04_RS14550 f2b6ee985101215126cfe2141895c231 242 SMART SM00862 160 236 6.6E-30 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 ALX04_RS14550 f2b6ee985101215126cfe2141895c231 242 Pfam PF00486 Transcriptional regulatory protein, C terminal 160 236 3.2E-29 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 ALX04_RS14550 f2b6ee985101215126cfe2141895c231 242 SUPERFAMILY SSF46894 137 237 7.09E-33 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 ALX04_RS14550 f2b6ee985101215126cfe2141895c231 242 Gene3D G3DSA:1.10.10.10 147 241 4.5E-33 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS14550 f2b6ee985101215126cfe2141895c231 242 Gene3D G3DSA:3.40.50.2300 3 146 5.5E-37 T 28-03-2018 ALX04_RS14550 f2b6ee985101215126cfe2141895c231 242 SMART SM00448 4 115 9.2E-44 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 ALX04_RS14550 f2b6ee985101215126cfe2141895c231 242 Pfam PF00072 Response regulator receiver domain 6 115 6.0E-31 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 ALX04_RS14550 f2b6ee985101215126cfe2141895c231 242 SUPERFAMILY SSF52172 2 126 9.25E-42 T 28-03-2018 IPR011006 CheY-like superfamily ALX04_RS06905 e9df2e85b6e630be962542f4d9a722b1 368 TIGRFAM TIGR01537 portal_HK97: phage portal protein, HK97 family 36 351 5.7E-69 T 28-03-2018 IPR006427 Phage portal protein, HK97 ALX04_RS06905 e9df2e85b6e630be962542f4d9a722b1 368 Pfam PF04860 Phage portal protein 42 343 6.0E-61 T 28-03-2018 IPR006944 Bacteriophage/Gene transfer agent portal protein ALX04_RS05470 6abc1d5673d66b27d0617fd272d154ef 152 Pfam PF04397 LytTr DNA-binding domain 55 150 5.3E-15 T 28-03-2018 IPR007492 LytTR DNA-binding domain GO:0003677 ALX04_RS05470 6abc1d5673d66b27d0617fd272d154ef 152 Gene3D G3DSA:2.40.50.40 45 114 2.6E-8 T 28-03-2018 ALX04_RS05470 6abc1d5673d66b27d0617fd272d154ef 152 SMART SM00850 54 151 2.0E-14 T 28-03-2018 IPR007492 LytTR DNA-binding domain GO:0003677 ALX04_RS05470 6abc1d5673d66b27d0617fd272d154ef 152 Gene3D G3DSA:2.20.25.10 118 151 3.6E-4 T 28-03-2018 ALX04_RS05130 7ebe278a53678f65649703af9780a497 342 Pfam PF00534 Glycosyl transferases group 1 170 310 8.0E-16 T 28-03-2018 IPR001296 Glycosyl transferase, family 1 ALX04_RS05130 7ebe278a53678f65649703af9780a497 342 Gene3D G3DSA:3.40.50.2000 1 162 2.1E-11 T 28-03-2018 ALX04_RS05130 7ebe278a53678f65649703af9780a497 342 Gene3D G3DSA:3.40.50.2000 163 318 1.2E-23 T 28-03-2018 ALX04_RS05130 7ebe278a53678f65649703af9780a497 342 SUPERFAMILY SSF53756 1 340 2.04E-50 T 28-03-2018 ALX04_RS05130 7ebe278a53678f65649703af9780a497 342 Pfam PF13439 Glycosyltransferase Family 4 14 158 2.4E-13 T 28-03-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193 ALX04_RS02790 d37c51e8cab006071b21148d1b8db92a 408 Gene3D G3DSA:3.40.50.1950 2 184 4.5E-48 T 28-03-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 ALX04_RS02790 d37c51e8cab006071b21148d1b8db92a 408 Pfam PF04127 DNA / pantothenate metabolism flavoprotein 190 374 1.0E-72 T 28-03-2018 IPR007085 DNA/pantothenate metabolism flavoprotein, C-terminal KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 ALX04_RS02790 d37c51e8cab006071b21148d1b8db92a 408 Gene3D G3DSA:3.40.50.10300 185 404 1.1E-68 T 28-03-2018 IPR007085 DNA/pantothenate metabolism flavoprotein, C-terminal KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 ALX04_RS02790 d37c51e8cab006071b21148d1b8db92a 408 TIGRFAM TIGR00521 coaBC_dfp: phosphopantothenoylcysteine decarboxylase / phosphopantothenate--cysteine ligase 6 397 5.6E-129 T 28-03-2018 IPR005252 Coenzyme A biosynthesis bifunctional protein CoaBC GO:0004632|GO:0004633|GO:0010181|GO:0015937|GO:0015941 KEGG: 00770+4.1.1.36+6.3.2.5|MetaCyc: PWY-7851 ALX04_RS02790 d37c51e8cab006071b21148d1b8db92a 408 SUPERFAMILY SSF52507 2 179 6.54E-52 T 28-03-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 ALX04_RS02790 d37c51e8cab006071b21148d1b8db92a 408 Pfam PF02441 Flavoprotein 8 180 3.9E-40 T 28-03-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 ALX04_RS02790 d37c51e8cab006071b21148d1b8db92a 408 SUPERFAMILY SSF102645 189 397 4.45E-72 T 28-03-2018 IPR007085 DNA/pantothenate metabolism flavoprotein, C-terminal KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 ALX04_RS07705 bab61b599cc53fda07a43696b8bb9da0 455 Gene3D G3DSA:3.10.580.10 204 354 1.4E-31 T 28-03-2018 ALX04_RS07705 bab61b599cc53fda07a43696b8bb9da0 455 Pfam PF03471 Transporter associated domain 362 439 1.9E-12 T 28-03-2018 IPR005170 Transporter-associated domain ALX04_RS07705 bab61b599cc53fda07a43696b8bb9da0 455 SMART SM01091 361 441 1.9E-16 T 28-03-2018 IPR005170 Transporter-associated domain ALX04_RS07705 bab61b599cc53fda07a43696b8bb9da0 455 Pfam PF01595 Domain of unknown function DUF21 12 208 1.0E-38 T 28-03-2018 IPR002550 Domain of unknown function DUF21 ALX04_RS07705 bab61b599cc53fda07a43696b8bb9da0 455 Pfam PF00571 CBS domain 226 281 3.2E-8 T 28-03-2018 IPR000644 CBS domain ALX04_RS07705 bab61b599cc53fda07a43696b8bb9da0 455 Pfam PF00571 CBS domain 296 344 5.0E-8 T 28-03-2018 IPR000644 CBS domain ALX04_RS07705 bab61b599cc53fda07a43696b8bb9da0 455 Gene3D G3DSA:3.30.465.10 355 441 1.6E-16 T 28-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 ALX04_RS07705 bab61b599cc53fda07a43696b8bb9da0 455 SUPERFAMILY SSF56176 358 438 3.27E-15 T 28-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 ALX04_RS07705 bab61b599cc53fda07a43696b8bb9da0 455 SMART SM00116 297 345 2.5 T 28-03-2018 IPR000644 CBS domain ALX04_RS07705 bab61b599cc53fda07a43696b8bb9da0 455 SMART SM00116 234 284 8.1E-6 T 28-03-2018 IPR000644 CBS domain ALX04_RS07705 bab61b599cc53fda07a43696b8bb9da0 455 SUPERFAMILY SSF54631 215 355 4.42E-31 T 28-03-2018 ALX04_RS04815 269ee154e4651dae4f92cf0c4a5c6da9 217 Pfam PF04630 Phage tail tube protein 1 201 4.4E-59 T 28-03-2018 IPR006724 Phage tail tube protein 1 ALX04_RS13420 911ad87939105866b6fcd4bb5638bc79 228 Pfam PF02517 CAAX protease self-immunity 125 220 1.7E-13 T 28-03-2018 IPR003675 CAAX amino terminal protease GO:0016020 Reactome: R-HSA-5689880 ALX04_RS15865 a3ce1882e9560eeb8e84fb3e54f6f417 397 SUPERFAMILY SSF52540 43 270 6.18E-71 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase ALX04_RS15865 a3ce1882e9560eeb8e84fb3e54f6f417 397 Gene3D G3DSA:3.10.580.10 274 397 2.5E-17 T 28-03-2018 ALX04_RS15865 a3ce1882e9560eeb8e84fb3e54f6f417 397 TIGRFAM TIGR01186 proV: glycine betaine/L-proline transport ATP binding subunit 37 392 4.3E-130 T 28-03-2018 IPR005892 Glycine betaine transport ATP-binding subunit GO:0005524|GO:0016020|GO:0031460 ALX04_RS15865 a3ce1882e9560eeb8e84fb3e54f6f417 397 ProSitePatterns PS00211 ABC transporters family signature. 165 179 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 ALX04_RS15865 a3ce1882e9560eeb8e84fb3e54f6f417 397 Gene3D G3DSA:3.40.50.300 2 273 9.3E-66 T 28-03-2018 ALX04_RS15865 a3ce1882e9560eeb8e84fb3e54f6f417 397 Pfam PF00571 CBS domain 295 327 0.002 T 28-03-2018 IPR000644 CBS domain ALX04_RS15865 a3ce1882e9560eeb8e84fb3e54f6f417 397 Pfam PF00571 CBS domain 338 391 5.1E-5 T 28-03-2018 IPR000644 CBS domain ALX04_RS15865 a3ce1882e9560eeb8e84fb3e54f6f417 397 SMART SM00382 53 250 3.4E-16 T 28-03-2018 IPR003593 AAA+ ATPase domain ALX04_RS15865 a3ce1882e9560eeb8e84fb3e54f6f417 397 SUPERFAMILY SSF54631 274 393 6.44E-17 T 28-03-2018 ALX04_RS15865 a3ce1882e9560eeb8e84fb3e54f6f417 397 Pfam PF00005 ABC transporter 45 192 2.8E-31 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 ALX04_RS11665 94b41f92d36ec71b75b4984a7311737b 479 SUPERFAMILY SSF53756 6 479 1.63E-119 T 28-03-2018 ALX04_RS11665 94b41f92d36ec71b75b4984a7311737b 479 Pfam PF08323 Starch synthase catalytic domain 3 238 2.7E-79 T 28-03-2018 IPR013534 Starch synthase, catalytic domain KEGG: 00500+2.4.1.21|MetaCyc: PWY-622 ALX04_RS11665 94b41f92d36ec71b75b4984a7311737b 479 Hamap MF_00484 Glycogen synthase [glgA]. 2 477 43.321 T 28-03-2018 IPR011835 Bacterial/plant glycogen synthase GO:0004373 KEGG: 00500+2.4.1.21|MetaCyc: PWY-622 ALX04_RS11665 94b41f92d36ec71b75b4984a7311737b 479 Gene3D G3DSA:3.40.50.2000 3 264 1.0E-6 T 28-03-2018 ALX04_RS11665 94b41f92d36ec71b75b4984a7311737b 479 Gene3D G3DSA:3.40.50.2000 265 473 5.3E-39 T 28-03-2018 ALX04_RS11665 94b41f92d36ec71b75b4984a7311737b 479 TIGRFAM TIGR02095 glgA: glycogen/starch synthase, ADP-glucose type 3 477 1.5E-172 T 28-03-2018 IPR011835 Bacterial/plant glycogen synthase GO:0004373 KEGG: 00500+2.4.1.21|MetaCyc: PWY-622 ALX04_RS11665 94b41f92d36ec71b75b4984a7311737b 479 Pfam PF00534 Glycosyl transferases group 1 292 431 2.5E-17 T 28-03-2018 IPR001296 Glycosyl transferase, family 1 ALX04_RS04165 552e3d36970521d41df58fb3fd8f8aff 295 SUPERFAMILY SSF53098 122 285 1.82E-27 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 ALX04_RS04165 552e3d36970521d41df58fb3fd8f8aff 295 Gene3D G3DSA:3.30.420.10 122 294 5.1E-29 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 ALX04_RS04165 552e3d36970521d41df58fb3fd8f8aff 295 Pfam PF00665 Integrase core domain 127 246 2.8E-17 T 28-03-2018 IPR001584 Integrase, catalytic core GO:0015074 ALX04_RS04165 552e3d36970521d41df58fb3fd8f8aff 295 Pfam PF13276 HTH-like domain 42 96 7.6E-14 T 28-03-2018 IPR025948 HTH-like domain ALX04_RS00485 9d9ec9383973688de0f0d3bf9536729c 219 PRINTS PR00094 Adenylate kinase signature 164 179 6.1E-28 T 28-03-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 ALX04_RS00485 9d9ec9383973688de0f0d3bf9536729c 219 PRINTS PR00094 Adenylate kinase signature 84 100 6.1E-28 T 28-03-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 ALX04_RS00485 9d9ec9383973688de0f0d3bf9536729c 219 PRINTS PR00094 Adenylate kinase signature 35 49 6.1E-28 T 28-03-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 ALX04_RS00485 9d9ec9383973688de0f0d3bf9536729c 219 PRINTS PR00094 Adenylate kinase signature 181 195 6.1E-28 T 28-03-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 ALX04_RS00485 9d9ec9383973688de0f0d3bf9536729c 219 PRINTS PR00094 Adenylate kinase signature 7 20 6.1E-28 T 28-03-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 ALX04_RS00485 9d9ec9383973688de0f0d3bf9536729c 219 Pfam PF05191 Adenylate kinase, active site lid 130 166 3.4E-14 T 28-03-2018 IPR007862 Adenylate kinase, active site lid domain GO:0004017 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219 ALX04_RS00485 9d9ec9383973688de0f0d3bf9536729c 219 Pfam PF00406 Adenylate kinase 8 193 4.9E-54 T 28-03-2018 ALX04_RS00485 9d9ec9383973688de0f0d3bf9536729c 219 TIGRFAM TIGR01351 adk: adenylate kinase 5 216 7.0E-77 T 28-03-2018 IPR006259 Adenylate kinase subfamily GO:0004017|GO:0005524|GO:0016776 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219 ALX04_RS00485 9d9ec9383973688de0f0d3bf9536729c 219 ProSitePatterns PS00113 Adenylate kinase signature. 84 95 - T 28-03-2018 IPR033690 Adenylate kinase, conserved site KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 ALX04_RS00485 9d9ec9383973688de0f0d3bf9536729c 219 Gene3D G3DSA:3.40.50.300 4 219 1.5E-56 T 28-03-2018 ALX04_RS00485 9d9ec9383973688de0f0d3bf9536729c 219 SUPERFAMILY SSF52540 4 218 1.74E-43 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase ALX04_RS00485 9d9ec9383973688de0f0d3bf9536729c 219 Hamap MF_00235 Adenylate kinase [adk]. 4 217 50.501 T 28-03-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 ALX04_RS02915 ae6c24073b1a84a556240303a505b763 106 Gene3D G3DSA:1.20.1440.50 10 86 1.6E-4 T 28-03-2018 IPR023130 Ta0600-like domain ALX04_RS06245 4a7cda4cf2434a0572a3cf467e718a4a 208 Pfam PF06335 Protein of unknown function (DUF1054) 2 195 2.8E-64 T 28-03-2018 IPR009403 Protein of unknown function UPF0637 ALX04_RS06245 4a7cda4cf2434a0572a3cf467e718a4a 208 PIRSF PIRSF021332 1 201 3.2E-78 T 28-03-2018 IPR009403 Protein of unknown function UPF0637 ALX04_RS06245 4a7cda4cf2434a0572a3cf467e718a4a 208 SUPERFAMILY SSF142913 2 201 7.06E-66 T 28-03-2018 ALX04_RS06245 4a7cda4cf2434a0572a3cf467e718a4a 208 Hamap MF_01851 UPF0637 protein . 1 197 35.048 T 28-03-2018 IPR009403 Protein of unknown function UPF0637 ALX04_RS05895 6418a0c7bda3e80d3fa86eddc5e1951a 324 Gene3D G3DSA:3.30.450.90 2 109 1.1E-21 T 28-03-2018 ALX04_RS05895 6418a0c7bda3e80d3fa86eddc5e1951a 324 Pfam PF00437 Type II/IV secretion system protein 10 269 2.1E-48 T 28-03-2018 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 ALX04_RS05895 6418a0c7bda3e80d3fa86eddc5e1951a 324 Gene3D G3DSA:3.40.50.300 111 308 4.6E-24 T 28-03-2018 ALX04_RS05895 6418a0c7bda3e80d3fa86eddc5e1951a 324 SUPERFAMILY SSF52540 3 278 9.01E-54 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase ALX04_RS03955 afef7fd8c023010c7f0ffcf702c7b738 238 ProSitePatterns PS01149 Rsu family of pseudouridine synthase signature. 100 114 - T 28-03-2018 IPR018496 Pseudouridine synthase, RsuA/RluB/E/F, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0016866 ALX04_RS03955 afef7fd8c023010c7f0ffcf702c7b738 238 SUPERFAMILY SSF55120 47 230 2.4E-45 T 28-03-2018 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 ALX04_RS03955 afef7fd8c023010c7f0ffcf702c7b738 238 Gene3D G3DSA:3.10.290.10 1 61 2.8E-18 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 ALX04_RS03955 afef7fd8c023010c7f0ffcf702c7b738 238 Gene3D G3DSA:3.30.2350.10 62 238 2.4E-43 T 28-03-2018 ALX04_RS03955 afef7fd8c023010c7f0ffcf702c7b738 238 SMART SM00363 3 60 1.5E-13 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 ALX04_RS03955 afef7fd8c023010c7f0ffcf702c7b738 238 Pfam PF01479 S4 domain 3 49 8.0E-14 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 ALX04_RS03955 afef7fd8c023010c7f0ffcf702c7b738 238 SUPERFAMILY SSF55174 3 68 3.14E-16 T 28-03-2018 ALX04_RS03955 afef7fd8c023010c7f0ffcf702c7b738 238 Pfam PF00849 RNA pseudouridylate synthase 63 197 6.1E-26 T 28-03-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 ALX04_RS03955 afef7fd8c023010c7f0ffcf702c7b738 238 TIGRFAM TIGR00093 TIGR00093: pseudouridine synthase 67 227 4.2E-52 T 28-03-2018 IPR000748 Pseudouridine synthase, RsuA/RluB/E/F GO:0001522|GO:0003723|GO:0009451|GO:0016866 ALX04_RS07295 cdc702326b2a3c5663a85f35dcc54ee1 208 Hamap MF_00278 Imidazole glycerol phosphate synthase subunit HisH [hisH]. 1 199 32.837 T 28-03-2018 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 ALX04_RS07295 cdc702326b2a3c5663a85f35dcc54ee1 208 TIGRFAM TIGR01855 IMP_synth_hisH: imidazole glycerol phosphate synthase, glutamine amidotransferase subunit 3 199 1.3E-59 T 28-03-2018 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 ALX04_RS07295 cdc702326b2a3c5663a85f35dcc54ee1 208 SUPERFAMILY SSF52317 3 196 1.53E-49 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like ALX04_RS07295 cdc702326b2a3c5663a85f35dcc54ee1 208 Pfam PF00117 Glutamine amidotransferase class-I 4 189 4.0E-20 T 28-03-2018 IPR017926 Glutamine amidotransferase ALX04_RS07295 cdc702326b2a3c5663a85f35dcc54ee1 208 PIRSF PIRSF000495 1 202 7.3E-70 T 28-03-2018 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 ALX04_RS07295 cdc702326b2a3c5663a85f35dcc54ee1 208 Gene3D G3DSA:3.40.50.880 1 207 3.2E-43 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like ALX04_RS05955 4e119d2e7de4f21b5b0232d478b1c7c0 236 Hamap MF_01691 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase [dapH]. 1 235 45.771 T 28-03-2018 IPR019873 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase, DapH GO:0009089|GO:0047200 KEGG: 00300+2.3.1.89|MetaCyc: PWY-2941 ALX04_RS05955 4e119d2e7de4f21b5b0232d478b1c7c0 236 Pfam PF14602 Hexapeptide repeat of succinyl-transferase 165 198 2.2E-7 T 28-03-2018 IPR001451 Hexapeptide repeat ALX04_RS05955 4e119d2e7de4f21b5b0232d478b1c7c0 236 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 174 202 - T 28-03-2018 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 ALX04_RS05955 4e119d2e7de4f21b5b0232d478b1c7c0 236 Gene3D G3DSA:3.30.70.250 3 82 1.7E-36 T 28-03-2018 ALX04_RS05955 4e119d2e7de4f21b5b0232d478b1c7c0 236 SUPERFAMILY SSF51161 88 226 1.22E-48 T 28-03-2018 IPR011004 Trimeric LpxA-like ALX04_RS05955 4e119d2e7de4f21b5b0232d478b1c7c0 236 TIGRFAM TIGR03532 DapD_Ac: 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase 6 236 3.6E-123 T 28-03-2018 IPR019873 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase, DapH GO:0009089|GO:0047200 KEGG: 00300+2.3.1.89|MetaCyc: PWY-2941 ALX04_RS05955 4e119d2e7de4f21b5b0232d478b1c7c0 236 Gene3D G3DSA:2.160.10.10 83 234 3.4E-42 T 28-03-2018 ALX04_RS05955 4e119d2e7de4f21b5b0232d478b1c7c0 236 Pfam PF08503 Tetrahydrodipicolinate succinyltransferase N-terminal 4 87 1.1E-34 T 28-03-2018 IPR013710 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase, N-terminal GO:0047200 KEGG: 00300+2.3.1.89|MetaCyc: PWY-2941 ALX04_RS05955 4e119d2e7de4f21b5b0232d478b1c7c0 236 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 91 119 1.8E-4 T 28-03-2018 IPR001451 Hexapeptide repeat ALX04_RS05955 4e119d2e7de4f21b5b0232d478b1c7c0 236 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 122 156 4.9E-9 T 28-03-2018 IPR001451 Hexapeptide repeat ALX04_RS11845 a7ad5183d0e9c4e7728e48b7fc4487aa 447 Pfam PF06738 Putative threonine/serine exporter 43 286 3.6E-65 T 28-03-2018 IPR010619 Putative threonine/serine exporter ALX04_RS11845 a7ad5183d0e9c4e7728e48b7fc4487aa 447 Pfam PF12821 Threonine/Serine exporter, ThrE 312 435 9.1E-18 T 28-03-2018 IPR024528 Threonine/Serine exporter, ThrE ALX04_RS03515 82ea405d9635b61fa53f4257f8624476 307 Gene3D G3DSA:3.10.290.10 12 74 1.1E-12 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 ALX04_RS03515 82ea405d9635b61fa53f4257f8624476 307 SUPERFAMILY SSF55174 18 103 3.14E-14 T 28-03-2018 ALX04_RS03515 82ea405d9635b61fa53f4257f8624476 307 Pfam PF00849 RNA pseudouridylate synthase 90 242 3.6E-35 T 28-03-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 ALX04_RS03515 82ea405d9635b61fa53f4257f8624476 307 Pfam PF01479 S4 domain 18 63 8.5E-10 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 ALX04_RS03515 82ea405d9635b61fa53f4257f8624476 307 SMART SM00363 17 81 1.5E-7 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 ALX04_RS03515 82ea405d9635b61fa53f4257f8624476 307 ProSitePatterns PS01129 Rlu family of pseudouridine synthase signature. 135 149 - T 28-03-2018 IPR006224 Pseudouridine synthase, RluC/RluD, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0009982 ALX04_RS03515 82ea405d9635b61fa53f4257f8624476 307 Gene3D G3DSA:3.30.2350.10 81 304 2.8E-76 T 28-03-2018 ALX04_RS03515 82ea405d9635b61fa53f4257f8624476 307 TIGRFAM TIGR00005 rluA_subfam: pseudouridine synthase, RluA family 16 300 4.5E-99 T 28-03-2018 IPR006225 Pseudouridine synthase, RluC/RluD GO:0001522|GO:0003723|GO:0009451|GO:0009982 ALX04_RS03515 82ea405d9635b61fa53f4257f8624476 307 SUPERFAMILY SSF55120 75 301 1.3E-78 T 28-03-2018 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 ALX04_RS11740 f1151789eb75bdb98990c18b692c9b3f 420 Pfam PF13365 Trypsin-like peptidase domain 123 269 6.4E-29 T 28-03-2018 ALX04_RS11740 f1151789eb75bdb98990c18b692c9b3f 420 SUPERFAMILY SSF50156 297 407 6.31E-17 T 28-03-2018 IPR001478 PDZ domain GO:0005515 ALX04_RS11740 f1151789eb75bdb98990c18b692c9b3f 420 SMART SM00228 284 399 1.6E-4 T 28-03-2018 IPR001478 PDZ domain GO:0005515 ALX04_RS11740 f1151789eb75bdb98990c18b692c9b3f 420 SUPERFAMILY SSF50494 64 307 4.76E-54 T 28-03-2018 IPR009003 Peptidase S1, PA clan ALX04_RS11740 f1151789eb75bdb98990c18b692c9b3f 420 PRINTS PR00834 HtrA/DegQ protease family signature 156 176 9.6E-37 T 28-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 ALX04_RS11740 f1151789eb75bdb98990c18b692c9b3f 420 PRINTS PR00834 HtrA/DegQ protease family signature 357 369 9.6E-37 T 28-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 ALX04_RS11740 f1151789eb75bdb98990c18b692c9b3f 420 PRINTS PR00834 HtrA/DegQ protease family signature 135 147 9.6E-37 T 28-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 ALX04_RS11740 f1151789eb75bdb98990c18b692c9b3f 420 PRINTS PR00834 HtrA/DegQ protease family signature 240 257 9.6E-37 T 28-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 ALX04_RS11740 f1151789eb75bdb98990c18b692c9b3f 420 PRINTS PR00834 HtrA/DegQ protease family signature 197 221 9.6E-37 T 28-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 ALX04_RS11740 f1151789eb75bdb98990c18b692c9b3f 420 PRINTS PR00834 HtrA/DegQ protease family signature 262 279 9.6E-37 T 28-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 ALX04_RS11740 f1151789eb75bdb98990c18b692c9b3f 420 Gene3D G3DSA:2.40.10.10 61 197 3.8E-29 T 28-03-2018 ALX04_RS11740 f1151789eb75bdb98990c18b692c9b3f 420 Gene3D G3DSA:2.30.42.10 314 418 5.2E-22 T 28-03-2018 ALX04_RS11740 f1151789eb75bdb98990c18b692c9b3f 420 Pfam PF13180 PDZ domain 311 408 3.7E-21 T 28-03-2018 IPR001478 PDZ domain GO:0005515 ALX04_RS11740 f1151789eb75bdb98990c18b692c9b3f 420 Gene3D G3DSA:2.40.10.10 198 313 3.6E-33 T 28-03-2018 ALX04_RS12150 f0fbebc3ffef06568262c2f13784b3d1 121 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 41 56 6.4E-11 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 ALX04_RS12150 f0fbebc3ffef06568262c2f13784b3d1 121 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 75 90 6.4E-11 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 ALX04_RS12150 f0fbebc3ffef06568262c2f13784b3d1 121 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 90 105 6.4E-11 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 ALX04_RS12150 f0fbebc3ffef06568262c2f13784b3d1 121 Pfam PF12840 Helix-turn-helix domain 40 97 6.1E-14 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS12150 f0fbebc3ffef06568262c2f13784b3d1 121 Gene3D G3DSA:1.10.10.10 19 121 4.8E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS12150 f0fbebc3ffef06568262c2f13784b3d1 121 SUPERFAMILY SSF46785 27 117 2.73E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS12150 f0fbebc3ffef06568262c2f13784b3d1 121 SMART SM00418 39 119 9.2E-19 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 ALX04_RS06810 8d2bbfe004e1c817ebb555cf33b83932 448 Pfam PF10544 T5orf172 domain 327 418 8.2E-15 T 28-03-2018 IPR018306 Bacteriophage T5, Orf172 DNA-binding ALX04_RS06810 8d2bbfe004e1c817ebb555cf33b83932 448 Pfam PF13250 Domain of unknown function (DUF4041) 169 224 4.1E-19 T 28-03-2018 IPR025280 Domain of unknown function DUF4041 ALX04_RS06810 8d2bbfe004e1c817ebb555cf33b83932 448 SMART SM00974 337 420 3.8E-28 T 28-03-2018 IPR018306 Bacteriophage T5, Orf172 DNA-binding ALX04_RS08485 70b597c2285378a80e5549c98338e256 247 Gene3D G3DSA:3.40.50.10090 1 45 6.2E-12 T 28-03-2018 ALX04_RS08485 70b597c2285378a80e5549c98338e256 247 Pfam PF00106 short chain dehydrogenase 6 200 5.4E-57 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR ALX04_RS08485 70b597c2285378a80e5549c98338e256 247 Gene3D G3DSA:3.40.50.720 46 241 9.4E-45 T 28-03-2018 ALX04_RS08485 70b597c2285378a80e5549c98338e256 247 SUPERFAMILY SSF51735 2 233 1.6E-64 T 28-03-2018 IPR016040 NAD(P)-binding domain ALX04_RS08485 70b597c2285378a80e5549c98338e256 247 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 6 190 9.2E-4 T 28-03-2018 ALX04_RS08485 70b597c2285378a80e5549c98338e256 247 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 141 169 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 ALX04_RS08485 70b597c2285378a80e5549c98338e256 247 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 134 142 2.3E-7 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR ALX04_RS08485 70b597c2285378a80e5549c98338e256 247 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 81 92 2.3E-7 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR ALX04_RS08485 70b597c2285378a80e5549c98338e256 247 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 154 173 2.3E-7 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR ALX04_RS08485 70b597c2285378a80e5549c98338e256 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 81 92 1.4E-23 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR ALX04_RS08485 70b597c2285378a80e5549c98338e256 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 154 173 1.4E-23 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR ALX04_RS08485 70b597c2285378a80e5549c98338e256 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 1.4E-23 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR ALX04_RS08485 70b597c2285378a80e5549c98338e256 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 128 144 1.4E-23 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR ALX04_RS08485 70b597c2285378a80e5549c98338e256 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 177 194 1.4E-23 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR ALX04_RS03275 29fefbec1e53ee173fc52ab7870ded70 455 SUPERFAMILY SSF53335 3 293 2.59E-59 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase ALX04_RS03275 29fefbec1e53ee173fc52ab7870ded70 455 Pfam PF17125 N-terminal domain of 16S rRNA methyltransferase RsmF 3 85 1.8E-21 T 28-03-2018 IPR031341 Ribosomal RNA small subunit methyltransferase F, N-terminal KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825|Reactome: R-HSA-6790901|Reactome: R-HSA-8869496 ALX04_RS03275 29fefbec1e53ee173fc52ab7870ded70 455 Pfam PF17126 RsmF rRNA methyltransferase first C-terminal domain 321 381 2.2E-17 T 28-03-2018 IPR031340 Ribosomal RNA small subunit methyltransferase F, first C-terminal domain KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 ALX04_RS03275 29fefbec1e53ee173fc52ab7870ded70 455 ProSitePatterns PS01153 NOL1/NOP2/sun family signature. 166 177 - T 28-03-2018 IPR018314 Bacterial Fmu (Sun)/eukaryotic nucleolar NOL1/Nop2p, conserved site GO:0003723|GO:0008168 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 ALX04_RS03275 29fefbec1e53ee173fc52ab7870ded70 455 Pfam PF13636 RNA-binding PUA-like domain of methyltransferase RsmF 399 445 4.9E-14 T 28-03-2018 IPR027391 rRNA small subunit methyltransferase F, RNA-binding PUA-like domain KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 ALX04_RS03275 29fefbec1e53ee173fc52ab7870ded70 455 Pfam PF01189 16S rRNA methyltransferase RsmB/F 92 292 1.7E-47 T 28-03-2018 IPR001678 SAM-dependent methyltransferase RsmB/NOP2-type GO:0008168 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 ALX04_RS03275 29fefbec1e53ee173fc52ab7870ded70 455 Gene3D G3DSA:3.40.50.150 80 302 1.7E-58 T 28-03-2018 ALX04_RS03275 29fefbec1e53ee173fc52ab7870ded70 455 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 100 110 1.8E-24 T 28-03-2018 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 ALX04_RS03275 29fefbec1e53ee173fc52ab7870ded70 455 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 71 85 1.8E-24 T 28-03-2018 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 ALX04_RS03275 29fefbec1e53ee173fc52ab7870ded70 455 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 167 179 1.8E-24 T 28-03-2018 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 ALX04_RS03275 29fefbec1e53ee173fc52ab7870ded70 455 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 277 294 1.8E-24 T 28-03-2018 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 ALX04_RS03275 29fefbec1e53ee173fc52ab7870ded70 455 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 217 233 1.8E-24 T 28-03-2018 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 ALX04_RS00550 22e87a94d9edfa0e2f9b989971598866 281 SMART SM00382 34 219 6.4E-18 T 28-03-2018 IPR003593 AAA+ ATPase domain ALX04_RS00550 22e87a94d9edfa0e2f9b989971598866 281 Pfam PF00005 ABC transporter 25 171 2.6E-36 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 ALX04_RS00550 22e87a94d9edfa0e2f9b989971598866 281 Gene3D G3DSA:3.40.50.300 1 268 1.5E-71 T 28-03-2018 ALX04_RS00550 22e87a94d9edfa0e2f9b989971598866 281 ProSitePatterns PS00211 ABC transporters family signature. 143 157 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 ALX04_RS00550 22e87a94d9edfa0e2f9b989971598866 281 SUPERFAMILY SSF52540 4 233 6.56E-65 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase ALX04_RS00550 22e87a94d9edfa0e2f9b989971598866 281 TIGRFAM TIGR04520 ECF_ATPase_1: energy-coupling factor transporter ATPase 6 275 6.7E-116 T 28-03-2018 IPR030947 Energy-coupling factor transporter ATP-binding protein EcfA1 ALX04_RS00265 ff79e95d18a62add43191f689b4afcb6 174 SUPERFAMILY SSF46785 6 138 1.58E-24 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS00265 ff79e95d18a62add43191f689b4afcb6 174 ProSitePatterns PS01332 Rrf2-type HTH domain signature. 49 67 - T 28-03-2018 IPR030489 Transcription regulator Rrf2-type, conserved site ALX04_RS00265 ff79e95d18a62add43191f689b4afcb6 174 Gene3D G3DSA:1.10.10.10 1 146 4.9E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS00265 ff79e95d18a62add43191f689b4afcb6 174 TIGRFAM TIGR00738 rrf2_super: Rrf2 family protein 1 139 3.1E-22 T 28-03-2018 IPR000944 Transcription regulator Rrf2-type ALX04_RS00265 ff79e95d18a62add43191f689b4afcb6 174 Pfam PF02082 Transcriptional regulator 1 83 1.6E-21 T 28-03-2018 IPR000944 Transcription regulator Rrf2-type ALX04_RS14685 1456c9aa462bcc656915aad37fa3f164 158 Pfam PF02664 S-Ribosylhomocysteinase (LuxS) 3 148 2.0E-52 T 28-03-2018 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 ALX04_RS14685 1456c9aa462bcc656915aad37fa3f164 158 ProDom PD013172 LYASE SYNTHESIS LUXS AUTOINDUCER-2 PRODUCTION AUTOINDUCER S-RIBOSYLHOMOCYSTEINE AI-2 QUORUM SENSING 9 150 2.0E-80 T 28-03-2018 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 ALX04_RS14685 1456c9aa462bcc656915aad37fa3f164 158 Hamap MF_00091 S-ribosylhomocysteine lyase [luxS]. 1 155 35.381 T 28-03-2018 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 ALX04_RS14685 1456c9aa462bcc656915aad37fa3f164 158 SUPERFAMILY SSF63411 3 156 3.11E-60 T 28-03-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 ALX04_RS14685 1456c9aa462bcc656915aad37fa3f164 158 Gene3D G3DSA:3.30.1360.80 1 145 1.5E-55 T 28-03-2018 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 ALX04_RS14685 1456c9aa462bcc656915aad37fa3f164 158 PRINTS PR01487 Bacterial autoinducer-2 (AI-2) production protein LuxS signature 49 67 8.7E-33 T 28-03-2018 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 ALX04_RS14685 1456c9aa462bcc656915aad37fa3f164 158 PRINTS PR01487 Bacterial autoinducer-2 (AI-2) production protein LuxS signature 5 23 8.7E-33 T 28-03-2018 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 ALX04_RS14685 1456c9aa462bcc656915aad37fa3f164 158 PRINTS PR01487 Bacterial autoinducer-2 (AI-2) production protein LuxS signature 28 46 8.7E-33 T 28-03-2018 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 ALX04_RS14685 1456c9aa462bcc656915aad37fa3f164 158 PRINTS PR01487 Bacterial autoinducer-2 (AI-2) production protein LuxS signature 73 91 8.7E-33 T 28-03-2018 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 ALX04_RS14685 1456c9aa462bcc656915aad37fa3f164 158 PRINTS PR01487 Bacterial autoinducer-2 (AI-2) production protein LuxS signature 117 136 8.7E-33 T 28-03-2018 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 ALX04_RS14685 1456c9aa462bcc656915aad37fa3f164 158 PIRSF PIRSF006160 1 158 5.0E-62 T 28-03-2018 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 ALX04_RS14395 7ce9e3f1f0885315694a86a3dff78970 339 Gene3D G3DSA:3.40.50.300 19 171 9.1E-26 T 28-03-2018 ALX04_RS14395 7ce9e3f1f0885315694a86a3dff78970 339 TIGRFAM TIGR00678 holB: DNA polymerase III, delta' subunit 21 203 2.1E-62 T 28-03-2018 IPR004622 DNA polymerase III, delta prime subunit GO:0003887|GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 ALX04_RS14395 7ce9e3f1f0885315694a86a3dff78970 339 Pfam PF13177 DNA polymerase III, delta subunit 15 173 1.9E-55 T 28-03-2018 ALX04_RS14395 7ce9e3f1f0885315694a86a3dff78970 339 Gene3D G3DSA:1.20.272.10 211 339 3.8E-14 T 28-03-2018 ALX04_RS14395 7ce9e3f1f0885315694a86a3dff78970 339 SUPERFAMILY SSF52540 15 202 1.63E-44 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase ALX04_RS04415 234d8a71521626be6f1c6ceb5050374a 598 Pfam PF00152 tRNA synthetases class II (D, K and N) 122 561 2.1E-107 T 28-03-2018 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 ALX04_RS04415 234d8a71521626be6f1c6ceb5050374a 598 Hamap MF_00044 Aspartate--tRNA(Asp/Asn) ligase [aspS]. 2 588 33.716 T 28-03-2018 IPR004524 Aspartate-tRNA ligase, type 1 GO:0005524|GO:0016874 Reactome: R-HSA-379726 ALX04_RS04415 234d8a71521626be6f1c6ceb5050374a 598 Gene3D G3DSA:2.40.50.140 1 110 7.9E-25 T 28-03-2018 ALX04_RS04415 234d8a71521626be6f1c6ceb5050374a 598 TIGRFAM TIGR00459 aspS_bact: aspartate--tRNA ligase 1 586 7.5E-235 T 28-03-2018 IPR004524 Aspartate-tRNA ligase, type 1 GO:0005524|GO:0016874 Reactome: R-HSA-379726 ALX04_RS04415 234d8a71521626be6f1c6ceb5050374a 598 PRINTS PR01042 Aspartyl-tRNA synthetase signature 194 206 1.0E-24 T 28-03-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 ALX04_RS04415 234d8a71521626be6f1c6ceb5050374a 598 PRINTS PR01042 Aspartyl-tRNA synthetase signature 211 224 1.0E-24 T 28-03-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 ALX04_RS04415 234d8a71521626be6f1c6ceb5050374a 598 PRINTS PR01042 Aspartyl-tRNA synthetase signature 522 536 1.0E-24 T 28-03-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 ALX04_RS04415 234d8a71521626be6f1c6ceb5050374a 598 PRINTS PR01042 Aspartyl-tRNA synthetase signature 478 494 1.0E-24 T 28-03-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 ALX04_RS04415 234d8a71521626be6f1c6ceb5050374a 598 Pfam PF01336 OB-fold nucleic acid binding domain 19 103 3.2E-14 T 28-03-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 ALX04_RS04415 234d8a71521626be6f1c6ceb5050374a 598 Pfam PF02938 GAD domain 312 407 2.8E-29 T 28-03-2018 IPR029351 GAD domain Reactome: R-HSA-379726 ALX04_RS04415 234d8a71521626be6f1c6ceb5050374a 598 SUPERFAMILY SSF55681 426 588 6.77E-103 T 28-03-2018 ALX04_RS04415 234d8a71521626be6f1c6ceb5050374a 598 SUPERFAMILY SSF55681 112 296 6.77E-103 T 28-03-2018 ALX04_RS04415 234d8a71521626be6f1c6ceb5050374a 598 Gene3D G3DSA:3.30.930.10 135 590 1.3E-101 T 28-03-2018 ALX04_RS04415 234d8a71521626be6f1c6ceb5050374a 598 SUPERFAMILY SSF50249 3 107 7.62E-29 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold ALX04_RS04415 234d8a71521626be6f1c6ceb5050374a 598 SUPERFAMILY SSF55261 293 421 2.94E-40 T 28-03-2018 IPR004115 GAD-like domain GO:0004812|GO:0005524|GO:0005737 Reactome: R-HSA-379726 ALX04_RS07825 d93c2a73ca7be1e8e99d05cb8156e5bf 364 PRINTS PR00096 Glutamine amidotransferase superfamily signature 239 250 3.7E-11 T 28-03-2018 ALX04_RS07825 d93c2a73ca7be1e8e99d05cb8156e5bf 364 PRINTS PR00096 Glutamine amidotransferase superfamily signature 325 338 3.7E-11 T 28-03-2018 ALX04_RS07825 d93c2a73ca7be1e8e99d05cb8156e5bf 364 PRINTS PR00096 Glutamine amidotransferase superfamily signature 212 221 3.7E-11 T 28-03-2018 ALX04_RS07825 d93c2a73ca7be1e8e99d05cb8156e5bf 364 Hamap MF_01209 Carbamoyl-phosphate synthase small chain [carA]. 1 354 47.412 T 28-03-2018 IPR006274 Carbamoyl-phosphate synthase, small subunit GO:0004088|GO:0006207|GO:0006541 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 ALX04_RS07825 d93c2a73ca7be1e8e99d05cb8156e5bf 364 Gene3D G3DSA:3.40.50.880 138 355 1.1E-53 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like ALX04_RS07825 d93c2a73ca7be1e8e99d05cb8156e5bf 364 TIGRFAM TIGR01368 CPSaseIIsmall: carbamoyl-phosphate synthase, small subunit 4 351 2.4E-150 T 28-03-2018 IPR006274 Carbamoyl-phosphate synthase, small subunit GO:0004088|GO:0006207|GO:0006541 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 ALX04_RS07825 d93c2a73ca7be1e8e99d05cb8156e5bf 364 Pfam PF00988 Carbamoyl-phosphate synthase small chain, CPSase domain 3 130 1.3E-52 T 28-03-2018 IPR002474 Carbamoyl-phosphate synthase small subunit, N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 ALX04_RS07825 d93c2a73ca7be1e8e99d05cb8156e5bf 364 Gene3D G3DSA:3.50.30.20 1 137 1.5E-58 T 28-03-2018 IPR002474 Carbamoyl-phosphate synthase small subunit, N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 ALX04_RS07825 d93c2a73ca7be1e8e99d05cb8156e5bf 364 Pfam PF00117 Glutamine amidotransferase class-I 172 348 9.3E-45 T 28-03-2018 IPR017926 Glutamine amidotransferase ALX04_RS07825 d93c2a73ca7be1e8e99d05cb8156e5bf 364 SUPERFAMILY SSF52317 142 352 1.12E-57 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like ALX04_RS07825 d93c2a73ca7be1e8e99d05cb8156e5bf 364 SMART SM01097 1 131 1.9E-88 T 28-03-2018 IPR002474 Carbamoyl-phosphate synthase small subunit, N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 ALX04_RS07825 d93c2a73ca7be1e8e99d05cb8156e5bf 364 PRINTS PR00097 Anthranilate synthase component II signature 325 338 4.7E-6 T 28-03-2018 ALX04_RS07825 d93c2a73ca7be1e8e99d05cb8156e5bf 364 PRINTS PR00097 Anthranilate synthase component II signature 212 221 4.7E-6 T 28-03-2018 ALX04_RS07825 d93c2a73ca7be1e8e99d05cb8156e5bf 364 PRINTS PR00097 Anthranilate synthase component II signature 239 250 4.7E-6 T 28-03-2018 ALX04_RS07825 d93c2a73ca7be1e8e99d05cb8156e5bf 364 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 239 255 1.2E-37 T 28-03-2018 ALX04_RS07825 d93c2a73ca7be1e8e99d05cb8156e5bf 364 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 256 273 1.2E-37 T 28-03-2018 ALX04_RS07825 d93c2a73ca7be1e8e99d05cb8156e5bf 364 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 170 184 1.2E-37 T 28-03-2018 ALX04_RS07825 d93c2a73ca7be1e8e99d05cb8156e5bf 364 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 209 223 1.2E-37 T 28-03-2018 ALX04_RS07825 d93c2a73ca7be1e8e99d05cb8156e5bf 364 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 281 292 1.2E-37 T 28-03-2018 ALX04_RS07825 d93c2a73ca7be1e8e99d05cb8156e5bf 364 SUPERFAMILY SSF52021 1 140 4.05E-56 T 28-03-2018 IPR002474 Carbamoyl-phosphate synthase small subunit, N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 ALX04_RS06435 700fe269b9ed32f2c17c4610755013c2 70 Pfam PF00137 ATP synthase subunit C 4 66 4.2E-14 T 28-03-2018 IPR002379 V-ATPase proteolipid subunit C-like domain GO:0015078|GO:0015991|GO:0033177 ALX04_RS06435 700fe269b9ed32f2c17c4610755013c2 70 SUPERFAMILY SSF81333 3 69 4.45E-19 T 28-03-2018 IPR002379 V-ATPase proteolipid subunit C-like domain GO:0015078|GO:0015991|GO:0033177 ALX04_RS06435 700fe269b9ed32f2c17c4610755013c2 70 ProSitePatterns PS00605 ATP synthase c subunit signature. 33 54 - T 28-03-2018 IPR020537 ATP synthase, F0 complex, subunit C, DCCD-binding site Reactome: R-HSA-163210|Reactome: R-HSA-8949613 ALX04_RS06435 700fe269b9ed32f2c17c4610755013c2 70 TIGRFAM TIGR01260 ATP_synt_c: ATP synthase F0, C subunit 13 68 4.5E-26 T 28-03-2018 IPR005953 ATP synthase, F0 complex, subunit C, bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 ALX04_RS06435 700fe269b9ed32f2c17c4610755013c2 70 Gene3D G3DSA:1.20.20.10 1 69 1.8E-18 T 28-03-2018 IPR002379 V-ATPase proteolipid subunit C-like domain GO:0015078|GO:0015991|GO:0033177 ALX04_RS06435 700fe269b9ed32f2c17c4610755013c2 70 PRINTS PR00124 ATP synthase C subunit signature 26 41 6.8E-15 T 28-03-2018 IPR000454 ATP synthase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 ALX04_RS06435 700fe269b9ed32f2c17c4610755013c2 70 PRINTS PR00124 ATP synthase C subunit signature 43 68 6.8E-15 T 28-03-2018 IPR000454 ATP synthase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 ALX04_RS06435 700fe269b9ed32f2c17c4610755013c2 70 PRINTS PR00124 ATP synthase C subunit signature 5 24 6.8E-15 T 28-03-2018 IPR000454 ATP synthase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 ALX04_RS06435 700fe269b9ed32f2c17c4610755013c2 70 Hamap MF_01396 ATP synthase subunit c [atpH]. 3 68 15.228 T 28-03-2018 IPR000454 ATP synthase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 ALX04_RS12635 46ec0239cd5a58879d5ec1c40dda12b6 364 SUPERFAMILY SSF51445 4 244 4.63E-86 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily ALX04_RS12635 46ec0239cd5a58879d5ec1c40dda12b6 364 SUPERFAMILY SSF50891 247 360 5.31E-32 T 28-03-2018 IPR029000 Cyclophilin-like domain ALX04_RS12635 46ec0239cd5a58879d5ec1c40dda12b6 364 Gene3D G3DSA:2.40.100.10 246 359 2.5E-30 T 28-03-2018 IPR029000 Cyclophilin-like domain ALX04_RS12635 46ec0239cd5a58879d5ec1c40dda12b6 364 Pfam PF05913 Bacterial protein of unknown function (DUF871) 6 360 1.7E-125 T 28-03-2018 IPR008589 Protein of unknown function DUF871, prokaryotic ALX04_RS12635 46ec0239cd5a58879d5ec1c40dda12b6 364 Gene3D G3DSA:3.20.20.70 5 240 1.4E-85 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 ALX04_RS14355 c5dd85c0497e4270dde9d18ae2f32434 168 Pfam PF14437 MafB19-like deaminase 6 151 2.5E-38 T 28-03-2018 IPR028883 tRNA-specific adenosine deaminase GO:0002100|GO:0008251 Reactome: R-HSA-6782315 ALX04_RS14355 c5dd85c0497e4270dde9d18ae2f32434 168 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 55 92 - T 28-03-2018 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 ALX04_RS14355 c5dd85c0497e4270dde9d18ae2f32434 168 Gene3D G3DSA:3.40.140.10 1 161 2.0E-47 T 28-03-2018 ALX04_RS14355 c5dd85c0497e4270dde9d18ae2f32434 168 SUPERFAMILY SSF53927 5 155 2.51E-51 T 28-03-2018 IPR016193 Cytidine deaminase-like GO:0003824 ALX04_RS14355 c5dd85c0497e4270dde9d18ae2f32434 168 Hamap MF_00972 tRNA-specific adenosine deaminase [tadA]. 10 151 44.989 T 28-03-2018 IPR028883 tRNA-specific adenosine deaminase GO:0002100|GO:0008251 Reactome: R-HSA-6782315 ALX04_RS04610 d03399c379b2403dff1582847c70aa7a 1437 Gene3D G3DSA:3.20.20.140 335 762 3.0E-61 T 28-03-2018 ALX04_RS04610 d03399c379b2403dff1582847c70aa7a 1437 Pfam PF00929 Exonuclease 423 574 2.1E-32 T 28-03-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III ALX04_RS04610 d03399c379b2403dff1582847c70aa7a 1437 Pfam PF11490 DNA polymerase III polC-type N-terminus II 91 205 9.3E-32 T 28-03-2018 IPR024754 DNA polymerase III polC-like, N-terminal domain II KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 ALX04_RS04610 d03399c379b2403dff1582847c70aa7a 1437 SMART SM00479 421 587 3.0E-36 T 28-03-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III ALX04_RS04610 d03399c379b2403dff1582847c70aa7a 1437 Pfam PF07733 Bacterial DNA polymerase III alpha subunit 825 1234 2.3E-89 T 28-03-2018 IPR011708 Bacterial DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 ALX04_RS04610 d03399c379b2403dff1582847c70aa7a 1437 SUPERFAMILY SSF53098 421 876 5.06E-99 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 ALX04_RS04610 d03399c379b2403dff1582847c70aa7a 1437 Pfam PF14579 Helix-hairpin-helix motif 1353 1429 3.0E-7 T 28-03-2018 IPR029460 DNA polymerase, helix-hairpin-helix motif KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 ALX04_RS04610 d03399c379b2403dff1582847c70aa7a 1437 Pfam PF02811 PHP domain 337 695 3.6E-51 T 28-03-2018 IPR004013 PHP domain GO:0003824 ALX04_RS04610 d03399c379b2403dff1582847c70aa7a 1437 SMART SM00481 336 403 9.4E-27 T 28-03-2018 IPR003141 Polymerase/histidinol phosphatase, N-terminal ALX04_RS04610 d03399c379b2403dff1582847c70aa7a 1437 SUPERFAMILY SSF50249 236 315 1.97E-10 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold ALX04_RS04610 d03399c379b2403dff1582847c70aa7a 1437 TIGRFAM TIGR00573 dnaq: exonuclease, DNA polymerase III, epsilon subunit family 417 634 7.6E-36 T 28-03-2018 IPR006054 DNA polymerase III epsilon subunit, exonuclease domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 ALX04_RS04610 d03399c379b2403dff1582847c70aa7a 1437 Hamap MF_00356 DNA polymerase III PolC-type [polC]. 1 1437 433.954 T 28-03-2018 IPR006308 DNA polymerase III, alpha subunit, Gram-positive type GO:0003677|GO:0003887|GO:0005737|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 ALX04_RS04610 d03399c379b2403dff1582847c70aa7a 1437 Pfam PF14480 DNA polymerase III polC-type N-terminus I 8 77 7.7E-20 T 28-03-2018 IPR028112 DNA polymerase III polC-type, N-terminal domain I KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 ALX04_RS04610 d03399c379b2403dff1582847c70aa7a 1437 Gene3D G3DSA:2.40.50.140 220 321 9.2E-18 T 28-03-2018 ALX04_RS04610 d03399c379b2403dff1582847c70aa7a 1437 TIGRFAM TIGR01405 polC_Gram_pos: DNA polymerase III, alpha subunit, Gram-positive type 231 1437 0.0 T 28-03-2018 IPR006308 DNA polymerase III, alpha subunit, Gram-positive type GO:0003677|GO:0003887|GO:0005737|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 ALX04_RS05280 30434c34db380e060b6ee1171e079744 100 Hamap MF_01126 UPF0298 protein . 4 81 21.179 T 28-03-2018 IPR016979 Protein of unknown function DUF2129 ALX04_RS05280 30434c34db380e060b6ee1171e079744 100 Pfam PF09902 Uncharacterized protein conserved in bacteria (DUF2129) 8 77 3.0E-28 T 28-03-2018 IPR016979 Protein of unknown function DUF2129 ALX04_RS05280 30434c34db380e060b6ee1171e079744 100 PIRSF PIRSF031653 2 94 8.9E-34 T 28-03-2018 IPR016979 Protein of unknown function DUF2129 ALX04_RS09035 d8a6d9e4ce7b9267a3c039fd6585721d 585 SUPERFAMILY SSF90123 24 330 7.72E-73 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 ALX04_RS09035 d8a6d9e4ce7b9267a3c039fd6585721d 585 Pfam PF00005 ABC transporter 362 512 3.2E-31 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 ALX04_RS09035 d8a6d9e4ce7b9267a3c039fd6585721d 585 Gene3D G3DSA:1.20.1560.10 9 333 5.3E-69 T 28-03-2018 ALX04_RS09035 d8a6d9e4ce7b9267a3c039fd6585721d 585 ProSitePatterns PS00211 ABC transporters family signature. 484 498 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 ALX04_RS09035 d8a6d9e4ce7b9267a3c039fd6585721d 585 Gene3D G3DSA:3.40.50.300 343 579 3.4E-69 T 28-03-2018 ALX04_RS09035 d8a6d9e4ce7b9267a3c039fd6585721d 585 Pfam PF00664 ABC transporter transmembrane region 36 301 2.5E-48 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 ALX04_RS09035 d8a6d9e4ce7b9267a3c039fd6585721d 585 SUPERFAMILY SSF52540 341 583 2.11E-84 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase ALX04_RS09035 d8a6d9e4ce7b9267a3c039fd6585721d 585 SMART SM00382 371 558 3.0E-12 T 28-03-2018 IPR003593 AAA+ ATPase domain ALX04_RS04365 4177df115aa81599719f520ec954dfd8 159 Gene3D G3DSA:3.40.390.30 1 159 6.9E-45 T 28-03-2018 IPR023091 Metalloprotease catalytic domain, predicted GO:0004222 ALX04_RS04365 4177df115aa81599719f520ec954dfd8 159 TIGRFAM TIGR00043 TIGR00043: rRNA maturation RNase YbeY 39 156 4.2E-37 T 28-03-2018 IPR002036 Endoribonuclease YbeY GO:0004222|GO:0006364 ALX04_RS04365 4177df115aa81599719f520ec954dfd8 159 Hamap MF_00009 Endoribonuclease YbeY [ybeY]. 2 159 21.928 T 28-03-2018 IPR002036 Endoribonuclease YbeY GO:0004222|GO:0006364 ALX04_RS04365 4177df115aa81599719f520ec954dfd8 159 ProSitePatterns PS01306 Uncharacterized protein family UPF0054 signature. 125 135 - T 28-03-2018 IPR020549 Endoribonuclease YbeY, conserved site ALX04_RS04365 4177df115aa81599719f520ec954dfd8 159 Pfam PF02130 Uncharacterized protein family UPF0054 16 154 2.7E-42 T 28-03-2018 IPR002036 Endoribonuclease YbeY GO:0004222|GO:0006364 ALX04_RS04365 4177df115aa81599719f520ec954dfd8 159 SUPERFAMILY SSF55486 14 158 2.27E-40 T 28-03-2018 ALX04_RS10000 df7c9d4f571ffa9d9be492b42d874afd 361 Pfam PF02698 DUF218 domain 178 328 8.1E-29 T 28-03-2018 IPR003848 Domain of unknown function DUF218 ALX04_RS10000 df7c9d4f571ffa9d9be492b42d874afd 361 Gene3D G3DSA:3.40.50.620 171 315 8.0E-30 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold ALX04_RS02580 ade92f6d5f5a126a11ef38f1a82409b5 49 Pfam PF00471 Ribosomal protein L33 3 49 8.8E-21 T 28-03-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 ALX04_RS02580 ade92f6d5f5a126a11ef38f1a82409b5 49 ProSitePatterns PS00582 Ribosomal protein L33 signature. 17 36 - T 28-03-2018 IPR018264 Ribosomal protein L33, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 ALX04_RS02580 ade92f6d5f5a126a11ef38f1a82409b5 49 TIGRFAM TIGR01023 rpmG_bact: ribosomal protein bL33 3 49 2.5E-20 T 28-03-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 ALX04_RS02580 ade92f6d5f5a126a11ef38f1a82409b5 49 Hamap MF_00294 50S ribosomal protein L33 [rpmG]. 1 49 18.216 T 28-03-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 ALX04_RS02580 ade92f6d5f5a126a11ef38f1a82409b5 49 SUPERFAMILY SSF57829 1 49 5.8E-18 T 28-03-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 ALX04_RS00385 5713df366deeb29f7412677c5c18c09f 207 Pfam PF00573 Ribosomal protein L4/L1 family 17 204 4.0E-68 T 28-03-2018 IPR002136 Ribosomal protein L4/L1e GO:0003735|GO:0005840|GO:0006412 ALX04_RS00385 5713df366deeb29f7412677c5c18c09f 207 Hamap MF_01328_B 50S ribosomal protein L4 [rplD]. 9 207 35.927 T 28-03-2018 IPR013005 50S ribosomal protein uL4 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 ALX04_RS00385 5713df366deeb29f7412677c5c18c09f 207 SUPERFAMILY SSF52166 1 206 1.07E-79 T 28-03-2018 IPR023574 Ribosomal protein L4 domain GO:0003735|GO:0005840|GO:0006412 ALX04_RS00385 5713df366deeb29f7412677c5c18c09f 207 Gene3D G3DSA:3.40.1370.10 147 205 2.1E-14 T 28-03-2018 IPR023574 Ribosomal protein L4 domain GO:0003735|GO:0005840|GO:0006412 ALX04_RS00385 5713df366deeb29f7412677c5c18c09f 207 Gene3D G3DSA:3.40.1370.10 2 146 4.2E-55 T 28-03-2018 IPR023574 Ribosomal protein L4 domain GO:0003735|GO:0005840|GO:0006412 ALX04_RS00385 5713df366deeb29f7412677c5c18c09f 207 TIGRFAM TIGR03953 rplD_bact: 50S ribosomal protein uL4 17 204 1.2E-78 T 28-03-2018 IPR013005 50S ribosomal protein uL4 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 ALX04_RS14655 2fe52009b95cbb14203642841ef96b7a 452 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 2 305 2.8E-57 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ALX04_RS14655 2fe52009b95cbb14203642841ef96b7a 452 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 2 24 1.7E-9 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 ALX04_RS14655 2fe52009b95cbb14203642841ef96b7a 452 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 105 113 1.7E-9 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 ALX04_RS14655 2fe52009b95cbb14203642841ef96b7a 452 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 236 257 1.7E-9 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 ALX04_RS14655 2fe52009b95cbb14203642841ef96b7a 452 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 145 169 1.7E-9 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 ALX04_RS14655 2fe52009b95cbb14203642841ef96b7a 452 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 270 288 1.7E-9 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 ALX04_RS14655 2fe52009b95cbb14203642841ef96b7a 452 Gene3D G3DSA:3.50.50.60 243 326 2.1E-10 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ALX04_RS14655 2fe52009b95cbb14203642841ef96b7a 452 Gene3D G3DSA:3.50.50.60 104 242 3.9E-30 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ALX04_RS14655 2fe52009b95cbb14203642841ef96b7a 452 Gene3D G3DSA:3.30.390.30 327 451 3.5E-21 T 28-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 ALX04_RS14655 2fe52009b95cbb14203642841ef96b7a 452 SUPERFAMILY SSF55424 321 444 2.06E-32 T 28-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 ALX04_RS14655 2fe52009b95cbb14203642841ef96b7a 452 SUPERFAMILY SSF51905 1 314 1.59E-38 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ALX04_RS14655 2fe52009b95cbb14203642841ef96b7a 452 Gene3D G3DSA:3.50.50.60 1 103 6.1E-8 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ALX04_RS14655 2fe52009b95cbb14203642841ef96b7a 452 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 329 431 7.4E-13 T 28-03-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 ALX04_RS14655 2fe52009b95cbb14203642841ef96b7a 452 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 3 22 1.7E-18 T 28-03-2018 ALX04_RS14655 2fe52009b95cbb14203642841ef96b7a 452 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 234 250 1.7E-18 T 28-03-2018 ALX04_RS14655 2fe52009b95cbb14203642841ef96b7a 452 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 104 122 1.7E-18 T 28-03-2018 ALX04_RS14655 2fe52009b95cbb14203642841ef96b7a 452 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 149 167 1.7E-18 T 28-03-2018 ALX04_RS14655 2fe52009b95cbb14203642841ef96b7a 452 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 260 282 1.7E-18 T 28-03-2018 ALX04_RS11890 dbbce71c8743ca72338ee79db384fb7a 123 Pfam PF12395 Protein of unknown function 33 119 5.8E-16 T 28-03-2018 IPR022123 Protein of unknown function DUF3658 ALX04_RS13050 caaa8ce93a7c34b65631a16952f63d2e 187 PIRSF PIRSF016661 1 184 8.7E-36 T 28-03-2018 IPR003784 BioY protein GO:0005886|GO:0015225|GO:0015878 ALX04_RS13050 caaa8ce93a7c34b65631a16952f63d2e 187 Pfam PF02632 BioY family 33 178 1.8E-31 T 28-03-2018 IPR003784 BioY protein GO:0005886|GO:0015225|GO:0015878 ALX04_RS06410 94ff0aa89a0e3e273a551705c6c9c752 467 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 337 346 - T 28-03-2018 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 ALX04_RS06410 94ff0aa89a0e3e273a551705c6c9c752 467 SUPERFAMILY SSF47917 349 464 9.68E-52 T 28-03-2018 ALX04_RS06410 94ff0aa89a0e3e273a551705c6c9c752 467 SUPERFAMILY SSF52540 79 351 3.08E-92 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase ALX04_RS06410 94ff0aa89a0e3e273a551705c6c9c752 467 SUPERFAMILY SSF50615 1 76 2.09E-23 T 28-03-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 ALX04_RS06410 94ff0aa89a0e3e273a551705c6c9c752 467 Gene3D G3DSA:2.40.10.170 1 77 1.0E-28 T 28-03-2018 ALX04_RS06410 94ff0aa89a0e3e273a551705c6c9c752 467 TIGRFAM TIGR01039 atpD: ATP synthase F1, beta subunit 3 464 3.2E-251 T 28-03-2018 IPR005722 ATP synthase, F1 complex, beta subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-2151201|Reactome: R-HSA-8949613 ALX04_RS06410 94ff0aa89a0e3e273a551705c6c9c752 467 Hamap MF_01347 ATP synthase subunit beta [atpB]. 1 464 57.171 T 28-03-2018 IPR005722 ATP synthase, F1 complex, beta subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-2151201|Reactome: R-HSA-8949613 ALX04_RS06410 94ff0aa89a0e3e273a551705c6c9c752 467 Gene3D G3DSA:1.10.1140.10 352 462 3.0E-41 T 28-03-2018 IPR024034 ATPase, F1/V1 complex, beta/alpha subunit, C-terminal KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 ALX04_RS06410 94ff0aa89a0e3e273a551705c6c9c752 467 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 133 346 2.2E-68 T 28-03-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 ALX04_RS06410 94ff0aa89a0e3e273a551705c6c9c752 467 SMART SM00382 145 330 6.8E-8 T 28-03-2018 IPR003593 AAA+ ATPase domain ALX04_RS06410 94ff0aa89a0e3e273a551705c6c9c752 467 Gene3D G3DSA:3.40.50.300 78 351 1.3E-91 T 28-03-2018 ALX04_RS06410 94ff0aa89a0e3e273a551705c6c9c752 467 Pfam PF02874 ATP synthase alpha/beta family, beta-barrel domain 6 75 3.5E-22 T 28-03-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 ALX04_RS10660 08440c142885dbc6525653f353fbdba9 516 Pfam PF00149 Calcineurin-like phosphoesterase 5 237 8.0E-9 T 28-03-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 ALX04_RS10660 08440c142885dbc6525653f353fbdba9 516 SUPERFAMILY SSF55816 305 513 1.83E-42 T 28-03-2018 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 ALX04_RS10660 08440c142885dbc6525653f353fbdba9 516 PRINTS PR01607 Apyrase family signature 220 243 1.4E-19 T 28-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 ALX04_RS10660 08440c142885dbc6525653f353fbdba9 516 PRINTS PR01607 Apyrase family signature 452 471 1.4E-19 T 28-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 ALX04_RS10660 08440c142885dbc6525653f353fbdba9 516 PRINTS PR01607 Apyrase family signature 1 19 1.4E-19 T 28-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 ALX04_RS10660 08440c142885dbc6525653f353fbdba9 516 PRINTS PR01607 Apyrase family signature 185 202 1.4E-19 T 28-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 ALX04_RS10660 08440c142885dbc6525653f353fbdba9 516 PRINTS PR01607 Apyrase family signature 246 266 1.4E-19 T 28-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 ALX04_RS10660 08440c142885dbc6525653f353fbdba9 516 PRINTS PR01607 Apyrase family signature 363 386 1.4E-19 T 28-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 ALX04_RS10660 08440c142885dbc6525653f353fbdba9 516 Gene3D G3DSA:3.90.780.10 308 516 7.7E-40 T 28-03-2018 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 ALX04_RS10660 08440c142885dbc6525653f353fbdba9 516 Gene3D G3DSA:3.60.21.10 1 307 5.4E-61 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like ALX04_RS10660 08440c142885dbc6525653f353fbdba9 516 SUPERFAMILY SSF56300 2 306 4.86E-67 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like ALX04_RS10660 08440c142885dbc6525653f353fbdba9 516 Pfam PF02872 5'-nucleotidase, C-terminal domain 320 478 1.1E-24 T 28-03-2018 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 ALX04_RS02135 7b8ef7cc1bd912fb5588eee8cef9e13f 362 Gene3D G3DSA:3.90.550.10 3 236 1.4E-17 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases ALX04_RS02135 7b8ef7cc1bd912fb5588eee8cef9e13f 362 SUPERFAMILY SSF53448 3 254 4.56E-28 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases ALX04_RS02135 7b8ef7cc1bd912fb5588eee8cef9e13f 362 Pfam PF00535 Glycosyl transferase family 2 6 139 2.1E-17 T 28-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 ALX04_RS02135 7b8ef7cc1bd912fb5588eee8cef9e13f 362 Pfam PF04138 GtrA-like protein 233 354 5.1E-11 T 28-03-2018 IPR007267 GtrA-like protein GO:0000271|GO:0006810|GO:0016021 ALX04_RS15195 9aa5ca1de492db49f9d633ffcb7844e1 146 SMART SM00347 30 138 9.4E-11 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 ALX04_RS15195 9aa5ca1de492db49f9d633ffcb7844e1 146 Gene3D G3DSA:1.10.10.10 1 146 1.2E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS15195 9aa5ca1de492db49f9d633ffcb7844e1 146 Pfam PF01047 MarR family 37 97 1.1E-14 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 ALX04_RS15195 9aa5ca1de492db49f9d633ffcb7844e1 146 SUPERFAMILY SSF46785 3 144 2.58E-30 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS06325 d1e73e7ea08cdd70f358f934f85fdbba 298 SUPERFAMILY SSF48452 84 267 1.02E-6 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 ALX04_RS06325 d1e73e7ea08cdd70f358f934f85fdbba 298 Gene3D G3DSA:1.10.3100.10 1 130 7.6E-17 T 28-03-2018 IPR027910 YdiL-like domain ALX04_RS06325 d1e73e7ea08cdd70f358f934f85fdbba 298 Gene3D G3DSA:1.25.40.10 139 286 5.2E-4 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 ALX04_RS06325 d1e73e7ea08cdd70f358f934f85fdbba 298 SMART SM00530 7 61 1.7E-11 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 ALX04_RS06325 d1e73e7ea08cdd70f358f934f85fdbba 298 Pfam PF01381 Helix-turn-helix 8 60 1.8E-11 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 ALX04_RS06325 d1e73e7ea08cdd70f358f934f85fdbba 298 SUPERFAMILY SSF47413 4 62 5.91E-14 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 ALX04_RS15990 914aec772a7e33ac727bcc001a760b97 220 SUPERFAMILY SSF109604 3 216 9.42E-56 T 28-03-2018 ALX04_RS15990 914aec772a7e33ac727bcc001a760b97 220 Gene3D G3DSA:1.10.3210.10 1 217 8.3E-14 T 28-03-2018 ALX04_RS15990 914aec772a7e33ac727bcc001a760b97 220 SMART SM00471 18 139 1.5E-4 T 28-03-2018 IPR003607 HD/PDEase domain ALX04_RS15990 914aec772a7e33ac727bcc001a760b97 220 Pfam PF01966 HD domain 25 129 6.6E-5 T 28-03-2018 IPR006674 HD domain ALX04_RS08430 2ede78ac66d2f9a1c499e11101c34265 275 Gene3D G3DSA:3.40.190.10 177 245 1.8E-7 T 28-03-2018 ALX04_RS08430 2ede78ac66d2f9a1c499e11101c34265 275 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 28 38 1.7E-7 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 ALX04_RS08430 2ede78ac66d2f9a1c499e11101c34265 275 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 38 49 1.7E-7 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 ALX04_RS08430 2ede78ac66d2f9a1c499e11101c34265 275 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 17 28 1.7E-7 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 ALX04_RS08430 2ede78ac66d2f9a1c499e11101c34265 275 Pfam PF03466 LysR substrate binding domain 93 240 1.8E-18 T 28-03-2018 IPR005119 LysR, substrate-binding ALX04_RS08430 2ede78ac66d2f9a1c499e11101c34265 275 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 2 62 2.6E-20 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 ALX04_RS08430 2ede78ac66d2f9a1c499e11101c34265 275 Gene3D G3DSA:3.40.190.10 86 176 7.0E-11 T 28-03-2018 ALX04_RS08430 2ede78ac66d2f9a1c499e11101c34265 275 SUPERFAMILY SSF46785 3 84 1.13E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS08430 2ede78ac66d2f9a1c499e11101c34265 275 SUPERFAMILY SSF53850 92 239 7.6E-18 T 28-03-2018 ALX04_RS08430 2ede78ac66d2f9a1c499e11101c34265 275 Gene3D G3DSA:1.10.10.10 1 83 2.0E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS02910 e66dd486f632446fa77df3d97fd2c012 118 PIRSF PIRSF002191 1 118 4.4E-50 T 28-03-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 ALX04_RS02910 e66dd486f632446fa77df3d97fd2c012 118 Hamap MF_00402 50S ribosomal protein L19 [rplS]. 4 116 31.985 T 28-03-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 ALX04_RS02910 e66dd486f632446fa77df3d97fd2c012 118 SUPERFAMILY SSF50104 2 117 6.22E-47 T 28-03-2018 IPR008991 Translation protein SH3-like domain ALX04_RS02910 e66dd486f632446fa77df3d97fd2c012 118 Pfam PF01245 Ribosomal protein L19 6 114 1.0E-51 T 28-03-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 ALX04_RS02910 e66dd486f632446fa77df3d97fd2c012 118 TIGRFAM TIGR01024 rplS_bact: ribosomal protein bL19 5 115 2.4E-49 T 28-03-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 ALX04_RS02910 e66dd486f632446fa77df3d97fd2c012 118 ProSitePatterns PS01015 Ribosomal protein L19 signature. 88 103 - T 28-03-2018 IPR018257 Ribosomal protein L19, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 ALX04_RS02910 e66dd486f632446fa77df3d97fd2c012 118 PRINTS PR00061 Ribosomal protein L19 signature 6 35 1.1E-42 T 28-03-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 ALX04_RS02910 e66dd486f632446fa77df3d97fd2c012 118 PRINTS PR00061 Ribosomal protein L19 signature 36 65 1.1E-42 T 28-03-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 ALX04_RS02910 e66dd486f632446fa77df3d97fd2c012 118 PRINTS PR00061 Ribosomal protein L19 signature 90 115 1.1E-42 T 28-03-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 ALX04_RS07775 6b875348f8277376f687c1b5747bfbe7 298 Pfam PF03466 LysR substrate binding domain 89 290 2.0E-25 T 28-03-2018 IPR005119 LysR, substrate-binding ALX04_RS07775 6b875348f8277376f687c1b5747bfbe7 298 Gene3D G3DSA:3.40.190.10 91 176 8.7E-6 T 28-03-2018 ALX04_RS07775 6b875348f8277376f687c1b5747bfbe7 298 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 5.7E-6 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 ALX04_RS07775 6b875348f8277376f687c1b5747bfbe7 298 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 5.7E-6 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 ALX04_RS07775 6b875348f8277376f687c1b5747bfbe7 298 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 5.7E-6 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 ALX04_RS07775 6b875348f8277376f687c1b5747bfbe7 298 SUPERFAMILY SSF53850 90 293 1.88E-24 T 28-03-2018 ALX04_RS07775 6b875348f8277376f687c1b5747bfbe7 298 Gene3D G3DSA:3.40.190.10 177 263 5.6E-15 T 28-03-2018 ALX04_RS07775 6b875348f8277376f687c1b5747bfbe7 298 SUPERFAMILY SSF46785 1 86 3.38E-14 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS07775 6b875348f8277376f687c1b5747bfbe7 298 Gene3D G3DSA:1.10.10.10 1 90 3.9E-12 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS07775 6b875348f8277376f687c1b5747bfbe7 298 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 63 2.4E-12 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 ALX04_RS04820 e7f58bae801d8d74ef2fce63fab77a69 124 Pfam PF05657 Protein of unknown function (DUF806) 3 122 1.2E-44 T 28-03-2018 IPR008524 Protein of unknown function DUF806 ALX04_RS00395 d1a6e4ec5621d3db14806f1869b90fe2 279 Gene3D G3DSA:2.30.30.30 119 195 5.5E-34 T 28-03-2018 IPR014722 Ribosomal protein L2 domain 2 ALX04_RS00395 d1a6e4ec5621d3db14806f1869b90fe2 279 SUPERFAMILY SSF50104 126 272 6.62E-58 T 28-03-2018 IPR008991 Translation protein SH3-like domain ALX04_RS00395 d1a6e4ec5621d3db14806f1869b90fe2 279 SUPERFAMILY SSF50249 3 125 2.06E-48 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold ALX04_RS00395 d1a6e4ec5621d3db14806f1869b90fe2 279 Hamap MF_01320_B 50S ribosomal protein L2 [rplB]. 1 275 46.579 T 28-03-2018 IPR005880 Ribosomal protein L2, bacterial/organellar-type GO:0003723|GO:0003735|GO:0006412|GO:0015934|GO:0016740 ALX04_RS00395 d1a6e4ec5621d3db14806f1869b90fe2 279 Gene3D G3DSA:4.10.950.10 197 275 9.8E-31 T 28-03-2018 IPR014726 Ribosomal protein L2, domain 3 ALX04_RS00395 d1a6e4ec5621d3db14806f1869b90fe2 279 SMART SM01383 42 118 1.1E-45 T 28-03-2018 IPR002171 Ribosomal protein L2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 ALX04_RS00395 d1a6e4ec5621d3db14806f1869b90fe2 279 Gene3D G3DSA:2.40.50.140 1 114 5.1E-47 T 28-03-2018 ALX04_RS00395 d1a6e4ec5621d3db14806f1869b90fe2 279 SMART SM01382 124 253 7.0E-91 T 28-03-2018 IPR022669 Ribosomal protein L2, C-terminal GO:0003735|GO:0005840|GO:0006412 ALX04_RS00395 d1a6e4ec5621d3db14806f1869b90fe2 279 TIGRFAM TIGR01171 rplB_bact: ribosomal protein uL2 3 275 1.3E-132 T 28-03-2018 IPR005880 Ribosomal protein L2, bacterial/organellar-type GO:0003723|GO:0003735|GO:0006412|GO:0015934|GO:0016740 ALX04_RS00395 d1a6e4ec5621d3db14806f1869b90fe2 279 PIRSF PIRSF002158 3 276 1.8E-95 T 28-03-2018 IPR002171 Ribosomal protein L2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 ALX04_RS00395 d1a6e4ec5621d3db14806f1869b90fe2 279 Pfam PF00181 Ribosomal Proteins L2, RNA binding domain 42 117 4.2E-31 T 28-03-2018 IPR022666 Ribosomal Proteins L2, RNA binding domain GO:0003735|GO:0005622|GO:0005840|GO:0006412 ALX04_RS00395 d1a6e4ec5621d3db14806f1869b90fe2 279 ProSitePatterns PS00467 Ribosomal protein L2 signature. 218 229 - T 28-03-2018 IPR022671 Ribosomal protein L2, conserved site GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 ALX04_RS00395 d1a6e4ec5621d3db14806f1869b90fe2 279 Pfam PF03947 Ribosomal Proteins L2, C-terminal domain 125 251 9.0E-55 T 28-03-2018 IPR022669 Ribosomal protein L2, C-terminal GO:0003735|GO:0005840|GO:0006412 ALX04_RS13795 d2ba040dd47a17b027232702ac751828 212 Gene3D G3DSA:3.20.20.70 3 204 3.7E-16 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 ALX04_RS13795 d2ba040dd47a17b027232702ac751828 212 PIRSF PIRSF035040 1 212 1.1E-98 T 28-03-2018 IPR017036 Uncharacterised conserved protein UCP035040, CBS-type ALX04_RS13795 d2ba040dd47a17b027232702ac751828 212 Pfam PF00571 CBS domain 11 57 1.3E-5 T 28-03-2018 IPR000644 CBS domain ALX04_RS13795 d2ba040dd47a17b027232702ac751828 212 SUPERFAMILY SSF54631 3 124 8.04E-21 T 28-03-2018 ALX04_RS10410 b2c4ac35acafe690f1d66a3156a51380 174 SUPERFAMILY SSF54197 2 128 3.83E-32 T 28-03-2018 IPR011146 HIT-like domain GO:0003824 ALX04_RS10410 b2c4ac35acafe690f1d66a3156a51380 174 Gene3D G3DSA:3.30.428.10 11 166 7.6E-19 T 28-03-2018 IPR011146 HIT-like domain GO:0003824 ALX04_RS10410 b2c4ac35acafe690f1d66a3156a51380 174 Pfam PF01230 HIT domain 22 106 2.6E-6 T 28-03-2018 IPR001310 Histidine triad (HIT) protein ALX04_RS13025 14fba8981e0fa027a509d40c2e4ddbbe 438 Pfam PF13347 MFS/sugar transport protein 14 428 4.0E-70 T 28-03-2018 ALX04_RS13025 14fba8981e0fa027a509d40c2e4ddbbe 438 Gene3D G3DSA:1.20.1250.20 216 433 5.6E-12 T 28-03-2018 ALX04_RS13025 14fba8981e0fa027a509d40c2e4ddbbe 438 Gene3D G3DSA:1.20.1250.20 4 209 8.8E-15 T 28-03-2018 ALX04_RS13025 14fba8981e0fa027a509d40c2e4ddbbe 438 TIGRFAM TIGR00792 gph: sugar (Glycoside-Pentoside-Hexuronide) transporter 12 428 4.6E-106 T 28-03-2018 IPR001927 Sodium:galactoside symporter GO:0005215|GO:0006814|GO:0016020 ALX04_RS13025 14fba8981e0fa027a509d40c2e4ddbbe 438 SUPERFAMILY SSF103473 9 428 3.31E-28 T 28-03-2018 IPR020846 Major facilitator superfamily domain ALX04_RS08035 c3bb2f481b98bad761e9e90617ecc6d5 398 Gene3D G3DSA:3.40.640.10 46 281 4.7E-32 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 ALX04_RS08035 c3bb2f481b98bad761e9e90617ecc6d5 398 Gene3D G3DSA:3.90.1150.10 282 397 2.0E-16 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 ALX04_RS08035 c3bb2f481b98bad761e9e90617ecc6d5 398 SUPERFAMILY SSF53383 8 394 1.17E-83 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase ALX04_RS08035 c3bb2f481b98bad761e9e90617ecc6d5 398 Pfam PF00155 Aminotransferase class I and II 50 389 4.2E-32 T 28-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 ALX04_RS08035 c3bb2f481b98bad761e9e90617ecc6d5 398 TIGRFAM TIGR04350 C_S_lyase_PatB: putative C-S lyase 12 393 1.4E-120 T 28-03-2018 IPR027619 Putative C-S lyase KEGG: 00270+4.4.1.8|KEGG: 00450+4.4.1.8|MetaCyc: PWY-6936 ALX04_RS11600 2122aa4d1aa116f276f545939307e524 99 SUPERFAMILY SSF54995 5 99 2.88E-31 T 28-03-2018 IPR000529 Ribosomal protein S6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 ALX04_RS11600 2122aa4d1aa116f276f545939307e524 99 Hamap MF_00360 30S ribosomal protein S6 [rpsF]. 4 99 20.22 T 28-03-2018 IPR020814 Ribosomal protein S6, plastid/chloroplast GO:0003735|GO:0005840|GO:0006412|GO:0019843 ALX04_RS11600 2122aa4d1aa116f276f545939307e524 99 TIGRFAM TIGR00166 S6: ribosomal protein bS6 5 98 7.2E-24 T 28-03-2018 IPR000529 Ribosomal protein S6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 ALX04_RS11600 2122aa4d1aa116f276f545939307e524 99 Pfam PF01250 Ribosomal protein S6 6 96 1.0E-24 T 28-03-2018 IPR000529 Ribosomal protein S6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 ALX04_RS11600 2122aa4d1aa116f276f545939307e524 99 Gene3D G3DSA:3.30.70.60 5 99 6.5E-28 T 28-03-2018 IPR014717 Translation elongation factor EF1B/ribosomal protein S6 ALX04_RS10315 ce30406827aa459219085e511eda7b5b 454 TIGRFAM TIGR01499 folC: bifunctional protein FolC 33 445 7.5E-100 T 28-03-2018 IPR001645 Folylpolyglutamate synthetase GO:0004326|GO:0005524|GO:0009396 KEGG: 00790+6.3.2.17|MetaCyc: PWY-2161|Reactome: R-HSA-196757 ALX04_RS10315 ce30406827aa459219085e511eda7b5b 454 Gene3D G3DSA:3.90.190.20 304 447 2.8E-24 T 28-03-2018 ALX04_RS10315 ce30406827aa459219085e511eda7b5b 454 ProSitePatterns PS01011 Folylpolyglutamate synthase signature 1. 49 72 - T 28-03-2018 IPR018109 Folylpolyglutamate synthetase, conserved site GO:0004326|GO:0005524|GO:0009396 Reactome: R-HSA-196757 ALX04_RS10315 ce30406827aa459219085e511eda7b5b 454 Pfam PF02875 Mur ligase family, glutamate ligase domain 303 374 6.8E-11 T 28-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 ALX04_RS10315 ce30406827aa459219085e511eda7b5b 454 SUPERFAMILY SSF53623 9 300 5.38E-70 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 ALX04_RS10315 ce30406827aa459219085e511eda7b5b 454 SUPERFAMILY SSF53244 302 444 1.74E-25 T 28-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 ALX04_RS10315 ce30406827aa459219085e511eda7b5b 454 PIRSF PIRSF001563 5 448 1.1E-109 T 28-03-2018 IPR001645 Folylpolyglutamate synthetase GO:0004326|GO:0005524|GO:0009396 KEGG: 00790+6.3.2.17|MetaCyc: PWY-2161|Reactome: R-HSA-196757 ALX04_RS10315 ce30406827aa459219085e511eda7b5b 454 Gene3D G3DSA:3.40.1190.10 8 303 1.9E-67 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 ALX04_RS10315 ce30406827aa459219085e511eda7b5b 454 Pfam PF08245 Mur ligase middle domain 51 277 5.5E-12 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 ALX04_RS13540 3faeda1cb14b95fd85e21a0c2742212a 296 ProSitePatterns PS01131 Ribosomal RNA adenine dimethylases signature. 55 82 - T 28-03-2018 IPR020596 Ribosomal RNA adenine methylase transferase, conserved site GO:0000154|GO:0000179|GO:0008649 ALX04_RS13540 3faeda1cb14b95fd85e21a0c2742212a 296 Pfam PF00398 Ribosomal RNA adenine dimethylase 24 285 6.1E-64 T 28-03-2018 IPR001737 Ribosomal RNA adenine methyltransferase KsgA/Erm ALX04_RS13540 3faeda1cb14b95fd85e21a0c2742212a 296 Gene3D G3DSA:1.10.8.100 227 292 2.3E-22 T 28-03-2018 IPR023165 rRNA adenine dimethylase-like Reactome: R-HSA-2151201|Reactome: R-HSA-6793080 ALX04_RS13540 3faeda1cb14b95fd85e21a0c2742212a 296 Gene3D G3DSA:3.40.50.150 9 226 1.2E-57 T 28-03-2018 ALX04_RS13540 3faeda1cb14b95fd85e21a0c2742212a 296 TIGRFAM TIGR00755 ksgA: ribosomal RNA small subunit methyltransferase A 24 289 4.6E-82 T 28-03-2018 IPR011530 Ribosomal RNA adenine dimethylase GO:0000179|GO:0006364 ALX04_RS13540 3faeda1cb14b95fd85e21a0c2742212a 296 SUPERFAMILY SSF53335 22 292 3.67E-75 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase ALX04_RS13540 3faeda1cb14b95fd85e21a0c2742212a 296 SMART SM00650 39 215 2.8E-80 T 28-03-2018 IPR020598 Ribosomal RNA adenine methylase transferase, N-terminal GO:0000154|GO:0000179|GO:0008649 ALX04_RS13540 3faeda1cb14b95fd85e21a0c2742212a 296 Hamap MF_00607 Ribosomal RNA small subunit methyltransferase A [rsmA]. 23 291 55.64 T 28-03-2018 IPR011530 Ribosomal RNA adenine dimethylase GO:0000179|GO:0006364 ALX04_RS06235 52268129cc3026b95a44d5979d037e31 153 Gene3D G3DSA:3.30.450.40 5 153 3.0E-21 T 28-03-2018 IPR029016 GAF domain-like ALX04_RS06235 52268129cc3026b95a44d5979d037e31 153 ProSitePatterns PS01320 Uncharacterized protein family UPF0067 signature. 91 108 - T 28-03-2018 IPR000614 Free Met sulfoxide reductase conserved site ALX04_RS06235 52268129cc3026b95a44d5979d037e31 153 SUPERFAMILY SSF55781 11 152 1.83E-38 T 28-03-2018 IPR029016 GAF domain-like ALX04_RS06235 52268129cc3026b95a44d5979d037e31 153 Pfam PF13185 GAF domain 44 152 9.1E-10 T 28-03-2018 IPR003018 GAF domain GO:0005515 ALX04_RS08965 32cacef6b1dd392400c76b3885bd0fd5 323 Gene3D G3DSA:2.130.10.10 23 225 5.0E-4 T 28-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 ALX04_RS08965 32cacef6b1dd392400c76b3885bd0fd5 323 Pfam PF13240 zinc-ribbon domain 3 25 3.2E-9 T 28-03-2018 IPR026870 Zinc-ribbon domain Reactome: R-HSA-202670 ALX04_RS08965 32cacef6b1dd392400c76b3885bd0fd5 323 Gene3D G3DSA:2.20.28.20 3 22 2.7E-5 T 28-03-2018 ALX04_RS11685 6c7522f0fe27df7f98c16a93d8a6a776 223 Gene3D G3DSA:3.40.50.1000 88 223 1.1E-18 T 28-03-2018 IPR023214 HAD-like domain ALX04_RS11685 6c7522f0fe27df7f98c16a93d8a6a776 223 TIGRFAM TIGR01990 bPGM: beta-phosphoglucomutase 7 195 3.6E-75 T 28-03-2018 IPR010972 Beta-phosphoglucomutase GO:0000287|GO:0005975|GO:0008801 KEGG: 00500+5.4.2.6|MetaCyc: PWY-2721|MetaCyc: PWY-2722|MetaCyc: PWY-7459 ALX04_RS11685 6c7522f0fe27df7f98c16a93d8a6a776 223 SUPERFAMILY SSF56784 7 213 3.54E-42 T 28-03-2018 IPR023214 HAD-like domain ALX04_RS11685 6c7522f0fe27df7f98c16a93d8a6a776 223 Pfam PF13419 Haloacid dehalogenase-like hydrolase 11 193 9.9E-21 T 28-03-2018 IPR023214 HAD-like domain ALX04_RS11685 6c7522f0fe27df7f98c16a93d8a6a776 223 Gene3D G3DSA:3.40.50.1000 2 37 0.027 T 28-03-2018 IPR023214 HAD-like domain ALX04_RS11685 6c7522f0fe27df7f98c16a93d8a6a776 223 Gene3D G3DSA:1.10.150.240 38 87 5.6E-18 T 28-03-2018 IPR023198 Phosphoglycolate phosphatase, domain 2 ALX04_RS11685 6c7522f0fe27df7f98c16a93d8a6a776 223 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 87 193 1.6E-15 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 ALX04_RS11685 6c7522f0fe27df7f98c16a93d8a6a776 223 TIGRFAM TIGR02009 PGMB-YQAB-SF: beta-phosphoglucomutase family hydrolase 7 194 3.6E-54 T 28-03-2018 IPR010976 Beta-phosphoglucomutase hydrolase ALX04_RS14865 0a7558e4b2ea6afe9fa409e36aad500d 302 TIGRFAM TIGR00179 murB: UDP-N-acetylenolpyruvoylglucosamine reductase 20 296 2.3E-72 T 28-03-2018 IPR003170 UDP-N-acetylenolpyruvoylglucosamine reductase GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387 ALX04_RS14865 0a7558e4b2ea6afe9fa409e36aad500d 302 Gene3D G3DSA:3.90.78.10 215 299 1.4E-26 T 28-03-2018 IPR011601 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387 ALX04_RS14865 0a7558e4b2ea6afe9fa409e36aad500d 302 SUPERFAMILY SSF56194 193 297 9.94E-39 T 28-03-2018 IPR011601 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387 ALX04_RS14865 0a7558e4b2ea6afe9fa409e36aad500d 302 Gene3D G3DSA:3.30.465.10 84 214 6.2E-39 T 28-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 ALX04_RS14865 0a7558e4b2ea6afe9fa409e36aad500d 302 SUPERFAMILY SSF56176 3 191 2.24E-45 T 28-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 ALX04_RS14865 0a7558e4b2ea6afe9fa409e36aad500d 302 Hamap MF_00037 UDP-N-acetylenolpyruvoylglucosamine reductase [murB]. 1 302 93.415 T 28-03-2018 IPR003170 UDP-N-acetylenolpyruvoylglucosamine reductase GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387 ALX04_RS14865 0a7558e4b2ea6afe9fa409e36aad500d 302 Pfam PF02873 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain 197 295 4.5E-29 T 28-03-2018 IPR011601 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387 ALX04_RS14865 0a7558e4b2ea6afe9fa409e36aad500d 302 Gene3D G3DSA:3.30.43.10 8 83 5.2E-21 T 28-03-2018 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 ALX04_RS14865 0a7558e4b2ea6afe9fa409e36aad500d 302 Pfam PF01565 FAD binding domain 33 161 6.7E-23 T 28-03-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 ALX04_RS11545 8968f9fe67253b1b3fdab77bf7bdce0b 463 Gene3D G3DSA:1.20.120.430 290 463 9.3E-35 T 28-03-2018 ALX04_RS11545 8968f9fe67253b1b3fdab77bf7bdce0b 463 Pfam PF10396 GTP-binding protein TrmE N-terminus 9 127 1.3E-41 T 28-03-2018 IPR018948 GTP-binding protein TrmE, N-terminal Reactome: R-HSA-6787450 ALX04_RS11545 8968f9fe67253b1b3fdab77bf7bdce0b 463 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 228 371 3.0E-26 T 28-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 ALX04_RS11545 8968f9fe67253b1b3fdab77bf7bdce0b 463 TIGRFAM TIGR00450 mnmE_trmE_thdF: tRNA modification GTPase TrmE 15 463 1.4E-136 T 28-03-2018 IPR004520 tRNA modification GTPase MnmE GO:0003924|GO:0005525|GO:0005622|GO:0006400 Reactome: R-HSA-6787450 ALX04_RS11545 8968f9fe67253b1b3fdab77bf7bdce0b 463 Gene3D G3DSA:1.20.120.430 129 289 1.3E-28 T 28-03-2018 ALX04_RS11545 8968f9fe67253b1b3fdab77bf7bdce0b 463 Hamap MF_00379 tRNA modification GTPase MnmE [mnmE]. 8 463 34.541 T 28-03-2018 IPR004520 tRNA modification GTPase MnmE GO:0003924|GO:0005525|GO:0005622|GO:0006400 Reactome: R-HSA-6787450 ALX04_RS11545 8968f9fe67253b1b3fdab77bf7bdce0b 463 Pfam PF01926 50S ribosome-binding GTPase 228 339 1.6E-25 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 ALX04_RS11545 8968f9fe67253b1b3fdab77bf7bdce0b 463 Pfam PF12631 MnmE helical domain 130 460 4.4E-61 T 28-03-2018 IPR025867 MnmE, helical domain Reactome: R-HSA-6787450 ALX04_RS11545 8968f9fe67253b1b3fdab77bf7bdce0b 463 Gene3D G3DSA:3.30.1360.120 2 128 2.4E-46 T 28-03-2018 ALX04_RS11545 8968f9fe67253b1b3fdab77bf7bdce0b 463 SUPERFAMILY SSF52540 81 170 1.75E-42 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase ALX04_RS11545 8968f9fe67253b1b3fdab77bf7bdce0b 463 SUPERFAMILY SSF52540 205 379 1.75E-42 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase ALX04_RS11545 8968f9fe67253b1b3fdab77bf7bdce0b 463 SUPERFAMILY SSF116878 128 228 2.22E-51 T 28-03-2018 ALX04_RS11545 8968f9fe67253b1b3fdab77bf7bdce0b 463 SUPERFAMILY SSF116878 388 463 2.22E-51 T 28-03-2018 ALX04_RS00470 43f88691ad14fe5be7c478b68e8f9706 60 Hamap MF_01371_B 50S ribosomal protein L30 [rpmD]. 1 58 15.051 T 28-03-2018 IPR005996 Ribosomal protein L30, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 ALX04_RS00470 43f88691ad14fe5be7c478b68e8f9706 60 Pfam PF00327 Ribosomal protein L30p/L7e 4 54 3.4E-16 T 28-03-2018 IPR016082 Ribosomal protein L30, ferredoxin-like fold domain ALX04_RS00470 43f88691ad14fe5be7c478b68e8f9706 60 PIRSF PIRSF002211 1 60 2.0E-21 T 28-03-2018 IPR005996 Ribosomal protein L30, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 ALX04_RS00470 43f88691ad14fe5be7c478b68e8f9706 60 SUPERFAMILY SSF55129 1 58 1.44E-16 T 28-03-2018 IPR016082 Ribosomal protein L30, ferredoxin-like fold domain ALX04_RS00470 43f88691ad14fe5be7c478b68e8f9706 60 TIGRFAM TIGR01308 rpmD_bact: ribosomal protein uL30 4 57 4.7E-18 T 28-03-2018 IPR005996 Ribosomal protein L30, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 ALX04_RS00470 43f88691ad14fe5be7c478b68e8f9706 60 Gene3D G3DSA:3.30.1390.20 4 57 5.3E-19 T 28-03-2018 IPR016082 Ribosomal protein L30, ferredoxin-like fold domain ALX04_RS07310 219d9b87cc3a9a40362d55c7bfc96df7 218 TIGRFAM TIGR00070 hisG: ATP phosphoribosyltransferase 6 186 6.4E-59 T 28-03-2018 IPR013820 ATP phosphoribosyltransferase, catalytic domain GO:0000105|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17 ALX04_RS07310 219d9b87cc3a9a40362d55c7bfc96df7 218 SUPERFAMILY SSF53850 3 209 1.3E-60 T 28-03-2018 ALX04_RS07310 219d9b87cc3a9a40362d55c7bfc96df7 218 Pfam PF01634 ATP phosphoribosyltransferase 57 205 2.5E-44 T 28-03-2018 IPR013820 ATP phosphoribosyltransferase, catalytic domain GO:0000105|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17 ALX04_RS07310 219d9b87cc3a9a40362d55c7bfc96df7 218 Gene3D G3DSA:3.40.190.10 1 113 1.6E-33 T 28-03-2018 ALX04_RS07310 219d9b87cc3a9a40362d55c7bfc96df7 218 Hamap MF_01018 ATP phosphoribosyltransferase [hisG]. 5 210 56.547 T 28-03-2018 IPR024893 ATP phosphoribosyltransferase HisG, short form GO:0000105|GO:0003879 KEGG: 00340+2.4.2.17 ALX04_RS07310 219d9b87cc3a9a40362d55c7bfc96df7 218 Gene3D G3DSA:3.40.190.10 114 177 7.7E-24 T 28-03-2018 ALX04_RS07310 219d9b87cc3a9a40362d55c7bfc96df7 218 ProSitePatterns PS01316 ATP phosphoribosyltransferase signature. 145 166 - T 28-03-2018 IPR018198 ATP phosphoribosyltransferase, conserved site GO:0003879 KEGG: 00340+2.4.2.17 ALX04_RS06200 e23cbe17a28863cde92d6d80593ce754 889 TIGRFAM TIGR00422 valS: valine--tRNA ligase 9 868 0.0 T 28-03-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 ALX04_RS06200 e23cbe17a28863cde92d6d80593ce754 889 SUPERFAMILY SSF47323 583 835 1.87E-72 T 28-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 ALX04_RS06200 e23cbe17a28863cde92d6d80593ce754 889 PRINTS PR00986 Valyl-tRNA synthetase signature 452 473 8.3E-34 T 28-03-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 ALX04_RS06200 e23cbe17a28863cde92d6d80593ce754 889 PRINTS PR00986 Valyl-tRNA synthetase signature 43 54 8.3E-34 T 28-03-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 ALX04_RS06200 e23cbe17a28863cde92d6d80593ce754 889 PRINTS PR00986 Valyl-tRNA synthetase signature 484 502 8.3E-34 T 28-03-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 ALX04_RS06200 e23cbe17a28863cde92d6d80593ce754 889 PRINTS PR00986 Valyl-tRNA synthetase signature 243 260 8.3E-34 T 28-03-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 ALX04_RS06200 e23cbe17a28863cde92d6d80593ce754 889 PRINTS PR00986 Valyl-tRNA synthetase signature 358 371 8.3E-34 T 28-03-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 ALX04_RS06200 e23cbe17a28863cde92d6d80593ce754 889 Gene3D G3DSA:1.10.730.10 530 754 9.9E-78 T 28-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 ALX04_RS06200 e23cbe17a28863cde92d6d80593ce754 889 Pfam PF08264 Anticodon-binding domain of tRNA 615 761 4.3E-45 T 28-03-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0000166|GO:0006418 ALX04_RS06200 e23cbe17a28863cde92d6d80593ce754 889 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 50 61 - T 28-03-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 ALX04_RS06200 e23cbe17a28863cde92d6d80593ce754 889 Gene3D G3DSA:1.10.287.380 814 883 5.8E-23 T 28-03-2018 IPR019499 Valyl-tRNA synthetase, tRNA-binding arm GO:0000166|GO:0004832|GO:0005524|GO:0005737|GO:0006438 KEGG: 00970+6.1.1.9|Reactome: R-HSA-379716 ALX04_RS06200 e23cbe17a28863cde92d6d80593ce754 889 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 22 572 2.4E-219 T 28-03-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 ALX04_RS06200 e23cbe17a28863cde92d6d80593ce754 889 Gene3D G3DSA:3.90.740.10 215 246 3.4E-6 T 28-03-2018 ALX04_RS06200 e23cbe17a28863cde92d6d80593ce754 889 Gene3D G3DSA:3.90.740.10 247 438 4.0E-63 T 28-03-2018 ALX04_RS06200 e23cbe17a28863cde92d6d80593ce754 889 SUPERFAMILY SSF52374 353 582 1.36E-139 T 28-03-2018 ALX04_RS06200 e23cbe17a28863cde92d6d80593ce754 889 SUPERFAMILY SSF52374 7 199 1.36E-139 T 28-03-2018 ALX04_RS06200 e23cbe17a28863cde92d6d80593ce754 889 SUPERFAMILY SSF46589 821 885 7.85E-16 T 28-03-2018 IPR010978 tRNA-binding arm GO:0000166 ALX04_RS06200 e23cbe17a28863cde92d6d80593ce754 889 Pfam PF10458 Valyl tRNA synthetase tRNA binding arm 821 885 5.4E-18 T 28-03-2018 IPR019499 Valyl-tRNA synthetase, tRNA-binding arm GO:0000166|GO:0004832|GO:0005524|GO:0005737|GO:0006438 KEGG: 00970+6.1.1.9|Reactome: R-HSA-379716 ALX04_RS06200 e23cbe17a28863cde92d6d80593ce754 889 Gene3D G3DSA:3.40.50.620 23 214 6.1E-29 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold ALX04_RS06200 e23cbe17a28863cde92d6d80593ce754 889 Gene3D G3DSA:3.40.50.620 439 529 1.9E-30 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold ALX04_RS06200 e23cbe17a28863cde92d6d80593ce754 889 Hamap MF_02004 Valine--tRNA ligase [valS]. 9 886 15.819 T 28-03-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 ALX04_RS06200 e23cbe17a28863cde92d6d80593ce754 889 SUPERFAMILY SSF50677 198 354 4.84E-60 T 28-03-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 ALX04_RS04710 f424863495088cb07a0ed7d515f62e39 389 Gene3D G3DSA:3.40.47.10 175 320 9.7E-37 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 ALX04_RS04710 f424863495088cb07a0ed7d515f62e39 389 SUPERFAMILY SSF53901 2 166 2.07E-39 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 ALX04_RS04710 f424863495088cb07a0ed7d515f62e39 389 Pfam PF01154 Hydroxymethylglutaryl-coenzyme A synthase N terminal 2 165 4.1E-18 T 28-03-2018 IPR013528 Hydroxymethylglutaryl-coenzyme A synthase, N-terminal GO:0004421|GO:0008299 Reactome: R-HSA-1989781 ALX04_RS04710 f424863495088cb07a0ed7d515f62e39 389 Pfam PF08540 Hydroxymethylglutaryl-coenzyme A synthase C terminal 261 351 4.2E-11 T 28-03-2018 IPR013746 Hydroxymethylglutaryl-coenzyme A synthase C-terminal domain GO:0004421|GO:0008299 KEGG: 00072+2.3.3.10|KEGG: 00280+2.3.3.10|KEGG: 00650+2.3.3.10|KEGG: 00900+2.3.3.10|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-7571|MetaCyc: PWY-922|Reactome: R-HSA-1989781 ALX04_RS04710 f424863495088cb07a0ed7d515f62e39 389 SUPERFAMILY SSF53901 173 385 1.87E-57 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 ALX04_RS04710 f424863495088cb07a0ed7d515f62e39 389 Gene3D G3DSA:3.40.47.10 6 170 3.8E-11 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 ALX04_RS04710 f424863495088cb07a0ed7d515f62e39 389 TIGRFAM TIGR01835 HMG-CoA-S_prok: hydroxymethylglutaryl-CoA synthase 3 384 2.0E-134 T 28-03-2018 IPR011554 Hydroxymethylglutaryl-CoA synthase, prokaryotic KEGG: 00072+2.3.3.10|KEGG: 00280+2.3.3.10|KEGG: 00650+2.3.3.10|KEGG: 00900+2.3.3.10|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-7571|MetaCyc: PWY-922 ALX04_RS03735 00ebfec4f07e7541284f5a335a83d6ff 144 Hamap MF_01400 Peptide methionine sulfoxide reductase MsrB [msrB]. 1 128 37.337 T 28-03-2018 IPR002579 Peptide methionine sulphoxide reductase MrsB GO:0033743|GO:0055114 Reactome: R-HSA-5676934 ALX04_RS03735 00ebfec4f07e7541284f5a335a83d6ff 144 TIGRFAM TIGR00357 TIGR00357: methionine-R-sulfoxide reductase 3 136 1.6E-60 T 28-03-2018 IPR002579 Peptide methionine sulphoxide reductase MrsB GO:0033743|GO:0055114 Reactome: R-HSA-5676934 ALX04_RS03735 00ebfec4f07e7541284f5a335a83d6ff 144 SUPERFAMILY SSF51316 2 142 9.94E-60 T 28-03-2018 IPR011057 Mss4-like ALX04_RS03735 00ebfec4f07e7541284f5a335a83d6ff 144 Pfam PF01641 SelR domain 7 127 8.1E-51 T 28-03-2018 IPR002579 Peptide methionine sulphoxide reductase MrsB GO:0033743|GO:0055114 Reactome: R-HSA-5676934 ALX04_RS03735 00ebfec4f07e7541284f5a335a83d6ff 144 Gene3D G3DSA:2.170.150.20 1 144 7.8E-57 T 28-03-2018 ALX04_RS05275 52a0e6f7fb42cfd75dff2d27381840a3 187 Pfam PF03602 Conserved hypothetical protein 95 1 181 1.7E-58 T 28-03-2018 ALX04_RS05275 52a0e6f7fb42cfd75dff2d27381840a3 187 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 117 123 - T 28-03-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 ALX04_RS05275 52a0e6f7fb42cfd75dff2d27381840a3 187 PIRSF PIRSF004553 1 184 2.5E-48 T 28-03-2018 IPR004398 RNA methyltransferase, RsmD GO:0008168|GO:0031167 ALX04_RS05275 52a0e6f7fb42cfd75dff2d27381840a3 187 TIGRFAM TIGR00095 TIGR00095: 16S rRNA (guanine(966)-N(2))-methyltransferase RsmD 2 182 2.9E-52 T 28-03-2018 IPR004398 RNA methyltransferase, RsmD GO:0008168|GO:0031167 ALX04_RS05275 52a0e6f7fb42cfd75dff2d27381840a3 187 SUPERFAMILY SSF53335 1 181 2.39E-53 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase ALX04_RS05275 52a0e6f7fb42cfd75dff2d27381840a3 187 Gene3D G3DSA:3.40.50.150 1 184 3.8E-34 T 28-03-2018 ALX04_RS11135 3046d6c397261ad69d74923ff182d32e 445 PIRSF PIRSF006351 3 439 2.1E-149 T 28-03-2018 IPR004796 Phosphotransferase system, cellobiose-type IIC component GO:0008982|GO:0009401|GO:0016021 ALX04_RS11135 3046d6c397261ad69d74923ff182d32e 445 Pfam PF02378 Phosphotransferase system, EIIC 28 354 6.8E-55 T 28-03-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 ALX04_RS11135 3046d6c397261ad69d74923ff182d32e 445 TIGRFAM TIGR00410 lacE: PTS system, lactose/cellobiose family IIC component 14 429 2.0E-106 T 28-03-2018 IPR004501 Phosphotransferase system, EIIC component, type 3 GO:0008982|GO:0009401|GO:0016021 ALX04_RS11900 efd8757dd32a8b2032000eeb09e3d270 163 Gene3D G3DSA:3.40.630.30 3 159 2.9E-27 T 28-03-2018 ALX04_RS11900 efd8757dd32a8b2032000eeb09e3d270 163 Pfam PF13673 Acetyltransferase (GNAT) domain 37 147 4.2E-15 T 28-03-2018 IPR000182 GNAT domain GO:0008080 ALX04_RS11900 efd8757dd32a8b2032000eeb09e3d270 163 SUPERFAMILY SSF55729 8 149 2.9E-26 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase ALX04_RS15315 1e64b94fae3f25562222cd3e6250dce2 127 Gene3D G3DSA:2.20.110.10 35 127 3.5E-11 T 28-03-2018 ALX04_RS15315 1e64b94fae3f25562222cd3e6250dce2 127 Pfam PF02493 MORN repeat 68 90 0.0013 T 28-03-2018 IPR003409 MORN motif ALX04_RS15315 1e64b94fae3f25562222cd3e6250dce2 127 SUPERFAMILY SSF82185 43 117 5.49E-13 T 28-03-2018 ALX04_RS15315 1e64b94fae3f25562222cd3e6250dce2 127 PIRSF PIRSF034300 1 127 9.3E-56 T 28-03-2018 IPR014590 Uncharacterised conserved protein MORN repeat-containing ALX04_RS15375 d998da27dc8574aad12bae5574df74ff 957 Pfam PF04851 Type III restriction enzyme, res subunit 254 423 8.6E-30 T 28-03-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 ALX04_RS15375 d998da27dc8574aad12bae5574df74ff 957 TIGRFAM TIGR00348 hsdR: type I site-specific deoxyribonuclease, HsdR family 10 689 5.3E-140 T 28-03-2018 IPR004473 Restriction endonuclease, type I, HsdR GO:0003677|GO:0005524|GO:0009035|GO:0009307 ALX04_RS15375 d998da27dc8574aad12bae5574df74ff 957 Pfam PF12008 Type I restriction and modification enzyme - subunit R C terminal 694 950 4.5E-48 T 28-03-2018 IPR022625 Type-1 restriction enzyme R protein, C-terminal ALX04_RS15375 d998da27dc8574aad12bae5574df74ff 957 SMART SM00487 250 446 2.3E-12 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain ALX04_RS15375 d998da27dc8574aad12bae5574df74ff 957 Gene3D G3DSA:3.40.50.300 229 430 3.1E-19 T 28-03-2018 ALX04_RS15375 d998da27dc8574aad12bae5574df74ff 957 Pfam PF04313 Type I restriction enzyme R protein N terminus (HSDR_N) 7 198 4.8E-30 T 28-03-2018 IPR007409 Restriction endonuclease, type I, HsdR, N-terminal GO:0003677|GO:0004519|GO:0006304 ALX04_RS15375 d998da27dc8574aad12bae5574df74ff 957 Gene3D G3DSA:3.40.50.300 482 686 0.0015 T 28-03-2018 ALX04_RS15375 d998da27dc8574aad12bae5574df74ff 957 SUPERFAMILY SSF52540 216 425 1.01E-26 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase ALX04_RS03445 a9bb9bb988918287f3d13141308bf1fc 359 SUPERFAMILY SSF52317 1 177 8.24E-36 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like ALX04_RS03445 a9bb9bb988918287f3d13141308bf1fc 359 Gene3D G3DSA:3.50.30.60 175 359 1.1E-49 T 28-03-2018 IPR027461 LD-carboxypeptidase A, C-terminal domain ALX04_RS03445 a9bb9bb988918287f3d13141308bf1fc 359 Pfam PF02016 LD-carboxypeptidase 13 341 2.9E-62 T 28-03-2018 IPR003507 Peptidase family S66 ALX04_RS03445 a9bb9bb988918287f3d13141308bf1fc 359 SUPERFAMILY SSF141986 202 348 2.75E-24 T 28-03-2018 IPR027461 LD-carboxypeptidase A, C-terminal domain ALX04_RS03445 a9bb9bb988918287f3d13141308bf1fc 359 Gene3D G3DSA:3.40.50.10740 1 174 7.5E-41 T 28-03-2018 IPR027478 Murein tetrapeptide carboxypeptidase, N-terminal domain ALX04_RS03445 a9bb9bb988918287f3d13141308bf1fc 359 PIRSF PIRSF028757 1 357 6.6E-54 T 28-03-2018 IPR003507 Peptidase family S66 ALX04_RS11690 aa7d737c1846c48ffae571c365ff4431 906 Pfam PF03633 Glycosyl hydrolase family 65, C-terminal domain 846 894 6.2E-7 T 28-03-2018 IPR005194 Glycoside hydrolase family 65, C-terminal ALX04_RS11690 aa7d737c1846c48ffae571c365ff4431 906 Gene3D G3DSA:2.60.420.10 829 897 1.3E-11 T 28-03-2018 ALX04_RS11690 aa7d737c1846c48ffae571c365ff4431 906 SUPERFAMILY SSF74650 117 377 2.1E-61 T 28-03-2018 IPR011013 Galactose mutarotase-like domain GO:0003824|GO:0005975|GO:0030246 ALX04_RS11690 aa7d737c1846c48ffae571c365ff4431 906 Gene3D G3DSA:1.50.10.10 421 828 9.7E-85 T 28-03-2018 ALX04_RS11690 aa7d737c1846c48ffae571c365ff4431 906 Pfam PF03636 Glycosyl hydrolase family 65, N-terminal domain 126 374 9.1E-52 T 28-03-2018 IPR005196 Glycoside hydrolase, family 65, N-terminal GO:0003824|GO:0005975 ALX04_RS11690 aa7d737c1846c48ffae571c365ff4431 906 Pfam PF03632 Glycosyl hydrolase family 65 central catalytic domain 427 836 3.2E-120 T 28-03-2018 IPR005195 Glycoside hydrolase, family 65, central catalytic GO:0003824|GO:0005975 ALX04_RS11690 aa7d737c1846c48ffae571c365ff4431 906 Gene3D G3DSA:2.70.98.40 109 378 1.2E-61 T 28-03-2018 IPR005196 Glycoside hydrolase, family 65, N-terminal GO:0003824|GO:0005975 ALX04_RS11690 aa7d737c1846c48ffae571c365ff4431 906 SUPERFAMILY SSF48208 381 885 1.24E-94 T 28-03-2018 IPR008928 Six-hairpin glycosidase-like GO:0003824 ALX04_RS08665 d147bf6d4d6b15b16ee6b8f776ec48f8 285 ProSitePatterns PS00798 Aldo/keto reductase family signature 1. 39 56 - T 28-03-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 ALX04_RS08665 d147bf6d4d6b15b16ee6b8f776ec48f8 285 PRINTS PR00069 Aldo-keto reductase signature 35 59 4.1E-44 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 ALX04_RS08665 d147bf6d4d6b15b16ee6b8f776ec48f8 285 PRINTS PR00069 Aldo-keto reductase signature 154 183 4.1E-44 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 ALX04_RS08665 d147bf6d4d6b15b16ee6b8f776ec48f8 285 PRINTS PR00069 Aldo-keto reductase signature 91 109 4.1E-44 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 ALX04_RS08665 d147bf6d4d6b15b16ee6b8f776ec48f8 285 PRINTS PR00069 Aldo-keto reductase signature 193 217 4.1E-44 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 ALX04_RS08665 d147bf6d4d6b15b16ee6b8f776ec48f8 285 PRINTS PR00069 Aldo-keto reductase signature 120 137 4.1E-44 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 ALX04_RS08665 d147bf6d4d6b15b16ee6b8f776ec48f8 285 Pfam PF00248 Aldo/keto reductase family 16 258 9.6E-50 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain ALX04_RS08665 d147bf6d4d6b15b16ee6b8f776ec48f8 285 Gene3D G3DSA:3.20.20.100 1 274 3.1E-93 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain ALX04_RS08665 d147bf6d4d6b15b16ee6b8f776ec48f8 285 SUPERFAMILY SSF51430 2 266 1.96E-89 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain ALX04_RS08665 d147bf6d4d6b15b16ee6b8f776ec48f8 285 ProSitePatterns PS00062 Aldo/keto reductase family signature 2. 120 137 - T 28-03-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 ALX04_RS08665 d147bf6d4d6b15b16ee6b8f776ec48f8 285 PIRSF PIRSF000097 110 272 1.9E-46 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 ALX04_RS08665 d147bf6d4d6b15b16ee6b8f776ec48f8 285 PIRSF PIRSF000097 1 115 9.5E-40 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 ALX04_RS08665 d147bf6d4d6b15b16ee6b8f776ec48f8 285 ProSitePatterns PS00063 Aldo/keto reductase family putative active site signature. 226 241 - T 28-03-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 ALX04_RS06620 b99b01c4b56df8b476f8aec4c4e6a179 269 Pfam PF05709 Phage tail protein 45 269 6.5E-26 T 28-03-2018 IPR008841 Siphovirus-type tail component ALX04_RS12170 5d427592bd5f60cfc176c2ff81d0fd57 151 Gene3D G3DSA:3.40.50.450 7 150 1.1E-24 T 28-03-2018 ALX04_RS12170 5d427592bd5f60cfc176c2ff81d0fd57 151 Pfam PF05014 Nucleoside 2-deoxyribosyltransferase 12 109 5.6E-16 T 28-03-2018 IPR007710 Nucleoside 2-deoxyribosyltransferase GO:0009159|GO:0050144|GO:0070694 Reactome: R-HSA-74259 ALX04_RS12170 5d427592bd5f60cfc176c2ff81d0fd57 151 SUPERFAMILY SSF52309 4 137 1.25E-33 T 28-03-2018 ALX04_RS04905 754e16a6c511a8a9a0dea344a9a956da 115 Pfam PF09643 YopX protein 33 112 2.7E-16 T 28-03-2018 IPR019096 YopX protein ALX04_RS04905 754e16a6c511a8a9a0dea344a9a956da 115 TIGRFAM TIGR01671 phage_TIGR01671: phage conserved hypothetical protein TIGR01671 29 113 4.2E-12 T 28-03-2018 IPR010024 Conserved hypothetical protein CHP1671 ALX04_RS04905 754e16a6c511a8a9a0dea344a9a956da 115 Gene3D G3DSA:2.30.30.290 40 115 4.3E-17 T 28-03-2018 IPR023385 YopX-like domain, beta barrel type ALX04_RS04905 754e16a6c511a8a9a0dea344a9a956da 115 SUPERFAMILY SSF159006 1 112 3.4E-26 T 28-03-2018 ALX04_RS10480 dd73a7ea10d5203e944284bddbb2b475 460 ProSitePatterns PS00218 Amino acid permeases signature. 42 72 - T 28-03-2018 IPR004840 Amino acid permease, conserved site GO:0006865|GO:0016021|GO:0055085 ALX04_RS10480 dd73a7ea10d5203e944284bddbb2b475 460 Pfam PF00324 Amino acid permease 17 434 2.9E-89 T 28-03-2018 IPR004841 Amino acid permease/ SLC12A domain GO:0006810|GO:0016020|GO:0055085 ALX04_RS10480 dd73a7ea10d5203e944284bddbb2b475 460 PIRSF PIRSF006060 2 458 1.0E-60 T 28-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 ALX04_RS09655 aca1977f3a4fa78c3a354505c12c9bdc 266 Gene3D G3DSA:2.20.28.20 3 21 6.1E-4 T 28-03-2018 ALX04_RS09655 aca1977f3a4fa78c3a354505c12c9bdc 266 Gene3D G3DSA:2.60.40.10 104 264 0.012 T 28-03-2018 IPR013783 Immunoglobulin-like fold ALX04_RS09655 aca1977f3a4fa78c3a354505c12c9bdc 266 Gene3D G3DSA:2.20.70.10 22 40 0.03 T 28-03-2018 ALX04_RS09655 aca1977f3a4fa78c3a354505c12c9bdc 266 Pfam PF13240 zinc-ribbon domain 4 24 9.9E-8 T 28-03-2018 IPR026870 Zinc-ribbon domain Reactome: R-HSA-202670 ALX04_RS07080 791a7af8577341572c0ca6b1633a775e 285 Pfam PF06800 Sugar transport protein 4 283 4.3E-108 T 28-03-2018 IPR010651 Sugar transport protein GO:0015144|GO:0016021|GO:0034219 ALX04_RS07080 791a7af8577341572c0ca6b1633a775e 285 SUPERFAMILY SSF103481 185 282 2.48E-7 T 28-03-2018 ALX04_RS07080 791a7af8577341572c0ca6b1633a775e 285 SUPERFAMILY SSF103481 36 131 3.66E-9 T 28-03-2018 ALX04_RS05930 8aa817808560fe83d3db629203620e83 153 Pfam PF13411 MerR HTH family regulatory protein 2 68 1.5E-19 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 ALX04_RS05930 8aa817808560fe83d3db629203620e83 153 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 14 27 6.8E-8 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 ALX04_RS05930 8aa817808560fe83d3db629203620e83 153 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 3 14 6.8E-8 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 ALX04_RS05930 8aa817808560fe83d3db629203620e83 153 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 38 58 6.8E-8 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 ALX04_RS05930 8aa817808560fe83d3db629203620e83 153 SMART SM00422 2 71 1.1E-21 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 ALX04_RS05930 8aa817808560fe83d3db629203620e83 153 Gene3D G3DSA:1.10.1660.10 57 145 3.9E-18 T 28-03-2018 ALX04_RS05930 8aa817808560fe83d3db629203620e83 153 Gene3D G3DSA:1.10.1660.10 1 56 5.1E-22 T 28-03-2018 ALX04_RS05930 8aa817808560fe83d3db629203620e83 153 SUPERFAMILY SSF46955 2 115 2.93E-32 T 28-03-2018 IPR009061 Putative DNA-binding domain ALX04_RS08525 11c77a7364a3b3690ce72ccad4233928 206 SUPERFAMILY SSF51161 2 190 3.74E-52 T 28-03-2018 IPR011004 Trimeric LpxA-like ALX04_RS08525 11c77a7364a3b3690ce72ccad4233928 206 SMART SM01266 5 59 1.7E-22 T 28-03-2018 IPR024688 Maltose/galactoside acetyltransferase GO:0016407 ALX04_RS08525 11c77a7364a3b3690ce72ccad4233928 206 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 131 165 9.8E-9 T 28-03-2018 IPR001451 Hexapeptide repeat ALX04_RS08525 11c77a7364a3b3690ce72ccad4233928 206 Gene3D G3DSA:2.160.10.10 2 199 2.4E-51 T 28-03-2018 ALX04_RS08525 11c77a7364a3b3690ce72ccad4233928 206 Pfam PF12464 Maltose acetyltransferase 7 58 8.2E-16 T 28-03-2018 IPR024688 Maltose/galactoside acetyltransferase GO:0016407 ALX04_RS03625 df3f8b3bb99dadf06d81c919c5abca54 102 Gene3D G3DSA:3.10.450.150 2 99 6.5E-25 T 28-03-2018 ALX04_RS03625 df3f8b3bb99dadf06d81c919c5abca54 102 Pfam PF06124 Staphylococcal protein of unknown function (DUF960) 7 99 2.5E-26 T 28-03-2018 IPR009303 Protein of unknown function DUF960 ALX04_RS14620 8dfce68f199b1037b4f57d2ff6e5022c 226 SUPERFAMILY SSF141868 4 218 2.09E-30 T 28-03-2018 IPR001633 EAL domain ALX04_RS14620 8dfce68f199b1037b4f57d2ff6e5022c 226 Pfam PF00563 EAL domain 5 217 3.2E-19 T 28-03-2018 IPR001633 EAL domain ALX04_RS14620 8dfce68f199b1037b4f57d2ff6e5022c 226 Gene3D G3DSA:3.20.20.450 2 222 1.9E-24 T 28-03-2018 IPR001633 EAL domain ALX04_RS14620 8dfce68f199b1037b4f57d2ff6e5022c 226 SMART SM00052 3 222 9.5E-6 T 28-03-2018 IPR001633 EAL domain ALX04_RS03845 1b78f6b508fb375712319e2410a4d45d 73 Hamap MF_01538 UPF0346 protein . 1 71 25.475 T 28-03-2018 IPR010673 Protein of unknown function UPF0346 ALX04_RS03845 1b78f6b508fb375712319e2410a4d45d 73 Gene3D G3DSA:1.10.150.260 3 71 3.7E-28 T 28-03-2018 IPR023089 YozE SAM-like domain ALX04_RS03845 1b78f6b508fb375712319e2410a4d45d 73 Pfam PF06855 YozE SAM-like fold 4 69 6.9E-30 T 28-03-2018 IPR023089 YozE SAM-like domain ALX04_RS03845 1b78f6b508fb375712319e2410a4d45d 73 PIRSF PIRSF037262 1 73 2.2E-36 T 28-03-2018 IPR010673 Protein of unknown function UPF0346 ALX04_RS03845 1b78f6b508fb375712319e2410a4d45d 73 SUPERFAMILY SSF140652 3 71 1.96E-31 T 28-03-2018 IPR023089 YozE SAM-like domain ALX04_RS09085 3422e2cd5721a4410253117531412658 260 Pfam PF13731 WxL domain surface cell wall-binding 30 256 8.8E-46 T 28-03-2018 IPR027994 WxL domain ALX04_RS01605 ed86c7cae2ba650cfd3f4ef796d9883b 500 Pfam PF07690 Major Facilitator Superfamily 16 404 2.3E-58 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 ALX04_RS01605 ed86c7cae2ba650cfd3f4ef796d9883b 500 Gene3D G3DSA:1.20.1250.20 7 198 8.9E-38 T 28-03-2018 ALX04_RS01605 ed86c7cae2ba650cfd3f4ef796d9883b 500 SUPERFAMILY SSF103473 245 415 1.15E-69 T 28-03-2018 IPR020846 Major facilitator superfamily domain ALX04_RS01605 ed86c7cae2ba650cfd3f4ef796d9883b 500 SUPERFAMILY SSF103473 458 479 1.15E-69 T 28-03-2018 IPR020846 Major facilitator superfamily domain ALX04_RS01605 ed86c7cae2ba650cfd3f4ef796d9883b 500 SUPERFAMILY SSF103473 11 199 1.15E-69 T 28-03-2018 IPR020846 Major facilitator superfamily domain ALX04_RS01605 ed86c7cae2ba650cfd3f4ef796d9883b 500 PRINTS PR01036 Tetracycline resistance protein TetB signature 14 38 6.2E-10 T 28-03-2018 ALX04_RS01605 ed86c7cae2ba650cfd3f4ef796d9883b 500 PRINTS PR01036 Tetracycline resistance protein TetB signature 352 372 6.2E-10 T 28-03-2018 ALX04_RS01605 ed86c7cae2ba650cfd3f4ef796d9883b 500 PRINTS PR01036 Tetracycline resistance protein TetB signature 298 322 6.2E-10 T 28-03-2018 ALX04_RS01605 ed86c7cae2ba650cfd3f4ef796d9883b 500 PRINTS PR01036 Tetracycline resistance protein TetB signature 104 124 6.2E-10 T 28-03-2018 ALX04_RS01605 ed86c7cae2ba650cfd3f4ef796d9883b 500 PRINTS PR01036 Tetracycline resistance protein TetB signature 134 158 6.2E-10 T 28-03-2018 ALX04_RS01605 ed86c7cae2ba650cfd3f4ef796d9883b 500 Gene3D G3DSA:1.20.1250.20 248 497 1.9E-31 T 28-03-2018 ALX04_RS09735 6cb69a2325267e2cac7e1d7ae2774dd1 553 Pfam PF01609 Transposase DDE domain 257 508 8.9E-33 T 28-03-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 ALX04_RS09735 6cb69a2325267e2cac7e1d7ae2774dd1 553 Pfam PF05598 Transposase domain (DUF772) 45 101 1.7E-11 T 28-03-2018 IPR008490 Transposase InsH, N-terminal ALX04_RS09735 6cb69a2325267e2cac7e1d7ae2774dd1 553 Gene3D G3DSA:3.90.350.10 228 491 4.9E-8 T 28-03-2018 IPR014736 Transposase, Tn5-like, core ALX04_RS05590 a3a9d528c6372aa04d7baf1f34de5368 449 Pfam PF05525 Branched-chain amino acid transport protein 8 441 2.8E-135 T 28-03-2018 IPR004685 Branched-chain amino acid transport system II carrier protein GO:0015658|GO:0015803|GO:0016021 ALX04_RS05590 a3a9d528c6372aa04d7baf1f34de5368 449 TIGRFAM TIGR00796 livcs: branched-chain amino acid transport system II carrier protein 14 427 1.3E-118 T 28-03-2018 IPR004685 Branched-chain amino acid transport system II carrier protein GO:0015658|GO:0015803|GO:0016021 ALX04_RS11515 0df84dde447940d82fcf7d6ab66720f9 195 TIGRFAM TIGR02227 sigpep_I_bact: signal peptidase I 10 180 1.4E-41 T 28-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 ALX04_RS11515 0df84dde447940d82fcf7d6ab66720f9 195 SUPERFAMILY SSF51306 25 188 4.53E-46 T 28-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C ALX04_RS11515 0df84dde447940d82fcf7d6ab66720f9 195 ProSitePatterns PS00761 Signal peptidases I signature 3. 147 160 - T 28-03-2018 IPR019758 Peptidase S26A, signal peptidase I, conserved site GO:0008236|GO:0016021 ALX04_RS11515 0df84dde447940d82fcf7d6ab66720f9 195 Pfam PF00717 Peptidase S24-like 33 105 1.2E-12 T 28-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C ALX04_RS11515 0df84dde447940d82fcf7d6ab66720f9 195 Gene3D G3DSA:2.10.109.10 23 195 2.4E-37 T 28-03-2018 ALX04_RS11515 0df84dde447940d82fcf7d6ab66720f9 195 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 142 161 1.7E-18 T 28-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 ALX04_RS11515 0df84dde447940d82fcf7d6ab66720f9 195 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 81 93 1.7E-18 T 28-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 ALX04_RS11515 0df84dde447940d82fcf7d6ab66720f9 195 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 27 43 1.7E-18 T 28-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 ALX04_RS03585 f28d0081ae183d808c580d9dd71d0bdd 289 Pfam PF02645 Uncharacterised protein, DegV family COG1307 2 283 1.3E-88 T 28-03-2018 IPR003797 DegV ALX04_RS03585 f28d0081ae183d808c580d9dd71d0bdd 289 Gene3D G3DSA:3.30.1180.10 155 283 7.5E-33 T 28-03-2018 ALX04_RS03585 f28d0081ae183d808c580d9dd71d0bdd 289 TIGRFAM TIGR00762 DegV: EDD domain protein, DegV family 3 282 1.9E-99 T 28-03-2018 IPR003797 DegV ALX04_RS03585 f28d0081ae183d808c580d9dd71d0bdd 289 Gene3D G3DSA:3.40.50.10170 1 152 9.1E-49 T 28-03-2018 ALX04_RS03585 f28d0081ae183d808c580d9dd71d0bdd 289 SUPERFAMILY SSF82549 1 284 1.73E-92 T 28-03-2018 ALX04_RS08805 1cdffc05b2c51198e3969ab3b8aa8f22 540 SUPERFAMILY SSF52540 2 81 2.2E-42 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase ALX04_RS08805 1cdffc05b2c51198e3969ab3b8aa8f22 540 SUPERFAMILY SSF52540 125 250 2.2E-42 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase ALX04_RS08805 1cdffc05b2c51198e3969ab3b8aa8f22 540 SUPERFAMILY SSF52540 296 521 2.37E-39 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase ALX04_RS08805 1cdffc05b2c51198e3969ab3b8aa8f22 540 Pfam PF00005 ABC transporter 18 184 9.4E-22 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 ALX04_RS08805 1cdffc05b2c51198e3969ab3b8aa8f22 540 Pfam PF00005 ABC transporter 335 469 9.7E-13 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 ALX04_RS08805 1cdffc05b2c51198e3969ab3b8aa8f22 540 SMART SM00382 344 514 0.091 T 28-03-2018 IPR003593 AAA+ ATPase domain ALX04_RS08805 1cdffc05b2c51198e3969ab3b8aa8f22 540 SMART SM00382 26 231 4.2E-9 T 28-03-2018 IPR003593 AAA+ ATPase domain ALX04_RS08805 1cdffc05b2c51198e3969ab3b8aa8f22 540 Gene3D G3DSA:3.40.50.300 284 538 1.1E-39 T 28-03-2018 ALX04_RS08805 1cdffc05b2c51198e3969ab3b8aa8f22 540 Gene3D G3DSA:3.40.50.300 1 283 7.0E-53 T 28-03-2018 ALX04_RS08805 1cdffc05b2c51198e3969ab3b8aa8f22 540 Pfam PF12848 ABC transporter 224 309 1.2E-20 T 28-03-2018 IPR032781 ABC-transporter extension domain ALX04_RS05175 d103f201eb0f9a3ca1f9e79779950e59 491 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 304 489 4.4E-22 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 ALX04_RS05175 d103f201eb0f9a3ca1f9e79779950e59 491 SUPERFAMILY SSF161098 284 474 7.19E-47 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 ALX04_RS05175 d103f201eb0f9a3ca1f9e79779950e59 491 Gene3D G3DSA:3.40.190.10 8 163 7.2E-35 T 28-03-2018 ALX04_RS05175 d103f201eb0f9a3ca1f9e79779950e59 491 SMART SM00062 43 266 9.9E-42 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF ALX04_RS05175 d103f201eb0f9a3ca1f9e79779950e59 491 Gene3D G3DSA:1.10.3720.10 279 491 1.1E-44 T 28-03-2018 ALX04_RS05175 d103f201eb0f9a3ca1f9e79779950e59 491 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 283 383 2.2E-26 T 28-03-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 ALX04_RS05175 d103f201eb0f9a3ca1f9e79779950e59 491 Gene3D G3DSA:3.40.190.10 164 264 1.6E-6 T 28-03-2018 ALX04_RS05175 d103f201eb0f9a3ca1f9e79779950e59 491 SUPERFAMILY SSF53850 1 260 1.83E-54 T 28-03-2018 ALX04_RS05175 d103f201eb0f9a3ca1f9e79779950e59 491 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 44 256 2.9E-48 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF ALX04_RS13845 a835540453186cf1130e8a0e2a9ccfe6 180 Pfam PF00156 Phosphoribosyl transferase domain 16 159 2.9E-27 T 28-03-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 ALX04_RS13845 a835540453186cf1130e8a0e2a9ccfe6 180 Gene3D G3DSA:3.40.50.2020 1 180 1.8E-49 T 28-03-2018 ALX04_RS13845 a835540453186cf1130e8a0e2a9ccfe6 180 SUPERFAMILY SSF53271 2 178 1.1E-59 T 28-03-2018 IPR029057 Phosphoribosyltransferase-like ALX04_RS13845 a835540453186cf1130e8a0e2a9ccfe6 180 TIGRFAM TIGR01203 HGPRTase: hypoxanthine phosphoribosyltransferase 8 172 8.3E-62 T 28-03-2018 IPR005904 Hypoxanthine phosphoribosyl transferase GO:0004422|GO:0005737|GO:0006166 KEGG: 00230+2.4.2.8|KEGG: 00983+2.4.2.8|MetaCyc: PWY-6599|MetaCyc: PWY-6609|MetaCyc: PWY-6610|MetaCyc: PWY-6620 ALX04_RS13750 afba7c5f671be5e45aadbfe890407ff7 256 Gene3D G3DSA:3.40.50.300 2 222 5.3E-58 T 28-03-2018 ALX04_RS13750 afba7c5f671be5e45aadbfe890407ff7 256 SMART SM00382 33 213 6.6E-15 T 28-03-2018 IPR003593 AAA+ ATPase domain ALX04_RS13750 afba7c5f671be5e45aadbfe890407ff7 256 Pfam PF00005 ABC transporter 24 162 2.0E-34 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 ALX04_RS13750 afba7c5f671be5e45aadbfe890407ff7 256 SUPERFAMILY SSF52540 4 239 2.18E-68 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase ALX04_RS13750 afba7c5f671be5e45aadbfe890407ff7 256 ProSitePatterns PS00211 ABC transporters family signature. 135 149 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 ALX04_RS07095 eae70cac91eb3b14e88bd76360b1d5ad 242 SUPERFAMILY SSF52172 1 120 1.57E-33 T 28-03-2018 IPR011006 CheY-like superfamily ALX04_RS07095 eae70cac91eb3b14e88bd76360b1d5ad 242 SMART SM00862 159 234 3.5E-29 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 ALX04_RS07095 eae70cac91eb3b14e88bd76360b1d5ad 242 SUPERFAMILY SSF46894 141 235 1.62E-28 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 ALX04_RS07095 eae70cac91eb3b14e88bd76360b1d5ad 242 Pfam PF00072 Response regulator receiver domain 4 115 1.2E-24 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 ALX04_RS07095 eae70cac91eb3b14e88bd76360b1d5ad 242 Gene3D G3DSA:3.40.50.2300 1 130 1.4E-32 T 28-03-2018 ALX04_RS07095 eae70cac91eb3b14e88bd76360b1d5ad 242 SMART SM00448 1 114 1.8E-35 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 ALX04_RS07095 eae70cac91eb3b14e88bd76360b1d5ad 242 Pfam PF00486 Transcriptional regulatory protein, C terminal 164 234 2.8E-28 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 ALX04_RS07095 eae70cac91eb3b14e88bd76360b1d5ad 242 Gene3D G3DSA:1.10.10.10 131 241 1.2E-31 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS09480 7a33f914dfbed9a9b97d879093eec74a 131 Gene3D G3DSA:2.60.300.12 2 114 3.8E-29 T 28-03-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 ALX04_RS09480 7a33f914dfbed9a9b97d879093eec74a 131 SUPERFAMILY SSF89360 3 111 2.82E-25 T 28-03-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 ALX04_RS09480 7a33f914dfbed9a9b97d879093eec74a 131 Pfam PF01521 Iron-sulphur cluster biosynthesis 3 111 4.0E-22 T 28-03-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 ALX04_RS02855 c77b9910d02f7c6c6936ddd11f61c149 348 PIRSF PIRSF002465 1 338 7.1E-124 T 28-03-2018 IPR012281 Phospholipid biosynthesis protein, PlsX-like GO:0006633 ALX04_RS02855 c77b9910d02f7c6c6936ddd11f61c149 348 SUPERFAMILY SSF53659 3 329 2.59E-97 T 28-03-2018 ALX04_RS02855 c77b9910d02f7c6c6936ddd11f61c149 348 TIGRFAM TIGR00182 plsX: fatty acid/phospholipid synthesis protein PlsX 2 335 1.4E-113 T 28-03-2018 IPR012281 Phospholipid biosynthesis protein, PlsX-like GO:0006633 ALX04_RS02855 c77b9910d02f7c6c6936ddd11f61c149 348 Gene3D G3DSA:3.40.718.10 1 335 9.9E-99 T 28-03-2018 ALX04_RS02855 c77b9910d02f7c6c6936ddd11f61c149 348 Hamap MF_00019 Phosphate acyltransferase [plsX]. 1 338 138.62 T 28-03-2018 IPR012281 Phospholipid biosynthesis protein, PlsX-like GO:0006633 ALX04_RS02855 c77b9910d02f7c6c6936ddd11f61c149 348 Pfam PF02504 Fatty acid synthesis protein 2 322 4.3E-107 T 28-03-2018 IPR003664 Fatty acid synthesis PlsX protein GO:0003824|GO:0006633|GO:0016747 ALX04_RS01450 126cd8665004294ffea79b55e4feb23a 701 SUPERFAMILY SSF53649 251 652 3.49E-82 T 28-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 ALX04_RS01450 126cd8665004294ffea79b55e4feb23a 701 PIRSF PIRSF005091 3 634 5.0E-196 T 28-03-2018 IPR012160 Lipoteichoic acid synthase-like ALX04_RS01450 126cd8665004294ffea79b55e4feb23a 701 Pfam PF00884 Sulfatase 253 545 3.5E-35 T 28-03-2018 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 ALX04_RS01450 126cd8665004294ffea79b55e4feb23a 701 Gene3D G3DSA:3.40.720.10 245 555 2.9E-39 T 28-03-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 ALX04_RS01110 929b2eb43fa49e91f16b047ba1ca5c3b 257 SUPERFAMILY SSF89550 6 213 8.04E-19 T 28-03-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 ALX04_RS01110 929b2eb43fa49e91f16b047ba1ca5c3b 257 PIRSF PIRSF016557 6 257 1.7E-100 T 28-03-2018 IPR016667 Capsular polysaccharide synthesis, CpsB/CapC GO:0004725|GO:0030145 ALX04_RS01110 929b2eb43fa49e91f16b047ba1ca5c3b 257 Gene3D G3DSA:3.20.20.140 5 245 1.1E-28 T 28-03-2018 ALX04_RS00805 51127311be2eae8ee8c74fdf9eec124d 577 SUPERFAMILY SSF90123 12 307 1.83E-46 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 ALX04_RS00805 51127311be2eae8ee8c74fdf9eec124d 577 ProSitePatterns PS00211 ABC transporters family signature. 474 488 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 ALX04_RS00805 51127311be2eae8ee8c74fdf9eec124d 577 SUPERFAMILY SSF52540 327 571 4.26E-68 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase ALX04_RS00805 51127311be2eae8ee8c74fdf9eec124d 577 SMART SM00382 360 549 2.2E-14 T 28-03-2018 IPR003593 AAA+ ATPase domain ALX04_RS00805 51127311be2eae8ee8c74fdf9eec124d 577 Pfam PF00664 ABC transporter transmembrane region 18 280 1.2E-27 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 ALX04_RS00805 51127311be2eae8ee8c74fdf9eec124d 577 Gene3D G3DSA:1.20.1560.10 7 318 4.9E-36 T 28-03-2018 ALX04_RS00805 51127311be2eae8ee8c74fdf9eec124d 577 TIGRFAM TIGR02857 CydD: thiol reductant ABC exporter, CydD subunit 13 545 8.1E-166 T 28-03-2018 IPR014216 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease/ATP-binding protein CydD GO:0005524|GO:0016020|GO:0042883 ALX04_RS00805 51127311be2eae8ee8c74fdf9eec124d 577 Pfam PF00005 ABC transporter 351 503 3.4E-26 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 ALX04_RS00805 51127311be2eae8ee8c74fdf9eec124d 577 Gene3D G3DSA:3.40.50.300 319 574 9.7E-66 T 28-03-2018 ALX04_RS10170 c286ef55123c7a1e1ebc0d3ea00dc777 370 SUPERFAMILY SSF110738 1 367 3.14E-104 T 28-03-2018 IPR004381 Glycerate kinase GO:0008887|GO:0031388 ALX04_RS10170 c286ef55123c7a1e1ebc0d3ea00dc777 370 TIGRFAM TIGR00045 TIGR00045: glycerate kinase 4 368 2.9E-104 T 28-03-2018 IPR004381 Glycerate kinase GO:0008887|GO:0031388 ALX04_RS10170 c286ef55123c7a1e1ebc0d3ea00dc777 370 PIRSF PIRSF006078 1 370 3.8E-105 T 28-03-2018 IPR004381 Glycerate kinase GO:0008887|GO:0031388 ALX04_RS10170 c286ef55123c7a1e1ebc0d3ea00dc777 370 Gene3D G3DSA:3.90.1510.10 40 269 1.8E-70 T 28-03-2018 IPR018193 Glycerate kinase, flavodoxin-like domain GO:0008887|GO:0031388 ALX04_RS10170 c286ef55123c7a1e1ebc0d3ea00dc777 370 Pfam PF02595 Glycerate kinase family 4 367 1.7E-113 T 28-03-2018 IPR004381 Glycerate kinase GO:0008887|GO:0031388 ALX04_RS13610 42107f5d5105f996ab8657d240f80e01 310 Gene3D G3DSA:3.30.930.10 47 309 4.3E-32 T 28-03-2018 ALX04_RS13610 42107f5d5105f996ab8657d240f80e01 310 Pfam PF03099 Biotin/lipoate A/B protein ligase family 106 214 2.4E-13 T 28-03-2018 IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain GO:0006464 ALX04_RS13610 42107f5d5105f996ab8657d240f80e01 310 SUPERFAMILY SSF55681 59 283 2.65E-53 T 28-03-2018 ALX04_RS14745 2b72340bade03365d504acb264f4fdd5 343 SUPERFAMILY SSF46785 19 82 3.17E-11 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS14745 2b72340bade03365d504acb264f4fdd5 343 Pfam PF04198 Putative sugar-binding domain 92 342 2.3E-61 T 28-03-2018 IPR007324 Sugar-binding domain, putative GO:0030246 ALX04_RS14745 2b72340bade03365d504acb264f4fdd5 343 Gene3D G3DSA:1.10.10.10 17 87 1.3E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS14745 2b72340bade03365d504acb264f4fdd5 343 SUPERFAMILY SSF100950 97 342 1.67E-64 T 28-03-2018 ALX04_RS14745 2b72340bade03365d504acb264f4fdd5 343 Gene3D G3DSA:3.40.50.1360 94 341 1.4E-35 T 28-03-2018 ALX04_RS02035 ac40c1c4ee5cff266bdb9bed99746a60 326 Gene3D G3DSA:2.40.50.140 3 98 7.0E-9 T 28-03-2018 ALX04_RS02035 ac40c1c4ee5cff266bdb9bed99746a60 326 Pfam PF01966 HD domain 161 280 1.3E-9 T 28-03-2018 IPR006674 HD domain ALX04_RS02035 ac40c1c4ee5cff266bdb9bed99746a60 326 TIGRFAM TIGR00277 HDIG: HDIG domain 158 202 4.2E-7 T 28-03-2018 IPR006675 HDIG domain ALX04_RS02035 ac40c1c4ee5cff266bdb9bed99746a60 326 Pfam PF01336 OB-fold nucleic acid binding domain 28 88 2.5E-7 T 28-03-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 ALX04_RS02035 ac40c1c4ee5cff266bdb9bed99746a60 326 Gene3D G3DSA:1.10.3210.10 147 310 3.3E-12 T 28-03-2018 ALX04_RS02035 ac40c1c4ee5cff266bdb9bed99746a60 326 SMART SM00471 156 290 2.2E-4 T 28-03-2018 IPR003607 HD/PDEase domain ALX04_RS02035 ac40c1c4ee5cff266bdb9bed99746a60 326 SUPERFAMILY SSF109604 148 281 1.77E-12 T 28-03-2018 ALX04_RS12655 c8a04ace2790a8aee66a429f3eebb5ef 340 SUPERFAMILY SSF53613 1 324 7.17E-54 T 28-03-2018 IPR029056 Ribokinase-like ALX04_RS12655 c8a04ace2790a8aee66a429f3eebb5ef 340 Gene3D G3DSA:3.40.1190.20 1 333 1.2E-39 T 28-03-2018 IPR029056 Ribokinase-like ALX04_RS12655 c8a04ace2790a8aee66a429f3eebb5ef 340 Pfam PF00294 pfkB family carbohydrate kinase 2 220 2.0E-18 T 28-03-2018 IPR011611 Carbohydrate kinase PfkB ALX04_RS12655 c8a04ace2790a8aee66a429f3eebb5ef 340 Pfam PF00294 pfkB family carbohydrate kinase 259 311 6.9E-6 T 28-03-2018 IPR011611 Carbohydrate kinase PfkB ALX04_RS10305 7db2516221a73cb0552083832152045e 382 Gene3D G3DSA:3.20.20.20 99 376 4.8E-79 T 28-03-2018 ALX04_RS10305 7db2516221a73cb0552083832152045e 382 SUPERFAMILY SSF51717 107 374 4.45E-73 T 28-03-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 ALX04_RS10305 7db2516221a73cb0552083832152045e 382 Pfam PF00809 Pterin binding enzyme 122 357 5.9E-56 T 28-03-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 ALX04_RS10305 7db2516221a73cb0552083832152045e 382 TIGRFAM TIGR01496 DHPS: dihydropteroate synthase 119 369 5.6E-75 T 28-03-2018 IPR006390 Dihydropteroate synthase GO:0004156|GO:0009396 KEGG: 00790+2.5.1.15|MetaCyc: PWY-6614 ALX04_RS10305 7db2516221a73cb0552083832152045e 382 ProSitePatterns PS00792 Dihydropteroate synthase signature 1. 120 135 - T 28-03-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 ALX04_RS12240 e6ea075931e78d5e1135ffa3f226a25a 264 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 154 173 6.3E-5 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR ALX04_RS12240 e6ea075931e78d5e1135ffa3f226a25a 264 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 81 92 6.3E-5 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR ALX04_RS12240 e6ea075931e78d5e1135ffa3f226a25a 264 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 134 142 6.3E-5 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR ALX04_RS12240 e6ea075931e78d5e1135ffa3f226a25a 264 Pfam PF00106 short chain dehydrogenase 8 196 3.0E-42 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR ALX04_RS12240 e6ea075931e78d5e1135ffa3f226a25a 264 SUPERFAMILY SSF51735 1 260 4.42E-63 T 28-03-2018 IPR016040 NAD(P)-binding domain ALX04_RS12240 e6ea075931e78d5e1135ffa3f226a25a 264 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 223 243 1.1E-24 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR ALX04_RS12240 e6ea075931e78d5e1135ffa3f226a25a 264 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 81 92 1.1E-24 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR ALX04_RS12240 e6ea075931e78d5e1135ffa3f226a25a 264 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 175 192 1.1E-24 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR ALX04_RS12240 e6ea075931e78d5e1135ffa3f226a25a 264 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 154 173 1.1E-24 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR ALX04_RS12240 e6ea075931e78d5e1135ffa3f226a25a 264 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 128 144 1.1E-24 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR ALX04_RS12240 e6ea075931e78d5e1135ffa3f226a25a 264 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 1.1E-24 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR ALX04_RS12240 e6ea075931e78d5e1135ffa3f226a25a 264 Gene3D G3DSA:3.40.50.720 2 264 1.7E-58 T 28-03-2018 ALX04_RS00565 da4f5c009214fc123b2c4781c9f6fa6e 262 Hamap MF_00171 tRNA pseudouridine synthase A [truA]. 3 250 35.321 T 28-03-2018 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 ALX04_RS00565 da4f5c009214fc123b2c4781c9f6fa6e 262 Gene3D G3DSA:3.30.70.580 1 109 3.3E-31 T 28-03-2018 ALX04_RS00565 da4f5c009214fc123b2c4781c9f6fa6e 262 Pfam PF01416 tRNA pseudouridine synthase 10 108 4.6E-11 T 28-03-2018 IPR020097 Pseudouridine synthase I, TruA, alpha/beta domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 ALX04_RS00565 da4f5c009214fc123b2c4781c9f6fa6e 262 Pfam PF01416 tRNA pseudouridine synthase 148 251 3.6E-26 T 28-03-2018 IPR020097 Pseudouridine synthase I, TruA, alpha/beta domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 ALX04_RS00565 da4f5c009214fc123b2c4781c9f6fa6e 262 SUPERFAMILY SSF55120 3 254 1.02E-78 T 28-03-2018 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 ALX04_RS00565 da4f5c009214fc123b2c4781c9f6fa6e 262 PIRSF PIRSF001430 2 261 1.5E-76 T 28-03-2018 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 ALX04_RS00565 da4f5c009214fc123b2c4781c9f6fa6e 262 TIGRFAM TIGR00071 hisT_truA: tRNA pseudouridine(38-40) synthase 6 245 3.4E-59 T 28-03-2018 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 ALX04_RS00565 da4f5c009214fc123b2c4781c9f6fa6e 262 Gene3D G3DSA:3.30.70.660 110 249 2.2E-34 T 28-03-2018 IPR020095 Pseudouridine synthase I, TruA, C-terminal GO:0001522|GO:0003723|GO:0009451|GO:0009982 ALX04_RS09885 38d81db3561081fb87e490f70b48fe24 366 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 70 85 1.1E-35 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 ALX04_RS09885 38d81db3561081fb87e490f70b48fe24 366 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 5 25 1.1E-35 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 ALX04_RS09885 38d81db3561081fb87e490f70b48fe24 366 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 26 44 1.1E-35 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 ALX04_RS09885 38d81db3561081fb87e490f70b48fe24 366 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 87 105 1.1E-35 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 ALX04_RS09885 38d81db3561081fb87e490f70b48fe24 366 Gene3D G3DSA:3.10.20.30 266 365 3.6E-46 T 28-03-2018 IPR012675 Beta-grasp domain ALX04_RS09885 38d81db3561081fb87e490f70b48fe24 366 Gene3D G3DSA:1.10.150.300 110 200 1.8E-30 T 28-03-2018 IPR023192 TGS-like domain Reactome: R-HSA-114608 ALX04_RS09885 38d81db3561081fb87e490f70b48fe24 366 SUPERFAMILY SSF81271 282 366 2.62E-35 T 28-03-2018 IPR012676 TGS-like KEGG: 00970+6.1.1.3 ALX04_RS09885 38d81db3561081fb87e490f70b48fe24 366 Pfam PF01926 50S ribosome-binding GTPase 5 124 1.6E-24 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 ALX04_RS09885 38d81db3561081fb87e490f70b48fe24 366 TIGRFAM TIGR00092 TIGR00092: GTP-binding protein YchF 1 366 8.3E-155 T 28-03-2018 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 Reactome: R-HSA-114608 ALX04_RS09885 38d81db3561081fb87e490f70b48fe24 366 Gene3D G3DSA:1.20.120.430 2 90 4.7E-7 T 28-03-2018 ALX04_RS09885 38d81db3561081fb87e490f70b48fe24 366 PIRSF PIRSF006641 1 366 1.7E-156 T 28-03-2018 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 Reactome: R-HSA-114608 ALX04_RS09885 38d81db3561081fb87e490f70b48fe24 366 Pfam PF06071 Protein of unknown function (DUF933) 282 365 9.8E-40 T 28-03-2018 IPR013029 Domain of unknown function DUF933 Reactome: R-HSA-114608 ALX04_RS09885 38d81db3561081fb87e490f70b48fe24 366 Hamap MF_00944 Ribosome-binding ATPase YchF [ychF]. 2 366 44.929 T 28-03-2018 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 Reactome: R-HSA-114608 ALX04_RS09885 38d81db3561081fb87e490f70b48fe24 366 SUPERFAMILY SSF52540 3 304 1.04E-85 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase ALX04_RS11775 3585b6b67529ab2795a9bb84cdca7b87 122 Pfam PF01242 6-pyruvoyl tetrahydropterin synthase 13 116 1.1E-14 T 28-03-2018 IPR007115 6-pyruvoyl tetrahydropterin synthase/QueD family protein Reactome: R-HSA-1474151 ALX04_RS11775 3585b6b67529ab2795a9bb84cdca7b87 122 Gene3D G3DSA:3.30.479.10 1 120 1.6E-14 T 28-03-2018 ALX04_RS11775 3585b6b67529ab2795a9bb84cdca7b87 122 TIGRFAM TIGR03112 6_pyr_pter_rel: 6-pyruvoyl tetrahydropterin synthase-related domain 8 118 1.5E-37 T 28-03-2018 IPR017543 6-pyruvoyl tetrahydropterin synthase, predicted, bacteria ALX04_RS11775 3585b6b67529ab2795a9bb84cdca7b87 122 SUPERFAMILY SSF55620 5 116 4.78E-18 T 28-03-2018 ALX04_RS12480 58c55d0814bb3ff0228b320f115bb478 116 Pfam PF02537 CrcB-like protein, Camphor Resistance (CrcB) 8 113 8.9E-21 T 28-03-2018 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 ALX04_RS12480 58c55d0814bb3ff0228b320f115bb478 116 Hamap MF_00454 Putative fluoride ion transporter CrcB [crcB]. 5 115 17.032 T 28-03-2018 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 ALX04_RS05455 bf2a9bd874db32d0c7365dc21c9c4589 184 Gene3D G3DSA:3.90.79.10 1 182 9.1E-36 T 28-03-2018 ALX04_RS05455 bf2a9bd874db32d0c7365dc21c9c4589 184 PRINTS PR00502 NUDIX hydrolase family signature 85 100 3.6E-5 T 28-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 ALX04_RS05455 bf2a9bd874db32d0c7365dc21c9c4589 184 PRINTS PR00502 NUDIX hydrolase family signature 71 85 3.6E-5 T 28-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 ALX04_RS05455 bf2a9bd874db32d0c7365dc21c9c4589 184 ProSitePatterns PS00893 Nudix box signature. 76 97 - T 28-03-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 ALX04_RS05455 bf2a9bd874db32d0c7365dc21c9c4589 184 SUPERFAMILY SSF55811 7 177 4.74E-41 T 28-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 ALX04_RS05455 bf2a9bd874db32d0c7365dc21c9c4589 184 Pfam PF00293 NUDIX domain 41 151 7.5E-14 T 28-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 ALX04_RS02360 06b684f6be88c0733661c7c949e3a47d 420 Gene3D G3DSA:1.10.3710.10 327 420 1.5E-16 T 28-03-2018 ALX04_RS02360 06b684f6be88c0733661c7c949e3a47d 420 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 44 148 4.7E-14 T 28-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 ALX04_RS02360 06b684f6be88c0733661c7c949e3a47d 420 SUPERFAMILY SSF52540 5 210 7.71E-42 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase ALX04_RS02360 06b684f6be88c0733661c7c949e3a47d 420 Pfam PF16193 AAA C-terminal domain 174 243 5.5E-13 T 28-03-2018 IPR032423 AAA C-terminal domain ALX04_RS02360 06b684f6be88c0733661c7c949e3a47d 420 Gene3D G3DSA:1.10.8.60 140 220 4.7E-20 T 28-03-2018 ALX04_RS02360 06b684f6be88c0733661c7c949e3a47d 420 SMART SM00382 40 151 6.3E-13 T 28-03-2018 IPR003593 AAA+ ATPase domain ALX04_RS02360 06b684f6be88c0733661c7c949e3a47d 420 Gene3D G3DSA:3.40.50.300 2 139 1.7E-28 T 28-03-2018 ALX04_RS02360 06b684f6be88c0733661c7c949e3a47d 420 Gene3D G3DSA:1.20.272.10 229 322 7.1E-20 T 28-03-2018 ALX04_RS02360 06b684f6be88c0733661c7c949e3a47d 420 Pfam PF12002 MgsA AAA+ ATPase C terminal 245 408 1.4E-40 T 28-03-2018 IPR021886 MgsA AAA+ ATPase C-terminal ALX04_RS02360 06b684f6be88c0733661c7c949e3a47d 420 SUPERFAMILY SSF48019 231 413 5.5E-46 T 28-03-2018 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 ALX04_RS07460 9089e0e884c2ed86e1b6daf8a76c4519 339 Gene3D G3DSA:3.40.50.720 1 131 3.5E-30 T 28-03-2018 ALX04_RS07460 9089e0e884c2ed86e1b6daf8a76c4519 339 SUPERFAMILY SSF51735 2 193 1.25E-42 T 28-03-2018 IPR016040 NAD(P)-binding domain ALX04_RS07460 9089e0e884c2ed86e1b6daf8a76c4519 339 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 3 116 4.7E-19 T 28-03-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 ALX04_RS07460 9089e0e884c2ed86e1b6daf8a76c4519 339 Gene3D G3DSA:3.30.360.10 132 339 6.5E-23 T 28-03-2018 ALX04_RS07460 9089e0e884c2ed86e1b6daf8a76c4519 339 Pfam PF02894 Oxidoreductase family, C-terminal alpha/beta domain 133 224 1.1E-5 T 28-03-2018 IPR004104 Oxidoreductase, C-terminal GO:0008152|GO:0016491|GO:0055114 ALX04_RS12440 a0dee7f6a66e3f579ecbfa1478a768d6 357 Gene3D G3DSA:3.40.640.10 15 254 6.0E-28 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 ALX04_RS12440 a0dee7f6a66e3f579ecbfa1478a768d6 357 Pfam PF00266 Aminotransferase class-V 3 345 4.5E-50 T 28-03-2018 IPR000192 Aminotransferase class V domain ALX04_RS12440 a0dee7f6a66e3f579ecbfa1478a768d6 357 Hamap MF_00160 Phosphoserine aminotransferase [serC]. 1 356 47.459 T 28-03-2018 IPR022278 Phosphoserine aminotransferase GO:0004648|GO:0006564 KEGG: 00260+2.6.1.52|KEGG: 00680+2.6.1.52|KEGG: 00750+2.6.1.52|Reactome: R-HSA-977347 ALX04_RS12440 a0dee7f6a66e3f579ecbfa1478a768d6 357 PIRSF PIRSF000525 1 357 4.9E-141 T 28-03-2018 IPR022278 Phosphoserine aminotransferase GO:0004648|GO:0006564 KEGG: 00260+2.6.1.52|KEGG: 00680+2.6.1.52|KEGG: 00750+2.6.1.52|Reactome: R-HSA-977347 ALX04_RS12440 a0dee7f6a66e3f579ecbfa1478a768d6 357 ProSitePatterns PS00595 Aminotransferases class-V pyridoxal-phosphate attachment site. 185 204 - T 28-03-2018 IPR020578 Aminotransferase class-V, pyridoxal-phosphate binding site ALX04_RS12440 a0dee7f6a66e3f579ecbfa1478a768d6 357 SUPERFAMILY SSF53383 3 354 1.1E-105 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase ALX04_RS12440 a0dee7f6a66e3f579ecbfa1478a768d6 357 Gene3D G3DSA:3.90.1150.10 255 355 2.9E-33 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 ALX04_RS12440 a0dee7f6a66e3f579ecbfa1478a768d6 357 TIGRFAM TIGR01364 serC_1: phosphoserine transaminase 3 356 2.5E-139 T 28-03-2018 IPR022278 Phosphoserine aminotransferase GO:0004648|GO:0006564 KEGG: 00260+2.6.1.52|KEGG: 00680+2.6.1.52|KEGG: 00750+2.6.1.52|Reactome: R-HSA-977347 ALX04_RS12570 5407b91036d586c202c77936a5bbf153 149 Gene3D G3DSA:3.40.930.10 1 149 7.5E-32 T 28-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 ALX04_RS12570 5407b91036d586c202c77936a5bbf153 149 ProSitePatterns PS00372 PTS EIIA domains phosphorylation site signature 2. 47 63 - T 28-03-2018 IPR002178 PTS EIIA type-2 domain ALX04_RS12570 5407b91036d586c202c77936a5bbf153 149 SUPERFAMILY SSF55804 2 147 1.44E-37 T 28-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 ALX04_RS12570 5407b91036d586c202c77936a5bbf153 149 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 4 147 4.5E-32 T 28-03-2018 IPR002178 PTS EIIA type-2 domain ALX04_RS08720 cfc77a43e32189a8e9e4e3505795c04a 390 Gene3D G3DSA:3.90.1150.10 275 386 2.2E-18 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 ALX04_RS08720 cfc77a43e32189a8e9e4e3505795c04a 390 SUPERFAMILY SSF53383 1 381 4.13E-83 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase ALX04_RS08720 cfc77a43e32189a8e9e4e3505795c04a 390 Gene3D G3DSA:3.90.1150.10 2 73 1.2E-9 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 ALX04_RS08720 cfc77a43e32189a8e9e4e3505795c04a 390 Pfam PF00155 Aminotransferase class I and II 35 373 9.5E-29 T 28-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 ALX04_RS08720 cfc77a43e32189a8e9e4e3505795c04a 390 TIGRFAM TIGR04350 C_S_lyase_PatB: putative C-S lyase 5 382 5.4E-120 T 28-03-2018 IPR027619 Putative C-S lyase KEGG: 00270+4.4.1.8|KEGG: 00450+4.4.1.8|MetaCyc: PWY-6936 ALX04_RS08720 cfc77a43e32189a8e9e4e3505795c04a 390 Gene3D G3DSA:3.40.640.10 74 274 9.1E-30 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 ALX04_RS01375 aaf7d921f48c6413ce9ba3158bf7adba 344 SUPERFAMILY SSF161098 136 328 2.88E-28 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 ALX04_RS01375 aaf7d921f48c6413ce9ba3158bf7adba 344 Gene3D G3DSA:1.10.3720.10 39 332 5.2E-45 T 28-03-2018 ALX04_RS01375 aaf7d921f48c6413ce9ba3158bf7adba 344 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 159 343 2.0E-32 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 ALX04_RS01375 aaf7d921f48c6413ce9ba3158bf7adba 344 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 35 87 1.7E-12 T 28-03-2018 IPR025966 Oligopeptide transport permease C-like, N-terminal domain ALX04_RS15690 92b7029deb0136df9f40f517b8a17e41 195 Pfam PF00589 Phage integrase family 16 179 2.9E-17 T 28-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 ALX04_RS15690 92b7029deb0136df9f40f517b8a17e41 195 SUPERFAMILY SSF56349 10 193 2.94E-32 T 28-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 ALX04_RS15690 92b7029deb0136df9f40f517b8a17e41 195 Gene3D G3DSA:1.10.443.10 13 189 1.7E-24 T 28-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 ALX04_RS14760 0a2a3d85d2aacc0129b9c25cf71f9649 252 TIGRFAM TIGR00419 tim: triose-phosphate isomerase 5 241 8.5E-60 T 28-03-2018 IPR000652 Triosephosphate isomerase GO:0004807|GO:0008152 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 ALX04_RS14760 0a2a3d85d2aacc0129b9c25cf71f9649 252 Hamap MF_00147_B Triosephosphate isomerase [tpiA]. 2 250 40.327 T 28-03-2018 IPR022896 Triosephosphate isomerase, bacterial/eukaryotic GO:0004807|GO:0006096 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 ALX04_RS14760 0a2a3d85d2aacc0129b9c25cf71f9649 252 Pfam PF00121 Triosephosphate isomerase 5 247 5.0E-93 T 28-03-2018 IPR000652 Triosephosphate isomerase GO:0004807|GO:0008152 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 ALX04_RS14760 0a2a3d85d2aacc0129b9c25cf71f9649 252 Gene3D G3DSA:3.20.20.70 1 252 1.1E-102 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 ALX04_RS14760 0a2a3d85d2aacc0129b9c25cf71f9649 252 SUPERFAMILY SSF51351 2 249 6.54E-94 T 28-03-2018 IPR000652 Triosephosphate isomerase GO:0004807|GO:0008152 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 ALX04_RS14760 0a2a3d85d2aacc0129b9c25cf71f9649 252 ProSitePatterns PS00171 Triosephosphate isomerase active site. 165 175 - T 28-03-2018 IPR020861 Triosephosphate isomerase, active site GO:0004807 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 ALX04_RS08820 e4f51ca19a7fb34ad0c411fc26c3277c 835 Gene3D G3DSA:1.20.1580.10 584 721 8.8E-41 T 28-03-2018 ALX04_RS08820 e4f51ca19a7fb34ad0c411fc26c3277c 835 Gene3D G3DSA:3.40.50.300 507 576 0.0031 T 28-03-2018 ALX04_RS08820 e4f51ca19a7fb34ad0c411fc26c3277c 835 SUPERFAMILY SSF52540 510 803 9.89E-36 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase ALX04_RS08820 e4f51ca19a7fb34ad0c411fc26c3277c 835 SUPERFAMILY SSF52540 10 58 1.95E-31 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase ALX04_RS08820 e4f51ca19a7fb34ad0c411fc26c3277c 835 SUPERFAMILY SSF52540 309 462 1.95E-31 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase ALX04_RS08820 e4f51ca19a7fb34ad0c411fc26c3277c 835 Gene3D G3DSA:1.20.1580.10 109 379 1.1E-55 T 28-03-2018 ALX04_RS08820 e4f51ca19a7fb34ad0c411fc26c3277c 835 Gene3D G3DSA:3.40.50.300 5 44 0.026 T 28-03-2018 ALX04_RS08820 e4f51ca19a7fb34ad0c411fc26c3277c 835 Gene3D G3DSA:3.40.50.300 45 108 0.02 T 28-03-2018 ALX04_RS07625 64e5c6ce3ac1a59b446eb79b488ac7a1 291 Pfam PF13240 zinc-ribbon domain 7 27 1.0E-8 T 28-03-2018 IPR026870 Zinc-ribbon domain Reactome: R-HSA-202670 ALX04_RS07625 64e5c6ce3ac1a59b446eb79b488ac7a1 291 Gene3D G3DSA:2.20.70.10 19 42 0.022 T 28-03-2018 ALX04_RS07895 98634902cd5cad442b2a501817941506 192 SUPERFAMILY SSF53328 4 189 1.96E-59 T 28-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 ALX04_RS07895 98634902cd5cad442b2a501817941506 192 Hamap MF_01930 Phosphoribosylglycinamide formyltransferase [purN]. 4 189 28.789 T 28-03-2018 IPR004607 Phosphoribosylglycinamide formyltransferase GO:0004644|GO:0006189 KEGG: 00230+2.1.2.2|KEGG: 00670+2.1.2.2|MetaCyc: PWY-6121|MetaCyc: PWY-6613|Reactome: R-HSA-73817 ALX04_RS07895 98634902cd5cad442b2a501817941506 192 Pfam PF00551 Formyl transferase 4 183 5.7E-54 T 28-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 ALX04_RS07895 98634902cd5cad442b2a501817941506 192 Gene3D G3DSA:3.40.50.170 1 192 5.4E-61 T 28-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 ALX04_RS07895 98634902cd5cad442b2a501817941506 192 TIGRFAM TIGR00639 PurN: phosphoribosylglycinamide formyltransferase 4 189 2.6E-62 T 28-03-2018 IPR004607 Phosphoribosylglycinamide formyltransferase GO:0004644|GO:0006189 KEGG: 00230+2.1.2.2|KEGG: 00670+2.1.2.2|MetaCyc: PWY-6121|MetaCyc: PWY-6613|Reactome: R-HSA-73817 ALX04_RS10345 7a25be2b18f6aa079f50ffda03a8c425 302 SUPERFAMILY SSF53807 35 296 2.4E-63 T 28-03-2018 ALX04_RS10345 7a25be2b18f6aa079f50ffda03a8c425 302 Gene3D G3DSA:3.40.50.1980 25 184 1.5E-34 T 28-03-2018 ALX04_RS10345 7a25be2b18f6aa079f50ffda03a8c425 302 PRINTS PR00690 Adhesin family signature 81 98 9.1E-6 T 28-03-2018 IPR006128 Adhesion lipoprotein GO:0007155 ALX04_RS10345 7a25be2b18f6aa079f50ffda03a8c425 302 PRINTS PR00690 Adhesin family signature 36 54 9.1E-6 T 28-03-2018 IPR006128 Adhesion lipoprotein GO:0007155 ALX04_RS10345 7a25be2b18f6aa079f50ffda03a8c425 302 PRINTS PR00690 Adhesin family signature 68 81 9.1E-6 T 28-03-2018 IPR006128 Adhesion lipoprotein GO:0007155 ALX04_RS10345 7a25be2b18f6aa079f50ffda03a8c425 302 Gene3D G3DSA:3.40.50.1980 185 297 1.8E-19 T 28-03-2018 ALX04_RS10345 7a25be2b18f6aa079f50ffda03a8c425 302 Pfam PF01297 Zinc-uptake complex component A periplasmic 39 295 6.5E-44 T 28-03-2018 IPR006127 Periplasmic solute binding protein, ZnuA-like GO:0030001|GO:0046872 ALX04_RS11060 5bbfc83136e7ac348511e6ef75a29632 763 SMART SM00900 12 86 4.3E-12 T 28-03-2018 IPR007329 FMN-binding GO:0010181|GO:0016020 ALX04_RS11060 5bbfc83136e7ac348511e6ef75a29632 763 SUPERFAMILY SSF52218 579 749 4.89E-40 T 28-03-2018 IPR029039 Flavoprotein-like domain ALX04_RS11060 5bbfc83136e7ac348511e6ef75a29632 763 Gene3D G3DSA:3.50.50.60 104 362 5.9E-22 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ALX04_RS11060 5bbfc83136e7ac348511e6ef75a29632 763 Pfam PF00890 FAD binding domain 107 543 2.6E-29 T 28-03-2018 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 ALX04_RS11060 5bbfc83136e7ac348511e6ef75a29632 763 SUPERFAMILY SSF51905 99 345 6.76E-39 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ALX04_RS11060 5bbfc83136e7ac348511e6ef75a29632 763 SUPERFAMILY SSF51905 507 571 6.76E-39 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ALX04_RS11060 5bbfc83136e7ac348511e6ef75a29632 763 SUPERFAMILY SSF56425 358 507 8.79E-22 T 28-03-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 ALX04_RS11060 5bbfc83136e7ac348511e6ef75a29632 763 Pfam PF04205 FMN-binding domain 12 83 5.3E-10 T 28-03-2018 IPR007329 FMN-binding GO:0010181|GO:0016020 ALX04_RS11060 5bbfc83136e7ac348511e6ef75a29632 763 Pfam PF03358 NADPH-dependent FMN reductase 579 723 3.6E-33 T 28-03-2018 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 ALX04_RS11060 5bbfc83136e7ac348511e6ef75a29632 763 Gene3D G3DSA:3.90.700.10 363 505 3.6E-30 T 28-03-2018 ALX04_RS11060 5bbfc83136e7ac348511e6ef75a29632 763 Gene3D G3DSA:3.40.50.360 576 761 6.8E-30 T 28-03-2018 IPR029039 Flavoprotein-like domain ALX04_RS06480 685f3ba9a57a4b153095094e135ba98c 192 Gene3D G3DSA:3.30.60.20 140 192 2.6E-20 T 28-03-2018 ALX04_RS06480 685f3ba9a57a4b153095094e135ba98c 192 SUPERFAMILY SSF52540 2 140 1.86E-38 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase ALX04_RS06480 685f3ba9a57a4b153095094e135ba98c 192 PIRSF PIRSF035805 1 191 1.3E-57 T 28-03-2018 IPR001267 Thymidine kinase GO:0004797|GO:0005524 KEGG: 00240+2.7.1.21|KEGG: 00983+2.7.1.21|MetaCyc: PWY-7199|Reactome: R-HSA-539107|Reactome: R-HSA-73614 ALX04_RS06480 685f3ba9a57a4b153095094e135ba98c 192 Pfam PF00265 Thymidine kinase 3 184 1.0E-50 T 28-03-2018 IPR001267 Thymidine kinase GO:0004797|GO:0005524 KEGG: 00240+2.7.1.21|KEGG: 00983+2.7.1.21|MetaCyc: PWY-7199|Reactome: R-HSA-539107|Reactome: R-HSA-73614 ALX04_RS06480 685f3ba9a57a4b153095094e135ba98c 192 Hamap MF_00124 Thymidine kinase [tdk]. 1 187 33.651 T 28-03-2018 IPR001267 Thymidine kinase GO:0004797|GO:0005524 KEGG: 00240+2.7.1.21|KEGG: 00983+2.7.1.21|MetaCyc: PWY-7199|Reactome: R-HSA-539107|Reactome: R-HSA-73614 ALX04_RS06480 685f3ba9a57a4b153095094e135ba98c 192 Gene3D G3DSA:3.40.50.300 2 139 6.7E-44 T 28-03-2018 ALX04_RS06480 685f3ba9a57a4b153095094e135ba98c 192 ProSitePatterns PS00603 Thymidine kinase cellular-type signature. 171 184 - T 28-03-2018 IPR020633 Thymidine kinase, conserved site GO:0004797|GO:0005524 KEGG: 00240+2.7.1.21|KEGG: 00983+2.7.1.21|MetaCyc: PWY-7199|Reactome: R-HSA-539107|Reactome: R-HSA-73614 ALX04_RS06480 685f3ba9a57a4b153095094e135ba98c 192 SUPERFAMILY SSF57716 140 188 4.28E-18 T 28-03-2018 ALX04_RS10475 6ec7f66d170e43339bd876c512879518 474 TIGRFAM TIGR00931 antiport_nhaC: Na+/H+ antiporter NhaC 11 457 2.1E-111 T 28-03-2018 IPR004770 Na+/H+ antiporter NhaC GO:0015297|GO:0016021 ALX04_RS10475 6ec7f66d170e43339bd876c512879518 474 Pfam PF03553 Na+/H+ antiporter family 164 453 6.5E-44 T 28-03-2018 IPR018461 Na+/H+ antiporter, NhaC-like, C-terminal GO:0016021 ALX04_RS06395 fa3c4014de469b76d87a7081150e73bd 184 SUPERFAMILY SSF55729 3 173 4.48E-43 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase ALX04_RS06395 fa3c4014de469b76d87a7081150e73bd 184 Gene3D G3DSA:3.40.630.30 3 182 2.9E-28 T 28-03-2018 ALX04_RS06395 fa3c4014de469b76d87a7081150e73bd 184 Pfam PF13302 Acetyltransferase (GNAT) domain 11 146 8.7E-20 T 28-03-2018 IPR000182 GNAT domain GO:0008080 ALX04_RS08740 0d9c9dfe82e1bc28e1ec9b68a9105d3b 583 ProSitePatterns PS00211 ABC transporters family signature. 474 488 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 ALX04_RS08740 0d9c9dfe82e1bc28e1ec9b68a9105d3b 583 SMART SM00382 362 548 2.3E-13 T 28-03-2018 IPR003593 AAA+ ATPase domain ALX04_RS08740 0d9c9dfe82e1bc28e1ec9b68a9105d3b 583 Gene3D G3DSA:3.40.50.300 323 578 2.2E-66 T 28-03-2018 ALX04_RS08740 0d9c9dfe82e1bc28e1ec9b68a9105d3b 583 SUPERFAMILY SSF52540 331 572 2.81E-81 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase ALX04_RS08740 0d9c9dfe82e1bc28e1ec9b68a9105d3b 583 Gene3D G3DSA:1.20.1560.10 2 322 2.6E-64 T 28-03-2018 ALX04_RS08740 0d9c9dfe82e1bc28e1ec9b68a9105d3b 583 SUPERFAMILY SSF90123 7 317 1.06E-72 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 ALX04_RS08740 0d9c9dfe82e1bc28e1ec9b68a9105d3b 583 Pfam PF00664 ABC transporter transmembrane region 20 291 5.1E-44 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 ALX04_RS08740 0d9c9dfe82e1bc28e1ec9b68a9105d3b 583 Pfam PF00005 ABC transporter 353 501 1.9E-33 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 ALX04_RS14190 d328145030eb7804793a1ce272e08a53 341 SUPERFAMILY SSF103481 192 306 1.96E-12 T 28-03-2018 ALX04_RS14190 d328145030eb7804793a1ce272e08a53 341 Pfam PF00892 EamA-like transporter family 147 302 4.4E-15 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 ALX04_RS14190 d328145030eb7804793a1ce272e08a53 341 Pfam PF00892 EamA-like transporter family 3 138 1.1E-23 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 ALX04_RS14190 d328145030eb7804793a1ce272e08a53 341 SUPERFAMILY SSF103481 37 140 5.23E-16 T 28-03-2018 ALX04_RS04440 a60dca7f6a98251c21ca1dc04700227c 148 Hamap MF_00518 D-aminoacyl-tRNA deacylase [dtd]. 1 145 33.963 T 28-03-2018 IPR003732 D-aminoacyl-tRNA deacylase DTD GO:0002161|GO:0005737|GO:0051499 ALX04_RS04440 a60dca7f6a98251c21ca1dc04700227c 148 SUPERFAMILY SSF69500 1 144 4.58E-55 T 28-03-2018 IPR023509 D-Tyr tRNAtyr deacylase-like domain ALX04_RS04440 a60dca7f6a98251c21ca1dc04700227c 148 Pfam PF02580 D-Tyr-tRNA(Tyr) deacylase 2 144 6.6E-53 T 28-03-2018 IPR003732 D-aminoacyl-tRNA deacylase DTD GO:0002161|GO:0005737|GO:0051499 ALX04_RS04440 a60dca7f6a98251c21ca1dc04700227c 148 Gene3D G3DSA:3.50.80.10 1 145 1.0E-54 T 28-03-2018 IPR023509 D-Tyr tRNAtyr deacylase-like domain ALX04_RS04440 a60dca7f6a98251c21ca1dc04700227c 148 TIGRFAM TIGR00256 TIGR00256: D-tyrosyl-tRNA(Tyr) deacylase 1 145 4.3E-56 T 28-03-2018 IPR003732 D-aminoacyl-tRNA deacylase DTD GO:0002161|GO:0005737|GO:0051499 ALX04_RS04535 467b37c6bc216ebda88fa1068251fb76 236 Gene3D G3DSA:3.30.1330.80 3 95 8.7E-32 T 28-03-2018 ALX04_RS04535 467b37c6bc216ebda88fa1068251fb76 236 TIGRFAM TIGR01252 acetolac_decarb: alpha-acetolactate decarboxylase 4 235 7.6E-76 T 28-03-2018 IPR005128 Alpha-acetolactate decarboxylase GO:0045151|GO:0047605 KEGG: 00650+4.1.1.5|KEGG: 00660+4.1.1.5|MetaCyc: PWY-5939 ALX04_RS04535 467b37c6bc216ebda88fa1068251fb76 236 PIRSF PIRSF001332 1 236 7.5E-90 T 28-03-2018 IPR005128 Alpha-acetolactate decarboxylase GO:0045151|GO:0047605 KEGG: 00650+4.1.1.5|KEGG: 00660+4.1.1.5|MetaCyc: PWY-5939 ALX04_RS04535 467b37c6bc216ebda88fa1068251fb76 236 SUPERFAMILY SSF117856 5 235 4.19E-78 T 28-03-2018 ALX04_RS04535 467b37c6bc216ebda88fa1068251fb76 236 Pfam PF03306 Alpha-acetolactate decarboxylase 6 223 6.8E-77 T 28-03-2018 IPR005128 Alpha-acetolactate decarboxylase GO:0045151|GO:0047605 KEGG: 00650+4.1.1.5|KEGG: 00660+4.1.1.5|MetaCyc: PWY-5939 ALX04_RS04535 467b37c6bc216ebda88fa1068251fb76 236 Gene3D G3DSA:3.30.1330.80 96 199 4.7E-38 T 28-03-2018 ALX04_RS15720 f42b299048a7b1e131779d78081b12f2 1092 Gene3D G3DSA:3.40.50.300 250 491 5.4E-21 T 28-03-2018 ALX04_RS15720 f42b299048a7b1e131779d78081b12f2 1092 SMART SM00490 561 639 4.6E-19 T 28-03-2018 IPR001650 Helicase, C-terminal ALX04_RS15720 f42b299048a7b1e131779d78081b12f2 1092 Pfam PF00270 DEAD/DEAH box helicase 297 473 1.7E-15 T 28-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 ALX04_RS15720 f42b299048a7b1e131779d78081b12f2 1092 SMART SM00487 288 503 5.0E-14 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain ALX04_RS15720 f42b299048a7b1e131779d78081b12f2 1092 SUPERFAMILY SSF52540 349 649 7.93E-43 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase ALX04_RS15720 f42b299048a7b1e131779d78081b12f2 1092 Gene3D G3DSA:3.40.50.300 503 1077 8.4E-29 T 28-03-2018 ALX04_RS15720 f42b299048a7b1e131779d78081b12f2 1092 Pfam PF00271 Helicase conserved C-terminal domain 531 638 1.7E-17 T 28-03-2018 IPR001650 Helicase, C-terminal ALX04_RS14560 c4849b031638bdddc52ac6d876a55488 291 TIGRFAM TIGR02136 ptsS_2: phosphate binding protein 25 273 5.9E-83 T 28-03-2018 IPR011862 Phosphate binding protein GO:0006810 ALX04_RS14560 c4849b031638bdddc52ac6d876a55488 291 SUPERFAMILY SSF53850 35 282 2.77E-72 T 28-03-2018 ALX04_RS14560 c4849b031638bdddc52ac6d876a55488 291 Gene3D G3DSA:3.40.190.10 167 288 1.3E-13 T 28-03-2018 ALX04_RS14560 c4849b031638bdddc52ac6d876a55488 291 Gene3D G3DSA:3.40.190.10 30 166 4.7E-33 T 28-03-2018 ALX04_RS14560 c4849b031638bdddc52ac6d876a55488 291 Pfam PF12849 PBP superfamily domain 29 258 3.3E-36 T 28-03-2018 IPR024370 PBP domain ALX04_RS02995 b54e6847b770f7cc7b2260fa43a85799 377 Gene3D G3DSA:3.40.630.10 3 375 6.9E-55 T 28-03-2018 ALX04_RS02995 b54e6847b770f7cc7b2260fa43a85799 377 SUPERFAMILY SSF55031 177 284 2.09E-25 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain ALX04_RS02995 b54e6847b770f7cc7b2260fa43a85799 377 PIRSF PIRSF005962 1 374 1.3E-110 T 28-03-2018 IPR017439 Amidohydrolase GO:0016787 ALX04_RS02995 b54e6847b770f7cc7b2260fa43a85799 377 Pfam PF07687 Peptidase dimerisation domain 179 271 1.1E-8 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain ALX04_RS02995 b54e6847b770f7cc7b2260fa43a85799 377 Pfam PF01546 Peptidase family M20/M25/M40 66 367 5.0E-29 T 28-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 ALX04_RS02995 b54e6847b770f7cc7b2260fa43a85799 377 SUPERFAMILY SSF53187 5 190 8.08E-73 T 28-03-2018 ALX04_RS02995 b54e6847b770f7cc7b2260fa43a85799 377 SUPERFAMILY SSF53187 291 372 8.08E-73 T 28-03-2018 ALX04_RS02995 b54e6847b770f7cc7b2260fa43a85799 377 TIGRFAM TIGR01891 amidohydrolases: amidohydrolase 10 359 2.3E-102 T 28-03-2018 IPR017439 Amidohydrolase GO:0016787 ALX04_RS09420 73bedecf530967b05e825d375bd8422d 89 SUPERFAMILY SSF49503 7 87 2.33E-10 T 28-03-2018 IPR008972 Cupredoxin ALX04_RS09420 73bedecf530967b05e825d375bd8422d 89 Pfam PF13473 Cupredoxin-like domain 3 88 3.9E-18 T 28-03-2018 IPR028096 EfeO-type cupredoxin-like domain ALX04_RS09420 73bedecf530967b05e825d375bd8422d 89 Gene3D G3DSA:2.60.40.420 1 89 4.8E-9 T 28-03-2018 IPR008972 Cupredoxin ALX04_RS06135 7c23a065c7476d88e1749e1507de8004 450 SUPERFAMILY SSF53633 2 288 1.06E-62 T 28-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase ALX04_RS06135 7c23a065c7476d88e1749e1507de8004 450 PIRSF PIRSF000726 1 450 5.9E-69 T 28-03-2018 IPR005260 Aspartate kinase, monofunctional class GO:0004072|GO:0009089 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 ALX04_RS06135 7c23a065c7476d88e1749e1507de8004 450 Gene3D G3DSA:3.30.70.260 370 450 4.8E-18 T 28-03-2018 ALX04_RS06135 7c23a065c7476d88e1749e1507de8004 450 SUPERFAMILY SSF55021 376 449 3.93E-20 T 28-03-2018 ALX04_RS06135 7c23a065c7476d88e1749e1507de8004 450 SUPERFAMILY SSF55021 298 362 5.73E-8 T 28-03-2018 ALX04_RS06135 7c23a065c7476d88e1749e1507de8004 450 Pfam PF00696 Amino acid kinase family 2 276 6.2E-41 T 28-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase ALX04_RS06135 7c23a065c7476d88e1749e1507de8004 450 ProSitePatterns PS00324 Aspartokinase signature. 3 11 - T 28-03-2018 IPR018042 Aspartate kinase, conserved site GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 ALX04_RS06135 7c23a065c7476d88e1749e1507de8004 450 Gene3D G3DSA:3.30.70.260 282 369 4.3E-15 T 28-03-2018 ALX04_RS06135 7c23a065c7476d88e1749e1507de8004 450 Gene3D G3DSA:3.40.1160.10 1 281 1.8E-51 T 28-03-2018 ALX04_RS06135 7c23a065c7476d88e1749e1507de8004 450 TIGRFAM TIGR00657 asp_kinases: aspartate kinase 3 449 1.1E-73 T 28-03-2018 IPR001341 Aspartate kinase domain GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 ALX04_RS11490 b30bf370dca5731039be2cbf6ff547b1 264 Gene3D G3DSA:3.90.850.10 1 264 4.8E-20 T 28-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 ALX04_RS11490 b30bf370dca5731039be2cbf6ff547b1 264 SUPERFAMILY SSF56529 4 260 6.26E-43 T 28-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 ALX04_RS03355 87ad78b4c6fd516e5fa6271fa608191f 355 Pfam PF00005 ABC transporter 26 173 1.3E-34 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 ALX04_RS03355 87ad78b4c6fd516e5fa6271fa608191f 355 SMART SM00930 270 345 3.3E-20 T 28-03-2018 IPR018449 NIL domain ALX04_RS03355 87ad78b4c6fd516e5fa6271fa608191f 355 SMART SM00382 34 229 2.2E-12 T 28-03-2018 IPR003593 AAA+ ATPase domain ALX04_RS03355 87ad78b4c6fd516e5fa6271fa608191f 355 SUPERFAMILY SSF52540 5 243 2.48E-80 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase ALX04_RS03355 87ad78b4c6fd516e5fa6271fa608191f 355 Gene3D G3DSA:3.40.50.300 2 270 8.1E-73 T 28-03-2018 ALX04_RS03355 87ad78b4c6fd516e5fa6271fa608191f 355 Gene3D G3DSA:3.30.70.260 271 347 1.0E-16 T 28-03-2018 ALX04_RS03355 87ad78b4c6fd516e5fa6271fa608191f 355 SUPERFAMILY SSF55021 256 346 1.83E-16 T 28-03-2018 ALX04_RS03355 87ad78b4c6fd516e5fa6271fa608191f 355 ProSitePatterns PS00211 ABC transporters family signature. 145 159 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 ALX04_RS03355 87ad78b4c6fd516e5fa6271fa608191f 355 Pfam PF09383 NIL domain 273 342 1.2E-13 T 28-03-2018 IPR018449 NIL domain ALX04_RS07845 4b55572611a88c28620d47c5a64f0736 529 Gene3D G3DSA:3.40.1390.20 11 143 0.0053 T 28-03-2018 IPR028979 HPr(Ser) kinase/phosphorylase, N-terminal domain-like ALX04_RS07845 4b55572611a88c28620d47c5a64f0736 529 Pfam PF13556 PucR C-terminal helix-turn-helix domain 463 520 1.8E-16 T 28-03-2018 IPR025736 PucR C-terminal helix-turn-helix domain ALX04_RS07845 4b55572611a88c28620d47c5a64f0736 529 Gene3D G3DSA:1.10.10.60 439 500 3.4E-6 T 28-03-2018 ALX04_RS07845 4b55572611a88c28620d47c5a64f0736 529 Pfam PF07905 Purine catabolism regulatory protein-like family 6 122 7.5E-26 T 28-03-2018 IPR012914 Purine catabolism PurC-like domain ALX04_RS14530 5832edd8d0627829deee2a838897e10a 188 Hamap MF_00839 Ribosome hibernation promoting factor [hpf]. 2 185 24.85 T 28-03-2018 IPR034694 Ribosome hibernation promoting factor, long/plastid ALX04_RS14530 5832edd8d0627829deee2a838897e10a 188 SUPERFAMILY SSF69754 3 108 1.47E-33 T 28-03-2018 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 ALX04_RS14530 5832edd8d0627829deee2a838897e10a 188 TIGRFAM TIGR00741 yfiA: ribosomal subunit interface protein 3 103 8.8E-30 T 28-03-2018 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 ALX04_RS14530 5832edd8d0627829deee2a838897e10a 188 Pfam PF16321 Sigma 54 modulation/S30EA ribosomal protein C terminus 128 181 6.1E-27 T 28-03-2018 IPR032528 Sigma 54 modulation/S30EA ribosomal protein, C-terminal ALX04_RS14530 5832edd8d0627829deee2a838897e10a 188 Gene3D G3DSA:3.30.160.100 1 103 1.7E-31 T 28-03-2018 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 ALX04_RS14530 5832edd8d0627829deee2a838897e10a 188 Pfam PF02482 Sigma 54 modulation protein / S30EA ribosomal protein 5 96 6.2E-29 T 28-03-2018 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 ALX04_RS11430 67b3d638ff3ab63931ebf73466691620 183 PIRSF PIRSF038321 1 181 4.4E-85 T 28-03-2018 IPR004699 Phosphotransferase system, enzyme II sorbitol-specific factor GO:0009401|GO:0016021 ALX04_RS11430 67b3d638ff3ab63931ebf73466691620 183 Pfam PF03608 PTS system enzyme II sorbitol-specific factor 5 170 2.1E-76 T 28-03-2018 IPR004699 Phosphotransferase system, enzyme II sorbitol-specific factor GO:0009401|GO:0016021 ALX04_RS11430 67b3d638ff3ab63931ebf73466691620 183 TIGRFAM TIGR00821 EII-GUT: PTS system, glucitol/sorbitol-specific, IIC component 2 179 8.6E-80 T 28-03-2018 IPR004699 Phosphotransferase system, enzyme II sorbitol-specific factor GO:0009401|GO:0016021 ALX04_RS02535 6bbb607ecab0ac149340516492b1f057 209 SUPERFAMILY SSF52540 6 201 3.28E-50 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase ALX04_RS02535 6bbb607ecab0ac149340516492b1f057 209 Pfam PF00485 Phosphoribulokinase / Uridine kinase family 11 196 9.9E-46 T 28-03-2018 IPR006083 Phosphoribulokinase/uridine kinase GO:0005524|GO:0008152|GO:0016301 Reactome: R-HSA-73614 ALX04_RS02535 6bbb607ecab0ac149340516492b1f057 209 Gene3D G3DSA:3.40.50.300 5 209 3.4E-61 T 28-03-2018 ALX04_RS02535 6bbb607ecab0ac149340516492b1f057 209 TIGRFAM TIGR00235 udk: uridine kinase 6 208 4.1E-89 T 28-03-2018 IPR000764 Uridine kinase-like KEGG: 00240+2.7.1.48|KEGG: 00983+2.7.1.48|MetaCyc: PWY-7193|Reactome: R-HSA-73614 ALX04_RS02535 6bbb607ecab0ac149340516492b1f057 209 Hamap MF_00551 Uridine kinase [udk]. 6 209 39.493 T 28-03-2018 IPR026008 Uridine kinase GO:0004849|GO:0005524|GO:0016773 KEGG: 00240+2.7.1.48|KEGG: 00983+2.7.1.48|MetaCyc: PWY-7193 ALX04_RS02535 6bbb607ecab0ac149340516492b1f057 209 PRINTS PR00988 Uridine kinase signature 9 26 1.5E-36 T 28-03-2018 ALX04_RS02535 6bbb607ecab0ac149340516492b1f057 209 PRINTS PR00988 Uridine kinase signature 154 165 1.5E-36 T 28-03-2018 ALX04_RS02535 6bbb607ecab0ac149340516492b1f057 209 PRINTS PR00988 Uridine kinase signature 84 99 1.5E-36 T 28-03-2018 ALX04_RS02535 6bbb607ecab0ac149340516492b1f057 209 PRINTS PR00988 Uridine kinase signature 140 150 1.5E-36 T 28-03-2018 ALX04_RS02535 6bbb607ecab0ac149340516492b1f057 209 PRINTS PR00988 Uridine kinase signature 176 189 1.5E-36 T 28-03-2018 ALX04_RS02535 6bbb607ecab0ac149340516492b1f057 209 PRINTS PR00988 Uridine kinase signature 39 50 1.5E-36 T 28-03-2018 ALX04_RS15855 bb565fcc6760b2d8bdfb994a13311a3a 341 Pfam PF13936 Helix-turn-helix domain 15 57 1.0E-15 T 28-03-2018 IPR025246 Transposase IS30-like HTH domain ALX04_RS15855 bb565fcc6760b2d8bdfb994a13311a3a 341 SUPERFAMILY SSF53098 189 339 4.43E-26 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 ALX04_RS15855 bb565fcc6760b2d8bdfb994a13311a3a 341 SUPERFAMILY SSF46689 8 131 1.4E-5 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 ALX04_RS15855 bb565fcc6760b2d8bdfb994a13311a3a 341 Gene3D G3DSA:1.10.10.10 86 161 0.039 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS15855 bb565fcc6760b2d8bdfb994a13311a3a 341 Gene3D G3DSA:3.30.420.10 162 341 1.5E-20 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 ALX04_RS15855 bb565fcc6760b2d8bdfb994a13311a3a 341 ProSitePatterns PS01043 Transposases, IS30 family, signature. 281 297 - T 28-03-2018 IPR001598 Transposase, IS30, conserved site GO:0003677|GO:0004803|GO:0006313 ALX04_RS15855 bb565fcc6760b2d8bdfb994a13311a3a 341 Gene3D G3DSA:1.10.10.60 16 61 2.1E-13 T 28-03-2018 ALX04_RS15855 bb565fcc6760b2d8bdfb994a13311a3a 341 Pfam PF00665 Integrase core domain 191 294 8.8E-10 T 28-03-2018 IPR001584 Integrase, catalytic core GO:0015074 ALX04_RS05935 fc931c7e769d4e6c0c01a6685d5b049f 170 Gene3D G3DSA:1.10.10.160 14 92 9.5E-4 T 28-03-2018 ALX04_RS02900 ecd790ae86cf135f7efe568a80c2cc7f 174 Gene3D G3DSA:2.30.30.240 98 167 1.4E-18 T 28-03-2018 ALX04_RS02900 ecd790ae86cf135f7efe568a80c2cc7f 174 Gene3D G3DSA:2.40.30.60 1 96 7.9E-24 T 28-03-2018 IPR002676 RimM protein GO:0006364 ALX04_RS02900 ecd790ae86cf135f7efe568a80c2cc7f 174 Pfam PF05239 PRC-barrel domain 99 172 8.8E-11 T 28-03-2018 IPR027275 PRC-barrel domain ALX04_RS02900 ecd790ae86cf135f7efe568a80c2cc7f 174 SUPERFAMILY SSF50447 2 93 2.01E-19 T 28-03-2018 IPR009000 Translation protein, beta-barrel domain ALX04_RS02900 ecd790ae86cf135f7efe568a80c2cc7f 174 Hamap MF_00014 Ribosome maturation factor RimM [rimM]. 3 172 23.663 T 28-03-2018 IPR011961 16S rRNA processing protein RimM GO:0005840|GO:0006364|GO:0043022 ALX04_RS02900 ecd790ae86cf135f7efe568a80c2cc7f 174 Pfam PF01782 RimM N-terminal domain 6 91 7.7E-23 T 28-03-2018 IPR002676 RimM protein GO:0006364 ALX04_RS02900 ecd790ae86cf135f7efe568a80c2cc7f 174 SUPERFAMILY SSF50346 101 172 5.1E-19 T 28-03-2018 IPR011033 PRC-barrel-like ALX04_RS02900 ecd790ae86cf135f7efe568a80c2cc7f 174 TIGRFAM TIGR02273 16S_RimM: 16S rRNA processing protein RimM 4 172 4.8E-48 T 28-03-2018 IPR011961 16S rRNA processing protein RimM GO:0005840|GO:0006364|GO:0043022 ALX04_RS12410 0d576bbc61b7cdc3c9868bb82584c98c 998 Pfam PF05738 Cna protein B-type domain 611 695 1.0E-15 T 28-03-2018 IPR008454 Collagen-binding surface protein Cna-like, B-type domain ALX04_RS12410 0d576bbc61b7cdc3c9868bb82584c98c 998 SUPERFAMILY SSF49478 608 692 3.43E-20 T 28-03-2018 ALX04_RS12410 0d576bbc61b7cdc3c9868bb82584c98c 998 SUPERFAMILY SSF49478 709 768 1.92E-7 T 28-03-2018 ALX04_RS12410 0d576bbc61b7cdc3c9868bb82584c98c 998 SUPERFAMILY SSF49478 520 583 5.1E-7 T 28-03-2018 ALX04_RS12410 0d576bbc61b7cdc3c9868bb82584c98c 998 Gene3D G3DSA:2.60.40.1140 607 703 3.1E-21 T 28-03-2018 ALX04_RS12410 0d576bbc61b7cdc3c9868bb82584c98c 998 Gene3D G3DSA:2.60.40.1280 203 348 2.6E-19 T 28-03-2018 IPR011252 Fibrogen-binding domain 1 GO:0005618|GO:0007155 ALX04_RS12410 0d576bbc61b7cdc3c9868bb82584c98c 998 SUPERFAMILY SSF49401 216 363 4.72E-18 T 28-03-2018 IPR008966 Adhesion domain ALX04_RS12410 0d576bbc61b7cdc3c9868bb82584c98c 998 Gene3D G3DSA:2.60.40.10 704 793 1.4E-20 T 28-03-2018 IPR013783 Immunoglobulin-like fold ALX04_RS12410 0d576bbc61b7cdc3c9868bb82584c98c 998 Gene3D G3DSA:2.60.40.10 506 606 1.4E-22 T 28-03-2018 IPR013783 Immunoglobulin-like fold ALX04_RS06990 e7e101474a22a6f2c1d3fefab1811249 161 SUPERFAMILY SSF46785 14 151 4.79E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS06990 e7e101474a22a6f2c1d3fefab1811249 161 Pfam PF12802 MarR family 43 102 4.0E-8 T 28-03-2018 ALX04_RS06990 e7e101474a22a6f2c1d3fefab1811249 161 SMART SM00347 37 142 1.7E-9 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 ALX04_RS06990 e7e101474a22a6f2c1d3fefab1811249 161 Gene3D G3DSA:1.10.10.10 1 161 2.5E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS06990 e7e101474a22a6f2c1d3fefab1811249 161 ProSitePatterns PS01117 MarR-type HTH domain signature. 77 112 - T 28-03-2018 IPR023187 Transcriptional regulator MarR-type, conserved site ALX04_RS02165 3fcf6722f4ae23df6054d4cda128d71c 438 Gene3D G3DSA:3.50.50.60 95 231 6.2E-26 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ALX04_RS02165 3fcf6722f4ae23df6054d4cda128d71c 438 SUPERFAMILY SSF55424 310 432 2.41E-22 T 28-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 ALX04_RS02165 3fcf6722f4ae23df6054d4cda128d71c 438 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 323 419 1.0E-8 T 28-03-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 ALX04_RS02165 3fcf6722f4ae23df6054d4cda128d71c 438 Gene3D G3DSA:3.30.390.30 313 438 5.9E-15 T 28-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 ALX04_RS02165 3fcf6722f4ae23df6054d4cda128d71c 438 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 3 293 6.5E-49 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ALX04_RS02165 3fcf6722f4ae23df6054d4cda128d71c 438 SUPERFAMILY SSF51905 3 301 2.11E-35 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ALX04_RS02165 3fcf6722f4ae23df6054d4cda128d71c 438 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 224 245 1.8E-10 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 ALX04_RS02165 3fcf6722f4ae23df6054d4cda128d71c 438 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 258 276 1.8E-10 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 ALX04_RS02165 3fcf6722f4ae23df6054d4cda128d71c 438 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 3 25 1.8E-10 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 ALX04_RS02165 3fcf6722f4ae23df6054d4cda128d71c 438 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 92 100 1.8E-10 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 ALX04_RS02165 3fcf6722f4ae23df6054d4cda128d71c 438 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 134 158 1.8E-10 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 ALX04_RS02165 3fcf6722f4ae23df6054d4cda128d71c 438 Gene3D G3DSA:3.50.50.60 1 94 5.8E-7 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ALX04_RS02165 3fcf6722f4ae23df6054d4cda128d71c 438 Gene3D G3DSA:3.50.50.60 232 305 7.9E-8 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ALX04_RS02165 3fcf6722f4ae23df6054d4cda128d71c 438 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 222 238 2.7E-27 T 28-03-2018 ALX04_RS02165 3fcf6722f4ae23df6054d4cda128d71c 438 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 91 109 2.7E-27 T 28-03-2018 ALX04_RS02165 3fcf6722f4ae23df6054d4cda128d71c 438 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 248 270 2.7E-27 T 28-03-2018 ALX04_RS02165 3fcf6722f4ae23df6054d4cda128d71c 438 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 4 23 2.7E-27 T 28-03-2018 ALX04_RS02165 3fcf6722f4ae23df6054d4cda128d71c 438 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 138 156 2.7E-27 T 28-03-2018 ALX04_RS07090 498b5069f0bcf3e2f70036b5a2c5d318 507 SMART SM00304 216 268 2.7E-11 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 ALX04_RS07090 498b5069f0bcf3e2f70036b5a2c5d318 507 Pfam PF00672 HAMP domain 216 264 8.1E-11 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 ALX04_RS07090 498b5069f0bcf3e2f70036b5a2c5d318 507 SMART SM00388 276 342 2.7E-17 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 ALX04_RS07090 498b5069f0bcf3e2f70036b5a2c5d318 507 SUPERFAMILY SSF47384 260 343 6.28E-17 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 ALX04_RS07090 498b5069f0bcf3e2f70036b5a2c5d318 507 SUPERFAMILY SSF158472 216 265 1.57E-9 T 28-03-2018 ALX04_RS07090 498b5069f0bcf3e2f70036b5a2c5d318 507 PRINTS PR00344 Bacterial sensor protein C-terminal signature 441 451 2.6E-12 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 ALX04_RS07090 498b5069f0bcf3e2f70036b5a2c5d318 507 PRINTS PR00344 Bacterial sensor protein C-terminal signature 423 437 2.6E-12 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 ALX04_RS07090 498b5069f0bcf3e2f70036b5a2c5d318 507 PRINTS PR00344 Bacterial sensor protein C-terminal signature 459 477 2.6E-12 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 ALX04_RS07090 498b5069f0bcf3e2f70036b5a2c5d318 507 PRINTS PR00344 Bacterial sensor protein C-terminal signature 483 496 2.6E-12 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 ALX04_RS07090 498b5069f0bcf3e2f70036b5a2c5d318 507 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 388 498 2.8E-24 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain ALX04_RS07090 498b5069f0bcf3e2f70036b5a2c5d318 507 Pfam PF00512 His Kinase A (phospho-acceptor) domain 277 342 6.5E-13 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 ALX04_RS07090 498b5069f0bcf3e2f70036b5a2c5d318 507 Gene3D G3DSA:3.30.565.10 346 503 1.9E-40 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain ALX04_RS07090 498b5069f0bcf3e2f70036b5a2c5d318 507 Gene3D G3DSA:1.10.287.130 266 338 6.6E-15 T 28-03-2018 ALX04_RS07090 498b5069f0bcf3e2f70036b5a2c5d318 507 SUPERFAMILY SSF55874 331 496 6.29E-41 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain ALX04_RS07090 498b5069f0bcf3e2f70036b5a2c5d318 507 SMART SM00387 387 499 1.4E-34 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain ALX04_RS09295 e8238b0b3f9e1564a2629c3a7533e89f 303 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 62 4.3E-17 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 ALX04_RS09295 e8238b0b3f9e1564a2629c3a7533e89f 303 SUPERFAMILY SSF53850 104 205 2.35E-6 T 28-03-2018 ALX04_RS09295 e8238b0b3f9e1564a2629c3a7533e89f 303 SUPERFAMILY SSF46785 2 86 8.16E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS09295 e8238b0b3f9e1564a2629c3a7533e89f 303 Gene3D G3DSA:3.40.190.10 85 204 6.0E-7 T 28-03-2018 ALX04_RS09295 e8238b0b3f9e1564a2629c3a7533e89f 303 Gene3D G3DSA:1.10.10.10 1 84 3.1E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS12530 0b8482c98708a35d506ec5f3d5c9aa83 67 Gene3D G3DSA:1.10.10.60 1 27 8.1E-11 T 28-03-2018 ALX04_RS12530 0b8482c98708a35d506ec5f3d5c9aa83 67 SUPERFAMILY SSF47413 3 65 1.1E-17 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 ALX04_RS12530 0b8482c98708a35d506ec5f3d5c9aa83 67 Gene3D G3DSA:3.30.1190.10 28 66 1.4E-11 T 28-03-2018 ALX04_RS12530 0b8482c98708a35d506ec5f3d5c9aa83 67 SMART SM00530 6 61 7.2E-13 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 ALX04_RS12530 0b8482c98708a35d506ec5f3d5c9aa83 67 Pfam PF01381 Helix-turn-helix 7 59 1.5E-15 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 ALX04_RS09135 e4d2986068b70ee5aa7efec55c098551 223 SUPERFAMILY SSF47413 1 65 4.56E-18 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 ALX04_RS09135 e4d2986068b70ee5aa7efec55c098551 223 Pfam PF01381 Helix-turn-helix 7 60 2.8E-14 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 ALX04_RS09135 e4d2986068b70ee5aa7efec55c098551 223 Gene3D G3DSA:1.10.10.60 1 28 4.4E-14 T 28-03-2018 ALX04_RS09135 e4d2986068b70ee5aa7efec55c098551 223 Gene3D G3DSA:1.10.260.40 29 94 1.7E-4 T 28-03-2018 ALX04_RS09135 e4d2986068b70ee5aa7efec55c098551 223 SMART SM00530 6 61 7.4E-14 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 ALX04_RS13325 1e2b522bd753a820a525d617145bf6db 271 SUPERFAMILY SSF56784 1 267 3.55E-70 T 28-03-2018 IPR023214 HAD-like domain ALX04_RS13325 1e2b522bd753a820a525d617145bf6db 271 Gene3D G3DSA:3.40.50.1000 1 271 5.4E-48 T 28-03-2018 IPR023214 HAD-like domain ALX04_RS13325 1e2b522bd753a820a525d617145bf6db 271 Pfam PF08282 haloacid dehalogenase-like hydrolase 6 264 3.0E-64 T 28-03-2018 IPR023214 HAD-like domain ALX04_RS13325 1e2b522bd753a820a525d617145bf6db 271 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 5 88 9.1E-15 T 28-03-2018 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 ALX04_RS13325 1e2b522bd753a820a525d617145bf6db 271 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 169 237 1.0E-12 T 28-03-2018 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 ALX04_RS13325 1e2b522bd753a820a525d617145bf6db 271 TIGRFAM TIGR00099 Cof-subfamily: Cof-like hydrolase 5 264 2.9E-59 T 28-03-2018 IPR000150 Cof family GO:0016787 ALX04_RS14100 68e394486bf819e844b0ac8caa42b31c 428 SUPERFAMILY SSF55021 347 414 6.11E-8 T 28-03-2018 ALX04_RS14100 68e394486bf819e844b0ac8caa42b31c 428 Gene3D G3DSA:3.40.50.720 1 157 3.9E-33 T 28-03-2018 ALX04_RS14100 68e394486bf819e844b0ac8caa42b31c 428 SUPERFAMILY SSF51735 1 158 2.34E-35 T 28-03-2018 IPR016040 NAD(P)-binding domain ALX04_RS14100 68e394486bf819e844b0ac8caa42b31c 428 Gene3D G3DSA:3.30.360.10 158 298 2.0E-51 T 28-03-2018 ALX04_RS14100 68e394486bf819e844b0ac8caa42b31c 428 PIRSF PIRSF000098 1 428 1.7E-169 T 28-03-2018 IPR016204 Homoserine dehydrogenase GO:0004412|GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 ALX04_RS14100 68e394486bf819e844b0ac8caa42b31c 428 SUPERFAMILY SSF55347 137 302 9.15E-52 T 28-03-2018 ALX04_RS14100 68e394486bf819e844b0ac8caa42b31c 428 Pfam PF03447 Homoserine dehydrogenase, NAD binding domain 10 129 8.2E-24 T 28-03-2018 IPR005106 Aspartate/homoserine dehydrogenase, NAD-binding GO:0016491|GO:0050661|GO:0055114 ALX04_RS14100 68e394486bf819e844b0ac8caa42b31c 428 Gene3D G3DSA:3.30.70.260 346 422 1.5E-8 T 28-03-2018 ALX04_RS14100 68e394486bf819e844b0ac8caa42b31c 428 Pfam PF00742 Homoserine dehydrogenase 137 314 4.0E-63 T 28-03-2018 IPR001342 Homoserine dehydrogenase, catalytic GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 ALX04_RS14100 68e394486bf819e844b0ac8caa42b31c 428 ProSitePatterns PS01042 Homoserine dehydrogenase signature. 183 205 - T 28-03-2018 IPR019811 Homoserine dehydrogenase, conserved site GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 ALX04_RS05420 8856532a4de22fb39e8a97ccc938a2b5 220 SUPERFAMILY SSF116726 130 215 2.62E-14 T 28-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 ALX04_RS05420 8856532a4de22fb39e8a97ccc938a2b5 220 SUPERFAMILY SSF51735 4 134 1.28E-31 T 28-03-2018 IPR016040 NAD(P)-binding domain ALX04_RS05420 8856532a4de22fb39e8a97ccc938a2b5 220 Gene3D G3DSA:3.30.70.1450 138 217 3.4E-12 T 28-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 ALX04_RS05420 8856532a4de22fb39e8a97ccc938a2b5 220 Pfam PF02080 TrkA-C domain 151 216 1.1E-7 T 28-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 ALX04_RS05420 8856532a4de22fb39e8a97ccc938a2b5 220 Gene3D G3DSA:3.40.50.720 1 137 4.4E-21 T 28-03-2018 ALX04_RS05420 8856532a4de22fb39e8a97ccc938a2b5 220 Pfam PF02254 TrkA-N domain 5 120 8.1E-27 T 28-03-2018 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 ALX04_RS16060 1fd2b77feeb832bc5c118e4b54637b50 316 Gene3D G3DSA:1.10.620.20 2 290 3.0E-69 T 28-03-2018 ALX04_RS16060 1fd2b77feeb832bc5c118e4b54637b50 316 Pfam PF00268 Ribonucleotide reductase, small chain 6 270 1.3E-76 T 28-03-2018 IPR000358 Ribonucleotide reductase small subunit family GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 ALX04_RS16060 1fd2b77feeb832bc5c118e4b54637b50 316 TIGRFAM TIGR04171 RNR_1b_NrdF: ribonucleoside-diphosphate reductase, class 1b, beta subunit 3 316 3.4E-129 T 28-03-2018 IPR026494 Ribonucleoside reductase subunit beta, NrdF GO:0005971|GO:0009263 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227 ALX04_RS16060 1fd2b77feeb832bc5c118e4b54637b50 316 SUPERFAMILY SSF47240 3 316 1.3E-84 T 28-03-2018 IPR009078 Ferritin-like superfamily ALX04_RS02750 6cc0e8d9d41d3a4121890161e8623646 564 Gene3D G3DSA:3.40.50.300 262 538 8.3E-19 T 28-03-2018 ALX04_RS02750 6cc0e8d9d41d3a4121890161e8623646 564 Gene3D G3DSA:3.40.50.300 1 252 2.6E-27 T 28-03-2018 ALX04_RS02750 6cc0e8d9d41d3a4121890161e8623646 564 PIRSF PIRSF003128 1 561 7.1E-178 T 28-03-2018 IPR004604 DNA recombination/repair protein RecN GO:0005524|GO:0006281|GO:0006310 ALX04_RS02750 6cc0e8d9d41d3a4121890161e8623646 564 SUPERFAMILY SSF52540 355 519 2.97E-63 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase ALX04_RS02750 6cc0e8d9d41d3a4121890161e8623646 564 SUPERFAMILY SSF52540 2 202 2.97E-63 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase ALX04_RS02750 6cc0e8d9d41d3a4121890161e8623646 564 SUPERFAMILY SSF52540 291 326 2.97E-63 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase ALX04_RS02750 6cc0e8d9d41d3a4121890161e8623646 564 TIGRFAM TIGR00634 recN: DNA repair protein RecN 1 556 1.8E-179 T 28-03-2018 IPR004604 DNA recombination/repair protein RecN GO:0005524|GO:0006281|GO:0006310 ALX04_RS02750 6cc0e8d9d41d3a4121890161e8623646 564 Pfam PF02463 RecF/RecN/SMC N terminal domain 2 511 8.6E-15 T 28-03-2018 IPR003395 RecF/RecN/SMC, N-terminal ALX04_RS09680 ab4ac5e3e8a838c2dac7d2f769d58f0d 86 Pfam PF08765 Mor transcription activator family 9 85 1.2E-6 T 28-03-2018 IPR014875 Mor transcription activator ALX04_RS09680 ab4ac5e3e8a838c2dac7d2f769d58f0d 86 Gene3D G3DSA:1.10.10.60 45 86 1.6E-7 T 28-03-2018 ALX04_RS09680 ab4ac5e3e8a838c2dac7d2f769d58f0d 86 SUPERFAMILY SSF46689 3 85 6.09E-11 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 ALX04_RS03670 d4d395e7263f7e772cdbfeab129c00da 233 Pfam PF01128 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase 4 230 1.0E-43 T 28-03-2018 IPR034683 Cytidylyltransferase IspD/TarI GO:0070567 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 ALX04_RS03670 d4d395e7263f7e772cdbfeab129c00da 233 ProSitePatterns PS01295 4-diphosphocytidyl-2C-methyl-D-erythritol synthase signature. 106 113 - T 28-03-2018 IPR018294 4-diphosphocytidyl-2C-methyl-D-erythritol synthase, conserved site GO:0003824|GO:0008299 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 ALX04_RS03670 d4d395e7263f7e772cdbfeab129c00da 233 Gene3D G3DSA:3.90.550.10 1 233 3.8E-41 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases ALX04_RS03670 d4d395e7263f7e772cdbfeab129c00da 233 SUPERFAMILY SSF53448 1 229 2.48E-50 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases ALX04_RS03670 d4d395e7263f7e772cdbfeab129c00da 233 Hamap MF_02068 Ribitol-5-phosphate cytidylyltransferase [tarI]. 1 232 46.656 T 28-03-2018 IPR034709 Ribitol-5-phosphate cytidylyltransferase GO:0047349 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 ALX04_RS07570 5e06c753be4854ef81b54d87975c2acf 373 PIRSF PIRSF001434 1 372 1.0E-117 T 28-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 ALX04_RS07570 5e06c753be4854ef81b54d87975c2acf 373 ProSitePatterns PS00868 Cys/Met metabolism enzymes pyridoxal-phosphate attachment site. 195 209 - T 28-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 ALX04_RS07570 5e06c753be4854ef81b54d87975c2acf 373 Gene3D G3DSA:3.40.640.10 8 252 2.0E-47 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 ALX04_RS07570 5e06c753be4854ef81b54d87975c2acf 373 Gene3D G3DSA:3.90.1150.10 253 284 5.4E-5 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 ALX04_RS07570 5e06c753be4854ef81b54d87975c2acf 373 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 11 368 2.0E-117 T 28-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 ALX04_RS07570 5e06c753be4854ef81b54d87975c2acf 373 SUPERFAMILY SSF53383 29 368 3.99E-93 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase ALX04_RS07570 5e06c753be4854ef81b54d87975c2acf 373 Gene3D G3DSA:3.90.1150.10 285 373 3.4E-26 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 ALX04_RS04115 118d4d594c87962d5bbff71c180a3e1d 201 Pfam PF12535 Hydrolase of X-linked nucleoside diphosphate N terminal 5 55 3.6E-11 T 28-03-2018 ALX04_RS04115 118d4d594c87962d5bbff71c180a3e1d 201 Pfam PF00293 NUDIX domain 74 177 1.9E-11 T 28-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 ALX04_RS04115 118d4d594c87962d5bbff71c180a3e1d 201 Gene3D G3DSA:3.90.79.10 57 200 6.0E-21 T 28-03-2018 ALX04_RS04115 118d4d594c87962d5bbff71c180a3e1d 201 SUPERFAMILY SSF55811 62 193 4.74E-26 T 28-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 ALX04_RS08080 a23e8aa2ee8dc9c79c6ac7a3586c4aec 200 SMART SM01266 7 59 3.3E-9 T 28-03-2018 IPR024688 Maltose/galactoside acetyltransferase GO:0016407 ALX04_RS08080 a23e8aa2ee8dc9c79c6ac7a3586c4aec 200 SUPERFAMILY SSF51161 7 186 5.82E-45 T 28-03-2018 IPR011004 Trimeric LpxA-like ALX04_RS08080 a23e8aa2ee8dc9c79c6ac7a3586c4aec 200 Pfam PF12464 Maltose acetyltransferase 10 58 2.1E-7 T 28-03-2018 IPR024688 Maltose/galactoside acetyltransferase GO:0016407 ALX04_RS08080 a23e8aa2ee8dc9c79c6ac7a3586c4aec 200 Gene3D G3DSA:2.160.10.10 2 192 2.9E-44 T 28-03-2018 ALX04_RS08080 a23e8aa2ee8dc9c79c6ac7a3586c4aec 200 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 131 165 4.9E-10 T 28-03-2018 IPR001451 Hexapeptide repeat ALX04_RS08080 a23e8aa2ee8dc9c79c6ac7a3586c4aec 200 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 139 167 - T 28-03-2018 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 ALX04_RS12065 7682cb4aa6c38979d018f23da3f97c1a 156 SUPERFAMILY SSF55811 14 142 9.88E-26 T 28-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 ALX04_RS12065 7682cb4aa6c38979d018f23da3f97c1a 156 Pfam PF00293 NUDIX domain 21 142 1.2E-15 T 28-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 ALX04_RS12065 7682cb4aa6c38979d018f23da3f97c1a 156 PRINTS PR00502 NUDIX hydrolase family signature 58 73 2.3E-5 T 28-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 ALX04_RS12065 7682cb4aa6c38979d018f23da3f97c1a 156 PRINTS PR00502 NUDIX hydrolase family signature 44 58 2.3E-5 T 28-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 ALX04_RS12065 7682cb4aa6c38979d018f23da3f97c1a 156 Gene3D G3DSA:3.90.79.10 1 150 1.2E-21 T 28-03-2018 ALX04_RS12280 9c4944d1eb806520436c7a237b8cd70d 332 Gene3D G3DSA:3.40.50.10440 11 185 1.3E-70 T 28-03-2018 ALX04_RS12280 9c4944d1eb806520436c7a237b8cd70d 332 SUPERFAMILY SSF82549 10 331 3.14E-121 T 28-03-2018 ALX04_RS12280 9c4944d1eb806520436c7a237b8cd70d 332 Gene3D G3DSA:3.30.1180.20 186 332 8.7E-44 T 28-03-2018 ALX04_RS12280 9c4944d1eb806520436c7a237b8cd70d 332 TIGRFAM TIGR02363 dhaK1: dihydroxyacetone kinase, DhaK subunit 1 331 1.8E-161 T 28-03-2018 IPR012736 Dihydroxyacetone kinase DhaK, subunit 1 ALX04_RS12280 9c4944d1eb806520436c7a237b8cd70d 332 Pfam PF02733 Dak1 domain 18 329 1.7E-117 T 28-03-2018 IPR004006 DhaK domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 ALX04_RS10310 584963a2a331ce60e418acf07825456d 195 Gene3D G3DSA:3.90.950.10 1 195 1.2E-40 T 28-03-2018 IPR029001 Inosine triphosphate pyrophosphatase-like ALX04_RS10310 584963a2a331ce60e418acf07825456d 195 Pfam PF01725 Ham1 family 7 192 1.1E-28 T 28-03-2018 IPR002637 Ham1-like protein GO:0009143|GO:0047429 Reactome: R-HSA-74259 ALX04_RS10310 584963a2a331ce60e418acf07825456d 195 SUPERFAMILY SSF52972 3 194 8.37E-45 T 28-03-2018 IPR029001 Inosine triphosphate pyrophosphatase-like ALX04_RS13480 0b1252b63d342db9facef4ef4158e9b8 248 SUPERFAMILY SSF53697 93 241 1.31E-30 T 28-03-2018 ALX04_RS13480 0b1252b63d342db9facef4ef4158e9b8 248 Gene3D G3DSA:3.40.50.10490 99 240 3.5E-22 T 28-03-2018 ALX04_RS13480 0b1252b63d342db9facef4ef4158e9b8 248 Pfam PF01418 Helix-turn-helix domain, rpiR family 11 71 7.4E-10 T 28-03-2018 IPR000281 Helix-turn-helix protein RpiR GO:0003700|GO:0006355 ALX04_RS13480 0b1252b63d342db9facef4ef4158e9b8 248 Pfam PF01380 SIS domain 105 213 4.5E-13 T 28-03-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 ALX04_RS13480 0b1252b63d342db9facef4ef4158e9b8 248 Gene3D G3DSA:1.10.10.10 6 98 4.2E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS13480 0b1252b63d342db9facef4ef4158e9b8 248 SUPERFAMILY SSF46689 9 71 1.15E-15 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 ALX04_RS07290 bb5e00d54fe080629b732ced6c8da724 239 Pfam PF00977 Histidine biosynthesis protein 1 228 2.8E-72 T 28-03-2018 IPR006062 Histidine biosynthesis GO:0000105 ALX04_RS07290 bb5e00d54fe080629b732ced6c8da724 239 TIGRFAM TIGR00007 TIGR00007: 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide isomerase 2 232 6.5E-75 T 28-03-2018 IPR006063 Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase HisA GO:0000105|GO:0003949 KEGG: 00340+5.3.1.16 ALX04_RS07290 bb5e00d54fe080629b732ced6c8da724 239 SUPERFAMILY SSF51366 1 233 5.32E-59 T 28-03-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 ALX04_RS07290 bb5e00d54fe080629b732ced6c8da724 239 Gene3D G3DSA:3.20.20.70 1 238 1.3E-44 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 ALX04_RS07290 bb5e00d54fe080629b732ced6c8da724 239 Hamap MF_01014 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase [hisA]. 1 236 33.603 T 28-03-2018 IPR023016 Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase GO:0000105|GO:0003949 KEGG: 00340+5.3.1.16 ALX04_RS12840 9fac23925b6dd40729328eab18b7d652 464 Gene3D G3DSA:1.10.45.10 424 461 1.3E-9 T 28-03-2018 IPR016171 Vanillyl-alcohol oxidase, C-terminal subdomain 2 ALX04_RS12840 9fac23925b6dd40729328eab18b7d652 464 Gene3D G3DSA:3.30.43.10 5 101 4.9E-13 T 28-03-2018 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 ALX04_RS12840 9fac23925b6dd40729328eab18b7d652 464 Gene3D G3DSA:3.30.465.10 102 247 3.5E-41 T 28-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 ALX04_RS12840 9fac23925b6dd40729328eab18b7d652 464 Pfam PF02913 FAD linked oxidases, C-terminal domain 231 460 3.0E-46 T 28-03-2018 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 ALX04_RS12840 9fac23925b6dd40729328eab18b7d652 464 Pfam PF01565 FAD binding domain 50 187 1.4E-36 T 28-03-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 ALX04_RS12840 9fac23925b6dd40729328eab18b7d652 464 SUPERFAMILY SSF55103 231 463 1.28E-45 T 28-03-2018 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 ALX04_RS12840 9fac23925b6dd40729328eab18b7d652 464 SUPERFAMILY SSF56176 6 225 7.01E-62 T 28-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 ALX04_RS00125 fc9cd50ec17edabcad2812dc91480ca0 109 Pfam PF08951 Enterocin A Immunity 18 64 2.8E-7 T 28-03-2018 IPR015046 Enterocin A Immunity ALX04_RS00125 fc9cd50ec17edabcad2812dc91480ca0 109 SUPERFAMILY SSF109797 13 109 1.54E-28 T 28-03-2018 ALX04_RS00125 fc9cd50ec17edabcad2812dc91480ca0 109 Gene3D G3DSA:1.20.1440.50 15 104 5.3E-18 T 28-03-2018 IPR023130 Ta0600-like domain ALX04_RS11610 637edcc26e3c06d99376db1d2cdd2230 78 TIGRFAM TIGR00165 S18: ribosomal protein bS18 10 76 4.1E-29 T 28-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 ALX04_RS11610 637edcc26e3c06d99376db1d2cdd2230 78 Pfam PF01084 Ribosomal protein S18 22 72 6.4E-28 T 28-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 ALX04_RS11610 637edcc26e3c06d99376db1d2cdd2230 78 SUPERFAMILY SSF46911 4 77 6.28E-28 T 28-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 ALX04_RS11610 637edcc26e3c06d99376db1d2cdd2230 78 Gene3D G3DSA:4.10.640.10 1 78 1.3E-31 T 28-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 ALX04_RS11610 637edcc26e3c06d99376db1d2cdd2230 78 Hamap MF_00270 30S ribosomal protein S18 [rpsR]. 5 77 21.622 T 28-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 ALX04_RS11610 637edcc26e3c06d99376db1d2cdd2230 78 ProSitePatterns PS00057 Ribosomal protein S18 signature. 25 48 - T 28-03-2018 IPR018275 Ribosomal protein S18, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 ALX04_RS11610 637edcc26e3c06d99376db1d2cdd2230 78 PRINTS PR00974 Ribosomal protein S18 family signature 32 42 6.8E-20 T 28-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 ALX04_RS11610 637edcc26e3c06d99376db1d2cdd2230 78 PRINTS PR00974 Ribosomal protein S18 family signature 50 64 6.8E-20 T 28-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 ALX04_RS11610 637edcc26e3c06d99376db1d2cdd2230 78 PRINTS PR00974 Ribosomal protein S18 family signature 64 74 6.8E-20 T 28-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 ALX04_RS11610 637edcc26e3c06d99376db1d2cdd2230 78 PRINTS PR00974 Ribosomal protein S18 family signature 42 49 6.8E-20 T 28-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 ALX04_RS11610 637edcc26e3c06d99376db1d2cdd2230 78 ProDom PD002239 RIBOSOMAL S18 RIBONUCLEOPROTEIN 30S RRNA-BINDING RNA-BINDING CHLOROPLAST PLASTID MITOCHONDRIAL ACETYLATION 24 77 2.0E-24 T 28-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 ALX04_RS08120 7e8f22f4d8bb17565afe84edd3c0382b 169 Pfam PF08279 HTH domain 6 58 1.0E-12 T 28-03-2018 IPR013196 Helix-turn-helix, type 11 ALX04_RS08120 7e8f22f4d8bb17565afe84edd3c0382b 169 SUPERFAMILY SSF46785 1 60 7.18E-10 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS08120 7e8f22f4d8bb17565afe84edd3c0382b 169 ProDom PD469575 TRANSCRIPTION DNA-BINDING REGULATION TRANSCRIPTIONAL REGULATOR REPRESSOR FAMILY BIOTIN REGULATOR 3H 73 166 7.0E-50 T 28-03-2018 IPR004173 3H domain GO:0036094 ALX04_RS08120 7e8f22f4d8bb17565afe84edd3c0382b 169 PIRSF PIRSF037847 1 169 3.4E-60 T 28-03-2018 IPR026043 Transcription repressor NadR ALX04_RS08120 7e8f22f4d8bb17565afe84edd3c0382b 169 SUPERFAMILY SSF75500 65 168 3.79E-34 T 28-03-2018 IPR004173 3H domain GO:0036094 ALX04_RS08120 7e8f22f4d8bb17565afe84edd3c0382b 169 Gene3D G3DSA:1.10.10.10 1 63 9.2E-12 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS08120 7e8f22f4d8bb17565afe84edd3c0382b 169 Pfam PF02829 3H domain 71 166 1.1E-28 T 28-03-2018 IPR004173 3H domain GO:0036094 ALX04_RS08120 7e8f22f4d8bb17565afe84edd3c0382b 169 Gene3D G3DSA:3.30.1340.20 67 167 1.9E-30 T 28-03-2018 IPR004173 3H domain GO:0036094 ALX04_RS00880 c51c834b29486aba9801626a307142c5 487 Gene3D G3DSA:3.90.1300.10 3 483 3.1E-168 T 28-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 ALX04_RS00880 c51c834b29486aba9801626a307142c5 487 TIGRFAM TIGR00132 gatA: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, A subunit 13 475 7.0E-191 T 28-03-2018 IPR004412 Glutamyl-tRNA(Gln) amidotransferase A subunit GO:0006412|GO:0030956|GO:0050567 KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 ALX04_RS00880 c51c834b29486aba9801626a307142c5 487 Pfam PF01425 Amidase 25 462 4.7E-155 T 28-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 ALX04_RS00880 c51c834b29486aba9801626a307142c5 487 Hamap MF_00120 Glutamyl-tRNA(Gln) amidotransferase subunit A [gatA]. 11 475 92.887 T 28-03-2018 IPR004412 Glutamyl-tRNA(Gln) amidotransferase A subunit GO:0006412|GO:0030956|GO:0050567 KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 ALX04_RS00880 c51c834b29486aba9801626a307142c5 487 ProSitePatterns PS00571 Amidases signature. 150 181 - T 28-03-2018 IPR020556 Amidase, conserved site KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921|Reactome: R-HSA-2142753 ALX04_RS00880 c51c834b29486aba9801626a307142c5 487 SUPERFAMILY SSF75304 1 481 6.67E-163 T 28-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 ALX04_RS03165 75d1ee314cba4c7be25599bb1b47bcf3 93 Gene3D G3DSA:3.30.70.100 2 93 1.4E-15 T 28-03-2018 ALX04_RS03165 75d1ee314cba4c7be25599bb1b47bcf3 93 Pfam PF03992 Antibiotic biosynthesis monooxygenase 3 75 4.5E-9 T 28-03-2018 IPR007138 Antibiotic biosynthesis monooxygenase domain ALX04_RS03165 75d1ee314cba4c7be25599bb1b47bcf3 93 SUPERFAMILY SSF54909 1 92 3.38E-21 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel ALX04_RS09090 e80807d7f442da672551882a0c85b9f1 211 SUPERFAMILY SSF55021 145 201 6.7E-5 T 28-03-2018 ALX04_RS09090 e80807d7f442da672551882a0c85b9f1 211 SUPERFAMILY SSF54631 1 132 3.54E-29 T 28-03-2018 ALX04_RS09090 e80807d7f442da672551882a0c85b9f1 211 Pfam PF00571 CBS domain 77 131 1.4E-8 T 28-03-2018 IPR000644 CBS domain ALX04_RS09090 e80807d7f442da672551882a0c85b9f1 211 Pfam PF00571 CBS domain 3 54 1.6E-10 T 28-03-2018 IPR000644 CBS domain ALX04_RS09090 e80807d7f442da672551882a0c85b9f1 211 Gene3D G3DSA:3.10.580.10 1 135 1.9E-27 T 28-03-2018 ALX04_RS09090 e80807d7f442da672551882a0c85b9f1 211 Gene3D G3DSA:3.30.70.260 136 205 2.9E-5 T 28-03-2018 ALX04_RS09090 e80807d7f442da672551882a0c85b9f1 211 SMART SM00116 10 57 6.1E-9 T 28-03-2018 IPR000644 CBS domain ALX04_RS09090 e80807d7f442da672551882a0c85b9f1 211 SMART SM00116 84 131 2.8E-7 T 28-03-2018 IPR000644 CBS domain ALX04_RS11215 8197bc17660e810d558251993d024a25 324 Pfam PF02275 Linear amide C-N hydrolases, choloylglycine hydrolase family 2 312 4.0E-127 T 28-03-2018 IPR029132 Choloylglycine hydrolase/NAAA C-terminal ALX04_RS11215 8197bc17660e810d558251993d024a25 324 SUPERFAMILY SSF56235 2 324 9.26E-106 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal ALX04_RS11215 8197bc17660e810d558251993d024a25 324 Gene3D G3DSA:3.60.60.10 1 314 2.2E-87 T 28-03-2018 ALX04_RS05805 50f48105180aec217c01d33fe5ad9b60 126 Gene3D G3DSA:3.90.79.10 1 120 8.8E-4 T 28-03-2018 ALX04_RS06240 093f92713c97da42f43b0ceb73322790 202 Gene3D G3DSA:1.10.1050.10 1 98 1.4E-37 T 28-03-2018 ALX04_RS06240 093f92713c97da42f43b0ceb73322790 202 Hamap MF_01306_B 30S ribosomal protein S4 [rpsD]. 1 201 35.038 T 28-03-2018 IPR005709 Ribosomal protein S4, bacterial-type GO:0003735|GO:0006412|GO:0015935 ALX04_RS06240 093f92713c97da42f43b0ceb73322790 202 ProSitePatterns PS00632 Ribosomal protein S4 signature. 91 115 - T 28-03-2018 IPR018079 Ribosomal protein S4, conserved site GO:0005622|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6790901|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 ALX04_RS06240 093f92713c97da42f43b0ceb73322790 202 Gene3D G3DSA:3.10.290.10 99 141 6.0E-18 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 ALX04_RS06240 093f92713c97da42f43b0ceb73322790 202 TIGRFAM TIGR01017 rpsD_bact: ribosomal protein uS4 3 201 1.7E-78 T 28-03-2018 IPR005709 Ribosomal protein S4, bacterial-type GO:0003735|GO:0006412|GO:0015935 ALX04_RS06240 093f92713c97da42f43b0ceb73322790 202 SMART SM00363 93 157 2.6E-20 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 ALX04_RS06240 093f92713c97da42f43b0ceb73322790 202 Gene3D G3DSA:1.10.1050.10 142 201 1.0E-12 T 28-03-2018 ALX04_RS06240 093f92713c97da42f43b0ceb73322790 202 Pfam PF00163 Ribosomal protein S4/S9 N-terminal domain 3 92 1.3E-26 T 28-03-2018 IPR001912 Ribosomal protein S4/S9, N-terminal GO:0005622|GO:0019843 Reactome: R-HSA-6790901|Reactome: R-HSA-6791226 ALX04_RS06240 093f92713c97da42f43b0ceb73322790 202 SMART SM01390 3 92 9.3E-43 T 28-03-2018 IPR001912 Ribosomal protein S4/S9, N-terminal GO:0005622|GO:0019843 Reactome: R-HSA-6790901|Reactome: R-HSA-6791226 ALX04_RS06240 093f92713c97da42f43b0ceb73322790 202 SUPERFAMILY SSF55174 3 201 2.36E-67 T 28-03-2018 ALX04_RS06240 093f92713c97da42f43b0ceb73322790 202 Pfam PF01479 S4 domain 93 140 1.1E-20 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 ALX04_RS13555 da3657a45ef7873c4126da33a7ddeb17 314 Pfam PF12697 Alpha/beta hydrolase family 95 297 2.6E-6 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 ALX04_RS13555 da3657a45ef7873c4126da33a7ddeb17 314 SUPERFAMILY SSF53474 57 309 1.05E-38 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold ALX04_RS13555 da3657a45ef7873c4126da33a7ddeb17 314 Gene3D G3DSA:3.40.50.1820 37 312 1.3E-35 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold ALX04_RS14375 4cae72026d4888da5cea2048dc8f21b8 199 Hamap MF_00017 Recombination protein RecR [recR]. 1 199 103.125 T 28-03-2018 IPR000093 DNA recombination protein RecR GO:0003677|GO:0006281|GO:0006310 ALX04_RS14375 4cae72026d4888da5cea2048dc8f21b8 199 Gene3D G3DSA:3.40.1360.10 77 171 1.9E-37 T 28-03-2018 ALX04_RS14375 4cae72026d4888da5cea2048dc8f21b8 199 Pfam PF13662 Toprim domain 80 172 1.5E-24 T 28-03-2018 IPR006171 TOPRIM domain ALX04_RS14375 4cae72026d4888da5cea2048dc8f21b8 199 ProSitePatterns PS01300 RecR protein signature. 57 78 - T 28-03-2018 IPR015967 Recombination protein RecR, conserved site GO:0006281|GO:0006310 ALX04_RS14375 4cae72026d4888da5cea2048dc8f21b8 199 SUPERFAMILY SSF111304 1 199 1.7E-73 T 28-03-2018 IPR023627 Recombination protein RecR ALX04_RS14375 4cae72026d4888da5cea2048dc8f21b8 199 Pfam PF02132 RecR protein 39 78 3.3E-16 T 28-03-2018 IPR023628 Recombination protein RecR, C4-type zinc finger ALX04_RS14375 4cae72026d4888da5cea2048dc8f21b8 199 SMART SM00493 80 166 4.6E-17 T 28-03-2018 IPR006171 TOPRIM domain ALX04_RS14375 4cae72026d4888da5cea2048dc8f21b8 199 TIGRFAM TIGR00615 recR: recombination protein RecR 1 197 4.4E-79 T 28-03-2018 IPR000093 DNA recombination protein RecR GO:0003677|GO:0006281|GO:0006310 ALX04_RS04380 e02cc92af1bab842b2156f22264b32ca 62 TIGRFAM TIGR00030 S21p: ribosomal protein bS21 3 59 6.9E-21 T 28-03-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 ALX04_RS04380 e02cc92af1bab842b2156f22264b32ca 62 Hamap MF_00358 30S ribosomal protein S21 [rpsU]. 1 57 21.603 T 28-03-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 ALX04_RS04380 e02cc92af1bab842b2156f22264b32ca 62 Gene3D G3DSA:1.20.5.1150 16 60 9.6E-15 T 28-03-2018 ALX04_RS04380 e02cc92af1bab842b2156f22264b32ca 62 PRINTS PR00976 Ribosomal protein S21 family signature 37 47 6.5E-14 T 28-03-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 ALX04_RS04380 e02cc92af1bab842b2156f22264b32ca 62 PRINTS PR00976 Ribosomal protein S21 family signature 25 35 6.5E-14 T 28-03-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 ALX04_RS04380 e02cc92af1bab842b2156f22264b32ca 62 PRINTS PR00976 Ribosomal protein S21 family signature 5 13 6.5E-14 T 28-03-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 ALX04_RS04380 e02cc92af1bab842b2156f22264b32ca 62 PRINTS PR00976 Ribosomal protein S21 family signature 13 22 6.5E-14 T 28-03-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 ALX04_RS04380 e02cc92af1bab842b2156f22264b32ca 62 ProDom PD005521 RIBOSOMAL S21 RIBONUCLEOPROTEIN 30S S21P A SSU SUBUNIT SEQUENCING DIRECT 16 52 2.0E-13 T 28-03-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 ALX04_RS04380 e02cc92af1bab842b2156f22264b32ca 62 Pfam PF01165 Ribosomal protein S21 5 56 1.4E-20 T 28-03-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 ALX04_RS04380 e02cc92af1bab842b2156f22264b32ca 62 ProSitePatterns PS01181 Ribosomal protein S21 signature. 13 25 - T 28-03-2018 IPR018278 Ribosomal protein S21, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 ALX04_RS14830 00ed06684a948074437d236d2f4c839d 230 SMART SM00986 50 210 5.7E-40 T 28-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 ALX04_RS14830 00ed06684a948074437d236d2f4c839d 230 Gene3D G3DSA:3.40.470.10 1 226 4.4E-96 T 28-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 ALX04_RS14830 00ed06684a948074437d236d2f4c839d 230 SMART SM00987 50 210 5.7E-40 T 28-03-2018 ALX04_RS14830 00ed06684a948074437d236d2f4c839d 230 TIGRFAM TIGR00628 ung: uracil-DNA glycosylase 7 212 2.9E-78 T 28-03-2018 IPR002043 Uracil-DNA glycosylase family 1 GO:0004844|GO:0006281|GO:0006284 Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 ALX04_RS14830 00ed06684a948074437d236d2f4c839d 230 ProSitePatterns PS00130 Uracil-DNA glycosylase signature. 58 67 - T 28-03-2018 IPR018085 Uracil-DNA glycosylase, active site GO:0006281|GO:0016799 Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 ALX04_RS14830 00ed06684a948074437d236d2f4c839d 230 SUPERFAMILY SSF52141 4 222 1.26E-91 T 28-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 ALX04_RS14830 00ed06684a948074437d236d2f4c839d 230 Pfam PF03167 Uracil DNA glycosylase superfamily 55 208 1.4E-19 T 28-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 ALX04_RS14830 00ed06684a948074437d236d2f4c839d 230 Hamap MF_00148 Uracil-DNA glycosylase [ung]. 6 221 39.679 T 28-03-2018 IPR002043 Uracil-DNA glycosylase family 1 GO:0004844|GO:0006281|GO:0006284 Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 ALX04_RS02635 10fcd47382df4aba30d598001ca55840 448 ProSitePatterns PS00181 Glutamine synthetase putative ATP-binding region signature. 236 251 - T 28-03-2018 IPR027303 Glutamine synthetase, glycine-rich site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 ALX04_RS02635 10fcd47382df4aba30d598001ca55840 448 Gene3D G3DSA:3.30.590.10 107 448 5.8E-124 T 28-03-2018 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 ALX04_RS02635 10fcd47382df4aba30d598001ca55840 448 Pfam PF00120 Glutamine synthetase, catalytic domain 108 444 1.2E-133 T 28-03-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 ALX04_RS02635 10fcd47382df4aba30d598001ca55840 448 Pfam PF03951 Glutamine synthetase, beta-Grasp domain 19 100 3.8E-30 T 28-03-2018 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 ALX04_RS02635 10fcd47382df4aba30d598001ca55840 448 Gene3D G3DSA:3.10.20.70 4 106 2.9E-35 T 28-03-2018 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 ALX04_RS02635 10fcd47382df4aba30d598001ca55840 448 TIGRFAM TIGR00653 GlnA: glutamine synthetase, type I 10 445 7.2E-168 T 28-03-2018 IPR004809 Glutamine synthetase type I GO:0004356|GO:0005737|GO:0009399 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 ALX04_RS02635 10fcd47382df4aba30d598001ca55840 448 SUPERFAMILY SSF54368 8 106 7.19E-32 T 28-03-2018 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 ALX04_RS02635 10fcd47382df4aba30d598001ca55840 448 SUPERFAMILY SSF55931 107 446 1.57E-123 T 28-03-2018 ALX04_RS02635 10fcd47382df4aba30d598001ca55840 448 ProSitePatterns PS00180 Glutamine synthetase signature 1. 54 72 - T 28-03-2018 IPR027302 Glutamine synthetase, N-terminal conserved site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 ALX04_RS02635 10fcd47382df4aba30d598001ca55840 448 SMART SM01230 107 358 2.5E-135 T 28-03-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 ALX04_RS06160 291a3927b4edd1ac913fa476b01b55df 213 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 8 105 1.2E-29 T 28-03-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 ALX04_RS06160 291a3927b4edd1ac913fa476b01b55df 213 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 30 208 6.8E-24 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 ALX04_RS06160 291a3927b4edd1ac913fa476b01b55df 213 Gene3D G3DSA:1.10.3720.10 2 213 6.8E-42 T 28-03-2018 ALX04_RS06160 291a3927b4edd1ac913fa476b01b55df 213 SUPERFAMILY SSF161098 10 198 7.33E-43 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 ALX04_RS11225 e238536da89dc2500ceb530ac92fd485 665 Gene3D G3DSA:3.40.50.970 5 362 4.8E-108 T 28-03-2018 ALX04_RS11225 e238536da89dc2500ceb530ac92fd485 665 TIGRFAM TIGR00232 tktlase_bact: transketolase 10 663 1.0E-281 T 28-03-2018 IPR005478 Transketolase, bacterial-like GO:0004802 KEGG: 00030+2.2.1.1|KEGG: 00710+2.2.1.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|MetaCyc: PWY-6901 ALX04_RS11225 e238536da89dc2500ceb530ac92fd485 665 ProSitePatterns PS00801 Transketolase signature 1. 14 34 - T 28-03-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 ALX04_RS11225 e238536da89dc2500ceb530ac92fd485 665 Pfam PF00456 Transketolase, thiamine diphosphate binding domain 7 336 1.2E-145 T 28-03-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 ALX04_RS11225 e238536da89dc2500ceb530ac92fd485 665 ProSitePatterns PS00802 Transketolase signature 2. 467 483 - T 28-03-2018 IPR020826 Transketolase binding site KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 ALX04_RS11225 e238536da89dc2500ceb530ac92fd485 665 Pfam PF02780 Transketolase, C-terminal domain 549 655 4.2E-7 T 28-03-2018 IPR033248 Transketolase, C-terminal domain ALX04_RS11225 e238536da89dc2500ceb530ac92fd485 665 Gene3D G3DSA:3.40.50.920 542 664 3.8E-27 T 28-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 ALX04_RS11225 e238536da89dc2500ceb530ac92fd485 665 SUPERFAMILY SSF52518 343 526 3.12E-64 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold ALX04_RS11225 e238536da89dc2500ceb530ac92fd485 665 SMART SM00861 354 525 7.0E-64 T 28-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain ALX04_RS11225 e238536da89dc2500ceb530ac92fd485 665 SUPERFAMILY SSF52518 7 324 1.06E-113 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold ALX04_RS11225 e238536da89dc2500ceb530ac92fd485 665 Gene3D G3DSA:3.40.50.970 363 541 1.1E-42 T 28-03-2018 ALX04_RS11225 e238536da89dc2500ceb530ac92fd485 665 SUPERFAMILY SSF52922 534 664 3.4E-37 T 28-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 ALX04_RS11225 e238536da89dc2500ceb530ac92fd485 665 Pfam PF02779 Transketolase, pyrimidine binding domain 354 524 1.4E-43 T 28-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain ALX04_RS05565 d386502af7537de6ab2e0c67281bdbe8 319 Gene3D G3DSA:1.20.58.340 253 319 1.5E-10 T 28-03-2018 ALX04_RS05565 d386502af7537de6ab2e0c67281bdbe8 319 SUPERFAMILY SSF143865 7 254 9.94E-30 T 28-03-2018 ALX04_RS05565 d386502af7537de6ab2e0c67281bdbe8 319 SUPERFAMILY SSF144083 255 315 1.26E-14 T 28-03-2018 ALX04_RS05565 d386502af7537de6ab2e0c67281bdbe8 319 Gene3D G3DSA:3.30.460.20 5 135 8.8E-17 T 28-03-2018 ALX04_RS05565 d386502af7537de6ab2e0c67281bdbe8 319 Pfam PF01544 CorA-like Mg2+ transporter protein 22 314 1.7E-52 T 28-03-2018 IPR002523 Mg2+ transporter protein, CorA-like/Zinc transport protein ZntB GO:0016020|GO:0030001|GO:0046873|GO:0055085 ALX04_RS05565 d386502af7537de6ab2e0c67281bdbe8 319 Gene3D G3DSA:1.20.58.340 138 252 9.1E-8 T 28-03-2018 ALX04_RS05080 4bbf98ac8e595abf7a1f116ef93362e0 311 SUPERFAMILY SSF56281 1 305 1.76E-83 T 28-03-2018 IPR001279 Metallo-beta-lactamase ALX04_RS05080 4bbf98ac8e595abf7a1f116ef93362e0 311 Gene3D G3DSA:3.60.15.10 1 311 8.5E-61 T 28-03-2018 IPR001279 Metallo-beta-lactamase ALX04_RS05080 4bbf98ac8e595abf7a1f116ef93362e0 311 Pfam PF12706 Beta-lactamase superfamily domain 202 271 4.5E-7 T 28-03-2018 IPR001279 Metallo-beta-lactamase ALX04_RS05080 4bbf98ac8e595abf7a1f116ef93362e0 311 Pfam PF00753 Metallo-beta-lactamase superfamily 16 84 8.5E-9 T 28-03-2018 IPR001279 Metallo-beta-lactamase ALX04_RS05080 4bbf98ac8e595abf7a1f116ef93362e0 311 TIGRFAM TIGR02651 RNase_Z: ribonuclease Z 3 305 1.6E-115 T 28-03-2018 IPR013471 Ribonuclease Z/BN GO:0016891|GO:0042779 ALX04_RS05080 4bbf98ac8e595abf7a1f116ef93362e0 311 Hamap MF_01818 Ribonuclease BN [rbn]. 1 305 41.518 T 28-03-2018 IPR013471 Ribonuclease Z/BN GO:0016891|GO:0042779 ALX04_RS04500 9b9f8888386beccc2f8853f218b5217f 508 Pfam PF13193 AMP-binding enzyme C-terminal domain 415 495 1.2E-7 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain ALX04_RS04500 9b9f8888386beccc2f8853f218b5217f 508 Gene3D G3DSA:3.40.50.980 3 154 2.4E-28 T 28-03-2018 ALX04_RS04500 9b9f8888386beccc2f8853f218b5217f 508 TIGRFAM TIGR01734 D-ala-DACP-lig: D-alanine--poly(phosphoribitol) ligase, subunit 1 4 506 4.9E-231 T 28-03-2018 IPR010072 D-alanine--poly(phosphoribitol) ligase subunit 1 GO:0005524|GO:0047473|GO:0070395 KEGG: 00473+6.1.1.13 ALX04_RS04500 9b9f8888386beccc2f8853f218b5217f 508 SUPERFAMILY SSF56801 4 506 5.1E-126 T 28-03-2018 ALX04_RS04500 9b9f8888386beccc2f8853f218b5217f 508 Pfam PF00501 AMP-binding enzyme 11 406 8.6E-87 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 ALX04_RS04500 9b9f8888386beccc2f8853f218b5217f 508 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 30 431 4.0E-109 T 28-03-2018 IPR010071 Amino acid adenylation domain ALX04_RS04500 9b9f8888386beccc2f8853f218b5217f 508 ProSitePatterns PS00455 Putative AMP-binding domain signature. 149 160 - T 28-03-2018 IPR020845 AMP-binding, conserved site ALX04_RS04500 9b9f8888386beccc2f8853f218b5217f 508 Gene3D G3DSA:2.30.38.10 323 399 4.0E-21 T 28-03-2018 ALX04_RS04500 9b9f8888386beccc2f8853f218b5217f 508 Hamap MF_00593 D-alanine--poly(phosphoribitol) ligase subunit 1 [dltA]. 1 507 272.998 T 28-03-2018 IPR010072 D-alanine--poly(phosphoribitol) ligase subunit 1 GO:0005524|GO:0047473|GO:0070395 KEGG: 00473+6.1.1.13 ALX04_RS04500 9b9f8888386beccc2f8853f218b5217f 508 Gene3D G3DSA:3.40.50.980 155 318 8.3E-36 T 28-03-2018 ALX04_RS04500 9b9f8888386beccc2f8853f218b5217f 508 Gene3D G3DSA:3.30.300.30 400 507 4.1E-23 T 28-03-2018 ALX04_RS03075 a65a76148ecfeddb05e12f171561300e 252 Gene3D G3DSA:3.40.50.720 1 252 1.3E-45 T 28-03-2018 ALX04_RS03075 a65a76148ecfeddb05e12f171561300e 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 157 176 4.5E-5 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR ALX04_RS03075 a65a76148ecfeddb05e12f171561300e 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 178 195 4.5E-5 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR ALX04_RS03075 a65a76148ecfeddb05e12f171561300e 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 213 233 4.5E-5 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR ALX04_RS03075 a65a76148ecfeddb05e12f171561300e 252 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 14 250 5.6E-78 T 28-03-2018 ALX04_RS03075 a65a76148ecfeddb05e12f171561300e 252 SUPERFAMILY SSF51735 7 251 8.26E-61 T 28-03-2018 IPR016040 NAD(P)-binding domain ALX04_RS03075 a65a76148ecfeddb05e12f171561300e 252 PIRSF PIRSF000094 2 252 5.2E-93 T 28-03-2018 IPR014358 Enoyl-[acyl-carrier-protein] reductase (NADH) GO:0004318|GO:0006633|GO:0055114 KEGG: 00061+1.3.1.9|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 ALX04_RS02270 f29fd6140a37d19097d057e8556f96c3 433 Pfam PF01458 Uncharacterized protein family (UPF0051) 180 402 2.5E-54 T 28-03-2018 IPR000825 SUF system FeS cluster assembly, SufBD GO:0016226 ALX04_RS02270 f29fd6140a37d19097d057e8556f96c3 433 TIGRFAM TIGR01981 sufD: FeS assembly protein SufD 144 419 6.8E-84 T 28-03-2018 IPR011542 SUF system FeS cluster assembly, SufD GO:0016226 ALX04_RS02270 f29fd6140a37d19097d057e8556f96c3 433 SUPERFAMILY SSF101960 18 429 2.09E-106 T 28-03-2018 ALX04_RS08480 df0e289ac318a3808480fe7996156db7 405 Pfam PF12698 ABC-2 family transporter protein 19 374 1.0E-37 T 28-03-2018 ALX04_RS08480 df0e289ac318a3808480fe7996156db7 405 Gene3D G3DSA:3.40.190.10 45 150 1.2E-11 T 28-03-2018 ALX04_RS15360 a8ea6fbe9f5fe7d77f2e24a3dccb25a3 110 SUPERFAMILY SSF46973 5 103 2.35E-18 T 28-03-2018 IPR003188 Phosphotransferase system, lactose/cellobiose-type IIA subunit GO:0009401 ALX04_RS15360 a8ea6fbe9f5fe7d77f2e24a3dccb25a3 110 Pfam PF02255 PTS system, Lactose/Cellobiose specific IIA subunit 11 102 7.7E-18 T 28-03-2018 IPR003188 Phosphotransferase system, lactose/cellobiose-type IIA subunit GO:0009401 ALX04_RS15360 a8ea6fbe9f5fe7d77f2e24a3dccb25a3 110 Gene3D G3DSA:1.20.58.80 6 104 4.5E-16 T 28-03-2018 IPR003188 Phosphotransferase system, lactose/cellobiose-type IIA subunit GO:0009401 ALX04_RS07940 184f70df51ffd459cfe2892701a1f89e 431 SUPERFAMILY SSF52218 1 173 1.02E-39 T 28-03-2018 IPR029039 Flavoprotein-like domain ALX04_RS07940 184f70df51ffd459cfe2892701a1f89e 431 Pfam PF03358 NADPH-dependent FMN reductase 1 146 4.5E-34 T 28-03-2018 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 ALX04_RS07940 184f70df51ffd459cfe2892701a1f89e 431 Gene3D G3DSA:3.40.50.360 1 183 2.9E-30 T 28-03-2018 IPR029039 Flavoprotein-like domain ALX04_RS07940 184f70df51ffd459cfe2892701a1f89e 431 Pfam PF13596 PAS domain 245 353 2.1E-34 T 28-03-2018 ALX04_RS07940 184f70df51ffd459cfe2892701a1f89e 431 Gene3D G3DSA:1.20.120.520 184 259 3.8E-5 T 28-03-2018 ALX04_RS05350 ade6c1db6afc0ecb0eb7b3a01b647fb5 186 Hamap MF_00163 Peptide deformylase [def]. 3 185 25.47 T 28-03-2018 IPR023635 Peptide deformylase ALX04_RS05350 ade6c1db6afc0ecb0eb7b3a01b647fb5 186 TIGRFAM TIGR00079 pept_deformyl: peptide deformylase 5 178 3.4E-40 T 28-03-2018 IPR023635 Peptide deformylase ALX04_RS05350 ade6c1db6afc0ecb0eb7b3a01b647fb5 186 Gene3D G3DSA:3.90.45.10 3 185 3.5E-52 T 28-03-2018 IPR023635 Peptide deformylase ALX04_RS05350 ade6c1db6afc0ecb0eb7b3a01b647fb5 186 PRINTS PR01576 Peptide deformylase signature 143 172 8.1E-26 T 28-03-2018 IPR023635 Peptide deformylase ALX04_RS05350 ade6c1db6afc0ecb0eb7b3a01b647fb5 186 PRINTS PR01576 Peptide deformylase signature 47 76 8.1E-26 T 28-03-2018 IPR023635 Peptide deformylase ALX04_RS05350 ade6c1db6afc0ecb0eb7b3a01b647fb5 186 PRINTS PR01576 Peptide deformylase signature 124 142 8.1E-26 T 28-03-2018 IPR023635 Peptide deformylase ALX04_RS05350 ade6c1db6afc0ecb0eb7b3a01b647fb5 186 PRINTS PR01576 Peptide deformylase signature 111 122 8.1E-26 T 28-03-2018 IPR023635 Peptide deformylase ALX04_RS05350 ade6c1db6afc0ecb0eb7b3a01b647fb5 186 PIRSF PIRSF004749 2 185 2.8E-43 T 28-03-2018 IPR023635 Peptide deformylase ALX04_RS05350 ade6c1db6afc0ecb0eb7b3a01b647fb5 186 Pfam PF01327 Polypeptide deformylase 4 172 5.7E-45 T 28-03-2018 IPR023635 Peptide deformylase ALX04_RS05350 ade6c1db6afc0ecb0eb7b3a01b647fb5 186 SUPERFAMILY SSF56420 2 183 6.28E-56 T 28-03-2018 IPR023635 Peptide deformylase ALX04_RS03930 ada9a32c0937c704ef0ad44450468ad8 210 SMART SM00257 166 210 3.3E-7 T 28-03-2018 IPR018392 LysM domain ALX04_RS03930 ada9a32c0937c704ef0ad44450468ad8 210 SUPERFAMILY SSF54106 164 209 3.27E-6 T 28-03-2018 IPR018392 LysM domain ALX04_RS03930 ada9a32c0937c704ef0ad44450468ad8 210 Pfam PF01476 LysM domain 168 209 1.4E-7 T 28-03-2018 IPR018392 LysM domain ALX04_RS03930 ada9a32c0937c704ef0ad44450468ad8 210 Gene3D G3DSA:3.10.350.10 152 210 3.1E-9 T 28-03-2018 ALX04_RS03280 b74237bceb8308b6d3cbd233dffc2a76 290 Pfam PF15983 Domain of unknown function (DUF4767) 153 287 1.3E-42 T 28-03-2018 IPR031927 Domain of unknown function DUF4767 ALX04_RS03280 b74237bceb8308b6d3cbd233dffc2a76 290 Gene3D G3DSA:2.20.28.20 2 27 3.0E-5 T 28-03-2018 ALX04_RS03280 b74237bceb8308b6d3cbd233dffc2a76 290 Pfam PF13240 zinc-ribbon domain 2 24 3.0E-8 T 28-03-2018 IPR026870 Zinc-ribbon domain Reactome: R-HSA-202670 ALX04_RS01760 6921a462fc45ce4c41baa8f931f75ad9 312 SUPERFAMILY SSF103481 193 295 6.41E-9 T 28-03-2018 ALX04_RS01760 6921a462fc45ce4c41baa8f931f75ad9 312 Pfam PF00892 EamA-like transporter family 160 291 7.7E-12 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 ALX04_RS01760 6921a462fc45ce4c41baa8f931f75ad9 312 Pfam PF00892 EamA-like transporter family 6 147 9.7E-14 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 ALX04_RS01760 6921a462fc45ce4c41baa8f931f75ad9 312 SUPERFAMILY SSF103481 42 150 9.16E-7 T 28-03-2018 ALX04_RS09580 85ebd044efe384d403190b5c974a1eda 94 Gene3D G3DSA:2.40.30.100 4 91 4.7E-23 T 28-03-2018 IPR015018 Protein of unknown function DUF1905 ALX04_RS09580 85ebd044efe384d403190b5c974a1eda 94 Pfam PF08922 Domain of unknown function (DUF1905) 6 90 1.1E-20 T 28-03-2018 IPR015018 Protein of unknown function DUF1905 ALX04_RS09580 85ebd044efe384d403190b5c974a1eda 94 SUPERFAMILY SSF141694 3 91 1.73E-22 T 28-03-2018 ALX04_RS09555 1f92910271322be62d9a787a0a498a56 193 Gene3D G3DSA:1.10.357.10 3 193 1.1E-23 T 28-03-2018 ALX04_RS09555 1f92910271322be62d9a787a0a498a56 193 SUPERFAMILY SSF46689 5 68 6.8E-12 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 ALX04_RS09555 1f92910271322be62d9a787a0a498a56 193 Pfam PF00440 Bacterial regulatory proteins, tetR family 16 57 2.9E-8 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 ALX04_RS02875 cba7230f81c179364f87a70d64258287 512 Gene3D G3DSA:3.40.50.300 299 508 3.3E-45 T 28-03-2018 ALX04_RS02875 cba7230f81c179364f87a70d64258287 512 SMART SM00963 207 288 3.0E-22 T 28-03-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 ALX04_RS02875 cba7230f81c179364f87a70d64258287 512 TIGRFAM TIGR00064 ftsY: signal recognition particle-docking protein FtsY 232 506 9.1E-113 T 28-03-2018 IPR004390 Signal-recognition particle receptor FtsY GO:0006614 ALX04_RS02875 cba7230f81c179364f87a70d64258287 512 Pfam PF00448 SRP54-type protein, GTPase domain 306 506 2.6E-80 T 28-03-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 ALX04_RS02875 cba7230f81c179364f87a70d64258287 512 SMART SM00962 306 507 3.9E-124 T 28-03-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 ALX04_RS02875 cba7230f81c179364f87a70d64258287 512 SUPERFAMILY SSF47364 204 281 1.06E-18 T 28-03-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 ALX04_RS02875 cba7230f81c179364f87a70d64258287 512 Hamap MF_00920 Signal recognition particle receptor FtsY [ftsY]. 231 507 65.191 T 28-03-2018 IPR004390 Signal-recognition particle receptor FtsY GO:0006614 ALX04_RS02875 cba7230f81c179364f87a70d64258287 512 Pfam PF02881 SRP54-type protein, helical bundle domain 218 284 1.6E-13 T 28-03-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 ALX04_RS02875 cba7230f81c179364f87a70d64258287 512 SMART SM00382 305 497 2.7E-10 T 28-03-2018 IPR003593 AAA+ ATPase domain ALX04_RS02875 cba7230f81c179364f87a70d64258287 512 SUPERFAMILY SSF52540 300 506 4.26E-53 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase ALX04_RS02875 cba7230f81c179364f87a70d64258287 512 Gene3D G3DSA:1.20.120.140 194 286 7.5E-20 T 28-03-2018 ALX04_RS10385 aeb181ae6c3b24bf17e97398a47b9b5f 752 SUPERFAMILY SSF51998 6 751 7.94E-269 T 28-03-2018 ALX04_RS10385 aeb181ae6c3b24bf17e97398a47b9b5f 752 ProSitePatterns PS00850 Glycine radical domain signature. 722 730 - T 28-03-2018 IPR019777 Formate C-acetyltransferase glycine radical, conserved site ALX04_RS10385 aeb181ae6c3b24bf17e97398a47b9b5f 752 PIRSF PIRSF000379 9 752 0.0 T 28-03-2018 IPR005949 Formate acetyltransferase GO:0005737|GO:0005975|GO:0008861 KEGG: 00620+2.3.1.54|KEGG: 00640+2.3.1.54|KEGG: 00650+2.3.1.54|MetaCyc: PWY-5480|MetaCyc: PWY-5485|MetaCyc: PWY-5493 ALX04_RS10385 aeb181ae6c3b24bf17e97398a47b9b5f 752 Gene3D G3DSA:3.20.70.20 3 752 2.2E-275 T 28-03-2018 ALX04_RS10385 aeb181ae6c3b24bf17e97398a47b9b5f 752 TIGRFAM TIGR01255 pyr_form_ly_1: formate acetyltransferase 12 752 0.0 T 28-03-2018 IPR005949 Formate acetyltransferase GO:0005737|GO:0005975|GO:0008861 KEGG: 00620+2.3.1.54|KEGG: 00640+2.3.1.54|KEGG: 00650+2.3.1.54|MetaCyc: PWY-5480|MetaCyc: PWY-5485|MetaCyc: PWY-5493 ALX04_RS10385 aeb181ae6c3b24bf17e97398a47b9b5f 752 Pfam PF02901 Pyruvate formate lyase-like 25 611 8.8E-188 T 28-03-2018 IPR004184 Pyruvate formate lyase domain GO:0003824 ALX04_RS10385 aeb181ae6c3b24bf17e97398a47b9b5f 752 Pfam PF01228 Glycine radical 627 732 3.9E-37 T 28-03-2018 IPR001150 Glycine radical domain GO:0003824|GO:0008152 ALX04_RS03820 0dd43541e9c97b9742f222cf72aed26f 309 SUPERFAMILY SSF53850 89 297 1.23E-22 T 28-03-2018 ALX04_RS03820 0dd43541e9c97b9742f222cf72aed26f 309 Pfam PF03466 LysR substrate binding domain 119 297 1.4E-12 T 28-03-2018 IPR005119 LysR, substrate-binding ALX04_RS03820 0dd43541e9c97b9742f222cf72aed26f 309 SUPERFAMILY SSF46785 1 97 9.1E-23 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS03820 0dd43541e9c97b9742f222cf72aed26f 309 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 5.3E-7 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 ALX04_RS03820 0dd43541e9c97b9742f222cf72aed26f 309 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 5.3E-7 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 ALX04_RS03820 0dd43541e9c97b9742f222cf72aed26f 309 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 5.3E-7 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 ALX04_RS03820 0dd43541e9c97b9742f222cf72aed26f 309 Gene3D G3DSA:3.40.190.10 84 187 2.2E-7 T 28-03-2018 ALX04_RS03820 0dd43541e9c97b9742f222cf72aed26f 309 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 62 1.2E-20 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 ALX04_RS03820 0dd43541e9c97b9742f222cf72aed26f 309 Gene3D G3DSA:1.10.10.10 1 83 5.6E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS03820 0dd43541e9c97b9742f222cf72aed26f 309 Gene3D G3DSA:3.40.190.10 188 271 2.2E-4 T 28-03-2018 ALX04_RS07920 0986d213489a8521e704128165637330 84 TIGRFAM TIGR00302 TIGR00302: phosphoribosylformylglycinamidine synthase, purS protein 2 80 2.2E-26 T 28-03-2018 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 ALX04_RS07920 0986d213489a8521e704128165637330 84 Pfam PF02700 Phosphoribosylformylglycinamidine (FGAM) synthase 4 78 2.3E-29 T 28-03-2018 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 ALX04_RS07920 0986d213489a8521e704128165637330 84 Gene3D G3DSA:3.30.1280.10 2 80 4.4E-27 T 28-03-2018 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 ALX04_RS07920 0986d213489a8521e704128165637330 84 Hamap MF_01926 Phosphoribosylformylglycinamidine synthase subunit PurS [purS]. 2 78 20.452 T 28-03-2018 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 ALX04_RS07920 0986d213489a8521e704128165637330 84 ProDom PD010362 PHOSPHORIBOSYLFORMYLGLYCINAMIDINE PURS SYNTHETASE SYNTHASE COMPONENT SYNTHASE LIGASE FGAM UPF0062 I 11 81 3.0E-36 T 28-03-2018 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 ALX04_RS07920 0986d213489a8521e704128165637330 84 SUPERFAMILY SSF82697 1 79 5.76E-28 T 28-03-2018 ALX04_RS10300 fe1ffcda67aa46a032db757b52b3fc87 175 SUPERFAMILY SSF48150 18 172 1.31E-42 T 28-03-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 ALX04_RS10300 fe1ffcda67aa46a032db757b52b3fc87 175 Pfam PF03352 Methyladenine glycosylase 15 173 7.0E-38 T 28-03-2018 IPR005019 Methyladenine glycosylase GO:0006284|GO:0008725 ALX04_RS10300 fe1ffcda67aa46a032db757b52b3fc87 175 Gene3D G3DSA:1.10.340.30 10 175 3.3E-40 T 28-03-2018 ALX04_RS02805 54ad90e3ee9debfbb78caaeb58779160 447 SUPERFAMILY SSF48013 7 130 4.84E-31 T 28-03-2018 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 ALX04_RS02805 54ad90e3ee9debfbb78caaeb58779160 447 ProSitePatterns PS01153 NOL1/NOP2/sun family signature. 327 338 - T 28-03-2018 IPR018314 Bacterial Fmu (Sun)/eukaryotic nucleolar NOL1/Nop2p, conserved site GO:0003723|GO:0008168 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 ALX04_RS02805 54ad90e3ee9debfbb78caaeb58779160 447 Pfam PF01189 16S rRNA methyltransferase RsmB/F 247 445 2.8E-55 T 28-03-2018 IPR001678 SAM-dependent methyltransferase RsmB/NOP2-type GO:0008168 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 ALX04_RS02805 54ad90e3ee9debfbb78caaeb58779160 447 Gene3D G3DSA:3.30.70.1170 171 237 2.1E-7 T 28-03-2018 ALX04_RS02805 54ad90e3ee9debfbb78caaeb58779160 447 Pfam PF01029 NusB family 8 129 2.8E-23 T 28-03-2018 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 ALX04_RS02805 54ad90e3ee9debfbb78caaeb58779160 447 TIGRFAM TIGR00563 rsmB: 16S rRNA (cytosine(967)-C(5))-methyltransferase 9 447 1.2E-115 T 28-03-2018 IPR004573 rRNA small subunit methyltransferase B GO:0006364|GO:0008649 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 ALX04_RS02805 54ad90e3ee9debfbb78caaeb58779160 447 Gene3D G3DSA:1.10.940.10 4 144 1.3E-22 T 28-03-2018 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 ALX04_RS02805 54ad90e3ee9debfbb78caaeb58779160 447 Gene3D G3DSA:3.40.50.150 238 447 5.9E-59 T 28-03-2018 ALX04_RS02805 54ad90e3ee9debfbb78caaeb58779160 447 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 228 242 3.7E-29 T 28-03-2018 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 ALX04_RS02805 54ad90e3ee9debfbb78caaeb58779160 447 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 257 267 3.7E-29 T 28-03-2018 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 ALX04_RS02805 54ad90e3ee9debfbb78caaeb58779160 447 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 429 446 3.7E-29 T 28-03-2018 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 ALX04_RS02805 54ad90e3ee9debfbb78caaeb58779160 447 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 328 340 3.7E-29 T 28-03-2018 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 ALX04_RS02805 54ad90e3ee9debfbb78caaeb58779160 447 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 378 394 3.7E-29 T 28-03-2018 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 ALX04_RS02805 54ad90e3ee9debfbb78caaeb58779160 447 SUPERFAMILY SSF53335 142 447 1.39E-67 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase ALX04_RS12125 8d30e99e0d7e7812536a7bf82c3d2c78 157 SUPERFAMILY SSF46785 36 154 2.68E-14 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS12125 8d30e99e0d7e7812536a7bf82c3d2c78 157 Gene3D G3DSA:1.10.10.10 6 157 4.0E-14 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS12125 8d30e99e0d7e7812536a7bf82c3d2c78 157 SMART SM00347 41 142 0.0076 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 ALX04_RS04545 59e900575f7a952704f2c89ee236850e 307 SUPERFAMILY SSF55120 1 226 7.77E-76 T 28-03-2018 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 ALX04_RS04545 59e900575f7a952704f2c89ee236850e 307 Gene3D G3DSA:3.30.2350.10 1 227 5.2E-77 T 28-03-2018 ALX04_RS04545 59e900575f7a952704f2c89ee236850e 307 Hamap MF_01080 tRNA pseudouridine synthase B [truB]. 2 304 18.746 T 28-03-2018 IPR014780 tRNA pseudouridine synthase II, TruB GO:0001522|GO:0003723|GO:0009451|GO:0009982 ALX04_RS04545 59e900575f7a952704f2c89ee236850e 307 Pfam PF16198 tRNA pseudouridylate synthase B C-terminal domain 181 239 7.9E-11 T 28-03-2018 IPR032819 tRNA pseudouridylate synthase B, C-terminal Reactome: R-HSA-171319|Reactome: R-HSA-6790901 ALX04_RS04545 59e900575f7a952704f2c89ee236850e 307 TIGRFAM TIGR00431 TruB: tRNA pseudouridine(55) synthase 3 218 5.9E-76 T 28-03-2018 IPR014780 tRNA pseudouridine synthase II, TruB GO:0001522|GO:0003723|GO:0009451|GO:0009982 ALX04_RS04545 59e900575f7a952704f2c89ee236850e 307 Pfam PF01509 TruB family pseudouridylate synthase (N terminal domain) 24 180 1.0E-53 T 28-03-2018 IPR002501 Pseudouridine synthase II, N-terminal GO:0006396 ALX04_RS11680 ef9664adf1874409b9cfa3fe758c839a 255 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 6 222 5.1E-23 T 28-03-2018 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 ALX04_RS11680 ef9664adf1874409b9cfa3fe758c839a 255 Pfam PF08282 haloacid dehalogenase-like hydrolase 6 248 5.0E-51 T 28-03-2018 IPR023214 HAD-like domain ALX04_RS11680 ef9664adf1874409b9cfa3fe758c839a 255 SUPERFAMILY SSF56784 5 252 3.59E-52 T 28-03-2018 IPR023214 HAD-like domain ALX04_RS11680 ef9664adf1874409b9cfa3fe758c839a 255 Gene3D G3DSA:3.40.50.1000 2 254 1.2E-35 T 28-03-2018 IPR023214 HAD-like domain ALX04_RS11680 ef9664adf1874409b9cfa3fe758c839a 255 TIGRFAM TIGR00099 Cof-subfamily: Cof-like hydrolase 5 248 6.4E-54 T 28-03-2018 IPR000150 Cof family GO:0016787 ALX04_RS12215 d3eb550626303191bb193f092c5465e6 238 SMART SM00345 8 67 5.6E-15 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 ALX04_RS12215 d3eb550626303191bb193f092c5465e6 238 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 27 41 3.6E-5 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 ALX04_RS12215 d3eb550626303191bb193f092c5465e6 238 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 41 57 3.6E-5 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 ALX04_RS12215 d3eb550626303191bb193f092c5465e6 238 Gene3D G3DSA:1.10.10.10 2 69 1.8E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS12215 d3eb550626303191bb193f092c5465e6 238 Pfam PF00392 Bacterial regulatory proteins, gntR family 4 67 9.8E-19 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 ALX04_RS12215 d3eb550626303191bb193f092c5465e6 238 SUPERFAMILY SSF64288 55 233 6.75E-36 T 28-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain ALX04_RS12215 d3eb550626303191bb193f092c5465e6 238 SMART SM00866 92 230 2.1E-31 T 28-03-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 ALX04_RS12215 d3eb550626303191bb193f092c5465e6 238 Gene3D G3DSA:3.40.1410.10 76 237 3.7E-34 T 28-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain ALX04_RS12215 d3eb550626303191bb193f092c5465e6 238 Pfam PF07702 UTRA domain 93 226 9.2E-33 T 28-03-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 ALX04_RS12215 d3eb550626303191bb193f092c5465e6 238 SUPERFAMILY SSF46785 4 69 5.45E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS15585 43b29680c6b5319d7f27b55bad042a25 300 Gene3D G3DSA:3.40.50.300 1 269 1.2E-35 T 28-03-2018 ALX04_RS15585 43b29680c6b5319d7f27b55bad042a25 300 SUPERFAMILY SSF52540 2 266 3.08E-35 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase ALX04_RS15585 43b29680c6b5319d7f27b55bad042a25 300 Pfam PF13614 AAA domain 2 184 4.6E-37 T 28-03-2018 IPR025669 AAA domain ALX04_RS06335 4f8fdd6e0d604413b5f2eeac751aec1c 370 ProSitePatterns PS00844 D-alanine--D-alanine ligase signature 2. 293 321 - T 28-03-2018 IPR000291 D-alanine--D-alanine ligase/VANA/B/C, conserved site KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 ALX04_RS06335 4f8fdd6e0d604413b5f2eeac751aec1c 370 PIRSF PIRSF039102 4 359 8.9E-125 T 28-03-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 ALX04_RS06335 4f8fdd6e0d604413b5f2eeac751aec1c 370 Pfam PF01820 D-ala D-ala ligase N-terminus 9 127 8.2E-25 T 28-03-2018 IPR011127 D-alanine--D-alanine ligase, N-terminal domain KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 ALX04_RS06335 4f8fdd6e0d604413b5f2eeac751aec1c 370 ProSitePatterns PS00843 D-alanine--D-alanine ligase signature 1. 104 115 - T 28-03-2018 IPR000291 D-alanine--D-alanine ligase/VANA/B/C, conserved site KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 ALX04_RS06335 4f8fdd6e0d604413b5f2eeac751aec1c 370 Hamap MF_00047 D-alanine--D-alanine ligase [ddl]. 7 351 38.611 T 28-03-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 ALX04_RS06335 4f8fdd6e0d604413b5f2eeac751aec1c 370 SUPERFAMILY SSF52440 6 136 1.73E-32 T 28-03-2018 IPR016185 Pre-ATP-grasp domain ALX04_RS06335 4f8fdd6e0d604413b5f2eeac751aec1c 370 SUPERFAMILY SSF56059 137 354 4.07E-53 T 28-03-2018 ALX04_RS06335 4f8fdd6e0d604413b5f2eeac751aec1c 370 Gene3D G3DSA:3.30.1490.20 143 226 8.5E-15 T 28-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 ALX04_RS06335 4f8fdd6e0d604413b5f2eeac751aec1c 370 TIGRFAM TIGR01205 D_ala_D_alaTIGR: D-alanine--D-alanine ligase 8 349 2.3E-91 T 28-03-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 ALX04_RS06335 4f8fdd6e0d604413b5f2eeac751aec1c 370 Pfam PF07478 D-ala D-ala ligase C-terminus 145 348 7.7E-66 T 28-03-2018 IPR011095 D-alanine--D-alanine ligase, C-terminal GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 ALX04_RS06335 4f8fdd6e0d604413b5f2eeac751aec1c 370 Gene3D G3DSA:3.40.50.20 1 142 3.4E-38 T 28-03-2018 ALX04_RS06335 4f8fdd6e0d604413b5f2eeac751aec1c 370 Gene3D G3DSA:3.30.470.20 227 370 4.7E-39 T 28-03-2018 ALX04_RS03675 6766fb7d5deec31a50bf6806a142d760 341 Gene3D G3DSA:3.40.50.720 159 301 2.8E-5 T 28-03-2018 ALX04_RS03675 6766fb7d5deec31a50bf6806a142d760 341 SUPERFAMILY SSF51735 136 296 3.94E-9 T 28-03-2018 IPR016040 NAD(P)-binding domain ALX04_RS03675 6766fb7d5deec31a50bf6806a142d760 341 Hamap MF_02069 Ribulose-5-phosphate reductase [tarJ]. 1 341 58.148 T 28-03-2018 IPR034710 Ribulose-5-phosphate reductase GO:0050256 ALX04_RS03675 6766fb7d5deec31a50bf6806a142d760 341 Gene3D G3DSA:3.90.180.10 4 158 4.3E-19 T 28-03-2018 ALX04_RS03675 6766fb7d5deec31a50bf6806a142d760 341 SUPERFAMILY SSF50129 16 168 9.43E-21 T 28-03-2018 IPR011032 GroES-like ALX04_RS03675 6766fb7d5deec31a50bf6806a142d760 341 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 26 129 1.0E-7 T 28-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 ALX04_RS11590 92257e7d07fafaed1ad2a6d5e1815ad6 648 Gene3D G3DSA:3.40.50.670 413 645 1.3E-96 T 28-03-2018 IPR013759 DNA topoisomerase, type IIA, central domain GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 ALX04_RS11590 92257e7d07fafaed1ad2a6d5e1815ad6 648 PRINTS PR01159 DNA gyrase subunit B signature 193 208 1.8E-70 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 ALX04_RS11590 92257e7d07fafaed1ad2a6d5e1815ad6 648 PRINTS PR01159 DNA gyrase subunit B signature 234 256 1.8E-70 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 ALX04_RS11590 92257e7d07fafaed1ad2a6d5e1815ad6 648 PRINTS PR01159 DNA gyrase subunit B signature 374 388 1.8E-70 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 ALX04_RS11590 92257e7d07fafaed1ad2a6d5e1815ad6 648 PRINTS PR01159 DNA gyrase subunit B signature 388 408 1.8E-70 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 ALX04_RS11590 92257e7d07fafaed1ad2a6d5e1815ad6 648 PRINTS PR01159 DNA gyrase subunit B signature 326 342 1.8E-70 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 ALX04_RS11590 92257e7d07fafaed1ad2a6d5e1815ad6 648 PRINTS PR01159 DNA gyrase subunit B signature 601 613 1.8E-70 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 ALX04_RS11590 92257e7d07fafaed1ad2a6d5e1815ad6 648 PRINTS PR01159 DNA gyrase subunit B signature 484 493 1.8E-70 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 ALX04_RS11590 92257e7d07fafaed1ad2a6d5e1815ad6 648 PRINTS PR01159 DNA gyrase subunit B signature 617 633 1.8E-70 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 ALX04_RS11590 92257e7d07fafaed1ad2a6d5e1815ad6 648 PRINTS PR01159 DNA gyrase subunit B signature 208 221 1.8E-70 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 ALX04_RS11590 92257e7d07fafaed1ad2a6d5e1815ad6 648 PRINTS PR01159 DNA gyrase subunit B signature 16 26 1.8E-70 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 ALX04_RS11590 92257e7d07fafaed1ad2a6d5e1815ad6 648 SUPERFAMILY SSF54211 235 405 1.02E-62 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold ALX04_RS11590 92257e7d07fafaed1ad2a6d5e1815ad6 648 PRINTS PR00418 DNA topoisomerase II family signature 538 550 9.0E-70 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 ALX04_RS11590 92257e7d07fafaed1ad2a6d5e1815ad6 648 PRINTS PR00418 DNA topoisomerase II family signature 580 596 9.0E-70 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 ALX04_RS11590 92257e7d07fafaed1ad2a6d5e1815ad6 648 PRINTS PR00418 DNA topoisomerase II family signature 123 137 9.0E-70 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 ALX04_RS11590 92257e7d07fafaed1ad2a6d5e1815ad6 648 PRINTS PR00418 DNA topoisomerase II family signature 282 295 9.0E-70 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 ALX04_RS11590 92257e7d07fafaed1ad2a6d5e1815ad6 648 PRINTS PR00418 DNA topoisomerase II family signature 518 535 9.0E-70 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 ALX04_RS11590 92257e7d07fafaed1ad2a6d5e1815ad6 648 PRINTS PR00418 DNA topoisomerase II family signature 434 448 9.0E-70 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 ALX04_RS11590 92257e7d07fafaed1ad2a6d5e1815ad6 648 PRINTS PR00418 DNA topoisomerase II family signature 80 93 9.0E-70 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 ALX04_RS11590 92257e7d07fafaed1ad2a6d5e1815ad6 648 PRINTS PR00418 DNA topoisomerase II family signature 45 60 9.0E-70 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 ALX04_RS11590 92257e7d07fafaed1ad2a6d5e1815ad6 648 PRINTS PR00418 DNA topoisomerase II family signature 500 516 9.0E-70 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 ALX04_RS11590 92257e7d07fafaed1ad2a6d5e1815ad6 648 SMART SM00387 41 187 3.1E-21 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain ALX04_RS11590 92257e7d07fafaed1ad2a6d5e1815ad6 648 SUPERFAMILY SSF55874 15 224 4.45E-70 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain ALX04_RS11590 92257e7d07fafaed1ad2a6d5e1815ad6 648 SMART SM00433 45 641 0.0 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 ALX04_RS11590 92257e7d07fafaed1ad2a6d5e1815ad6 648 Pfam PF00204 DNA gyrase B 235 404 3.5E-65 T 28-03-2018 IPR013506 DNA topoisomerase, type IIA, subunit B, domain 2 GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 ALX04_RS11590 92257e7d07fafaed1ad2a6d5e1815ad6 648 Hamap MF_01898 DNA gyrase subunit B [gyrB]. 13 648 88.868 T 28-03-2018 IPR011557 DNA gyrase, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 ALX04_RS11590 92257e7d07fafaed1ad2a6d5e1815ad6 648 SUPERFAMILY SSF56719 408 640 6.28E-86 T 28-03-2018 IPR013760 DNA topoisomerase, type IIA-like domain GO:0003918|GO:0005524 Reactome: R-HSA-4615885 ALX04_RS11590 92257e7d07fafaed1ad2a6d5e1815ad6 648 Gene3D G3DSA:3.30.565.10 28 233 8.0E-72 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain ALX04_RS11590 92257e7d07fafaed1ad2a6d5e1815ad6 648 Pfam PF01751 Toprim domain 433 544 5.2E-18 T 28-03-2018 IPR006171 TOPRIM domain ALX04_RS11590 92257e7d07fafaed1ad2a6d5e1815ad6 648 Gene3D G3DSA:3.30.230.10 234 406 2.3E-66 T 28-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup ALX04_RS11590 92257e7d07fafaed1ad2a6d5e1815ad6 648 TIGRFAM TIGR01059 gyrB: DNA gyrase, B subunit 16 648 2.9E-297 T 28-03-2018 IPR011557 DNA gyrase, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 ALX04_RS11590 92257e7d07fafaed1ad2a6d5e1815ad6 648 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 43 185 4.3E-20 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain ALX04_RS11590 92257e7d07fafaed1ad2a6d5e1815ad6 648 ProSitePatterns PS00177 DNA topoisomerase II signature. 436 444 - T 28-03-2018 IPR018522 DNA topoisomerase, type IIA, conserved site GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 ALX04_RS11590 92257e7d07fafaed1ad2a6d5e1815ad6 648 Pfam PF00986 DNA gyrase B subunit, carboxyl terminus 577 637 1.5E-28 T 28-03-2018 IPR002288 DNA gyrase B subunit, C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 ALX04_RS02030 8eb032b0d973e69d51302b4872980721 825 SUPERFAMILY SSF52540 721 810 1.84E-15 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase ALX04_RS02030 8eb032b0d973e69d51302b4872980721 825 SUPERFAMILY SSF52540 1 219 1.84E-15 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase ALX04_RS02030 8eb032b0d973e69d51302b4872980721 825 Gene3D G3DSA:3.40.50.300 651 819 0.078 T 28-03-2018 ALX04_RS02030 8eb032b0d973e69d51302b4872980721 825 Gene3D G3DSA:3.40.50.300 1 342 8.8E-16 T 28-03-2018 ALX04_RS02030 8eb032b0d973e69d51302b4872980721 825 Pfam PF13514 AAA domain 1 200 2.3E-25 T 28-03-2018 ALX04_RS02030 8eb032b0d973e69d51302b4872980721 825 Gene3D G3DSA:1.10.287.510 540 650 0.098 T 28-03-2018 ALX04_RS03160 eb86f5781a17def0af8f193aa651445b 201 Pfam PF03067 Lytic polysaccharide mono-oxygenase, cellulose-degrading 34 198 1.4E-32 T 28-03-2018 IPR004302 Cellulose/chitin-binding protein, N-terminal ALX04_RS03160 eb86f5781a17def0af8f193aa651445b 201 SUPERFAMILY SSF81296 34 200 2.24E-49 T 28-03-2018 IPR014756 Immunoglobulin E-set ALX04_RS03160 eb86f5781a17def0af8f193aa651445b 201 Gene3D G3DSA:2.70.50.50 34 201 5.4E-50 T 28-03-2018 ALX04_RS13605 ff557724755d8ce3a1ac90a2ae63a948 450 Gene3D G3DSA:1.10.3210.10 10 321 1.0E-79 T 28-03-2018 ALX04_RS13605 ff557724755d8ce3a1ac90a2ae63a948 450 Pfam PF01966 HD domain 61 188 3.3E-13 T 28-03-2018 IPR006674 HD domain ALX04_RS13605 ff557724755d8ce3a1ac90a2ae63a948 450 SMART SM00471 57 195 2.3E-13 T 28-03-2018 IPR003607 HD/PDEase domain ALX04_RS13605 ff557724755d8ce3a1ac90a2ae63a948 450 SUPERFAMILY SSF109604 8 429 2.4E-129 T 28-03-2018 ALX04_RS02880 2d558d2161592a7acdc6083996fb94d2 115 Pfam PF04297 Putative helix-turn-helix protein, YlxM / p13 like 3 104 7.2E-35 T 28-03-2018 IPR007394 Putative helix-turn-helix protein, YlxM/p13-like ALX04_RS02880 2d558d2161592a7acdc6083996fb94d2 115 SUPERFAMILY SSF88659 2 102 2.99E-32 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 ALX04_RS02880 2d558d2161592a7acdc6083996fb94d2 115 Gene3D G3DSA:1.10.10.10 1 111 6.0E-31 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS02880 2d558d2161592a7acdc6083996fb94d2 115 Hamap MF_00245 UPF0122 protein . 3 104 20.199 T 28-03-2018 IPR007394 Putative helix-turn-helix protein, YlxM/p13-like ALX04_RS12585 220224f162d2735a1458f2283d0bfcdf 110 ProSitePatterns PS00194 Thioredoxin family active site. 21 39 - T 28-03-2018 IPR017937 Thioredoxin, conserved site GO:0045454 ALX04_RS12585 220224f162d2735a1458f2283d0bfcdf 110 SUPERFAMILY SSF52833 4 103 2.43E-33 T 28-03-2018 IPR012336 Thioredoxin-like fold ALX04_RS12585 220224f162d2735a1458f2283d0bfcdf 110 PIRSF PIRSF000077 1 104 3.0E-34 T 28-03-2018 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 ALX04_RS12585 220224f162d2735a1458f2283d0bfcdf 110 TIGRFAM TIGR01068 thioredoxin: thioredoxin 11 103 1.2E-33 T 28-03-2018 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 ALX04_RS12585 220224f162d2735a1458f2283d0bfcdf 110 Gene3D G3DSA:3.40.30.10 1 110 4.5E-33 T 28-03-2018 ALX04_RS12585 220224f162d2735a1458f2283d0bfcdf 110 PRINTS PR00421 Thioredoxin family signature 20 28 1.8E-6 T 28-03-2018 ALX04_RS12585 220224f162d2735a1458f2283d0bfcdf 110 PRINTS PR00421 Thioredoxin family signature 28 37 1.8E-6 T 28-03-2018 ALX04_RS12585 220224f162d2735a1458f2283d0bfcdf 110 PRINTS PR00421 Thioredoxin family signature 68 79 1.8E-6 T 28-03-2018 ALX04_RS12585 220224f162d2735a1458f2283d0bfcdf 110 Pfam PF00085 Thioredoxin 6 102 1.9E-27 T 28-03-2018 IPR013766 Thioredoxin domain GO:0045454 ALX04_RS09060 c61332cc521ae886d6a40e1f5a934f9a 333 Pfam PF02653 Branched-chain amino acid transport system / permease component 4 272 1.2E-26 T 28-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 ALX04_RS09060 c61332cc521ae886d6a40e1f5a934f9a 333 Gene3D G3DSA:1.10.3470.10 1 282 2.4E-29 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like ALX04_RS03415 04c6f1c7d920ea58fff702af95176615 381 Gene3D G3DSA:3.40.50.150 161 380 2.9E-27 T 28-03-2018 ALX04_RS03415 04c6f1c7d920ea58fff702af95176615 381 SUPERFAMILY SSF53335 145 218 3.91E-34 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase ALX04_RS03415 04c6f1c7d920ea58fff702af95176615 381 SUPERFAMILY SSF53335 255 363 3.91E-34 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase ALX04_RS03415 04c6f1c7d920ea58fff702af95176615 381 Pfam PF01170 Putative RNA methylase family UPF0020 163 365 1.6E-54 T 28-03-2018 IPR000241 Putative RNA methylase domain KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 ALX04_RS03415 04c6f1c7d920ea58fff702af95176615 381 Pfam PF02926 THUMP domain 26 122 1.4E-8 T 28-03-2018 IPR004114 THUMP domain GO:0003723 ALX04_RS03415 04c6f1c7d920ea58fff702af95176615 381 ProSitePatterns PS01261 Uncharacterized protein family UPF0020 signature. 196 207 - T 28-03-2018 IPR000241 Putative RNA methylase domain KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 ALX04_RS03415 04c6f1c7d920ea58fff702af95176615 381 SMART SM00981 57 155 9.9E-8 T 28-03-2018 IPR004114 THUMP domain GO:0003723 ALX04_RS13550 a3f0e809edf97a26225ad34e6a5a3c71 288 TIGRFAM TIGR00154 ispE: 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase 2 284 7.4E-79 T 28-03-2018 IPR004424 4-diphosphocytidyl-2C-methyl-D-erythritol kinase GO:0016114|GO:0050515 KEGG: 00710+2.7.1.14|KEGG: 00900+2.7.1.148|MetaCyc: PWY-7560 ALX04_RS13550 a3f0e809edf97a26225ad34e6a5a3c71 288 Pfam PF00288 GHMP kinases N terminal domain 86 137 6.1E-9 T 28-03-2018 IPR006204 GHMP kinase N-terminal domain GO:0005524 ALX04_RS13550 a3f0e809edf97a26225ad34e6a5a3c71 288 Hamap MF_00061 Putative 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase [ispE]. 3 280 32.008 T 28-03-2018 IPR004424 4-diphosphocytidyl-2C-methyl-D-erythritol kinase GO:0016114|GO:0050515 KEGG: 00710+2.7.1.14|KEGG: 00900+2.7.1.148|MetaCyc: PWY-7560 ALX04_RS13550 a3f0e809edf97a26225ad34e6a5a3c71 288 SUPERFAMILY SSF54211 3 158 9.11E-39 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold ALX04_RS13550 a3f0e809edf97a26225ad34e6a5a3c71 288 Pfam PF08544 GHMP kinases C terminal 199 271 2.3E-10 T 28-03-2018 IPR013750 GHMP kinase, C-terminal domain ALX04_RS13550 a3f0e809edf97a26225ad34e6a5a3c71 288 Gene3D G3DSA:3.30.70.890 161 287 4.7E-28 T 28-03-2018 IPR013750 GHMP kinase, C-terminal domain ALX04_RS13550 a3f0e809edf97a26225ad34e6a5a3c71 288 SUPERFAMILY SSF55060 161 281 6.12E-31 T 28-03-2018 IPR013750 GHMP kinase, C-terminal domain ALX04_RS13550 a3f0e809edf97a26225ad34e6a5a3c71 288 Gene3D G3DSA:3.30.230.10 3 159 9.0E-39 T 28-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup ALX04_RS13550 a3f0e809edf97a26225ad34e6a5a3c71 288 PIRSF PIRSF010376 1 288 3.4E-86 T 28-03-2018 IPR004424 4-diphosphocytidyl-2C-methyl-D-erythritol kinase GO:0016114|GO:0050515 KEGG: 00710+2.7.1.14|KEGG: 00900+2.7.1.148|MetaCyc: PWY-7560 ALX04_RS02705 da175a9796720122a49c7cc5b22e4508 185 Hamap MF_00141 Elongation factor P [efp]. 1 185 51.458 T 28-03-2018 IPR011768 Translation elongation factor P GO:0003746|GO:0005737|GO:0006414 ALX04_RS02705 da175a9796720122a49c7cc5b22e4508 185 Pfam PF08207 Elongation factor P (EF-P) KOW-like domain 3 58 6.8E-27 T 28-03-2018 IPR013185 Translation elongation factor, KOW-like ALX04_RS02705 da175a9796720122a49c7cc5b22e4508 185 SMART SM01185 67 121 1.1E-30 T 28-03-2018 IPR001059 Translation elongation factor P/YeiP, central GO:0003746|GO:0006414 ALX04_RS02705 da175a9796720122a49c7cc5b22e4508 185 Gene3D G3DSA:2.30.30.30 2 61 3.9E-26 T 28-03-2018 IPR014722 Ribosomal protein L2 domain 2 ALX04_RS02705 da175a9796720122a49c7cc5b22e4508 185 ProSitePatterns PS01275 Elongation factor P signature. 150 169 - T 28-03-2018 IPR013852 Translation elongation factor P/YeiP, conserved site ALX04_RS02705 da175a9796720122a49c7cc5b22e4508 185 TIGRFAM TIGR00038 efp: translation elongation factor P 2 185 2.6E-82 T 28-03-2018 IPR011768 Translation elongation factor P GO:0003746|GO:0005737|GO:0006414 ALX04_RS02705 da175a9796720122a49c7cc5b22e4508 185 SUPERFAMILY SSF50249 65 129 1.27E-22 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold ALX04_RS02705 da175a9796720122a49c7cc5b22e4508 185 Gene3D G3DSA:2.40.50.140 64 127 1.2E-29 T 28-03-2018 ALX04_RS02705 da175a9796720122a49c7cc5b22e4508 185 SUPERFAMILY SSF50104 1 63 5.6E-21 T 28-03-2018 IPR008991 Translation protein SH3-like domain ALX04_RS02705 da175a9796720122a49c7cc5b22e4508 185 Gene3D G3DSA:2.40.50.140 129 184 3.2E-26 T 28-03-2018 ALX04_RS02705 da175a9796720122a49c7cc5b22e4508 185 SUPERFAMILY SSF50249 128 185 4.63E-18 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold ALX04_RS02705 da175a9796720122a49c7cc5b22e4508 185 SMART SM00841 129 184 1.4E-33 T 28-03-2018 IPR015365 Elongation factor P, C-terminal GO:0005737|GO:0043043 ALX04_RS02705 da175a9796720122a49c7cc5b22e4508 185 PIRSF PIRSF005901 1 185 1.0E-71 T 28-03-2018 IPR020599 Translation elongation factor P/YeiP ALX04_RS02705 da175a9796720122a49c7cc5b22e4508 185 Pfam PF09285 Elongation factor P, C-terminal 129 184 2.0E-25 T 28-03-2018 IPR015365 Elongation factor P, C-terminal GO:0005737|GO:0043043 ALX04_RS02705 da175a9796720122a49c7cc5b22e4508 185 Pfam PF01132 Elongation factor P (EF-P) OB domain 69 121 2.5E-26 T 28-03-2018 IPR001059 Translation elongation factor P/YeiP, central GO:0003746|GO:0006414 ALX04_RS12380 e783b199f5c8791186dd2e9f4f62b1b8 326 Pfam PF00356 Bacterial regulatory proteins, lacI family 4 49 7.3E-23 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 ALX04_RS12380 e783b199f5c8791186dd2e9f4f62b1b8 326 Gene3D G3DSA:3.40.50.2300 56 171 2.6E-31 T 28-03-2018 ALX04_RS12380 e783b199f5c8791186dd2e9f4f62b1b8 326 ProSitePatterns PS00356 LacI-type HTH domain signature. 5 23 - T 28-03-2018 ALX04_RS12380 e783b199f5c8791186dd2e9f4f62b1b8 326 SUPERFAMILY SSF47413 2 60 2.05E-18 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 ALX04_RS12380 e783b199f5c8791186dd2e9f4f62b1b8 326 SUPERFAMILY SSF53822 60 320 5.65E-64 T 28-03-2018 IPR028082 Periplasmic binding protein-like I ALX04_RS12380 e783b199f5c8791186dd2e9f4f62b1b8 326 Pfam PF13377 Periplasmic binding protein-like domain 165 323 3.3E-24 T 28-03-2018 ALX04_RS12380 e783b199f5c8791186dd2e9f4f62b1b8 326 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 14 24 1.6E-5 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 ALX04_RS12380 e783b199f5c8791186dd2e9f4f62b1b8 326 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 4 14 1.6E-5 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 ALX04_RS12380 e783b199f5c8791186dd2e9f4f62b1b8 326 SMART SM00354 2 72 1.8E-40 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 ALX04_RS12380 e783b199f5c8791186dd2e9f4f62b1b8 326 Gene3D G3DSA:1.10.260.40 4 55 4.0E-21 T 28-03-2018 ALX04_RS12380 e783b199f5c8791186dd2e9f4f62b1b8 326 Gene3D G3DSA:3.40.50.2300 172 305 6.5E-30 T 28-03-2018 ALX04_RS02225 d00dcb96ffff1a5e55d040e60b00d43c 214 Gene3D G3DSA:3.40.50.150 1 211 1.2E-29 T 28-03-2018 ALX04_RS02225 d00dcb96ffff1a5e55d040e60b00d43c 214 TIGRFAM TIGR00091 TIGR00091: tRNA (guanine-N(7)-)-methyltransferase 25 206 5.2E-49 T 28-03-2018 IPR003358 tRNA (guanine-N-7) methyltransferase, Trmb type GO:0006400|GO:0008176 Reactome: R-HSA-6782315 ALX04_RS02225 d00dcb96ffff1a5e55d040e60b00d43c 214 SUPERFAMILY SSF53335 18 202 2.62E-29 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase ALX04_RS02225 d00dcb96ffff1a5e55d040e60b00d43c 214 Hamap MF_01057 tRNA (guanine-N(7)-)-methyltransferase [trmB]. 1 212 28.069 T 28-03-2018 IPR003358 tRNA (guanine-N-7) methyltransferase, Trmb type GO:0006400|GO:0008176 Reactome: R-HSA-6782315 ALX04_RS02225 d00dcb96ffff1a5e55d040e60b00d43c 214 Pfam PF02390 Putative methyltransferase 39 202 7.1E-43 T 28-03-2018 IPR003358 tRNA (guanine-N-7) methyltransferase, Trmb type GO:0006400|GO:0008176 Reactome: R-HSA-6782315 ALX04_RS06320 8c23289976447879177e62111e1e30a5 376 Gene3D G3DSA:4.10.1060.10 2 49 2.2E-4 T 28-03-2018 ALX04_RS06320 8c23289976447879177e62111e1e30a5 376 SUPERFAMILY SSF56601 118 373 1.24E-41 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like ALX04_RS06320 8c23289976447879177e62111e1e30a5 376 Gene3D G3DSA:3.40.710.10 109 376 6.1E-25 T 28-03-2018 ALX04_RS06320 8c23289976447879177e62111e1e30a5 376 Pfam PF13354 Beta-lactamase enzyme family 150 347 8.6E-46 T 28-03-2018 ALX04_RS00085 e93262c6dfd1e480edf2bc9a4e812c4a 293 Pfam PF00849 RNA pseudouridylate synthase 85 236 4.0E-25 T 28-03-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 ALX04_RS00085 e93262c6dfd1e480edf2bc9a4e812c4a 293 SUPERFAMILY SSF55120 73 290 7.04E-61 T 28-03-2018 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 ALX04_RS00085 e93262c6dfd1e480edf2bc9a4e812c4a 293 Gene3D G3DSA:3.30.2350.10 76 293 6.3E-58 T 28-03-2018 ALX04_RS00085 e93262c6dfd1e480edf2bc9a4e812c4a 293 ProSitePatterns PS01129 Rlu family of pseudouridine synthase signature. 129 143 - T 28-03-2018 IPR006224 Pseudouridine synthase, RluC/RluD, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0009982 ALX04_RS00085 e93262c6dfd1e480edf2bc9a4e812c4a 293 TIGRFAM TIGR00005 rluA_subfam: pseudouridine synthase, RluA family 29 291 1.2E-61 T 28-03-2018 IPR006225 Pseudouridine synthase, RluC/RluD GO:0001522|GO:0003723|GO:0009451|GO:0009982 ALX04_RS05605 60c216170e68f5ea6c9a0800853c1635 89 Pfam PF00253 Ribosomal protein S14p/S29e 36 88 1.3E-24 T 28-03-2018 IPR001209 Ribosomal protein S14 GO:0003735|GO:0005622|GO:0005840|GO:0006412 ALX04_RS05605 60c216170e68f5ea6c9a0800853c1635 89 SUPERFAMILY SSF57716 2 89 2.0E-28 T 28-03-2018 ALX04_RS05605 60c216170e68f5ea6c9a0800853c1635 89 Hamap MF_00537 30S ribosomal protein S14 [rpsN]. 1 89 23.498 T 28-03-2018 IPR023036 Ribosomal protein S14, bacterial/plastid ALX04_RS05605 60c216170e68f5ea6c9a0800853c1635 89 Gene3D G3DSA:4.10.830.10 1 89 1.4E-32 T 28-03-2018 ALX04_RS10950 77e44e37e11563d3f23dda73c870aac9 648 Gene3D G3DSA:1.20.1250.20 255 474 2.4E-11 T 28-03-2018 ALX04_RS10950 77e44e37e11563d3f23dda73c870aac9 648 Gene3D G3DSA:1.20.1250.20 26 249 1.3E-8 T 28-03-2018 ALX04_RS10950 77e44e37e11563d3f23dda73c870aac9 648 TIGRFAM TIGR00830 PTBA: PTS system, glucose subfamily, IIA component 501 620 1.7E-34 T 28-03-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 ALX04_RS10950 77e44e37e11563d3f23dda73c870aac9 648 Pfam PF13347 MFS/sugar transport protein 26 464 4.8E-69 T 28-03-2018 ALX04_RS10950 77e44e37e11563d3f23dda73c870aac9 648 SUPERFAMILY SSF103473 35 471 2.62E-24 T 28-03-2018 IPR020846 Major facilitator superfamily domain ALX04_RS10950 77e44e37e11563d3f23dda73c870aac9 648 TIGRFAM TIGR00792 gph: sugar (Glycoside-Pentoside-Hexuronide) transporter 24 479 8.5E-129 T 28-03-2018 IPR001927 Sodium:galactoside symporter GO:0005215|GO:0006814|GO:0016020 ALX04_RS10950 77e44e37e11563d3f23dda73c870aac9 648 Pfam PF00358 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 500 621 1.1E-36 T 28-03-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 ALX04_RS10950 77e44e37e11563d3f23dda73c870aac9 648 SUPERFAMILY SSF51261 499 646 1.12E-42 T 28-03-2018 IPR011055 Duplicated hybrid motif ALX04_RS10950 77e44e37e11563d3f23dda73c870aac9 648 Gene3D G3DSA:2.70.70.10 490 647 2.6E-42 T 28-03-2018 ALX04_RS10950 77e44e37e11563d3f23dda73c870aac9 648 ProSitePatterns PS00872 Sodium:galactoside symporter family signature. 83 108 - T 28-03-2018 IPR018043 Sodium:galactoside symporter, conserved site GO:0005215|GO:0006814|GO:0016020 ALX04_RS03155 7322cfeafe60739bac0d797a7bf09f86 390 Pfam PF02353 Mycolic acid cyclopropane synthetase 104 369 2.6E-95 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase ALX04_RS03155 7322cfeafe60739bac0d797a7bf09f86 390 PIRSF PIRSF003085 7 389 2.9E-123 T 28-03-2018 IPR003333 Mycolic acid cyclopropane synthase GO:0008610 ALX04_RS03155 7322cfeafe60739bac0d797a7bf09f86 390 Gene3D G3DSA:3.40.50.150 101 374 5.7E-62 T 28-03-2018 ALX04_RS03155 7322cfeafe60739bac0d797a7bf09f86 390 SUPERFAMILY SSF53335 113 374 5.37E-75 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase ALX04_RS14815 d23ff8648b2b9540a0a9f174e8d6d00b 244 ProSitePatterns PS00211 ABC transporters family signature. 139 153 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 ALX04_RS14815 d23ff8648b2b9540a0a9f174e8d6d00b 244 PIRSF PIRSF039085 1 243 1.9E-114 T 28-03-2018 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 ALX04_RS14815 d23ff8648b2b9540a0a9f174e8d6d00b 244 SMART SM00382 28 215 7.5E-14 T 28-03-2018 IPR003593 AAA+ ATPase domain ALX04_RS14815 d23ff8648b2b9540a0a9f174e8d6d00b 244 SUPERFAMILY SSF52540 6 237 9.89E-80 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase ALX04_RS14815 d23ff8648b2b9540a0a9f174e8d6d00b 244 Pfam PF00005 ABC transporter 19 167 2.4E-36 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 ALX04_RS14815 d23ff8648b2b9540a0a9f174e8d6d00b 244 Gene3D G3DSA:3.40.50.300 2 243 6.8E-77 T 28-03-2018 ALX04_RS13695 1edf52791c03723c03b4d6a9f199943d 299 Pfam PF01435 Peptidase family M48 80 299 8.9E-31 T 28-03-2018 IPR001915 Peptidase M48 GO:0004222|GO:0006508 ALX04_RS13695 1edf52791c03723c03b4d6a9f199943d 299 Gene3D G3DSA:3.30.2010.10 71 162 4.0E-20 T 28-03-2018 ALX04_RS13695 1edf52791c03723c03b4d6a9f199943d 299 Hamap MF_00188 Protease HtpX [htpX]. 10 299 26.659 T 28-03-2018 IPR022919 Peptidase M48, protease HtpX, putative GO:0004222 ALX04_RS11230 1c310a22b624f30ac45bca749f547499 217 ProSitePatterns PS01054 Transaldolase signature 1. 24 32 - T 28-03-2018 IPR018225 Transaldolase, active site GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-71336 ALX04_RS11230 1c310a22b624f30ac45bca749f547499 217 Hamap MF_00494 Probable transaldolase [tal]. 1 214 47.253 T 28-03-2018 IPR022999 Transaldolase type 3B, putative GO:0004801 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723 ALX04_RS11230 1c310a22b624f30ac45bca749f547499 217 Gene3D G3DSA:3.20.20.70 1 217 7.2E-75 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 ALX04_RS11230 1c310a22b624f30ac45bca749f547499 217 ProSitePatterns PS00958 Transaldolase active site. 80 97 - T 28-03-2018 IPR018225 Transaldolase, active site GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-71336 ALX04_RS11230 1c310a22b624f30ac45bca749f547499 217 Pfam PF00923 Transaldolase/Fructose-6-phosphate aldolase 3 203 1.6E-58 T 28-03-2018 IPR001585 Transaldolase/Fructose-6-phosphate aldolase GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-71336 ALX04_RS11230 1c310a22b624f30ac45bca749f547499 217 SUPERFAMILY SSF51569 1 212 2.3E-77 T 28-03-2018 ALX04_RS11230 1c310a22b624f30ac45bca749f547499 217 TIGRFAM TIGR00875 fsa_talC_mipB: fructose-6-phosphate aldolase 1 211 1.0E-93 T 28-03-2018 IPR004731 Transaldolase type 3B/Fructose-6-phosphate aldolase GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723 ALX04_RS07610 aa16baead39393d02bf2ecc4e738027c 153 Pfam PF00582 Universal stress protein family 5 146 2.9E-28 T 28-03-2018 IPR006016 UspA GO:0006950 ALX04_RS07610 aa16baead39393d02bf2ecc4e738027c 153 PIRSF PIRSF006276 1 149 2.1E-17 T 28-03-2018 IPR006015 Universal stress protein A ALX04_RS07610 aa16baead39393d02bf2ecc4e738027c 153 SUPERFAMILY SSF52402 5 149 1.0E-30 T 28-03-2018 ALX04_RS07610 aa16baead39393d02bf2ecc4e738027c 153 Gene3D G3DSA:3.40.50.620 2 152 7.8E-31 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold ALX04_RS07610 aa16baead39393d02bf2ecc4e738027c 153 PRINTS PR01438 Universal stress protein signature 124 146 3.8E-15 T 28-03-2018 IPR006015 Universal stress protein A ALX04_RS07610 aa16baead39393d02bf2ecc4e738027c 153 PRINTS PR01438 Universal stress protein signature 106 118 3.8E-15 T 28-03-2018 IPR006015 Universal stress protein A ALX04_RS07610 aa16baead39393d02bf2ecc4e738027c 153 PRINTS PR01438 Universal stress protein signature 5 23 3.8E-15 T 28-03-2018 IPR006015 Universal stress protein A ALX04_RS13855 289cb59ec14f8e22c983dc0b7d416470 295 PIRSF PIRSF005261 1 292 5.8E-74 T 28-03-2018 IPR000397 Heat shock protein Hsp33 GO:0005737|GO:0006457|GO:0051082 ALX04_RS13855 289cb59ec14f8e22c983dc0b7d416470 295 Pfam PF01430 Hsp33 protein 3 280 1.3E-88 T 28-03-2018 IPR000397 Heat shock protein Hsp33 GO:0005737|GO:0006457|GO:0051082 ALX04_RS13855 289cb59ec14f8e22c983dc0b7d416470 295 Hamap MF_00117 33 kDa chaperonin [hslO]. 2 291 38.499 T 28-03-2018 IPR000397 Heat shock protein Hsp33 GO:0005737|GO:0006457|GO:0051082 ALX04_RS13855 289cb59ec14f8e22c983dc0b7d416470 295 Gene3D G3DSA:3.55.30.10 2 234 4.7E-76 T 28-03-2018 IPR016153 Heat shock protein Hsp33, N-terminal GO:0005737|GO:0006457|GO:0051082 ALX04_RS13855 289cb59ec14f8e22c983dc0b7d416470 295 Gene3D G3DSA:3.90.1280.10 235 288 7.6E-23 T 28-03-2018 IPR016154 Heat shock protein Hsp33, C-terminal GO:0005737|GO:0006457|GO:0051082 ALX04_RS13855 289cb59ec14f8e22c983dc0b7d416470 295 SUPERFAMILY SSF118352 231 289 6.67E-20 T 28-03-2018 IPR016154 Heat shock protein Hsp33, C-terminal GO:0005737|GO:0006457|GO:0051082 ALX04_RS13855 289cb59ec14f8e22c983dc0b7d416470 295 SUPERFAMILY SSF64397 3 241 6.93E-74 T 28-03-2018 IPR016153 Heat shock protein Hsp33, N-terminal GO:0005737|GO:0006457|GO:0051082 ALX04_RS00040 ba8ec40bbcce4ab965c01924742a1419 157 Gene3D G3DSA:1.10.10.10 2 155 8.9E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS00040 ba8ec40bbcce4ab965c01924742a1419 157 SUPERFAMILY SSF46785 45 154 1.89E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS00040 ba8ec40bbcce4ab965c01924742a1419 157 Pfam PF01047 MarR family 51 102 1.1E-7 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 ALX04_RS00040 ba8ec40bbcce4ab965c01924742a1419 157 SMART SM00347 40 142 3.2E-4 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 ALX04_RS13785 b2c25dd47de0f23641a34c49852b4ad1 340 SUPERFAMILY SSF53671 4 331 4.84E-94 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 ALX04_RS13785 b2c25dd47de0f23641a34c49852b4ad1 340 TIGRFAM TIGR00658 orni_carb_tr: ornithine carbamoyltransferase 8 329 3.2E-117 T 28-03-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 ALX04_RS13785 b2c25dd47de0f23641a34c49852b4ad1 340 Pfam PF00185 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain 154 327 2.0E-48 T 28-03-2018 IPR006131 Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain GO:0006520|GO:0016597|GO:0016743 ALX04_RS13785 b2c25dd47de0f23641a34c49852b4ad1 340 PRINTS PR00102 Ornithine carbamoyltransferase signature 228 238 6.9E-26 T 28-03-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 ALX04_RS13785 b2c25dd47de0f23641a34c49852b4ad1 340 PRINTS PR00102 Ornithine carbamoyltransferase signature 84 97 6.9E-26 T 28-03-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 ALX04_RS13785 b2c25dd47de0f23641a34c49852b4ad1 340 PRINTS PR00102 Ornithine carbamoyltransferase signature 51 65 6.9E-26 T 28-03-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 ALX04_RS13785 b2c25dd47de0f23641a34c49852b4ad1 340 PRINTS PR00102 Ornithine carbamoyltransferase signature 308 319 6.9E-26 T 28-03-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 ALX04_RS13785 b2c25dd47de0f23641a34c49852b4ad1 340 PRINTS PR00102 Ornithine carbamoyltransferase signature 124 138 6.9E-26 T 28-03-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 ALX04_RS13785 b2c25dd47de0f23641a34c49852b4ad1 340 Gene3D G3DSA:3.40.50.1370 1 147 9.7E-53 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 ALX04_RS13785 b2c25dd47de0f23641a34c49852b4ad1 340 ProSitePatterns PS00097 Aspartate and ornithine carbamoyltransferases signature. 53 60 - T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 ALX04_RS13785 b2c25dd47de0f23641a34c49852b4ad1 340 Hamap MF_01109 Ornithine carbamoyltransferase, catabolic [argI]. 7 330 78.19 T 28-03-2018 IPR024904 Ornithine carbamoyltransferase GO:0004585|GO:0006591 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400 ALX04_RS13785 b2c25dd47de0f23641a34c49852b4ad1 340 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 135 146 7.2E-23 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 ALX04_RS13785 b2c25dd47de0f23641a34c49852b4ad1 340 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 53 72 7.2E-23 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 ALX04_RS13785 b2c25dd47de0f23641a34c49852b4ad1 340 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 265 274 7.2E-23 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 ALX04_RS13785 b2c25dd47de0f23641a34c49852b4ad1 340 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 294 317 7.2E-23 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 ALX04_RS13785 b2c25dd47de0f23641a34c49852b4ad1 340 Gene3D G3DSA:3.40.50.1370 148 316 2.9E-49 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 ALX04_RS13785 b2c25dd47de0f23641a34c49852b4ad1 340 Pfam PF02729 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain 8 148 1.2E-42 T 28-03-2018 IPR006132 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding GO:0006520|GO:0016743 ALX04_RS02905 bd4874fa07af85973b88dd337f051e7d 246 PIRSF PIRSF000386 1 246 5.8E-100 T 28-03-2018 IPR002649 tRNA (guanine-N1-)-methyltransferase, bacteria GO:0008033|GO:0052906 KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 ALX04_RS02905 bd4874fa07af85973b88dd337f051e7d 246 TIGRFAM TIGR00088 trmD: tRNA (guanine(37)-N(1))-methyltransferase 1 226 3.4E-93 T 28-03-2018 IPR002649 tRNA (guanine-N1-)-methyltransferase, bacteria GO:0008033|GO:0052906 KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 ALX04_RS02905 bd4874fa07af85973b88dd337f051e7d 246 Gene3D G3DSA:3.40.1280.10 1 168 1.2E-74 T 28-03-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal ALX04_RS02905 bd4874fa07af85973b88dd337f051e7d 246 SUPERFAMILY SSF75217 1 242 8.5E-100 T 28-03-2018 IPR029028 Alpha/beta knot methyltransferases ALX04_RS02905 bd4874fa07af85973b88dd337f051e7d 246 Hamap MF_00605 tRNA (guanine-N(1)-)-methyltransferase [trmD]. 1 246 109.14 T 28-03-2018 IPR002649 tRNA (guanine-N1-)-methyltransferase, bacteria GO:0008033|GO:0052906 KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 ALX04_RS02905 bd4874fa07af85973b88dd337f051e7d 246 Pfam PF01746 tRNA (Guanine-1)-methyltransferase 24 220 3.2E-68 T 28-03-2018 IPR016009 tRNA methyltransferase TRMD/TRM10-type domain KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 ALX04_RS02905 bd4874fa07af85973b88dd337f051e7d 246 Gene3D G3DSA:1.10.1270.20 169 246 7.6E-34 T 28-03-2018 ALX04_RS12360 bf6a4651d4b2ea924dcc8bc120139ea7 288 Gene3D G3DSA:3.30.420.40 2 114 3.8E-14 T 28-03-2018 ALX04_RS12360 bf6a4651d4b2ea924dcc8bc120139ea7 288 ProSitePatterns PS01125 ROK family signature. 129 154 - T 28-03-2018 IPR000600 ROK family Reactome: R-HSA-4085001 ALX04_RS12360 bf6a4651d4b2ea924dcc8bc120139ea7 288 Pfam PF00480 ROK family 4 283 2.0E-90 T 28-03-2018 IPR000600 ROK family Reactome: R-HSA-4085001 ALX04_RS12360 bf6a4651d4b2ea924dcc8bc120139ea7 288 SUPERFAMILY SSF53067 1 286 1.78E-46 T 28-03-2018 ALX04_RS12360 bf6a4651d4b2ea924dcc8bc120139ea7 288 Gene3D G3DSA:3.30.420.40 115 288 4.0E-36 T 28-03-2018 ALX04_RS12520 201978fd9cb4ddf8ff0fd15d6c17ae43 156 ProSitePatterns PS00829 Prokaryotic transcription elongation factors signature 1. 19 49 - T 28-03-2018 IPR018151 Transcription elongation factor, GreA/GreB, conserved site GO:0003677|GO:0032784 ALX04_RS12520 201978fd9cb4ddf8ff0fd15d6c17ae43 156 Pfam PF03449 Transcription elongation factor, N-terminal 7 75 1.6E-21 T 28-03-2018 IPR022691 Transcription elongation factor, GreA/GreB, N-terminal GO:0003677|GO:0032784 ALX04_RS12520 201978fd9cb4ddf8ff0fd15d6c17ae43 156 Pfam PF01272 Transcription elongation factor, GreA/GreB, C-term 81 154 4.3E-25 T 28-03-2018 IPR001437 Transcription elongation factor, GreA/GreB, C-terminal GO:0003677|GO:0032784 ALX04_RS12520 201978fd9cb4ddf8ff0fd15d6c17ae43 156 PIRSF PIRSF006092 1 156 2.4E-52 T 28-03-2018 IPR023459 Transcription elongation factor GreA/GreB family GO:0070063 ALX04_RS12520 201978fd9cb4ddf8ff0fd15d6c17ae43 156 SUPERFAMILY SSF46557 7 77 1.2E-20 T 28-03-2018 IPR022691 Transcription elongation factor, GreA/GreB, N-terminal GO:0003677|GO:0032784 ALX04_RS12520 201978fd9cb4ddf8ff0fd15d6c17ae43 156 Gene3D G3DSA:3.10.50.30 76 155 1.2E-23 T 28-03-2018 IPR001437 Transcription elongation factor, GreA/GreB, C-terminal GO:0003677|GO:0032784 ALX04_RS12520 201978fd9cb4ddf8ff0fd15d6c17ae43 156 Gene3D G3DSA:1.10.287.180 6 75 2.6E-22 T 28-03-2018 ALX04_RS12520 201978fd9cb4ddf8ff0fd15d6c17ae43 156 SUPERFAMILY SSF54534 79 153 3.53E-19 T 28-03-2018 ALX04_RS12520 201978fd9cb4ddf8ff0fd15d6c17ae43 156 Hamap MF_00105 Transcription elongation factor GreA [greA]. 4 154 29.156 T 28-03-2018 IPR028624 Transcription elongation factor GreA/GreB GO:0003677|GO:0032784|GO:0070063 ALX04_RS14115 c4ff5cf5c1152f8ea1ed079b23355fc2 284 PIRSF PIRSF032442 61 284 1.1E-90 T 28-03-2018 IPR016997 Uncharacterised conserved protein UCP032442 ALX04_RS14115 c4ff5cf5c1152f8ea1ed079b23355fc2 284 Pfam PF13529 Peptidase_C39 like family 126 258 4.8E-27 T 28-03-2018 ALX04_RS14115 c4ff5cf5c1152f8ea1ed079b23355fc2 284 Gene3D G3DSA:3.90.70.10 136 283 8.2E-19 T 28-03-2018 ALX04_RS01275 26c35faf9db67923ca43f265537b0084 243 Gene3D G3DSA:3.90.1720.10 121 238 2.8E-29 T 28-03-2018 ALX04_RS01275 26c35faf9db67923ca43f265537b0084 243 SUPERFAMILY SSF54001 120 226 6.38E-32 T 28-03-2018 ALX04_RS01275 26c35faf9db67923ca43f265537b0084 243 Pfam PF00877 NlpC/P60 family 135 226 1.4E-24 T 28-03-2018 IPR000064 Endopeptidase, NLPC/P60 domain ALX04_RS01275 26c35faf9db67923ca43f265537b0084 243 Gene3D G3DSA:2.30.30.170 31 120 7.3E-5 T 28-03-2018 ALX04_RS11275 e8a702013af0ffe9d63eee242f611dcc 156 SUPERFAMILY SSF55804 8 156 2.22E-36 T 28-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 ALX04_RS11275 e8a702013af0ffe9d63eee242f611dcc 156 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 11 156 3.5E-33 T 28-03-2018 IPR002178 PTS EIIA type-2 domain ALX04_RS11275 e8a702013af0ffe9d63eee242f611dcc 156 Gene3D G3DSA:3.40.930.10 6 156 3.7E-32 T 28-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 ALX04_RS09895 5c23e9985b62b2e3ec1175962a6bf08e 296 SUPERFAMILY SSF110849 32 126 3.92E-28 T 28-03-2018 IPR003115 ParB/Sulfiredoxin ALX04_RS09895 5c23e9985b62b2e3ec1175962a6bf08e 296 Gene3D G3DSA:1.10.10.730 125 172 8.8E-19 T 28-03-2018 ALX04_RS09895 5c23e9985b62b2e3ec1175962a6bf08e 296 Pfam PF02195 ParB-like nuclease domain 34 123 3.3E-25 T 28-03-2018 IPR003115 ParB/Sulfiredoxin ALX04_RS09895 5c23e9985b62b2e3ec1175962a6bf08e 296 SMART SM00470 32 124 2.6E-32 T 28-03-2018 IPR003115 ParB/Sulfiredoxin ALX04_RS09895 5c23e9985b62b2e3ec1175962a6bf08e 296 SUPERFAMILY SSF109709 116 226 2.62E-33 T 28-03-2018 ALX04_RS09895 5c23e9985b62b2e3ec1175962a6bf08e 296 Gene3D G3DSA:3.90.1530.10 20 124 8.1E-36 T 28-03-2018 ALX04_RS09895 5c23e9985b62b2e3ec1175962a6bf08e 296 TIGRFAM TIGR00180 parB_part: ParB/RepB/Spo0J family partition protein 30 208 1.6E-60 T 28-03-2018 IPR004437 ParB/RepB/Spo0J partition protein family GO:0003677 ALX04_RS09895 5c23e9985b62b2e3ec1175962a6bf08e 296 Pfam PF08535 KorB domain 147 205 5.9E-5 T 28-03-2018 IPR013741 Repressor KorB domain ALX04_RS02380 19d0f56334fccbc9b8f6ce3728b41704 569 Pfam PF01609 Transposase DDE domain 257 508 8.6E-33 T 28-03-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 ALX04_RS02380 19d0f56334fccbc9b8f6ce3728b41704 569 Gene3D G3DSA:3.90.350.10 282 491 5.8E-8 T 28-03-2018 IPR014736 Transposase, Tn5-like, core ALX04_RS02380 19d0f56334fccbc9b8f6ce3728b41704 569 Pfam PF05598 Transposase domain (DUF772) 45 101 1.4E-11 T 28-03-2018 IPR008490 Transposase InsH, N-terminal ALX04_RS14185 74316f201aba0e6cca5318736f6176eb 320 Pfam PF03547 Membrane transport protein 168 310 4.2E-17 T 28-03-2018 IPR004776 Membrane transport protein GO:0016021|GO:0055085 ALX04_RS14185 74316f201aba0e6cca5318736f6176eb 320 Pfam PF03547 Membrane transport protein 12 158 7.0E-19 T 28-03-2018 IPR004776 Membrane transport protein GO:0016021|GO:0055085 ALX04_RS00985 ae467a4fc4951a308838a66b1412cee9 448 SMART SM00839 205 446 1.2E-86 T 28-03-2018 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 ALX04_RS00985 ae467a4fc4951a308838a66b1412cee9 448 SUPERFAMILY SSF53223 7 197 1.22E-74 T 28-03-2018 ALX04_RS00985 ae467a4fc4951a308838a66b1412cee9 448 Pfam PF00208 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase 203 446 1.6E-86 T 28-03-2018 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 ALX04_RS00985 ae467a4fc4951a308838a66b1412cee9 448 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 194 216 1.5E-32 T 28-03-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 ALX04_RS00985 ae467a4fc4951a308838a66b1412cee9 448 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 115 129 1.5E-32 T 28-03-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 ALX04_RS00985 ae467a4fc4951a308838a66b1412cee9 448 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 236 256 1.5E-32 T 28-03-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 ALX04_RS00985 ae467a4fc4951a308838a66b1412cee9 448 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 372 383 1.5E-32 T 28-03-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 ALX04_RS00985 ae467a4fc4951a308838a66b1412cee9 448 SUPERFAMILY SSF51735 203 447 1.15E-69 T 28-03-2018 IPR016040 NAD(P)-binding domain ALX04_RS00985 ae467a4fc4951a308838a66b1412cee9 448 Pfam PF02812 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain 58 186 4.0E-51 T 28-03-2018 IPR006097 Glutamate/phenylalanine/leucine/valine dehydrogenase, dimerisation domain GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 ALX04_RS00985 ae467a4fc4951a308838a66b1412cee9 448 ProSitePatterns PS00074 Glu / Leu / Phe / Val dehydrogenases active site. 123 136 - T 28-03-2018 IPR033524 Leu/Phe/Val dehydrogenases active site Reactome: R-HSA-2151201|Reactome: R-HSA-70614 ALX04_RS00985 ae467a4fc4951a308838a66b1412cee9 448 PIRSF PIRSF000185 23 448 2.4E-120 T 28-03-2018 IPR014362 Glutamate dehydrogenase GO:0016639|GO:0055114 ALX04_RS00985 ae467a4fc4951a308838a66b1412cee9 448 Gene3D G3DSA:1.10.285.10 7 61 4.3E-6 T 28-03-2018 ALX04_RS00985 ae467a4fc4951a308838a66b1412cee9 448 Gene3D G3DSA:1.10.285.10 374 448 2.3E-29 T 28-03-2018 ALX04_RS00985 ae467a4fc4951a308838a66b1412cee9 448 Gene3D G3DSA:3.40.50.720 210 373 3.5E-43 T 28-03-2018 ALX04_RS00985 ae467a4fc4951a308838a66b1412cee9 448 Gene3D G3DSA:3.40.50.10860 62 190 3.2E-56 T 28-03-2018 ALX04_RS14260 d0f36495245a07826b5170850db73652 255 SUPERFAMILY SSF55315 10 84 6.36E-18 T 28-03-2018 IPR029064 50S ribosomal protein L30e-like ALX04_RS14260 d0f36495245a07826b5170850db73652 255 Gene3D G3DSA:3.30.1330.30 1 83 2.2E-17 T 28-03-2018 IPR029064 50S ribosomal protein L30e-like ALX04_RS14260 d0f36495245a07826b5170850db73652 255 SMART SM00967 13 88 3.1E-20 T 28-03-2018 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 Reactome: R-HSA-6793080 ALX04_RS14260 d0f36495245a07826b5170850db73652 255 Pfam PF00588 SpoU rRNA Methylase family 105 244 2.4E-39 T 28-03-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 ALX04_RS14260 d0f36495245a07826b5170850db73652 255 TIGRFAM TIGR00186 rRNA_methyl_3: RNA methyltransferase, TrmH family, group 3 12 248 4.5E-75 T 28-03-2018 IPR004441 RNA methyltransferase TrmH family GO:0006396|GO:0008173 Reactome: R-HSA-6793080 ALX04_RS14260 d0f36495245a07826b5170850db73652 255 Gene3D G3DSA:3.40.1280.10 86 252 1.2E-42 T 28-03-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal ALX04_RS14260 d0f36495245a07826b5170850db73652 255 SUPERFAMILY SSF75217 76 250 1.11E-45 T 28-03-2018 IPR029028 Alpha/beta knot methyltransferases ALX04_RS14260 d0f36495245a07826b5170850db73652 255 Pfam PF08032 RNA 2'-O ribose methyltransferase substrate binding 13 87 1.9E-19 T 28-03-2018 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 Reactome: R-HSA-6793080 ALX04_RS00910 27abfea3ecd71c2cacf683b9e9a87c07 438 Pfam PF02378 Phosphotransferase system, EIIC 31 356 1.3E-17 T 28-03-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 ALX04_RS00910 27abfea3ecd71c2cacf683b9e9a87c07 438 PIRSF PIRSF006351 5 436 5.0E-68 T 28-03-2018 IPR004796 Phosphotransferase system, cellobiose-type IIC component GO:0008982|GO:0009401|GO:0016021 ALX04_RS14855 23b7b8b11565e006460a5ac11a03f63b 254 ProSitePatterns PS00726 AP endonucleases family 1 signature 1. 28 37 - T 28-03-2018 IPR020847 AP endonuclease 1, binding site GO:0003677|GO:0004519|GO:0005622|GO:0006281 ALX04_RS14855 23b7b8b11565e006460a5ac11a03f63b 254 ProSitePatterns PS00727 AP endonucleases family 1 signature 2. 184 200 - T 28-03-2018 IPR020848 AP endonuclease 1, conserved site GO:0003677|GO:0004519|GO:0005622|GO:0006281 Reactome: R-HSA-110357|Reactome: R-HSA-110362|Reactome: R-HSA-110373|Reactome: R-HSA-5651801|Reactome: R-HSA-73930|Reactome: R-HSA-73933 ALX04_RS14855 23b7b8b11565e006460a5ac11a03f63b 254 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 5 242 1.6E-18 T 28-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase ALX04_RS14855 23b7b8b11565e006460a5ac11a03f63b 254 TIGRFAM TIGR00195 exoDNase_III: exodeoxyribonuclease III 1 248 2.1E-88 T 28-03-2018 ALX04_RS14855 23b7b8b11565e006460a5ac11a03f63b 254 TIGRFAM TIGR00633 xth: exodeoxyribonuclease III (xth) 1 249 1.3E-91 T 28-03-2018 IPR004808 AP endonuclease 1 GO:0004518|GO:0006281 ALX04_RS14855 23b7b8b11565e006460a5ac11a03f63b 254 SUPERFAMILY SSF56219 2 249 1.7E-76 T 28-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase ALX04_RS14855 23b7b8b11565e006460a5ac11a03f63b 254 Gene3D G3DSA:3.60.10.10 1 254 1.8E-53 T 28-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase ALX04_RS07510 23c9d5b2d7107e9a68898500ee3623b1 307 Gene3D G3DSA:3.40.50.1820 59 307 5.3E-38 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold ALX04_RS07510 23c9d5b2d7107e9a68898500ee3623b1 307 Pfam PF12146 Serine aminopeptidase, S33 85 197 2.2E-8 T 28-03-2018 IPR022742 Serine aminopeptidase, S33 ALX04_RS07510 23c9d5b2d7107e9a68898500ee3623b1 307 SUPERFAMILY SSF53474 37 306 3.6E-39 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold ALX04_RS01540 90ce0a844fb9f1028ce8eefdaf7110b3 180 Gene3D G3DSA:3.40.50.2020 1 171 2.7E-28 T 28-03-2018 ALX04_RS01540 90ce0a844fb9f1028ce8eefdaf7110b3 180 SUPERFAMILY SSF53271 27 162 8.39E-25 T 28-03-2018 IPR029057 Phosphoribosyltransferase-like ALX04_RS01540 90ce0a844fb9f1028ce8eefdaf7110b3 180 Pfam PF00156 Phosphoribosyl transferase domain 41 169 3.4E-18 T 28-03-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 ALX04_RS11585 2195d66edaa3b71f9d2172e9e6d923af 374 Pfam PF02463 RecF/RecN/SMC N terminal domain 2 341 5.1E-15 T 28-03-2018 IPR003395 RecF/RecN/SMC, N-terminal ALX04_RS11585 2195d66edaa3b71f9d2172e9e6d923af 374 SUPERFAMILY SSF52540 244 352 1.07E-45 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase ALX04_RS11585 2195d66edaa3b71f9d2172e9e6d923af 374 SUPERFAMILY SSF52540 1 217 1.07E-45 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase ALX04_RS11585 2195d66edaa3b71f9d2172e9e6d923af 374 ProSitePatterns PS00618 RecF protein signature 2. 312 330 - T 28-03-2018 IPR018078 DNA-binding, RecF, conserved site GO:0003697|GO:0005524|GO:0006281 ALX04_RS11585 2195d66edaa3b71f9d2172e9e6d923af 374 TIGRFAM TIGR00611 recf: DNA replication and repair protein RecF 1 366 1.5E-125 T 28-03-2018 IPR001238 DNA-binding, RecF GO:0003697|GO:0005524|GO:0006281 ALX04_RS11585 2195d66edaa3b71f9d2172e9e6d923af 374 Gene3D G3DSA:3.40.50.300 1 371 1.8E-35 T 28-03-2018 ALX04_RS11585 2195d66edaa3b71f9d2172e9e6d923af 374 Hamap MF_00365 DNA replication and repair protein RecF [recF]. 1 374 103.993 T 28-03-2018 IPR001238 DNA-binding, RecF GO:0003697|GO:0005524|GO:0006281 ALX04_RS11585 2195d66edaa3b71f9d2172e9e6d923af 374 ProSitePatterns PS00617 RecF protein signature 1. 116 136 - T 28-03-2018 IPR018078 DNA-binding, RecF, conserved site GO:0003697|GO:0005524|GO:0006281 ALX04_RS14245 8bc292638d7e0218d832eb2a91b2031b 496 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 12 23 - T 28-03-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 ALX04_RS14245 8bc292638d7e0218d832eb2a91b2031b 496 Pfam PF00749 tRNA synthetases class I (E and Q), catalytic domain 5 330 2.4E-114 T 28-03-2018 IPR020058 Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domain GO:0005524|GO:0016876|GO:0043039 ALX04_RS14245 8bc292638d7e0218d832eb2a91b2031b 496 SUPERFAMILY SSF52374 5 323 7.78E-105 T 28-03-2018 ALX04_RS14245 8bc292638d7e0218d832eb2a91b2031b 496 SUPERFAMILY SSF48163 306 489 6.67E-44 T 28-03-2018 IPR008925 Aminoacyl-tRNA synthetase, class I, anticodon-binding GO:0000049 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 ALX04_RS14245 8bc292638d7e0218d832eb2a91b2031b 496 PRINTS PR00987 Glutamyl-tRNA synthetase signature 216 224 1.8E-28 T 28-03-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 ALX04_RS14245 8bc292638d7e0218d832eb2a91b2031b 496 PRINTS PR00987 Glutamyl-tRNA synthetase signature 9 21 1.8E-28 T 28-03-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 ALX04_RS14245 8bc292638d7e0218d832eb2a91b2031b 496 PRINTS PR00987 Glutamyl-tRNA synthetase signature 200 210 1.8E-28 T 28-03-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 ALX04_RS14245 8bc292638d7e0218d832eb2a91b2031b 496 PRINTS PR00987 Glutamyl-tRNA synthetase signature 38 51 1.8E-28 T 28-03-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 ALX04_RS14245 8bc292638d7e0218d832eb2a91b2031b 496 PRINTS PR00987 Glutamyl-tRNA synthetase signature 23 34 1.8E-28 T 28-03-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 ALX04_RS14245 8bc292638d7e0218d832eb2a91b2031b 496 Gene3D G3DSA:3.40.50.620 1 148 1.2E-39 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold ALX04_RS14245 8bc292638d7e0218d832eb2a91b2031b 496 Gene3D G3DSA:3.40.50.620 149 252 6.5E-26 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold ALX04_RS14245 8bc292638d7e0218d832eb2a91b2031b 496 Gene3D G3DSA:1.10.10.350 393 492 1.6E-25 T 28-03-2018 IPR020751 Aminoacyl-tRNA synthetase, class I, anticodon-binding domain, subdomain 2 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 ALX04_RS14245 8bc292638d7e0218d832eb2a91b2031b 496 Gene3D G3DSA:1.10.1160.10 254 340 8.7E-28 T 28-03-2018 IPR020061 Glutamyl/glutaminyl-tRNA synthetase, class Ib, alpha-bundle domain GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0006418 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188 ALX04_RS14245 8bc292638d7e0218d832eb2a91b2031b 496 Hamap MF_00022 Glutamate--tRNA ligase [gltX]. 5 491 31.867 T 28-03-2018 IPR004527 Glutamate-tRNA ligase, bacterial/mitochondrial GO:0000166|GO:0004818|GO:0005524|GO:0005737|GO:0006424 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 ALX04_RS14245 8bc292638d7e0218d832eb2a91b2031b 496 TIGRFAM TIGR00464 gltX_bact: glutamate--tRNA ligase 5 490 9.2E-170 T 28-03-2018 IPR004527 Glutamate-tRNA ligase, bacterial/mitochondrial GO:0000166|GO:0004818|GO:0005524|GO:0005737|GO:0006424 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 ALX04_RS08630 38d5c1c0aa2bdfdb9b3cec8265834ba7 294 PIRSF PIRSF000097 1 115 2.2E-36 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 ALX04_RS08630 38d5c1c0aa2bdfdb9b3cec8265834ba7 294 PIRSF PIRSF000097 114 280 1.6E-45 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 ALX04_RS08630 38d5c1c0aa2bdfdb9b3cec8265834ba7 294 PRINTS PR00069 Aldo-keto reductase signature 38 62 6.0E-45 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 ALX04_RS08630 38d5c1c0aa2bdfdb9b3cec8265834ba7 294 PRINTS PR00069 Aldo-keto reductase signature 157 186 6.0E-45 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 ALX04_RS08630 38d5c1c0aa2bdfdb9b3cec8265834ba7 294 PRINTS PR00069 Aldo-keto reductase signature 196 220 6.0E-45 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 ALX04_RS08630 38d5c1c0aa2bdfdb9b3cec8265834ba7 294 PRINTS PR00069 Aldo-keto reductase signature 94 112 6.0E-45 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 ALX04_RS08630 38d5c1c0aa2bdfdb9b3cec8265834ba7 294 PRINTS PR00069 Aldo-keto reductase signature 123 140 6.0E-45 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 ALX04_RS08630 38d5c1c0aa2bdfdb9b3cec8265834ba7 294 ProSitePatterns PS00062 Aldo/keto reductase family signature 2. 123 140 - T 28-03-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 ALX04_RS08630 38d5c1c0aa2bdfdb9b3cec8265834ba7 294 ProSitePatterns PS00063 Aldo/keto reductase family putative active site signature. 229 244 - T 28-03-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 ALX04_RS08630 38d5c1c0aa2bdfdb9b3cec8265834ba7 294 Pfam PF00248 Aldo/keto reductase family 26 261 3.7E-49 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain ALX04_RS08630 38d5c1c0aa2bdfdb9b3cec8265834ba7 294 SUPERFAMILY SSF51430 1 269 5.63E-89 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain ALX04_RS08630 38d5c1c0aa2bdfdb9b3cec8265834ba7 294 Gene3D G3DSA:3.20.20.100 2 277 1.1E-92 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain ALX04_RS06040 b83911b69d7b610c9d268750edba36a9 380 SUPERFAMILY SSF51713 6 370 7.32E-151 T 28-03-2018 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 ALX04_RS06040 b83911b69d7b610c9d268750edba36a9 380 TIGRFAM TIGR00430 Q_tRNA_tgt: tRNA-guanine transglycosylase 7 373 2.9E-169 T 28-03-2018 IPR004803 tRNA-guanine transglycosylase GO:0008479|GO:0101030 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 ALX04_RS06040 b83911b69d7b610c9d268750edba36a9 380 Hamap MF_00168 Queuine tRNA-ribosyltransferase [tgt]. 5 369 54.508 T 28-03-2018 IPR004803 tRNA-guanine transglycosylase GO:0008479|GO:0101030 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 ALX04_RS06040 b83911b69d7b610c9d268750edba36a9 380 Gene3D G3DSA:3.20.20.105 1 375 5.9E-150 T 28-03-2018 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 ALX04_RS06040 b83911b69d7b610c9d268750edba36a9 380 Pfam PF01702 Queuine tRNA-ribosyltransferase 133 366 1.0E-85 T 28-03-2018 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 ALX04_RS06040 b83911b69d7b610c9d268750edba36a9 380 TIGRFAM TIGR00449 tgt_general: tRNA-guanine family transglycosylase 7 373 8.9E-160 T 28-03-2018 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 ALX04_RS07525 b890aa8d8fc8b619a55a1d0588e5b0a5 283 Gene3D G3DSA:3.40.50.150 4 273 1.6E-4 T 28-03-2018 ALX04_RS07525 b890aa8d8fc8b619a55a1d0588e5b0a5 283 SUPERFAMILY SSF53335 104 226 4.86E-5 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase ALX04_RS04830 9bbfecb0b06ded671e5fa69453c0c612 124 TIGRFAM TIGR01563 gp16_SPP1: putative phage head-tail adaptor 19 118 3.6E-10 T 28-03-2018 IPR008767 Bacteriophage SPP1, head-tail adaptor ALX04_RS04830 9bbfecb0b06ded671e5fa69453c0c612 124 Pfam PF05521 Phage head-tail joining protein 20 105 2.0E-9 T 28-03-2018 IPR008767 Bacteriophage SPP1, head-tail adaptor ALX04_RS09520 e8e5649962ac1a3db3d87b80887c32c8 120 Pfam PF01638 HxlR-like helix-turn-helix 16 104 3.7E-35 T 28-03-2018 IPR002577 Helix-turn-helix, HxlR type ALX04_RS09520 e8e5649962ac1a3db3d87b80887c32c8 120 SUPERFAMILY SSF46785 3 110 2.14E-31 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS09520 e8e5649962ac1a3db3d87b80887c32c8 120 Gene3D G3DSA:1.10.10.10 14 113 9.8E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS05120 ef26a1ba0956137fec10f1a66b46fb94 322 SUPERFAMILY SSF53448 3 226 8.04E-43 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases ALX04_RS05120 ef26a1ba0956137fec10f1a66b46fb94 322 Gene3D G3DSA:3.90.550.10 2 290 2.8E-35 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases ALX04_RS05120 ef26a1ba0956137fec10f1a66b46fb94 322 Pfam PF00535 Glycosyl transferase family 2 4 167 8.5E-22 T 28-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 ALX04_RS03765 48ed2b83768ea57fcd522faf4a1e7faf 292 Pfam PF01263 Aldose 1-epimerase 2 251 3.3E-31 T 28-03-2018 IPR008183 Aldose 1-/Glucose-6-phosphate 1-epimerase GO:0005975|GO:0016853 ALX04_RS03765 48ed2b83768ea57fcd522faf4a1e7faf 292 Gene3D G3DSA:2.70.98.10 1 292 2.7E-64 T 28-03-2018 IPR014718 Glycoside hydrolase-type carbohydrate-binding GO:0030246 ALX04_RS03765 48ed2b83768ea57fcd522faf4a1e7faf 292 SUPERFAMILY SSF74650 2 291 4.58E-56 T 28-03-2018 IPR011013 Galactose mutarotase-like domain GO:0003824|GO:0005975|GO:0030246 ALX04_RS14845 3ed69a14840c701d6ff7143fae3eca90 171 SUPERFAMILY SSF55729 8 151 1.1E-27 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase ALX04_RS14845 3ed69a14840c701d6ff7143fae3eca90 171 Gene3D G3DSA:3.40.630.30 1 96 9.6E-11 T 28-03-2018 ALX04_RS14845 3ed69a14840c701d6ff7143fae3eca90 171 Pfam PF00583 Acetyltransferase (GNAT) family 48 144 6.0E-15 T 28-03-2018 IPR000182 GNAT domain GO:0008080 ALX04_RS14845 3ed69a14840c701d6ff7143fae3eca90 171 Gene3D G3DSA:3.40.630.30 97 155 7.5E-15 T 28-03-2018 ALX04_RS14835 41762c52e3146d099a00581eb60e6902 325 Pfam PF01515 Phosphate acetyl/butaryl transferase 4 320 1.0E-119 T 28-03-2018 IPR002505 Phosphate acetyl/butaryl transferase GO:0008152|GO:0016746 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 ALX04_RS14835 41762c52e3146d099a00581eb60e6902 325 TIGRFAM TIGR00651 pta: phosphate acetyltransferase 18 320 3.2E-120 T 28-03-2018 IPR004614 Phosphate acetyltransferase GO:0016407 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 ALX04_RS14835 41762c52e3146d099a00581eb60e6902 325 Gene3D G3DSA:3.40.50.10750 143 296 1.4E-64 T 28-03-2018 ALX04_RS14835 41762c52e3146d099a00581eb60e6902 325 PIRSF PIRSF000428 1 325 2.7E-106 T 28-03-2018 IPR012147 Phosphate acetyl/butyryltransferase GO:0016746 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 ALX04_RS14835 41762c52e3146d099a00581eb60e6902 325 SUPERFAMILY SSF53659 3 322 7.81E-89 T 28-03-2018 ALX04_RS15245 9cd19f3eea726db7015032d894fdc05b 225 Gene3D G3DSA:3.40.50.1240 1 211 1.7E-42 T 28-03-2018 IPR029033 Histidine phosphatase superfamily ALX04_RS15245 9cd19f3eea726db7015032d894fdc05b 225 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 6 212 4.3E-36 T 28-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 ALX04_RS15245 9cd19f3eea726db7015032d894fdc05b 225 SMART SM00855 5 178 2.4E-22 T 28-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 ALX04_RS15245 9cd19f3eea726db7015032d894fdc05b 225 SUPERFAMILY SSF53254 6 210 3.27E-51 T 28-03-2018 IPR029033 Histidine phosphatase superfamily ALX04_RS15245 9cd19f3eea726db7015032d894fdc05b 225 PIRSF PIRSF000709 161 188 5.5 T 28-03-2018 ALX04_RS15245 9cd19f3eea726db7015032d894fdc05b 225 PIRSF PIRSF000709 1 95 2.8E-5 T 28-03-2018 ALX04_RS14905 5e8e14816e6b02d55b50d6c00fe74553 223 Gene3D G3DSA:3.20.20.450 5 223 1.4E-27 T 28-03-2018 IPR001633 EAL domain ALX04_RS14905 5e8e14816e6b02d55b50d6c00fe74553 223 Pfam PF00563 EAL domain 9 215 1.6E-20 T 28-03-2018 IPR001633 EAL domain ALX04_RS14905 5e8e14816e6b02d55b50d6c00fe74553 223 SMART SM00052 1 220 2.0E-6 T 28-03-2018 IPR001633 EAL domain ALX04_RS14905 5e8e14816e6b02d55b50d6c00fe74553 223 SUPERFAMILY SSF141868 8 221 9.42E-30 T 28-03-2018 IPR001633 EAL domain ALX04_RS05545 f3b60f66930a9f5f9511166807e7566d 131 TIGRFAM TIGR02209 ftsL_broad: cell division protein FtsL 48 131 1.8E-22 T 28-03-2018 IPR011922 Cell division protein FtsL GO:0007049|GO:0016021|GO:0051301 ALX04_RS05545 f3b60f66930a9f5f9511166807e7566d 131 Pfam PF04977 Septum formation initiator 58 123 5.7E-8 T 28-03-2018 IPR007060 Septum formation initiator FtsL/DivIC GO:0007049 ALX04_RS05545 f3b60f66930a9f5f9511166807e7566d 131 Hamap MF_00910 Cell division protein FtsL [ftsL]. 48 130 14.745 T 28-03-2018 IPR011922 Cell division protein FtsL GO:0007049|GO:0016021|GO:0051301 ALX04_RS09570 60085f7f41fceb83b40f5f1ae2f3eee6 620 Gene3D G3DSA:3.20.20.80 2 199 9.7E-33 T 28-03-2018 ALX04_RS09570 60085f7f41fceb83b40f5f1ae2f3eee6 620 SMART SM00287 559 618 8.1E-7 T 28-03-2018 IPR003646 SH3-like domain, bacterial-type ALX04_RS09570 60085f7f41fceb83b40f5f1ae2f3eee6 620 SMART SM00287 479 546 2.0 T 28-03-2018 IPR003646 SH3-like domain, bacterial-type ALX04_RS09570 60085f7f41fceb83b40f5f1ae2f3eee6 620 SMART SM00287 395 463 15.0 T 28-03-2018 IPR003646 SH3-like domain, bacterial-type ALX04_RS09570 60085f7f41fceb83b40f5f1ae2f3eee6 620 SMART SM00287 231 296 1.2 T 28-03-2018 IPR003646 SH3-like domain, bacterial-type ALX04_RS09570 60085f7f41fceb83b40f5f1ae2f3eee6 620 Pfam PF08460 Bacterial SH3 domain 557 616 6.1E-13 T 28-03-2018 IPR003646 SH3-like domain, bacterial-type ALX04_RS09570 60085f7f41fceb83b40f5f1ae2f3eee6 620 Pfam PF08460 Bacterial SH3 domain 478 540 1.5E-11 T 28-03-2018 IPR003646 SH3-like domain, bacterial-type ALX04_RS09570 60085f7f41fceb83b40f5f1ae2f3eee6 620 Pfam PF08460 Bacterial SH3 domain 394 456 4.5E-12 T 28-03-2018 IPR003646 SH3-like domain, bacterial-type ALX04_RS09570 60085f7f41fceb83b40f5f1ae2f3eee6 620 Pfam PF08460 Bacterial SH3 domain 310 372 9.2E-13 T 28-03-2018 IPR003646 SH3-like domain, bacterial-type ALX04_RS09570 60085f7f41fceb83b40f5f1ae2f3eee6 620 Pfam PF08460 Bacterial SH3 domain 228 290 1.4E-10 T 28-03-2018 IPR003646 SH3-like domain, bacterial-type ALX04_RS09570 60085f7f41fceb83b40f5f1ae2f3eee6 620 SUPERFAMILY SSF51445 4 189 9.48E-31 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily ALX04_RS09570 60085f7f41fceb83b40f5f1ae2f3eee6 620 Pfam PF01183 Glycosyl hydrolases family 25 4 167 9.2E-27 T 28-03-2018 IPR002053 Glycoside hydrolase, family 25 GO:0003796|GO:0009253|GO:0016998 ALX04_RS09570 60085f7f41fceb83b40f5f1ae2f3eee6 620 Gene3D G3DSA:2.30.30.410 377 463 4.0E-8 T 28-03-2018 ALX04_RS09570 60085f7f41fceb83b40f5f1ae2f3eee6 620 Gene3D G3DSA:2.30.30.410 296 376 5.9E-9 T 28-03-2018 ALX04_RS09570 60085f7f41fceb83b40f5f1ae2f3eee6 620 Gene3D G3DSA:2.30.30.410 203 295 3.6E-9 T 28-03-2018 ALX04_RS09570 60085f7f41fceb83b40f5f1ae2f3eee6 620 Gene3D G3DSA:2.30.30.410 464 540 3.4E-8 T 28-03-2018 ALX04_RS09570 60085f7f41fceb83b40f5f1ae2f3eee6 620 Gene3D G3DSA:2.30.30.410 541 618 1.6E-14 T 28-03-2018 ALX04_RS03780 774cc9877ee4e267b46e51f0d5cc9b9b 314 Pfam PF00589 Phage integrase family 113 286 4.3E-45 T 28-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 ALX04_RS03780 774cc9877ee4e267b46e51f0d5cc9b9b 314 Hamap MF_01808 Tyrosine recombinase XerC [xerC]. 4 300 51.12 T 28-03-2018 IPR023009 Tyrosine recombinase XerC/XerD ALX04_RS03780 774cc9877ee4e267b46e51f0d5cc9b9b 314 TIGRFAM TIGR02224 recomb_XerC: tyrosine recombinase XerC 9 301 1.4E-109 T 28-03-2018 IPR011931 Tyrosine recombinase XerC GO:0003677|GO:0006310|GO:0007049|GO:0007059|GO:0015074|GO:0051301 ALX04_RS03780 774cc9877ee4e267b46e51f0d5cc9b9b 314 SUPERFAMILY SSF56349 4 292 1.12E-56 T 28-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 ALX04_RS03780 774cc9877ee4e267b46e51f0d5cc9b9b 314 Pfam PF02899 Phage integrase, N-terminal SAM-like domain 7 88 3.8E-18 T 28-03-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 ALX04_RS03780 774cc9877ee4e267b46e51f0d5cc9b9b 314 Gene3D G3DSA:1.10.443.10 112 294 2.3E-44 T 28-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 ALX04_RS03780 774cc9877ee4e267b46e51f0d5cc9b9b 314 Gene3D G3DSA:1.10.150.130 2 111 1.0E-23 T 28-03-2018 IPR023109 Integrase/recombinase, N-terminal ALX04_RS14650 356ea111aec4695d516afe88550a555b 236 Gene3D G3DSA:3.20.20.450 5 223 1.6E-25 T 28-03-2018 IPR001633 EAL domain ALX04_RS14650 356ea111aec4695d516afe88550a555b 236 SUPERFAMILY SSF141868 6 220 9.02E-32 T 28-03-2018 IPR001633 EAL domain ALX04_RS14650 356ea111aec4695d516afe88550a555b 236 SMART SM00052 6 223 2.3E-6 T 28-03-2018 IPR001633 EAL domain ALX04_RS14650 356ea111aec4695d516afe88550a555b 236 Pfam PF00563 EAL domain 8 218 7.5E-22 T 28-03-2018 IPR001633 EAL domain ALX04_RS09815 badb6f3fa898a52abaf2c5bc8a4ee0b1 184 Pfam PF11611 Domain of unknown function (DUF4352) 61 177 1.9E-23 T 28-03-2018 IPR029051 Domain of unknown function DUF4352 ALX04_RS09815 badb6f3fa898a52abaf2c5bc8a4ee0b1 184 Gene3D G3DSA:2.60.40.1240 60 184 1.1E-23 T 28-03-2018 IPR029050 Immunoprotective extracellular, immunoglobulin-like domain ALX04_RS05360 a391aabc62df305007192f1d2cdbf832 72 ProDom PD055417 UPF0356 TRANSCRIPTIONAL REGULATOR SP0122 SH1862 BLI01669/BL01628 MW0973 LMOF2365_1049 BCE33L3734 SPYM3_1619/SPS0248 1 69 8.0E-34 T 28-03-2018 IPR009907 Protein of unknown function DUF1447 ALX04_RS05360 a391aabc62df305007192f1d2cdbf832 72 Hamap MF_01553 UPF0356 protein . 1 70 22.966 T 28-03-2018 IPR009907 Protein of unknown function DUF1447 ALX04_RS05360 a391aabc62df305007192f1d2cdbf832 72 Pfam PF07288 Protein of unknown function (DUF1447) 2 69 1.3E-31 T 28-03-2018 IPR009907 Protein of unknown function DUF1447 ALX04_RS11795 439a056f727fbbf2304173323c4f61b0 295 Gene3D G3DSA:1.10.10.10 1 87 7.0E-14 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS11795 439a056f727fbbf2304173323c4f61b0 295 SUPERFAMILY SSF53850 90 292 1.21E-21 T 28-03-2018 ALX04_RS11795 439a056f727fbbf2304173323c4f61b0 295 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 64 2.9E-14 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 ALX04_RS11795 439a056f727fbbf2304173323c4f61b0 295 Gene3D G3DSA:3.40.190.10 177 264 3.3E-11 T 28-03-2018 ALX04_RS11795 439a056f727fbbf2304173323c4f61b0 295 SUPERFAMILY SSF46785 2 88 6.32E-14 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS11795 439a056f727fbbf2304173323c4f61b0 295 Pfam PF03466 LysR substrate binding domain 88 290 8.8E-21 T 28-03-2018 IPR005119 LysR, substrate-binding ALX04_RS11795 439a056f727fbbf2304173323c4f61b0 295 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 3.1E-5 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 ALX04_RS11795 439a056f727fbbf2304173323c4f61b0 295 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 3.1E-5 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 ALX04_RS11795 439a056f727fbbf2304173323c4f61b0 295 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 3.1E-5 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 ALX04_RS11795 439a056f727fbbf2304173323c4f61b0 295 Gene3D G3DSA:3.40.190.10 88 176 2.1E-9 T 28-03-2018 ALX04_RS00665 0d3698a3c9cb168f1b09aa3e2217d1ad 309 Pfam PF02866 lactate/malate dehydrogenase, alpha/beta C-terminal domain 147 303 1.3E-31 T 28-03-2018 IPR022383 Lactate/malate dehydrogenase, C-terminal GO:0016616|GO:0055114 ALX04_RS00665 0d3698a3c9cb168f1b09aa3e2217d1ad 309 SUPERFAMILY SSF51735 3 146 1.0E-49 T 28-03-2018 IPR016040 NAD(P)-binding domain ALX04_RS00665 0d3698a3c9cb168f1b09aa3e2217d1ad 309 SUPERFAMILY SSF56327 145 306 7.21E-46 T 28-03-2018 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 ALX04_RS00665 0d3698a3c9cb168f1b09aa3e2217d1ad 309 PRINTS PR00086 L-lactate dehydrogenase signature 118 138 2.2E-35 T 28-03-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 ALX04_RS00665 0d3698a3c9cb168f1b09aa3e2217d1ad 309 PRINTS PR00086 L-lactate dehydrogenase signature 142 160 2.2E-35 T 28-03-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 ALX04_RS00665 0d3698a3c9cb168f1b09aa3e2217d1ad 309 PRINTS PR00086 L-lactate dehydrogenase signature 172 185 2.2E-35 T 28-03-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 ALX04_RS00665 0d3698a3c9cb168f1b09aa3e2217d1ad 309 PRINTS PR00086 L-lactate dehydrogenase signature 7 31 2.2E-35 T 28-03-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 ALX04_RS00665 0d3698a3c9cb168f1b09aa3e2217d1ad 309 PRINTS PR00086 L-lactate dehydrogenase signature 32 56 2.2E-35 T 28-03-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 ALX04_RS00665 0d3698a3c9cb168f1b09aa3e2217d1ad 309 TIGRFAM TIGR01771 L-LDH-NAD: L-lactate dehydrogenase 10 300 4.1E-106 T 28-03-2018 IPR011304 L-lactate dehydrogenase GO:0004459|GO:0005737|GO:0055114 KEGG: 00010+1.1.1.27|KEGG: 00270+1.1.1.27|KEGG: 00620+1.1.1.27|KEGG: 00640+1.1.1.27|MetaCyc: PWY-5481|MetaCyc: PWY-6901|Reactome: R-HSA-70268 ALX04_RS00665 0d3698a3c9cb168f1b09aa3e2217d1ad 309 Pfam PF00056 lactate/malate dehydrogenase, NAD binding domain 7 144 1.1E-41 T 28-03-2018 IPR001236 Lactate/malate dehydrogenase, N-terminal GO:0016491|GO:0055114 ALX04_RS00665 0d3698a3c9cb168f1b09aa3e2217d1ad 309 ProSitePatterns PS00064 L-lactate dehydrogenase active site. 174 180 - T 28-03-2018 IPR018177 L-lactate dehydrogenase, active site GO:0004459|GO:0055114 KEGG: 00010+1.1.1.27|KEGG: 00270+1.1.1.27|KEGG: 00620+1.1.1.27|KEGG: 00640+1.1.1.27|MetaCyc: PWY-5481|MetaCyc: PWY-6901|Reactome: R-HSA-70268 ALX04_RS00665 0d3698a3c9cb168f1b09aa3e2217d1ad 309 Gene3D G3DSA:3.40.50.720 6 144 1.8E-35 T 28-03-2018 ALX04_RS00665 0d3698a3c9cb168f1b09aa3e2217d1ad 309 PIRSF PIRSF000102 2 307 5.3E-92 T 28-03-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 ALX04_RS00665 0d3698a3c9cb168f1b09aa3e2217d1ad 309 Hamap MF_00488 L-lactate dehydrogenase [ldh]. 5 309 40.468 T 28-03-2018 IPR011304 L-lactate dehydrogenase GO:0004459|GO:0005737|GO:0055114 KEGG: 00010+1.1.1.27|KEGG: 00270+1.1.1.27|KEGG: 00620+1.1.1.27|KEGG: 00640+1.1.1.27|MetaCyc: PWY-5481|MetaCyc: PWY-6901|Reactome: R-HSA-70268 ALX04_RS00665 0d3698a3c9cb168f1b09aa3e2217d1ad 309 Gene3D G3DSA:3.90.110.10 145 308 1.2E-37 T 28-03-2018 ALX04_RS16050 1c507a0523cb3fd6b34915fb065b8f37 722 TIGRFAM TIGR02506 NrdE_NrdA: ribonucleoside-diphosphate reductase, alpha subunit 98 704 3.4E-147 T 28-03-2018 IPR013346 Ribonucleotide reductase, class I , alpha subunit GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 ALX04_RS16050 1c507a0523cb3fd6b34915fb065b8f37 722 ProSitePatterns PS00089 Ribonucleotide reductase large subunit signature. 559 581 - T 28-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 ALX04_RS16050 1c507a0523cb3fd6b34915fb065b8f37 722 TIGRFAM TIGR04170 RNR_1b_NrdE: ribonucleoside-diphosphate reductase, class 1b, alpha subunit 11 722 0.0 T 28-03-2018 IPR026459 Ribonucleotide reductase, class 1b, subunit NrdE KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227 ALX04_RS16050 1c507a0523cb3fd6b34915fb065b8f37 722 SUPERFAMILY SSF48168 22 169 3.27E-46 T 28-03-2018 IPR008926 Ribonucleotide reductase R1 subunit, N-terminal KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 ALX04_RS16050 1c507a0523cb3fd6b34915fb065b8f37 722 PRINTS PR01183 Ribonucleotide reductase large chain signature 377 388 1.5E-27 T 28-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 ALX04_RS16050 1c507a0523cb3fd6b34915fb065b8f37 722 PRINTS PR01183 Ribonucleotide reductase large chain signature 570 597 1.5E-27 T 28-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 ALX04_RS16050 1c507a0523cb3fd6b34915fb065b8f37 722 PRINTS PR01183 Ribonucleotide reductase large chain signature 421 444 1.5E-27 T 28-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 ALX04_RS16050 1c507a0523cb3fd6b34915fb065b8f37 722 PRINTS PR01183 Ribonucleotide reductase large chain signature 488 511 1.5E-27 T 28-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 ALX04_RS16050 1c507a0523cb3fd6b34915fb065b8f37 722 PRINTS PR01183 Ribonucleotide reductase large chain signature 460 482 1.5E-27 T 28-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 ALX04_RS16050 1c507a0523cb3fd6b34915fb065b8f37 722 PRINTS PR01183 Ribonucleotide reductase large chain signature 246 265 1.5E-27 T 28-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 ALX04_RS16050 1c507a0523cb3fd6b34915fb065b8f37 722 Pfam PF08343 Ribonucleotide reductase N-terminal 12 92 1.2E-25 T 28-03-2018 IPR013554 Ribonucleotide reductase N-terminal KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227 ALX04_RS16050 1c507a0523cb3fd6b34915fb065b8f37 722 Pfam PF02867 Ribonucleotide reductase, barrel domain 171 701 5.2E-135 T 28-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 ALX04_RS16050 1c507a0523cb3fd6b34915fb065b8f37 722 Pfam PF00317 Ribonucleotide reductase, all-alpha domain 94 166 3.8E-11 T 28-03-2018 IPR013509 Ribonucleotide reductase large subunit, N-terminal GO:0004748|GO:0005524|GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 ALX04_RS16050 1c507a0523cb3fd6b34915fb065b8f37 722 Gene3D G3DSA:3.20.70.20 73 709 8.5E-150 T 28-03-2018 ALX04_RS16050 1c507a0523cb3fd6b34915fb065b8f37 722 SUPERFAMILY SSF51998 170 704 1.25E-167 T 28-03-2018 ALX04_RS10800 576970f76a5f5933f76e70c47063ec46 192 Gene3D G3DSA:1.10.10.60 12 46 3.4E-5 T 28-03-2018 ALX04_RS10800 576970f76a5f5933f76e70c47063ec46 192 SUPERFAMILY SSF46689 17 79 2.1E-8 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 ALX04_RS10800 576970f76a5f5933f76e70c47063ec46 192 Gene3D G3DSA:1.10.357.10 47 177 1.4E-4 T 28-03-2018 ALX04_RS04350 7cb94705c57ba21f6d42fe215fea4ecd 258 Gene3D G3DSA:2.40.50.140 1 82 4.3E-17 T 28-03-2018 ALX04_RS04350 7cb94705c57ba21f6d42fe215fea4ecd 258 Pfam PF11967 Recombination protein O N terminal 1 77 3.7E-19 T 28-03-2018 IPR022572 DNA replication/recombination mediator RecO, N-terminal ALX04_RS04350 7cb94705c57ba21f6d42fe215fea4ecd 258 Hamap MF_00201 DNA repair protein RecO [recO]. 1 244 26.089 T 28-03-2018 IPR003717 Recombination protein O, RecO GO:0006281|GO:0006310 ALX04_RS04350 7cb94705c57ba21f6d42fe215fea4ecd 258 SUPERFAMILY SSF57863 81 233 2.51E-44 T 28-03-2018 ALX04_RS04350 7cb94705c57ba21f6d42fe215fea4ecd 258 TIGRFAM TIGR00613 reco: DNA repair protein RecO 4 244 1.3E-81 T 28-03-2018 IPR003717 Recombination protein O, RecO GO:0006281|GO:0006310 ALX04_RS04350 7cb94705c57ba21f6d42fe215fea4ecd 258 Pfam PF02565 Recombination protein O C terminal 84 239 2.2E-41 T 28-03-2018 IPR003717 Recombination protein O, RecO GO:0006281|GO:0006310 ALX04_RS04350 7cb94705c57ba21f6d42fe215fea4ecd 258 SUPERFAMILY SSF50249 2 77 2.4E-11 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold ALX04_RS01035 eef0a1330676bde15487d0e614bd14c5 390 Pfam PF04464 CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase 32 381 6.3E-45 T 28-03-2018 IPR007554 CDP-glycerol glycerophosphotransferase GO:0016020|GO:0047355 ALX04_RS01035 eef0a1330676bde15487d0e614bd14c5 390 SUPERFAMILY SSF53756 135 383 1.15E-10 T 28-03-2018 ALX04_RS09290 da5d5267b531416509324db184f2051f 506 Gene3D G3DSA:3.30.1490.100 305 444 7.3E-22 T 28-03-2018 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 ALX04_RS09290 da5d5267b531416509324db184f2051f 506 Gene3D G3DSA:1.10.150.20 224 296 2.7E-17 T 28-03-2018 ALX04_RS09290 da5d5267b531416509324db184f2051f 506 Pfam PF00817 impB/mucB/samB family 9 194 6.5E-25 T 28-03-2018 IPR001126 UmuC domain GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 ALX04_RS09290 da5d5267b531416509324db184f2051f 506 Gene3D G3DSA:3.30.70.270 158 223 6.6E-8 T 28-03-2018 ALX04_RS09290 da5d5267b531416509324db184f2051f 506 Gene3D G3DSA:3.30.70.270 45 157 3.3E-11 T 28-03-2018 ALX04_RS09290 da5d5267b531416509324db184f2051f 506 Pfam PF11799 impB/mucB/samB family C-terminal domain 303 429 3.9E-12 T 28-03-2018 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 ALX04_RS09290 da5d5267b531416509324db184f2051f 506 SUPERFAMILY SSF56672 113 289 1.6E-43 T 28-03-2018 ALX04_RS09290 da5d5267b531416509324db184f2051f 506 SUPERFAMILY SSF56672 4 78 1.6E-43 T 28-03-2018 ALX04_RS15055 1755a643c08b2e0169f3720d8f865546 813 SUPERFAMILY SSF53474 168 580 2.75E-97 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold ALX04_RS15055 1755a643c08b2e0169f3720d8f865546 813 SMART SM00940 1 157 3.4E-80 T 28-03-2018 IPR015251 X-Prolyl dipeptidyl aminopeptidase PepX, N-terminal domain GO:0006508|GO:0008239 ALX04_RS15055 1755a643c08b2e0169f3720d8f865546 813 Pfam PF02129 X-Pro dipeptidyl-peptidase (S15 family) 202 528 1.8E-81 T 28-03-2018 IPR000383 Xaa-Pro dipeptidyl-peptidase-like domain GO:0016787 ALX04_RS15055 1755a643c08b2e0169f3720d8f865546 813 PRINTS PR00923 Lactococcus X-Pro dipeptidyl-peptidase (S15) family signature 206 215 6.6E-41 T 28-03-2018 IPR008252 Peptidase S15, X-Pro dipeptidyl-peptidase GO:0004177|GO:0006508 ALX04_RS15055 1755a643c08b2e0169f3720d8f865546 813 PRINTS PR00923 Lactococcus X-Pro dipeptidyl-peptidase (S15) family signature 398 414 6.6E-41 T 28-03-2018 IPR008252 Peptidase S15, X-Pro dipeptidyl-peptidase GO:0004177|GO:0006508 ALX04_RS15055 1755a643c08b2e0169f3720d8f865546 813 PRINTS PR00923 Lactococcus X-Pro dipeptidyl-peptidase (S15) family signature 773 788 6.6E-41 T 28-03-2018 IPR008252 Peptidase S15, X-Pro dipeptidyl-peptidase GO:0004177|GO:0006508 ALX04_RS15055 1755a643c08b2e0169f3720d8f865546 813 PRINTS PR00923 Lactococcus X-Pro dipeptidyl-peptidase (S15) family signature 223 239 6.6E-41 T 28-03-2018 IPR008252 Peptidase S15, X-Pro dipeptidyl-peptidase GO:0004177|GO:0006508 ALX04_RS15055 1755a643c08b2e0169f3720d8f865546 813 PRINTS PR00923 Lactococcus X-Pro dipeptidyl-peptidase (S15) family signature 172 184 6.6E-41 T 28-03-2018 IPR008252 Peptidase S15, X-Pro dipeptidyl-peptidase GO:0004177|GO:0006508 ALX04_RS15055 1755a643c08b2e0169f3720d8f865546 813 PRINTS PR00923 Lactococcus X-Pro dipeptidyl-peptidase (S15) family signature 188 198 6.6E-41 T 28-03-2018 IPR008252 Peptidase S15, X-Pro dipeptidyl-peptidase GO:0004177|GO:0006508 ALX04_RS15055 1755a643c08b2e0169f3720d8f865546 813 PRINTS PR00923 Lactococcus X-Pro dipeptidyl-peptidase (S15) family signature 534 550 6.6E-41 T 28-03-2018 IPR008252 Peptidase S15, X-Pro dipeptidyl-peptidase GO:0004177|GO:0006508 ALX04_RS15055 1755a643c08b2e0169f3720d8f865546 813 Gene3D G3DSA:2.60.120.260 574 809 4.8E-27 T 28-03-2018 IPR008979 Galactose-binding domain-like ALX04_RS15055 1755a643c08b2e0169f3720d8f865546 813 SMART SM00939 542 805 5.7E-63 T 28-03-2018 IPR013736 Xaa-Pro dipeptidyl-peptidase, C-terminal GO:0008239 ALX04_RS15055 1755a643c08b2e0169f3720d8f865546 813 Gene3D G3DSA:3.40.50.1820 171 573 3.6E-31 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold ALX04_RS15055 1755a643c08b2e0169f3720d8f865546 813 Pfam PF09168 X-Prolyl dipeptidyl aminopeptidase PepX, N-terminal 1 157 8.9E-51 T 28-03-2018 IPR015251 X-Prolyl dipeptidyl aminopeptidase PepX, N-terminal domain GO:0006508|GO:0008239 ALX04_RS15055 1755a643c08b2e0169f3720d8f865546 813 SUPERFAMILY SSF81761 1 158 1.96E-42 T 28-03-2018 IPR015251 X-Prolyl dipeptidyl aminopeptidase PepX, N-terminal domain GO:0006508|GO:0008239 ALX04_RS15055 1755a643c08b2e0169f3720d8f865546 813 Hamap MF_00698 Xaa-Pro dipeptidyl-peptidase [pepX]. 1 808 33.894 T 28-03-2018 IPR008252 Peptidase S15, X-Pro dipeptidyl-peptidase GO:0004177|GO:0006508 ALX04_RS15055 1755a643c08b2e0169f3720d8f865546 813 Pfam PF08530 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain 554 802 1.1E-50 T 28-03-2018 IPR013736 Xaa-Pro dipeptidyl-peptidase, C-terminal GO:0008239 ALX04_RS15055 1755a643c08b2e0169f3720d8f865546 813 SUPERFAMILY SSF49785 603 812 1.34E-65 T 28-03-2018 IPR008979 Galactose-binding domain-like ALX04_RS15935 809ebd90408848f46404fd14fb4c9b32 278 Pfam PF00665 Integrase core domain 111 229 4.4E-22 T 28-03-2018 IPR001584 Integrase, catalytic core GO:0015074 ALX04_RS15935 809ebd90408848f46404fd14fb4c9b32 278 SUPERFAMILY SSF53098 107 270 1.05E-33 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 ALX04_RS15935 809ebd90408848f46404fd14fb4c9b32 278 Gene3D G3DSA:3.30.420.10 106 277 4.2E-34 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 ALX04_RS04160 57842ce8a5774f05d2ed36edb3452301 176 SUPERFAMILY SSF46689 138 166 2.87E-13 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 ALX04_RS04160 57842ce8a5774f05d2ed36edb3452301 176 SUPERFAMILY SSF46689 60 110 2.87E-13 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 ALX04_RS04160 57842ce8a5774f05d2ed36edb3452301 176 Gene3D G3DSA:1.10.10.60 62 165 1.8E-15 T 28-03-2018 ALX04_RS04160 57842ce8a5774f05d2ed36edb3452301 176 Gene3D G3DSA:1.10.10.10 2 59 5.8E-6 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS04160 57842ce8a5774f05d2ed36edb3452301 176 Pfam PF13518 Helix-turn-helix domain 65 118 3.1E-7 T 28-03-2018 ALX04_RS04160 57842ce8a5774f05d2ed36edb3452301 176 Pfam PF13518 Helix-turn-helix domain 9 56 1.0E-7 T 28-03-2018 ALX04_RS04160 57842ce8a5774f05d2ed36edb3452301 176 SUPERFAMILY SSF48295 3 57 1.73E-7 T 28-03-2018 IPR010921 Trp repressor/replication initiator GO:0043565 ALX04_RS14170 bc11bcff8b05254c8669408bd73762dd 267 Pfam PF01039 Carboxyl transferase domain 39 220 2.4E-17 T 28-03-2018 IPR034733 Acetyl-CoA carboxylase KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388|Reactome: R-HSA-196780 ALX04_RS14170 bc11bcff8b05254c8669408bd73762dd 267 SUPERFAMILY SSF52096 10 259 8.13E-65 T 28-03-2018 IPR029045 ClpP/crotonase-like domain ALX04_RS14170 bc11bcff8b05254c8669408bd73762dd 267 Hamap MF_01395 Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta, chloroplastic [accD]. 1 261 32.016 T 28-03-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 ALX04_RS14170 bc11bcff8b05254c8669408bd73762dd 267 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 143 161 1.0E-23 T 28-03-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 ALX04_RS14170 bc11bcff8b05254c8669408bd73762dd 267 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 209 220 1.0E-23 T 28-03-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 ALX04_RS14170 bc11bcff8b05254c8669408bd73762dd 267 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 109 123 1.0E-23 T 28-03-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 ALX04_RS14170 bc11bcff8b05254c8669408bd73762dd 267 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 180 197 1.0E-23 T 28-03-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 ALX04_RS14170 bc11bcff8b05254c8669408bd73762dd 267 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 231 240 1.0E-23 T 28-03-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 ALX04_RS14170 bc11bcff8b05254c8669408bd73762dd 267 Gene3D G3DSA:3.90.226.10 9 259 3.1E-60 T 28-03-2018 ALX04_RS07980 365ed7eab229ae077931268a8ed32317 593 Pfam PF02687 FtsX-like permease family 84 178 1.8E-7 T 28-03-2018 IPR003838 ABC transporter permease protein domain GO:0016020 ALX04_RS07980 365ed7eab229ae077931268a8ed32317 593 PIRSF PIRSF018968 1 405 5.1E-45 T 28-03-2018 IPR027022 ABC transporter permease protein, BceB-type GO:0006810 ALX04_RS07980 365ed7eab229ae077931268a8ed32317 593 PIRSF PIRSF018968 400 593 1.9E-28 T 28-03-2018 IPR027022 ABC transporter permease protein, BceB-type GO:0006810 ALX04_RS15920 70ba3781554a613fa1a7b6866dc4a0fc 93 TIGRFAM TIGR02384 RelB_DinJ: addiction module antitoxin, RelB/DinJ family 7 90 4.1E-18 T 28-03-2018 IPR007337 RelB antitoxin/Antitoxin DinJ ALX04_RS15920 70ba3781554a613fa1a7b6866dc4a0fc 93 Gene3D G3DSA:1.10.1220.10 6 46 0.012 T 28-03-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 ALX04_RS15920 70ba3781554a613fa1a7b6866dc4a0fc 93 Pfam PF04221 RelB antitoxin 8 83 1.2E-11 T 28-03-2018 IPR007337 RelB antitoxin/Antitoxin DinJ ALX04_RS02345 2fcb4e14e1d9ccb38791ceebb49a8db3 64 ProSitePatterns PS00936 Ribosomal protein L35 signature. 5 31 - T 28-03-2018 IPR018265 Ribosomal protein L35, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 ALX04_RS02345 2fcb4e14e1d9ccb38791ceebb49a8db3 64 PRINTS PR00064 Ribosomal protein L35 signature 21 35 6.3E-13 T 28-03-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 ALX04_RS02345 2fcb4e14e1d9ccb38791ceebb49a8db3 64 PRINTS PR00064 Ribosomal protein L35 signature 3 20 6.3E-13 T 28-03-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 ALX04_RS02345 2fcb4e14e1d9ccb38791ceebb49a8db3 64 PRINTS PR00064 Ribosomal protein L35 signature 36 54 6.3E-13 T 28-03-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 ALX04_RS02345 2fcb4e14e1d9ccb38791ceebb49a8db3 64 SUPERFAMILY SSF143034 2 62 1.44E-18 T 28-03-2018 ALX04_RS02345 2fcb4e14e1d9ccb38791ceebb49a8db3 64 Pfam PF01632 Ribosomal protein L35 2 62 3.4E-19 T 28-03-2018 IPR021137 Ribosomal protein L35 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 ALX04_RS02345 2fcb4e14e1d9ccb38791ceebb49a8db3 64 TIGRFAM TIGR00001 rpmI_bact: ribosomal protein bL35 2 63 2.3E-19 T 28-03-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 ALX04_RS02345 2fcb4e14e1d9ccb38791ceebb49a8db3 64 Hamap MF_00514 50S ribosomal protein L35 [rpmI]. 1 64 16.404 T 28-03-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 ALX04_RS02105 db621b7efdd06dd4eef6f4c502f726b4 200 Pfam PF00677 Lumazine binding domain 100 184 5.7E-22 T 28-03-2018 IPR026017 Lumazine-binding domain KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 ALX04_RS02105 db621b7efdd06dd4eef6f4c502f726b4 200 Pfam PF00677 Lumazine binding domain 3 87 1.3E-23 T 28-03-2018 IPR026017 Lumazine-binding domain KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 ALX04_RS02105 db621b7efdd06dd4eef6f4c502f726b4 200 SUPERFAMILY SSF63380 94 194 2.38E-28 T 28-03-2018 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 ALX04_RS02105 db621b7efdd06dd4eef6f4c502f726b4 200 SUPERFAMILY SSF63380 1 89 2.13E-25 T 28-03-2018 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 ALX04_RS02105 db621b7efdd06dd4eef6f4c502f726b4 200 TIGRFAM TIGR00187 ribE: riboflavin synthase, alpha subunit 1 195 1.2E-63 T 28-03-2018 IPR001783 Lumazine-binding protein KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 ALX04_RS02105 db621b7efdd06dd4eef6f4c502f726b4 200 PIRSF PIRSF000498 1 199 3.2E-67 T 28-03-2018 IPR001783 Lumazine-binding protein KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 ALX04_RS02105 db621b7efdd06dd4eef6f4c502f726b4 200 Gene3D G3DSA:2.40.30.20 94 191 2.0E-30 T 28-03-2018 IPR023366 ATP synthase subunit alpha-like domain KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 ALX04_RS02105 db621b7efdd06dd4eef6f4c502f726b4 200 Gene3D G3DSA:2.40.30.20 1 93 1.4E-28 T 28-03-2018 IPR023366 ATP synthase subunit alpha-like domain KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 ALX04_RS14270 58556924652ca4009d1289a13ded35e4 200 Gene3D G3DSA:1.10.1740.10 10 112 1.6E-18 T 28-03-2018 ALX04_RS14270 58556924652ca4009d1289a13ded35e4 200 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 31 127 5.8E-15 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 ALX04_RS14270 58556924652ca4009d1289a13ded35e4 200 SUPERFAMILY SSF88946 14 118 1.83E-19 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 ALX04_RS14270 58556924652ca4009d1289a13ded35e4 200 Pfam PF04542 Sigma-70 region 2 34 102 3.2E-10 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 ALX04_RS04635 1061e06d851dee50e5653dd86299e032 187 Gene3D G3DSA:1.10.132.20 76 186 7.4E-36 T 28-03-2018 ALX04_RS04635 1061e06d851dee50e5653dd86299e032 187 Gene3D G3DSA:1.10.132.20 5 75 3.3E-9 T 28-03-2018 ALX04_RS04635 1061e06d851dee50e5653dd86299e032 187 Pfam PF01765 Ribosome recycling factor 22 185 2.0E-61 T 28-03-2018 IPR023584 Ribosome recycling factor domain Reactome: R-HSA-5419276 ALX04_RS04635 1061e06d851dee50e5653dd86299e032 187 Hamap MF_00040 Ribosome-recycling factor [frr]. 5 187 26.114 T 28-03-2018 IPR002661 Ribosome recycling factor GO:0006412 Reactome: R-HSA-5419276 ALX04_RS04635 1061e06d851dee50e5653dd86299e032 187 TIGRFAM TIGR00496 frr: ribosome recycling factor 12 186 3.7E-67 T 28-03-2018 IPR002661 Ribosome recycling factor GO:0006412 Reactome: R-HSA-5419276 ALX04_RS04635 1061e06d851dee50e5653dd86299e032 187 SUPERFAMILY SSF55194 6 186 7.98E-67 T 28-03-2018 IPR023584 Ribosome recycling factor domain Reactome: R-HSA-5419276 ALX04_RS14730 94a2d710e67e37ba1be3f9f52a45682b 196 SUPERFAMILY SSF52096 11 194 5.64E-72 T 28-03-2018 IPR029045 ClpP/crotonase-like domain ALX04_RS14730 94a2d710e67e37ba1be3f9f52a45682b 196 ProSitePatterns PS00382 Endopeptidase Clp histidine active site. 112 125 - T 28-03-2018 IPR033135 ClpP, histidine active site ALX04_RS14730 94a2d710e67e37ba1be3f9f52a45682b 196 PRINTS PR00127 Clp protease catalytic subunit P signature 111 130 6.2E-49 T 28-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 ALX04_RS14730 94a2d710e67e37ba1be3f9f52a45682b 196 PRINTS PR00127 Clp protease catalytic subunit P signature 59 79 6.2E-49 T 28-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 ALX04_RS14730 94a2d710e67e37ba1be3f9f52a45682b 196 PRINTS PR00127 Clp protease catalytic subunit P signature 19 34 6.2E-49 T 28-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 ALX04_RS14730 94a2d710e67e37ba1be3f9f52a45682b 196 PRINTS PR00127 Clp protease catalytic subunit P signature 168 187 6.2E-49 T 28-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 ALX04_RS14730 94a2d710e67e37ba1be3f9f52a45682b 196 PRINTS PR00127 Clp protease catalytic subunit P signature 90 107 6.2E-49 T 28-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 ALX04_RS14730 94a2d710e67e37ba1be3f9f52a45682b 196 ProSitePatterns PS00381 Endopeptidase Clp serine active site. 90 101 - T 28-03-2018 IPR018215 ClpP, Ser active site ALX04_RS14730 94a2d710e67e37ba1be3f9f52a45682b 196 TIGRFAM TIGR00493 clpP: ATP-dependent Clp endopeptidase, proteolytic subunit ClpP 4 191 1.6E-94 T 28-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 ALX04_RS14730 94a2d710e67e37ba1be3f9f52a45682b 196 Pfam PF00574 Clp protease 12 192 1.5E-83 T 28-03-2018 IPR023562 Clp protease proteolytic subunit /Translocation-enhancing protein TepA ALX04_RS14730 94a2d710e67e37ba1be3f9f52a45682b 196 Gene3D G3DSA:3.90.226.10 2 194 1.4E-44 T 28-03-2018 ALX04_RS14730 94a2d710e67e37ba1be3f9f52a45682b 196 Hamap MF_00444 ATP-dependent Clp protease proteolytic subunit [clpP]. 3 193 41.831 T 28-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 ALX04_RS06125 748923c143d05e993a7fe82e72e80466 433 Pfam PF00675 Insulinase (Peptidase family M16) 50 151 2.6E-14 T 28-03-2018 IPR011765 Peptidase M16, N-terminal ALX04_RS06125 748923c143d05e993a7fe82e72e80466 433 Gene3D G3DSA:3.30.830.10 226 432 8.4E-12 T 28-03-2018 ALX04_RS06125 748923c143d05e993a7fe82e72e80466 433 Pfam PF05193 Peptidase M16 inactive domain 181 351 7.0E-16 T 28-03-2018 IPR007863 Peptidase M16, C-terminal ALX04_RS06125 748923c143d05e993a7fe82e72e80466 433 SUPERFAMILY SSF63411 14 219 2.02E-44 T 28-03-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 ALX04_RS06125 748923c143d05e993a7fe82e72e80466 433 SUPERFAMILY SSF63411 273 420 1.75E-13 T 28-03-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 ALX04_RS06125 748923c143d05e993a7fe82e72e80466 433 Gene3D G3DSA:3.30.830.10 1 225 1.1E-53 T 28-03-2018 ALX04_RS03425 b4e0337d2e70b9418744ba000931520d 454 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 15 416 8.6E-73 T 28-03-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 ALX04_RS03425 b4e0337d2e70b9418744ba000931520d 454 Pfam PF07690 Major Facilitator Superfamily 16 405 4.9E-52 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 ALX04_RS03425 b4e0337d2e70b9418744ba000931520d 454 Gene3D G3DSA:1.20.1250.20 247 453 4.7E-26 T 28-03-2018 ALX04_RS03425 b4e0337d2e70b9418744ba000931520d 454 PRINTS PR01036 Tetracycline resistance protein TetB signature 135 159 2.2E-7 T 28-03-2018 ALX04_RS03425 b4e0337d2e70b9418744ba000931520d 454 PRINTS PR01036 Tetracycline resistance protein TetB signature 297 321 2.2E-7 T 28-03-2018 ALX04_RS03425 b4e0337d2e70b9418744ba000931520d 454 PRINTS PR01036 Tetracycline resistance protein TetB signature 74 96 2.2E-7 T 28-03-2018 ALX04_RS03425 b4e0337d2e70b9418744ba000931520d 454 PRINTS PR01036 Tetracycline resistance protein TetB signature 262 287 2.2E-7 T 28-03-2018 ALX04_RS03425 b4e0337d2e70b9418744ba000931520d 454 Gene3D G3DSA:1.20.1250.20 1 196 2.0E-36 T 28-03-2018 ALX04_RS03425 b4e0337d2e70b9418744ba000931520d 454 SUPERFAMILY SSF103473 5 194 2.09E-68 T 28-03-2018 IPR020846 Major facilitator superfamily domain ALX04_RS03425 b4e0337d2e70b9418744ba000931520d 454 SUPERFAMILY SSF103473 243 449 2.09E-68 T 28-03-2018 IPR020846 Major facilitator superfamily domain ALX04_RS05295 0dcdca682ae70d21d1a60952c9e1d0bc 529 TIGRFAM TIGR03766 TIGR03766: conserved hypothetical integral membrane protein 14 507 7.2E-173 T 28-03-2018 IPR021200 Conserved hypothetical integral membrane protein ALX04_RS14880 ec017003146373a4ccf1055afa2378ed 221 Pfam PF07099 Protein of unknown function (DUF1361) 33 201 2.9E-38 T 28-03-2018 IPR009793 Protein of unknown function DUF1361 ALX04_RS11745 2760670fdf7b99cc843a1eab1f4a1aed 159 SUPERFAMILY SSF75217 1 157 2.03E-58 T 28-03-2018 IPR029028 Alpha/beta knot methyltransferases ALX04_RS11745 2760670fdf7b99cc843a1eab1f4a1aed 159 TIGRFAM TIGR00246 tRNA_RlmH_YbeA: rRNA large subunit m3Psi methyltransferase RlmH 2 159 2.3E-56 T 28-03-2018 IPR003742 RNA methyltransferase RlmH GO:0005737|GO:0006364|GO:0008168 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 ALX04_RS11745 2760670fdf7b99cc843a1eab1f4a1aed 159 Pfam PF02590 Predicted SPOUT methyltransferase 1 158 4.9E-57 T 28-03-2018 IPR003742 RNA methyltransferase RlmH GO:0005737|GO:0006364|GO:0008168 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 ALX04_RS11745 2760670fdf7b99cc843a1eab1f4a1aed 159 PIRSF PIRSF004505 1 159 1.2E-50 T 28-03-2018 IPR003742 RNA methyltransferase RlmH GO:0005737|GO:0006364|GO:0008168 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 ALX04_RS11745 2760670fdf7b99cc843a1eab1f4a1aed 159 Hamap MF_00658 Ribosomal RNA large subunit methyltransferase H [rlmH]. 1 159 29.449 T 28-03-2018 IPR003742 RNA methyltransferase RlmH GO:0005737|GO:0006364|GO:0008168 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 ALX04_RS11745 2760670fdf7b99cc843a1eab1f4a1aed 159 Gene3D G3DSA:3.40.1280.10 1 159 9.5E-60 T 28-03-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal ALX04_RS15440 4b8703b01aa3b37c527f0de242108bfd 144 Pfam PF03610 PTS system fructose IIA component 4 116 6.9E-20 T 28-03-2018 IPR004701 Phosphotransferase system, mannose-type IIA component GO:0009401|GO:0016021 ALX04_RS15440 4b8703b01aa3b37c527f0de242108bfd 144 Gene3D G3DSA:3.40.50.510 3 131 1.7E-22 T 28-03-2018 IPR004701 Phosphotransferase system, mannose-type IIA component GO:0009401|GO:0016021 ALX04_RS15440 4b8703b01aa3b37c527f0de242108bfd 144 SUPERFAMILY SSF53062 3 131 3.14E-25 T 28-03-2018 IPR004701 Phosphotransferase system, mannose-type IIA component GO:0009401|GO:0016021 ALX04_RS11425 f10c0caa378ee36298bec4d377a44358 339 TIGRFAM TIGR00825 EIIBC-GUT: PTS system, glucitol/sorbitol-specific, IIBC component 7 337 2.0E-140 T 28-03-2018 IPR004702 Phosphotransferease, sorbitol phosphotransferase enzyme II GO:0008982|GO:0009401|GO:0016021 KEGG: 00051+2.7.1.198|KEGG: 00710+2.7.1.19|MetaCyc: PWY-5723 ALX04_RS11425 f10c0caa378ee36298bec4d377a44358 339 Pfam PF07663 Sorbitol phosphotransferase enzyme II C-terminus 245 337 4.5E-45 T 28-03-2018 IPR011638 Sorbitol phosphotransferase enzyme II, C-terminal GO:0008982|GO:0009401|GO:0016021 KEGG: 00051+2.7.1.198|KEGG: 00710+2.7.1.19|MetaCyc: PWY-5723 ALX04_RS11425 f10c0caa378ee36298bec4d377a44358 339 Pfam PF03612 Sorbitol phosphotransferase enzyme II N-terminus 7 190 5.2E-75 T 28-03-2018 IPR011618 Sorbitol phosphotransferase enzyme II, N-terminal GO:0008982|GO:0009401|GO:0016021 KEGG: 00051+2.7.1.198|KEGG: 00710+2.7.1.19|MetaCyc: PWY-5723 ALX04_RS03035 ba1abf36f7b0395921681f90c3b2c32f 310 SUPERFAMILY SSF55048 123 190 4.19E-12 T 28-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 ALX04_RS03035 ba1abf36f7b0395921681f90c3b2c32f 310 SUPERFAMILY SSF52151 192 293 7.32E-55 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 ALX04_RS03035 ba1abf36f7b0395921681f90c3b2c32f 310 SUPERFAMILY SSF52151 2 122 7.32E-55 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 ALX04_RS03035 ba1abf36f7b0395921681f90c3b2c32f 310 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 6 290 5.0E-25 T 28-03-2018 IPR020801 Polyketide synthase, acyl transferase domain ALX04_RS03035 ba1abf36f7b0395921681f90c3b2c32f 310 Gene3D G3DSA:3.40.366.10 1 176 5.3E-34 T 28-03-2018 ALX04_RS03035 ba1abf36f7b0395921681f90c3b2c32f 310 PIRSF PIRSF000446 1 302 1.3E-63 T 28-03-2018 IPR024925 Malonyl CoA-acyl carrier protein transacylase KEGG: 00061+2.3.1.39|MetaCyc: PWY-4381|MetaCyc: PWY-6799|MetaCyc: PWY-7388 ALX04_RS03035 ba1abf36f7b0395921681f90c3b2c32f 310 Pfam PF00698 Acyl transferase domain 6 280 1.2E-28 T 28-03-2018 IPR014043 Acyl transferase ALX04_RS03035 ba1abf36f7b0395921681f90c3b2c32f 310 Gene3D G3DSA:3.40.366.10 177 304 1.9E-24 T 28-03-2018 ALX04_RS07205 39eb77f95c948d3a03f728402235eca7 324 Gene3D G3DSA:3.40.50.720 1 178 4.8E-15 T 28-03-2018 ALX04_RS07205 39eb77f95c948d3a03f728402235eca7 324 TIGRFAM TIGR00745 apbA_panE: 2-dehydropantoate 2-reductase 2 309 9.9E-57 T 28-03-2018 IPR003710 Ketopantoate reductase ApbA/PanE GO:0005737|GO:0015940|GO:0016491|GO:0055114 KEGG: 00052+1.1.1.16|KEGG: 00770+1.1.1.169|MetaCyc: PWY-6654|MetaCyc: PWY-7862 ALX04_RS07205 39eb77f95c948d3a03f728402235eca7 324 SUPERFAMILY SSF48179 183 310 1.19E-27 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 ALX04_RS07205 39eb77f95c948d3a03f728402235eca7 324 SUPERFAMILY SSF51735 1 126 1.79E-8 T 28-03-2018 IPR016040 NAD(P)-binding domain ALX04_RS07205 39eb77f95c948d3a03f728402235eca7 324 Pfam PF02558 Ketopantoate reductase PanE/ApbA 4 146 2.4E-25 T 28-03-2018 IPR013332 Ketopantoate reductase, N-terminal domain GO:0008677|GO:0055114 KEGG: 00052+1.1.1.16|KEGG: 00770+1.1.1.169|MetaCyc: PWY-6654|MetaCyc: PWY-7862 ALX04_RS07205 39eb77f95c948d3a03f728402235eca7 324 Pfam PF08546 Ketopantoate reductase PanE/ApbA C terminal 183 308 1.6E-26 T 28-03-2018 IPR013752 Ketopantoate reductase, C-terminal domain GO:0016491|GO:0050661|GO:0055114 KEGG: 00052+1.1.1.16|KEGG: 00770+1.1.1.169|MetaCyc: PWY-6654|MetaCyc: PWY-7862 ALX04_RS07205 39eb77f95c948d3a03f728402235eca7 324 Gene3D G3DSA:1.10.1040.10 183 319 8.0E-30 T 28-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 ALX04_RS03915 e86148b8b570caae926e9a0e9a3f91cf 436 TIGRFAM TIGR03594 GTPase_EngA: ribosome-associated GTPase EngA 4 431 5.9E-173 T 28-03-2018 IPR016484 GTP-binding protein EngA GO:0005525 ALX04_RS03915 e86148b8b570caae926e9a0e9a3f91cf 436 Hamap MF_00195 GTPase Der [der]. 3 436 40.401 T 28-03-2018 IPR016484 GTP-binding protein EngA GO:0005525 ALX04_RS03915 e86148b8b570caae926e9a0e9a3f91cf 436 Gene3D G3DSA:1.20.120.430 71 241 3.2E-42 T 28-03-2018 ALX04_RS03915 e86148b8b570caae926e9a0e9a3f91cf 436 Gene3D G3DSA:1.20.120.430 242 355 1.8E-16 T 28-03-2018 ALX04_RS03915 e86148b8b570caae926e9a0e9a3f91cf 436 Gene3D G3DSA:1.20.120.430 1 70 1.4E-18 T 28-03-2018 ALX04_RS03915 e86148b8b570caae926e9a0e9a3f91cf 436 SUPERFAMILY SSF52540 5 171 5.07E-45 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase ALX04_RS03915 e86148b8b570caae926e9a0e9a3f91cf 436 Pfam PF14714 KH-domain-like of EngA bacterial GTPase enzymes, C-terminal 353 431 2.4E-33 T 28-03-2018 IPR032859 GTPase Der, C-terminal KH-domain-like ALX04_RS03915 e86148b8b570caae926e9a0e9a3f91cf 436 Gene3D G3DSA:3.30.300.20 356 434 3.7E-35 T 28-03-2018 IPR015946 K homology domain-like, alpha/beta ALX04_RS03915 e86148b8b570caae926e9a0e9a3f91cf 436 Pfam PF01926 50S ribosome-binding GTPase 6 120 8.9E-26 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 ALX04_RS03915 e86148b8b570caae926e9a0e9a3f91cf 436 Pfam PF01926 50S ribosome-binding GTPase 177 295 1.9E-25 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 ALX04_RS03915 e86148b8b570caae926e9a0e9a3f91cf 436 SUPERFAMILY SSF52540 138 433 4.39E-69 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase ALX04_RS03915 e86148b8b570caae926e9a0e9a3f91cf 436 PIRSF PIRSF006485 2 436 2.9E-170 T 28-03-2018 IPR016484 GTP-binding protein EngA GO:0005525 ALX04_RS03915 e86148b8b570caae926e9a0e9a3f91cf 436 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 2 151 4.5E-27 T 28-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 ALX04_RS03915 e86148b8b570caae926e9a0e9a3f91cf 436 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 175 341 4.0E-26 T 28-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 ALX04_RS09040 11e53f8984b1ea1b06ff6ee8f922aa33 178 ProSitePatterns PS01117 MarR-type HTH domain signature. 72 106 - T 28-03-2018 IPR023187 Transcriptional regulator MarR-type, conserved site ALX04_RS09040 11e53f8984b1ea1b06ff6ee8f922aa33 178 SMART SM00347 29 133 9.3E-19 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 ALX04_RS09040 11e53f8984b1ea1b06ff6ee8f922aa33 178 Gene3D G3DSA:1.10.10.10 17 150 1.8E-28 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS09040 11e53f8984b1ea1b06ff6ee8f922aa33 178 SUPERFAMILY SSF46785 38 148 1.53E-29 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS09040 11e53f8984b1ea1b06ff6ee8f922aa33 178 PRINTS PR00598 Bacterial regulatory protein MarR family signature 123 143 5.8E-14 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 ALX04_RS09040 11e53f8984b1ea1b06ff6ee8f922aa33 178 PRINTS PR00598 Bacterial regulatory protein MarR family signature 93 109 5.8E-14 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 ALX04_RS09040 11e53f8984b1ea1b06ff6ee8f922aa33 178 PRINTS PR00598 Bacterial regulatory protein MarR family signature 57 73 5.8E-14 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 ALX04_RS09040 11e53f8984b1ea1b06ff6ee8f922aa33 178 PRINTS PR00598 Bacterial regulatory protein MarR family signature 74 89 5.8E-14 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 ALX04_RS09040 11e53f8984b1ea1b06ff6ee8f922aa33 178 SMART SM00529 58 146 0.0087 T 28-03-2018 IPR022689 Iron dependent repressor GO:0003700|GO:0006355|GO:0046914 ALX04_RS09040 11e53f8984b1ea1b06ff6ee8f922aa33 178 Pfam PF12802 MarR family 43 96 5.1E-13 T 28-03-2018 ALX04_RS00345 21419edbea88982ebbd4590bf70267ae 1201 Pfam PF10385 RNA polymerase beta subunit external 1 domain 552 619 1.3E-25 T 28-03-2018 IPR019462 DNA-directed RNA polymerase, beta subunit, external 1 domain GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 ALX04_RS00345 21419edbea88982ebbd4590bf70267ae 1201 Pfam PF04565 RNA polymerase Rpb2, domain 3 474 542 1.3E-29 T 28-03-2018 IPR007645 RNA polymerase Rpb2, domain 3 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 ALX04_RS00345 21419edbea88982ebbd4590bf70267ae 1201 Gene3D G3DSA:3.90.1100.10 20 213 6.9E-58 T 28-03-2018 ALX04_RS00345 21419edbea88982ebbd4590bf70267ae 1201 Gene3D G3DSA:3.90.1100.10 608 676 5.5E-12 T 28-03-2018 ALX04_RS00345 21419edbea88982ebbd4590bf70267ae 1201 Gene3D G3DSA:3.90.1100.10 298 607 6.7E-81 T 28-03-2018 ALX04_RS00345 21419edbea88982ebbd4590bf70267ae 1201 Pfam PF04560 RNA polymerase Rpb2, domain 7 1068 1142 4.2E-26 T 28-03-2018 IPR007641 RNA polymerase Rpb2, domain 7 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 ALX04_RS00345 21419edbea88982ebbd4590bf70267ae 1201 Pfam PF04561 RNA polymerase Rpb2, domain 2 140 288 1.8E-21 T 28-03-2018 IPR007642 RNA polymerase Rpb2, domain 2 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 ALX04_RS00345 21419edbea88982ebbd4590bf70267ae 1201 Pfam PF04561 RNA polymerase Rpb2, domain 2 381 415 1.7E-6 T 28-03-2018 IPR007642 RNA polymerase Rpb2, domain 2 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 ALX04_RS00345 21419edbea88982ebbd4590bf70267ae 1201 Gene3D G3DSA:2.40.270.10 844 1052 9.0E-76 T 28-03-2018 IPR007120 DNA-directed RNA polymerase, subunit 2, domain 6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 ALX04_RS00345 21419edbea88982ebbd4590bf70267ae 1201 Gene3D G3DSA:3.90.1800.10 1069 1114 1.2E-11 T 28-03-2018 ALX04_RS00345 21419edbea88982ebbd4590bf70267ae 1201 SUPERFAMILY SSF64484 372 1155 0.0 T 28-03-2018 ALX04_RS00345 21419edbea88982ebbd4590bf70267ae 1201 SUPERFAMILY SSF64484 13 293 0.0 T 28-03-2018 ALX04_RS00345 21419edbea88982ebbd4590bf70267ae 1201 TIGRFAM TIGR02013 rpoB: DNA-directed RNA polymerase, beta subunit 212 893 4.9E-299 T 28-03-2018 IPR010243 DNA-directed RNA polymerase beta subunit, bacterial-type GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 ALX04_RS00345 21419edbea88982ebbd4590bf70267ae 1201 Pfam PF04563 RNA polymerase beta subunit 28 459 3.1E-27 T 28-03-2018 IPR007644 RNA polymerase, beta subunit, protrusion GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 ALX04_RS00345 21419edbea88982ebbd4590bf70267ae 1201 ProSitePatterns PS01166 RNA polymerases beta chain signature. 919 931 - T 28-03-2018 IPR007121 RNA polymerase, beta subunit, conserved site GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 ALX04_RS00345 21419edbea88982ebbd4590bf70267ae 1201 Hamap MF_01321 DNA-directed RNA polymerase subunit beta [rpoB]. 15 1144 12.411 T 28-03-2018 IPR010243 DNA-directed RNA polymerase beta subunit, bacterial-type GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 ALX04_RS00345 21419edbea88982ebbd4590bf70267ae 1201 Gene3D G3DSA:2.40.50.100 677 748 1.0E-23 T 28-03-2018 ALX04_RS00345 21419edbea88982ebbd4590bf70267ae 1201 Gene3D G3DSA:2.40.270.10 749 843 8.5E-12 T 28-03-2018 IPR007120 DNA-directed RNA polymerase, subunit 2, domain 6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 ALX04_RS00345 21419edbea88982ebbd4590bf70267ae 1201 Pfam PF00562 RNA polymerase Rpb2, domain 6 681 1066 2.8E-163 T 28-03-2018 IPR007120 DNA-directed RNA polymerase, subunit 2, domain 6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 ALX04_RS00530 2222e7f0f236a483974ca59dc7f31600 163 Pfam PF07009 NusG domain II 25 149 1.3E-30 T 28-03-2018 IPR024045 NusG, domain 2 ALX04_RS00530 2222e7f0f236a483974ca59dc7f31600 163 Gene3D G3DSA:2.60.320.10 49 157 1.9E-29 T 28-03-2018 ALX04_RS11540 2209ead5df6ec277aff85c6c7461e5e2 636 Hamap MF_00129 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG [mnmG]. 10 632 41.791 T 28-03-2018 IPR004416 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG GO:0002098 Reactome: R-HSA-6787450 ALX04_RS11540 2209ead5df6ec277aff85c6c7461e5e2 636 Gene3D G3DSA:3.50.50.60 10 272 3.6E-70 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ALX04_RS11540 2209ead5df6ec277aff85c6c7461e5e2 636 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 153 171 2.8E-6 T 28-03-2018 ALX04_RS11540 2209ead5df6ec277aff85c6c7461e5e2 636 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 14 33 2.8E-6 T 28-03-2018 ALX04_RS11540 2209ead5df6ec277aff85c6c7461e5e2 636 Pfam PF13932 GidA associated domain 409 623 3.7E-79 T 28-03-2018 IPR026904 GidA associated domain 3 Reactome: R-HSA-6787450 ALX04_RS11540 2209ead5df6ec277aff85c6c7461e5e2 636 SMART SM01228 554 625 9.2E-39 T 28-03-2018 ALX04_RS11540 2209ead5df6ec277aff85c6c7461e5e2 636 TIGRFAM TIGR00136 gidA: tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA 12 629 4.5E-280 T 28-03-2018 IPR004416 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG GO:0002098 Reactome: R-HSA-6787450 ALX04_RS11540 2209ead5df6ec277aff85c6c7461e5e2 636 ProSitePatterns PS01281 Glucose inhibited division protein A family signature 2. 376 399 - T 28-03-2018 IPR020595 MnmG-related, conserved site Reactome: R-HSA-6787450 ALX04_RS11540 2209ead5df6ec277aff85c6c7461e5e2 636 SUPERFAMILY SSF51905 11 71 1.84E-47 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ALX04_RS11540 2209ead5df6ec277aff85c6c7461e5e2 636 SUPERFAMILY SSF51905 102 269 1.84E-47 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ALX04_RS11540 2209ead5df6ec277aff85c6c7461e5e2 636 ProSitePatterns PS01280 Glucose inhibited division protein A family signature 1. 281 295 - T 28-03-2018 IPR020595 MnmG-related, conserved site Reactome: R-HSA-6787450 ALX04_RS11540 2209ead5df6ec277aff85c6c7461e5e2 636 Pfam PF01134 Glucose inhibited division protein A 13 405 5.1E-166 T 28-03-2018 IPR002218 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG-related GO:0008033|GO:0050660 Reactome: R-HSA-6787450 ALX04_RS11540 2209ead5df6ec277aff85c6c7461e5e2 636 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 13 35 2.5E-6 T 28-03-2018 ALX04_RS11540 2209ead5df6ec277aff85c6c7461e5e2 636 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 156 165 2.5E-6 T 28-03-2018 ALX04_RS01285 5461b02aa09b6929c5031306e1056ffd 81 SUPERFAMILY SSF143120 18 72 6.93E-5 T 28-03-2018 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM ALX04_RS01285 5461b02aa09b6929c5031306e1056ffd 81 Gene3D G3DSA:3.40.1620.10 18 57 9.3E-4 T 28-03-2018 ALX04_RS14630 9bcd0340950ccd623d2436e8a44b55cb 312 Gene3D G3DSA:3.50.50.60 238 310 3.0E-9 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ALX04_RS14630 9bcd0340950ccd623d2436e8a44b55cb 312 SUPERFAMILY SSF51905 1 299 9.72E-60 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ALX04_RS14630 9bcd0340950ccd623d2436e8a44b55cb 312 Gene3D G3DSA:3.50.50.60 124 237 2.4E-26 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ALX04_RS14630 9bcd0340950ccd623d2436e8a44b55cb 312 Gene3D G3DSA:3.50.50.60 1 123 1.8E-24 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ALX04_RS14630 9bcd0340950ccd623d2436e8a44b55cb 312 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 266 284 1.2E-69 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 ALX04_RS14630 9bcd0340950ccd623d2436e8a44b55cb 312 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 193 209 1.2E-69 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 ALX04_RS14630 9bcd0340950ccd623d2436e8a44b55cb 312 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 59 69 1.2E-69 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 ALX04_RS14630 9bcd0340950ccd623d2436e8a44b55cb 312 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 6 28 1.2E-69 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 ALX04_RS14630 9bcd0340950ccd623d2436e8a44b55cb 312 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 39 54 1.2E-69 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 ALX04_RS14630 9bcd0340950ccd623d2436e8a44b55cb 312 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 104 112 1.2E-69 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 ALX04_RS14630 9bcd0340950ccd623d2436e8a44b55cb 312 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 126 138 1.2E-69 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 ALX04_RS14630 9bcd0340950ccd623d2436e8a44b55cb 312 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 232 253 1.2E-69 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 ALX04_RS14630 9bcd0340950ccd623d2436e8a44b55cb 312 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 141 165 1.2E-69 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 ALX04_RS14630 9bcd0340950ccd623d2436e8a44b55cb 312 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 5 292 2.2E-52 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ALX04_RS14630 9bcd0340950ccd623d2436e8a44b55cb 312 TIGRFAM TIGR01292 TRX_reduct: thioredoxin-disulfide reductase 5 303 1.7E-116 T 28-03-2018 IPR005982 Thioredoxin reductase GO:0004791|GO:0005737|GO:0019430|GO:0055114 KEGG: 00450+1.8.1.9 ALX04_RS14630 9bcd0340950ccd623d2436e8a44b55cb 312 ProSitePatterns PS00573 Pyridine nucleotide-disulphide oxidoreductases class-II active site. 133 153 - T 28-03-2018 IPR008255 Pyridine nucleotide-disulphide oxidoreductase, class-II, active site GO:0016491|GO:0055114 ALX04_RS14630 9bcd0340950ccd623d2436e8a44b55cb 312 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 230 246 5.5E-38 T 28-03-2018 ALX04_RS14630 9bcd0340950ccd623d2436e8a44b55cb 312 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 103 121 5.5E-38 T 28-03-2018 ALX04_RS14630 9bcd0340950ccd623d2436e8a44b55cb 312 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 256 278 5.5E-38 T 28-03-2018 ALX04_RS14630 9bcd0340950ccd623d2436e8a44b55cb 312 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 7 26 5.5E-38 T 28-03-2018 ALX04_RS14630 9bcd0340950ccd623d2436e8a44b55cb 312 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 145 163 5.5E-38 T 28-03-2018 ALX04_RS09870 241d4038351cb3e67cdcd8ccd0a6d934 309 Gene3D G3DSA:1.10.4030.10 22 124 3.8E-5 T 28-03-2018 ALX04_RS09870 241d4038351cb3e67cdcd8ccd0a6d934 309 SUPERFAMILY SSF109998 36 166 1.41E-10 T 28-03-2018 IPR027304 Trigger factor/SurA domain ALX04_RS09870 241d4038351cb3e67cdcd8ccd0a6d934 309 Hamap MF_01145 Foldase protein PrsA [prsA]. 3 304 16.946 T 28-03-2018 IPR023059 Foldase protein PrsA GO:0003755 ALX04_RS09870 241d4038351cb3e67cdcd8ccd0a6d934 309 SUPERFAMILY SSF54534 141 219 4.22E-7 T 28-03-2018 ALX04_RS09870 241d4038351cb3e67cdcd8ccd0a6d934 309 Gene3D G3DSA:3.10.50.40 134 241 4.8E-11 T 28-03-2018 ALX04_RS10960 1133761aa2fb1ec72124abf454162448 336 SMART SM00354 1 72 1.3E-6 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 ALX04_RS10960 1133761aa2fb1ec72124abf454162448 336 Gene3D G3DSA:3.40.50.2300 166 307 1.6E-23 T 28-03-2018 ALX04_RS10960 1133761aa2fb1ec72124abf454162448 336 SUPERFAMILY SSF47413 2 57 1.69E-10 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 ALX04_RS10960 1133761aa2fb1ec72124abf454162448 336 Pfam PF13377 Periplasmic binding protein-like domain 160 328 1.2E-30 T 28-03-2018 ALX04_RS10960 1133761aa2fb1ec72124abf454162448 336 Gene3D G3DSA:3.40.50.2300 52 165 4.4E-8 T 28-03-2018 ALX04_RS10960 1133761aa2fb1ec72124abf454162448 336 Pfam PF00356 Bacterial regulatory proteins, lacI family 3 48 9.9E-11 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 ALX04_RS10960 1133761aa2fb1ec72124abf454162448 336 SUPERFAMILY SSF53822 71 328 3.21E-34 T 28-03-2018 IPR028082 Periplasmic binding protein-like I ALX04_RS10960 1133761aa2fb1ec72124abf454162448 336 Gene3D G3DSA:1.10.260.40 1 51 9.7E-13 T 28-03-2018 ALX04_RS00090 5caca32a141da23add43ea258893d745 108 SUPERFAMILY SSF46785 11 85 1.33E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS00090 5caca32a141da23add43ea258893d745 108 Pfam PF01022 Bacterial regulatory protein, arsR family 25 69 6.6E-11 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 ALX04_RS00090 5caca32a141da23add43ea258893d745 108 Gene3D G3DSA:1.10.10.10 1 97 1.0E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS00090 5caca32a141da23add43ea258893d745 108 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 67 82 6.7E-9 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 ALX04_RS00090 5caca32a141da23add43ea258893d745 108 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 18 33 6.7E-9 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 ALX04_RS00090 5caca32a141da23add43ea258893d745 108 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 52 67 6.7E-9 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 ALX04_RS00090 5caca32a141da23add43ea258893d745 108 SMART SM00418 16 93 1.1E-11 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 ALX04_RS04720 1094300f745b00c93c632a80beb13511 130 SUPERFAMILY SSF51261 3 75 3.66E-5 T 28-03-2018 IPR011055 Duplicated hybrid motif ALX04_RS04720 1094300f745b00c93c632a80beb13511 130 Gene3D G3DSA:2.70.70.10 4 102 0.0028 T 28-03-2018 ALX04_RS14370 6a2907b3719600d391652788b4ed8bce 102 SUPERFAMILY SSF82607 8 100 8.37E-31 T 28-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family ALX04_RS14370 6a2907b3719600d391652788b4ed8bce 102 Hamap MF_00274 Nucleoid-associated protein YbaB [ybaB]. 6 100 21.862 T 28-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family ALX04_RS14370 6a2907b3719600d391652788b4ed8bce 102 PIRSF PIRSF004555 4 102 9.2E-33 T 28-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family ALX04_RS14370 6a2907b3719600d391652788b4ed8bce 102 Pfam PF02575 YbaB/EbfC DNA-binding family 12 101 2.9E-32 T 28-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family ALX04_RS14370 6a2907b3719600d391652788b4ed8bce 102 TIGRFAM TIGR00103 DNA_YbaB_EbfC: DNA-binding protein, YbaB/EbfC family 1 101 3.6E-26 T 28-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family ALX04_RS14370 6a2907b3719600d391652788b4ed8bce 102 Gene3D G3DSA:3.30.1310.10 1 102 1.6E-33 T 28-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family ALX04_RS13435 d07e61d38bacc42e0bf400877e3a011b 258 Gene3D G3DSA:3.60.110.10 1 258 1.4E-82 T 28-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 ALX04_RS13435 d07e61d38bacc42e0bf400877e3a011b 258 SUPERFAMILY SSF56317 1 258 2.49E-79 T 28-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 ALX04_RS13435 d07e61d38bacc42e0bf400877e3a011b 258 Pfam PF00795 Carbon-nitrogen hydrolase 2 244 2.7E-51 T 28-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 ALX04_RS15750 490e80c8a6f383f0a7d01e5502ea94f3 777 Pfam PF08924 Domain of unknown function (DUF1906) 310 437 1.1E-37 T 28-03-2018 IPR015020 Protein of unknown function DUF1906 ALX04_RS15750 490e80c8a6f383f0a7d01e5502ea94f3 777 Gene3D G3DSA:1.10.101.10 157 218 1.7E-4 T 28-03-2018 IPR002477 Peptidoglycan binding-like ALX04_RS15750 490e80c8a6f383f0a7d01e5502ea94f3 777 Gene3D G3DSA:1.10.101.10 77 152 0.002 T 28-03-2018 IPR002477 Peptidoglycan binding-like ALX04_RS15750 490e80c8a6f383f0a7d01e5502ea94f3 777 Gene3D G3DSA:1.10.101.10 219 297 8.6E-8 T 28-03-2018 IPR002477 Peptidoglycan binding-like ALX04_RS15750 490e80c8a6f383f0a7d01e5502ea94f3 777 SUPERFAMILY SSF47090 216 273 4.32E-7 T 28-03-2018 IPR002477 Peptidoglycan binding-like ALX04_RS15750 490e80c8a6f383f0a7d01e5502ea94f3 777 SUPERFAMILY SSF51445 299 482 6.6E-38 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily ALX04_RS15750 490e80c8a6f383f0a7d01e5502ea94f3 777 Gene3D G3DSA:3.20.20.80 298 518 1.3E-31 T 28-03-2018 ALX04_RS03855 00baa2b7476f82f739f4957865ec2b4c 314 SUPERFAMILY SSF52266 54 231 6.48E-34 T 28-03-2018 IPR013830 SGNH hydrolase-type esterase domain ALX04_RS03855 00baa2b7476f82f739f4957865ec2b4c 314 SUPERFAMILY SSF52266 268 305 6.48E-34 T 28-03-2018 IPR013830 SGNH hydrolase-type esterase domain ALX04_RS03855 00baa2b7476f82f739f4957865ec2b4c 314 Gene3D G3DSA:3.40.50.1110 50 313 1.9E-31 T 28-03-2018 ALX04_RS03855 00baa2b7476f82f739f4957865ec2b4c 314 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 61 295 1.2E-21 T 28-03-2018 IPR013830 SGNH hydrolase-type esterase domain ALX04_RS01945 85cba192277f0c98ec47fb3032e11de9 851 SUPERFAMILY SSF63520 408 500 1.22E-8 T 28-03-2018 IPR011608 PRD domain GO:0006355 ALX04_RS01945 85cba192277f0c98ec47fb3032e11de9 851 Gene3D G3DSA:3.40.50.510 511 638 2.0E-6 T 28-03-2018 IPR004701 Phosphotransferase system, mannose-type IIA component GO:0009401|GO:0016021 ALX04_RS01945 85cba192277f0c98ec47fb3032e11de9 851 Gene3D G3DSA:1.10.1790.10 737 851 6.6E-7 T 28-03-2018 IPR011608 PRD domain GO:0006355 ALX04_RS01945 85cba192277f0c98ec47fb3032e11de9 851 Gene3D G3DSA:3.40.50.300 75 257 2.0E-4 T 28-03-2018 ALX04_RS01945 85cba192277f0c98ec47fb3032e11de9 851 SUPERFAMILY SSF53062 514 607 5.23E-5 T 28-03-2018 IPR004701 Phosphotransferase system, mannose-type IIA component GO:0009401|GO:0016021 ALX04_RS01945 85cba192277f0c98ec47fb3032e11de9 851 Gene3D G3DSA:1.10.1790.10 385 501 8.5E-10 T 28-03-2018 IPR011608 PRD domain GO:0006355 ALX04_RS01945 85cba192277f0c98ec47fb3032e11de9 851 Gene3D G3DSA:1.10.10.10 1 70 2.1E-9 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS01945 85cba192277f0c98ec47fb3032e11de9 851 SUPERFAMILY SSF52540 74 298 8.39E-7 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase ALX04_RS01945 85cba192277f0c98ec47fb3032e11de9 851 SUPERFAMILY SSF63520 773 843 1.12E-5 T 28-03-2018 IPR011608 PRD domain GO:0006355 ALX04_RS01945 85cba192277f0c98ec47fb3032e11de9 851 Pfam PF00874 PRD domain 773 847 2.0E-5 T 28-03-2018 IPR011608 PRD domain GO:0006355 ALX04_RS01945 85cba192277f0c98ec47fb3032e11de9 851 Pfam PF00874 PRD domain 419 499 3.1E-8 T 28-03-2018 IPR011608 PRD domain GO:0006355 ALX04_RS15125 3960c90c40d27744e25570e5e4c2d70b 330 Gene3D G3DSA:3.40.50.720 1 117 1.1E-21 T 28-03-2018 ALX04_RS15125 3960c90c40d27744e25570e5e4c2d70b 330 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 4 329 7.6E-26 T 28-03-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0008152|GO:0016616|GO:0051287|GO:0055114 ALX04_RS15125 3960c90c40d27744e25570e5e4c2d70b 330 SUPERFAMILY SSF51735 104 301 3.5E-50 T 28-03-2018 IPR016040 NAD(P)-binding domain ALX04_RS15125 3960c90c40d27744e25570e5e4c2d70b 330 SUPERFAMILY SSF52283 2 137 7.87E-32 T 28-03-2018 ALX04_RS15125 3960c90c40d27744e25570e5e4c2d70b 330 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 113 299 2.8E-49 T 28-03-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 ALX04_RS15125 3960c90c40d27744e25570e5e4c2d70b 330 ProSitePatterns PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. 149 176 - T 28-03-2018 IPR029752 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 ALX04_RS15125 3960c90c40d27744e25570e5e4c2d70b 330 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 225 241 - T 28-03-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site ALX04_RS15125 3960c90c40d27744e25570e5e4c2d70b 330 Gene3D G3DSA:3.40.50.720 118 302 2.2E-50 T 28-03-2018 ALX04_RS05810 57287d8f7f56eaa987af520c88b1cac5 135 Gene3D G3DSA:2.40.50.140 2 85 1.7E-23 T 28-03-2018 ALX04_RS05810 57287d8f7f56eaa987af520c88b1cac5 135 SUPERFAMILY SSF50249 3 80 1.34E-21 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold ALX04_RS05810 57287d8f7f56eaa987af520c88b1cac5 135 SMART SM00316 7 78 1.8E-22 T 28-03-2018 IPR022967 RNA-binding domain, S1 ALX04_RS05810 57287d8f7f56eaa987af520c88b1cac5 135 Pfam PF00575 S1 RNA binding domain 7 78 4.8E-16 T 28-03-2018 IPR003029 S1 domain GO:0003676 ALX04_RS08815 38c4d30a43105b06c1b0f331e5fa45cd 610 Pfam PF09972 Predicted membrane protein (DUF2207) 34 535 3.9E-108 T 28-03-2018 IPR018702 Protein of unknown function DUF2207, membrane ALX04_RS08815 38c4d30a43105b06c1b0f331e5fa45cd 610 Gene3D G3DSA:2.60.40.1170 88 309 0.0014 T 28-03-2018 ALX04_RS04970 5b3d4b1bfb3f3387264d4a71a5b7f2b3 247 Pfam PF10552 ORF6C domain 127 235 1.0E-24 T 28-03-2018 IPR018878 ORF6C domain ALX04_RS04970 5b3d4b1bfb3f3387264d4a71a5b7f2b3 247 Pfam PF10543 ORF6N domain 10 93 6.8E-16 T 28-03-2018 IPR018873 KilA-N, DNA-binding domain ALX04_RS02650 c1987d083fb086bb2062a038279ea3dd 179 Gene3D G3DSA:1.10.4010.10 2 179 3.6E-25 T 28-03-2018 ALX04_RS02650 c1987d083fb086bb2062a038279ea3dd 179 Pfam PF08761 dUTPase 4 179 1.5E-19 T 28-03-2018 IPR014871 dUTPase/dCTP pyrophosphatase KEGG: 00240+3.6.1.12 ALX04_RS02650 c1987d083fb086bb2062a038279ea3dd 179 PIRSF PIRSF030140 2 179 1.1E-42 T 28-03-2018 IPR016947 Uncharacterised phage-associated protein UCP030140 ALX04_RS02650 c1987d083fb086bb2062a038279ea3dd 179 SUPERFAMILY SSF101386 1 179 5.67E-32 T 28-03-2018 ALX04_RS06530 61db8914e9a4647426cba408754ac6e9 576 ProSitePatterns PS00211 ABC transporters family signature. 469 483 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 ALX04_RS06530 61db8914e9a4647426cba408754ac6e9 576 Gene3D G3DSA:1.20.1560.10 1 314 1.1E-75 T 28-03-2018 ALX04_RS06530 61db8914e9a4647426cba408754ac6e9 576 SUPERFAMILY SSF90123 11 318 2.09E-71 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 ALX04_RS06530 61db8914e9a4647426cba408754ac6e9 576 SUPERFAMILY SSF52540 323 569 2.66E-73 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase ALX04_RS06530 61db8914e9a4647426cba408754ac6e9 576 Pfam PF00664 ABC transporter transmembrane region 15 285 5.0E-43 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 ALX04_RS06530 61db8914e9a4647426cba408754ac6e9 576 SMART SM00382 358 545 1.3E-13 T 28-03-2018 IPR003593 AAA+ ATPase domain ALX04_RS06530 61db8914e9a4647426cba408754ac6e9 576 Pfam PF00005 ABC transporter 349 495 1.2E-28 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 ALX04_RS06530 61db8914e9a4647426cba408754ac6e9 576 Gene3D G3DSA:3.40.50.300 317 575 9.1E-63 T 28-03-2018 ALX04_RS05830 4420ed51d5a861386defb7a44dbd7648 263 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 181 222 1.2E-5 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 ALX04_RS05830 4420ed51d5a861386defb7a44dbd7648 263 Pfam PF13344 Haloacid dehalogenase-like hydrolase 8 110 4.2E-21 T 28-03-2018 IPR006357 HAD-superfamily hydrolase, subfamily IIA ALX04_RS05830 4420ed51d5a861386defb7a44dbd7648 263 TIGRFAM TIGR01460 HAD-SF-IIA: HAD hydrolase, family IIA 8 231 1.2E-43 T 28-03-2018 IPR006357 HAD-superfamily hydrolase, subfamily IIA ALX04_RS05830 4420ed51d5a861386defb7a44dbd7648 263 SUPERFAMILY SSF56784 3 255 4.64E-65 T 28-03-2018 IPR023214 HAD-like domain ALX04_RS05830 4420ed51d5a861386defb7a44dbd7648 263 TIGRFAM TIGR01457 HAD-SF-IIA-hyp2: HAD hydrolase, TIGR01457 family 4 255 9.2E-94 T 28-03-2018 IPR006354 HAD-superfamily hydrolase, subfamily IIA, hypothetical 1 ALX04_RS05830 4420ed51d5a861386defb7a44dbd7648 263 Pfam PF13242 HAD-hyrolase-like 182 254 3.8E-18 T 28-03-2018 ALX04_RS05830 4420ed51d5a861386defb7a44dbd7648 263 Gene3D G3DSA:3.40.50.1000 1 255 4.4E-32 T 28-03-2018 IPR023214 HAD-like domain ALX04_RS14465 cd38a11e8b215e59edc72ad82bc36066 348 TIGRFAM TIGR03723 T6A_TsaD_YgjD: tRNA threonylcarbamoyl adenosine modification protein TsaD 10 322 1.4E-129 T 28-03-2018 IPR022450 tRNA N6-adenosine threonylcarbamoyltransferase, TsaD GO:0002949|GO:0004222 KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 ALX04_RS14465 cd38a11e8b215e59edc72ad82bc36066 348 SUPERFAMILY SSF53067 9 316 7.4E-42 T 28-03-2018 ALX04_RS14465 cd38a11e8b215e59edc72ad82bc36066 348 Hamap MF_01445 tRNA N6-adenosine threonylcarbamoyltransferase [tsaD]. 8 340 59.827 T 28-03-2018 IPR022450 tRNA N6-adenosine threonylcarbamoyltransferase, TsaD GO:0002949|GO:0004222 KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 ALX04_RS14465 cd38a11e8b215e59edc72ad82bc36066 348 ProSitePatterns PS01016 Glycoprotease family signature. 103 123 - T 28-03-2018 IPR017860 Peptidase M22, conserved site KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618|Reactome: R-HSA-6782315 ALX04_RS14465 cd38a11e8b215e59edc72ad82bc36066 348 Gene3D G3DSA:3.30.420.40 151 295 2.8E-17 T 28-03-2018 ALX04_RS14465 cd38a11e8b215e59edc72ad82bc36066 348 Pfam PF00814 Glycoprotease family 30 315 7.2E-103 T 28-03-2018 IPR000905 Gcp-like domain KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 ALX04_RS14465 cd38a11e8b215e59edc72ad82bc36066 348 Gene3D G3DSA:3.30.420.40 8 150 3.5E-43 T 28-03-2018 ALX04_RS14465 cd38a11e8b215e59edc72ad82bc36066 348 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 160 181 1.8E-47 T 28-03-2018 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 ALX04_RS14465 cd38a11e8b215e59edc72ad82bc36066 348 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 270 279 1.8E-47 T 28-03-2018 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 ALX04_RS14465 cd38a11e8b215e59edc72ad82bc36066 348 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 104 123 1.8E-47 T 28-03-2018 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 ALX04_RS14465 cd38a11e8b215e59edc72ad82bc36066 348 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 137 149 1.8E-47 T 28-03-2018 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 ALX04_RS14465 cd38a11e8b215e59edc72ad82bc36066 348 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 11 24 1.8E-47 T 28-03-2018 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 ALX04_RS14465 cd38a11e8b215e59edc72ad82bc36066 348 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 83 103 1.8E-47 T 28-03-2018 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 ALX04_RS14465 cd38a11e8b215e59edc72ad82bc36066 348 TIGRFAM TIGR00329 gcp_kae1: metallohydrolase, glycoprotease/Kae1 family 11 315 7.3E-107 T 28-03-2018 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 ALX04_RS01105 a77f72c97f65970490c4e40ecdb80446 242 Pfam PF10609 NUBPL iron-transfer P-loop NTPase 49 217 5.5E-13 T 28-03-2018 IPR033756 Flagellum site-determining protein YlxH/ Fe-S cluster assembling factor NBP35 ALX04_RS01105 a77f72c97f65970490c4e40ecdb80446 242 SUPERFAMILY SSF52540 48 227 1.48E-38 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase ALX04_RS01105 a77f72c97f65970490c4e40ecdb80446 242 Gene3D G3DSA:3.40.50.300 18 231 3.9E-39 T 28-03-2018 ALX04_RS01105 a77f72c97f65970490c4e40ecdb80446 242 TIGRFAM TIGR01007 eps_fam: capsular exopolysaccharide family 29 230 4.1E-57 T 28-03-2018 IPR005702 Exopolysaccharide synthesis protein GO:0045226 ALX04_RS01890 862449e8960505b137bd74b509363bad 579 SUPERFAMILY SSF50998 223 250 1.57E-6 T 28-03-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily ALX04_RS01890 862449e8960505b137bd74b509363bad 579 SUPERFAMILY SSF50998 291 461 1.57E-6 T 28-03-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily ALX04_RS01890 862449e8960505b137bd74b509363bad 579 Pfam PF05935 Arylsulfotransferase (ASST) 185 562 1.6E-81 T 28-03-2018 IPR010262 Arylsulfotransferase, C-terminal ALX04_RS01890 862449e8960505b137bd74b509363bad 579 Pfam PF17425 Arylsulfotransferase Ig-like domain 85 168 1.2E-20 T 28-03-2018 IPR035391 Arylsulfotransferase, Ig-like domain ALX04_RS01890 862449e8960505b137bd74b509363bad 579 Gene3D G3DSA:2.120.10.30 123 438 5.1E-5 T 28-03-2018 IPR011042 Six-bladed beta-propeller, TolB-like ALX04_RS15995 a3de77d259edcb713283f51d3f03aa54 463 Gene3D G3DSA:1.20.1250.20 250 458 4.4E-20 T 28-03-2018 ALX04_RS15995 a3de77d259edcb713283f51d3f03aa54 463 PRINTS PR01036 Tetracycline resistance protein TetB signature 300 324 6.2E-11 T 28-03-2018 ALX04_RS15995 a3de77d259edcb713283f51d3f03aa54 463 PRINTS PR01036 Tetracycline resistance protein TetB signature 396 415 6.2E-11 T 28-03-2018 ALX04_RS15995 a3de77d259edcb713283f51d3f03aa54 463 PRINTS PR01036 Tetracycline resistance protein TetB signature 161 185 6.2E-11 T 28-03-2018 ALX04_RS15995 a3de77d259edcb713283f51d3f03aa54 463 PRINTS PR01036 Tetracycline resistance protein TetB signature 136 160 6.2E-11 T 28-03-2018 ALX04_RS15995 a3de77d259edcb713283f51d3f03aa54 463 PRINTS PR01036 Tetracycline resistance protein TetB signature 15 39 6.2E-11 T 28-03-2018 ALX04_RS15995 a3de77d259edcb713283f51d3f03aa54 463 PRINTS PR01036 Tetracycline resistance protein TetB signature 106 126 6.2E-11 T 28-03-2018 ALX04_RS15995 a3de77d259edcb713283f51d3f03aa54 463 SUPERFAMILY SSF103473 11 201 1.7E-51 T 28-03-2018 IPR020846 Major facilitator superfamily domain ALX04_RS15995 a3de77d259edcb713283f51d3f03aa54 463 SUPERFAMILY SSF103473 247 453 1.7E-51 T 28-03-2018 IPR020846 Major facilitator superfamily domain ALX04_RS15995 a3de77d259edcb713283f51d3f03aa54 463 Pfam PF07690 Major Facilitator Superfamily 18 405 7.7E-36 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 ALX04_RS15995 a3de77d259edcb713283f51d3f03aa54 463 Gene3D G3DSA:1.20.1250.20 6 190 2.7E-24 T 28-03-2018 ALX04_RS04570 6616225967fbffe731178014c3f64843 389 Gene3D G3DSA:3.60.150.10 1 389 1.0E-124 T 28-03-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 ALX04_RS04570 6616225967fbffe731178014c3f64843 389 Hamap MF_00300 Chorismate synthase [aroC]. 2 371 32.521 T 28-03-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 ALX04_RS04570 6616225967fbffe731178014c3f64843 389 TIGRFAM TIGR00033 aroC: chorismate synthase 3 364 1.1E-116 T 28-03-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 ALX04_RS04570 6616225967fbffe731178014c3f64843 389 Pfam PF01264 Chorismate synthase 3 362 2.5E-110 T 28-03-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 ALX04_RS04570 6616225967fbffe731178014c3f64843 389 SUPERFAMILY SSF103263 3 388 5.63E-135 T 28-03-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 ALX04_RS04570 6616225967fbffe731178014c3f64843 389 PIRSF PIRSF001456 1 387 6.7E-126 T 28-03-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 ALX04_RS04570 6616225967fbffe731178014c3f64843 389 ProSitePatterns PS00787 Chorismate synthase signature 1. 8 23 - T 28-03-2018 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 ALX04_RS10745 eadaa6755ff94d763816cf734ed4f3f4 553 SUPERFAMILY SSF53795 234 542 1.06E-70 T 28-03-2018 ALX04_RS10745 eadaa6755ff94d763816cf734ed4f3f4 553 Pfam PF01293 Phosphoenolpyruvate carboxykinase 73 478 5.2E-22 T 28-03-2018 IPR001272 Phosphoenolpyruvate carboxykinase, ATP-utilising GO:0004612|GO:0005524|GO:0006094 KEGG: 00010+4.1.1.49|KEGG: 00020+4.1.1.49|KEGG: 00620+4.1.1.49|KEGG: 00710+4.1.1.49|MetaCyc: PWY-561|MetaCyc: PWY-7117 ALX04_RS10745 eadaa6755ff94d763816cf734ed4f3f4 553 SUPERFAMILY SSF68923 53 232 1.06E-36 T 28-03-2018 IPR008210 Phosphoenolpyruvate carboxykinase, N-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 ALX04_RS10745 eadaa6755ff94d763816cf734ed4f3f4 553 Gene3D G3DSA:3.40.449.10 63 232 7.1E-28 T 28-03-2018 IPR008210 Phosphoenolpyruvate carboxykinase, N-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 ALX04_RS10745 eadaa6755ff94d763816cf734ed4f3f4 553 Gene3D G3DSA:3.90.228.20 328 551 9.3E-37 T 28-03-2018 IPR013035 Phosphoenolpyruvate carboxykinase, C-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 ALX04_RS10745 eadaa6755ff94d763816cf734ed4f3f4 553 Gene3D G3DSA:3.90.228.20 234 327 7.3E-12 T 28-03-2018 IPR013035 Phosphoenolpyruvate carboxykinase, C-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 ALX04_RS02060 b82bbcb1c3ddda146e5d078d2c944630 812 Gene3D G3DSA:3.50.50.60 283 630 4.0E-47 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ALX04_RS02060 b82bbcb1c3ddda146e5d078d2c944630 812 Gene3D G3DSA:3.90.700.10 631 739 1.4E-31 T 28-03-2018 ALX04_RS02060 b82bbcb1c3ddda146e5d078d2c944630 812 SUPERFAMILY SSF51905 292 353 2.26E-53 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ALX04_RS02060 b82bbcb1c3ddda146e5d078d2c944630 812 SUPERFAMILY SSF51905 747 804 2.26E-53 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ALX04_RS02060 b82bbcb1c3ddda146e5d078d2c944630 812 SUPERFAMILY SSF51905 409 609 2.26E-53 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ALX04_RS02060 b82bbcb1c3ddda146e5d078d2c944630 812 SUPERFAMILY SSF56425 594 744 2.09E-33 T 28-03-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 ALX04_RS02060 b82bbcb1c3ddda146e5d078d2c944630 812 Pfam PF04205 FMN-binding domain 201 272 1.6E-11 T 28-03-2018 IPR007329 FMN-binding GO:0010181|GO:0016020 ALX04_RS02060 b82bbcb1c3ddda146e5d078d2c944630 812 TIGRFAM TIGR01813 flavo_cyto_c: flavocytochrome c 427 799 8.9E-88 T 28-03-2018 IPR010960 Flavocytochrome c GO:0000104|GO:0055114 ALX04_RS02060 b82bbcb1c3ddda146e5d078d2c944630 812 Pfam PF03358 NADPH-dependent FMN reductase 1 146 1.1E-32 T 28-03-2018 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 ALX04_RS02060 b82bbcb1c3ddda146e5d078d2c944630 812 Pfam PF00890 FAD binding domain 302 352 1.4E-11 T 28-03-2018 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 ALX04_RS02060 b82bbcb1c3ddda146e5d078d2c944630 812 Pfam PF00890 FAD binding domain 409 788 4.5E-57 T 28-03-2018 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 ALX04_RS02060 b82bbcb1c3ddda146e5d078d2c944630 812 Gene3D G3DSA:3.40.50.360 1 179 2.7E-27 T 28-03-2018 IPR029039 Flavoprotein-like domain ALX04_RS02060 b82bbcb1c3ddda146e5d078d2c944630 812 SMART SM00900 201 275 1.1E-18 T 28-03-2018 IPR007329 FMN-binding GO:0010181|GO:0016020 ALX04_RS02060 b82bbcb1c3ddda146e5d078d2c944630 812 SUPERFAMILY SSF52218 1 172 9.58E-37 T 28-03-2018 IPR029039 Flavoprotein-like domain ALX04_RS05445 34fa08eeda3484ec1106c6e5ca4b9858 230 Gene3D G3DSA:3.40.50.1580 1 229 1.3E-53 T 28-03-2018 ALX04_RS05445 34fa08eeda3484ec1106c6e5ca4b9858 230 Pfam PF01048 Phosphorylase superfamily 2 225 4.2E-47 T 28-03-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 ALX04_RS05445 34fa08eeda3484ec1106c6e5ca4b9858 230 SUPERFAMILY SSF53167 1 225 2.36E-69 T 28-03-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 ALX04_RS05445 34fa08eeda3484ec1106c6e5ca4b9858 230 TIGRFAM TIGR01704 MTA/SAH-Nsdase: MTA/SAH nucleosidase 2 225 8.4E-71 T 28-03-2018 IPR010049 MTA/SAH nucleosidase GO:0008782|GO:0008930|GO:0009164|GO:0019509 KEGG: 00270+3.2.2.9|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 ALX04_RS11855 3507e4261dd53b6e68e5b045e8a082b8 478 Gene3D G3DSA:1.20.140.10 275 470 1.5E-47 T 28-03-2018 ALX04_RS11855 3507e4261dd53b6e68e5b045e8a082b8 478 Pfam PF03241 4-hydroxyphenylacetate 3-hydroxylase C terminal 272 469 1.0E-42 T 28-03-2018 IPR024719 HpaB/PvcC/4-BUDH C-terminal ALX04_RS11855 3507e4261dd53b6e68e5b045e8a082b8 478 Gene3D G3DSA:2.40.110.10 135 266 1.2E-12 T 28-03-2018 ALX04_RS11855 3507e4261dd53b6e68e5b045e8a082b8 478 Pfam PF11794 4-hydroxyphenylacetate 3-hydroxylase N terminal 4 264 2.8E-71 T 28-03-2018 IPR024674 HpaB/PvcC/4-BUDH N-terminal ALX04_RS11855 3507e4261dd53b6e68e5b045e8a082b8 478 SUPERFAMILY SSF47203 256 470 3.77E-48 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 ALX04_RS11855 3507e4261dd53b6e68e5b045e8a082b8 478 PIRSF PIRSF000331 2 478 3.6E-108 T 28-03-2018 IPR004925 HpaB/PvcC/4-BUDH ALX04_RS11855 3507e4261dd53b6e68e5b045e8a082b8 478 SUPERFAMILY SSF56645 4 264 1.03E-55 T 28-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 ALX04_RS11855 3507e4261dd53b6e68e5b045e8a082b8 478 Gene3D G3DSA:1.10.3140.10 3 134 2.2E-31 T 28-03-2018 ALX04_RS01330 c42a6e0127aa98a61a548283322cbdd1 525 Pfam PF03144 Elongation factor Tu domain 2 314 380 1.3E-11 T 28-03-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 ALX04_RS01330 c42a6e0127aa98a61a548283322cbdd1 525 Hamap MF_00072 Peptide chain release factor 3 [prfC]. 4 525 49.235 T 28-03-2018 IPR004548 Peptide chain release factor 3 GO:0003924|GO:0005737|GO:0006415 ALX04_RS01330 c42a6e0127aa98a61a548283322cbdd1 525 Gene3D G3DSA:2.40.30.10 274 391 1.9E-23 T 28-03-2018 ALX04_RS01330 c42a6e0127aa98a61a548283322cbdd1 525 Pfam PF16658 Class II release factor RF3, C-terminal domain 388 512 6.8E-43 T 28-03-2018 IPR032090 Peptide chain release factor 3, C-terminal ALX04_RS01330 c42a6e0127aa98a61a548283322cbdd1 525 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 17 159 2.5E-20 T 28-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 ALX04_RS01330 c42a6e0127aa98a61a548283322cbdd1 525 Gene3D G3DSA:3.40.50.300 8 273 4.0E-38 T 28-03-2018 ALX04_RS01330 c42a6e0127aa98a61a548283322cbdd1 525 Pfam PF00009 Elongation factor Tu GTP binding domain 13 276 9.0E-49 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 ALX04_RS01330 c42a6e0127aa98a61a548283322cbdd1 525 SUPERFAMILY SSF50447 260 389 2.03E-28 T 28-03-2018 IPR009000 Translation protein, beta-barrel domain ALX04_RS01330 c42a6e0127aa98a61a548283322cbdd1 525 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 58 73 - T 28-03-2018 IPR031157 Tr-type G domain, conserved site ALX04_RS01330 c42a6e0127aa98a61a548283322cbdd1 525 SUPERFAMILY SSF52540 11 276 1.76E-85 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase ALX04_RS01330 c42a6e0127aa98a61a548283322cbdd1 525 Gene3D G3DSA:3.30.70.870 394 466 3.5E-11 T 28-03-2018 ALX04_RS01330 c42a6e0127aa98a61a548283322cbdd1 525 TIGRFAM TIGR00503 prfC: peptide chain release factor 3 8 522 3.5E-203 T 28-03-2018 IPR004548 Peptide chain release factor 3 GO:0003924|GO:0005737|GO:0006415 ALX04_RS01330 c42a6e0127aa98a61a548283322cbdd1 525 PRINTS PR00315 GTP-binding elongation factor signature 15 28 1.1E-10 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 ALX04_RS01330 c42a6e0127aa98a61a548283322cbdd1 525 PRINTS PR00315 GTP-binding elongation factor signature 137 146 1.1E-10 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 ALX04_RS01330 c42a6e0127aa98a61a548283322cbdd1 525 PRINTS PR00315 GTP-binding elongation factor signature 85 95 1.1E-10 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 ALX04_RS01330 c42a6e0127aa98a61a548283322cbdd1 525 PRINTS PR00315 GTP-binding elongation factor signature 65 73 1.1E-10 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 ALX04_RS01330 c42a6e0127aa98a61a548283322cbdd1 525 PRINTS PR00315 GTP-binding elongation factor signature 101 112 1.1E-10 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 ALX04_RS01330 c42a6e0127aa98a61a548283322cbdd1 525 SUPERFAMILY SSF54980 394 466 1.4E-15 T 28-03-2018 IPR035647 EF-G domain III/V-like ALX04_RS00360 79dbff680b32c85612ee9b4d465e8244 137 PIRSF PIRSF002133 1 137 8.9E-48 T 28-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 ALX04_RS00360 79dbff680b32c85612ee9b4d465e8244 137 Hamap MF_00403_B 30S ribosomal protein S12 [rpsL]. 1 136 39.574 T 28-03-2018 IPR005679 Ribosomal protein S12, bacterial-type GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 ALX04_RS00360 79dbff680b32c85612ee9b4d465e8244 137 ProSitePatterns PS00055 Ribosomal protein S12 signature. 56 63 - T 28-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 ALX04_RS00360 79dbff680b32c85612ee9b4d465e8244 137 TIGRFAM TIGR00981 rpsL_bact: ribosomal protein uS12 1 137 2.2E-66 T 28-03-2018 IPR005679 Ribosomal protein S12, bacterial-type GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 ALX04_RS00360 79dbff680b32c85612ee9b4d465e8244 137 Gene3D G3DSA:2.40.50.140 1 137 3.7E-62 T 28-03-2018 ALX04_RS00360 79dbff680b32c85612ee9b4d465e8244 137 Pfam PF00164 Ribosomal protein S12/S23 32 136 1.4E-36 T 28-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 ALX04_RS00360 79dbff680b32c85612ee9b4d465e8244 137 SUPERFAMILY SSF50249 2 136 3.26E-47 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold ALX04_RS00360 79dbff680b32c85612ee9b4d465e8244 137 PRINTS PR01034 Ribosomal protein S12 signature 40 55 2.7E-57 T 28-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 ALX04_RS00360 79dbff680b32c85612ee9b4d465e8244 137 PRINTS PR01034 Ribosomal protein S12 signature 107 123 2.7E-57 T 28-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 ALX04_RS00360 79dbff680b32c85612ee9b4d465e8244 137 PRINTS PR01034 Ribosomal protein S12 signature 71 90 2.7E-57 T 28-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 ALX04_RS00360 79dbff680b32c85612ee9b4d465e8244 137 PRINTS PR01034 Ribosomal protein S12 signature 55 70 2.7E-57 T 28-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 ALX04_RS00360 79dbff680b32c85612ee9b4d465e8244 137 PRINTS PR01034 Ribosomal protein S12 signature 123 135 2.7E-57 T 28-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 ALX04_RS00360 79dbff680b32c85612ee9b4d465e8244 137 PRINTS PR01034 Ribosomal protein S12 signature 90 107 2.7E-57 T 28-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 ALX04_RS09475 1069572c37167a55ce5445785175b3db 322 SUPERFAMILY SSF51735 124 276 2.11E-27 T 28-03-2018 IPR016040 NAD(P)-binding domain ALX04_RS09475 1069572c37167a55ce5445785175b3db 322 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 29 87 1.6E-5 T 28-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 ALX04_RS09475 1069572c37167a55ce5445785175b3db 322 SUPERFAMILY SSF50129 1 142 4.11E-29 T 28-03-2018 IPR011032 GroES-like ALX04_RS09475 1069572c37167a55ce5445785175b3db 322 Gene3D G3DSA:3.40.50.720 141 262 4.0E-20 T 28-03-2018 ALX04_RS09475 1069572c37167a55ce5445785175b3db 322 Pfam PF00107 Zinc-binding dehydrogenase 155 274 6.7E-14 T 28-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 ALX04_RS09475 1069572c37167a55ce5445785175b3db 322 SMART SM00829 10 319 2.3E-4 T 28-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 ALX04_RS09475 1069572c37167a55ce5445785175b3db 322 Gene3D G3DSA:3.90.180.10 1 140 5.4E-31 T 28-03-2018 ALX04_RS13655 f32fa36e42d5d7b6f0601c0b764608a2 242 Pfam PF08348 YheO-like PAS domain 14 124 4.6E-34 T 28-03-2018 IPR013559 YheO-like ALX04_RS13655 f32fa36e42d5d7b6f0601c0b764608a2 242 Gene3D G3DSA:1.10.10.60 189 241 6.3E-8 T 28-03-2018 ALX04_RS13655 f32fa36e42d5d7b6f0601c0b764608a2 242 Pfam PF13309 HTH domain 172 231 1.0E-19 T 28-03-2018 ALX04_RS13655 f32fa36e42d5d7b6f0601c0b764608a2 242 ProDom PD037769 DNA-BINDING YHEO UNCHARACTERIZED BACTERIA SIMILAR HI0575 CONTAINING TRANSCRIPTION REGULATOR HELIX-TURN-HELIX 10 130 5.0E-66 T 28-03-2018 IPR013559 YheO-like ALX04_RS13585 f0c022fa290bacb3175227ce8236aedd 326 SMART SM01400 10 126 5.5E-83 T 28-03-2018 ALX04_RS13585 f0c022fa290bacb3175227ce8236aedd 326 Pfam PF14572 Phosphoribosyl synthetase-associated domain 209 318 5.5E-23 T 28-03-2018 IPR005946 Ribose-phosphate diphosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 ALX04_RS13585 f0c022fa290bacb3175227ce8236aedd 326 ProSitePatterns PS00114 Phosphoribosyl pyrophosphate synthase signature. 134 149 - T 28-03-2018 IPR000842 Phosphoribosyl pyrophosphate synthetase, conserved site GO:0000287|GO:0004749|GO:0009156|GO:0044249 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1|Reactome: R-HSA-73843 ALX04_RS13585 f0c022fa290bacb3175227ce8236aedd 326 Hamap MF_00583_B Ribose-phosphate pyrophosphokinase [prs]. 10 318 50.305 T 28-03-2018 IPR005946 Ribose-phosphate diphosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 ALX04_RS13585 f0c022fa290bacb3175227ce8236aedd 326 Pfam PF13793 N-terminal domain of ribose phosphate pyrophosphokinase 10 126 5.2E-53 T 28-03-2018 IPR029099 Ribose-phosphate pyrophosphokinase, N-terminal domain KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 ALX04_RS13585 f0c022fa290bacb3175227ce8236aedd 326 TIGRFAM TIGR01251 ribP_PPkin: ribose-phosphate diphosphokinase 11 318 6.9E-124 T 28-03-2018 IPR005946 Ribose-phosphate diphosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 ALX04_RS13585 f0c022fa290bacb3175227ce8236aedd 326 Gene3D G3DSA:3.40.50.2020 10 153 1.2E-66 T 28-03-2018 ALX04_RS13585 f0c022fa290bacb3175227ce8236aedd 326 Gene3D G3DSA:3.40.50.2020 154 319 7.9E-44 T 28-03-2018 ALX04_RS13585 f0c022fa290bacb3175227ce8236aedd 326 SUPERFAMILY SSF53271 75 309 2.79E-63 T 28-03-2018 IPR029057 Phosphoribosyltransferase-like ALX04_RS15685 7bb58c11ad29668a6b95e68ac77b30b9 123 Pfam PF05973 Phage derived protein Gp49-like (DUF891) 20 110 1.5E-19 T 28-03-2018 IPR009241 Toxin HigB-like ALX04_RS13120 7f7e4af62b068856027a2afb40c655a7 222 Gene3D G3DSA:3.30.70.260 136 198 1.8E-16 T 28-03-2018 ALX04_RS13120 7f7e4af62b068856027a2afb40c655a7 222 SUPERFAMILY SSF75445 125 201 3.01E-16 T 28-03-2018 ALX04_RS13120 7f7e4af62b068856027a2afb40c655a7 222 TIGRFAM TIGR00021 rpiA: ribose 5-phosphate isomerase A 4 213 1.2E-42 T 28-03-2018 IPR004788 Ribose 5-phosphate isomerase, type A GO:0004751|GO:0009052 KEGG: 00030+5.3.1.6|KEGG: 00051+5.3.1.6|KEGG: 00710+5.3.1.6|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 ALX04_RS13120 7f7e4af62b068856027a2afb40c655a7 222 Gene3D G3DSA:3.40.50.1360 1 135 9.2E-30 T 28-03-2018 ALX04_RS13120 7f7e4af62b068856027a2afb40c655a7 222 Pfam PF06026 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) 45 213 2.7E-40 T 28-03-2018 IPR004788 Ribose 5-phosphate isomerase, type A GO:0004751|GO:0009052 KEGG: 00030+5.3.1.6|KEGG: 00051+5.3.1.6|KEGG: 00710+5.3.1.6|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 ALX04_RS13120 7f7e4af62b068856027a2afb40c655a7 222 SUPERFAMILY SSF100950 2 142 7.95E-31 T 28-03-2018 ALX04_RS08855 6ac4086bf0137483feab96b39c493ded 276 Pfam PF07859 alpha/beta hydrolase fold 42 181 1.2E-11 T 28-03-2018 IPR013094 Alpha/beta hydrolase fold-3 GO:0008152|GO:0016787 ALX04_RS08855 6ac4086bf0137483feab96b39c493ded 276 Gene3D G3DSA:3.40.50.1820 1 276 4.1E-33 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold ALX04_RS08855 6ac4086bf0137483feab96b39c493ded 276 SUPERFAMILY SSF53474 33 258 3.64E-31 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold ALX04_RS10060 b3b9fa46d1db9969faee35a069160580 634 Gene3D G3DSA:3.40.50.2300 400 488 1.9E-15 T 28-03-2018 ALX04_RS10060 b3b9fa46d1db9969faee35a069160580 634 Gene3D G3DSA:1.10.10.10 11 70 9.3E-9 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS10060 b3b9fa46d1db9969faee35a069160580 634 Gene3D G3DSA:1.10.10.10 82 156 4.5E-10 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS10060 b3b9fa46d1db9969faee35a069160580 634 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 497 633 1.1E-24 T 28-03-2018 IPR002178 PTS EIIA type-2 domain ALX04_RS10060 b3b9fa46d1db9969faee35a069160580 634 SUPERFAMILY SSF52794 404 474 1.62E-7 T 28-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 ALX04_RS10060 b3b9fa46d1db9969faee35a069160580 634 Pfam PF00874 PRD domain 202 286 8.1E-12 T 28-03-2018 IPR011608 PRD domain GO:0006355 ALX04_RS10060 b3b9fa46d1db9969faee35a069160580 634 Pfam PF00874 PRD domain 314 389 4.6E-19 T 28-03-2018 IPR011608 PRD domain GO:0006355 ALX04_RS10060 b3b9fa46d1db9969faee35a069160580 634 Gene3D G3DSA:1.10.1790.10 157 291 1.2E-12 T 28-03-2018 IPR011608 PRD domain GO:0006355 ALX04_RS10060 b3b9fa46d1db9969faee35a069160580 634 Gene3D G3DSA:1.10.1790.10 293 394 9.5E-22 T 28-03-2018 IPR011608 PRD domain GO:0006355 ALX04_RS10060 b3b9fa46d1db9969faee35a069160580 634 SUPERFAMILY SSF63520 191 287 2.35E-13 T 28-03-2018 IPR011608 PRD domain GO:0006355 ALX04_RS10060 b3b9fa46d1db9969faee35a069160580 634 SUPERFAMILY SSF63520 293 394 5.62E-23 T 28-03-2018 IPR011608 PRD domain GO:0006355 ALX04_RS10060 b3b9fa46d1db9969faee35a069160580 634 SUPERFAMILY SSF55804 494 633 7.33E-28 T 28-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 ALX04_RS10060 b3b9fa46d1db9969faee35a069160580 634 Gene3D G3DSA:3.40.930.10 492 634 3.8E-28 T 28-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 ALX04_RS10060 b3b9fa46d1db9969faee35a069160580 634 SUPERFAMILY SSF46785 90 143 9.37E-6 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS10060 b3b9fa46d1db9969faee35a069160580 634 Pfam PF08279 HTH domain 92 141 1.6E-4 T 28-03-2018 IPR013196 Helix-turn-helix, type 11 ALX04_RS00285 c39f92a72806a5219c90c96ac0d53b86 211 PIRSF PIRSF000705 1 211 1.8E-53 T 28-03-2018 IPR002624 Deoxynucleoside kinase GO:0005524|GO:0006139|GO:0019206 ALX04_RS00285 c39f92a72806a5219c90c96ac0d53b86 211 Gene3D G3DSA:3.40.50.300 1 207 1.5E-38 T 28-03-2018 ALX04_RS00285 c39f92a72806a5219c90c96ac0d53b86 211 Pfam PF01712 Deoxynucleoside kinase 2 207 4.1E-57 T 28-03-2018 IPR031314 Deoxynucleoside kinase domain ALX04_RS00285 c39f92a72806a5219c90c96ac0d53b86 211 SUPERFAMILY SSF52540 3 207 3.26E-41 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase ALX04_RS01785 6e5ae153248e60d9d6c6ba0a6e36162c 255 Gene3D G3DSA:3.40.50.2300 2 146 1.0E-12 T 28-03-2018 ALX04_RS01785 6e5ae153248e60d9d6c6ba0a6e36162c 255 Pfam PF00072 Response regulator receiver domain 5 124 1.1E-12 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 ALX04_RS01785 6e5ae153248e60d9d6c6ba0a6e36162c 255 SMART SM00850 152 246 1.6E-9 T 28-03-2018 IPR007492 LytTR DNA-binding domain GO:0003677 ALX04_RS01785 6e5ae153248e60d9d6c6ba0a6e36162c 255 SMART SM00448 2 124 1.5E-10 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 ALX04_RS01785 6e5ae153248e60d9d6c6ba0a6e36162c 255 Pfam PF04397 LytTr DNA-binding domain 153 245 6.3E-11 T 28-03-2018 IPR007492 LytTR DNA-binding domain GO:0003677 ALX04_RS01785 6e5ae153248e60d9d6c6ba0a6e36162c 255 Gene3D G3DSA:2.40.50.40 147 211 9.7E-9 T 28-03-2018 ALX04_RS01785 6e5ae153248e60d9d6c6ba0a6e36162c 255 SUPERFAMILY SSF52172 4 132 7.68E-12 T 28-03-2018 IPR011006 CheY-like superfamily ALX04_RS10630 c3d7d694ac6e0f5299274d96684cc293 312 SUPERFAMILY SSF53474 54 312 1.05E-42 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold ALX04_RS10630 c3d7d694ac6e0f5299274d96684cc293 312 Pfam PF12146 Serine aminopeptidase, S33 90 191 2.2E-11 T 28-03-2018 IPR022742 Serine aminopeptidase, S33 ALX04_RS10630 c3d7d694ac6e0f5299274d96684cc293 312 Gene3D G3DSA:3.40.50.1820 39 312 3.0E-40 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold ALX04_RS00095 7899928b37d1e81cdccc0ced1d2728eb 254 SUPERFAMILY SSF52218 2 183 1.5E-26 T 28-03-2018 IPR029039 Flavoprotein-like domain ALX04_RS00095 7899928b37d1e81cdccc0ced1d2728eb 254 Pfam PF03358 NADPH-dependent FMN reductase 2 92 2.9E-19 T 28-03-2018 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 ALX04_RS00095 7899928b37d1e81cdccc0ced1d2728eb 254 Gene3D G3DSA:3.40.50.360 1 193 8.0E-27 T 28-03-2018 IPR029039 Flavoprotein-like domain ALX04_RS12940 1732bcfaad100f12b440452dd061d9a5 140 SMART SM00347 21 121 1.9E-11 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 ALX04_RS12940 1732bcfaad100f12b440452dd061d9a5 140 Pfam PF01047 MarR family 28 84 2.9E-9 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 ALX04_RS12940 1732bcfaad100f12b440452dd061d9a5 140 Gene3D G3DSA:1.10.10.10 3 136 6.0E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS12940 1732bcfaad100f12b440452dd061d9a5 140 SUPERFAMILY SSF46785 6 138 3.72E-27 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS10155 e565002949e20dd33475872c1f653682 498 TIGRFAM TIGR02734 crtI_fam: phytoene desaturase 5 495 5.6E-133 T 28-03-2018 IPR014105 Carotenoid/retinoid oxidoreductase GO:0016117|GO:0055114 ALX04_RS10155 e565002949e20dd33475872c1f653682 498 PRINTS PR00419 Adrenodoxin reductase family signature 26 39 7.6E-6 T 28-03-2018 ALX04_RS10155 e565002949e20dd33475872c1f653682 498 PRINTS PR00419 Adrenodoxin reductase family signature 3 25 7.6E-6 T 28-03-2018 ALX04_RS10155 e565002949e20dd33475872c1f653682 498 Gene3D G3DSA:3.50.50.60 1 318 1.9E-27 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ALX04_RS10155 e565002949e20dd33475872c1f653682 498 SUPERFAMILY SSF51905 1 319 8.55E-69 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ALX04_RS10155 e565002949e20dd33475872c1f653682 498 SUPERFAMILY SSF51905 452 492 8.55E-69 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ALX04_RS10155 e565002949e20dd33475872c1f653682 498 Pfam PF01593 Flavin containing amine oxidoreductase 11 491 2.7E-26 T 28-03-2018 IPR002937 Amine oxidase GO:0016491|GO:0055114 ALX04_RS00035 3bc11d2420089349b096b761efa8c963 629 Pfam PF04205 FMN-binding domain 548 619 7.3E-12 T 28-03-2018 IPR007329 FMN-binding GO:0010181|GO:0016020 ALX04_RS00035 3bc11d2420089349b096b761efa8c963 629 SUPERFAMILY SSF56425 285 437 1.36E-22 T 28-03-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 ALX04_RS00035 3bc11d2420089349b096b761efa8c963 629 SUPERFAMILY SSF51905 437 494 4.72E-29 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ALX04_RS00035 3bc11d2420089349b096b761efa8c963 629 SUPERFAMILY SSF51905 14 275 4.72E-29 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ALX04_RS00035 3bc11d2420089349b096b761efa8c963 629 Pfam PF00890 FAD binding domain 23 476 2.1E-34 T 28-03-2018 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 ALX04_RS00035 3bc11d2420089349b096b761efa8c963 629 SMART SM00900 548 622 2.3E-16 T 28-03-2018 IPR007329 FMN-binding GO:0010181|GO:0016020 ALX04_RS00035 3bc11d2420089349b096b761efa8c963 629 Gene3D G3DSA:3.50.50.60 17 493 6.8E-40 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ALX04_RS14665 f20876549761614607c28b355519f315 398 ProSitePatterns PS00216 Sugar transport proteins signature 1. 62 78 - T 28-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 ALX04_RS14665 f20876549761614607c28b355519f315 398 Gene3D G3DSA:1.20.1250.20 1 194 2.1E-41 T 28-03-2018 ALX04_RS14665 f20876549761614607c28b355519f315 398 Gene3D G3DSA:1.20.1250.20 198 397 5.4E-25 T 28-03-2018 ALX04_RS14665 f20876549761614607c28b355519f315 398 PRINTS PR01035 Tetracycline resistance protein signature 161 181 3.6E-22 T 28-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 ALX04_RS14665 f20876549761614607c28b355519f315 398 PRINTS PR01035 Tetracycline resistance protein signature 75 99 3.6E-22 T 28-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 ALX04_RS14665 f20876549761614607c28b355519f315 398 PRINTS PR01035 Tetracycline resistance protein signature 338 361 3.6E-22 T 28-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 ALX04_RS14665 f20876549761614607c28b355519f315 398 PRINTS PR01035 Tetracycline resistance protein signature 133 155 3.6E-22 T 28-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 ALX04_RS14665 f20876549761614607c28b355519f315 398 PRINTS PR01035 Tetracycline resistance protein signature 18 34 3.6E-22 T 28-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 ALX04_RS14665 f20876549761614607c28b355519f315 398 Pfam PF07690 Major Facilitator Superfamily 13 266 4.3E-46 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 ALX04_RS14665 f20876549761614607c28b355519f315 398 SUPERFAMILY SSF103473 1 392 1.26E-73 T 28-03-2018 IPR020846 Major facilitator superfamily domain ALX04_RS11280 2df8ba3abd1967b2d988a8c53b259096 255 SUPERFAMILY SSF100950 75 236 1.16E-30 T 28-03-2018 ALX04_RS11280 2df8ba3abd1967b2d988a8c53b259096 255 Pfam PF00455 DeoR C terminal sensor domain 75 234 5.5E-47 T 28-03-2018 IPR014036 DeoR C-terminal sensor domain ALX04_RS11280 2df8ba3abd1967b2d988a8c53b259096 255 Gene3D G3DSA:3.40.50.1360 64 238 2.1E-36 T 28-03-2018 ALX04_RS11280 2df8ba3abd1967b2d988a8c53b259096 255 ProSitePatterns PS00894 DeoR-type HTH domain signature. 6 40 - T 28-03-2018 IPR018356 Transcription regulator, HTH DeoR-type, conserved site GO:0003700|GO:0006355 ALX04_RS11280 2df8ba3abd1967b2d988a8c53b259096 255 Gene3D G3DSA:1.10.10.10 1 59 1.0E-13 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS11280 2df8ba3abd1967b2d988a8c53b259096 255 Pfam PF08220 DeoR-like helix-turn-helix domain 6 61 1.4E-13 T 28-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 ALX04_RS11280 2df8ba3abd1967b2d988a8c53b259096 255 SMART SM00420 6 58 5.9E-12 T 28-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 ALX04_RS11280 2df8ba3abd1967b2d988a8c53b259096 255 SUPERFAMILY SSF46785 5 72 1.4E-12 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS11280 2df8ba3abd1967b2d988a8c53b259096 255 SMART SM01134 72 235 3.8E-62 T 28-03-2018 ALX04_RS11860 198362df8023b00481113102c1f4c663 149 SMART SM01022 26 146 1.3E-37 T 28-03-2018 IPR007374 ASCH domain ALX04_RS11860 198362df8023b00481113102c1f4c663 149 PIRSF PIRSF021320 1 149 4.9E-56 T 28-03-2018 IPR009326 Protein of unknown function DUF984 ALX04_RS11860 198362df8023b00481113102c1f4c663 149 Gene3D G3DSA:3.10.400.10 2 148 6.1E-49 T 28-03-2018 ALX04_RS11860 198362df8023b00481113102c1f4c663 149 Pfam PF04266 ASCH domain 34 146 2.3E-19 T 28-03-2018 IPR007374 ASCH domain ALX04_RS11860 198362df8023b00481113102c1f4c663 149 SUPERFAMILY SSF88697 2 148 3.73E-50 T 28-03-2018 IPR015947 PUA-like domain ALX04_RS07650 2027222a9ca86a07472d456a77e25615 788 Pfam PF03894 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase 398 573 2.1E-79 T 28-03-2018 IPR005593 Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase GO:0005975|GO:0016832 ALX04_RS07650 2027222a9ca86a07472d456a77e25615 788 Pfam PF09363 XFP C-terminal domain 584 784 4.7E-82 T 28-03-2018 IPR018969 Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase, C-terminal GO:0005975|GO:0016832 ALX04_RS07650 2027222a9ca86a07472d456a77e25615 788 Hamap MF_01403 Probable phosphoketolase. 3 786 39.867 T 28-03-2018 IPR023962 Probable phosphoketolase ALX04_RS07650 2027222a9ca86a07472d456a77e25615 788 SUPERFAMILY SSF52518 374 590 7.36E-34 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold ALX04_RS07650 2027222a9ca86a07472d456a77e25615 788 Pfam PF09364 XFP N-terminal domain 7 383 1.7E-183 T 28-03-2018 IPR018970 Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase, N-terminal ALX04_RS07650 2027222a9ca86a07472d456a77e25615 788 ProSitePatterns PS60003 Phosphoketolase signature 2. 155 173 - T 28-03-2018 IPR019789 Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase, thiamine diphosphate binding site GO:0005975|GO:0016832 ALX04_RS07650 2027222a9ca86a07472d456a77e25615 788 Gene3D G3DSA:3.40.50.970 375 599 6.9E-30 T 28-03-2018 ALX04_RS07650 2027222a9ca86a07472d456a77e25615 788 Gene3D G3DSA:3.40.50.970 1 374 7.8E-86 T 28-03-2018 ALX04_RS07650 2027222a9ca86a07472d456a77e25615 788 ProSitePatterns PS60002 Phosphoketolase signature 1. 142 148 - T 28-03-2018 IPR019790 Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase, conserved site GO:0005975|GO:0016832 ALX04_RS07650 2027222a9ca86a07472d456a77e25615 788 PIRSF PIRSF017245 1 786 0.0 T 28-03-2018 IPR005593 Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase GO:0005975|GO:0016832 ALX04_RS07650 2027222a9ca86a07472d456a77e25615 788 SUPERFAMILY SSF52518 3 366 2.55E-70 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold ALX04_RS07650 2027222a9ca86a07472d456a77e25615 788 Gene3D G3DSA:3.40.50.920 604 786 1.6E-68 T 28-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 ALX04_RS06970 46a797bb0fe1857f08c22af298603838 188 Pfam PF01381 Helix-turn-helix 4 58 7.1E-15 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 ALX04_RS06970 46a797bb0fe1857f08c22af298603838 188 SMART SM00530 3 58 1.4E-15 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 ALX04_RS06970 46a797bb0fe1857f08c22af298603838 188 Gene3D G3DSA:1.10.3100.10 2 188 1.7E-20 T 28-03-2018 IPR027910 YdiL-like domain ALX04_RS06970 46a797bb0fe1857f08c22af298603838 188 SUPERFAMILY SSF47413 2 60 8.7E-17 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 ALX04_RS08770 ecf5ffe9c86af3e5ce0bb1dde27bdeac 109 Gene3D G3DSA:1.10.10.10 1 99 2.6E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS08770 ecf5ffe9c86af3e5ce0bb1dde27bdeac 109 Pfam PF01022 Bacterial regulatory protein, arsR family 23 68 5.8E-10 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 ALX04_RS08770 ecf5ffe9c86af3e5ce0bb1dde27bdeac 109 SMART SM00418 16 100 9.6E-15 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 ALX04_RS08770 ecf5ffe9c86af3e5ce0bb1dde27bdeac 109 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 52 67 4.8E-9 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 ALX04_RS08770 ecf5ffe9c86af3e5ce0bb1dde27bdeac 109 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 18 33 4.8E-9 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 ALX04_RS08770 ecf5ffe9c86af3e5ce0bb1dde27bdeac 109 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 67 82 4.8E-9 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 ALX04_RS08770 ecf5ffe9c86af3e5ce0bb1dde27bdeac 109 SUPERFAMILY SSF46785 11 96 7.8E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS14900 85e6d4a360fa018cc93085d01979fd4a 605 Pfam PF13522 Glutamine amidotransferase domain 60 182 2.2E-19 T 28-03-2018 ALX04_RS14900 85e6d4a360fa018cc93085d01979fd4a 605 Gene3D G3DSA:3.60.20.10 2 241 7.1E-60 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal ALX04_RS14900 85e6d4a360fa018cc93085d01979fd4a 605 Gene3D G3DSA:3.40.50.10490 242 456 3.6E-48 T 28-03-2018 ALX04_RS14900 85e6d4a360fa018cc93085d01979fd4a 605 Hamap MF_00164 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] [glmS]. 1 605 37.616 T 28-03-2018 IPR005855 Glucosamine-fructose-6-phosphate aminotransferase, isomerising GO:0004360|GO:1901137 KEGG: 00250+2.6.1.16|KEGG: 00520+2.6.1.16|MetaCyc: PWY-6749|Reactome: R-HSA-446210 ALX04_RS14900 85e6d4a360fa018cc93085d01979fd4a 605 SUPERFAMILY SSF53697 247 605 1.16E-87 T 28-03-2018 ALX04_RS14900 85e6d4a360fa018cc93085d01979fd4a 605 Pfam PF01380 SIS domain 290 415 6.3E-26 T 28-03-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 ALX04_RS14900 85e6d4a360fa018cc93085d01979fd4a 605 Pfam PF01380 SIS domain 465 586 1.3E-19 T 28-03-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 ALX04_RS14900 85e6d4a360fa018cc93085d01979fd4a 605 Gene3D G3DSA:3.40.50.10490 457 603 5.4E-40 T 28-03-2018 ALX04_RS14900 85e6d4a360fa018cc93085d01979fd4a 605 SUPERFAMILY SSF56235 2 238 7.03E-62 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal ALX04_RS14900 85e6d4a360fa018cc93085d01979fd4a 605 TIGRFAM TIGR01135 glmS: glutamine-fructose-6-phosphate transaminase (isomerizing) 2 605 3.1E-205 T 28-03-2018 IPR005855 Glucosamine-fructose-6-phosphate aminotransferase, isomerising GO:0004360|GO:1901137 KEGG: 00250+2.6.1.16|KEGG: 00520+2.6.1.16|MetaCyc: PWY-6749|Reactome: R-HSA-446210 ALX04_RS00505 fc24fd6391390729e1155a8aa2aa9db2 129 PIRSF PIRSF002131 1 129 1.5E-52 T 28-03-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 ALX04_RS00505 fc24fd6391390729e1155a8aa2aa9db2 129 Pfam PF00411 Ribosomal protein S11 19 128 3.5E-51 T 28-03-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 ALX04_RS00505 fc24fd6391390729e1155a8aa2aa9db2 129 SUPERFAMILY SSF53137 14 129 2.22E-48 T 28-03-2018 ALX04_RS00505 fc24fd6391390729e1155a8aa2aa9db2 129 TIGRFAM TIGR03632 uS11_bact: ribosomal protein uS11 10 126 7.4E-58 T 28-03-2018 IPR019981 Ribosomal protein S11, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 ALX04_RS00505 fc24fd6391390729e1155a8aa2aa9db2 129 Gene3D G3DSA:3.30.420.80 3 129 1.6E-43 T 28-03-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 ALX04_RS00505 fc24fd6391390729e1155a8aa2aa9db2 129 Hamap MF_01310 30S ribosomal protein S11 [rpsK]. 4 129 33.408 T 28-03-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 ALX04_RS00505 fc24fd6391390729e1155a8aa2aa9db2 129 ProSitePatterns PS00054 Ribosomal protein S11 signature. 97 119 - T 28-03-2018 IPR018102 Ribosomal S11, conserved site ALX04_RS14580 5853e2f22050f9194f67bfd5b128c8d9 251 Gene3D G3DSA:3.40.50.300 1 249 1.2E-59 T 28-03-2018 ALX04_RS14580 5853e2f22050f9194f67bfd5b128c8d9 251 TIGRFAM TIGR00972 3a0107s01c2: phosphate ABC transporter, ATP-binding protein 5 251 4.9E-122 T 28-03-2018 IPR005670 Phosphate transport system permease protein 1 GO:0005315|GO:0016020|GO:0035435 ALX04_RS14580 5853e2f22050f9194f67bfd5b128c8d9 251 Pfam PF00005 ABC transporter 20 176 3.8E-31 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 ALX04_RS14580 5853e2f22050f9194f67bfd5b128c8d9 251 SUPERFAMILY SSF52540 4 237 2.89E-59 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase ALX04_RS14580 5853e2f22050f9194f67bfd5b128c8d9 251 ProSitePatterns PS00211 ABC transporters family signature. 148 162 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 ALX04_RS14580 5853e2f22050f9194f67bfd5b128c8d9 251 SMART SM00382 29 223 3.0E-13 T 28-03-2018 IPR003593 AAA+ ATPase domain ALX04_RS01665 c831be5c8ad54308aa7ce5a19cdaaa80 278 Gene3D G3DSA:3.40.1190.20 2 277 1.7E-49 T 28-03-2018 IPR029056 Ribokinase-like ALX04_RS01665 c831be5c8ad54308aa7ce5a19cdaaa80 278 Pfam PF01256 Carbohydrate kinase 29 266 7.3E-62 T 28-03-2018 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 ALX04_RS01665 c831be5c8ad54308aa7ce5a19cdaaa80 278 ProSitePatterns PS01050 YjeF C-terminal domain signature 2. 211 221 - T 28-03-2018 IPR017953 Carbohydrate kinase, predicted, conserved site ALX04_RS01665 c831be5c8ad54308aa7ce5a19cdaaa80 278 SUPERFAMILY SSF53613 3 271 2.52E-64 T 28-03-2018 IPR029056 Ribokinase-like ALX04_RS01665 c831be5c8ad54308aa7ce5a19cdaaa80 278 Hamap MF_01965 ADP-dependent (S)-NAD(P)H-hydrate dehydratase [nnrD]. 5 274 23.198 T 28-03-2018 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 ALX04_RS01665 c831be5c8ad54308aa7ce5a19cdaaa80 278 TIGRFAM TIGR00196 yjeF_cterm: YjeF family C-terminal domain 5 270 2.7E-58 T 28-03-2018 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 ALX04_RS01665 c831be5c8ad54308aa7ce5a19cdaaa80 278 ProSitePatterns PS01049 YjeF C-terminal domain signature 1. 95 105 - T 28-03-2018 IPR017953 Carbohydrate kinase, predicted, conserved site ALX04_RS01750 71d8f6565b51c3767315c3f9c9dc3148 130 Pfam PF09278 MerR, DNA binding 65 108 8.9E-7 T 28-03-2018 IPR015358 Transcription regulator MerR, DNA binding ALX04_RS01750 71d8f6565b51c3767315c3f9c9dc3148 130 SMART SM00422 8 77 1.1E-13 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 ALX04_RS01750 71d8f6565b51c3767315c3f9c9dc3148 130 SUPERFAMILY SSF46955 8 120 1.06E-25 T 28-03-2018 IPR009061 Putative DNA-binding domain ALX04_RS01750 71d8f6565b51c3767315c3f9c9dc3148 130 Pfam PF00376 MerR family regulatory protein 9 46 1.8E-11 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 ALX04_RS01750 71d8f6565b51c3767315c3f9c9dc3148 130 Gene3D G3DSA:1.10.1660.10 66 130 3.7E-9 T 28-03-2018 ALX04_RS01750 71d8f6565b51c3767315c3f9c9dc3148 130 Gene3D G3DSA:1.10.1660.10 4 65 1.4E-16 T 28-03-2018 ALX04_RS11005 a1b5783a479e6fe75ec3b1c220e85e85 487 Pfam PF01087 Galactose-1-phosphate uridyl transferase, N-terminal domain 17 224 1.5E-35 T 28-03-2018 IPR005849 Galactose-1-phosphate uridyl transferase, N-terminal GO:0006012|GO:0008108 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527|Reactome: R-HSA-70370 ALX04_RS11005 a1b5783a479e6fe75ec3b1c220e85e85 487 Hamap MF_00571 Galactose-1-phosphate uridylyltransferase [galT]. 1 487 278.173 T 28-03-2018 IPR000766 Galactose-1-phosphate uridyl transferase, class II GO:0005737|GO:0006012|GO:0008108 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527 ALX04_RS11005 a1b5783a479e6fe75ec3b1c220e85e85 487 PIRSF PIRSF006005 1 487 1.8E-227 T 28-03-2018 IPR000766 Galactose-1-phosphate uridyl transferase, class II GO:0005737|GO:0006012|GO:0008108 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527 ALX04_RS11005 a1b5783a479e6fe75ec3b1c220e85e85 487 TIGRFAM TIGR01239 galT_2: galactose-1-phosphate uridylyltransferase 4 483 2.0E-216 T 28-03-2018 IPR000766 Galactose-1-phosphate uridyl transferase, class II GO:0005737|GO:0006012|GO:0008108 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527 ALX04_RS11005 a1b5783a479e6fe75ec3b1c220e85e85 487 ProSitePatterns PS01163 Galactose-1-phosphate uridyl transferase family 2 signature. 252 269 - T 28-03-2018 IPR023425 Galactose-1-phosphate uridyl transferase, class II, conserved site GO:0008108 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527 ALX04_RS11005 a1b5783a479e6fe75ec3b1c220e85e85 487 Pfam PF02744 Galactose-1-phosphate uridyl transferase, C-terminal domain 239 432 5.2E-29 T 28-03-2018 IPR005850 Galactose-1-phosphate uridyl transferase, C-terminal GO:0006012|GO:0008108 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527|Reactome: R-HSA-70370 ALX04_RS10320 b71b0dfe919da55dae1d857319d3a99e 189 TIGRFAM TIGR00063 folE: GTP cyclohydrolase I 10 188 3.3E-61 T 28-03-2018 IPR001474 GTP cyclohydrolase I GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 ALX04_RS10320 b71b0dfe919da55dae1d857319d3a99e 189 SUPERFAMILY SSF55620 4 187 2.82E-65 T 28-03-2018 ALX04_RS10320 b71b0dfe919da55dae1d857319d3a99e 189 Gene3D G3DSA:1.10.286.10 8 49 1.7E-18 T 28-03-2018 ALX04_RS10320 b71b0dfe919da55dae1d857319d3a99e 189 Hamap MF_00223 GTP cyclohydrolase 1 [folE]. 6 188 35.427 T 28-03-2018 IPR001474 GTP cyclohydrolase I GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 ALX04_RS10320 b71b0dfe919da55dae1d857319d3a99e 189 ProSitePatterns PS00859 GTP cyclohydrolase I signature 1. 66 82 - T 28-03-2018 IPR018234 GTP cyclohydrolase I, conserved site GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 ALX04_RS10320 b71b0dfe919da55dae1d857319d3a99e 189 Pfam PF01227 GTP cyclohydrolase I 10 187 4.7E-69 T 28-03-2018 IPR020602 GTP cyclohydrolase I domain KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 ALX04_RS10320 b71b0dfe919da55dae1d857319d3a99e 189 Gene3D G3DSA:3.30.1130.10 56 189 2.5E-49 T 28-03-2018 ALX04_RS09215 f95525d85fb49f33f4d20f77718f57e8 148 Pfam PF00358 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 11 120 3.9E-14 T 28-03-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 ALX04_RS09215 f95525d85fb49f33f4d20f77718f57e8 148 Gene3D G3DSA:2.70.70.10 5 147 9.7E-21 T 28-03-2018 ALX04_RS09215 f95525d85fb49f33f4d20f77718f57e8 148 SUPERFAMILY SSF51261 5 146 4.71E-21 T 28-03-2018 IPR011055 Duplicated hybrid motif ALX04_RS15410 d3505aa953e3e0d03a98929aaf97e441 668 Pfam PF06458 MucBP domain 277 339 1.4E-14 T 28-03-2018 IPR009459 MucBP domain ALX04_RS15410 d3505aa953e3e0d03a98929aaf97e441 668 Pfam PF06458 MucBP domain 346 408 2.0E-16 T 28-03-2018 IPR009459 MucBP domain ALX04_RS15410 d3505aa953e3e0d03a98929aaf97e441 668 Pfam PF06458 MucBP domain 488 550 4.8E-11 T 28-03-2018 IPR009459 MucBP domain ALX04_RS15410 d3505aa953e3e0d03a98929aaf97e441 668 Pfam PF06458 MucBP domain 2 59 2.0E-7 T 28-03-2018 IPR009459 MucBP domain ALX04_RS15410 d3505aa953e3e0d03a98929aaf97e441 668 Pfam PF06458 MucBP domain 207 270 1.1E-15 T 28-03-2018 IPR009459 MucBP domain ALX04_RS15410 d3505aa953e3e0d03a98929aaf97e441 668 Pfam PF06458 MucBP domain 66 129 5.4E-15 T 28-03-2018 IPR009459 MucBP domain ALX04_RS15410 d3505aa953e3e0d03a98929aaf97e441 668 Pfam PF06458 MucBP domain 414 476 5.2E-16 T 28-03-2018 IPR009459 MucBP domain ALX04_RS15410 d3505aa953e3e0d03a98929aaf97e441 668 Pfam PF06458 MucBP domain 137 199 4.6E-11 T 28-03-2018 IPR009459 MucBP domain ALX04_RS15410 d3505aa953e3e0d03a98929aaf97e441 668 Gene3D G3DSA:3.10.20.320 485 559 9.2E-15 T 28-03-2018 ALX04_RS15410 d3505aa953e3e0d03a98929aaf97e441 668 Gene3D G3DSA:3.10.20.320 204 273 2.0E-20 T 28-03-2018 ALX04_RS15410 d3505aa953e3e0d03a98929aaf97e441 668 Gene3D G3DSA:3.10.20.320 413 484 1.1E-17 T 28-03-2018 ALX04_RS15410 d3505aa953e3e0d03a98929aaf97e441 668 Gene3D G3DSA:3.10.20.320 1 62 4.7E-9 T 28-03-2018 ALX04_RS15410 d3505aa953e3e0d03a98929aaf97e441 668 Gene3D G3DSA:3.10.20.320 63 133 2.5E-18 T 28-03-2018 ALX04_RS15410 d3505aa953e3e0d03a98929aaf97e441 668 Gene3D G3DSA:3.10.20.320 274 343 7.4E-18 T 28-03-2018 ALX04_RS15410 d3505aa953e3e0d03a98929aaf97e441 668 Gene3D G3DSA:3.10.20.320 134 203 3.4E-16 T 28-03-2018 ALX04_RS15410 d3505aa953e3e0d03a98929aaf97e441 668 Gene3D G3DSA:3.10.20.320 344 412 8.4E-19 T 28-03-2018 ALX04_RS15410 d3505aa953e3e0d03a98929aaf97e441 668 TIGRFAM TIGR01167 LPXTG_anchor: LPXTG cell wall anchor domain 635 666 9.7E-4 T 28-03-2018 ALX04_RS08015 6c129446d7f8de63906581d7550dc797 138 Pfam PF04138 GtrA-like protein 18 133 7.1E-23 T 28-03-2018 IPR007267 GtrA-like protein GO:0000271|GO:0006810|GO:0016021 ALX04_RS13210 0d66cb109862564972c08f3de1d83876 1227 Pfam PF06458 MucBP domain 511 574 5.4E-10 T 28-03-2018 IPR009459 MucBP domain ALX04_RS13210 0d66cb109862564972c08f3de1d83876 1227 TIGRFAM TIGR01167 LPXTG_anchor: LPXTG cell wall anchor domain 1192 1224 4.6E-4 T 28-03-2018 ALX04_RS13210 0d66cb109862564972c08f3de1d83876 1227 Gene3D G3DSA:3.10.20.320 432 509 0.0011 T 28-03-2018 ALX04_RS13210 0d66cb109862564972c08f3de1d83876 1227 Gene3D G3DSA:3.10.20.320 510 599 3.4E-8 T 28-03-2018 ALX04_RS03345 cc12a158fe3a455ca2f61ad713af1c71 241 Pfam PF07261 Replication initiation and membrane attachment 132 204 4.8E-25 T 28-03-2018 IPR006343 DnaD domain ALX04_RS03345 cc12a158fe3a455ca2f61ad713af1c71 241 SUPERFAMILY SSF158499 132 197 3.14E-19 T 28-03-2018 IPR006343 DnaD domain ALX04_RS03345 cc12a158fe3a455ca2f61ad713af1c71 241 TIGRFAM TIGR01446 DnaD_dom: DnaD domain protein 133 203 3.0E-22 T 28-03-2018 IPR006343 DnaD domain ALX04_RS03345 cc12a158fe3a455ca2f61ad713af1c71 241 Gene3D G3DSA:1.10.10.630 130 203 4.1E-24 T 28-03-2018 IPR034829 DnaD-like domain ALX04_RS09375 f97a5348c5ce0e586f39e4317790ad5c 141 Pfam PF10604 Polyketide cyclase / dehydrase and lipid transport 6 135 3.2E-8 T 28-03-2018 IPR019587 Polyketide cyclase/dehydrase ALX04_RS09375 f97a5348c5ce0e586f39e4317790ad5c 141 Gene3D G3DSA:3.30.530.20 2 141 7.4E-13 T 28-03-2018 IPR023393 START-like domain ALX04_RS09375 f97a5348c5ce0e586f39e4317790ad5c 141 SUPERFAMILY SSF55961 5 136 2.31E-11 T 28-03-2018 ALX04_RS07280 780c7d27d676b363ba7476009c04f188 108 SUPERFAMILY SSF141734 5 104 9.55E-46 T 28-03-2018 ALX04_RS07280 780c7d27d676b363ba7476009c04f188 108 Hamap MF_01021 Phosphoribosyl-AMP cyclohydrolase [hisI]. 1 103 29.254 T 28-03-2018 IPR026660 Phosphoribosyl-AMP cyclohydrolase GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19 ALX04_RS07280 780c7d27d676b363ba7476009c04f188 108 Pfam PF01502 Phosphoribosyl-AMP cyclohydrolase 26 99 3.4E-35 T 28-03-2018 IPR002496 Phosphoribosyl-AMP cyclohydrolase domain GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19 ALX04_RS07280 780c7d27d676b363ba7476009c04f188 108 ProDom PD002610 PHOSPHORIBOSYL-AMP BIOSYNTHESIS CYCLOHYDROLASE HYDROLASE HISTIDINE AMINO-ACID PRA-CH PHOSPHORIBOSYL-ATP BIFUNCTIONAL INCLUDES: 49 98 5.0E-24 T 28-03-2018 IPR002496 Phosphoribosyl-AMP cyclohydrolase domain GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19 ALX04_RS09240 bf1f8ff2056cbc44aaecdac2bfc0c67f 147 SUPERFAMILY SSF46955 3 119 3.0E-31 T 28-03-2018 IPR009061 Putative DNA-binding domain ALX04_RS09240 bf1f8ff2056cbc44aaecdac2bfc0c67f 147 Pfam PF13411 MerR HTH family regulatory protein 3 70 2.4E-18 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 ALX04_RS09240 bf1f8ff2056cbc44aaecdac2bfc0c67f 147 SMART SM00422 3 72 1.4E-21 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 ALX04_RS09240 bf1f8ff2056cbc44aaecdac2bfc0c67f 147 Gene3D G3DSA:1.10.1660.10 58 140 1.1E-11 T 28-03-2018 ALX04_RS09240 bf1f8ff2056cbc44aaecdac2bfc0c67f 147 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 4 15 8.9E-5 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 ALX04_RS09240 bf1f8ff2056cbc44aaecdac2bfc0c67f 147 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 15 28 8.9E-5 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 ALX04_RS09240 bf1f8ff2056cbc44aaecdac2bfc0c67f 147 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 39 59 8.9E-5 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 ALX04_RS09240 bf1f8ff2056cbc44aaecdac2bfc0c67f 147 Gene3D G3DSA:1.10.1660.10 1 57 4.7E-20 T 28-03-2018 ALX04_RS09600 127897745d1eaf457d0febb8f7cf14e4 70 Gene3D G3DSA:1.10.10.10 1 58 9.3E-7 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS09600 127897745d1eaf457d0febb8f7cf14e4 70 Pfam PF13518 Helix-turn-helix domain 7 55 8.7E-6 T 28-03-2018 ALX04_RS09600 127897745d1eaf457d0febb8f7cf14e4 70 SUPERFAMILY SSF46689 2 52 1.36E-5 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 ALX04_RS11110 e180f5139531642ce5c33e6427aa6e23 301 Gene3D G3DSA:3.40.190.10 91 179 7.4E-18 T 28-03-2018 ALX04_RS11110 e180f5139531642ce5c33e6427aa6e23 301 SUPERFAMILY SSF53850 88 296 1.19E-36 T 28-03-2018 ALX04_RS11110 e180f5139531642ce5c33e6427aa6e23 301 Pfam PF03466 LysR substrate binding domain 89 292 2.4E-36 T 28-03-2018 IPR005119 LysR, substrate-binding ALX04_RS11110 e180f5139531642ce5c33e6427aa6e23 301 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 62 1.1E-18 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 ALX04_RS11110 e180f5139531642ce5c33e6427aa6e23 301 Gene3D G3DSA:3.40.190.10 180 264 2.0E-17 T 28-03-2018 ALX04_RS11110 e180f5139531642ce5c33e6427aa6e23 301 Gene3D G3DSA:1.10.10.10 1 90 3.9E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS11110 e180f5139531642ce5c33e6427aa6e23 301 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 1.6E-6 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 ALX04_RS11110 e180f5139531642ce5c33e6427aa6e23 301 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 1.6E-6 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 ALX04_RS11110 e180f5139531642ce5c33e6427aa6e23 301 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 1.6E-6 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 ALX04_RS11110 e180f5139531642ce5c33e6427aa6e23 301 SUPERFAMILY SSF46785 1 87 1.86E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS02610 7f515c658d3357e9dc00e1222061ed5a 137 SMART SM00450 39 134 9.5E-18 T 28-03-2018 IPR001763 Rhodanese-like domain ALX04_RS02610 7f515c658d3357e9dc00e1222061ed5a 137 SUPERFAMILY SSF52821 27 130 2.36E-26 T 28-03-2018 IPR001763 Rhodanese-like domain ALX04_RS02610 7f515c658d3357e9dc00e1222061ed5a 137 Gene3D G3DSA:3.40.250.10 26 136 1.1E-21 T 28-03-2018 IPR001763 Rhodanese-like domain ALX04_RS02610 7f515c658d3357e9dc00e1222061ed5a 137 Pfam PF00581 Rhodanese-like domain 49 129 8.5E-13 T 28-03-2018 IPR001763 Rhodanese-like domain ALX04_RS11285 406e78e821217a2e8c99e14520a462e5 796 SUPERFAMILY SSF52518 10 373 1.13E-73 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold ALX04_RS11285 406e78e821217a2e8c99e14520a462e5 796 Gene3D G3DSA:3.40.50.970 384 609 8.1E-26 T 28-03-2018 ALX04_RS11285 406e78e821217a2e8c99e14520a462e5 796 Gene3D G3DSA:3.40.50.970 2 383 2.5E-80 T 28-03-2018 ALX04_RS11285 406e78e821217a2e8c99e14520a462e5 796 Hamap MF_01403 Probable phosphoketolase. 10 794 39.819 T 28-03-2018 IPR023962 Probable phosphoketolase ALX04_RS11285 406e78e821217a2e8c99e14520a462e5 796 SUPERFAMILY SSF52518 382 600 4.24E-30 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold ALX04_RS11285 406e78e821217a2e8c99e14520a462e5 796 ProSitePatterns PS60003 Phosphoketolase signature 2. 162 180 - T 28-03-2018 IPR019789 Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase, thiamine diphosphate binding site GO:0005975|GO:0016832 ALX04_RS11285 406e78e821217a2e8c99e14520a462e5 796 Pfam PF09364 XFP N-terminal domain 14 389 6.1E-185 T 28-03-2018 IPR018970 Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase, N-terminal ALX04_RS11285 406e78e821217a2e8c99e14520a462e5 796 Pfam PF09363 XFP C-terminal domain 594 792 6.2E-81 T 28-03-2018 IPR018969 Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase, C-terminal GO:0005975|GO:0016832 ALX04_RS11285 406e78e821217a2e8c99e14520a462e5 796 ProSitePatterns PS60002 Phosphoketolase signature 1. 149 155 - T 28-03-2018 IPR019790 Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase, conserved site GO:0005975|GO:0016832 ALX04_RS11285 406e78e821217a2e8c99e14520a462e5 796 Gene3D G3DSA:3.40.50.920 614 794 4.7E-67 T 28-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 ALX04_RS11285 406e78e821217a2e8c99e14520a462e5 796 Pfam PF03894 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase 404 583 1.2E-72 T 28-03-2018 IPR005593 Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase GO:0005975|GO:0016832 ALX04_RS11285 406e78e821217a2e8c99e14520a462e5 796 PIRSF PIRSF017245 1 794 0.0 T 28-03-2018 IPR005593 Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase GO:0005975|GO:0016832 ALX04_RS09495 10fcf807c5b1ecfb55f58840ea5b82c5 202 Pfam PF13731 WxL domain surface cell wall-binding 52 199 6.1E-25 T 28-03-2018 IPR027994 WxL domain ALX04_RS14215 3eaa12aaebd2d7ba797e7809891a73bf 98 Gene3D G3DSA:3.40.630.30 1 98 5.6E-18 T 28-03-2018 ALX04_RS14215 3eaa12aaebd2d7ba797e7809891a73bf 98 Pfam PF14542 GCN5-related N-acetyl-transferase 9 89 2.4E-22 T 28-03-2018 IPR031165 Yjdj-type Gcn5-related N-acetyltransferase ALX04_RS14215 3eaa12aaebd2d7ba797e7809891a73bf 98 SUPERFAMILY SSF55729 2 90 4.61E-25 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase ALX04_RS11365 da6dec44645134582a05aeb2711c78c9 145 SUPERFAMILY SSF52833 1 122 1.34E-32 T 28-03-2018 IPR012336 Thioredoxin-like fold ALX04_RS11365 da6dec44645134582a05aeb2711c78c9 145 Pfam PF03960 ArsC family 56 113 2.1E-15 T 28-03-2018 IPR006660 Arsenate reductase-like ALX04_RS11365 da6dec44645134582a05aeb2711c78c9 145 TIGRFAM TIGR01617 arsC_related: transcriptional regulator, Spx/MgsR family 2 114 3.6E-28 T 28-03-2018 IPR006504 Transcriptional regulator Spx/MgsR ALX04_RS11365 da6dec44645134582a05aeb2711c78c9 145 Gene3D G3DSA:3.40.30.10 1 129 1.4E-30 T 28-03-2018 ALX04_RS14600 a72bc2f878c3c40d507f2e32039a1bb3 315 Gene3D G3DSA:3.40.1390.20 4 134 5.1E-41 T 28-03-2018 IPR028979 HPr(Ser) kinase/phosphorylase, N-terminal domain-like ALX04_RS14600 a72bc2f878c3c40d507f2e32039a1bb3 315 SUPERFAMILY SSF53795 134 301 1.37E-41 T 28-03-2018 ALX04_RS14600 a72bc2f878c3c40d507f2e32039a1bb3 315 SUPERFAMILY SSF75138 4 133 1.96E-37 T 28-03-2018 IPR028979 HPr(Ser) kinase/phosphorylase, N-terminal domain-like ALX04_RS14600 a72bc2f878c3c40d507f2e32039a1bb3 315 Pfam PF02603 HPr Serine kinase N terminus 5 129 2.6E-39 T 28-03-2018 IPR011126 HPr(Ser) kinase/phosphorylase, N-terminal GO:0000155|GO:0000160|GO:0004672|GO:0005524|GO:0006109 ALX04_RS14600 a72bc2f878c3c40d507f2e32039a1bb3 315 Gene3D G3DSA:3.40.50.300 137 309 9.5E-46 T 28-03-2018 ALX04_RS14600 a72bc2f878c3c40d507f2e32039a1bb3 315 TIGRFAM TIGR00679 hpr-ser: HPr(Ser) kinase/phosphatase 5 304 5.0E-113 T 28-03-2018 IPR003755 HPr(Ser) kinase/phosphorylase GO:0000155|GO:0000160|GO:0005524|GO:0006109 ALX04_RS14600 a72bc2f878c3c40d507f2e32039a1bb3 315 Hamap MF_01249 HPr kinase/phosphorylase [hprK]. 4 308 41.172 T 28-03-2018 IPR003755 HPr(Ser) kinase/phosphorylase GO:0000155|GO:0000160|GO:0005524|GO:0006109 ALX04_RS14600 a72bc2f878c3c40d507f2e32039a1bb3 315 Pfam PF07475 HPr Serine kinase C-terminal domain 132 300 3.1E-76 T 28-03-2018 IPR011104 HPr kinase/phosphorylase, C-terminal GO:0000155|GO:0000160|GO:0004672|GO:0005524|GO:0006109 ALX04_RS10760 522f1258b6cf6849f9ce178a5cd3f519 370 SUPERFAMILY SSF54001 259 362 1.32E-30 T 28-03-2018 ALX04_RS10760 522f1258b6cf6849f9ce178a5cd3f519 370 Pfam PF01476 LysM domain 47 89 1.5E-12 T 28-03-2018 IPR018392 LysM domain ALX04_RS10760 522f1258b6cf6849f9ce178a5cd3f519 370 SUPERFAMILY SSF54106 47 89 1.07E-8 T 28-03-2018 IPR018392 LysM domain ALX04_RS10760 522f1258b6cf6849f9ce178a5cd3f519 370 Gene3D G3DSA:3.90.1720.10 254 367 3.5E-26 T 28-03-2018 ALX04_RS10760 522f1258b6cf6849f9ce178a5cd3f519 370 Gene3D G3DSA:3.10.350.10 44 90 5.2E-15 T 28-03-2018 ALX04_RS10760 522f1258b6cf6849f9ce178a5cd3f519 370 SMART SM00257 45 89 1.2E-11 T 28-03-2018 IPR018392 LysM domain ALX04_RS10760 522f1258b6cf6849f9ce178a5cd3f519 370 Pfam PF00877 NlpC/P60 family 276 364 2.6E-20 T 28-03-2018 IPR000064 Endopeptidase, NLPC/P60 domain ALX04_RS10600 e15b721745aef188f55eb27a614aa68d 477 Gene3D G3DSA:1.20.1250.20 17 201 3.6E-25 T 28-03-2018 ALX04_RS10600 e15b721745aef188f55eb27a614aa68d 477 Pfam PF07690 Major Facilitator Superfamily 29 419 1.4E-34 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 ALX04_RS10600 e15b721745aef188f55eb27a614aa68d 477 PRINTS PR01036 Tetracycline resistance protein TetB signature 118 138 1.8E-10 T 28-03-2018 ALX04_RS10600 e15b721745aef188f55eb27a614aa68d 477 PRINTS PR01036 Tetracycline resistance protein TetB signature 148 172 1.8E-10 T 28-03-2018 ALX04_RS10600 e15b721745aef188f55eb27a614aa68d 477 PRINTS PR01036 Tetracycline resistance protein TetB signature 27 51 1.8E-10 T 28-03-2018 ALX04_RS10600 e15b721745aef188f55eb27a614aa68d 477 PRINTS PR01036 Tetracycline resistance protein TetB signature 312 336 1.8E-10 T 28-03-2018 ALX04_RS10600 e15b721745aef188f55eb27a614aa68d 477 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 22 435 1.2E-82 T 28-03-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 ALX04_RS10600 e15b721745aef188f55eb27a614aa68d 477 Gene3D G3DSA:1.20.1250.20 262 477 6.5E-19 T 28-03-2018 ALX04_RS10600 e15b721745aef188f55eb27a614aa68d 477 SUPERFAMILY SSF103473 16 207 1.74E-51 T 28-03-2018 IPR020846 Major facilitator superfamily domain ALX04_RS10600 e15b721745aef188f55eb27a614aa68d 477 SUPERFAMILY SSF103473 258 475 1.74E-51 T 28-03-2018 IPR020846 Major facilitator superfamily domain ALX04_RS00800 3c8315718a98f90e0606c679983edbce 331 PIRSF PIRSF000267 1 331 2.0E-98 T 28-03-2018 IPR003317 Cytochrome ubiquinol oxidase subunit 2 GO:0016020|GO:0055114 ALX04_RS00800 3c8315718a98f90e0606c679983edbce 331 TIGRFAM TIGR00203 cydB: cytochrome d ubiquinol oxidase, subunit II 2 226 1.2E-74 T 28-03-2018 IPR003317 Cytochrome ubiquinol oxidase subunit 2 GO:0016020|GO:0055114 ALX04_RS00800 3c8315718a98f90e0606c679983edbce 331 Pfam PF02322 Cytochrome bd terminal oxidase subunit II 4 325 5.9E-96 T 28-03-2018 IPR003317 Cytochrome ubiquinol oxidase subunit 2 GO:0016020|GO:0055114 ALX04_RS12140 9f35da2a6d298f4638c53f9aa74aae8e 168 Pfam PF04397 LytTr DNA-binding domain 72 165 9.2E-16 T 28-03-2018 IPR007492 LytTR DNA-binding domain GO:0003677 ALX04_RS12140 9f35da2a6d298f4638c53f9aa74aae8e 168 SMART SM00850 70 167 6.4E-18 T 28-03-2018 IPR007492 LytTR DNA-binding domain GO:0003677 ALX04_RS12140 9f35da2a6d298f4638c53f9aa74aae8e 168 Gene3D G3DSA:2.40.50.40 60 129 1.2E-8 T 28-03-2018 ALX04_RS14200 8b4a4dad67fb3ed54cab1c6530b327ac 230 Pfam PF00413 Matrixin 84 229 3.4E-13 T 28-03-2018 IPR001818 Peptidase M10, metallopeptidase GO:0004222|GO:0006508|GO:0008270|GO:0031012 ALX04_RS14200 8b4a4dad67fb3ed54cab1c6530b327ac 230 Gene3D G3DSA:3.40.390.10 36 230 9.8E-25 T 28-03-2018 IPR024079 Metallopeptidase, catalytic domain GO:0008237 ALX04_RS14200 8b4a4dad67fb3ed54cab1c6530b327ac 230 SMART SM00235 77 228 2.9E-5 T 28-03-2018 IPR006026 Peptidase, metallopeptidase GO:0006508|GO:0008237|GO:0008270 ALX04_RS14200 8b4a4dad67fb3ed54cab1c6530b327ac 230 SUPERFAMILY SSF55486 46 229 2.73E-36 T 28-03-2018 ALX04_RS13300 d3f142f3aa509c2fe1c63acd44d321d4 154 SUPERFAMILY SSF52038 51 126 2.3E-5 T 28-03-2018 IPR000468 Barstar (barnase inhibitor) ALX04_RS13300 d3f142f3aa509c2fe1c63acd44d321d4 154 Gene3D G3DSA:3.30.370.10 50 134 0.0012 T 28-03-2018 IPR000468 Barstar (barnase inhibitor) ALX04_RS01590 5f334ee808d70828c1f380a0e3e18a36 498 Pfam PF00534 Glycosyl transferases group 1 322 477 4.0E-28 T 28-03-2018 IPR001296 Glycosyl transferase, family 1 ALX04_RS01590 5f334ee808d70828c1f380a0e3e18a36 498 Gene3D G3DSA:3.40.50.2000 312 482 4.7E-36 T 28-03-2018 ALX04_RS01590 5f334ee808d70828c1f380a0e3e18a36 498 SUPERFAMILY SSF53756 153 496 1.2E-49 T 28-03-2018 ALX04_RS08210 74481d76ba3f1fa339f1b7ee26aa7774 190 Pfam PF03807 NADP oxidoreductase coenzyme F420-dependent 32 73 5.1E-5 T 28-03-2018 IPR028939 Pyrroline-5-carboxylate reductase, catalytic, N-terminal ALX04_RS08210 74481d76ba3f1fa339f1b7ee26aa7774 190 Gene3D G3DSA:3.40.50.720 1 169 2.1E-29 T 28-03-2018 ALX04_RS08210 74481d76ba3f1fa339f1b7ee26aa7774 190 SUPERFAMILY SSF51735 1 176 7.41E-30 T 28-03-2018 IPR016040 NAD(P)-binding domain ALX04_RS13190 02bc2f2ace1ffe3f15eed6a06e8c8dbf 443 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 250 266 4.5E-26 T 28-03-2018 ALX04_RS13190 02bc2f2ace1ffe3f15eed6a06e8c8dbf 443 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 278 300 4.5E-26 T 28-03-2018 ALX04_RS13190 02bc2f2ace1ffe3f15eed6a06e8c8dbf 443 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 7 26 4.5E-26 T 28-03-2018 ALX04_RS13190 02bc2f2ace1ffe3f15eed6a06e8c8dbf 443 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 167 185 4.5E-26 T 28-03-2018 ALX04_RS13190 02bc2f2ace1ffe3f15eed6a06e8c8dbf 443 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 130 148 4.5E-26 T 28-03-2018 ALX04_RS13190 02bc2f2ace1ffe3f15eed6a06e8c8dbf 443 Gene3D G3DSA:3.30.390.30 328 443 1.0E-22 T 28-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 ALX04_RS13190 02bc2f2ace1ffe3f15eed6a06e8c8dbf 443 SUPERFAMILY SSF55424 331 442 2.41E-24 T 28-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 ALX04_RS13190 02bc2f2ace1ffe3f15eed6a06e8c8dbf 443 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 334 439 2.5E-14 T 28-03-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 ALX04_RS13190 02bc2f2ace1ffe3f15eed6a06e8c8dbf 443 Gene3D G3DSA:1.10.287.990 38 102 1.3E-14 T 28-03-2018 ALX04_RS13190 02bc2f2ace1ffe3f15eed6a06e8c8dbf 443 PIRSF PIRSF000350 1 442 6.3E-65 T 28-03-2018 ALX04_RS13190 02bc2f2ace1ffe3f15eed6a06e8c8dbf 443 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 5 314 3.5E-56 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ALX04_RS13190 02bc2f2ace1ffe3f15eed6a06e8c8dbf 443 Gene3D G3DSA:3.40.50.720 160 327 4.3E-30 T 28-03-2018 ALX04_RS13190 02bc2f2ace1ffe3f15eed6a06e8c8dbf 443 SUPERFAMILY SSF51905 1 361 2.02E-50 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ALX04_RS13190 02bc2f2ace1ffe3f15eed6a06e8c8dbf 443 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 417 437 2.8E-46 T 28-03-2018 ALX04_RS13190 02bc2f2ace1ffe3f15eed6a06e8c8dbf 443 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 330 351 2.8E-46 T 28-03-2018 ALX04_RS13190 02bc2f2ace1ffe3f15eed6a06e8c8dbf 443 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 6 28 2.8E-46 T 28-03-2018 ALX04_RS13190 02bc2f2ace1ffe3f15eed6a06e8c8dbf 443 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 167 192 2.8E-46 T 28-03-2018 ALX04_RS13190 02bc2f2ace1ffe3f15eed6a06e8c8dbf 443 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 251 265 2.8E-46 T 28-03-2018 ALX04_RS13190 02bc2f2ace1ffe3f15eed6a06e8c8dbf 443 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 38 53 2.8E-46 T 28-03-2018 ALX04_RS13190 02bc2f2ace1ffe3f15eed6a06e8c8dbf 443 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 133 142 2.8E-46 T 28-03-2018 ALX04_RS13190 02bc2f2ace1ffe3f15eed6a06e8c8dbf 443 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 395 410 2.8E-46 T 28-03-2018 ALX04_RS13190 02bc2f2ace1ffe3f15eed6a06e8c8dbf 443 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 293 300 2.8E-46 T 28-03-2018 ALX04_RS13190 02bc2f2ace1ffe3f15eed6a06e8c8dbf 443 Gene3D G3DSA:3.40.50.720 2 37 0.0013 T 28-03-2018 ALX04_RS07405 7538525f5193cbeda9c3554e4424d4e9 331 SUPERFAMILY SSF51905 1 308 2.04E-38 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ALX04_RS07405 7538525f5193cbeda9c3554e4424d4e9 331 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 110 118 2.1E-24 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 ALX04_RS07405 7538525f5193cbeda9c3554e4424d4e9 331 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 6 28 2.1E-24 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 ALX04_RS07405 7538525f5193cbeda9c3554e4424d4e9 331 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 149 173 2.1E-24 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 ALX04_RS07405 7538525f5193cbeda9c3554e4424d4e9 331 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 275 293 2.1E-24 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 ALX04_RS07405 7538525f5193cbeda9c3554e4424d4e9 331 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 63 73 2.1E-24 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 ALX04_RS07405 7538525f5193cbeda9c3554e4424d4e9 331 Gene3D G3DSA:3.50.50.60 1 143 7.5E-22 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ALX04_RS07405 7538525f5193cbeda9c3554e4424d4e9 331 Hamap MF_01685 Ferredoxin--NADP reductase. 4 327 39.964 T 28-03-2018 IPR022890 Ferredoxin--NADP reductase, type 2 GO:0004324|GO:0055114 KEGG: 00195+1.18.1.2|MetaCyc: PWY-101 ALX04_RS07405 7538525f5193cbeda9c3554e4424d4e9 331 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 265 287 1.6E-20 T 28-03-2018 ALX04_RS07405 7538525f5193cbeda9c3554e4424d4e9 331 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 109 127 1.6E-20 T 28-03-2018 ALX04_RS07405 7538525f5193cbeda9c3554e4424d4e9 331 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 153 171 1.6E-20 T 28-03-2018 ALX04_RS07405 7538525f5193cbeda9c3554e4424d4e9 331 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 7 26 1.6E-20 T 28-03-2018 ALX04_RS07405 7538525f5193cbeda9c3554e4424d4e9 331 Gene3D G3DSA:3.40.50.720 147 321 4.6E-14 T 28-03-2018 ALX04_RS07405 7538525f5193cbeda9c3554e4424d4e9 331 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 5 291 5.3E-26 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ALX04_RS03940 039f4b74cfae85f13d92c726250b63b7 347 Pfam PF14493 Helix-turn-helix domain 248 337 2.6E-12 T 28-03-2018 IPR029491 Helicase Helix-turn-helix domain Reactome: R-HSA-3108214|Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473 ALX04_RS03940 039f4b74cfae85f13d92c726250b63b7 347 PIRSF PIRSF021350 1 347 5.8E-120 T 28-03-2018 IPR008308 Uncharacterised conserved protein UCP021350 ALX04_RS11640 94e9ed49d46eb8b2deafad9f5c15f47b 412 ProSitePatterns PS01223 Gamma-glutamyl phosphate reductase signature. 318 339 - T 28-03-2018 IPR020593 Gamma-glutamyl phosphate reductase GPR, conserved site GO:0004350|GO:0006561|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 ALX04_RS11640 94e9ed49d46eb8b2deafad9f5c15f47b 412 PIRSF PIRSF000151 1 412 3.8E-177 T 28-03-2018 IPR012134 Glutamate-5-semialdehyde dehydrogenase GO:0004350|GO:0006561|GO:0050661|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922 ALX04_RS11640 94e9ed49d46eb8b2deafad9f5c15f47b 412 Gene3D G3DSA:3.40.605.10 1 231 3.5E-41 T 28-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 ALX04_RS11640 94e9ed49d46eb8b2deafad9f5c15f47b 412 Pfam PF00171 Aldehyde dehydrogenase family 4 281 2.4E-15 T 28-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 ALX04_RS11640 94e9ed49d46eb8b2deafad9f5c15f47b 412 SUPERFAMILY SSF53720 3 411 1.83E-113 T 28-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 ALX04_RS11640 94e9ed49d46eb8b2deafad9f5c15f47b 412 TIGRFAM TIGR00407 proA: glutamate-5-semialdehyde dehydrogenase 11 401 1.2E-148 T 28-03-2018 IPR000965 GPR domain GO:0004350|GO:0006561|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 ALX04_RS11640 94e9ed49d46eb8b2deafad9f5c15f47b 412 Gene3D G3DSA:3.40.605.10 232 412 1.4E-41 T 28-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 ALX04_RS11640 94e9ed49d46eb8b2deafad9f5c15f47b 412 Hamap MF_00412 Gamma-glutamyl phosphate reductase [proA]. 3 411 41.991 T 28-03-2018 IPR000965 GPR domain GO:0004350|GO:0006561|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 ALX04_RS15350 28ac080f480a9d34189a797ce4cf5558 276 SUPERFAMILY SSF56529 60 275 1.05E-64 T 28-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 ALX04_RS15350 28ac080f480a9d34189a797ce4cf5558 276 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 72 275 4.8E-54 T 28-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 ALX04_RS15350 28ac080f480a9d34189a797ce4cf5558 276 Gene3D G3DSA:3.90.850.10 43 276 1.5E-67 T 28-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 ALX04_RS05660 f8b6ea0babd80c7297c8ae89b18b2158 243 PIRSF PIRSF029008 1 243 1.1E-72 T 28-03-2018 IPR008681 Negative regulator of genetic competence, MecA ALX04_RS05660 f8b6ea0babd80c7297c8ae89b18b2158 243 Hamap MF_01124 Adapter protein MecA [mecA]. 1 242 24.987 T 28-03-2018 IPR008681 Negative regulator of genetic competence, MecA ALX04_RS05660 f8b6ea0babd80c7297c8ae89b18b2158 243 Pfam PF05389 Negative regulator of genetic competence (MecA) 1 238 6.4E-48 T 28-03-2018 IPR008681 Negative regulator of genetic competence, MecA ALX04_RS06470 935ac13618a575d96a0b855bb01a4f9e 288 Pfam PF05175 Methyltransferase small domain 112 202 2.4E-18 T 28-03-2018 IPR007848 Methyltransferase small domain GO:0008168 ALX04_RS06470 935ac13618a575d96a0b855bb01a4f9e 288 Gene3D G3DSA:1.10.8.10 8 85 1.7E-15 T 28-03-2018 ALX04_RS06470 935ac13618a575d96a0b855bb01a4f9e 288 Gene3D G3DSA:3.40.50.150 86 285 3.2E-43 T 28-03-2018 ALX04_RS06470 935ac13618a575d96a0b855bb01a4f9e 288 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 186 192 - T 28-03-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 ALX04_RS06470 935ac13618a575d96a0b855bb01a4f9e 288 Hamap MF_02126 Release factor glutamine methyltransferase [prmC]. 9 283 38.053 T 28-03-2018 IPR019874 Protein-(glutamine-N5) methyltransferase, release factor-specific GO:0008168 ALX04_RS06470 935ac13618a575d96a0b855bb01a4f9e 288 TIGRFAM TIGR00536 hemK_fam: methyltransferase, HemK family 9 279 8.8E-66 T 28-03-2018 IPR004556 Modification methylase HemK GO:0006479|GO:0008276 ALX04_RS06470 935ac13618a575d96a0b855bb01a4f9e 288 TIGRFAM TIGR03534 RF_mod_PrmC: protein-(glutamine-N5) methyltransferase, release factor-specific 30 279 6.6E-84 T 28-03-2018 IPR019874 Protein-(glutamine-N5) methyltransferase, release factor-specific GO:0008168 ALX04_RS06470 935ac13618a575d96a0b855bb01a4f9e 288 SUPERFAMILY SSF53335 9 278 4.03E-51 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase ALX04_RS14140 af7d3bbb02c970b62083c95324066bcd 949 SUPERFAMILY SSF52540 106 342 1.05E-38 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase ALX04_RS14140 af7d3bbb02c970b62083c95324066bcd 949 SUPERFAMILY SSF63520 844 940 9.02E-13 T 28-03-2018 IPR011608 PRD domain GO:0006355 ALX04_RS14140 af7d3bbb02c970b62083c95324066bcd 949 Gene3D G3DSA:3.40.50.300 89 329 1.2E-22 T 28-03-2018 ALX04_RS14140 af7d3bbb02c970b62083c95324066bcd 949 Gene3D G3DSA:1.10.1790.10 827 946 2.6E-8 T 28-03-2018 IPR011608 PRD domain GO:0006355 ALX04_RS14140 af7d3bbb02c970b62083c95324066bcd 949 Gene3D G3DSA:1.10.1790.10 435 561 1.2E-17 T 28-03-2018 IPR011608 PRD domain GO:0006355 ALX04_RS14140 af7d3bbb02c970b62083c95324066bcd 949 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 201 216 - T 28-03-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 ALX04_RS14140 af7d3bbb02c970b62083c95324066bcd 949 Pfam PF03610 PTS system fructose IIA component 575 685 2.0E-13 T 28-03-2018 IPR004701 Phosphotransferase system, mannose-type IIA component GO:0009401|GO:0016021 ALX04_RS14140 af7d3bbb02c970b62083c95324066bcd 949 SUPERFAMILY SSF46785 3 59 9.98E-7 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS14140 af7d3bbb02c970b62083c95324066bcd 949 SMART SM00382 128 278 1.3E-11 T 28-03-2018 IPR003593 AAA+ ATPase domain ALX04_RS14140 af7d3bbb02c970b62083c95324066bcd 949 Pfam PF00158 Sigma-54 interaction domain 105 271 7.1E-48 T 28-03-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 ALX04_RS14140 af7d3bbb02c970b62083c95324066bcd 949 Gene3D G3DSA:1.10.10.10 1 62 1.6E-10 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS14140 af7d3bbb02c970b62083c95324066bcd 949 SUPERFAMILY SSF53062 574 695 2.09E-20 T 28-03-2018 IPR004701 Phosphotransferase system, mannose-type IIA component GO:0009401|GO:0016021 ALX04_RS14140 af7d3bbb02c970b62083c95324066bcd 949 SUPERFAMILY SSF63520 465 565 2.75E-18 T 28-03-2018 IPR011608 PRD domain GO:0006355 ALX04_RS14140 af7d3bbb02c970b62083c95324066bcd 949 Gene3D G3DSA:3.40.50.510 562 707 2.4E-29 T 28-03-2018 IPR004701 Phosphotransferase system, mannose-type IIA component GO:0009401|GO:0016021 ALX04_RS14140 af7d3bbb02c970b62083c95324066bcd 949 Pfam PF00874 PRD domain 480 564 4.5E-14 T 28-03-2018 IPR011608 PRD domain GO:0006355 ALX04_RS14140 af7d3bbb02c970b62083c95324066bcd 949 Pfam PF00874 PRD domain 869 940 1.9E-6 T 28-03-2018 IPR011608 PRD domain GO:0006355 ALX04_RS14140 af7d3bbb02c970b62083c95324066bcd 949 Gene3D G3DSA:3.40.50.2300 720 816 2.8E-8 T 28-03-2018 ALX04_RS09785 4b9e946f0e55123b01ca785c2ed80191 384 SUPERFAMILY SSF53067 82 372 4.89E-27 T 28-03-2018 ALX04_RS09785 4b9e946f0e55123b01ca785c2ed80191 384 SUPERFAMILY SSF46785 7 73 2.25E-13 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS09785 4b9e946f0e55123b01ca785c2ed80191 384 Pfam PF00480 ROK family 84 369 6.2E-31 T 28-03-2018 IPR000600 ROK family Reactome: R-HSA-4085001 ALX04_RS09785 4b9e946f0e55123b01ca785c2ed80191 384 Gene3D G3DSA:3.30.420.40 197 376 1.6E-23 T 28-03-2018 ALX04_RS09785 4b9e946f0e55123b01ca785c2ed80191 384 Gene3D G3DSA:1.10.10.10 8 75 2.7E-5 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS09785 4b9e946f0e55123b01ca785c2ed80191 384 Gene3D G3DSA:3.30.420.40 76 196 4.0E-11 T 28-03-2018 ALX04_RS12165 4852cb5d7e467e9470631b3bf40f6a6b 290 Gene3D G3DSA:3.20.20.100 12 290 8.2E-70 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain ALX04_RS12165 4852cb5d7e467e9470631b3bf40f6a6b 290 PRINTS PR00069 Aldo-keto reductase signature 221 245 1.1E-8 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 ALX04_RS12165 4852cb5d7e467e9470631b3bf40f6a6b 290 PRINTS PR00069 Aldo-keto reductase signature 150 167 1.1E-8 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 ALX04_RS12165 4852cb5d7e467e9470631b3bf40f6a6b 290 PRINTS PR00069 Aldo-keto reductase signature 119 137 1.1E-8 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 ALX04_RS12165 4852cb5d7e467e9470631b3bf40f6a6b 290 Pfam PF00248 Aldo/keto reductase family 22 286 8.5E-55 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain ALX04_RS12165 4852cb5d7e467e9470631b3bf40f6a6b 290 SUPERFAMILY SSF51430 14 287 7.2E-69 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain ALX04_RS14750 93cf5ad7e70dda98ee5d410edd9c2dbb 340 SMART SM00846 3 156 4.6E-85 T 28-03-2018 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 ALX04_RS14750 93cf5ad7e70dda98ee5d410edd9c2dbb 340 Gene3D G3DSA:3.40.50.720 1 165 1.1E-66 T 28-03-2018 ALX04_RS14750 93cf5ad7e70dda98ee5d410edd9c2dbb 340 Gene3D G3DSA:3.30.360.10 166 322 3.4E-50 T 28-03-2018 ALX04_RS14750 93cf5ad7e70dda98ee5d410edd9c2dbb 340 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 273 288 6.9E-27 T 28-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 ALX04_RS14750 93cf5ad7e70dda98ee5d410edd9c2dbb 340 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 114 127 6.9E-27 T 28-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 ALX04_RS14750 93cf5ad7e70dda98ee5d410edd9c2dbb 340 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 150 168 6.9E-27 T 28-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 ALX04_RS14750 93cf5ad7e70dda98ee5d410edd9c2dbb 340 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 177 193 6.9E-27 T 28-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 ALX04_RS14750 93cf5ad7e70dda98ee5d410edd9c2dbb 340 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 235 252 6.9E-27 T 28-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 ALX04_RS14750 93cf5ad7e70dda98ee5d410edd9c2dbb 340 Pfam PF02800 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain 161 320 1.5E-51 T 28-03-2018 IPR020829 Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 ALX04_RS14750 93cf5ad7e70dda98ee5d410edd9c2dbb 340 SUPERFAMILY SSF51735 1 182 4.01E-56 T 28-03-2018 IPR016040 NAD(P)-binding domain ALX04_RS14750 93cf5ad7e70dda98ee5d410edd9c2dbb 340 SUPERFAMILY SSF55347 155 320 3.74E-55 T 28-03-2018 ALX04_RS14750 93cf5ad7e70dda98ee5d410edd9c2dbb 340 PIRSF PIRSF000149 1 340 4.0E-113 T 28-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 ALX04_RS14750 93cf5ad7e70dda98ee5d410edd9c2dbb 340 Pfam PF00044 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain 3 107 7.5E-35 T 28-03-2018 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 ALX04_RS14750 93cf5ad7e70dda98ee5d410edd9c2dbb 340 TIGRFAM TIGR01534 GAPDH-I: glyceraldehyde-3-phosphate dehydrogenase, type I 4 332 4.2E-126 T 28-03-2018 IPR006424 Glyceraldehyde-3-phosphate dehydrogenase, type I GO:0006006|GO:0016620|GO:0050661|GO:0051287|GO:0055114 KEGG: 00010+1.2.1.12|KEGG: 00710+1.2.1.12|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 ALX04_RS00065 b6136fac06db07cd68e250a9d9ffd274 410 Gene3D G3DSA:1.10.10.60 355 401 1.8E-5 T 28-03-2018 ALX04_RS00065 b6136fac06db07cd68e250a9d9ffd274 410 SUPERFAMILY SSF53098 127 324 8.97E-10 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 ALX04_RS00065 b6136fac06db07cd68e250a9d9ffd274 410 Gene3D G3DSA:3.30.420.10 119 328 5.3E-14 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 ALX04_RS06495 c8e6d5f42274ee1b9b657ac3a70b24a7 321 Pfam PF01238 Phosphomannose isomerase type I 7 197 4.6E-43 T 28-03-2018 IPR001250 Mannose-6-phosphate isomerase, type I GO:0004476|GO:0005975|GO:0008270 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-446205 ALX04_RS06495 c8e6d5f42274ee1b9b657ac3a70b24a7 321 Gene3D G3DSA:2.60.120.10 1 223 1.0E-61 T 28-03-2018 IPR014710 RmlC-like jelly roll fold ALX04_RS06495 c8e6d5f42274ee1b9b657ac3a70b24a7 321 PIRSF PIRSF036894 2 318 6.3E-134 T 28-03-2018 IPR014628 Mannose-6-phosphate isomerase, Firmicutes type, short form GO:0004476|GO:0005975 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882 ALX04_RS06495 c8e6d5f42274ee1b9b657ac3a70b24a7 321 TIGRFAM TIGR00218 manA: mannose-6-phosphate isomerase, class I 106 314 1.5E-38 T 28-03-2018 IPR001250 Mannose-6-phosphate isomerase, type I GO:0004476|GO:0005975|GO:0008270 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-446205 ALX04_RS06495 c8e6d5f42274ee1b9b657ac3a70b24a7 321 Gene3D G3DSA:2.60.120.10 236 315 1.8E-14 T 28-03-2018 IPR014710 RmlC-like jelly roll fold ALX04_RS06495 c8e6d5f42274ee1b9b657ac3a70b24a7 321 SUPERFAMILY SSF51182 1 315 1.93E-106 T 28-03-2018 IPR011051 RmlC-like cupin domain ALX04_RS06445 30f852fe64e1323f0a8448e81c061161 426 TIGRFAM TIGR00801 ncs2: uracil-xanthine permease 20 417 7.9E-130 T 28-03-2018 IPR006042 Xanthine/uracil permease GO:0005215|GO:0016020|GO:0055085 Reactome: R-HSA-196836 ALX04_RS06445 30f852fe64e1323f0a8448e81c061161 426 ProSitePatterns PS01116 Xanthine/uracil permeases family signature. 341 361 - T 28-03-2018 IPR006042 Xanthine/uracil permease GO:0005215|GO:0016020|GO:0055085 Reactome: R-HSA-196836 ALX04_RS06445 30f852fe64e1323f0a8448e81c061161 426 Pfam PF00860 Permease family 24 394 4.4E-98 T 28-03-2018 IPR006043 Xanthine/uracil/vitamin C permease GO:0005215|GO:0006810|GO:0016020|GO:0055085 ALX04_RS00365 bcddda0712bbc59bf09cf1299840720c 156 Pfam PF00177 Ribosomal protein S7p/S5e 1 149 2.0E-65 T 28-03-2018 IPR023798 Ribosomal protein S7 domain ALX04_RS00365 bcddda0712bbc59bf09cf1299840720c 156 ProSitePatterns PS00052 Ribosomal protein S7 signature. 20 46 - T 28-03-2018 IPR020606 Ribosomal protein S7, conserved site GO:0003723|GO:0003735|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 ALX04_RS00365 bcddda0712bbc59bf09cf1299840720c 156 Hamap MF_00480_B 30S ribosomal protein S7 [rpsG]. 1 156 35.355 T 28-03-2018 IPR005717 Ribosomal protein S7, bacterial/organellar-type GO:0003735|GO:0006412|GO:0015935 ALX04_RS00365 bcddda0712bbc59bf09cf1299840720c 156 Gene3D G3DSA:1.10.455.10 6 156 2.6E-60 T 28-03-2018 IPR023798 Ribosomal protein S7 domain ALX04_RS00365 bcddda0712bbc59bf09cf1299840720c 156 TIGRFAM TIGR01029 rpsG_bact: ribosomal protein uS7 3 156 3.8E-68 T 28-03-2018 IPR005717 Ribosomal protein S7, bacterial/organellar-type GO:0003735|GO:0006412|GO:0015935 ALX04_RS00365 bcddda0712bbc59bf09cf1299840720c 156 SUPERFAMILY SSF47973 7 149 1.44E-59 T 28-03-2018 IPR023798 Ribosomal protein S7 domain ALX04_RS00365 bcddda0712bbc59bf09cf1299840720c 156 PIRSF PIRSF002122 4 156 2.3E-56 T 28-03-2018 IPR000235 Ribosomal protein S5/S7 GO:0006412 ALX04_RS03300 7f18d84a9cadfc65ceb24f15aa52e376 348 Gene3D G3DSA:3.20.20.70 6 331 3.5E-64 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 ALX04_RS03300 7f18d84a9cadfc65ceb24f15aa52e376 348 Hamap MF_00354 Isopentenyl-diphosphate delta-isomerase [fni]. 6 337 36.49 T 28-03-2018 IPR011179 Isopentenyl-diphosphate delta-isomerase, FMN-dependent GO:0004452|GO:0005737|GO:0008299|GO:0010181 KEGG: 00900+5.3.3.2|MetaCyc: PWY-5123|MetaCyc: PWY-6174|MetaCyc: PWY-6383|MetaCyc: PWY-6859|MetaCyc: PWY-7102|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-7560|MetaCyc: PWY-922 ALX04_RS03300 7f18d84a9cadfc65ceb24f15aa52e376 348 Pfam PF01070 FMN-dependent dehydrogenase 156 330 1.7E-21 T 28-03-2018 IPR000262 FMN-dependent dehydrogenase GO:0016491 ALX04_RS03300 7f18d84a9cadfc65ceb24f15aa52e376 348 SUPERFAMILY SSF51395 26 331 2.01E-75 T 28-03-2018 ALX04_RS03300 7f18d84a9cadfc65ceb24f15aa52e376 348 TIGRFAM TIGR02151 IPP_isom_2: isopentenyl-diphosphate delta-isomerase, type 2 8 328 2.4E-110 T 28-03-2018 IPR011179 Isopentenyl-diphosphate delta-isomerase, FMN-dependent GO:0004452|GO:0005737|GO:0008299|GO:0010181 KEGG: 00900+5.3.3.2|MetaCyc: PWY-5123|MetaCyc: PWY-6174|MetaCyc: PWY-6383|MetaCyc: PWY-6859|MetaCyc: PWY-7102|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-7560|MetaCyc: PWY-922 ALX04_RS03300 7f18d84a9cadfc65ceb24f15aa52e376 348 PIRSF PIRSF003314 3 343 6.9E-123 T 28-03-2018 IPR011179 Isopentenyl-diphosphate delta-isomerase, FMN-dependent GO:0004452|GO:0005737|GO:0008299|GO:0010181 KEGG: 00900+5.3.3.2|MetaCyc: PWY-5123|MetaCyc: PWY-6174|MetaCyc: PWY-6383|MetaCyc: PWY-6859|MetaCyc: PWY-7102|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-7560|MetaCyc: PWY-922 ALX04_RS01680 730de71c4054c3a6b32726d16691bb64 366 Pfam PF00005 ABC transporter 20 162 1.7E-30 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 ALX04_RS01680 730de71c4054c3a6b32726d16691bb64 366 SUPERFAMILY SSF50331 237 350 1.58E-14 T 28-03-2018 IPR008995 Molybdate/tungstate binding, C-terminal ALX04_RS01680 730de71c4054c3a6b32726d16691bb64 366 Pfam PF08402 TOBE domain 274 337 8.0E-6 T 28-03-2018 IPR013611 Transport-associated OB, type 2 GO:0005215|GO:0005524|GO:0006810|GO:0016820|GO:0043190 ALX04_RS01680 730de71c4054c3a6b32726d16691bb64 366 SUPERFAMILY SSF52540 3 245 1.25E-83 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase ALX04_RS01680 730de71c4054c3a6b32726d16691bb64 366 Gene3D G3DSA:3.40.50.300 2 257 1.6E-72 T 28-03-2018 ALX04_RS01680 730de71c4054c3a6b32726d16691bb64 366 SMART SM00382 29 217 4.5E-15 T 28-03-2018 IPR003593 AAA+ ATPase domain ALX04_RS01680 730de71c4054c3a6b32726d16691bb64 366 ProSitePatterns PS00211 ABC transporters family signature. 135 149 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 ALX04_RS01680 730de71c4054c3a6b32726d16691bb64 366 Gene3D G3DSA:2.40.50.140 277 337 2.3E-4 T 28-03-2018 ALX04_RS12160 0a28313150fc11c081e2bf2ea88d184e 282 ProSitePatterns PS00062 Aldo/keto reductase family signature 2. 134 151 - T 28-03-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 ALX04_RS12160 0a28313150fc11c081e2bf2ea88d184e 282 PRINTS PR00069 Aldo-keto reductase signature 95 113 1.8E-41 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 ALX04_RS12160 0a28313150fc11c081e2bf2ea88d184e 282 PRINTS PR00069 Aldo-keto reductase signature 168 197 1.8E-41 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 ALX04_RS12160 0a28313150fc11c081e2bf2ea88d184e 282 PRINTS PR00069 Aldo-keto reductase signature 134 151 1.8E-41 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 ALX04_RS12160 0a28313150fc11c081e2bf2ea88d184e 282 PRINTS PR00069 Aldo-keto reductase signature 205 229 1.8E-41 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 ALX04_RS12160 0a28313150fc11c081e2bf2ea88d184e 282 PRINTS PR00069 Aldo-keto reductase signature 39 63 1.8E-41 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 ALX04_RS12160 0a28313150fc11c081e2bf2ea88d184e 282 SUPERFAMILY SSF51430 6 273 8.12E-83 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain ALX04_RS12160 0a28313150fc11c081e2bf2ea88d184e 282 Pfam PF00248 Aldo/keto reductase family 19 267 3.2E-44 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain ALX04_RS12160 0a28313150fc11c081e2bf2ea88d184e 282 PIRSF PIRSF000097 1 280 7.5E-67 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 ALX04_RS12160 0a28313150fc11c081e2bf2ea88d184e 282 ProSitePatterns PS00798 Aldo/keto reductase family signature 1. 43 60 - T 28-03-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 ALX04_RS12160 0a28313150fc11c081e2bf2ea88d184e 282 Gene3D G3DSA:3.20.20.100 1 281 2.1E-84 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain ALX04_RS16000 4193fdaa9c15ea0d7d6b086670c7e148 34 Pfam PF16935 Putative Holin-like Toxin (Hol-Tox) 1 34 8.5E-16 T 28-03-2018 IPR031616 Putative Holin-like Toxin (Hol-Tox) ALX04_RS12730 36e0c384d633b971d264ed24958f4feb 402 Pfam PF04464 CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase 16 391 3.4E-103 T 28-03-2018 IPR007554 CDP-glycerol glycerophosphotransferase GO:0016020|GO:0047355 ALX04_RS12730 36e0c384d633b971d264ed24958f4feb 402 SUPERFAMILY SSF53756 115 393 4.63E-17 T 28-03-2018 ALX04_RS12730 36e0c384d633b971d264ed24958f4feb 402 Gene3D G3DSA:3.40.50.2000 237 369 0.094 T 28-03-2018 ALX04_RS01675 28358bf25b5ce78ac43702a4ac05326b 168 PRINTS PR01438 Universal stress protein signature 110 122 1.7E-14 T 28-03-2018 IPR006015 Universal stress protein A ALX04_RS01675 28358bf25b5ce78ac43702a4ac05326b 168 PRINTS PR01438 Universal stress protein signature 128 150 1.7E-14 T 28-03-2018 IPR006015 Universal stress protein A ALX04_RS01675 28358bf25b5ce78ac43702a4ac05326b 168 PRINTS PR01438 Universal stress protein signature 4 22 1.7E-14 T 28-03-2018 IPR006015 Universal stress protein A ALX04_RS01675 28358bf25b5ce78ac43702a4ac05326b 168 Gene3D G3DSA:3.40.50.620 1 154 1.1E-28 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold ALX04_RS01675 28358bf25b5ce78ac43702a4ac05326b 168 SUPERFAMILY SSF52402 5 158 1.0E-28 T 28-03-2018 ALX04_RS01675 28358bf25b5ce78ac43702a4ac05326b 168 Pfam PF00582 Universal stress protein family 3 150 1.5E-26 T 28-03-2018 IPR006016 UspA GO:0006950 ALX04_RS03750 0def461032ad2825af0aa0ab1d6861f9 816 Gene3D G3DSA:3.90.199.10 34 215 8.5E-78 T 28-03-2018 IPR013758 DNA topoisomerase, type IIA, subunit A/ C-terminal, alpha-beta GO:0003677|GO:0003918|GO:0005524|GO:0006259|GO:0006265 Reactome: R-HSA-4615885 ALX04_RS03750 0def461032ad2825af0aa0ab1d6861f9 816 Gene3D G3DSA:2.120.10.90 500 813 2.3E-67 T 28-03-2018 ALX04_RS03750 0def461032ad2825af0aa0ab1d6861f9 816 Gene3D G3DSA:3.30.1360.40 236 332 9.8E-30 T 28-03-2018 IPR024946 Arginine repressor C-terminal-like domain Reactome: R-HSA-4615885 ALX04_RS03750 0def461032ad2825af0aa0ab1d6861f9 816 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 550 597 0.097 T 28-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 ALX04_RS03750 0def461032ad2825af0aa0ab1d6861f9 816 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 505 526 0.032 T 28-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 ALX04_RS03750 0def461032ad2825af0aa0ab1d6861f9 816 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 709 751 4.1E-5 T 28-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 ALX04_RS03750 0def461032ad2825af0aa0ab1d6861f9 816 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 608 647 1.5 T 28-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 ALX04_RS03750 0def461032ad2825af0aa0ab1d6861f9 816 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 662 700 3.4E-8 T 28-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 ALX04_RS03750 0def461032ad2825af0aa0ab1d6861f9 816 SUPERFAMILY SSF101904 501 811 9.02E-76 T 28-03-2018 IPR035516 DNA gyrase/topoisomerase IV, subunit A, C-terminal ALX04_RS03750 0def461032ad2825af0aa0ab1d6861f9 816 SUPERFAMILY SSF56719 31 486 4.19E-165 T 28-03-2018 IPR013760 DNA topoisomerase, type IIA-like domain GO:0003918|GO:0005524 Reactome: R-HSA-4615885 ALX04_RS03750 0def461032ad2825af0aa0ab1d6861f9 816 Gene3D G3DSA:1.10.268.10 344 486 6.8E-47 T 28-03-2018 IPR013757 Type IIA DNA topoisomerase subunit A, alpha-helical domain GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 ALX04_RS03750 0def461032ad2825af0aa0ab1d6861f9 816 Pfam PF00521 DNA gyrase/topoisomerase IV, subunit A 32 471 8.6E-149 T 28-03-2018 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 ALX04_RS03750 0def461032ad2825af0aa0ab1d6861f9 816 TIGRFAM TIGR01061 parC_Gpos: DNA topoisomerase IV, A subunit 8 749 0.0 T 28-03-2018 IPR005741 DNA topoisomerase IV subunit A, Gram-positive GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 ALX04_RS03750 0def461032ad2825af0aa0ab1d6861f9 816 SMART SM00434 11 464 2.2E-253 T 28-03-2018 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 ALX04_RS03750 0def461032ad2825af0aa0ab1d6861f9 816 Hamap MF_00937 DNA topoisomerase 4 subunit A [parC]. 7 810 34.223 T 28-03-2018 IPR005741 DNA topoisomerase IV subunit A, Gram-positive GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 ALX04_RS04915 eff056d484b255c70703c329b7432bf5 261 Gene3D G3DSA:3.40.50.300 63 250 7.6E-13 T 28-03-2018 ALX04_RS04915 eff056d484b255c70703c329b7432bf5 261 Pfam PF01695 IstB-like ATP binding protein 99 234 5.2E-13 T 28-03-2018 IPR002611 IstB-like ATP-binding protein GO:0005524 ALX04_RS04915 eff056d484b255c70703c329b7432bf5 261 SMART SM00382 100 256 4.3E-5 T 28-03-2018 IPR003593 AAA+ ATPase domain ALX04_RS04915 eff056d484b255c70703c329b7432bf5 261 SUPERFAMILY SSF52540 80 234 1.94E-14 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase ALX04_RS02450 c67c26c50ad70634942909a57fd8ef0a 320 Pfam PF01545 Cation efflux family 30 239 8.7E-32 T 28-03-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 ALX04_RS02450 c67c26c50ad70634942909a57fd8ef0a 320 Gene3D G3DSA:3.30.70.1350 238 318 3.5E-4 T 28-03-2018 IPR027470 Cation efflux protein, cytoplasmic domain ALX04_RS02450 c67c26c50ad70634942909a57fd8ef0a 320 SUPERFAMILY SSF161111 21 240 1.7E-29 T 28-03-2018 ALX04_RS02450 c67c26c50ad70634942909a57fd8ef0a 320 Gene3D G3DSA:1.20.1510.10 22 237 1.6E-26 T 28-03-2018 ALX04_RS02450 c67c26c50ad70634942909a57fd8ef0a 320 SUPERFAMILY SSF160240 242 317 1.2E-6 T 28-03-2018 ALX04_RS10555 d4523bf68bd02cd6f353fc89f9c8629e 152 Gene3D G3DSA:3.40.630.30 2 151 1.7E-25 T 28-03-2018 ALX04_RS10555 d4523bf68bd02cd6f353fc89f9c8629e 152 Pfam PF13673 Acetyltransferase (GNAT) domain 44 143 3.2E-16 T 28-03-2018 IPR000182 GNAT domain GO:0008080 ALX04_RS10555 d4523bf68bd02cd6f353fc89f9c8629e 152 SUPERFAMILY SSF55729 4 146 1.41E-29 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase ALX04_RS02980 e7effa867a3d317c5c735d2979e709c8 316 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 28 88 3.4E-10 T 28-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 ALX04_RS02980 e7effa867a3d317c5c735d2979e709c8 316 SUPERFAMILY SSF51735 113 267 9.6E-28 T 28-03-2018 IPR016040 NAD(P)-binding domain ALX04_RS02980 e7effa867a3d317c5c735d2979e709c8 316 Gene3D G3DSA:3.40.50.720 149 257 2.6E-14 T 28-03-2018 ALX04_RS02980 e7effa867a3d317c5c735d2979e709c8 316 Gene3D G3DSA:3.90.180.10 2 148 2.3E-40 T 28-03-2018 ALX04_RS02980 e7effa867a3d317c5c735d2979e709c8 316 Pfam PF00107 Zinc-binding dehydrogenase 151 253 3.8E-15 T 28-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 ALX04_RS02980 e7effa867a3d317c5c735d2979e709c8 316 SMART SM00829 10 314 4.9E-11 T 28-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 ALX04_RS02980 e7effa867a3d317c5c735d2979e709c8 316 SUPERFAMILY SSF50129 2 149 2.43E-30 T 28-03-2018 IPR011032 GroES-like ALX04_RS06385 226606501a5136c8869a1cbdfd43b6fa 90 Pfam PF01809 Haemolytic domain 3 68 1.6E-27 T 28-03-2018 IPR002696 Putative membrane protein insertion efficiency factor ALX04_RS06385 226606501a5136c8869a1cbdfd43b6fa 90 SMART SM01234 1 68 1.3E-39 T 28-03-2018 IPR002696 Putative membrane protein insertion efficiency factor ALX04_RS06385 226606501a5136c8869a1cbdfd43b6fa 90 ProDom PD004225 UPF0161 ALPHA-HEMOLYSIN YIDD UNCHARACTERIZED CYTOSOLIC PRECURSOR SIGNAL YTJA RNPA SIMILAR 17 68 1.0E-24 T 28-03-2018 IPR002696 Putative membrane protein insertion efficiency factor ALX04_RS06385 226606501a5136c8869a1cbdfd43b6fa 90 Hamap MF_00386 Putative membrane protein insertion efficiency factor [yidD]. 1 69 23.284 T 28-03-2018 IPR002696 Putative membrane protein insertion efficiency factor ALX04_RS06385 226606501a5136c8869a1cbdfd43b6fa 90 TIGRFAM TIGR00278 TIGR00278: putative membrane protein insertion efficiency factor 5 71 8.0E-27 T 28-03-2018 IPR002696 Putative membrane protein insertion efficiency factor ALX04_RS11790 d1f1b32113c2b94dee378bce5c47f068 471 Pfam PF00939 Sodium:sulfate symporter transmembrane region 6 471 7.0E-123 T 28-03-2018 IPR001898 Solute carrier family 13 GO:0005215|GO:0006814|GO:0016020|GO:0055085 Reactome: R-HSA-433137 ALX04_RS11790 d1f1b32113c2b94dee378bce5c47f068 471 TIGRFAM TIGR00785 dass: transporter, divalent anion:Na+ symporter (DASS) family 31 464 8.2E-106 T 28-03-2018 IPR001898 Solute carrier family 13 GO:0005215|GO:0006814|GO:0016020|GO:0055085 Reactome: R-HSA-433137 ALX04_RS11790 d1f1b32113c2b94dee378bce5c47f068 471 PIRSF PIRSF002457 2 471 7.6E-120 T 28-03-2018 IPR030676 Citrate carrier CitT-related ALX04_RS09345 6ee2c74a3087bb1f9fff1d6ff8162a07 396 SUPERFAMILY SSF89447 8 45 5.06E-5 T 28-03-2018 ALX04_RS09345 6ee2c74a3087bb1f9fff1d6ff8162a07 396 Gene3D G3DSA:2.10.260.10 4 58 1.0E-4 T 28-03-2018 ALX04_RS09955 20cd8ea4806ad1488fdfb5b066e2c882 271 Gene3D G3DSA:3.40.190.10 169 271 1.7E-13 T 28-03-2018 ALX04_RS09955 20cd8ea4806ad1488fdfb5b066e2c882 271 SMART SM00062 48 267 1.3E-58 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF ALX04_RS09955 20cd8ea4806ad1488fdfb5b066e2c882 271 Gene3D G3DSA:3.40.190.10 1 168 9.3E-34 T 28-03-2018 ALX04_RS09955 20cd8ea4806ad1488fdfb5b066e2c882 271 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 49 265 9.8E-57 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF ALX04_RS09955 20cd8ea4806ad1488fdfb5b066e2c882 271 SUPERFAMILY SSF53850 8 267 3.45E-59 T 28-03-2018 ALX04_RS09955 20cd8ea4806ad1488fdfb5b066e2c882 271 ProSitePatterns PS01039 Bacterial extracellular solute-binding proteins, family 3 signature. 70 83 - T 28-03-2018 IPR018313 Solute-binding protein family 3, conserved site GO:0005215|GO:0006810 ALX04_RS05655 4c6f47bb3b7fe7b810329c2d3c244481 361 Pfam PF06054 Competence protein CoiA-like family 21 239 1.9E-39 T 28-03-2018 IPR010330 Competence-induced protein CoiA-like ALX04_RS05655 4c6f47bb3b7fe7b810329c2d3c244481 361 PIRSF PIRSF007487 1 351 3.4E-90 T 28-03-2018 IPR021176 Competence-induced protein CoiA ALX04_RS06005 e1081ae21b5d78768be8f16d4a5bab3b 144 Hamap MF_00651 Putative pre-16S rRNA nuclease [yqgF]. 1 139 26.295 T 28-03-2018 IPR005227 Putative pre-16S rRNA nuclease GO:0006364 ALX04_RS06005 e1081ae21b5d78768be8f16d4a5bab3b 144 Gene3D G3DSA:3.30.420.140 1 144 4.4E-41 T 28-03-2018 IPR006641 YqgF/RNase H-like domain GO:0006139 ALX04_RS06005 e1081ae21b5d78768be8f16d4a5bab3b 144 SUPERFAMILY SSF53098 2 138 2.12E-40 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 ALX04_RS06005 e1081ae21b5d78768be8f16d4a5bab3b 144 TIGRFAM TIGR00250 RNAse_H_YqgF: putative transcription antitermination factor YqgF 4 136 1.1E-40 T 28-03-2018 IPR005227 Putative pre-16S rRNA nuclease GO:0006364 ALX04_RS06005 e1081ae21b5d78768be8f16d4a5bab3b 144 SMART SM00732 1 103 3.8E-32 T 28-03-2018 IPR006641 YqgF/RNase H-like domain GO:0006139 ALX04_RS06005 e1081ae21b5d78768be8f16d4a5bab3b 144 Pfam PF03652 Holliday junction resolvase 1 136 8.0E-40 T 28-03-2018 IPR005227 Putative pre-16S rRNA nuclease GO:0006364 ALX04_RS01065 ffbf182ddca632950bec8ad6eb875b50 532 ProSitePatterns PS00659 Glycosyl hydrolases family 5 signature. 165 174 - T 28-03-2018 IPR018087 Glycoside hydrolase, family 5, conserved site GO:0004553|GO:0005975 ALX04_RS01065 ffbf182ddca632950bec8ad6eb875b50 532 Gene3D G3DSA:3.20.20.80 44 347 2.1E-24 T 28-03-2018 ALX04_RS01065 ffbf182ddca632950bec8ad6eb875b50 532 Pfam PF00150 Cellulase (glycosyl hydrolase family 5) 68 247 2.3E-10 T 28-03-2018 IPR001547 Glycoside hydrolase, family 5 GO:0004553|GO:0005975 ALX04_RS01065 ffbf182ddca632950bec8ad6eb875b50 532 SUPERFAMILY SSF51445 69 344 5.06E-30 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily ALX04_RS08975 2921ceb15268c32635607a1412deec0a 88 SUPERFAMILY SSF109797 7 82 6.28E-5 T 28-03-2018 ALX04_RS08975 2921ceb15268c32635607a1412deec0a 88 Pfam PF08951 Enterocin A Immunity 9 75 1.7E-6 T 28-03-2018 IPR015046 Enterocin A Immunity ALX04_RS06285 997ff17a1fd3ef93c7fc3a220f395ca1 155 Gene3D G3DSA:3.40.35.10 2 155 3.8E-47 T 28-03-2018 IPR004720 Phosphotransferase system, sorbose subfamily IIB component GO:0005737|GO:0008982|GO:0009401 ALX04_RS06285 997ff17a1fd3ef93c7fc3a220f395ca1 155 SUPERFAMILY SSF52728 1 153 7.32E-46 T 28-03-2018 IPR004720 Phosphotransferase system, sorbose subfamily IIB component GO:0005737|GO:0008982|GO:0009401 ALX04_RS06285 997ff17a1fd3ef93c7fc3a220f395ca1 155 Pfam PF03830 PTS system sorbose subfamily IIB component 4 149 3.8E-44 T 28-03-2018 IPR004720 Phosphotransferase system, sorbose subfamily IIB component GO:0005737|GO:0008982|GO:0009401 ALX04_RS12935 7264740e1a73cc3627c5ed0ee75ee737 147 SUPERFAMILY SSF55729 2 144 3.01E-29 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase ALX04_RS12935 7264740e1a73cc3627c5ed0ee75ee737 147 Gene3D G3DSA:3.40.630.30 1 147 7.2E-25 T 28-03-2018 ALX04_RS12935 7264740e1a73cc3627c5ed0ee75ee737 147 Pfam PF13673 Acetyltransferase (GNAT) domain 23 141 3.0E-18 T 28-03-2018 IPR000182 GNAT domain GO:0008080 ALX04_RS10380 8de8a1feda1536e28dcb70b333e336a8 329 SUPERFAMILY SSF56601 4 324 2.17E-70 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like ALX04_RS10380 8de8a1feda1536e28dcb70b333e336a8 329 Pfam PF00144 Beta-lactamase 8 318 5.5E-44 T 28-03-2018 IPR001466 Beta-lactamase-related ALX04_RS10380 8de8a1feda1536e28dcb70b333e336a8 329 Gene3D G3DSA:3.40.710.10 2 325 1.8E-60 T 28-03-2018 ALX04_RS15680 8bf8924d2f9b75e02905ca5ff0db4675 89 Gene3D G3DSA:1.10.10.60 1 52 8.1E-13 T 28-03-2018 ALX04_RS15680 8bf8924d2f9b75e02905ca5ff0db4675 89 SMART SM00530 32 86 2.8E-11 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 ALX04_RS15680 8bf8924d2f9b75e02905ca5ff0db4675 89 Gene3D G3DSA:3.30.1190.10 53 89 1.2E-12 T 28-03-2018 ALX04_RS15680 8bf8924d2f9b75e02905ca5ff0db4675 89 Pfam PF01381 Helix-turn-helix 36 83 2.1E-14 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 ALX04_RS15680 8bf8924d2f9b75e02905ca5ff0db4675 89 SUPERFAMILY SSF47413 30 87 1.41E-15 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 ALX04_RS01440 4b8c6751addc9fb1dd9cfbb172812246 395 SUPERFAMILY SSF53383 9 388 4.17E-106 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase ALX04_RS01440 4b8c6751addc9fb1dd9cfbb172812246 395 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 235 248 - T 28-03-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 ALX04_RS01440 4b8c6751addc9fb1dd9cfbb172812246 395 Pfam PF00155 Aminotransferase class I and II 32 383 2.9E-68 T 28-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 ALX04_RS01440 4b8c6751addc9fb1dd9cfbb172812246 395 Gene3D G3DSA:3.90.1150.10 301 391 2.3E-24 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 ALX04_RS01440 4b8c6751addc9fb1dd9cfbb172812246 395 Gene3D G3DSA:3.40.640.10 46 300 2.5E-55 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 ALX04_RS03995 13ed57414776e24cb7f7c29b9027e741 320 SUPERFAMILY SSF53784 1 310 3.4E-104 T 28-03-2018 IPR000023 Phosphofructokinase domain GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 ALX04_RS03995 13ed57414776e24cb7f7c29b9027e741 320 ProSitePatterns PS00433 Phosphofructokinase signature. 243 261 - T 28-03-2018 IPR015912 Phosphofructokinase, conserved site GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 ALX04_RS03995 13ed57414776e24cb7f7c29b9027e741 320 Pfam PF00365 Phosphofructokinase 3 275 4.6E-99 T 28-03-2018 IPR000023 Phosphofructokinase domain GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 ALX04_RS03995 13ed57414776e24cb7f7c29b9027e741 320 PIRSF PIRSF000532 1 319 2.4E-110 T 28-03-2018 IPR012003 ATP-dependent 6-phosphofructokinase, prokaryotic-type GO:0005524|GO:0006002|GO:0006096|GO:0008443 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385 ALX04_RS03995 13ed57414776e24cb7f7c29b9027e741 320 Hamap MF_00339 ATP-dependent 6-phosphofructokinase [pfkA]. 1 318 46.482 T 28-03-2018 IPR012828 ATP-dependent 6-phosphofructokinase, prokaryotic GO:0003872|GO:0005524|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385 ALX04_RS03995 13ed57414776e24cb7f7c29b9027e741 320 Gene3D G3DSA:3.40.50.450 1 226 1.5E-78 T 28-03-2018 ALX04_RS03995 13ed57414776e24cb7f7c29b9027e741 320 TIGRFAM TIGR02482 PFKA_ATP: 6-phosphofructokinase 3 298 1.7E-117 T 28-03-2018 IPR012828 ATP-dependent 6-phosphofructokinase, prokaryotic GO:0003872|GO:0005524|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385 ALX04_RS03995 13ed57414776e24cb7f7c29b9027e741 320 Gene3D G3DSA:3.40.50.450 227 309 6.3E-6 T 28-03-2018 ALX04_RS03995 13ed57414776e24cb7f7c29b9027e741 320 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 120 137 1.0E-73 T 28-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 ALX04_RS03995 13ed57414776e24cb7f7c29b9027e741 320 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 158 174 1.0E-73 T 28-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 ALX04_RS03995 13ed57414776e24cb7f7c29b9027e741 320 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 212 224 1.0E-73 T 28-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 ALX04_RS03995 13ed57414776e24cb7f7c29b9027e741 320 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 138 156 1.0E-73 T 28-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 ALX04_RS03995 13ed57414776e24cb7f7c29b9027e741 320 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 31 44 1.0E-73 T 28-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 ALX04_RS03995 13ed57414776e24cb7f7c29b9027e741 320 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 93 109 1.0E-73 T 28-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 ALX04_RS03995 13ed57414776e24cb7f7c29b9027e741 320 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 239 261 1.0E-73 T 28-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 ALX04_RS03995 13ed57414776e24cb7f7c29b9027e741 320 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 6 25 1.0E-73 T 28-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 ALX04_RS03995 13ed57414776e24cb7f7c29b9027e741 320 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 176 193 1.0E-73 T 28-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 ALX04_RS12320 a00871bafa7003819a0cf4849b81c0c1 429 Gene3D G3DSA:1.20.58.370 28 155 4.1E-9 T 28-03-2018 IPR035277 Maltose transport system permease protein MalF N-terminal domain ALX04_RS12320 a00871bafa7003819a0cf4849b81c0c1 429 SUPERFAMILY SSF160964 64 83 1.7E-7 T 28-03-2018 ALX04_RS12320 a00871bafa7003819a0cf4849b81c0c1 429 SUPERFAMILY SSF160964 118 173 1.7E-7 T 28-03-2018 ALX04_RS12320 a00871bafa7003819a0cf4849b81c0c1 429 SUPERFAMILY SSF161098 170 417 4.06E-45 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 ALX04_RS12320 a00871bafa7003819a0cf4849b81c0c1 429 Gene3D G3DSA:1.10.3720.10 179 421 2.6E-38 T 28-03-2018 ALX04_RS12320 a00871bafa7003819a0cf4849b81c0c1 429 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 205 420 6.0E-20 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 ALX04_RS13765 06fec45a771ce4604ab7fe29ea812d49 341 Pfam PF01118 Semialdehyde dehydrogenase, NAD binding domain 2 132 2.0E-20 T 28-03-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 ALX04_RS13765 06fec45a771ce4604ab7fe29ea812d49 341 SUPERFAMILY SSF51735 2 174 1.28E-29 T 28-03-2018 IPR016040 NAD(P)-binding domain ALX04_RS13765 06fec45a771ce4604ab7fe29ea812d49 341 Pfam PF02774 Semialdehyde dehydrogenase, dimerisation domain 155 312 3.1E-32 T 28-03-2018 IPR012280 Semialdehyde dehydrogenase, dimerisation domain GO:0003942|GO:0005737|GO:0008652|GO:0016620|GO:0046983|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 ALX04_RS13765 06fec45a771ce4604ab7fe29ea812d49 341 TIGRFAM TIGR01850 argC: N-acetyl-gamma-glutamyl-phosphate reductase 1 341 3.8E-117 T 28-03-2018 IPR000706 N-acetyl-gamma-glutamyl-phosphate reductase, type 1 GO:0003942|GO:0006526|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 ALX04_RS13765 06fec45a771ce4604ab7fe29ea812d49 341 Gene3D G3DSA:3.30.360.10 156 309 2.2E-54 T 28-03-2018 ALX04_RS13765 06fec45a771ce4604ab7fe29ea812d49 341 Hamap MF_00150 N-acetyl-gamma-glutamyl-phosphate reductase [argC]. 1 335 36.936 T 28-03-2018 IPR000706 N-acetyl-gamma-glutamyl-phosphate reductase, type 1 GO:0003942|GO:0006526|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 ALX04_RS13765 06fec45a771ce4604ab7fe29ea812d49 341 SUPERFAMILY SSF55347 146 309 3.01E-48 T 28-03-2018 ALX04_RS13765 06fec45a771ce4604ab7fe29ea812d49 341 Gene3D G3DSA:3.40.50.720 1 155 3.8E-24 T 28-03-2018 ALX04_RS13765 06fec45a771ce4604ab7fe29ea812d49 341 ProSitePatterns PS01224 N-acetyl-gamma-glutamyl-phosphate reductase active site. 141 157 - T 28-03-2018 IPR023013 N-acetyl-gamma-glutamyl-phosphate reductase, active site GO:0003942|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 ALX04_RS13765 06fec45a771ce4604ab7fe29ea812d49 341 SMART SM00859 2 140 3.5E-17 T 28-03-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 ALX04_RS09775 e1823a47ec321b232ed280630730a10f 230 SUPERFAMILY SSF53254 1 221 5.44E-73 T 28-03-2018 IPR029033 Histidine phosphatase superfamily ALX04_RS09775 e1823a47ec321b232ed280630730a10f 230 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 4 122 1.0E-27 T 28-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 ALX04_RS09775 e1823a47ec321b232ed280630730a10f 230 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 138 219 1.5E-5 T 28-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 ALX04_RS09775 e1823a47ec321b232ed280630730a10f 230 ProSitePatterns PS00175 Phosphoglycerate mutase family phosphohistidine signature. 6 15 - T 28-03-2018 IPR001345 Phosphoglycerate/bisphosphoglycerate mutase, active site GO:0003824|GO:0008152 ALX04_RS09775 e1823a47ec321b232ed280630730a10f 230 Gene3D G3DSA:3.40.50.1240 1 230 1.4E-59 T 28-03-2018 IPR029033 Histidine phosphatase superfamily ALX04_RS09775 e1823a47ec321b232ed280630730a10f 230 PIRSF PIRSF000709 173 218 1.9 T 28-03-2018 ALX04_RS09775 e1823a47ec321b232ed280630730a10f 230 PIRSF PIRSF000709 2 112 1.7E-8 T 28-03-2018 ALX04_RS09775 e1823a47ec321b232ed280630730a10f 230 TIGRFAM TIGR01258 pgm_1: phosphoglycerate mutase 1 family 3 228 5.1E-109 T 28-03-2018 IPR005952 Phosphoglycerate mutase 1 GO:0004619|GO:0006096|GO:0016868 KEGG: 00010+5.4.2.11|KEGG: 00260+5.4.2.11|KEGG: 00680+5.4.2.11|MetaCyc: PWY-1622|MetaCyc: PWY-5484 ALX04_RS09775 e1823a47ec321b232ed280630730a10f 230 Hamap MF_01039 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [gpmA]. 1 228 45.182 T 28-03-2018 IPR005952 Phosphoglycerate mutase 1 GO:0004619|GO:0006096|GO:0016868 KEGG: 00010+5.4.2.11|KEGG: 00260+5.4.2.11|KEGG: 00680+5.4.2.11|MetaCyc: PWY-1622|MetaCyc: PWY-5484 ALX04_RS09775 e1823a47ec321b232ed280630730a10f 230 SMART SM00855 3 189 3.6E-26 T 28-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 ALX04_RS02860 9572379eb51505d8b88bc694d6c9f92c 81 Gene3D G3DSA:1.10.1200.10 1 81 1.2E-23 T 28-03-2018 ALX04_RS02860 9572379eb51505d8b88bc694d6c9f92c 81 Hamap MF_01217 Acyl carrier protein [acpP]. 5 79 18.714 T 28-03-2018 IPR003231 Acyl carrier protein (ACP) GO:0006633 Reactome: R-HSA-389661|Reactome: R-HSA-611105|Reactome: R-HSA-6799198|Reactome: R-HSA-77289 ALX04_RS02860 9572379eb51505d8b88bc694d6c9f92c 81 ProDom PD000887 CARRIER ACYL PHOSPHOPANTETHEINE ACP ACID FATTY BIOSYNTHESIS LIPID SYNTHESIS CHLOROPLAST 36 78 1.0E-16 T 28-03-2018 IPR003231 Acyl carrier protein (ACP) GO:0006633 Reactome: R-HSA-389661|Reactome: R-HSA-611105|Reactome: R-HSA-6799198|Reactome: R-HSA-77289 ALX04_RS02860 9572379eb51505d8b88bc694d6c9f92c 81 TIGRFAM TIGR00517 acyl_carrier: acyl carrier protein 4 79 1.8E-24 T 28-03-2018 IPR003231 Acyl carrier protein (ACP) GO:0006633 Reactome: R-HSA-389661|Reactome: R-HSA-611105|Reactome: R-HSA-6799198|Reactome: R-HSA-77289 ALX04_RS02860 9572379eb51505d8b88bc694d6c9f92c 81 SUPERFAMILY SSF47336 1 79 1.7E-21 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain ALX04_RS02860 9572379eb51505d8b88bc694d6c9f92c 81 Pfam PF00550 Phosphopantetheine attachment site 8 75 1.2E-13 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain ALX04_RS14205 92565f94126fd1f76f48e32a516ee354 443 SUPERFAMILY SSF54001 4 443 2.12E-141 T 28-03-2018 ALX04_RS14205 92565f94126fd1f76f48e32a516ee354 443 ProSitePatterns PS00139 Eukaryotic thiol (cysteine) proteases cysteine active site. 64 75 - T 28-03-2018 IPR000169 Cysteine peptidase, cysteine active site ALX04_RS14205 92565f94126fd1f76f48e32a516ee354 443 ProSitePatterns PS00639 Eukaryotic thiol (cysteine) proteases histidine active site. 362 372 - T 28-03-2018 IPR025660 Cysteine peptidase, histidine active site Reactome: R-HSA-2132295 ALX04_RS14205 92565f94126fd1f76f48e32a516ee354 443 Pfam PF03051 Peptidase C1-like family 5 440 7.7E-203 T 28-03-2018 IPR004134 Peptidase C1B, bleomycin hydrolase GO:0004197|GO:0006508 Reactome: R-HSA-983168 ALX04_RS14205 92565f94126fd1f76f48e32a516ee354 443 Gene3D G3DSA:3.90.70.10 53 443 4.2E-136 T 28-03-2018 ALX04_RS14205 92565f94126fd1f76f48e32a516ee354 443 PIRSF PIRSF005700 1 443 3.2E-183 T 28-03-2018 IPR004134 Peptidase C1B, bleomycin hydrolase GO:0004197|GO:0006508 Reactome: R-HSA-983168 ALX04_RS15890 f8575f8738545e8e3eb23fbe7140bed9 309 Gene3D G3DSA:1.10.10.10 60 135 2.8E-6 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS15890 f8575f8738545e8e3eb23fbe7140bed9 309 Pfam PF00665 Integrase core domain 160 259 1.8E-16 T 28-03-2018 IPR001584 Integrase, catalytic core GO:0015074 ALX04_RS15890 f8575f8738545e8e3eb23fbe7140bed9 309 Gene3D G3DSA:1.10.10.60 2 48 1.1E-8 T 28-03-2018 ALX04_RS15890 f8575f8738545e8e3eb23fbe7140bed9 309 SUPERFAMILY SSF53098 158 300 6.83E-28 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 ALX04_RS15890 f8575f8738545e8e3eb23fbe7140bed9 309 Gene3D G3DSA:3.30.420.10 157 309 1.2E-25 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 ALX04_RS15890 f8575f8738545e8e3eb23fbe7140bed9 309 Pfam PF13936 Helix-turn-helix domain 4 42 8.3E-9 T 28-03-2018 IPR025246 Transposase IS30-like HTH domain ALX04_RS02395 ad639b6e6abc0cf8f9db2e2eeaf4c595 176 Gene3D G3DSA:3.40.50.1000 37 164 1.2E-22 T 28-03-2018 IPR023214 HAD-like domain ALX04_RS02395 ad639b6e6abc0cf8f9db2e2eeaf4c595 176 SUPERFAMILY SSF56784 7 139 1.27E-26 T 28-03-2018 IPR023214 HAD-like domain ALX04_RS02395 ad639b6e6abc0cf8f9db2e2eeaf4c595 176 Gene3D G3DSA:3.40.50.1000 12 36 0.036 T 28-03-2018 IPR023214 HAD-like domain ALX04_RS02395 ad639b6e6abc0cf8f9db2e2eeaf4c595 176 TIGRFAM TIGR01662 HAD-SF-IIIA: HAD hydrolase, family IIIA 28 138 2.2E-15 T 28-03-2018 IPR006549 HAD-superfamily hydrolase,subfamily IIIA Reactome: R-HSA-5649702 ALX04_RS02395 ad639b6e6abc0cf8f9db2e2eeaf4c595 176 Pfam PF00702 haloacid dehalogenase-like hydrolase 10 130 4.0E-11 T 28-03-2018 ALX04_RS02395 ad639b6e6abc0cf8f9db2e2eeaf4c595 176 TIGRFAM TIGR01668 YqeG_hyp_ppase: HAD phosphatase, family IIIA 5 161 1.5E-37 T 28-03-2018 IPR010021 HAD-superfamily phosphatase, YqeG-like ALX04_RS13825 ce44bbdecf300d665e39969d8c8454ec 95 Pfam PF01479 S4 domain 3 48 3.3E-11 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 ALX04_RS13825 ce44bbdecf300d665e39969d8c8454ec 95 PIRSF PIRSF038881 3 90 3.5E-32 T 28-03-2018 IPR025490 RNA-binding protein, HP1423 type ALX04_RS13825 ce44bbdecf300d665e39969d8c8454ec 95 SMART SM00363 3 63 6.0E-8 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 ALX04_RS13825 ce44bbdecf300d665e39969d8c8454ec 95 Gene3D G3DSA:3.10.290.10 1 92 1.4E-15 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 ALX04_RS13825 ce44bbdecf300d665e39969d8c8454ec 95 SUPERFAMILY SSF55174 2 79 1.14E-20 T 28-03-2018 ALX04_RS07360 6be80a3e7302117edeb9b2d1cb8ed084 317 Pfam PF02275 Linear amide C-N hydrolases, choloylglycine hydrolase family 2 287 1.0E-44 T 28-03-2018 IPR029132 Choloylglycine hydrolase/NAAA C-terminal ALX04_RS07360 6be80a3e7302117edeb9b2d1cb8ed084 317 Gene3D G3DSA:3.60.60.10 1 307 1.1E-47 T 28-03-2018 ALX04_RS07360 6be80a3e7302117edeb9b2d1cb8ed084 317 SUPERFAMILY SSF56235 2 309 4.94E-72 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal ALX04_RS07300 4746723227bbf33218af8c0162291b85 194 ProSitePatterns PS00954 Imidazoleglycerol-phosphate dehydratase signature 1. 61 74 - T 28-03-2018 IPR020565 Imidazoleglycerol-phosphate dehydratase, conserved site GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 ALX04_RS07300 4746723227bbf33218af8c0162291b85 194 Gene3D G3DSA:3.30.230.40 90 194 1.3E-29 T 28-03-2018 ALX04_RS07300 4746723227bbf33218af8c0162291b85 194 Pfam PF00475 Imidazoleglycerol-phosphate dehydratase 31 174 5.0E-62 T 28-03-2018 IPR000807 Imidazoleglycerol-phosphate dehydratase GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 ALX04_RS07300 4746723227bbf33218af8c0162291b85 194 SUPERFAMILY SSF54211 2 85 6.58E-32 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold ALX04_RS07300 4746723227bbf33218af8c0162291b85 194 Gene3D G3DSA:3.30.230.40 2 88 2.9E-35 T 28-03-2018 ALX04_RS07300 4746723227bbf33218af8c0162291b85 194 SUPERFAMILY SSF54211 87 179 1.39E-33 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold ALX04_RS07300 4746723227bbf33218af8c0162291b85 194 Hamap MF_00076 Imidazoleglycerol-phosphate dehydratase [hisB]. 2 194 40.393 T 28-03-2018 IPR000807 Imidazoleglycerol-phosphate dehydratase GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 ALX04_RS07300 4746723227bbf33218af8c0162291b85 194 ProSitePatterns PS00955 Imidazoleglycerol-phosphate dehydratase signature 2. 156 168 - T 28-03-2018 IPR020565 Imidazoleglycerol-phosphate dehydratase, conserved site GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 ALX04_RS08490 1aea559dbf21e4f3347e666ffd43a83c 106 Gene3D G3DSA:1.20.1290.10 1 106 1.0E-27 T 28-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 ALX04_RS08490 1aea559dbf21e4f3347e666ffd43a83c 106 Pfam PF02627 Carboxymuconolactone decarboxylase family 17 102 7.6E-19 T 28-03-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 ALX04_RS08490 1aea559dbf21e4f3347e666ffd43a83c 106 SUPERFAMILY SSF69118 9 106 1.06E-26 T 28-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 ALX04_RS05090 e224a63d46fbaa4b71bd81994843793e 431 Gene3D G3DSA:3.40.50.300 158 339 2.3E-29 T 28-03-2018 ALX04_RS05090 e224a63d46fbaa4b71bd81994843793e 431 Hamap MF_01454 GTPase Obg [obg]. 1 335 46.92 T 28-03-2018 IPR014100 GTP-binding protein Obg/CgtA GO:0000287|GO:0003924|GO:0005525 ALX04_RS05090 e224a63d46fbaa4b71bd81994843793e 431 TIGRFAM TIGR02729 Obg_CgtA: Obg family GTPase CgtA 2 334 2.1E-140 T 28-03-2018 IPR014100 GTP-binding protein Obg/CgtA GO:0000287|GO:0003924|GO:0005525 ALX04_RS05090 e224a63d46fbaa4b71bd81994843793e 431 SUPERFAMILY SSF82051 1 157 1.15E-54 T 28-03-2018 IPR006169 GTP1/OBG domain ALX04_RS05090 e224a63d46fbaa4b71bd81994843793e 431 TIGRFAM TIGR03595 Obg_CgtA_exten: Obg family GTPase CgtA, C-terminal extension 361 430 1.3E-24 T 28-03-2018 IPR015349 GTP-binding protein OBG, C-terminal GO:0000166 ALX04_RS05090 e224a63d46fbaa4b71bd81994843793e 431 Pfam PF01926 50S ribosome-binding GTPase 160 283 7.6E-22 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 ALX04_RS05090 e224a63d46fbaa4b71bd81994843793e 431 Gene3D G3DSA:2.70.210.12 1 155 2.1E-55 T 28-03-2018 IPR006169 GTP1/OBG domain ALX04_RS05090 e224a63d46fbaa4b71bd81994843793e 431 ProSitePatterns PS00905 GTP1/OBG family signature. 212 225 - T 28-03-2018 IPR006074 GTP1/OBG, conserved site GO:0005525 ALX04_RS05090 e224a63d46fbaa4b71bd81994843793e 431 Pfam PF01018 GTP1/OBG 3 157 3.2E-58 T 28-03-2018 IPR006169 GTP1/OBG domain ALX04_RS05090 e224a63d46fbaa4b71bd81994843793e 431 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 227 245 1.5E-33 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 ALX04_RS05090 e224a63d46fbaa4b71bd81994843793e 431 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 182 200 1.5E-33 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 ALX04_RS05090 e224a63d46fbaa4b71bd81994843793e 431 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 161 181 1.5E-33 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 ALX04_RS05090 e224a63d46fbaa4b71bd81994843793e 431 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 210 225 1.5E-33 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 ALX04_RS05090 e224a63d46fbaa4b71bd81994843793e 431 SUPERFAMILY SSF52540 151 338 9.81E-50 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase ALX04_RS05090 e224a63d46fbaa4b71bd81994843793e 431 SUPERFAMILY SSF102741 359 431 9.81E-21 T 28-03-2018 IPR015349 GTP-binding protein OBG, C-terminal GO:0000166 ALX04_RS05090 e224a63d46fbaa4b71bd81994843793e 431 Pfam PF09269 Domain of unknown function (DUF1967) 361 429 1.6E-23 T 28-03-2018 IPR015349 GTP-binding protein OBG, C-terminal GO:0000166 ALX04_RS06475 6a587487e88d3ca09f4c5896479bc515 360 SMART SM00937 66 180 7.8E-61 T 28-03-2018 IPR005139 Peptide chain release factor GO:0006415 ALX04_RS06475 6a587487e88d3ca09f4c5896479bc515 360 Gene3D G3DSA:3.30.160.20 210 292 4.5E-32 T 28-03-2018 ALX04_RS06475 6a587487e88d3ca09f4c5896479bc515 360 Pfam PF00472 RF-1 domain 213 322 1.3E-41 T 28-03-2018 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 ALX04_RS06475 6a587487e88d3ca09f4c5896479bc515 360 Pfam PF03462 PCRF domain 12 205 9.4E-72 T 28-03-2018 IPR005139 Peptide chain release factor GO:0006415 ALX04_RS06475 6a587487e88d3ca09f4c5896479bc515 360 TIGRFAM TIGR00019 prfA: peptide chain release factor 1 3 358 8.7E-161 T 28-03-2018 IPR004373 Peptide chain release factor 1 GO:0005737|GO:0006415|GO:0016149 ALX04_RS06475 6a587487e88d3ca09f4c5896479bc515 360 Hamap MF_00093 Peptide chain release factor 1 [prfA]. 4 358 39.768 T 28-03-2018 IPR004373 Peptide chain release factor 1 GO:0005737|GO:0006415|GO:0016149 ALX04_RS06475 6a587487e88d3ca09f4c5896479bc515 360 Gene3D G3DSA:1.20.58.410 1 102 2.8E-17 T 28-03-2018 ALX04_RS06475 6a587487e88d3ca09f4c5896479bc515 360 ProSitePatterns PS00745 Prokaryotic-type class I peptide chain release factors signature. 229 245 - T 28-03-2018 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 ALX04_RS06475 6a587487e88d3ca09f4c5896479bc515 360 SUPERFAMILY SSF75620 11 354 1.19E-131 T 28-03-2018 ALX04_RS11300 9eb557b290b68515c6219fed08a9da9a 474 SUPERFAMILY SSF50443 327 472 1.28E-55 T 28-03-2018 IPR004216 L-fucose/L-arabinose isomerase, C-terminal ALX04_RS11300 9eb557b290b68515c6219fed08a9da9a 474 Pfam PF11762 L-arabinose isomerase C-terminal domain 360 469 1.1E-43 T 28-03-2018 IPR024664 L-arabinose isomerase, C-terminal KEGG: 00040+5.3.1.4 ALX04_RS11300 9eb557b290b68515c6219fed08a9da9a 474 PIRSF PIRSF001478 1 474 3.4E-237 T 28-03-2018 IPR003762 L-arabinose isomerase GO:0008152|GO:0008733 KEGG: 00040+5.3.1.4 ALX04_RS11300 9eb557b290b68515c6219fed08a9da9a 474 Hamap MF_00519 L-arabinose isomerase [araA]. 1 474 58.829 T 28-03-2018 IPR003762 L-arabinose isomerase GO:0008152|GO:0008733 KEGG: 00040+5.3.1.4 ALX04_RS11300 9eb557b290b68515c6219fed08a9da9a 474 Pfam PF02610 L-arabinose isomerase 6 357 1.4E-165 T 28-03-2018 IPR003762 L-arabinose isomerase GO:0008152|GO:0008733 KEGG: 00040+5.3.1.4 ALX04_RS11300 9eb557b290b68515c6219fed08a9da9a 474 SUPERFAMILY SSF53743 1 326 1.33E-121 T 28-03-2018 IPR009015 L-fucose isomerase, N-terminal/central domain GO:0005737|GO:0005996|GO:0016861 ALX04_RS11300 9eb557b290b68515c6219fed08a9da9a 474 ProDom PD018364 ISOMERASE L-ARABINOSE ARABINOSE METABOLISM CARBOHYDRATE CATABOLISM ARAA 8 304 6.0E-176 T 28-03-2018 IPR003762 L-arabinose isomerase GO:0008152|GO:0008733 KEGG: 00040+5.3.1.4 ALX04_RS12965 84cc7003f9855e417577c666d55fd34e 277 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 58 272 3.8E-14 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 ALX04_RS12965 84cc7003f9855e417577c666d55fd34e 277 SUPERFAMILY SSF161098 12 264 1.59E-47 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 ALX04_RS12965 84cc7003f9855e417577c666d55fd34e 277 Gene3D G3DSA:1.10.3720.10 10 274 9.2E-39 T 28-03-2018 ALX04_RS00855 88cbf3b2aadfc12f8135610b6f882d6c 389 Gene3D G3DSA:3.30.470.20 186 372 9.3E-26 T 28-03-2018 ALX04_RS00855 88cbf3b2aadfc12f8135610b6f882d6c 389 SUPERFAMILY SSF52440 6 105 5.9E-15 T 28-03-2018 IPR016185 Pre-ATP-grasp domain ALX04_RS00855 88cbf3b2aadfc12f8135610b6f882d6c 389 Pfam PF02222 ATP-grasp domain 116 279 2.9E-25 T 28-03-2018 IPR003135 ATP-grasp fold, ATP-dependent carboxylate-amine ligase-type ALX04_RS00855 88cbf3b2aadfc12f8135610b6f882d6c 389 Gene3D G3DSA:3.40.50.20 11 102 6.9E-14 T 28-03-2018 ALX04_RS00855 88cbf3b2aadfc12f8135610b6f882d6c 389 Gene3D G3DSA:3.30.1490.20 103 185 1.6E-7 T 28-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 ALX04_RS00855 88cbf3b2aadfc12f8135610b6f882d6c 389 SUPERFAMILY SSF56059 107 301 2.6E-42 T 28-03-2018 ALX04_RS08960 b74c78ee5466a359866e0c1724cedd43 482 Pfam PF13240 zinc-ribbon domain 20 42 1.6E-6 T 28-03-2018 IPR026870 Zinc-ribbon domain Reactome: R-HSA-202670 ALX04_RS08960 b74c78ee5466a359866e0c1724cedd43 482 Gene3D G3DSA:2.20.28.20 19 46 1.1E-5 T 28-03-2018 ALX04_RS08960 b74c78ee5466a359866e0c1724cedd43 482 ProDom PD057827 ZN-RIBBON HI1126 PM0127 TRANSMEMBRANE ORF196EGC129 MEMBRANE SO2423 GLL0157 21 47 0.005 T 28-03-2018 ALX04_RS14480 a3f85e26ed20bbf5bf58d4b7f2d97617 225 Pfam PF06971 Putative DNA-binding protein N-terminus 5 53 1.9E-19 T 28-03-2018 IPR009718 Rex DNA-binding, C-terminal domain GO:0005737|GO:0045892|GO:0051775 ALX04_RS14480 a3f85e26ed20bbf5bf58d4b7f2d97617 225 SUPERFAMILY SSF51735 83 207 1.97E-29 T 28-03-2018 IPR016040 NAD(P)-binding domain ALX04_RS14480 a3f85e26ed20bbf5bf58d4b7f2d97617 225 Hamap MF_01131 Redox-sensing transcriptional repressor Rex [rex]. 1 209 40.098 T 28-03-2018 IPR022876 Redox-sensing transcriptional repressor Rex GO:0005737|GO:0045892|GO:0051775 ALX04_RS14480 a3f85e26ed20bbf5bf58d4b7f2d97617 225 Gene3D G3DSA:3.40.50.720 71 187 3.5E-18 T 28-03-2018 ALX04_RS14480 a3f85e26ed20bbf5bf58d4b7f2d97617 225 SUPERFAMILY SSF46785 7 78 1.12E-23 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS14480 a3f85e26ed20bbf5bf58d4b7f2d97617 225 Pfam PF02629 CoA binding domain 83 178 5.1E-26 T 28-03-2018 IPR003781 CoA-binding GO:0048037 ALX04_RS14480 a3f85e26ed20bbf5bf58d4b7f2d97617 225 SMART SM00881 79 180 5.9E-18 T 28-03-2018 IPR003781 CoA-binding GO:0048037 ALX04_RS14480 a3f85e26ed20bbf5bf58d4b7f2d97617 225 Gene3D G3DSA:1.10.10.10 4 70 1.3E-27 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS02820 45d3cb9d3c5ed05d0fac71b172db140e 298 Gene3D G3DSA:1.10.40.50 228 296 6.0E-22 T 28-03-2018 ALX04_RS02820 45d3cb9d3c5ed05d0fac71b172db140e 298 Pfam PF03193 RsgA GTPase 59 226 2.8E-52 T 28-03-2018 IPR010914 RsgA GTPase domain GO:0003924|GO:0005525 ALX04_RS02820 45d3cb9d3c5ed05d0fac71b172db140e 298 SUPERFAMILY SSF52540 65 292 2.67E-48 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase ALX04_RS02820 45d3cb9d3c5ed05d0fac71b172db140e 298 Hamap MF_01820 Putative ribosome biogenesis GTPase RsgA [rsgA]. 2 291 36.039 T 28-03-2018 IPR004881 Ribosome biogenesis GTPase RsgA GO:0003924|GO:0005525 ALX04_RS02820 45d3cb9d3c5ed05d0fac71b172db140e 298 Gene3D G3DSA:2.40.50.140 1 61 5.3E-17 T 28-03-2018 ALX04_RS02820 45d3cb9d3c5ed05d0fac71b172db140e 298 Pfam PF16745 RsgA N-terminal domain 4 56 1.6E-21 T 28-03-2018 IPR031944 Ribosome biogenesis GTPase RsgA, N-terminal ALX04_RS02820 45d3cb9d3c5ed05d0fac71b172db140e 298 TIGRFAM TIGR00157 TIGR00157: ribosome small subunit-dependent GTPase A 39 283 2.0E-65 T 28-03-2018 IPR004881 Ribosome biogenesis GTPase RsgA GO:0003924|GO:0005525 ALX04_RS02820 45d3cb9d3c5ed05d0fac71b172db140e 298 SUPERFAMILY SSF50249 3 63 5.57E-13 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold ALX04_RS02820 45d3cb9d3c5ed05d0fac71b172db140e 298 Gene3D G3DSA:3.40.50.300 62 226 5.7E-20 T 28-03-2018 ALX04_RS15120 7c26fcc06ba61efce437518a4f31ec39 396 SUPERFAMILY SSF53383 9 389 8.74E-106 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase ALX04_RS15120 7c26fcc06ba61efce437518a4f31ec39 396 Pfam PF00155 Aminotransferase class I and II 37 385 3.6E-67 T 28-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 ALX04_RS15120 7c26fcc06ba61efce437518a4f31ec39 396 Gene3D G3DSA:3.90.1150.10 303 393 5.2E-25 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 ALX04_RS15120 7c26fcc06ba61efce437518a4f31ec39 396 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 237 250 - T 28-03-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 ALX04_RS15120 7c26fcc06ba61efce437518a4f31ec39 396 PRINTS PR00753 1-aminocyclopropane-1-carboxylate synthase signature 204 227 7.7E-11 T 28-03-2018 ALX04_RS15120 7c26fcc06ba61efce437518a4f31ec39 396 PRINTS PR00753 1-aminocyclopropane-1-carboxylate synthase signature 168 192 7.7E-11 T 28-03-2018 ALX04_RS15120 7c26fcc06ba61efce437518a4f31ec39 396 PRINTS PR00753 1-aminocyclopropane-1-carboxylate synthase signature 98 118 7.7E-11 T 28-03-2018 ALX04_RS15120 7c26fcc06ba61efce437518a4f31ec39 396 PRINTS PR00753 1-aminocyclopropane-1-carboxylate synthase signature 120 141 7.7E-11 T 28-03-2018 ALX04_RS15120 7c26fcc06ba61efce437518a4f31ec39 396 Gene3D G3DSA:3.40.640.10 50 302 6.8E-57 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 ALX04_RS04250 3d038d1be35dbc1810435a461f4fabd4 256 Pfam PF01061 ABC-2 type transporter 16 210 3.6E-10 T 28-03-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 ALX04_RS05510 819295c27d83accdc7ac1c8b1fcacebf 427 PRINTS PR00423 Cell division protein FtsZ signature 127 148 6.0E-52 T 28-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 ALX04_RS05510 819295c27d83accdc7ac1c8b1fcacebf 427 PRINTS PR00423 Cell division protein FtsZ signature 213 234 6.0E-52 T 28-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 ALX04_RS05510 819295c27d83accdc7ac1c8b1fcacebf 427 PRINTS PR00423 Cell division protein FtsZ signature 99 119 6.0E-52 T 28-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 ALX04_RS05510 819295c27d83accdc7ac1c8b1fcacebf 427 PRINTS PR00423 Cell division protein FtsZ signature 190 212 6.0E-52 T 28-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 ALX04_RS05510 819295c27d83accdc7ac1c8b1fcacebf 427 Hamap MF_00909 Cell division protein FtsZ [ftsZ]. 10 367 38.757 T 28-03-2018 IPR000158 Cell division protein FtsZ GO:0005525 ALX04_RS05510 819295c27d83accdc7ac1c8b1fcacebf 427 SUPERFAMILY SSF55307 205 320 3.66E-44 T 28-03-2018 IPR008280 Tubulin/FtsZ, C-terminal Reactome: R-HSA-380320 ALX04_RS05510 819295c27d83accdc7ac1c8b1fcacebf 427 SUPERFAMILY SSF52490 13 209 7.2E-69 T 28-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 ALX04_RS05510 819295c27d83accdc7ac1c8b1fcacebf 427 SMART SM00865 208 325 9.3E-57 T 28-03-2018 IPR018316 Tubulin/FtsZ, 2-layer sandwich domain Reactome: R-HSA-1445148|Reactome: R-HSA-190840|Reactome: R-HSA-190861|Reactome: R-HSA-2132295|Reactome: R-HSA-2467813|Reactome: R-HSA-2500257|Reactome: R-HSA-3371497|Reactome: R-HSA-380320|Reactome: R-HSA-437239|Reactome: R-HSA-5617833|Reactome: R-HSA-5626467|Reactome: R-HSA-5663220|Reactome: R-HSA-6807878|Reactome: R-HSA-6811434|Reactome: R-HSA-6811436|Reactome: R-HSA-68877|Reactome: R-HSA-8852276|Reactome: R-HSA-8955332|Reactome: R-HSA-983189 ALX04_RS05510 819295c27d83accdc7ac1c8b1fcacebf 427 Gene3D G3DSA:3.40.50.1440 9 215 5.6E-46 T 28-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 ALX04_RS05510 819295c27d83accdc7ac1c8b1fcacebf 427 Pfam PF12327 FtsZ family, C-terminal domain 223 317 4.2E-34 T 28-03-2018 IPR024757 Cell division protein FtsZ, C-terminal ALX04_RS05510 819295c27d83accdc7ac1c8b1fcacebf 427 Gene3D G3DSA:3.30.1330.20 216 324 1.9E-47 T 28-03-2018 IPR018316 Tubulin/FtsZ, 2-layer sandwich domain Reactome: R-HSA-1445148|Reactome: R-HSA-190840|Reactome: R-HSA-190861|Reactome: R-HSA-2132295|Reactome: R-HSA-2467813|Reactome: R-HSA-2500257|Reactome: R-HSA-3371497|Reactome: R-HSA-380320|Reactome: R-HSA-437239|Reactome: R-HSA-5617833|Reactome: R-HSA-5626467|Reactome: R-HSA-5663220|Reactome: R-HSA-6807878|Reactome: R-HSA-6811434|Reactome: R-HSA-6811436|Reactome: R-HSA-68877|Reactome: R-HSA-8852276|Reactome: R-HSA-8955332|Reactome: R-HSA-983189 ALX04_RS05510 819295c27d83accdc7ac1c8b1fcacebf 427 ProSitePatterns PS01134 FtsZ protein signature 1. 45 79 - T 28-03-2018 IPR020805 Cell division protein FtsZ, conserved site GO:0005525|GO:0005737 ALX04_RS05510 819295c27d83accdc7ac1c8b1fcacebf 427 TIGRFAM TIGR00065 ftsZ: cell division protein FtsZ 7 332 1.5E-132 T 28-03-2018 IPR000158 Cell division protein FtsZ GO:0005525 ALX04_RS05510 819295c27d83accdc7ac1c8b1fcacebf 427 Pfam PF00091 Tubulin/FtsZ family, GTPase domain 14 174 3.9E-40 T 28-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 ALX04_RS05510 819295c27d83accdc7ac1c8b1fcacebf 427 SMART SM00864 14 206 1.2E-113 T 28-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 ALX04_RS09130 cd3872a6afbd5f50d7aa8c33d8396002 161 Pfam PF04138 GtrA-like protein 43 158 6.9E-23 T 28-03-2018 IPR007267 GtrA-like protein GO:0000271|GO:0006810|GO:0016021 ALX04_RS02865 172f5e76ca203cfa09c26e9451fe931b 231 SMART SM00535 21 156 7.2E-53 T 28-03-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 ALX04_RS02865 172f5e76ca203cfa09c26e9451fe931b 231 Pfam PF00035 Double-stranded RNA binding motif 162 228 4.3E-16 T 28-03-2018 IPR014720 Double-stranded RNA-binding domain ALX04_RS02865 172f5e76ca203cfa09c26e9451fe931b 231 SUPERFAMILY SSF54768 155 229 1.89E-20 T 28-03-2018 ALX04_RS02865 172f5e76ca203cfa09c26e9451fe931b 231 Gene3D G3DSA:1.10.1520.10 6 153 9.4E-45 T 28-03-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 ALX04_RS02865 172f5e76ca203cfa09c26e9451fe931b 231 SUPERFAMILY SSF69065 5 164 8.37E-51 T 28-03-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 ALX04_RS02865 172f5e76ca203cfa09c26e9451fe931b 231 Pfam PF14622 Ribonuclease-III-like 19 151 1.0E-32 T 28-03-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 ALX04_RS02865 172f5e76ca203cfa09c26e9451fe931b 231 SMART SM00358 162 229 1.8E-18 T 28-03-2018 IPR014720 Double-stranded RNA-binding domain ALX04_RS02865 172f5e76ca203cfa09c26e9451fe931b 231 TIGRFAM TIGR02191 RNaseIII: ribonuclease III 10 228 2.8E-73 T 28-03-2018 IPR011907 Ribonuclease III GO:0003723|GO:0004525|GO:0016075 Reactome: R-HSA-203927 ALX04_RS02865 172f5e76ca203cfa09c26e9451fe931b 231 Gene3D G3DSA:3.30.160.20 154 231 2.8E-19 T 28-03-2018 ALX04_RS02865 172f5e76ca203cfa09c26e9451fe931b 231 Hamap MF_00104 Ribonuclease 3 [rnc]. 9 225 29.126 T 28-03-2018 IPR011907 Ribonuclease III GO:0003723|GO:0004525|GO:0016075 Reactome: R-HSA-203927 ALX04_RS12290 fbda330282a266179530581c7cb379f5 122 SUPERFAMILY SSF53062 2 118 3.66E-29 T 28-03-2018 IPR004701 Phosphotransferase system, mannose-type IIA component GO:0009401|GO:0016021 ALX04_RS12290 fbda330282a266179530581c7cb379f5 122 Pfam PF03610 PTS system fructose IIA component 4 104 2.7E-22 T 28-03-2018 IPR004701 Phosphotransferase system, mannose-type IIA component GO:0009401|GO:0016021 ALX04_RS12290 fbda330282a266179530581c7cb379f5 122 TIGRFAM TIGR02364 dha_pts: dihydroxyacetone kinase, phosphotransfer subunit 4 113 1.2E-34 T 28-03-2018 IPR012844 Dihydroxyacetone kinase phosphotransferase subunit, N-terminal domain ALX04_RS12290 fbda330282a266179530581c7cb379f5 122 Gene3D G3DSA:3.40.50.510 1 118 9.2E-25 T 28-03-2018 IPR004701 Phosphotransferase system, mannose-type IIA component GO:0009401|GO:0016021 ALX04_RS14510 57911cd43c73e44a9b64d78b4389e9e9 300 TIGRFAM TIGR02136 ptsS_2: phosphate binding protein 1 283 1.1E-82 T 28-03-2018 IPR011862 Phosphate binding protein GO:0006810 ALX04_RS14510 57911cd43c73e44a9b64d78b4389e9e9 300 Gene3D G3DSA:3.40.190.10 176 299 7.6E-15 T 28-03-2018 ALX04_RS14510 57911cd43c73e44a9b64d78b4389e9e9 300 Gene3D G3DSA:3.40.190.10 39 175 2.4E-30 T 28-03-2018 ALX04_RS14510 57911cd43c73e44a9b64d78b4389e9e9 300 SUPERFAMILY SSF53850 44 291 1.29E-74 T 28-03-2018 ALX04_RS14510 57911cd43c73e44a9b64d78b4389e9e9 300 Pfam PF12849 PBP superfamily domain 35 268 1.7E-40 T 28-03-2018 IPR024370 PBP domain ALX04_RS03590 bd0d8f35d0a879683464a9b13acb94c5 144 Gene3D G3DSA:3.40.630.30 5 143 9.6E-30 T 28-03-2018 ALX04_RS03590 bd0d8f35d0a879683464a9b13acb94c5 144 Pfam PF13673 Acetyltransferase (GNAT) domain 64 143 2.2E-11 T 28-03-2018 IPR000182 GNAT domain GO:0008080 ALX04_RS03590 bd0d8f35d0a879683464a9b13acb94c5 144 SUPERFAMILY SSF55729 3 143 4.43E-32 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase ALX04_RS03835 464b852f99b33c2b17093f2256989686 491 Pfam PF07690 Major Facilitator Superfamily 13 401 7.8E-45 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 ALX04_RS03835 464b852f99b33c2b17093f2256989686 491 Gene3D G3DSA:1.20.1250.20 246 491 1.9E-17 T 28-03-2018 ALX04_RS03835 464b852f99b33c2b17093f2256989686 491 SUPERFAMILY SSF103473 4 195 4.71E-59 T 28-03-2018 IPR020846 Major facilitator superfamily domain ALX04_RS03835 464b852f99b33c2b17093f2256989686 491 SUPERFAMILY SSF103473 457 487 4.71E-59 T 28-03-2018 IPR020846 Major facilitator superfamily domain ALX04_RS03835 464b852f99b33c2b17093f2256989686 491 SUPERFAMILY SSF103473 242 413 4.71E-59 T 28-03-2018 IPR020846 Major facilitator superfamily domain ALX04_RS03835 464b852f99b33c2b17093f2256989686 491 Gene3D G3DSA:1.20.1250.20 10 197 4.8E-34 T 28-03-2018 ALX04_RS07075 bc7a2d5953c1404c485e6afdd1862526 450 Pfam PF00342 Phosphoglucose isomerase 76 425 6.5E-18 T 28-03-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 ALX04_RS07075 bc7a2d5953c1404c485e6afdd1862526 450 ProSitePatterns PS00765 Phosphoglucose isomerase signature 1. 202 215 - T 28-03-2018 IPR018189 Phosphoglucose isomerase, conserved site GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 ALX04_RS07075 bc7a2d5953c1404c485e6afdd1862526 450 SUPERFAMILY SSF53697 4 446 1.39E-133 T 28-03-2018 ALX04_RS07075 bc7a2d5953c1404c485e6afdd1862526 450 Hamap MF_00473 Glucose-6-phosphate isomerase [pgi]. 1 435 23.961 T 28-03-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 ALX04_RS07075 bc7a2d5953c1404c485e6afdd1862526 450 ProSitePatterns PS00174 Phosphoglucose isomerase signature 2. 408 425 - T 28-03-2018 IPR018189 Phosphoglucose isomerase, conserved site GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 ALX04_RS07075 bc7a2d5953c1404c485e6afdd1862526 450 Gene3D G3DSA:3.40.50.10490 53 224 9.3E-51 T 28-03-2018 ALX04_RS07075 bc7a2d5953c1404c485e6afdd1862526 450 Gene3D G3DSA:3.40.50.10490 1 52 3.0E-9 T 28-03-2018 ALX04_RS07075 bc7a2d5953c1404c485e6afdd1862526 450 Gene3D G3DSA:3.40.50.10490 225 417 1.0E-55 T 28-03-2018 ALX04_RS07075 bc7a2d5953c1404c485e6afdd1862526 450 PRINTS PR00662 Glucose-6-phosphate isomerase signature 273 294 2.3E-23 T 28-03-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 ALX04_RS07075 bc7a2d5953c1404c485e6afdd1862526 450 PRINTS PR00662 Glucose-6-phosphate isomerase signature 394 408 2.3E-23 T 28-03-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 ALX04_RS07075 bc7a2d5953c1404c485e6afdd1862526 450 PRINTS PR00662 Glucose-6-phosphate isomerase signature 76 95 2.3E-23 T 28-03-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 ALX04_RS07075 bc7a2d5953c1404c485e6afdd1862526 450 PRINTS PR00662 Glucose-6-phosphate isomerase signature 408 421 2.3E-23 T 28-03-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 ALX04_RS07075 bc7a2d5953c1404c485e6afdd1862526 450 PRINTS PR00662 Glucose-6-phosphate isomerase signature 376 394 2.3E-23 T 28-03-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 ALX04_RS07075 bc7a2d5953c1404c485e6afdd1862526 450 PRINTS PR00662 Glucose-6-phosphate isomerase signature 198 216 2.3E-23 T 28-03-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 ALX04_RS08895 10d549f7ff4fffd575f6bcadb2a3539f 740 Gene3D G3DSA:3.20.70.20 128 693 3.7E-194 T 28-03-2018 ALX04_RS08895 10d549f7ff4fffd575f6bcadb2a3539f 740 TIGRFAM TIGR02487 NrdD: anaerobic ribonucleoside-triphosphate reductase 123 710 2.0E-171 T 28-03-2018 IPR012833 Ribonucleoside-triphosphate reductase, anaerobic GO:0006260|GO:0008998|GO:0016491|GO:0055114 KEGG: 00230+1.17.4.2|KEGG: 00240+1.17.4.2 ALX04_RS08895 10d549f7ff4fffd575f6bcadb2a3539f 740 ProSitePatterns PS00850 Glycine radical domain signature. 682 690 - T 28-03-2018 IPR019777 Formate C-acetyltransferase glycine radical, conserved site ALX04_RS08895 10d549f7ff4fffd575f6bcadb2a3539f 740 Pfam PF13597 Anaerobic ribonucleoside-triphosphate reductase 123 709 1.5E-171 T 28-03-2018 IPR012833 Ribonucleoside-triphosphate reductase, anaerobic GO:0006260|GO:0008998|GO:0016491|GO:0055114 KEGG: 00230+1.17.4.2|KEGG: 00240+1.17.4.2 ALX04_RS08895 10d549f7ff4fffd575f6bcadb2a3539f 740 SUPERFAMILY SSF51998 128 693 1.13E-190 T 28-03-2018 ALX04_RS15875 bec8811ddf42cbed5d31f3a7a71d108b 305 SUPERFAMILY SSF53850 198 304 3.34E-23 T 28-03-2018 ALX04_RS15875 bec8811ddf42cbed5d31f3a7a71d108b 305 Pfam PF04069 Substrate binding domain of ABC-type glycine betaine transport system 39 183 1.6E-34 T 28-03-2018 IPR007210 ABC-type glycine betaine transport system, substrate-binding domain GO:0005215|GO:0006810 ALX04_RS15875 bec8811ddf42cbed5d31f3a7a71d108b 305 Pfam PF04069 Substrate binding domain of ABC-type glycine betaine transport system 201 304 1.2E-16 T 28-03-2018 IPR007210 ABC-type glycine betaine transport system, substrate-binding domain GO:0005215|GO:0006810 ALX04_RS15875 bec8811ddf42cbed5d31f3a7a71d108b 305 SUPERFAMILY SSF53850 42 195 1.63E-44 T 28-03-2018 ALX04_RS15875 bec8811ddf42cbed5d31f3a7a71d108b 305 Gene3D G3DSA:3.40.190.10 201 287 6.7E-9 T 28-03-2018 ALX04_RS15875 bec8811ddf42cbed5d31f3a7a71d108b 305 Gene3D G3DSA:3.40.190.10 37 200 1.1E-31 T 28-03-2018 ALX04_RS15875 bec8811ddf42cbed5d31f3a7a71d108b 305 Gene3D G3DSA:3.40.190.100 288 305 0.21 T 28-03-2018 ALX04_RS11915 bb93267b3c8ea29ac76808c761afc1b7 107 Pfam PF01022 Bacterial regulatory protein, arsR family 21 66 1.7E-12 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 ALX04_RS11915 bb93267b3c8ea29ac76808c761afc1b7 107 Gene3D G3DSA:1.10.10.10 3 105 1.2E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS11915 bb93267b3c8ea29ac76808c761afc1b7 107 SMART SM00418 14 93 7.1E-14 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 ALX04_RS11915 bb93267b3c8ea29ac76808c761afc1b7 107 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 49 64 7.3E-11 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 ALX04_RS11915 bb93267b3c8ea29ac76808c761afc1b7 107 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 16 31 7.3E-11 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 ALX04_RS11915 bb93267b3c8ea29ac76808c761afc1b7 107 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 64 79 7.3E-11 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 ALX04_RS11915 bb93267b3c8ea29ac76808c761afc1b7 107 SUPERFAMILY SSF46785 13 87 1.22E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS02350 83568d3feacb46e09d0b0cbae9892ad8 118 Gene3D G3DSA:1.10.1900.20 55 116 2.3E-28 T 28-03-2018 IPR035566 Ribosomal protein L20 C-terminal domain Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 ALX04_RS02350 83568d3feacb46e09d0b0cbae9892ad8 118 TIGRFAM TIGR01032 rplT_bact: ribosomal protein bL20 1 114 1.1E-48 T 28-03-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 ALX04_RS02350 83568d3feacb46e09d0b0cbae9892ad8 118 ProSitePatterns PS00937 Ribosomal protein L20 signature. 54 70 - T 28-03-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 ALX04_RS02350 83568d3feacb46e09d0b0cbae9892ad8 118 Hamap MF_00382 50S ribosomal protein L20 [rplT]. 2 115 28.975 T 28-03-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 ALX04_RS02350 83568d3feacb46e09d0b0cbae9892ad8 118 SUPERFAMILY SSF74731 3 117 1.96E-47 T 28-03-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 ALX04_RS02350 83568d3feacb46e09d0b0cbae9892ad8 118 ProDom PD002389 RIBOSOMAL RRNA-BINDING RNA-BINDING RIBONUCLEOPROTEIN L20 50S L20 CHLOROPLAST BACTERIAL ORGANELLE 23 46 3.0E-7 T 28-03-2018 ALX04_RS02350 83568d3feacb46e09d0b0cbae9892ad8 118 PRINTS PR00062 Ribosomal protein L20 signature 42 71 1.0E-39 T 28-03-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 ALX04_RS02350 83568d3feacb46e09d0b0cbae9892ad8 118 PRINTS PR00062 Ribosomal protein L20 signature 12 41 1.0E-39 T 28-03-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 ALX04_RS02350 83568d3feacb46e09d0b0cbae9892ad8 118 PRINTS PR00062 Ribosomal protein L20 signature 75 101 1.0E-39 T 28-03-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 ALX04_RS02350 83568d3feacb46e09d0b0cbae9892ad8 118 Pfam PF00453 Ribosomal protein L20 3 109 1.6E-45 T 28-03-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 ALX04_RS15665 fdcd703ee86f4c7bc2acba935aa2cc08 389 Pfam PF03432 Relaxase/Mobilisation nuclease domain 9 246 9.4E-54 T 28-03-2018 IPR005094 Endonuclease relaxase, MobA/VirD2 ALX04_RS14400 453d7f4831d6e646c975000cc8062b2d 115 Pfam PF06156 Initiation control protein YabA 2 106 4.7E-34 T 28-03-2018 IPR010377 Initiation control protein YabA GO:0006260 ALX04_RS14400 453d7f4831d6e646c975000cc8062b2d 115 Gene3D G3DSA:1.20.1270.60 2 88 4.6E-4 T 28-03-2018 ALX04_RS14400 453d7f4831d6e646c975000cc8062b2d 115 Hamap MF_01159 Initiation-control protein YabA. 1 110 24.515 T 28-03-2018 IPR010377 Initiation control protein YabA GO:0006260 ALX04_RS14400 453d7f4831d6e646c975000cc8062b2d 115 PIRSF PIRSF021439 1 111 6.5E-41 T 28-03-2018 IPR010377 Initiation control protein YabA GO:0006260 ALX04_RS04845 641f4323e5b9de1087304f5e86128b64 231 Pfam PF00574 Clp protease 39 171 1.1E-26 T 28-03-2018 IPR023562 Clp protease proteolytic subunit /Translocation-enhancing protein TepA ALX04_RS04845 641f4323e5b9de1087304f5e86128b64 231 Gene3D G3DSA:3.90.226.10 25 174 2.7E-26 T 28-03-2018 ALX04_RS04845 641f4323e5b9de1087304f5e86128b64 231 SUPERFAMILY SSF52096 35 176 1.31E-37 T 28-03-2018 IPR029045 ClpP/crotonase-like domain ALX04_RS10560 81433d385b51b84f54fa9788d6e44a07 302 SUPERFAMILY SSF103481 200 294 1.16E-9 T 28-03-2018 ALX04_RS10560 81433d385b51b84f54fa9788d6e44a07 302 SUPERFAMILY SSF103481 52 150 1.31E-8 T 28-03-2018 ALX04_RS10560 81433d385b51b84f54fa9788d6e44a07 302 Pfam PF00892 EamA-like transporter family 7 147 7.1E-18 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 ALX04_RS10560 81433d385b51b84f54fa9788d6e44a07 302 Pfam PF00892 EamA-like transporter family 162 292 2.1E-19 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 ALX04_RS10650 bb8f2ef3e6682975062373321bb86e19 157 Pfam PF05014 Nucleoside 2-deoxyribosyltransferase 4 115 1.4E-20 T 28-03-2018 IPR007710 Nucleoside 2-deoxyribosyltransferase GO:0009159|GO:0050144|GO:0070694 Reactome: R-HSA-74259 ALX04_RS10650 bb8f2ef3e6682975062373321bb86e19 157 Gene3D G3DSA:3.40.50.450 1 157 1.4E-33 T 28-03-2018 ALX04_RS10650 bb8f2ef3e6682975062373321bb86e19 157 SUPERFAMILY SSF52309 1 154 2.11E-43 T 28-03-2018 ALX04_RS14250 eeca9f343ad28b07fe18e2c82ff299a2 470 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 225 246 3.5E-29 T 28-03-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 ALX04_RS14250 eeca9f343ad28b07fe18e2c82ff299a2 470 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 25 36 3.5E-29 T 28-03-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 ALX04_RS14250 eeca9f343ad28b07fe18e2c82ff299a2 470 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 194 212 3.5E-29 T 28-03-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 ALX04_RS14250 eeca9f343ad28b07fe18e2c82ff299a2 470 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 61 70 3.5E-29 T 28-03-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 ALX04_RS14250 eeca9f343ad28b07fe18e2c82ff299a2 470 SMART SM00840 356 420 4.2E-14 T 28-03-2018 IPR015273 Cysteinyl-tRNA synthetase, class Ia, DALR GO:0000166|GO:0004817|GO:0005524|GO:0005737|GO:0006423 KEGG: 00970+6.1.1.16 ALX04_RS14250 eeca9f343ad28b07fe18e2c82ff299a2 470 Hamap MF_00041 Cysteine--tRNA ligase [cysS]. 2 470 38.19 T 28-03-2018 IPR015803 Cysteine-tRNA ligase GO:0004817|GO:0005524|GO:0006423 KEGG: 00970+6.1.1.16 ALX04_RS14250 eeca9f343ad28b07fe18e2c82ff299a2 470 Gene3D G3DSA:1.20.120.640 311 410 2.8E-16 T 28-03-2018 ALX04_RS14250 eeca9f343ad28b07fe18e2c82ff299a2 470 Pfam PF01406 tRNA synthetases class I (C) catalytic domain 15 318 1.6E-130 T 28-03-2018 IPR032678 tRNA synthetases class I, catalytic domain KEGG: 00970+6.1.1.16 ALX04_RS14250 eeca9f343ad28b07fe18e2c82ff299a2 470 SUPERFAMILY SSF47323 321 468 1.37E-32 T 28-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 ALX04_RS14250 eeca9f343ad28b07fe18e2c82ff299a2 470 Gene3D G3DSA:3.40.50.620 1 310 3.3E-90 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold ALX04_RS14250 eeca9f343ad28b07fe18e2c82ff299a2 470 SUPERFAMILY SSF52374 2 319 7.93E-97 T 28-03-2018 ALX04_RS14250 eeca9f343ad28b07fe18e2c82ff299a2 470 TIGRFAM TIGR00435 cysS: cysteine--tRNA ligase 2 469 2.4E-175 T 28-03-2018 IPR015803 Cysteine-tRNA ligase GO:0004817|GO:0005524|GO:0006423 KEGG: 00970+6.1.1.16 ALX04_RS14250 eeca9f343ad28b07fe18e2c82ff299a2 470 Pfam PF09190 DALR domain 356 419 3.3E-13 T 28-03-2018 IPR015273 Cysteinyl-tRNA synthetase, class Ia, DALR GO:0000166|GO:0004817|GO:0005524|GO:0005737|GO:0006423 KEGG: 00970+6.1.1.16 ALX04_RS15430 65aaead5cbcbb82f6fc3fd5571ee22b4 184 Gene3D G3DSA:1.20.5.40 107 133 4.9E-14 T 28-03-2018 ALX04_RS15430 65aaead5cbcbb82f6fc3fd5571ee22b4 184 SUPERFAMILY SSF46689 140 181 3.11E-7 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 ALX04_RS15430 65aaead5cbcbb82f6fc3fd5571ee22b4 184 ProSitePatterns PS00397 Site-specific recombinases active site. 5 13 - T 28-03-2018 IPR006118 Recombinase, conserved site GO:0000150|GO:0006310 ALX04_RS15430 65aaead5cbcbb82f6fc3fd5571ee22b4 184 Pfam PF00239 Resolvase, N terminal domain 3 132 7.8E-39 T 28-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 ALX04_RS15430 65aaead5cbcbb82f6fc3fd5571ee22b4 184 Gene3D G3DSA:3.40.50.1390 2 106 1.6E-31 T 28-03-2018 ALX04_RS15430 65aaead5cbcbb82f6fc3fd5571ee22b4 184 SUPERFAMILY SSF53041 1 132 1.96E-40 T 28-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 ALX04_RS15430 65aaead5cbcbb82f6fc3fd5571ee22b4 184 SMART SM00857 2 142 3.9E-49 T 28-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 ALX04_RS15430 65aaead5cbcbb82f6fc3fd5571ee22b4 184 Gene3D G3DSA:1.10.10.60 139 182 4.9E-9 T 28-03-2018 ALX04_RS13475 6128fa4600bacbfc685ba7f7cbbe15a8 298 Gene3D G3DSA:3.30.420.40 116 297 1.0E-42 T 28-03-2018 ALX04_RS13475 6128fa4600bacbfc685ba7f7cbbe15a8 298 Gene3D G3DSA:3.30.420.40 2 115 1.1E-27 T 28-03-2018 ALX04_RS13475 6128fa4600bacbfc685ba7f7cbbe15a8 298 SUPERFAMILY SSF53067 1 295 5.99E-56 T 28-03-2018 ALX04_RS13475 6128fa4600bacbfc685ba7f7cbbe15a8 298 Pfam PF00480 ROK family 4 292 6.3E-52 T 28-03-2018 IPR000600 ROK family Reactome: R-HSA-4085001 ALX04_RS14330 a24c2c337a8b7fb16503e683e57df427 191 SUPERFAMILY SSF102405 3 180 1.04E-57 T 28-03-2018 ALX04_RS14330 a24c2c337a8b7fb16503e683e57df427 191 TIGRFAM TIGR00730 TIGR00730: TIGR00730 family protein 5 176 8.7E-55 T 28-03-2018 IPR005269 Cytokinin riboside 5'-monophosphate phosphoribohydrolase LOG ALX04_RS14330 a24c2c337a8b7fb16503e683e57df427 191 Pfam PF03641 Possible lysine decarboxylase 48 175 1.4E-39 T 28-03-2018 IPR031100 LOG family ALX04_RS14330 a24c2c337a8b7fb16503e683e57df427 191 Gene3D G3DSA:3.40.50.450 1 186 6.4E-52 T 28-03-2018 ALX04_RS15140 487d19deba04aa7dc588eeb4318bd4d0 246 ProSitePatterns PS00211 ABC transporters family signature. 139 153 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 ALX04_RS15140 487d19deba04aa7dc588eeb4318bd4d0 246 Pfam PF00005 ABC transporter 19 167 1.7E-36 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 ALX04_RS15140 487d19deba04aa7dc588eeb4318bd4d0 246 SUPERFAMILY SSF52540 3 230 1.21E-77 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase ALX04_RS15140 487d19deba04aa7dc588eeb4318bd4d0 246 SMART SM00382 28 216 2.6E-15 T 28-03-2018 IPR003593 AAA+ ATPase domain ALX04_RS15140 487d19deba04aa7dc588eeb4318bd4d0 246 PIRSF PIRSF039085 1 245 1.4E-100 T 28-03-2018 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 ALX04_RS15140 487d19deba04aa7dc588eeb4318bd4d0 246 Gene3D G3DSA:3.40.50.300 1 244 9.3E-72 T 28-03-2018 ALX04_RS03550 9a0f024eb0cb5e55c9ca02db9beb9c66 123 Gene3D G3DSA:3.40.1440.10 18 121 7.3E-12 T 28-03-2018 IPR000305 GIY-YIG nuclease superfamily ALX04_RS03550 9a0f024eb0cb5e55c9ca02db9beb9c66 123 SUPERFAMILY SSF82771 19 120 1.14E-13 T 28-03-2018 IPR000305 GIY-YIG nuclease superfamily ALX04_RS01855 3a2b2d7ec86ca87bb6198616a75fd067 119 ProDom PD067392 MEMBRANE UPF0344 TRANSMEMBRANE MW0851 BCE1257 SIMILAR YISL SAR0931 BCE33L1051 BT9727_1053 6 87 1.0E-4 T 28-03-2018 IPR010899 Protein of unknown function UPF0344 ALX04_RS01855 3a2b2d7ec86ca87bb6198616a75fd067 119 Pfam PF07457 Protein of unknown function (DUF1516) 5 107 3.2E-24 T 28-03-2018 IPR010899 Protein of unknown function UPF0344 ALX04_RS01855 3a2b2d7ec86ca87bb6198616a75fd067 119 Hamap MF_01536 UPF0344 protein . 2 119 13.393 T 28-03-2018 IPR010899 Protein of unknown function UPF0344 ALX04_RS06360 ca0005effb406ba7c2407c479b43adeb 230 SUPERFAMILY SSF161098 17 215 1.23E-45 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 ALX04_RS06360 ca0005effb406ba7c2407c479b43adeb 230 Gene3D G3DSA:1.10.3720.10 15 228 3.2E-40 T 28-03-2018 ALX04_RS06360 ca0005effb406ba7c2407c479b43adeb 230 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 59 229 5.0E-26 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 ALX04_RS10280 da2d4db3697fdbcc5df93867d6cff3c7 295 Pfam PF01545 Cation efflux family 16 201 5.8E-42 T 28-03-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 ALX04_RS10280 da2d4db3697fdbcc5df93867d6cff3c7 295 SUPERFAMILY SSF161111 9 205 2.09E-53 T 28-03-2018 ALX04_RS10280 da2d4db3697fdbcc5df93867d6cff3c7 295 TIGRFAM TIGR01297 CDF: cation diffusion facilitator family transporter 12 282 7.1E-73 T 28-03-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 ALX04_RS10280 da2d4db3697fdbcc5df93867d6cff3c7 295 Gene3D G3DSA:3.30.70.1350 207 284 2.4E-9 T 28-03-2018 IPR027470 Cation efflux protein, cytoplasmic domain ALX04_RS10280 da2d4db3697fdbcc5df93867d6cff3c7 295 SUPERFAMILY SSF160240 210 282 4.05E-8 T 28-03-2018 ALX04_RS10280 da2d4db3697fdbcc5df93867d6cff3c7 295 Gene3D G3DSA:1.20.1510.10 10 203 1.0E-50 T 28-03-2018 ALX04_RS07550 576ce02fa5c6e3a922714e7d6fb456f7 585 ProSitePatterns PS00187 Thiamine pyrophosphate enzymes signature. 423 442 - T 28-03-2018 IPR000399 TPP-binding enzyme, conserved site GO:0000287|GO:0030976 ALX04_RS07550 576ce02fa5c6e3a922714e7d6fb456f7 585 Gene3D G3DSA:3.40.50.970 350 546 5.7E-34 T 28-03-2018 ALX04_RS07550 576ce02fa5c6e3a922714e7d6fb456f7 585 SUPERFAMILY SSF52467 189 355 3.07E-33 T 28-03-2018 IPR029035 DHS-like NAD/FAD-binding domain ALX04_RS07550 576ce02fa5c6e3a922714e7d6fb456f7 585 Gene3D G3DSA:3.40.50.970 1 187 1.1E-35 T 28-03-2018 ALX04_RS07550 576ce02fa5c6e3a922714e7d6fb456f7 585 TIGRFAM TIGR02720 pyruv_oxi_spxB: pyruvate oxidase 7 581 0.0 T 28-03-2018 IPR014092 Pyruvate oxidase GO:0047112|GO:0055114 KEGG: 00620+1.2.3.3 ALX04_RS07550 576ce02fa5c6e3a922714e7d6fb456f7 585 SUPERFAMILY SSF52518 362 581 1.69E-52 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold ALX04_RS07550 576ce02fa5c6e3a922714e7d6fb456f7 585 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 386 535 1.6E-33 T 28-03-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 ALX04_RS07550 576ce02fa5c6e3a922714e7d6fb456f7 585 SUPERFAMILY SSF52518 7 174 1.82E-38 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold ALX04_RS07550 576ce02fa5c6e3a922714e7d6fb456f7 585 Gene3D G3DSA:3.40.50.1220 188 349 5.3E-28 T 28-03-2018 IPR029035 DHS-like NAD/FAD-binding domain ALX04_RS07550 576ce02fa5c6e3a922714e7d6fb456f7 585 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 8 171 5.8E-39 T 28-03-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 ALX04_RS07550 576ce02fa5c6e3a922714e7d6fb456f7 585 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 196 324 5.0E-24 T 28-03-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 ALX04_RS04240 dd73bcd5e96708faabf2035de7c0ab3d 201 Pfam PF00072 Response regulator receiver domain 6 116 1.7E-23 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 ALX04_RS04240 dd73bcd5e96708faabf2035de7c0ab3d 201 SUPERFAMILY SSF52172 1 131 2.85E-29 T 28-03-2018 IPR011006 CheY-like superfamily ALX04_RS04240 dd73bcd5e96708faabf2035de7c0ab3d 201 SUPERFAMILY SSF46894 127 200 4.76E-16 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 ALX04_RS04240 dd73bcd5e96708faabf2035de7c0ab3d 201 Gene3D G3DSA:3.40.50.2300 1 126 4.3E-26 T 28-03-2018 ALX04_RS04240 dd73bcd5e96708faabf2035de7c0ab3d 201 Gene3D G3DSA:1.10.10.10 127 201 2.5E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS04240 dd73bcd5e96708faabf2035de7c0ab3d 201 SMART SM00421 138 195 1.2E-18 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 ALX04_RS04240 dd73bcd5e96708faabf2035de7c0ab3d 201 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 155 171 2.5E-7 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 ALX04_RS04240 dd73bcd5e96708faabf2035de7c0ab3d 201 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 141 155 2.5E-7 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 ALX04_RS04240 dd73bcd5e96708faabf2035de7c0ab3d 201 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 171 183 2.5E-7 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 ALX04_RS04240 dd73bcd5e96708faabf2035de7c0ab3d 201 SMART SM00448 2 115 7.0E-23 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 ALX04_RS04240 dd73bcd5e96708faabf2035de7c0ab3d 201 Pfam PF00196 Bacterial regulatory proteins, luxR family 140 195 1.3E-14 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 ALX04_RS11655 990d33830eab3d1a2effcd091312f81c 379 ProSitePatterns PS00808 ADP-glucose pyrophosphorylase signature 1. 11 30 - T 28-03-2018 IPR005836 ADP-glucose pyrophosphorylase, conserved site GO:0005978|GO:0008878 KEGG: 00500+2.7.7.27|KEGG: 00520+2.7.7.27|MetaCyc: PWY-622 ALX04_RS11655 990d33830eab3d1a2effcd091312f81c 379 TIGRFAM TIGR02091 glgC: glucose-1-phosphate adenylyltransferase 5 358 6.9E-136 T 28-03-2018 IPR011831 Glucose-1-phosphate adenylyltransferase GO:0005978|GO:0008878 KEGG: 00500+2.7.7.27|KEGG: 00520+2.7.7.27|MetaCyc: PWY-622 ALX04_RS11655 990d33830eab3d1a2effcd091312f81c 379 Gene3D G3DSA:2.160.10.10 266 371 1.1E-12 T 28-03-2018 ALX04_RS11655 990d33830eab3d1a2effcd091312f81c 379 SUPERFAMILY SSF51161 266 360 1.15E-14 T 28-03-2018 IPR011004 Trimeric LpxA-like ALX04_RS11655 990d33830eab3d1a2effcd091312f81c 379 Hamap MF_00624 Glucose-1-phosphate adenylyltransferase [glgC]. 2 374 44.901 T 28-03-2018 IPR023049 Glucose-1-phosphate adenylyltransferase GlgC, bacterial GO:0005978|GO:0008878 KEGG: 00500+2.7.7.27|KEGG: 00520+2.7.7.27|MetaCyc: PWY-622 ALX04_RS11655 990d33830eab3d1a2effcd091312f81c 379 Gene3D G3DSA:3.90.550.10 1 265 6.1E-65 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases ALX04_RS11655 990d33830eab3d1a2effcd091312f81c 379 SUPERFAMILY SSF53448 323 340 2.15E-84 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases ALX04_RS11655 990d33830eab3d1a2effcd091312f81c 379 SUPERFAMILY SSF53448 3 262 2.15E-84 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases ALX04_RS11655 990d33830eab3d1a2effcd091312f81c 379 ProSitePatterns PS00810 ADP-glucose pyrophosphorylase signature 3. 189 199 - T 28-03-2018 IPR005836 ADP-glucose pyrophosphorylase, conserved site GO:0005978|GO:0008878 KEGG: 00500+2.7.7.27|KEGG: 00520+2.7.7.27|MetaCyc: PWY-622 ALX04_RS11655 990d33830eab3d1a2effcd091312f81c 379 Pfam PF00483 Nucleotidyl transferase 7 258 1.3E-70 T 28-03-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 ALX04_RS10160 83b8b31d1cbba5420b51e8a33bb3f987 293 ProSitePatterns PS01045 Squalene and phytoene synthases signature 2. 160 185 - T 28-03-2018 IPR019845 Squalene/phytoene synthase, conserved site GO:0016765 Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 ALX04_RS10160 83b8b31d1cbba5420b51e8a33bb3f987 293 SUPERFAMILY SSF48576 14 285 5.04E-72 T 28-03-2018 IPR008949 Isoprenoid synthase domain ALX04_RS10160 83b8b31d1cbba5420b51e8a33bb3f987 293 Pfam PF00494 Squalene/phytoene synthase 23 270 4.0E-62 T 28-03-2018 IPR002060 Squalene/phytoene synthase GO:0009058|GO:0016740 ALX04_RS10160 83b8b31d1cbba5420b51e8a33bb3f987 293 Gene3D G3DSA:1.10.600.10 6 288 3.1E-73 T 28-03-2018 IPR008949 Isoprenoid synthase domain ALX04_RS05630 7e2d805d0b9f3611255b5866fb17f4be 300 Gene3D G3DSA:3.30.2350.10 77 299 2.4E-62 T 28-03-2018 ALX04_RS05630 7e2d805d0b9f3611255b5866fb17f4be 300 TIGRFAM TIGR00005 rluA_subfam: pseudouridine synthase, RluA family 26 292 8.5E-65 T 28-03-2018 IPR006225 Pseudouridine synthase, RluC/RluD GO:0001522|GO:0003723|GO:0009451|GO:0009982 ALX04_RS05630 7e2d805d0b9f3611255b5866fb17f4be 300 Pfam PF00849 RNA pseudouridylate synthase 86 238 3.5E-29 T 28-03-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 ALX04_RS05630 7e2d805d0b9f3611255b5866fb17f4be 300 SUPERFAMILY SSF55120 73 291 8.0E-66 T 28-03-2018 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 ALX04_RS02920 1d4c6c1ad4bdce2a49cb049827de33bb 2217 Gene3D G3DSA:3.10.20.320 1981 2166 0.15 T 28-03-2018 ALX04_RS02920 1d4c6c1ad4bdce2a49cb049827de33bb 2217 Gene3D G3DSA:3.10.20.320 783 860 0.19 T 28-03-2018 ALX04_RS02920 1d4c6c1ad4bdce2a49cb049827de33bb 2217 TIGRFAM TIGR03715 KxYKxGKxW: KxYKxGKxW signal peptide 13 34 3.9E-9 T 28-03-2018 IPR022263 KxYKxGKxW signal peptide ALX04_RS02920 1d4c6c1ad4bdce2a49cb049827de33bb 2217 Gene3D G3DSA:3.40.1840.10 1691 1765 1.6E-12 T 28-03-2018 ALX04_RS02920 1d4c6c1ad4bdce2a49cb049827de33bb 2217 Gene3D G3DSA:3.40.1840.10 1488 1558 5.1E-12 T 28-03-2018 ALX04_RS02920 1d4c6c1ad4bdce2a49cb049827de33bb 2217 Gene3D G3DSA:3.40.1840.10 861 935 2.4E-14 T 28-03-2018 ALX04_RS02920 1d4c6c1ad4bdce2a49cb049827de33bb 2217 Gene3D G3DSA:3.40.1840.10 1900 1969 6.9E-12 T 28-03-2018 ALX04_RS02920 1d4c6c1ad4bdce2a49cb049827de33bb 2217 Gene3D G3DSA:3.40.1840.10 1278 1351 4.4E-16 T 28-03-2018 ALX04_RS02920 1d4c6c1ad4bdce2a49cb049827de33bb 2217 Gene3D G3DSA:3.40.1840.10 1070 1143 2.2E-12 T 28-03-2018 ALX04_RS02920 1d4c6c1ad4bdce2a49cb049827de33bb 2217 Gene3D G3DSA:3.10.20.320 1802 1899 1.0E-4 T 28-03-2018 ALX04_RS02920 1d4c6c1ad4bdce2a49cb049827de33bb 2217 Gene3D G3DSA:3.10.20.320 1388 1487 0.005 T 28-03-2018 ALX04_RS02920 1d4c6c1ad4bdce2a49cb049827de33bb 2217 Gene3D G3DSA:3.10.20.320 1595 1690 9.3E-4 T 28-03-2018 ALX04_RS02920 1d4c6c1ad4bdce2a49cb049827de33bb 2217 Gene3D G3DSA:3.10.20.320 972 1069 5.0E-6 T 28-03-2018 ALX04_RS02920 1d4c6c1ad4bdce2a49cb049827de33bb 2217 Gene3D G3DSA:3.10.20.320 1180 1277 9.2E-5 T 28-03-2018 ALX04_RS02920 1d4c6c1ad4bdce2a49cb049827de33bb 2217 Gene3D G3DSA:2.60.40.1270 690 764 6.4E-10 T 28-03-2018 ALX04_RS02920 1d4c6c1ad4bdce2a49cb049827de33bb 2217 Gene3D G3DSA:2.60.40.1270 608 689 1.2E-11 T 28-03-2018 ALX04_RS03285 e9691f86a12ccf74a454e9d0a979c4ac 448 Pfam PF07690 Major Facilitator Superfamily 24 406 1.1E-23 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 ALX04_RS03285 e9691f86a12ccf74a454e9d0a979c4ac 448 Gene3D G3DSA:1.20.1250.20 241 448 1.5E-22 T 28-03-2018 ALX04_RS03285 e9691f86a12ccf74a454e9d0a979c4ac 448 Gene3D G3DSA:1.20.1250.20 11 231 4.7E-22 T 28-03-2018 ALX04_RS03285 e9691f86a12ccf74a454e9d0a979c4ac 448 SUPERFAMILY SSF103473 19 445 2.35E-39 T 28-03-2018 IPR020846 Major facilitator superfamily domain ALX04_RS12880 a3ce82a26af1da3866067c7a4716fa83 219 Gene3D G3DSA:3.40.50.300 1 219 8.8E-58 T 28-03-2018 ALX04_RS12880 a3ce82a26af1da3866067c7a4716fa83 219 ProSitePatterns PS00211 ABC transporters family signature. 138 152 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 ALX04_RS12880 a3ce82a26af1da3866067c7a4716fa83 219 SMART SM00382 28 213 3.3E-10 T 28-03-2018 IPR003593 AAA+ ATPase domain ALX04_RS12880 a3ce82a26af1da3866067c7a4716fa83 219 Pfam PF00005 ABC transporter 20 165 1.9E-32 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 ALX04_RS12880 a3ce82a26af1da3866067c7a4716fa83 219 SUPERFAMILY SSF52540 18 216 4.33E-55 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase ALX04_RS04870 2bc4f6f570d71d5a8557f1fcba6ae6f1 170 SMART SM00507 68 124 1.2E-6 T 28-03-2018 IPR003615 HNH nuclease ALX04_RS04870 2bc4f6f570d71d5a8557f1fcba6ae6f1 170 Pfam PF01844 HNH endonuclease 81 123 1.8E-7 T 28-03-2018 IPR002711 HNH endonuclease GO:0003676|GO:0004519 ALX04_RS04870 2bc4f6f570d71d5a8557f1fcba6ae6f1 170 Gene3D G3DSA:3.40.1800.10 47 139 2.9E-12 T 28-03-2018 ALX04_RS15405 ed83f6f6ce92c423be22a84f9e940a7a 176 Gene3D G3DSA:3.40.50.1240 1 162 2.8E-22 T 28-03-2018 IPR029033 Histidine phosphatase superfamily ALX04_RS15405 ed83f6f6ce92c423be22a84f9e940a7a 176 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 3 158 5.1E-20 T 28-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 ALX04_RS15405 ed83f6f6ce92c423be22a84f9e940a7a 176 SMART SM00855 2 159 8.5E-6 T 28-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 ALX04_RS15405 ed83f6f6ce92c423be22a84f9e940a7a 176 SUPERFAMILY SSF53254 1 172 2.16E-24 T 28-03-2018 IPR029033 Histidine phosphatase superfamily ALX04_RS11250 6d511a1c2c3a77f87819f5ebebe4943a 683 Gene3D G3DSA:3.40.50.2300 391 481 2.4E-14 T 28-03-2018 ALX04_RS11250 6d511a1c2c3a77f87819f5ebebe4943a 683 SUPERFAMILY SSF63520 291 386 8.89E-18 T 28-03-2018 IPR011608 PRD domain GO:0006355 ALX04_RS11250 6d511a1c2c3a77f87819f5ebebe4943a 683 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 541 680 1.1E-16 T 28-03-2018 IPR002178 PTS EIIA type-2 domain ALX04_RS11250 6d511a1c2c3a77f87819f5ebebe4943a 683 Gene3D G3DSA:3.40.930.10 537 683 1.6E-19 T 28-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 ALX04_RS11250 6d511a1c2c3a77f87819f5ebebe4943a 683 Pfam PF05043 Mga helix-turn-helix domain 97 163 1.0E-4 T 28-03-2018 IPR007737 Mga helix-turn-helix domain ALX04_RS11250 6d511a1c2c3a77f87819f5ebebe4943a 683 Gene3D G3DSA:1.10.10.10 91 158 1.5E-9 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS11250 6d511a1c2c3a77f87819f5ebebe4943a 683 Gene3D G3DSA:1.10.10.10 2 69 3.5E-5 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS11250 6d511a1c2c3a77f87819f5ebebe4943a 683 SUPERFAMILY SSF52794 395 470 4.18E-7 T 28-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 ALX04_RS11250 6d511a1c2c3a77f87819f5ebebe4943a 683 Pfam PF00874 PRD domain 309 382 3.2E-15 T 28-03-2018 IPR011608 PRD domain GO:0006355 ALX04_RS11250 6d511a1c2c3a77f87819f5ebebe4943a 683 SUPERFAMILY SSF55804 538 680 9.07E-25 T 28-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 ALX04_RS11250 6d511a1c2c3a77f87819f5ebebe4943a 683 Gene3D G3DSA:1.10.1790.10 282 386 1.2E-16 T 28-03-2018 IPR011608 PRD domain GO:0006355 ALX04_RS03110 2d26040e1281b0f9da0844fbbcc4519b 567 SUPERFAMILY SSF103473 6 198 4.32E-52 T 28-03-2018 IPR020846 Major facilitator superfamily domain ALX04_RS03110 2d26040e1281b0f9da0844fbbcc4519b 567 SUPERFAMILY SSF103473 244 413 4.32E-52 T 28-03-2018 IPR020846 Major facilitator superfamily domain ALX04_RS03110 2d26040e1281b0f9da0844fbbcc4519b 567 Gene3D G3DSA:1.20.1250.20 3 193 5.1E-27 T 28-03-2018 ALX04_RS03110 2d26040e1281b0f9da0844fbbcc4519b 567 Gene3D G3DSA:1.20.1250.20 247 562 8.7E-27 T 28-03-2018 ALX04_RS03110 2d26040e1281b0f9da0844fbbcc4519b 567 Pfam PF07690 Major Facilitator Superfamily 13 403 5.2E-42 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 ALX04_RS03110 2d26040e1281b0f9da0844fbbcc4519b 567 PRINTS PR01036 Tetracycline resistance protein TetB signature 132 156 4.4E-11 T 28-03-2018 ALX04_RS03110 2d26040e1281b0f9da0844fbbcc4519b 567 PRINTS PR01036 Tetracycline resistance protein TetB signature 102 122 4.4E-11 T 28-03-2018 ALX04_RS03110 2d26040e1281b0f9da0844fbbcc4519b 567 PRINTS PR01036 Tetracycline resistance protein TetB signature 332 352 4.4E-11 T 28-03-2018 ALX04_RS03110 2d26040e1281b0f9da0844fbbcc4519b 567 PRINTS PR01036 Tetracycline resistance protein TetB signature 297 321 4.4E-11 T 28-03-2018 ALX04_RS03110 2d26040e1281b0f9da0844fbbcc4519b 567 PRINTS PR01036 Tetracycline resistance protein TetB signature 11 35 4.4E-11 T 28-03-2018 ALX04_RS01005 c26c1958c94d0079677fc05496277c58 238 Gene3D G3DSA:1.20.1080.10 1 237 6.1E-61 T 28-03-2018 IPR023271 Aquaporin-like Reactome: R-HSA-432047 ALX04_RS01005 c26c1958c94d0079677fc05496277c58 238 Pfam PF00230 Major intrinsic protein 3 229 5.7E-31 T 28-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 ALX04_RS01005 c26c1958c94d0079677fc05496277c58 238 SUPERFAMILY SSF81338 3 236 1.44E-53 T 28-03-2018 IPR023271 Aquaporin-like Reactome: R-HSA-432047 ALX04_RS01005 c26c1958c94d0079677fc05496277c58 238 PRINTS PR00783 Major intrinsic protein family signature 3 22 1.5E-25 T 28-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 ALX04_RS01005 c26c1958c94d0079677fc05496277c58 238 PRINTS PR00783 Major intrinsic protein family signature 79 98 1.5E-25 T 28-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 ALX04_RS01005 c26c1958c94d0079677fc05496277c58 238 PRINTS PR00783 Major intrinsic protein family signature 137 155 1.5E-25 T 28-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 ALX04_RS01005 c26c1958c94d0079677fc05496277c58 238 PRINTS PR00783 Major intrinsic protein family signature 166 188 1.5E-25 T 28-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 ALX04_RS01005 c26c1958c94d0079677fc05496277c58 238 PRINTS PR00783 Major intrinsic protein family signature 214 234 1.5E-25 T 28-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 ALX04_RS07260 7957c95a257cd3bcb73f044f78fb4cf5 257 TIGRFAM TIGR03716 R_switched_YkoY: integral membrane protein, YkoY family 30 241 1.2E-72 T 28-03-2018 IPR022493 Integral membrane YkoY ALX04_RS07260 7957c95a257cd3bcb73f044f78fb4cf5 257 Pfam PF03741 Integral membrane protein TerC family 33 211 2.1E-47 T 28-03-2018 IPR005496 Integral membrane protein TerC GO:0016021 ALX04_RS03505 c8c5bbd55c5b573f826d7ba21d44db11 551 Gene3D G3DSA:3.10.410.10 439 527 6.4E-37 T 28-03-2018 ALX04_RS03505 c8c5bbd55c5b573f826d7ba21d44db11 551 Hamap MF_01543 Formate--tetrahydrofolate ligase [fhs]. 1 551 47.024 T 28-03-2018 IPR000559 Formate-tetrahydrofolate ligase, FTHFS GO:0004329|GO:0005524 KEGG: 00670+6.3.4.3|KEGG: 00720+6.3.4.3|MetaCyc: PWY-1722|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-196757 ALX04_RS03505 c8c5bbd55c5b573f826d7ba21d44db11 551 ProSitePatterns PS00721 Formate--tetrahydrofolate ligase signature 1. 99 109 - T 28-03-2018 IPR020628 Formate-tetrahydrofolate ligase, FTHFS, conserved site GO:0005524 KEGG: 00670+6.3.4.3|KEGG: 00720+6.3.4.3|MetaCyc: PWY-1722|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-196757 ALX04_RS03505 c8c5bbd55c5b573f826d7ba21d44db11 551 ProSitePatterns PS00722 Formate--tetrahydrofolate ligase signature 2. 324 335 - T 28-03-2018 IPR020628 Formate-tetrahydrofolate ligase, FTHFS, conserved site GO:0005524 KEGG: 00670+6.3.4.3|KEGG: 00720+6.3.4.3|MetaCyc: PWY-1722|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-196757 ALX04_RS03505 c8c5bbd55c5b573f826d7ba21d44db11 551 Gene3D G3DSA:3.40.50.300 232 437 1.3E-66 T 28-03-2018 ALX04_RS03505 c8c5bbd55c5b573f826d7ba21d44db11 551 Gene3D G3DSA:3.40.50.300 11 231 3.5E-84 T 28-03-2018 ALX04_RS03505 c8c5bbd55c5b573f826d7ba21d44db11 551 SUPERFAMILY SSF52540 3 549 9.38E-230 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase ALX04_RS03505 c8c5bbd55c5b573f826d7ba21d44db11 551 Pfam PF01268 Formate--tetrahydrofolate ligase 1 551 1.7E-255 T 28-03-2018 IPR000559 Formate-tetrahydrofolate ligase, FTHFS GO:0004329|GO:0005524 KEGG: 00670+6.3.4.3|KEGG: 00720+6.3.4.3|MetaCyc: PWY-1722|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-196757 ALX04_RS06330 66d46832ea281814b74b949954d2068b 519 Pfam PF03009 Glycerophosphoryl diester phosphodiesterase family 276 494 9.1E-16 T 28-03-2018 IPR030395 Glycerophosphodiester phosphodiesterase domain GO:0006629|GO:0008081 ALX04_RS06330 66d46832ea281814b74b949954d2068b 519 Gene3D G3DSA:3.20.20.190 261 509 1.2E-40 T 28-03-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 ALX04_RS06330 66d46832ea281814b74b949954d2068b 519 SUPERFAMILY SSF51695 272 499 8.89E-46 T 28-03-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 ALX04_RS00890 07b31d19bf585ea596cdf457e335a07f 340 SUPERFAMILY SSF111331 1 301 3.05E-76 T 28-03-2018 IPR016064 NAD kinase/diacylglycerol kinase-like domain ALX04_RS00890 07b31d19bf585ea596cdf457e335a07f 340 Pfam PF00781 Diacylglycerol kinase catalytic domain 5 129 1.1E-32 T 28-03-2018 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 ALX04_RS00890 07b31d19bf585ea596cdf457e335a07f 340 Gene3D G3DSA:3.40.50.10330 1 134 1.7E-30 T 28-03-2018 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, domain 1 GO:0003951|GO:0008152 ALX04_RS00890 07b31d19bf585ea596cdf457e335a07f 340 TIGRFAM TIGR00147 TIGR00147: lipid kinase, YegS/Rv2252/BmrU family 3 296 1.3E-81 T 28-03-2018 IPR005218 Diacylglycerol/lipid kinase ALX04_RS00890 07b31d19bf585ea596cdf457e335a07f 340 SMART SM00046 4 128 7.0E-8 T 28-03-2018 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 ALX04_RS08095 2e236f8253753794cfca88f86b703094 248 Gene3D G3DSA:3.40.50.720 8 247 6.2E-63 T 28-03-2018 ALX04_RS08095 2e236f8253753794cfca88f86b703094 248 SUPERFAMILY SSF51735 6 247 9.43E-66 T 28-03-2018 IPR016040 NAD(P)-binding domain ALX04_RS08095 2e236f8253753794cfca88f86b703094 248 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 132 140 1.1E-5 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR ALX04_RS08095 2e236f8253753794cfca88f86b703094 248 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 152 171 1.1E-5 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR ALX04_RS08095 2e236f8253753794cfca88f86b703094 248 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 78 89 1.1E-5 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR ALX04_RS08095 2e236f8253753794cfca88f86b703094 248 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 15 245 2.4E-51 T 28-03-2018 ALX04_RS08095 2e236f8253753794cfca88f86b703094 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 10 27 2.7E-36 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR ALX04_RS08095 2e236f8253753794cfca88f86b703094 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 173 190 2.7E-36 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR ALX04_RS08095 2e236f8253753794cfca88f86b703094 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 126 142 2.7E-36 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR ALX04_RS08095 2e236f8253753794cfca88f86b703094 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 152 171 2.7E-36 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR ALX04_RS08095 2e236f8253753794cfca88f86b703094 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 78 89 2.7E-36 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR ALX04_RS08095 2e236f8253753794cfca88f86b703094 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 209 229 2.7E-36 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR ALX04_RS02970 0d1617fb6f7b098aa9c1a6f5f59ca37e 264 Hamap MF_00131 Tryptophan synthase alpha chain [trpA]. 9 254 34.806 T 28-03-2018 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 ALX04_RS02970 0d1617fb6f7b098aa9c1a6f5f59ca37e 264 TIGRFAM TIGR00262 trpA: tryptophan synthase, alpha subunit 9 249 3.3E-81 T 28-03-2018 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 ALX04_RS02970 0d1617fb6f7b098aa9c1a6f5f59ca37e 264 Gene3D G3DSA:3.20.20.70 4 264 5.8E-71 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 ALX04_RS02970 0d1617fb6f7b098aa9c1a6f5f59ca37e 264 SUPERFAMILY SSF51366 2 245 1.26E-82 T 28-03-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 ALX04_RS02970 0d1617fb6f7b098aa9c1a6f5f59ca37e 264 ProSitePatterns PS00167 Tryptophan synthase alpha chain signature. 43 56 - T 28-03-2018 IPR018204 Tryptophan synthase, alpha chain, active site GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 ALX04_RS02970 0d1617fb6f7b098aa9c1a6f5f59ca37e 264 Pfam PF00290 Tryptophan synthase alpha chain 9 240 2.8E-89 T 28-03-2018 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 ALX04_RS02985 ea1df33c202e796809d62ba17fec09c8 166 Gene3D G3DSA:3.40.630.30 9 153 1.5E-11 T 28-03-2018 ALX04_RS02985 ea1df33c202e796809d62ba17fec09c8 166 Pfam PF00583 Acetyltransferase (GNAT) family 40 136 3.4E-6 T 28-03-2018 IPR000182 GNAT domain GO:0008080 ALX04_RS02985 ea1df33c202e796809d62ba17fec09c8 166 SUPERFAMILY SSF55729 27 144 1.74E-12 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase ALX04_RS07725 1eee1765db5a076f99799ffd4f3eede2 125 Gene3D G3DSA:1.10.1660.10 65 125 1.4E-5 T 28-03-2018 ALX04_RS07725 1eee1765db5a076f99799ffd4f3eede2 125 SMART SM00422 13 78 1.9E-12 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 ALX04_RS07725 1eee1765db5a076f99799ffd4f3eede2 125 Gene3D G3DSA:1.10.1660.10 9 64 3.7E-16 T 28-03-2018 ALX04_RS07725 1eee1765db5a076f99799ffd4f3eede2 125 SUPERFAMILY SSF46955 13 120 4.4E-23 T 28-03-2018 IPR009061 Putative DNA-binding domain ALX04_RS07725 1eee1765db5a076f99799ffd4f3eede2 125 Pfam PF13411 MerR HTH family regulatory protein 13 73 1.4E-13 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 ALX04_RS03610 dda5d918082c54aa946123b8f7995f4d 262 SUPERFAMILY SSF54197 13 128 4.08E-23 T 28-03-2018 IPR011146 HIT-like domain GO:0003824 ALX04_RS03610 dda5d918082c54aa946123b8f7995f4d 262 Pfam PF16285 Domain of unknown function (DUF4931) 8 252 1.5E-76 T 28-03-2018 ALX04_RS03610 dda5d918082c54aa946123b8f7995f4d 262 Gene3D G3DSA:3.30.428.10 56 130 1.6E-12 T 28-03-2018 IPR011146 HIT-like domain GO:0003824 ALX04_RS03610 dda5d918082c54aa946123b8f7995f4d 262 PIRSF PIRSF031505 1 256 2.2E-133 T 28-03-2018 IPR012361 Galactose-1-phosphate uridylyltransferase, short form, putative ALX04_RS05520 bda09e79ccd6039741d01bcc701a32a9 291 Pfam PF03799 Cell division protein FtsQ 169 276 6.9E-7 T 28-03-2018 IPR005548 Cell division protein FtsQ/DivIB ALX04_RS05520 bda09e79ccd6039741d01bcc701a32a9 291 Pfam PF08478 POTRA domain, FtsQ-type 90 159 5.4E-5 T 28-03-2018 IPR013685 POTRA domain, FtsQ-type ALX04_RS05520 bda09e79ccd6039741d01bcc701a32a9 291 Hamap MF_00912 Cell division protein DivIB [divIB]. 27 291 33.976 T 28-03-2018 IPR026580 Cell division protein DivIB ALX04_RS02300 8913ae41f9897a7b58441d8132212458 238 Pfam PF01027 Inhibitor of apoptosis-promoting Bax1 20 232 5.0E-47 T 28-03-2018 IPR006214 Bax inhibitor 1-related ALX04_RS01820 fb4392a2eff6de9607aa354158b6b552 756 Gene3D G3DSA:1.20.1580.10 99 132 2.7E-8 T 28-03-2018 ALX04_RS01820 fb4392a2eff6de9607aa354158b6b552 756 Gene3D G3DSA:3.40.50.300 463 754 1.5E-48 T 28-03-2018 ALX04_RS01820 fb4392a2eff6de9607aa354158b6b552 756 ProSitePatterns PS00211 ABC transporters family signature. 340 354 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 ALX04_RS01820 fb4392a2eff6de9607aa354158b6b552 756 SMART SM00382 31 417 5.9 T 28-03-2018 IPR003593 AAA+ ATPase domain ALX04_RS01820 fb4392a2eff6de9607aa354158b6b552 756 SMART SM00382 479 720 0.11 T 28-03-2018 IPR003593 AAA+ ATPase domain ALX04_RS01820 fb4392a2eff6de9607aa354158b6b552 756 ProSitePatterns PS00211 ABC transporters family signature. 647 661 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 ALX04_RS01820 fb4392a2eff6de9607aa354158b6b552 756 Gene3D G3DSA:1.10.8.280 153 262 1.1E-20 T 28-03-2018 ALX04_RS01820 fb4392a2eff6de9607aa354158b6b552 756 SUPERFAMILY SSF52540 466 727 3.16E-39 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase ALX04_RS01820 fb4392a2eff6de9607aa354158b6b552 756 Pfam PF00005 ABC transporter 470 675 1.8E-13 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 ALX04_RS01820 fb4392a2eff6de9607aa354158b6b552 756 Gene3D G3DSA:3.40.50.300 278 462 2.0E-23 T 28-03-2018 ALX04_RS01820 fb4392a2eff6de9607aa354158b6b552 756 SUPERFAMILY SSF52540 19 190 9.84E-30 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase ALX04_RS01820 fb4392a2eff6de9607aa354158b6b552 756 SUPERFAMILY SSF52540 291 432 9.84E-30 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase ALX04_RS01820 fb4392a2eff6de9607aa354158b6b552 756 Gene3D G3DSA:3.40.50.300 20 65 0.019 T 28-03-2018 ALX04_RS01320 c0b4ece0277f274b842abd4286bc5b1d 298 SMART SM01350 167 298 2.9E-5 T 28-03-2018 IPR006114 6-phosphogluconate dehydrogenase, C-terminal GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 ALX04_RS01320 c0b4ece0277f274b842abd4286bc5b1d 298 Gene3D G3DSA:1.10.1040.10 169 297 5.6E-37 T 28-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 ALX04_RS01320 c0b4ece0277f274b842abd4286bc5b1d 298 Gene3D G3DSA:3.40.50.720 1 168 8.7E-30 T 28-03-2018 ALX04_RS01320 c0b4ece0277f274b842abd4286bc5b1d 298 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 2 154 7.1E-41 T 28-03-2018 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0004616|GO:0055114 ALX04_RS01320 c0b4ece0277f274b842abd4286bc5b1d 298 SUPERFAMILY SSF51735 1 156 2.47E-42 T 28-03-2018 IPR016040 NAD(P)-binding domain ALX04_RS01320 c0b4ece0277f274b842abd4286bc5b1d 298 ProSitePatterns PS00461 6-phosphogluconate dehydrogenase signature. 235 247 - T 28-03-2018 IPR006184 6-phosphogluconate-binding site GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 ALX04_RS01320 c0b4ece0277f274b842abd4286bc5b1d 298 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 1 24 1.3E-31 T 28-03-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 ALX04_RS01320 c0b4ece0277f274b842abd4286bc5b1d 298 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 59 88 1.3E-31 T 28-03-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 ALX04_RS01320 c0b4ece0277f274b842abd4286bc5b1d 298 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 231 258 1.3E-31 T 28-03-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 ALX04_RS01320 c0b4ece0277f274b842abd4286bc5b1d 298 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 156 184 1.3E-31 T 28-03-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 ALX04_RS01320 c0b4ece0277f274b842abd4286bc5b1d 298 TIGRFAM TIGR00872 gnd_rel: 6-phosphogluconate dehydrogenase (decarboxylating) 1 296 4.3E-123 T 28-03-2018 IPR004849 6-phosphogluconate dehydrogenase, YqeC-type GO:0055114 ALX04_RS01320 c0b4ece0277f274b842abd4286bc5b1d 298 Pfam PF00393 6-phosphogluconate dehydrogenase, C-terminal domain 167 276 2.7E-23 T 28-03-2018 IPR006114 6-phosphogluconate dehydrogenase, C-terminal GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 ALX04_RS01320 c0b4ece0277f274b842abd4286bc5b1d 298 SUPERFAMILY SSF48179 165 295 4.01E-39 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 ALX04_RS05610 4a6255bb71b924be4147f2b728ff03b9 384 Pfam PF01594 AI-2E family transporter 45 359 6.1E-73 T 28-03-2018 IPR002549 Transmembrane protein TqsA-like ALX04_RS15760 14742c2daebe19014606b47b57b25ad2 155 SUPERFAMILY SSF47240 5 151 2.17E-42 T 28-03-2018 IPR009078 Ferritin-like superfamily ALX04_RS15760 14742c2daebe19014606b47b57b25ad2 155 PIRSF PIRSF005900 1 153 1.9E-42 T 28-03-2018 IPR002177 DNA-binding protein Dps GO:0006950|GO:0055114 ALX04_RS15760 14742c2daebe19014606b47b57b25ad2 155 Gene3D G3DSA:1.20.1260.10 2 155 7.9E-40 T 28-03-2018 IPR012347 Ferritin-related ALX04_RS15760 14742c2daebe19014606b47b57b25ad2 155 PRINTS PR01346 Helicobacter neutrophil-activating protein A family signature 28 44 5.4E-14 T 28-03-2018 IPR002177 DNA-binding protein Dps GO:0006950|GO:0055114 ALX04_RS15760 14742c2daebe19014606b47b57b25ad2 155 PRINTS PR01346 Helicobacter neutrophil-activating protein A family signature 52 68 5.4E-14 T 28-03-2018 IPR002177 DNA-binding protein Dps GO:0006950|GO:0055114 ALX04_RS15760 14742c2daebe19014606b47b57b25ad2 155 PRINTS PR01346 Helicobacter neutrophil-activating protein A family signature 125 143 5.4E-14 T 28-03-2018 IPR002177 DNA-binding protein Dps GO:0006950|GO:0055114 ALX04_RS15760 14742c2daebe19014606b47b57b25ad2 155 Pfam PF00210 Ferritin-like domain 9 148 1.7E-27 T 28-03-2018 IPR008331 Ferritin/DPS protein domain GO:0006879|GO:0008199 ALX04_RS15760 14742c2daebe19014606b47b57b25ad2 155 ProSitePatterns PS00818 Dps protein family signature 1. 28 44 - T 28-03-2018 IPR023188 DNA-binding protein Dps, conserved site GO:0016722|GO:0055114 ALX04_RS12660 77e8671adc0cc54d27f8e0d243a50651 180 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 123 151 - T 28-03-2018 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 ALX04_RS12660 77e8671adc0cc54d27f8e0d243a50651 180 SUPERFAMILY SSF51161 6 165 7.62E-44 T 28-03-2018 IPR011004 Trimeric LpxA-like ALX04_RS12660 77e8671adc0cc54d27f8e0d243a50651 180 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 69 103 0.003 T 28-03-2018 IPR001451 Hexapeptide repeat ALX04_RS12660 77e8671adc0cc54d27f8e0d243a50651 180 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 116 147 3.2E-7 T 28-03-2018 IPR001451 Hexapeptide repeat ALX04_RS12660 77e8671adc0cc54d27f8e0d243a50651 180 Gene3D G3DSA:1.10.3130.10 2 55 4.2E-18 T 28-03-2018 ALX04_RS12660 77e8671adc0cc54d27f8e0d243a50651 180 Gene3D G3DSA:2.160.10.10 56 179 5.6E-28 T 28-03-2018 ALX04_RS12660 77e8671adc0cc54d27f8e0d243a50651 180 PIRSF PIRSF000441 2 180 4.3E-59 T 28-03-2018 IPR005881 Serine O-acetyltransferase GO:0005737|GO:0006535|GO:0009001 KEGG: 00270+2.3.1.30|KEGG: 00920+2.3.1.30|MetaCyc: PWY-6936|MetaCyc: PWY-7274 ALX04_RS08570 445397f1413e6a744dba104334939015 138 SUPERFAMILY SSF53850 4 137 8.51E-6 T 28-03-2018 ALX04_RS03805 45d314e9ce05b4a5dfca519f0d23b98a 284 SUPERFAMILY SSF52540 10 214 2.22E-42 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase ALX04_RS03805 45d314e9ce05b4a5dfca519f0d23b98a 284 TIGRFAM TIGR03596 GTPase_YlqF: ribosome biogenesis GTP-binding protein YlqF 4 276 1.0E-105 T 28-03-2018 IPR019991 GTP-binding protein, ribosome biogenesis ALX04_RS03805 45d314e9ce05b4a5dfca519f0d23b98a 284 Gene3D G3DSA:1.20.120.430 10 184 1.2E-26 T 28-03-2018 ALX04_RS03805 45d314e9ce05b4a5dfca519f0d23b98a 284 Gene3D G3DSA:1.10.1580.10 185 270 2.2E-13 T 28-03-2018 IPR023179 GTP-binding protein, orthogonal bundle domain ALX04_RS03805 45d314e9ce05b4a5dfca519f0d23b98a 284 PIRSF PIRSF006230 1 281 2.4E-101 T 28-03-2018 IPR016478 GTPase, MTG1 ALX04_RS03805 45d314e9ce05b4a5dfca519f0d23b98a 284 Pfam PF01926 50S ribosome-binding GTPase 124 219 5.1E-16 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 ALX04_RS00515 450c0f2d9eae995bf508347d82f0885c 127 Gene3D G3DSA:3.90.1030.10 1 127 8.0E-45 T 28-03-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 ALX04_RS00515 450c0f2d9eae995bf508347d82f0885c 127 Pfam PF01196 Ribosomal protein L17 16 126 6.5E-37 T 28-03-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 ALX04_RS00515 450c0f2d9eae995bf508347d82f0885c 127 Hamap MF_01368 50S ribosomal protein L17 [rplQ]. 1 126 26.063 T 28-03-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 ALX04_RS00515 450c0f2d9eae995bf508347d82f0885c 127 TIGRFAM TIGR00059 L17: ribosomal protein bL17 2 127 1.4E-42 T 28-03-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 ALX04_RS00515 450c0f2d9eae995bf508347d82f0885c 127 SUPERFAMILY SSF64263 2 127 5.36E-40 T 28-03-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 ALX04_RS05640 d359cad93ffd39b3cb55f1216287a035 220 Gene3D G3DSA:1.10.287.860 147 195 2.0E-21 T 28-03-2018 ALX04_RS05640 d359cad93ffd39b3cb55f1216287a035 220 Gene3D G3DSA:3.30.460.10 1 145 5.1E-39 T 28-03-2018 ALX04_RS05640 d359cad93ffd39b3cb55f1216287a035 220 Pfam PF04607 Region found in RelA / SpoT proteins 43 162 1.2E-38 T 28-03-2018 IPR007685 RelA/SpoT GO:0015969 ALX04_RS05640 d359cad93ffd39b3cb55f1216287a035 220 SMART SM00954 43 164 1.2E-45 T 28-03-2018 IPR007685 RelA/SpoT GO:0015969 ALX04_RS05640 d359cad93ffd39b3cb55f1216287a035 220 SUPERFAMILY SSF81301 3 197 4.9E-62 T 28-03-2018 ALX04_RS14725 f00b5cf5486688e759166ca81d284e93 324 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 227 243 - T 28-03-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site ALX04_RS14725 f00b5cf5486688e759166ca81d284e93 324 Gene3D G3DSA:3.40.50.720 115 290 1.2E-52 T 28-03-2018 ALX04_RS14725 f00b5cf5486688e759166ca81d284e93 324 SUPERFAMILY SSF52283 1 138 1.49E-31 T 28-03-2018 ALX04_RS14725 f00b5cf5486688e759166ca81d284e93 324 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 109 287 3.7E-60 T 28-03-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 ALX04_RS14725 f00b5cf5486688e759166ca81d284e93 324 Gene3D G3DSA:3.40.50.720 1 114 1.5E-31 T 28-03-2018 ALX04_RS14725 f00b5cf5486688e759166ca81d284e93 324 SUPERFAMILY SSF51735 101 287 3.24E-59 T 28-03-2018 IPR016040 NAD(P)-binding domain ALX04_RS14725 f00b5cf5486688e759166ca81d284e93 324 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 24 319 5.0E-31 T 28-03-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0008152|GO:0016616|GO:0051287|GO:0055114 ALX04_RS14725 f00b5cf5486688e759166ca81d284e93 324 ProSitePatterns PS00670 D-isomer specific 2-hydroxyacid dehydrogenases signature 2. 198 220 - T 28-03-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site ALX04_RS00460 6883e7bcdc30dc33726fe9bf6c8f3b15 118 SUPERFAMILY SSF53137 7 116 1.22E-51 T 28-03-2018 ALX04_RS00460 6883e7bcdc30dc33726fe9bf6c8f3b15 118 Hamap MF_01337_B 50S ribosomal protein L18 [rplR]. 6 118 28.982 T 28-03-2018 IPR004389 Ribosomal protein L18, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 ALX04_RS00460 6883e7bcdc30dc33726fe9bf6c8f3b15 118 Gene3D G3DSA:3.30.420.100 2 118 1.1E-41 T 28-03-2018 ALX04_RS00460 6883e7bcdc30dc33726fe9bf6c8f3b15 118 TIGRFAM TIGR00060 L18_bact: ribosomal protein uL18 7 118 6.4E-47 T 28-03-2018 IPR004389 Ribosomal protein L18, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 ALX04_RS00460 6883e7bcdc30dc33726fe9bf6c8f3b15 118 Pfam PF00861 Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast 6 118 8.6E-50 T 28-03-2018 IPR005484 Ribosomal protein L18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 ALX04_RS12970 81075e5f642653df9236ebf1029134e9 365 ProSitePatterns PS00211 ABC transporters family signature. 139 153 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 ALX04_RS12970 81075e5f642653df9236ebf1029134e9 365 Pfam PF00005 ABC transporter 24 166 1.3E-36 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 ALX04_RS12970 81075e5f642653df9236ebf1029134e9 365 Gene3D G3DSA:3.40.50.300 4 249 1.3E-77 T 28-03-2018 ALX04_RS12970 81075e5f642653df9236ebf1029134e9 365 SMART SM00382 33 216 3.2E-20 T 28-03-2018 IPR003593 AAA+ ATPase domain ALX04_RS12970 81075e5f642653df9236ebf1029134e9 365 SUPERFAMILY SSF52540 8 249 6.41E-87 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase ALX04_RS12970 81075e5f642653df9236ebf1029134e9 365 Pfam PF08402 TOBE domain 277 346 2.2E-7 T 28-03-2018 IPR013611 Transport-associated OB, type 2 GO:0005215|GO:0005524|GO:0006810|GO:0016820|GO:0043190 ALX04_RS12970 81075e5f642653df9236ebf1029134e9 365 SUPERFAMILY SSF50331 241 346 2.13E-11 T 28-03-2018 IPR008995 Molybdate/tungstate binding, C-terminal ALX04_RS12970 81075e5f642653df9236ebf1029134e9 365 TIGRFAM TIGR01187 potA: polyamine ABC transporter, ATP-binding protein 39 310 1.3E-109 T 28-03-2018 IPR005893 Spermidine/putrescine ABC transporter, ATP-binding subunit GO:0015417|GO:0015846|GO:0043190 ALX04_RS12970 81075e5f642653df9236ebf1029134e9 365 Gene3D G3DSA:2.40.50.100 294 354 0.38 T 28-03-2018 ALX04_RS04665 a5b87dd1108de68c289167f913a106dd 332 Gene3D G3DSA:3.40.50.720 2 113 7.6E-18 T 28-03-2018 ALX04_RS04665 a5b87dd1108de68c289167f913a106dd 332 ProSitePatterns PS00670 D-isomer specific 2-hydroxyacid dehydrogenases signature 2. 195 217 - T 28-03-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site ALX04_RS04665 a5b87dd1108de68c289167f913a106dd 332 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 112 298 1.7E-55 T 28-03-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 ALX04_RS04665 a5b87dd1108de68c289167f913a106dd 332 SUPERFAMILY SSF52283 2 136 1.32E-37 T 28-03-2018 ALX04_RS04665 a5b87dd1108de68c289167f913a106dd 332 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 224 240 - T 28-03-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site ALX04_RS04665 a5b87dd1108de68c289167f913a106dd 332 ProSitePatterns PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. 148 175 - T 28-03-2018 IPR029752 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 ALX04_RS04665 a5b87dd1108de68c289167f913a106dd 332 Gene3D G3DSA:3.40.50.720 114 301 3.2E-50 T 28-03-2018 ALX04_RS04665 a5b87dd1108de68c289167f913a106dd 332 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 7 329 4.8E-29 T 28-03-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0008152|GO:0016616|GO:0051287|GO:0055114 ALX04_RS04665 a5b87dd1108de68c289167f913a106dd 332 SUPERFAMILY SSF51735 103 300 7.74E-54 T 28-03-2018 IPR016040 NAD(P)-binding domain ALX04_RS07730 ee22badf79fab60173cc86091b7d8431 314 SUPERFAMILY SSF51735 122 282 1.2E-33 T 28-03-2018 IPR016040 NAD(P)-binding domain ALX04_RS07730 ee22badf79fab60173cc86091b7d8431 314 SUPERFAMILY SSF50129 1 155 2.28E-34 T 28-03-2018 IPR011032 GroES-like ALX04_RS07730 ee22badf79fab60173cc86091b7d8431 314 Pfam PF13602 Zinc-binding dehydrogenase 192 310 1.7E-19 T 28-03-2018 ALX04_RS07730 ee22badf79fab60173cc86091b7d8431 314 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 28 92 1.6E-5 T 28-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 ALX04_RS07730 ee22badf79fab60173cc86091b7d8431 314 Gene3D G3DSA:3.90.180.10 1 215 1.3E-58 T 28-03-2018 ALX04_RS07730 ee22badf79fab60173cc86091b7d8431 314 SMART SM00829 10 310 2.2E-25 T 28-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 ALX04_RS07730 ee22badf79fab60173cc86091b7d8431 314 Gene3D G3DSA:3.90.180.10 216 314 6.2E-4 T 28-03-2018 ALX04_RS07730 ee22badf79fab60173cc86091b7d8431 314 ProSitePatterns PS01162 Quinone oxidoreductase / zeta-crystallin signature. 150 171 - T 28-03-2018 IPR002364 Quinone oxidoreductase/zeta-crystallin, conserved site GO:0008270|GO:0016491 ALX04_RS12625 c431fe70a0b409d7190c2b0c726c3e06 425 Pfam PF02378 Phosphotransferase system, EIIC 29 352 4.1E-54 T 28-03-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 ALX04_RS12625 c431fe70a0b409d7190c2b0c726c3e06 425 PIRSF PIRSF006351 1 425 3.1E-154 T 28-03-2018 IPR004796 Phosphotransferase system, cellobiose-type IIC component GO:0008982|GO:0009401|GO:0016021 ALX04_RS12625 c431fe70a0b409d7190c2b0c726c3e06 425 TIGRFAM TIGR00410 lacE: PTS system, lactose/cellobiose family IIC component 12 425 4.7E-116 T 28-03-2018 IPR004501 Phosphotransferase system, EIIC component, type 3 GO:0008982|GO:0009401|GO:0016021 ALX04_RS00455 02ac2d582a9c6a573b1460eb6e031662 178 Gene3D G3DSA:3.90.930.12 2 82 2.0E-28 T 28-03-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 ALX04_RS00455 02ac2d582a9c6a573b1460eb6e031662 178 SUPERFAMILY SSF56053 83 177 3.14E-36 T 28-03-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 ALX04_RS00455 02ac2d582a9c6a573b1460eb6e031662 178 Hamap MF_01365_B 50S ribosomal protein L6 [rplF]. 1 176 37.645 T 28-03-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 ALX04_RS00455 02ac2d582a9c6a573b1460eb6e031662 178 PRINTS PR00059 Ribosomal protein L6 signature 71 96 9.8E-34 T 28-03-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 ALX04_RS00455 02ac2d582a9c6a573b1460eb6e031662 178 PRINTS PR00059 Ribosomal protein L6 signature 99 115 9.8E-34 T 28-03-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 ALX04_RS00455 02ac2d582a9c6a573b1460eb6e031662 178 PRINTS PR00059 Ribosomal protein L6 signature 141 162 9.8E-34 T 28-03-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 ALX04_RS00455 02ac2d582a9c6a573b1460eb6e031662 178 ProSitePatterns PS00525 Ribosomal protein L6 signature 1. 154 162 - T 28-03-2018 IPR002358 Ribosomal protein L6, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 ALX04_RS00455 02ac2d582a9c6a573b1460eb6e031662 178 PIRSF PIRSF002162 1 177 4.1E-46 T 28-03-2018 IPR000702 Ribosomal protein L6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 ALX04_RS00455 02ac2d582a9c6a573b1460eb6e031662 178 TIGRFAM TIGR03654 L6_bact: ribosomal protein uL6 2 176 1.3E-76 T 28-03-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 ALX04_RS00455 02ac2d582a9c6a573b1460eb6e031662 178 Gene3D G3DSA:3.90.930.12 83 178 5.4E-40 T 28-03-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 ALX04_RS00455 02ac2d582a9c6a573b1460eb6e031662 178 SUPERFAMILY SSF56053 2 82 5.76E-26 T 28-03-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 ALX04_RS00455 02ac2d582a9c6a573b1460eb6e031662 178 Pfam PF00347 Ribosomal protein L6 12 82 1.1E-20 T 28-03-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 ALX04_RS00455 02ac2d582a9c6a573b1460eb6e031662 178 Pfam PF00347 Ribosomal protein L6 90 164 2.9E-19 T 28-03-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 ALX04_RS15510 f354e4b89d2b9625c0c759f5d913b881 445 Gene3D G3DSA:3.50.50.60 1 154 1.8E-12 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ALX04_RS15510 f354e4b89d2b9625c0c759f5d913b881 445 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 338 435 3.3E-6 T 28-03-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 ALX04_RS15510 f354e4b89d2b9625c0c759f5d913b881 445 Gene3D G3DSA:3.40.50.720 158 327 1.6E-28 T 28-03-2018 ALX04_RS15510 f354e4b89d2b9625c0c759f5d913b881 445 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 5 316 2.2E-50 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ALX04_RS15510 f354e4b89d2b9625c0c759f5d913b881 445 SUPERFAMILY SSF55424 333 438 2.23E-11 T 28-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 ALX04_RS15510 f354e4b89d2b9625c0c759f5d913b881 445 Gene3D G3DSA:3.30.390.30 328 445 4.5E-11 T 28-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 ALX04_RS15510 f354e4b89d2b9625c0c759f5d913b881 445 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 294 301 3.7E-31 T 28-03-2018 ALX04_RS15510 f354e4b89d2b9625c0c759f5d913b881 445 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 132 141 3.7E-31 T 28-03-2018 ALX04_RS15510 f354e4b89d2b9625c0c759f5d913b881 445 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 37 52 3.7E-31 T 28-03-2018 ALX04_RS15510 f354e4b89d2b9625c0c759f5d913b881 445 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 252 266 3.7E-31 T 28-03-2018 ALX04_RS15510 f354e4b89d2b9625c0c759f5d913b881 445 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 332 353 3.7E-31 T 28-03-2018 ALX04_RS15510 f354e4b89d2b9625c0c759f5d913b881 445 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 5 27 3.7E-31 T 28-03-2018 ALX04_RS15510 f354e4b89d2b9625c0c759f5d913b881 445 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 166 191 3.7E-31 T 28-03-2018 ALX04_RS15510 f354e4b89d2b9625c0c759f5d913b881 445 SUPERFAMILY SSF51905 4 357 2.33E-42 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ALX04_RS15510 f354e4b89d2b9625c0c759f5d913b881 445 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 6 25 9.6E-23 T 28-03-2018 ALX04_RS15510 f354e4b89d2b9625c0c759f5d913b881 445 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 166 184 9.6E-23 T 28-03-2018 ALX04_RS15510 f354e4b89d2b9625c0c759f5d913b881 445 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 251 267 9.6E-23 T 28-03-2018 ALX04_RS15510 f354e4b89d2b9625c0c759f5d913b881 445 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 129 147 9.6E-23 T 28-03-2018 ALX04_RS15510 f354e4b89d2b9625c0c759f5d913b881 445 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 279 301 9.6E-23 T 28-03-2018 ALX04_RS05965 d506da67d40f08972cd88dfe2623fd38 172 SUPERFAMILY SSF56300 1 168 2.73E-42 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like ALX04_RS05965 d506da67d40f08972cd88dfe2623fd38 172 TIGRFAM TIGR00040 yfcE: phosphodiesterase, MJ0936 family 1 147 2.6E-21 T 28-03-2018 IPR000979 Phosphodiesterase MJ0936/Vps29 Reactome: R-HSA-3238698 ALX04_RS05965 d506da67d40f08972cd88dfe2623fd38 172 Gene3D G3DSA:3.60.21.10 1 172 1.3E-20 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like ALX04_RS05965 d506da67d40f08972cd88dfe2623fd38 172 Pfam PF12850 Calcineurin-like phosphoesterase superfamily domain 1 147 1.3E-29 T 28-03-2018 IPR024654 Calcineurin-like phosphoesterase domain, lpxH type Reactome: R-HSA-3238698 ALX04_RS13630 6451395700178c283ebcd8a706d9159b 423 Gene3D G3DSA:1.10.287.40 1 105 3.3E-22 T 28-03-2018 ALX04_RS13630 6451395700178c283ebcd8a706d9159b 423 TIGRFAM TIGR00414 serS: serine--tRNA ligase 1 416 2.1E-167 T 28-03-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 ALX04_RS13630 6451395700178c283ebcd8a706d9159b 423 SUPERFAMILY SSF46589 1 113 2.62E-26 T 28-03-2018 IPR010978 tRNA-binding arm GO:0000166 ALX04_RS13630 6451395700178c283ebcd8a706d9159b 423 PRINTS PR00981 Seryl-tRNA synthetase signature 333 349 1.3E-29 T 28-03-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 ALX04_RS13630 6451395700178c283ebcd8a706d9159b 423 PRINTS PR00981 Seryl-tRNA synthetase signature 264 276 1.3E-29 T 28-03-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 ALX04_RS13630 6451395700178c283ebcd8a706d9159b 423 PRINTS PR00981 Seryl-tRNA synthetase signature 351 367 1.3E-29 T 28-03-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 ALX04_RS13630 6451395700178c283ebcd8a706d9159b 423 PRINTS PR00981 Seryl-tRNA synthetase signature 316 329 1.3E-29 T 28-03-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 ALX04_RS13630 6451395700178c283ebcd8a706d9159b 423 PRINTS PR00981 Seryl-tRNA synthetase signature 276 289 1.3E-29 T 28-03-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 ALX04_RS13630 6451395700178c283ebcd8a706d9159b 423 Hamap MF_00176 Serine--tRNA ligase [serS]. 1 421 41.505 T 28-03-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 ALX04_RS13630 6451395700178c283ebcd8a706d9159b 423 SUPERFAMILY SSF55681 117 417 1.07E-102 T 28-03-2018 ALX04_RS13630 6451395700178c283ebcd8a706d9159b 423 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 223 399 2.9E-36 T 28-03-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 ALX04_RS13630 6451395700178c283ebcd8a706d9159b 423 PIRSF PIRSF001529 1 423 1.0E-176 T 28-03-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 ALX04_RS13630 6451395700178c283ebcd8a706d9159b 423 Gene3D G3DSA:3.30.930.10 106 423 8.0E-96 T 28-03-2018 ALX04_RS13630 6451395700178c283ebcd8a706d9159b 423 Pfam PF02403 Seryl-tRNA synthetase N-terminal domain 1 108 2.9E-28 T 28-03-2018 IPR015866 Serine-tRNA synthetase, type1, N-terminal KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281|Reactome: R-HSA-2408557|Reactome: R-HSA-379716 ALX04_RS11155 3e848c03ac70c752c403f736d7705055 486 Pfam PF00232 Glycosyl hydrolase family 1 8 482 8.2E-130 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 ALX04_RS11155 3e848c03ac70c752c403f736d7705055 486 PRINTS PR00131 Glycosyl hydrolase family 1 signature 380 388 2.3E-16 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 ALX04_RS11155 3e848c03ac70c752c403f736d7705055 486 PRINTS PR00131 Glycosyl hydrolase family 1 signature 447 459 2.3E-16 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 ALX04_RS11155 3e848c03ac70c752c403f736d7705055 486 PRINTS PR00131 Glycosyl hydrolase family 1 signature 316 330 2.3E-16 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 ALX04_RS11155 3e848c03ac70c752c403f736d7705055 486 PRINTS PR00131 Glycosyl hydrolase family 1 signature 401 412 2.3E-16 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 ALX04_RS11155 3e848c03ac70c752c403f736d7705055 486 PRINTS PR00131 Glycosyl hydrolase family 1 signature 422 439 2.3E-16 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 ALX04_RS11155 3e848c03ac70c752c403f736d7705055 486 ProSitePatterns PS00653 Glycosyl hydrolases family 1 N-terminal signature. 14 28 - T 28-03-2018 IPR033132 Glycosyl hydrolases family 1, N-terminal conserved site ALX04_RS11155 3e848c03ac70c752c403f736d7705055 486 ProSitePatterns PS00572 Glycosyl hydrolases family 1 active site. 380 388 - T 28-03-2018 IPR018120 Glycoside hydrolase family 1, active site ALX04_RS11155 3e848c03ac70c752c403f736d7705055 486 Gene3D G3DSA:3.20.20.80 2 486 6.8E-150 T 28-03-2018 ALX04_RS11155 3e848c03ac70c752c403f736d7705055 486 SUPERFAMILY SSF51445 8 483 7.05E-156 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily ALX04_RS02150 5d0b82d54eea5a7dba53991592e8c8fa 187 Gene3D G3DSA:2.60.40.200 12 168 2.1E-4 T 28-03-2018 IPR001424 Superoxide dismutase, copper/zinc binding domain GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 ALX04_RS15175 df61bf6c8bd042fba0c400f012266bbf 483 Pfam PF02378 Phosphotransferase system, EIIC 122 406 1.2E-26 T 28-03-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 ALX04_RS15175 df61bf6c8bd042fba0c400f012266bbf 483 ProSitePatterns PS01035 PTS EIIB domains cysteine phosphorylation site signature. 24 41 - T 28-03-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 ALX04_RS15175 df61bf6c8bd042fba0c400f012266bbf 483 Pfam PF00367 phosphotransferase system, EIIB 15 43 1.8E-15 T 28-03-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 ALX04_RS15175 df61bf6c8bd042fba0c400f012266bbf 483 Gene3D G3DSA:3.30.1360.60 7 81 9.7E-27 T 28-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 ALX04_RS15175 df61bf6c8bd042fba0c400f012266bbf 483 SUPERFAMILY SSF55604 11 84 4.58E-21 T 28-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 ALX04_RS07785 503e3975358cb852651470e3fe61392e 174 SUPERFAMILY SSF55729 5 166 1.17E-21 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase ALX04_RS07785 503e3975358cb852651470e3fe61392e 174 Gene3D G3DSA:3.40.630.30 4 174 3.1E-21 T 28-03-2018 ALX04_RS15415 45bd4ead467408da939bf922aea4d0fb 32 Gene3D G3DSA:3.10.20.320 1 32 4.2E-6 T 28-03-2018 ALX04_RS15415 45bd4ead467408da939bf922aea4d0fb 32 Pfam PF06458 MucBP domain 3 32 9.1E-7 T 28-03-2018 IPR009459 MucBP domain ALX04_RS09695 7c3e3279374467b78cf83d65e58e82ee 421 Pfam PF05656 Protein of unknown function (DUF805) 68 180 1.6E-16 T 28-03-2018 IPR008523 Protein of unknown function DUF805 GO:0016021 ALX04_RS09695 7c3e3279374467b78cf83d65e58e82ee 421 Pfam PF11611 Domain of unknown function (DUF4352) 295 385 6.5E-6 T 28-03-2018 IPR029051 Domain of unknown function DUF4352 ALX04_RS09695 7c3e3279374467b78cf83d65e58e82ee 421 Pfam PF13240 zinc-ribbon domain 6 27 1.4E-7 T 28-03-2018 IPR026870 Zinc-ribbon domain Reactome: R-HSA-202670 ALX04_RS09695 7c3e3279374467b78cf83d65e58e82ee 421 Gene3D G3DSA:2.60.40.1240 263 421 1.7E-11 T 28-03-2018 IPR029050 Immunoprotective extracellular, immunoglobulin-like domain ALX04_RS08350 be1f366f964c47db376cdacb2c16012d 167 Pfam PF07274 Protein of unknown function (DUF1440) 20 153 6.3E-54 T 28-03-2018 IPR009898 Protein of unknown function DUF1440 ALX04_RS08350 be1f366f964c47db376cdacb2c16012d 167 Gene3D G3DSA:2.60.120.180 15 160 2.6E-4 T 28-03-2018 IPR013319 Glycoside hydrolase family 11/12 GO:0004553 MetaCyc: PWY-6784 ALX04_RS06685 8c14b771958872b3ddad61de5a795e0e 447 Pfam PF17288 Terminase RNAseH like domain 277 436 1.8E-27 T 28-03-2018 IPR035413 Phage terminase large subunit, C-terminal ALX04_RS06685 8c14b771958872b3ddad61de5a795e0e 447 Pfam PF04466 Phage terminase large subunit 35 243 2.6E-35 T 28-03-2018 IPR035412 Phage terminase large subunit, N-terminal ALX04_RS06685 8c14b771958872b3ddad61de5a795e0e 447 TIGRFAM TIGR01547 phage_term_2: phage terminase, large subunit, PBSX family 35 441 2.9E-69 T 28-03-2018 IPR006437 Bacteriophage terminase, large subunit GO:0006323 ALX04_RS04455 f55ca2842702a564e9fab6ebd4659b6f 250 Pfam PF04452 RNA methyltransferase 19 244 2.0E-59 T 28-03-2018 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 ALX04_RS04455 f55ca2842702a564e9fab6ebd4659b6f 250 SUPERFAMILY SSF75217 74 248 7.85E-46 T 28-03-2018 IPR029028 Alpha/beta knot methyltransferases ALX04_RS04455 f55ca2842702a564e9fab6ebd4659b6f 250 SUPERFAMILY SSF88697 2 70 5.72E-11 T 28-03-2018 IPR015947 PUA-like domain ALX04_RS04455 f55ca2842702a564e9fab6ebd4659b6f 250 PIRSF PIRSF015601 1 249 1.5E-51 T 28-03-2018 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 ALX04_RS04455 f55ca2842702a564e9fab6ebd4659b6f 250 TIGRFAM TIGR00046 TIGR00046: RNA methyltransferase, RsmE family 14 244 1.6E-44 T 28-03-2018 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 ALX04_RS04455 f55ca2842702a564e9fab6ebd4659b6f 250 Gene3D G3DSA:3.40.1280.10 1 250 1.3E-64 T 28-03-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal ALX04_RS00475 5350e87ae1723d85ddc8bedb6434fd71 143 Pfam PF00828 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A 27 141 1.5E-37 T 28-03-2018 IPR021131 Ribosomal protein L18e/L15P ALX04_RS00475 5350e87ae1723d85ddc8bedb6434fd71 143 TIGRFAM TIGR01071 rplO_bact: ribosomal protein uL15 2 140 4.2E-54 T 28-03-2018 IPR005749 Ribosomal protein L15, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 ALX04_RS00475 5350e87ae1723d85ddc8bedb6434fd71 143 Gene3D G3DSA:3.100.10.10 36 143 4.4E-34 T 28-03-2018 ALX04_RS00475 5350e87ae1723d85ddc8bedb6434fd71 143 Hamap MF_01341 50S ribosomal protein L15 [rplO]. 3 143 22.0 T 28-03-2018 IPR030878 Ribosomal protein L15 GO:0003735|GO:0006412|GO:0015934 ALX04_RS00475 5350e87ae1723d85ddc8bedb6434fd71 143 SUPERFAMILY SSF52080 5 142 3.66E-47 T 28-03-2018 IPR021131 Ribosomal protein L18e/L15P ALX04_RS00475 5350e87ae1723d85ddc8bedb6434fd71 143 ProSitePatterns PS00475 Ribosomal protein L15 signature. 107 137 - T 28-03-2018 IPR001196 Ribosomal protein L15, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 ALX04_RS13345 41af409b840b729ebed6e232ef8460dd 59 TIGRFAM TIGR03949 bact_IIb_cerein: class IIb bacteriocin, lactobin A/cerein 7B family 8 36 3.0E-6 T 28-03-2018 IPR023991 Bacteriocin, class IIb, lactobin A/cerein 7B family ALX04_RS12560 00779f30cb720e88647dd502476d8626 612 Gene3D G3DSA:3.40.50.2300 516 612 6.9E-9 T 28-03-2018 ALX04_RS12560 00779f30cb720e88647dd502476d8626 612 Pfam PF02378 Phosphotransferase system, EIIC 34 294 9.3E-16 T 28-03-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 ALX04_RS12560 00779f30cb720e88647dd502476d8626 612 SUPERFAMILY SSF52794 525 611 9.81E-11 T 28-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 ALX04_RS12560 00779f30cb720e88647dd502476d8626 612 SUPERFAMILY SSF52794 401 488 7.85E-21 T 28-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 ALX04_RS12560 00779f30cb720e88647dd502476d8626 612 Pfam PF02302 PTS system, Lactose/Cellobiose specific IIB subunit 402 484 2.3E-7 T 28-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 ALX04_RS12560 00779f30cb720e88647dd502476d8626 612 Gene3D G3DSA:3.40.50.2300 397 490 3.1E-14 T 28-03-2018 ALX04_RS12560 00779f30cb720e88647dd502476d8626 612 TIGRFAM TIGR00851 mtlA: PTS system, mannitol-specific IIC component 25 366 1.6E-154 T 28-03-2018 IPR004718 Phosphotransferase system, mannitol-specific enzyme IIC GO:0008982|GO:0009401|GO:0016021 KEGG: 00051+2.7.1.197|KEGG: 00710+2.7.1.19|MetaCyc: PWY-5723 ALX04_RS02180 dc672d27d4494041452536b534bfb08a 348 Pfam PF06030 Bacterial protein of unknown function (DUF916) 35 157 9.6E-31 T 28-03-2018 IPR010317 Protein of unknown function DUF916, cell surface putative ALX04_RS02180 dc672d27d4494041452536b534bfb08a 348 Gene3D G3DSA:2.60.40.10 164 290 0.76 T 28-03-2018 IPR013783 Immunoglobulin-like fold ALX04_RS02180 dc672d27d4494041452536b534bfb08a 348 Pfam PF11797 Protein of unknown function C-terminal (DUF3324) 167 307 1.5E-44 T 28-03-2018 IPR021759 Domain of unknown function DUF3324, C-terminal ALX04_RS02180 dc672d27d4494041452536b534bfb08a 348 Gene3D G3DSA:2.60.40.1710 43 163 1.8E-6 T 28-03-2018 ALX04_RS14890 86a91a0ca85513daf8138db8f49977f8 325 Pfam PF07949 YbbR-like protein 58 137 1.9E-8 T 28-03-2018 IPR012505 YbbR-like ALX04_RS14890 86a91a0ca85513daf8138db8f49977f8 325 Pfam PF07949 YbbR-like protein 153 230 4.8E-7 T 28-03-2018 IPR012505 YbbR-like ALX04_RS14890 86a91a0ca85513daf8138db8f49977f8 325 Pfam PF07949 YbbR-like protein 241 320 4.6E-7 T 28-03-2018 IPR012505 YbbR-like ALX04_RS01095 f0aca434093dcc503169de617c381e44 198 Pfam PF00589 Phage integrase family 15 170 7.2E-27 T 28-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 ALX04_RS01095 f0aca434093dcc503169de617c381e44 198 SUPERFAMILY SSF56349 14 178 2.18E-34 T 28-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 ALX04_RS01095 f0aca434093dcc503169de617c381e44 198 Gene3D G3DSA:1.10.443.10 9 174 8.2E-33 T 28-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 ALX04_RS00255 fdb853b69bb40389d1345383047f4ba7 264 Pfam PF07859 alpha/beta hydrolase fold 81 232 3.5E-6 T 28-03-2018 IPR013094 Alpha/beta hydrolase fold-3 GO:0008152|GO:0016787 ALX04_RS00255 fdb853b69bb40389d1345383047f4ba7 264 SUPERFAMILY SSF53474 14 263 8.39E-30 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold ALX04_RS00255 fdb853b69bb40389d1345383047f4ba7 264 Gene3D G3DSA:3.40.50.1820 1 264 7.7E-37 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold ALX04_RS05530 745fea820fdf6de3ed27ed6a96a615b9 459 TIGRFAM TIGR01087 murD: UDP-N-acetylmuramoylalanine--D-glutamate ligase 11 450 8.6E-127 T 28-03-2018 IPR005762 UDP-N-acetylmuramoylalanine-D-glutamate ligase GO:0005524|GO:0005737|GO:0008360|GO:0008764|GO:0051301 KEGG: 00471+6.3.2.9|KEGG: 00550+6.3.2.9|MetaCyc: PWY-6386|MetaCyc: PWY-6387 ALX04_RS05530 745fea820fdf6de3ed27ed6a96a615b9 459 Gene3D G3DSA:3.90.190.20 317 451 1.6E-33 T 28-03-2018 ALX04_RS05530 745fea820fdf6de3ed27ed6a96a615b9 459 ProSitePatterns PS01011 Folylpolyglutamate synthase signature 1. 115 138 - T 28-03-2018 IPR018109 Folylpolyglutamate synthetase, conserved site GO:0004326|GO:0005524|GO:0009396 Reactome: R-HSA-196757 ALX04_RS05530 745fea820fdf6de3ed27ed6a96a615b9 459 Gene3D G3DSA:3.40.1190.10 102 310 1.2E-51 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 ALX04_RS05530 745fea820fdf6de3ed27ed6a96a615b9 459 Gene3D G3DSA:3.40.50.720 1 101 5.0E-16 T 28-03-2018 ALX04_RS05530 745fea820fdf6de3ed27ed6a96a615b9 459 SUPERFAMILY SSF53623 105 310 2.49E-50 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 ALX04_RS05530 745fea820fdf6de3ed27ed6a96a615b9 459 SUPERFAMILY SSF51984 10 100 1.05E-16 T 28-03-2018 ALX04_RS05530 745fea820fdf6de3ed27ed6a96a615b9 459 Hamap MF_00639 UDP-N-acetylmuramoylalanine--D-glutamate ligase [murD]. 10 452 34.877 T 28-03-2018 IPR005762 UDP-N-acetylmuramoylalanine-D-glutamate ligase GO:0005524|GO:0005737|GO:0008360|GO:0008764|GO:0051301 KEGG: 00471+6.3.2.9|KEGG: 00550+6.3.2.9|MetaCyc: PWY-6386|MetaCyc: PWY-6387 ALX04_RS05530 745fea820fdf6de3ed27ed6a96a615b9 459 Pfam PF08245 Mur ligase middle domain 117 293 5.8E-39 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 ALX04_RS05530 745fea820fdf6de3ed27ed6a96a615b9 459 SUPERFAMILY SSF53244 312 452 1.22E-41 T 28-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 ALX04_RS05530 745fea820fdf6de3ed27ed6a96a615b9 459 Pfam PF02875 Mur ligase family, glutamate ligase domain 313 383 6.0E-9 T 28-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 ALX04_RS00850 3d6393530ee5ac371876a4e0294d1e41 182 Pfam PF10035 Uncharacterized protein conserved in bacteria (DUF2179) 113 165 2.4E-5 T 28-03-2018 IPR019264 Domain of unknown function DUF2179 ALX04_RS00850 3d6393530ee5ac371876a4e0294d1e41 182 Hamap MF_01515 UPF0316 protein . 5 173 30.917 T 28-03-2018 IPR022930 Protein of unknown function UPF0316 ALX04_RS00700 1dccb2d3217951d8bf201ef000c9c06d 512 SUPERFAMILY SSF100950 244 509 1.01E-58 T 28-03-2018 ALX04_RS00700 1dccb2d3217951d8bf201ef000c9c06d 512 PIRSF PIRSF009451 1 512 1.2E-236 T 28-03-2018 IPR006472 Citrate lyase, alpha subunit GO:0005737|GO:0006084|GO:0008814|GO:0009346 MetaCyc: PWY-6038 ALX04_RS00700 1dccb2d3217951d8bf201ef000c9c06d 512 Gene3D G3DSA:3.40.1080.10 243 486 1.3E-37 T 28-03-2018 ALX04_RS00700 1dccb2d3217951d8bf201ef000c9c06d 512 SUPERFAMILY SSF100950 3 241 1.65E-71 T 28-03-2018 ALX04_RS00700 1dccb2d3217951d8bf201ef000c9c06d 512 Pfam PF04223 Citrate lyase, alpha subunit (CitF) 45 510 9.4E-235 T 28-03-2018 IPR006472 Citrate lyase, alpha subunit GO:0005737|GO:0006084|GO:0008814|GO:0009346 MetaCyc: PWY-6038 ALX04_RS00700 1dccb2d3217951d8bf201ef000c9c06d 512 Gene3D G3DSA:3.40.1080.10 1 241 4.7E-51 T 28-03-2018 ALX04_RS00700 1dccb2d3217951d8bf201ef000c9c06d 512 TIGRFAM TIGR01584 citF: citrate lyase, alpha subunit 26 512 6.0E-244 T 28-03-2018 IPR006472 Citrate lyase, alpha subunit GO:0005737|GO:0006084|GO:0008814|GO:0009346 MetaCyc: PWY-6038 ALX04_RS02015 dfde672488b15618014a6b5e12f6fc17 709 SUPERFAMILY SSF53955 76 288 2.7E-66 T 28-03-2018 IPR023346 Lysozyme-like domain ALX04_RS02015 dfde672488b15618014a6b5e12f6fc17 709 Gene3D G3DSA:3.40.710.10 285 702 7.9E-92 T 28-03-2018 ALX04_RS02015 dfde672488b15618014a6b5e12f6fc17 709 Pfam PF00905 Penicillin binding protein transpeptidase domain 362 610 1.3E-34 T 28-03-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 ALX04_RS02015 dfde672488b15618014a6b5e12f6fc17 709 TIGRFAM TIGR02074 PBP_1a_fam: penicillin-binding protein, 1A family 98 646 1.9E-172 T 28-03-2018 ALX04_RS02015 dfde672488b15618014a6b5e12f6fc17 709 Pfam PF00912 Transglycosylase 91 266 6.9E-58 T 28-03-2018 IPR001264 Glycosyl transferase, family 51 ALX04_RS02015 dfde672488b15618014a6b5e12f6fc17 709 Gene3D G3DSA:1.10.3810.10 79 283 1.1E-69 T 28-03-2018 IPR001264 Glycosyl transferase, family 51 ALX04_RS02015 dfde672488b15618014a6b5e12f6fc17 709 SUPERFAMILY SSF56601 300 651 3.7E-102 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like ALX04_RS02015 dfde672488b15618014a6b5e12f6fc17 709 SUPERFAMILY SSF56601 248 270 3.7E-102 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like ALX04_RS07750 ec5f2df2678ad161a2f724a9c983599b 455 Pfam PF00392 Bacterial regulatory proteins, gntR family 15 72 8.5E-7 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 ALX04_RS07750 ec5f2df2678ad161a2f724a9c983599b 455 Gene3D G3DSA:3.40.640.10 115 359 1.5E-32 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 ALX04_RS07750 ec5f2df2678ad161a2f724a9c983599b 455 Pfam PF00155 Aminotransferase class I and II 121 412 1.2E-13 T 28-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 ALX04_RS07750 ec5f2df2678ad161a2f724a9c983599b 455 Gene3D G3DSA:1.10.10.10 1 86 1.1E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS07750 ec5f2df2678ad161a2f724a9c983599b 455 SUPERFAMILY SSF53383 67 453 2.07E-67 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase ALX04_RS07750 ec5f2df2678ad161a2f724a9c983599b 455 Gene3D G3DSA:3.90.1150.10 360 454 6.2E-13 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 ALX04_RS07750 ec5f2df2678ad161a2f724a9c983599b 455 SUPERFAMILY SSF46785 5 82 8.78E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS07750 ec5f2df2678ad161a2f724a9c983599b 455 SMART SM00345 16 73 1.1E-5 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 ALX04_RS06230 b8c2fa7407fad57c4ca222b2b5ff86f2 573 Hamap MF_00728 Septation ring formation regulator EzrA [ezrA]. 1 563 22.72 T 28-03-2018 IPR010379 Septation ring formation regulator EzrA GO:0000921|GO:0005940|GO:0016021 ALX04_RS06230 b8c2fa7407fad57c4ca222b2b5ff86f2 573 Gene3D G3DSA:3.90.20.10 218 416 0.012 T 28-03-2018 ALX04_RS06230 b8c2fa7407fad57c4ca222b2b5ff86f2 573 Gene3D G3DSA:1.20.5.320 446 526 0.1 T 28-03-2018 ALX04_RS06230 b8c2fa7407fad57c4ca222b2b5ff86f2 573 Gene3D G3DSA:3.90.20.10 15 215 0.0077 T 28-03-2018 ALX04_RS06230 b8c2fa7407fad57c4ca222b2b5ff86f2 573 Pfam PF06160 Septation ring formation regulator, EzrA 4 560 8.4E-170 T 28-03-2018 IPR010379 Septation ring formation regulator EzrA GO:0000921|GO:0005940|GO:0016021 ALX04_RS11440 310c6a8ea28351b79df80518cf6807d4 621 Gene3D G3DSA:1.10.10.10 83 151 5.9E-13 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS11440 310c6a8ea28351b79df80518cf6807d4 621 Gene3D G3DSA:1.10.10.10 1 55 6.5E-6 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS11440 310c6a8ea28351b79df80518cf6807d4 621 Gene3D G3DSA:1.10.1790.10 274 377 3.4E-11 T 28-03-2018 IPR011608 PRD domain GO:0006355 ALX04_RS11440 310c6a8ea28351b79df80518cf6807d4 621 Gene3D G3DSA:3.40.930.10 474 620 1.5E-20 T 28-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 ALX04_RS11440 310c6a8ea28351b79df80518cf6807d4 621 SUPERFAMILY SSF55804 489 618 4.32E-21 T 28-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 ALX04_RS11440 310c6a8ea28351b79df80518cf6807d4 621 Pfam PF00874 PRD domain 289 371 1.2E-8 T 28-03-2018 IPR011608 PRD domain GO:0006355 ALX04_RS11440 310c6a8ea28351b79df80518cf6807d4 621 SUPERFAMILY SSF63520 278 372 3.27E-13 T 28-03-2018 IPR011608 PRD domain GO:0006355 ALX04_RS11440 310c6a8ea28351b79df80518cf6807d4 621 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 498 617 5.0E-14 T 28-03-2018 IPR002178 PTS EIIA type-2 domain ALX04_RS11440 310c6a8ea28351b79df80518cf6807d4 621 Pfam PF08279 HTH domain 88 146 3.0E-9 T 28-03-2018 IPR013196 Helix-turn-helix, type 11 ALX04_RS11440 310c6a8ea28351b79df80518cf6807d4 621 Pfam PF08279 HTH domain 6 48 6.0E-5 T 28-03-2018 IPR013196 Helix-turn-helix, type 11 ALX04_RS10235 638f2dc04f5d85e1f3b9b02ac0f26cd8 474 Pfam PF13520 Amino acid permease 31 436 1.8E-57 T 28-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 ALX04_RS10235 638f2dc04f5d85e1f3b9b02ac0f26cd8 474 PIRSF PIRSF006060 3 474 5.0E-91 T 28-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 ALX04_RS10235 638f2dc04f5d85e1f3b9b02ac0f26cd8 474 Gene3D G3DSA:1.20.1510.10 34 442 0.0096 T 28-03-2018 ALX04_RS15745 c79f2521cb6a9356499151ea9bfbdf5e 196 Gene3D G3DSA:1.10.443.10 13 190 6.9E-26 T 28-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 ALX04_RS15745 c79f2521cb6a9356499151ea9bfbdf5e 196 SUPERFAMILY SSF56349 8 194 8.54E-34 T 28-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 ALX04_RS15745 c79f2521cb6a9356499151ea9bfbdf5e 196 Pfam PF00589 Phage integrase family 29 180 6.7E-17 T 28-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 ALX04_RS06105 c410d5f87d26ae0b8af9a005a8de55ab 380 TIGRFAM TIGR02012 tigrfam_recA: protein RecA 5 324 1.4E-169 T 28-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 ALX04_RS06105 c410d5f87d26ae0b8af9a005a8de55ab 380 SUPERFAMILY SSF52540 4 267 8.52E-65 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase ALX04_RS06105 c410d5f87d26ae0b8af9a005a8de55ab 380 Gene3D G3DSA:3.40.50.300 26 268 3.9E-47 T 28-03-2018 ALX04_RS06105 c410d5f87d26ae0b8af9a005a8de55ab 380 Gene3D G3DSA:3.30.250.10 269 326 9.9E-26 T 28-03-2018 IPR023400 DNA recombination and repair protein RecA, C-terminal ALX04_RS06105 c410d5f87d26ae0b8af9a005a8de55ab 380 ProSitePatterns PS00321 recA signature. 213 221 - T 28-03-2018 IPR020584 DNA recombination/repair protein RecA, conserved site GO:0003677|GO:0005524|GO:0006259|GO:0008094 ALX04_RS06105 c410d5f87d26ae0b8af9a005a8de55ab 380 SMART SM00382 57 228 4.6E-11 T 28-03-2018 IPR003593 AAA+ ATPase domain ALX04_RS06105 c410d5f87d26ae0b8af9a005a8de55ab 380 SUPERFAMILY SSF54752 268 327 3.01E-22 T 28-03-2018 IPR023400 DNA recombination and repair protein RecA, C-terminal ALX04_RS06105 c410d5f87d26ae0b8af9a005a8de55ab 380 Pfam PF00154 recA bacterial DNA recombination protein 8 268 4.2E-140 T 28-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 ALX04_RS06105 c410d5f87d26ae0b8af9a005a8de55ab 380 Hamap MF_00268 Protein RecA [recA]. 5 329 52.609 T 28-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 ALX04_RS06105 c410d5f87d26ae0b8af9a005a8de55ab 380 PRINTS PR00142 RecA protein signature 297 314 3.4E-85 T 28-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 ALX04_RS06105 c410d5f87d26ae0b8af9a005a8de55ab 380 PRINTS PR00142 RecA protein signature 93 122 3.4E-85 T 28-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 ALX04_RS06105 c410d5f87d26ae0b8af9a005a8de55ab 380 PRINTS PR00142 RecA protein signature 127 156 3.4E-85 T 28-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 ALX04_RS06105 c410d5f87d26ae0b8af9a005a8de55ab 380 PRINTS PR00142 RecA protein signature 165 194 3.4E-85 T 28-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 ALX04_RS06105 c410d5f87d26ae0b8af9a005a8de55ab 380 PRINTS PR00142 RecA protein signature 243 272 3.4E-85 T 28-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 ALX04_RS06105 c410d5f87d26ae0b8af9a005a8de55ab 380 PRINTS PR00142 RecA protein signature 210 238 3.4E-85 T 28-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 ALX04_RS02075 f0a70afcd940407e4ce67c5c20b442c3 45 TIGRFAM TIGR01167 LPXTG_anchor: LPXTG cell wall anchor domain 14 42 1.8E-4 T 28-03-2018 ALX04_RS02075 f0a70afcd940407e4ce67c5c20b442c3 45 Pfam PF00746 LPXTG cell wall anchor motif 8 41 7.6E-5 T 28-03-2018 IPR019948 Gram-positive LPXTG cell wall anchor ALX04_RS05835 96e947f927a08a487d8429783cab57ec 209 PIRSF PIRSF012565 1 209 2.4E-64 T 28-03-2018 IPR009370 Protein of unknown function DUF1027 ALX04_RS05835 96e947f927a08a487d8429783cab57ec 209 Pfam PF06265 Protein of unknown function (DUF1027) 33 116 1.4E-34 T 28-03-2018 IPR009370 Protein of unknown function DUF1027 ALX04_RS06300 5f200489383575c6440fbc79c90c87e7 426 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 42 149 7.0E-17 T 28-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 ALX04_RS06300 5f200489383575c6440fbc79c90c87e7 426 Pfam PF12002 MgsA AAA+ ATPase C terminal 253 418 1.2E-63 T 28-03-2018 IPR021886 MgsA AAA+ ATPase C-terminal ALX04_RS06300 5f200489383575c6440fbc79c90c87e7 426 Gene3D G3DSA:1.10.3710.10 333 426 1.1E-26 T 28-03-2018 ALX04_RS06300 5f200489383575c6440fbc79c90c87e7 426 SUPERFAMILY SSF52540 3 208 2.25E-40 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase ALX04_RS06300 5f200489383575c6440fbc79c90c87e7 426 SMART SM00382 38 150 1.2E-13 T 28-03-2018 IPR003593 AAA+ ATPase domain ALX04_RS06300 5f200489383575c6440fbc79c90c87e7 426 SUPERFAMILY SSF48019 238 420 1.3E-68 T 28-03-2018 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 ALX04_RS06300 5f200489383575c6440fbc79c90c87e7 426 Gene3D G3DSA:1.20.272.10 237 330 1.2E-36 T 28-03-2018 ALX04_RS06300 5f200489383575c6440fbc79c90c87e7 426 Gene3D G3DSA:1.10.8.60 138 228 4.3E-18 T 28-03-2018 ALX04_RS06300 5f200489383575c6440fbc79c90c87e7 426 Gene3D G3DSA:3.40.50.300 1 137 3.0E-28 T 28-03-2018 ALX04_RS06300 5f200489383575c6440fbc79c90c87e7 426 Pfam PF16193 AAA C-terminal domain 173 252 4.2E-25 T 28-03-2018 IPR032423 AAA C-terminal domain ALX04_RS03465 7c7d013c06b54833af652131f687b378 152 Gene3D G3DSA:3.40.630.30 1 150 4.1E-16 T 28-03-2018 ALX04_RS03465 7c7d013c06b54833af652131f687b378 152 SUPERFAMILY SSF55729 1 142 6.13E-19 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase ALX04_RS03465 7c7d013c06b54833af652131f687b378 152 Pfam PF13673 Acetyltransferase (GNAT) domain 32 136 2.8E-7 T 28-03-2018 IPR000182 GNAT domain GO:0008080 ALX04_RS15535 56e46f6441519e044e9ddf879e3b809a 140 Gene3D G3DSA:3.30.300.20 1 139 2.8E-16 T 28-03-2018 IPR015946 K homology domain-like, alpha/beta ALX04_RS15535 56e46f6441519e044e9ddf879e3b809a 140 SUPERFAMILY SSF82784 1 133 2.62E-21 T 28-03-2018 IPR003718 OsmC/Ohr family ALX04_RS15535 56e46f6441519e044e9ddf879e3b809a 140 Pfam PF02566 OsmC-like protein 38 133 1.1E-11 T 28-03-2018 IPR003718 OsmC/Ohr family ALX04_RS08845 1ced9b2d6def9b9cf7121ee1d5493871 459 SUPERFAMILY SSF103473 33 454 1.44E-40 T 28-03-2018 IPR020846 Major facilitator superfamily domain ALX04_RS08845 1ced9b2d6def9b9cf7121ee1d5493871 459 Gene3D G3DSA:1.20.1250.20 39 245 3.8E-14 T 28-03-2018 ALX04_RS08845 1ced9b2d6def9b9cf7121ee1d5493871 459 Gene3D G3DSA:1.20.1250.20 261 456 5.2E-19 T 28-03-2018 ALX04_RS08845 1ced9b2d6def9b9cf7121ee1d5493871 459 Pfam PF11700 Vacuole effluxer Atg22 like 181 451 4.7E-43 T 28-03-2018 IPR024671 Autophagy-related protein 22-like ALX04_RS08845 1ced9b2d6def9b9cf7121ee1d5493871 459 Pfam PF11700 Vacuole effluxer Atg22 like 48 176 4.4E-13 T 28-03-2018 IPR024671 Autophagy-related protein 22-like ALX04_RS10260 1a1dab5edab17fd286222f196588b9a7 127 SUPERFAMILY SSF103481 7 106 8.24E-16 T 28-03-2018 ALX04_RS10260 1a1dab5edab17fd286222f196588b9a7 127 Pfam PF00893 Small Multidrug Resistance protein 4 93 1.9E-18 T 28-03-2018 IPR000390 Small multidrug resistance protein family GO:0016021 ALX04_RS03440 e550aa3234a4b89256c5bcd1c596917a 411 SUPERFAMILY SSF53448 1 188 1.31E-37 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases ALX04_RS03440 e550aa3234a4b89256c5bcd1c596917a 411 Gene3D G3DSA:3.90.550.10 1 235 1.7E-39 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases ALX04_RS03440 e550aa3234a4b89256c5bcd1c596917a 411 Pfam PF00535 Glycosyl transferase family 2 1 99 5.1E-22 T 28-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 ALX04_RS00885 1b4713e8c33b669554a7aa54f85429e4 474 Pfam PF02934 GatB/GatE catalytic domain 6 285 4.0E-108 T 28-03-2018 IPR006075 Aspartyl/Glutamyl-tRNA(Gln) amidotransferase, subunit B/E, catalytic GO:0016874 ALX04_RS00885 1b4713e8c33b669554a7aa54f85429e4 474 SUPERFAMILY SSF89095 294 397 9.55E-32 T 28-03-2018 IPR003789 Aspartyl/glutamyl-tRNA amidotransferase subunit B-related GO:0016884 ALX04_RS00885 1b4713e8c33b669554a7aa54f85429e4 474 Hamap MF_00121 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B [gatB]. 2 472 36.417 T 28-03-2018 IPR004413 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit GO:0016884 ALX04_RS00885 1b4713e8c33b669554a7aa54f85429e4 474 TIGRFAM TIGR00133 gatB: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit 2 471 3.3E-167 T 28-03-2018 IPR004413 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit GO:0016884 ALX04_RS00885 1b4713e8c33b669554a7aa54f85429e4 474 SUPERFAMILY SSF55931 6 293 1.24E-118 T 28-03-2018 ALX04_RS00885 1b4713e8c33b669554a7aa54f85429e4 474 Pfam PF02637 GatB domain 325 471 2.9E-49 T 28-03-2018 IPR018027 Asn/Gln amidotransferase GO:0016884 ALX04_RS00885 1b4713e8c33b669554a7aa54f85429e4 474 ProSitePatterns PS01234 Glutamyl-tRNA(Gln) amidotransferase subunit B signature. 141 155 - T 28-03-2018 IPR017958 Glutamyl-tRNA(Gln) amidotransferase, subunit B, conserved site GO:0016884 ALX04_RS00885 1b4713e8c33b669554a7aa54f85429e4 474 Gene3D G3DSA:1.10.10.410 411 472 2.8E-21 T 28-03-2018 IPR023168 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, C-terminal ALX04_RS00885 1b4713e8c33b669554a7aa54f85429e4 474 SMART SM00845 325 471 4.2E-71 T 28-03-2018 IPR018027 Asn/Gln amidotransferase GO:0016884 ALX04_RS07470 e3f2ef173de3765f7cb369a69ef9f84d 583 Pfam PF02779 Transketolase, pyrimidine binding domain 282 442 2.5E-26 T 28-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain ALX04_RS07470 e3f2ef173de3765f7cb369a69ef9f84d 583 Pfam PF13292 1-deoxy-D-xylulose-5-phosphate synthase 201 245 2.2E-5 T 28-03-2018 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 ALX04_RS07470 e3f2ef173de3765f7cb369a69ef9f84d 583 Pfam PF13292 1-deoxy-D-xylulose-5-phosphate synthase 6 198 2.7E-75 T 28-03-2018 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 ALX04_RS07470 e3f2ef173de3765f7cb369a69ef9f84d 583 SMART SM00861 281 445 3.0E-42 T 28-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain ALX04_RS07470 e3f2ef173de3765f7cb369a69ef9f84d 583 SUPERFAMILY SSF52922 453 581 4.19E-21 T 28-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 ALX04_RS07470 e3f2ef173de3765f7cb369a69ef9f84d 583 Gene3D G3DSA:3.40.50.970 1 271 3.9E-67 T 28-03-2018 ALX04_RS07470 e3f2ef173de3765f7cb369a69ef9f84d 583 Gene3D G3DSA:3.40.50.970 272 449 9.9E-38 T 28-03-2018 ALX04_RS07470 e3f2ef173de3765f7cb369a69ef9f84d 583 Gene3D G3DSA:3.40.50.920 455 583 8.2E-26 T 28-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 ALX04_RS07470 e3f2ef173de3765f7cb369a69ef9f84d 583 SUPERFAMILY SSF52518 256 443 3.3E-46 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold ALX04_RS07470 e3f2ef173de3765f7cb369a69ef9f84d 583 SUPERFAMILY SSF52518 3 310 4.24E-62 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold ALX04_RS07470 e3f2ef173de3765f7cb369a69ef9f84d 583 Pfam PF02780 Transketolase, C-terminal domain 455 573 1.9E-17 T 28-03-2018 IPR033248 Transketolase, C-terminal domain ALX04_RS07470 e3f2ef173de3765f7cb369a69ef9f84d 583 ProSitePatterns PS00801 Transketolase signature 1. 31 50 - T 28-03-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 ALX04_RS09255 0eb5a4c8d1b616ffafae133521d40f1a 200 Pfam PF13630 SdpI/YhfL protein family 125 187 2.2E-7 T 28-03-2018 IPR025962 SdpI/YhfL protein family ALX04_RS11805 f646237e9e43971fa9f3e1bfc733184e 141 SMART SM00226 2 135 2.0E-42 T 28-03-2018 IPR023485 Phosphotyrosine protein phosphatase I superfamily ALX04_RS11805 f646237e9e43971fa9f3e1bfc733184e 141 Pfam PF01451 Low molecular weight phosphotyrosine protein phosphatase 4 132 1.7E-21 T 28-03-2018 IPR023485 Phosphotyrosine protein phosphatase I superfamily ALX04_RS11805 f646237e9e43971fa9f3e1bfc733184e 141 Gene3D G3DSA:3.40.50.2300 1 135 9.5E-36 T 28-03-2018 ALX04_RS11805 f646237e9e43971fa9f3e1bfc733184e 141 TIGRFAM TIGR02691 arsC_pI258_fam: arsenate reductase (thioredoxin) 4 132 8.1E-67 T 28-03-2018 IPR014064 Arsenate reductase ArsC GO:0004725|GO:0030612|GO:0046685 ALX04_RS11805 f646237e9e43971fa9f3e1bfc733184e 141 SUPERFAMILY SSF52788 1 134 2.09E-42 T 28-03-2018 IPR023485 Phosphotyrosine protein phosphatase I superfamily ALX04_RS08065 ab3402bc04f5f6eb6f0e90857f94946f 497 Gene3D G3DSA:3.40.50.1100 107 208 2.5E-17 T 28-03-2018 ALX04_RS08065 ab3402bc04f5f6eb6f0e90857f94946f 497 Pfam PF14821 Threonine synthase N terminus 5 81 7.3E-22 T 28-03-2018 IPR029144 Threonine synthase, N-terminal ALX04_RS08065 ab3402bc04f5f6eb6f0e90857f94946f 497 TIGRFAM TIGR00260 thrC: threonine synthase 92 442 3.5E-72 T 28-03-2018 IPR004450 Threonine synthase-like ALX04_RS08065 ab3402bc04f5f6eb6f0e90857f94946f 497 SUPERFAMILY SSF53686 3 482 4.0E-143 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme ALX04_RS08065 ab3402bc04f5f6eb6f0e90857f94946f 497 Gene3D G3DSA:3.90.1380.10 1 90 1.6E-24 T 28-03-2018 IPR029144 Threonine synthase, N-terminal ALX04_RS08065 ab3402bc04f5f6eb6f0e90857f94946f 497 Gene3D G3DSA:3.40.50.1100 209 445 6.3E-78 T 28-03-2018 ALX04_RS08065 ab3402bc04f5f6eb6f0e90857f94946f 497 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 103 425 8.0E-15 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme ALX04_RS10175 40e6e8a07b040694eddfb131759a55e3 444 Gene3D G3DSA:3.30.390.30 334 442 8.7E-14 T 28-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 ALX04_RS10175 40e6e8a07b040694eddfb131759a55e3 444 SUPERFAMILY SSF55424 335 437 2.92E-17 T 28-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 ALX04_RS10175 40e6e8a07b040694eddfb131759a55e3 444 SUPERFAMILY SSF51905 7 360 1.68E-47 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ALX04_RS10175 40e6e8a07b040694eddfb131759a55e3 444 Gene3D G3DSA:3.50.50.60 156 206 2.9E-10 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ALX04_RS10175 40e6e8a07b040694eddfb131759a55e3 444 Gene3D G3DSA:3.50.50.60 207 333 2.5E-20 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ALX04_RS10175 40e6e8a07b040694eddfb131759a55e3 444 PIRSF PIRSF000350 1 435 3.3E-64 T 28-03-2018 ALX04_RS10175 40e6e8a07b040694eddfb131759a55e3 444 Gene3D G3DSA:3.50.50.60 1 155 6.4E-19 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ALX04_RS10175 40e6e8a07b040694eddfb131759a55e3 444 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 169 187 8.1E-28 T 28-03-2018 ALX04_RS10175 40e6e8a07b040694eddfb131759a55e3 444 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 253 269 8.1E-28 T 28-03-2018 ALX04_RS10175 40e6e8a07b040694eddfb131759a55e3 444 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 132 150 8.1E-28 T 28-03-2018 ALX04_RS10175 40e6e8a07b040694eddfb131759a55e3 444 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 9 28 8.1E-28 T 28-03-2018 ALX04_RS10175 40e6e8a07b040694eddfb131759a55e3 444 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 281 303 8.1E-28 T 28-03-2018 ALX04_RS10175 40e6e8a07b040694eddfb131759a55e3 444 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 334 355 6.4E-43 T 28-03-2018 ALX04_RS10175 40e6e8a07b040694eddfb131759a55e3 444 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 135 144 6.4E-43 T 28-03-2018 ALX04_RS10175 40e6e8a07b040694eddfb131759a55e3 444 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 254 268 6.4E-43 T 28-03-2018 ALX04_RS10175 40e6e8a07b040694eddfb131759a55e3 444 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 296 303 6.4E-43 T 28-03-2018 ALX04_RS10175 40e6e8a07b040694eddfb131759a55e3 444 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 396 411 6.4E-43 T 28-03-2018 ALX04_RS10175 40e6e8a07b040694eddfb131759a55e3 444 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 8 30 6.4E-43 T 28-03-2018 ALX04_RS10175 40e6e8a07b040694eddfb131759a55e3 444 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 40 55 6.4E-43 T 28-03-2018 ALX04_RS10175 40e6e8a07b040694eddfb131759a55e3 444 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 169 194 6.4E-43 T 28-03-2018 ALX04_RS10175 40e6e8a07b040694eddfb131759a55e3 444 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 418 438 6.4E-43 T 28-03-2018 ALX04_RS10175 40e6e8a07b040694eddfb131759a55e3 444 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 7 315 8.1E-56 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ALX04_RS10175 40e6e8a07b040694eddfb131759a55e3 444 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 338 437 3.9E-8 T 28-03-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 ALX04_RS02110 acb5f8d1ed278193821682f228b81cc2 404 SUPERFAMILY SSF142695 210 376 2.75E-61 T 28-03-2018 IPR032677 GTP cyclohydrolase II KEGG: 00740+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539 ALX04_RS02110 acb5f8d1ed278193821682f228b81cc2 404 SUPERFAMILY SSF55821 4 200 5.95E-69 T 28-03-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain ALX04_RS02110 acb5f8d1ed278193821682f228b81cc2 404 Gene3D G3DSA:3.90.870.10 1 209 1.6E-75 T 28-03-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain ALX04_RS02110 acb5f8d1ed278193821682f228b81cc2 404 TIGRFAM TIGR00505 ribA: GTP cyclohydrolase II 212 396 6.6E-73 T 28-03-2018 IPR000926 GTP cyclohydrolase II, RibA GO:0003935|GO:0009231 KEGG: 00740+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539 ALX04_RS02110 acb5f8d1ed278193821682f228b81cc2 404 PIRSF PIRSF001259 2 403 1.1E-142 T 28-03-2018 ALX04_RS02110 acb5f8d1ed278193821682f228b81cc2 404 Hamap MF_00179 GTP cyclohydrolase-2 [ribA]. 204 399 39.919 T 28-03-2018 IPR000926 GTP cyclohydrolase II, RibA GO:0003935|GO:0009231 KEGG: 00740+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539 ALX04_RS02110 acb5f8d1ed278193821682f228b81cc2 404 Pfam PF00926 3,4-dihydroxy-2-butanone 4-phosphate synthase 9 197 1.3E-71 T 28-03-2018 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 ALX04_RS02110 acb5f8d1ed278193821682f228b81cc2 404 Pfam PF00925 GTP cyclohydrolase II 211 373 7.2E-65 T 28-03-2018 IPR032677 GTP cyclohydrolase II KEGG: 00740+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539 ALX04_RS02110 acb5f8d1ed278193821682f228b81cc2 404 TIGRFAM TIGR00506 ribB: 3,4-dihydroxy-2-butanone-4-phosphate synthase 4 197 3.6E-62 T 28-03-2018 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 ALX04_RS10550 64913ecc3b461b9a04f30f65940f38cc 212 Pfam PF13460 NAD(P)H-binding 8 189 2.3E-54 T 28-03-2018 IPR016040 NAD(P)-binding domain ALX04_RS10550 64913ecc3b461b9a04f30f65940f38cc 212 SUPERFAMILY SSF51735 1 190 1.45E-31 T 28-03-2018 IPR016040 NAD(P)-binding domain ALX04_RS10550 64913ecc3b461b9a04f30f65940f38cc 212 Gene3D G3DSA:3.40.50.720 2 204 2.1E-22 T 28-03-2018 ALX04_RS04150 6518b3140df69dec68967503e6d75f6a 177 Gene3D G3DSA:1.10.357.10 2 129 1.3E-7 T 28-03-2018 ALX04_RS04150 6518b3140df69dec68967503e6d75f6a 177 SUPERFAMILY SSF46689 5 72 1.84E-7 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 ALX04_RS07810 3108eea31f82b5f47ef5e1a6e9baa9d9 237 ProSitePatterns PS00156 Orotidine 5'-phosphate decarboxylase active site. 57 70 - T 28-03-2018 IPR018089 Orotidine 5'-phosphate decarboxylase, active site GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 ALX04_RS07810 3108eea31f82b5f47ef5e1a6e9baa9d9 237 Hamap MF_01200_B Orotidine 5'-phosphate decarboxylase [pyrF]. 2 236 39.236 T 28-03-2018 IPR014732 Orotidine 5'-phosphate decarboxylase GO:0004590|GO:0044205 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 ALX04_RS07810 3108eea31f82b5f47ef5e1a6e9baa9d9 237 Gene3D G3DSA:3.20.20.70 1 236 1.0E-56 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 ALX04_RS07810 3108eea31f82b5f47ef5e1a6e9baa9d9 237 SMART SM00934 4 231 2.2E-84 T 28-03-2018 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 ALX04_RS07810 3108eea31f82b5f47ef5e1a6e9baa9d9 237 SUPERFAMILY SSF51366 1 235 1.29E-63 T 28-03-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 ALX04_RS07810 3108eea31f82b5f47ef5e1a6e9baa9d9 237 TIGRFAM TIGR01740 pyrF: orotidine 5'-phosphate decarboxylase 6 231 1.1E-55 T 28-03-2018 IPR014732 Orotidine 5'-phosphate decarboxylase GO:0004590|GO:0044205 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 ALX04_RS07810 3108eea31f82b5f47ef5e1a6e9baa9d9 237 Pfam PF00215 Orotidine 5'-phosphate decarboxylase / HUMPS family 4 230 1.4E-44 T 28-03-2018 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 ALX04_RS14425 3834464cd7635a53e69753ec46b074de 265 SUPERFAMILY SSF56784 3 258 2.14E-49 T 28-03-2018 IPR023214 HAD-like domain ALX04_RS14425 3834464cd7635a53e69753ec46b074de 265 Gene3D G3DSA:3.40.50.1000 92 262 3.4E-21 T 28-03-2018 IPR023214 HAD-like domain ALX04_RS14425 3834464cd7635a53e69753ec46b074de 265 Hamap MF_01375 Phosphonoacetaldehyde hydrolase [phnX]. 1 265 90.748 T 28-03-2018 IPR006323 Phosphonoacetaldehyde hydrolase GO:0019700|GO:0050194 KEGG: 00440+3.11.1.1 ALX04_RS14425 3834464cd7635a53e69753ec46b074de 265 Pfam PF13419 Haloacid dehalogenase-like hydrolase 6 199 6.8E-11 T 28-03-2018 IPR023214 HAD-like domain ALX04_RS14425 3834464cd7635a53e69753ec46b074de 265 TIGRFAM TIGR01422 phosphonatase: phosphonoacetaldehyde hydrolase 2 255 1.4E-106 T 28-03-2018 IPR006323 Phosphonoacetaldehyde hydrolase GO:0019700|GO:0050194 KEGG: 00440+3.11.1.1 ALX04_RS14425 3834464cd7635a53e69753ec46b074de 265 Gene3D G3DSA:1.10.150.240 21 91 1.1E-24 T 28-03-2018 IPR023198 Phosphoglycolate phosphatase, domain 2 ALX04_RS12245 03e556388e5d4dbb48cf60be2d3e59ac 305 ProSitePatterns PS00211 ABC transporters family signature. 133 147 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 ALX04_RS12245 03e556388e5d4dbb48cf60be2d3e59ac 305 Gene3D G3DSA:3.40.50.300 3 246 5.9E-58 T 28-03-2018 ALX04_RS12245 03e556388e5d4dbb48cf60be2d3e59ac 305 SUPERFAMILY SSF52540 4 220 2.77E-55 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase ALX04_RS12245 03e556388e5d4dbb48cf60be2d3e59ac 305 SMART SM00382 31 215 8.1E-11 T 28-03-2018 IPR003593 AAA+ ATPase domain ALX04_RS12245 03e556388e5d4dbb48cf60be2d3e59ac 305 Pfam PF00005 ABC transporter 22 161 1.7E-25 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 ALX04_RS13125 6e91688d37c76f555947db1f83546bf4 501 Gene3D G3DSA:2.60.40.420 327 494 9.1E-34 T 28-03-2018 IPR008972 Cupredoxin ALX04_RS13125 6e91688d37c76f555947db1f83546bf4 501 SUPERFAMILY SSF49503 179 296 7.11E-26 T 28-03-2018 IPR008972 Cupredoxin ALX04_RS13125 6e91688d37c76f555947db1f83546bf4 501 Gene3D G3DSA:2.60.40.420 173 307 4.2E-26 T 28-03-2018 IPR008972 Cupredoxin ALX04_RS13125 6e91688d37c76f555947db1f83546bf4 501 SUPERFAMILY SSF49503 35 175 1.12E-30 T 28-03-2018 IPR008972 Cupredoxin ALX04_RS13125 6e91688d37c76f555947db1f83546bf4 501 Pfam PF07732 Multicopper oxidase 58 173 7.2E-22 T 28-03-2018 IPR011707 Multicopper oxidase, type 3 GO:0005507 ALX04_RS13125 6e91688d37c76f555947db1f83546bf4 501 Gene3D G3DSA:2.60.40.420 28 171 1.6E-28 T 28-03-2018 IPR008972 Cupredoxin ALX04_RS13125 6e91688d37c76f555947db1f83546bf4 501 SUPERFAMILY SSF49503 332 462 1.21E-32 T 28-03-2018 IPR008972 Cupredoxin ALX04_RS13125 6e91688d37c76f555947db1f83546bf4 501 ProSitePatterns PS00080 Multicopper oxidases signature 2. 447 458 - T 28-03-2018 IPR002355 Multicopper oxidase, copper-binding site GO:0005507 ALX04_RS13125 6e91688d37c76f555947db1f83546bf4 501 Pfam PF07731 Multicopper oxidase 346 464 7.4E-28 T 28-03-2018 IPR011706 Multicopper oxidase, type 2 GO:0005507|GO:0016491|GO:0055114 ALX04_RS13125 6e91688d37c76f555947db1f83546bf4 501 ProSitePatterns PS00079 Multicopper oxidases signature 1. 442 462 - T 28-03-2018 IPR033138 Multicopper oxidases, conserved site ALX04_RS03885 5f2375d3dda5293f98f75f95e561c641 407 Hamap MF_01263 CCA-adding enzyme [cca]. 7 402 40.889 T 28-03-2018 IPR023068 CCA-adding enzyme, firmicutes GO:0001680|GO:0004810|GO:0016437 ALX04_RS03885 5f2375d3dda5293f98f75f95e561c641 407 SUPERFAMILY SSF81891 145 399 8.11E-54 T 28-03-2018 ALX04_RS03885 5f2375d3dda5293f98f75f95e561c641 407 Gene3D G3DSA:3.30.460.10 8 146 7.8E-47 T 28-03-2018 ALX04_RS03885 5f2375d3dda5293f98f75f95e561c641 407 Pfam PF12627 Probable RNA and SrmB- binding site of polymerase A 174 232 1.8E-16 T 28-03-2018 IPR032828 tRNA nucleotidyltransferase/poly(A) polymerase, RNA and SrmB- binding domain Reactome: R-HSA-6784531|Reactome: R-HSA-6785470 ALX04_RS03885 5f2375d3dda5293f98f75f95e561c641 407 SUPERFAMILY SSF81301 10 143 3.6E-42 T 28-03-2018 ALX04_RS03885 5f2375d3dda5293f98f75f95e561c641 407 Gene3D G3DSA:1.10.3090.10 147 401 6.5E-39 T 28-03-2018 ALX04_RS03885 5f2375d3dda5293f98f75f95e561c641 407 Pfam PF01743 Poly A polymerase head domain 27 147 4.4E-38 T 28-03-2018 IPR002646 Poly A polymerase, head domain GO:0003723|GO:0006396|GO:0016779 Reactome: R-HSA-6784531|Reactome: R-HSA-6785470 ALX04_RS03885 5f2375d3dda5293f98f75f95e561c641 407 Pfam PF13735 tRNA nucleotidyltransferase domain 2 putative 250 398 8.2E-44 T 28-03-2018 IPR032810 CCA-adding enzyme, C-terminal ALX04_RS16030 27bdbd6ce227f1f8aa58322981f66ebd 184 Gene3D G3DSA:1.10.10.60 139 183 2.4E-9 T 28-03-2018 ALX04_RS16030 27bdbd6ce227f1f8aa58322981f66ebd 184 Gene3D G3DSA:1.20.5.40 107 133 4.9E-14 T 28-03-2018 ALX04_RS16030 27bdbd6ce227f1f8aa58322981f66ebd 184 ProSitePatterns PS00397 Site-specific recombinases active site. 5 13 - T 28-03-2018 IPR006118 Recombinase, conserved site GO:0000150|GO:0006310 ALX04_RS16030 27bdbd6ce227f1f8aa58322981f66ebd 184 SUPERFAMILY SSF46689 140 182 2.09E-7 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 ALX04_RS16030 27bdbd6ce227f1f8aa58322981f66ebd 184 Pfam PF00239 Resolvase, N terminal domain 3 132 7.8E-39 T 28-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 ALX04_RS16030 27bdbd6ce227f1f8aa58322981f66ebd 184 Gene3D G3DSA:3.40.50.1390 2 106 1.6E-31 T 28-03-2018 ALX04_RS16030 27bdbd6ce227f1f8aa58322981f66ebd 184 SMART SM00857 2 142 3.9E-49 T 28-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 ALX04_RS16030 27bdbd6ce227f1f8aa58322981f66ebd 184 SUPERFAMILY SSF53041 1 132 1.96E-40 T 28-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 ALX04_RS12045 01479c0380e70bc47774d62d071c81fa 217 SUPERFAMILY SSF51391 8 214 1.96E-57 T 28-03-2018 IPR022998 Thiamine phosphate synthase/TenI KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 ALX04_RS12045 01479c0380e70bc47774d62d071c81fa 217 Hamap MF_00097 Thiamine-phosphate synthase [thiE]. 10 215 25.558 T 28-03-2018 IPR034291 Thiamine phosphate synthase GO:0004789|GO:0009228 KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 ALX04_RS12045 01479c0380e70bc47774d62d071c81fa 217 Gene3D G3DSA:3.20.20.70 1 215 5.1E-39 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 ALX04_RS12045 01479c0380e70bc47774d62d071c81fa 217 Pfam PF02581 Thiamine monophosphate synthase 13 196 3.0E-56 T 28-03-2018 IPR022998 Thiamine phosphate synthase/TenI KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 ALX04_RS12045 01479c0380e70bc47774d62d071c81fa 217 TIGRFAM TIGR00693 thiE: thiamine-phosphate diphosphorylase 12 209 3.0E-56 T 28-03-2018 IPR034291 Thiamine phosphate synthase GO:0004789|GO:0009228 KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 ALX04_RS04075 4e72abd77a7a615ccb2773f67f2552f8 324 Gene3D G3DSA:3.90.180.10 149 318 7.3E-7 T 28-03-2018 ALX04_RS04075 4e72abd77a7a615ccb2773f67f2552f8 324 SUPERFAMILY SSF51735 117 282 9.25E-19 T 28-03-2018 IPR016040 NAD(P)-binding domain ALX04_RS04075 4e72abd77a7a615ccb2773f67f2552f8 324 SMART SM00829 10 317 3.8E-7 T 28-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 ALX04_RS04075 4e72abd77a7a615ccb2773f67f2552f8 324 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 28 85 5.6E-7 T 28-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 ALX04_RS04075 4e72abd77a7a615ccb2773f67f2552f8 324 Gene3D G3DSA:3.90.180.10 1 148 1.4E-34 T 28-03-2018 ALX04_RS04075 4e72abd77a7a615ccb2773f67f2552f8 324 SUPERFAMILY SSF50129 5 148 7.61E-29 T 28-03-2018 IPR011032 GroES-like ALX04_RS04075 4e72abd77a7a615ccb2773f67f2552f8 324 Pfam PF13602 Zinc-binding dehydrogenase 189 317 6.5E-12 T 28-03-2018 ALX04_RS04495 b14f913d0e214b902f1a4ced20a74132 404 PIRSF PIRSF016636 7 396 4.9E-87 T 28-03-2018 IPR024194 Alginate O-acetyltransferase AlgI/D-alanyl transfer protein DltB ALX04_RS04495 b14f913d0e214b902f1a4ced20a74132 404 PIRSF PIRSF500216 3 400 1.0E-176 T 28-03-2018 IPR024024 D-alanyl transfer protein DltB ALX04_RS04495 b14f913d0e214b902f1a4ced20a74132 404 TIGRFAM TIGR04091 LTA_dltB: D-alanyl-lipoteichoic acid biosynthesis protein DltB 6 395 9.8E-172 T 28-03-2018 IPR024024 D-alanyl transfer protein DltB ALX04_RS04495 b14f913d0e214b902f1a4ced20a74132 404 Pfam PF03062 MBOAT, membrane-bound O-acyltransferase family 138 389 2.4E-13 T 28-03-2018 IPR004299 Membrane bound O-acyl transferase, MBOAT ALX04_RS13600 3e96c2890507504d03b7828c1dc6100e 269 TIGRFAM TIGR00099 Cof-subfamily: Cof-like hydrolase 5 263 1.5E-64 T 28-03-2018 IPR000150 Cof family GO:0016787 ALX04_RS13600 3e96c2890507504d03b7828c1dc6100e 269 ProSitePatterns PS01228 Hypothetical cof family signature 1. 5 16 - T 28-03-2018 ALX04_RS13600 3e96c2890507504d03b7828c1dc6100e 269 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 5 236 4.0E-27 T 28-03-2018 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 ALX04_RS13600 3e96c2890507504d03b7828c1dc6100e 269 Pfam PF08282 haloacid dehalogenase-like hydrolase 6 263 2.4E-68 T 28-03-2018 IPR023214 HAD-like domain ALX04_RS13600 3e96c2890507504d03b7828c1dc6100e 269 SUPERFAMILY SSF56784 1 266 1.94E-76 T 28-03-2018 IPR023214 HAD-like domain ALX04_RS13600 3e96c2890507504d03b7828c1dc6100e 269 ProSitePatterns PS01229 Hypothetical cof family signature 2. 217 239 - T 28-03-2018 ALX04_RS13600 3e96c2890507504d03b7828c1dc6100e 269 Gene3D G3DSA:3.40.50.1000 1 269 1.9E-46 T 28-03-2018 IPR023214 HAD-like domain ALX04_RS03645 827c6e5a740d635222f0c284d915816a 446 PIRSF PIRSF006060 1 443 2.8E-62 T 28-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 ALX04_RS03645 827c6e5a740d635222f0c284d915816a 446 Pfam PF00324 Amino acid permease 14 438 1.2E-108 T 28-03-2018 IPR004841 Amino acid permease/ SLC12A domain GO:0006810|GO:0016020|GO:0055085 ALX04_RS12190 e5d0b58de6c9de0bfbdd86ed0902f6ba 369 SUPERFAMILY SSF51395 4 337 1.98E-90 T 28-03-2018 ALX04_RS12190 e5d0b58de6c9de0bfbdd86ed0902f6ba 369 Gene3D G3DSA:3.20.20.70 1 349 8.4E-96 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 ALX04_RS12190 e5d0b58de6c9de0bfbdd86ed0902f6ba 369 Pfam PF00724 NADH:flavin oxidoreductase / NADH oxidase family 6 333 1.8E-66 T 28-03-2018 IPR001155 NADH:flavin oxidoreductase/NADH oxidase, N-terminal GO:0010181|GO:0016491|GO:0055114 ALX04_RS09305 577189ce64f4db1c569a9ae885a88bbd 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 81 92 6.6E-24 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR ALX04_RS09305 577189ce64f4db1c569a9ae885a88bbd 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 6.6E-24 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR ALX04_RS09305 577189ce64f4db1c569a9ae885a88bbd 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 154 173 6.6E-24 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR ALX04_RS09305 577189ce64f4db1c569a9ae885a88bbd 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 177 194 6.6E-24 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR ALX04_RS09305 577189ce64f4db1c569a9ae885a88bbd 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 128 144 6.6E-24 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR ALX04_RS09305 577189ce64f4db1c569a9ae885a88bbd 247 SUPERFAMILY SSF51735 1 233 3.66E-65 T 28-03-2018 IPR016040 NAD(P)-binding domain ALX04_RS09305 577189ce64f4db1c569a9ae885a88bbd 247 Gene3D G3DSA:3.40.50.720 1 242 5.5E-58 T 28-03-2018 ALX04_RS09305 577189ce64f4db1c569a9ae885a88bbd 247 Pfam PF00106 short chain dehydrogenase 6 200 3.6E-56 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR ALX04_RS09305 577189ce64f4db1c569a9ae885a88bbd 247 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 141 169 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 ALX04_RS09305 577189ce64f4db1c569a9ae885a88bbd 247 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 134 142 1.5E-7 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR ALX04_RS09305 577189ce64f4db1c569a9ae885a88bbd 247 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 81 92 1.5E-7 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR ALX04_RS09305 577189ce64f4db1c569a9ae885a88bbd 247 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 154 173 1.5E-7 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR ALX04_RS07325 4d968a0012ee9ee175b61a081d73dfe6 387 Pfam PF06271 RDD family 230 382 2.5E-10 T 28-03-2018 IPR010432 RDD ALX04_RS07325 4d968a0012ee9ee175b61a081d73dfe6 387 PIRSF PIRSF031578 18 387 9.4E-140 T 28-03-2018 IPR021192 Uncharacterised conserved protein UCP031578, VanZ/RDD-type ALX04_RS07325 4d968a0012ee9ee175b61a081d73dfe6 387 Pfam PF04892 VanZ like family 65 207 3.5E-20 T 28-03-2018 IPR006976 VanZ-like ALX04_RS13080 121de5c81b7e6d23de4c665f15ae218b 363 SUPERFAMILY SSF52540 38 237 4.82E-45 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase ALX04_RS13080 121de5c81b7e6d23de4c665f15ae218b 363 Pfam PF00005 ABC transporter 43 174 4.1E-17 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 ALX04_RS13080 121de5c81b7e6d23de4c665f15ae218b 363 Gene3D G3DSA:3.40.50.300 4 312 1.9E-49 T 28-03-2018 ALX04_RS13080 121de5c81b7e6d23de4c665f15ae218b 363 SMART SM00382 52 232 1.9E-10 T 28-03-2018 IPR003593 AAA+ ATPase domain ALX04_RS10620 ab08105f7a307420109ebfdbcdeba753 457 Pfam PF02133 Permease for cytosine/purines, uracil, thiamine, allantoin 13 422 1.1E-52 T 28-03-2018 IPR001248 Purine-cytosine permease GO:0005215|GO:0016020|GO:0055085 ALX04_RS10620 ab08105f7a307420109ebfdbcdeba753 457 PIRSF PIRSF002744 3 456 1.7E-53 T 28-03-2018 IPR026030 Purine-cytosine permease Fcy2/21/22 GO:0005215|GO:0016021|GO:0055085 ALX04_RS05060 82a7ff1bed54df2be5a8de98521ae09f 172 Gene3D G3DSA:3.40.50.2020 2 171 1.4E-39 T 28-03-2018 ALX04_RS05060 82a7ff1bed54df2be5a8de98521ae09f 172 TIGRFAM TIGR01090 apt: adenine phosphoribosyltransferase 5 171 2.8E-68 T 28-03-2018 IPR005764 Adenine phosphoribosyl transferase GO:0003999|GO:0005737|GO:0006168 KEGG: 00230+2.4.2.7|MetaCyc: PWY-6605|MetaCyc: PWY-6610|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-6798695|Reactome: R-HSA-74217 ALX04_RS05060 82a7ff1bed54df2be5a8de98521ae09f 172 SUPERFAMILY SSF53271 2 164 5.11E-49 T 28-03-2018 IPR029057 Phosphoribosyltransferase-like ALX04_RS05060 82a7ff1bed54df2be5a8de98521ae09f 172 Pfam PF00156 Phosphoribosyl transferase domain 41 169 6.4E-16 T 28-03-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 ALX04_RS05060 82a7ff1bed54df2be5a8de98521ae09f 172 Hamap MF_00004 Adenine phosphoribosyltransferase [apt]. 5 172 38.03 T 28-03-2018 IPR005764 Adenine phosphoribosyl transferase GO:0003999|GO:0005737|GO:0006168 KEGG: 00230+2.4.2.7|MetaCyc: PWY-6605|MetaCyc: PWY-6610|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-6798695|Reactome: R-HSA-74217 ALX04_RS05235 1376a9600345f2269926066504523678 89 Gene3D G3DSA:1.10.287.10 2 89 7.4E-33 T 28-03-2018 ALX04_RS05235 1376a9600345f2269926066504523678 89 Pfam PF00312 Ribosomal protein S15 8 88 2.6E-35 T 28-03-2018 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 ALX04_RS05235 1376a9600345f2269926066504523678 89 TIGRFAM TIGR00952 S15_bact: ribosomal protein uS15 5 89 2.4E-37 T 28-03-2018 IPR005290 Ribosomal protein S15, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 ALX04_RS05235 1376a9600345f2269926066504523678 89 ProSitePatterns PS00362 Ribosomal protein S15 signature. 39 69 - T 28-03-2018 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 ALX04_RS05235 1376a9600345f2269926066504523678 89 ProDom PD157043 RIBOSOMAL S15 RIBONUCLEOPROTEIN RRNA-BINDING RNA-BINDING 30S CHLOROPLAST S15 MITOCHONDRIAL TYPE 10 88 1.0E-39 T 28-03-2018 ALX04_RS05235 1376a9600345f2269926066504523678 89 SUPERFAMILY SSF47060 3 89 2.56E-34 T 28-03-2018 IPR009068 S15/NS1, RNA-binding ALX04_RS05235 1376a9600345f2269926066504523678 89 SMART SM01387 8 88 3.6E-48 T 28-03-2018 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 ALX04_RS05235 1376a9600345f2269926066504523678 89 Hamap MF_01343_B 30S ribosomal protein S15 [rpsO]. 3 89 22.405 T 28-03-2018 IPR005290 Ribosomal protein S15, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 ALX04_RS16025 e0c28254a6d4d1a9bedac35c6214c81b 145 SMART SM00347 30 130 2.8E-16 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 ALX04_RS16025 e0c28254a6d4d1a9bedac35c6214c81b 145 Pfam PF01047 MarR family 38 95 1.9E-13 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 ALX04_RS16025 e0c28254a6d4d1a9bedac35c6214c81b 145 Gene3D G3DSA:1.10.10.10 2 145 1.0E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS16025 e0c28254a6d4d1a9bedac35c6214c81b 145 SUPERFAMILY SSF46785 14 139 4.5E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS14035 3a8ff2bfb3f52a01c6461b6e5d5b84e2 280 SUPERFAMILY SSF56300 4 218 3.47E-29 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like ALX04_RS14035 3a8ff2bfb3f52a01c6461b6e5d5b84e2 280 Gene3D G3DSA:3.60.21.10 3 269 2.7E-25 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like ALX04_RS14035 3a8ff2bfb3f52a01c6461b6e5d5b84e2 280 Pfam PF00149 Calcineurin-like phosphoesterase 5 209 1.8E-8 T 28-03-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 ALX04_RS11785 75087b7e6c30a34fb466a831963fdd55 789 Gene3D G3DSA:3.40.50.360 1 185 3.1E-26 T 28-03-2018 IPR029039 Flavoprotein-like domain ALX04_RS11785 75087b7e6c30a34fb466a831963fdd55 789 Gene3D G3DSA:3.50.50.60 190 418 2.9E-16 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ALX04_RS11785 75087b7e6c30a34fb466a831963fdd55 789 Pfam PF00890 FAD binding domain 194 650 1.5E-35 T 28-03-2018 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 ALX04_RS11785 75087b7e6c30a34fb466a831963fdd55 789 Gene3D G3DSA:3.90.700.10 452 610 3.7E-24 T 28-03-2018 ALX04_RS11785 75087b7e6c30a34fb466a831963fdd55 789 Pfam PF04205 FMN-binding domain 709 781 4.6E-13 T 28-03-2018 IPR007329 FMN-binding GO:0010181|GO:0016020 ALX04_RS11785 75087b7e6c30a34fb466a831963fdd55 789 SUPERFAMILY SSF52218 1 172 2.9E-37 T 28-03-2018 IPR029039 Flavoprotein-like domain ALX04_RS11785 75087b7e6c30a34fb466a831963fdd55 789 Pfam PF03358 NADPH-dependent FMN reductase 1 147 5.0E-30 T 28-03-2018 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 ALX04_RS11785 75087b7e6c30a34fb466a831963fdd55 789 SUPERFAMILY SSF51905 338 447 7.62E-31 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ALX04_RS11785 75087b7e6c30a34fb466a831963fdd55 789 SUPERFAMILY SSF51905 187 260 7.62E-31 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ALX04_RS11785 75087b7e6c30a34fb466a831963fdd55 789 SUPERFAMILY SSF51905 611 667 7.62E-31 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ALX04_RS11785 75087b7e6c30a34fb466a831963fdd55 789 SUPERFAMILY SSF51905 291 309 7.62E-31 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ALX04_RS11785 75087b7e6c30a34fb466a831963fdd55 789 SUPERFAMILY SSF56425 467 611 1.12E-23 T 28-03-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 ALX04_RS11785 75087b7e6c30a34fb466a831963fdd55 789 SMART SM00900 709 783 2.3E-18 T 28-03-2018 IPR007329 FMN-binding GO:0010181|GO:0016020 ALX04_RS13330 472d5b6cb0288e00601d5b9c78ff0242 458 TIGRFAM TIGR00796 livcs: branched-chain amino acid transport system II carrier protein 16 430 4.8E-107 T 28-03-2018 IPR004685 Branched-chain amino acid transport system II carrier protein GO:0015658|GO:0015803|GO:0016021 ALX04_RS13330 472d5b6cb0288e00601d5b9c78ff0242 458 Pfam PF05525 Branched-chain amino acid transport protein 10 440 8.9E-129 T 28-03-2018 IPR004685 Branched-chain amino acid transport system II carrier protein GO:0015658|GO:0015803|GO:0016021 ALX04_RS02505 a842ae1ff879bbcfaa851e562bde913d 255 SUPERFAMILY SSF75217 93 255 2.62E-39 T 28-03-2018 IPR029028 Alpha/beta knot methyltransferases ALX04_RS02505 a842ae1ff879bbcfaa851e562bde913d 255 Pfam PF00588 SpoU rRNA Methylase family 113 251 1.2E-33 T 28-03-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 ALX04_RS02505 a842ae1ff879bbcfaa851e562bde913d 255 SUPERFAMILY SSF55315 4 97 8.95E-23 T 28-03-2018 IPR029064 50S ribosomal protein L30e-like ALX04_RS02505 a842ae1ff879bbcfaa851e562bde913d 255 Pfam PF08032 RNA 2'-O ribose methyltransferase substrate binding 34 95 2.0E-5 T 28-03-2018 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 Reactome: R-HSA-6793080 ALX04_RS02505 a842ae1ff879bbcfaa851e562bde913d 255 SMART SM00967 31 100 4.3E-11 T 28-03-2018 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 Reactome: R-HSA-6793080 ALX04_RS02505 a842ae1ff879bbcfaa851e562bde913d 255 Gene3D G3DSA:3.40.1280.10 97 255 3.2E-41 T 28-03-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal ALX04_RS02505 a842ae1ff879bbcfaa851e562bde913d 255 Gene3D G3DSA:3.30.1330.30 3 96 7.2E-23 T 28-03-2018 IPR029064 50S ribosomal protein L30e-like ALX04_RS09275 eaad84ea0171fd187d8914f0cf2bde4b 214 Gene3D G3DSA:1.10.340.30 4 186 5.0E-51 T 28-03-2018 ALX04_RS09275 eaad84ea0171fd187d8914f0cf2bde4b 214 Pfam PF03352 Methyladenine glycosylase 20 182 1.4E-48 T 28-03-2018 IPR005019 Methyladenine glycosylase GO:0006284|GO:0008725 ALX04_RS09275 eaad84ea0171fd187d8914f0cf2bde4b 214 SUPERFAMILY SSF48150 15 182 5.81E-52 T 28-03-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 ALX04_RS04740 1ef7bb566495ba7845ffbaf2ec90e174 263 Gene3D G3DSA:3.40.50.300 3 261 1.4E-53 T 28-03-2018 ALX04_RS04740 1ef7bb566495ba7845ffbaf2ec90e174 263 SMART SM00382 37 220 4.6E-17 T 28-03-2018 IPR003593 AAA+ ATPase domain ALX04_RS04740 1ef7bb566495ba7845ffbaf2ec90e174 263 Pfam PF00005 ABC transporter 28 168 7.1E-31 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 ALX04_RS04740 1ef7bb566495ba7845ffbaf2ec90e174 263 ProSitePatterns PS00211 ABC transporters family signature. 141 155 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 ALX04_RS04740 1ef7bb566495ba7845ffbaf2ec90e174 263 SUPERFAMILY SSF52540 9 241 4.17E-60 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase ALX04_RS12335 7071f405e13621c1e941267e82f9d323 440 Pfam PF00128 Alpha amylase, catalytic domain 135 313 3.9E-17 T 28-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 ALX04_RS12335 7071f405e13621c1e941267e82f9d323 440 Pfam PF00128 Alpha amylase, catalytic domain 26 117 3.8E-23 T 28-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 ALX04_RS12335 7071f405e13621c1e941267e82f9d323 440 SMART SM00642 16 331 1.7E-26 T 28-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 ALX04_RS12335 7071f405e13621c1e941267e82f9d323 440 SUPERFAMILY SSF51445 9 346 4.04E-83 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily ALX04_RS12335 7071f405e13621c1e941267e82f9d323 440 Gene3D G3DSA:3.20.20.80 1 348 9.9E-82 T 28-03-2018 ALX04_RS05415 8ff414e9694f673b752fad9e904c4d88 243 Pfam PF13731 WxL domain surface cell wall-binding 65 232 1.3E-16 T 28-03-2018 IPR027994 WxL domain ALX04_RS05385 8bd6ebff419f1502efb898c43968684d 321 Gene3D G3DSA:3.40.50.2020 163 296 1.4E-33 T 28-03-2018 ALX04_RS05385 8bd6ebff419f1502efb898c43968684d 321 ProSitePatterns PS00114 Phosphoribosyl pyrophosphate synthase signature. 134 149 - T 28-03-2018 IPR000842 Phosphoribosyl pyrophosphate synthetase, conserved site GO:0000287|GO:0004749|GO:0009156|GO:0044249 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1|Reactome: R-HSA-73843 ALX04_RS05385 8bd6ebff419f1502efb898c43968684d 321 TIGRFAM TIGR01251 ribP_PPkin: ribose-phosphate diphosphokinase 11 318 3.9E-109 T 28-03-2018 IPR005946 Ribose-phosphate diphosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 ALX04_RS05385 8bd6ebff419f1502efb898c43968684d 321 Gene3D G3DSA:3.40.50.2020 7 162 5.8E-65 T 28-03-2018 ALX04_RS05385 8bd6ebff419f1502efb898c43968684d 321 Hamap MF_00583_B Ribose-phosphate pyrophosphokinase [prs]. 10 318 45.82 T 28-03-2018 IPR005946 Ribose-phosphate diphosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 ALX04_RS05385 8bd6ebff419f1502efb898c43968684d 321 SMART SM01400 10 126 9.0E-73 T 28-03-2018 ALX04_RS05385 8bd6ebff419f1502efb898c43968684d 321 SUPERFAMILY SSF53271 17 101 6.31E-5 T 28-03-2018 IPR029057 Phosphoribosyltransferase-like ALX04_RS05385 8bd6ebff419f1502efb898c43968684d 321 Pfam PF14572 Phosphoribosyl synthetase-associated domain 209 317 2.3E-22 T 28-03-2018 IPR005946 Ribose-phosphate diphosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 ALX04_RS05385 8bd6ebff419f1502efb898c43968684d 321 Pfam PF13793 N-terminal domain of ribose phosphate pyrophosphokinase 10 124 2.5E-48 T 28-03-2018 IPR029099 Ribose-phosphate pyrophosphokinase, N-terminal domain KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 ALX04_RS05385 8bd6ebff419f1502efb898c43968684d 321 SUPERFAMILY SSF53271 75 309 7.97E-54 T 28-03-2018 IPR029057 Phosphoribosyltransferase-like ALX04_RS13485 bef2f895881862fa5276bddbb529e8e0 337 SUPERFAMILY SSF51395 21 329 3.5E-48 T 28-03-2018 ALX04_RS13485 bef2f895881862fa5276bddbb529e8e0 337 Gene3D G3DSA:1.10.1200.80 261 336 0.0012 T 28-03-2018 IPR024036 tRNA-dihydrouridine synthase, putative, C-terminal GO:0016491|GO:0055114 ALX04_RS13485 bef2f895881862fa5276bddbb529e8e0 337 PIRSF PIRSF006621 10 337 1.6E-62 T 28-03-2018 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 ALX04_RS13485 bef2f895881862fa5276bddbb529e8e0 337 ProSitePatterns PS01136 Uncharacterized protein family UPF0034 signature. 108 126 - T 28-03-2018 IPR018517 tRNA-dihydrouridine synthase, conserved site GO:0008033|GO:0017150|GO:0050660|GO:0055114 ALX04_RS13485 bef2f895881862fa5276bddbb529e8e0 337 Gene3D G3DSA:3.20.20.70 19 258 3.1E-29 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 ALX04_RS13485 bef2f895881862fa5276bddbb529e8e0 337 Pfam PF01207 Dihydrouridine synthase (Dus) 24 254 1.2E-39 T 28-03-2018 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 ALX04_RS15570 64e585e115c22a22de21af4a42fecb14 433 Gene3D G3DSA:3.30.1490.100 264 378 3.2E-21 T 28-03-2018 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 ALX04_RS15570 64e585e115c22a22de21af4a42fecb14 433 Gene3D G3DSA:1.10.150.20 181 263 4.2E-14 T 28-03-2018 ALX04_RS15570 64e585e115c22a22de21af4a42fecb14 433 Gene3D G3DSA:3.30.70.270 79 178 1.6E-16 T 28-03-2018 ALX04_RS15570 64e585e115c22a22de21af4a42fecb14 433 SUPERFAMILY SSF100879 262 363 1.55E-8 T 28-03-2018 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 ALX04_RS15570 64e585e115c22a22de21af4a42fecb14 433 Pfam PF00817 impB/mucB/samB family 14 167 6.5E-24 T 28-03-2018 IPR001126 UmuC domain GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 ALX04_RS15570 64e585e115c22a22de21af4a42fecb14 433 Pfam PF11798 IMS family HHH motif 183 215 5.2E-7 T 28-03-2018 IPR024728 DNA polymerase type-Y, HhH motif KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5655862|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210 ALX04_RS15570 64e585e115c22a22de21af4a42fecb14 433 SUPERFAMILY SSF56672 11 251 5.96E-47 T 28-03-2018 ALX04_RS15570 64e585e115c22a22de21af4a42fecb14 433 Pfam PF11799 impB/mucB/samB family C-terminal domain 261 372 3.3E-15 T 28-03-2018 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 ALX04_RS02375 620407b90fab7135431a869b3e31c0b7 248 Pfam PF01177 Asp/Glu/Hydantoin racemase 8 228 1.4E-57 T 28-03-2018 IPR015942 Asp/Glu/hydantoin racemase GO:0006807|GO:0036361 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 ALX04_RS02375 620407b90fab7135431a869b3e31c0b7 248 Gene3D G3DSA:3.40.50.1860 122 218 1.7E-19 T 28-03-2018 ALX04_RS02375 620407b90fab7135431a869b3e31c0b7 248 ProSitePatterns PS00923 Aspartate and glutamate racemases signature 1. 81 89 - T 28-03-2018 IPR018187 Asp/Glu racemase, active site 1 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 ALX04_RS02375 620407b90fab7135431a869b3e31c0b7 248 TIGRFAM TIGR00035 asp_race: aspartate racemase 1 234 6.3E-60 T 28-03-2018 IPR004380 Aspartate racemase GO:0006520|GO:0016855 ALX04_RS02375 620407b90fab7135431a869b3e31c0b7 248 SUPERFAMILY SSF53681 4 112 7.03E-28 T 28-03-2018 IPR001920 Asp/Glu racemase GO:0008152|GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 ALX04_RS02375 620407b90fab7135431a869b3e31c0b7 248 SUPERFAMILY SSF53681 123 231 5.89E-23 T 28-03-2018 IPR001920 Asp/Glu racemase GO:0008152|GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 ALX04_RS02375 620407b90fab7135431a869b3e31c0b7 248 Gene3D G3DSA:3.40.50.1860 1 121 5.6E-31 T 28-03-2018 ALX04_RS10460 38c54cb097bbe1c64c5d35086bfd11ab 563 Gene3D G3DSA:2.30.40.10 2 63 9.1E-13 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 ALX04_RS10460 38c54cb097bbe1c64c5d35086bfd11ab 563 Gene3D G3DSA:3.20.20.140 64 248 1.1E-12 T 28-03-2018 ALX04_RS10460 38c54cb097bbe1c64c5d35086bfd11ab 563 Gene3D G3DSA:2.30.40.10 249 344 3.4E-13 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 ALX04_RS10460 38c54cb097bbe1c64c5d35086bfd11ab 563 Pfam PF01979 Amidohydrolase family 56 337 4.8E-22 T 28-03-2018 IPR006680 Amidohydrolase-related GO:0016787 ALX04_RS10460 38c54cb097bbe1c64c5d35086bfd11ab 563 SUPERFAMILY SSF51338 3 59 2.06E-12 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 ALX04_RS10460 38c54cb097bbe1c64c5d35086bfd11ab 563 SUPERFAMILY SSF51338 307 336 2.06E-12 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 ALX04_RS10460 38c54cb097bbe1c64c5d35086bfd11ab 563 TIGRFAM TIGR01178 ade: adenine deaminase 7 551 6.1E-160 T 28-03-2018 IPR006679 Adenine deaminase GO:0000034|GO:0006146 KEGG: 00230+3.5.4.2|MetaCyc: PWY-6610 ALX04_RS10460 38c54cb097bbe1c64c5d35086bfd11ab 563 Hamap MF_01518 Adenine deaminase [ade]. 6 552 36.706 T 28-03-2018 IPR006679 Adenine deaminase GO:0000034|GO:0006146 KEGG: 00230+3.5.4.2|MetaCyc: PWY-6610 ALX04_RS10460 38c54cb097bbe1c64c5d35086bfd11ab 563 Pfam PF13382 Adenine deaminase C-terminal domain 383 548 1.2E-57 T 28-03-2018 IPR026912 Adenine deaminase C-terminal domain KEGG: 00230+3.5.4.2|MetaCyc: PWY-6610 ALX04_RS10460 38c54cb097bbe1c64c5d35086bfd11ab 563 SUPERFAMILY SSF51556 59 307 5.75E-28 T 28-03-2018 IPR032466 Metal-dependent hydrolase ALX04_RS10755 eecad3034639d16a175062e586eba3d5 469 TIGRFAM TIGR01788 Glu-decarb-GAD: glutamate decarboxylase 19 449 6.3E-191 T 28-03-2018 IPR010107 Glutamate decarboxylase GO:0004351|GO:0006536|GO:0030170 KEGG: 00250+4.1.1.15|KEGG: 00410+4.1.1.15|KEGG: 00430+4.1.1.15|KEGG: 00650+4.1.1.15|MetaCyc: PWY-4321 ALX04_RS10755 eecad3034639d16a175062e586eba3d5 469 SUPERFAMILY SSF53383 7 449 4.09E-128 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase ALX04_RS10755 eecad3034639d16a175062e586eba3d5 469 Gene3D G3DSA:3.90.1150.10 327 451 1.6E-26 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 ALX04_RS10755 eecad3034639d16a175062e586eba3d5 469 Gene3D G3DSA:3.40.640.10 68 326 5.3E-29 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 ALX04_RS10755 eecad3034639d16a175062e586eba3d5 469 Pfam PF00282 Pyridoxal-dependent decarboxylase conserved domain 56 383 2.7E-69 T 28-03-2018 IPR002129 Pyridoxal phosphate-dependent decarboxylase GO:0016831|GO:0019752|GO:0030170 ALX04_RS06355 cf77c5f3b5037b872055b5bb7443c1b3 274 Gene3D G3DSA:3.40.190.10 32 145 3.1E-39 T 28-03-2018 ALX04_RS06355 cf77c5f3b5037b872055b5bb7443c1b3 274 Pfam PF03180 NLPA lipoprotein 33 271 3.5E-87 T 28-03-2018 IPR004872 Lipoprotein NlpA family ALX04_RS06355 cf77c5f3b5037b872055b5bb7443c1b3 274 SUPERFAMILY SSF53850 32 271 1.28E-80 T 28-03-2018 ALX04_RS06355 cf77c5f3b5037b872055b5bb7443c1b3 274 Gene3D G3DSA:3.40.190.10 146 271 2.7E-37 T 28-03-2018 ALX04_RS06355 cf77c5f3b5037b872055b5bb7443c1b3 274 PIRSF PIRSF002854 1 273 1.3E-100 T 28-03-2018 IPR004872 Lipoprotein NlpA family ALX04_RS13670 93621d27291f7986f1f25d35fad713c7 430 Pfam PF07498 Rho termination factor, N-terminal domain 9 49 2.3E-9 T 28-03-2018 IPR011112 Rho termination factor, N-terminal GO:0006353 ALX04_RS13670 93621d27291f7986f1f25d35fad713c7 430 SUPERFAMILY SSF50249 54 127 5.63E-22 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold ALX04_RS13670 93621d27291f7986f1f25d35fad713c7 430 Gene3D G3DSA:2.40.50.140 6 121 9.9E-40 T 28-03-2018 ALX04_RS13670 93621d27291f7986f1f25d35fad713c7 430 SUPERFAMILY SSF68912 6 50 4.71E-8 T 28-03-2018 IPR011112 Rho termination factor, N-terminal GO:0006353 ALX04_RS13670 93621d27291f7986f1f25d35fad713c7 430 Gene3D G3DSA:3.40.50.300 122 367 7.6E-48 T 28-03-2018 ALX04_RS13670 93621d27291f7986f1f25d35fad713c7 430 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 159 363 6.7E-19 T 28-03-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 ALX04_RS13670 93621d27291f7986f1f25d35fad713c7 430 TIGRFAM TIGR00767 rho: transcription termination factor Rho 7 415 1.3E-183 T 28-03-2018 IPR004665 Transcription termination factor Rho GO:0003723|GO:0005524|GO:0006353|GO:0008186 ALX04_RS13670 93621d27291f7986f1f25d35fad713c7 430 SMART SM00959 9 51 5.3E-10 T 28-03-2018 IPR011112 Rho termination factor, N-terminal GO:0006353 ALX04_RS13670 93621d27291f7986f1f25d35fad713c7 430 Pfam PF07497 Rho termination factor, RNA-binding domain 55 127 2.5E-29 T 28-03-2018 IPR011113 Rho termination factor, RNA-binding domain GO:0003723|GO:0006353 ALX04_RS13670 93621d27291f7986f1f25d35fad713c7 430 SMART SM00382 170 364 7.7E-7 T 28-03-2018 IPR003593 AAA+ ATPase domain ALX04_RS13670 93621d27291f7986f1f25d35fad713c7 430 SMART SM00357 56 121 7.7E-13 T 28-03-2018 IPR011129 Cold shock domain GO:0003676 ALX04_RS13670 93621d27291f7986f1f25d35fad713c7 430 SUPERFAMILY SSF52540 94 371 5.25E-64 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase ALX04_RS13670 93621d27291f7986f1f25d35fad713c7 430 Hamap MF_01884 Transcription termination factor Rho [rho]. 1 418 198.044 T 28-03-2018 IPR004665 Transcription termination factor Rho GO:0003723|GO:0005524|GO:0006353|GO:0008186 ALX04_RS00250 3d2049223f838a3ef0d53f21444d4547 220 Gene3D G3DSA:1.20.144.10 23 206 4.3E-17 T 28-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase ALX04_RS00250 3d2049223f838a3ef0d53f21444d4547 220 Pfam PF01569 PAP2 superfamily 89 203 2.5E-14 T 28-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase ALX04_RS00250 3d2049223f838a3ef0d53f21444d4547 220 SMART SM00014 84 199 1.6E-10 T 28-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase ALX04_RS00250 3d2049223f838a3ef0d53f21444d4547 220 SUPERFAMILY SSF48317 14 206 2.75E-23 T 28-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase ALX04_RS13645 3251ebe8d96c28584fba7dd0b1e351bf 217 Pfam PF03315 Serine dehydratase beta chain 7 84 9.3E-13 T 28-03-2018 IPR005131 Serine dehydratase beta chain GO:0003941|GO:0006094|GO:0051539 KEGG: 00260+4.3.1.17|KEGG: 00270+4.3.1.17 ALX04_RS13645 3251ebe8d96c28584fba7dd0b1e351bf 217 Gene3D G3DSA:3.30.1330.90 15 140 2.4E-22 T 28-03-2018 IPR029009 Allosteric substrate binding domain Reactome: R-HSA-977347 ALX04_RS13645 3251ebe8d96c28584fba7dd0b1e351bf 217 TIGRFAM TIGR00719 sda_beta: L-serine dehydratase, iron-sulfur-dependent, beta subunit 4 161 3.2E-51 T 28-03-2018 IPR004643 Iron-sulphur-dependent L-serine dehydratase beta subunit GO:0003941|GO:0006094 KEGG: 00260+4.3.1.17|KEGG: 00270+4.3.1.17 ALX04_RS13645 3251ebe8d96c28584fba7dd0b1e351bf 217 SUPERFAMILY SSF143548 21 138 2.62E-29 T 28-03-2018 IPR029009 Allosteric substrate binding domain Reactome: R-HSA-977347 ALX04_RS15010 b5a3813165776b1cff33fd8e5576a88f 157 SUPERFAMILY SSF46785 7 140 4.55E-25 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS15010 b5a3813165776b1cff33fd8e5576a88f 157 Pfam PF01047 MarR family 38 94 1.5E-8 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 ALX04_RS15010 b5a3813165776b1cff33fd8e5576a88f 157 Gene3D G3DSA:1.10.10.10 2 147 9.9E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS15010 b5a3813165776b1cff33fd8e5576a88f 157 SMART SM00347 32 130 1.7E-11 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 ALX04_RS08295 f15bfd1af44ca65f0372ff25a7c3b10a 418 SMART SM00363 350 413 9.2E-4 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 ALX04_RS08295 f15bfd1af44ca65f0372ff25a7c3b10a 418 Gene3D G3DSA:1.10.240.10 222 323 7.9E-37 T 28-03-2018 ALX04_RS08295 f15bfd1af44ca65f0372ff25a7c3b10a 418 SUPERFAMILY SSF52374 1 321 2.49E-107 T 28-03-2018 ALX04_RS08295 f15bfd1af44ca65f0372ff25a7c3b10a 418 Gene3D G3DSA:3.40.50.620 3 221 6.0E-67 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold ALX04_RS08295 f15bfd1af44ca65f0372ff25a7c3b10a 418 TIGRFAM TIGR00234 tyrS: tyrosine--tRNA ligase 2 414 7.5E-129 T 28-03-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 ALX04_RS08295 f15bfd1af44ca65f0372ff25a7c3b10a 418 SUPERFAMILY SSF55174 319 416 6.28E-20 T 28-03-2018 ALX04_RS08295 f15bfd1af44ca65f0372ff25a7c3b10a 418 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 39 49 - T 28-03-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 ALX04_RS08295 f15bfd1af44ca65f0372ff25a7c3b10a 418 Pfam PF00579 tRNA synthetases class I (W and Y) 28 321 2.1E-81 T 28-03-2018 IPR002305 Aminoacyl-tRNA synthetase, class Ic GO:0000166|GO:0004812|GO:0005524|GO:0006418 ALX04_RS08295 f15bfd1af44ca65f0372ff25a7c3b10a 418 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 43 65 1.4E-28 T 28-03-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 ALX04_RS08295 f15bfd1af44ca65f0372ff25a7c3b10a 418 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 158 173 1.4E-28 T 28-03-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 ALX04_RS08295 f15bfd1af44ca65f0372ff25a7c3b10a 418 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 179 201 1.4E-28 T 28-03-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 ALX04_RS08295 f15bfd1af44ca65f0372ff25a7c3b10a 418 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 214 226 1.4E-28 T 28-03-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 ALX04_RS08295 f15bfd1af44ca65f0372ff25a7c3b10a 418 Pfam PF01479 S4 domain 359 393 2.8E-8 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 ALX04_RS08295 f15bfd1af44ca65f0372ff25a7c3b10a 418 Hamap MF_02006 Tyrosine--tRNA ligase [tyrS]. 1 417 42.893 T 28-03-2018 IPR024107 Tyrosine-tRNA ligase, bacterial-type, type 1 GO:0004831 KEGG: 00970+6.1.1.1 ALX04_RS08295 f15bfd1af44ca65f0372ff25a7c3b10a 418 Gene3D G3DSA:3.10.290.10 324 418 2.1E-20 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 ALX04_RS08905 5823681a382faa3063eba31154bff26d 136 SUPERFAMILY SSF56420 2 136 1.96E-37 T 28-03-2018 IPR023635 Peptide deformylase ALX04_RS08905 5823681a382faa3063eba31154bff26d 136 Pfam PF01327 Polypeptide deformylase 16 136 5.7E-28 T 28-03-2018 IPR023635 Peptide deformylase ALX04_RS08905 5823681a382faa3063eba31154bff26d 136 PRINTS PR01576 Peptide deformylase signature 30 59 2.4E-11 T 28-03-2018 IPR023635 Peptide deformylase ALX04_RS08905 5823681a382faa3063eba31154bff26d 136 PRINTS PR01576 Peptide deformylase signature 83 94 2.4E-11 T 28-03-2018 IPR023635 Peptide deformylase ALX04_RS08905 5823681a382faa3063eba31154bff26d 136 PRINTS PR01576 Peptide deformylase signature 113 136 2.4E-11 T 28-03-2018 IPR023635 Peptide deformylase ALX04_RS08905 5823681a382faa3063eba31154bff26d 136 PIRSF PIRSF004749 3 136 1.3E-32 T 28-03-2018 IPR023635 Peptide deformylase ALX04_RS08905 5823681a382faa3063eba31154bff26d 136 Gene3D G3DSA:3.90.45.10 1 136 3.7E-35 T 28-03-2018 IPR023635 Peptide deformylase ALX04_RS02945 df03c43985c5848ef9462791168c24b0 191 PRINTS PR00097 Anthranilate synthase component II signature 47 56 4.3E-29 T 28-03-2018 ALX04_RS02945 df03c43985c5848ef9462791168c24b0 191 PRINTS PR00097 Anthranilate synthase component II signature 164 177 4.3E-29 T 28-03-2018 ALX04_RS02945 df03c43985c5848ef9462791168c24b0 191 PRINTS PR00097 Anthranilate synthase component II signature 99 107 4.3E-29 T 28-03-2018 ALX04_RS02945 df03c43985c5848ef9462791168c24b0 191 PRINTS PR00097 Anthranilate synthase component II signature 2 16 4.3E-29 T 28-03-2018 ALX04_RS02945 df03c43985c5848ef9462791168c24b0 191 PRINTS PR00097 Anthranilate synthase component II signature 74 85 4.3E-29 T 28-03-2018 ALX04_RS02945 df03c43985c5848ef9462791168c24b0 191 PRINTS PR00097 Anthranilate synthase component II signature 119 131 4.3E-29 T 28-03-2018 ALX04_RS02945 df03c43985c5848ef9462791168c24b0 191 Pfam PF00117 Glutamine amidotransferase class-I 3 185 7.6E-41 T 28-03-2018 IPR017926 Glutamine amidotransferase ALX04_RS02945 df03c43985c5848ef9462791168c24b0 191 TIGRFAM TIGR00566 trpG_papA: glutamine amidotransferase of anthranilate synthase or aminodeoxychorismate synthase 3 188 2.6E-55 T 28-03-2018 IPR006221 Anthranilate synthase/para-aminobenzoate synthase like domain GO:0008152 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 ALX04_RS02945 df03c43985c5848ef9462791168c24b0 191 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 74 90 7.5E-7 T 28-03-2018 ALX04_RS02945 df03c43985c5848ef9462791168c24b0 191 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 44 58 7.5E-7 T 28-03-2018 ALX04_RS02945 df03c43985c5848ef9462791168c24b0 191 PRINTS PR00096 Glutamine amidotransferase superfamily signature 164 177 1.7E-12 T 28-03-2018 ALX04_RS02945 df03c43985c5848ef9462791168c24b0 191 PRINTS PR00096 Glutamine amidotransferase superfamily signature 47 56 1.7E-12 T 28-03-2018 ALX04_RS02945 df03c43985c5848ef9462791168c24b0 191 PRINTS PR00096 Glutamine amidotransferase superfamily signature 74 85 1.7E-12 T 28-03-2018 ALX04_RS02945 df03c43985c5848ef9462791168c24b0 191 SUPERFAMILY SSF52317 3 188 1.41E-45 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like ALX04_RS02945 df03c43985c5848ef9462791168c24b0 191 Gene3D G3DSA:3.40.50.880 3 190 5.3E-49 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like ALX04_RS10860 424e0763a7fdefad461c8f63b9bd6b48 221 SUPERFAMILY SSF46785 145 216 1.19E-11 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS10860 424e0763a7fdefad461c8f63b9bd6b48 221 Pfam PF00027 Cyclic nucleotide-binding domain 32 118 1.2E-20 T 28-03-2018 IPR000595 Cyclic nucleotide-binding domain ALX04_RS10860 424e0763a7fdefad461c8f63b9bd6b48 221 Pfam PF13545 Crp-like helix-turn-helix domain 150 217 1.2E-15 T 28-03-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 ALX04_RS10860 424e0763a7fdefad461c8f63b9bd6b48 221 PRINTS PR00034 CRP bacterial regulatory protein HTH signature 170 186 7.0E-7 T 28-03-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 ALX04_RS10860 424e0763a7fdefad461c8f63b9bd6b48 221 PRINTS PR00034 CRP bacterial regulatory protein HTH signature 186 201 7.0E-7 T 28-03-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 ALX04_RS10860 424e0763a7fdefad461c8f63b9bd6b48 221 Gene3D G3DSA:1.10.10.10 146 219 4.8E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS10860 424e0763a7fdefad461c8f63b9bd6b48 221 SMART SM00419 164 213 1.9E-9 T 28-03-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 ALX04_RS10860 424e0763a7fdefad461c8f63b9bd6b48 221 Gene3D G3DSA:2.60.120.10 1 145 7.9E-32 T 28-03-2018 IPR014710 RmlC-like jelly roll fold ALX04_RS10860 424e0763a7fdefad461c8f63b9bd6b48 221 SMART SM00100 12 133 5.7E-20 T 28-03-2018 IPR000595 Cyclic nucleotide-binding domain ALX04_RS10860 424e0763a7fdefad461c8f63b9bd6b48 221 SUPERFAMILY SSF51206 6 142 3.14E-34 T 28-03-2018 IPR018490 Cyclic nucleotide-binding-like ALX04_RS11615 59e2b998e4b49eff9ad46d7ad87dcf9d 670 Pfam PF02272 DHHA1 domain 530 658 9.2E-16 T 28-03-2018 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 ALX04_RS11615 59e2b998e4b49eff9ad46d7ad87dcf9d 670 SUPERFAMILY SSF55073 226 310 7.06E-5 T 28-03-2018 IPR029787 Nucleotide cyclase ALX04_RS11615 59e2b998e4b49eff9ad46d7ad87dcf9d 670 SUPERFAMILY SSF64182 348 654 2.88E-71 T 28-03-2018 ALX04_RS11615 59e2b998e4b49eff9ad46d7ad87dcf9d 670 Pfam PF01368 DHH family 349 508 4.7E-21 T 28-03-2018 IPR001667 DDH domain KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 ALX04_RS11615 59e2b998e4b49eff9ad46d7ad87dcf9d 670 Gene3D G3DSA:3.90.1640.10 327 548 2.6E-48 T 28-03-2018 ALX04_RS11615 59e2b998e4b49eff9ad46d7ad87dcf9d 670 SMART SM00267 151 309 1.5E-4 T 28-03-2018 IPR000160 GGDEF domain ALX04_RS11615 59e2b998e4b49eff9ad46d7ad87dcf9d 670 Gene3D G3DSA:3.30.450.20 76 164 0.0021 T 28-03-2018 ALX04_RS11615 59e2b998e4b49eff9ad46d7ad87dcf9d 670 Gene3D G3DSA:3.30.70.270 165 317 7.4E-7 T 28-03-2018 ALX04_RS11615 59e2b998e4b49eff9ad46d7ad87dcf9d 670 PIRSF PIRSF026583 10 670 8.0E-275 T 28-03-2018 IPR014528 Cyclic-di-AMP phosphodiesterase GdpP/PdeA ALX04_RS15525 c8b71dedcb05be972aedeacdf16b18c4 146 Pfam PF12802 MarR family 33 90 2.5E-6 T 28-03-2018 ALX04_RS15525 c8b71dedcb05be972aedeacdf16b18c4 146 SUPERFAMILY SSF46785 4 143 6.18E-28 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS15525 c8b71dedcb05be972aedeacdf16b18c4 146 SMART SM00347 27 127 9.7E-11 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 ALX04_RS15525 c8b71dedcb05be972aedeacdf16b18c4 146 Gene3D G3DSA:1.10.10.10 18 120 1.1E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS15525 c8b71dedcb05be972aedeacdf16b18c4 146 PRINTS PR00598 Bacterial regulatory protein MarR family signature 117 137 6.8E-10 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 ALX04_RS15525 c8b71dedcb05be972aedeacdf16b18c4 146 PRINTS PR00598 Bacterial regulatory protein MarR family signature 68 83 6.8E-10 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 ALX04_RS15525 c8b71dedcb05be972aedeacdf16b18c4 146 PRINTS PR00598 Bacterial regulatory protein MarR family signature 87 103 6.8E-10 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 ALX04_RS15525 c8b71dedcb05be972aedeacdf16b18c4 146 PRINTS PR00598 Bacterial regulatory protein MarR family signature 51 67 6.8E-10 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 ALX04_RS01995 cee3343eabaf3b0a9cf71779a3797100 202 Pfam PF01810 LysE type translocator 13 195 6.6E-23 T 28-03-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 ALX04_RS02770 5bc75c9ee4f91690c4f7bc0580118947 217 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 43 212 1.4E-21 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 ALX04_RS02770 5bc75c9ee4f91690c4f7bc0580118947 217 Gene3D G3DSA:1.10.3720.10 7 217 1.1E-26 T 28-03-2018 ALX04_RS02770 5bc75c9ee4f91690c4f7bc0580118947 217 SUPERFAMILY SSF161098 22 205 1.7E-33 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 ALX04_RS00380 71f0336cfd92fc8f339c28c3f554e111 209 TIGRFAM TIGR03625 L3_bact: 50S ribosomal protein uL3 5 203 1.9E-80 T 28-03-2018 IPR019927 Ribosomal protein L3, bacterial/organelle-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 ALX04_RS00380 71f0336cfd92fc8f339c28c3f554e111 209 Gene3D G3DSA:4.10.960.10 60 164 1.6E-26 T 28-03-2018 ALX04_RS00380 71f0336cfd92fc8f339c28c3f554e111 209 SUPERFAMILY SSF50447 3 207 6.71E-73 T 28-03-2018 IPR009000 Translation protein, beta-barrel domain ALX04_RS00380 71f0336cfd92fc8f339c28c3f554e111 209 Pfam PF00297 Ribosomal protein L3 100 178 1.1E-15 T 28-03-2018 IPR000597 Ribosomal protein L3 GO:0003735|GO:0005622|GO:0005840|GO:0006412 ALX04_RS00380 71f0336cfd92fc8f339c28c3f554e111 209 Hamap MF_01325_B 50S ribosomal protein L3 [rplC]. 3 206 36.831 T 28-03-2018 IPR019927 Ribosomal protein L3, bacterial/organelle-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 ALX04_RS00605 ab1517f592927c22cc06408f9c1fd084 331 SUPERFAMILY SSF51569 50 327 8.7E-95 T 28-03-2018 ALX04_RS00605 ab1517f592927c22cc06408f9c1fd084 331 Gene3D G3DSA:3.20.20.70 65 326 7.2E-72 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 ALX04_RS00605 ab1517f592927c22cc06408f9c1fd084 331 TIGRFAM TIGR01361 DAHP_synth_Bsub: 3-deoxy-7-phosphoheptulonate synthase 64 321 8.6E-111 T 28-03-2018 IPR006268 Phospho-2-dehydro-3-deoxyheptonate aldolase, subtype 2 GO:0009073|GO:0016832 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164 ALX04_RS00605 ab1517f592927c22cc06408f9c1fd084 331 Pfam PF00793 DAHP synthetase I family 83 327 9.2E-70 T 28-03-2018 IPR006218 DAHP synthetase I/KDSA GO:0009058 KEGG: 00540+2.5.1.55|MetaCyc: PWY-1269|MetaCyc: PWY-7674 ALX04_RS05985 b0d930cc97f298f75fe2247e545f1e88 103 ProSitePatterns PS00194 Thioredoxin family active site. 20 38 - T 28-03-2018 IPR017937 Thioredoxin, conserved site GO:0045454 ALX04_RS05985 b0d930cc97f298f75fe2247e545f1e88 103 PRINTS PR00421 Thioredoxin family signature 19 27 5.0E-6 T 28-03-2018 ALX04_RS05985 b0d930cc97f298f75fe2247e545f1e88 103 PRINTS PR00421 Thioredoxin family signature 67 78 5.0E-6 T 28-03-2018 ALX04_RS05985 b0d930cc97f298f75fe2247e545f1e88 103 PRINTS PR00421 Thioredoxin family signature 27 36 5.0E-6 T 28-03-2018 ALX04_RS05985 b0d930cc97f298f75fe2247e545f1e88 103 SUPERFAMILY SSF52833 5 103 1.47E-33 T 28-03-2018 IPR012336 Thioredoxin-like fold ALX04_RS05985 b0d930cc97f298f75fe2247e545f1e88 103 TIGRFAM TIGR01068 thioredoxin: thioredoxin 7 101 5.1E-34 T 28-03-2018 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 ALX04_RS05985 b0d930cc97f298f75fe2247e545f1e88 103 PIRSF PIRSF000077 1 103 2.8E-37 T 28-03-2018 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 ALX04_RS05985 b0d930cc97f298f75fe2247e545f1e88 103 Pfam PF00085 Thioredoxin 2 101 1.4E-26 T 28-03-2018 IPR013766 Thioredoxin domain GO:0045454 ALX04_RS05985 b0d930cc97f298f75fe2247e545f1e88 103 Gene3D G3DSA:3.40.30.10 1 103 8.6E-32 T 28-03-2018 ALX04_RS07890 e6fe005f0b58b236fcdaae77ef996c3c 510 SUPERFAMILY SSF53927 203 510 6.32E-120 T 28-03-2018 IPR016193 Cytidine deaminase-like GO:0003824 ALX04_RS07890 e6fe005f0b58b236fcdaae77ef996c3c 510 Pfam PF02142 MGS-like domain 14 128 2.3E-26 T 28-03-2018 IPR011607 Methylglyoxal synthase-like domain ALX04_RS07890 e6fe005f0b58b236fcdaae77ef996c3c 510 PIRSF PIRSF000414 1 510 5.6E-200 T 28-03-2018 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 ALX04_RS07890 e6fe005f0b58b236fcdaae77ef996c3c 510 Gene3D G3DSA:3.40.140.20 207 356 5.7E-53 T 28-03-2018 IPR024051 AICAR transformylase domain KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 ALX04_RS07890 e6fe005f0b58b236fcdaae77ef996c3c 510 SMART SM00798 134 443 2.8E-185 T 28-03-2018 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 ALX04_RS07890 e6fe005f0b58b236fcdaae77ef996c3c 510 Gene3D G3DSA:3.40.140.20 357 500 5.1E-45 T 28-03-2018 IPR024051 AICAR transformylase domain KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 ALX04_RS07890 e6fe005f0b58b236fcdaae77ef996c3c 510 Hamap MF_00139 Bifunctional purine biosynthesis protein PurH [purH]. 2 510 43.332 T 28-03-2018 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 ALX04_RS07890 e6fe005f0b58b236fcdaae77ef996c3c 510 SMART SM00851 14 129 6.3E-56 T 28-03-2018 IPR011607 Methylglyoxal synthase-like domain ALX04_RS07890 e6fe005f0b58b236fcdaae77ef996c3c 510 Gene3D G3DSA:3.40.50.1380 1 191 8.6E-70 T 28-03-2018 IPR011607 Methylglyoxal synthase-like domain ALX04_RS07890 e6fe005f0b58b236fcdaae77ef996c3c 510 Pfam PF01808 AICARFT/IMPCHase bienzyme 134 442 3.3E-112 T 28-03-2018 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 ALX04_RS07890 e6fe005f0b58b236fcdaae77ef996c3c 510 SUPERFAMILY SSF52335 2 191 5.76E-67 T 28-03-2018 IPR011607 Methylglyoxal synthase-like domain ALX04_RS07890 e6fe005f0b58b236fcdaae77ef996c3c 510 TIGRFAM TIGR00355 purH: phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 3 510 4.9E-203 T 28-03-2018 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 ALX04_RS15985 16295dfcfa9c67d96c926c36f9d616bc 384 Pfam PF00670 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 188 262 3.2E-8 T 28-03-2018 IPR015878 S-adenosyl-L-homocysteine hydrolase, NAD binding domain KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 ALX04_RS15985 16295dfcfa9c67d96c926c36f9d616bc 384 SMART SM00997 182 330 1.5E-4 T 28-03-2018 IPR015878 S-adenosyl-L-homocysteine hydrolase, NAD binding domain KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 ALX04_RS15985 16295dfcfa9c67d96c926c36f9d616bc 384 Gene3D G3DSA:3.40.50.720 171 373 9.5E-17 T 28-03-2018 ALX04_RS15985 16295dfcfa9c67d96c926c36f9d616bc 384 Gene3D G3DSA:3.40.50.720 29 147 0.28 T 28-03-2018 ALX04_RS15985 16295dfcfa9c67d96c926c36f9d616bc 384 SUPERFAMILY SSF51735 185 258 7.04E-12 T 28-03-2018 IPR016040 NAD(P)-binding domain ALX04_RS02115 4cc432d7434133473cb234cd385691b7 157 Gene3D G3DSA:3.40.50.960 1 154 2.8E-62 T 28-03-2018 IPR002180 Lumazine/riboflavin synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 ALX04_RS02115 4cc432d7434133473cb234cd385691b7 157 SUPERFAMILY SSF52121 4 153 4.06E-59 T 28-03-2018 IPR002180 Lumazine/riboflavin synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 ALX04_RS02115 4cc432d7434133473cb234cd385691b7 157 TIGRFAM TIGR00114 lumazine-synth: 6,7-dimethyl-8-ribityllumazine synthase 13 148 6.0E-54 T 28-03-2018 IPR034964 Lumazine synthase GO:0000906|GO:0009231 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 ALX04_RS02115 4cc432d7434133473cb234cd385691b7 157 Pfam PF00885 6,7-dimethyl-8-ribityllumazine synthase 12 150 1.6E-55 T 28-03-2018 IPR002180 Lumazine/riboflavin synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 ALX04_RS02115 4cc432d7434133473cb234cd385691b7 157 Hamap MF_00178 6,7-dimethyl-8-ribityllumazine synthase [ribH]. 8 153 29.872 T 28-03-2018 IPR034964 Lumazine synthase GO:0000906|GO:0009231 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 ALX04_RS13140 358702e23ade161275728129272c090f 398 SUPERFAMILY SSF52540 18 173 3.5E-11 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase ALX04_RS13140 358702e23ade161275728129272c090f 398 Gene3D G3DSA:3.40.50.300 13 219 1.7E-13 T 28-03-2018 ALX04_RS13140 358702e23ade161275728129272c090f 398 SMART SM00382 41 179 9.2E-4 T 28-03-2018 IPR003593 AAA+ ATPase domain ALX04_RS13140 358702e23ade161275728129272c090f 398 Pfam PF09848 Uncharacterized conserved protein (DUF2075) 43 388 4.2E-101 T 28-03-2018 IPR018647 Domain of unknown function DUF2075 ALX04_RS11145 08665100e32e29a99537a1851324732b 302 SUPERFAMILY SSF53067 1 106 1.81E-9 T 28-03-2018 ALX04_RS11145 08665100e32e29a99537a1851324732b 302 Gene3D G3DSA:3.30.420.40 1 122 3.0E-9 T 28-03-2018 ALX04_RS11145 08665100e32e29a99537a1851324732b 302 SUPERFAMILY SSF53067 113 281 2.59E-36 T 28-03-2018 ALX04_RS11145 08665100e32e29a99537a1851324732b 302 Pfam PF01869 BadF/BadG/BcrA/BcrD ATPase family 5 269 2.6E-21 T 28-03-2018 IPR002731 ATPase, BadF/BadG/BcrA/BcrD type Reactome: R-HSA-446210 ALX04_RS11145 08665100e32e29a99537a1851324732b 302 Gene3D G3DSA:3.30.420.40 123 271 2.3E-32 T 28-03-2018 ALX04_RS06405 bcba0cefcb78cd94540d4fc36f318487 142 Gene3D G3DSA:1.20.5.440 96 139 1.8E-14 T 28-03-2018 ALX04_RS06405 bcba0cefcb78cd94540d4fc36f318487 142 Pfam PF00401 ATP synthase, Delta/Epsilon chain, long alpha-helix domain 94 140 3.0E-15 T 28-03-2018 IPR020547 ATP synthase delta/epsilon subunit, C-terminal domain Reactome: R-HSA-163210|Reactome: R-HSA-8949613 ALX04_RS06405 bcba0cefcb78cd94540d4fc36f318487 142 ProDom PD000944 ATP SYNTHASE ION EPSILON SUBUNIT HYDROLASE CF1 SYNTHESIS CHAIN HYDROGEN 26 91 2.0E-31 T 28-03-2018 IPR020546 ATP synthase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 ALX04_RS06405 bcba0cefcb78cd94540d4fc36f318487 142 Gene3D G3DSA:2.60.15.10 1 95 1.4E-27 T 28-03-2018 IPR020546 ATP synthase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 ALX04_RS06405 bcba0cefcb78cd94540d4fc36f318487 142 Hamap MF_00530 ATP synthase epsilon chain [atpC]. 6 139 23.961 T 28-03-2018 IPR001469 ATP synthase, F1 complex, delta/epsilon subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 ALX04_RS06405 bcba0cefcb78cd94540d4fc36f318487 142 TIGRFAM TIGR01216 ATP_synt_epsi: ATP synthase F1, epsilon subunit 8 140 1.7E-32 T 28-03-2018 IPR001469 ATP synthase, F1 complex, delta/epsilon subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 ALX04_RS06405 bcba0cefcb78cd94540d4fc36f318487 142 SUPERFAMILY SSF46604 93 140 1.05E-7 T 28-03-2018 IPR020547 ATP synthase delta/epsilon subunit, C-terminal domain Reactome: R-HSA-163210|Reactome: R-HSA-8949613 ALX04_RS06405 bcba0cefcb78cd94540d4fc36f318487 142 SUPERFAMILY SSF51344 7 91 3.53E-22 T 28-03-2018 IPR020546 ATP synthase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 ALX04_RS06405 bcba0cefcb78cd94540d4fc36f318487 142 Pfam PF02823 ATP synthase, Delta/Epsilon chain, beta-sandwich domain 8 89 6.6E-27 T 28-03-2018 IPR020546 ATP synthase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 ALX04_RS03685 e9a7bdb23ece616ebe83ca5867e18e28 632 Pfam PF04464 CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase 241 597 6.4E-82 T 28-03-2018 IPR007554 CDP-glycerol glycerophosphotransferase GO:0016020|GO:0047355 ALX04_RS03685 e9a7bdb23ece616ebe83ca5867e18e28 632 SUPERFAMILY SSF53756 320 599 3.37E-17 T 28-03-2018 ALX04_RS04385 9f197c270d70cb017e5e3dca4bf327fa 272 Gene3D G3DSA:3.40.50.300 19 271 1.0E-4 T 28-03-2018 ALX04_RS04385 9f197c270d70cb017e5e3dca4bf327fa 272 Pfam PF03618 Kinase/pyrophosphorylase 6 260 1.7E-96 T 28-03-2018 IPR005177 Bifunctional kinase-pyrophosphorylase GO:0005524|GO:0016772 ALX04_RS04385 9f197c270d70cb017e5e3dca4bf327fa 272 Hamap MF_00921 Putative pyruvate, phosphate dikinase regulatory protein. 4 266 60.693 T 28-03-2018 IPR026565 Putative pyruvate, phosphate dikinase regulatory protein ALX04_RS08110 428dd391d6632760f457d5feac58e94c 393 Pfam PF13527 Acetyltransferase (GNAT) domain 5 129 1.6E-34 T 28-03-2018 ALX04_RS08110 428dd391d6632760f457d5feac58e94c 393 Gene3D G3DSA:3.40.630.30 2 131 1.5E-11 T 28-03-2018 ALX04_RS08110 428dd391d6632760f457d5feac58e94c 393 Gene3D G3DSA:3.30.1050.10 279 387 1.2E-26 T 28-03-2018 IPR003033 SCP2 sterol-binding domain ALX04_RS08110 428dd391d6632760f457d5feac58e94c 393 Gene3D G3DSA:3.40.630.30 132 278 2.5E-30 T 28-03-2018 ALX04_RS08110 428dd391d6632760f457d5feac58e94c 393 SUPERFAMILY SSF55718 285 393 9.03E-23 T 28-03-2018 IPR003033 SCP2 sterol-binding domain ALX04_RS08110 428dd391d6632760f457d5feac58e94c 393 SUPERFAMILY SSF55729 5 284 3.19E-61 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase ALX04_RS08110 428dd391d6632760f457d5feac58e94c 393 Pfam PF13530 Sterol carrier protein domain 177 388 2.6E-42 T 28-03-2018 IPR025559 Enhanced intracellular survival protein domain ALX04_RS00820 c8bee4bfe69971bb5f86a71564c61665 325 Pfam PF03734 L,D-transpeptidase catalytic domain 137 310 1.0E-7 T 28-03-2018 IPR005490 L,D-transpeptidase catalytic domain GO:0016740 ALX04_RS00820 c8bee4bfe69971bb5f86a71564c61665 325 Gene3D G3DSA:2.40.440.10 132 314 5.2E-5 T 28-03-2018 ALX04_RS07125 b3a0c1a2d1b1b2a6ea2e32420b22ac5a 105 SUPERFAMILY SSF109797 13 86 7.32E-7 T 28-03-2018 ALX04_RS07125 b3a0c1a2d1b1b2a6ea2e32420b22ac5a 105 Gene3D G3DSA:1.20.1440.50 12 82 2.5E-11 T 28-03-2018 IPR023130 Ta0600-like domain ALX04_RS11980 8f56fb2e996b92b627b246b3330fdf4a 241 Pfam PF00005 ABC transporter 17 169 1.2E-33 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 ALX04_RS11980 8f56fb2e996b92b627b246b3330fdf4a 241 Gene3D G3DSA:3.40.50.300 1 241 1.6E-58 T 28-03-2018 ALX04_RS11980 8f56fb2e996b92b627b246b3330fdf4a 241 SUPERFAMILY SSF52540 2 219 7.64E-56 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase ALX04_RS11980 8f56fb2e996b92b627b246b3330fdf4a 241 ProSitePatterns PS00211 ABC transporters family signature. 141 155 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 ALX04_RS11980 8f56fb2e996b92b627b246b3330fdf4a 241 SMART SM00382 26 225 7.9E-12 T 28-03-2018 IPR003593 AAA+ ATPase domain ALX04_RS14155 fa1d69143008e1597b6ccbdec407c0d9 323 Pfam PF08545 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III 108 188 5.0E-27 T 28-03-2018 IPR013751 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 ALX04_RS14155 fa1d69143008e1597b6ccbdec407c0d9 323 SUPERFAMILY SSF53901 5 322 3.36E-56 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 ALX04_RS14155 fa1d69143008e1597b6ccbdec407c0d9 323 Gene3D G3DSA:3.40.47.10 5 161 5.8E-31 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 ALX04_RS14155 fa1d69143008e1597b6ccbdec407c0d9 323 Pfam PF08541 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal 239 322 3.4E-24 T 28-03-2018 IPR013747 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III, C-terminal KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 ALX04_RS14155 fa1d69143008e1597b6ccbdec407c0d9 323 Gene3D G3DSA:3.40.47.10 162 322 2.4E-31 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 ALX04_RS14155 fa1d69143008e1597b6ccbdec407c0d9 323 TIGRFAM TIGR00747 fabH: 3-oxoacyl-[acyl-carrier-protein] synthase III 4 322 7.3E-93 T 28-03-2018 IPR004655 3-oxoacyl-[acyl-carrier-protein] synthase 3 GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 ALX04_RS14155 fa1d69143008e1597b6ccbdec407c0d9 323 Hamap MF_01815 3-oxoacyl-[acyl-carrier-protein] synthase 3 [fabH]. 3 323 62.398 T 28-03-2018 IPR004655 3-oxoacyl-[acyl-carrier-protein] synthase 3 GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 ALX04_RS03900 f911f3f4c19e0456da5d24da405e2a17 422 Pfam PF13181 Tetratricopeptide repeat 273 305 0.0012 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 ALX04_RS03900 f911f3f4c19e0456da5d24da405e2a17 422 SMART SM00028 100 133 420.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 ALX04_RS03900 f911f3f4c19e0456da5d24da405e2a17 422 SMART SM00028 32 65 58.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 ALX04_RS03900 f911f3f4c19e0456da5d24da405e2a17 422 SMART SM00028 204 237 0.47 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 ALX04_RS03900 f911f3f4c19e0456da5d24da405e2a17 422 SMART SM00028 238 271 21.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 ALX04_RS03900 f911f3f4c19e0456da5d24da405e2a17 422 SMART SM00028 340 373 45.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 ALX04_RS03900 f911f3f4c19e0456da5d24da405e2a17 422 SMART SM00028 272 305 1.4 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 ALX04_RS03900 f911f3f4c19e0456da5d24da405e2a17 422 Pfam PF13432 Tetratricopeptide repeat 36 91 3.2E-4 T 28-03-2018 ALX04_RS03900 f911f3f4c19e0456da5d24da405e2a17 422 Gene3D G3DSA:1.25.40.10 186 280 1.7E-15 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 ALX04_RS03900 f911f3f4c19e0456da5d24da405e2a17 422 Pfam PF14559 Tetratricopeptide repeat 183 240 9.3E-6 T 28-03-2018 ALX04_RS03900 f911f3f4c19e0456da5d24da405e2a17 422 Gene3D G3DSA:1.25.40.10 355 420 0.0075 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 ALX04_RS03900 f911f3f4c19e0456da5d24da405e2a17 422 Gene3D G3DSA:1.25.40.10 323 354 9.7E-4 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 ALX04_RS03900 f911f3f4c19e0456da5d24da405e2a17 422 Gene3D G3DSA:1.25.40.10 83 185 1.8E-14 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 ALX04_RS03900 f911f3f4c19e0456da5d24da405e2a17 422 Gene3D G3DSA:1.25.40.10 281 322 1.6E-6 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 ALX04_RS03900 f911f3f4c19e0456da5d24da405e2a17 422 SUPERFAMILY SSF48452 24 139 7.09E-27 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 ALX04_RS03900 f911f3f4c19e0456da5d24da405e2a17 422 SUPERFAMILY SSF48452 177 366 7.09E-27 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 ALX04_RS03900 f911f3f4c19e0456da5d24da405e2a17 422 Gene3D G3DSA:1.25.40.10 1 82 2.3E-11 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 ALX04_RS12850 9934be6dfd70fa45487f03df4f842d23 230 SUPERFAMILY SSF81301 33 223 1.32E-51 T 28-03-2018 ALX04_RS12850 9934be6dfd70fa45487f03df4f842d23 230 Pfam PF04607 Region found in RelA / SpoT proteins 68 188 6.0E-35 T 28-03-2018 IPR007685 RelA/SpoT GO:0015969 ALX04_RS12850 9934be6dfd70fa45487f03df4f842d23 230 Gene3D G3DSA:1.10.287.860 174 222 4.2E-15 T 28-03-2018 ALX04_RS12850 9934be6dfd70fa45487f03df4f842d23 230 Gene3D G3DSA:3.30.460.10 21 172 1.6E-32 T 28-03-2018 ALX04_RS12850 9934be6dfd70fa45487f03df4f842d23 230 SMART SM00954 68 191 5.3E-45 T 28-03-2018 IPR007685 RelA/SpoT GO:0015969 ALX04_RS01580 596d3777b404e29a08b4ca4937c3c3c9 460 PIRSF PIRSF006060 1 459 3.6E-80 T 28-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 ALX04_RS01580 596d3777b404e29a08b4ca4937c3c3c9 460 Pfam PF00324 Amino acid permease 15 456 4.8E-122 T 28-03-2018 IPR004841 Amino acid permease/ SLC12A domain GO:0006810|GO:0016020|GO:0055085 ALX04_RS01580 596d3777b404e29a08b4ca4937c3c3c9 460 ProSitePatterns PS00218 Amino acid permeases signature. 40 71 - T 28-03-2018 IPR004840 Amino acid permease, conserved site GO:0006865|GO:0016021|GO:0055085 ALX04_RS03130 f77590ed9fba4bfc6a54521e5f019872 186 Gene3D G3DSA:1.10.10.60 48 175 9.3E-4 T 28-03-2018 ALX04_RS03130 f77590ed9fba4bfc6a54521e5f019872 186 Pfam PF00440 Bacterial regulatory proteins, tetR family 15 57 1.4E-5 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 ALX04_RS03130 f77590ed9fba4bfc6a54521e5f019872 186 Gene3D G3DSA:1.10.10.60 8 47 5.5E-9 T 28-03-2018 ALX04_RS03130 f77590ed9fba4bfc6a54521e5f019872 186 SUPERFAMILY SSF46689 8 72 7.09E-11 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 ALX04_RS12665 4e82b22b56c33bfa8552807736ea25a3 381 Gene3D G3DSA:3.90.1150.10 245 381 2.0E-44 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 ALX04_RS12665 4e82b22b56c33bfa8552807736ea25a3 381 SUPERFAMILY SSF53383 5 377 4.71E-108 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase ALX04_RS12665 4e82b22b56c33bfa8552807736ea25a3 381 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 4 375 4.2E-145 T 28-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 ALX04_RS12665 4e82b22b56c33bfa8552807736ea25a3 381 PIRSF PIRSF001434 1 379 3.0E-136 T 28-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 ALX04_RS12665 4e82b22b56c33bfa8552807736ea25a3 381 Gene3D G3DSA:3.40.640.10 1 244 1.8E-56 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 ALX04_RS01865 10183411810919165ffbf2ca6b854487 768 TIGRFAM TIGR01371 met_syn_B12ind: 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase 8 761 0.0 T 28-03-2018 IPR006276 Cobalamin-independent methionine synthase GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 ALX04_RS01865 10183411810919165ffbf2ca6b854487 768 Pfam PF01717 Cobalamin-independent synthase, Catalytic domain 435 755 2.2E-144 T 28-03-2018 IPR002629 Cobalamin-independent methionine synthase MetE, C-terminal/archaeal GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 ALX04_RS01865 10183411810919165ffbf2ca6b854487 768 Hamap MF_00172 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase [metE]. 3 762 33.986 T 28-03-2018 IPR006276 Cobalamin-independent methionine synthase GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 ALX04_RS01865 10183411810919165ffbf2ca6b854487 768 Pfam PF08267 Cobalamin-independent synthase, N-terminal domain 5 318 1.0E-113 T 28-03-2018 IPR013215 Cobalamin-independent methionine synthase MetE, N-terminal GO:0003871|GO:0008270|GO:0008652 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 ALX04_RS01865 10183411810919165ffbf2ca6b854487 768 SUPERFAMILY SSF51726 400 759 1.57E-110 T 28-03-2018 ALX04_RS01865 10183411810919165ffbf2ca6b854487 768 SUPERFAMILY SSF51726 6 398 1.96E-89 T 28-03-2018 ALX04_RS01865 10183411810919165ffbf2ca6b854487 768 PIRSF PIRSF000382 2 767 0.0 T 28-03-2018 IPR006276 Cobalamin-independent methionine synthase GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 ALX04_RS01865 10183411810919165ffbf2ca6b854487 768 Gene3D G3DSA:3.20.20.210 394 763 1.7E-116 T 28-03-2018 ALX04_RS01865 10183411810919165ffbf2ca6b854487 768 Gene3D G3DSA:3.20.20.210 4 393 6.6E-113 T 28-03-2018 ALX04_RS09265 0ed933eb6cbbda5cf12e07a5eff61eb5 297 Gene3D G3DSA:3.40.50.1980 175 296 6.4E-21 T 28-03-2018 ALX04_RS09265 0ed933eb6cbbda5cf12e07a5eff61eb5 297 Pfam PF01297 Zinc-uptake complex component A periplasmic 35 292 1.3E-45 T 28-03-2018 IPR006127 Periplasmic solute binding protein, ZnuA-like GO:0030001|GO:0046872 ALX04_RS09265 0ed933eb6cbbda5cf12e07a5eff61eb5 297 SUPERFAMILY SSF53807 31 296 5.89E-61 T 28-03-2018 ALX04_RS09265 0ed933eb6cbbda5cf12e07a5eff61eb5 297 PRINTS PR00690 Adhesin family signature 64 77 4.4E-7 T 28-03-2018 IPR006128 Adhesion lipoprotein GO:0007155 ALX04_RS09265 0ed933eb6cbbda5cf12e07a5eff61eb5 297 PRINTS PR00690 Adhesin family signature 32 50 4.4E-7 T 28-03-2018 IPR006128 Adhesion lipoprotein GO:0007155 ALX04_RS09265 0ed933eb6cbbda5cf12e07a5eff61eb5 297 PRINTS PR00690 Adhesin family signature 77 94 4.4E-7 T 28-03-2018 IPR006128 Adhesion lipoprotein GO:0007155 ALX04_RS09265 0ed933eb6cbbda5cf12e07a5eff61eb5 297 Gene3D G3DSA:3.40.50.1980 21 174 7.5E-35 T 28-03-2018 ALX04_RS09180 c54bd01b619fa9423418db17ddbbe3b3 666 SUPERFAMILY SSF52540 4 228 4.52E-68 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase ALX04_RS09180 c54bd01b619fa9423418db17ddbbe3b3 666 ProSitePatterns PS00211 ABC transporters family signature. 144 158 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 ALX04_RS09180 c54bd01b619fa9423418db17ddbbe3b3 666 Gene3D G3DSA:3.40.50.300 1 384 1.4E-65 T 28-03-2018 ALX04_RS09180 c54bd01b619fa9423418db17ddbbe3b3 666 SMART SM00382 32 227 1.4E-14 T 28-03-2018 IPR003593 AAA+ ATPase domain ALX04_RS09180 c54bd01b619fa9423418db17ddbbe3b3 666 Pfam PF02687 FtsX-like permease family 566 659 3.0E-18 T 28-03-2018 IPR003838 ABC transporter permease protein domain GO:0016020 ALX04_RS09180 c54bd01b619fa9423418db17ddbbe3b3 666 Pfam PF00005 ABC transporter 23 171 7.3E-34 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 ALX04_RS09180 c54bd01b619fa9423418db17ddbbe3b3 666 Pfam PF12704 MacB-like periplasmic core domain 265 507 2.5E-14 T 28-03-2018 IPR025857 MacB-like periplasmic core domain ALX04_RS15825 daa6c7095f194585985fc56a2154ac34 384 Pfam PF00999 Sodium/hydrogen exchanger family 9 376 1.1E-79 T 28-03-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 ALX04_RS15825 daa6c7095f194585985fc56a2154ac34 384 Gene3D G3DSA:1.20.91.10 229 312 8.1E-17 T 28-03-2018 ALX04_RS15825 daa6c7095f194585985fc56a2154ac34 384 TIGRFAM TIGR00932 2a37: transporter, monovalent cation:proton antiporter-2 (CPA2) family 11 284 8.0E-72 T 28-03-2018 IPR004771 K+/H+ exchanger GO:0006812|GO:0008324|GO:0016021 ALX04_RS08840 d6191d396971bb62ce84f8467d67d019 455 PIRSF PIRSF006060 8 452 9.3E-62 T 28-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 ALX04_RS08840 d6191d396971bb62ce84f8467d67d019 455 Pfam PF13520 Amino acid permease 36 429 4.8E-34 T 28-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 ALX04_RS13395 e55a839323a5b0394583a150d2147366 716 ProSitePatterns PS00211 ABC transporters family signature. 620 634 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 ALX04_RS13395 e55a839323a5b0394583a150d2147366 716 Pfam PF03412 Peptidase C39 family 5 140 3.5E-46 T 28-03-2018 IPR005074 Peptidase C39, bacteriocin processing GO:0005524|GO:0006508|GO:0008233|GO:0016021 ALX04_RS13395 e55a839323a5b0394583a150d2147366 716 SMART SM00382 507 693 1.0E-14 T 28-03-2018 IPR003593 AAA+ ATPase domain ALX04_RS13395 e55a839323a5b0394583a150d2147366 716 Gene3D G3DSA:3.90.70.10 4 145 1.0E-39 T 28-03-2018 ALX04_RS13395 e55a839323a5b0394583a150d2147366 716 Gene3D G3DSA:3.40.50.300 466 716 6.9E-70 T 28-03-2018 ALX04_RS13395 e55a839323a5b0394583a150d2147366 716 Pfam PF00005 ABC transporter 498 648 2.1E-32 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 ALX04_RS13395 e55a839323a5b0394583a150d2147366 716 SUPERFAMILY SSF90123 155 456 1.44E-63 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 ALX04_RS13395 e55a839323a5b0394583a150d2147366 716 SUPERFAMILY SSF52540 476 715 1.22E-76 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase ALX04_RS13395 e55a839323a5b0394583a150d2147366 716 Pfam PF00664 ABC transporter transmembrane region 166 436 3.4E-61 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 ALX04_RS13395 e55a839323a5b0394583a150d2147366 716 TIGRFAM TIGR01193 bacteriocin_ABC: ABC-type bacteriocin transporter 9 715 0.0 T 28-03-2018 IPR005897 Peptidase C39, ABC-type bacteriocin transporter GO:0008234|GO:0016020|GO:0022885|GO:0043213 ALX04_RS13395 e55a839323a5b0394583a150d2147366 716 Gene3D G3DSA:1.20.1560.10 146 460 3.4E-54 T 28-03-2018 ALX04_RS08085 530fc90567ede96898d6859c6d62386d 188 SUPERFAMILY SSF55811 15 185 1.0E-39 T 28-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 ALX04_RS08085 530fc90567ede96898d6859c6d62386d 188 Gene3D G3DSA:3.90.79.10 12 187 2.5E-35 T 28-03-2018 ALX04_RS08085 530fc90567ede96898d6859c6d62386d 188 ProSitePatterns PS00893 Nudix box signature. 85 106 - T 28-03-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 ALX04_RS08085 530fc90567ede96898d6859c6d62386d 188 Pfam PF00293 NUDIX domain 51 167 7.4E-14 T 28-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 ALX04_RS02845 b8539585a2d80c8c412017ef1217a504 568 TIGRFAM TIGR03599 YloV: DAK2 domain fusion protein YloV 12 568 7.4E-209 T 28-03-2018 IPR019986 DAK2 domain-containing protein YloV ALX04_RS02845 b8539585a2d80c8c412017ef1217a504 568 Pfam PF02734 DAK2 domain 36 200 3.8E-41 T 28-03-2018 IPR004007 DhaL domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 ALX04_RS02845 b8539585a2d80c8c412017ef1217a504 568 Pfam PF13684 Dihydroxyacetone kinase family 242 568 1.5E-117 T 28-03-2018 IPR033470 Uncharacterised protein, DhaK domain ALX04_RS02845 b8539585a2d80c8c412017ef1217a504 568 SMART SM01121 242 568 4.3E-193 T 28-03-2018 IPR033470 Uncharacterised protein, DhaK domain ALX04_RS02845 b8539585a2d80c8c412017ef1217a504 568 SMART SM01120 36 201 7.6E-70 T 28-03-2018 IPR004007 DhaL domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 ALX04_RS02845 b8539585a2d80c8c412017ef1217a504 568 SUPERFAMILY SSF101473 3 202 3.27E-46 T 28-03-2018 IPR004007 DhaL domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 ALX04_RS05550 810757aeaa2d2b9934cf2e1b1fe5a630 319 Pfam PF01795 MraW methylase family 4 313 8.9E-126 T 28-03-2018 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 ALX04_RS05550 810757aeaa2d2b9934cf2e1b1fe5a630 319 Hamap MF_01007 Ribosomal RNA small subunit methyltransferase H [rsmH]. 6 314 38.219 T 28-03-2018 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 ALX04_RS05550 810757aeaa2d2b9934cf2e1b1fe5a630 319 Gene3D G3DSA:1.10.150.170 120 220 9.8E-39 T 28-03-2018 IPR023397 S-adenosyl-L-methionine-dependent methyltransferase, MraW, recognition domain GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 ALX04_RS05550 810757aeaa2d2b9934cf2e1b1fe5a630 319 TIGRFAM TIGR00006 TIGR00006: 16S rRNA (cytosine(1402)-N(4))-methyltransferase 3 313 1.2E-117 T 28-03-2018 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 ALX04_RS05550 810757aeaa2d2b9934cf2e1b1fe5a630 319 Gene3D G3DSA:3.40.50.150 1 119 8.1E-9 T 28-03-2018 ALX04_RS05550 810757aeaa2d2b9934cf2e1b1fe5a630 319 SUPERFAMILY SSF53335 6 116 6.8E-44 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase ALX04_RS05550 810757aeaa2d2b9934cf2e1b1fe5a630 319 SUPERFAMILY SSF53335 218 314 6.8E-44 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase ALX04_RS05550 810757aeaa2d2b9934cf2e1b1fe5a630 319 PIRSF PIRSF004486 1 315 8.0E-107 T 28-03-2018 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 ALX04_RS05550 810757aeaa2d2b9934cf2e1b1fe5a630 319 SUPERFAMILY SSF81799 117 218 1.24E-35 T 28-03-2018 IPR023397 S-adenosyl-L-methionine-dependent methyltransferase, MraW, recognition domain GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 ALX04_RS06260 687b77ad05faaf5eac7f275b6c36dff3 92 Gene3D G3DSA:1.10.10.10 1 90 4.4E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS06260 687b77ad05faaf5eac7f275b6c36dff3 92 SUPERFAMILY SSF46785 4 83 1.0E-25 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS06260 687b77ad05faaf5eac7f275b6c36dff3 92 SMART SM00418 5 79 1.3E-20 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 ALX04_RS06260 687b77ad05faaf5eac7f275b6c36dff3 92 Pfam PF12840 Helix-turn-helix domain 6 62 4.2E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS06260 687b77ad05faaf5eac7f275b6c36dff3 92 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 39 54 3.3E-13 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 ALX04_RS06260 687b77ad05faaf5eac7f275b6c36dff3 92 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 54 69 3.3E-13 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 ALX04_RS06260 687b77ad05faaf5eac7f275b6c36dff3 92 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 7 22 3.3E-13 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 ALX04_RS02385 e70a8e0b5f3620bc2d1df89986c597d0 437 SUPERFAMILY SSF53448 51 338 6.49E-52 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases ALX04_RS02385 e70a8e0b5f3620bc2d1df89986c597d0 437 Pfam PF00535 Glycosyl transferase family 2 65 236 3.7E-28 T 28-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 ALX04_RS02385 e70a8e0b5f3620bc2d1df89986c597d0 437 Gene3D G3DSA:3.90.550.10 38 324 1.1E-53 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases ALX04_RS02095 9cbfbed598c111ddbd0972e53eb5f65e 849 Pfam PF09586 Bacterial membrane protein YfhO 18 832 2.3E-187 T 28-03-2018 IPR018580 Uncharacterised protein family YfhO ALX04_RS00730 f2de9d2fd4e81e3db29a8978cb9d1ba0 549 Pfam PF05598 Transposase domain (DUF772) 45 101 1.3E-11 T 28-03-2018 IPR008490 Transposase InsH, N-terminal ALX04_RS00730 f2de9d2fd4e81e3db29a8978cb9d1ba0 549 Gene3D G3DSA:3.90.350.10 275 491 4.7E-8 T 28-03-2018 IPR014736 Transposase, Tn5-like, core ALX04_RS00730 f2de9d2fd4e81e3db29a8978cb9d1ba0 549 Pfam PF01609 Transposase DDE domain 257 508 7.9E-33 T 28-03-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 ALX04_RS11625 60f14c8a6c9b7e7fcb8faafefd538041 474 SUPERFAMILY SSF48024 8 120 1.57E-36 T 28-03-2018 IPR007693 DNA helicase, DnaB-like, N-terminal GO:0003678|GO:0005524|GO:0006260 ALX04_RS11625 60f14c8a6c9b7e7fcb8faafefd538041 474 Pfam PF03796 DnaB-like helicase C terminal domain 185 464 7.7E-108 T 28-03-2018 IPR007694 DNA helicase, DnaB-like, C-terminal GO:0003678|GO:0005524|GO:0006260 Reactome: R-HSA-2151201 ALX04_RS11625 60f14c8a6c9b7e7fcb8faafefd538041 474 Gene3D G3DSA:3.40.50.300 167 474 1.4E-69 T 28-03-2018 ALX04_RS11625 60f14c8a6c9b7e7fcb8faafefd538041 474 TIGRFAM TIGR00665 DnaB: replicative DNA helicase 10 466 1.8E-175 T 28-03-2018 IPR007692 DNA helicase, DnaB type GO:0003677|GO:0003678|GO:0005524|GO:0006260 ALX04_RS11625 60f14c8a6c9b7e7fcb8faafefd538041 474 Gene3D G3DSA:1.10.860.10 1 151 1.8E-47 T 28-03-2018 IPR016136 DNA helicase DnaB, N-terminal/DNA primase DnaG, C-terminal ALX04_RS11625 60f14c8a6c9b7e7fcb8faafefd538041 474 Pfam PF00772 DnaB-like helicase N terminal domain 10 110 4.1E-34 T 28-03-2018 IPR007693 DNA helicase, DnaB-like, N-terminal GO:0003678|GO:0005524|GO:0006260 ALX04_RS11625 60f14c8a6c9b7e7fcb8faafefd538041 474 SUPERFAMILY SSF52540 183 397 1.88E-47 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase ALX04_RS11625 60f14c8a6c9b7e7fcb8faafefd538041 474 SUPERFAMILY SSF52540 432 457 1.88E-47 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase ALX04_RS06400 80426f10c3b963456a0eafdd26e2302b 438 Gene3D G3DSA:3.65.10.10 21 220 2.6E-48 T 28-03-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 ALX04_RS06400 80426f10c3b963456a0eafdd26e2302b 438 Hamap MF_00111 UDP-N-acetylglucosamine 1-carboxyvinyltransferase [murA]. 1 418 42.725 T 28-03-2018 IPR005750 UDP-N-acetylglucosamine 1-carboxyvinyltransferase GO:0008760|GO:0019277 KEGG: 00520+2.5.1.7|KEGG: 00550+2.5.1.7|MetaCyc: PWY-6386|MetaCyc: PWY-6387 ALX04_RS06400 80426f10c3b963456a0eafdd26e2302b 438 Gene3D G3DSA:3.65.10.10 221 421 1.6E-43 T 28-03-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 ALX04_RS06400 80426f10c3b963456a0eafdd26e2302b 438 Pfam PF00275 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) 7 408 1.4E-103 T 28-03-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 ALX04_RS06400 80426f10c3b963456a0eafdd26e2302b 438 TIGRFAM TIGR01072 murA: UDP-N-acetylglucosamine 1-carboxyvinyltransferase 1 417 7.8E-168 T 28-03-2018 IPR005750 UDP-N-acetylglucosamine 1-carboxyvinyltransferase GO:0008760|GO:0019277 KEGG: 00520+2.5.1.7|KEGG: 00550+2.5.1.7|MetaCyc: PWY-6386|MetaCyc: PWY-6387 ALX04_RS06400 80426f10c3b963456a0eafdd26e2302b 438 SUPERFAMILY SSF55205 1 418 1.59E-136 T 28-03-2018 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 ALX04_RS09805 18ac99f4dc0b3ebe57908ce6435892c0 368 Pfam PF00069 Protein kinase domain 80 221 8.8E-22 T 28-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 ALX04_RS09805 18ac99f4dc0b3ebe57908ce6435892c0 368 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 136 148 - T 28-03-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 ALX04_RS09805 18ac99f4dc0b3ebe57908ce6435892c0 368 SUPERFAMILY SSF56112 66 283 4.37E-31 T 28-03-2018 IPR011009 Protein kinase-like domain ALX04_RS09805 18ac99f4dc0b3ebe57908ce6435892c0 368 SMART SM00220 30 254 1.1E-8 T 28-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 ALX04_RS09805 18ac99f4dc0b3ebe57908ce6435892c0 368 Gene3D G3DSA:1.10.510.10 87 295 1.7E-28 T 28-03-2018 ALX04_RS07420 abbcac732eb4d684c29672812c204c62 294 Gene3D G3DSA:3.40.50.300 4 292 2.3E-75 T 28-03-2018 ALX04_RS07420 abbcac732eb4d684c29672812c204c62 294 TIGRFAM TIGR03709 PPK2_rel_1: polyphosphate:nucleotide phosphotransferase, PPK2 family 5 281 6.7E-115 T 28-03-2018 IPR022300 Polyphosphate:nucleotide phosphotransferase, PPK2 GO:0006797|GO:0016776 ALX04_RS07420 abbcac732eb4d684c29672812c204c62 294 SUPERFAMILY SSF52540 59 262 1.46E-10 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase ALX04_RS07420 abbcac732eb4d684c29672812c204c62 294 PIRSF PIRSF028756 4 293 3.6E-77 T 28-03-2018 IPR016898 Polyphosphate kinase 2 ALX04_RS07420 abbcac732eb4d684c29672812c204c62 294 Pfam PF03976 Polyphosphate kinase 2 (PPK2) 31 264 2.6E-63 T 28-03-2018 IPR022488 Polyphosphate kinase-2-related ALX04_RS07340 7d026d1d7f024c1c72701c08cf91f5f7 169 Pfam PF13411 MerR HTH family regulatory protein 3 68 5.8E-18 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 ALX04_RS07340 7d026d1d7f024c1c72701c08cf91f5f7 169 Gene3D G3DSA:1.10.1660.10 59 132 1.9E-12 T 28-03-2018 ALX04_RS07340 7d026d1d7f024c1c72701c08cf91f5f7 169 Gene3D G3DSA:1.10.1660.10 1 58 3.4E-19 T 28-03-2018 ALX04_RS07340 7d026d1d7f024c1c72701c08cf91f5f7 169 SUPERFAMILY SSF46955 3 117 6.96E-30 T 28-03-2018 IPR009061 Putative DNA-binding domain ALX04_RS07340 7d026d1d7f024c1c72701c08cf91f5f7 169 ProSitePatterns PS00552 MerR-type HTH domain signature. 6 28 - T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 ALX04_RS07340 7d026d1d7f024c1c72701c08cf91f5f7 169 SMART SM00422 3 72 9.3E-21 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 ALX04_RS07340 7d026d1d7f024c1c72701c08cf91f5f7 169 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 4 15 1.9E-6 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 ALX04_RS07340 7d026d1d7f024c1c72701c08cf91f5f7 169 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 39 59 1.9E-6 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 ALX04_RS07340 7d026d1d7f024c1c72701c08cf91f5f7 169 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 15 28 1.9E-6 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 ALX04_RS10795 6ef214dcbcdcd7347b6d2f0d78b858f8 333 Pfam PF04909 Amidohydrolase 54 333 2.0E-44 T 28-03-2018 IPR006680 Amidohydrolase-related GO:0016787 ALX04_RS10795 6ef214dcbcdcd7347b6d2f0d78b858f8 333 Gene3D G3DSA:3.20.20.140 2 333 8.2E-53 T 28-03-2018 ALX04_RS10795 6ef214dcbcdcd7347b6d2f0d78b858f8 333 SUPERFAMILY SSF51556 51 333 3.71E-70 T 28-03-2018 IPR032466 Metal-dependent hydrolase ALX04_RS04940 dbe4845734fe60311ade79dac0e868db 67 Gene3D G3DSA:1.10.10.10 8 67 1.6E-8 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS09515 113bb36604c4e636b6cdd254152addd2 217 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 90 185 1.5E-13 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 ALX04_RS09515 113bb36604c4e636b6cdd254152addd2 217 SUPERFAMILY SSF56784 1 214 1.54E-45 T 28-03-2018 IPR023214 HAD-like domain ALX04_RS09515 113bb36604c4e636b6cdd254152addd2 217 Gene3D G3DSA:3.40.50.1000 77 217 2.1E-26 T 28-03-2018 IPR023214 HAD-like domain ALX04_RS09515 113bb36604c4e636b6cdd254152addd2 217 Pfam PF13419 Haloacid dehalogenase-like hydrolase 5 185 5.2E-27 T 28-03-2018 IPR023214 HAD-like domain ALX04_RS09515 113bb36604c4e636b6cdd254152addd2 217 Gene3D G3DSA:1.10.150.240 15 76 1.2E-5 T 28-03-2018 IPR023198 Phosphoglycolate phosphatase, domain 2 ALX04_RS12315 b95340abf65e81caedeee872fb9098bc 417 PRINTS PR00181 Maltose binding protein signature 370 389 9.1E-6 T 28-03-2018 IPR006060 Maltose/Cyclodextrin ABC transporter, substrate-binding protein GO:0006810 ALX04_RS12315 b95340abf65e81caedeee872fb9098bc 417 PRINTS PR00181 Maltose binding protein signature 134 153 9.1E-6 T 28-03-2018 IPR006060 Maltose/Cyclodextrin ABC transporter, substrate-binding protein GO:0006810 ALX04_RS12315 b95340abf65e81caedeee872fb9098bc 417 PRINTS PR00181 Maltose binding protein signature 77 95 9.1E-6 T 28-03-2018 IPR006060 Maltose/Cyclodextrin ABC transporter, substrate-binding protein GO:0006810 ALX04_RS12315 b95340abf65e81caedeee872fb9098bc 417 Gene3D G3DSA:3.40.190.10 4 192 4.8E-27 T 28-03-2018 ALX04_RS12315 b95340abf65e81caedeee872fb9098bc 417 Pfam PF13416 Bacterial extracellular solute-binding protein 55 350 8.7E-35 T 28-03-2018 ALX04_RS12315 b95340abf65e81caedeee872fb9098bc 417 Gene3D G3DSA:3.40.190.10 203 369 3.1E-10 T 28-03-2018 ALX04_RS12315 b95340abf65e81caedeee872fb9098bc 417 SUPERFAMILY SSF53850 44 407 2.72E-78 T 28-03-2018 ALX04_RS10215 ea2e9b0d994258932e5b9b9302e5707f 624 TIGRFAM TIGR03062 pip_yhgE_Cterm: YhgE/Pip C-terminal domain 415 611 3.0E-55 T 28-03-2018 IPR017501 Phage infection protein, YhgE, C-terminal ALX04_RS10215 ea2e9b0d994258932e5b9b9302e5707f 624 Pfam PF12698 ABC-2 family transporter protein 20 192 1.6E-10 T 28-03-2018 ALX04_RS10215 ea2e9b0d994258932e5b9b9302e5707f 624 TIGRFAM TIGR03061 pip_yhgE_Nterm: YhgE/Pip N-terminal domain 5 166 2.0E-45 T 28-03-2018 IPR017500 Phage infection protein, YhgE, N-terminal ALX04_RS10215 ea2e9b0d994258932e5b9b9302e5707f 624 Gene3D G3DSA:3.40.1710.10 42 208 2.1E-20 T 28-03-2018 ALX04_RS04700 85618782392c1cce527977302e41235b 76 Gene3D G3DSA:1.25.40.290 6 76 7.9E-13 T 28-03-2018 ALX04_RS04700 85618782392c1cce527977302e41235b 76 SUPERFAMILY SSF48371 16 76 4.8E-15 T 28-03-2018 IPR016024 Armadillo-type fold GO:0005488 ALX04_RS04700 85618782392c1cce527977302e41235b 76 Pfam PF08713 DNA alkylation repair enzyme 16 76 6.7E-16 T 28-03-2018 IPR014825 DNA alkylation repair enzyme ALX04_RS00825 0dd4aab1137d71c26c859ef1cf8752ae 325 ProSitePatterns PS00723 Polyprenyl synthases signature 1. 84 98 - T 28-03-2018 IPR033749 Polyprenyl synthetase, conserved site ALX04_RS00825 0dd4aab1137d71c26c859ef1cf8752ae 325 ProSitePatterns PS00444 Polyprenyl synthases signature 2. 207 219 - T 28-03-2018 IPR033749 Polyprenyl synthetase, conserved site ALX04_RS00825 0dd4aab1137d71c26c859ef1cf8752ae 325 SUPERFAMILY SSF48576 2 323 4.89E-72 T 28-03-2018 IPR008949 Isoprenoid synthase domain ALX04_RS00825 0dd4aab1137d71c26c859ef1cf8752ae 325 Pfam PF00348 Polyprenyl synthetase 35 256 7.2E-53 T 28-03-2018 IPR000092 Polyprenyl synthetase GO:0008299 ALX04_RS00825 0dd4aab1137d71c26c859ef1cf8752ae 325 Gene3D G3DSA:1.10.600.10 1 325 6.3E-77 T 28-03-2018 IPR008949 Isoprenoid synthase domain ALX04_RS01055 a36400aff5a12ec8d560990de073caa5 440 Pfam PF04932 O-Antigen ligase 227 362 1.7E-9 T 28-03-2018 IPR007016 O-antigen ligase-related ALX04_RS01570 3ad42f9510d548a0da177c177322b10a 441 TIGRFAM TIGR01197 nramp: metal ion transporter, metal ion (Mn2+/Fe2+) transporter (Nramp) family 28 409 1.5E-95 T 28-03-2018 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-425410 ALX04_RS01570 3ad42f9510d548a0da177c177322b10a 441 PRINTS PR00447 Natural resistance-associated macrophage protein signature 351 368 1.8E-54 T 28-03-2018 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-425410 ALX04_RS01570 3ad42f9510d548a0da177c177322b10a 441 PRINTS PR00447 Natural resistance-associated macrophage protein signature 137 156 1.8E-54 T 28-03-2018 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-425410 ALX04_RS01570 3ad42f9510d548a0da177c177322b10a 441 PRINTS PR00447 Natural resistance-associated macrophage protein signature 323 342 1.8E-54 T 28-03-2018 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-425410 ALX04_RS01570 3ad42f9510d548a0da177c177322b10a 441 PRINTS PR00447 Natural resistance-associated macrophage protein signature 385 404 1.8E-54 T 28-03-2018 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-425410 ALX04_RS01570 3ad42f9510d548a0da177c177322b10a 441 PRINTS PR00447 Natural resistance-associated macrophage protein signature 162 183 1.8E-54 T 28-03-2018 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-425410 ALX04_RS01570 3ad42f9510d548a0da177c177322b10a 441 PRINTS PR00447 Natural resistance-associated macrophage protein signature 214 237 1.8E-54 T 28-03-2018 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-425410 ALX04_RS01570 3ad42f9510d548a0da177c177322b10a 441 PRINTS PR00447 Natural resistance-associated macrophage protein signature 109 135 1.8E-54 T 28-03-2018 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-425410 ALX04_RS01570 3ad42f9510d548a0da177c177322b10a 441 Pfam PF01566 Natural resistance-associated macrophage protein 50 415 5.2E-97 T 28-03-2018 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-425410 ALX04_RS07385 b9dd89afad1ae541e1d9aa82f260cf1d 145 Pfam PF13673 Acetyltransferase (GNAT) domain 23 143 1.5E-18 T 28-03-2018 IPR000182 GNAT domain GO:0008080 ALX04_RS07385 b9dd89afad1ae541e1d9aa82f260cf1d 145 SUPERFAMILY SSF55729 6 144 6.2E-33 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase ALX04_RS07385 b9dd89afad1ae541e1d9aa82f260cf1d 145 Gene3D G3DSA:3.40.630.30 1 145 7.6E-32 T 28-03-2018 ALX04_RS11870 5d0ac85173c4508607ae3b0f6377a0fa 306 SUPERFAMILY SSF46785 1 61 1.43E-8 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS11870 5d0ac85173c4508607ae3b0f6377a0fa 306 Pfam PF08279 HTH domain 6 61 1.6E-10 T 28-03-2018 IPR013196 Helix-turn-helix, type 11 ALX04_RS11870 5d0ac85173c4508607ae3b0f6377a0fa 306 Pfam PF13280 WYL domain 139 302 5.3E-17 T 28-03-2018 IPR026881 WYL domain ALX04_RS11870 5d0ac85173c4508607ae3b0f6377a0fa 306 Gene3D G3DSA:1.10.10.10 1 64 2.8E-11 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS06525 df4f975d896321562a9c3f199c12a5cc 629 Gene3D G3DSA:3.40.50.300 371 626 5.1E-74 T 28-03-2018 ALX04_RS06525 df4f975d896321562a9c3f199c12a5cc 629 Pfam PF00664 ABC transporter transmembrane region 53 339 3.0E-53 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 ALX04_RS06525 df4f975d896321562a9c3f199c12a5cc 629 ProSitePatterns PS00211 ABC transporters family signature. 523 537 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 ALX04_RS06525 df4f975d896321562a9c3f199c12a5cc 629 SUPERFAMILY SSF52540 379 622 1.28E-88 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase ALX04_RS06525 df4f975d896321562a9c3f199c12a5cc 629 Pfam PF00005 ABC transporter 403 551 3.1E-32 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 ALX04_RS06525 df4f975d896321562a9c3f199c12a5cc 629 Gene3D G3DSA:1.20.1560.10 24 370 1.7E-89 T 28-03-2018 ALX04_RS06525 df4f975d896321562a9c3f199c12a5cc 629 SMART SM00382 411 583 7.4E-14 T 28-03-2018 IPR003593 AAA+ ATPase domain ALX04_RS06525 df4f975d896321562a9c3f199c12a5cc 629 SUPERFAMILY SSF90123 39 368 3.27E-83 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 ALX04_RS02325 90dfb03e99f8c54c48cadf2d7747e88c 467 Pfam PF07261 Replication initiation and membrane attachment 323 395 1.4E-10 T 28-03-2018 IPR006343 DnaD domain ALX04_RS02325 90dfb03e99f8c54c48cadf2d7747e88c 467 Gene3D G3DSA:1.10.10.630 317 394 1.6E-8 T 28-03-2018 IPR034829 DnaD-like domain ALX04_RS05240 162811052cce12a28d1873e53fdcbb8f 84 Gene3D G3DSA:1.20.58.110 1 84 3.4E-22 T 28-03-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 ALX04_RS05240 162811052cce12a28d1873e53fdcbb8f 84 ProDom PD004231 RIBOSOMAL S20 30S RRNA-BINDING RNA-BINDING RIBONUCLEOPROTEIN S20P SUBUNIT CHLOROPLAST DIRECT 14 81 1.0E-30 T 28-03-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 ALX04_RS05240 162811052cce12a28d1873e53fdcbb8f 84 TIGRFAM TIGR00029 S20: ribosomal protein bS20 1 81 2.3E-19 T 28-03-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 ALX04_RS05240 162811052cce12a28d1873e53fdcbb8f 84 SUPERFAMILY SSF46992 4 83 6.02E-23 T 28-03-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 ALX04_RS05240 162811052cce12a28d1873e53fdcbb8f 84 Hamap MF_00500 30S ribosomal protein S20 [rpsT]. 1 84 14.702 T 28-03-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 ALX04_RS05240 162811052cce12a28d1873e53fdcbb8f 84 Pfam PF01649 Ribosomal protein S20 4 81 4.3E-23 T 28-03-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 ALX04_RS14000 3ada33fb9e7babfa7435a523f08c89be 532 Pfam PF13520 Amino acid permease 9 430 5.5E-43 T 28-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 ALX04_RS14000 3ada33fb9e7babfa7435a523f08c89be 532 PIRSF PIRSF006060 445 525 470.0 T 28-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 ALX04_RS14000 3ada33fb9e7babfa7435a523f08c89be 532 PIRSF PIRSF006060 1 459 3.0E-69 T 28-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 ALX04_RS08195 023eadcca9546763966bc0158e503533 339 SUPERFAMILY SSF48179 182 309 5.44E-29 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 ALX04_RS08195 023eadcca9546763966bc0158e503533 339 Gene3D G3DSA:3.40.50.720 1 181 6.9E-19 T 28-03-2018 ALX04_RS08195 023eadcca9546763966bc0158e503533 339 Pfam PF02558 Ketopantoate reductase PanE/ApbA 4 143 8.7E-25 T 28-03-2018 IPR013332 Ketopantoate reductase, N-terminal domain GO:0008677|GO:0055114 KEGG: 00052+1.1.1.16|KEGG: 00770+1.1.1.169|MetaCyc: PWY-6654|MetaCyc: PWY-7862 ALX04_RS08195 023eadcca9546763966bc0158e503533 339 Pfam PF08546 Ketopantoate reductase PanE/ApbA C terminal 182 308 1.1E-30 T 28-03-2018 IPR013752 Ketopantoate reductase, C-terminal domain GO:0016491|GO:0050661|GO:0055114 KEGG: 00052+1.1.1.16|KEGG: 00770+1.1.1.169|MetaCyc: PWY-6654|MetaCyc: PWY-7862 ALX04_RS08195 023eadcca9546763966bc0158e503533 339 SUPERFAMILY SSF51735 1 123 2.84E-13 T 28-03-2018 IPR016040 NAD(P)-binding domain ALX04_RS08195 023eadcca9546763966bc0158e503533 339 Gene3D G3DSA:1.10.1040.10 182 323 6.0E-33 T 28-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 ALX04_RS08195 023eadcca9546763966bc0158e503533 339 TIGRFAM TIGR00745 apbA_panE: 2-dehydropantoate 2-reductase 3 310 4.2E-60 T 28-03-2018 IPR003710 Ketopantoate reductase ApbA/PanE GO:0005737|GO:0015940|GO:0016491|GO:0055114 KEGG: 00052+1.1.1.16|KEGG: 00770+1.1.1.169|MetaCyc: PWY-6654|MetaCyc: PWY-7862 ALX04_RS10865 fc08e8f1baa217e018cb3a3627bac011 638 Pfam PF01431 Peptidase family M13 445 635 1.4E-58 T 28-03-2018 IPR018497 Peptidase M13, C-terminal domain GO:0004222|GO:0006508 ALX04_RS10865 fc08e8f1baa217e018cb3a3627bac011 638 Gene3D G3DSA:3.40.390.10 3 239 2.7E-7 T 28-03-2018 IPR024079 Metallopeptidase, catalytic domain GO:0008237 ALX04_RS10865 fc08e8f1baa217e018cb3a3627bac011 638 Gene3D G3DSA:3.40.390.10 311 638 1.8E-90 T 28-03-2018 IPR024079 Metallopeptidase, catalytic domain GO:0008237 ALX04_RS10865 fc08e8f1baa217e018cb3a3627bac011 638 Pfam PF05649 Peptidase family M13 11 388 2.5E-66 T 28-03-2018 IPR008753 Peptidase M13, N-terminal domain GO:0006508 ALX04_RS10865 fc08e8f1baa217e018cb3a3627bac011 638 PRINTS PR00786 Neprilysin metalloprotease (M13) family signature 476 492 1.4E-21 T 28-03-2018 IPR018497 Peptidase M13, C-terminal domain GO:0004222|GO:0006508 ALX04_RS10865 fc08e8f1baa217e018cb3a3627bac011 638 PRINTS PR00786 Neprilysin metalloprotease (M13) family signature 455 467 1.4E-21 T 28-03-2018 IPR018497 Peptidase M13, C-terminal domain GO:0004222|GO:0006508 ALX04_RS10865 fc08e8f1baa217e018cb3a3627bac011 638 PRINTS PR00786 Neprilysin metalloprotease (M13) family signature 546 557 1.4E-21 T 28-03-2018 IPR018497 Peptidase M13, C-terminal domain GO:0004222|GO:0006508 ALX04_RS10865 fc08e8f1baa217e018cb3a3627bac011 638 PRINTS PR00786 Neprilysin metalloprotease (M13) family signature 437 449 1.4E-21 T 28-03-2018 IPR018497 Peptidase M13, C-terminal domain GO:0004222|GO:0006508 ALX04_RS10865 fc08e8f1baa217e018cb3a3627bac011 638 SUPERFAMILY SSF55486 11 638 1.81E-182 T 28-03-2018 ALX04_RS10965 8daa7c3574ab92dac229360a44dfe80a 652 Pfam PF17389 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain 249 575 2.9E-23 T 28-03-2018 IPR035396 Alpha-L-rhamnosidase, six-hairpin glycosidase domain ALX04_RS10965 8daa7c3574ab92dac229360a44dfe80a 652 Gene3D G3DSA:2.60.120.260 8 155 2.0E-50 T 28-03-2018 IPR008979 Galactose-binding domain-like ALX04_RS10965 8daa7c3574ab92dac229360a44dfe80a 652 Gene3D G3DSA:2.60.420.10 574 633 7.8E-6 T 28-03-2018 ALX04_RS10965 8daa7c3574ab92dac229360a44dfe80a 652 Gene3D G3DSA:2.60.120.260 156 243 2.0E-18 T 28-03-2018 IPR008979 Galactose-binding domain-like ALX04_RS10965 8daa7c3574ab92dac229360a44dfe80a 652 SUPERFAMILY SSF48208 249 621 8.38E-44 T 28-03-2018 IPR008928 Six-hairpin glycosidase-like GO:0003824 ALX04_RS10965 8daa7c3574ab92dac229360a44dfe80a 652 Gene3D G3DSA:1.50.10.10 245 573 4.4E-43 T 28-03-2018 ALX04_RS12610 855369f52e66a85a5c4d98203627f73f 448 Pfam PF10009 Uncharacterized protein conserved in bacteria (DUF2252) 56 447 4.5E-129 T 28-03-2018 IPR018721 Protein of unknown function DUF2252 ALX04_RS12610 855369f52e66a85a5c4d98203627f73f 448 Gene3D G3DSA:1.10.510.10 6 176 1.3E-5 T 28-03-2018 ALX04_RS12370 d0eafc4c0354d619d2d22d14a0341c26 651 Pfam PF00367 phosphotransferase system, EIIB 10 40 1.6E-11 T 28-03-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 ALX04_RS12370 d0eafc4c0354d619d2d22d14a0341c26 651 SUPERFAMILY SSF55604 7 80 4.71E-17 T 28-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 ALX04_RS12370 d0eafc4c0354d619d2d22d14a0341c26 651 Pfam PF00358 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 494 617 3.1E-46 T 28-03-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 ALX04_RS12370 d0eafc4c0354d619d2d22d14a0341c26 651 SUPERFAMILY SSF51261 486 637 4.32E-51 T 28-03-2018 IPR011055 Duplicated hybrid motif ALX04_RS12370 d0eafc4c0354d619d2d22d14a0341c26 651 ProSitePatterns PS00371 PTS EIIA domains phosphorylation site signature 1. 556 568 - T 28-03-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 ALX04_RS12370 d0eafc4c0354d619d2d22d14a0341c26 651 Gene3D G3DSA:3.30.1360.60 4 80 7.3E-23 T 28-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 ALX04_RS12370 d0eafc4c0354d619d2d22d14a0341c26 651 TIGRFAM TIGR01996 PTS-II-BC-sucr: PTS system, sucrose-specific IIBC component 2 465 2.9E-195 T 28-03-2018 IPR010973 Phosphotransferase system, sucrose-specific IIBC component GO:0008982|GO:0009401|GO:0016021 ALX04_RS12370 d0eafc4c0354d619d2d22d14a0341c26 651 Gene3D G3DSA:2.70.70.10 483 640 6.9E-55 T 28-03-2018 ALX04_RS12370 d0eafc4c0354d619d2d22d14a0341c26 651 Pfam PF02378 Phosphotransferase system, EIIC 111 412 4.4E-61 T 28-03-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 ALX04_RS12370 d0eafc4c0354d619d2d22d14a0341c26 651 TIGRFAM TIGR00826 EIIB_glc: PTS system, glucose-like IIB component 27 111 1.3E-14 T 28-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 ALX04_RS12370 d0eafc4c0354d619d2d22d14a0341c26 651 ProSitePatterns PS01035 PTS EIIB domains cysteine phosphorylation site signature. 18 35 - T 28-03-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 ALX04_RS12370 d0eafc4c0354d619d2d22d14a0341c26 651 TIGRFAM TIGR00830 PTBA: PTS system, glucose subfamily, IIA component 494 614 1.2E-43 T 28-03-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 ALX04_RS04595 f4b66e9e4ea0f84d6f52efc01b75b171 99 Pfam PF04296 Protein of unknown function (DUF448) 9 81 7.0E-23 T 28-03-2018 IPR007393 Domain of unknown function DUF448 ALX04_RS04595 f4b66e9e4ea0f84d6f52efc01b75b171 99 SUPERFAMILY SSF64376 4 94 2.35E-29 T 28-03-2018 IPR007393 Domain of unknown function DUF448 ALX04_RS04595 f4b66e9e4ea0f84d6f52efc01b75b171 99 Gene3D G3DSA:3.30.1230.10 1 95 4.5E-28 T 28-03-2018 IPR007393 Domain of unknown function DUF448 ALX04_RS02695 56db502f57a13639dcce7146b1c5aa14 92 SUPERFAMILY SSF110324 10 90 4.19E-31 T 28-03-2018 ALX04_RS02695 56db502f57a13639dcce7146b1c5aa14 92 PRINTS PR00063 Ribosomal protein L27 signature 11 35 7.7E-36 T 28-03-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 ALX04_RS02695 56db502f57a13639dcce7146b1c5aa14 92 PRINTS PR00063 Ribosomal protein L27 signature 61 85 7.7E-36 T 28-03-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 ALX04_RS02695 56db502f57a13639dcce7146b1c5aa14 92 PRINTS PR00063 Ribosomal protein L27 signature 36 60 7.7E-36 T 28-03-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 ALX04_RS02695 56db502f57a13639dcce7146b1c5aa14 92 ProDom PD003114 RIBOSOMAL L27 50S RIBONUCLEOPROTEIN CHLOROPLAST MITOCHONDRIAL PEPTIDE 60S TRANSIT PRECURSOR 35 76 6.0E-18 T 28-03-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 ALX04_RS02695 56db502f57a13639dcce7146b1c5aa14 92 Hamap MF_00539 50S ribosomal protein L27 [rpmA]. 8 91 26.31 T 28-03-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 ALX04_RS02695 56db502f57a13639dcce7146b1c5aa14 92 Gene3D G3DSA:2.40.50.100 27 91 2.2E-29 T 28-03-2018 ALX04_RS02695 56db502f57a13639dcce7146b1c5aa14 92 TIGRFAM TIGR00062 L27: ribosomal protein bL27 9 88 7.4E-37 T 28-03-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 ALX04_RS02695 56db502f57a13639dcce7146b1c5aa14 92 Pfam PF01016 Ribosomal L27 protein 10 88 2.2E-33 T 28-03-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 ALX04_RS02695 56db502f57a13639dcce7146b1c5aa14 92 ProSitePatterns PS00831 Ribosomal protein L27 signature. 41 55 - T 28-03-2018 IPR018261 Ribosomal protein L27, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 ALX04_RS03030 df730f09691fe1c3bec96a3e760db7a4 82 SUPERFAMILY SSF47336 1 77 3.14E-19 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain ALX04_RS03030 df730f09691fe1c3bec96a3e760db7a4 82 TIGRFAM TIGR00517 acyl_carrier: acyl carrier protein 4 77 5.4E-22 T 28-03-2018 IPR003231 Acyl carrier protein (ACP) GO:0006633 Reactome: R-HSA-389661|Reactome: R-HSA-611105|Reactome: R-HSA-6799198|Reactome: R-HSA-77289 ALX04_RS03030 df730f09691fe1c3bec96a3e760db7a4 82 Pfam PF00550 Phosphopantetheine attachment site 8 73 1.4E-12 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain ALX04_RS03030 df730f09691fe1c3bec96a3e760db7a4 82 Hamap MF_01217 Acyl carrier protein [acpP]. 5 77 17.328 T 28-03-2018 IPR003231 Acyl carrier protein (ACP) GO:0006633 Reactome: R-HSA-389661|Reactome: R-HSA-611105|Reactome: R-HSA-6799198|Reactome: R-HSA-77289 ALX04_RS03030 df730f09691fe1c3bec96a3e760db7a4 82 Gene3D G3DSA:1.10.1200.10 4 79 4.5E-20 T 28-03-2018 ALX04_RS11100 1430172e74d11b42db76d77cd4eed02b 279 Gene3D G3DSA:3.40.50.720 50 262 8.3E-59 T 28-03-2018 ALX04_RS11100 1430172e74d11b42db76d77cd4eed02b 279 Gene3D G3DSA:3.40.50.720 4 49 5.0E-7 T 28-03-2018 ALX04_RS11100 1430172e74d11b42db76d77cd4eed02b 279 SUPERFAMILY SSF51735 10 255 1.92E-73 T 28-03-2018 IPR016040 NAD(P)-binding domain ALX04_RS11100 1430172e74d11b42db76d77cd4eed02b 279 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 17 253 5.5E-61 T 28-03-2018 ALX04_RS11100 1430172e74d11b42db76d77cd4eed02b 279 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 12 29 1.8E-28 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR ALX04_RS11100 1430172e74d11b42db76d77cd4eed02b 279 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 87 98 1.8E-28 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR ALX04_RS11100 1430172e74d11b42db76d77cd4eed02b 279 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 160 179 1.8E-28 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR ALX04_RS11100 1430172e74d11b42db76d77cd4eed02b 279 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 216 236 1.8E-28 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR ALX04_RS11100 1430172e74d11b42db76d77cd4eed02b 279 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 134 150 1.8E-28 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR ALX04_RS11100 1430172e74d11b42db76d77cd4eed02b 279 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 181 198 1.8E-28 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR ALX04_RS11100 1430172e74d11b42db76d77cd4eed02b 279 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 140 148 1.9E-7 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR ALX04_RS11100 1430172e74d11b42db76d77cd4eed02b 279 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 87 98 1.9E-7 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR ALX04_RS11100 1430172e74d11b42db76d77cd4eed02b 279 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 160 179 1.9E-7 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR ALX04_RS13685 aacafbbaf2f2cf5e3876539594dfca47 234 TIGRFAM TIGR01076 sortase_fam: sortase 87 208 1.5E-18 T 28-03-2018 IPR005754 Sortase family ALX04_RS13685 aacafbbaf2f2cf5e3876539594dfca47 234 Pfam PF04203 Sortase family 89 208 1.9E-22 T 28-03-2018 IPR005754 Sortase family ALX04_RS13685 aacafbbaf2f2cf5e3876539594dfca47 234 Gene3D G3DSA:2.40.260.10 31 228 2.3E-33 T 28-03-2018 IPR023365 Sortase domain ALX04_RS13685 aacafbbaf2f2cf5e3876539594dfca47 234 SUPERFAMILY SSF63817 24 210 3.14E-44 T 28-03-2018 IPR023365 Sortase domain ALX04_RS10045 c0acd9a34d96780dc2eebb2cc8763e5e 366 TIGRFAM TIGR01427 PTS_IIC_fructo: PTS system, Fru family, IIC component 11 336 2.0E-60 T 28-03-2018 IPR006327 Phosphotransferase system, fructose IIC component GO:0005351|GO:0008982|GO:0009401|GO:0016021 ALX04_RS02370 6f22ed846a790df0743cf9eaefe0def7 115 Gene3D G3DSA:1.10.10.10 18 112 1.9E-14 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS02370 6f22ed846a790df0743cf9eaefe0def7 115 SUPERFAMILY SSF46785 9 107 3.51E-30 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS02370 6f22ed846a790df0743cf9eaefe0def7 115 Pfam PF01638 HxlR-like helix-turn-helix 20 107 7.1E-30 T 28-03-2018 IPR002577 Helix-turn-helix, HxlR type ALX04_RS15465 14c2577a682d5516350d9c7f390f8f99 281 Pfam PF03613 PTS system mannose/fructose/sorbose family IID component 9 275 2.9E-90 T 28-03-2018 IPR004704 Phosphotransferase system, mannose/fructose/sorbose family IID component GO:0009401|GO:0016021 ALX04_RS15085 ca3bc40c54f8e48cc6fd6bba5bb4258b 139 SUPERFAMILY SSF55811 5 131 1.12E-25 T 28-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 ALX04_RS15085 ca3bc40c54f8e48cc6fd6bba5bb4258b 139 Pfam PF00293 NUDIX domain 5 120 6.0E-17 T 28-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 ALX04_RS15085 ca3bc40c54f8e48cc6fd6bba5bb4258b 139 Gene3D G3DSA:3.90.79.10 1 139 2.4E-26 T 28-03-2018 ALX04_RS15085 ca3bc40c54f8e48cc6fd6bba5bb4258b 139 PRINTS PR00502 NUDIX hydrolase family signature 46 61 7.0E-5 T 28-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 ALX04_RS15085 ca3bc40c54f8e48cc6fd6bba5bb4258b 139 PRINTS PR00502 NUDIX hydrolase family signature 32 46 7.0E-5 T 28-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 ALX04_RS00920 7f1ebb196fca761861a17e7dd64bfea1 292 Gene3D G3DSA:3.40.50.10490 83 286 6.5E-29 T 28-03-2018 ALX04_RS00920 7f1ebb196fca761861a17e7dd64bfea1 292 SUPERFAMILY SSF53697 105 289 5.46E-35 T 28-03-2018 ALX04_RS00920 7f1ebb196fca761861a17e7dd64bfea1 292 Pfam PF01380 SIS domain 136 265 5.8E-18 T 28-03-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 ALX04_RS00920 7f1ebb196fca761861a17e7dd64bfea1 292 Pfam PF01418 Helix-turn-helix domain, rpiR family 12 79 3.1E-14 T 28-03-2018 IPR000281 Helix-turn-helix protein RpiR GO:0003700|GO:0006355 ALX04_RS00920 7f1ebb196fca761861a17e7dd64bfea1 292 SUPERFAMILY SSF46689 11 80 1.65E-17 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 ALX04_RS00920 7f1ebb196fca761861a17e7dd64bfea1 292 Gene3D G3DSA:1.10.10.10 7 82 4.6E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS00920 7f1ebb196fca761861a17e7dd64bfea1 292 ProSitePatterns PS00356 LacI-type HTH domain signature. 46 64 - T 28-03-2018 ALX04_RS12385 6c285d528ecdf48287701d52a344c647 558 Gene3D G3DSA:3.20.20.80 348 478 4.6E-22 T 28-03-2018 ALX04_RS12385 6c285d528ecdf48287701d52a344c647 558 Gene3D G3DSA:3.90.400.10 106 169 5.5E-29 T 28-03-2018 ALX04_RS12385 6c285d528ecdf48287701d52a344c647 558 SMART SM00642 15 424 4.9E-163 T 28-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 ALX04_RS12385 6c285d528ecdf48287701d52a344c647 558 SUPERFAMILY SSF51011 485 557 8.31E-17 T 28-03-2018 ALX04_RS12385 6c285d528ecdf48287701d52a344c647 558 Gene3D G3DSA:2.60.40.1180 486 558 8.1E-19 T 28-03-2018 ALX04_RS12385 6c285d528ecdf48287701d52a344c647 558 Pfam PF16657 Maltogenic Amylase, C-terminal domain 485 538 1.8E-6 T 28-03-2018 IPR032091 Maltogenic Amylase, C-terminal ALX04_RS12385 6c285d528ecdf48287701d52a344c647 558 Gene3D G3DSA:3.20.20.470 2 105 2.5E-37 T 28-03-2018 ALX04_RS12385 6c285d528ecdf48287701d52a344c647 558 Gene3D G3DSA:3.20.20.470 170 347 2.3E-35 T 28-03-2018 ALX04_RS12385 6c285d528ecdf48287701d52a344c647 558 Pfam PF00128 Alpha amylase, catalytic domain 30 380 2.4E-126 T 28-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 ALX04_RS12385 6c285d528ecdf48287701d52a344c647 558 SUPERFAMILY SSF51445 6 481 1.23E-154 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily ALX04_RS04555 cb9151f471c16de02b2972f1cf6c1b4c 365 Pfam PF02153 Prephenate dehydrogenase 16 273 1.6E-66 T 28-03-2018 IPR003099 Prephenate dehydrogenase GO:0004665|GO:0006571|GO:0008977|GO:0055114 KEGG: 00400+1.3.1.12|KEGG: 00401+1.3.1.12|MetaCyc: PWY-7303 ALX04_RS04555 cb9151f471c16de02b2972f1cf6c1b4c 365 Gene3D G3DSA:1.10.3660.10 182 292 2.7E-22 T 28-03-2018 ALX04_RS04555 cb9151f471c16de02b2972f1cf6c1b4c 365 SUPERFAMILY SSF55021 291 349 1.91E-6 T 28-03-2018 ALX04_RS04555 cb9151f471c16de02b2972f1cf6c1b4c 365 SUPERFAMILY SSF51735 4 169 5.01E-40 T 28-03-2018 IPR016040 NAD(P)-binding domain ALX04_RS04555 cb9151f471c16de02b2972f1cf6c1b4c 365 Gene3D G3DSA:3.30.70.260 293 363 2.6E-6 T 28-03-2018 ALX04_RS04555 cb9151f471c16de02b2972f1cf6c1b4c 365 Gene3D G3DSA:3.40.50.720 2 172 9.7E-22 T 28-03-2018 ALX04_RS04555 cb9151f471c16de02b2972f1cf6c1b4c 365 SUPERFAMILY SSF48179 175 282 3.63E-29 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 ALX04_RS12260 145bf830e308d46892f4123fc280e542 513 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 214 339 2.2E-6 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 ALX04_RS12260 145bf830e308d46892f4123fc280e542 513 Gene3D G3DSA:3.40.50.1220 390 513 2.8E-25 T 28-03-2018 IPR029035 DHS-like NAD/FAD-binding domain ALX04_RS12260 145bf830e308d46892f4123fc280e542 513 SUPERFAMILY SSF52467 393 510 9.16E-26 T 28-03-2018 IPR029035 DHS-like NAD/FAD-binding domain ALX04_RS12260 145bf830e308d46892f4123fc280e542 513 SUPERFAMILY SSF47203 211 348 2.44E-13 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 ALX04_RS12260 145bf830e308d46892f4123fc280e542 513 SUPERFAMILY SSF56645 1 211 9.56E-23 T 28-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 ALX04_RS12260 145bf830e308d46892f4123fc280e542 513 Gene3D G3DSA:2.40.110.10 117 201 2.3E-13 T 28-03-2018 ALX04_RS12260 145bf830e308d46892f4123fc280e542 513 Gene3D G3DSA:1.20.140.10 202 360 5.1E-14 T 28-03-2018 ALX04_RS12260 145bf830e308d46892f4123fc280e542 513 Gene3D G3DSA:1.10.540.10 1 106 2.8E-6 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 ALX04_RS12260 145bf830e308d46892f4123fc280e542 513 Pfam PF00766 Electron transfer flavoprotein FAD-binding domain 394 474 2.1E-16 T 28-03-2018 IPR014731 Electron transfer flavoprotein, alpha subunit, C-terminal Reactome: R-HSA-611105 ALX04_RS04680 203a9ea0ea54f5726ebe3e0c497ff75c 211 Gene3D G3DSA:3.40.1130.10 1 210 6.8E-35 T 28-03-2018 ALX04_RS04680 203a9ea0ea54f5726ebe3e0c497ff75c 211 SUPERFAMILY SSF69593 2 178 3.66E-43 T 28-03-2018 ALX04_RS04680 203a9ea0ea54f5726ebe3e0c497ff75c 211 Pfam PF01553 Acyltransferase 22 141 1.3E-17 T 28-03-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 ALX04_RS04680 203a9ea0ea54f5726ebe3e0c497ff75c 211 SMART SM00563 34 144 9.2E-19 T 28-03-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 ALX04_RS07600 21223314e9ba4fbbc70023c4004201b2 337 Pfam PF03099 Biotin/lipoate A/B protein ligase family 46 155 8.6E-8 T 28-03-2018 IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain GO:0006464 ALX04_RS07600 21223314e9ba4fbbc70023c4004201b2 337 SUPERFAMILY SSF55681 1 249 9.23E-73 T 28-03-2018 ALX04_RS07600 21223314e9ba4fbbc70023c4004201b2 337 Gene3D G3DSA:3.30.930.10 1 251 6.5E-66 T 28-03-2018 ALX04_RS07600 21223314e9ba4fbbc70023c4004201b2 337 SUPERFAMILY SSF82649 250 336 3.35E-25 T 28-03-2018 ALX04_RS07600 21223314e9ba4fbbc70023c4004201b2 337 TIGRFAM TIGR00545 lipoyltrans: lipoyltransferase and lipoate-protein ligase 14 327 1.4E-95 T 28-03-2018 IPR004562 Lipoyltransferase/lipoate-protein ligase GO:0009249 KEGG: 00785+6.3.1.20|Reactome: R-HSA-389661 ALX04_RS07600 21223314e9ba4fbbc70023c4004201b2 337 Gene3D G3DSA:3.30.390.50 252 337 1.6E-25 T 28-03-2018 ALX04_RS07600 21223314e9ba4fbbc70023c4004201b2 337 Pfam PF10437 Bacterial lipoate protein ligase C-terminus 251 335 5.8E-29 T 28-03-2018 IPR019491 Lipoate protein ligase, C-terminal KEGG: 00785+6.3.1.20 ALX04_RS01070 062d275c844da60991eca0a21f19bae9 289 Pfam PF00483 Nucleotidyl transferase 2 238 2.4E-71 T 28-03-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 ALX04_RS01070 062d275c844da60991eca0a21f19bae9 289 SUPERFAMILY SSF53448 1 286 3.38E-94 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases ALX04_RS01070 062d275c844da60991eca0a21f19bae9 289 Gene3D G3DSA:3.90.550.10 1 289 9.2E-73 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases ALX04_RS01070 062d275c844da60991eca0a21f19bae9 289 TIGRFAM TIGR01207 rmlA: glucose-1-phosphate thymidylyltransferase 2 286 3.7E-151 T 28-03-2018 IPR005907 Glucose-1-phosphate thymidylyltransferase, short form GO:0008879|GO:0045226 KEGG: 00521+2.7.7.24|KEGG: 00523+2.7.7.24|KEGG: 00525+2.7.7.24|MetaCyc: PWY-3221|MetaCyc: PWY-6808|MetaCyc: PWY-6942|MetaCyc: PWY-6953|MetaCyc: PWY-6973|MetaCyc: PWY-6974|MetaCyc: PWY-6976|MetaCyc: PWY-7104|MetaCyc: PWY-7301|MetaCyc: PWY-7312|MetaCyc: PWY-7315|MetaCyc: PWY-7316|MetaCyc: PWY-7318|MetaCyc: PWY-7413|MetaCyc: PWY-7414|MetaCyc: PWY-7440|MetaCyc: PWY-7657|MetaCyc: PWY-7688|MetaCyc: PWY-7814 ALX04_RS14455 0cecd63595501fb7080c6932e64d5a60 192 SUPERFAMILY SSF55729 37 186 6.71E-33 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase ALX04_RS14455 0cecd63595501fb7080c6932e64d5a60 192 Gene3D G3DSA:3.40.630.30 39 189 4.4E-32 T 28-03-2018 ALX04_RS14455 0cecd63595501fb7080c6932e64d5a60 192 Pfam PF13673 Acetyltransferase (GNAT) domain 68 166 6.3E-16 T 28-03-2018 IPR000182 GNAT domain GO:0008080 ALX04_RS14455 0cecd63595501fb7080c6932e64d5a60 192 TIGRFAM TIGR01575 rimI: ribosomal-protein-alanine acetyltransferase 47 182 9.1E-35 T 28-03-2018 IPR006464 N-acetyltransferase RimI/Ard1 GO:0006474|GO:0016407 ALX04_RS02755 173fba60149487e30fdfce4f6efa9504 398 SUPERFAMILY SSF54631 251 379 2.54E-25 T 28-03-2018 ALX04_RS02755 173fba60149487e30fdfce4f6efa9504 398 SMART SM00116 319 367 1.9E-6 T 28-03-2018 IPR000644 CBS domain ALX04_RS02755 173fba60149487e30fdfce4f6efa9504 398 SMART SM00116 259 307 6.1E-5 T 28-03-2018 IPR000644 CBS domain ALX04_RS02755 173fba60149487e30fdfce4f6efa9504 398 Gene3D G3DSA:3.40.50.300 2 248 4.5E-76 T 28-03-2018 ALX04_RS02755 173fba60149487e30fdfce4f6efa9504 398 TIGRFAM TIGR01186 proV: glycine betaine/L-proline transport ATP binding subunit 14 372 4.7E-140 T 28-03-2018 IPR005892 Glycine betaine transport ATP-binding subunit GO:0005524|GO:0016020|GO:0031460 ALX04_RS02755 173fba60149487e30fdfce4f6efa9504 398 Pfam PF00571 CBS domain 252 302 2.1E-7 T 28-03-2018 IPR000644 CBS domain ALX04_RS02755 173fba60149487e30fdfce4f6efa9504 398 Pfam PF00571 CBS domain 312 364 9.9E-10 T 28-03-2018 IPR000644 CBS domain ALX04_RS02755 173fba60149487e30fdfce4f6efa9504 398 SMART SM00382 28 214 4.0E-16 T 28-03-2018 IPR003593 AAA+ ATPase domain ALX04_RS02755 173fba60149487e30fdfce4f6efa9504 398 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 ALX04_RS02755 173fba60149487e30fdfce4f6efa9504 398 Pfam PF00005 ABC transporter 20 164 7.1E-33 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 ALX04_RS02755 173fba60149487e30fdfce4f6efa9504 398 Gene3D G3DSA:3.10.580.10 249 391 4.0E-25 T 28-03-2018 ALX04_RS02755 173fba60149487e30fdfce4f6efa9504 398 SUPERFAMILY SSF52540 3 241 2.22E-74 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase ALX04_RS06170 d0375bd585358b10bd43829882123306 222 Pfam PF03775 Septum formation inhibitor MinC, C-terminal domain 104 178 1.1E-13 T 28-03-2018 IPR005526 Septum formation inhibitor MinC, C-terminal GO:0000902 ALX04_RS06170 d0375bd585358b10bd43829882123306 222 Gene3D G3DSA:3.30.750.50 5 93 2.2E-19 T 28-03-2018 ALX04_RS06170 d0375bd585358b10bd43829882123306 222 Gene3D G3DSA:2.160.20.70 94 208 4.3E-17 T 28-03-2018 ALX04_RS06170 d0375bd585358b10bd43829882123306 222 SUPERFAMILY SSF63848 101 193 3.66E-18 T 28-03-2018 IPR005526 Septum formation inhibitor MinC, C-terminal GO:0000902 ALX04_RS07335 a01e47d2f078d06bf5ddea64c411f8e0 115 Pfam PF08818 Domain of unknown function (DU1801) 22 112 8.8E-9 T 28-03-2018 IPR014922 Domain of unknown function DUF1801 ALX04_RS07335 a01e47d2f078d06bf5ddea64c411f8e0 115 SUPERFAMILY SSF159888 9 112 6.02E-17 T 28-03-2018 ALX04_RS03070 7540bde3a98514a6ce6073c1b4ab3b7c 256 Pfam PF03255 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit 2 97 1.0E-33 T 28-03-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 ALX04_RS03070 7540bde3a98514a6ce6073c1b4ab3b7c 256 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 146 155 2.6E-35 T 28-03-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 ALX04_RS03070 7540bde3a98514a6ce6073c1b4ab3b7c 256 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 62 80 2.6E-35 T 28-03-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 ALX04_RS03070 7540bde3a98514a6ce6073c1b4ab3b7c 256 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 118 131 2.6E-35 T 28-03-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 ALX04_RS03070 7540bde3a98514a6ce6073c1b4ab3b7c 256 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 102 115 2.6E-35 T 28-03-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 ALX04_RS03070 7540bde3a98514a6ce6073c1b4ab3b7c 256 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 37 48 2.6E-35 T 28-03-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 ALX04_RS03070 7540bde3a98514a6ce6073c1b4ab3b7c 256 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 83 99 2.6E-35 T 28-03-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 ALX04_RS03070 7540bde3a98514a6ce6073c1b4ab3b7c 256 SUPERFAMILY SSF52096 3 255 5.36E-71 T 28-03-2018 IPR029045 ClpP/crotonase-like domain ALX04_RS03070 7540bde3a98514a6ce6073c1b4ab3b7c 256 Gene3D G3DSA:3.90.226.10 4 253 2.5E-53 T 28-03-2018 ALX04_RS12300 f9e08f0c1b9b2d0dce02c44e3eace34c 339 SUPERFAMILY SSF53822 58 332 5.78E-54 T 28-03-2018 IPR028082 Periplasmic binding protein-like I ALX04_RS12300 f9e08f0c1b9b2d0dce02c44e3eace34c 339 SUPERFAMILY SSF47413 1 59 1.19E-16 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 ALX04_RS12300 f9e08f0c1b9b2d0dce02c44e3eace34c 339 ProSitePatterns PS00356 LacI-type HTH domain signature. 4 22 - T 28-03-2018 ALX04_RS12300 f9e08f0c1b9b2d0dce02c44e3eace34c 339 Pfam PF00356 Bacterial regulatory proteins, lacI family 3 48 1.9E-17 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 ALX04_RS12300 f9e08f0c1b9b2d0dce02c44e3eace34c 339 Gene3D G3DSA:1.10.260.40 2 56 3.2E-20 T 28-03-2018 ALX04_RS12300 f9e08f0c1b9b2d0dce02c44e3eace34c 339 Pfam PF13377 Periplasmic binding protein-like domain 174 332 6.2E-18 T 28-03-2018 ALX04_RS12300 f9e08f0c1b9b2d0dce02c44e3eace34c 339 Gene3D G3DSA:3.40.50.2300 179 312 1.7E-26 T 28-03-2018 ALX04_RS12300 f9e08f0c1b9b2d0dce02c44e3eace34c 339 Gene3D G3DSA:3.40.50.2300 57 178 3.4E-27 T 28-03-2018 ALX04_RS12300 f9e08f0c1b9b2d0dce02c44e3eace34c 339 SMART SM00354 1 71 6.9E-26 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 ALX04_RS03405 25ceb4f1a29711045956cebe671fe743 113 TIGRFAM TIGR03544 DivI1A_domain: DivIVA domain 6 39 1.8E-16 T 28-03-2018 IPR019933 DivIVA domain ALX04_RS03405 25ceb4f1a29711045956cebe671fe743 113 Pfam PF05103 DivIVA protein 7 65 2.0E-19 T 28-03-2018 IPR007793 DivIVA family ALX04_RS03405 25ceb4f1a29711045956cebe671fe743 113 PIRSF PIRSF029938 1 105 1.0E-42 T 28-03-2018 IPR011229 Cell cycle protein GpsB ALX04_RS03405 25ceb4f1a29711045956cebe671fe743 113 Hamap MF_02011 Cell cycle protein GpsB [gpsB]. 1 101 23.763 T 28-03-2018 IPR011229 Cell cycle protein GpsB ALX04_RS03405 25ceb4f1a29711045956cebe671fe743 113 Gene3D G3DSA:1.20.5.400 26 69 2.5E-5 T 28-03-2018 ALX04_RS11595 871ce240e6bc56c255d9d215388311ca 853 Pfam PF00521 DNA gyrase/topoisomerase IV, subunit A 35 474 7.6E-163 T 28-03-2018 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 ALX04_RS11595 871ce240e6bc56c255d9d215388311ca 853 Gene3D G3DSA:3.30.1360.40 239 335 8.8E-36 T 28-03-2018 IPR024946 Arginine repressor C-terminal-like domain Reactome: R-HSA-4615885 ALX04_RS11595 871ce240e6bc56c255d9d215388311ca 853 SUPERFAMILY SSF56719 34 489 8.11E-183 T 28-03-2018 IPR013760 DNA topoisomerase, type IIA-like domain GO:0003918|GO:0005524 Reactome: R-HSA-4615885 ALX04_RS11595 871ce240e6bc56c255d9d215388311ca 853 SUPERFAMILY SSF101904 502 818 9.81E-107 T 28-03-2018 IPR035516 DNA gyrase/topoisomerase IV, subunit A, C-terminal ALX04_RS11595 871ce240e6bc56c255d9d215388311ca 853 SMART SM00434 14 467 6.6E-285 T 28-03-2018 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 ALX04_RS11595 871ce240e6bc56c255d9d215388311ca 853 Gene3D G3DSA:2.120.10.90 500 811 2.3E-119 T 28-03-2018 ALX04_RS11595 871ce240e6bc56c255d9d215388311ca 853 Hamap MF_01897 DNA gyrase subunit A [gyrA]. 3 812 24.661 T 28-03-2018 IPR005743 DNA gyrase, subunit A GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 ALX04_RS11595 871ce240e6bc56c255d9d215388311ca 853 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 615 659 2.2E-10 T 28-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 ALX04_RS11595 871ce240e6bc56c255d9d215388311ca 853 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 764 810 3.2E-11 T 28-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 ALX04_RS11595 871ce240e6bc56c255d9d215388311ca 853 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 663 709 1.2E-12 T 28-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 ALX04_RS11595 871ce240e6bc56c255d9d215388311ca 853 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 557 605 1.4E-11 T 28-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 ALX04_RS11595 871ce240e6bc56c255d9d215388311ca 853 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 714 760 1.5E-11 T 28-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 ALX04_RS11595 871ce240e6bc56c255d9d215388311ca 853 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 510 553 1.4E-10 T 28-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 ALX04_RS11595 871ce240e6bc56c255d9d215388311ca 853 Gene3D G3DSA:3.90.199.10 37 216 3.1E-86 T 28-03-2018 IPR013758 DNA topoisomerase, type IIA, subunit A/ C-terminal, alpha-beta GO:0003677|GO:0003918|GO:0005524|GO:0006259|GO:0006265 Reactome: R-HSA-4615885 ALX04_RS11595 871ce240e6bc56c255d9d215388311ca 853 TIGRFAM TIGR01063 gyrA: DNA gyrase, A subunit 11 810 0.0 T 28-03-2018 ALX04_RS11595 871ce240e6bc56c255d9d215388311ca 853 Gene3D G3DSA:1.10.268.10 347 489 5.8E-54 T 28-03-2018 IPR013757 Type IIA DNA topoisomerase subunit A, alpha-helical domain GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 ALX04_RS08925 652b2b1b98e076775905f917e86befb8 419 Gene3D G3DSA:1.20.1600.10 164 413 3.0E-11 T 28-03-2018 ALX04_RS08925 652b2b1b98e076775905f917e86befb8 419 Pfam PF00746 LPXTG cell wall anchor motif 374 410 7.6E-7 T 28-03-2018 IPR019948 Gram-positive LPXTG cell wall anchor ALX04_RS08925 652b2b1b98e076775905f917e86befb8 419 Gene3D G3DSA:1.10.287.620 20 114 0.028 T 28-03-2018 ALX04_RS08925 652b2b1b98e076775905f917e86befb8 419 TIGRFAM TIGR01167 LPXTG_anchor: LPXTG cell wall anchor domain 380 411 1.4E-7 T 28-03-2018 ALX04_RS13525 0cb7671798b41bbc4326be01a4c465da 394 Gene3D G3DSA:1.20.1250.20 5 200 1.7E-27 T 28-03-2018 ALX04_RS13525 0cb7671798b41bbc4326be01a4c465da 394 SUPERFAMILY SSF103473 8 391 4.05E-54 T 28-03-2018 IPR020846 Major facilitator superfamily domain ALX04_RS13525 0cb7671798b41bbc4326be01a4c465da 394 TIGRFAM TIGR00710 efflux_Bcr_CflA: drug resistance transporter, Bcr/CflA subfamily 11 383 3.7E-65 T 28-03-2018 IPR004812 Drug resistance transporter Bcr/CmlA subfamily GO:0005215|GO:0006810|GO:0016021 ALX04_RS13525 0cb7671798b41bbc4326be01a4c465da 394 Pfam PF07690 Major Facilitator Superfamily 23 349 4.3E-37 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 ALX04_RS13525 0cb7671798b41bbc4326be01a4c465da 394 Gene3D G3DSA:1.20.1250.20 201 394 2.1E-14 T 28-03-2018 ALX04_RS03815 ce73e4ba3ad880ab2c1922c6df21fb80 382 SUPERFAMILY SSF51726 8 381 1.7E-53 T 28-03-2018 ALX04_RS03815 ce73e4ba3ad880ab2c1922c6df21fb80 382 Gene3D G3DSA:3.20.20.210 1 382 8.8E-60 T 28-03-2018 ALX04_RS03560 17914ddda51a310ad18d224f4ab27342 164 ProSitePatterns PS00893 Nudix box signature. 39 60 - T 28-03-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 ALX04_RS03560 17914ddda51a310ad18d224f4ab27342 164 SUPERFAMILY SSF55811 3 156 2.98E-21 T 28-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 ALX04_RS03560 17914ddda51a310ad18d224f4ab27342 164 Pfam PF00293 NUDIX domain 4 125 1.6E-14 T 28-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 ALX04_RS03560 17914ddda51a310ad18d224f4ab27342 164 Gene3D G3DSA:3.90.79.10 1 150 1.3E-18 T 28-03-2018 ALX04_RS12490 d0a81537ae17d181af76f75e23c806ca 506 Gene3D G3DSA:3.40.50.300 5 248 8.1E-33 T 28-03-2018 ALX04_RS12490 d0a81537ae17d181af76f75e23c806ca 506 SUPERFAMILY SSF52540 3 178 2.53E-28 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase ALX04_RS12490 d0a81537ae17d181af76f75e23c806ca 506 ProSitePatterns PS00211 ABC transporters family signature. 382 396 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 ALX04_RS12490 d0a81537ae17d181af76f75e23c806ca 506 Pfam PF00005 ABC transporter 286 410 6.7E-16 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 ALX04_RS12490 d0a81537ae17d181af76f75e23c806ca 506 Pfam PF00005 ABC transporter 27 64 1.7E-7 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 ALX04_RS12490 d0a81537ae17d181af76f75e23c806ca 506 SMART SM00382 28 151 1.4E-4 T 28-03-2018 IPR003593 AAA+ ATPase domain ALX04_RS12490 d0a81537ae17d181af76f75e23c806ca 506 SMART SM00382 293 458 1.3E-10 T 28-03-2018 IPR003593 AAA+ ATPase domain ALX04_RS12490 d0a81537ae17d181af76f75e23c806ca 506 Gene3D G3DSA:3.40.50.300 261 468 1.8E-37 T 28-03-2018 ALX04_RS12490 d0a81537ae17d181af76f75e23c806ca 506 SUPERFAMILY SSF52540 273 456 1.58E-35 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase ALX04_RS08225 82262121ffed6046dd82b382e689239a 1039 Pfam PF03382 Mycoplasma protein of unknown function, DUF285 394 473 3.4E-8 T 28-03-2018 IPR005046 Protein of unknown function DUF285 ALX04_RS08225 82262121ffed6046dd82b382e689239a 1039 Pfam PF03382 Mycoplasma protein of unknown function, DUF285 279 388 1.8E-13 T 28-03-2018 IPR005046 Protein of unknown function DUF285 ALX04_RS08225 82262121ffed6046dd82b382e689239a 1039 Gene3D G3DSA:2.60.40.10 702 783 3.9E-8 T 28-03-2018 IPR013783 Immunoglobulin-like fold ALX04_RS08225 82262121ffed6046dd82b382e689239a 1039 TIGRFAM TIGR02167 Liste_lipo_26: bacterial surface protein 26-residue repeat 339 354 7.4E-4 T 28-03-2018 IPR011889 Bacterial surface protein 26-residue repeat ALX04_RS08225 82262121ffed6046dd82b382e689239a 1039 TIGRFAM TIGR02167 Liste_lipo_26: bacterial surface protein 26-residue repeat 306 330 1.0E-8 T 28-03-2018 IPR011889 Bacterial surface protein 26-residue repeat ALX04_RS08225 82262121ffed6046dd82b382e689239a 1039 TIGRFAM TIGR02167 Liste_lipo_26: bacterial surface protein 26-residue repeat 439 455 1.7E-4 T 28-03-2018 IPR011889 Bacterial surface protein 26-residue repeat ALX04_RS08225 82262121ffed6046dd82b382e689239a 1039 TIGRFAM TIGR03715 KxYKxGKxW: KxYKxGKxW signal peptide 5 27 8.8E-10 T 28-03-2018 IPR022263 KxYKxGKxW signal peptide ALX04_RS08225 82262121ffed6046dd82b382e689239a 1039 Gene3D G3DSA:3.80.10.10 126 519 1.6E-15 T 28-03-2018 IPR032675 Leucine-rich repeat domain, L domain-like ALX04_RS08225 82262121ffed6046dd82b382e689239a 1039 Gene3D G3DSA:2.60.40.10 790 865 3.2E-13 T 28-03-2018 IPR013783 Immunoglobulin-like fold ALX04_RS08225 82262121ffed6046dd82b382e689239a 1039 Gene3D G3DSA:2.60.40.10 622 695 2.7E-5 T 28-03-2018 IPR013783 Immunoglobulin-like fold ALX04_RS08225 82262121ffed6046dd82b382e689239a 1039 Gene3D G3DSA:2.60.40.10 543 621 5.0E-4 T 28-03-2018 IPR013783 Immunoglobulin-like fold ALX04_RS08225 82262121ffed6046dd82b382e689239a 1039 Pfam PF07523 Bacterial Ig-like domain (group 3) 717 776 1.9E-6 T 28-03-2018 IPR022038 Bacterial Ig-like domain ALX04_RS08225 82262121ffed6046dd82b382e689239a 1039 Pfam PF07523 Bacterial Ig-like domain (group 3) 792 861 9.2E-15 T 28-03-2018 IPR022038 Bacterial Ig-like domain ALX04_RS08225 82262121ffed6046dd82b382e689239a 1039 Pfam PF07523 Bacterial Ig-like domain (group 3) 546 617 3.7E-6 T 28-03-2018 IPR022038 Bacterial Ig-like domain ALX04_RS08225 82262121ffed6046dd82b382e689239a 1039 Pfam PF07523 Bacterial Ig-like domain (group 3) 627 692 5.7E-16 T 28-03-2018 IPR022038 Bacterial Ig-like domain ALX04_RS08225 82262121ffed6046dd82b382e689239a 1039 SUPERFAMILY SSF52058 300 477 4.08E-12 T 28-03-2018 IPR032675 Leucine-rich repeat domain, L domain-like ALX04_RS13735 9eda3248bd7df94359ef9abfbd84db18 659 Hamap MF_01522 Low affinity potassium transport system protein kup [kup]. 7 647 27.659 T 28-03-2018 IPR023051 Potassium uptake protein, low affinity, Kup ALX04_RS13735 9eda3248bd7df94359ef9abfbd84db18 659 Pfam PF02705 K+ potassium transporter 16 551 8.7E-163 T 28-03-2018 IPR003855 Potassium transporter GO:0015079|GO:0016020|GO:0071805 ALX04_RS02330 a2aaacf7ff0c30b6f42f71b3b9bed811 311 Pfam PF01695 IstB-like ATP binding protein 112 266 4.2E-9 T 28-03-2018 IPR002611 IstB-like ATP-binding protein GO:0005524 ALX04_RS02330 a2aaacf7ff0c30b6f42f71b3b9bed811 311 SUPERFAMILY SSF52540 126 268 1.87E-17 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase ALX04_RS02330 a2aaacf7ff0c30b6f42f71b3b9bed811 311 Gene3D G3DSA:3.40.50.300 102 300 2.1E-14 T 28-03-2018 ALX04_RS02330 a2aaacf7ff0c30b6f42f71b3b9bed811 311 Pfam PF07319 Primosomal protein DnaI N-terminus 1 93 4.1E-31 T 28-03-2018 IPR009928 Primosomal DnaI, N-terminal ALX04_RS09490 a8360974f2526ef84ad52f5fad238ffe 347 Pfam PF11797 Protein of unknown function C-terminal (DUF3324) 163 299 6.1E-44 T 28-03-2018 IPR021759 Domain of unknown function DUF3324, C-terminal ALX04_RS09490 a8360974f2526ef84ad52f5fad238ffe 347 ProSitePatterns PS00602 Fructose-bisphosphate aldolase class-II signature 1. 171 184 - T 28-03-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 ALX04_RS09490 a8360974f2526ef84ad52f5fad238ffe 347 Pfam PF06030 Bacterial protein of unknown function (DUF916) 34 152 5.5E-35 T 28-03-2018 IPR010317 Protein of unknown function DUF916, cell surface putative ALX04_RS09490 a8360974f2526ef84ad52f5fad238ffe 347 Gene3D G3DSA:2.60.40.1710 43 211 1.1E-6 T 28-03-2018 ALX04_RS05115 23e2ab7b805940f4e5b22e999a524525 483 Pfam PF14667 Polysaccharide biosynthesis C-terminal domain 338 462 1.1E-10 T 28-03-2018 IPR029303 Polysaccharide biosynthesis protein, C-terminal domain ALX04_RS05115 23e2ab7b805940f4e5b22e999a524525 483 Pfam PF01943 Polysaccharide biosynthesis protein 17 282 2.4E-11 T 28-03-2018 IPR002797 Polysaccharide biosynthesis protein GO:0016020 ALX04_RS14615 8a5d834ae66a4f56133572aaf3c427b0 306 TIGRFAM TIGR01099 galU: UTP--glucose-1-phosphate uridylyltransferase 4 264 9.3E-114 T 28-03-2018 IPR005771 UTP--glucose-1-phosphate uridylyltransferase, bacterial/archaeal-type GO:0003983|GO:0006011 KEGG: 00040+2.7.7.9|KEGG: 00052+2.7.7.9|KEGG: 00500+2.7.7.9|KEGG: 00520+2.7.7.9|MetaCyc: PWY-3801|MetaCyc: PWY-6527|MetaCyc: PWY-7238|MetaCyc: PWY-7343|MetaCyc: PWY-7817 ALX04_RS14615 8a5d834ae66a4f56133572aaf3c427b0 306 SUPERFAMILY SSF53448 2 268 3.6E-66 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases ALX04_RS14615 8a5d834ae66a4f56133572aaf3c427b0 306 Gene3D G3DSA:3.90.550.10 1 291 8.5E-62 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases ALX04_RS14615 8a5d834ae66a4f56133572aaf3c427b0 306 Pfam PF00483 Nucleotidyl transferase 6 257 1.5E-33 T 28-03-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 ALX04_RS08150 9f7c96221d36f6c9f267bb46d2960b35 480 ProSitePatterns PS00653 Glycosyl hydrolases family 1 N-terminal signature. 11 25 - T 28-03-2018 IPR033132 Glycosyl hydrolases family 1, N-terminal conserved site ALX04_RS08150 9f7c96221d36f6c9f267bb46d2960b35 480 Gene3D G3DSA:3.20.20.80 1 480 1.6E-153 T 28-03-2018 ALX04_RS08150 9f7c96221d36f6c9f267bb46d2960b35 480 Pfam PF00232 Glycosyl hydrolase family 1 7 476 1.5E-132 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 ALX04_RS08150 9f7c96221d36f6c9f267bb46d2960b35 480 PRINTS PR00131 Glycosyl hydrolase family 1 signature 308 322 1.2E-16 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 ALX04_RS08150 9f7c96221d36f6c9f267bb46d2960b35 480 PRINTS PR00131 Glycosyl hydrolase family 1 signature 416 433 1.2E-16 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 ALX04_RS08150 9f7c96221d36f6c9f267bb46d2960b35 480 PRINTS PR00131 Glycosyl hydrolase family 1 signature 373 381 1.2E-16 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 ALX04_RS08150 9f7c96221d36f6c9f267bb46d2960b35 480 PRINTS PR00131 Glycosyl hydrolase family 1 signature 441 453 1.2E-16 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 ALX04_RS08150 9f7c96221d36f6c9f267bb46d2960b35 480 PRINTS PR00131 Glycosyl hydrolase family 1 signature 394 405 1.2E-16 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 ALX04_RS08150 9f7c96221d36f6c9f267bb46d2960b35 480 SUPERFAMILY SSF51445 6 473 1.81E-164 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily ALX04_RS11420 3747c8d5fcd63ebb8e5df9417f974edf 125 ProDom PD015842 PTS IIA COMPONENT GLUCITOL/SORBITOL-SPECIFIC SYSTEM ENZYME TRANSFERASE SYSTEM PHOSPHOTRANSFERASE EIIA 11 121 9.0E-60 T 28-03-2018 IPR004716 Phosphotransferase system, glucitol/sorbitol-specific IIA component GO:0005737|GO:0008982|GO:0009401 KEGG: 00051+2.7.1.198|KEGG: 00710+2.7.1.19|MetaCyc: PWY-5723 ALX04_RS11420 3747c8d5fcd63ebb8e5df9417f974edf 125 SUPERFAMILY SSF141530 8 123 1.12E-34 T 28-03-2018 IPR004716 Phosphotransferase system, glucitol/sorbitol-specific IIA component GO:0005737|GO:0008982|GO:0009401 KEGG: 00051+2.7.1.198|KEGG: 00710+2.7.1.19|MetaCyc: PWY-5723 ALX04_RS11420 3747c8d5fcd63ebb8e5df9417f974edf 125 Pfam PF03829 PTS system glucitol/sorbitol-specific IIA component 8 119 9.5E-35 T 28-03-2018 IPR004716 Phosphotransferase system, glucitol/sorbitol-specific IIA component GO:0005737|GO:0008982|GO:0009401 KEGG: 00051+2.7.1.198|KEGG: 00710+2.7.1.19|MetaCyc: PWY-5723 ALX04_RS11420 3747c8d5fcd63ebb8e5df9417f974edf 125 Gene3D G3DSA:2.40.33.40 7 122 1.1E-34 T 28-03-2018 IPR004716 Phosphotransferase system, glucitol/sorbitol-specific IIA component GO:0005737|GO:0008982|GO:0009401 KEGG: 00051+2.7.1.198|KEGG: 00710+2.7.1.19|MetaCyc: PWY-5723 ALX04_RS01025 ba0a869375be061299c7f5fbce84a257 390 SUPERFAMILY SSF56601 69 383 6.84E-53 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like ALX04_RS01025 ba0a869375be061299c7f5fbce84a257 390 Pfam PF00144 Beta-lactamase 84 372 1.1E-32 T 28-03-2018 IPR001466 Beta-lactamase-related ALX04_RS01025 ba0a869375be061299c7f5fbce84a257 390 Gene3D G3DSA:3.40.710.10 45 389 2.3E-46 T 28-03-2018 ALX04_RS10025 6f990a1bbb9862ab11d200471356330f 283 SUPERFAMILY SSF51735 4 248 3.56E-36 T 28-03-2018 IPR016040 NAD(P)-binding domain ALX04_RS10025 6f990a1bbb9862ab11d200471356330f 283 Gene3D G3DSA:3.40.50.720 1 185 1.3E-13 T 28-03-2018 ALX04_RS10025 6f990a1bbb9862ab11d200471356330f 283 Pfam PF13460 NAD(P)H-binding 8 146 1.5E-12 T 28-03-2018 IPR016040 NAD(P)-binding domain ALX04_RS08230 a9cb4102b0aee30582682827b73b1076 1005 Gene3D G3DSA:2.60.40.10 655 736 5.8E-10 T 28-03-2018 IPR013783 Immunoglobulin-like fold ALX04_RS08230 a9cb4102b0aee30582682827b73b1076 1005 Gene3D G3DSA:2.60.40.10 564 651 0.09 T 28-03-2018 IPR013783 Immunoglobulin-like fold ALX04_RS08230 a9cb4102b0aee30582682827b73b1076 1005 Pfam PF03382 Mycoplasma protein of unknown function, DUF285 296 385 1.1E-15 T 28-03-2018 IPR005046 Protein of unknown function DUF285 ALX04_RS08230 a9cb4102b0aee30582682827b73b1076 1005 Pfam PF03382 Mycoplasma protein of unknown function, DUF285 420 495 2.2E-4 T 28-03-2018 IPR005046 Protein of unknown function DUF285 ALX04_RS08230 a9cb4102b0aee30582682827b73b1076 1005 SUPERFAMILY SSF52058 322 501 5.44E-9 T 28-03-2018 IPR032675 Leucine-rich repeat domain, L domain-like ALX04_RS08230 a9cb4102b0aee30582682827b73b1076 1005 Gene3D G3DSA:2.60.40.10 741 816 1.1E-12 T 28-03-2018 IPR013783 Immunoglobulin-like fold ALX04_RS08230 a9cb4102b0aee30582682827b73b1076 1005 Pfam PF07523 Bacterial Ig-like domain (group 3) 671 729 3.2E-8 T 28-03-2018 IPR022038 Bacterial Ig-like domain ALX04_RS08230 a9cb4102b0aee30582682827b73b1076 1005 Pfam PF07523 Bacterial Ig-like domain (group 3) 744 813 1.2E-14 T 28-03-2018 IPR022038 Bacterial Ig-like domain ALX04_RS08230 a9cb4102b0aee30582682827b73b1076 1005 Pfam PF07523 Bacterial Ig-like domain (group 3) 571 644 4.8E-6 T 28-03-2018 IPR022038 Bacterial Ig-like domain ALX04_RS08230 a9cb4102b0aee30582682827b73b1076 1005 Gene3D G3DSA:3.80.10.10 77 522 7.4E-12 T 28-03-2018 IPR032675 Leucine-rich repeat domain, L domain-like ALX04_RS08230 a9cb4102b0aee30582682827b73b1076 1005 TIGRFAM TIGR02167 Liste_lipo_26: bacterial surface protein 26-residue repeat 383 409 5.7E-8 T 28-03-2018 IPR011889 Bacterial surface protein 26-residue repeat ALX04_RS08230 a9cb4102b0aee30582682827b73b1076 1005 TIGRFAM TIGR02167 Liste_lipo_26: bacterial surface protein 26-residue repeat 362 382 3.5E-4 T 28-03-2018 IPR011889 Bacterial surface protein 26-residue repeat ALX04_RS08230 a9cb4102b0aee30582682827b73b1076 1005 TIGRFAM TIGR02167 Liste_lipo_26: bacterial surface protein 26-residue repeat 328 352 2.6E-7 T 28-03-2018 IPR011889 Bacterial surface protein 26-residue repeat ALX04_RS08230 a9cb4102b0aee30582682827b73b1076 1005 TIGRFAM TIGR03715 KxYKxGKxW: KxYKxGKxW signal peptide 27 48 1.3E-8 T 28-03-2018 IPR022263 KxYKxGKxW signal peptide ALX04_RS14915 97b6f634463f092c736f4578b2ba4cba 195 SUPERFAMILY SSF46689 6 74 9.75E-11 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 ALX04_RS14915 97b6f634463f092c736f4578b2ba4cba 195 Gene3D G3DSA:1.10.10.60 2 47 3.9E-7 T 28-03-2018 ALX04_RS14915 97b6f634463f092c736f4578b2ba4cba 195 Gene3D G3DSA:1.10.10.60 48 131 4.1E-4 T 28-03-2018 ALX04_RS07635 46b879d18fd0eac816438f600ff3efe1 106 SMART SM00530 8 64 1.4E-13 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 ALX04_RS07635 46b879d18fd0eac816438f600ff3efe1 106 Pfam PF01381 Helix-turn-helix 9 64 2.0E-13 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 ALX04_RS07635 46b879d18fd0eac816438f600ff3efe1 106 Gene3D G3DSA:1.10.260.40 1 75 3.4E-18 T 28-03-2018 ALX04_RS07635 46b879d18fd0eac816438f600ff3efe1 106 SUPERFAMILY SSF47413 2 68 1.55E-16 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 ALX04_RS07155 1549b4431d9479b25c26303854bd735f 154 SMART SM00344 1 107 1.7E-24 T 28-03-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 ALX04_RS07155 1549b4431d9479b25c26303854bd735f 154 SUPERFAMILY SSF46785 1 61 2.97E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS07155 1549b4431d9479b25c26303854bd735f 154 Pfam PF01037 Lrp/AsnC ligand binding domain 67 134 2.9E-12 T 28-03-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain ALX04_RS07155 1549b4431d9479b25c26303854bd735f 154 Gene3D G3DSA:3.30.70.920 51 139 8.3E-18 T 28-03-2018 ALX04_RS07155 1549b4431d9479b25c26303854bd735f 154 Gene3D G3DSA:1.10.10.10 1 50 2.4E-14 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS07155 1549b4431d9479b25c26303854bd735f 154 SUPERFAMILY SSF54909 63 136 8.45E-17 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel ALX04_RS07155 1549b4431d9479b25c26303854bd735f 154 Pfam PF13412 Winged helix-turn-helix DNA-binding 1 48 6.4E-17 T 28-03-2018 ALX04_RS07155 1549b4431d9479b25c26303854bd735f 154 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 28 47 2.2E-9 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 ALX04_RS07155 1549b4431d9479b25c26303854bd735f 154 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 1 17 2.2E-9 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 ALX04_RS07155 1549b4431d9479b25c26303854bd735f 154 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 17 28 2.2E-9 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 ALX04_RS11260 9a925dd6c3c4e1c41b8a3973c3f0b983 352 Gene3D G3DSA:3.90.180.10 1 147 4.3E-40 T 28-03-2018 ALX04_RS11260 9a925dd6c3c4e1c41b8a3973c3f0b983 352 SUPERFAMILY SSF51735 137 309 4.18E-35 T 28-03-2018 IPR016040 NAD(P)-binding domain ALX04_RS11260 9a925dd6c3c4e1c41b8a3973c3f0b983 352 SMART SM00829 9 341 1.1E-6 T 28-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 ALX04_RS11260 9a925dd6c3c4e1c41b8a3973c3f0b983 352 SUPERFAMILY SSF50129 1 174 7.61E-50 T 28-03-2018 IPR011032 GroES-like ALX04_RS11260 9a925dd6c3c4e1c41b8a3973c3f0b983 352 Gene3D G3DSA:3.40.50.720 148 337 5.2E-26 T 28-03-2018 ALX04_RS11260 9a925dd6c3c4e1c41b8a3973c3f0b983 352 Pfam PF00107 Zinc-binding dehydrogenase 175 301 1.3E-26 T 28-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 ALX04_RS11260 9a925dd6c3c4e1c41b8a3973c3f0b983 352 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 27 131 2.5E-31 T 28-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 ALX04_RS11260 9a925dd6c3c4e1c41b8a3973c3f0b983 352 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 60 74 - T 28-03-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 ALX04_RS11800 cccad5c4cf5f7a9f9ee2e349c4bc0be2 141 Gene3D G3DSA:3.40.50.360 3 141 7.5E-15 T 28-03-2018 IPR029039 Flavoprotein-like domain ALX04_RS11800 cccad5c4cf5f7a9f9ee2e349c4bc0be2 141 SUPERFAMILY SSF52218 1 140 6.13E-15 T 28-03-2018 IPR029039 Flavoprotein-like domain ALX04_RS11800 cccad5c4cf5f7a9f9ee2e349c4bc0be2 141 Pfam PF12641 Flavodoxin domain 5 80 2.0E-7 T 28-03-2018 IPR008254 Flavodoxin/nitric oxide synthase GO:0010181 ALX04_RS08130 4222ee146ff9761cbce28a8726ffa7eb 223 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 27 40 6.5E-10 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 ALX04_RS08130 4222ee146ff9761cbce28a8726ffa7eb 223 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 48 71 6.5E-10 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 ALX04_RS08130 4222ee146ff9761cbce28a8726ffa7eb 223 Pfam PF00440 Bacterial regulatory proteins, tetR family 27 73 1.7E-16 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 ALX04_RS08130 4222ee146ff9761cbce28a8726ffa7eb 223 Gene3D G3DSA:1.10.10.60 2 48 5.7E-14 T 28-03-2018 ALX04_RS08130 4222ee146ff9761cbce28a8726ffa7eb 223 SUPERFAMILY SSF46689 23 87 2.98E-16 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 ALX04_RS08130 4222ee146ff9761cbce28a8726ffa7eb 223 Gene3D G3DSA:1.10.260.40 49 144 1.1E-13 T 28-03-2018 ALX04_RS15280 039360f43fe8d4644393c1eef0ade2f8 309 Hamap MF_00215 Pantothenate kinase [coaA]. 1 309 145.996 T 28-03-2018 IPR004566 Pantothenate kinase GO:0004594|GO:0005524|GO:0005737|GO:0015937 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 ALX04_RS15280 039360f43fe8d4644393c1eef0ade2f8 309 PIRSF PIRSF000545 1 309 2.5E-139 T 28-03-2018 IPR004566 Pantothenate kinase GO:0004594|GO:0005524|GO:0005737|GO:0015937 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 ALX04_RS15280 039360f43fe8d4644393c1eef0ade2f8 309 Pfam PF00485 Phosphoribulokinase / Uridine kinase family 87 235 4.3E-14 T 28-03-2018 IPR006083 Phosphoribulokinase/uridine kinase GO:0005524|GO:0008152|GO:0016301 Reactome: R-HSA-73614 ALX04_RS15280 039360f43fe8d4644393c1eef0ade2f8 309 Gene3D G3DSA:3.40.50.300 4 308 4.2E-49 T 28-03-2018 ALX04_RS15280 039360f43fe8d4644393c1eef0ade2f8 309 SUPERFAMILY SSF52540 1 307 1.84E-68 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase ALX04_RS15280 039360f43fe8d4644393c1eef0ade2f8 309 TIGRFAM TIGR00554 panK_bact: pantothenate kinase 7 308 3.4E-108 T 28-03-2018 IPR004566 Pantothenate kinase GO:0004594|GO:0005524|GO:0005737|GO:0015937 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 ALX04_RS11410 3dee4a0a6ffe15085bba04891059eac8 141 Pfam PF02082 Transcriptional regulator 2 80 9.4E-21 T 28-03-2018 IPR000944 Transcription regulator Rrf2-type ALX04_RS11410 3dee4a0a6ffe15085bba04891059eac8 141 SUPERFAMILY SSF46785 1 134 6.68E-30 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS11410 3dee4a0a6ffe15085bba04891059eac8 141 Gene3D G3DSA:1.10.10.10 1 141 5.5E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS14025 83903321f0eacf8a1dc4e8111485b7f6 174 Gene3D G3DSA:2.60.120.10 69 174 7.8E-10 T 28-03-2018 IPR014710 RmlC-like jelly roll fold ALX04_RS14025 83903321f0eacf8a1dc4e8111485b7f6 174 SUPERFAMILY SSF51182 72 172 7.9E-10 T 28-03-2018 IPR011051 RmlC-like cupin domain ALX04_RS14025 83903321f0eacf8a1dc4e8111485b7f6 174 Pfam PF07883 Cupin domain 107 168 2.0E-6 T 28-03-2018 IPR013096 Cupin 2, conserved barrel ALX04_RS03460 96dace06bba31631693da279d4a74070 352 Gene3D G3DSA:3.50.30.60 188 351 7.5E-39 T 28-03-2018 IPR027461 LD-carboxypeptidase A, C-terminal domain ALX04_RS03460 96dace06bba31631693da279d4a74070 352 PIRSF PIRSF028757 28 351 1.3E-62 T 28-03-2018 IPR003507 Peptidase family S66 ALX04_RS03460 96dace06bba31631693da279d4a74070 352 Pfam PF02016 LD-carboxypeptidase 33 340 6.3E-56 T 28-03-2018 IPR003507 Peptidase family S66 ALX04_RS03460 96dace06bba31631693da279d4a74070 352 SUPERFAMILY SSF52317 32 177 5.49E-30 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like ALX04_RS03460 96dace06bba31631693da279d4a74070 352 Gene3D G3DSA:3.40.50.10740 28 183 4.0E-31 T 28-03-2018 IPR027478 Murein tetrapeptide carboxypeptidase, N-terminal domain ALX04_RS03460 96dace06bba31631693da279d4a74070 352 SUPERFAMILY SSF141986 195 345 8.63E-35 T 28-03-2018 IPR027461 LD-carboxypeptidase A, C-terminal domain ALX04_RS14040 4f4b844f02c01a339517140ca602a007 368 Pfam PF03600 Citrate transporter 15 298 2.8E-18 T 28-03-2018 IPR004680 Citrate transporter-like domain GO:0016021|GO:0055085 Reactome: R-HSA-5662702 ALX04_RS00030 0494654dd7442e686061caaef1f37c2d 308 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 6.3E-5 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 ALX04_RS00030 0494654dd7442e686061caaef1f37c2d 308 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 6.3E-5 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 ALX04_RS00030 0494654dd7442e686061caaef1f37c2d 308 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 6.3E-5 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 ALX04_RS00030 0494654dd7442e686061caaef1f37c2d 308 Gene3D G3DSA:3.40.190.10 75 179 2.5E-8 T 28-03-2018 ALX04_RS00030 0494654dd7442e686061caaef1f37c2d 308 SUPERFAMILY SSF53850 93 304 6.05E-18 T 28-03-2018 ALX04_RS00030 0494654dd7442e686061caaef1f37c2d 308 Pfam PF03466 LysR substrate binding domain 93 297 2.3E-15 T 28-03-2018 IPR005119 LysR, substrate-binding ALX04_RS00030 0494654dd7442e686061caaef1f37c2d 308 Gene3D G3DSA:1.10.10.10 1 74 4.5E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS00030 0494654dd7442e686061caaef1f37c2d 308 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 62 3.6E-16 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 ALX04_RS00030 0494654dd7442e686061caaef1f37c2d 308 Gene3D G3DSA:3.40.190.10 180 269 9.0E-5 T 28-03-2018 ALX04_RS00030 0494654dd7442e686061caaef1f37c2d 308 SUPERFAMILY SSF46785 2 110 1.63E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS09590 c4d08cb1209d8e82076332ed73c77088 242 Pfam PF00106 short chain dehydrogenase 5 191 4.9E-53 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR ALX04_RS09590 c4d08cb1209d8e82076332ed73c77088 242 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 168 185 1.0E-26 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR ALX04_RS09590 c4d08cb1209d8e82076332ed73c77088 242 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 74 85 1.0E-26 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR ALX04_RS09590 c4d08cb1209d8e82076332ed73c77088 242 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 121 137 1.0E-26 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR ALX04_RS09590 c4d08cb1209d8e82076332ed73c77088 242 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 147 166 1.0E-26 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR ALX04_RS09590 c4d08cb1209d8e82076332ed73c77088 242 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 4 21 1.0E-26 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR ALX04_RS09590 c4d08cb1209d8e82076332ed73c77088 242 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 3 182 0.006 T 28-03-2018 ALX04_RS09590 c4d08cb1209d8e82076332ed73c77088 242 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 147 166 5.2E-10 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR ALX04_RS09590 c4d08cb1209d8e82076332ed73c77088 242 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 127 135 5.2E-10 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR ALX04_RS09590 c4d08cb1209d8e82076332ed73c77088 242 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 74 85 5.2E-10 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR ALX04_RS09590 c4d08cb1209d8e82076332ed73c77088 242 Gene3D G3DSA:3.40.50.720 42 233 5.3E-44 T 28-03-2018 ALX04_RS09590 c4d08cb1209d8e82076332ed73c77088 242 Gene3D G3DSA:3.40.50.720 2 41 1.3E-5 T 28-03-2018 ALX04_RS09590 c4d08cb1209d8e82076332ed73c77088 242 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 134 162 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 ALX04_RS09590 c4d08cb1209d8e82076332ed73c77088 242 SUPERFAMILY SSF51735 4 226 2.91E-58 T 28-03-2018 IPR016040 NAD(P)-binding domain ALX04_RS15115 ea18be68f2502aae735fe179b20dbae9 208 Gene3D G3DSA:3.40.50.1000 1 28 0.38 T 28-03-2018 IPR023214 HAD-like domain ALX04_RS15115 ea18be68f2502aae735fe179b20dbae9 208 Pfam PF13419 Haloacid dehalogenase-like hydrolase 7 177 4.1E-33 T 28-03-2018 IPR023214 HAD-like domain ALX04_RS15115 ea18be68f2502aae735fe179b20dbae9 208 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 6 173 2.0E-9 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 ALX04_RS15115 ea18be68f2502aae735fe179b20dbae9 208 Gene3D G3DSA:3.40.50.1000 72 208 6.2E-20 T 28-03-2018 IPR023214 HAD-like domain ALX04_RS15115 ea18be68f2502aae735fe179b20dbae9 208 SUPERFAMILY SSF56784 1 206 2.63E-43 T 28-03-2018 IPR023214 HAD-like domain ALX04_RS15115 ea18be68f2502aae735fe179b20dbae9 208 Gene3D G3DSA:1.10.150.240 29 71 9.4E-45 T 28-03-2018 IPR023198 Phosphoglycolate phosphatase, domain 2 ALX04_RS04630 1c03cc2fe937896c4c310cea985b0204 259 ProSitePatterns PS01066 Undecaprenyl pyrophosphate synthase family signature. 199 216 - T 28-03-2018 IPR018520 Di-trans-poly-cis-decaprenylcistransferase-like, conserved site GO:0016765 Reactome: R-HSA-446199 ALX04_RS04630 1c03cc2fe937896c4c310cea985b0204 259 TIGRFAM TIGR00055 uppS: di-trans,poly-cis-decaprenylcistransferase 23 253 8.4E-83 T 28-03-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 ALX04_RS04630 1c03cc2fe937896c4c310cea985b0204 259 Hamap MF_01139 Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) [uppS]. 23 254 38.229 T 28-03-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 ALX04_RS04630 1c03cc2fe937896c4c310cea985b0204 259 SUPERFAMILY SSF64005 18 248 3.01E-85 T 28-03-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 ALX04_RS04630 1c03cc2fe937896c4c310cea985b0204 259 Gene3D G3DSA:3.40.1180.10 10 257 2.5E-89 T 28-03-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 ALX04_RS04630 1c03cc2fe937896c4c310cea985b0204 259 Pfam PF01255 Putative undecaprenyl diphosphate synthase 30 253 3.8E-79 T 28-03-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 ALX04_RS01885 7674a677dee36f00d6889d28042783cf 318 Pfam PF02272 DHHA1 domain 250 307 6.1E-8 T 28-03-2018 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 ALX04_RS01885 7674a677dee36f00d6889d28042783cf 318 SUPERFAMILY SSF64182 17 303 3.66E-67 T 28-03-2018 ALX04_RS01885 7674a677dee36f00d6889d28042783cf 318 Gene3D G3DSA:3.90.1640.10 3 194 2.3E-38 T 28-03-2018 ALX04_RS01885 7674a677dee36f00d6889d28042783cf 318 Pfam PF01368 DHH family 19 154 6.3E-13 T 28-03-2018 IPR001667 DDH domain KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 ALX04_RS07215 184f876f42274eae1a84ee4dfe2b1ff3 426 Pfam PF00742 Homoserine dehydrogenase 139 316 7.8E-54 T 28-03-2018 IPR001342 Homoserine dehydrogenase, catalytic GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 ALX04_RS07215 184f876f42274eae1a84ee4dfe2b1ff3 426 ProSitePatterns PS01042 Homoserine dehydrogenase signature. 184 206 - T 28-03-2018 IPR019811 Homoserine dehydrogenase, conserved site GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 ALX04_RS07215 184f876f42274eae1a84ee4dfe2b1ff3 426 SUPERFAMILY SSF51735 2 160 1.52E-29 T 28-03-2018 IPR016040 NAD(P)-binding domain ALX04_RS07215 184f876f42274eae1a84ee4dfe2b1ff3 426 Gene3D G3DSA:3.40.50.720 1 159 1.1E-26 T 28-03-2018 ALX04_RS07215 184f876f42274eae1a84ee4dfe2b1ff3 426 SUPERFAMILY SSF55347 139 303 5.82E-45 T 28-03-2018 ALX04_RS07215 184f876f42274eae1a84ee4dfe2b1ff3 426 Gene3D G3DSA:3.30.360.10 160 299 1.0E-44 T 28-03-2018 ALX04_RS07215 184f876f42274eae1a84ee4dfe2b1ff3 426 Pfam PF03447 Homoserine dehydrogenase, NAD binding domain 11 131 2.3E-18 T 28-03-2018 IPR005106 Aspartate/homoserine dehydrogenase, NAD-binding GO:0016491|GO:0050661|GO:0055114 ALX04_RS07215 184f876f42274eae1a84ee4dfe2b1ff3 426 PIRSF PIRSF000098 2 377 4.5E-115 T 28-03-2018 IPR016204 Homoserine dehydrogenase GO:0004412|GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 ALX04_RS05245 30c0a6d5d0eda7f1fb9b75e83c41e7a4 353 Pfam PF06144 DNA polymerase III, delta subunit 22 196 1.2E-41 T 28-03-2018 IPR010372 DNA polymerase III delta, N-terminal GO:0003677|GO:0003887|GO:0006260|GO:0009360 ALX04_RS05245 30c0a6d5d0eda7f1fb9b75e83c41e7a4 353 Gene3D G3DSA:1.10.8.60 150 228 1.6E-16 T 28-03-2018 ALX04_RS05245 30c0a6d5d0eda7f1fb9b75e83c41e7a4 353 SUPERFAMILY SSF52540 8 215 4.25E-18 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase ALX04_RS05245 30c0a6d5d0eda7f1fb9b75e83c41e7a4 353 Gene3D G3DSA:3.40.50.300 1 147 5.4E-24 T 28-03-2018 ALX04_RS05245 30c0a6d5d0eda7f1fb9b75e83c41e7a4 353 SUPERFAMILY SSF48019 220 338 1.62E-23 T 28-03-2018 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 ALX04_RS05245 30c0a6d5d0eda7f1fb9b75e83c41e7a4 353 TIGRFAM TIGR01128 holA: DNA polymerase III, delta subunit 18 339 5.5E-92 T 28-03-2018 IPR005790 DNA polymerase III, delta subunit GO:0003677|GO:0006260 ALX04_RS05245 30c0a6d5d0eda7f1fb9b75e83c41e7a4 353 Gene3D G3DSA:1.20.272.10 229 349 6.1E-30 T 28-03-2018 ALX04_RS02685 a2b6544a117cd84addefb5b4655745ac 102 Pfam PF00829 Ribosomal prokaryotic L21 protein 2 100 1.6E-36 T 28-03-2018 IPR028909 Ribosomal protein L21-like GO:0005840 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 ALX04_RS02685 a2b6544a117cd84addefb5b4655745ac 102 SUPERFAMILY SSF141091 1 101 9.29E-36 T 28-03-2018 IPR028909 Ribosomal protein L21-like GO:0005840 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 ALX04_RS02685 a2b6544a117cd84addefb5b4655745ac 102 ProSitePatterns PS01169 Ribosomal protein L21 signature. 71 93 - T 28-03-2018 IPR018258 Ribosomal protein L21, conserved site GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 ALX04_RS02685 a2b6544a117cd84addefb5b4655745ac 102 Hamap MF_01363 50S ribosomal protein L21 [rplU]. 1 102 24.912 T 28-03-2018 IPR001787 Ribosomal protein L21 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 ALX04_RS02685 a2b6544a117cd84addefb5b4655745ac 102 TIGRFAM TIGR00061 L21: ribosomal protein bL21 2 100 1.9E-37 T 28-03-2018 IPR001787 Ribosomal protein L21 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 ALX04_RS02170 76cc4360f02f9534c54a2a38c60bea46 1092 Gene3D G3DSA:2.60.40.1310 773 913 6.3E-7 T 28-03-2018 ALX04_RS02170 76cc4360f02f9534c54a2a38c60bea46 1092 Pfam PF13731 WxL domain surface cell wall-binding 887 1088 1.4E-32 T 28-03-2018 IPR027994 WxL domain ALX04_RS14920 7ecfab489677f477b1348d3306b815fd 349 SUPERFAMILY SSF74650 13 344 4.14E-83 T 28-03-2018 IPR011013 Galactose mutarotase-like domain GO:0003824|GO:0005975|GO:0030246 ALX04_RS14920 7ecfab489677f477b1348d3306b815fd 349 Pfam PF01263 Aldose 1-epimerase 24 341 6.2E-67 T 28-03-2018 IPR008183 Aldose 1-/Glucose-6-phosphate 1-epimerase GO:0005975|GO:0016853 ALX04_RS14920 7ecfab489677f477b1348d3306b815fd 349 Gene3D G3DSA:2.70.98.10 11 347 1.6E-79 T 28-03-2018 IPR014718 Glycoside hydrolase-type carbohydrate-binding GO:0030246 ALX04_RS14920 7ecfab489677f477b1348d3306b815fd 349 PIRSF PIRSF005096 8 346 6.1E-88 T 28-03-2018 IPR015443 Aldose 1-epimerase GO:0016853|GO:0019318 KEGG: 00010+5.1.3.3|KEGG: 00052+5.1.3.3|MetaCyc: PWY-6317 ALX04_RS12270 a1b474cf51aaef8d3aaee1f1eb250fe7 172 Gene3D G3DSA:1.10.10.60 2 44 2.6E-8 T 28-03-2018 ALX04_RS12270 a1b474cf51aaef8d3aaee1f1eb250fe7 172 Gene3D G3DSA:1.10.10.60 45 142 2.3E-4 T 28-03-2018 ALX04_RS12270 a1b474cf51aaef8d3aaee1f1eb250fe7 172 TIGRFAM TIGR02366 DHAK_reg: probable dihydroxyacetone kinase regulator 2 168 2.1E-67 T 28-03-2018 IPR012738 Transcription regulator DhaS ALX04_RS12270 a1b474cf51aaef8d3aaee1f1eb250fe7 172 Pfam PF00440 Bacterial regulatory proteins, tetR family 20 52 3.1E-6 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 ALX04_RS12270 a1b474cf51aaef8d3aaee1f1eb250fe7 172 SUPERFAMILY SSF46689 4 65 6.16E-13 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 ALX04_RS04550 3a7e2a2d766061e105c7ea532a05a2c9 173 Gene3D G3DSA:3.40.50.300 2 172 1.7E-24 T 28-03-2018 ALX04_RS04550 3a7e2a2d766061e105c7ea532a05a2c9 173 Hamap MF_00109 Shikimate kinase [aroK]. 1 165 21.87 T 28-03-2018 IPR000623 Shikimate kinase/Threonine synthase-like 1 KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 ALX04_RS04550 3a7e2a2d766061e105c7ea532a05a2c9 173 Pfam PF01202 Shikimate kinase 9 164 2.8E-38 T 28-03-2018 IPR031322 Shikimate kinase/gluconokinase KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 ALX04_RS04550 3a7e2a2d766061e105c7ea532a05a2c9 173 PRINTS PR01100 Shikimate kinase family signature 3 18 1.3E-15 T 28-03-2018 ALX04_RS04550 3a7e2a2d766061e105c7ea532a05a2c9 173 PRINTS PR01100 Shikimate kinase family signature 27 40 1.3E-15 T 28-03-2018 ALX04_RS04550 3a7e2a2d766061e105c7ea532a05a2c9 173 PRINTS PR01100 Shikimate kinase family signature 72 81 1.3E-15 T 28-03-2018 ALX04_RS04550 3a7e2a2d766061e105c7ea532a05a2c9 173 PRINTS PR01100 Shikimate kinase family signature 55 63 1.3E-15 T 28-03-2018 ALX04_RS04550 3a7e2a2d766061e105c7ea532a05a2c9 173 PRINTS PR01100 Shikimate kinase family signature 94 111 1.3E-15 T 28-03-2018 ALX04_RS04550 3a7e2a2d766061e105c7ea532a05a2c9 173 SUPERFAMILY SSF52540 3 165 2.47E-23 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase ALX04_RS00405 5cacc9233627a3844782da2862459392 115 TIGRFAM TIGR01044 rplV_bact: ribosomal protein uL22 10 112 7.0E-47 T 28-03-2018 IPR005727 Ribosomal protein L22, bacterial/chloroplast-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 ALX04_RS00405 5cacc9233627a3844782da2862459392 115 Hamap MF_01331_B 50S ribosomal protein L22 [rplV]. 6 115 29.857 T 28-03-2018 IPR005727 Ribosomal protein L22, bacterial/chloroplast-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 ALX04_RS00405 5cacc9233627a3844782da2862459392 115 Gene3D G3DSA:3.90.470.10 2 115 1.6E-43 T 28-03-2018 ALX04_RS00405 5cacc9233627a3844782da2862459392 115 ProSitePatterns PS00464 Ribosomal protein L22 signature. 88 112 - T 28-03-2018 IPR018260 Ribosomal protein L22/L17, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 ALX04_RS00405 5cacc9233627a3844782da2862459392 115 Pfam PF00237 Ribosomal protein L22p/L17e 10 112 1.9E-36 T 28-03-2018 IPR001063 Ribosomal protein L22/L17 GO:0003735|GO:0005840|GO:0006412 ALX04_RS00405 5cacc9233627a3844782da2862459392 115 SUPERFAMILY SSF54843 6 115 8.63E-43 T 28-03-2018 IPR001063 Ribosomal protein L22/L17 GO:0003735|GO:0005840|GO:0006412 ALX04_RS13065 8854c491c80ececa5ddbf0cbfc340de9 391 SUPERFAMILY SSF53383 6 386 5.64E-102 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase ALX04_RS13065 8854c491c80ececa5ddbf0cbfc340de9 391 Gene3D G3DSA:3.90.1150.10 9 255 8.0E-37 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 ALX04_RS13065 8854c491c80ececa5ddbf0cbfc340de9 391 Gene3D G3DSA:3.90.1150.10 256 388 6.8E-35 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 ALX04_RS13065 8854c491c80ececa5ddbf0cbfc340de9 391 Pfam PF00155 Aminotransferase class I and II 33 383 5.9E-66 T 28-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 ALX04_RS10065 3734b59b7268bd8eec6ae4ad9e684510 152 Pfam PF13411 MerR HTH family regulatory protein 22 84 2.3E-13 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 ALX04_RS10065 3734b59b7268bd8eec6ae4ad9e684510 152 SMART SM00422 20 90 0.0019 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 ALX04_RS10065 3734b59b7268bd8eec6ae4ad9e684510 152 SUPERFAMILY SSF46955 21 98 2.88E-14 T 28-03-2018 IPR009061 Putative DNA-binding domain ALX04_RS10065 3734b59b7268bd8eec6ae4ad9e684510 152 Gene3D G3DSA:1.10.1660.10 14 129 1.2E-15 T 28-03-2018 ALX04_RS14410 5078858639444e86d59adb59b8a4f541 261 Pfam PF01643 Acyl-ACP thioesterase 10 254 6.1E-66 T 28-03-2018 IPR002864 Acyl-ACP thioesterase GO:0006633|GO:0016790 ALX04_RS14410 5078858639444e86d59adb59b8a4f541 261 Gene3D G3DSA:3.10.129.10 152 254 1.5E-19 T 28-03-2018 ALX04_RS14410 5078858639444e86d59adb59b8a4f541 261 SUPERFAMILY SSF54637 10 148 1.82E-41 T 28-03-2018 IPR029069 HotDog domain ALX04_RS14410 5078858639444e86d59adb59b8a4f541 261 Gene3D G3DSA:3.10.129.10 5 141 6.5E-17 T 28-03-2018 ALX04_RS14410 5078858639444e86d59adb59b8a4f541 261 SUPERFAMILY SSF54637 157 254 1.1E-23 T 28-03-2018 IPR029069 HotDog domain ALX04_RS14490 c03ff914b537168cf49b4e2c5453100c 94 PRINTS PR00297 10kDa chaperonin signature 59 71 6.9E-27 T 28-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 ALX04_RS14490 c03ff914b537168cf49b4e2c5453100c 94 PRINTS PR00297 10kDa chaperonin signature 80 93 6.9E-27 T 28-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 ALX04_RS14490 c03ff914b537168cf49b4e2c5453100c 94 PRINTS PR00297 10kDa chaperonin signature 24 45 6.9E-27 T 28-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 ALX04_RS14490 c03ff914b537168cf49b4e2c5453100c 94 PRINTS PR00297 10kDa chaperonin signature 2 17 6.9E-27 T 28-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 ALX04_RS14490 c03ff914b537168cf49b4e2c5453100c 94 Gene3D G3DSA:2.30.33.40 1 94 9.9E-34 T 28-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 ALX04_RS14490 c03ff914b537168cf49b4e2c5453100c 94 Hamap MF_00580 10 kDa chaperonin [groS]. 1 94 24.224 T 28-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 ALX04_RS14490 c03ff914b537168cf49b4e2c5453100c 94 Pfam PF00166 Chaperonin 10 Kd subunit 2 92 1.2E-33 T 28-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 ALX04_RS14490 c03ff914b537168cf49b4e2c5453100c 94 SUPERFAMILY SSF50129 2 92 4.71E-31 T 28-03-2018 IPR011032 GroES-like ALX04_RS14490 c03ff914b537168cf49b4e2c5453100c 94 SMART SM00883 1 93 4.3E-48 T 28-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 ALX04_RS14490 c03ff914b537168cf49b4e2c5453100c 94 ProSitePatterns PS00681 Chaperonins cpn10 signature. 2 26 - T 28-03-2018 IPR018369 Chaperonin GroES, conserved site GO:0005524|GO:0006457 ALX04_RS00860 eab0db9025f661563e5ea9e7171ce24d 755 Pfam PF00580 UvrD/REP helicase N-terminal domain 10 273 4.2E-83 T 28-03-2018 IPR034739 UvrD/AddA helicase, N-terminal GO:0005524 ALX04_RS00860 eab0db9025f661563e5ea9e7171ce24d 755 TIGRFAM TIGR01073 pcrA: ATP-dependent DNA helicase PcrA 6 751 0.0 T 28-03-2018 IPR005751 ATP-dependent DNA helicase PcrA GO:0004003|GO:0005737|GO:0006268 ALX04_RS00860 eab0db9025f661563e5ea9e7171ce24d 755 Gene3D G3DSA:3.40.50.300 283 386 2.1E-28 T 28-03-2018 ALX04_RS00860 eab0db9025f661563e5ea9e7171ce24d 755 Pfam PF13361 UvrD-like helicase C-terminal domain 278 621 5.0E-74 T 28-03-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 ALX04_RS00860 eab0db9025f661563e5ea9e7171ce24d 755 Gene3D G3DSA:3.40.50.300 2 144 3.3E-29 T 28-03-2018 ALX04_RS00860 eab0db9025f661563e5ea9e7171ce24d 755 Gene3D G3DSA:3.40.50.300 145 282 1.5E-34 T 28-03-2018 ALX04_RS00860 eab0db9025f661563e5ea9e7171ce24d 755 Gene3D G3DSA:3.40.50.300 387 676 4.2E-52 T 28-03-2018 ALX04_RS00860 eab0db9025f661563e5ea9e7171ce24d 755 SUPERFAMILY SSF52540 4 649 9.07E-183 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase ALX04_RS03710 585f973ee9657972a98414e5aa32c678 435 Gene3D G3DSA:3.90.550.10 29 311 3.2E-30 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases ALX04_RS03710 585f973ee9657972a98414e5aa32c678 435 Pfam PF13632 Glycosyl transferase family group 2 141 341 1.3E-16 T 28-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 ALX04_RS03710 585f973ee9657972a98414e5aa32c678 435 SUPERFAMILY SSF53448 46 296 4.88E-31 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases ALX04_RS09725 e3b8699bdaa18e67b1dff5bd683c08af 296 Gene3D G3DSA:1.10.10.60 6 33 0.0021 T 28-03-2018 ALX04_RS09725 e3b8699bdaa18e67b1dff5bd683c08af 296 SUPERFAMILY SSF53098 124 284 3.67E-36 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 ALX04_RS09725 e3b8699bdaa18e67b1dff5bd683c08af 296 Pfam PF00665 Integrase core domain 129 243 1.3E-29 T 28-03-2018 IPR001584 Integrase, catalytic core GO:0015074 ALX04_RS09725 e3b8699bdaa18e67b1dff5bd683c08af 296 Pfam PF13276 HTH-like domain 41 102 1.0E-10 T 28-03-2018 IPR025948 HTH-like domain ALX04_RS09725 e3b8699bdaa18e67b1dff5bd683c08af 296 Gene3D G3DSA:3.30.420.10 122 296 3.4E-38 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 ALX04_RS01895 6d5f10846ec28109289a273b9879002d 591 Pfam PF03600 Citrate transporter 16 521 9.9E-35 T 28-03-2018 IPR004680 Citrate transporter-like domain GO:0016021|GO:0055085 Reactome: R-HSA-5662702 ALX04_RS01895 6d5f10846ec28109289a273b9879002d 591 Gene3D G3DSA:3.30.70.1450 215 297 5.2E-10 T 28-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 ALX04_RS01895 6d5f10846ec28109289a273b9879002d 591 Pfam PF02080 TrkA-C domain 231 288 1.2E-6 T 28-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 ALX04_RS01895 6d5f10846ec28109289a273b9879002d 591 Pfam PF02080 TrkA-C domain 310 370 2.5E-7 T 28-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 ALX04_RS01895 6d5f10846ec28109289a273b9879002d 591 Gene3D G3DSA:3.30.70.1450 298 383 9.7E-13 T 28-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 ALX04_RS01895 6d5f10846ec28109289a273b9879002d 591 SUPERFAMILY SSF116726 300 370 4.05E-14 T 28-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 ALX04_RS01895 6d5f10846ec28109289a273b9879002d 591 SUPERFAMILY SSF116726 206 293 1.57E-14 T 28-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 ALX04_RS01805 864023badeb61af251a454557138afc9 159 Gene3D G3DSA:1.10.10.10 10 147 1.7E-23 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS01805 864023badeb61af251a454557138afc9 159 Pfam PF01047 MarR family 39 97 2.5E-16 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 ALX04_RS01805 864023badeb61af251a454557138afc9 159 SMART SM00347 32 130 2.8E-20 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 ALX04_RS01805 864023badeb61af251a454557138afc9 159 SUPERFAMILY SSF46785 11 139 8.24E-31 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS14625 c12ae1d550ea21a660a2ea6bf8b95722 470 Gene3D G3DSA:3.50.50.60 122 252 4.3E-23 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ALX04_RS14625 c12ae1d550ea21a660a2ea6bf8b95722 470 Gene3D G3DSA:3.50.50.60 253 329 3.2E-9 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ALX04_RS14625 c12ae1d550ea21a660a2ea6bf8b95722 470 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 235 249 7.6E-13 T 28-03-2018 ALX04_RS14625 c12ae1d550ea21a660a2ea6bf8b95722 470 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 2 24 7.6E-13 T 28-03-2018 ALX04_RS14625 c12ae1d550ea21a660a2ea6bf8b95722 470 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 275 282 7.6E-13 T 28-03-2018 ALX04_RS14625 c12ae1d550ea21a660a2ea6bf8b95722 470 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 149 174 7.6E-13 T 28-03-2018 ALX04_RS14625 c12ae1d550ea21a660a2ea6bf8b95722 470 Gene3D G3DSA:3.50.50.60 1 121 2.1E-12 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ALX04_RS14625 c12ae1d550ea21a660a2ea6bf8b95722 470 SUPERFAMILY SSF55424 321 444 2.06E-32 T 28-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 ALX04_RS14625 c12ae1d550ea21a660a2ea6bf8b95722 470 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 234 250 5.0E-21 T 28-03-2018 ALX04_RS14625 c12ae1d550ea21a660a2ea6bf8b95722 470 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 104 122 5.0E-21 T 28-03-2018 ALX04_RS14625 c12ae1d550ea21a660a2ea6bf8b95722 470 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 260 282 5.0E-21 T 28-03-2018 ALX04_RS14625 c12ae1d550ea21a660a2ea6bf8b95722 470 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 149 167 5.0E-21 T 28-03-2018 ALX04_RS14625 c12ae1d550ea21a660a2ea6bf8b95722 470 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 3 22 5.0E-21 T 28-03-2018 ALX04_RS14625 c12ae1d550ea21a660a2ea6bf8b95722 470 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 2 305 3.5E-57 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ALX04_RS14625 c12ae1d550ea21a660a2ea6bf8b95722 470 Gene3D G3DSA:3.30.390.30 330 453 3.0E-20 T 28-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 ALX04_RS14625 c12ae1d550ea21a660a2ea6bf8b95722 470 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 331 431 2.2E-10 T 28-03-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 ALX04_RS14625 c12ae1d550ea21a660a2ea6bf8b95722 470 SUPERFAMILY SSF51905 1 314 3.24E-41 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ALX04_RS01295 0dc65630eacb8c8c776bb199a57b1590 308 PIRSF PIRSF000102 1 308 1.4E-83 T 28-03-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 ALX04_RS01295 0dc65630eacb8c8c776bb199a57b1590 308 Pfam PF00056 lactate/malate dehydrogenase, NAD binding domain 4 145 9.5E-23 T 28-03-2018 IPR001236 Lactate/malate dehydrogenase, N-terminal GO:0016491|GO:0055114 ALX04_RS01295 0dc65630eacb8c8c776bb199a57b1590 308 SUPERFAMILY SSF56327 146 302 1.35E-41 T 28-03-2018 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 ALX04_RS01295 0dc65630eacb8c8c776bb199a57b1590 308 Gene3D G3DSA:3.90.110.10 149 307 1.3E-34 T 28-03-2018 ALX04_RS01295 0dc65630eacb8c8c776bb199a57b1590 308 Gene3D G3DSA:3.40.50.720 4 147 2.7E-23 T 28-03-2018 ALX04_RS01295 0dc65630eacb8c8c776bb199a57b1590 308 ProSitePatterns PS00064 L-lactate dehydrogenase active site. 175 181 - T 28-03-2018 IPR018177 L-lactate dehydrogenase, active site GO:0004459|GO:0055114 KEGG: 00010+1.1.1.27|KEGG: 00270+1.1.1.27|KEGG: 00620+1.1.1.27|KEGG: 00640+1.1.1.27|MetaCyc: PWY-5481|MetaCyc: PWY-6901|Reactome: R-HSA-70268 ALX04_RS01295 0dc65630eacb8c8c776bb199a57b1590 308 SUPERFAMILY SSF51735 2 147 4.96E-41 T 28-03-2018 IPR016040 NAD(P)-binding domain ALX04_RS01295 0dc65630eacb8c8c776bb199a57b1590 308 Pfam PF02866 lactate/malate dehydrogenase, alpha/beta C-terminal domain 148 303 1.2E-12 T 28-03-2018 IPR022383 Lactate/malate dehydrogenase, C-terminal GO:0016616|GO:0055114 ALX04_RS01295 0dc65630eacb8c8c776bb199a57b1590 308 PRINTS PR00086 L-lactate dehydrogenase signature 4 28 5.0E-31 T 28-03-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 ALX04_RS01295 0dc65630eacb8c8c776bb199a57b1590 308 PRINTS PR00086 L-lactate dehydrogenase signature 173 186 5.0E-31 T 28-03-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 ALX04_RS01295 0dc65630eacb8c8c776bb199a57b1590 308 PRINTS PR00086 L-lactate dehydrogenase signature 119 139 5.0E-31 T 28-03-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 ALX04_RS01295 0dc65630eacb8c8c776bb199a57b1590 308 PRINTS PR00086 L-lactate dehydrogenase signature 29 53 5.0E-31 T 28-03-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 ALX04_RS01295 0dc65630eacb8c8c776bb199a57b1590 308 PRINTS PR00086 L-lactate dehydrogenase signature 143 161 5.0E-31 T 28-03-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 ALX04_RS10120 b7111a474c2d0090aaeddea3bb799416 284 Gene3D G3DSA:3.60.21.10 2 268 7.4E-40 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like ALX04_RS10120 b7111a474c2d0090aaeddea3bb799416 284 SUPERFAMILY SSF56300 3 253 1.83E-42 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like ALX04_RS10120 b7111a474c2d0090aaeddea3bb799416 284 Pfam PF00149 Calcineurin-like phosphoesterase 5 200 3.8E-17 T 28-03-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 ALX04_RS03365 c6486ec4fc42edd4bcdaa7b85dcdac5c 285 SUPERFAMILY SSF53850 36 277 9.32E-67 T 28-03-2018 ALX04_RS03365 c6486ec4fc42edd4bcdaa7b85dcdac5c 285 Gene3D G3DSA:3.40.190.10 33 135 1.1E-13 T 28-03-2018 ALX04_RS03365 c6486ec4fc42edd4bcdaa7b85dcdac5c 285 Gene3D G3DSA:3.40.190.10 136 278 5.9E-36 T 28-03-2018 ALX04_RS03365 c6486ec4fc42edd4bcdaa7b85dcdac5c 285 Pfam PF03180 NLPA lipoprotein 37 275 4.5E-68 T 28-03-2018 IPR004872 Lipoprotein NlpA family ALX04_RS00655 eae1fbc97034d5660d926b355dcc969d 313 PRINTS PR00691 Adhesin B signature 62 80 9.3E-76 T 28-03-2018 IPR006129 Adhesin B GO:0007155 ALX04_RS00655 eae1fbc97034d5660d926b355dcc969d 313 PRINTS PR00691 Adhesin B signature 268 286 9.3E-76 T 28-03-2018 IPR006129 Adhesin B GO:0007155 ALX04_RS00655 eae1fbc97034d5660d926b355dcc969d 313 PRINTS PR00691 Adhesin B signature 223 241 9.3E-76 T 28-03-2018 IPR006129 Adhesin B GO:0007155 ALX04_RS00655 eae1fbc97034d5660d926b355dcc969d 313 PRINTS PR00691 Adhesin B signature 81 100 9.3E-76 T 28-03-2018 IPR006129 Adhesin B GO:0007155 ALX04_RS00655 eae1fbc97034d5660d926b355dcc969d 313 PRINTS PR00691 Adhesin B signature 139 158 9.3E-76 T 28-03-2018 IPR006129 Adhesin B GO:0007155 ALX04_RS00655 eae1fbc97034d5660d926b355dcc969d 313 PRINTS PR00691 Adhesin B signature 37 58 9.3E-76 T 28-03-2018 IPR006129 Adhesin B GO:0007155 ALX04_RS00655 eae1fbc97034d5660d926b355dcc969d 313 PRINTS PR00691 Adhesin B signature 197 214 9.3E-76 T 28-03-2018 IPR006129 Adhesin B GO:0007155 ALX04_RS00655 eae1fbc97034d5660d926b355dcc969d 313 PRINTS PR00691 Adhesin B signature 246 263 9.3E-76 T 28-03-2018 IPR006129 Adhesin B GO:0007155 ALX04_RS00655 eae1fbc97034d5660d926b355dcc969d 313 PRINTS PR00691 Adhesin B signature 289 307 9.3E-76 T 28-03-2018 IPR006129 Adhesin B GO:0007155 ALX04_RS00655 eae1fbc97034d5660d926b355dcc969d 313 Gene3D G3DSA:3.40.50.1980 190 311 1.5E-29 T 28-03-2018 ALX04_RS00655 eae1fbc97034d5660d926b355dcc969d 313 PRINTS PR00690 Adhesin family signature 81 98 3.7E-49 T 28-03-2018 IPR006128 Adhesion lipoprotein GO:0007155 ALX04_RS00655 eae1fbc97034d5660d926b355dcc969d 313 PRINTS PR00690 Adhesin family signature 250 268 3.7E-49 T 28-03-2018 IPR006128 Adhesion lipoprotein GO:0007155 ALX04_RS00655 eae1fbc97034d5660d926b355dcc969d 313 PRINTS PR00690 Adhesin family signature 197 218 3.7E-49 T 28-03-2018 IPR006128 Adhesion lipoprotein GO:0007155 ALX04_RS00655 eae1fbc97034d5660d926b355dcc969d 313 PRINTS PR00690 Adhesin family signature 68 81 3.7E-49 T 28-03-2018 IPR006128 Adhesion lipoprotein GO:0007155 ALX04_RS00655 eae1fbc97034d5660d926b355dcc969d 313 PRINTS PR00690 Adhesin family signature 37 55 3.7E-49 T 28-03-2018 IPR006128 Adhesion lipoprotein GO:0007155 ALX04_RS00655 eae1fbc97034d5660d926b355dcc969d 313 PRINTS PR00690 Adhesin family signature 276 295 3.7E-49 T 28-03-2018 IPR006128 Adhesion lipoprotein GO:0007155 ALX04_RS00655 eae1fbc97034d5660d926b355dcc969d 313 SUPERFAMILY SSF53807 32 310 1.14E-81 T 28-03-2018 ALX04_RS00655 eae1fbc97034d5660d926b355dcc969d 313 Pfam PF01297 Zinc-uptake complex component A periplasmic 40 307 1.5E-70 T 28-03-2018 IPR006127 Periplasmic solute binding protein, ZnuA-like GO:0030001|GO:0046872 ALX04_RS00655 eae1fbc97034d5660d926b355dcc969d 313 Gene3D G3DSA:3.40.50.1980 26 189 4.1E-43 T 28-03-2018 ALX04_RS02585 0756ca0f8357b57b309e3693d45a4239 188 PIRSF PIRSF006806 1 183 1.1E-38 T 28-03-2018 IPR002698 5-formyltetrahydrofolate cyclo-ligase ALX04_RS02585 0756ca0f8357b57b309e3693d45a4239 188 Pfam PF01812 5-formyltetrahydrofolate cyclo-ligase family 3 179 1.8E-37 T 28-03-2018 IPR002698 5-formyltetrahydrofolate cyclo-ligase ALX04_RS02585 0756ca0f8357b57b309e3693d45a4239 188 SUPERFAMILY SSF100950 2 179 2.65E-46 T 28-03-2018 ALX04_RS02585 0756ca0f8357b57b309e3693d45a4239 188 Gene3D G3DSA:3.40.50.10420 1 182 2.8E-47 T 28-03-2018 ALX04_RS02585 0756ca0f8357b57b309e3693d45a4239 188 TIGRFAM TIGR02727 MTHFS_bact: 5-formyltetrahydrofolate cyclo-ligase 3 178 4.4E-44 T 28-03-2018 IPR002698 5-formyltetrahydrofolate cyclo-ligase ALX04_RS06710 ea50bf27cebf565d99b8b48527dd1611 366 Gene3D G3DSA:3.40.50.450 208 359 3.9E-19 T 28-03-2018 ALX04_RS06290 b54104d7de0eb67b60461e6b6afbcac8 334 SUPERFAMILY SSF53822 61 333 1.19E-60 T 28-03-2018 IPR028082 Periplasmic binding protein-like I ALX04_RS06290 b54104d7de0eb67b60461e6b6afbcac8 334 Gene3D G3DSA:1.10.260.40 2 53 4.8E-22 T 28-03-2018 ALX04_RS06290 b54104d7de0eb67b60461e6b6afbcac8 334 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 13 23 2.5E-5 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 ALX04_RS06290 b54104d7de0eb67b60461e6b6afbcac8 334 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 3 13 2.5E-5 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 ALX04_RS06290 b54104d7de0eb67b60461e6b6afbcac8 334 SUPERFAMILY SSF47413 1 60 2.29E-17 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 ALX04_RS06290 b54104d7de0eb67b60461e6b6afbcac8 334 Pfam PF00532 Periplasmic binding proteins and sugar binding domain of LacI family 61 321 3.8E-32 T 28-03-2018 IPR001761 Periplasmic binding protein/LacI sugar binding domain ALX04_RS06290 b54104d7de0eb67b60461e6b6afbcac8 334 Gene3D G3DSA:3.40.50.2300 173 318 3.4E-34 T 28-03-2018 ALX04_RS06290 b54104d7de0eb67b60461e6b6afbcac8 334 Pfam PF00356 Bacterial regulatory proteins, lacI family 3 47 2.2E-18 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 ALX04_RS06290 b54104d7de0eb67b60461e6b6afbcac8 334 Gene3D G3DSA:3.40.50.2300 54 172 3.5E-30 T 28-03-2018 ALX04_RS06290 b54104d7de0eb67b60461e6b6afbcac8 334 SMART SM00354 1 71 8.5E-28 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 ALX04_RS10470 dbaad0209286990d11ea21fc262f896d 101 Gene3D G3DSA:3.40.50.10400 7 101 2.6E-6 T 28-03-2018 IPR027269 Hypothetical PA1492 domain ALX04_RS14070 8651bbffa1f9b5875b3215ba428ca6b6 492 PIRSF PIRSF000484 6 482 1.8E-153 T 28-03-2018 IPR007229 Nicotinate phosphoribosyltransferase family KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|Reactome: R-HSA-197264 ALX04_RS14070 8651bbffa1f9b5875b3215ba428ca6b6 492 Gene3D G3DSA:3.20.140.10 7 390 1.0E-127 T 28-03-2018 ALX04_RS14070 8651bbffa1f9b5875b3215ba428ca6b6 492 SUPERFAMILY SSF54675 5 140 1.31E-52 T 28-03-2018 ALX04_RS14070 8651bbffa1f9b5875b3215ba428ca6b6 492 TIGRFAM TIGR01513 NAPRTase_put: nicotinate phosphoribosyltransferase 11 468 3.2E-186 T 28-03-2018 IPR006405 Nicotinate phosphoribosyltransferase pncB-type GO:0004516|GO:0019358 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|Reactome: R-HSA-197264|Reactome: R-HSA-6798695 ALX04_RS14070 8651bbffa1f9b5875b3215ba428ca6b6 492 Pfam PF04095 Nicotinate phosphoribosyltransferase (NAPRTase) family 158 340 9.5E-10 T 28-03-2018 IPR007229 Nicotinate phosphoribosyltransferase family KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|Reactome: R-HSA-197264 ALX04_RS14070 8651bbffa1f9b5875b3215ba428ca6b6 492 SUPERFAMILY SSF51690 141 480 2.21E-131 T 28-03-2018 IPR002638 Quinolinate phosphoribosyl transferase, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 ALX04_RS06280 b95ab27632f09d945d0730b49555ce2f 265 Pfam PF03609 PTS system sorbose-specific iic component 6 236 3.1E-65 T 28-03-2018 IPR004700 Phosphotransferase system, mannose/fructose/sorbose family, IIC subunit GO:0009401|GO:0016021 ALX04_RS02265 80822d7dd4bcfa417eacc1e008b31103 265 Gene3D G3DSA:3.40.50.300 1 255 2.8E-40 T 28-03-2018 ALX04_RS02265 80822d7dd4bcfa417eacc1e008b31103 265 SMART SM00382 34 262 3.8E-5 T 28-03-2018 IPR003593 AAA+ ATPase domain ALX04_RS02265 80822d7dd4bcfa417eacc1e008b31103 265 Pfam PF00005 ABC transporter 25 177 6.7E-21 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 ALX04_RS02265 80822d7dd4bcfa417eacc1e008b31103 265 TIGRFAM TIGR01978 sufC: FeS assembly ATPase SufC 4 248 1.2E-104 T 28-03-2018 IPR010230 FeS cluster assembly SUF system, ATPase SufC GO:0005524|GO:0006810 ALX04_RS02265 80822d7dd4bcfa417eacc1e008b31103 265 SUPERFAMILY SSF52540 4 237 3.41E-39 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase ALX04_RS02265 80822d7dd4bcfa417eacc1e008b31103 265 ProSitePatterns PS00211 ABC transporters family signature. 152 166 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 ALX04_RS08545 ae12f81d21a1fa9aea36a9b0ba2add2b 165 Pfam PF00583 Acetyltransferase (GNAT) family 31 115 8.1E-12 T 28-03-2018 IPR000182 GNAT domain GO:0008080 ALX04_RS08545 ae12f81d21a1fa9aea36a9b0ba2add2b 165 Gene3D G3DSA:3.40.630.30 1 154 3.7E-29 T 28-03-2018 ALX04_RS08545 ae12f81d21a1fa9aea36a9b0ba2add2b 165 SUPERFAMILY SSF55729 13 147 6.25E-25 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase ALX04_RS10390 75eb5a99df3bb21ef05c9682083a6a21 273 Pfam PF13353 4Fe-4S single cluster domain 30 166 1.3E-20 T 28-03-2018 ALX04_RS10390 75eb5a99df3bb21ef05c9682083a6a21 273 TIGRFAM TIGR02493 PFLA: pyruvate formate-lyase 1-activating enzyme 20 257 9.3E-88 T 28-03-2018 IPR012838 Pyruvate formate-lyase activating enzyme GO:0043365|GO:0055114 ALX04_RS10390 75eb5a99df3bb21ef05c9682083a6a21 273 Pfam PF04055 Radical SAM superfamily 40 197 6.4E-25 T 28-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 ALX04_RS10390 75eb5a99df3bb21ef05c9682083a6a21 273 SUPERFAMILY SSF102114 37 229 3.92E-25 T 28-03-2018 ALX04_RS10390 75eb5a99df3bb21ef05c9682083a6a21 273 ProSitePatterns PS01087 Radical activating enzymes signature. 32 53 - T 28-03-2018 IPR001989 Radical-activating enzyme, conserved site GO:0016491|GO:0051539|GO:0055114 ALX04_RS10390 75eb5a99df3bb21ef05c9682083a6a21 273 Gene3D G3DSA:3.80.30.10 81 264 5.0E-36 T 28-03-2018 ALX04_RS10390 75eb5a99df3bb21ef05c9682083a6a21 273 PIRSF PIRSF000371 10 61 7.6E-15 T 28-03-2018 IPR012839 Organic radical enzyme activase GO:0016491|GO:0055114 ALX04_RS10390 75eb5a99df3bb21ef05c9682083a6a21 273 PIRSF PIRSF000371 58 265 1.0E-39 T 28-03-2018 IPR012839 Organic radical enzyme activase GO:0016491|GO:0055114 ALX04_RS08685 ac9d8fef699aa219d1946501e18ce6a8 298 SUPERFAMILY SSF47413 3 65 5.25E-10 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 ALX04_RS08685 ac9d8fef699aa219d1946501e18ce6a8 298 TIGRFAM TIGR01716 RGG_Cterm: transcriptional activator, Rgg/GadR/MutR family, C-terminal domain 65 251 4.2E-13 T 28-03-2018 IPR010057 Transcription activator MutR, C-terminal ALX04_RS08685 ac9d8fef699aa219d1946501e18ce6a8 298 Gene3D G3DSA:1.10.260.40 1 144 6.7E-7 T 28-03-2018 ALX04_RS14325 da8267dacff72415cb0d7563abec5f81 860 Gene3D G3DSA:3.40.630.30 644 823 2.8E-12 T 28-03-2018 ALX04_RS14325 da8267dacff72415cb0d7563abec5f81 860 Pfam PF09924 Uncharacterised conserved protein (DUF2156) 536 830 1.2E-87 T 28-03-2018 IPR024320 Phosphatidylglycerol lysyltransferase, C-terminal ALX04_RS14325 da8267dacff72415cb0d7563abec5f81 860 SUPERFAMILY SSF55729 654 833 6.15E-8 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase ALX04_RS14325 da8267dacff72415cb0d7563abec5f81 860 Pfam PF03706 Lysylphosphatidylglycerol synthase TM region 20 297 1.7E-9 T 28-03-2018 IPR022791 Lysylphosphatidylglycerol synthetase/glycosyltransferase AglD ALX04_RS05475 f882c4a1bb5584635c164be4261af70a 288 Pfam PF01061 ABC-2 type transporter 2 220 4.8E-12 T 28-03-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 ALX04_RS09280 125e12033442ec6560c76d4ba030da83 378 Gene3D G3DSA:3.30.70.270 207 377 6.2E-42 T 28-03-2018 ALX04_RS09280 125e12033442ec6560c76d4ba030da83 378 Pfam PF00990 Diguanylate cyclase, GGDEF domain 214 373 3.1E-33 T 28-03-2018 IPR000160 GGDEF domain ALX04_RS09280 125e12033442ec6560c76d4ba030da83 378 SMART SM00267 204 378 1.1E-33 T 28-03-2018 IPR000160 GGDEF domain ALX04_RS09280 125e12033442ec6560c76d4ba030da83 378 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 213 376 3.0E-36 T 28-03-2018 IPR000160 GGDEF domain ALX04_RS09280 125e12033442ec6560c76d4ba030da83 378 SUPERFAMILY SSF55073 219 374 1.57E-36 T 28-03-2018 IPR029787 Nucleotide cyclase ALX04_RS11450 e62579f865f44140eb288cc0fa95d30a 294 Pfam PF06800 Sugar transport protein 7 294 4.3E-103 T 28-03-2018 IPR010651 Sugar transport protein GO:0015144|GO:0016021|GO:0034219 ALX04_RS11450 e62579f865f44140eb288cc0fa95d30a 294 SUPERFAMILY SSF103481 41 135 3.66E-6 T 28-03-2018 ALX04_RS12540 dfdc2d031fc8e62dae904386a0d4acd0 402 Pfam PF07690 Major Facilitator Superfamily 24 356 6.5E-31 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 ALX04_RS12540 dfdc2d031fc8e62dae904386a0d4acd0 402 Gene3D G3DSA:1.20.1250.20 211 396 8.2E-20 T 28-03-2018 ALX04_RS12540 dfdc2d031fc8e62dae904386a0d4acd0 402 SUPERFAMILY SSF103473 22 394 2.62E-42 T 28-03-2018 IPR020846 Major facilitator superfamily domain ALX04_RS12540 dfdc2d031fc8e62dae904386a0d4acd0 402 Gene3D G3DSA:1.20.1250.20 18 210 4.1E-21 T 28-03-2018 ALX04_RS12540 dfdc2d031fc8e62dae904386a0d4acd0 402 ProSitePatterns PS00217 Sugar transport proteins signature 2. 115 140 - T 28-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 ALX04_RS03890 56a34a87a0c2cf9cbad369e86dc8ea7e 261 Pfam PF01113 Dihydrodipicolinate reductase, N-terminus 2 124 8.9E-36 T 28-03-2018 IPR000846 Dihydrodipicolinate reductase, N-terminal GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 ALX04_RS03890 56a34a87a0c2cf9cbad369e86dc8ea7e 261 Pfam PF05173 Dihydrodipicolinate reductase, C-terminus 128 261 6.3E-30 T 28-03-2018 IPR022663 Dihydrodipicolinate reductase, C-terminal GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 ALX04_RS03890 56a34a87a0c2cf9cbad369e86dc8ea7e 261 SUPERFAMILY SSF55347 126 233 6.76E-39 T 28-03-2018 ALX04_RS03890 56a34a87a0c2cf9cbad369e86dc8ea7e 261 PIRSF PIRSF000161 1 261 1.6E-67 T 28-03-2018 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 ALX04_RS03890 56a34a87a0c2cf9cbad369e86dc8ea7e 261 Hamap MF_00102 4-hydroxy-tetrahydrodipicolinate reductase [dapB]. 2 258 27.326 T 28-03-2018 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 ALX04_RS03890 56a34a87a0c2cf9cbad369e86dc8ea7e 261 SUPERFAMILY SSF51735 2 150 3.57E-40 T 28-03-2018 IPR016040 NAD(P)-binding domain ALX04_RS03890 56a34a87a0c2cf9cbad369e86dc8ea7e 261 TIGRFAM TIGR00036 dapB: 4-hydroxy-tetrahydrodipicolinate reductase 2 261 3.7E-71 T 28-03-2018 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 ALX04_RS03890 56a34a87a0c2cf9cbad369e86dc8ea7e 261 Gene3D G3DSA:3.40.50.720 1 119 4.8E-32 T 28-03-2018 ALX04_RS03890 56a34a87a0c2cf9cbad369e86dc8ea7e 261 Gene3D G3DSA:3.30.360.10 126 230 9.6E-35 T 28-03-2018 ALX04_RS03890 56a34a87a0c2cf9cbad369e86dc8ea7e 261 ProSitePatterns PS01298 Dihydrodipicolinate reductase signature. 146 163 - T 28-03-2018 IPR022664 Dihydrodipicolinate reductase, conserved site GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 ALX04_RS02340 994f00533be27a4a1f3231fbd81bc891 173 ProSitePatterns PS00938 Initiation factor 3 signature. 60 73 - T 28-03-2018 IPR019813 Translation initiation factor 3, conserved site GO:0003743|GO:0006413 ALX04_RS02340 994f00533be27a4a1f3231fbd81bc891 173 SUPERFAMILY SSF54364 8 80 3.27E-28 T 28-03-2018 IPR019814 Translation initiation factor 3, N-terminal GO:0003743|GO:0006413 Reactome: R-HSA-5368286 ALX04_RS02340 994f00533be27a4a1f3231fbd81bc891 173 Hamap MF_00080 Translation initiation factor IF-3 [infC]. 3 172 29.871 T 28-03-2018 IPR001288 Translation initiation factor 3 GO:0003743|GO:0006413 Reactome: R-HSA-5368286 ALX04_RS02340 994f00533be27a4a1f3231fbd81bc891 173 Pfam PF05198 Translation initiation factor IF-3, N-terminal domain 9 78 3.1E-31 T 28-03-2018 IPR019814 Translation initiation factor 3, N-terminal GO:0003743|GO:0006413 Reactome: R-HSA-5368286 ALX04_RS02340 994f00533be27a4a1f3231fbd81bc891 173 Gene3D G3DSA:3.30.110.10 81 173 7.8E-34 T 28-03-2018 ALX04_RS02340 994f00533be27a4a1f3231fbd81bc891 173 Gene3D G3DSA:3.10.20.80 4 80 5.7E-30 T 28-03-2018 ALX04_RS02340 994f00533be27a4a1f3231fbd81bc891 173 TIGRFAM TIGR00168 infC: translation initiation factor IF-3 9 171 1.5E-68 T 28-03-2018 IPR001288 Translation initiation factor 3 GO:0003743|GO:0006413 Reactome: R-HSA-5368286 ALX04_RS02340 994f00533be27a4a1f3231fbd81bc891 173 Pfam PF00707 Translation initiation factor IF-3, C-terminal domain 85 170 4.4E-36 T 28-03-2018 IPR019815 Translation initiation factor 3, C-terminal GO:0006413 Reactome: R-HSA-5368286 ALX04_RS02340 994f00533be27a4a1f3231fbd81bc891 173 SUPERFAMILY SSF55200 84 172 7.46E-32 T 28-03-2018 IPR019815 Translation initiation factor 3, C-terminal GO:0006413 Reactome: R-HSA-5368286 ALX04_RS08530 2d6085bbc7f191959051e5599d7a1724 205 Gene3D G3DSA:2.10.109.10 23 205 4.5E-35 T 28-03-2018 ALX04_RS08530 2d6085bbc7f191959051e5599d7a1724 205 Pfam PF10502 Signal peptidase, peptidase S26 152 189 1.2E-5 T 28-03-2018 IPR019533 Peptidase S26 ALX04_RS08530 2d6085bbc7f191959051e5599d7a1724 205 ProSitePatterns PS00760 Signal peptidases I lysine active site. 83 95 - T 28-03-2018 IPR019757 Peptidase S26A, signal peptidase I, lysine active site GO:0008236|GO:0016021 ALX04_RS08530 2d6085bbc7f191959051e5599d7a1724 205 SUPERFAMILY SSF51306 25 194 8.63E-47 T 28-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C ALX04_RS08530 2d6085bbc7f191959051e5599d7a1724 205 Pfam PF00717 Peptidase S24-like 33 106 6.5E-14 T 28-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C ALX04_RS08530 2d6085bbc7f191959051e5599d7a1724 205 TIGRFAM TIGR02227 sigpep_I_bact: signal peptidase I 11 193 2.4E-41 T 28-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 ALX04_RS08530 2d6085bbc7f191959051e5599d7a1724 205 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 155 174 1.1E-17 T 28-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 ALX04_RS08530 2d6085bbc7f191959051e5599d7a1724 205 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 81 93 1.1E-17 T 28-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 ALX04_RS08530 2d6085bbc7f191959051e5599d7a1724 205 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 27 43 1.1E-17 T 28-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 ALX04_RS08530 2d6085bbc7f191959051e5599d7a1724 205 ProSitePatterns PS00761 Signal peptidases I signature 3. 160 173 - T 28-03-2018 IPR019758 Peptidase S26A, signal peptidase I, conserved site GO:0008236|GO:0016021 ALX04_RS07200 8e8beb920f560a495b70d4982fae2e7d 662 Pfam PF00367 phosphotransferase system, EIIB 411 444 4.4E-13 T 28-03-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 ALX04_RS07200 8e8beb920f560a495b70d4982fae2e7d 662 Gene3D G3DSA:3.30.1360.60 407 483 6.2E-24 T 28-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 ALX04_RS07200 8e8beb920f560a495b70d4982fae2e7d 662 TIGRFAM TIGR00826 EIIB_glc: PTS system, glucose-like IIB component 370 469 2.3E-15 T 28-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 ALX04_RS07200 8e8beb920f560a495b70d4982fae2e7d 662 Gene3D G3DSA:2.70.70.10 504 661 1.8E-54 T 28-03-2018 ALX04_RS07200 8e8beb920f560a495b70d4982fae2e7d 662 ProSitePatterns PS01035 PTS EIIB domains cysteine phosphorylation site signature. 422 439 - T 28-03-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 ALX04_RS07200 8e8beb920f560a495b70d4982fae2e7d 662 ProSitePatterns PS00371 PTS EIIA domains phosphorylation site signature 1. 579 591 - T 28-03-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 ALX04_RS07200 8e8beb920f560a495b70d4982fae2e7d 662 TIGRFAM TIGR00830 PTBA: PTS system, glucose subfamily, IIA component 518 637 3.5E-41 T 28-03-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 ALX04_RS07200 8e8beb920f560a495b70d4982fae2e7d 662 Pfam PF00358 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 517 640 4.6E-47 T 28-03-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 ALX04_RS07200 8e8beb920f560a495b70d4982fae2e7d 662 SUPERFAMILY SSF51261 514 657 3.14E-49 T 28-03-2018 IPR011055 Duplicated hybrid motif ALX04_RS07200 8e8beb920f560a495b70d4982fae2e7d 662 TIGRFAM TIGR01998 PTS-II-BC-nag: PTS system, N-acetylglucosamine-specific IIBC component 1 480 4.4E-215 T 28-03-2018 IPR010974 Phosphotransferase system, N-acetylglucosamine-specific IIBC component GO:0008982|GO:0009401|GO:0015572|GO:0016021|GO:0019866 ALX04_RS07200 8e8beb920f560a495b70d4982fae2e7d 662 SUPERFAMILY SSF55604 409 483 1.44E-16 T 28-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 ALX04_RS07200 8e8beb920f560a495b70d4982fae2e7d 662 Pfam PF02378 Phosphotransferase system, EIIC 10 311 8.2E-64 T 28-03-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 ALX04_RS14050 0a184f89242df73110773da5db599c1d 263 ProSitePatterns PS00521 Delta 1-pyrroline-5-carboxylate reductase signature. 218 240 - T 28-03-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344 ALX04_RS14050 0a184f89242df73110773da5db599c1d 263 TIGRFAM TIGR00112 proC: pyrroline-5-carboxylate reductase 3 258 3.6E-70 T 28-03-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344 ALX04_RS14050 0a184f89242df73110773da5db599c1d 263 Hamap MF_01925 Pyrroline-5-carboxylate reductase [proC]. 1 262 23.61 T 28-03-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344 ALX04_RS14050 0a184f89242df73110773da5db599c1d 263 Gene3D G3DSA:1.10.3730.10 156 262 1.9E-31 T 28-03-2018 ALX04_RS14050 0a184f89242df73110773da5db599c1d 263 Gene3D G3DSA:3.40.50.720 1 155 5.7E-27 T 28-03-2018 ALX04_RS14050 0a184f89242df73110773da5db599c1d 263 SUPERFAMILY SSF51735 1 153 7.18E-30 T 28-03-2018 IPR016040 NAD(P)-binding domain ALX04_RS14050 0a184f89242df73110773da5db599c1d 263 Pfam PF14748 Pyrroline-5-carboxylate reductase dimerisation 158 258 1.8E-31 T 28-03-2018 IPR029036 Pyrroline-5-carboxylate reductase, dimerisation domain KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 ALX04_RS14050 0a184f89242df73110773da5db599c1d 263 PIRSF PIRSF000193 1 263 2.7E-65 T 28-03-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344 ALX04_RS14050 0a184f89242df73110773da5db599c1d 263 SUPERFAMILY SSF48179 158 258 1.67E-28 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 ALX04_RS14050 0a184f89242df73110773da5db599c1d 263 Pfam PF03807 NADP oxidoreductase coenzyme F420-dependent 2 95 2.0E-17 T 28-03-2018 IPR028939 Pyrroline-5-carboxylate reductase, catalytic, N-terminal ALX04_RS08700 8119e0c64eaf2584fe4402348b64b44c 189 Pfam PF12464 Maltose acetyltransferase 12 59 5.6E-8 T 28-03-2018 IPR024688 Maltose/galactoside acetyltransferase GO:0016407 ALX04_RS08700 8119e0c64eaf2584fe4402348b64b44c 189 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 132 166 2.7E-10 T 28-03-2018 IPR001451 Hexapeptide repeat ALX04_RS08700 8119e0c64eaf2584fe4402348b64b44c 189 SUPERFAMILY SSF51161 55 186 1.52E-43 T 28-03-2018 IPR011004 Trimeric LpxA-like ALX04_RS08700 8119e0c64eaf2584fe4402348b64b44c 189 SMART SM01266 9 60 6.2E-7 T 28-03-2018 IPR024688 Maltose/galactoside acetyltransferase GO:0016407 ALX04_RS08700 8119e0c64eaf2584fe4402348b64b44c 189 Gene3D G3DSA:2.160.10.10 1 189 4.5E-46 T 28-03-2018 ALX04_RS11065 412c0afd976a7de7ae5babc0731b9405 318 Pfam PF02424 ApbE family 15 294 3.7E-72 T 28-03-2018 IPR024932 Flavin transferase ApbE GO:0017013 ALX04_RS11065 412c0afd976a7de7ae5babc0731b9405 318 Gene3D G3DSA:3.10.520.10 3 309 1.1E-50 T 28-03-2018 ALX04_RS11065 412c0afd976a7de7ae5babc0731b9405 318 PIRSF PIRSF006268 2 313 6.9E-93 T 28-03-2018 IPR024932 Flavin transferase ApbE GO:0017013 ALX04_RS11065 412c0afd976a7de7ae5babc0731b9405 318 SUPERFAMILY SSF143631 8 309 3.4E-85 T 28-03-2018 IPR003374 ApbE-like domain ALX04_RS02205 e29cf621d7170baba3cc5c6181e63d21 150 Pfam PF01230 HIT domain 20 116 2.1E-20 T 28-03-2018 IPR001310 Histidine triad (HIT) protein ALX04_RS02205 e29cf621d7170baba3cc5c6181e63d21 150 PRINTS PR00332 Histidine triad family signature 13 29 1.2E-16 T 28-03-2018 IPR001310 Histidine triad (HIT) protein ALX04_RS02205 e29cf621d7170baba3cc5c6181e63d21 150 PRINTS PR00332 Histidine triad family signature 34 52 1.2E-16 T 28-03-2018 IPR001310 Histidine triad (HIT) protein ALX04_RS02205 e29cf621d7170baba3cc5c6181e63d21 150 PRINTS PR00332 Histidine triad family signature 102 112 1.2E-16 T 28-03-2018 IPR001310 Histidine triad (HIT) protein ALX04_RS02205 e29cf621d7170baba3cc5c6181e63d21 150 ProSitePatterns PS00892 HIT domain signature. 95 113 - T 28-03-2018 IPR019808 Histidine triad, conserved site ALX04_RS02205 e29cf621d7170baba3cc5c6181e63d21 150 Gene3D G3DSA:3.30.428.10 2 149 1.5E-33 T 28-03-2018 IPR011146 HIT-like domain GO:0003824 ALX04_RS02205 e29cf621d7170baba3cc5c6181e63d21 150 SUPERFAMILY SSF54197 10 146 1.5E-39 T 28-03-2018 IPR011146 HIT-like domain GO:0003824 ALX04_RS11165 6422ce9135b2faae5b6bbbbad147297f 281 Pfam PF00874 PRD domain 181 275 2.0E-15 T 28-03-2018 IPR011608 PRD domain GO:0006355 ALX04_RS11165 6422ce9135b2faae5b6bbbbad147297f 281 Pfam PF00874 PRD domain 75 160 3.6E-20 T 28-03-2018 IPR011608 PRD domain GO:0006355 ALX04_RS11165 6422ce9135b2faae5b6bbbbad147297f 281 Gene3D G3DSA:2.30.24.10 1 63 4.0E-20 T 28-03-2018 IPR004341 CAT RNA-binding domain GO:0003723 ALX04_RS11165 6422ce9135b2faae5b6bbbbad147297f 281 SUPERFAMILY SSF50151 1 54 2.49E-15 T 28-03-2018 IPR004341 CAT RNA-binding domain GO:0003723 ALX04_RS11165 6422ce9135b2faae5b6bbbbad147297f 281 Gene3D G3DSA:1.10.1790.10 64 166 2.6E-22 T 28-03-2018 IPR011608 PRD domain GO:0006355 ALX04_RS11165 6422ce9135b2faae5b6bbbbad147297f 281 SMART SM01061 1 58 5.6E-24 T 28-03-2018 IPR004341 CAT RNA-binding domain GO:0003723 ALX04_RS11165 6422ce9135b2faae5b6bbbbad147297f 281 SUPERFAMILY SSF63520 172 277 2.62E-22 T 28-03-2018 IPR011608 PRD domain GO:0006355 ALX04_RS11165 6422ce9135b2faae5b6bbbbad147297f 281 SUPERFAMILY SSF63520 56 161 9.16E-25 T 28-03-2018 IPR011608 PRD domain GO:0006355 ALX04_RS11165 6422ce9135b2faae5b6bbbbad147297f 281 Gene3D G3DSA:1.10.1790.10 168 280 3.3E-21 T 28-03-2018 IPR011608 PRD domain GO:0006355 ALX04_RS11165 6422ce9135b2faae5b6bbbbad147297f 281 Pfam PF03123 CAT RNA binding domain 1 51 2.5E-19 T 28-03-2018 IPR004341 CAT RNA-binding domain GO:0003723 ALX04_RS14220 e71cba925ef7da0343186223a564dc6e 178 Gene3D G3DSA:2.70.40.10 1 165 3.7E-33 T 28-03-2018 ALX04_RS14220 e71cba925ef7da0343186223a564dc6e 178 Pfam PF00692 dUTPase 68 176 9.8E-14 T 28-03-2018 IPR029054 dUTPase-like ALX04_RS14220 e71cba925ef7da0343186223a564dc6e 178 SUPERFAMILY SSF51283 3 40 2.22E-31 T 28-03-2018 IPR029054 dUTPase-like ALX04_RS14220 e71cba925ef7da0343186223a564dc6e 178 SUPERFAMILY SSF51283 71 177 2.22E-31 T 28-03-2018 IPR029054 dUTPase-like ALX04_RS10995 221ad5e92106cf09ac61c12a6bd176cc 195 SUPERFAMILY SSF47413 48 99 6.76E-10 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 ALX04_RS10995 221ad5e92106cf09ac61c12a6bd176cc 195 Pfam PF01381 Helix-turn-helix 55 98 5.1E-7 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 ALX04_RS10995 221ad5e92106cf09ac61c12a6bd176cc 195 SMART SM00530 54 108 6.4E-4 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 ALX04_RS10995 221ad5e92106cf09ac61c12a6bd176cc 195 Gene3D G3DSA:1.10.3100.10 45 189 3.5E-12 T 28-03-2018 IPR027910 YdiL-like domain ALX04_RS12305 7a934122f236b1aa047cbf7d093dfbad 320 Gene3D G3DSA:3.40.50.2300 162 291 1.0E-27 T 28-03-2018 ALX04_RS12305 7a934122f236b1aa047cbf7d093dfbad 320 Gene3D G3DSA:3.40.50.2300 55 161 2.3E-16 T 28-03-2018 ALX04_RS12305 7a934122f236b1aa047cbf7d093dfbad 320 Pfam PF13377 Periplasmic binding protein-like domain 157 303 5.4E-24 T 28-03-2018 ALX04_RS12305 7a934122f236b1aa047cbf7d093dfbad 320 Gene3D G3DSA:1.10.260.40 2 54 4.9E-21 T 28-03-2018 ALX04_RS12305 7a934122f236b1aa047cbf7d093dfbad 320 ProSitePatterns PS00356 LacI-type HTH domain signature. 4 22 - T 28-03-2018 ALX04_RS12305 7a934122f236b1aa047cbf7d093dfbad 320 SMART SM00354 1 71 4.0E-27 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 ALX04_RS12305 7a934122f236b1aa047cbf7d093dfbad 320 SUPERFAMILY SSF53822 58 319 2.36E-49 T 28-03-2018 IPR028082 Periplasmic binding protein-like I ALX04_RS12305 7a934122f236b1aa047cbf7d093dfbad 320 Pfam PF00356 Bacterial regulatory proteins, lacI family 3 48 3.4E-19 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 ALX04_RS12305 7a934122f236b1aa047cbf7d093dfbad 320 SUPERFAMILY SSF47413 1 59 5.06E-17 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 ALX04_RS12305 7a934122f236b1aa047cbf7d093dfbad 320 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 3 13 2.2E-5 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 ALX04_RS12305 7a934122f236b1aa047cbf7d093dfbad 320 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 13 23 2.2E-5 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 ALX04_RS09935 b647f0a91a5f04bea9be00d8f9817e3c 410 Gene3D G3DSA:3.40.640.10 45 297 5.6E-51 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 ALX04_RS09935 b647f0a91a5f04bea9be00d8f9817e3c 410 Gene3D G3DSA:3.90.1150.10 298 395 6.1E-22 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 ALX04_RS09935 b647f0a91a5f04bea9be00d8f9817e3c 410 SUPERFAMILY SSF53383 3 393 8.48E-99 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase ALX04_RS09935 b647f0a91a5f04bea9be00d8f9817e3c 410 Pfam PF00155 Aminotransferase class I and II 43 387 3.5E-36 T 28-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 ALX04_RS03065 ed4a96f134b5f62fc776524d5ed48141 281 SUPERFAMILY SSF52096 27 275 2.2E-63 T 28-03-2018 IPR029045 ClpP/crotonase-like domain ALX04_RS03065 ed4a96f134b5f62fc776524d5ed48141 281 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 158 176 4.1E-34 T 28-03-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 ALX04_RS03065 ed4a96f134b5f62fc776524d5ed48141 281 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 124 138 4.1E-34 T 28-03-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 ALX04_RS03065 ed4a96f134b5f62fc776524d5ed48141 281 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 246 255 4.1E-34 T 28-03-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 ALX04_RS03065 ed4a96f134b5f62fc776524d5ed48141 281 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 195 212 4.1E-34 T 28-03-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 ALX04_RS03065 ed4a96f134b5f62fc776524d5ed48141 281 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 224 235 4.1E-34 T 28-03-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 ALX04_RS03065 ed4a96f134b5f62fc776524d5ed48141 281 Gene3D G3DSA:3.90.226.10 17 280 5.9E-59 T 28-03-2018 ALX04_RS03065 ed4a96f134b5f62fc776524d5ed48141 281 Hamap MF_01395 Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta, chloroplastic [accD]. 13 276 33.471 T 28-03-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 ALX04_RS03065 ed4a96f134b5f62fc776524d5ed48141 281 Pfam PF01039 Carboxyl transferase domain 91 234 1.7E-15 T 28-03-2018 IPR034733 Acetyl-CoA carboxylase KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388|Reactome: R-HSA-196780 ALX04_RS09070 c9d99e7f3967bd97115c15bbbefb75f4 502 Gene3D G3DSA:2.60.40.10 168 268 1.8E-5 T 28-03-2018 IPR013783 Immunoglobulin-like fold ALX04_RS10970 a00739957a07d289a6dcd485ad51ef6c 425 SUPERFAMILY SSF103473 5 409 7.85E-46 T 28-03-2018 IPR020846 Major facilitator superfamily domain ALX04_RS10970 a00739957a07d289a6dcd485ad51ef6c 425 Gene3D G3DSA:1.20.1250.20 210 419 9.4E-13 T 28-03-2018 ALX04_RS10970 a00739957a07d289a6dcd485ad51ef6c 425 Pfam PF07690 Major Facilitator Superfamily 17 368 5.8E-21 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 ALX04_RS10970 a00739957a07d289a6dcd485ad51ef6c 425 Gene3D G3DSA:1.20.1250.20 3 200 1.8E-22 T 28-03-2018 ALX04_RS10285 fedd8eaa95cbf46853e9eb8f08c856ec 212 SMART SM00530 6 61 8.1E-13 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 ALX04_RS10285 fedd8eaa95cbf46853e9eb8f08c856ec 212 SUPERFAMILY SSF47413 1 65 1.82E-16 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 ALX04_RS10285 fedd8eaa95cbf46853e9eb8f08c856ec 212 Gene3D G3DSA:1.10.3100.10 1 95 1.8E-18 T 28-03-2018 IPR027910 YdiL-like domain ALX04_RS10285 fedd8eaa95cbf46853e9eb8f08c856ec 212 Pfam PF01381 Helix-turn-helix 8 61 6.0E-11 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 ALX04_RS02140 e03641154fd3ade5a3952b1762d6a8b4 185 SUPERFAMILY SSF46689 6 64 4.05E-11 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 ALX04_RS02140 e03641154fd3ade5a3952b1762d6a8b4 185 Gene3D G3DSA:1.10.10.60 4 44 1.3E-9 T 28-03-2018 ALX04_RS02140 e03641154fd3ade5a3952b1762d6a8b4 185 Gene3D G3DSA:1.10.10.60 45 182 3.5E-7 T 28-03-2018 ALX04_RS02140 e03641154fd3ade5a3952b1762d6a8b4 185 Pfam PF00440 Bacterial regulatory proteins, tetR family 24 55 1.2E-5 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 ALX04_RS13690 c4d2647fd40d8548056ced9d8b61512c 186 Pfam PF04011 LemA family 5 184 2.6E-68 T 28-03-2018 IPR007156 LemA ALX04_RS13690 c4d2647fd40d8548056ced9d8b61512c 186 SUPERFAMILY SSF140478 24 173 5.89E-54 T 28-03-2018 IPR023353 LemA-like domain ALX04_RS13690 c4d2647fd40d8548056ced9d8b61512c 186 Gene3D G3DSA:1.20.1440.20 12 184 7.3E-56 T 28-03-2018 ALX04_RS08565 5e74725ef2847d08fc3df063c8a986f4 134 Gene3D G3DSA:3.10.450.50 11 134 2.6E-12 T 28-03-2018 ALX04_RS08565 5e74725ef2847d08fc3df063c8a986f4 134 SUPERFAMILY SSF54427 12 129 6.46E-12 T 28-03-2018 IPR032710 NTF2-like domain ALX04_RS08565 5e74725ef2847d08fc3df063c8a986f4 134 Pfam PF14534 Domain of unknown function (DUF4440) 18 126 3.5E-15 T 28-03-2018 IPR027843 Domain of unknown function DUF4440 ALX04_RS04655 019a31633b733cb90efcf7fc95acb3a6 240 Gene3D G3DSA:3.40.50.1000 1 28 0.24 T 28-03-2018 IPR023214 HAD-like domain ALX04_RS04655 019a31633b733cb90efcf7fc95acb3a6 240 SUPERFAMILY SSF56784 1 230 1.22E-43 T 28-03-2018 IPR023214 HAD-like domain ALX04_RS04655 019a31633b733cb90efcf7fc95acb3a6 240 Gene3D G3DSA:1.10.150.240 29 91 5.6E-5 T 28-03-2018 IPR023198 Phosphoglycolate phosphatase, domain 2 ALX04_RS04655 019a31633b733cb90efcf7fc95acb3a6 240 Pfam PF13419 Haloacid dehalogenase-like hydrolase 5 201 3.7E-29 T 28-03-2018 IPR023214 HAD-like domain ALX04_RS04655 019a31633b733cb90efcf7fc95acb3a6 240 Gene3D G3DSA:3.40.50.1000 92 239 4.1E-28 T 28-03-2018 IPR023214 HAD-like domain ALX04_RS04655 019a31633b733cb90efcf7fc95acb3a6 240 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 145 161 5.8E-9 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 ALX04_RS04655 019a31633b733cb90efcf7fc95acb3a6 240 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 112 125 5.8E-9 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 ALX04_RS04655 019a31633b733cb90efcf7fc95acb3a6 240 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 2 13 5.8E-9 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 ALX04_RS04655 019a31633b733cb90efcf7fc95acb3a6 240 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 191 204 5.8E-9 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 ALX04_RS04655 019a31633b733cb90efcf7fc95acb3a6 240 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 116 196 1.6E-9 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 ALX04_RS10035 e7f16e38960b9da96e7f2bc4f0557111 287 Pfam PF00480 ROK family 4 284 2.6E-63 T 28-03-2018 IPR000600 ROK family Reactome: R-HSA-4085001 ALX04_RS10035 e7f16e38960b9da96e7f2bc4f0557111 287 Gene3D G3DSA:3.30.420.40 3 114 2.9E-18 T 28-03-2018 ALX04_RS10035 e7f16e38960b9da96e7f2bc4f0557111 287 SUPERFAMILY SSF53067 1 285 1.09E-41 T 28-03-2018 ALX04_RS10035 e7f16e38960b9da96e7f2bc4f0557111 287 Gene3D G3DSA:3.30.420.40 115 287 3.4E-29 T 28-03-2018 ALX04_RS06255 de7ae8aa01ff0a23e983413f5493f3b1 208 Pfam PF07853 Protein of unknown function (DUF1648) 13 60 1.7E-12 T 28-03-2018 IPR012867 Domain of unknown function DUF1648 ALX04_RS09425 221b9ab4b64dcba9c93e9ae451e5414a 124 Pfam PF13473 Cupredoxin-like domain 16 123 2.2E-22 T 28-03-2018 IPR028096 EfeO-type cupredoxin-like domain ALX04_RS09425 221b9ab4b64dcba9c93e9ae451e5414a 124 SUPERFAMILY SSF49503 15 123 2.73E-12 T 28-03-2018 IPR008972 Cupredoxin ALX04_RS09425 221b9ab4b64dcba9c93e9ae451e5414a 124 Gene3D G3DSA:2.60.40.420 27 124 3.3E-6 T 28-03-2018 IPR008972 Cupredoxin ALX04_RS15060 593e2c41575e1b9c8fb9e83843084953 139 SUPERFAMILY SSF82784 9 138 1.83E-26 T 28-03-2018 IPR003718 OsmC/Ohr family ALX04_RS15060 593e2c41575e1b9c8fb9e83843084953 139 Pfam PF02566 OsmC-like protein 46 136 1.9E-12 T 28-03-2018 IPR003718 OsmC/Ohr family ALX04_RS15060 593e2c41575e1b9c8fb9e83843084953 139 Gene3D G3DSA:3.30.300.20 7 139 3.9E-22 T 28-03-2018 IPR015946 K homology domain-like, alpha/beta ALX04_RS06035 21088b8cf29e367f99590b9587dbb455 127 TIGRFAM TIGR00739 yajC: preprotein translocase, YajC subunit 4 84 2.9E-22 T 28-03-2018 IPR003849 Preprotein translocase YajC ALX04_RS06035 21088b8cf29e367f99590b9587dbb455 127 Pfam PF02699 Preprotein translocase subunit 6 83 9.1E-26 T 28-03-2018 IPR003849 Preprotein translocase YajC ALX04_RS06035 21088b8cf29e367f99590b9587dbb455 127 PRINTS PR01853 Bacterial YajC preprotein translocase signature 4 24 5.6E-12 T 28-03-2018 IPR003849 Preprotein translocase YajC ALX04_RS06035 21088b8cf29e367f99590b9587dbb455 127 PRINTS PR01853 Bacterial YajC preprotein translocase signature 24 42 5.6E-12 T 28-03-2018 IPR003849 Preprotein translocase YajC ALX04_RS06035 21088b8cf29e367f99590b9587dbb455 127 SMART SM01323 2 85 3.3E-38 T 28-03-2018 IPR003849 Preprotein translocase YajC ALX04_RS06785 a094914543a79b1bf5fcf2c1c21b7d72 170 Gene3D G3DSA:1.10.260.40 5 170 3.4E-9 T 28-03-2018 ALX04_RS14310 c589c68168580cc26bc54360a0661b4a 122 SUPERFAMILY SSF48300 3 51 2.09E-12 T 28-03-2018 IPR008932 Ribosomal protein L7/L12, oligomerisation GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 ALX04_RS14310 c589c68168580cc26bc54360a0661b4a 122 Pfam PF00542 Ribosomal protein L7/L12 C-terminal domain 56 122 1.1E-26 T 28-03-2018 IPR013823 Ribosomal protein L7/L12, C-terminal GO:0003735|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 ALX04_RS14310 c589c68168580cc26bc54360a0661b4a 122 Gene3D G3DSA:1.20.5.710 3 52 9.9E-11 T 28-03-2018 ALX04_RS14310 c589c68168580cc26bc54360a0661b4a 122 ProDom PD001326 RIBOSOMAL L7/L12 50S RIBONUCLEOPROTEIN CHLOROPLAST L12 PLASTID DIRECT SEQUENCING PEPTIDE 57 122 2.0E-29 T 28-03-2018 IPR013823 Ribosomal protein L7/L12, C-terminal GO:0003735|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 ALX04_RS14310 c589c68168580cc26bc54360a0661b4a 122 Hamap MF_00368 50S ribosomal protein L7/L12 [rplL]. 2 122 21.194 T 28-03-2018 IPR000206 Ribosomal protein L7/L12 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 ALX04_RS14310 c589c68168580cc26bc54360a0661b4a 122 Pfam PF16320 Ribosomal protein L7/L12 dimerisation domain 5 51 7.9E-17 T 28-03-2018 IPR008932 Ribosomal protein L7/L12, oligomerisation GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 ALX04_RS14310 c589c68168580cc26bc54360a0661b4a 122 Gene3D G3DSA:3.30.1390.10 53 122 9.9E-27 T 28-03-2018 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like ALX04_RS14310 c589c68168580cc26bc54360a0661b4a 122 TIGRFAM TIGR00855 L12: ribosomal protein bL12 1 122 2.1E-39 T 28-03-2018 IPR000206 Ribosomal protein L7/L12 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 ALX04_RS14310 c589c68168580cc26bc54360a0661b4a 122 SUPERFAMILY SSF54736 56 122 8.2E-22 T 28-03-2018 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like ALX04_RS00520 7963e6cebe7703169add8158b10e294e 330 ProSitePatterns PS00444 Polyprenyl synthases signature 2. 211 223 - T 28-03-2018 IPR033749 Polyprenyl synthetase, conserved site ALX04_RS00520 7963e6cebe7703169add8158b10e294e 330 SUPERFAMILY SSF48576 6 329 4.16E-75 T 28-03-2018 IPR008949 Isoprenoid synthase domain ALX04_RS00520 7963e6cebe7703169add8158b10e294e 330 ProSitePatterns PS00723 Polyprenyl synthases signature 1. 88 102 - T 28-03-2018 IPR033749 Polyprenyl synthetase, conserved site ALX04_RS00520 7963e6cebe7703169add8158b10e294e 330 Pfam PF00348 Polyprenyl synthetase 41 265 1.6E-56 T 28-03-2018 IPR000092 Polyprenyl synthetase GO:0008299 ALX04_RS00520 7963e6cebe7703169add8158b10e294e 330 Gene3D G3DSA:1.10.600.10 12 330 2.4E-76 T 28-03-2018 IPR008949 Isoprenoid synthase domain ALX04_RS16015 ebde50d9d8793fc68c82750aaaa9fe53 233 SMART SM00448 3 114 1.7E-42 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 ALX04_RS16015 ebde50d9d8793fc68c82750aaaa9fe53 233 Pfam PF00486 Transcriptional regulatory protein, C terminal 154 228 1.3E-20 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 ALX04_RS16015 ebde50d9d8793fc68c82750aaaa9fe53 233 SUPERFAMILY SSF46894 133 228 5.95E-25 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 ALX04_RS16015 ebde50d9d8793fc68c82750aaaa9fe53 233 Gene3D G3DSA:1.10.10.10 125 232 5.7E-23 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS16015 ebde50d9d8793fc68c82750aaaa9fe53 233 Pfam PF00072 Response regulator receiver domain 5 115 4.8E-31 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 ALX04_RS16015 ebde50d9d8793fc68c82750aaaa9fe53 233 SUPERFAMILY SSF52172 2 126 9.68E-42 T 28-03-2018 IPR011006 CheY-like superfamily ALX04_RS16015 ebde50d9d8793fc68c82750aaaa9fe53 233 SMART SM00862 153 228 9.2E-17 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 ALX04_RS16015 ebde50d9d8793fc68c82750aaaa9fe53 233 Gene3D G3DSA:3.40.50.2300 2 124 2.3E-38 T 28-03-2018 ALX04_RS13725 8a8f0b819b8c67ac804c2b74a4419a78 375 ProSitePatterns PS00395 Alanine racemase pyridoxal-phosphate attachment site. 38 48 - T 28-03-2018 IPR020622 Alanine racemase, pyridoxal-phosphate attachment site KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 ALX04_RS13725 8a8f0b819b8c67ac804c2b74a4419a78 375 SUPERFAMILY SSF50621 244 374 4.19E-50 T 28-03-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 ALX04_RS13725 8a8f0b819b8c67ac804c2b74a4419a78 375 Hamap MF_01201 Alanine racemase. 7 374 34.872 T 28-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 ALX04_RS13725 8a8f0b819b8c67ac804c2b74a4419a78 375 Gene3D G3DSA:2.40.37.10 234 375 7.7E-58 T 28-03-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 ALX04_RS13725 8a8f0b819b8c67ac804c2b74a4419a78 375 TIGRFAM TIGR00492 alr: alanine racemase 8 375 9.9E-112 T 28-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 ALX04_RS13725 8a8f0b819b8c67ac804c2b74a4419a78 375 SUPERFAMILY SSF51419 14 250 3.27E-62 T 28-03-2018 IPR029066 PLP-binding barrel ALX04_RS13725 8a8f0b819b8c67ac804c2b74a4419a78 375 Pfam PF00842 Alanine racemase, C-terminal domain 249 373 2.8E-44 T 28-03-2018 IPR011079 Alanine racemase, C-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 ALX04_RS13725 8a8f0b819b8c67ac804c2b74a4419a78 375 SMART SM01005 249 374 2.8E-69 T 28-03-2018 IPR011079 Alanine racemase, C-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 ALX04_RS13725 8a8f0b819b8c67ac804c2b74a4419a78 375 PRINTS PR00992 Alanine racemase signature 168 179 9.3E-71 T 28-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 ALX04_RS13725 8a8f0b819b8c67ac804c2b74a4419a78 375 PRINTS PR00992 Alanine racemase signature 132 144 9.3E-71 T 28-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 ALX04_RS13725 8a8f0b819b8c67ac804c2b74a4419a78 375 PRINTS PR00992 Alanine racemase signature 69 87 9.3E-71 T 28-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 ALX04_RS13725 8a8f0b819b8c67ac804c2b74a4419a78 375 PRINTS PR00992 Alanine racemase signature 356 369 9.3E-71 T 28-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 ALX04_RS13725 8a8f0b819b8c67ac804c2b74a4419a78 375 PRINTS PR00992 Alanine racemase signature 208 235 9.3E-71 T 28-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 ALX04_RS13725 8a8f0b819b8c67ac804c2b74a4419a78 375 PRINTS PR00992 Alanine racemase signature 33 49 9.3E-71 T 28-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 ALX04_RS13725 8a8f0b819b8c67ac804c2b74a4419a78 375 PRINTS PR00992 Alanine racemase signature 265 280 9.3E-71 T 28-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 ALX04_RS13725 8a8f0b819b8c67ac804c2b74a4419a78 375 PRINTS PR00992 Alanine racemase signature 282 297 9.3E-71 T 28-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 ALX04_RS13725 8a8f0b819b8c67ac804c2b74a4419a78 375 PRINTS PR00992 Alanine racemase signature 302 319 9.3E-71 T 28-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 ALX04_RS13725 8a8f0b819b8c67ac804c2b74a4419a78 375 Pfam PF01168 Alanine racemase, N-terminal domain 14 235 7.2E-65 T 28-03-2018 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 ALX04_RS13725 8a8f0b819b8c67ac804c2b74a4419a78 375 Gene3D G3DSA:3.20.20.10 1 233 8.5E-44 T 28-03-2018 IPR029066 PLP-binding barrel ALX04_RS04395 8ab21fef369eafccc3ddf26e2fc87c24 298 Gene3D G3DSA:3.20.20.150 1 298 1.2E-50 T 28-03-2018 ALX04_RS04395 8ab21fef369eafccc3ddf26e2fc87c24 298 SMART SM00518 3 285 6.3E-108 T 28-03-2018 IPR001719 AP endonuclease 2 GO:0003677|GO:0006281|GO:0008270 ALX04_RS04395 8ab21fef369eafccc3ddf26e2fc87c24 298 SUPERFAMILY SSF51658 2 294 1.19E-93 T 28-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain ALX04_RS04395 8ab21fef369eafccc3ddf26e2fc87c24 298 Pfam PF01261 Xylose isomerase-like TIM barrel 22 237 3.4E-36 T 28-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain ALX04_RS04395 8ab21fef369eafccc3ddf26e2fc87c24 298 ProSitePatterns PS00729 AP endonucleases family 2 signature 1. 69 77 - T 28-03-2018 IPR018246 AP endonuclease 2, zinc binding site GO:0008270 ALX04_RS04395 8ab21fef369eafccc3ddf26e2fc87c24 298 ProSitePatterns PS00730 AP endonucleases family 2 signature 2. 175 182 - T 28-03-2018 IPR018246 AP endonuclease 2, zinc binding site GO:0008270 ALX04_RS04395 8ab21fef369eafccc3ddf26e2fc87c24 298 TIGRFAM TIGR00587 nfo: apurinic endonuclease (APN1) 4 282 7.5E-91 T 28-03-2018 IPR001719 AP endonuclease 2 GO:0003677|GO:0006281|GO:0008270 ALX04_RS04395 8ab21fef369eafccc3ddf26e2fc87c24 298 ProSitePatterns PS00731 AP endonucleases family 2 signature 3. 213 229 - T 28-03-2018 IPR018246 AP endonuclease 2, zinc binding site GO:0008270 ALX04_RS04395 8ab21fef369eafccc3ddf26e2fc87c24 298 Hamap MF_00152 Probable endonuclease 4 [nfo]. 2 285 39.752 T 28-03-2018 IPR001719 AP endonuclease 2 GO:0003677|GO:0006281|GO:0008270 ALX04_RS11700 67511f30da1ece8d54464181067460a9 66 ProSitePatterns PS00352 'Cold-shock' domain signature. 15 33 - T 28-03-2018 IPR019844 Cold-shock conserved site ALX04_RS11700 67511f30da1ece8d54464181067460a9 66 Gene3D G3DSA:2.40.50.140 1 66 1.0E-26 T 28-03-2018 ALX04_RS11700 67511f30da1ece8d54464181067460a9 66 Pfam PF00313 'Cold-shock' DNA-binding domain 3 65 3.2E-30 T 28-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 ALX04_RS11700 67511f30da1ece8d54464181067460a9 66 SUPERFAMILY SSF50249 1 65 1.59E-24 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold ALX04_RS11700 67511f30da1ece8d54464181067460a9 66 PRINTS PR00050 Cold shock protein signature 4 19 2.8E-17 T 28-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 ALX04_RS11700 67511f30da1ece8d54464181067460a9 66 PRINTS PR00050 Cold shock protein signature 24 33 2.8E-17 T 28-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 ALX04_RS11700 67511f30da1ece8d54464181067460a9 66 PRINTS PR00050 Cold shock protein signature 39 57 2.8E-17 T 28-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 ALX04_RS11700 67511f30da1ece8d54464181067460a9 66 PIRSF PIRSF002599 1 66 4.5E-23 T 28-03-2018 IPR012156 Cold shock, CspA GO:0003676 ALX04_RS11700 67511f30da1ece8d54464181067460a9 66 SMART SM00357 3 66 3.2E-28 T 28-03-2018 IPR011129 Cold shock domain GO:0003676 ALX04_RS01120 768c5493f1948890657352213157b9e7 289 Pfam PF00535 Glycosyl transferase family 2 11 177 1.8E-14 T 28-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 ALX04_RS01120 768c5493f1948890657352213157b9e7 289 Gene3D G3DSA:3.90.550.10 6 251 7.9E-29 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases ALX04_RS01120 768c5493f1948890657352213157b9e7 289 SUPERFAMILY SSF53448 4 235 2.91E-30 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases ALX04_RS04735 61f4b3c2d1bb736f429ee0c0995d7cdf 394 TIGRFAM TIGR00350 lytR_cpsA_psr: cell envelope-related function transcriptional attenuator common domain 88 235 2.4E-30 T 28-03-2018 IPR004474 Cell envelope-related transcriptional attenuator domain ALX04_RS04735 61f4b3c2d1bb736f429ee0c0995d7cdf 394 Pfam PF03816 Cell envelope-related transcriptional attenuator domain 88 236 1.4E-36 T 28-03-2018 IPR004474 Cell envelope-related transcriptional attenuator domain ALX04_RS05070 dc96826f972e46e255c759b806ecfce8 116 Pfam PF06305 Lipopolysaccharide assembly protein A domain 24 89 1.0E-12 T 28-03-2018 IPR010445 Lipopolysaccharide assembly protein A domain GO:0005887 ALX04_RS05070 dc96826f972e46e255c759b806ecfce8 116 Gene3D G3DSA:1.10.287.70 1 111 7.5E-4 T 28-03-2018 ALX04_RS07740 c94955e229773521924f0b57195f5370 494 SUPERFAMILY SSF55347 183 493 1.77E-107 T 28-03-2018 ALX04_RS07740 c94955e229773521924f0b57195f5370 494 PIRSF PIRSF000110 1 494 2.9E-184 T 28-03-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 ALX04_RS07740 c94955e229773521924f0b57195f5370 494 TIGRFAM TIGR00871 zwf: glucose-6-phosphate dehydrogenase 8 490 3.1E-179 T 28-03-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 ALX04_RS07740 c94955e229773521924f0b57195f5370 494 SUPERFAMILY SSF51735 7 191 1.28E-63 T 28-03-2018 IPR016040 NAD(P)-binding domain ALX04_RS07740 c94955e229773521924f0b57195f5370 494 ProSitePatterns PS00069 Glucose-6-phosphate dehydrogenase active site. 178 184 - T 28-03-2018 IPR019796 Glucose-6-phosphate dehydrogenase, active site GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 ALX04_RS07740 c94955e229773521924f0b57195f5370 494 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 144 157 1.2E-45 T 28-03-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 ALX04_RS07740 c94955e229773521924f0b57195f5370 494 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 325 351 1.2E-45 T 28-03-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 ALX04_RS07740 c94955e229773521924f0b57195f5370 494 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 220 237 1.2E-45 T 28-03-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 ALX04_RS07740 c94955e229773521924f0b57195f5370 494 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 168 196 1.2E-45 T 28-03-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 ALX04_RS07740 c94955e229773521924f0b57195f5370 494 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 238 254 1.2E-45 T 28-03-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 ALX04_RS07740 c94955e229773521924f0b57195f5370 494 Gene3D G3DSA:3.30.360.10 190 493 1.2E-115 T 28-03-2018 ALX04_RS07740 c94955e229773521924f0b57195f5370 494 Pfam PF02781 Glucose-6-phosphate dehydrogenase, C-terminal domain 191 490 4.5E-108 T 28-03-2018 IPR022675 Glucose-6-phosphate dehydrogenase, C-terminal GO:0004345|GO:0006006|GO:0050661|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 ALX04_RS07740 c94955e229773521924f0b57195f5370 494 Hamap MF_00966 Glucose-6-phosphate 1-dehydrogenase [zwf]. 6 492 81.281 T 28-03-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 ALX04_RS07740 c94955e229773521924f0b57195f5370 494 Pfam PF00479 Glucose-6-phosphate dehydrogenase, NAD binding domain 11 188 9.4E-64 T 28-03-2018 IPR022674 Glucose-6-phosphate dehydrogenase, NAD-binding GO:0004345|GO:0006006|GO:0050661|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 ALX04_RS07740 c94955e229773521924f0b57195f5370 494 Gene3D G3DSA:3.40.50.720 4 189 1.5E-67 T 28-03-2018 ALX04_RS02760 99249dfed89f6bf190fa12ff9783f20d 209 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 34 203 2.3E-25 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 ALX04_RS02760 99249dfed89f6bf190fa12ff9783f20d 209 Gene3D G3DSA:1.10.3720.10 2 208 2.6E-30 T 28-03-2018 ALX04_RS02760 99249dfed89f6bf190fa12ff9783f20d 209 SUPERFAMILY SSF161098 12 196 2.51E-42 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 ALX04_RS06165 3f42b4f892d243b828c2e55358b388ae 268 Gene3D G3DSA:3.40.50.300 1 247 6.4E-57 T 28-03-2018 ALX04_RS06165 3f42b4f892d243b828c2e55358b388ae 268 SUPERFAMILY SSF52540 1 264 6.35E-57 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase ALX04_RS06165 3f42b4f892d243b828c2e55358b388ae 268 Pfam PF13614 AAA domain 3 162 3.1E-24 T 28-03-2018 IPR025669 AAA domain ALX04_RS06165 3f42b4f892d243b828c2e55358b388ae 268 PIRSF PIRSF003092 1 268 3.4E-85 T 28-03-2018 IPR025501 ATP binding protein MinD ALX04_RS06165 3f42b4f892d243b828c2e55358b388ae 268 TIGRFAM TIGR01968 minD_bact: septum site-determining protein MinD 3 264 7.9E-115 T 28-03-2018 IPR010223 ATP binding protein MinD, bacterial-type GO:0016887 ALX04_RS04640 4ef7439321e296b1b9348c8bd9615457 240 Pfam PF00696 Amino acid kinase family 7 217 4.3E-29 T 28-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase ALX04_RS04640 4ef7439321e296b1b9348c8bd9615457 240 SUPERFAMILY SSF53633 5 238 1.02E-73 T 28-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase ALX04_RS04640 4ef7439321e296b1b9348c8bd9615457 240 PIRSF PIRSF005650 1 240 1.4E-96 T 28-03-2018 IPR011817 Uridylate kinase GO:0006221|GO:0009041 KEGG: 00240+2.7.4.22 ALX04_RS04640 4ef7439321e296b1b9348c8bd9615457 240 Gene3D G3DSA:3.40.1160.10 1 239 1.1E-43 T 28-03-2018 ALX04_RS04640 4ef7439321e296b1b9348c8bd9615457 240 TIGRFAM TIGR02075 pyrH_bact: UMP kinase 6 237 3.1E-100 T 28-03-2018 IPR015963 Uridylate kinase, bacteria GO:0005737|GO:0006221|GO:0033862 KEGG: 00240+2.7.4.22 ALX04_RS04640 4ef7439321e296b1b9348c8bd9615457 240 Hamap MF_01220_B Uridylate kinase [pyrH]. 4 238 44.628 T 28-03-2018 IPR015963 Uridylate kinase, bacteria GO:0005737|GO:0006221|GO:0033862 KEGG: 00240+2.7.4.22 ALX04_RS01135 e88eda6d022d576112e84b81959ead27 237 SUPERFAMILY SSF53448 1 225 7.74E-52 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases ALX04_RS01135 e88eda6d022d576112e84b81959ead27 237 Gene3D G3DSA:3.90.550.10 1 231 2.6E-41 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases ALX04_RS01135 e88eda6d022d576112e84b81959ead27 237 Pfam PF00535 Glycosyl transferase family 2 3 163 2.6E-26 T 28-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 ALX04_RS03570 e0703de98002add951a65d8a3ff9eeb5 253 Pfam PF12730 ABC-2 family transporter protein 7 180 3.5E-10 T 28-03-2018 IPR032688 ABC-2 family transporter protein GO:0006810 ALX04_RS02160 ee35efd9604ade4e9576d90a5fa4d8c0 208 Gene3D G3DSA:1.10.10.60 5 60 5.7E-11 T 28-03-2018 ALX04_RS02160 ee35efd9604ade4e9576d90a5fa4d8c0 208 SUPERFAMILY SSF46689 7 69 2.51E-10 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 ALX04_RS02160 ee35efd9604ade4e9576d90a5fa4d8c0 208 Pfam PF00440 Bacterial regulatory proteins, tetR family 17 59 5.2E-8 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 ALX04_RS02160 ee35efd9604ade4e9576d90a5fa4d8c0 208 SUPERFAMILY SSF48498 83 194 4.3E-6 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal ALX04_RS02160 ee35efd9604ade4e9576d90a5fa4d8c0 208 Gene3D G3DSA:1.10.357.10 61 201 1.1E-7 T 28-03-2018 ALX04_RS03980 8d3a280811c651e5ab56975c2e9844c8 295 Gene3D G3DSA:2.40.50.140 1 59 0.34 T 28-03-2018 ALX04_RS03980 8d3a280811c651e5ab56975c2e9844c8 295 Gene3D G3DSA:1.10.10.10 225 285 2.0E-23 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS03980 8d3a280811c651e5ab56975c2e9844c8 295 Gene3D G3DSA:2.40.50.140 67 224 2.2E-13 T 28-03-2018 ALX04_RS03980 8d3a280811c651e5ab56975c2e9844c8 295 PIRSF PIRSF012524 1 287 3.3E-91 T 28-03-2018 IPR014464 Conserved virulence factor B ALX04_RS03980 8d3a280811c651e5ab56975c2e9844c8 295 Pfam PF13509 S1 domain 5 62 2.9E-15 T 28-03-2018 ALX04_RS09095 c0adb11e90bf73d1bf27314f45d08307 234 SUPERFAMILY SSF52540 2 232 4.33E-60 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase ALX04_RS09095 c0adb11e90bf73d1bf27314f45d08307 234 Pfam PF00005 ABC transporter 18 162 8.2E-33 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 ALX04_RS09095 c0adb11e90bf73d1bf27314f45d08307 234 Gene3D G3DSA:3.40.50.300 1 234 3.6E-55 T 28-03-2018 ALX04_RS09095 c0adb11e90bf73d1bf27314f45d08307 234 SMART SM00382 26 219 2.6E-7 T 28-03-2018 IPR003593 AAA+ ATPase domain ALX04_RS09095 c0adb11e90bf73d1bf27314f45d08307 234 ProSitePatterns PS00211 ABC transporters family signature. 135 149 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 ALX04_RS09095 c0adb11e90bf73d1bf27314f45d08307 234 PIRSF PIRSF039137 1 234 2.0E-107 T 28-03-2018 IPR030660 High-affinity branched-chain amino acid transport ATP-binding protein GO:0015658|GO:0015803 ALX04_RS03565 2c079829317f07644a8d443093158fb8 299 SMART SM00382 30 207 1.2E-11 T 28-03-2018 IPR003593 AAA+ ATPase domain ALX04_RS03565 2c079829317f07644a8d443093158fb8 299 Gene3D G3DSA:3.40.50.300 2 251 1.3E-53 T 28-03-2018 ALX04_RS03565 2c079829317f07644a8d443093158fb8 299 ProSitePatterns PS00211 ABC transporters family signature. 131 145 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 ALX04_RS03565 2c079829317f07644a8d443093158fb8 299 Pfam PF00005 ABC transporter 21 159 4.2E-26 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 ALX04_RS03565 2c079829317f07644a8d443093158fb8 299 SUPERFAMILY SSF52540 3 225 5.72E-53 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase ALX04_RS14460 d7be445ddb9e0c13c628670fa6d97b95 151 TIGRFAM TIGR01575 rimI: ribosomal-protein-alanine acetyltransferase 19 146 1.8E-35 T 28-03-2018 IPR006464 N-acetyltransferase RimI/Ard1 GO:0006474|GO:0016407 ALX04_RS14460 d7be445ddb9e0c13c628670fa6d97b95 151 SUPERFAMILY SSF55729 19 150 1.03E-26 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase ALX04_RS14460 d7be445ddb9e0c13c628670fa6d97b95 151 Gene3D G3DSA:3.40.630.30 8 150 8.0E-26 T 28-03-2018 ALX04_RS14460 d7be445ddb9e0c13c628670fa6d97b95 151 Pfam PF00583 Acetyltransferase (GNAT) family 38 126 1.1E-13 T 28-03-2018 IPR000182 GNAT domain GO:0008080 ALX04_RS13185 6610483c7c43974ae8f0c1c5c1377802 323 ProSitePatterns PS00211 ABC transporters family signature. 139 153 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 ALX04_RS13185 6610483c7c43974ae8f0c1c5c1377802 323 Pfam PF00005 ABC transporter 22 166 1.8E-31 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 ALX04_RS13185 6610483c7c43974ae8f0c1c5c1377802 323 SUPERFAMILY SSF52540 5 242 1.31E-71 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase ALX04_RS13185 6610483c7c43974ae8f0c1c5c1377802 323 Gene3D G3DSA:3.40.50.300 1 249 4.2E-73 T 28-03-2018 ALX04_RS13185 6610483c7c43974ae8f0c1c5c1377802 323 SMART SM00382 29 216 6.3E-12 T 28-03-2018 IPR003593 AAA+ ATPase domain ALX04_RS13185 6610483c7c43974ae8f0c1c5c1377802 323 Gene3D G3DSA:3.10.580.10 265 323 0.0018 T 28-03-2018 ALX04_RS13710 994ee3a0523f1836d5083f44eef11d58 528 Gene3D G3DSA:3.40.50.300 221 526 2.6E-48 T 28-03-2018 ALX04_RS13710 994ee3a0523f1836d5083f44eef11d58 528 ProSitePatterns PS00039 DEAD-box subfamily ATP-dependent helicases signature. 148 156 - T 28-03-2018 IPR000629 ATP-dependent RNA helicase DEAD-box, conserved site ALX04_RS13710 994ee3a0523f1836d5083f44eef11d58 528 SMART SM00490 253 334 2.9E-36 T 28-03-2018 IPR001650 Helicase, C-terminal ALX04_RS13710 994ee3a0523f1836d5083f44eef11d58 528 Gene3D G3DSA:3.40.50.300 1 220 6.2E-63 T 28-03-2018 ALX04_RS13710 994ee3a0523f1836d5083f44eef11d58 528 Hamap MF_01493 DEAD-box ATP-dependent RNA helicase CshA [cshA]. 1 525 46.81 T 28-03-2018 IPR030880 DEAD-box ATP-dependent RNA helicase CshA GO:0004004|GO:0005524|GO:0010501 ALX04_RS13710 994ee3a0523f1836d5083f44eef11d58 528 SMART SM00487 20 217 1.6E-66 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain ALX04_RS13710 994ee3a0523f1836d5083f44eef11d58 528 Pfam PF00271 Helicase conserved C-terminal domain 226 334 1.2E-31 T 28-03-2018 IPR001650 Helicase, C-terminal ALX04_RS13710 994ee3a0523f1836d5083f44eef11d58 528 SUPERFAMILY SSF52540 69 355 2.19E-76 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase ALX04_RS13710 994ee3a0523f1836d5083f44eef11d58 528 Pfam PF00270 DEAD/DEAH box helicase 25 190 1.2E-52 T 28-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 ALX04_RS11175 7663e2aacae0b6dadd91c45d0cf6eef3 487 PRINTS PR00131 Glycosyl hydrolase family 1 signature 316 330 1.1E-16 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 ALX04_RS11175 7663e2aacae0b6dadd91c45d0cf6eef3 487 PRINTS PR00131 Glycosyl hydrolase family 1 signature 423 440 1.1E-16 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 ALX04_RS11175 7663e2aacae0b6dadd91c45d0cf6eef3 487 PRINTS PR00131 Glycosyl hydrolase family 1 signature 448 460 1.1E-16 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 ALX04_RS11175 7663e2aacae0b6dadd91c45d0cf6eef3 487 PRINTS PR00131 Glycosyl hydrolase family 1 signature 381 389 1.1E-16 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 ALX04_RS11175 7663e2aacae0b6dadd91c45d0cf6eef3 487 PRINTS PR00131 Glycosyl hydrolase family 1 signature 402 413 1.1E-16 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 ALX04_RS11175 7663e2aacae0b6dadd91c45d0cf6eef3 487 SUPERFAMILY SSF51445 8 484 2.3E-159 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily ALX04_RS11175 7663e2aacae0b6dadd91c45d0cf6eef3 487 ProSitePatterns PS00653 Glycosyl hydrolases family 1 N-terminal signature. 14 28 - T 28-03-2018 IPR033132 Glycosyl hydrolases family 1, N-terminal conserved site ALX04_RS11175 7663e2aacae0b6dadd91c45d0cf6eef3 487 Gene3D G3DSA:3.20.20.80 2 487 1.0E-149 T 28-03-2018 ALX04_RS11175 7663e2aacae0b6dadd91c45d0cf6eef3 487 Pfam PF00232 Glycosyl hydrolase family 1 9 483 2.1E-131 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 ALX04_RS11175 7663e2aacae0b6dadd91c45d0cf6eef3 487 ProSitePatterns PS00572 Glycosyl hydrolases family 1 active site. 381 389 - T 28-03-2018 IPR018120 Glycoside hydrolase family 1, active site ALX04_RS12060 68ce4c517b10ae4504e7d4995a261977 530 Pfam PF08797 HIRAN domain 69 142 3.2E-10 T 28-03-2018 IPR014905 HIRAN domain GO:0003676|GO:0008270|GO:0016818 Reactome: R-HSA-8866654 ALX04_RS12060 68ce4c517b10ae4504e7d4995a261977 530 SMART SM00910 64 164 9.9E-22 T 28-03-2018 IPR014905 HIRAN domain GO:0003676|GO:0008270|GO:0016818 Reactome: R-HSA-8866654 ALX04_RS10700 04e8114c003228ca297925aa8e7b686c 190 SUPERFAMILY SSF46689 11 71 7.7E-7 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 ALX04_RS10700 04e8114c003228ca297925aa8e7b686c 190 Gene3D G3DSA:1.10.10.60 5 50 1.7E-5 T 28-03-2018 ALX04_RS10700 04e8114c003228ca297925aa8e7b686c 190 SUPERFAMILY SSF48498 92 185 1.78E-9 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal ALX04_RS10700 04e8114c003228ca297925aa8e7b686c 190 Gene3D G3DSA:1.10.357.10 51 187 2.3E-12 T 28-03-2018 ALX04_RS01635 7e091f9149798a693b4dd6e661ce48f7 556 Pfam PF05598 Transposase domain (DUF772) 45 101 2.2E-11 T 28-03-2018 IPR008490 Transposase InsH, N-terminal ALX04_RS01635 7e091f9149798a693b4dd6e661ce48f7 556 Gene3D G3DSA:3.90.350.10 230 491 4.3E-8 T 28-03-2018 IPR014736 Transposase, Tn5-like, core ALX04_RS01635 7e091f9149798a693b4dd6e661ce48f7 556 Pfam PF01609 Transposase DDE domain 257 508 9.2E-33 T 28-03-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 ALX04_RS09015 6c0a76d79459b22a41fcc207a6a6bd2c 307 Gene3D G3DSA:3.20.20.140 1 307 1.0E-54 T 28-03-2018 ALX04_RS09015 6c0a76d79459b22a41fcc207a6a6bd2c 307 SUPERFAMILY SSF51556 3 305 3.35E-76 T 28-03-2018 IPR032466 Metal-dependent hydrolase ALX04_RS09015 6c0a76d79459b22a41fcc207a6a6bd2c 307 Pfam PF04909 Amidohydrolase 4 305 1.8E-33 T 28-03-2018 IPR006680 Amidohydrolase-related GO:0016787 ALX04_RS03385 8b136379b3b6de09df7effe68ae50656 317 SUPERFAMILY SSF52540 4 244 3.93E-78 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase ALX04_RS03385 8b136379b3b6de09df7effe68ae50656 317 SUPERFAMILY SSF50331 246 317 1.19E-5 T 28-03-2018 IPR008995 Molybdate/tungstate binding, C-terminal ALX04_RS03385 8b136379b3b6de09df7effe68ae50656 317 ProSitePatterns PS00211 ABC transporters family signature. 138 152 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 ALX04_RS03385 8b136379b3b6de09df7effe68ae50656 317 SMART SM00382 27 214 4.6E-17 T 28-03-2018 IPR003593 AAA+ ATPase domain ALX04_RS03385 8b136379b3b6de09df7effe68ae50656 317 Gene3D G3DSA:3.40.50.300 1 280 4.3E-74 T 28-03-2018 ALX04_RS03385 8b136379b3b6de09df7effe68ae50656 317 Pfam PF08402 TOBE domain 249 289 9.1E-5 T 28-03-2018 IPR013611 Transport-associated OB, type 2 GO:0005215|GO:0005524|GO:0006810|GO:0016820|GO:0043190 ALX04_RS03385 8b136379b3b6de09df7effe68ae50656 317 Pfam PF00005 ABC transporter 19 165 2.8E-37 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 ALX04_RS07735 376d2a12b213ef9f5bc358c2eca2e5e0 115 Pfam PF13630 SdpI/YhfL protein family 29 96 7.8E-10 T 28-03-2018 IPR025962 SdpI/YhfL protein family ALX04_RS02420 9d2bd57ac2b7ea67d7c8888726636848 118 Pfam PF02410 Ribosomal silencing factor during starvation 11 104 2.9E-28 T 28-03-2018 ALX04_RS02420 9d2bd57ac2b7ea67d7c8888726636848 118 SUPERFAMILY SSF81301 1 115 1.96E-41 T 28-03-2018 ALX04_RS02420 9d2bd57ac2b7ea67d7c8888726636848 118 Hamap MF_01477 Ribosomal silencing factor RsfS [rsfS]. 3 105 26.096 T 28-03-2018 IPR004394 Protein Iojap/ribosomal silencing factor RsfS ALX04_RS02420 9d2bd57ac2b7ea67d7c8888726636848 118 Gene3D G3DSA:3.30.460.10 1 116 2.7E-36 T 28-03-2018 ALX04_RS02420 9d2bd57ac2b7ea67d7c8888726636848 118 TIGRFAM TIGR00090 rsfS_iojap_ybeB: ribosome silencing factor 7 104 4.3E-37 T 28-03-2018 IPR004394 Protein Iojap/ribosomal silencing factor RsfS ALX04_RS09045 75c0aceb0c5ae68e299d3a94e66c9e3e 217 SUPERFAMILY SSF55469 13 206 1.1E-51 T 28-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 ALX04_RS09045 75c0aceb0c5ae68e299d3a94e66c9e3e 217 Pfam PF00881 Nitroreductase family 20 197 3.3E-25 T 28-03-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 ALX04_RS09045 75c0aceb0c5ae68e299d3a94e66c9e3e 217 Gene3D G3DSA:3.40.109.10 2 217 1.6E-38 T 28-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 ALX04_RS13965 c0855e3958c46ad6a89f890e4d1c20df 259 SMART SM00943 10 166 1.6E-47 T 28-03-2018 IPR015330 DNA primase/polymerase, bifunctional, N-terminal ALX04_RS13965 c0855e3958c46ad6a89f890e4d1c20df 259 SUPERFAMILY SSF56747 5 180 5.36E-26 T 28-03-2018 ALX04_RS13965 c0855e3958c46ad6a89f890e4d1c20df 259 Pfam PF08708 Primase C terminal 1 (PriCT-1) 197 259 3.9E-15 T 28-03-2018 IPR014820 Primase, C-terminal 1 ALX04_RS13965 c0855e3958c46ad6a89f890e4d1c20df 259 Pfam PF09250 Bifunctional DNA primase/polymerase, N-terminal 10 165 1.3E-30 T 28-03-2018 IPR015330 DNA primase/polymerase, bifunctional, N-terminal ALX04_RS13965 c0855e3958c46ad6a89f890e4d1c20df 259 SMART SM00942 197 259 9.5E-22 T 28-03-2018 IPR014820 Primase, C-terminal 1 ALX04_RS15030 48e3faa94231b3098ca43b6899660f76 282 Pfam PF06574 FAD synthetase 18 168 1.3E-44 T 28-03-2018 IPR015864 FAD synthetase GO:0003919|GO:0009231 KEGG: 00740+2.7.1.26+2.7.7.2|MetaCyc: PWY-5523|MetaCyc: PWY-6167|MetaCyc: PWY-6168|MetaCyc: PWY-7863 ALX04_RS15030 48e3faa94231b3098ca43b6899660f76 282 Gene3D G3DSA:3.40.50.620 2 188 7.1E-39 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold ALX04_RS15030 48e3faa94231b3098ca43b6899660f76 282 SUPERFAMILY SSF52374 20 179 1.52E-29 T 28-03-2018 ALX04_RS05345 e221aaeff8638a3b7b7a32b836d986c4 370 Pfam PF00676 Dehydrogenase E1 component 52 342 4.7E-91 T 28-03-2018 IPR001017 Dehydrogenase, E1 component GO:0008152|GO:0016624 Reactome: R-HSA-389661 ALX04_RS05345 e221aaeff8638a3b7b7a32b836d986c4 370 TIGRFAM TIGR03181 PDH_E1_alph_x: pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit 23 363 1.3E-140 T 28-03-2018 IPR017596 Pyruvate dehydrogenase E1 component subunit alpha/BCKADH E1-alpha KEGG: 00010+1.2.4.1|KEGG: 00020+1.2.4.1|KEGG: 00620+1.2.4.1 ALX04_RS05345 e221aaeff8638a3b7b7a32b836d986c4 370 Gene3D G3DSA:3.40.50.970 5 364 7.9E-79 T 28-03-2018 ALX04_RS05345 e221aaeff8638a3b7b7a32b836d986c4 370 SUPERFAMILY SSF52518 21 365 3.54E-95 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold ALX04_RS12085 bb37cfcc1adde052e6a1c6b7f52f1ea2 1358 Pfam PF13395 HNH endonuclease 840 888 1.7E-17 T 28-03-2018 IPR003615 HNH nuclease ALX04_RS12085 bb37cfcc1adde052e6a1c6b7f52f1ea2 1358 Pfam PF16592 REC lobe of CRISPR-associated endonuclease Cas9 181 715 1.4E-136 T 28-03-2018 IPR032240 CRISPR-associated endonuclease Cas9, REC lobe ALX04_RS12085 bb37cfcc1adde052e6a1c6b7f52f1ea2 1358 Pfam PF16593 Bridge helix of CRISPR-associated endonuclease Cas9 50 82 2.7E-9 T 28-03-2018 IPR032239 CRISPR-associated endonuclease Cas9, bridge helix ALX04_RS12085 bb37cfcc1adde052e6a1c6b7f52f1ea2 1358 Hamap MF_01480 CRISPR-associated endonuclease Cas9 [cas9]. 3 1351 14.605 T 28-03-2018 IPR028629 CRISPR-associated endonuclease Cas9 GO:0004519 ALX04_RS12085 bb37cfcc1adde052e6a1c6b7f52f1ea2 1358 TIGRFAM TIGR01865 cas_Csn1: CRISPR subtype II RNA-guided endonuclease Cas9 5 1026 2.1E-168 T 28-03-2018 IPR028629 CRISPR-associated endonuclease Cas9 GO:0004519 ALX04_RS12085 bb37cfcc1adde052e6a1c6b7f52f1ea2 1358 Pfam PF16595 PAM-interacting domain of CRISPR-associated endonuclease Cas9 1081 1351 1.5E-34 T 28-03-2018 IPR032237 CRISPR-associated endonuclease Cas9, PAM-interacting domain ALX04_RS04580 a16308e0db3ce77bfcd03f7775f42275 117 ProSitePatterns PS01319 Ribosome-binding factor A signature. 76 97 - T 28-03-2018 IPR020053 Ribosome-binding factor A, conserved site GO:0006364 ALX04_RS04580 a16308e0db3ce77bfcd03f7775f42275 117 Gene3D G3DSA:3.30.300.20 4 117 7.3E-32 T 28-03-2018 IPR015946 K homology domain-like, alpha/beta ALX04_RS04580 a16308e0db3ce77bfcd03f7775f42275 117 TIGRFAM TIGR00082 rbfA: ribosome-binding factor A 1 115 1.1E-32 T 28-03-2018 IPR000238 Ribosome-binding factor A GO:0006364 ALX04_RS04580 a16308e0db3ce77bfcd03f7775f42275 117 ProDom PD007327 FACTOR A RIBOSOME-BINDING PROCESSING RRNA 3D-STRUCTURE RIBOSOMAL-BINDING PRECURSOR A RBFA 9 97 2.0E-35 T 28-03-2018 IPR000238 Ribosome-binding factor A GO:0006364 ALX04_RS04580 a16308e0db3ce77bfcd03f7775f42275 117 SUPERFAMILY SSF89919 1 113 6.02E-31 T 28-03-2018 IPR023799 Ribosome-binding factor A domain ALX04_RS04580 a16308e0db3ce77bfcd03f7775f42275 117 Hamap MF_00003 Ribosome-binding factor A [rbfA]. 2 117 21.81 T 28-03-2018 IPR000238 Ribosome-binding factor A GO:0006364 ALX04_RS04580 a16308e0db3ce77bfcd03f7775f42275 117 Pfam PF02033 Ribosome-binding factor A 6 110 2.1E-29 T 28-03-2018 IPR000238 Ribosome-binding factor A GO:0006364 ALX04_RS05905 dcaf21bd2ec64ff6c863e344df5f2b74 242 Hamap MF_00693 Probable transcriptional regulatory protein YebC [yebC]. 3 240 36.277 T 28-03-2018 IPR002876 Transcriptional regulator TACO1-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 ALX04_RS05905 dcaf21bd2ec64ff6c863e344df5f2b74 242 Gene3D G3DSA:3.30.70.980 82 176 3.6E-30 T 28-03-2018 IPR026564 Transcriptional regulator TACO1-like, domain 3 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 ALX04_RS05905 dcaf21bd2ec64ff6c863e344df5f2b74 242 Gene3D G3DSA:3.30.70.980 177 242 5.5E-11 T 28-03-2018 IPR026564 Transcriptional regulator TACO1-like, domain 3 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 ALX04_RS05905 dcaf21bd2ec64ff6c863e344df5f2b74 242 TIGRFAM TIGR01033 TIGR01033: DNA-binding regulatory protein, YebC/PmpR family 1 237 7.1E-96 T 28-03-2018 IPR002876 Transcriptional regulator TACO1-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 ALX04_RS05905 dcaf21bd2ec64ff6c863e344df5f2b74 242 SUPERFAMILY SSF75625 3 242 1.44E-89 T 28-03-2018 IPR029072 YebC-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 ALX04_RS05905 dcaf21bd2ec64ff6c863e344df5f2b74 242 Pfam PF01709 Transcriptional regulator 5 236 1.4E-94 T 28-03-2018 IPR002876 Transcriptional regulator TACO1-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 ALX04_RS05905 dcaf21bd2ec64ff6c863e344df5f2b74 242 Gene3D G3DSA:1.10.10.200 1 78 4.6E-31 T 28-03-2018 IPR017856 Integrase, N-terminal zinc-binding domain-like ALX04_RS08370 ec55bde6cc1d949188303af2522664a4 326 Gene3D G3DSA:3.90.245.10 1 310 1.5E-95 T 28-03-2018 IPR001910 Inosine/uridine-preferring nucleoside hydrolase domain ALX04_RS08370 ec55bde6cc1d949188303af2522664a4 326 Pfam PF01156 Inosine-uridine preferring nucleoside hydrolase 5 302 2.2E-84 T 28-03-2018 IPR001910 Inosine/uridine-preferring nucleoside hydrolase domain ALX04_RS08370 ec55bde6cc1d949188303af2522664a4 326 SUPERFAMILY SSF53590 5 308 1.44E-92 T 28-03-2018 IPR001910 Inosine/uridine-preferring nucleoside hydrolase domain ALX04_RS12895 5559a30ed16981f410a6d2675338ad94 267 SUPERFAMILY SSF53955 196 266 1.36E-8 T 28-03-2018 IPR023346 Lysozyme-like domain ALX04_RS12895 5559a30ed16981f410a6d2675338ad94 267 Pfam PF01476 LysM domain 29 70 1.0E-12 T 28-03-2018 IPR018392 LysM domain ALX04_RS12895 5559a30ed16981f410a6d2675338ad94 267 SMART SM00257 28 72 2.0E-14 T 28-03-2018 IPR018392 LysM domain ALX04_RS12895 5559a30ed16981f410a6d2675338ad94 267 Gene3D G3DSA:1.10.530.10 162 267 2.4E-9 T 28-03-2018 ALX04_RS12895 5559a30ed16981f410a6d2675338ad94 267 SUPERFAMILY SSF54106 28 71 1.44E-9 T 28-03-2018 IPR018392 LysM domain ALX04_RS12895 5559a30ed16981f410a6d2675338ad94 267 Gene3D G3DSA:3.10.350.10 23 77 2.6E-14 T 28-03-2018 ALX04_RS05945 1f679d7717a23bf44fa5834e79885289 297 SUPERFAMILY SSF82689 195 292 1.57E-8 T 28-03-2018 IPR011066 Mechanosensitive ion channel MscS, C-terminal GO:0016020 ALX04_RS05945 1f679d7717a23bf44fa5834e79885289 297 SUPERFAMILY SSF82861 40 129 5.1E-13 T 28-03-2018 IPR011014 Mechanosensitive ion channel MscS, transmembrane-2 GO:0016020 ALX04_RS05945 1f679d7717a23bf44fa5834e79885289 297 Gene3D G3DSA:3.30.70.100 195 290 4.9E-10 T 28-03-2018 ALX04_RS05945 1f679d7717a23bf44fa5834e79885289 297 SUPERFAMILY SSF50182 131 187 2.68E-13 T 28-03-2018 IPR010920 LSM domain ALX04_RS05945 1f679d7717a23bf44fa5834e79885289 297 Pfam PF00924 Mechanosensitive ion channel 88 284 3.5E-40 T 28-03-2018 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 ALX04_RS05945 1f679d7717a23bf44fa5834e79885289 297 Gene3D G3DSA:2.30.30.60 146 194 1.4E-11 T 28-03-2018 ALX04_RS12515 54f1d8fea3ba0e944fbe1713520b5323 276 Pfam PF00248 Aldo/keto reductase family 14 258 9.0E-42 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain ALX04_RS12515 54f1d8fea3ba0e944fbe1713520b5323 276 ProSitePatterns PS00798 Aldo/keto reductase family signature 1. 38 55 - T 28-03-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 ALX04_RS12515 54f1d8fea3ba0e944fbe1713520b5323 276 ProSitePatterns PS00062 Aldo/keto reductase family signature 2. 122 139 - T 28-03-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 ALX04_RS12515 54f1d8fea3ba0e944fbe1713520b5323 276 PIRSF PIRSF000097 1 276 1.7E-69 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 ALX04_RS12515 54f1d8fea3ba0e944fbe1713520b5323 276 ProSitePatterns PS00063 Aldo/keto reductase family putative active site signature. 227 242 - T 28-03-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 ALX04_RS12515 54f1d8fea3ba0e944fbe1713520b5323 276 PRINTS PR00069 Aldo-keto reductase signature 90 108 1.0E-40 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 ALX04_RS12515 54f1d8fea3ba0e944fbe1713520b5323 276 PRINTS PR00069 Aldo-keto reductase signature 122 139 1.0E-40 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 ALX04_RS12515 54f1d8fea3ba0e944fbe1713520b5323 276 PRINTS PR00069 Aldo-keto reductase signature 194 218 1.0E-40 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 ALX04_RS12515 54f1d8fea3ba0e944fbe1713520b5323 276 PRINTS PR00069 Aldo-keto reductase signature 34 58 1.0E-40 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 ALX04_RS12515 54f1d8fea3ba0e944fbe1713520b5323 276 PRINTS PR00069 Aldo-keto reductase signature 156 185 1.0E-40 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 ALX04_RS12515 54f1d8fea3ba0e944fbe1713520b5323 276 SUPERFAMILY SSF51430 3 259 8.51E-81 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain ALX04_RS12515 54f1d8fea3ba0e944fbe1713520b5323 276 Gene3D G3DSA:3.20.20.100 1 273 8.5E-82 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain ALX04_RS14755 0fa7f2addbbcbd67b4c582385e083edc 400 PIRSF PIRSF000724 2 400 9.1E-139 T 28-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 ALX04_RS14755 0fa7f2addbbcbd67b4c582385e083edc 400 Pfam PF00162 Phosphoglycerate kinase 6 389 7.2E-154 T 28-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 ALX04_RS14755 0fa7f2addbbcbd67b4c582385e083edc 400 PRINTS PR00477 Phosphoglycerate kinase family signature 146 168 2.4E-90 T 28-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 ALX04_RS14755 0fa7f2addbbcbd67b4c582385e083edc 400 PRINTS PR00477 Phosphoglycerate kinase family signature 352 363 2.4E-90 T 28-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 ALX04_RS14755 0fa7f2addbbcbd67b4c582385e083edc 400 PRINTS PR00477 Phosphoglycerate kinase family signature 177 199 2.4E-90 T 28-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 ALX04_RS14755 0fa7f2addbbcbd67b4c582385e083edc 400 PRINTS PR00477 Phosphoglycerate kinase family signature 31 53 2.4E-90 T 28-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 ALX04_RS14755 0fa7f2addbbcbd67b4c582385e083edc 400 PRINTS PR00477 Phosphoglycerate kinase family signature 110 125 2.4E-90 T 28-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 ALX04_RS14755 0fa7f2addbbcbd67b4c582385e083edc 400 PRINTS PR00477 Phosphoglycerate kinase family signature 200 219 2.4E-90 T 28-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 ALX04_RS14755 0fa7f2addbbcbd67b4c582385e083edc 400 PRINTS PR00477 Phosphoglycerate kinase family signature 318 343 2.4E-90 T 28-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 ALX04_RS14755 0fa7f2addbbcbd67b4c582385e083edc 400 PRINTS PR00477 Phosphoglycerate kinase family signature 10 26 2.4E-90 T 28-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 ALX04_RS14755 0fa7f2addbbcbd67b4c582385e083edc 400 PRINTS PR00477 Phosphoglycerate kinase family signature 375 392 2.4E-90 T 28-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 ALX04_RS14755 0fa7f2addbbcbd67b4c582385e083edc 400 Gene3D G3DSA:3.40.50.1260 4 188 1.0E-67 T 28-03-2018 IPR015824 Phosphoglycerate kinase, N-terminal GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 ALX04_RS14755 0fa7f2addbbcbd67b4c582385e083edc 400 SUPERFAMILY SSF53748 3 399 3.77E-149 T 28-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 ALX04_RS14755 0fa7f2addbbcbd67b4c582385e083edc 400 Gene3D G3DSA:3.40.50.1260 189 387 2.3E-80 T 28-03-2018 IPR015824 Phosphoglycerate kinase, N-terminal GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 ALX04_RS14755 0fa7f2addbbcbd67b4c582385e083edc 400 Hamap MF_00145 Phosphoglycerate kinase [pgk]. 8 399 40.988 T 28-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 ALX04_RS14755 0fa7f2addbbcbd67b4c582385e083edc 400 ProSitePatterns PS00111 Phosphoglycerate kinase signature. 15 25 - T 28-03-2018 IPR015911 Phosphoglycerate kinase, conserved site GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 ALX04_RS05865 1ed71e08a15921e395cbae3fd2f0d7d2 336 Gene3D G3DSA:3.40.50.150 96 334 4.6E-30 T 28-03-2018 ALX04_RS05865 1ed71e08a15921e395cbae3fd2f0d7d2 336 Pfam PF02384 N-6 DNA Methylase 110 311 1.7E-12 T 28-03-2018 IPR003356 DNA methylase, adenine-specific GO:0003677|GO:0006306|GO:0008170 ALX04_RS05865 1ed71e08a15921e395cbae3fd2f0d7d2 336 PIRSF PIRSF026567 1 335 5.3E-138 T 28-03-2018 IPR016843 S-adenosyl-L-methionine dependent adenine methyltransferase, bacteria, predicted ALX04_RS05865 1ed71e08a15921e395cbae3fd2f0d7d2 336 SUPERFAMILY SSF53335 25 314 1.72E-42 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase ALX04_RS15870 21ffa2185dd0033b579b06b0c9507ab2 279 Gene3D G3DSA:1.10.3720.10 46 279 1.2E-32 T 28-03-2018 ALX04_RS15870 21ffa2185dd0033b579b06b0c9507ab2 279 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 110 273 5.9E-25 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 ALX04_RS15870 21ffa2185dd0033b579b06b0c9507ab2 279 SUPERFAMILY SSF161098 87 271 1.96E-38 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 ALX04_RS10710 49dd52affe33f60b5e296aff60423778 322 Pfam PF06207 Protein of unknown function (DUF1002) 42 277 1.5E-57 T 28-03-2018 IPR009343 Protein of unknown function DUF1002 ALX04_RS11220 816c4f30d008e05e4e99da8d93a3cf89 271 Gene3D G3DSA:3.40.50.1000 1 271 1.1E-44 T 28-03-2018 IPR023214 HAD-like domain ALX04_RS11220 816c4f30d008e05e4e99da8d93a3cf89 271 Pfam PF08282 haloacid dehalogenase-like hydrolase 7 266 2.7E-64 T 28-03-2018 IPR023214 HAD-like domain ALX04_RS11220 816c4f30d008e05e4e99da8d93a3cf89 271 TIGRFAM TIGR00099 Cof-subfamily: Cof-like hydrolase 6 266 6.9E-63 T 28-03-2018 IPR000150 Cof family GO:0016787 ALX04_RS11220 816c4f30d008e05e4e99da8d93a3cf89 271 SUPERFAMILY SSF56784 1 269 8.28E-73 T 28-03-2018 IPR023214 HAD-like domain ALX04_RS11220 816c4f30d008e05e4e99da8d93a3cf89 271 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 6 239 8.6E-27 T 28-03-2018 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 ALX04_RS12550 da0d13edd4119a50a3a19be375986c3c 306 Gene3D G3DSA:2.60.120.10 34 254 9.1E-9 T 28-03-2018 IPR014710 RmlC-like jelly roll fold ALX04_RS12550 da0d13edd4119a50a3a19be375986c3c 306 Pfam PF12833 Helix-turn-helix domain 217 292 1.4E-16 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 ALX04_RS12550 da0d13edd4119a50a3a19be375986c3c 306 SMART SM00342 208 291 1.9E-17 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 ALX04_RS12550 da0d13edd4119a50a3a19be375986c3c 306 Gene3D G3DSA:1.10.10.60 255 306 2.0E-12 T 28-03-2018 ALX04_RS12550 da0d13edd4119a50a3a19be375986c3c 306 SUPERFAMILY SSF46689 244 297 1.43E-12 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 ALX04_RS12550 da0d13edd4119a50a3a19be375986c3c 306 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 245 287 - T 28-03-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 ALX04_RS12550 da0d13edd4119a50a3a19be375986c3c 306 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 260 275 2.5E-5 T 28-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 ALX04_RS12550 da0d13edd4119a50a3a19be375986c3c 306 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 275 291 2.5E-5 T 28-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 ALX04_RS14840 096b7cc765081dd91bad222a3a3606b2 153 TIGRFAM TIGR00150 T6A_YjeE: tRNA threonylcarbamoyl adenosine modification protein YjeE 10 136 6.2E-40 T 28-03-2018 IPR003442 tRNA threonylcarbamoyl adenosine modification protein TsaE GO:0002949 ALX04_RS14840 096b7cc765081dd91bad222a3a3606b2 153 SUPERFAMILY SSF52540 23 124 5.58E-22 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase ALX04_RS14840 096b7cc765081dd91bad222a3a3606b2 153 Pfam PF02367 Threonylcarbamoyl adenosine biosynthesis protein TsaE 7 127 1.7E-38 T 28-03-2018 IPR003442 tRNA threonylcarbamoyl adenosine modification protein TsaE GO:0002949 ALX04_RS14840 096b7cc765081dd91bad222a3a3606b2 153 Gene3D G3DSA:3.40.50.300 1 153 2.5E-51 T 28-03-2018 ALX04_RS03375 83e48a78d1cd6f25a2d5dc902c9907e1 553 SUPERFAMILY SSF161098 290 542 1.68E-31 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 ALX04_RS03375 83e48a78d1cd6f25a2d5dc902c9907e1 553 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 367 544 1.9E-10 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 ALX04_RS03375 83e48a78d1cd6f25a2d5dc902c9907e1 553 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 75 259 1.6E-9 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 ALX04_RS03375 83e48a78d1cd6f25a2d5dc902c9907e1 553 SUPERFAMILY SSF161098 6 266 1.87E-37 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 ALX04_RS03375 83e48a78d1cd6f25a2d5dc902c9907e1 553 Gene3D G3DSA:1.10.3720.10 286 552 7.3E-28 T 28-03-2018 ALX04_RS03375 83e48a78d1cd6f25a2d5dc902c9907e1 553 Gene3D G3DSA:1.10.3720.10 44 269 5.9E-24 T 28-03-2018 ALX04_RS12155 002a42bf05edeb529cadadcb959a1d8d 397 Pfam PF07690 Major Facilitator Superfamily 12 347 1.4E-27 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 ALX04_RS12155 002a42bf05edeb529cadadcb959a1d8d 397 SUPERFAMILY SSF103473 7 385 1.7E-43 T 28-03-2018 IPR020846 Major facilitator superfamily domain ALX04_RS12155 002a42bf05edeb529cadadcb959a1d8d 397 Gene3D G3DSA:1.20.1250.20 2 195 5.7E-19 T 28-03-2018 ALX04_RS12155 002a42bf05edeb529cadadcb959a1d8d 397 Gene3D G3DSA:1.20.1250.20 199 392 4.0E-16 T 28-03-2018 ALX04_RS00625 078c80e52aece98e95116839b17dd3b2 203 Pfam PF05683 Fumarase C-terminus 9 179 6.9E-39 T 28-03-2018 IPR004647 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain GO:0016836 ALX04_RS00625 078c80e52aece98e95116839b17dd3b2 203 TIGRFAM TIGR00723 ttdB_fumA_fumB: hydrolyase, tartrate beta subunit/fumarate domain protein, Fe-S type 14 178 1.3E-61 T 28-03-2018 IPR004647 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain GO:0016836 ALX04_RS00625 078c80e52aece98e95116839b17dd3b2 203 SUPERFAMILY SSF117457 4 178 7.19E-54 T 28-03-2018 IPR004647 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain GO:0016836 ALX04_RS00625 078c80e52aece98e95116839b17dd3b2 203 Gene3D G3DSA:3.20.130.10 2 178 2.6E-59 T 28-03-2018 IPR004647 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain GO:0016836 ALX04_RS01100 949c29db374df7f80ada65ad366e48b7 256 Pfam PF02706 Chain length determinant protein 12 93 2.5E-10 T 28-03-2018 IPR003856 Polysaccharide chain length determinant N-terminal domain GO:0009103|GO:0016020 ALX04_RS01100 949c29db374df7f80ada65ad366e48b7 256 Gene3D G3DSA:3.30.1890.10 38 154 7.4E-6 T 28-03-2018 ALX04_RS01100 949c29db374df7f80ada65ad366e48b7 256 Pfam PF13807 G-rich domain on putative tyrosine kinase 146 198 2.7E-10 T 28-03-2018 IPR032807 Tyrosine kinase, G-rich domain ALX04_RS04110 366c07e6b0b89de99d2eb2e688d6c624 250 SMART SM01134 73 233 1.4E-41 T 28-03-2018 ALX04_RS04110 366c07e6b0b89de99d2eb2e688d6c624 250 Pfam PF08220 DeoR-like helix-turn-helix domain 6 59 1.3E-12 T 28-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 ALX04_RS04110 366c07e6b0b89de99d2eb2e688d6c624 250 Gene3D G3DSA:3.40.50.1360 74 239 1.4E-21 T 28-03-2018 ALX04_RS04110 366c07e6b0b89de99d2eb2e688d6c624 250 SUPERFAMILY SSF46785 4 75 2.14E-9 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS04110 366c07e6b0b89de99d2eb2e688d6c624 250 Pfam PF00455 DeoR C terminal sensor domain 77 232 1.3E-32 T 28-03-2018 IPR014036 DeoR C-terminal sensor domain ALX04_RS04110 366c07e6b0b89de99d2eb2e688d6c624 250 ProSitePatterns PS00894 DeoR-type HTH domain signature. 6 40 - T 28-03-2018 IPR018356 Transcription regulator, HTH DeoR-type, conserved site GO:0003700|GO:0006355 ALX04_RS04110 366c07e6b0b89de99d2eb2e688d6c624 250 SMART SM00420 6 58 3.5E-10 T 28-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 ALX04_RS04110 366c07e6b0b89de99d2eb2e688d6c624 250 SUPERFAMILY SSF100950 76 233 5.02E-16 T 28-03-2018 ALX04_RS04110 366c07e6b0b89de99d2eb2e688d6c624 250 Gene3D G3DSA:1.10.10.10 1 60 3.5E-8 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS00990 303c52645c46008c311fc260184cfe56 391 Gene3D G3DSA:3.40.710.10 38 389 3.6E-48 T 28-03-2018 ALX04_RS00990 303c52645c46008c311fc260184cfe56 391 Pfam PF00144 Beta-lactamase 78 371 5.7E-36 T 28-03-2018 IPR001466 Beta-lactamase-related ALX04_RS00990 303c52645c46008c311fc260184cfe56 391 SUPERFAMILY SSF56601 75 382 6.34E-60 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like ALX04_RS12645 3360fe10b82926da0f63090a65119b6e 366 TIGRFAM TIGR01437 selA_rel: uncharacterized pyridoxal phosphate-dependent enzyme 3 359 4.9E-170 T 28-03-2018 IPR006337 Pyridoxal phosphate-dependent enzyme, SelA-like KEGG: 00030+4.3.1.29|MetaCyc: PWY-7310 ALX04_RS12645 3360fe10b82926da0f63090a65119b6e 366 Pfam PF03841 L-seryl-tRNA selenium transferase 20 261 5.1E-11 T 28-03-2018 IPR018319 L-seryl-tRNA selenium transferase-like KEGG: 00450+2.9.1.1|KEGG: 00970+2.9.1.1 ALX04_RS12645 3360fe10b82926da0f63090a65119b6e 366 SUPERFAMILY SSF53383 7 360 3.15E-36 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase ALX04_RS12645 3360fe10b82926da0f63090a65119b6e 366 Gene3D G3DSA:3.40.640.10 24 266 9.1E-22 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 ALX04_RS09660 dfbeb3d2663a3295ae9fcb2e2b4388a7 89 Gene3D G3DSA:1.10.10.60 45 89 8.8E-7 T 28-03-2018 ALX04_RS09660 dfbeb3d2663a3295ae9fcb2e2b4388a7 89 Pfam PF08765 Mor transcription activator family 17 82 1.4E-6 T 28-03-2018 IPR014875 Mor transcription activator ALX04_RS09660 dfbeb3d2663a3295ae9fcb2e2b4388a7 89 SUPERFAMILY SSF46689 7 87 7.77E-10 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 ALX04_RS08315 2ca06abaa6bee8c7aa14a8868ad8a79f 167 Gene3D G3DSA:3.30.1330.30 6 128 1.6E-30 T 28-03-2018 IPR029064 50S ribosomal protein L30e-like ALX04_RS08315 2ca06abaa6bee8c7aa14a8868ad8a79f 167 Pfam PF07997 Protein of unknown function (DUF1694) 6 124 5.3E-33 T 28-03-2018 IPR012543 Protein of unknown function DUF1694 ALX04_RS08315 2ca06abaa6bee8c7aa14a8868ad8a79f 167 PIRSF PIRSF034303 3 154 4.6E-60 T 28-03-2018 IPR012543 Protein of unknown function DUF1694 ALX04_RS08315 2ca06abaa6bee8c7aa14a8868ad8a79f 167 SUPERFAMILY SSF160515 6 130 1.02E-32 T 28-03-2018 ALX04_RS00230 d7ea0182c7e02a9da7a04ae7e0bc4400 66 ProSitePatterns PS00352 'Cold-shock' domain signature. 15 33 - T 28-03-2018 IPR019844 Cold-shock conserved site ALX04_RS00230 d7ea0182c7e02a9da7a04ae7e0bc4400 66 PRINTS PR00050 Cold shock protein signature 4 19 2.7E-18 T 28-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 ALX04_RS00230 d7ea0182c7e02a9da7a04ae7e0bc4400 66 PRINTS PR00050 Cold shock protein signature 39 57 2.7E-18 T 28-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 ALX04_RS00230 d7ea0182c7e02a9da7a04ae7e0bc4400 66 PRINTS PR00050 Cold shock protein signature 24 33 2.7E-18 T 28-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 ALX04_RS00230 d7ea0182c7e02a9da7a04ae7e0bc4400 66 PIRSF PIRSF002599 1 66 6.0E-24 T 28-03-2018 IPR012156 Cold shock, CspA GO:0003676 ALX04_RS00230 d7ea0182c7e02a9da7a04ae7e0bc4400 66 SMART SM00357 3 66 6.5E-29 T 28-03-2018 IPR011129 Cold shock domain GO:0003676 ALX04_RS00230 d7ea0182c7e02a9da7a04ae7e0bc4400 66 Gene3D G3DSA:2.40.50.140 1 66 1.5E-29 T 28-03-2018 ALX04_RS00230 d7ea0182c7e02a9da7a04ae7e0bc4400 66 SUPERFAMILY SSF50249 1 64 2.49E-25 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold ALX04_RS00230 d7ea0182c7e02a9da7a04ae7e0bc4400 66 Pfam PF00313 'Cold-shock' DNA-binding domain 3 65 4.1E-31 T 28-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 ALX04_RS06130 9dbbc17d6442d929eb041a6466053bcc 421 Pfam PF05193 Peptidase M16 inactive domain 182 353 6.5E-20 T 28-03-2018 IPR007863 Peptidase M16, C-terminal ALX04_RS06130 9dbbc17d6442d929eb041a6466053bcc 421 Gene3D G3DSA:3.30.830.10 237 420 2.0E-28 T 28-03-2018 ALX04_RS06130 9dbbc17d6442d929eb041a6466053bcc 421 Gene3D G3DSA:3.30.830.10 2 222 3.2E-22 T 28-03-2018 ALX04_RS06130 9dbbc17d6442d929eb041a6466053bcc 421 SUPERFAMILY SSF63411 251 413 6.17E-27 T 28-03-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 ALX04_RS06130 9dbbc17d6442d929eb041a6466053bcc 421 SUPERFAMILY SSF63411 3 219 4.58E-21 T 28-03-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 ALX04_RS06800 ca4c5503562206dcc9cc85a585d67042 120 SMART SM00530 5 61 2.3E-14 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 ALX04_RS06800 ca4c5503562206dcc9cc85a585d67042 120 Pfam PF01381 Helix-turn-helix 6 61 6.2E-17 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 ALX04_RS06800 ca4c5503562206dcc9cc85a585d67042 120 Gene3D G3DSA:1.10.260.40 1 120 5.4E-24 T 28-03-2018 ALX04_RS06800 ca4c5503562206dcc9cc85a585d67042 120 SUPERFAMILY SSF47413 2 66 2.44E-16 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 ALX04_RS09485 a9ffa0c3bce90f68b3b26c5877f6d2d4 208 PIRSF PIRSF031644 1 208 5.2E-91 T 28-03-2018 IPR008319 Uncharacterised conserved protein UCP031644 ALX04_RS09485 a9ffa0c3bce90f68b3b26c5877f6d2d4 208 SUPERFAMILY SSF55136 91 197 8.11E-10 T 28-03-2018 ALX04_RS09485 a9ffa0c3bce90f68b3b26c5877f6d2d4 208 Pfam PF06445 GyrI-like small molecule binding domain 18 204 5.8E-34 T 28-03-2018 IPR029442 GyrI-like small molecule binding domain ALX04_RS09485 a9ffa0c3bce90f68b3b26c5877f6d2d4 208 Gene3D G3DSA:3.20.80.10 1 206 1.1E-65 T 28-03-2018 IPR011256 Regulatory factor, effector binding domain ALX04_RS09705 3cc5ccef945ecea415ebcdb382bd7d55 442 TIGRFAM TIGR03236 dnd_assoc_1: DNA phosphorothioation-dependent restriction protein DptG 98 441 3.5E-46 T 28-03-2018 IPR017645 DNA phosphorothioation-dependent restriction protein DptG ALX04_RS09705 3cc5ccef945ecea415ebcdb382bd7d55 442 Gene3D G3DSA:3.30.190.20 368 433 0.014 T 28-03-2018 ALX04_RS08610 18835776c889278fac1e877ababd32f5 229 SUPERFAMILY SSF52218 66 190 3.77E-16 T 28-03-2018 IPR029039 Flavoprotein-like domain ALX04_RS08610 18835776c889278fac1e877ababd32f5 229 Pfam PF12682 Flavodoxin 67 187 4.6E-16 T 28-03-2018 IPR008254 Flavodoxin/nitric oxide synthase GO:0010181 ALX04_RS08610 18835776c889278fac1e877ababd32f5 229 ProSitePatterns PS00201 Flavodoxin signature. 68 84 - T 28-03-2018 IPR001226 Flavodoxin, conserved site GO:0009055|GO:0010181 ALX04_RS08610 18835776c889278fac1e877ababd32f5 229 Gene3D G3DSA:3.40.50.360 51 228 4.1E-29 T 28-03-2018 IPR029039 Flavoprotein-like domain ALX04_RS10890 97546ebd3a217507eebb799fa3563ad8 716 Gene3D G3DSA:2.60.120.200 51 281 1.1E-25 T 28-03-2018 ALX04_RS10890 97546ebd3a217507eebb799fa3563ad8 716 SUPERFAMILY SSF49899 248 326 3.35E-18 T 28-03-2018 IPR013320 Concanavalin A-like lectin/glucanase domain ALX04_RS10890 97546ebd3a217507eebb799fa3563ad8 716 SUPERFAMILY SSF49899 57 201 3.35E-18 T 28-03-2018 IPR013320 Concanavalin A-like lectin/glucanase domain ALX04_RS00675 2b304cea84b089717cf155e5e1e42254 320 Pfam PF04198 Putative sugar-binding domain 58 310 7.9E-50 T 28-03-2018 IPR007324 Sugar-binding domain, putative GO:0030246 ALX04_RS00675 2b304cea84b089717cf155e5e1e42254 320 Gene3D G3DSA:1.10.10.60 1 54 1.5E-4 T 28-03-2018 ALX04_RS00675 2b304cea84b089717cf155e5e1e42254 320 SUPERFAMILY SSF100950 62 310 1.59E-51 T 28-03-2018 ALX04_RS00675 2b304cea84b089717cf155e5e1e42254 320 Gene3D G3DSA:3.40.50.1360 55 315 1.0E-29 T 28-03-2018 ALX04_RS04420 e85cd1009e9ed9bdb207d495f21734c8 426 SUPERFAMILY SSF52954 332 418 1.08E-22 T 28-03-2018 IPR004154 Anticodon-binding ALX04_RS04420 e85cd1009e9ed9bdb207d495f21734c8 426 SUPERFAMILY SSF55681 3 319 5.17E-97 T 28-03-2018 ALX04_RS04420 e85cd1009e9ed9bdb207d495f21734c8 426 TIGRFAM TIGR00442 hisS: histidine--tRNA ligase 4 412 1.2E-154 T 28-03-2018 IPR015807 Histidine-tRNA ligase GO:0004821|GO:0005524|GO:0006427 KEGG: 00970+6.1.1.21 ALX04_RS04420 e85cd1009e9ed9bdb207d495f21734c8 426 Pfam PF03129 Anticodon binding domain 333 417 1.4E-12 T 28-03-2018 IPR004154 Anticodon-binding ALX04_RS04420 e85cd1009e9ed9bdb207d495f21734c8 426 Hamap MF_00127 Histidine--tRNA ligase [hisS]. 1 426 33.352 T 28-03-2018 IPR015807 Histidine-tRNA ligase GO:0004821|GO:0005524|GO:0006427 KEGG: 00970+6.1.1.21 ALX04_RS04420 e85cd1009e9ed9bdb207d495f21734c8 426 Gene3D G3DSA:3.40.50.800 329 426 2.3E-18 T 28-03-2018 IPR004154 Anticodon-binding ALX04_RS04420 e85cd1009e9ed9bdb207d495f21734c8 426 Gene3D G3DSA:3.30.930.10 1 327 2.8E-75 T 28-03-2018 ALX04_RS04420 e85cd1009e9ed9bdb207d495f21734c8 426 Pfam PF13393 Histidyl-tRNA synthetase 8 315 5.7E-41 T 28-03-2018 ALX04_RS04420 e85cd1009e9ed9bdb207d495f21734c8 426 PIRSF PIRSF001549 1 423 1.2E-119 T 28-03-2018 IPR004516 Histidine-tRNA ligase/ATP phosphoribosyltransferase regulatory subunit GO:0005737 ALX04_RS01040 43b33f8bf5f9625b38d09f818927d43e 230 Gene3D G3DSA:2.160.10.10 111 230 1.6E-33 T 28-03-2018 ALX04_RS01040 43b33f8bf5f9625b38d09f818927d43e 230 SUPERFAMILY SSF51161 67 228 3.87E-36 T 28-03-2018 IPR011004 Trimeric LpxA-like ALX04_RS01040 43b33f8bf5f9625b38d09f818927d43e 230 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 175 209 2.1E-9 T 28-03-2018 IPR001451 Hexapeptide repeat ALX04_RS01040 43b33f8bf5f9625b38d09f818927d43e 230 Gene3D G3DSA:2.160.10.10 2 110 4.9E-6 T 28-03-2018 ALX04_RS15070 b43c9001533210e1470fbbeca509f800 465 PIRSF PIRSF006060 9 465 1.7E-90 T 28-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 ALX04_RS15070 b43c9001533210e1470fbbeca509f800 465 Pfam PF13520 Amino acid permease 27 433 1.7E-58 T 28-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 ALX04_RS14990 b001120fdc3b2e96371bafcaf0da41ea 317 Gene3D G3DSA:3.30.420.40 1 127 2.0E-38 T 28-03-2018 ALX04_RS14990 b001120fdc3b2e96371bafcaf0da41ea 317 SUPERFAMILY SSF53067 4 128 1.04E-32 T 28-03-2018 ALX04_RS14990 b001120fdc3b2e96371bafcaf0da41ea 317 SUPERFAMILY SSF53067 131 306 5.67E-39 T 28-03-2018 ALX04_RS14990 b001120fdc3b2e96371bafcaf0da41ea 317 Pfam PF02541 Ppx/GppA phosphatase family 24 305 4.3E-58 T 28-03-2018 IPR003695 Ppx/GppA phosphatase KEGG: 00230+3.6.1.40 ALX04_RS14990 b001120fdc3b2e96371bafcaf0da41ea 317 Gene3D G3DSA:3.30.420.150 128 312 5.7E-37 T 28-03-2018 ALX04_RS14990 b001120fdc3b2e96371bafcaf0da41ea 317 TIGRFAM TIGR03706 exo_poly_only: exopolyphosphatase 3 305 6.2E-97 T 28-03-2018 IPR022371 Exopolyphosphatase GO:0004309|GO:0006793 ALX04_RS01755 b0daccaa040b32f52f8d627917a878ee 213 SUPERFAMILY SSF51735 1 211 3.26E-21 T 28-03-2018 IPR016040 NAD(P)-binding domain ALX04_RS01755 b0daccaa040b32f52f8d627917a878ee 213 Pfam PF13460 NAD(P)H-binding 8 197 2.7E-17 T 28-03-2018 IPR016040 NAD(P)-binding domain ALX04_RS01755 b0daccaa040b32f52f8d627917a878ee 213 Gene3D G3DSA:3.40.50.720 1 209 2.9E-13 T 28-03-2018 ALX04_RS13665 8a4caec353663687d6dcc00e41760f31 426 TIGRFAM TIGR01072 murA: UDP-N-acetylglucosamine 1-carboxyvinyltransferase 1 416 6.3E-144 T 28-03-2018 IPR005750 UDP-N-acetylglucosamine 1-carboxyvinyltransferase GO:0008760|GO:0019277 KEGG: 00520+2.5.1.7|KEGG: 00550+2.5.1.7|MetaCyc: PWY-6386|MetaCyc: PWY-6387 ALX04_RS13665 8a4caec353663687d6dcc00e41760f31 426 Pfam PF00275 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) 7 408 3.1E-77 T 28-03-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 ALX04_RS13665 8a4caec353663687d6dcc00e41760f31 426 Gene3D G3DSA:3.65.10.10 21 219 4.4E-41 T 28-03-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 ALX04_RS13665 8a4caec353663687d6dcc00e41760f31 426 Hamap MF_00111 UDP-N-acetylglucosamine 1-carboxyvinyltransferase [murA]. 1 418 39.084 T 28-03-2018 IPR005750 UDP-N-acetylglucosamine 1-carboxyvinyltransferase GO:0008760|GO:0019277 KEGG: 00520+2.5.1.7|KEGG: 00550+2.5.1.7|MetaCyc: PWY-6386|MetaCyc: PWY-6387 ALX04_RS13665 8a4caec353663687d6dcc00e41760f31 426 SUPERFAMILY SSF55205 1 418 1.64E-123 T 28-03-2018 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 ALX04_RS13665 8a4caec353663687d6dcc00e41760f31 426 Gene3D G3DSA:3.65.10.10 220 420 4.0E-38 T 28-03-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 ALX04_RS05380 4a82f3f2e2e27957e41a0d5823d4656c 496 Gene3D G3DSA:3.90.1720.10 380 496 4.2E-29 T 28-03-2018 ALX04_RS05380 4a82f3f2e2e27957e41a0d5823d4656c 496 Pfam PF00877 NlpC/P60 family 394 488 3.1E-22 T 28-03-2018 IPR000064 Endopeptidase, NLPC/P60 domain ALX04_RS05380 4a82f3f2e2e27957e41a0d5823d4656c 496 SUPERFAMILY SSF54001 391 492 2.21E-31 T 28-03-2018 ALX04_RS05380 4a82f3f2e2e27957e41a0d5823d4656c 496 SMART SM00257 32 80 1.2E-9 T 28-03-2018 IPR018392 LysM domain ALX04_RS05380 4a82f3f2e2e27957e41a0d5823d4656c 496 SMART SM00257 101 144 7.7E-17 T 28-03-2018 IPR018392 LysM domain ALX04_RS05380 4a82f3f2e2e27957e41a0d5823d4656c 496 SUPERFAMILY SSF54106 101 144 2.22E-11 T 28-03-2018 IPR018392 LysM domain ALX04_RS05380 4a82f3f2e2e27957e41a0d5823d4656c 496 Pfam PF01476 LysM domain 33 79 6.1E-10 T 28-03-2018 IPR018392 LysM domain ALX04_RS05380 4a82f3f2e2e27957e41a0d5823d4656c 496 Pfam PF01476 LysM domain 102 144 1.1E-13 T 28-03-2018 IPR018392 LysM domain ALX04_RS05380 4a82f3f2e2e27957e41a0d5823d4656c 496 Gene3D G3DSA:3.10.350.10 23 94 9.3E-15 T 28-03-2018 ALX04_RS05380 4a82f3f2e2e27957e41a0d5823d4656c 496 Gene3D G3DSA:3.10.350.10 95 162 2.2E-18 T 28-03-2018 ALX04_RS05380 4a82f3f2e2e27957e41a0d5823d4656c 496 SUPERFAMILY SSF54106 32 79 1.27E-7 T 28-03-2018 IPR018392 LysM domain ALX04_RS07395 1e4fdb0aeca41bd87a7ddbc5ac9d3e67 597 SUPERFAMILY SSF51695 342 569 5.23E-47 T 28-03-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 ALX04_RS07395 1e4fdb0aeca41bd87a7ddbc5ac9d3e67 597 Gene3D G3DSA:3.20.20.190 334 587 2.6E-39 T 28-03-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 ALX04_RS07395 1e4fdb0aeca41bd87a7ddbc5ac9d3e67 597 Pfam PF03009 Glycerophosphoryl diester phosphodiesterase family 348 454 4.3E-17 T 28-03-2018 IPR030395 Glycerophosphodiester phosphodiesterase domain GO:0006629|GO:0008081 ALX04_RS07395 1e4fdb0aeca41bd87a7ddbc5ac9d3e67 597 Pfam PF10110 Membrane domain of glycerophosphoryl diester phosphodiesterase 9 307 1.6E-79 T 28-03-2018 IPR018476 Glycerophosphoryl diester phosphodiesterase, membrane domain ALX04_RS00930 ffa3892ac8567198a57750eeb5e1c392 121 Pfam PF16110 Domain of unknown function (DUF4828) 38 116 2.3E-32 T 28-03-2018 IPR032254 Protein of unknown function DUF4828 ALX04_RS06275 3be6c5139ac4a188f56fd738f47ad75b 271 Pfam PF03613 PTS system mannose/fructose/sorbose family IID component 9 269 5.6E-82 T 28-03-2018 IPR004704 Phosphotransferase system, mannose/fructose/sorbose family IID component GO:0009401|GO:0016021 ALX04_RS07965 16e43a0c1e270791129efd9c7ae26a93 269 Pfam PF06028 Alpha/beta hydrolase of unknown function (DUF915) 39 268 3.9E-36 T 28-03-2018 IPR010315 Protein of unknown function DUF915, hydrolase-like ALX04_RS07965 16e43a0c1e270791129efd9c7ae26a93 269 SUPERFAMILY SSF53474 109 230 1.24E-11 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold ALX04_RS07965 16e43a0c1e270791129efd9c7ae26a93 269 SUPERFAMILY SSF53474 38 78 1.24E-11 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold ALX04_RS07965 16e43a0c1e270791129efd9c7ae26a93 269 Gene3D G3DSA:3.40.50.1820 38 269 3.0E-14 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold ALX04_RS03055 b1bcc066592af85a9629b11d2b1dc440 137 SUPERFAMILY SSF54637 2 135 3.4E-28 T 28-03-2018 IPR029069 HotDog domain ALX04_RS03055 b1bcc066592af85a9629b11d2b1dc440 137 Pfam PF07977 FabA-like domain 7 129 9.7E-14 T 28-03-2018 IPR013114 Beta-hydroxydecanoyl thiol ester dehydrase, FabA/FabZ KEGG: 00061+4.2.1.59|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 ALX04_RS03055 b1bcc066592af85a9629b11d2b1dc440 137 Gene3D G3DSA:3.10.129.10 1 137 6.6E-31 T 28-03-2018 ALX04_RS06640 70e2d1f7b15c091b48f07a26b9bb2dd9 171 ProDom PD004193 ACETYLTRANSFERASE ORNITHINE ARGININE BIOSYNTHESIS ARGJ GLUTAMATE N-ACETYLTRANSFERASE TRANSFERASE ACYLTRANSFERASE BIFUNCTIONAL 26 163 9.0E-4 T 28-03-2018 ALX04_RS08500 61cff90151b21c4aed58cf53c40d52c9 144 Pfam PF13411 MerR HTH family regulatory protein 9 74 5.0E-19 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 ALX04_RS08500 61cff90151b21c4aed58cf53c40d52c9 144 SMART SM00422 9 77 2.1E-21 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 ALX04_RS08500 61cff90151b21c4aed58cf53c40d52c9 144 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 21 34 6.0E-8 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 ALX04_RS08500 61cff90151b21c4aed58cf53c40d52c9 144 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 10 21 6.0E-8 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 ALX04_RS08500 61cff90151b21c4aed58cf53c40d52c9 144 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 44 64 6.0E-8 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 ALX04_RS08500 61cff90151b21c4aed58cf53c40d52c9 144 SUPERFAMILY SSF46955 9 121 3.66E-29 T 28-03-2018 IPR009061 Putative DNA-binding domain ALX04_RS08500 61cff90151b21c4aed58cf53c40d52c9 144 ProSitePatterns PS00552 MerR-type HTH domain signature. 12 34 - T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 ALX04_RS08500 61cff90151b21c4aed58cf53c40d52c9 144 Gene3D G3DSA:1.10.1660.10 5 63 1.0E-21 T 28-03-2018 ALX04_RS08500 61cff90151b21c4aed58cf53c40d52c9 144 Gene3D G3DSA:1.10.1660.10 64 143 3.0E-12 T 28-03-2018 ALX04_RS11255 0e3f7e99e4635d5b5a49a1d7b21ad40b 207 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 70 173 6.1E-6 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 ALX04_RS11255 0e3f7e99e4635d5b5a49a1d7b21ad40b 207 Pfam PF13419 Haloacid dehalogenase-like hydrolase 6 178 7.9E-41 T 28-03-2018 IPR023214 HAD-like domain ALX04_RS11255 0e3f7e99e4635d5b5a49a1d7b21ad40b 207 Gene3D G3DSA:3.40.50.1000 1 198 2.4E-23 T 28-03-2018 IPR023214 HAD-like domain ALX04_RS11255 0e3f7e99e4635d5b5a49a1d7b21ad40b 207 SUPERFAMILY SSF56784 1 206 1.58E-39 T 28-03-2018 IPR023214 HAD-like domain ALX04_RS15785 8498a89cdbbf4bf4cf6def80e02287ff 227 SUPERFAMILY SSF53098 71 185 3.29E-5 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 ALX04_RS15785 8498a89cdbbf4bf4cf6def80e02287ff 227 Pfam PF13610 DDE domain 71 205 1.0E-41 T 28-03-2018 IPR032874 DDE domain ALX04_RS15785 8498a89cdbbf4bf4cf6def80e02287ff 227 Gene3D G3DSA:1.10.10.10 4 56 0.0018 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS15785 8498a89cdbbf4bf4cf6def80e02287ff 227 Gene3D G3DSA:3.30.420.10 59 226 5.1E-12 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 ALX04_RS10585 0bf17bc8f012a2887fcc97d7f9c14963 142 Pfam PF03965 Penicillinase repressor 9 122 6.3E-34 T 28-03-2018 IPR005650 BlaI transcriptional regulatory family GO:0003677|GO:0045892 ALX04_RS10585 0bf17bc8f012a2887fcc97d7f9c14963 142 TIGRFAM TIGR02698 CopY_TcrY: copper transport repressor, CopY/TcrY family 8 137 1.6E-50 T 28-03-2018 IPR014071 Copper transport repressor CopY/TcrY ALX04_RS10585 0bf17bc8f012a2887fcc97d7f9c14963 142 PIRSF PIRSF019455 2 134 1.0E-42 T 28-03-2018 IPR005650 BlaI transcriptional regulatory family GO:0003677|GO:0045892 ALX04_RS10585 0bf17bc8f012a2887fcc97d7f9c14963 142 SUPERFAMILY SSF46785 7 125 9.92E-28 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS10585 0bf17bc8f012a2887fcc97d7f9c14963 142 Gene3D G3DSA:1.10.10.10 10 72 6.0E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS11865 1ec50d9403c577bc8b8879bffe541c0f 222 Pfam PF00117 Glutamine amidotransferase class-I 43 170 1.3E-14 T 28-03-2018 IPR017926 Glutamine amidotransferase ALX04_RS11865 1ec50d9403c577bc8b8879bffe541c0f 222 SUPERFAMILY SSF52317 2 185 1.07E-42 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like ALX04_RS11865 1ec50d9403c577bc8b8879bffe541c0f 222 Gene3D G3DSA:3.40.50.880 1 221 4.3E-31 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like ALX04_RS11920 967d5d52b040c237a893ff32daac7ee4 444 PIRSF PIRSF006603 1 443 2.2E-81 T 28-03-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 ALX04_RS11920 967d5d52b040c237a893ff32daac7ee4 444 TIGRFAM TIGR00797 matE: MATE efflux family protein 20 407 2.7E-56 T 28-03-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 ALX04_RS11920 967d5d52b040c237a893ff32daac7ee4 444 Pfam PF01554 MatE 20 181 7.5E-21 T 28-03-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 ALX04_RS11920 967d5d52b040c237a893ff32daac7ee4 444 Pfam PF01554 MatE 241 395 2.2E-26 T 28-03-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 ALX04_RS07180 5f553ebd8647bf1bd50f0b255afdae84 195 Pfam PF00583 Acetyltransferase (GNAT) family 34 166 3.4E-16 T 28-03-2018 IPR000182 GNAT domain GO:0008080 ALX04_RS07180 5f553ebd8647bf1bd50f0b255afdae84 195 Gene3D G3DSA:3.40.630.30 1 193 2.7E-32 T 28-03-2018 ALX04_RS07180 5f553ebd8647bf1bd50f0b255afdae84 195 SUPERFAMILY SSF55729 2 79 6.25E-31 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase ALX04_RS07180 5f553ebd8647bf1bd50f0b255afdae84 195 SUPERFAMILY SSF55729 106 191 6.25E-31 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase ALX04_RS02605 bdd32adea70f8a91d6bc0f9222bfb704 211 Pfam PF03575 Peptidase family S51 22 206 3.1E-18 T 28-03-2018 IPR005320 Peptidase S51 GO:0006508|GO:0008236 ALX04_RS02605 bdd32adea70f8a91d6bc0f9222bfb704 211 Gene3D G3DSA:3.40.50.880 3 211 8.2E-22 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like ALX04_RS02605 bdd32adea70f8a91d6bc0f9222bfb704 211 SUPERFAMILY SSF52317 1 204 7.41E-20 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like ALX04_RS13840 7e8d10447e96b0620325858ccce6a922 448 TIGRFAM TIGR02432 lysidine_TilS_N: tRNA(Ile)-lysidine synthetase 23 206 4.9E-59 T 28-03-2018 IPR012795 tRNA(Ile)-lysidine synthase, N-terminal GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 ALX04_RS13840 7e8d10447e96b0620325858ccce6a922 448 SUPERFAMILY SSF52402 12 226 4.63E-56 T 28-03-2018 ALX04_RS13840 7e8d10447e96b0620325858ccce6a922 448 Hamap MF_01161 tRNA(Ile)-lysidine synthase [tilS]. 7 310 23.99 T 28-03-2018 IPR012094 tRNA(Ile)-lysidine synthase GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 ALX04_RS13840 7e8d10447e96b0620325858ccce6a922 448 Pfam PF01171 PP-loop family 23 202 2.3E-57 T 28-03-2018 IPR011063 tRNA(Ile)-lysidine/2-thiocytidine synthase, N-terminal Reactome: R-HSA-6782315 ALX04_RS13840 7e8d10447e96b0620325858ccce6a922 448 Pfam PF11734 TilS substrate C-terminal domain 376 433 1.3E-5 T 28-03-2018 IPR012796 Lysidine-tRNA(Ile) synthetase, C-terminal GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 ALX04_RS13840 7e8d10447e96b0620325858ccce6a922 448 TIGRFAM TIGR02433 lysidine_TilS_C: tRNA(Ile)-lysidine synthetase, C-terminal domain 374 419 6.2E-14 T 28-03-2018 IPR012796 Lysidine-tRNA(Ile) synthetase, C-terminal GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 ALX04_RS13840 7e8d10447e96b0620325858ccce6a922 448 SMART SM00977 374 444 1.9E-17 T 28-03-2018 IPR012796 Lysidine-tRNA(Ile) synthetase, C-terminal GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 ALX04_RS13840 7e8d10447e96b0620325858ccce6a922 448 SUPERFAMILY SSF56037 339 435 3.14E-10 T 28-03-2018 IPR020825 Phenylalanyl-tRNA synthetase, B3/B4 ALX04_RS13840 7e8d10447e96b0620325858ccce6a922 448 Gene3D G3DSA:3.40.50.620 18 241 2.5E-45 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold ALX04_RS07865 7f7a75b06a8343d2080d2684975eb30b 274 Pfam PF00563 EAL domain 46 260 7.5E-15 T 28-03-2018 IPR001633 EAL domain ALX04_RS07865 7f7a75b06a8343d2080d2684975eb30b 274 SMART SM00052 28 265 2.0E-7 T 28-03-2018 IPR001633 EAL domain ALX04_RS07865 7f7a75b06a8343d2080d2684975eb30b 274 SUPERFAMILY SSF141868 46 265 9.42E-27 T 28-03-2018 IPR001633 EAL domain ALX04_RS07865 7f7a75b06a8343d2080d2684975eb30b 274 Gene3D G3DSA:3.20.20.450 31 272 8.4E-25 T 28-03-2018 IPR001633 EAL domain ALX04_RS08655 040d79d7608744fc42d11d195f796bb4 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 6 23 2.2E-30 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR ALX04_RS08655 040d79d7608744fc42d11d195f796bb4 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 80 91 2.2E-30 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR ALX04_RS08655 040d79d7608744fc42d11d195f796bb4 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 153 172 2.2E-30 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR ALX04_RS08655 040d79d7608744fc42d11d195f796bb4 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 127 143 2.2E-30 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR ALX04_RS08655 040d79d7608744fc42d11d195f796bb4 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 176 193 2.2E-30 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR ALX04_RS08655 040d79d7608744fc42d11d195f796bb4 259 Gene3D G3DSA:3.40.50.720 1 40 2.8E-10 T 28-03-2018 ALX04_RS08655 040d79d7608744fc42d11d195f796bb4 259 Gene3D G3DSA:3.40.50.720 41 234 7.4E-47 T 28-03-2018 ALX04_RS08655 040d79d7608744fc42d11d195f796bb4 259 SUPERFAMILY SSF51735 3 227 3.15E-67 T 28-03-2018 IPR016040 NAD(P)-binding domain ALX04_RS08655 040d79d7608744fc42d11d195f796bb4 259 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 80 91 3.7E-11 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR ALX04_RS08655 040d79d7608744fc42d11d195f796bb4 259 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 153 172 3.7E-11 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR ALX04_RS08655 040d79d7608744fc42d11d195f796bb4 259 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 133 141 3.7E-11 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR ALX04_RS08655 040d79d7608744fc42d11d195f796bb4 259 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 5 191 0.0095 T 28-03-2018 ALX04_RS08655 040d79d7608744fc42d11d195f796bb4 259 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 140 168 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 ALX04_RS08655 040d79d7608744fc42d11d195f796bb4 259 Pfam PF00106 short chain dehydrogenase 5 198 6.9E-58 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR ALX04_RS13720 746df680e9d0fb21a03d2c9430052a4e 120 Gene3D G3DSA:3.90.470.20 1 119 3.7E-28 T 28-03-2018 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 ALX04_RS13720 746df680e9d0fb21a03d2c9430052a4e 120 TIGRFAM TIGR00556 pantethn_trn: phosphopantetheine--protein transferase domain 3 91 4.6E-20 T 28-03-2018 IPR004568 Phosphopantetheine-protein transferase domain GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1 ALX04_RS13720 746df680e9d0fb21a03d2c9430052a4e 120 SUPERFAMILY SSF56214 2 116 4.97E-30 T 28-03-2018 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 ALX04_RS13720 746df680e9d0fb21a03d2c9430052a4e 120 TIGRFAM TIGR00516 acpS: holo-[acyl-carrier-protein] synthase 2 117 1.7E-25 T 28-03-2018 IPR002582 Holo-[acyl carrier protein] synthase GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1 ALX04_RS13720 746df680e9d0fb21a03d2c9430052a4e 120 Hamap MF_00101 Holo-[acyl-carrier-protein] synthase [acpS]. 3 117 20.866 T 28-03-2018 IPR002582 Holo-[acyl carrier protein] synthase GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1 ALX04_RS13720 746df680e9d0fb21a03d2c9430052a4e 120 ProDom PD004282 TRANSFERASE SYNTHASE HOLO-ACYL-CARRIER-PROTEIN HOLO-ACP 4'-PHOSPHOPANTETHEINYL FATTY ACID METAL-BINDING MAGNESIUM LIPID 8 117 2.0E-59 T 28-03-2018 IPR004568 Phosphopantetheine-protein transferase domain GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1 ALX04_RS13720 746df680e9d0fb21a03d2c9430052a4e 120 Pfam PF01648 4'-phosphopantetheinyl transferase superfamily 5 96 1.4E-19 T 28-03-2018 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 ALX04_RS03190 68bb1ed41a5ca5f5c6f1865b7a258a1b 298 SMART SM00046 4 130 0.0034 T 28-03-2018 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 ALX04_RS03190 68bb1ed41a5ca5f5c6f1865b7a258a1b 298 Pfam PF00781 Diacylglycerol kinase catalytic domain 7 119 1.5E-22 T 28-03-2018 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 ALX04_RS03190 68bb1ed41a5ca5f5c6f1865b7a258a1b 298 Gene3D G3DSA:3.40.50.10330 1 134 2.4E-20 T 28-03-2018 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, domain 1 GO:0003951|GO:0008152 ALX04_RS03190 68bb1ed41a5ca5f5c6f1865b7a258a1b 298 SUPERFAMILY SSF111331 4 294 3.14E-49 T 28-03-2018 IPR016064 NAD kinase/diacylglycerol kinase-like domain ALX04_RS01745 e14e7797f9dae9bcbc8ef70e442027cb 267 Gene3D G3DSA:3.30.1060.10 94 264 6.4E-61 T 28-03-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 ALX04_RS01745 e14e7797f9dae9bcbc8ef70e442027cb 267 SUPERFAMILY SSF55068 89 251 2.22E-65 T 28-03-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 ALX04_RS01745 e14e7797f9dae9bcbc8ef70e442027cb 267 TIGRFAM TIGR00401 msrA: peptide-methionine (S)-S-oxide reductase 96 247 1.2E-54 T 28-03-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 ALX04_RS01745 e14e7797f9dae9bcbc8ef70e442027cb 267 Pfam PF08951 Enterocin A Immunity 7 72 8.1E-14 T 28-03-2018 IPR015046 Enterocin A Immunity ALX04_RS01745 e14e7797f9dae9bcbc8ef70e442027cb 267 Hamap MF_01401 Peptide methionine sulfoxide reductase MsrA [msrA]. 95 254 34.315 T 28-03-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 ALX04_RS01745 e14e7797f9dae9bcbc8ef70e442027cb 267 Pfam PF01625 Peptide methionine sulfoxide reductase 98 248 1.9E-57 T 28-03-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 ALX04_RS01325 766658a7020e8e3fdd71e828ba5313ea 440 SUPERFAMILY SSF51905 1 301 2.16E-44 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ALX04_RS01325 766658a7020e8e3fdd71e828ba5313ea 440 PIRSF PIRSF000350 1 432 3.5E-61 T 28-03-2018 ALX04_RS01325 766658a7020e8e3fdd71e828ba5313ea 440 Gene3D G3DSA:3.30.390.30 333 440 3.9E-11 T 28-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 ALX04_RS01325 766658a7020e8e3fdd71e828ba5313ea 440 Gene3D G3DSA:3.50.50.60 1 161 3.0E-18 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ALX04_RS01325 766658a7020e8e3fdd71e828ba5313ea 440 SUPERFAMILY SSF55424 332 439 4.3E-16 T 28-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 ALX04_RS01325 766658a7020e8e3fdd71e828ba5313ea 440 Gene3D G3DSA:3.40.50.720 162 332 1.5E-29 T 28-03-2018 ALX04_RS01325 766658a7020e8e3fdd71e828ba5313ea 440 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 5 312 3.0E-52 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ALX04_RS01325 766658a7020e8e3fdd71e828ba5313ea 440 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 7 26 2.2E-27 T 28-03-2018 ALX04_RS01325 766658a7020e8e3fdd71e828ba5313ea 440 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 278 300 2.2E-27 T 28-03-2018 ALX04_RS01325 766658a7020e8e3fdd71e828ba5313ea 440 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 250 266 2.2E-27 T 28-03-2018 ALX04_RS01325 766658a7020e8e3fdd71e828ba5313ea 440 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 167 185 2.2E-27 T 28-03-2018 ALX04_RS01325 766658a7020e8e3fdd71e828ba5313ea 440 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 130 148 2.2E-27 T 28-03-2018 ALX04_RS01325 766658a7020e8e3fdd71e828ba5313ea 440 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 293 300 1.2E-41 T 28-03-2018 ALX04_RS01325 766658a7020e8e3fdd71e828ba5313ea 440 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 392 407 1.2E-41 T 28-03-2018 ALX04_RS01325 766658a7020e8e3fdd71e828ba5313ea 440 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 133 142 1.2E-41 T 28-03-2018 ALX04_RS01325 766658a7020e8e3fdd71e828ba5313ea 440 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 167 192 1.2E-41 T 28-03-2018 ALX04_RS01325 766658a7020e8e3fdd71e828ba5313ea 440 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 331 352 1.2E-41 T 28-03-2018 ALX04_RS01325 766658a7020e8e3fdd71e828ba5313ea 440 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 6 28 1.2E-41 T 28-03-2018 ALX04_RS01325 766658a7020e8e3fdd71e828ba5313ea 440 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 251 265 1.2E-41 T 28-03-2018 ALX04_RS01325 766658a7020e8e3fdd71e828ba5313ea 440 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 38 53 1.2E-41 T 28-03-2018 ALX04_RS06900 6136c4e477e83be7f35d3bd862f641bc 526 Gene3D G3DSA:3.20.16.10 44 205 4.3E-17 T 28-03-2018 IPR035443 Herpesvirus/Caudovirus protease domain ALX04_RS06900 6136c4e477e83be7f35d3bd862f641bc 526 TIGRFAM TIGR01554 major_cap_HK97: phage major capsid protein, HK97 family 210 516 1.3E-63 T 28-03-2018 IPR024455 Phage capsid ALX04_RS06900 6136c4e477e83be7f35d3bd862f641bc 526 Pfam PF04586 Caudovirus prohead serine protease 41 196 3.7E-32 T 28-03-2018 IPR006433 Prohead protease ALX04_RS06900 6136c4e477e83be7f35d3bd862f641bc 526 SUPERFAMILY SSF56563 255 517 1.83E-42 T 28-03-2018 ALX04_RS06900 6136c4e477e83be7f35d3bd862f641bc 526 Gene3D G3DSA:3.30.2320.10 379 489 3.9E-28 T 28-03-2018 ALX04_RS06900 6136c4e477e83be7f35d3bd862f641bc 526 TIGRFAM TIGR01543 proheadase_HK97: phage prohead protease, HK97 family 48 196 1.7E-20 T 28-03-2018 IPR006433 Prohead protease ALX04_RS06900 6136c4e477e83be7f35d3bd862f641bc 526 Pfam PF05065 Phage capsid family 262 514 1.2E-27 T 28-03-2018 IPR024455 Phage capsid ALX04_RS12690 7b38d11d5f8cde4c12f19a75fddc42c5 92 Gene3D G3DSA:1.10.10.10 1 53 1.4E-4 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS12690 7b38d11d5f8cde4c12f19a75fddc42c5 92 Pfam PF09862 Protein of unknown function (DUF2089) 2 83 7.5E-15 T 28-03-2018 IPR018658 Protein of unknown function DUF2089 ALX04_RS14450 2c2a76a3443bc623c80b1f5cf0e66dbb 241 TIGRFAM TIGR03725 T6A_YeaZ: tRNA threonylcarbamoyl adenosine modification protein YeaZ 3 217 2.1E-54 T 28-03-2018 IPR022496 tRNA threonylcarbamoyl adenosine modification protein TsaB GO:0002949 ALX04_RS14450 2c2a76a3443bc623c80b1f5cf0e66dbb 241 Gene3D G3DSA:3.30.420.40 1 137 1.5E-35 T 28-03-2018 ALX04_RS14450 2c2a76a3443bc623c80b1f5cf0e66dbb 241 Pfam PF00814 Glycoprotease family 31 195 1.8E-32 T 28-03-2018 IPR000905 Gcp-like domain KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 ALX04_RS14450 2c2a76a3443bc623c80b1f5cf0e66dbb 241 SUPERFAMILY SSF53067 108 215 1.06E-12 T 28-03-2018 ALX04_RS14450 2c2a76a3443bc623c80b1f5cf0e66dbb 241 SUPERFAMILY SSF53067 1 100 6.04E-29 T 28-03-2018 ALX04_RS13440 e09769719dce38446638e41b50af0f65 338 SUPERFAMILY SSF52374 5 334 1.69E-81 T 28-03-2018 ALX04_RS13440 e09769719dce38446638e41b50af0f65 338 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 12 21 - T 28-03-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 ALX04_RS13440 e09769719dce38446638e41b50af0f65 338 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 201 211 9.9E-25 T 28-03-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 ALX04_RS13440 e09769719dce38446638e41b50af0f65 338 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 147 168 9.9E-25 T 28-03-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 ALX04_RS13440 e09769719dce38446638e41b50af0f65 338 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 69 88 9.9E-25 T 28-03-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 ALX04_RS13440 e09769719dce38446638e41b50af0f65 338 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 16 32 9.9E-25 T 28-03-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 ALX04_RS13440 e09769719dce38446638e41b50af0f65 338 Pfam PF00579 tRNA synthetases class I (W and Y) 6 287 9.6E-58 T 28-03-2018 IPR002305 Aminoacyl-tRNA synthetase, class Ic GO:0000166|GO:0004812|GO:0005524|GO:0006418 ALX04_RS13440 e09769719dce38446638e41b50af0f65 338 Gene3D G3DSA:3.40.50.620 3 220 2.7E-63 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold ALX04_RS13440 e09769719dce38446638e41b50af0f65 338 TIGRFAM TIGR00233 trpS: tryptophan--tRNA ligase 3 334 2.1E-76 T 28-03-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 ALX04_RS13440 e09769719dce38446638e41b50af0f65 338 Gene3D G3DSA:1.10.240.10 221 326 8.9E-28 T 28-03-2018 ALX04_RS07995 501393955bc4e07d6927b2f4af5276ae 292 SUPERFAMILY SSF52540 3 218 8.62E-39 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase ALX04_RS07995 501393955bc4e07d6927b2f4af5276ae 292 Gene3D G3DSA:3.40.50.300 1 230 2.5E-38 T 28-03-2018 ALX04_RS07995 501393955bc4e07d6927b2f4af5276ae 292 SMART SM00382 27 211 2.1E-6 T 28-03-2018 IPR003593 AAA+ ATPase domain ALX04_RS07995 501393955bc4e07d6927b2f4af5276ae 292 Pfam PF00005 ABC transporter 18 155 3.3E-18 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 ALX04_RS13860 2023e27a3c5af12244c0c8baed5e71aa 335 TIGRFAM TIGR00737 nifR3_yhdG: putative TIM-barrel protein, nifR3 family 7 324 7.3E-116 T 28-03-2018 IPR004652 tRNA-dihydrouridine synthase, TIM-barrel, NifR3 GO:0008033|GO:0016491|GO:0050660|GO:0055114 ALX04_RS13860 2023e27a3c5af12244c0c8baed5e71aa 335 PIRSF PIRSF006621 4 333 1.9E-101 T 28-03-2018 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 ALX04_RS13860 2023e27a3c5af12244c0c8baed5e71aa 335 Gene3D G3DSA:1.10.1200.80 258 334 9.4E-14 T 28-03-2018 IPR024036 tRNA-dihydrouridine synthase, putative, C-terminal GO:0016491|GO:0055114 ALX04_RS13860 2023e27a3c5af12244c0c8baed5e71aa 335 SUPERFAMILY SSF51395 14 323 3.11E-88 T 28-03-2018 ALX04_RS13860 2023e27a3c5af12244c0c8baed5e71aa 335 Pfam PF01207 Dihydrouridine synthase (Dus) 18 319 5.6E-92 T 28-03-2018 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 ALX04_RS13860 2023e27a3c5af12244c0c8baed5e71aa 335 Gene3D G3DSA:3.20.20.70 25 251 6.3E-58 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 ALX04_RS13860 2023e27a3c5af12244c0c8baed5e71aa 335 Gene3D G3DSA:3.20.20.70 1 24 0.019 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 ALX04_RS13860 2023e27a3c5af12244c0c8baed5e71aa 335 ProSitePatterns PS01136 Uncharacterized protein family UPF0034 signature. 99 117 - T 28-03-2018 IPR018517 tRNA-dihydrouridine synthase, conserved site GO:0008033|GO:0017150|GO:0050660|GO:0055114 ALX04_RS12005 31d6d638fa7951ab8956c8edaee3ffff 246 Gene3D G3DSA:3.40.50.7700 109 246 2.0E-38 T 28-03-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 ALX04_RS12005 31d6d638fa7951ab8956c8edaee3ffff 246 SMART SM01001 117 246 3.1E-36 T 28-03-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 ALX04_RS12005 31d6d638fa7951ab8956c8edaee3ffff 246 Pfam PF00731 AIR carboxylase 119 243 7.7E-15 T 28-03-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 ALX04_RS12005 31d6d638fa7951ab8956c8edaee3ffff 246 SUPERFAMILY SSF52255 117 245 1.96E-28 T 28-03-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 ALX04_RS13905 27225cabda3a03b4a6da9db5db441dea 490 Pfam PF00854 POT family 89 458 1.2E-71 T 28-03-2018 IPR000109 Proton-dependent oligopeptide transporter family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-427975 ALX04_RS13905 27225cabda3a03b4a6da9db5db441dea 490 ProSitePatterns PS01022 PTR2 family proton/oligopeptide symporters signature 1. 77 101 - T 28-03-2018 IPR018456 PTR2 family proton/oligopeptide symporter, conserved site GO:0005215|GO:0006857|GO:0016020 Reactome: R-HSA-427975 ALX04_RS13905 27225cabda3a03b4a6da9db5db441dea 490 Gene3D G3DSA:1.20.1250.20 3 202 1.4E-21 T 28-03-2018 ALX04_RS13905 27225cabda3a03b4a6da9db5db441dea 490 ProSitePatterns PS01023 PTR2 family proton/oligopeptide symporters signature 2. 151 163 - T 28-03-2018 IPR018456 PTR2 family proton/oligopeptide symporter, conserved site GO:0005215|GO:0006857|GO:0016020 Reactome: R-HSA-427975 ALX04_RS13905 27225cabda3a03b4a6da9db5db441dea 490 SUPERFAMILY SSF103473 5 203 3.01E-31 T 28-03-2018 IPR020846 Major facilitator superfamily domain ALX04_RS13905 27225cabda3a03b4a6da9db5db441dea 490 SUPERFAMILY SSF103473 275 482 3.01E-31 T 28-03-2018 IPR020846 Major facilitator superfamily domain ALX04_RS13905 27225cabda3a03b4a6da9db5db441dea 490 Gene3D G3DSA:1.20.1250.20 275 489 5.4E-16 T 28-03-2018 ALX04_RS13905 27225cabda3a03b4a6da9db5db441dea 490 TIGRFAM TIGR00924 yjdL_sub1_fam: amino acid/peptide transporter (Peptide:H+ symporter) 9 486 1.2E-128 T 28-03-2018 IPR005279 Dipeptide/tripeptide permease GO:0015197|GO:0015833|GO:0016020 ALX04_RS03210 81c84da6650dc291e22bb2042750c465 73 Pfam PF05532 CsbD-like 7 57 6.9E-14 T 28-03-2018 IPR008462 CsbD-like domain ALX04_RS03210 81c84da6650dc291e22bb2042750c465 73 SUPERFAMILY SSF69047 6 68 7.19E-11 T 28-03-2018 IPR008462 CsbD-like domain ALX04_RS03210 81c84da6650dc291e22bb2042750c465 73 Gene3D G3DSA:1.10.1470.10 4 71 1.2E-14 T 28-03-2018 IPR008462 CsbD-like domain ALX04_RS15615 8e29d2d0d8dcba2c87228bd0e63bf2d7 100 Gene3D G3DSA:3.30.2310.20 1 100 2.5E-18 T 28-03-2018 ALX04_RS15615 8e29d2d0d8dcba2c87228bd0e63bf2d7 100 Pfam PF15738 Bacterial toxin of type II toxin-antitoxin system, YafQ 1 98 1.8E-22 T 28-03-2018 IPR004386 Toxin-antitoxin system, YafQ-like toxin ALX04_RS15615 8e29d2d0d8dcba2c87228bd0e63bf2d7 100 TIGRFAM TIGR02385 RelE_StbE: addiction module toxin, RelE/StbE family 2 95 1.8E-13 T 28-03-2018 IPR007712 Toxin-antitoxin system, RelE/ParE toxin family ALX04_RS15615 8e29d2d0d8dcba2c87228bd0e63bf2d7 100 SUPERFAMILY SSF143011 2 96 4.45E-14 T 28-03-2018 IPR035095 Toxin RelE-like domain ALX04_RS04290 688a955ed8f00cad566fc5945c86f0f2 137 PIRSF PIRSF021328 2 137 1.6E-41 T 28-03-2018 IPR016787 Uncharacterised conserved protein UCP021328 ALX04_RS04290 688a955ed8f00cad566fc5945c86f0f2 137 Pfam PF11208 Protein of unknown function (DUF2992) 7 137 2.0E-32 T 28-03-2018 IPR016787 Uncharacterised conserved protein UCP021328 ALX04_RS14385 42d2b79f0f2750c7fa68e5c4a72b0956 221 Pfam PF02223 Thymidylate kinase 9 200 2.3E-51 T 28-03-2018 ALX04_RS14385 42d2b79f0f2750c7fa68e5c4a72b0956 221 Gene3D G3DSA:3.40.50.300 1 216 4.0E-53 T 28-03-2018 ALX04_RS14385 42d2b79f0f2750c7fa68e5c4a72b0956 221 Hamap MF_00165 Thymidylate kinase [tmk]. 5 209 29.622 T 28-03-2018 IPR018094 Thymidylate kinase GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 ALX04_RS14385 42d2b79f0f2750c7fa68e5c4a72b0956 221 SUPERFAMILY SSF52540 3 209 2.57E-51 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase ALX04_RS14385 42d2b79f0f2750c7fa68e5c4a72b0956 221 ProSitePatterns PS01331 Thymidylate kinase signature. 95 107 - T 28-03-2018 IPR018095 Thymidylate kinase, conserved site GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 ALX04_RS14385 42d2b79f0f2750c7fa68e5c4a72b0956 221 TIGRFAM TIGR00041 DTMP_kinase: dTMP kinase 1 198 1.1E-58 T 28-03-2018 IPR018094 Thymidylate kinase GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 ALX04_RS03530 06da9291a27e43356af9eba64bece00e 853 Gene3D G3DSA:1.10.1030.10 401 531 5.7E-33 T 28-03-2018 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 ALX04_RS03530 06da9291a27e43356af9eba64bece00e 853 SUPERFAMILY SSF52440 551 651 2.45E-18 T 28-03-2018 IPR016185 Pre-ATP-grasp domain ALX04_RS03530 06da9291a27e43356af9eba64bece00e 853 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 238 255 1.3E-28 T 28-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 ALX04_RS03530 06da9291a27e43356af9eba64bece00e 853 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 295 324 1.3E-28 T 28-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 ALX04_RS03530 06da9291a27e43356af9eba64bece00e 853 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 18 32 1.3E-28 T 28-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 ALX04_RS03530 06da9291a27e43356af9eba64bece00e 853 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 203 222 1.3E-28 T 28-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 ALX04_RS03530 06da9291a27e43356af9eba64bece00e 853 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 378 396 1.3E-28 T 28-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 ALX04_RS03530 06da9291a27e43356af9eba64bece00e 853 SUPERFAMILY SSF56059 130 399 1.48E-70 T 28-03-2018 ALX04_RS03530 06da9291a27e43356af9eba64bece00e 853 SMART SM01096 420 540 2.8E-34 T 28-03-2018 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 ALX04_RS03530 06da9291a27e43356af9eba64bece00e 853 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 132 332 8.6E-43 T 28-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 ALX04_RS03530 06da9291a27e43356af9eba64bece00e 853 SUPERFAMILY SSF56059 669 842 3.09E-9 T 28-03-2018 ALX04_RS03530 06da9291a27e43356af9eba64bece00e 853 Gene3D G3DSA:3.30.470.20 653 848 3.7E-6 T 28-03-2018 ALX04_RS03530 06da9291a27e43356af9eba64bece00e 853 Pfam PF02787 Carbamoyl-phosphate synthetase large chain, oligomerisation domain 423 540 6.7E-27 T 28-03-2018 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 ALX04_RS03530 06da9291a27e43356af9eba64bece00e 853 SUPERFAMILY SSF52440 5 124 1.25E-25 T 28-03-2018 IPR016185 Pre-ATP-grasp domain ALX04_RS03530 06da9291a27e43356af9eba64bece00e 853 SUPERFAMILY SSF48108 395 547 1.31E-35 T 28-03-2018 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 ALX04_RS03530 06da9291a27e43356af9eba64bece00e 853 Gene3D G3DSA:3.30.470.20 119 400 1.6E-35 T 28-03-2018 ALX04_RS03530 06da9291a27e43356af9eba64bece00e 853 Gene3D G3DSA:3.40.50.20 1 114 4.6E-19 T 28-03-2018 ALX04_RS03530 06da9291a27e43356af9eba64bece00e 853 Gene3D G3DSA:3.40.50.20 532 652 1.6E-21 T 28-03-2018 ALX04_RS03575 03f62f1a6f6bf10d807ee7fa0914340c 568 Gene3D G3DSA:2.30.310.10 1 167 3.7E-51 T 28-03-2018 ALX04_RS03575 03f62f1a6f6bf10d807ee7fa0914340c 568 Pfam PF05833 Fibronectin-binding protein A N-terminus (FbpA) 4 440 1.4E-152 T 28-03-2018 ALX04_RS03575 03f62f1a6f6bf10d807ee7fa0914340c 568 Gene3D G3DSA:3.40.970.40 239 287 2.9E-9 T 28-03-2018 ALX04_RS03575 03f62f1a6f6bf10d807ee7fa0914340c 568 Gene3D G3DSA:1.10.8.50 168 238 1.9E-5 T 28-03-2018 ALX04_RS03575 03f62f1a6f6bf10d807ee7fa0914340c 568 Pfam PF05670 Domain of unknown function (DUF814) 450 535 2.7E-26 T 28-03-2018 IPR008532 Domain of unknown function DUF814 ALX04_RS12340 247fb355c48e4d1a654c4cb79e6aee05 368 Pfam PF00005 ABC transporter 22 164 5.5E-30 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 ALX04_RS12340 247fb355c48e4d1a654c4cb79e6aee05 368 Gene3D G3DSA:3.40.50.300 2 242 6.8E-68 T 28-03-2018 ALX04_RS12340 247fb355c48e4d1a654c4cb79e6aee05 368 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 ALX04_RS12340 247fb355c48e4d1a654c4cb79e6aee05 368 SMART SM00382 30 214 1.4E-12 T 28-03-2018 IPR003593 AAA+ ATPase domain ALX04_RS12340 247fb355c48e4d1a654c4cb79e6aee05 368 Pfam PF08402 TOBE domain 284 359 1.8E-7 T 28-03-2018 IPR013611 Transport-associated OB, type 2 GO:0005215|GO:0005524|GO:0006810|GO:0016820|GO:0043190 ALX04_RS12340 247fb355c48e4d1a654c4cb79e6aee05 368 SUPERFAMILY SSF50331 239 367 1.07E-25 T 28-03-2018 IPR008995 Molybdate/tungstate binding, C-terminal ALX04_RS12340 247fb355c48e4d1a654c4cb79e6aee05 368 SUPERFAMILY SSF52540 5 246 1.1E-81 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase ALX04_RS12340 247fb355c48e4d1a654c4cb79e6aee05 368 Gene3D G3DSA:2.40.50.140 297 352 6.8E-12 T 28-03-2018 ALX04_RS12340 247fb355c48e4d1a654c4cb79e6aee05 368 Gene3D G3DSA:2.40.50.100 243 296 1.4E-13 T 28-03-2018 ALX04_RS03605 d37c8e5950b2b584ff520a079df25a97 96 SUPERFAMILY SSF143100 10 56 1.57E-6 T 28-03-2018 IPR035069 TTHA1013/TTHA0281-like ALX04_RS03605 d37c8e5950b2b584ff520a079df25a97 96 Gene3D G3DSA:3.30.2390.10 8 78 3.2E-7 T 28-03-2018 IPR035069 TTHA1013/TTHA0281-like ALX04_RS15215 a27248038c746b5b4e9e49b07e85076b 253 Pfam PF01925 Sulfite exporter TauE/SafE 13 251 1.3E-28 T 28-03-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 ALX04_RS08440 493841c914e1f72a0ee544662a6887f7 514 Pfam PF00534 Glycosyl transferases group 1 327 481 1.4E-32 T 28-03-2018 IPR001296 Glycosyl transferase, family 1 ALX04_RS08440 493841c914e1f72a0ee544662a6887f7 514 Gene3D G3DSA:3.40.50.2000 313 486 6.9E-34 T 28-03-2018 ALX04_RS08440 493841c914e1f72a0ee544662a6887f7 514 SUPERFAMILY SSF53756 201 498 1.88E-51 T 28-03-2018 ALX04_RS03045 1f3a8863e5f3f78cb3db9d6178ee5ed4 410 SUPERFAMILY SSF53901 213 407 1.5E-65 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 ALX04_RS03045 1f3a8863e5f3f78cb3db9d6178ee5ed4 410 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 3 245 1.6E-51 T 28-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal ALX04_RS03045 1f3a8863e5f3f78cb3db9d6178ee5ed4 410 PIRSF PIRSF000447 1 409 5.3E-157 T 28-03-2018 IPR017568 3-oxoacyl-[acyl-carrier-protein] synthase 2 GO:0006633|GO:0016747 ALX04_RS03045 1f3a8863e5f3f78cb3db9d6178ee5ed4 410 SMART SM00825 Beta-ketoacyl synthase 5 398 1.6E-13 T 28-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain ALX04_RS03045 1f3a8863e5f3f78cb3db9d6178ee5ed4 410 TIGRFAM TIGR03150 fabF: beta-ketoacyl-acyl-carrier-protein synthase II 3 405 1.2E-172 T 28-03-2018 IPR017568 3-oxoacyl-[acyl-carrier-protein] synthase 2 GO:0006633|GO:0016747 ALX04_RS03045 1f3a8863e5f3f78cb3db9d6178ee5ed4 410 Gene3D G3DSA:3.40.47.10 1 257 1.3E-71 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 ALX04_RS03045 1f3a8863e5f3f78cb3db9d6178ee5ed4 410 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 253 364 3.9E-36 T 28-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal ALX04_RS03045 1f3a8863e5f3f78cb3db9d6178ee5ed4 410 SUPERFAMILY SSF53901 3 250 4.45E-69 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 ALX04_RS03045 1f3a8863e5f3f78cb3db9d6178ee5ed4 410 Gene3D G3DSA:3.40.47.10 261 409 1.2E-49 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 ALX04_RS04460 26d3b1de7e1359088e8bee0048c65412 316 Hamap MF_00735 Ribosomal protein L11 methyltransferase [prmA]. 3 311 34.882 T 28-03-2018 IPR004498 Ribosomal protein L11 methyltransferase GO:0006479|GO:0008276 ALX04_RS04460 26d3b1de7e1359088e8bee0048c65412 316 Gene3D G3DSA:3.40.50.150 116 315 1.2E-35 T 28-03-2018 ALX04_RS04460 26d3b1de7e1359088e8bee0048c65412 316 SUPERFAMILY SSF53335 68 307 5.52E-40 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase ALX04_RS04460 26d3b1de7e1359088e8bee0048c65412 316 Pfam PF06325 Ribosomal protein L11 methyltransferase (PrmA) 2 308 3.1E-96 T 28-03-2018 ALX04_RS04460 26d3b1de7e1359088e8bee0048c65412 316 TIGRFAM TIGR00406 prmA: ribosomal protein L11 methyltransferase 3 304 3.6E-79 T 28-03-2018 IPR004498 Ribosomal protein L11 methyltransferase GO:0006479|GO:0008276 ALX04_RS04460 26d3b1de7e1359088e8bee0048c65412 316 PIRSF PIRSF000401 1 313 5.1E-118 T 28-03-2018 IPR004498 Ribosomal protein L11 methyltransferase GO:0006479|GO:0008276 ALX04_RS13465 468ccca2e23f5a98967cf52994ea0bf8 451 Pfam PF02378 Phosphotransferase system, EIIC 29 362 6.2E-51 T 28-03-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 ALX04_RS13465 468ccca2e23f5a98967cf52994ea0bf8 451 TIGRFAM TIGR00410 lacE: PTS system, lactose/cellobiose family IIC component 12 434 1.8E-99 T 28-03-2018 IPR004501 Phosphotransferase system, EIIC component, type 3 GO:0008982|GO:0009401|GO:0016021 ALX04_RS13465 468ccca2e23f5a98967cf52994ea0bf8 451 PIRSF PIRSF006351 1 447 5.8E-124 T 28-03-2018 IPR004796 Phosphotransferase system, cellobiose-type IIC component GO:0008982|GO:0009401|GO:0016021 ALX04_RS07450 1137bbda029a964fb500303dfaab6c2f 287 SUPERFAMILY SSF46689 7 72 4.3E-15 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 ALX04_RS07450 1137bbda029a964fb500303dfaab6c2f 287 Gene3D G3DSA:1.10.10.10 1 70 2.6E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS07450 1137bbda029a964fb500303dfaab6c2f 287 Pfam PF01380 SIS domain 128 245 1.1E-13 T 28-03-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 ALX04_RS07450 1137bbda029a964fb500303dfaab6c2f 287 Gene3D G3DSA:3.40.50.10490 71 281 1.7E-22 T 28-03-2018 ALX04_RS07450 1137bbda029a964fb500303dfaab6c2f 287 SUPERFAMILY SSF53697 97 270 6.67E-23 T 28-03-2018 ALX04_RS07450 1137bbda029a964fb500303dfaab6c2f 287 Pfam PF01418 Helix-turn-helix domain, rpiR family 8 72 9.0E-14 T 28-03-2018 IPR000281 Helix-turn-helix protein RpiR GO:0003700|GO:0006355 ALX04_RS05250 0f948137c6b059e7623240d98753a6cf 763 Gene3D G3DSA:3.60.15.10 478 721 9.9E-21 T 28-03-2018 IPR001279 Metallo-beta-lactamase ALX04_RS05250 0f948137c6b059e7623240d98753a6cf 763 Pfam PF03772 Competence protein 211 454 4.3E-28 T 28-03-2018 IPR004477 ComEC/Rec2-related protein ALX04_RS05250 0f948137c6b059e7623240d98753a6cf 763 SUPERFAMILY SSF56281 484 732 9.86E-40 T 28-03-2018 IPR001279 Metallo-beta-lactamase ALX04_RS05250 0f948137c6b059e7623240d98753a6cf 763 TIGRFAM TIGR00360 ComEC_N-term: ComEC/Rec2-related protein 233 393 1.3E-11 T 28-03-2018 IPR004477 ComEC/Rec2-related protein ALX04_RS05250 0f948137c6b059e7623240d98753a6cf 763 SMART SM00849 491 698 2.5E-5 T 28-03-2018 IPR001279 Metallo-beta-lactamase ALX04_RS05250 0f948137c6b059e7623240d98753a6cf 763 Pfam PF13567 Domain of unknown function (DUF4131) 20 170 6.4E-10 T 28-03-2018 IPR025405 Domain of unknown function DUF4131 ALX04_RS05250 0f948137c6b059e7623240d98753a6cf 763 Pfam PF00753 Metallo-beta-lactamase superfamily 489 693 2.3E-10 T 28-03-2018 IPR001279 Metallo-beta-lactamase ALX04_RS05250 0f948137c6b059e7623240d98753a6cf 763 TIGRFAM TIGR00361 ComEC_Rec2: DNA internalization-related competence protein ComEC/Rec2 91 727 1.9E-59 T 28-03-2018 IPR004797 Competence protein ComEC/Rec2 GO:0016021|GO:0030420 ALX04_RS15225 97b37a3f9f49a64846ba4db729d87f91 431 Hamap MF_00900 GTPase HflX [hflX]. 28 400 43.275 T 28-03-2018 IPR016496 GTPase HflX GO:0005525 ALX04_RS15225 97b37a3f9f49a64846ba4db729d87f91 431 Pfam PF13167 GTP-binding GTPase N-terminal 27 112 4.2E-26 T 28-03-2018 IPR025121 GTPase HflX, N-terminal ALX04_RS15225 97b37a3f9f49a64846ba4db729d87f91 431 TIGRFAM TIGR03156 GTP_HflX: GTP-binding protein HflX 12 370 2.7E-118 T 28-03-2018 IPR016496 GTPase HflX GO:0005525 ALX04_RS15225 97b37a3f9f49a64846ba4db729d87f91 431 Pfam PF16360 GTP-binding GTPase Middle Region 115 201 5.3E-25 T 28-03-2018 IPR032305 GTP-binding protein, middle domain ALX04_RS15225 97b37a3f9f49a64846ba4db729d87f91 431 Pfam PF01926 50S ribosome-binding GTPase 208 334 5.0E-16 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 ALX04_RS15225 97b37a3f9f49a64846ba4db729d87f91 431 Gene3D G3DSA:1.20.120.430 62 218 0.063 T 28-03-2018 ALX04_RS15225 97b37a3f9f49a64846ba4db729d87f91 431 PIRSF PIRSF006809 1 431 2.1E-138 T 28-03-2018 IPR016496 GTPase HflX GO:0005525 ALX04_RS15225 97b37a3f9f49a64846ba4db729d87f91 431 SUPERFAMILY SSF52540 206 375 9.88E-29 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase ALX04_RS15225 97b37a3f9f49a64846ba4db729d87f91 431 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 283 301 3.2E-5 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 ALX04_RS15225 97b37a3f9f49a64846ba4db729d87f91 431 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 209 229 3.2E-5 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 ALX04_RS15225 97b37a3f9f49a64846ba4db729d87f91 431 Gene3D G3DSA:3.40.50.300 219 402 2.5E-21 T 28-03-2018 ALX04_RS08360 def5b5bcad3a6c3bae68365346c653e8 226 ProSitePatterns PS00211 ABC transporters family signature. 144 158 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 ALX04_RS08360 def5b5bcad3a6c3bae68365346c653e8 226 SUPERFAMILY SSF52540 6 223 4.57E-58 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase ALX04_RS08360 def5b5bcad3a6c3bae68365346c653e8 226 Gene3D G3DSA:3.40.50.300 1 226 4.4E-59 T 28-03-2018 ALX04_RS08360 def5b5bcad3a6c3bae68365346c653e8 226 SMART SM00382 34 218 2.6E-18 T 28-03-2018 IPR003593 AAA+ ATPase domain ALX04_RS08360 def5b5bcad3a6c3bae68365346c653e8 226 Pfam PF00005 ABC transporter 25 172 6.0E-33 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 ALX04_RS01690 6470d0c417569aba342862bbff8c21a8 276 Gene3D G3DSA:1.10.3720.10 13 268 1.7E-34 T 28-03-2018 ALX04_RS01690 6470d0c417569aba342862bbff8c21a8 276 SUPERFAMILY SSF161098 8 276 1.21E-59 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 ALX04_RS01690 6470d0c417569aba342862bbff8c21a8 276 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 87 268 8.2E-20 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 ALX04_RS15815 87be548b30ce819377ccf35cc3eb7463 278 PIRSF PIRSF006483 1 267 4.1E-80 T 28-03-2018 IPR003740 Uncharacterised membrane protein YitT ALX04_RS15815 87be548b30ce819377ccf35cc3eb7463 278 Pfam PF10035 Uncharacterized protein conserved in bacteria (DUF2179) 205 259 1.8E-20 T 28-03-2018 IPR019264 Domain of unknown function DUF2179 ALX04_RS15815 87be548b30ce819377ccf35cc3eb7463 278 Pfam PF02588 Uncharacterised 5xTM membrane BCR, YitT family COG1284 1 199 1.5E-58 T 28-03-2018 IPR003740 Uncharacterised membrane protein YitT ALX04_RS11360 f03019c40e45446e06f5df674632f3d0 484 PRINTS PR00067 Catalase signature 122 140 9.6E-70 T 28-03-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 ALX04_RS11360 f03019c40e45446e06f5df674632f3d0 484 PRINTS PR00067 Catalase signature 103 120 9.6E-70 T 28-03-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 ALX04_RS11360 f03019c40e45446e06f5df674632f3d0 484 PRINTS PR00067 Catalase signature 287 314 9.6E-70 T 28-03-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 ALX04_RS11360 f03019c40e45446e06f5df674632f3d0 484 PRINTS PR00067 Catalase signature 82 100 9.6E-70 T 28-03-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 ALX04_RS11360 f03019c40e45446e06f5df674632f3d0 484 PRINTS PR00067 Catalase signature 319 345 9.6E-70 T 28-03-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 ALX04_RS11360 f03019c40e45446e06f5df674632f3d0 484 PRINTS PR00067 Catalase signature 19 42 9.6E-70 T 28-03-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 ALX04_RS11360 f03019c40e45446e06f5df674632f3d0 484 ProSitePatterns PS00438 Catalase proximal active site signature. 42 58 - T 28-03-2018 IPR024708 Catalase active site GO:0004096 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 ALX04_RS11360 f03019c40e45446e06f5df674632f3d0 484 Pfam PF06628 Catalase-related immune-responsive 415 474 1.6E-17 T 28-03-2018 IPR010582 Catalase immune-responsive domain KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 ALX04_RS11360 f03019c40e45446e06f5df674632f3d0 484 Pfam PF00199 Catalase 6 385 1.9E-187 T 28-03-2018 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 ALX04_RS11360 f03019c40e45446e06f5df674632f3d0 484 SMART SM01060 6 389 7.3E-272 T 28-03-2018 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 ALX04_RS11360 f03019c40e45446e06f5df674632f3d0 484 PIRSF PIRSF038928 1 479 3.8E-215 T 28-03-2018 IPR024711 Catalase, mono-functional, haem-containing, clades 1 and 3 GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 ALX04_RS11360 f03019c40e45446e06f5df674632f3d0 484 SUPERFAMILY SSF56634 4 481 3.53E-205 T 28-03-2018 IPR020835 Catalase-like domain GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 ALX04_RS11360 f03019c40e45446e06f5df674632f3d0 484 ProSitePatterns PS00437 Catalase proximal heme-ligand signature. 332 340 - T 28-03-2018 IPR002226 Catalase haem-binding site GO:0020037 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 ALX04_RS11360 f03019c40e45446e06f5df674632f3d0 484 Gene3D G3DSA:2.40.180.10 1 356 3.6E-161 T 28-03-2018 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 ALX04_RS09540 9f7867427e70ba898c8d1295181cd970 248 Pfam PF04397 LytTr DNA-binding domain 152 241 2.0E-14 T 28-03-2018 IPR007492 LytTR DNA-binding domain GO:0003677 ALX04_RS09540 9f7867427e70ba898c8d1295181cd970 248 SMART SM00448 2 122 5.2E-12 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 ALX04_RS09540 9f7867427e70ba898c8d1295181cd970 248 SMART SM00850 150 244 4.8E-14 T 28-03-2018 IPR007492 LytTR DNA-binding domain GO:0003677 ALX04_RS09540 9f7867427e70ba898c8d1295181cd970 248 Gene3D G3DSA:3.40.50.2300 1 142 2.8E-14 T 28-03-2018 ALX04_RS09540 9f7867427e70ba898c8d1295181cd970 248 Gene3D G3DSA:2.40.50.40 143 209 3.4E-13 T 28-03-2018 ALX04_RS09540 9f7867427e70ba898c8d1295181cd970 248 SUPERFAMILY SSF52172 1 130 1.01E-12 T 28-03-2018 IPR011006 CheY-like superfamily ALX04_RS09540 9f7867427e70ba898c8d1295181cd970 248 Pfam PF00072 Response regulator receiver domain 4 115 7.7E-13 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 ALX04_RS09855 0312312f2f4e5f41c41594f099df3e92 386 SMART SM00387 262 373 1.5E-31 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain ALX04_RS09855 0312312f2f4e5f41c41594f099df3e92 386 SMART SM00388 149 216 7.0E-12 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 ALX04_RS09855 0312312f2f4e5f41c41594f099df3e92 386 SUPERFAMILY SSF55874 205 374 5.24E-37 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain ALX04_RS09855 0312312f2f4e5f41c41594f099df3e92 386 SUPERFAMILY SSF47384 133 213 5.1E-16 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 ALX04_RS09855 0312312f2f4e5f41c41594f099df3e92 386 PRINTS PR00344 Bacterial sensor protein C-terminal signature 317 327 3.5E-13 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 ALX04_RS09855 0312312f2f4e5f41c41594f099df3e92 386 PRINTS PR00344 Bacterial sensor protein C-terminal signature 357 370 3.5E-13 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 ALX04_RS09855 0312312f2f4e5f41c41594f099df3e92 386 PRINTS PR00344 Bacterial sensor protein C-terminal signature 299 313 3.5E-13 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 ALX04_RS09855 0312312f2f4e5f41c41594f099df3e92 386 PRINTS PR00344 Bacterial sensor protein C-terminal signature 334 352 3.5E-13 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 ALX04_RS09855 0312312f2f4e5f41c41594f099df3e92 386 Gene3D G3DSA:3.30.565.10 220 382 3.5E-38 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain ALX04_RS09855 0312312f2f4e5f41c41594f099df3e92 386 Pfam PF00512 His Kinase A (phospho-acceptor) domain 149 214 1.2E-11 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 ALX04_RS09855 0312312f2f4e5f41c41594f099df3e92 386 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 263 371 2.0E-20 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain ALX04_RS09855 0312312f2f4e5f41c41594f099df3e92 386 Gene3D G3DSA:1.10.287.130 139 212 1.5E-14 T 28-03-2018 ALX04_RS10030 9490eadb112cf6d2c255816ecd3ded38 274 Pfam PF08282 haloacid dehalogenase-like hydrolase 5 262 1.7E-55 T 28-03-2018 IPR023214 HAD-like domain ALX04_RS10030 9490eadb112cf6d2c255816ecd3ded38 274 SUPERFAMILY SSF56784 1 269 1.61E-59 T 28-03-2018 IPR023214 HAD-like domain ALX04_RS10030 9490eadb112cf6d2c255816ecd3ded38 274 ProSitePatterns PS01229 Hypothetical cof family signature 2. 219 241 - T 28-03-2018 ALX04_RS10030 9490eadb112cf6d2c255816ecd3ded38 274 Gene3D G3DSA:3.40.50.1000 1 257 6.4E-38 T 28-03-2018 IPR023214 HAD-like domain ALX04_RS10030 9490eadb112cf6d2c255816ecd3ded38 274 TIGRFAM TIGR00099 Cof-subfamily: Cof-like hydrolase 4 263 1.1E-50 T 28-03-2018 IPR000150 Cof family GO:0016787 ALX04_RS10030 9490eadb112cf6d2c255816ecd3ded38 274 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 4 238 2.3E-27 T 28-03-2018 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 ALX04_RS00810 cae9a036d5549a418e14dd5397e67a33 586 TIGRFAM TIGR02868 CydC: thiol reductant ABC exporter, CydC subunit 12 536 4.0E-148 T 28-03-2018 IPR014223 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease/ATP-binding protein CydC GO:0006810|GO:0016021|GO:0042626 ALX04_RS00810 cae9a036d5549a418e14dd5397e67a33 586 Gene3D G3DSA:1.20.1560.10 5 329 3.0E-27 T 28-03-2018 ALX04_RS00810 cae9a036d5549a418e14dd5397e67a33 586 Pfam PF00005 ABC transporter 359 505 1.8E-31 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 ALX04_RS00810 cae9a036d5549a418e14dd5397e67a33 586 ProSitePatterns PS00211 ABC transporters family signature. 478 492 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 ALX04_RS00810 cae9a036d5549a418e14dd5397e67a33 586 Gene3D G3DSA:3.40.50.300 330 582 3.7E-61 T 28-03-2018 ALX04_RS00810 cae9a036d5549a418e14dd5397e67a33 586 Pfam PF00664 ABC transporter transmembrane region 86 212 2.3E-7 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 ALX04_RS00810 cae9a036d5549a418e14dd5397e67a33 586 SUPERFAMILY SSF52540 333 575 1.84E-66 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase ALX04_RS00810 cae9a036d5549a418e14dd5397e67a33 586 SUPERFAMILY SSF90123 13 322 2.49E-41 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 ALX04_RS00810 cae9a036d5549a418e14dd5397e67a33 586 SMART SM00382 367 560 1.3E-13 T 28-03-2018 IPR003593 AAA+ ATPase domain ALX04_RS03870 996b6719d02b921690f9078bdcdf68d1 316 PRINTS PR00108 Thymidylate synthase family signature 193 208 1.4E-49 T 28-03-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 ALX04_RS03870 996b6719d02b921690f9078bdcdf68d1 316 PRINTS PR00108 Thymidylate synthase family signature 249 266 1.4E-49 T 28-03-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 ALX04_RS03870 996b6719d02b921690f9078bdcdf68d1 316 PRINTS PR00108 Thymidylate synthase family signature 211 237 1.4E-49 T 28-03-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 ALX04_RS03870 996b6719d02b921690f9078bdcdf68d1 316 PRINTS PR00108 Thymidylate synthase family signature 167 186 1.4E-49 T 28-03-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 ALX04_RS03870 996b6719d02b921690f9078bdcdf68d1 316 PRINTS PR00108 Thymidylate synthase family signature 44 65 1.4E-49 T 28-03-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 ALX04_RS03870 996b6719d02b921690f9078bdcdf68d1 316 Hamap MF_00008 Thymidylate synthase [thyA]. 3 316 39.029 T 28-03-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 ALX04_RS03870 996b6719d02b921690f9078bdcdf68d1 316 Pfam PF00303 Thymidylate synthase 5 316 5.8E-119 T 28-03-2018 IPR023451 Thymidylate synthase/dCMP hydroxymethylase domain KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 ALX04_RS03870 996b6719d02b921690f9078bdcdf68d1 316 TIGRFAM TIGR03284 thym_sym: thymidylate synthase 5 316 1.1E-166 T 28-03-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 ALX04_RS03870 996b6719d02b921690f9078bdcdf68d1 316 ProSitePatterns PS00091 Thymidylate synthase active site. 178 206 - T 28-03-2018 IPR020940 Thymidylate synthase, active site GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 ALX04_RS03870 996b6719d02b921690f9078bdcdf68d1 316 SUPERFAMILY SSF55831 2 316 4.19E-135 T 28-03-2018 IPR023451 Thymidylate synthase/dCMP hydroxymethylase domain KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 ALX04_RS03870 996b6719d02b921690f9078bdcdf68d1 316 Gene3D G3DSA:3.30.572.10 2 316 3.8E-131 T 28-03-2018 IPR023451 Thymidylate synthase/dCMP hydroxymethylase domain KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 ALX04_RS10565 2a823d65c836aeee8dc688007ca65360 232 Pfam PF01988 VIT family 22 229 9.1E-44 T 28-03-2018 IPR008217 Ccc1 family ALX04_RS13035 f060b446c1a7519bf83de969b4efcfc4 66 Gene3D G3DSA:2.40.50.140 5 66 0.001 T 28-03-2018 ALX04_RS00760 ace82e0fdeceb71d8105e60e67eacf8f 300 Gene3D G3DSA:3.40.190.10 90 177 1.7E-10 T 28-03-2018 ALX04_RS00760 ace82e0fdeceb71d8105e60e67eacf8f 300 Pfam PF03466 LysR substrate binding domain 89 292 5.2E-27 T 28-03-2018 IPR005119 LysR, substrate-binding ALX04_RS00760 ace82e0fdeceb71d8105e60e67eacf8f 300 Gene3D G3DSA:1.10.10.10 1 89 5.1E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS00760 ace82e0fdeceb71d8105e60e67eacf8f 300 SUPERFAMILY SSF53850 89 293 6.52E-26 T 28-03-2018 ALX04_RS00760 ace82e0fdeceb71d8105e60e67eacf8f 300 SUPERFAMILY SSF46785 1 107 8.19E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS00760 ace82e0fdeceb71d8105e60e67eacf8f 300 Gene3D G3DSA:3.40.190.10 178 266 3.3E-13 T 28-03-2018 ALX04_RS00760 ace82e0fdeceb71d8105e60e67eacf8f 300 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 63 5.7E-13 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 ALX04_RS11370 226264e2a76cc04ea828f22e613805ed 247 Pfam PF04397 LytTr DNA-binding domain 152 243 1.1E-16 T 28-03-2018 IPR007492 LytTR DNA-binding domain GO:0003677 ALX04_RS11370 226264e2a76cc04ea828f22e613805ed 247 SMART SM00448 2 122 1.5E-13 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 ALX04_RS11370 226264e2a76cc04ea828f22e613805ed 247 Pfam PF00072 Response regulator receiver domain 4 115 1.7E-16 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 ALX04_RS11370 226264e2a76cc04ea828f22e613805ed 247 Gene3D G3DSA:3.40.50.2300 1 141 2.5E-15 T 28-03-2018 ALX04_RS11370 226264e2a76cc04ea828f22e613805ed 247 SMART SM00850 150 244 2.0E-17 T 28-03-2018 IPR007492 LytTR DNA-binding domain GO:0003677 ALX04_RS11370 226264e2a76cc04ea828f22e613805ed 247 SUPERFAMILY SSF52172 1 126 3.13E-13 T 28-03-2018 IPR011006 CheY-like superfamily ALX04_RS11370 226264e2a76cc04ea828f22e613805ed 247 Gene3D G3DSA:2.40.50.40 142 210 1.1E-14 T 28-03-2018 ALX04_RS15900 8c0db3a6a37fc85e2d1485b227c07bd1 286 Pfam PF13614 AAA domain 18 200 5.8E-41 T 28-03-2018 IPR025669 AAA domain ALX04_RS15900 8c0db3a6a37fc85e2d1485b227c07bd1 286 SUPERFAMILY SSF52540 17 278 8.28E-37 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase ALX04_RS15900 8c0db3a6a37fc85e2d1485b227c07bd1 286 Gene3D G3DSA:3.40.50.300 2 283 8.8E-37 T 28-03-2018 ALX04_RS10810 933928450d41a58b224a914159a7789a 237 ProSitePatterns PS01183 ubiE/COQ5 methyltransferase family signature 1. 20 35 - T 28-03-2018 IPR023576 UbiE/COQ5 methyltransferase, conserved site GO:0008168 KEGG: 00130+2.1.1.163|KEGG: 00564+2.1.1.16|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895 ALX04_RS10810 933928450d41a58b224a914159a7789a 237 TIGRFAM TIGR01934 MenG_MenH_UbiE: ubiquinone/menaquinone biosynthesis methyltransferase 9 234 9.1E-80 T 28-03-2018 IPR004033 UbiE/COQ5 methyltransferase GO:0008168 KEGG: 00130+2.1.1.163|KEGG: 00564+2.1.1.16|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|Reactome: R-HSA-2142789 ALX04_RS10810 933928450d41a58b224a914159a7789a 237 Gene3D G3DSA:3.40.50.150 5 235 1.3E-47 T 28-03-2018 ALX04_RS10810 933928450d41a58b224a914159a7789a 237 ProSitePatterns PS01184 ubiE/COQ5 methyltransferase family signature 2. 142 156 - T 28-03-2018 IPR023576 UbiE/COQ5 methyltransferase, conserved site GO:0008168 KEGG: 00130+2.1.1.163|KEGG: 00564+2.1.1.16|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895 ALX04_RS10810 933928450d41a58b224a914159a7789a 237 SUPERFAMILY SSF53335 6 228 2.15E-52 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase ALX04_RS10810 933928450d41a58b224a914159a7789a 237 Pfam PF01209 ubiE/COQ5 methyltransferase family 8 234 3.7E-82 T 28-03-2018 IPR004033 UbiE/COQ5 methyltransferase GO:0008168 KEGG: 00130+2.1.1.163|KEGG: 00564+2.1.1.16|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|Reactome: R-HSA-2142789 ALX04_RS10810 933928450d41a58b224a914159a7789a 237 Hamap MF_01813 Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE [ubiE]. 2 234 36.514 T 28-03-2018 IPR004033 UbiE/COQ5 methyltransferase GO:0008168 KEGG: 00130+2.1.1.163|KEGG: 00564+2.1.1.16|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|Reactome: R-HSA-2142789 ALX04_RS00465 fe4f955339f03bb06dee5d77d7b040dc 166 Gene3D G3DSA:3.30.160.20 10 72 1.5E-28 T 28-03-2018 ALX04_RS00465 fe4f955339f03bb06dee5d77d7b040dc 166 TIGRFAM TIGR01021 rpsE_bact: ribosomal protein uS5 10 161 5.1E-64 T 28-03-2018 IPR005712 Ribosomal protein S5, bacterial-type GO:0003735|GO:0006412|GO:0015935 ALX04_RS00465 fe4f955339f03bb06dee5d77d7b040dc 166 SUPERFAMILY SSF54768 9 76 3.77E-24 T 28-03-2018 ALX04_RS00465 fe4f955339f03bb06dee5d77d7b040dc 166 Gene3D G3DSA:3.30.230.10 76 166 3.7E-28 T 28-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup ALX04_RS00465 fe4f955339f03bb06dee5d77d7b040dc 166 Pfam PF03719 Ribosomal protein S5, C-terminal domain 87 157 1.8E-28 T 28-03-2018 IPR005324 Ribosomal protein S5, C-terminal GO:0003735|GO:0005840|GO:0006412 ALX04_RS00465 fe4f955339f03bb06dee5d77d7b040dc 166 SUPERFAMILY SSF54211 80 158 5.31E-25 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold ALX04_RS00465 fe4f955339f03bb06dee5d77d7b040dc 166 Pfam PF00333 Ribosomal protein S5, N-terminal domain 11 75 6.9E-30 T 28-03-2018 IPR013810 Ribosomal protein S5, N-terminal GO:0003723|GO:0003735|GO:0005840|GO:0006412 ALX04_RS00465 fe4f955339f03bb06dee5d77d7b040dc 166 Hamap MF_01307_B 30S ribosomal protein S5 [rpsE]. 1 163 34.149 T 28-03-2018 IPR005712 Ribosomal protein S5, bacterial-type GO:0003735|GO:0006412|GO:0015935 ALX04_RS00465 fe4f955339f03bb06dee5d77d7b040dc 166 ProSitePatterns PS00585 Ribosomal protein S5 signature. 28 60 - T 28-03-2018 IPR018192 Ribosomal protein S5, N-terminal, conserved site ALX04_RS03015 3f19dc9b5e39defb80770dfefa145601 328 Pfam PF12833 Helix-turn-helix domain 243 321 7.4E-15 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 ALX04_RS03015 3f19dc9b5e39defb80770dfefa145601 328 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 303 319 3.2E-5 T 28-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 ALX04_RS03015 3f19dc9b5e39defb80770dfefa145601 328 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 288 303 3.2E-5 T 28-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 ALX04_RS03015 3f19dc9b5e39defb80770dfefa145601 328 Gene3D G3DSA:1.10.10.60 264 322 1.4E-11 T 28-03-2018 ALX04_RS03015 3f19dc9b5e39defb80770dfefa145601 328 SUPERFAMILY SSF46689 273 322 1.84E-11 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 ALX04_RS03015 3f19dc9b5e39defb80770dfefa145601 328 Gene3D G3DSA:1.10.10.60 205 261 2.3E-4 T 28-03-2018 ALX04_RS03015 3f19dc9b5e39defb80770dfefa145601 328 SMART SM00342 237 319 3.6E-21 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 ALX04_RS09445 8f0c03c58d729c3c3526fcc921716541 94 Pfam PF04994 TfoX C-terminal domain 14 88 1.7E-19 T 28-03-2018 IPR007077 TfoX, C-terminal ALX04_RS09445 8f0c03c58d729c3c3526fcc921716541 94 Gene3D G3DSA:1.10.150.20 12 90 2.3E-18 T 28-03-2018 ALX04_RS10200 6a1ceb6ef6f6bdd88410eb23a5ca3ca4 261 Gene3D G3DSA:3.90.190.10 21 202 1.0E-16 T 28-03-2018 IPR029021 Protein-tyrosine phosphatase-like ALX04_RS10200 6a1ceb6ef6f6bdd88410eb23a5ca3ca4 261 ProSitePatterns PS00383 Tyrosine specific protein phosphatases active site. 149 159 - T 28-03-2018 IPR016130 Protein-tyrosine phosphatase, active site GO:0004725|GO:0016311 ALX04_RS10200 6a1ceb6ef6f6bdd88410eb23a5ca3ca4 261 SUPERFAMILY SSF52799 8 259 4.63E-47 T 28-03-2018 IPR029021 Protein-tyrosine phosphatase-like ALX04_RS10200 6a1ceb6ef6f6bdd88410eb23a5ca3ca4 261 Pfam PF13350 Tyrosine phosphatase family 8 259 1.6E-56 T 28-03-2018 IPR026893 Tyrosine/serine-protein phosphatase IphP-type ALX04_RS10830 2d9eed0902a4ef776aa9956098b10f69 250 Gene3D G3DSA:1.20.1080.10 1 250 2.9E-74 T 28-03-2018 IPR023271 Aquaporin-like Reactome: R-HSA-432047 ALX04_RS10830 2d9eed0902a4ef776aa9956098b10f69 250 Pfam PF00230 Major intrinsic protein 9 244 4.5E-44 T 28-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 ALX04_RS10830 2d9eed0902a4ef776aa9956098b10f69 250 SUPERFAMILY SSF81338 7 249 6.41E-67 T 28-03-2018 IPR023271 Aquaporin-like Reactome: R-HSA-432047 ALX04_RS10830 2d9eed0902a4ef776aa9956098b10f69 250 PRINTS PR00783 Major intrinsic protein family signature 227 247 5.5E-40 T 28-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 ALX04_RS10830 2d9eed0902a4ef776aa9956098b10f69 250 PRINTS PR00783 Major intrinsic protein family signature 147 165 5.5E-40 T 28-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 ALX04_RS10830 2d9eed0902a4ef776aa9956098b10f69 250 PRINTS PR00783 Major intrinsic protein family signature 55 79 5.5E-40 T 28-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 ALX04_RS10830 2d9eed0902a4ef776aa9956098b10f69 250 PRINTS PR00783 Major intrinsic protein family signature 7 26 5.5E-40 T 28-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 ALX04_RS10830 2d9eed0902a4ef776aa9956098b10f69 250 PRINTS PR00783 Major intrinsic protein family signature 92 111 5.5E-40 T 28-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 ALX04_RS10830 2d9eed0902a4ef776aa9956098b10f69 250 PRINTS PR00783 Major intrinsic protein family signature 180 202 5.5E-40 T 28-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 ALX04_RS05815 cd5883f593e0da55b2fe15191d85742a 194 Pfam PF00160 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD 17 190 5.6E-51 T 28-03-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 ALX04_RS05815 cd5883f593e0da55b2fe15191d85742a 194 Gene3D G3DSA:2.40.100.10 5 194 4.7E-69 T 28-03-2018 IPR029000 Cyclophilin-like domain ALX04_RS05815 cd5883f593e0da55b2fe15191d85742a 194 PIRSF PIRSF001467 141 194 2.3E-11 T 28-03-2018 IPR024936 Cyclophilin-type peptidyl-prolyl cis-trans isomerase GO:0003755 ALX04_RS05815 cd5883f593e0da55b2fe15191d85742a 194 PIRSF PIRSF001467 8 124 3.0E-44 T 28-03-2018 IPR024936 Cyclophilin-type peptidyl-prolyl cis-trans isomerase GO:0003755 ALX04_RS05815 cd5883f593e0da55b2fe15191d85742a 194 SUPERFAMILY SSF50891 145 192 4.24E-62 T 28-03-2018 IPR029000 Cyclophilin-like domain ALX04_RS05815 cd5883f593e0da55b2fe15191d85742a 194 SUPERFAMILY SSF50891 14 117 4.24E-62 T 28-03-2018 IPR029000 Cyclophilin-like domain ALX04_RS05815 cd5883f593e0da55b2fe15191d85742a 194 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 55 67 2.3E-20 T 28-03-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 ALX04_RS05815 cd5883f593e0da55b2fe15191d85742a 194 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 97 112 2.3E-20 T 28-03-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 ALX04_RS05815 cd5883f593e0da55b2fe15191d85742a 194 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 29 44 2.3E-20 T 28-03-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 ALX04_RS09450 f013faf50ac900381c7d1ef0c3a34888 422 Pfam PF14501 GHKL domain 321 420 4.9E-10 T 28-03-2018 IPR032834 Sensor histidine kinase NatK, C-terminal domain ALX04_RS09450 f013faf50ac900381c7d1ef0c3a34888 422 Gene3D G3DSA:1.10.287.130 210 267 5.4E-5 T 28-03-2018 ALX04_RS09450 f013faf50ac900381c7d1ef0c3a34888 422 Gene3D G3DSA:3.30.565.10 285 403 2.9E-9 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain ALX04_RS09450 f013faf50ac900381c7d1ef0c3a34888 422 SUPERFAMILY SSF55874 294 398 2.33E-9 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain ALX04_RS03360 e30171872c66ef4a45f57a82abfa9b9c 223 SUPERFAMILY SSF161098 14 209 7.06E-37 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 ALX04_RS03360 e30171872c66ef4a45f57a82abfa9b9c 223 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 57 219 4.6E-15 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 ALX04_RS03360 e30171872c66ef4a45f57a82abfa9b9c 223 Gene3D G3DSA:1.10.3720.10 9 223 3.2E-30 T 28-03-2018 ALX04_RS05940 de600ede32dd7c4c6cac4aedefe587d5 138 Pfam PF06103 Bacterial protein of unknown function (DUF948) 5 92 1.1E-31 T 28-03-2018 IPR009293 Uncharacterised protein family UPF0478 ALX04_RS05940 de600ede32dd7c4c6cac4aedefe587d5 138 Gene3D G3DSA:3.90.20.10 11 138 3.2E-6 T 28-03-2018 ALX04_RS12890 4f819eeefe20c222d1632e1609a25a19 239 Pfam PF02517 CAAX protease self-immunity 102 197 6.9E-12 T 28-03-2018 IPR003675 CAAX amino terminal protease GO:0016020 Reactome: R-HSA-5689880 ALX04_RS04430 0f8ef2a0ee7ee75abf59b7e3518b383e 280 PIRSF PIRSF006221 1 280 4.7E-96 T 28-03-2018 IPR016477 Fructosamine/Ketosamine-3-kinase Reactome: R-HSA-163841 ALX04_RS04430 0f8ef2a0ee7ee75abf59b7e3518b383e 280 Pfam PF03881 Fructosamine kinase 14 279 2.0E-85 T 28-03-2018 IPR016477 Fructosamine/Ketosamine-3-kinase Reactome: R-HSA-163841 ALX04_RS04430 0f8ef2a0ee7ee75abf59b7e3518b383e 280 Gene3D G3DSA:3.30.200.20 1 87 9.2E-18 T 28-03-2018 ALX04_RS04430 0f8ef2a0ee7ee75abf59b7e3518b383e 280 SUPERFAMILY SSF56112 6 277 5.24E-47 T 28-03-2018 IPR011009 Protein kinase-like domain ALX04_RS04430 0f8ef2a0ee7ee75abf59b7e3518b383e 280 Gene3D G3DSA:3.90.1200.10 95 262 6.6E-18 T 28-03-2018 ALX04_RS14585 f7730852859deff75b31a792a1333456 224 Gene3D G3DSA:1.20.58.220 1 111 1.3E-25 T 28-03-2018 ALX04_RS14585 f7730852859deff75b31a792a1333456 224 SUPERFAMILY SSF109755 2 218 4.92E-61 T 28-03-2018 ALX04_RS14585 f7730852859deff75b31a792a1333456 224 PIRSF PIRSF003107 1 218 9.5E-61 T 28-03-2018 IPR028366 Phosphate transport system protein PhoU GO:0005737|GO:0030643|GO:0045936 ALX04_RS14585 f7730852859deff75b31a792a1333456 224 Pfam PF01895 PhoU domain 17 103 1.9E-21 T 28-03-2018 IPR026022 PhoU domain ALX04_RS14585 f7730852859deff75b31a792a1333456 224 Pfam PF01895 PhoU domain 120 205 2.0E-14 T 28-03-2018 IPR026022 PhoU domain ALX04_RS14585 f7730852859deff75b31a792a1333456 224 Gene3D G3DSA:1.20.58.220 112 224 3.2E-21 T 28-03-2018 ALX04_RS14585 f7730852859deff75b31a792a1333456 224 TIGRFAM TIGR02135 phoU_full: phosphate transport system regulatory protein PhoU 5 214 6.5E-64 T 28-03-2018 IPR028366 Phosphate transport system protein PhoU GO:0005737|GO:0030643|GO:0045936 ALX04_RS13575 73772d2f06e1bb7383d174aa17119bd8 460 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 403 431 - T 28-03-2018 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 ALX04_RS13575 73772d2f06e1bb7383d174aa17119bd8 460 Pfam PF00483 Nucleotidyl transferase 6 220 8.9E-22 T 28-03-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 ALX04_RS13575 73772d2f06e1bb7383d174aa17119bd8 460 Hamap MF_01631 Bifunctional protein GlmU [glmU]. 3 452 40.543 T 28-03-2018 IPR005882 Bifunctional UDP-N-acetylglucosamine pyrophosphorylase/glucosamine-1-phosphate N-acetyltransferase GO:0000287|GO:0000902|GO:0003977|GO:0005737|GO:0009103|GO:0009252|GO:0019134 KEGG: 00520+2.3.1.157+2.7.7.23|KEGG: 00561+2.3.1.15|KEGG: 00564+2.3.1.15|MetaCyc: PWY-5514|MetaCyc: PWY-5667|MetaCyc: PWY-6453|MetaCyc: PWY-7411|MetaCyc: PWY-7587 ALX04_RS13575 73772d2f06e1bb7383d174aa17119bd8 460 SUPERFAMILY SSF53448 5 253 7.21E-64 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases ALX04_RS13575 73772d2f06e1bb7383d174aa17119bd8 460 TIGRFAM TIGR01173 glmU: UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase 5 448 1.3E-173 T 28-03-2018 IPR005882 Bifunctional UDP-N-acetylglucosamine pyrophosphorylase/glucosamine-1-phosphate N-acetyltransferase GO:0000287|GO:0000902|GO:0003977|GO:0005737|GO:0009103|GO:0009252|GO:0019134 KEGG: 00520+2.3.1.157+2.7.7.23|KEGG: 00561+2.3.1.15|KEGG: 00564+2.3.1.15|MetaCyc: PWY-5514|MetaCyc: PWY-5667|MetaCyc: PWY-6453|MetaCyc: PWY-7411|MetaCyc: PWY-7587 ALX04_RS13575 73772d2f06e1bb7383d174aa17119bd8 460 Gene3D G3DSA:2.160.10.10 246 307 5.7E-17 T 28-03-2018 ALX04_RS13575 73772d2f06e1bb7383d174aa17119bd8 460 Gene3D G3DSA:2.160.10.10 308 440 1.3E-31 T 28-03-2018 ALX04_RS13575 73772d2f06e1bb7383d174aa17119bd8 460 SUPERFAMILY SSF51161 255 432 1.05E-43 T 28-03-2018 IPR011004 Trimeric LpxA-like ALX04_RS13575 73772d2f06e1bb7383d174aa17119bd8 460 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 266 300 6.2E-8 T 28-03-2018 IPR001451 Hexapeptide repeat ALX04_RS13575 73772d2f06e1bb7383d174aa17119bd8 460 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 318 351 1.3E-5 T 28-03-2018 IPR001451 Hexapeptide repeat ALX04_RS13575 73772d2f06e1bb7383d174aa17119bd8 460 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 394 428 2.4E-6 T 28-03-2018 IPR001451 Hexapeptide repeat ALX04_RS13575 73772d2f06e1bb7383d174aa17119bd8 460 Gene3D G3DSA:3.90.550.10 3 245 4.1E-62 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases ALX04_RS08865 163f883ac58ef45589d5f9f638435b09 833 TIGRFAM TIGR03715 KxYKxGKxW: KxYKxGKxW signal peptide 6 27 7.0E-7 T 28-03-2018 IPR022263 KxYKxGKxW signal peptide ALX04_RS08865 163f883ac58ef45589d5f9f638435b09 833 TIGRFAM TIGR01167 LPXTG_anchor: LPXTG cell wall anchor domain 797 832 5.6E-4 T 28-03-2018 ALX04_RS11580 1938cca6180b91a0945ee93dc8f03897 77 SUPERFAMILY SSF55174 4 67 9.68E-20 T 28-03-2018 ALX04_RS11580 1938cca6180b91a0945ee93dc8f03897 77 TIGRFAM TIGR02988 YaaA_near_RecF: S4 domain protein YaaA 5 63 4.0E-30 T 28-03-2018 IPR014330 RNA-binding S4-related,YaaA ALX04_RS11580 1938cca6180b91a0945ee93dc8f03897 77 Pfam PF13275 S4 domain 5 66 1.8E-26 T 28-03-2018 ALX04_RS11580 1938cca6180b91a0945ee93dc8f03897 77 Gene3D G3DSA:3.10.290.10 2 70 2.1E-11 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 ALX04_RS01030 c3d0781d4100be20ab9123ee933d3ebf 323 SUPERFAMILY SSF53448 1 287 4.78E-23 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases ALX04_RS01030 c3d0781d4100be20ab9123ee933d3ebf 323 Pfam PF00535 Glycosyl transferase family 2 6 155 5.6E-9 T 28-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 ALX04_RS01030 c3d0781d4100be20ab9123ee933d3ebf 323 Gene3D G3DSA:3.90.550.10 4 238 2.1E-17 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases ALX04_RS10510 4a04153813bf90ea0a7397495a5e22af 124 Pfam PF04343 Protein of unknown function, DUF488 4 115 2.4E-30 T 28-03-2018 IPR007438 Protein of unknown function DUF488 ALX04_RS04090 dea21334593345bcddf808bbe37f9f40 464 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 13 416 3.7E-72 T 28-03-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 ALX04_RS04090 dea21334593345bcddf808bbe37f9f40 464 Gene3D G3DSA:1.20.1250.20 250 460 5.9E-20 T 28-03-2018 ALX04_RS04090 dea21334593345bcddf808bbe37f9f40 464 Gene3D G3DSA:1.20.1250.20 6 194 4.2E-30 T 28-03-2018 ALX04_RS04090 dea21334593345bcddf808bbe37f9f40 464 PRINTS PR01036 Tetracycline resistance protein TetB signature 106 126 1.0E-9 T 28-03-2018 ALX04_RS04090 dea21334593345bcddf808bbe37f9f40 464 PRINTS PR01036 Tetracycline resistance protein TetB signature 15 39 1.0E-9 T 28-03-2018 ALX04_RS04090 dea21334593345bcddf808bbe37f9f40 464 PRINTS PR01036 Tetracycline resistance protein TetB signature 300 324 1.0E-9 T 28-03-2018 ALX04_RS04090 dea21334593345bcddf808bbe37f9f40 464 PRINTS PR01036 Tetracycline resistance protein TetB signature 136 160 1.0E-9 T 28-03-2018 ALX04_RS04090 dea21334593345bcddf808bbe37f9f40 464 SUPERFAMILY SSF103473 8 191 6.67E-52 T 28-03-2018 IPR020846 Major facilitator superfamily domain ALX04_RS04090 dea21334593345bcddf808bbe37f9f40 464 SUPERFAMILY SSF103473 246 446 6.67E-52 T 28-03-2018 IPR020846 Major facilitator superfamily domain ALX04_RS04090 dea21334593345bcddf808bbe37f9f40 464 Pfam PF07690 Major Facilitator Superfamily 18 407 2.6E-39 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 ALX04_RS14195 36f73f4c65d536c5908f5f57f7615fbc 225 Gene3D G3DSA:3.40.50.1240 1 225 1.8E-55 T 28-03-2018 IPR029033 Histidine phosphatase superfamily ALX04_RS14195 36f73f4c65d536c5908f5f57f7615fbc 225 TIGRFAM TIGR01258 pgm_1: phosphoglycerate mutase 1 family 3 223 6.0E-79 T 28-03-2018 IPR005952 Phosphoglycerate mutase 1 GO:0004619|GO:0006096|GO:0016868 KEGG: 00010+5.4.2.11|KEGG: 00260+5.4.2.11|KEGG: 00680+5.4.2.11|MetaCyc: PWY-1622|MetaCyc: PWY-5484 ALX04_RS14195 36f73f4c65d536c5908f5f57f7615fbc 225 ProSitePatterns PS00175 Phosphoglycerate mutase family phosphohistidine signature. 6 15 - T 28-03-2018 IPR001345 Phosphoglycerate/bisphosphoglycerate mutase, active site GO:0003824|GO:0008152 ALX04_RS14195 36f73f4c65d536c5908f5f57f7615fbc 225 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 4 121 4.1E-26 T 28-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 ALX04_RS14195 36f73f4c65d536c5908f5f57f7615fbc 225 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 140 205 1.1E-5 T 28-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 ALX04_RS14195 36f73f4c65d536c5908f5f57f7615fbc 225 PIRSF PIRSF000709 170 214 10.0 T 28-03-2018 ALX04_RS14195 36f73f4c65d536c5908f5f57f7615fbc 225 PIRSF PIRSF000709 2 105 1.1E-4 T 28-03-2018 ALX04_RS14195 36f73f4c65d536c5908f5f57f7615fbc 225 Hamap MF_01039 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [gpmA]. 1 225 39.145 T 28-03-2018 IPR005952 Phosphoglycerate mutase 1 GO:0004619|GO:0006096|GO:0016868 KEGG: 00010+5.4.2.11|KEGG: 00260+5.4.2.11|KEGG: 00680+5.4.2.11|MetaCyc: PWY-1622|MetaCyc: PWY-5484 ALX04_RS14195 36f73f4c65d536c5908f5f57f7615fbc 225 SMART SM00855 3 186 1.2E-25 T 28-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 ALX04_RS14195 36f73f4c65d536c5908f5f57f7615fbc 225 SUPERFAMILY SSF53254 1 217 8.64E-64 T 28-03-2018 IPR029033 Histidine phosphatase superfamily ALX04_RS01015 0acb2afc48ec67d5b6f8414ad8375b5d 110 SMART SM00530 6 59 9.5E-8 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 ALX04_RS01015 0acb2afc48ec67d5b6f8414ad8375b5d 110 Pfam PF01381 Helix-turn-helix 7 59 1.7E-5 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 ALX04_RS01015 0acb2afc48ec67d5b6f8414ad8375b5d 110 Gene3D G3DSA:1.10.260.40 1 108 1.5E-14 T 28-03-2018 ALX04_RS01015 0acb2afc48ec67d5b6f8414ad8375b5d 110 SUPERFAMILY SSF47413 1 66 1.27E-10 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 ALX04_RS10750 c3fa51c053158279e3ffc35ea18f9058 65 Gene3D G3DSA:1.10.260.40 4 63 3.8E-5 T 28-03-2018 ALX04_RS10750 c3fa51c053158279e3ffc35ea18f9058 65 SUPERFAMILY SSF47413 5 61 5.63E-5 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 ALX04_RS08495 c4c6d808968de1551ec0615d1972e915 132 Gene3D G3DSA:2.60.120.10 11 132 3.2E-31 T 28-03-2018 IPR014710 RmlC-like jelly roll fold ALX04_RS08495 c4c6d808968de1551ec0615d1972e915 132 Pfam PF07883 Cupin domain 45 105 2.6E-10 T 28-03-2018 IPR013096 Cupin 2, conserved barrel ALX04_RS08495 c4c6d808968de1551ec0615d1972e915 132 SUPERFAMILY SSF51182 15 131 4.15E-28 T 28-03-2018 IPR011051 RmlC-like cupin domain ALX04_RS08255 7f1b26329b012fd37d1bc9814aa81788 288 PRINTS PR00069 Aldo-keto reductase signature 196 220 1.1E-42 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 ALX04_RS08255 7f1b26329b012fd37d1bc9814aa81788 288 PRINTS PR00069 Aldo-keto reductase signature 94 112 1.1E-42 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 ALX04_RS08255 7f1b26329b012fd37d1bc9814aa81788 288 PRINTS PR00069 Aldo-keto reductase signature 38 62 1.1E-42 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 ALX04_RS08255 7f1b26329b012fd37d1bc9814aa81788 288 PRINTS PR00069 Aldo-keto reductase signature 123 140 1.1E-42 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 ALX04_RS08255 7f1b26329b012fd37d1bc9814aa81788 288 PRINTS PR00069 Aldo-keto reductase signature 157 186 1.1E-42 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 ALX04_RS08255 7f1b26329b012fd37d1bc9814aa81788 288 Pfam PF00248 Aldo/keto reductase family 18 260 3.4E-38 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain ALX04_RS08255 7f1b26329b012fd37d1bc9814aa81788 288 SUPERFAMILY SSF51430 6 272 1.02E-80 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain ALX04_RS08255 7f1b26329b012fd37d1bc9814aa81788 288 Gene3D G3DSA:3.20.20.100 1 275 2.8E-83 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain ALX04_RS08255 7f1b26329b012fd37d1bc9814aa81788 288 ProSitePatterns PS00798 Aldo/keto reductase family signature 1. 42 59 - T 28-03-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 ALX04_RS08255 7f1b26329b012fd37d1bc9814aa81788 288 PIRSF PIRSF000097 1 280 1.4E-77 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 ALX04_RS04140 7aa235291d1429d412587c2874b26e54 183 Gene3D G3DSA:1.10.10.60 7 47 2.0E-10 T 28-03-2018 ALX04_RS04140 7aa235291d1429d412587c2874b26e54 183 Gene3D G3DSA:1.10.10.60 48 136 4.3E-4 T 28-03-2018 ALX04_RS04140 7aa235291d1429d412587c2874b26e54 183 SUPERFAMILY SSF46689 4 70 5.34E-13 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 ALX04_RS04140 7aa235291d1429d412587c2874b26e54 183 Pfam PF00440 Bacterial regulatory proteins, tetR family 19 59 3.0E-6 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 ALX04_RS04770 d6156aea848a800c00ff91cb8d353e71 390 Pfam PF01476 LysM domain 347 389 3.3E-12 T 28-03-2018 IPR018392 LysM domain ALX04_RS04770 d6156aea848a800c00ff91cb8d353e71 390 SUPERFAMILY SSF54106 344 389 9.81E-11 T 28-03-2018 IPR018392 LysM domain ALX04_RS04770 d6156aea848a800c00ff91cb8d353e71 390 SMART SM00641 119 237 3.8E-30 T 28-03-2018 IPR018077 Glycoside hydrolase, family 25 subgroup ALX04_RS04770 d6156aea848a800c00ff91cb8d353e71 390 SMART SM00257 346 390 1.6E-14 T 28-03-2018 IPR018392 LysM domain ALX04_RS04770 d6156aea848a800c00ff91cb8d353e71 390 Gene3D G3DSA:2.30.30.410 235 342 1.2E-7 T 28-03-2018 ALX04_RS04770 d6156aea848a800c00ff91cb8d353e71 390 Pfam PF01183 Glycosyl hydrolases family 25 37 220 2.0E-25 T 28-03-2018 IPR002053 Glycoside hydrolase, family 25 GO:0003796|GO:0009253|GO:0016998 ALX04_RS04770 d6156aea848a800c00ff91cb8d353e71 390 Pfam PF08460 Bacterial SH3 domain 264 324 2.3E-6 T 28-03-2018 IPR003646 SH3-like domain, bacterial-type ALX04_RS04770 d6156aea848a800c00ff91cb8d353e71 390 Gene3D G3DSA:3.20.20.80 32 228 1.1E-29 T 28-03-2018 ALX04_RS04770 d6156aea848a800c00ff91cb8d353e71 390 Gene3D G3DSA:3.10.350.10 343 390 2.4E-13 T 28-03-2018 ALX04_RS04770 d6156aea848a800c00ff91cb8d353e71 390 SUPERFAMILY SSF51445 34 231 7.02E-30 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily ALX04_RS02595 663e89cb51c89243dbf2cc67dfd32ace 73 Pfam PF06014 Bacterial protein of unknown function (DUF910) 1 61 8.3E-32 T 28-03-2018 IPR009256 Protein of unknown function DUF910 ALX04_RS02595 663e89cb51c89243dbf2cc67dfd32ace 73 Gene3D G3DSA:1.10.287.760 1 65 6.1E-32 T 28-03-2018 IPR023164 YqgQ-like domain ALX04_RS02595 663e89cb51c89243dbf2cc67dfd32ace 73 SUPERFAMILY SSF158379 1 62 5.23E-26 T 28-03-2018 IPR023164 YqgQ-like domain ALX04_RS10165 101b6569847550d1305a5a4a3cd4cf8d 313 SUPERFAMILY SSF53474 71 199 1.19E-40 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold ALX04_RS10165 101b6569847550d1305a5a4a3cd4cf8d 313 SUPERFAMILY SSF53474 238 311 1.19E-40 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold ALX04_RS10165 101b6569847550d1305a5a4a3cd4cf8d 313 Pfam PF12146 Serine aminopeptidase, S33 90 200 2.1E-12 T 28-03-2018 IPR022742 Serine aminopeptidase, S33 ALX04_RS10165 101b6569847550d1305a5a4a3cd4cf8d 313 Gene3D G3DSA:3.40.50.1820 40 313 4.5E-37 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold ALX04_RS12725 6a2854b76a319d5003c744bfcc347f43 134 Gene3D G3DSA:3.40.50.620 1 131 6.4E-29 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold ALX04_RS12725 6a2854b76a319d5003c744bfcc347f43 134 Pfam PF01467 Cytidylyltransferase-like 5 127 1.0E-21 T 28-03-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 ALX04_RS12725 6a2854b76a319d5003c744bfcc347f43 134 SUPERFAMILY SSF52374 1 127 7.93E-33 T 28-03-2018 ALX04_RS12725 6a2854b76a319d5003c744bfcc347f43 134 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 3 68 3.3E-21 T 28-03-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 ALX04_RS12725 6a2854b76a319d5003c744bfcc347f43 134 TIGRFAM TIGR01518 g3p_cytidyltrns: glycerol-3-phosphate cytidylyltransferase 4 129 1.6E-63 T 28-03-2018 IPR006409 Glycerol-3-phosphate cytidylyltransferase GO:0005737|GO:0019350|GO:0046872|GO:0047348 ALX04_RS02410 955b807a579949735c951220bd1acb76 211 Pfam PF01467 Cytidylyltransferase-like 26 181 4.6E-34 T 28-03-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 ALX04_RS02410 955b807a579949735c951220bd1acb76 211 Hamap MF_00244 Probable nicotinate-nucleotide adenylyltransferase [nadD]. 22 208 30.932 T 28-03-2018 IPR005248 Nicotinate/nicotinamide nucleotide adenylyltransferase GO:0009435|GO:0016779 KEGG: 00760+2.7.7.18|MetaCyc: PWY-5381|MetaCyc: PWY-5653|MetaCyc: PWY-7761|Reactome: R-HSA-196807 ALX04_RS02410 955b807a579949735c951220bd1acb76 211 TIGRFAM TIGR00482 TIGR00482: nicotinate (nicotinamide) nucleotide adenylyltransferase 26 207 1.4E-55 T 28-03-2018 IPR005248 Nicotinate/nicotinamide nucleotide adenylyltransferase GO:0009435|GO:0016779 KEGG: 00760+2.7.7.18|MetaCyc: PWY-5381|MetaCyc: PWY-5653|MetaCyc: PWY-7761|Reactome: R-HSA-196807 ALX04_RS02410 955b807a579949735c951220bd1acb76 211 SUPERFAMILY SSF52374 21 207 2.47E-55 T 28-03-2018 ALX04_RS02410 955b807a579949735c951220bd1acb76 211 Gene3D G3DSA:3.40.50.620 18 208 8.3E-54 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold ALX04_RS09505 bcc529c2bc29e0add50b7836d6379ff5 915 Gene3D G3DSA:3.10.20.320 702 773 3.6E-14 T 28-03-2018 ALX04_RS09505 bcc529c2bc29e0add50b7836d6379ff5 915 SUPERFAMILY SSF52047 366 626 1.33E-9 T 28-03-2018 ALX04_RS09505 bcc529c2bc29e0add50b7836d6379ff5 915 Pfam PF03382 Mycoplasma protein of unknown function, DUF285 450 564 1.6E-23 T 28-03-2018 IPR005046 Protein of unknown function DUF285 ALX04_RS09505 bcc529c2bc29e0add50b7836d6379ff5 915 Pfam PF03382 Mycoplasma protein of unknown function, DUF285 190 306 2.3E-17 T 28-03-2018 IPR005046 Protein of unknown function DUF285 ALX04_RS09505 bcc529c2bc29e0add50b7836d6379ff5 915 Pfam PF06458 MucBP domain 709 770 1.2E-11 T 28-03-2018 IPR009459 MucBP domain ALX04_RS09505 bcc529c2bc29e0add50b7836d6379ff5 915 Gene3D G3DSA:3.80.10.10 536 664 1.4E-4 T 28-03-2018 IPR032675 Leucine-rich repeat domain, L domain-like ALX04_RS09505 bcc529c2bc29e0add50b7836d6379ff5 915 TIGRFAM TIGR02167 Liste_lipo_26: bacterial surface protein 26-residue repeat 455 480 1.2E-9 T 28-03-2018 IPR011889 Bacterial surface protein 26-residue repeat ALX04_RS09505 bcc529c2bc29e0add50b7836d6379ff5 915 TIGRFAM TIGR02167 Liste_lipo_26: bacterial surface protein 26-residue repeat 273 297 5.0E-9 T 28-03-2018 IPR011889 Bacterial surface protein 26-residue repeat ALX04_RS09505 bcc529c2bc29e0add50b7836d6379ff5 915 TIGRFAM TIGR02167 Liste_lipo_26: bacterial surface protein 26-residue repeat 351 374 5.8E-7 T 28-03-2018 IPR011889 Bacterial surface protein 26-residue repeat ALX04_RS09505 bcc529c2bc29e0add50b7836d6379ff5 915 TIGRFAM TIGR02167 Liste_lipo_26: bacterial surface protein 26-residue repeat 507 531 6.3E-7 T 28-03-2018 IPR011889 Bacterial surface protein 26-residue repeat ALX04_RS09505 bcc529c2bc29e0add50b7836d6379ff5 915 TIGRFAM TIGR02167 Liste_lipo_26: bacterial surface protein 26-residue repeat 403 423 1.2E-5 T 28-03-2018 IPR011889 Bacterial surface protein 26-residue repeat ALX04_RS09505 bcc529c2bc29e0add50b7836d6379ff5 915 TIGRFAM TIGR02167 Liste_lipo_26: bacterial surface protein 26-residue repeat 221 245 1.8E-7 T 28-03-2018 IPR011889 Bacterial surface protein 26-residue repeat ALX04_RS09505 bcc529c2bc29e0add50b7836d6379ff5 915 TIGRFAM TIGR02167 Liste_lipo_26: bacterial surface protein 26-residue repeat 299 323 7.0E-11 T 28-03-2018 IPR011889 Bacterial surface protein 26-residue repeat ALX04_RS09505 bcc529c2bc29e0add50b7836d6379ff5 915 TIGRFAM TIGR02167 Liste_lipo_26: bacterial surface protein 26-residue repeat 481 506 3.0E-9 T 28-03-2018 IPR011889 Bacterial surface protein 26-residue repeat ALX04_RS09505 bcc529c2bc29e0add50b7836d6379ff5 915 TIGRFAM TIGR02167 Liste_lipo_26: bacterial surface protein 26-residue repeat 429 453 1.2E-5 T 28-03-2018 IPR011889 Bacterial surface protein 26-residue repeat ALX04_RS09505 bcc529c2bc29e0add50b7836d6379ff5 915 TIGRFAM TIGR02167 Liste_lipo_26: bacterial surface protein 26-residue repeat 535 557 7.9E-4 T 28-03-2018 IPR011889 Bacterial surface protein 26-residue repeat ALX04_RS09505 bcc529c2bc29e0add50b7836d6379ff5 915 TIGRFAM TIGR02167 Liste_lipo_26: bacterial surface protein 26-residue repeat 326 349 4.0E-5 T 28-03-2018 IPR011889 Bacterial surface protein 26-residue repeat ALX04_RS09505 bcc529c2bc29e0add50b7836d6379ff5 915 TIGRFAM TIGR02167 Liste_lipo_26: bacterial surface protein 26-residue repeat 378 398 4.2E-5 T 28-03-2018 IPR011889 Bacterial surface protein 26-residue repeat ALX04_RS09505 bcc529c2bc29e0add50b7836d6379ff5 915 TIGRFAM TIGR02167 Liste_lipo_26: bacterial surface protein 26-residue repeat 247 265 6.8E-5 T 28-03-2018 IPR011889 Bacterial surface protein 26-residue repeat ALX04_RS09505 bcc529c2bc29e0add50b7836d6379ff5 915 TIGRFAM TIGR02167 Liste_lipo_26: bacterial surface protein 26-residue repeat 559 583 3.3E-9 T 28-03-2018 IPR011889 Bacterial surface protein 26-residue repeat ALX04_RS09505 bcc529c2bc29e0add50b7836d6379ff5 915 SUPERFAMILY SSF52058 191 469 5.1E-20 T 28-03-2018 IPR032675 Leucine-rich repeat domain, L domain-like ALX04_RS09505 bcc529c2bc29e0add50b7836d6379ff5 915 Gene3D G3DSA:3.80.10.10 172 535 2.2E-23 T 28-03-2018 IPR032675 Leucine-rich repeat domain, L domain-like ALX04_RS02540 16bb07442c76d5567583e1fabdd910c2 160 SUPERFAMILY SSF46557 5 79 6.67E-25 T 28-03-2018 IPR022691 Transcription elongation factor, GreA/GreB, N-terminal GO:0003677|GO:0032784 ALX04_RS02540 16bb07442c76d5567583e1fabdd910c2 160 Pfam PF03449 Transcription elongation factor, N-terminal 8 77 2.9E-26 T 28-03-2018 IPR022691 Transcription elongation factor, GreA/GreB, N-terminal GO:0003677|GO:0032784 ALX04_RS02540 16bb07442c76d5567583e1fabdd910c2 160 PIRSF PIRSF006092 1 160 3.0E-48 T 28-03-2018 IPR023459 Transcription elongation factor GreA/GreB family GO:0070063 ALX04_RS02540 16bb07442c76d5567583e1fabdd910c2 160 Gene3D G3DSA:3.10.50.30 80 159 1.5E-24 T 28-03-2018 IPR001437 Transcription elongation factor, GreA/GreB, C-terminal GO:0003677|GO:0032784 ALX04_RS02540 16bb07442c76d5567583e1fabdd910c2 160 Hamap MF_00105 Transcription elongation factor GreA [greA]. 5 158 30.667 T 28-03-2018 IPR028624 Transcription elongation factor GreA/GreB GO:0003677|GO:0032784|GO:0070063 ALX04_RS02540 16bb07442c76d5567583e1fabdd910c2 160 SUPERFAMILY SSF54534 83 158 2.35E-19 T 28-03-2018 ALX04_RS02540 16bb07442c76d5567583e1fabdd910c2 160 Gene3D G3DSA:1.10.287.180 6 79 1.2E-27 T 28-03-2018 ALX04_RS02540 16bb07442c76d5567583e1fabdd910c2 160 TIGRFAM TIGR01462 greA: transcription elongation factor GreA 8 158 4.6E-53 T 28-03-2018 IPR006359 Transcription elongation factor GreA GO:0003677|GO:0032784 ALX04_RS02540 16bb07442c76d5567583e1fabdd910c2 160 Pfam PF01272 Transcription elongation factor, GreA/GreB, C-term 85 158 1.6E-23 T 28-03-2018 IPR001437 Transcription elongation factor, GreA/GreB, C-terminal GO:0003677|GO:0032784 ALX04_RS02540 16bb07442c76d5567583e1fabdd910c2 160 ProSitePatterns PS00829 Prokaryotic transcription elongation factors signature 1. 20 51 - T 28-03-2018 IPR018151 Transcription elongation factor, GreA/GreB, conserved site GO:0003677|GO:0032784 ALX04_RS02540 16bb07442c76d5567583e1fabdd910c2 160 ProSitePatterns PS00830 Prokaryotic transcription elongation factors signature 2. 123 139 - T 28-03-2018 IPR018151 Transcription elongation factor, GreA/GreB, conserved site GO:0003677|GO:0032784 ALX04_RS07315 09a342ddfc76b0081f36e181eae564d1 383 Hamap MF_00125 ATP phosphoribosyltransferase regulatory subunit [hisZ]. 16 365 33.493 T 28-03-2018 IPR004517 ATP phosphoribosyltransferase regulatory subunit GO:0000105|GO:0005737 ALX04_RS07315 09a342ddfc76b0081f36e181eae564d1 383 PIRSF PIRSF001549 1 373 5.7E-47 T 28-03-2018 IPR004516 Histidine-tRNA ligase/ATP phosphoribosyltransferase regulatory subunit GO:0005737 ALX04_RS07315 09a342ddfc76b0081f36e181eae564d1 383 Pfam PF13393 Histidyl-tRNA synthetase 9 313 3.5E-57 T 28-03-2018 ALX04_RS07315 09a342ddfc76b0081f36e181eae564d1 383 TIGRFAM TIGR00443 hisZ_biosyn_reg: ATP phosphoribosyltransferase, regulatory subunit 11 320 1.2E-83 T 28-03-2018 IPR004517 ATP phosphoribosyltransferase regulatory subunit GO:0000105|GO:0005737 ALX04_RS07315 09a342ddfc76b0081f36e181eae564d1 383 Gene3D G3DSA:3.30.930.10 65 327 2.2E-43 T 28-03-2018 ALX04_RS07315 09a342ddfc76b0081f36e181eae564d1 383 SUPERFAMILY SSF55681 4 323 8.87E-50 T 28-03-2018 ALX04_RS10720 15f9bdcf05ea9f33370b781b0f443110 344 Gene3D G3DSA:1.20.5.100 311 344 1.8E-5 T 28-03-2018 ALX04_RS10720 15f9bdcf05ea9f33370b781b0f443110 344 Gene3D G3DSA:2.60.40.1710 48 195 8.1E-4 T 28-03-2018 ALX04_RS10720 15f9bdcf05ea9f33370b781b0f443110 344 Pfam PF06030 Bacterial protein of unknown function (DUF916) 39 159 2.8E-31 T 28-03-2018 IPR010317 Protein of unknown function DUF916, cell surface putative ALX04_RS10720 15f9bdcf05ea9f33370b781b0f443110 344 Pfam PF11797 Protein of unknown function C-terminal (DUF3324) 168 308 1.9E-32 T 28-03-2018 IPR021759 Domain of unknown function DUF3324, C-terminal ALX04_RS04840 9ecbf6e8610da4b4d34b1d7815ea572a 380 Gene3D G3DSA:3.30.2400.10 142 235 1.3E-13 T 28-03-2018 ALX04_RS04840 9ecbf6e8610da4b4d34b1d7815ea572a 380 TIGRFAM TIGR01554 major_cap_HK97: phage major capsid protein, HK97 family 5 378 1.1E-59 T 28-03-2018 IPR024455 Phage capsid ALX04_RS04840 9ecbf6e8610da4b4d34b1d7815ea572a 380 SUPERFAMILY SSF56563 116 378 6.15E-36 T 28-03-2018 ALX04_RS04840 9ecbf6e8610da4b4d34b1d7815ea572a 380 Gene3D G3DSA:1.20.5.320 1 80 3.9E-4 T 28-03-2018 ALX04_RS04840 9ecbf6e8610da4b4d34b1d7815ea572a 380 Pfam PF05065 Phage capsid family 141 350 1.1E-23 T 28-03-2018 IPR024455 Phage capsid ALX04_RS04840 9ecbf6e8610da4b4d34b1d7815ea572a 380 Gene3D G3DSA:3.30.2320.10 240 348 1.4E-19 T 28-03-2018 ALX04_RS00275 451d8d88f0d83f6b5ea3b1ab8b51d3dc 483 ProSitePatterns PS00218 Amino acid permeases signature. 42 73 - T 28-03-2018 IPR004840 Amino acid permease, conserved site GO:0006865|GO:0016021|GO:0055085 ALX04_RS00275 451d8d88f0d83f6b5ea3b1ab8b51d3dc 483 Pfam PF00324 Amino acid permease 17 466 7.3E-132 T 28-03-2018 IPR004841 Amino acid permease/ SLC12A domain GO:0006810|GO:0016020|GO:0055085 ALX04_RS00275 451d8d88f0d83f6b5ea3b1ab8b51d3dc 483 PIRSF PIRSF006060 2 481 1.3E-80 T 28-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 ALX04_RS12975 e191ccc27bcfad0e5e127f9ff2844237 180 Gene3D G3DSA:1.10.260.40 1 70 4.6E-19 T 28-03-2018 ALX04_RS12975 e191ccc27bcfad0e5e127f9ff2844237 180 Pfam PF01381 Helix-turn-helix 7 61 2.1E-14 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 ALX04_RS12975 e191ccc27bcfad0e5e127f9ff2844237 180 SUPERFAMILY SSF47413 1 67 3.94E-18 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 ALX04_RS12975 e191ccc27bcfad0e5e127f9ff2844237 180 Gene3D G3DSA:2.60.120.10 71 179 3.8E-14 T 28-03-2018 IPR014710 RmlC-like jelly roll fold ALX04_RS12975 e191ccc27bcfad0e5e127f9ff2844237 180 Pfam PF07883 Cupin domain 107 174 2.7E-9 T 28-03-2018 IPR013096 Cupin 2, conserved barrel ALX04_RS12975 e191ccc27bcfad0e5e127f9ff2844237 180 SUPERFAMILY SSF51182 46 175 5.78E-24 T 28-03-2018 IPR011051 RmlC-like cupin domain ALX04_RS12975 e191ccc27bcfad0e5e127f9ff2844237 180 SMART SM00530 6 61 5.9E-15 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 ALX04_RS12030 5274cc720dddb9b286d181d34f980fa1 325 Pfam PF00107 Zinc-binding dehydrogenase 155 264 2.5E-14 T 28-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 ALX04_RS12030 5274cc720dddb9b286d181d34f980fa1 325 SUPERFAMILY SSF51735 116 291 1.42E-32 T 28-03-2018 IPR016040 NAD(P)-binding domain ALX04_RS12030 5274cc720dddb9b286d181d34f980fa1 325 SUPERFAMILY SSF50129 1 148 7.91E-39 T 28-03-2018 IPR011032 GroES-like ALX04_RS12030 5274cc720dddb9b286d181d34f980fa1 325 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 29 91 4.2E-10 T 28-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 ALX04_RS12030 5274cc720dddb9b286d181d34f980fa1 325 Gene3D G3DSA:3.40.50.720 140 304 3.9E-28 T 28-03-2018 ALX04_RS12030 5274cc720dddb9b286d181d34f980fa1 325 Gene3D G3DSA:3.90.180.10 1 139 6.4E-42 T 28-03-2018 ALX04_RS12030 5274cc720dddb9b286d181d34f980fa1 325 SMART SM00829 12 320 4.7E-40 T 28-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 ALX04_RS15255 6bbec46bb16bdd3ff1fa44ce6f72a8c7 618 Gene3D G3DSA:3.30.70.1450 536 618 1.2E-8 T 28-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 ALX04_RS15255 6bbec46bb16bdd3ff1fa44ce6f72a8c7 618 SUPERFAMILY SSF51735 407 524 1.57E-7 T 28-03-2018 IPR016040 NAD(P)-binding domain ALX04_RS15255 6bbec46bb16bdd3ff1fa44ce6f72a8c7 618 SUPERFAMILY SSF116726 541 613 4.45E-10 T 28-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 ALX04_RS15255 6bbec46bb16bdd3ff1fa44ce6f72a8c7 618 Pfam PF00999 Sodium/hydrogen exchanger family 7 388 4.1E-53 T 28-03-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 ALX04_RS15255 6bbec46bb16bdd3ff1fa44ce6f72a8c7 618 Pfam PF02080 TrkA-C domain 550 613 1.7E-8 T 28-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 ALX04_RS15255 6bbec46bb16bdd3ff1fa44ce6f72a8c7 618 Gene3D G3DSA:1.20.91.10 241 326 7.7E-16 T 28-03-2018 ALX04_RS15255 6bbec46bb16bdd3ff1fa44ce6f72a8c7 618 Gene3D G3DSA:3.40.50.720 404 532 3.4E-7 T 28-03-2018 ALX04_RS01240 d5209dab5a5d1e1a992bb895dc425517 75 Pfam PF11148 Protein of unknown function (DUF2922) 2 69 7.8E-17 T 28-03-2018 IPR021321 Protein of unknown function DUF2922 ALX04_RS09585 2f6878ba8ee3a705056e0cf03e9bb41a 121 Pfam PF01638 HxlR-like helix-turn-helix 22 111 8.7E-28 T 28-03-2018 IPR002577 Helix-turn-helix, HxlR type ALX04_RS09585 2f6878ba8ee3a705056e0cf03e9bb41a 121 SUPERFAMILY SSF46785 12 111 5.36E-28 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS09585 2f6878ba8ee3a705056e0cf03e9bb41a 121 Gene3D G3DSA:1.10.10.10 20 120 5.9E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS09650 b87200098cce4dba893ae431e96a4ba3 172 Gene3D G3DSA:1.25.40.10 38 145 8.6E-5 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 ALX04_RS04295 2b78811257f5d31105115ec77a7ea3c2 299 Gene3D G3DSA:3.40.50.300 2 248 3.3E-50 T 28-03-2018 ALX04_RS04295 2b78811257f5d31105115ec77a7ea3c2 299 SUPERFAMILY SSF52540 3 227 8.85E-50 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase ALX04_RS04295 2b78811257f5d31105115ec77a7ea3c2 299 SMART SM00382 30 207 6.3E-12 T 28-03-2018 IPR003593 AAA+ ATPase domain ALX04_RS04295 2b78811257f5d31105115ec77a7ea3c2 299 ProSitePatterns PS00211 ABC transporters family signature. 131 145 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 ALX04_RS04295 2b78811257f5d31105115ec77a7ea3c2 299 Pfam PF00005 ABC transporter 21 159 2.5E-25 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 ALX04_RS05260 b11a3526a4848555c4fc3bb0497e0b05 241 TIGRFAM TIGR00426 TIGR00426: competence protein ComEA helix-hairpin-helix repeat region 173 241 1.2E-22 T 28-03-2018 IPR004509 Competence protein ComEA, helix-hairpin-helix domain ALX04_RS05260 b11a3526a4848555c4fc3bb0497e0b05 241 Gene3D G3DSA:1.10.150.320 176 241 1.4E-24 T 28-03-2018 ALX04_RS05260 b11a3526a4848555c4fc3bb0497e0b05 241 SUPERFAMILY SSF47781 169 241 4.78E-30 T 28-03-2018 IPR010994 RuvA domain 2-like ALX04_RS05260 b11a3526a4848555c4fc3bb0497e0b05 241 Pfam PF12836 Helix-hairpin-helix motif 178 240 9.9E-24 T 28-03-2018 ALX04_RS05260 b11a3526a4848555c4fc3bb0497e0b05 241 SMART SM00278 189 208 0.17 T 28-03-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 ALX04_RS05260 b11a3526a4848555c4fc3bb0497e0b05 241 SMART SM00278 219 238 290.0 T 28-03-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 ALX04_RS05260 b11a3526a4848555c4fc3bb0497e0b05 241 Pfam PF10531 SLBB domain 92 147 1.5E-12 T 28-03-2018 IPR019554 Soluble ligand binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 ALX04_RS05260 b11a3526a4848555c4fc3bb0497e0b05 241 Gene3D G3DSA:3.10.560.10 84 175 3.0E-13 T 28-03-2018 ALX04_RS10985 ca6ca26d8ceecf2cce8e6b5df35afa8d 328 Pfam PF12833 Helix-turn-helix domain 243 320 2.9E-15 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 ALX04_RS10985 ca6ca26d8ceecf2cce8e6b5df35afa8d 328 SUPERFAMILY SSF46689 272 322 3.63E-10 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 ALX04_RS10985 ca6ca26d8ceecf2cce8e6b5df35afa8d 328 Gene3D G3DSA:2.60.120.280 40 228 1.1E-14 T 28-03-2018 ALX04_RS10985 ca6ca26d8ceecf2cce8e6b5df35afa8d 328 Pfam PF02311 AraC-like ligand binding domain 62 117 2.1E-6 T 28-03-2018 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 ALX04_RS10985 ca6ca26d8ceecf2cce8e6b5df35afa8d 328 SMART SM00342 236 319 3.6E-18 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 ALX04_RS10985 ca6ca26d8ceecf2cce8e6b5df35afa8d 328 SUPERFAMILY SSF51182 47 123 4.78E-8 T 28-03-2018 IPR011051 RmlC-like cupin domain ALX04_RS10985 ca6ca26d8ceecf2cce8e6b5df35afa8d 328 Gene3D G3DSA:1.10.10.60 269 324 8.2E-12 T 28-03-2018 ALX04_RS10985 ca6ca26d8ceecf2cce8e6b5df35afa8d 328 Gene3D G3DSA:1.10.10.60 229 268 6.4E-8 T 28-03-2018 ALX04_RS10985 ca6ca26d8ceecf2cce8e6b5df35afa8d 328 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 273 315 - T 28-03-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 ALX04_RS06010 3b5ba6f224278b25633a68599f643564 89 Hamap MF_01507 UPF0297 protein . 1 84 27.494 T 28-03-2018 IPR009309 Uncharacterised protein family UPF0297 ALX04_RS06010 3b5ba6f224278b25633a68599f643564 89 Pfam PF06135 Bacterial protein of unknown function (DUF965) 5 82 2.4E-37 T 28-03-2018 IPR009309 Uncharacterised protein family UPF0297 ALX04_RS06010 3b5ba6f224278b25633a68599f643564 89 PIRSF PIRSF037258 1 87 1.1E-45 T 28-03-2018 IPR009309 Uncharacterised protein family UPF0297 ALX04_RS02870 23b889fc2ff15b70508d7957af48d1fc 1185 Gene3D G3DSA:1.20.5.50 388 530 0.011 T 28-03-2018 ALX04_RS02870 23b889fc2ff15b70508d7957af48d1fc 1185 SUPERFAMILY SSF75553 488 681 3.14E-51 T 28-03-2018 IPR010935 SMCs flexible hinge GO:0005515|GO:0005524|GO:0005694|GO:0051276 ALX04_RS02870 23b889fc2ff15b70508d7957af48d1fc 1185 Pfam PF02463 RecF/RecN/SMC N terminal domain 3 1170 4.6E-65 T 28-03-2018 IPR003395 RecF/RecN/SMC, N-terminal ALX04_RS02870 23b889fc2ff15b70508d7957af48d1fc 1185 Gene3D G3DSA:1.20.1170.10 793 1037 9.6E-6 T 28-03-2018 ALX04_RS02870 23b889fc2ff15b70508d7957af48d1fc 1185 TIGRFAM TIGR02168 SMC_prok_B: chromosome segregation protein SMC 2 1177 0.0 T 28-03-2018 IPR011890 Structural maintenance of chromosomes protein, prokaryotic GO:0007062|GO:0030261 ALX04_RS02870 23b889fc2ff15b70508d7957af48d1fc 1185 Gene3D G3DSA:1.20.5.340 171 305 0.052 T 28-03-2018 ALX04_RS02870 23b889fc2ff15b70508d7957af48d1fc 1185 SUPERFAMILY SSF52540 975 1179 2.03E-60 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase ALX04_RS02870 23b889fc2ff15b70508d7957af48d1fc 1185 SUPERFAMILY SSF52540 1 207 2.03E-60 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase ALX04_RS02870 23b889fc2ff15b70508d7957af48d1fc 1185 SMART SM00968 519 638 1.3E-38 T 28-03-2018 IPR010935 SMCs flexible hinge GO:0005515|GO:0005524|GO:0005694|GO:0051276 ALX04_RS02870 23b889fc2ff15b70508d7957af48d1fc 1185 Gene3D G3DSA:3.40.50.300 1038 1181 1.1E-16 T 28-03-2018 ALX04_RS02870 23b889fc2ff15b70508d7957af48d1fc 1185 Hamap MF_01894 Chromosome partition protein Smc [smc]. 1 1179 23.491 T 28-03-2018 IPR011890 Structural maintenance of chromosomes protein, prokaryotic GO:0007062|GO:0030261 ALX04_RS02870 23b889fc2ff15b70508d7957af48d1fc 1185 Pfam PF06470 SMC proteins Flexible Hinge Domain 519 637 5.0E-30 T 28-03-2018 IPR010935 SMCs flexible hinge GO:0005515|GO:0005524|GO:0005694|GO:0051276 ALX04_RS02870 23b889fc2ff15b70508d7957af48d1fc 1185 PIRSF PIRSF005719 1 1185 2.4E-303 T 28-03-2018 IPR024704 Structural maintenance of chromosomes protein ALX04_RS02870 23b889fc2ff15b70508d7957af48d1fc 1185 Gene3D G3DSA:3.40.50.300 1 170 4.8E-40 T 28-03-2018 ALX04_RS02870 23b889fc2ff15b70508d7957af48d1fc 1185 Gene3D G3DSA:1.20.120.330 666 792 9.4E-5 T 28-03-2018 ALX04_RS05395 ea9a4a28b585fb7ec347f4f6e8794806 224 Gene3D G3DSA:1.25.40.10 137 200 3.7E-7 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 ALX04_RS05395 ea9a4a28b585fb7ec347f4f6e8794806 224 Gene3D G3DSA:1.25.40.10 9 82 5.9E-8 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 ALX04_RS05395 ea9a4a28b585fb7ec347f4f6e8794806 224 SUPERFAMILY SSF48452 65 204 3.11E-18 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 ALX04_RS05395 ea9a4a28b585fb7ec347f4f6e8794806 224 Pfam PF13432 Tetratricopeptide repeat 72 133 3.9E-4 T 28-03-2018 ALX04_RS05395 ea9a4a28b585fb7ec347f4f6e8794806 224 Pfam PF13432 Tetratricopeptide repeat 141 184 2.1E-4 T 28-03-2018 ALX04_RS05395 ea9a4a28b585fb7ec347f4f6e8794806 224 Gene3D G3DSA:1.25.40.10 83 136 8.1E-8 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 ALX04_RS07130 cc7a3a5888f8c30a386bcae6b892679f 395 Gene3D G3DSA:1.20.1250.20 4 191 2.1E-35 T 28-03-2018 ALX04_RS07130 cc7a3a5888f8c30a386bcae6b892679f 395 SUPERFAMILY SSF103473 5 389 2.75E-73 T 28-03-2018 IPR020846 Major facilitator superfamily domain ALX04_RS07130 cc7a3a5888f8c30a386bcae6b892679f 395 Pfam PF07690 Major Facilitator Superfamily 21 274 6.1E-39 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 ALX04_RS07130 cc7a3a5888f8c30a386bcae6b892679f 395 Gene3D G3DSA:1.20.1250.20 192 393 5.9E-21 T 28-03-2018 ALX04_RS06025 39569fddfda22ce06eef2988429e9182 318 Pfam PF01368 DHH family 17 154 3.0E-12 T 28-03-2018 IPR001667 DDH domain KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 ALX04_RS06025 39569fddfda22ce06eef2988429e9182 318 Gene3D G3DSA:3.90.1640.10 1 191 8.6E-40 T 28-03-2018 ALX04_RS06025 39569fddfda22ce06eef2988429e9182 318 SUPERFAMILY SSF64182 15 305 3.4E-65 T 28-03-2018 ALX04_RS06025 39569fddfda22ce06eef2988429e9182 318 Pfam PF02272 DHHA1 domain 252 310 1.0E-7 T 28-03-2018 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 ALX04_RS02280 d0f5778ddfa654624ad68ae1f991dc61 155 Gene3D G3DSA:3.90.1010.10 3 144 1.0E-46 T 28-03-2018 ALX04_RS02280 d0f5778ddfa654624ad68ae1f991dc61 155 SUPERFAMILY SSF82649 3 143 1.18E-45 T 28-03-2018 ALX04_RS02280 d0f5778ddfa654624ad68ae1f991dc61 155 Pfam PF01592 NifU-like N terminal domain 10 131 6.0E-24 T 28-03-2018 IPR002871 NIF system FeS cluster assembly, NifU, N-terminal GO:0005506|GO:0016226|GO:0051536 Reactome: R-HSA-1362409 ALX04_RS02280 d0f5778ddfa654624ad68ae1f991dc61 155 TIGRFAM TIGR01994 SUF_scaf_2: SUF system FeS assembly protein, NifU family 8 143 6.2E-52 T 28-03-2018 ALX04_RS12500 896c5cc3a5351d15363352a4656282fb 468 SMART SM00382 277 461 3.4E-11 T 28-03-2018 IPR003593 AAA+ ATPase domain ALX04_RS12500 896c5cc3a5351d15363352a4656282fb 468 SMART SM00382 30 218 9.0E-16 T 28-03-2018 IPR003593 AAA+ ATPase domain ALX04_RS12500 896c5cc3a5351d15363352a4656282fb 468 Gene3D G3DSA:3.40.50.300 245 464 2.4E-40 T 28-03-2018 ALX04_RS12500 896c5cc3a5351d15363352a4656282fb 468 SUPERFAMILY SSF52540 4 222 1.77E-54 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase ALX04_RS12500 896c5cc3a5351d15363352a4656282fb 468 Pfam PF00005 ABC transporter 277 411 3.9E-24 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 ALX04_RS12500 896c5cc3a5351d15363352a4656282fb 468 Pfam PF00005 ABC transporter 21 169 3.9E-27 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 ALX04_RS12500 896c5cc3a5351d15363352a4656282fb 468 ProSitePatterns PS00211 ABC transporters family signature. 141 155 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 ALX04_RS12500 896c5cc3a5351d15363352a4656282fb 468 SUPERFAMILY SSF52540 255 460 9.69E-39 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase ALX04_RS12500 896c5cc3a5351d15363352a4656282fb 468 Gene3D G3DSA:3.40.50.300 1 244 2.1E-58 T 28-03-2018 ALX04_RS11130 3e6b92d20c4aea5deac12e1b40391639 243 SMART SM00345 11 70 1.1E-5 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 ALX04_RS11130 3e6b92d20c4aea5deac12e1b40391639 243 Gene3D G3DSA:3.40.1410.10 77 236 2.3E-18 T 28-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain ALX04_RS11130 3e6b92d20c4aea5deac12e1b40391639 243 SUPERFAMILY SSF46785 3 74 4.49E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS11130 3e6b92d20c4aea5deac12e1b40391639 243 Pfam PF07702 UTRA domain 98 226 2.3E-13 T 28-03-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 ALX04_RS11130 3e6b92d20c4aea5deac12e1b40391639 243 Gene3D G3DSA:1.10.10.10 1 76 7.5E-14 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS11130 3e6b92d20c4aea5deac12e1b40391639 243 SMART SM00866 84 227 1.4E-9 T 28-03-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 ALX04_RS11130 3e6b92d20c4aea5deac12e1b40391639 243 Pfam PF00392 Bacterial regulatory proteins, gntR family 8 70 7.6E-10 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 ALX04_RS11130 3e6b92d20c4aea5deac12e1b40391639 243 SUPERFAMILY SSF64288 58 229 2.98E-20 T 28-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain ALX04_RS14145 0cf8e0cf65617066c48b8b3836f52d7d 139 Pfam PF03610 PTS system fructose IIA component 4 108 9.5E-32 T 28-03-2018 IPR004701 Phosphotransferase system, mannose-type IIA component GO:0009401|GO:0016021 ALX04_RS14145 0cf8e0cf65617066c48b8b3836f52d7d 139 Gene3D G3DSA:3.40.50.510 1 138 4.3E-40 T 28-03-2018 IPR004701 Phosphotransferase system, mannose-type IIA component GO:0009401|GO:0016021 ALX04_RS14145 0cf8e0cf65617066c48b8b3836f52d7d 139 TIGRFAM TIGR00824 EIIA-man: PTS system, mannose/fructose/sorbose family, IIA component 1 115 4.0E-32 T 28-03-2018 IPR013789 Phosphotransferase system, mannose family IIA component GO:0005737|GO:0008643|GO:0016773 ALX04_RS14145 0cf8e0cf65617066c48b8b3836f52d7d 139 SUPERFAMILY SSF53062 1 131 2.62E-37 T 28-03-2018 IPR004701 Phosphotransferase system, mannose-type IIA component GO:0009401|GO:0016021 ALX04_RS04220 c45e4e7d24985de6a4abf7b263013e80 296 Pfam PF03466 LysR substrate binding domain 86 287 1.4E-29 T 28-03-2018 IPR005119 LysR, substrate-binding ALX04_RS04220 c45e4e7d24985de6a4abf7b263013e80 296 Gene3D G3DSA:1.10.10.10 1 83 1.8E-23 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS04220 c45e4e7d24985de6a4abf7b263013e80 296 Gene3D G3DSA:3.40.190.10 87 176 6.9E-16 T 28-03-2018 ALX04_RS04220 c45e4e7d24985de6a4abf7b263013e80 296 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 62 3.5E-23 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 ALX04_RS04220 c45e4e7d24985de6a4abf7b263013e80 296 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 2.0E-11 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 ALX04_RS04220 c45e4e7d24985de6a4abf7b263013e80 296 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 2.0E-11 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 ALX04_RS04220 c45e4e7d24985de6a4abf7b263013e80 296 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 2.0E-11 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 ALX04_RS04220 c45e4e7d24985de6a4abf7b263013e80 296 Gene3D G3DSA:3.40.190.10 177 264 6.0E-10 T 28-03-2018 ALX04_RS04220 c45e4e7d24985de6a4abf7b263013e80 296 SUPERFAMILY SSF53850 87 292 2.3E-28 T 28-03-2018 ALX04_RS04220 c45e4e7d24985de6a4abf7b263013e80 296 SUPERFAMILY SSF46785 1 83 2.57E-24 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS05340 4d7094595d6653a0b8332e02c040e1e5 325 SUPERFAMILY SSF52518 1 204 1.0E-61 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold ALX04_RS05340 4d7094595d6653a0b8332e02c040e1e5 325 Gene3D G3DSA:3.40.50.920 195 324 3.8E-31 T 28-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 ALX04_RS05340 4d7094595d6653a0b8332e02c040e1e5 325 Pfam PF02780 Transketolase, C-terminal domain 195 313 2.3E-36 T 28-03-2018 IPR033248 Transketolase, C-terminal domain ALX04_RS05340 4d7094595d6653a0b8332e02c040e1e5 325 SMART SM00861 4 179 2.7E-59 T 28-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain ALX04_RS05340 4d7094595d6653a0b8332e02c040e1e5 325 Pfam PF02779 Transketolase, pyrimidine binding domain 4 178 8.8E-36 T 28-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain ALX04_RS05340 4d7094595d6653a0b8332e02c040e1e5 325 Gene3D G3DSA:3.40.50.970 1 194 4.9E-56 T 28-03-2018 ALX04_RS05340 4d7094595d6653a0b8332e02c040e1e5 325 SUPERFAMILY SSF52922 189 325 7.33E-38 T 28-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 ALX04_RS04255 5153482e53b8281ad127833f0ef77a86 295 SMART SM00382 29 205 3.0E-14 T 28-03-2018 IPR003593 AAA+ ATPase domain ALX04_RS04255 5153482e53b8281ad127833f0ef77a86 295 Pfam PF00005 ABC transporter 20 156 1.3E-25 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 ALX04_RS04255 5153482e53b8281ad127833f0ef77a86 295 Gene3D G3DSA:3.40.50.300 1 270 1.6E-60 T 28-03-2018 ALX04_RS04255 5153482e53b8281ad127833f0ef77a86 295 SUPERFAMILY SSF52540 3 226 2.44E-57 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase ALX04_RS04255 5153482e53b8281ad127833f0ef77a86 295 ProSitePatterns PS00211 ABC transporters family signature. 129 143 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 ALX04_RS04435 64b541a6bd47fabc8c3670c8d5be95ec 207 SUPERFAMILY SSF56784 2 206 2.85E-37 T 28-03-2018 IPR023214 HAD-like domain ALX04_RS04435 64b541a6bd47fabc8c3670c8d5be95ec 207 Pfam PF13419 Haloacid dehalogenase-like hydrolase 5 176 6.5E-25 T 28-03-2018 IPR023214 HAD-like domain ALX04_RS04435 64b541a6bd47fabc8c3670c8d5be95ec 207 Gene3D G3DSA:3.40.50.1000 63 181 5.9E-20 T 28-03-2018 IPR023214 HAD-like domain ALX04_RS04435 64b541a6bd47fabc8c3670c8d5be95ec 207 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 101 174 7.7E-8 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 ALX04_RS04435 64b541a6bd47fabc8c3670c8d5be95ec 207 Gene3D G3DSA:1.10.150.240 14 62 2.1E-19 T 28-03-2018 IPR023198 Phosphoglycolate phosphatase, domain 2 ALX04_RS10665 578bca602fb4587816eec2234cbcff60 310 Pfam PF03547 Membrane transport protein 165 301 7.0E-12 T 28-03-2018 IPR004776 Membrane transport protein GO:0016021|GO:0055085 ALX04_RS10665 578bca602fb4587816eec2234cbcff60 310 Pfam PF03547 Membrane transport protein 4 147 2.3E-6 T 28-03-2018 IPR004776 Membrane transport protein GO:0016021|GO:0055085 ALX04_RS11380 344f83d312c75eabac2c6fe5d3f1ebaf 42 TIGRFAM TIGR04223 quorum_AgrD: cyclic lactone autoinducer peptide 4 39 3.0E-6 T 28-03-2018 IPR009229 Staphylococcal AgrD ALX04_RS08515 1eb3a3567240fde0cb5eae666a531643 233 ProSitePatterns PS00211 ABC transporters family signature. 139 153 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 ALX04_RS08515 1eb3a3567240fde0cb5eae666a531643 233 Pfam PF00005 ABC transporter 25 166 5.8E-37 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 ALX04_RS08515 1eb3a3567240fde0cb5eae666a531643 233 Gene3D G3DSA:3.40.50.300 1 225 4.8E-62 T 28-03-2018 ALX04_RS08515 1eb3a3567240fde0cb5eae666a531643 233 SUPERFAMILY SSF52540 4 221 1.27E-66 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase ALX04_RS08515 1eb3a3567240fde0cb5eae666a531643 233 SMART SM00382 32 215 7.8E-15 T 28-03-2018 IPR003593 AAA+ ATPase domain ALX04_RS11045 55daac98ceb5dfac0d0294373bab9582 331 Gene3D G3DSA:3.40.50.2300 163 331 4.7E-38 T 28-03-2018 ALX04_RS11045 55daac98ceb5dfac0d0294373bab9582 331 Pfam PF13377 Periplasmic binding protein-like domain 164 330 5.0E-34 T 28-03-2018 ALX04_RS11045 55daac98ceb5dfac0d0294373bab9582 331 ProSitePatterns PS00356 LacI-type HTH domain signature. 5 23 - T 28-03-2018 ALX04_RS11045 55daac98ceb5dfac0d0294373bab9582 331 Gene3D G3DSA:1.10.260.40 2 38 3.7E-13 T 28-03-2018 ALX04_RS11045 55daac98ceb5dfac0d0294373bab9582 331 Pfam PF00356 Bacterial regulatory proteins, lacI family 4 51 8.2E-16 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 ALX04_RS11045 55daac98ceb5dfac0d0294373bab9582 331 Gene3D G3DSA:3.40.50.2300 58 162 0.048 T 28-03-2018 ALX04_RS11045 55daac98ceb5dfac0d0294373bab9582 331 SUPERFAMILY SSF47413 4 52 8.81E-12 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 ALX04_RS11045 55daac98ceb5dfac0d0294373bab9582 331 Gene3D G3DSA:1.10.10.60 39 57 0.31 T 28-03-2018 ALX04_RS11045 55daac98ceb5dfac0d0294373bab9582 331 SMART SM00354 2 72 2.0E-11 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 ALX04_RS11045 55daac98ceb5dfac0d0294373bab9582 331 SUPERFAMILY SSF53822 75 324 3.08E-46 T 28-03-2018 IPR028082 Periplasmic binding protein-like I ALX04_RS11045 55daac98ceb5dfac0d0294373bab9582 331 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 14 24 1.7E-5 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 ALX04_RS11045 55daac98ceb5dfac0d0294373bab9582 331 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 4 14 1.7E-5 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 ALX04_RS10485 b5e44251ab1696989ef312c747c59143 298 Pfam PF06028 Alpha/beta hydrolase of unknown function (DUF915) 51 298 1.0E-64 T 28-03-2018 IPR010315 Protein of unknown function DUF915, hydrolase-like ALX04_RS10485 b5e44251ab1696989ef312c747c59143 298 Gene3D G3DSA:3.40.50.1820 54 298 4.3E-25 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold ALX04_RS10485 b5e44251ab1696989ef312c747c59143 298 SUPERFAMILY SSF53474 54 287 5.41E-14 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold ALX04_RS06370 909eed9317fabc370df7c2f6200ad28c 98 Pfam PF01597 Glycine cleavage H-protein 9 97 1.2E-19 T 28-03-2018 IPR033753 Glycine cleavage system H-protein/Simiate ALX04_RS06370 909eed9317fabc370df7c2f6200ad28c 98 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 41 70 - T 28-03-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 ALX04_RS06370 909eed9317fabc370df7c2f6200ad28c 98 Gene3D G3DSA:2.40.50.100 4 98 2.1E-21 T 28-03-2018 ALX04_RS06370 909eed9317fabc370df7c2f6200ad28c 98 SUPERFAMILY SSF51230 7 97 2.62E-20 T 28-03-2018 IPR011053 Single hybrid motif ALX04_RS02630 a5a145c2b69b59bf68dc105138810e26 126 SUPERFAMILY SSF46955 14 88 1.36E-19 T 28-03-2018 IPR009061 Putative DNA-binding domain ALX04_RS02630 a5a145c2b69b59bf68dc105138810e26 126 Gene3D G3DSA:1.10.1660.10 2 111 3.5E-23 T 28-03-2018 ALX04_RS02630 a5a145c2b69b59bf68dc105138810e26 126 Pfam PF13411 MerR HTH family regulatory protein 14 77 2.6E-17 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 ALX04_RS02630 a5a145c2b69b59bf68dc105138810e26 126 SMART SM00422 13 81 1.2E-23 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 ALX04_RS10825 f9b4fd34d3fc97e8be9ba8660b9f5f56 634 Gene3D G3DSA:3.40.1110.10 321 434 4.9E-24 T 28-03-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 ALX04_RS10825 f9b4fd34d3fc97e8be9ba8660b9f5f56 634 TIGRFAM TIGR01511 ATPase-IB1_Cu: copper-translocating P-type ATPase 55 613 3.5E-125 T 28-03-2018 ALX04_RS10825 f9b4fd34d3fc97e8be9ba8660b9f5f56 634 Pfam PF00122 E1-E2 ATPase 119 290 8.0E-49 T 28-03-2018 ALX04_RS10825 f9b4fd34d3fc97e8be9ba8660b9f5f56 634 Gene3D G3DSA:3.40.50.1000 435 577 7.6E-41 T 28-03-2018 IPR023214 HAD-like domain ALX04_RS10825 f9b4fd34d3fc97e8be9ba8660b9f5f56 634 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 91 593 6.3E-78 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 ALX04_RS10825 f9b4fd34d3fc97e8be9ba8660b9f5f56 634 SUPERFAMILY SSF81665 219 304 4.18E-11 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 ALX04_RS10825 f9b4fd34d3fc97e8be9ba8660b9f5f56 634 SUPERFAMILY SSF81665 560 590 4.18E-11 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 ALX04_RS10825 f9b4fd34d3fc97e8be9ba8660b9f5f56 634 SUPERFAMILY SSF81665 70 122 4.18E-11 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 ALX04_RS10825 f9b4fd34d3fc97e8be9ba8660b9f5f56 634 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 68 613 5.7E-168 T 28-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 ALX04_RS10825 f9b4fd34d3fc97e8be9ba8660b9f5f56 634 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 168 182 3.0E-21 T 28-03-2018 ALX04_RS10825 f9b4fd34d3fc97e8be9ba8660b9f5f56 634 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 511 530 3.0E-21 T 28-03-2018 ALX04_RS10825 f9b4fd34d3fc97e8be9ba8660b9f5f56 634 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 310 324 3.0E-21 T 28-03-2018 ALX04_RS10825 f9b4fd34d3fc97e8be9ba8660b9f5f56 634 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 458 468 3.0E-21 T 28-03-2018 ALX04_RS10825 f9b4fd34d3fc97e8be9ba8660b9f5f56 634 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 534 546 3.0E-21 T 28-03-2018 ALX04_RS10825 f9b4fd34d3fc97e8be9ba8660b9f5f56 634 Gene3D G3DSA:2.70.150.10 9 219 3.9E-30 T 28-03-2018 ALX04_RS10825 f9b4fd34d3fc97e8be9ba8660b9f5f56 634 SUPERFAMILY SSF81653 121 218 9.68E-25 T 28-03-2018 IPR008250 P-type ATPase, A domain Reactome: R-HSA-936837 ALX04_RS10825 f9b4fd34d3fc97e8be9ba8660b9f5f56 634 SUPERFAMILY SSF56784 367 611 1.15E-48 T 28-03-2018 IPR023214 HAD-like domain ALX04_RS10825 f9b4fd34d3fc97e8be9ba8660b9f5f56 634 SUPERFAMILY SSF56784 308 328 1.15E-48 T 28-03-2018 IPR023214 HAD-like domain ALX04_RS10825 f9b4fd34d3fc97e8be9ba8660b9f5f56 634 Pfam PF00702 haloacid dehalogenase-like hydrolase 306 525 2.1E-43 T 28-03-2018 ALX04_RS10825 f9b4fd34d3fc97e8be9ba8660b9f5f56 634 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 312 318 - T 28-03-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 ALX04_RS15845 da06d6473d976639940459af6fccc3ed 408 Gene3D G3DSA:1.10.340.30 61 286 0.0013 T 28-03-2018 ALX04_RS15845 da06d6473d976639940459af6fccc3ed 408 Pfam PF01548 Transposase 6 156 2.2E-29 T 28-03-2018 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 ALX04_RS15845 da06d6473d976639940459af6fccc3ed 408 Pfam PF02371 Transposase IS116/IS110/IS902 family 268 340 3.2E-24 T 28-03-2018 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 ALX04_RS00780 6d2d6d6f293d1c62fed1dc75f1e7669c 193 Pfam PF12822 ECF transporter, substrate-specific component 12 185 1.4E-26 T 28-03-2018 IPR024529 ECF transporter, substrate-specific component GO:0005215 ALX04_RS02275 81a341f158bb9036679b36dd86958467 412 Gene3D G3DSA:3.90.1150.10 283 403 6.3E-44 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 ALX04_RS02275 81a341f158bb9036679b36dd86958467 412 PIRSF PIRSF005572 22 408 2.0E-51 T 28-03-2018 IPR016454 Cysteine desulfurase KEGG: 00730+2.8.1.7|MetaCyc: PWY-6823|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7250 ALX04_RS02275 81a341f158bb9036679b36dd86958467 412 TIGRFAM TIGR01979 sufS: cysteine desulfurase, SufS family 7 407 5.1E-186 T 28-03-2018 IPR010970 Cysteine desulfurase, SufS GO:0006534|GO:0030170|GO:0031071 KEGG: 00730+2.8.1.7|MetaCyc: PWY-6823|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7250 ALX04_RS02275 81a341f158bb9036679b36dd86958467 412 Gene3D G3DSA:3.40.640.10 34 282 2.2E-61 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 ALX04_RS02275 81a341f158bb9036679b36dd86958467 412 SUPERFAMILY SSF53383 4 402 6.78E-127 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase ALX04_RS02275 81a341f158bb9036679b36dd86958467 412 Pfam PF00266 Aminotransferase class-V 25 396 5.3E-152 T 28-03-2018 IPR000192 Aminotransferase class V domain ALX04_RS02275 81a341f158bb9036679b36dd86958467 412 ProSitePatterns PS00595 Aminotransferases class-V pyridoxal-phosphate attachment site. 217 236 - T 28-03-2018 IPR020578 Aminotransferase class-V, pyridoxal-phosphate binding site ALX04_RS13620 1fd3468210a081dc5edae30805d5274c 202 Hamap MF_00357 Probable DNA-directed RNA polymerase subunit delta [rpoE]. 9 199 14.985 T 28-03-2018 IPR029757 DNA-directed RNA polymerase subunit delta GO:0006351|GO:0006355 ALX04_RS13620 1fd3468210a081dc5edae30805d5274c 202 Pfam PF05066 HB1, ASXL, restriction endonuclease HTH domain 15 81 2.2E-12 T 28-03-2018 IPR007759 HB1/Asxl, restriction endonuclease HTH domain GO:0006351|GO:0006355 ALX04_RS13620 1fd3468210a081dc5edae30805d5274c 202 TIGRFAM TIGR04567 RNAP_delt_lowGC: DNA-directed RNA polymerase delta subunit 13 92 3.6E-34 T 28-03-2018 IPR029757 DNA-directed RNA polymerase subunit delta GO:0006351|GO:0006355 ALX04_RS11480 3b09cfccf7db22267db1b8e4dc970697 181 Pfam PF03551 Transcriptional regulator PadR-like family 11 85 1.2E-21 T 28-03-2018 IPR005149 Transcription regulator PadR, N-terminal ALX04_RS11480 3b09cfccf7db22267db1b8e4dc970697 181 SUPERFAMILY SSF46785 7 179 2.38E-42 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS11480 3b09cfccf7db22267db1b8e4dc970697 181 Pfam PF10400 Virulence activator alpha C-term 97 179 1.1E-17 T 28-03-2018 IPR018309 Transcription regulator PadR, C-terminal ALX04_RS11480 3b09cfccf7db22267db1b8e4dc970697 181 Gene3D G3DSA:1.10.10.10 1 93 6.2E-27 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS11105 99e8b5b8256ccfa031fab925f1b0aeca 283 Gene3D G3DSA:3.20.20.150 1 279 3.9E-37 T 28-03-2018 ALX04_RS11105 99e8b5b8256ccfa031fab925f1b0aeca 283 Pfam PF01261 Xylose isomerase-like TIM barrel 25 220 1.6E-15 T 28-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain ALX04_RS11105 99e8b5b8256ccfa031fab925f1b0aeca 283 SUPERFAMILY SSF51658 5 275 1.66E-66 T 28-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain ALX04_RS04465 8e7385e399ff1ca3860570ca94c9bddb 209 SUPERFAMILY SSF50486 3 199 1.1E-57 T 28-03-2018 IPR011034 Formyl transferase, C-terminal-like GO:0003824 ALX04_RS04465 8e7385e399ff1ca3860570ca94c9bddb 209 Pfam PF02245 Methylpurine-DNA glycosylase (MPG) 10 189 3.8E-52 T 28-03-2018 IPR003180 Methylpurine-DNA glycosylase (MPG) GO:0003677|GO:0003905|GO:0006284 Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 ALX04_RS04465 8e7385e399ff1ca3860570ca94c9bddb 209 Hamap MF_00527 Putative 3-methyladenine DNA glycosylase. 5 192 27.7 T 28-03-2018 IPR003180 Methylpurine-DNA glycosylase (MPG) GO:0003677|GO:0003905|GO:0006284 Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 ALX04_RS04465 8e7385e399ff1ca3860570ca94c9bddb 209 TIGRFAM TIGR00567 3mg: DNA-3-methyladenine glycosylase 12 192 3.0E-47 T 28-03-2018 IPR003180 Methylpurine-DNA glycosylase (MPG) GO:0003677|GO:0003905|GO:0006284 Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 ALX04_RS04465 8e7385e399ff1ca3860570ca94c9bddb 209 Gene3D G3DSA:3.10.300.10 1 200 5.7E-57 T 28-03-2018 IPR003180 Methylpurine-DNA glycosylase (MPG) GO:0003677|GO:0003905|GO:0006284 Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 ALX04_RS05525 f917554560498392119933f0588ac593 363 Pfam PF04101 Glycosyltransferase family 28 C-terminal domain 189 354 8.8E-38 T 28-03-2018 IPR007235 Glycosyl transferase, family 28, C-terminal GO:0016758 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193 ALX04_RS05525 f917554560498392119933f0588ac593 363 Gene3D G3DSA:3.40.50.2000 1 177 3.1E-40 T 28-03-2018 ALX04_RS05525 f917554560498392119933f0588ac593 363 Gene3D G3DSA:3.40.50.2000 178 346 1.8E-29 T 28-03-2018 ALX04_RS05525 f917554560498392119933f0588ac593 363 Pfam PF03033 Glycosyltransferase family 28 N-terminal domain 4 142 1.0E-46 T 28-03-2018 IPR004276 Glycosyltransferase family 28, N-terminal domain GO:0005975|GO:0016758|GO:0030259 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 ALX04_RS05525 f917554560498392119933f0588ac593 363 TIGRFAM TIGR01133 murG: undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase 1 357 8.9E-99 T 28-03-2018 IPR006009 N-acetylglucosaminyltransferase, MurG GO:0009252|GO:0050511 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 ALX04_RS05525 f917554560498392119933f0588ac593 363 Hamap MF_00033 UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [murG]. 3 362 33.524 T 28-03-2018 IPR006009 N-acetylglucosaminyltransferase, MurG GO:0009252|GO:0050511 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 ALX04_RS05525 f917554560498392119933f0588ac593 363 SUPERFAMILY SSF53756 1 362 5.18E-107 T 28-03-2018 ALX04_RS06195 406319c865321fec1bdb995b368dcef5 444 TIGRFAM TIGR01499 folC: bifunctional protein FolC 24 434 9.8E-125 T 28-03-2018 IPR001645 Folylpolyglutamate synthetase GO:0004326|GO:0005524|GO:0009396 KEGG: 00790+6.3.2.17|MetaCyc: PWY-2161|Reactome: R-HSA-196757 ALX04_RS06195 406319c865321fec1bdb995b368dcef5 444 Gene3D G3DSA:3.90.190.20 301 440 1.4E-21 T 28-03-2018 ALX04_RS06195 406319c865321fec1bdb995b368dcef5 444 SUPERFAMILY SSF53623 4 299 3.89E-89 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 ALX04_RS06195 406319c865321fec1bdb995b368dcef5 444 Pfam PF02875 Mur ligase family, glutamate ligase domain 299 356 2.1E-5 T 28-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 ALX04_RS06195 406319c865321fec1bdb995b368dcef5 444 Gene3D G3DSA:3.40.1190.10 3 300 1.4E-78 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 ALX04_RS06195 406319c865321fec1bdb995b368dcef5 444 SUPERFAMILY SSF53244 299 436 1.48E-22 T 28-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 ALX04_RS06195 406319c865321fec1bdb995b368dcef5 444 Pfam PF08245 Mur ligase middle domain 46 273 7.7E-14 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 ALX04_RS06195 406319c865321fec1bdb995b368dcef5 444 PIRSF PIRSF001563 1 441 6.8E-145 T 28-03-2018 IPR001645 Folylpolyglutamate synthetase GO:0004326|GO:0005524|GO:0009396 KEGG: 00790+6.3.2.17|MetaCyc: PWY-2161|Reactome: R-HSA-196757 ALX04_RS00350 08378c0b37e637ca695b95df82e41a82 1213 Pfam PF04997 RNA polymerase Rpb1, domain 1 5 331 5.1E-88 T 28-03-2018 IPR007080 RNA polymerase Rpb1, domain 1 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 ALX04_RS00350 08378c0b37e637ca695b95df82e41a82 1213 Pfam PF04998 RNA polymerase Rpb1, domain 5 770 1130 1.0E-62 T 28-03-2018 IPR007081 RNA polymerase Rpb1, domain 5 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 ALX04_RS00350 08378c0b37e637ca695b95df82e41a82 1213 Gene3D G3DSA:2.40.50.100 911 1028 1.2E-36 T 28-03-2018 ALX04_RS00350 08378c0b37e637ca695b95df82e41a82 1213 Hamap MF_01322 DNA-directed RNA polymerase subunit beta' [rpoC]. 4 1192 18.374 T 28-03-2018 IPR012754 DNA-directed RNA polymerase, subunit beta-prime GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 ALX04_RS00350 08378c0b37e637ca695b95df82e41a82 1213 SUPERFAMILY SSF64484 5 1182 0.0 T 28-03-2018 ALX04_RS00350 08378c0b37e637ca695b95df82e41a82 1213 Gene3D G3DSA:2.40.40.20 335 477 5.3E-37 T 28-03-2018 ALX04_RS00350 08378c0b37e637ca695b95df82e41a82 1213 SMART SM00663 224 503 1.5E-174 T 28-03-2018 IPR006592 RNA polymerase, N-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 ALX04_RS00350 08378c0b37e637ca695b95df82e41a82 1213 TIGRFAM TIGR02386 rpoC_TIGR: DNA-directed RNA polymerase, beta' subunit 10 1182 0.0 T 28-03-2018 IPR012754 DNA-directed RNA polymerase, subunit beta-prime GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 ALX04_RS00350 08378c0b37e637ca695b95df82e41a82 1213 Pfam PF04983 RNA polymerase Rpb1, domain 3 478 663 4.5E-32 T 28-03-2018 IPR007066 RNA polymerase Rpb1, domain 3 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 ALX04_RS00350 08378c0b37e637ca695b95df82e41a82 1213 Pfam PF00623 RNA polymerase Rpb1, domain 2 333 474 7.0E-38 T 28-03-2018 IPR000722 RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 ALX04_RS00350 08378c0b37e637ca695b95df82e41a82 1213 Pfam PF05000 RNA polymerase Rpb1, domain 4 692 756 7.4E-14 T 28-03-2018 IPR007083 RNA polymerase Rpb1, domain 4 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 ALX04_RS02735 6bed45d0a0a1ad66cf7254e263a137fc 296 Gene3D G3DSA:1.10.600.10 2 284 1.0E-71 T 28-03-2018 IPR008949 Isoprenoid synthase domain ALX04_RS02735 6bed45d0a0a1ad66cf7254e263a137fc 296 ProSitePatterns PS00723 Polyprenyl synthases signature 1. 84 100 - T 28-03-2018 IPR033749 Polyprenyl synthetase, conserved site ALX04_RS02735 6bed45d0a0a1ad66cf7254e263a137fc 296 ProSitePatterns PS00444 Polyprenyl synthases signature 2. 214 226 - T 28-03-2018 IPR033749 Polyprenyl synthetase, conserved site ALX04_RS02735 6bed45d0a0a1ad66cf7254e263a137fc 296 SUPERFAMILY SSF48576 8 272 8.43E-76 T 28-03-2018 IPR008949 Isoprenoid synthase domain ALX04_RS02735 6bed45d0a0a1ad66cf7254e263a137fc 296 Pfam PF00348 Polyprenyl synthetase 33 265 1.3E-49 T 28-03-2018 IPR000092 Polyprenyl synthetase GO:0008299 ALX04_RS10535 e816982394810f00831c752e42aae0a7 147 Pfam PF00011 Hsp20/alpha crystallin family 46 147 3.5E-22 T 28-03-2018 IPR002068 Alpha crystallin/Hsp20 domain ALX04_RS10535 e816982394810f00831c752e42aae0a7 147 SUPERFAMILY SSF49764 6 146 2.44E-32 T 28-03-2018 IPR008978 HSP20-like chaperone ALX04_RS10535 e816982394810f00831c752e42aae0a7 147 Gene3D G3DSA:2.60.40.790 1 147 1.1E-30 T 28-03-2018 IPR008978 HSP20-like chaperone ALX04_RS11315 f969d1564c40e85bb245e23bf2d7aca4 466 SUPERFAMILY SSF103473 9 449 1.03E-79 T 28-03-2018 IPR020846 Major facilitator superfamily domain ALX04_RS11315 f969d1564c40e85bb245e23bf2d7aca4 466 ProSitePatterns PS00216 Sugar transport proteins signature 1. 67 84 - T 28-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 ALX04_RS11315 f969d1564c40e85bb245e23bf2d7aca4 466 ProSitePatterns PS00217 Sugar transport proteins signature 2. 111 136 - T 28-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 ALX04_RS11315 f969d1564c40e85bb245e23bf2d7aca4 466 Gene3D G3DSA:1.20.1250.20 2 223 1.1E-39 T 28-03-2018 ALX04_RS11315 f969d1564c40e85bb245e23bf2d7aca4 466 Gene3D G3DSA:1.20.1250.20 227 464 3.6E-37 T 28-03-2018 ALX04_RS11315 f969d1564c40e85bb245e23bf2d7aca4 466 Pfam PF00083 Sugar (and other) transporter 15 450 7.1E-116 T 28-03-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 ALX04_RS11315 f969d1564c40e85bb245e23bf2d7aca4 466 TIGRFAM TIGR00879 SP: MFS transporter, sugar porter (SP) family 11 448 4.8E-108 T 28-03-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 ALX04_RS11315 f969d1564c40e85bb245e23bf2d7aca4 466 PRINTS PR00171 Sugar transporter signature 265 275 2.6E-25 T 28-03-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 ALX04_RS11315 f969d1564c40e85bb245e23bf2d7aca4 466 PRINTS PR00171 Sugar transporter signature 20 30 2.6E-25 T 28-03-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 ALX04_RS11315 f969d1564c40e85bb245e23bf2d7aca4 466 PRINTS PR00171 Sugar transporter signature 376 388 2.6E-25 T 28-03-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 ALX04_RS11315 f969d1564c40e85bb245e23bf2d7aca4 466 PRINTS PR00171 Sugar transporter signature 106 125 2.6E-25 T 28-03-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 ALX04_RS11315 f969d1564c40e85bb245e23bf2d7aca4 466 PRINTS PR00171 Sugar transporter signature 353 374 2.6E-25 T 28-03-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 ALX04_RS08155 2a38ff9b942879b165e2cd59d8633f9f 479 PRINTS PR00131 Glycosyl hydrolase family 1 signature 373 381 1.2E-15 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 ALX04_RS08155 2a38ff9b942879b165e2cd59d8633f9f 479 PRINTS PR00131 Glycosyl hydrolase family 1 signature 307 321 1.2E-15 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 ALX04_RS08155 2a38ff9b942879b165e2cd59d8633f9f 479 PRINTS PR00131 Glycosyl hydrolase family 1 signature 416 433 1.2E-15 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 ALX04_RS08155 2a38ff9b942879b165e2cd59d8633f9f 479 PRINTS PR00131 Glycosyl hydrolase family 1 signature 441 453 1.2E-15 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 ALX04_RS08155 2a38ff9b942879b165e2cd59d8633f9f 479 PRINTS PR00131 Glycosyl hydrolase family 1 signature 394 405 1.2E-15 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 ALX04_RS08155 2a38ff9b942879b165e2cd59d8633f9f 479 ProSitePatterns PS00653 Glycosyl hydrolases family 1 N-terminal signature. 11 25 - T 28-03-2018 IPR033132 Glycosyl hydrolases family 1, N-terminal conserved site ALX04_RS08155 2a38ff9b942879b165e2cd59d8633f9f 479 Pfam PF00232 Glycosyl hydrolase family 1 6 476 4.8E-128 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 ALX04_RS08155 2a38ff9b942879b165e2cd59d8633f9f 479 SUPERFAMILY SSF51445 4 472 4.29E-161 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily ALX04_RS08155 2a38ff9b942879b165e2cd59d8633f9f 479 Gene3D G3DSA:3.20.20.80 4 479 4.2E-147 T 28-03-2018 ALX04_RS05270 1e7e0be2f298de004efe870be2f13dc9 163 Hamap MF_00151 Phosphopantetheine adenylyltransferase [coaD]. 2 158 31.676 T 28-03-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 ALX04_RS05270 1e7e0be2f298de004efe870be2f13dc9 163 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 2 20 1.6E-39 T 28-03-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 ALX04_RS05270 1e7e0be2f298de004efe870be2f13dc9 163 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 49 73 1.6E-39 T 28-03-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 ALX04_RS05270 1e7e0be2f298de004efe870be2f13dc9 163 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 85 101 1.6E-39 T 28-03-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 ALX04_RS05270 1e7e0be2f298de004efe870be2f13dc9 163 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 20 41 1.6E-39 T 28-03-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 ALX04_RS05270 1e7e0be2f298de004efe870be2f13dc9 163 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 112 134 1.6E-39 T 28-03-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 ALX04_RS05270 1e7e0be2f298de004efe870be2f13dc9 163 Gene3D G3DSA:3.40.50.620 1 158 2.8E-35 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold ALX04_RS05270 1e7e0be2f298de004efe870be2f13dc9 163 SUPERFAMILY SSF52374 1 156 1.1E-41 T 28-03-2018 ALX04_RS05270 1e7e0be2f298de004efe870be2f13dc9 163 TIGRFAM TIGR01510 coaD_prev_kdtB: pantetheine-phosphate adenylyltransferase 3 156 6.8E-58 T 28-03-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 ALX04_RS05270 1e7e0be2f298de004efe870be2f13dc9 163 Pfam PF01467 Cytidylyltransferase-like 5 133 1.7E-15 T 28-03-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 ALX04_RS05270 1e7e0be2f298de004efe870be2f13dc9 163 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 4 62 2.1E-16 T 28-03-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 ALX04_RS07615 f4a7b639bbed1528ac2825aee5a1169b 300 Gene3D G3DSA:3.30.2350.10 83 295 6.1E-59 T 28-03-2018 ALX04_RS07615 f4a7b639bbed1528ac2825aee5a1169b 300 Pfam PF00849 RNA pseudouridylate synthase 92 242 6.7E-31 T 28-03-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 ALX04_RS07615 f4a7b639bbed1528ac2825aee5a1169b 300 ProSitePatterns PS01129 Rlu family of pseudouridine synthase signature. 133 147 - T 28-03-2018 IPR006224 Pseudouridine synthase, RluC/RluD, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0009982 ALX04_RS07615 f4a7b639bbed1528ac2825aee5a1169b 300 SUPERFAMILY SSF55120 80 291 2.08E-58 T 28-03-2018 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 ALX04_RS02210 df6fe5a4cb42b8a76bb0fafbff89953b 245 SUPERFAMILY SSF52540 3 224 6.46E-58 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase ALX04_RS02210 df6fe5a4cb42b8a76bb0fafbff89953b 245 Pfam PF00005 ABC transporter 18 161 5.8E-31 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 ALX04_RS02210 df6fe5a4cb42b8a76bb0fafbff89953b 245 SMART SM00382 27 209 1.7E-8 T 28-03-2018 IPR003593 AAA+ ATPase domain ALX04_RS02210 df6fe5a4cb42b8a76bb0fafbff89953b 245 Gene3D G3DSA:3.40.50.300 1 232 1.6E-58 T 28-03-2018 ALX04_RS02210 df6fe5a4cb42b8a76bb0fafbff89953b 245 ProSitePatterns PS00211 ABC transporters family signature. 134 148 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 ALX04_RS05845 1d9a81d3023926de784c029e3496c36d 202 Gene3D G3DSA:3.60.21.10 3 198 2.4E-20 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like ALX04_RS05845 1d9a81d3023926de784c029e3496c36d 202 Pfam PF12850 Calcineurin-like phosphoesterase superfamily domain 6 159 1.7E-7 T 28-03-2018 IPR024654 Calcineurin-like phosphoesterase domain, lpxH type Reactome: R-HSA-3238698 ALX04_RS05845 1d9a81d3023926de784c029e3496c36d 202 SUPERFAMILY SSF56300 4 162 4.43E-20 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like ALX04_RS05625 58456b9ca3ee6d22a21c282c245110eb 212 SUPERFAMILY SSF110395 3 210 1.44E-59 T 28-03-2018 IPR023648 Copper homeostasis CutC domain GO:0005507|GO:0055070 Reactome: R-HSA-936837 ALX04_RS05625 58456b9ca3ee6d22a21c282c245110eb 212 Gene3D G3DSA:3.20.20.380 1 211 3.2E-71 T 28-03-2018 ALX04_RS05625 58456b9ca3ee6d22a21c282c245110eb 212 Pfam PF03932 CutC family 3 209 1.0E-67 T 28-03-2018 IPR023648 Copper homeostasis CutC domain GO:0005507|GO:0055070 Reactome: R-HSA-936837 ALX04_RS00750 90366b38894578db7ef0d3c15d85c403 178 Pfam PF03802 Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase 12 171 4.3E-51 T 28-03-2018 IPR005551 Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase GO:0051191 ALX04_RS00750 90366b38894578db7ef0d3c15d85c403 178 TIGRFAM TIGR03124 citrate_citX: holo-ACP synthase CitX 12 172 4.5E-56 T 28-03-2018 IPR005551 Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase GO:0051191 ALX04_RS15445 b34b387fe2b34e1612ace888b9ab003c 164 Gene3D G3DSA:3.40.35.10 2 159 5.1E-39 T 28-03-2018 IPR004720 Phosphotransferase system, sorbose subfamily IIB component GO:0005737|GO:0008982|GO:0009401 ALX04_RS15445 b34b387fe2b34e1612ace888b9ab003c 164 SUPERFAMILY SSF52728 1 163 2.75E-38 T 28-03-2018 IPR004720 Phosphotransferase system, sorbose subfamily IIB component GO:0005737|GO:0008982|GO:0009401 ALX04_RS15445 b34b387fe2b34e1612ace888b9ab003c 164 Pfam PF03830 PTS system sorbose subfamily IIB component 3 150 2.3E-34 T 28-03-2018 IPR004720 Phosphotransferase system, sorbose subfamily IIB component GO:0005737|GO:0008982|GO:0009401 ALX04_RS13160 8a0f13c7e35a39899f62ddf43fab1a38 306 Gene3D G3DSA:3.90.245.10 1 302 3.7E-94 T 28-03-2018 IPR001910 Inosine/uridine-preferring nucleoside hydrolase domain ALX04_RS13160 8a0f13c7e35a39899f62ddf43fab1a38 306 Pfam PF01156 Inosine-uridine preferring nucleoside hydrolase 4 292 1.0E-78 T 28-03-2018 IPR001910 Inosine/uridine-preferring nucleoside hydrolase domain ALX04_RS13160 8a0f13c7e35a39899f62ddf43fab1a38 306 SUPERFAMILY SSF53590 3 299 2.35E-91 T 28-03-2018 IPR001910 Inosine/uridine-preferring nucleoside hydrolase domain ALX04_RS02435 6a8c3c5a0828449257d1988e27d06040 184 Pfam PF02620 Uncharacterized ACR, COG1399 57 176 8.8E-21 T 28-03-2018 IPR003772 Large ribosomal RNA subunit accumulation protein YceD ALX04_RS10925 ac8af4d1cd6ecd6db382a35b572a50b4 445 Pfam PF09967 VWA-like domain (DUF2201) 311 440 9.8E-10 T 28-03-2018 IPR018698 VWA-like domain ALX04_RS10925 ac8af4d1cd6ecd6db382a35b572a50b4 445 Pfam PF13203 Putative metallopeptidase domain 32 295 1.4E-10 T 28-03-2018 IPR025154 Putative metallopeptidase domain ALX04_RS06745 e816be2d3507c89c5719ff229400c6bd 125 Pfam PF05866 Endodeoxyribonuclease RusA 11 118 8.3E-5 T 28-03-2018 IPR008822 Crossover junction endodeoxyribonuclease, RusA-like GO:0000287|GO:0006281|GO:0006310 ALX04_RS06745 e816be2d3507c89c5719ff229400c6bd 125 SUPERFAMILY SSF103084 4 118 3.53E-22 T 28-03-2018 IPR008822 Crossover junction endodeoxyribonuclease, RusA-like GO:0000287|GO:0006281|GO:0006310 ALX04_RS06745 e816be2d3507c89c5719ff229400c6bd 125 Gene3D G3DSA:3.30.1330.70 1 122 5.6E-16 T 28-03-2018 IPR008822 Crossover junction endodeoxyribonuclease, RusA-like GO:0000287|GO:0006281|GO:0006310 ALX04_RS11485 09b77412ed727f24ff13df9e7d4aa992 178 SUPERFAMILY SSF50814 3 177 3.79E-80 T 28-03-2018 IPR012674 Calycin ALX04_RS11485 09b77412ed727f24ff13df9e7d4aa992 178 Gene3D G3DSA:2.40.128.20 9 161 5.3E-63 T 28-03-2018 IPR012674 Calycin ALX04_RS11485 09b77412ed727f24ff13df9e7d4aa992 178 ProDom PD022010 DECARBOXYLASE ACID PHENOLIC P-COUMARIC LYASE 4.1.1.- PAD PADC FERULATE PROBABLE 8 167 7.0E-92 T 28-03-2018 IPR008729 Phenolic acid decarboxylase, bacterial GO:0016831 ALX04_RS11485 09b77412ed727f24ff13df9e7d4aa992 178 Pfam PF05870 Phenolic acid decarboxylase (PAD) 8 165 9.3E-80 T 28-03-2018 IPR008729 Phenolic acid decarboxylase, bacterial GO:0016831 ALX04_RS11485 09b77412ed727f24ff13df9e7d4aa992 178 PIRSF PIRSF011561 1 178 3.1E-104 T 28-03-2018 IPR008729 Phenolic acid decarboxylase, bacterial GO:0016831 ALX04_RS02835 8320e59930a881b19de2758eb06258b3 61 Pfam PF00830 Ribosomal L28 family 3 57 7.6E-19 T 28-03-2018 IPR026569 Ribosomal protein L28/L24 GO:0003735 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 ALX04_RS02835 8320e59930a881b19de2758eb06258b3 61 Gene3D G3DSA:2.30.170.40 2 60 1.9E-17 T 28-03-2018 IPR026569 Ribosomal protein L28/L24 GO:0003735 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 ALX04_RS02835 8320e59930a881b19de2758eb06258b3 61 TIGRFAM TIGR00009 L28: ribosomal protein bL28 1 55 5.2E-20 T 28-03-2018 IPR001383 Ribosomal protein L28 GO:0003735|GO:0005622|GO:0005840|GO:0006412 ALX04_RS02835 8320e59930a881b19de2758eb06258b3 61 Hamap MF_00373 50S ribosomal protein L28 [rpmB]. 1 61 16.691 T 28-03-2018 IPR001383 Ribosomal protein L28 GO:0003735|GO:0005622|GO:0005840|GO:0006412 ALX04_RS02835 8320e59930a881b19de2758eb06258b3 61 SUPERFAMILY SSF143800 2 60 3.92E-21 T 28-03-2018 IPR034704 L28p-like Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 ALX04_RS10625 ac7df745fe47ebaa3e609b272436e2a5 407 SUPERFAMILY SSF103473 9 399 6.8E-71 T 28-03-2018 IPR020846 Major facilitator superfamily domain ALX04_RS10625 ac7df745fe47ebaa3e609b272436e2a5 407 Gene3D G3DSA:1.20.1250.20 206 404 7.7E-30 T 28-03-2018 ALX04_RS10625 ac7df745fe47ebaa3e609b272436e2a5 407 Pfam PF00083 Sugar (and other) transporter 252 396 3.6E-7 T 28-03-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 ALX04_RS10625 ac7df745fe47ebaa3e609b272436e2a5 407 PRINTS PR01035 Tetracycline resistance protein signature 140 162 5.5E-8 T 28-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 ALX04_RS10625 ac7df745fe47ebaa3e609b272436e2a5 407 PRINTS PR01035 Tetracycline resistance protein signature 110 131 5.5E-8 T 28-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 ALX04_RS10625 ac7df745fe47ebaa3e609b272436e2a5 407 PRINTS PR01035 Tetracycline resistance protein signature 21 37 5.5E-8 T 28-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 ALX04_RS10625 ac7df745fe47ebaa3e609b272436e2a5 407 PRINTS PR01035 Tetracycline resistance protein signature 83 107 5.5E-8 T 28-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 ALX04_RS10625 ac7df745fe47ebaa3e609b272436e2a5 407 Pfam PF07690 Major Facilitator Superfamily 15 247 2.3E-36 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 ALX04_RS10625 ac7df745fe47ebaa3e609b272436e2a5 407 Gene3D G3DSA:1.20.1250.20 5 205 3.6E-34 T 28-03-2018 ALX04_RS10265 f81704b45c2e81e3eee59269e5029741 102 SUPERFAMILY SSF103481 6 101 4.97E-17 T 28-03-2018 ALX04_RS10265 f81704b45c2e81e3eee59269e5029741 102 Pfam PF00893 Small Multidrug Resistance protein 1 91 7.5E-21 T 28-03-2018 IPR000390 Small multidrug resistance protein family GO:0016021 ALX04_RS05290 455b58a9b3a1601132915ab82fcbbb07 388 Pfam PF01098 Cell cycle protein 12 375 2.4E-94 T 28-03-2018 IPR001182 Probable peptidoglycan glycosyltransferase FtsW/RodA GO:0016021|GO:0051301 ALX04_RS05290 455b58a9b3a1601132915ab82fcbbb07 388 ProSitePatterns PS00428 Cell cycle proteins ftsW / rodA / spoVE signature. 334 358 - T 28-03-2018 IPR018365 Cell cycle, FtsW / RodA / SpoVE, conserved site GO:0007049|GO:0016021 ALX04_RS11535 921badd77f5b5f51d85e4d2934f9344e 245 Pfam PF13731 WxL domain surface cell wall-binding 40 243 1.8E-45 T 28-03-2018 IPR027994 WxL domain ALX04_RS09205 68adbaa96f9134992dc658edf7041325 273 Pfam PF01381 Helix-turn-helix 12 67 9.6E-11 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 ALX04_RS09205 68adbaa96f9134992dc658edf7041325 273 SMART SM00530 11 67 1.8E-11 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 ALX04_RS09205 68adbaa96f9134992dc658edf7041325 273 SUPERFAMILY SSF47413 5 71 7.32E-14 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 ALX04_RS09205 68adbaa96f9134992dc658edf7041325 273 Gene3D G3DSA:1.10.3100.10 1 262 5.8E-17 T 28-03-2018 IPR027910 YdiL-like domain ALX04_RS07780 68d3cc57c38d90dec8a3f9c592ad6dec 213 Gene3D G3DSA:3.40.50.720 1 213 6.0E-29 T 28-03-2018 ALX04_RS07780 68d3cc57c38d90dec8a3f9c592ad6dec 213 Pfam PF13460 NAD(P)H-binding 7 190 5.9E-42 T 28-03-2018 IPR016040 NAD(P)-binding domain ALX04_RS07780 68d3cc57c38d90dec8a3f9c592ad6dec 213 SUPERFAMILY SSF51735 1 204 1.58E-38 T 28-03-2018 IPR016040 NAD(P)-binding domain ALX04_RS00600 d4e66e426f9cf43eedeefe3777e79b3d 297 Gene3D G3DSA:3.40.50.10860 1 116 2.4E-36 T 28-03-2018 ALX04_RS00600 d4e66e426f9cf43eedeefe3777e79b3d 297 SUPERFAMILY SSF51735 106 284 4.44E-37 T 28-03-2018 IPR016040 NAD(P)-binding domain ALX04_RS00600 d4e66e426f9cf43eedeefe3777e79b3d 297 TIGRFAM TIGR00507 aroE: shikimate dehydrogenase 8 286 7.5E-66 T 28-03-2018 IPR011342 Shikimate dehydrogenase GO:0004764|GO:0019632|GO:0050661|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163 ALX04_RS00600 d4e66e426f9cf43eedeefe3777e79b3d 297 Gene3D G3DSA:3.40.50.720 117 290 2.0E-30 T 28-03-2018 ALX04_RS00600 d4e66e426f9cf43eedeefe3777e79b3d 297 SUPERFAMILY SSF53223 1 105 4.95E-31 T 28-03-2018 ALX04_RS00600 d4e66e426f9cf43eedeefe3777e79b3d 297 Hamap MF_00222 Shikimate dehydrogenase (NADP(+)) [aroE]. 6 285 31.723 T 28-03-2018 IPR022893 Shikimate dehydrogenase family GO:0004764|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163 ALX04_RS00600 d4e66e426f9cf43eedeefe3777e79b3d 297 Pfam PF08501 Shikimate dehydrogenase substrate binding domain 12 93 2.6E-24 T 28-03-2018 IPR013708 Shikimate dehydrogenase substrate binding, N-terminal GO:0004764|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163 ALX04_RS05265 55221f8849acb8b9d0b6fabd48e6c892 348 Pfam PF05362 Lon protease (S16) C-terminal proteolytic domain 203 296 3.7E-9 T 28-03-2018 IPR008269 Peptidase S16, Lon proteolytic domain GO:0004176|GO:0004252|GO:0006508 ALX04_RS05265 55221f8849acb8b9d0b6fabd48e6c892 348 SUPERFAMILY SSF50156 132 212 1.97E-13 T 28-03-2018 IPR001478 PDZ domain GO:0005515 ALX04_RS05265 55221f8849acb8b9d0b6fabd48e6c892 348 Pfam PF13180 PDZ domain 132 196 7.6E-11 T 28-03-2018 IPR001478 PDZ domain GO:0005515 ALX04_RS05265 55221f8849acb8b9d0b6fabd48e6c892 348 SUPERFAMILY SSF54211 203 344 4.55E-21 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold ALX04_RS05265 55221f8849acb8b9d0b6fabd48e6c892 348 Gene3D G3DSA:3.30.230.10 36 348 5.0E-37 T 28-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup ALX04_RS03680 7b457a8adc6589e767367eaf88399fd1 373 SUPERFAMILY SSF53756 64 368 3.35E-14 T 28-03-2018 ALX04_RS03680 7b457a8adc6589e767367eaf88399fd1 373 Pfam PF04464 CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase 19 366 3.5E-50 T 28-03-2018 IPR007554 CDP-glycerol glycerophosphotransferase GO:0016020|GO:0047355 ALX04_RS01380 939910cb4212928bcf1c5295cd8231ed 359 Gene3D G3DSA:3.40.50.300 4 334 1.9E-79 T 28-03-2018 ALX04_RS01380 939910cb4212928bcf1c5295cd8231ed 359 Pfam PF00005 ABC transporter 28 185 3.9E-28 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 ALX04_RS01380 939910cb4212928bcf1c5295cd8231ed 359 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 237 299 1.3E-12 T 28-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 ALX04_RS01380 939910cb4212928bcf1c5295cd8231ed 359 ProSitePatterns PS00211 ABC transporters family signature. 158 172 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 ALX04_RS01380 939910cb4212928bcf1c5295cd8231ed 359 SUPERFAMILY SSF52540 7 256 1.1E-71 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase ALX04_RS01380 939910cb4212928bcf1c5295cd8231ed 359 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 235 320 1.0E-18 T 28-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 ALX04_RS01380 939910cb4212928bcf1c5295cd8231ed 359 SMART SM00382 36 235 2.4E-17 T 28-03-2018 IPR003593 AAA+ ATPase domain ALX04_RS04200 806a4681ef3dbe9dc509813674733264 237 Pfam PF01418 Helix-turn-helix domain, rpiR family 6 71 1.1E-14 T 28-03-2018 IPR000281 Helix-turn-helix protein RpiR GO:0003700|GO:0006355 ALX04_RS04200 806a4681ef3dbe9dc509813674733264 237 Gene3D G3DSA:3.40.50.10490 70 236 7.4E-24 T 28-03-2018 ALX04_RS04200 806a4681ef3dbe9dc509813674733264 237 SUPERFAMILY SSF46689 5 71 2.87E-18 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 ALX04_RS04200 806a4681ef3dbe9dc509813674733264 237 Gene3D G3DSA:1.10.10.10 4 69 1.1E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS04200 806a4681ef3dbe9dc509813674733264 237 SUPERFAMILY SSF53697 85 230 1.98E-27 T 28-03-2018 ALX04_RS04200 806a4681ef3dbe9dc509813674733264 237 Pfam PF01380 SIS domain 108 208 6.8E-13 T 28-03-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 ALX04_RS02025 93a4b748f1e1bd25b98a82bc1105dc23 406 SUPERFAMILY SSF56300 1 261 8.11E-46 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like ALX04_RS02025 93a4b748f1e1bd25b98a82bc1105dc23 406 Pfam PF00149 Calcineurin-like phosphoesterase 1 196 1.4E-12 T 28-03-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 ALX04_RS02025 93a4b748f1e1bd25b98a82bc1105dc23 406 Gene3D G3DSA:3.60.21.10 1 75 3.9E-13 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like ALX04_RS02025 93a4b748f1e1bd25b98a82bc1105dc23 406 Gene3D G3DSA:3.60.21.10 76 246 7.4E-17 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like ALX04_RS02025 93a4b748f1e1bd25b98a82bc1105dc23 406 PIRSF PIRSF033091 1 406 2.9E-130 T 28-03-2018 IPR014576 Predicted phosphoesterase, YhaO type ALX04_RS05170 b2178da01478297d3857005704452f5f 246 Pfam PF00005 ABC transporter 21 170 2.9E-36 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 ALX04_RS05170 b2178da01478297d3857005704452f5f 246 Gene3D G3DSA:3.40.50.300 2 245 4.8E-79 T 28-03-2018 ALX04_RS05170 b2178da01478297d3857005704452f5f 246 PIRSF PIRSF039085 2 246 4.4E-114 T 28-03-2018 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 ALX04_RS05170 b2178da01478297d3857005704452f5f 246 SMART SM00382 30 225 3.1E-12 T 28-03-2018 IPR003593 AAA+ ATPase domain ALX04_RS05170 b2178da01478297d3857005704452f5f 246 ProSitePatterns PS00211 ABC transporters family signature. 142 156 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 ALX04_RS05170 b2178da01478297d3857005704452f5f 246 SUPERFAMILY SSF52540 5 240 3.34E-82 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase ALX04_RS10880 b711f71bddccea61ed1a027190c04672 157 SUPERFAMILY SSF55729 36 145 9.75E-9 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase ALX04_RS10880 b711f71bddccea61ed1a027190c04672 157 Gene3D G3DSA:3.40.630.30 1 157 4.0E-5 T 28-03-2018 ALX04_RS10880 b711f71bddccea61ed1a027190c04672 157 Pfam PF13302 Acetyltransferase (GNAT) domain 35 137 8.7E-6 T 28-03-2018 IPR000182 GNAT domain GO:0008080 ALX04_RS15150 c04e866029550f7a9a48abfe4b15a21d 213 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 10 106 1.7E-23 T 28-03-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 ALX04_RS15150 c04e866029550f7a9a48abfe4b15a21d 213 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 31 211 1.0E-26 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 ALX04_RS15150 c04e866029550f7a9a48abfe4b15a21d 213 SUPERFAMILY SSF161098 9 200 8.5E-50 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 ALX04_RS15150 c04e866029550f7a9a48abfe4b15a21d 213 Gene3D G3DSA:1.10.3720.10 2 213 1.5E-47 T 28-03-2018 ALX04_RS14075 36c0d97cb8d19bc5825408410c0002ff 275 Gene3D G3DSA:3.40.50.620 3 275 4.9E-56 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold ALX04_RS14075 36c0d97cb8d19bc5825408410c0002ff 275 Hamap MF_00193 NH(3)-dependent NAD(+) synthetase [nadE]. 18 269 28.717 T 28-03-2018 IPR022926 NH(3)-dependent NAD(+) synthetase GO:0008795|GO:0009435 KEGG: 00760+6.3.1.5 ALX04_RS14075 36c0d97cb8d19bc5825408410c0002ff 275 SUPERFAMILY SSF52402 4 274 7.24E-79 T 28-03-2018 ALX04_RS14075 36c0d97cb8d19bc5825408410c0002ff 275 Pfam PF02540 NAD synthase 24 265 1.7E-64 T 28-03-2018 IPR022310 NAD/GMP synthase ALX04_RS14075 36c0d97cb8d19bc5825408410c0002ff 275 TIGRFAM TIGR00552 nadE: NAD+ synthetase 20 275 1.2E-67 T 28-03-2018 IPR003694 NAD(+) synthetase GO:0003952|GO:0005524|GO:0009435 KEGG: 00760+6.3.1.5|Reactome: R-HSA-196807 ALX04_RS10905 360b0258115942d31126c0f8cd41855d 190 Pfam PF13731 WxL domain surface cell wall-binding 39 189 3.5E-22 T 28-03-2018 IPR027994 WxL domain ALX04_RS13410 933a06936ae65a4167318accf76955e0 222 Pfam PF02517 CAAX protease self-immunity 126 212 6.1E-17 T 28-03-2018 IPR003675 CAAX amino terminal protease GO:0016020 Reactome: R-HSA-5689880 ALX04_RS09720 4a79e934858b7b54923ccddf0e0dd3a4 83 Gene3D G3DSA:1.10.10.60 7 83 1.1E-17 T 28-03-2018 ALX04_RS09720 4a79e934858b7b54923ccddf0e0dd3a4 83 Pfam PF01527 Transposase 2 76 5.8E-12 T 28-03-2018 IPR002514 Transposase IS3/IS911family GO:0003677|GO:0004803|GO:0006313 ALX04_RS09720 4a79e934858b7b54923ccddf0e0dd3a4 83 SUPERFAMILY SSF46689 1 82 1.52E-17 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 ALX04_RS04190 cc7a41321bce393472647b88c75262df 210 Pfam PF13419 Haloacid dehalogenase-like hydrolase 5 176 1.7E-30 T 28-03-2018 IPR023214 HAD-like domain ALX04_RS04190 cc7a41321bce393472647b88c75262df 210 SUPERFAMILY SSF56784 1 206 9.29E-35 T 28-03-2018 IPR023214 HAD-like domain ALX04_RS04190 cc7a41321bce393472647b88c75262df 210 Gene3D G3DSA:3.40.50.1000 2 193 1.7E-22 T 28-03-2018 IPR023214 HAD-like domain ALX04_RS05980 2b90cd634e0cac839b079c2cd4b2c6e8 227 Gene3D G3DSA:3.30.1380.20 60 173 4.6E-17 T 28-03-2018 ALX04_RS05980 2b90cd634e0cac839b079c2cd4b2c6e8 227 SUPERFAMILY SSF111126 66 172 6.8E-19 T 28-03-2018 IPR024096 NO signalling/Golgi transport ligand-binding domain ALX04_RS05980 2b90cd634e0cac839b079c2cd4b2c6e8 227 Pfam PF10702 Protein of unknown function (DUF2507) 73 192 1.7E-39 T 28-03-2018 IPR019642 Protein of unknown function DUF2507 ALX04_RS11755 9b7833ba6ebe034d23da1e799b36219c 476 Gene3D G3DSA:3.40.309.10 235 423 8.5E-46 T 28-03-2018 ALX04_RS11755 9b7833ba6ebe034d23da1e799b36219c 476 SUPERFAMILY SSF53720 3 446 6.41E-100 T 28-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 ALX04_RS11755 9b7833ba6ebe034d23da1e799b36219c 476 Gene3D G3DSA:3.40.605.10 2 234 1.5E-54 T 28-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 ALX04_RS11755 9b7833ba6ebe034d23da1e799b36219c 476 Pfam PF00171 Aldehyde dehydrogenase family 9 444 1.1E-79 T 28-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 ALX04_RS11755 9b7833ba6ebe034d23da1e799b36219c 476 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 215 222 - T 28-03-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 ALX04_RS11755 9b7833ba6ebe034d23da1e799b36219c 476 PIRSF PIRSF036492 1 475 1.9E-140 T 28-03-2018 IPR012394 Aldehyde dehydrogenase NAD(P)-dependent GO:0004030|GO:0006081|GO:0055114 ALX04_RS11415 6f54f0dfd15166a51a65909a122bd263 603 SUPERFAMILY SSF52467 194 365 3.27E-41 T 28-03-2018 IPR029035 DHS-like NAD/FAD-binding domain ALX04_RS11415 6f54f0dfd15166a51a65909a122bd263 603 TIGRFAM TIGR02720 pyruv_oxi_spxB: pyruvate oxidase 13 588 0.0 T 28-03-2018 IPR014092 Pyruvate oxidase GO:0047112|GO:0055114 KEGG: 00620+1.2.3.3 ALX04_RS11415 6f54f0dfd15166a51a65909a122bd263 603 Gene3D G3DSA:3.40.50.1220 193 351 5.0E-39 T 28-03-2018 IPR029035 DHS-like NAD/FAD-binding domain ALX04_RS11415 6f54f0dfd15166a51a65909a122bd263 603 ProSitePatterns PS00187 Thiamine pyrophosphate enzymes signature. 430 449 - T 28-03-2018 IPR000399 TPP-binding enzyme, conserved site GO:0000287|GO:0030976 ALX04_RS11415 6f54f0dfd15166a51a65909a122bd263 603 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 393 542 7.9E-36 T 28-03-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 ALX04_RS11415 6f54f0dfd15166a51a65909a122bd263 603 SUPERFAMILY SSF52518 368 588 1.43E-55 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold ALX04_RS11415 6f54f0dfd15166a51a65909a122bd263 603 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 203 332 1.6E-30 T 28-03-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 ALX04_RS11415 6f54f0dfd15166a51a65909a122bd263 603 Gene3D G3DSA:3.40.50.970 1 192 5.3E-44 T 28-03-2018 ALX04_RS11415 6f54f0dfd15166a51a65909a122bd263 603 SUPERFAMILY SSF52518 2 182 1.52E-45 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold ALX04_RS11415 6f54f0dfd15166a51a65909a122bd263 603 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 14 180 2.7E-43 T 28-03-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 ALX04_RS11415 6f54f0dfd15166a51a65909a122bd263 603 Gene3D G3DSA:3.40.50.970 352 556 4.3E-32 T 28-03-2018 ALX04_RS09010 72daab6479b512298462fd6ccd06406f 233 Gene3D G3DSA:3.40.50.1110 40 230 3.1E-17 T 28-03-2018 ALX04_RS09010 72daab6479b512298462fd6ccd06406f 233 SUPERFAMILY SSF52266 74 223 8.49E-13 T 28-03-2018 IPR013830 SGNH hydrolase-type esterase domain ALX04_RS04405 6bea0bc8a3ab0ded51d8dbe1e7948ce0 291 PIRSF PIRSF006483 1 291 1.0E-94 T 28-03-2018 IPR003740 Uncharacterised membrane protein YitT ALX04_RS04405 6bea0bc8a3ab0ded51d8dbe1e7948ce0 291 Pfam PF10035 Uncharacterized protein conserved in bacteria (DUF2179) 229 284 2.2E-19 T 28-03-2018 IPR019264 Domain of unknown function DUF2179 ALX04_RS04405 6bea0bc8a3ab0ded51d8dbe1e7948ce0 291 Pfam PF02588 Uncharacterised 5xTM membrane BCR, YitT family COG1284 20 222 6.6E-59 T 28-03-2018 IPR003740 Uncharacterised membrane protein YitT ALX04_RS05555 153f2b87566a582c74bc28a02608478f 141 ProDom PD006745 MRAZ YABB DIVISION CELL 3D-STRUCTURE UNCHARACTERIZED BCR SIMILAR PROTEIN 1 138 2.0E-68 T 28-03-2018 IPR003444 Transcriptional regulator MraZ GO:0003700|GO:0006355 ALX04_RS05555 153f2b87566a582c74bc28a02608478f 141 Gene3D G3DSA:2.10.260.10 74 122 1.2E-8 T 28-03-2018 ALX04_RS05555 153f2b87566a582c74bc28a02608478f 141 Gene3D G3DSA:2.10.260.10 1 65 3.8E-6 T 28-03-2018 ALX04_RS05555 153f2b87566a582c74bc28a02608478f 141 TIGRFAM TIGR00242 TIGR00242: division/cell wall cluster transcriptional repressor MraZ 1 141 1.9E-48 T 28-03-2018 IPR003444 Transcriptional regulator MraZ GO:0003700|GO:0006355 ALX04_RS05555 153f2b87566a582c74bc28a02608478f 141 Hamap MF_01008 Transcriptional regulator MraZ [mraZ]. 1 141 56.181 T 28-03-2018 IPR003444 Transcriptional regulator MraZ GO:0003700|GO:0006355 ALX04_RS05555 153f2b87566a582c74bc28a02608478f 141 Pfam PF02381 MraZ protein, putative antitoxin-like 1 70 3.9E-20 T 28-03-2018 IPR020603 MraZ domain ALX04_RS05555 153f2b87566a582c74bc28a02608478f 141 Pfam PF02381 MraZ protein, putative antitoxin-like 72 140 2.0E-24 T 28-03-2018 IPR020603 MraZ domain ALX04_RS05555 153f2b87566a582c74bc28a02608478f 141 SUPERFAMILY SSF89447 1 136 1.5E-51 T 28-03-2018 ALX04_RS05515 978aedd2af4adfe8d228d85ec9220a99 448 PIRSF PIRSF003101 1 447 9.9E-152 T 28-03-2018 IPR020823 Cell division protein FtsA GO:0007049 ALX04_RS05515 978aedd2af4adfe8d228d85ec9220a99 448 Hamap MF_02033 Cell division protein FtsA [ftsA]. 3 447 28.46 T 28-03-2018 IPR020823 Cell division protein FtsA GO:0007049 ALX04_RS05515 978aedd2af4adfe8d228d85ec9220a99 448 Gene3D G3DSA:3.30.420.40 285 385 2.1E-5 T 28-03-2018 ALX04_RS05515 978aedd2af4adfe8d228d85ec9220a99 448 SUPERFAMILY SSF53067 5 195 1.13E-57 T 28-03-2018 ALX04_RS05515 978aedd2af4adfe8d228d85ec9220a99 448 SUPERFAMILY SSF53067 197 358 6.48E-38 T 28-03-2018 ALX04_RS05515 978aedd2af4adfe8d228d85ec9220a99 448 Pfam PF02491 SHS2 domain inserted in FTSA 84 158 9.8E-24 T 28-03-2018 IPR003494 SHS2 domain inserted in FtsA GO:0005515|GO:0007049 ALX04_RS05515 978aedd2af4adfe8d228d85ec9220a99 448 Gene3D G3DSA:3.30.1490.110 102 163 2.3E-25 T 28-03-2018 ALX04_RS05515 978aedd2af4adfe8d228d85ec9220a99 448 Gene3D G3DSA:3.90.640.10 247 284 3.7E-21 T 28-03-2018 ALX04_RS05515 978aedd2af4adfe8d228d85ec9220a99 448 Gene3D G3DSA:3.30.420.40 195 246 5.7E-4 T 28-03-2018 ALX04_RS05515 978aedd2af4adfe8d228d85ec9220a99 448 Pfam PF14450 Cell division protein FtsA 205 365 7.0E-19 T 28-03-2018 ALX04_RS05515 978aedd2af4adfe8d228d85ec9220a99 448 SMART SM00842 7 194 5.8E-91 T 28-03-2018 IPR003494 SHS2 domain inserted in FtsA GO:0005515|GO:0007049 ALX04_RS05515 978aedd2af4adfe8d228d85ec9220a99 448 Gene3D G3DSA:3.30.420.40 1 101 1.8E-9 T 28-03-2018 ALX04_RS05515 978aedd2af4adfe8d228d85ec9220a99 448 Pfam PF11983 Membrane-attachment and polymerisation-promoting switch 377 448 3.9E-8 T 28-03-2018 IPR021873 Cell division protein FtsA, C-terminal ALX04_RS05515 978aedd2af4adfe8d228d85ec9220a99 448 TIGRFAM TIGR01174 ftsA: cell division protein FtsA 7 360 3.5E-101 T 28-03-2018 IPR020823 Cell division protein FtsA GO:0007049 ALX04_RS05140 4266ec77295dc085677658428c5510f0 221 TIGRFAM TIGR03025 EPS_sugtrans: exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase 24 221 1.2E-91 T 28-03-2018 IPR017475 Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase ALX04_RS05140 4266ec77295dc085677658428c5510f0 221 Pfam PF02397 Bacterial sugar transferase 35 215 6.7E-68 T 28-03-2018 IPR003362 Bacterial sugar transferase ALX04_RS05970 bd0b0fbad9f1f0267d477ba1af570679 202 Gene3D G3DSA:3.90.950.10 1 199 1.2E-73 T 28-03-2018 IPR029001 Inosine triphosphate pyrophosphatase-like ALX04_RS05970 bd0b0fbad9f1f0267d477ba1af570679 202 SUPERFAMILY SSF52972 4 196 4.45E-65 T 28-03-2018 IPR029001 Inosine triphosphate pyrophosphatase-like ALX04_RS05970 bd0b0fbad9f1f0267d477ba1af570679 202 Hamap MF_01405 dITP/XTP pyrophosphatase [rdgB]. 5 197 49.329 T 28-03-2018 IPR020922 dITP/XTP pyrophosphatase GO:0009143|GO:0017111 ALX04_RS05970 bd0b0fbad9f1f0267d477ba1af570679 202 TIGRFAM TIGR00042 TIGR00042: non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family 7 194 1.9E-53 T 28-03-2018 IPR002637 Ham1-like protein GO:0009143|GO:0047429 Reactome: R-HSA-74259 ALX04_RS05970 bd0b0fbad9f1f0267d477ba1af570679 202 Pfam PF01725 Ham1 family 7 192 7.9E-54 T 28-03-2018 IPR002637 Ham1-like protein GO:0009143|GO:0047429 Reactome: R-HSA-74259 ALX04_RS02560 650e32384d874e0a2d1506b937987b1f 151 SMART SM00850 50 146 1.7E-20 T 28-03-2018 IPR007492 LytTR DNA-binding domain GO:0003677 ALX04_RS02560 650e32384d874e0a2d1506b937987b1f 151 Pfam PF04397 LytTr DNA-binding domain 51 142 3.7E-17 T 28-03-2018 IPR007492 LytTR DNA-binding domain GO:0003677 ALX04_RS02560 650e32384d874e0a2d1506b937987b1f 151 Gene3D G3DSA:2.40.50.40 40 109 7.3E-13 T 28-03-2018 ALX04_RS06115 72567d1c64c46237ea2b47a388073a92 194 PIRSF PIRSF000847 1 194 2.6E-46 T 28-03-2018 IPR004570 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase GO:0008444|GO:0008654|GO:0016021 KEGG: 00564+2.7.8.5|MetaCyc: PWY-5269|MetaCyc: PWY-5668|MetaCyc: PWY-7817 ALX04_RS06115 72567d1c64c46237ea2b47a388073a92 194 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 59 81 - T 28-03-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 ALX04_RS06115 72567d1c64c46237ea2b47a388073a92 194 Pfam PF01066 CDP-alcohol phosphatidyltransferase 2 81 1.5E-14 T 28-03-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 ALX04_RS06115 72567d1c64c46237ea2b47a388073a92 194 TIGRFAM TIGR00560 pgsA: CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase 2 187 7.6E-49 T 28-03-2018 IPR004570 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase GO:0008444|GO:0008654|GO:0016021 KEGG: 00564+2.7.8.5|MetaCyc: PWY-5269|MetaCyc: PWY-5668|MetaCyc: PWY-7817 ALX04_RS07355 1e0832b1066412389b8e332010b2210a 353 PIRSF PIRSF000148 3 350 6.3E-122 T 28-03-2018 ALX04_RS07355 1e0832b1066412389b8e332010b2210a 353 Pfam PF02774 Semialdehyde dehydrogenase, dimerisation domain 138 331 7.6E-48 T 28-03-2018 IPR012280 Semialdehyde dehydrogenase, dimerisation domain GO:0003942|GO:0005737|GO:0008652|GO:0016620|GO:0046983|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 ALX04_RS07355 1e0832b1066412389b8e332010b2210a 353 TIGRFAM TIGR01296 asd_B: aspartate-semialdehyde dehydrogenase 5 345 1.9E-139 T 28-03-2018 IPR005986 Aspartate-semialdehyde dehydrogenase, beta-type GO:0004073|GO:0009086|GO:0009088|GO:0009089|GO:0009097|GO:0050661|GO:0055114 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 ALX04_RS07355 1e0832b1066412389b8e332010b2210a 353 Hamap MF_02121 Aspartate-semialdehyde dehydrogenase [asd]. 3 345 36.258 T 28-03-2018 IPR012080 Aspartate-semialdehyde dehydrogenase GO:0004073|GO:0009086|GO:0009088|GO:0009089|GO:0009097|GO:0050661|GO:0055114 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 ALX04_RS07355 1e0832b1066412389b8e332010b2210a 353 SUPERFAMILY SSF51735 4 156 2.16E-50 T 28-03-2018 IPR016040 NAD(P)-binding domain ALX04_RS07355 1e0832b1066412389b8e332010b2210a 353 Pfam PF01118 Semialdehyde dehydrogenase, NAD binding domain 5 118 3.3E-35 T 28-03-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 ALX04_RS07355 1e0832b1066412389b8e332010b2210a 353 Gene3D G3DSA:3.40.50.720 2 139 3.9E-34 T 28-03-2018 ALX04_RS07355 1e0832b1066412389b8e332010b2210a 353 SMART SM00859 5 120 5.9E-44 T 28-03-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 ALX04_RS07355 1e0832b1066412389b8e332010b2210a 353 SUPERFAMILY SSF55347 128 332 2.11E-67 T 28-03-2018 ALX04_RS07355 1e0832b1066412389b8e332010b2210a 353 Gene3D G3DSA:3.30.360.10 140 328 4.2E-66 T 28-03-2018 ALX04_RS03435 98ab5e3f9e6446a024b4d26330557b48 135 Pfam PF12680 SnoaL-like domain 16 114 1.2E-8 T 28-03-2018 IPR009959 Polyketide cyclase SnoaL-like domain ALX04_RS03435 98ab5e3f9e6446a024b4d26330557b48 135 Gene3D G3DSA:3.10.450.50 2 126 3.8E-13 T 28-03-2018 ALX04_RS03435 98ab5e3f9e6446a024b4d26330557b48 135 SUPERFAMILY SSF54427 12 121 7.97E-13 T 28-03-2018 IPR032710 NTF2-like domain ALX04_RS13090 c89b161539f3b5e494e6056acd2d6454 180 Pfam PF03551 Transcriptional regulator PadR-like family 6 78 1.1E-10 T 28-03-2018 IPR005149 Transcription regulator PadR, N-terminal ALX04_RS13090 c89b161539f3b5e494e6056acd2d6454 180 SUPERFAMILY SSF46785 3 173 1.14E-29 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS13090 c89b161539f3b5e494e6056acd2d6454 180 Gene3D G3DSA:1.10.10.10 1 91 1.7E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS01270 550daa72f08e694e43466349034b3e35 182 Gene3D G3DSA:2.40.380.10 19 174 2.0E-32 T 28-03-2018 IPR007295 Domain of unknown function DUF402 ALX04_RS01270 550daa72f08e694e43466349034b3e35 182 PIRSF PIRSF028345 5 182 7.6E-74 T 28-03-2018 IPR016882 Uncharacterised protein family UPF0374 ALX04_RS01270 550daa72f08e694e43466349034b3e35 182 SUPERFAMILY SSF159234 8 174 5.75E-32 T 28-03-2018 IPR007295 Domain of unknown function DUF402 ALX04_RS01270 550daa72f08e694e43466349034b3e35 182 Hamap MF_01568 UPF0374 protein . 5 179 47.614 T 28-03-2018 IPR016882 Uncharacterised protein family UPF0374 ALX04_RS01270 550daa72f08e694e43466349034b3e35 182 Pfam PF04167 Protein of unknown function (DUF402) 64 128 1.3E-16 T 28-03-2018 IPR007295 Domain of unknown function DUF402 ALX04_RS03050 a471b8844789e2fb06ddf1be75d9cd56 153 PRINTS PR01071 Acetyl-CoA biotin carboxyl carrier protein signature 95 109 3.3E-11 T 28-03-2018 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 ALX04_RS03050 a471b8844789e2fb06ddf1be75d9cd56 153 PRINTS PR01071 Acetyl-CoA biotin carboxyl carrier protein signature 78 91 3.3E-11 T 28-03-2018 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 ALX04_RS03050 a471b8844789e2fb06ddf1be75d9cd56 153 PRINTS PR01071 Acetyl-CoA biotin carboxyl carrier protein signature 110 123 3.3E-11 T 28-03-2018 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 ALX04_RS03050 a471b8844789e2fb06ddf1be75d9cd56 153 Gene3D G3DSA:2.40.50.100 66 106 2.5E-6 T 28-03-2018 ALX04_RS03050 a471b8844789e2fb06ddf1be75d9cd56 153 Gene3D G3DSA:2.40.50.100 107 151 6.0E-17 T 28-03-2018 ALX04_RS03050 a471b8844789e2fb06ddf1be75d9cd56 153 Pfam PF00364 Biotin-requiring enzyme 76 148 6.0E-20 T 28-03-2018 IPR000089 Biotin/lipoyl attachment ALX04_RS03050 a471b8844789e2fb06ddf1be75d9cd56 153 SUPERFAMILY SSF51230 73 149 1.2E-22 T 28-03-2018 IPR011053 Single hybrid motif ALX04_RS03050 a471b8844789e2fb06ddf1be75d9cd56 153 ProSitePatterns PS00188 Biotin-requiring enzymes attachment site. 105 122 - T 28-03-2018 IPR001882 Biotin-binding site Reactome: R-HSA-196780|Reactome: R-HSA-3371599 ALX04_RS09965 4a73bb77309bbcc5ae0557ee2c073b33 105 Gene3D G3DSA:1.10.10.10 1 93 1.1E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS09965 4a73bb77309bbcc5ae0557ee2c073b33 105 SUPERFAMILY SSF46785 3 101 5.29E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS09965 4a73bb77309bbcc5ae0557ee2c073b33 105 Pfam PF03551 Transcriptional regulator PadR-like family 14 82 1.9E-18 T 28-03-2018 IPR005149 Transcription regulator PadR, N-terminal ALX04_RS15715 78e3b8fa1bc275d14e77126e023725f8 113 Pfam PF15738 Bacterial toxin of type II toxin-antitoxin system, YafQ 11 99 1.5E-19 T 28-03-2018 IPR004386 Toxin-antitoxin system, YafQ-like toxin ALX04_RS15715 78e3b8fa1bc275d14e77126e023725f8 113 SUPERFAMILY SSF143011 10 99 8.5E-10 T 28-03-2018 IPR035095 Toxin RelE-like domain ALX04_RS15715 78e3b8fa1bc275d14e77126e023725f8 113 TIGRFAM TIGR02385 RelE_StbE: addiction module toxin, RelE/StbE family 9 99 1.2E-8 T 28-03-2018 IPR007712 Toxin-antitoxin system, RelE/ParE toxin family ALX04_RS15715 78e3b8fa1bc275d14e77126e023725f8 113 Gene3D G3DSA:3.30.2310.20 7 104 1.9E-13 T 28-03-2018 ALX04_RS09245 2255d9efe6ab246e6235ca71e95da266 204 SMART SM00257 31 74 1.7E-11 T 28-03-2018 IPR018392 LysM domain ALX04_RS09245 2255d9efe6ab246e6235ca71e95da266 204 Gene3D G3DSA:1.10.530.10 77 200 8.8E-12 T 28-03-2018 ALX04_RS09245 2255d9efe6ab246e6235ca71e95da266 204 Pfam PF01476 LysM domain 32 73 3.0E-12 T 28-03-2018 IPR018392 LysM domain ALX04_RS09245 2255d9efe6ab246e6235ca71e95da266 204 Gene3D G3DSA:3.10.350.10 25 76 3.5E-13 T 28-03-2018 ALX04_RS09245 2255d9efe6ab246e6235ca71e95da266 204 SUPERFAMILY SSF53955 133 203 2.28E-7 T 28-03-2018 IPR023346 Lysozyme-like domain ALX04_RS09245 2255d9efe6ab246e6235ca71e95da266 204 SUPERFAMILY SSF54106 31 73 5.23E-11 T 28-03-2018 IPR018392 LysM domain ALX04_RS09245 2255d9efe6ab246e6235ca71e95da266 204 Pfam PF01464 Transglycosylase SLT domain 137 186 8.0E-5 T 28-03-2018 IPR008258 Transglycosylase SLT domain 1 ALX04_RS05255 1949474e10405c5c2a293bdf6bfe974f 161 PIRSF PIRSF006019 1 153 1.2E-55 T 28-03-2018 IPR016473 Deoxycytidylate deaminase GO:0004132|GO:0006220|GO:0008270 KEGG: 00240+3.5.4.12|MetaCyc: PWY-7210|Reactome: R-HSA-499943 ALX04_RS05255 1949474e10405c5c2a293bdf6bfe974f 161 SUPERFAMILY SSF53927 9 135 2.68E-37 T 28-03-2018 IPR016193 Cytidine deaminase-like GO:0003824 ALX04_RS05255 1949474e10405c5c2a293bdf6bfe974f 161 TIGRFAM TIGR02571 ComEB: ComE operon protein 2 4 153 1.5E-90 T 28-03-2018 IPR013404 Competence operon E, ComEB ALX04_RS05255 1949474e10405c5c2a293bdf6bfe974f 161 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 8 118 2.0E-27 T 28-03-2018 IPR002125 Cytidine and deoxycytidylate deaminase domain ALX04_RS05255 1949474e10405c5c2a293bdf6bfe974f 161 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 72 107 - T 28-03-2018 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 ALX04_RS05255 1949474e10405c5c2a293bdf6bfe974f 161 Gene3D G3DSA:3.40.140.10 5 151 1.0E-37 T 28-03-2018 ALX04_RS15780 3127e81b6198753ca4114af0e51a8fdc 197 Gene3D G3DSA:3.20.140.10 1 104 3.6E-18 T 28-03-2018 ALX04_RS15780 3127e81b6198753ca4114af0e51a8fdc 197 SUPERFAMILY SSF51690 2 193 2.62E-40 T 28-03-2018 IPR002638 Quinolinate phosphoribosyl transferase, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 ALX04_RS11075 fb3c283f794b4b4b6ac92db14fcde46d 294 Pfam PF08501 Shikimate dehydrogenase substrate binding domain 14 96 2.9E-30 T 28-03-2018 IPR013708 Shikimate dehydrogenase substrate binding, N-terminal GO:0004764|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163 ALX04_RS11075 fb3c283f794b4b4b6ac92db14fcde46d 294 Gene3D G3DSA:3.40.50.10860 1 120 6.8E-43 T 28-03-2018 ALX04_RS11075 fb3c283f794b4b4b6ac92db14fcde46d 294 SUPERFAMILY SSF51735 109 288 7.22E-31 T 28-03-2018 IPR016040 NAD(P)-binding domain ALX04_RS11075 fb3c283f794b4b4b6ac92db14fcde46d 294 SUPERFAMILY SSF53223 4 108 1.73E-33 T 28-03-2018 ALX04_RS11075 fb3c283f794b4b4b6ac92db14fcde46d 294 Gene3D G3DSA:3.40.50.720 121 293 1.6E-25 T 28-03-2018 ALX04_RS11075 fb3c283f794b4b4b6ac92db14fcde46d 294 Hamap MF_00222 Shikimate dehydrogenase (NADP(+)) [aroE]. 9 289 31.453 T 28-03-2018 IPR022893 Shikimate dehydrogenase family GO:0004764|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163 ALX04_RS14280 647f92facb3a579d0cdb66a6584de68e 61 Gene3D G3DSA:1.20.5.1030 3 54 3.3E-18 T 28-03-2018 ALX04_RS14280 647f92facb3a579d0cdb66a6584de68e 61 ProSitePatterns PS01067 Protein secE/sec61-gamma signature. 6 34 - T 28-03-2018 IPR001901 Protein translocase complex, SecE/Sec61-gamma subunit GO:0006605|GO:0006886|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 ALX04_RS14280 647f92facb3a579d0cdb66a6584de68e 61 TIGRFAM TIGR00964 secE_bact: preprotein translocase, SecE subunit 3 57 3.6E-17 T 28-03-2018 IPR005807 SecE subunit of protein translocation complex GO:0009306|GO:0015450|GO:0016021 ALX04_RS14280 647f92facb3a579d0cdb66a6584de68e 61 Hamap MF_00422 Protein translocase subunit SecE [secE]. 1 57 11.124 T 28-03-2018 IPR022943 Preprotein translocase subunit SecE Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 ALX04_RS14280 647f92facb3a579d0cdb66a6584de68e 61 Pfam PF00584 SecE/Sec61-gamma subunits of protein translocation complex 4 57 4.5E-17 T 28-03-2018 IPR001901 Protein translocase complex, SecE/Sec61-gamma subunit GO:0006605|GO:0006886|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 ALX04_RS07320 5a46410db1dbc7a788ac00b24ea1d349 278 Pfam PF02811 PHP domain 4 186 6.1E-13 T 28-03-2018 IPR004013 PHP domain GO:0003824 ALX04_RS07320 5a46410db1dbc7a788ac00b24ea1d349 278 TIGRFAM TIGR01856 hisJ_fam: histidinol phosphate phosphatase, HisJ family 3 273 8.8E-66 T 28-03-2018 IPR010140 Histidinol phosphate phosphatase, HisJ GO:0000105|GO:0004401 KEGG: 00340+3.1.3.15 ALX04_RS07320 5a46410db1dbc7a788ac00b24ea1d349 278 Pfam PF13263 PHP-associated 241 273 6.9E-7 T 28-03-2018 ALX04_RS07320 5a46410db1dbc7a788ac00b24ea1d349 278 SUPERFAMILY SSF89550 1 276 2.55E-34 T 28-03-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 ALX04_RS07320 5a46410db1dbc7a788ac00b24ea1d349 278 Gene3D G3DSA:3.20.20.140 3 278 1.8E-31 T 28-03-2018 ALX04_RS05885 e14c7dd32c7bdbd77a147656d7f8baa5 118 Gene3D G3DSA:3.30.700.10 19 111 5.0E-13 T 28-03-2018 ALX04_RS05885 e14c7dd32c7bdbd77a147656d7f8baa5 118 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 17 37 - T 28-03-2018 IPR012902 Prokaryotic N-terminal methylation site ALX04_RS05885 e14c7dd32c7bdbd77a147656d7f8baa5 118 SUPERFAMILY SSF54523 19 94 1.8E-15 T 28-03-2018 ALX04_RS05885 e14c7dd32c7bdbd77a147656d7f8baa5 118 PIRSF PIRSF029928 5 116 2.1E-37 T 28-03-2018 IPR016940 ComG operon protein C GO:0030420 ALX04_RS05885 e14c7dd32c7bdbd77a147656d7f8baa5 118 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 16 39 2.1E-9 T 28-03-2018 IPR012902 Prokaryotic N-terminal methylation site ALX04_RS05885 e14c7dd32c7bdbd77a147656d7f8baa5 118 Pfam PF07963 Prokaryotic N-terminal methylation motif 16 38 1.8E-9 T 28-03-2018 IPR012902 Prokaryotic N-terminal methylation site ALX04_RS09915 27d7750f150233104bdb6308bc93f17c 427 Pfam PF07662 Na+ dependent nucleoside transporter C-terminus 194 425 1.4E-53 T 28-03-2018 IPR011657 Concentrative nucleoside transporter C-terminal domain Reactome: R-HSA-83936 ALX04_RS09915 27d7750f150233104bdb6308bc93f17c 427 Pfam PF01773 Na+ dependent nucleoside transporter N-terminus 10 79 5.3E-19 T 28-03-2018 IPR002668 Concentrative nucleoside transporter N-terminal domain Reactome: R-HSA-83936 ALX04_RS01410 6d73464ac38118247c9c9f990dac4b55 88 TIGRFAM TIGR01003 PTS_HPr_family: phosphocarrier, HPr family 1 81 1.6E-31 T 28-03-2018 IPR000032 Phosphocarrier protein HPr-like ALX04_RS01410 6d73464ac38118247c9c9f990dac4b55 88 ProSitePatterns PS00589 PTS HPR domain serine phosphorylation site signature. 39 54 - T 28-03-2018 IPR002114 Phosphotransferase system, HPr serine phosphorylation site ALX04_RS01410 6d73464ac38118247c9c9f990dac4b55 88 PRINTS PR00107 Phosphocarrier protein signature 53 70 1.8E-24 T 28-03-2018 IPR000032 Phosphocarrier protein HPr-like ALX04_RS01410 6d73464ac38118247c9c9f990dac4b55 88 PRINTS PR00107 Phosphocarrier protein signature 13 29 1.8E-24 T 28-03-2018 IPR000032 Phosphocarrier protein HPr-like ALX04_RS01410 6d73464ac38118247c9c9f990dac4b55 88 PRINTS PR00107 Phosphocarrier protein signature 38 53 1.8E-24 T 28-03-2018 IPR000032 Phosphocarrier protein HPr-like ALX04_RS01410 6d73464ac38118247c9c9f990dac4b55 88 SUPERFAMILY SSF55594 1 83 2.22E-27 T 28-03-2018 IPR000032 Phosphocarrier protein HPr-like ALX04_RS01410 6d73464ac38118247c9c9f990dac4b55 88 Pfam PF00381 PTS HPr component phosphorylation site 3 82 1.5E-28 T 28-03-2018 IPR000032 Phosphocarrier protein HPr-like ALX04_RS01410 6d73464ac38118247c9c9f990dac4b55 88 Gene3D G3DSA:3.30.1340.10 1 88 2.6E-30 T 28-03-2018 IPR000032 Phosphocarrier protein HPr-like ALX04_RS01410 6d73464ac38118247c9c9f990dac4b55 88 ProSitePatterns PS00369 PTS HPR domain histidine phosphorylation site signature. 13 20 - T 28-03-2018 IPR001020 Phosphotransferase system, HPr histidine phosphorylation site ALX04_RS14440 c0f4b8cca373e1340b04067e3244f8f2 256 Gene3D G3DSA:3.40.50.300 1 255 1.2E-62 T 28-03-2018 ALX04_RS14440 c0f4b8cca373e1340b04067e3244f8f2 256 Pfam PF00005 ABC transporter 18 174 4.8E-37 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 ALX04_RS14440 c0f4b8cca373e1340b04067e3244f8f2 256 SMART SM00382 27 223 1.0E-12 T 28-03-2018 IPR003593 AAA+ ATPase domain ALX04_RS14440 c0f4b8cca373e1340b04067e3244f8f2 256 SUPERFAMILY SSF52540 1 236 2.54E-61 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase ALX04_RS14440 c0f4b8cca373e1340b04067e3244f8f2 256 ProSitePatterns PS00211 ABC transporters family signature. 146 160 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 ALX04_RS14440 c0f4b8cca373e1340b04067e3244f8f2 256 TIGRFAM TIGR02315 ABC_phnC: phosphonate ABC transporter, ATP-binding protein 1 243 3.2E-110 T 28-03-2018 IPR012693 ABC transporter, phosphonate import, PhnC GO:0005524|GO:0015416|GO:0015716|GO:0016020 ALX04_RS14485 0162f549dec761e322b1a7958993286b 214 Pfam PF02517 CAAX protease self-immunity 118 202 1.2E-17 T 28-03-2018 IPR003675 CAAX amino terminal protease GO:0016020 Reactome: R-HSA-5689880 ALX04_RS06440 fb5444f953f99b194cfec7ae090ff1c8 237 Hamap MF_01393 ATP synthase subunit a [atpB]. 8 236 12.927 T 28-03-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 ALX04_RS06440 fb5444f953f99b194cfec7ae090ff1c8 237 TIGRFAM TIGR01131 ATP_synt_6_or_A: ATP synthase F0, A subunit 19 232 8.0E-44 T 28-03-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 ALX04_RS06440 fb5444f953f99b194cfec7ae090ff1c8 237 Pfam PF00119 ATP synthase A chain 22 230 1.1E-53 T 28-03-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 ALX04_RS06440 fb5444f953f99b194cfec7ae090ff1c8 237 SUPERFAMILY SSF81336 70 230 6.67E-37 T 28-03-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 ALX04_RS06440 fb5444f953f99b194cfec7ae090ff1c8 237 ProSitePatterns PS00449 ATP synthase a subunit signature. 165 174 - T 28-03-2018 IPR023011 ATP synthase, F0 complex, subunit A, active site Reactome: R-HSA-163210|Reactome: R-HSA-8949613 ALX04_RS06440 fb5444f953f99b194cfec7ae090ff1c8 237 PRINTS PR00123 ATP synthase A subunit signature 162 184 2.5E-16 T 28-03-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 ALX04_RS06440 fb5444f953f99b194cfec7ae090ff1c8 237 PRINTS PR00123 ATP synthase A subunit signature 216 231 2.5E-16 T 28-03-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 ALX04_RS06440 fb5444f953f99b194cfec7ae090ff1c8 237 PRINTS PR00123 ATP synthase A subunit signature 78 94 2.5E-16 T 28-03-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 ALX04_RS06440 fb5444f953f99b194cfec7ae090ff1c8 237 Gene3D G3DSA:1.20.120.220 69 236 2.1E-39 T 28-03-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 ALX04_RS00545 cc69b7d640989291bc6b78d4ded22557 370 Gene3D G3DSA:3.10.520.10 27 353 4.7E-46 T 28-03-2018 ALX04_RS00545 cc69b7d640989291bc6b78d4ded22557 370 PIRSF PIRSF006268 20 357 1.1E-106 T 28-03-2018 IPR024932 Flavin transferase ApbE GO:0017013 ALX04_RS00545 cc69b7d640989291bc6b78d4ded22557 370 SUPERFAMILY SSF143631 48 353 2.2E-85 T 28-03-2018 IPR003374 ApbE-like domain ALX04_RS00545 cc69b7d640989291bc6b78d4ded22557 370 Pfam PF02424 ApbE family 53 336 1.1E-76 T 28-03-2018 IPR024932 Flavin transferase ApbE GO:0017013 ALX04_RS12545 ee613ff4d7741dd55249a6bf2cb85e0d 501 SUPERFAMILY SSF56425 278 432 2.88E-24 T 28-03-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 ALX04_RS12545 ee613ff4d7741dd55249a6bf2cb85e0d 501 Pfam PF00890 FAD binding domain 9 464 4.8E-48 T 28-03-2018 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 ALX04_RS12545 ee613ff4d7741dd55249a6bf2cb85e0d 501 Gene3D G3DSA:3.90.700.10 261 430 3.3E-30 T 28-03-2018 ALX04_RS12545 ee613ff4d7741dd55249a6bf2cb85e0d 501 Gene3D G3DSA:3.50.50.60 8 257 1.8E-23 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ALX04_RS12545 ee613ff4d7741dd55249a6bf2cb85e0d 501 SUPERFAMILY SSF51905 276 320 3.39E-37 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ALX04_RS12545 ee613ff4d7741dd55249a6bf2cb85e0d 501 SUPERFAMILY SSF51905 2 208 3.39E-37 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ALX04_RS12545 ee613ff4d7741dd55249a6bf2cb85e0d 501 SUPERFAMILY SSF51905 431 493 3.39E-37 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ALX04_RS10270 608de9aea30d4ed91181cc76481ceb7a 212 Pfam PF03006 Haemolysin-III related 8 204 3.7E-41 T 28-03-2018 IPR004254 AdipoR/Haemolysin-III-related GO:0016021 ALX04_RS10270 608de9aea30d4ed91181cc76481ceb7a 212 TIGRFAM TIGR01065 hlyIII: channel protein, hemolysin III family 12 212 3.0E-56 T 28-03-2018 IPR005744 Hly-III GO:0016021|GO:0019835 ALX04_RS00670 089c960aa9b98e3a7b5cdc47a760561f 472 Pfam PF00939 Sodium:sulfate symporter transmembrane region 9 472 6.1E-139 T 28-03-2018 IPR001898 Solute carrier family 13 GO:0005215|GO:0006814|GO:0016020|GO:0055085 Reactome: R-HSA-433137 ALX04_RS00670 089c960aa9b98e3a7b5cdc47a760561f 472 PIRSF PIRSF002457 1 472 3.8E-139 T 28-03-2018 IPR030676 Citrate carrier CitT-related ALX04_RS00670 089c960aa9b98e3a7b5cdc47a760561f 472 TIGRFAM TIGR00785 dass: transporter, divalent anion:Na+ symporter (DASS) family 29 465 1.4E-123 T 28-03-2018 IPR001898 Solute carrier family 13 GO:0005215|GO:0006814|GO:0016020|GO:0055085 Reactome: R-HSA-433137 ALX04_RS12135 db4b226bd00d586a79d91d51880211f4 151 Pfam PF11457 Protein of unknown function (DUF3021) 7 146 2.6E-29 T 28-03-2018 IPR021560 Protein of unknown function DUF3021 ALX04_RS13145 db8a47e18677983b5bc92a14e3a3cefc 156 SUPERFAMILY SSF46785 4 142 3.79E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS13145 db8a47e18677983b5bc92a14e3a3cefc 156 Pfam PF02082 Transcriptional regulator 4 78 1.8E-16 T 28-03-2018 IPR000944 Transcription regulator Rrf2-type ALX04_RS13145 db8a47e18677983b5bc92a14e3a3cefc 156 Gene3D G3DSA:1.10.10.10 1 156 7.1E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS06790 270885980302a399476ebb9cf341cf45 101 Pfam PF05595 Domain of unknown function (DUF771) 18 96 2.1E-6 T 28-03-2018 IPR008489 Protein of unknown function DUF771 ALX04_RS00075 faed8e690eea632e89c4307088aa9f67 71 Gene3D G3DSA:1.10.10.10 2 70 3.4E-14 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS00075 faed8e690eea632e89c4307088aa9f67 71 Pfam PF13518 Helix-turn-helix domain 17 69 9.0E-18 T 28-03-2018 ALX04_RS00075 faed8e690eea632e89c4307088aa9f67 71 SUPERFAMILY SSF48295 5 69 4.24E-20 T 28-03-2018 IPR010921 Trp repressor/replication initiator GO:0043565 ALX04_RS10195 f7b3c31c753cad37d1dabb54cc161874 325 Gene3D G3DSA:3.20.20.70 4 324 1.8E-64 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 ALX04_RS10195 f7b3c31c753cad37d1dabb54cc161874 325 Hamap MF_01511 GMP reductase [guaC]. 3 325 62.456 T 28-03-2018 IPR005994 Guanosine monophosphate reductase, type2 GO:0003920|GO:0006163|GO:1902560 KEGG: 00230+1.7.1.7 ALX04_RS10195 f7b3c31c753cad37d1dabb54cc161874 325 Pfam PF00478 IMP dehydrogenase / GMP reductase domain 7 311 4.1E-65 T 28-03-2018 IPR001093 IMP dehydrogenase/GMP reductase GO:0003824|GO:0055114 ALX04_RS10195 f7b3c31c753cad37d1dabb54cc161874 325 ProSitePatterns PS00487 IMP dehydrogenase / GMP reductase signature. 166 178 - T 28-03-2018 IPR015875 IMP dehydrogenase / GMP reductase, conserved site GO:0016491|GO:0055114 ALX04_RS10195 f7b3c31c753cad37d1dabb54cc161874 325 TIGRFAM TIGR01306 GMP_reduct_2: guanosine monophosphate reductase 5 325 2.6E-181 T 28-03-2018 IPR005994 Guanosine monophosphate reductase, type2 GO:0003920|GO:0006163|GO:1902560 KEGG: 00230+1.7.1.7 ALX04_RS10195 f7b3c31c753cad37d1dabb54cc161874 325 PIRSF PIRSF036500 1 325 2.5E-188 T 28-03-2018 IPR005994 Guanosine monophosphate reductase, type2 GO:0003920|GO:0006163|GO:1902560 KEGG: 00230+1.7.1.7 ALX04_RS10195 f7b3c31c753cad37d1dabb54cc161874 325 SMART SM01240 4 324 7.0E-106 T 28-03-2018 ALX04_RS10195 f7b3c31c753cad37d1dabb54cc161874 325 SUPERFAMILY SSF51412 4 316 4.32E-88 T 28-03-2018 ALX04_RS09525 cc1aceca4c72486f1e043fea533feb87 401 Gene3D G3DSA:1.20.1250.20 6 196 6.8E-28 T 28-03-2018 ALX04_RS09525 cc1aceca4c72486f1e043fea533feb87 401 Gene3D G3DSA:1.20.1250.20 200 398 1.2E-21 T 28-03-2018 ALX04_RS09525 cc1aceca4c72486f1e043fea533feb87 401 Pfam PF07690 Major Facilitator Superfamily 14 325 3.2E-38 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 ALX04_RS09525 cc1aceca4c72486f1e043fea533feb87 401 SUPERFAMILY SSF103473 8 390 5.75E-60 T 28-03-2018 IPR020846 Major facilitator superfamily domain ALX04_RS14545 5a4ef53161e08dd43c7bef815a27e3a4 391 SUPERFAMILY SSF50156 284 369 2.63E-12 T 28-03-2018 IPR001478 PDZ domain GO:0005515 ALX04_RS14545 5a4ef53161e08dd43c7bef815a27e3a4 391 Gene3D G3DSA:2.30.42.10 283 372 1.8E-10 T 28-03-2018 ALX04_RS10575 19f67555fe86ad2c73d7a308f26ad819 328 Pfam PF02275 Linear amide C-N hydrolases, choloylglycine hydrolase family 2 305 2.1E-80 T 28-03-2018 IPR029132 Choloylglycine hydrolase/NAAA C-terminal ALX04_RS10575 19f67555fe86ad2c73d7a308f26ad819 328 Gene3D G3DSA:3.60.60.10 2 328 7.6E-83 T 28-03-2018 ALX04_RS10575 19f67555fe86ad2c73d7a308f26ad819 328 SUPERFAMILY SSF56235 2 326 1.39E-101 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal ALX04_RS13945 355b7c2fdd0f56c20f7f1b06e2ceaa0a 88 SUPERFAMILY SSF46955 36 82 3.66E-5 T 28-03-2018 IPR009061 Putative DNA-binding domain ALX04_RS13945 355b7c2fdd0f56c20f7f1b06e2ceaa0a 88 Gene3D G3DSA:1.10.10.10 34 87 3.8E-6 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS01140 021c6eec0388f1eeaffa0bc82bfbd53b 386 SUPERFAMILY SSF53756 117 327 3.04E-9 T 28-03-2018 ALX04_RS01140 021c6eec0388f1eeaffa0bc82bfbd53b 386 Pfam PF04464 CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase 19 355 1.2E-58 T 28-03-2018 IPR007554 CDP-glycerol glycerophosphotransferase GO:0016020|GO:0047355 ALX04_RS03985 5bc131abd166f89ffe1a42c88d4f3a88 152 Pfam PF04284 Protein of unknown function (DUF441) 5 144 6.1E-49 T 28-03-2018 IPR007382 Uncharacterised protein family UPF0756, transmembrame ALX04_RS03985 5bc131abd166f89ffe1a42c88d4f3a88 152 Hamap MF_01874 UPF0756 membrane protein YeaL [yeaL]. 1 147 19.017 T 28-03-2018 IPR007382 Uncharacterised protein family UPF0756, transmembrame ALX04_RS03985 5bc131abd166f89ffe1a42c88d4f3a88 152 ProDom PD021096 MEMBRANE YEAL PRECURSOR SIGNAL PROTEIN TRANSMEMBRANE YTWI HI1074 INTEGRAL SPANNING 5 127 3.0E-61 T 28-03-2018 IPR007382 Uncharacterised protein family UPF0756, transmembrame ALX04_RS14120 d3bfe132de12f89a15e065fdf907714a 324 TIGRFAM TIGR00824 EIIA-man: PTS system, mannose/fructose/sorbose family, IIA component 1 110 1.8E-31 T 28-03-2018 IPR013789 Phosphotransferase system, mannose family IIA component GO:0005737|GO:0008643|GO:0016773 ALX04_RS14120 d3bfe132de12f89a15e065fdf907714a 324 SUPERFAMILY SSF53062 1 128 5.62E-38 T 28-03-2018 IPR004701 Phosphotransferase system, mannose-type IIA component GO:0009401|GO:0016021 ALX04_RS14120 d3bfe132de12f89a15e065fdf907714a 324 Gene3D G3DSA:3.40.35.10 157 314 1.3E-52 T 28-03-2018 IPR004720 Phosphotransferase system, sorbose subfamily IIB component GO:0005737|GO:0008982|GO:0009401 ALX04_RS14120 d3bfe132de12f89a15e065fdf907714a 324 Gene3D G3DSA:3.40.50.510 1 142 1.6E-39 T 28-03-2018 IPR004701 Phosphotransferase system, mannose-type IIA component GO:0009401|GO:0016021 ALX04_RS14120 d3bfe132de12f89a15e065fdf907714a 324 Pfam PF03830 PTS system sorbose subfamily IIB component 160 305 1.1E-48 T 28-03-2018 IPR004720 Phosphotransferase system, sorbose subfamily IIB component GO:0005737|GO:0008982|GO:0009401 ALX04_RS14120 d3bfe132de12f89a15e065fdf907714a 324 Pfam PF03610 PTS system fructose IIA component 4 117 2.0E-34 T 28-03-2018 IPR004701 Phosphotransferase system, mannose-type IIA component GO:0009401|GO:0016021 ALX04_RS14120 d3bfe132de12f89a15e065fdf907714a 324 SUPERFAMILY SSF52728 159 316 1.29E-50 T 28-03-2018 IPR004720 Phosphotransferase system, sorbose subfamily IIB component GO:0005737|GO:0008982|GO:0009401 ALX04_RS07520 9325e0b3c109313b295547d1b0087c91 138 SUPERFAMILY SSF47413 2 78 2.82E-10 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 ALX04_RS07520 9325e0b3c109313b295547d1b0087c91 138 SMART SM00530 5 71 4.5E-8 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 ALX04_RS07520 9325e0b3c109313b295547d1b0087c91 138 Gene3D G3DSA:1.10.3100.10 1 121 3.6E-17 T 28-03-2018 IPR027910 YdiL-like domain ALX04_RS07520 9325e0b3c109313b295547d1b0087c91 138 Pfam PF01381 Helix-turn-helix 6 71 5.7E-8 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 ALX04_RS03455 c80de1d710d09db5fb3308dbfcacf0b7 447 Pfam PF01183 Glycosyl hydrolases family 25 32 197 1.2E-21 T 28-03-2018 IPR002053 Glycoside hydrolase, family 25 GO:0003796|GO:0009253|GO:0016998 ALX04_RS03455 c80de1d710d09db5fb3308dbfcacf0b7 447 Gene3D G3DSA:3.20.20.80 24 217 8.2E-32 T 28-03-2018 ALX04_RS03455 c80de1d710d09db5fb3308dbfcacf0b7 447 SUPERFAMILY SSF51445 31 225 2.11E-35 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily ALX04_RS11770 5a6b9d6bb4a92d1ce4221e148be4f92c 216 Pfam PF00881 Nitroreductase family 7 191 1.6E-28 T 28-03-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 ALX04_RS11770 5a6b9d6bb4a92d1ce4221e148be4f92c 216 Gene3D G3DSA:3.40.109.10 1 216 6.5E-39 T 28-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 ALX04_RS11770 5a6b9d6bb4a92d1ce4221e148be4f92c 216 SUPERFAMILY SSF55469 1 62 1.96E-38 T 28-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 ALX04_RS11770 5a6b9d6bb4a92d1ce4221e148be4f92c 216 SUPERFAMILY SSF55469 112 214 1.96E-38 T 28-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 ALX04_RS02490 c376f59160c4e5e4fccabc7879d27321 192 Pfam PF13630 SdpI/YhfL protein family 118 183 1.6E-15 T 28-03-2018 IPR025962 SdpI/YhfL protein family ALX04_RS07065 7458e3f319988d3428552f97a0f9a6c8 664 SMART SM00382 32 218 2.1E-12 T 28-03-2018 IPR003593 AAA+ ATPase domain ALX04_RS07065 7458e3f319988d3428552f97a0f9a6c8 664 ProSitePatterns PS00211 ABC transporters family signature. 144 158 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 ALX04_RS07065 7458e3f319988d3428552f97a0f9a6c8 664 Pfam PF02687 FtsX-like permease family 565 657 3.1E-11 T 28-03-2018 IPR003838 ABC transporter permease protein domain GO:0016020 ALX04_RS07065 7458e3f319988d3428552f97a0f9a6c8 664 Pfam PF12704 MacB-like periplasmic core domain 264 504 8.0E-13 T 28-03-2018 IPR025857 MacB-like periplasmic core domain ALX04_RS07065 7458e3f319988d3428552f97a0f9a6c8 664 Pfam PF00005 ABC transporter 23 171 9.7E-33 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 ALX04_RS07065 7458e3f319988d3428552f97a0f9a6c8 664 SUPERFAMILY SSF52540 4 223 4.6E-68 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase ALX04_RS07065 7458e3f319988d3428552f97a0f9a6c8 664 Gene3D G3DSA:3.40.50.300 1 381 1.2E-64 T 28-03-2018 ALX04_RS03395 f0e3d7bd7a22441164adb6f234cea305 207 Hamap MF_00130 Holliday junction resolvase RecU [recU]. 1 207 101.029 T 28-03-2018 IPR004612 Holliday junction resolvase RecU GO:0005737|GO:0006281|GO:0006310 ALX04_RS03395 f0e3d7bd7a22441164adb6f234cea305 207 SUPERFAMILY SSF52980 34 200 6.43E-68 T 28-03-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 ALX04_RS03395 f0e3d7bd7a22441164adb6f234cea305 207 PIRSF PIRSF037785 23 207 4.8E-82 T 28-03-2018 IPR004612 Holliday junction resolvase RecU GO:0005737|GO:0006281|GO:0006310 ALX04_RS03395 f0e3d7bd7a22441164adb6f234cea305 207 TIGRFAM TIGR00648 recU: recombination protein U 31 198 1.1E-71 T 28-03-2018 IPR004612 Holliday junction resolvase RecU GO:0005737|GO:0006281|GO:0006310 ALX04_RS03395 f0e3d7bd7a22441164adb6f234cea305 207 Gene3D G3DSA:3.40.1350.10 33 199 2.5E-62 T 28-03-2018 ALX04_RS03395 f0e3d7bd7a22441164adb6f234cea305 207 Pfam PF03838 Recombination protein U 32 197 2.5E-67 T 28-03-2018 IPR004612 Holliday junction resolvase RecU GO:0005737|GO:0006281|GO:0006310 ALX04_RS06270 5dcbe324aead0b8b0f2f1c65ced89f50 138 Pfam PF03610 PTS system fructose IIA component 4 101 2.7E-13 T 28-03-2018 IPR004701 Phosphotransferase system, mannose-type IIA component GO:0009401|GO:0016021 ALX04_RS06270 5dcbe324aead0b8b0f2f1c65ced89f50 138 SUPERFAMILY SSF53062 1 128 1.57E-25 T 28-03-2018 IPR004701 Phosphotransferase system, mannose-type IIA component GO:0009401|GO:0016021 ALX04_RS06270 5dcbe324aead0b8b0f2f1c65ced89f50 138 Gene3D G3DSA:3.40.50.510 1 138 3.4E-24 T 28-03-2018 IPR004701 Phosphotransferase system, mannose-type IIA component GO:0009401|GO:0016021 ALX04_RS07430 6d00ba57f8d0fcc7b0f76006712a4e1f 318 Pfam PF01156 Inosine-uridine preferring nucleoside hydrolase 4 305 3.6E-86 T 28-03-2018 IPR001910 Inosine/uridine-preferring nucleoside hydrolase domain ALX04_RS07430 6d00ba57f8d0fcc7b0f76006712a4e1f 318 Gene3D G3DSA:3.90.245.10 1 315 8.0E-99 T 28-03-2018 IPR001910 Inosine/uridine-preferring nucleoside hydrolase domain ALX04_RS07430 6d00ba57f8d0fcc7b0f76006712a4e1f 318 SUPERFAMILY SSF53590 3 312 8.63E-91 T 28-03-2018 IPR001910 Inosine/uridine-preferring nucleoside hydrolase domain ALX04_RS12815 ad1f22c545e725a03d099b08b76e5a12 243 Pfam PF01418 Helix-turn-helix domain, rpiR family 7 72 2.8E-14 T 28-03-2018 IPR000281 Helix-turn-helix protein RpiR GO:0003700|GO:0006355 ALX04_RS12815 ad1f22c545e725a03d099b08b76e5a12 243 Gene3D G3DSA:1.10.10.10 4 103 1.2E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS12815 ad1f22c545e725a03d099b08b76e5a12 243 SUPERFAMILY SSF46689 5 73 1.51E-18 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 ALX04_RS12815 ad1f22c545e725a03d099b08b76e5a12 243 Gene3D G3DSA:3.40.50.10490 104 238 2.8E-22 T 28-03-2018 ALX04_RS12815 ad1f22c545e725a03d099b08b76e5a12 243 Pfam PF01380 SIS domain 109 215 1.9E-12 T 28-03-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 ALX04_RS12815 ad1f22c545e725a03d099b08b76e5a12 243 SUPERFAMILY SSF53697 88 232 6.55E-29 T 28-03-2018 ALX04_RS14505 91a91ffa05767f8cd686639fd2fc0992 365 Pfam PF00953 Glycosyl transferase family 4 79 234 9.7E-39 T 28-03-2018 IPR000715 Glycosyl transferase, family 4 GO:0008963|GO:0016021 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193 ALX04_RS14505 91a91ffa05767f8cd686639fd2fc0992 365 ProSitePatterns PS01348 MraY family signature 2. 153 164 - T 28-03-2018 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 ALX04_RS12090 10d9c939b3b812f8cc5ad50f665f71d3 301 TIGRFAM TIGR00287 cas1: CRISPR-associated endonuclease Cas1 6 229 8.3E-26 T 28-03-2018 IPR002729 CRISPR-associated protein Cas1 GO:0003676|GO:0004519|GO:0043571|GO:0046872|GO:0051607 ALX04_RS12090 10d9c939b3b812f8cc5ad50f665f71d3 301 Pfam PF01867 CRISPR associated protein Cas1 7 228 2.6E-26 T 28-03-2018 IPR002729 CRISPR-associated protein Cas1 GO:0003676|GO:0004519|GO:0043571|GO:0046872|GO:0051607 ALX04_RS12090 10d9c939b3b812f8cc5ad50f665f71d3 301 TIGRFAM TIGR03639 cas1_NMENI: CRISPR-associated endonuclease Cas1, subtype II/NMENI 3 270 3.1E-79 T 28-03-2018 IPR019855 CRISPR-associated protein Cas1, NMENI subtype GO:0004520|GO:0043571|GO:0046872 ALX04_RS12090 10d9c939b3b812f8cc5ad50f665f71d3 301 Hamap MF_01470 CRISPR-associated endonuclease Cas1 [cas1]. 3 290 16.532 T 28-03-2018 IPR002729 CRISPR-associated protein Cas1 GO:0003676|GO:0004519|GO:0043571|GO:0046872|GO:0051607 ALX04_RS05995 3198b6a6363deacb8c71c0c468921b8c 83 Pfam PF05164 Cell division protein ZapA 11 77 2.0E-7 T 28-03-2018 IPR007838 Cell division protein ZapA-like ALX04_RS05995 3198b6a6363deacb8c71c0c468921b8c 83 SUPERFAMILY SSF102829 9 79 7.32E-10 T 28-03-2018 IPR007838 Cell division protein ZapA-like ALX04_RS09055 0ac8a4a579b9f674b2a6a0317bfc43c4 257 Pfam PF00005 ABC transporter 27 182 1.9E-28 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 ALX04_RS09055 0ac8a4a579b9f674b2a6a0317bfc43c4 257 Gene3D G3DSA:3.40.50.300 3 247 7.8E-55 T 28-03-2018 ALX04_RS09055 0ac8a4a579b9f674b2a6a0317bfc43c4 257 SMART SM00382 36 230 6.6E-10 T 28-03-2018 IPR003593 AAA+ ATPase domain ALX04_RS09055 0ac8a4a579b9f674b2a6a0317bfc43c4 257 SUPERFAMILY SSF52540 2 233 2.56E-53 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase ALX04_RS09055 0ac8a4a579b9f674b2a6a0317bfc43c4 257 ProSitePatterns PS00211 ABC transporters family signature. 154 168 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 ALX04_RS15980 7cc627e161d5b6f17c2fefc7fd6c4b77 328 Pfam PF01548 Transposase 11 76 5.4E-12 T 28-03-2018 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 ALX04_RS15980 7cc627e161d5b6f17c2fefc7fd6c4b77 328 Pfam PF02371 Transposase IS116/IS110/IS902 family 188 260 3.7E-23 T 28-03-2018 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 ALX04_RS00900 a9216b18c25b9322f6fd8dabe0afda08 191 Gene3D G3DSA:1.10.357.10 2 179 1.2E-21 T 28-03-2018 ALX04_RS00900 a9216b18c25b9322f6fd8dabe0afda08 191 SUPERFAMILY SSF46689 7 74 1.75E-10 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 ALX04_RS00575 1d45019ebac80a27d57df194879c0624 130 SUPERFAMILY SSF54211 6 130 4.55E-47 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold ALX04_RS00575 1d45019ebac80a27d57df194879c0624 130 Pfam PF00380 Ribosomal protein S9/S16 10 130 1.8E-45 T 28-03-2018 IPR000754 Ribosomal protein S9 GO:0003735|GO:0005840|GO:0006412 ALX04_RS00575 1d45019ebac80a27d57df194879c0624 130 Gene3D G3DSA:3.30.230.10 3 130 1.2E-49 T 28-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup ALX04_RS00575 1d45019ebac80a27d57df194879c0624 130 ProSitePatterns PS00360 Ribosomal protein S9 signature. 69 87 - T 28-03-2018 IPR020574 Ribosomal protein S9, conserved site GO:0003735|GO:0005840|GO:0006412 ALX04_RS00575 1d45019ebac80a27d57df194879c0624 130 Hamap MF_00532_B 30S ribosomal protein S9 [rpsI]. 1 130 33.15 T 28-03-2018 IPR023035 Ribosomal protein S9, bacterial/plastid ALX04_RS10990 f37e87374cfcc7b3cc69de34144d1375 199 SUPERFAMILY SSF140931 61 197 1.96E-23 T 28-03-2018 IPR003812 Fido domain ALX04_RS10990 f37e87374cfcc7b3cc69de34144d1375 199 Gene3D G3DSA:1.10.3290.10 15 199 9.4E-19 T 28-03-2018 IPR003812 Fido domain ALX04_RS10990 f37e87374cfcc7b3cc69de34144d1375 199 Pfam PF02661 Fic/DOC family 62 159 1.9E-12 T 28-03-2018 IPR003812 Fido domain ALX04_RS00450 09bba6c83432644fff145d4c1ec73754 131 ProSitePatterns PS00053 Ribosomal protein S8 signature. 101 118 - T 28-03-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 ALX04_RS00450 09bba6c83432644fff145d4c1ec73754 131 SUPERFAMILY SSF56047 1 131 1.44E-49 T 28-03-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 ALX04_RS00450 09bba6c83432644fff145d4c1ec73754 131 Gene3D G3DSA:3.30.1490.10 75 130 3.3E-23 T 28-03-2018 ALX04_RS00450 09bba6c83432644fff145d4c1ec73754 131 Hamap MF_01302_B 30S ribosomal protein S8 [rpsH]. 1 131 32.532 T 28-03-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 ALX04_RS00450 09bba6c83432644fff145d4c1ec73754 131 Gene3D G3DSA:3.30.1370.30 1 66 3.0E-26 T 28-03-2018 ALX04_RS00450 09bba6c83432644fff145d4c1ec73754 131 Pfam PF00410 Ribosomal protein S8 4 131 2.3E-53 T 28-03-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 ALX04_RS03795 7deb6828130024510e937ff1341f2587 288 SUPERFAMILY SSF102405 78 273 1.35E-33 T 28-03-2018 ALX04_RS03795 7deb6828130024510e937ff1341f2587 288 Gene3D G3DSA:3.40.50.450 108 253 6.4E-37 T 28-03-2018 ALX04_RS03795 7deb6828130024510e937ff1341f2587 288 Pfam PF02481 DNA recombination-mediator protein A 72 274 1.4E-74 T 28-03-2018 IPR003488 DNA recombination-mediator protein A GO:0009294 ALX04_RS03795 7deb6828130024510e937ff1341f2587 288 TIGRFAM TIGR00732 dprA: DNA protecting protein DprA 71 283 1.8E-68 T 28-03-2018 IPR003488 DNA recombination-mediator protein A GO:0009294 ALX04_RS10405 335e864f7a2be6c5a6b48022e3dc7955 306 Gene3D G3DSA:3.20.20.100 1 304 5.8E-71 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain ALX04_RS10405 335e864f7a2be6c5a6b48022e3dc7955 306 SUPERFAMILY SSF51430 2 298 4.32E-74 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain ALX04_RS10405 335e864f7a2be6c5a6b48022e3dc7955 306 PRINTS PR00069 Aldo-keto reductase signature 102 120 4.2E-9 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 ALX04_RS10405 335e864f7a2be6c5a6b48022e3dc7955 306 PRINTS PR00069 Aldo-keto reductase signature 38 62 4.2E-9 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 ALX04_RS10405 335e864f7a2be6c5a6b48022e3dc7955 306 PRINTS PR00069 Aldo-keto reductase signature 133 150 4.2E-9 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 ALX04_RS10405 335e864f7a2be6c5a6b48022e3dc7955 306 Pfam PF00248 Aldo/keto reductase family 17 296 3.0E-50 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain ALX04_RS14740 48bef5afcb80ae4db14b7821d95f8eb2 445 PRINTS PR00045 Sigma-54 factor signature 151 168 2.2E-22 T 28-03-2018 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 ALX04_RS14740 48bef5afcb80ae4db14b7821d95f8eb2 445 PRINTS PR00045 Sigma-54 factor signature 338 350 2.2E-22 T 28-03-2018 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 ALX04_RS14740 48bef5afcb80ae4db14b7821d95f8eb2 445 PRINTS PR00045 Sigma-54 factor signature 414 432 2.2E-22 T 28-03-2018 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 ALX04_RS14740 48bef5afcb80ae4db14b7821d95f8eb2 445 PRINTS PR00045 Sigma-54 factor signature 354 365 2.2E-22 T 28-03-2018 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 ALX04_RS14740 48bef5afcb80ae4db14b7821d95f8eb2 445 ProSitePatterns PS00718 Sigma-54 factors family signature 2. 419 426 - T 28-03-2018 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 ALX04_RS14740 48bef5afcb80ae4db14b7821d95f8eb2 445 PIRSF PIRSF000774 4 441 3.2E-113 T 28-03-2018 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 ALX04_RS14740 48bef5afcb80ae4db14b7821d95f8eb2 445 ProSitePatterns PS00717 Sigma-54 factors family signature 1. 326 345 - T 28-03-2018 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 ALX04_RS14740 48bef5afcb80ae4db14b7821d95f8eb2 445 Pfam PF04963 Sigma-54 factor, core binding domain 82 265 4.3E-40 T 28-03-2018 IPR007046 RNA polymerase sigma factor 54, core-binding GO:0003677|GO:0006352 ALX04_RS14740 48bef5afcb80ae4db14b7821d95f8eb2 445 TIGRFAM TIGR02395 rpoN_sigma: RNA polymerase sigma-54 factor 13 438 1.1E-131 T 28-03-2018 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 ALX04_RS14740 48bef5afcb80ae4db14b7821d95f8eb2 445 Gene3D G3DSA:1.10.10.10 284 376 1.7E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS14740 48bef5afcb80ae4db14b7821d95f8eb2 445 Pfam PF00309 Sigma-54 factor, Activator interacting domain (AID) 8 52 1.9E-15 T 28-03-2018 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 ALX04_RS14740 48bef5afcb80ae4db14b7821d95f8eb2 445 Pfam PF04552 Sigma-54, DNA binding domain 279 439 3.6E-60 T 28-03-2018 IPR007634 RNA polymerase sigma factor 54, DNA-binding ALX04_RS12400 a3a6d757fdfb7ff3434e5f59b8b3bee8 557 Pfam PF11941 Domain of unknown function (DUF3459) 469 536 7.4E-6 T 28-03-2018 IPR022567 Glycosyl hydrolase, C-terminal (DUF3459) ALX04_RS12400 a3a6d757fdfb7ff3434e5f59b8b3bee8 557 SUPERFAMILY SSF51445 4 483 4.64E-154 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily ALX04_RS12400 a3a6d757fdfb7ff3434e5f59b8b3bee8 557 Pfam PF00128 Alpha amylase, catalytic domain 28 381 8.2E-123 T 28-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 ALX04_RS12400 a3a6d757fdfb7ff3434e5f59b8b3bee8 557 SUPERFAMILY SSF51011 486 556 1.63E-14 T 28-03-2018 ALX04_RS12400 a3a6d757fdfb7ff3434e5f59b8b3bee8 557 Gene3D G3DSA:2.60.40.1180 510 556 9.7E-8 T 28-03-2018 ALX04_RS12400 a3a6d757fdfb7ff3434e5f59b8b3bee8 557 SMART SM00642 13 425 8.3E-150 T 28-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 ALX04_RS12400 a3a6d757fdfb7ff3434e5f59b8b3bee8 557 Gene3D G3DSA:3.20.20.80 1 263 2.5E-72 T 28-03-2018 ALX04_RS12400 a3a6d757fdfb7ff3434e5f59b8b3bee8 557 Gene3D G3DSA:3.20.20.80 264 509 2.7E-63 T 28-03-2018 ALX04_RS14305 2fd2dacc09140bdb25c5886994f41160 167 ProDom PD968187 BETA-DEFENSIN ANTIBIOTIC PRECURSOR ANTIMICROBIAL DEFENSIN BETA SIGNAL DEFENSIN BD-32 DEFB-32 31 145 6.0E-9 T 28-03-2018 ALX04_RS14305 2fd2dacc09140bdb25c5886994f41160 167 Pfam PF00466 Ribosomal protein L10 5 102 1.4E-31 T 28-03-2018 IPR001790 Ribosomal protein L10P GO:0005622|GO:0042254 ALX04_RS14305 2fd2dacc09140bdb25c5886994f41160 167 Hamap MF_00362 50S ribosomal protein L10 [rplJ]. 4 162 27.747 T 28-03-2018 IPR022973 Ribosomal protein L10 ALX04_RS14305 2fd2dacc09140bdb25c5886994f41160 167 ProSitePatterns PS01109 Ribosomal protein L10 signature. 9 43 - T 28-03-2018 IPR002363 Ribosomal protein L10, eubacterial, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 ALX04_RS14305 2fd2dacc09140bdb25c5886994f41160 167 SUPERFAMILY SSF160369 5 161 1.44E-54 T 28-03-2018 ALX04_RS04045 acbbfbf46991e50409199cf7ef9e346e 168 SMART SM00347 29 125 4.0E-6 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 ALX04_RS04045 acbbfbf46991e50409199cf7ef9e346e 168 SUPERFAMILY SSF46785 38 140 4.87E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS04045 acbbfbf46991e50409199cf7ef9e346e 168 Pfam PF01047 MarR family 39 93 1.9E-9 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 ALX04_RS04045 acbbfbf46991e50409199cf7ef9e346e 168 Gene3D G3DSA:1.10.10.10 4 152 1.6E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS10900 bb8c6e37a7d0a68303acd7481a708d2f 230 Pfam PF13731 WxL domain surface cell wall-binding 31 229 6.3E-30 T 28-03-2018 IPR027994 WxL domain ALX04_RS12470 54aea14a7dd57ac680d8f4e8f197f6ef 395 Hamap MF_00020 Acetate kinase [ackA]. 1 395 159.418 T 28-03-2018 IPR004372 Acetate/propionate kinase GO:0006082|GO:0016301|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 ALX04_RS12470 54aea14a7dd57ac680d8f4e8f197f6ef 395 ProSitePatterns PS01076 Acetate and butyrate kinases family signature 2. 203 220 - T 28-03-2018 IPR023865 Aliphatic acid kinase, short-chain, conserved site GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 ALX04_RS12470 54aea14a7dd57ac680d8f4e8f197f6ef 395 ProSitePatterns PS01075 Acetate and butyrate kinases family signature 1. 4 15 - T 28-03-2018 IPR023865 Aliphatic acid kinase, short-chain, conserved site GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 ALX04_RS12470 54aea14a7dd57ac680d8f4e8f197f6ef 395 PRINTS PR00471 Acetate kinase family signature 300 313 7.3E-38 T 28-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 ALX04_RS12470 54aea14a7dd57ac680d8f4e8f197f6ef 395 PRINTS PR00471 Acetate kinase family signature 173 186 7.3E-38 T 28-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 ALX04_RS12470 54aea14a7dd57ac680d8f4e8f197f6ef 395 PRINTS PR00471 Acetate kinase family signature 322 338 7.3E-38 T 28-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 ALX04_RS12470 54aea14a7dd57ac680d8f4e8f197f6ef 395 PRINTS PR00471 Acetate kinase family signature 203 224 7.3E-38 T 28-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 ALX04_RS12470 54aea14a7dd57ac680d8f4e8f197f6ef 395 PRINTS PR00471 Acetate kinase family signature 4 15 7.3E-38 T 28-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 ALX04_RS12470 54aea14a7dd57ac680d8f4e8f197f6ef 395 PRINTS PR00471 Acetate kinase family signature 375 387 7.3E-38 T 28-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 ALX04_RS12470 54aea14a7dd57ac680d8f4e8f197f6ef 395 SUPERFAMILY SSF53067 157 393 4.43E-78 T 28-03-2018 ALX04_RS12470 54aea14a7dd57ac680d8f4e8f197f6ef 395 TIGRFAM TIGR00016 ackA: acetate kinase 2 393 7.2E-133 T 28-03-2018 IPR004372 Acetate/propionate kinase GO:0006082|GO:0016301|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 ALX04_RS12470 54aea14a7dd57ac680d8f4e8f197f6ef 395 SUPERFAMILY SSF53067 1 195 4.21E-59 T 28-03-2018 ALX04_RS12470 54aea14a7dd57ac680d8f4e8f197f6ef 395 Gene3D G3DSA:3.30.420.40 196 395 5.6E-71 T 28-03-2018 ALX04_RS12470 54aea14a7dd57ac680d8f4e8f197f6ef 395 PIRSF PIRSF000722 1 395 3.9E-136 T 28-03-2018 IPR004372 Acetate/propionate kinase GO:0006082|GO:0016301|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 ALX04_RS12470 54aea14a7dd57ac680d8f4e8f197f6ef 395 Pfam PF00871 Acetokinase family 3 387 3.3E-129 T 28-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 ALX04_RS12470 54aea14a7dd57ac680d8f4e8f197f6ef 395 Gene3D G3DSA:3.30.420.40 3 195 1.6E-62 T 28-03-2018 ALX04_RS00705 78c974f6488df0c93af9d11905a6c649 332 Gene3D G3DSA:1.10.10.60 4 48 4.3E-8 T 28-03-2018 ALX04_RS00705 78c974f6488df0c93af9d11905a6c649 332 Gene3D G3DSA:3.30.420.10 173 332 2.9E-25 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 ALX04_RS00705 78c974f6488df0c93af9d11905a6c649 332 Pfam PF13936 Helix-turn-helix domain 4 46 3.3E-11 T 28-03-2018 IPR025246 Transposase IS30-like HTH domain ALX04_RS00705 78c974f6488df0c93af9d11905a6c649 332 Pfam PF00665 Integrase core domain 180 285 4.9E-12 T 28-03-2018 IPR001584 Integrase, catalytic core GO:0015074 ALX04_RS00705 78c974f6488df0c93af9d11905a6c649 332 ProSitePatterns PS01043 Transposases, IS30 family, signature. 272 288 - T 28-03-2018 IPR001598 Transposase, IS30, conserved site GO:0003677|GO:0004803|GO:0006313 ALX04_RS00705 78c974f6488df0c93af9d11905a6c649 332 SUPERFAMILY SSF53098 179 331 6.58E-30 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 ALX04_RS12855 6fc1be5f1984a2410edacd4aef1249be 190 Pfam PF14278 Transcriptional regulator C-terminal region 87 160 1.3E-9 T 28-03-2018 ALX04_RS12855 6fc1be5f1984a2410edacd4aef1249be 190 Gene3D G3DSA:1.10.357.10 3 188 8.3E-18 T 28-03-2018 ALX04_RS12855 6fc1be5f1984a2410edacd4aef1249be 190 SUPERFAMILY SSF46689 8 75 3.69E-12 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 ALX04_RS08425 d62be0e80925527082b88acf22ad2e76 336 Pfam PF03601 Conserved hypothetical protein 698 8 314 1.1E-73 T 28-03-2018 IPR018383 Uncharacterised protein family UPF0324, prokaryote GO:0016021 ALX04_RS04360 83b2612b449be519782f0dfeb8d3f7be 138 Pfam PF01219 Prokaryotic diacylglycerol kinase 24 125 2.2E-30 T 28-03-2018 IPR000829 DAGK family GO:0004143|GO:0008654|GO:0016020 KEGG: 00500+2.7.1.10|KEGG: 00561+2.7.1.107|KEGG: 00564+2.7.1.107|KEGG: 04070+2.7.1.107|MetaCyc: PWY-7039|MetaCyc: PWY-7817 ALX04_RS04360 83b2612b449be519782f0dfeb8d3f7be 138 Gene3D G3DSA:1.10.3830.10 14 127 6.1E-35 T 28-03-2018 IPR000829 DAGK family GO:0004143|GO:0008654|GO:0016020 KEGG: 00500+2.7.1.10|KEGG: 00561+2.7.1.107|KEGG: 00564+2.7.1.107|KEGG: 04070+2.7.1.107|MetaCyc: PWY-7039|MetaCyc: PWY-7817 ALX04_RS09220 95e6b0b2eecd38f4f7c9326510d986e6 108 Pfam PF02302 PTS system, Lactose/Cellobiose specific IIB subunit 6 99 4.3E-22 T 28-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 ALX04_RS09220 95e6b0b2eecd38f4f7c9326510d986e6 108 Gene3D G3DSA:3.40.50.2300 5 108 3.5E-36 T 28-03-2018 ALX04_RS09220 95e6b0b2eecd38f4f7c9326510d986e6 108 SUPERFAMILY SSF52794 4 106 1.23E-34 T 28-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 ALX04_RS09380 8e339ef6e1808bc9501c09443918afa4 273 SMART SM00530 6 60 5.2E-10 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 ALX04_RS09380 8e339ef6e1808bc9501c09443918afa4 273 Gene3D G3DSA:1.10.3100.10 1 137 1.7E-12 T 28-03-2018 IPR027910 YdiL-like domain ALX04_RS09380 8e339ef6e1808bc9501c09443918afa4 273 Pfam PF12844 Helix-turn-helix domain 4 58 7.7E-9 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 ALX04_RS09380 8e339ef6e1808bc9501c09443918afa4 273 SUPERFAMILY SSF47413 1 60 2.04E-12 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 ALX04_RS05585 8addde1d85a4e3937533b912a0b4ba29 215 Pfam PF13460 NAD(P)H-binding 7 188 7.9E-15 T 28-03-2018 IPR016040 NAD(P)-binding domain ALX04_RS05585 8addde1d85a4e3937533b912a0b4ba29 215 SUPERFAMILY SSF51735 1 214 1.2E-23 T 28-03-2018 IPR016040 NAD(P)-binding domain ALX04_RS05585 8addde1d85a4e3937533b912a0b4ba29 215 Gene3D G3DSA:3.40.50.720 1 215 2.5E-18 T 28-03-2018 ALX04_RS11115 c147f79fc784f317a78327d6a53b1d34 397 Pfam PF07690 Major Facilitator Superfamily 13 310 5.3E-23 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 ALX04_RS11115 c147f79fc784f317a78327d6a53b1d34 397 Gene3D G3DSA:1.20.1250.20 3 198 6.2E-23 T 28-03-2018 ALX04_RS11115 c147f79fc784f317a78327d6a53b1d34 397 ProSitePatterns PS00216 Sugar transport proteins signature 1. 63 79 - T 28-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 ALX04_RS11115 c147f79fc784f317a78327d6a53b1d34 397 SUPERFAMILY SSF103473 7 395 1.31E-37 T 28-03-2018 IPR020846 Major facilitator superfamily domain ALX04_RS11115 c147f79fc784f317a78327d6a53b1d34 397 Gene3D G3DSA:1.20.1250.20 214 394 9.3E-16 T 28-03-2018 ALX04_RS11735 a06e2065506d9cd4199279a790447122 271 SMART SM00849 20 225 3.3E-10 T 28-03-2018 IPR001279 Metallo-beta-lactamase ALX04_RS11735 a06e2065506d9cd4199279a790447122 271 SUPERFAMILY SSF56281 10 238 5.37E-41 T 28-03-2018 IPR001279 Metallo-beta-lactamase ALX04_RS11735 a06e2065506d9cd4199279a790447122 271 Gene3D G3DSA:3.60.15.10 3 268 1.5E-31 T 28-03-2018 IPR001279 Metallo-beta-lactamase ALX04_RS11735 a06e2065506d9cd4199279a790447122 271 Pfam PF12706 Beta-lactamase superfamily domain 31 225 2.8E-19 T 28-03-2018 IPR001279 Metallo-beta-lactamase ALX04_RS00540 186c7f39603d21114584936a6b703c41 308 Pfam PF04205 FMN-binding domain 200 285 5.1E-6 T 28-03-2018 IPR007329 FMN-binding GO:0010181|GO:0016020 ALX04_RS00540 186c7f39603d21114584936a6b703c41 308 Pfam PF04205 FMN-binding domain 76 165 1.3E-5 T 28-03-2018 IPR007329 FMN-binding GO:0010181|GO:0016020 ALX04_RS00540 186c7f39603d21114584936a6b703c41 308 SMART SM00900 200 291 7.6E-9 T 28-03-2018 IPR007329 FMN-binding GO:0010181|GO:0016020 ALX04_RS00540 186c7f39603d21114584936a6b703c41 308 SMART SM00900 74 169 1.6E-9 T 28-03-2018 IPR007329 FMN-binding GO:0010181|GO:0016020 ALX04_RS06315 011c07f3f0eaf23161804de7dd7a6a62 160 PRINTS PR01438 Universal stress protein signature 5 23 1.4E-17 T 28-03-2018 IPR006015 Universal stress protein A ALX04_RS06315 011c07f3f0eaf23161804de7dd7a6a62 160 PRINTS PR01438 Universal stress protein signature 106 118 1.4E-17 T 28-03-2018 IPR006015 Universal stress protein A ALX04_RS06315 011c07f3f0eaf23161804de7dd7a6a62 160 PRINTS PR01438 Universal stress protein signature 124 146 1.4E-17 T 28-03-2018 IPR006015 Universal stress protein A ALX04_RS06315 011c07f3f0eaf23161804de7dd7a6a62 160 SUPERFAMILY SSF52402 5 151 2.76E-33 T 28-03-2018 ALX04_RS06315 011c07f3f0eaf23161804de7dd7a6a62 160 Pfam PF00582 Universal stress protein family 5 146 1.3E-30 T 28-03-2018 IPR006016 UspA GO:0006950 ALX04_RS06315 011c07f3f0eaf23161804de7dd7a6a62 160 Gene3D G3DSA:3.40.50.620 1 150 2.3E-32 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold ALX04_RS06315 011c07f3f0eaf23161804de7dd7a6a62 160 PIRSF PIRSF006276 1 148 1.3E-17 T 28-03-2018 IPR006015 Universal stress protein A ALX04_RS02220 6da3dbaa1303405ea6bb84dd2ba82e33 261 Gene3D G3DSA:3.90.1200.10 27 251 2.5E-24 T 28-03-2018 ALX04_RS02220 6da3dbaa1303405ea6bb84dd2ba82e33 261 Pfam PF01636 Phosphotransferase enzyme family 40 211 7.9E-18 T 28-03-2018 IPR002575 Aminoglycoside phosphotransferase ALX04_RS02220 6da3dbaa1303405ea6bb84dd2ba82e33 261 SUPERFAMILY SSF56112 9 223 4.88E-28 T 28-03-2018 IPR011009 Protein kinase-like domain ALX04_RS01655 3ade5ea6023dd769de0a399a8364b8f8 556 PIRSF PIRSF038958 20 551 2.4E-80 T 28-03-2018 IPR024923 Peptidoglycan biosynthesis protein, SpoVB-type ALX04_RS01655 3ade5ea6023dd769de0a399a8364b8f8 556 Pfam PF14667 Polysaccharide biosynthesis C-terminal domain 389 536 8.0E-23 T 28-03-2018 IPR029303 Polysaccharide biosynthesis protein, C-terminal domain ALX04_RS01655 3ade5ea6023dd769de0a399a8364b8f8 556 Pfam PF01943 Polysaccharide biosynthesis protein 26 337 3.5E-25 T 28-03-2018 IPR002797 Polysaccharide biosynthesis protein GO:0016020 ALX04_RS07175 baf74b885a56f8b3be19ae50591f4b6e 517 SUPERFAMILY SSF52540 4 235 5.85E-45 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase ALX04_RS07175 baf74b885a56f8b3be19ae50591f4b6e 517 ProSitePatterns PS00211 ABC transporters family signature. 160 174 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 ALX04_RS07175 baf74b885a56f8b3be19ae50591f4b6e 517 Gene3D G3DSA:3.40.50.300 1 269 5.3E-50 T 28-03-2018 ALX04_RS07175 baf74b885a56f8b3be19ae50591f4b6e 517 Gene3D G3DSA:3.40.50.300 284 516 3.4E-34 T 28-03-2018 ALX04_RS07175 baf74b885a56f8b3be19ae50591f4b6e 517 Pfam PF00005 ABC transporter 20 188 4.2E-25 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 ALX04_RS07175 baf74b885a56f8b3be19ae50591f4b6e 517 Pfam PF00005 ABC transporter 336 466 7.8E-17 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 ALX04_RS07175 baf74b885a56f8b3be19ae50591f4b6e 517 SUPERFAMILY SSF52540 322 507 1.44E-32 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase ALX04_RS07175 baf74b885a56f8b3be19ae50591f4b6e 517 SMART SM00382 345 511 1.1E-5 T 28-03-2018 IPR003593 AAA+ ATPase domain ALX04_RS07175 baf74b885a56f8b3be19ae50591f4b6e 517 SMART SM00382 28 249 3.6E-9 T 28-03-2018 IPR003593 AAA+ ATPase domain ALX04_RS07175 baf74b885a56f8b3be19ae50591f4b6e 517 Pfam PF12848 ABC transporter 228 309 2.4E-20 T 28-03-2018 IPR032781 ABC-transporter extension domain ALX04_RS10090 a3b14cfeb6aa00e2a55b3ab58a85819c 183 Pfam PF03358 NADPH-dependent FMN reductase 1 144 4.3E-37 T 28-03-2018 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 ALX04_RS10090 a3b14cfeb6aa00e2a55b3ab58a85819c 183 SUPERFAMILY SSF52218 1 171 1.34E-44 T 28-03-2018 IPR029039 Flavoprotein-like domain ALX04_RS10090 a3b14cfeb6aa00e2a55b3ab58a85819c 183 Gene3D G3DSA:3.40.50.360 1 183 7.9E-37 T 28-03-2018 IPR029039 Flavoprotein-like domain ALX04_RS12485 776fbab75e916bf606e9d37724f49246 127 Pfam PF02537 CrcB-like protein, Camphor Resistance (CrcB) 7 114 2.3E-19 T 28-03-2018 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 ALX04_RS12485 776fbab75e916bf606e9d37724f49246 127 Hamap MF_00454 Putative fluoride ion transporter CrcB [crcB]. 4 119 16.255 T 28-03-2018 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 ALX04_RS04590 9bd77a6298154140fa12f0afb1888c82 101 Gene3D G3DSA:3.30.1330.30 1 100 6.0E-16 T 28-03-2018 IPR029064 50S ribosomal protein L30e-like ALX04_RS04590 9bd77a6298154140fa12f0afb1888c82 101 Pfam PF01248 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family 6 95 2.6E-11 T 28-03-2018 IPR004038 Ribosomal protein L7Ae/L30e/S12e/Gadd45 ALX04_RS04590 9bd77a6298154140fa12f0afb1888c82 101 SUPERFAMILY SSF55315 7 99 7.26E-22 T 28-03-2018 IPR029064 50S ribosomal protein L30e-like ALX04_RS12820 ae85e72b3ed20f80f2d92ebf5c4ca9d4 441 PIRSF PIRSF006351 4 435 2.0E-139 T 28-03-2018 IPR004796 Phosphotransferase system, cellobiose-type IIC component GO:0008982|GO:0009401|GO:0016021 ALX04_RS12820 ae85e72b3ed20f80f2d92ebf5c4ca9d4 441 TIGRFAM TIGR00410 lacE: PTS system, lactose/cellobiose family IIC component 15 427 1.8E-143 T 28-03-2018 IPR004501 Phosphotransferase system, EIIC component, type 3 GO:0008982|GO:0009401|GO:0016021 ALX04_RS12820 ae85e72b3ed20f80f2d92ebf5c4ca9d4 441 Pfam PF02378 Phosphotransferase system, EIIC 32 353 2.7E-61 T 28-03-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 ALX04_RS12820 ae85e72b3ed20f80f2d92ebf5c4ca9d4 441 TIGRFAM TIGR00359 cello_pts_IIC: PTS system, cellobiose-specific IIC component 15 427 1.8E-143 T 28-03-2018 IPR004796 Phosphotransferase system, cellobiose-type IIC component GO:0008982|GO:0009401|GO:0016021 ALX04_RS07955 0fbe2df25817a0581c997299bc472932 267 Pfam PF13350 Tyrosine phosphatase family 12 267 2.9E-64 T 28-03-2018 IPR026893 Tyrosine/serine-protein phosphatase IphP-type ALX04_RS07955 0fbe2df25817a0581c997299bc472932 267 ProSitePatterns PS00383 Tyrosine specific protein phosphatases active site. 156 166 - T 28-03-2018 IPR016130 Protein-tyrosine phosphatase, active site GO:0004725|GO:0016311 ALX04_RS07955 0fbe2df25817a0581c997299bc472932 267 SUPERFAMILY SSF52799 12 266 3.28E-54 T 28-03-2018 IPR029021 Protein-tyrosine phosphatase-like ALX04_RS07955 0fbe2df25817a0581c997299bc472932 267 Gene3D G3DSA:3.90.190.10 32 238 8.7E-18 T 28-03-2018 IPR029021 Protein-tyrosine phosphatase-like ALX04_RS13040 0b1a3d21a5934a2afd007feeba2454fc 470 Pfam PF03577 Peptidase family C69 5 401 5.1E-148 T 28-03-2018 IPR005322 Peptidase C69, dipeptidase A GO:0006508|GO:0016805 ALX04_RS13040 0b1a3d21a5934a2afd007feeba2454fc 470 Gene3D G3DSA:3.60.60.10 6 272 4.0E-47 T 28-03-2018 ALX04_RS07900 a39e31f8e6153eba228161467ca3d9d7 341 Hamap MF_00741 Phosphoribosylformylglycinamidine cyclo-ligase [purM]. 3 333 38.788 T 28-03-2018 IPR004733 Phosphoribosylformylglycinamidine cyclo-ligase GO:0004641|GO:0005737|GO:0006189 KEGG: 00230+6.3.3.1|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 ALX04_RS07900 a39e31f8e6153eba228161467ca3d9d7 341 Pfam PF00586 AIR synthase related protein, N-terminal domain 51 154 1.0E-14 T 28-03-2018 IPR016188 PurM-like, N-terminal domain ALX04_RS07900 a39e31f8e6153eba228161467ca3d9d7 341 Gene3D G3DSA:3.90.650.10 162 335 5.7E-51 T 28-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain ALX04_RS07900 a39e31f8e6153eba228161467ca3d9d7 341 SUPERFAMILY SSF56042 163 333 5.08E-49 T 28-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain ALX04_RS07900 a39e31f8e6153eba228161467ca3d9d7 341 Gene3D G3DSA:3.30.1330.10 22 152 1.2E-48 T 28-03-2018 IPR016188 PurM-like, N-terminal domain ALX04_RS07900 a39e31f8e6153eba228161467ca3d9d7 341 Pfam PF02769 AIR synthase related protein, C-terminal domain 167 330 3.6E-24 T 28-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain ALX04_RS07900 a39e31f8e6153eba228161467ca3d9d7 341 TIGRFAM TIGR00878 purM: phosphoribosylformylglycinamidine cyclo-ligase 4 328 2.1E-111 T 28-03-2018 IPR004733 Phosphoribosylformylglycinamidine cyclo-ligase GO:0004641|GO:0005737|GO:0006189 KEGG: 00230+6.3.3.1|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 ALX04_RS07900 a39e31f8e6153eba228161467ca3d9d7 341 SUPERFAMILY SSF55326 4 158 8.02E-39 T 28-03-2018 IPR016188 PurM-like, N-terminal domain ALX04_RS02465 375d01a0369af5a0c7a806b3225be59f 228 Pfam PF00072 Response regulator receiver domain 4 112 6.2E-26 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 ALX04_RS02465 375d01a0369af5a0c7a806b3225be59f 228 Pfam PF00486 Transcriptional regulatory protein, C terminal 152 225 4.8E-25 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 ALX04_RS02465 375d01a0369af5a0c7a806b3225be59f 228 Gene3D G3DSA:3.40.50.2300 1 126 6.4E-36 T 28-03-2018 ALX04_RS02465 375d01a0369af5a0c7a806b3225be59f 228 SUPERFAMILY SSF52172 2 130 1.22E-40 T 28-03-2018 IPR011006 CheY-like superfamily ALX04_RS02465 375d01a0369af5a0c7a806b3225be59f 228 SUPERFAMILY SSF46894 126 226 1.39E-29 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 ALX04_RS02465 375d01a0369af5a0c7a806b3225be59f 228 SMART SM00448 2 112 3.5E-40 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 ALX04_RS02465 375d01a0369af5a0c7a806b3225be59f 228 SMART SM00862 151 226 6.7E-25 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 ALX04_RS02465 375d01a0369af5a0c7a806b3225be59f 228 Gene3D G3DSA:1.10.10.10 127 228 5.6E-26 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS11505 f3075b4d1b296b32d726ca990c08c00c 140 Gene3D G3DSA:1.10.150.20 58 123 0.074 T 28-03-2018 ALX04_RS11505 f3075b4d1b296b32d726ca990c08c00c 140 SMART SM00530 7 62 6.1E-11 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 ALX04_RS11505 f3075b4d1b296b32d726ca990c08c00c 140 Gene3D G3DSA:1.10.260.40 3 57 8.1E-17 T 28-03-2018 ALX04_RS11505 f3075b4d1b296b32d726ca990c08c00c 140 Pfam PF01381 Helix-turn-helix 8 62 2.5E-11 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 ALX04_RS11505 f3075b4d1b296b32d726ca990c08c00c 140 SUPERFAMILY SSF47413 3 68 2.82E-16 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 ALX04_RS07390 7b9871b22317e14ce2cc28ee1709d9cc 717 Gene3D G3DSA:3.40.720.10 245 557 5.2E-39 T 28-03-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 ALX04_RS07390 7b9871b22317e14ce2cc28ee1709d9cc 717 SUPERFAMILY SSF53649 249 647 1.16E-72 T 28-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 ALX04_RS07390 7b9871b22317e14ce2cc28ee1709d9cc 717 Pfam PF00884 Sulfatase 251 547 4.2E-36 T 28-03-2018 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 ALX04_RS07390 7b9871b22317e14ce2cc28ee1709d9cc 717 PIRSF PIRSF005091 1 635 7.3E-240 T 28-03-2018 IPR012160 Lipoteichoic acid synthase-like ALX04_RS06600 893832ed1b078786bbb1f2f10c2ae9bc 613 Gene3D G3DSA:1.20.5.50 138 262 1.5E-5 T 28-03-2018 ALX04_RS06600 893832ed1b078786bbb1f2f10c2ae9bc 613 SUPERFAMILY SSF56300 537 608 1.12E-24 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like ALX04_RS06600 893832ed1b078786bbb1f2f10c2ae9bc 613 SUPERFAMILY SSF56300 287 509 1.12E-24 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like ALX04_RS06600 893832ed1b078786bbb1f2f10c2ae9bc 613 Pfam PF00149 Calcineurin-like phosphoesterase 288 550 1.6E-8 T 28-03-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 ALX04_RS06600 893832ed1b078786bbb1f2f10c2ae9bc 613 Gene3D G3DSA:3.60.21.10 283 607 8.0E-23 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like ALX04_RS03895 dad8723567889284027b2078d7989f68 265 Gene3D G3DSA:3.40.50.1000 2 265 6.8E-31 T 28-03-2018 IPR023214 HAD-like domain ALX04_RS03895 dad8723567889284027b2078d7989f68 265 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 5 233 4.4E-21 T 28-03-2018 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 ALX04_RS03895 dad8723567889284027b2078d7989f68 265 SUPERFAMILY SSF56784 4 265 7.22E-60 T 28-03-2018 IPR023214 HAD-like domain ALX04_RS03895 dad8723567889284027b2078d7989f68 265 TIGRFAM TIGR00099 Cof-subfamily: Cof-like hydrolase 5 260 5.9E-45 T 28-03-2018 IPR000150 Cof family GO:0016787 ALX04_RS03895 dad8723567889284027b2078d7989f68 265 ProSitePatterns PS01229 Hypothetical cof family signature 2. 214 236 - T 28-03-2018 ALX04_RS03895 dad8723567889284027b2078d7989f68 265 Pfam PF08282 haloacid dehalogenase-like hydrolase 6 259 4.0E-51 T 28-03-2018 IPR023214 HAD-like domain ALX04_RS08200 c0b74309c78ebc14965f1bb4f99d73f6 308 SUPERFAMILY SSF103481 207 296 7.19E-10 T 28-03-2018 ALX04_RS08200 c0b74309c78ebc14965f1bb4f99d73f6 308 SUPERFAMILY SSF103481 47 150 2.49E-8 T 28-03-2018 ALX04_RS08200 c0b74309c78ebc14965f1bb4f99d73f6 308 Pfam PF00892 EamA-like transporter family 159 291 6.3E-21 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 ALX04_RS08200 c0b74309c78ebc14965f1bb4f99d73f6 308 Pfam PF00892 EamA-like transporter family 8 147 8.6E-17 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 ALX04_RS15165 6e067d4acb7aa01b56cd6bef55b2aefb 163 TIGRFAM TIGR00830 PTBA: PTS system, glucose subfamily, IIA component 14 137 2.6E-37 T 28-03-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 ALX04_RS15165 6e067d4acb7aa01b56cd6bef55b2aefb 163 Gene3D G3DSA:2.70.70.10 3 162 9.2E-48 T 28-03-2018 ALX04_RS15165 6e067d4acb7aa01b56cd6bef55b2aefb 163 ProSitePatterns PS00371 PTS EIIA domains phosphorylation site signature 1. 79 91 - T 28-03-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 ALX04_RS15165 6e067d4acb7aa01b56cd6bef55b2aefb 163 SUPERFAMILY SSF51261 5 141 2.44E-43 T 28-03-2018 IPR011055 Duplicated hybrid motif ALX04_RS15165 6e067d4acb7aa01b56cd6bef55b2aefb 163 Pfam PF00358 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 13 137 7.2E-44 T 28-03-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 ALX04_RS14160 4f8a26397a99b2cb1c64d394acd79691 133 Pfam PF00364 Biotin-requiring enzyme 62 129 3.1E-12 T 28-03-2018 IPR000089 Biotin/lipoyl attachment ALX04_RS14160 4f8a26397a99b2cb1c64d394acd79691 133 Gene3D G3DSA:2.40.50.100 60 89 7.3E-4 T 28-03-2018 ALX04_RS14160 4f8a26397a99b2cb1c64d394acd79691 133 SUPERFAMILY SSF51230 53 129 1.49E-15 T 28-03-2018 IPR011053 Single hybrid motif ALX04_RS14160 4f8a26397a99b2cb1c64d394acd79691 133 Gene3D G3DSA:2.40.50.100 90 132 8.2E-11 T 28-03-2018 ALX04_RS14240 60cb0448f36057cd0e283a224114a61c 391 SUPERFAMILY SSF103473 6 122 1.02E-5 T 28-03-2018 IPR020846 Major facilitator superfamily domain ALX04_RS14240 60cb0448f36057cd0e283a224114a61c 391 SUPERFAMILY SSF88723 165 293 2.5E-26 T 28-03-2018 IPR029060 PIN domain-like ALX04_RS14240 60cb0448f36057cd0e283a224114a61c 391 SMART SM00670 165 272 9.5E-12 T 28-03-2018 IPR002716 PIN domain ALX04_RS14240 60cb0448f36057cd0e283a224114a61c 391 Gene3D G3DSA:3.40.50.1010 160 296 8.8E-29 T 28-03-2018 IPR029060 PIN domain-like ALX04_RS00155 23b1b1747edaeaaf6cd74a9bcb7da0e1 108 Pfam PF05437 Branched-chain amino acid transport protein (AzlD) 5 103 4.3E-24 T 28-03-2018 IPR008407 Branched-chain amino acid transport, AzlD ALX04_RS00555 8a588f2100c263750177690b64b79523 295 SUPERFAMILY SSF52540 3 239 9.2E-62 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase ALX04_RS00555 8a588f2100c263750177690b64b79523 295 TIGRFAM TIGR04521 ECF_ATPase_2: energy-coupling factor transporter ATPase 3 279 9.2E-125 T 28-03-2018 IPR030946 Energy-coupling factor transporter ATP-binding protein EcfA2 ALX04_RS00555 8a588f2100c263750177690b64b79523 295 Gene3D G3DSA:3.40.50.300 1 264 5.0E-69 T 28-03-2018 ALX04_RS00555 8a588f2100c263750177690b64b79523 295 SMART SM00382 32 223 1.6E-11 T 28-03-2018 IPR003593 AAA+ ATPase domain ALX04_RS00555 8a588f2100c263750177690b64b79523 295 Pfam PF00005 ABC transporter 23 174 1.4E-31 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 ALX04_RS00555 8a588f2100c263750177690b64b79523 295 ProSitePatterns PS00211 ABC transporters family signature. 146 160 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 ALX04_RS03220 e2e776f7294b3c086a99043e6348cb73 479 Gene3D G3DSA:3.60.60.10 12 273 8.9E-54 T 28-03-2018 ALX04_RS03220 e2e776f7294b3c086a99043e6348cb73 479 Pfam PF03577 Peptidase family C69 11 410 3.9E-144 T 28-03-2018 IPR005322 Peptidase C69, dipeptidase A GO:0006508|GO:0016805 ALX04_RS09710 6b5077edc51fd87acbb56584f6a15ebf 724 Gene3D G3DSA:2.20.28.20 11 37 3.1E-4 T 28-03-2018 ALX04_RS09710 6b5077edc51fd87acbb56584f6a15ebf 724 TIGRFAM TIGR03238 dnd_assoc_3: DNA phosphorothioation-dependent restriction protein DptF 191 719 2.0E-67 T 28-03-2018 IPR017647 DNA phosphorothioation-dependent restriction protein DptF ALX04_RS09710 6b5077edc51fd87acbb56584f6a15ebf 724 Pfam PF13240 zinc-ribbon domain 11 33 2.8E-7 T 28-03-2018 IPR026870 Zinc-ribbon domain Reactome: R-HSA-202670 ALX04_RS06975 f3101a7a5dd0faf913834bc298c3daf6 385 Gene3D G3DSA:1.10.150.130 62 175 2.2E-13 T 28-03-2018 IPR023109 Integrase/recombinase, N-terminal ALX04_RS06975 f3101a7a5dd0faf913834bc298c3daf6 385 Pfam PF14659 Phage integrase, N-terminal SAM-like domain 70 125 4.7E-17 T 28-03-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 ALX04_RS06975 f3101a7a5dd0faf913834bc298c3daf6 385 SUPERFAMILY SSF56349 70 376 1.62E-60 T 28-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 ALX04_RS06975 f3101a7a5dd0faf913834bc298c3daf6 385 Pfam PF14657 Arm DNA-binding domain 15 56 6.1E-14 T 28-03-2018 IPR028259 AP2-like integrase, N-terminal domain ALX04_RS06975 f3101a7a5dd0faf913834bc298c3daf6 385 Pfam PF00589 Phage integrase family 179 369 6.8E-29 T 28-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 ALX04_RS06975 f3101a7a5dd0faf913834bc298c3daf6 385 Gene3D G3DSA:1.10.443.10 177 377 2.7E-40 T 28-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 ALX04_RS14595 708f86edfbd159fa9fec913c6364875e 121 Pfam PF04020 Mycobacterial 4 TMS phage holin, superfamily IV 2 108 4.0E-25 T 28-03-2018 IPR007165 Mycobacterial 4 TMS phage holin, superfamily IV ALX04_RS14500 612f66570895948eed9f80c5cc5609c0 611 Pfam PF13520 Amino acid permease 27 440 2.3E-32 T 28-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 ALX04_RS09075 b7cc53070ba33086b6c2db26439e52f7 125 TIGRFAM TIGR01167 LPXTG_anchor: LPXTG cell wall anchor domain 86 111 1.7E-4 T 28-03-2018 ALX04_RS09065 4ec5379163813980bdf0bf6c6afdc451 321 SUPERFAMILY SSF53822 42 264 4.48E-11 T 28-03-2018 IPR028082 Periplasmic binding protein-like I ALX04_RS09065 4ec5379163813980bdf0bf6c6afdc451 321 Gene3D G3DSA:3.40.50.2300 159 294 1.1E-17 T 28-03-2018 ALX04_RS09065 4ec5379163813980bdf0bf6c6afdc451 321 Pfam PF04392 ABC transporter substrate binding protein 32 314 6.6E-75 T 28-03-2018 IPR007487 ABC transporter, substrate-binding protein ALX04_RS09065 4ec5379163813980bdf0bf6c6afdc451 321 Gene3D G3DSA:3.40.50.2300 29 158 1.6E-12 T 28-03-2018 ALX04_RS13000 1e429d191b900e0a3a88d20738b99fdb 117 SUPERFAMILY SSF46785 4 78 4.34E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS13000 1e429d191b900e0a3a88d20738b99fdb 117 Gene3D G3DSA:1.10.10.10 1 76 1.1E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS13000 1e429d191b900e0a3a88d20738b99fdb 117 SMART SM00345 15 74 1.3E-18 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 ALX04_RS13000 1e429d191b900e0a3a88d20738b99fdb 117 Pfam PF00392 Bacterial regulatory proteins, gntR family 12 74 3.7E-15 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 ALX04_RS01435 69dc172ad7277befc77012ac023e1613 412 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 149 162 6.9E-11 T 28-03-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 ALX04_RS01435 69dc172ad7277befc77012ac023e1613 412 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 65 76 6.9E-11 T 28-03-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 ALX04_RS01435 69dc172ad7277befc77012ac023e1613 412 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 122 139 6.9E-11 T 28-03-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 ALX04_RS01435 69dc172ad7277befc77012ac023e1613 412 Pfam PF00768 D-alanyl-D-alanine carboxypeptidase 38 281 1.2E-59 T 28-03-2018 IPR001967 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A, N-terminal GO:0006508|GO:0009002 ALX04_RS01435 69dc172ad7277befc77012ac023e1613 412 SUPERFAMILY SSF56601 11 284 2.35E-54 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like ALX04_RS01435 69dc172ad7277befc77012ac023e1613 412 Gene3D G3DSA:3.40.710.10 23 307 6.1E-34 T 28-03-2018 ALX04_RS00775 4ebe9c5f3ab62fd9f23715596309b290 475 Pfam PF13520 Amino acid permease 27 435 3.7E-52 T 28-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 ALX04_RS00775 4ebe9c5f3ab62fd9f23715596309b290 475 PIRSF PIRSF006060 9 475 6.8E-84 T 28-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 ALX04_RS15545 53063d982e0c404cd1081a0f8777148b 49 Gene3D G3DSA:1.10.10.60 11 49 1.0E-14 T 28-03-2018 ALX04_RS15545 53063d982e0c404cd1081a0f8777148b 49 Pfam PF13936 Helix-turn-helix domain 11 49 5.8E-14 T 28-03-2018 IPR025246 Transposase IS30-like HTH domain ALX04_RS00430 a519b7306089484cdf420a3bdacc6c0f 122 Pfam PF00238 Ribosomal protein L14p/L23e 2 122 6.7E-50 T 28-03-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 ALX04_RS00430 a519b7306089484cdf420a3bdacc6c0f 122 Gene3D G3DSA:2.40.150.20 1 122 6.4E-49 T 28-03-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 ALX04_RS00430 a519b7306089484cdf420a3bdacc6c0f 122 Hamap MF_01367 50S ribosomal protein L14 [rplN]. 1 122 25.508 T 28-03-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 ALX04_RS00430 a519b7306089484cdf420a3bdacc6c0f 122 ProSitePatterns PS00049 Ribosomal protein L14 signature. 60 86 - T 28-03-2018 IPR019972 Ribosomal protein L14P, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 ALX04_RS00430 a519b7306089484cdf420a3bdacc6c0f 122 TIGRFAM TIGR01067 rplN_bact: ribosomal protein uL14 1 122 2.0E-53 T 28-03-2018 IPR005745 Ribosomal protein L14P, bacterial-type GO:0003735|GO:0006412|GO:0015934 ALX04_RS00430 a519b7306089484cdf420a3bdacc6c0f 122 SUPERFAMILY SSF50193 2 122 6.02E-47 T 28-03-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 ALX04_RS00430 a519b7306089484cdf420a3bdacc6c0f 122 SMART SM01374 1 122 4.8E-79 T 28-03-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 ALX04_RS08915 493f0c6716b1069c6f3ea8cb60705ff0 334 PIRSF PIRSF006621 9 334 5.3E-80 T 28-03-2018 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 ALX04_RS08915 493f0c6716b1069c6f3ea8cb60705ff0 334 Gene3D G3DSA:1.10.1200.80 260 334 7.8E-11 T 28-03-2018 IPR024036 tRNA-dihydrouridine synthase, putative, C-terminal GO:0016491|GO:0055114 ALX04_RS08915 493f0c6716b1069c6f3ea8cb60705ff0 334 ProSitePatterns PS01136 Uncharacterized protein family UPF0034 signature. 108 126 - T 28-03-2018 IPR018517 tRNA-dihydrouridine synthase, conserved site GO:0008033|GO:0017150|GO:0050660|GO:0055114 ALX04_RS08915 493f0c6716b1069c6f3ea8cb60705ff0 334 Gene3D G3DSA:3.20.20.70 18 259 4.9E-31 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 ALX04_RS08915 493f0c6716b1069c6f3ea8cb60705ff0 334 SUPERFAMILY SSF51395 21 329 1.17E-54 T 28-03-2018 ALX04_RS08915 493f0c6716b1069c6f3ea8cb60705ff0 334 Pfam PF01207 Dihydrouridine synthase (Dus) 24 324 7.7E-49 T 28-03-2018 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 ALX04_RS14065 cab750f172965c823d2243f2f9ad364e 245 Pfam PF03808 Glycosyl transferase WecB/TagA/CpsF family 63 226 3.1E-58 T 28-03-2018 IPR004629 Glycosyl transferase WecB/TagA/CpsF GO:0009058 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622 ALX04_RS14065 cab750f172965c823d2243f2f9ad364e 245 Hamap MF_02070 N-acetylglucosaminyldiphosphoundecaprenol N-acetyl-beta-D-mannosaminyltransferase. 6 241 62.029 T 28-03-2018 IPR034714 N-acetylglucosaminyldiphosphoundecaprenol N-acetyl-beta-D-mannosaminyltransferase GO:0047244 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622|MetaCyc: PWY-7815|MetaCyc: PWY-7816|MetaCyc: PWY-7819 ALX04_RS14065 cab750f172965c823d2243f2f9ad364e 245 TIGRFAM TIGR00696 wecG_tagA_cpsF: glycosyltransferase, WecB/TagA/CpsF family 59 232 2.5E-55 T 28-03-2018 IPR004629 Glycosyl transferase WecB/TagA/CpsF GO:0009058 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622 ALX04_RS11375 37f5bc3abae7325f22a78dfdc60f141d 420 Gene3D G3DSA:3.30.565.10 264 400 2.2E-8 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain ALX04_RS11375 37f5bc3abae7325f22a78dfdc60f141d 420 SUPERFAMILY SSF55874 276 413 3.24E-7 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain ALX04_RS11375 37f5bc3abae7325f22a78dfdc60f141d 420 Pfam PF14501 GHKL domain 311 411 2.2E-11 T 28-03-2018 IPR032834 Sensor histidine kinase NatK, C-terminal domain ALX04_RS11375 37f5bc3abae7325f22a78dfdc60f141d 420 Gene3D G3DSA:1.10.287.130 199 259 5.4E-9 T 28-03-2018 ALX04_RS03920 0269d60dc1b6c2117f0162f658c7bafa 429 SUPERFAMILY SSF50249 10 125 7.86E-19 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold ALX04_RS03920 0269d60dc1b6c2117f0162f658c7bafa 429 SUPERFAMILY SSF50249 272 362 9.7E-25 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold ALX04_RS03920 0269d60dc1b6c2117f0162f658c7bafa 429 SMART SM00316 116 183 2.9E-12 T 28-03-2018 IPR022967 RNA-binding domain, S1 ALX04_RS03920 0269d60dc1b6c2117f0162f658c7bafa 429 SMART SM00316 287 358 1.1E-26 T 28-03-2018 IPR022967 RNA-binding domain, S1 ALX04_RS03920 0269d60dc1b6c2117f0162f658c7bafa 429 SMART SM00316 24 100 1.3E-9 T 28-03-2018 IPR022967 RNA-binding domain, S1 ALX04_RS03920 0269d60dc1b6c2117f0162f658c7bafa 429 SMART SM00316 202 272 3.6E-28 T 28-03-2018 IPR022967 RNA-binding domain, S1 ALX04_RS03920 0269d60dc1b6c2117f0162f658c7bafa 429 Gene3D G3DSA:2.40.50.140 2 105 1.1E-12 T 28-03-2018 ALX04_RS03920 0269d60dc1b6c2117f0162f658c7bafa 429 SUPERFAMILY SSF50249 202 287 1.57E-28 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold ALX04_RS03920 0269d60dc1b6c2117f0162f658c7bafa 429 SUPERFAMILY SSF50249 103 186 3.43E-16 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold ALX04_RS03920 0269d60dc1b6c2117f0162f658c7bafa 429 PRINTS PR00681 Ribosomal protein S1 signature 167 187 2.7E-45 T 28-03-2018 ALX04_RS03920 0269d60dc1b6c2117f0162f658c7bafa 429 PRINTS PR00681 Ribosomal protein S1 signature 26 44 2.7E-45 T 28-03-2018 ALX04_RS03920 0269d60dc1b6c2117f0162f658c7bafa 429 PRINTS PR00681 Ribosomal protein S1 signature 302 321 2.7E-45 T 28-03-2018 ALX04_RS03920 0269d60dc1b6c2117f0162f658c7bafa 429 PRINTS PR00681 Ribosomal protein S1 signature 138 155 2.7E-45 T 28-03-2018 ALX04_RS03920 0269d60dc1b6c2117f0162f658c7bafa 429 PRINTS PR00681 Ribosomal protein S1 signature 341 359 2.7E-45 T 28-03-2018 ALX04_RS03920 0269d60dc1b6c2117f0162f658c7bafa 429 PRINTS PR00681 Ribosomal protein S1 signature 121 137 2.7E-45 T 28-03-2018 ALX04_RS03920 0269d60dc1b6c2117f0162f658c7bafa 429 PRINTS PR00681 Ribosomal protein S1 signature 224 245 2.7E-45 T 28-03-2018 ALX04_RS03920 0269d60dc1b6c2117f0162f658c7bafa 429 Gene3D G3DSA:2.40.50.140 111 189 7.1E-14 T 28-03-2018 ALX04_RS03920 0269d60dc1b6c2117f0162f658c7bafa 429 Pfam PF00575 S1 RNA binding domain 115 183 3.1E-13 T 28-03-2018 IPR003029 S1 domain GO:0003676 ALX04_RS03920 0269d60dc1b6c2117f0162f658c7bafa 429 Pfam PF00575 S1 RNA binding domain 201 272 1.5E-26 T 28-03-2018 IPR003029 S1 domain GO:0003676 ALX04_RS03920 0269d60dc1b6c2117f0162f658c7bafa 429 Pfam PF00575 S1 RNA binding domain 287 358 2.5E-23 T 28-03-2018 IPR003029 S1 domain GO:0003676 ALX04_RS03920 0269d60dc1b6c2117f0162f658c7bafa 429 Pfam PF00575 S1 RNA binding domain 23 83 1.4E-8 T 28-03-2018 IPR003029 S1 domain GO:0003676 ALX04_RS03920 0269d60dc1b6c2117f0162f658c7bafa 429 Gene3D G3DSA:2.40.50.140 290 393 2.1E-27 T 28-03-2018 ALX04_RS03920 0269d60dc1b6c2117f0162f658c7bafa 429 Gene3D G3DSA:2.40.50.140 204 289 7.0E-28 T 28-03-2018 ALX04_RS07560 b603030fc4c2cf98c554670825523ef4 261 SUPERFAMILY SSF53474 7 257 1.32E-28 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold ALX04_RS07560 b603030fc4c2cf98c554670825523ef4 261 Pfam PF00326 Prolyl oligopeptidase family 69 218 8.8E-8 T 28-03-2018 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 ALX04_RS07560 b603030fc4c2cf98c554670825523ef4 261 Gene3D G3DSA:3.40.50.1820 6 259 2.0E-27 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold ALX04_RS16055 9c35c9c67270a6b45f01c3e53a2b35ac 308 Pfam PF00268 Ribonucleotide reductase, small chain 9 266 1.1E-37 T 28-03-2018 IPR000358 Ribonucleotide reductase small subunit family GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 ALX04_RS16055 9c35c9c67270a6b45f01c3e53a2b35ac 308 SUPERFAMILY SSF47240 6 267 1.22E-39 T 28-03-2018 IPR009078 Ferritin-like superfamily ALX04_RS16055 9c35c9c67270a6b45f01c3e53a2b35ac 308 Gene3D G3DSA:1.10.620.20 6 284 5.5E-34 T 28-03-2018 ALX04_RS11245 a1016cb6ba1800d3d3cf472fba48712b 152 SUPERFAMILY SSF55804 1 145 3.92E-29 T 28-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 ALX04_RS11245 a1016cb6ba1800d3d3cf472fba48712b 152 Gene3D G3DSA:3.40.930.10 2 148 3.5E-27 T 28-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 ALX04_RS11245 a1016cb6ba1800d3d3cf472fba48712b 152 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 5 146 2.5E-26 T 28-03-2018 IPR002178 PTS EIIA type-2 domain ALX04_RS01150 5b5fd3a748751e8ba67369dd517a5997 289 TIGRFAM TIGR01207 rmlA: glucose-1-phosphate thymidylyltransferase 2 286 2.3E-149 T 28-03-2018 IPR005907 Glucose-1-phosphate thymidylyltransferase, short form GO:0008879|GO:0045226 KEGG: 00521+2.7.7.24|KEGG: 00523+2.7.7.24|KEGG: 00525+2.7.7.24|MetaCyc: PWY-3221|MetaCyc: PWY-6808|MetaCyc: PWY-6942|MetaCyc: PWY-6953|MetaCyc: PWY-6973|MetaCyc: PWY-6974|MetaCyc: PWY-6976|MetaCyc: PWY-7104|MetaCyc: PWY-7301|MetaCyc: PWY-7312|MetaCyc: PWY-7315|MetaCyc: PWY-7316|MetaCyc: PWY-7318|MetaCyc: PWY-7413|MetaCyc: PWY-7414|MetaCyc: PWY-7440|MetaCyc: PWY-7657|MetaCyc: PWY-7688|MetaCyc: PWY-7814 ALX04_RS01150 5b5fd3a748751e8ba67369dd517a5997 289 SUPERFAMILY SSF53448 1 286 1.26E-90 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases ALX04_RS01150 5b5fd3a748751e8ba67369dd517a5997 289 Gene3D G3DSA:3.90.550.10 1 289 1.3E-68 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases ALX04_RS01150 5b5fd3a748751e8ba67369dd517a5997 289 Pfam PF00483 Nucleotidyl transferase 2 238 2.0E-69 T 28-03-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 ALX04_RS05040 32bd2443ca8b78f1eb55a2263db7f639 253 Gene3D G3DSA:3.40.50.150 4 228 7.2E-13 T 28-03-2018 ALX04_RS05040 32bd2443ca8b78f1eb55a2263db7f639 253 SUPERFAMILY SSF53335 14 185 2.25E-17 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase ALX04_RS08365 043346393e7778a029ec45cf8d9db043 183 Pfam PF12822 ECF transporter, substrate-specific component 8 172 3.1E-12 T 28-03-2018 IPR024529 ECF transporter, substrate-specific component GO:0005215 ALX04_RS02620 93fd37e4273fb77e6608591507f286fe 244 Gene3D G3DSA:3.20.20.190 2 243 3.7E-57 T 28-03-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 ALX04_RS02620 93fd37e4273fb77e6608591507f286fe 244 SUPERFAMILY SSF51695 3 238 4.71E-61 T 28-03-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 ALX04_RS02620 93fd37e4273fb77e6608591507f286fe 244 Pfam PF03009 Glycerophosphoryl diester phosphodiesterase family 8 232 1.8E-39 T 28-03-2018 IPR030395 Glycerophosphodiester phosphodiesterase domain GO:0006629|GO:0008081 ALX04_RS09840 79e336791f3854b8dd1f122ffe1dbf03 261 Pfam PF03591 AzlC protein 24 164 9.0E-30 T 28-03-2018 IPR011606 Branched-chain amino acid transport, permease ALX04_RS08800 a55e5c15f358ae5f028f44614cc159b6 401 Pfam PF02517 CAAX protease self-immunity 244 345 3.3E-13 T 28-03-2018 IPR003675 CAAX amino terminal protease GO:0016020 Reactome: R-HSA-5689880 ALX04_RS08800 a55e5c15f358ae5f028f44614cc159b6 401 PRINTS PR00173 Glutamate-aspartate symporter signature 76 96 9.8E-5 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 ALX04_RS08800 a55e5c15f358ae5f028f44614cc159b6 401 PRINTS PR00173 Glutamate-aspartate symporter signature 167 189 9.8E-5 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 ALX04_RS14660 56fe08ffdf7d7210c560b0c2a5fdd10b 185 PIRSF PIRSF026671 1 185 3.9E-55 T 28-03-2018 IPR000755 D-alanyl-D-alanine dipeptidase GO:0005618|GO:0006508|GO:0008237|GO:0016805 MetaCyc: PWY-6454|MetaCyc: PWY-6455 ALX04_RS14660 56fe08ffdf7d7210c560b0c2a5fdd10b 185 Hamap MF_01924 D-alanyl-D-alanine dipeptidase [ddpX]. 7 181 25.732 T 28-03-2018 IPR000755 D-alanyl-D-alanine dipeptidase GO:0005618|GO:0006508|GO:0008237|GO:0016805 MetaCyc: PWY-6454|MetaCyc: PWY-6455 ALX04_RS14660 56fe08ffdf7d7210c560b0c2a5fdd10b 185 SUPERFAMILY SSF55166 7 168 1.57E-47 T 28-03-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 ALX04_RS14660 56fe08ffdf7d7210c560b0c2a5fdd10b 185 Pfam PF01427 D-ala-D-ala dipeptidase 7 172 3.2E-30 T 28-03-2018 IPR000755 D-alanyl-D-alanine dipeptidase GO:0005618|GO:0006508|GO:0008237|GO:0016805 MetaCyc: PWY-6454|MetaCyc: PWY-6455 ALX04_RS14660 56fe08ffdf7d7210c560b0c2a5fdd10b 185 Gene3D G3DSA:3.30.1380.10 4 178 9.3E-44 T 28-03-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 ALX04_RS07855 f170eed4aa293f8dc5c4069a1c25c49d 427 PIRSF PIRSF005353 1 427 8.0E-159 T 28-03-2018 IPR026033 Purine permease PbuG-like ALX04_RS07855 f170eed4aa293f8dc5c4069a1c25c49d 427 Pfam PF00860 Permease family 11 387 7.0E-43 T 28-03-2018 IPR006043 Xanthine/uracil/vitamin C permease GO:0005215|GO:0006810|GO:0016020|GO:0055085 ALX04_RS13460 dca82895b9ad798ee41293794acc6a73 140 SUPERFAMILY SSF55961 4 136 8.7E-6 T 28-03-2018 ALX04_RS13460 dca82895b9ad798ee41293794acc6a73 140 Gene3D G3DSA:3.30.530.20 2 139 8.0E-7 T 28-03-2018 IPR023393 START-like domain ALX04_RS13460 dca82895b9ad798ee41293794acc6a73 140 Pfam PF11687 Domain of unknown function (DUF3284) 1 120 6.9E-33 T 28-03-2018 IPR021701 Protein of unknown function DUF3284 ALX04_RS03175 2c2c69cf2c853433781f1afc4a2d964f 161 Pfam PF03073 TspO/MBR family 15 158 2.0E-38 T 28-03-2018 IPR004307 TspO/MBR-related protein GO:0016021 ALX04_RS03175 2c2c69cf2c853433781f1afc4a2d964f 161 PIRSF PIRSF005859 2 161 1.2E-47 T 28-03-2018 IPR004307 TspO/MBR-related protein GO:0016021 ALX04_RS11560 a67408653d663f43de8c0b37f25d68ef 114 TIGRFAM TIGR00188 rnpA: ribonuclease P protein component 1 105 5.4E-24 T 28-03-2018 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 ALX04_RS11560 a67408653d663f43de8c0b37f25d68ef 114 Pfam PF00825 Ribonuclease P 1 106 1.1E-30 T 28-03-2018 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 ALX04_RS11560 a67408653d663f43de8c0b37f25d68ef 114 SUPERFAMILY SSF54211 1 113 6.32E-32 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold ALX04_RS11560 a67408653d663f43de8c0b37f25d68ef 114 ProDom PD003629 P RIBONUCLEASE COMPONENT HYDROLASE RNASE C5 RNASEP RNA-BINDING PROCESSING ENDONUCLEASE 8 86 7.0E-41 T 28-03-2018 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 ALX04_RS11560 a67408653d663f43de8c0b37f25d68ef 114 Gene3D G3DSA:3.30.230.10 1 114 2.4E-31 T 28-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup ALX04_RS11560 a67408653d663f43de8c0b37f25d68ef 114 Hamap MF_00227 Ribonuclease P protein component [rnpA]. 1 111 17.628 T 28-03-2018 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 ALX04_RS07305 6e41309e4aeab188b6f61f73cc0cfbf2 428 PIRSF PIRSF000099 1 426 1.8E-164 T 28-03-2018 IPR022695 Histidinol dehydrogenase, monofunctional GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 ALX04_RS07305 6e41309e4aeab188b6f61f73cc0cfbf2 428 ProSitePatterns PS00611 Histidinol dehydrogenase signature. 225 257 - T 28-03-2018 IPR001692 Histidinol dehydrogenase, conserved site GO:0000105|GO:0004399|GO:0055114 KEGG: 00340+1.1.1.23 ALX04_RS07305 6e41309e4aeab188b6f61f73cc0cfbf2 428 Pfam PF00815 Histidinol dehydrogenase 20 423 1.0E-168 T 28-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 ALX04_RS07305 6e41309e4aeab188b6f61f73cc0cfbf2 428 Hamap MF_01024 Histidinol dehydrogenase [hisD]. 1 423 43.095 T 28-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 ALX04_RS07305 6e41309e4aeab188b6f61f73cc0cfbf2 428 Gene3D G3DSA:3.40.50.1980 24 221 1.1E-86 T 28-03-2018 ALX04_RS07305 6e41309e4aeab188b6f61f73cc0cfbf2 428 TIGRFAM TIGR00069 hisD: histidinol dehydrogenase 31 422 5.8E-165 T 28-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 ALX04_RS07305 6e41309e4aeab188b6f61f73cc0cfbf2 428 SUPERFAMILY SSF53720 27 426 1.0E-84 T 28-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 ALX04_RS07305 6e41309e4aeab188b6f61f73cc0cfbf2 428 Gene3D G3DSA:3.40.50.1980 222 367 6.7E-65 T 28-03-2018 ALX04_RS07305 6e41309e4aeab188b6f61f73cc0cfbf2 428 PRINTS PR00083 Histidinol dehydrogenase signature 132 158 4.9E-88 T 28-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 ALX04_RS07305 6e41309e4aeab188b6f61f73cc0cfbf2 428 PRINTS PR00083 Histidinol dehydrogenase signature 316 341 4.9E-88 T 28-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 ALX04_RS07305 6e41309e4aeab188b6f61f73cc0cfbf2 428 PRINTS PR00083 Histidinol dehydrogenase signature 31 55 4.9E-88 T 28-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 ALX04_RS07305 6e41309e4aeab188b6f61f73cc0cfbf2 428 PRINTS PR00083 Histidinol dehydrogenase signature 196 221 4.9E-88 T 28-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 ALX04_RS07305 6e41309e4aeab188b6f61f73cc0cfbf2 428 PRINTS PR00083 Histidinol dehydrogenase signature 166 192 4.9E-88 T 28-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 ALX04_RS07305 6e41309e4aeab188b6f61f73cc0cfbf2 428 PRINTS PR00083 Histidinol dehydrogenase signature 225 246 4.9E-88 T 28-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 ALX04_RS07305 6e41309e4aeab188b6f61f73cc0cfbf2 428 PRINTS PR00083 Histidinol dehydrogenase signature 247 266 4.9E-88 T 28-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 ALX04_RS07305 6e41309e4aeab188b6f61f73cc0cfbf2 428 PRINTS PR00083 Histidinol dehydrogenase signature 357 375 4.9E-88 T 28-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 ALX04_RS11465 dd708fe0805aa3194aba85d83c4b5238 332 Gene3D G3DSA:3.40.50.2300 63 172 6.6E-30 T 28-03-2018 ALX04_RS11465 dd708fe0805aa3194aba85d83c4b5238 332 SUPERFAMILY SSF53822 65 329 1.46E-74 T 28-03-2018 IPR028082 Periplasmic binding protein-like I ALX04_RS11465 dd708fe0805aa3194aba85d83c4b5238 332 Pfam PF00356 Bacterial regulatory proteins, lacI family 7 53 1.3E-13 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 ALX04_RS11465 dd708fe0805aa3194aba85d83c4b5238 332 Gene3D G3DSA:1.10.260.40 6 62 1.5E-16 T 28-03-2018 ALX04_RS11465 dd708fe0805aa3194aba85d83c4b5238 332 SMART SM00354 5 76 4.0E-21 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 ALX04_RS11465 dd708fe0805aa3194aba85d83c4b5238 332 SUPERFAMILY SSF47413 4 64 8.94E-13 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 ALX04_RS11465 dd708fe0805aa3194aba85d83c4b5238 332 Pfam PF13377 Periplasmic binding protein-like domain 174 328 7.3E-31 T 28-03-2018 ALX04_RS11465 dd708fe0805aa3194aba85d83c4b5238 332 Gene3D G3DSA:3.40.50.2300 173 331 4.9E-40 T 28-03-2018 ALX04_RS07375 927e13ecfd57ba47932e745143edc7f2 894 Gene3D G3DSA:3.90.20.10 423 631 1.3E-5 T 28-03-2018 ALX04_RS07375 927e13ecfd57ba47932e745143edc7f2 894 Gene3D G3DSA:1.20.1640.10 662 867 1.2E-4 T 28-03-2018 ALX04_RS07375 927e13ecfd57ba47932e745143edc7f2 894 Gene3D G3DSA:1.20.1640.10 123 263 1.3E-6 T 28-03-2018 ALX04_RS07375 927e13ecfd57ba47932e745143edc7f2 894 Pfam PF03176 MMPL family 51 235 2.4E-9 T 28-03-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 ALX04_RS12145 892857d93b14163e8ce405ceb0cb2ca2 410 Gene3D G3DSA:1.20.1250.20 8 205 2.9E-35 T 28-03-2018 ALX04_RS12145 892857d93b14163e8ce405ceb0cb2ca2 410 SUPERFAMILY SSF103473 8 401 5.62E-71 T 28-03-2018 IPR020846 Major facilitator superfamily domain ALX04_RS12145 892857d93b14163e8ce405ceb0cb2ca2 410 Gene3D G3DSA:1.20.1250.20 206 403 6.8E-26 T 28-03-2018 ALX04_RS12145 892857d93b14163e8ce405ceb0cb2ca2 410 Pfam PF07690 Major Facilitator Superfamily 18 301 3.7E-39 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 ALX04_RS07695 5412573b817de934b4c7d99626e263b0 139 Gene3D G3DSA:2.60.40.790 1 139 1.9E-27 T 28-03-2018 IPR008978 HSP20-like chaperone ALX04_RS07695 5412573b817de934b4c7d99626e263b0 139 SUPERFAMILY SSF49764 29 138 4.19E-28 T 28-03-2018 IPR008978 HSP20-like chaperone ALX04_RS07695 5412573b817de934b4c7d99626e263b0 139 Pfam PF00011 Hsp20/alpha crystallin family 40 139 1.5E-19 T 28-03-2018 IPR002068 Alpha crystallin/Hsp20 domain ALX04_RS02575 e4a17b7f7dd9b00c0bf3456ba91f68af 678 Pfam PF03717 Penicillin-binding Protein dimerisation domain 67 296 1.7E-35 T 28-03-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 ALX04_RS02575 e4a17b7f7dd9b00c0bf3456ba91f68af 678 Gene3D G3DSA:3.90.1310.10 34 312 7.9E-31 T 28-03-2018 ALX04_RS02575 e4a17b7f7dd9b00c0bf3456ba91f68af 678 Gene3D G3DSA:3.40.710.10 313 678 6.5E-59 T 28-03-2018 ALX04_RS02575 e4a17b7f7dd9b00c0bf3456ba91f68af 678 SUPERFAMILY SSF56519 180 311 1.57E-31 T 28-03-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 ALX04_RS02575 e4a17b7f7dd9b00c0bf3456ba91f68af 678 SUPERFAMILY SSF56519 66 123 1.57E-31 T 28-03-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 ALX04_RS02575 e4a17b7f7dd9b00c0bf3456ba91f68af 678 SUPERFAMILY SSF56601 312 677 7.24E-51 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like ALX04_RS02575 e4a17b7f7dd9b00c0bf3456ba91f68af 678 Pfam PF00905 Penicillin binding protein transpeptidase domain 343 670 9.4E-55 T 28-03-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 ALX04_RS14700 03fd457177e382be53031c012e0c05e1 178 Pfam PF03729 Short repeat of unknown function (DUF308) 134 177 5.7E-5 T 28-03-2018 IPR005325 Protein of unknown function DUF308, membrane ALX04_RS14700 03fd457177e382be53031c012e0c05e1 178 Pfam PF03729 Short repeat of unknown function (DUF308) 76 137 0.019 T 28-03-2018 IPR005325 Protein of unknown function DUF308, membrane ALX04_RS14700 03fd457177e382be53031c012e0c05e1 178 Pfam PF03729 Short repeat of unknown function (DUF308) 16 87 2.2E-11 T 28-03-2018 IPR005325 Protein of unknown function DUF308, membrane ALX04_RS00580 678c69ebafd1a2c40a9745c07499ec69 289 SUPERFAMILY SSF82549 3 285 3.14E-79 T 28-03-2018 ALX04_RS00580 678c69ebafd1a2c40a9745c07499ec69 289 Gene3D G3DSA:3.30.1180.10 157 289 1.6E-34 T 28-03-2018 ALX04_RS00580 678c69ebafd1a2c40a9745c07499ec69 289 Pfam PF02645 Uncharacterised protein, DegV family COG1307 3 282 3.9E-71 T 28-03-2018 IPR003797 DegV ALX04_RS00580 678c69ebafd1a2c40a9745c07499ec69 289 TIGRFAM TIGR00762 DegV: EDD domain protein, DegV family 3 282 1.3E-82 T 28-03-2018 IPR003797 DegV ALX04_RS00580 678c69ebafd1a2c40a9745c07499ec69 289 Gene3D G3DSA:3.40.50.10170 1 156 2.0E-43 T 28-03-2018 ALX04_RS14565 8d2284313dacb24958a8b64fd8eab0e6 309 Gene3D G3DSA:1.10.3720.10 13 297 1.5E-39 T 28-03-2018 ALX04_RS14565 8d2284313dacb24958a8b64fd8eab0e6 309 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 105 302 1.0E-28 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 ALX04_RS14565 8d2284313dacb24958a8b64fd8eab0e6 309 SUPERFAMILY SSF161098 19 299 3.4E-37 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 ALX04_RS14565 8d2284313dacb24958a8b64fd8eab0e6 309 TIGRFAM TIGR02138 phosphate_pstC: phosphate ABC transporter, permease protein PstC 21 303 1.8E-88 T 28-03-2018 IPR011864 Phosphate ABC transporter, permease protein PstC GO:0005315|GO:0006817|GO:0016021 ALX04_RS15795 606b3854ce6f39b9af98049ef2b3641d 223 SUPERFAMILY SSF53098 158 223 1.97E-9 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 ALX04_RS15795 606b3854ce6f39b9af98049ef2b3641d 223 Pfam PF13936 Helix-turn-helix domain 4 42 3.5E-9 T 28-03-2018 IPR025246 Transposase IS30-like HTH domain ALX04_RS15795 606b3854ce6f39b9af98049ef2b3641d 223 Gene3D G3DSA:1.10.10.10 60 134 5.7E-4 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS15795 606b3854ce6f39b9af98049ef2b3641d 223 Gene3D G3DSA:3.30.420.10 149 223 5.7E-10 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 ALX04_RS15795 606b3854ce6f39b9af98049ef2b3641d 223 Gene3D G3DSA:1.10.10.60 2 48 6.3E-9 T 28-03-2018 ALX04_RS13970 3b404b9d4b1c750c5ac5f7c453b0d38d 472 Pfam PF05272 Virulence-associated protein E 134 326 1.9E-67 T 28-03-2018 IPR007936 Virulence-associated E ALX04_RS13970 3b404b9d4b1c750c5ac5f7c453b0d38d 472 Gene3D G3DSA:3.40.50.300 120 328 6.1E-7 T 28-03-2018 ALX04_RS13675 fc0df12be6d1dedb4026b57bfebf5e40 81 TIGRFAM TIGR00105 L31: ribosomal protein bL31 1 80 7.2E-18 T 28-03-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 ALX04_RS13675 fc0df12be6d1dedb4026b57bfebf5e40 81 PRINTS PR01249 Ribosomal protein L31 signature 60 78 6.4E-17 T 28-03-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 ALX04_RS13675 fc0df12be6d1dedb4026b57bfebf5e40 81 PRINTS PR01249 Ribosomal protein L31 signature 2 19 6.4E-17 T 28-03-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 ALX04_RS13675 fc0df12be6d1dedb4026b57bfebf5e40 81 PRINTS PR01249 Ribosomal protein L31 signature 45 60 6.4E-17 T 28-03-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 ALX04_RS13675 fc0df12be6d1dedb4026b57bfebf5e40 81 Hamap MF_00502 50S ribosomal protein L31 type B [rpmE2]. 1 81 26.243 T 28-03-2018 IPR027493 Ribosomal protein L31 type B GO:0003735|GO:0005622|GO:0005840|GO:0006412 ALX04_RS13675 fc0df12be6d1dedb4026b57bfebf5e40 81 Pfam PF01197 Ribosomal protein L31 1 79 4.9E-28 T 28-03-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 ALX04_RS13675 fc0df12be6d1dedb4026b57bfebf5e40 81 SUPERFAMILY SSF143800 1 80 1.06E-22 T 28-03-2018 IPR034704 L28p-like Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 ALX04_RS08290 aa906601615dbf6f8ffa01574093865f 171 Pfam PF07155 ECF-type riboflavin transporter, S component 8 162 2.6E-39 T 28-03-2018 IPR009825 ECF transporter, substrate-specific component-like GO:0016020 ALX04_RS13375 5b753cb5138fbefa9167f838f2b421d6 247 SMART SM00448 2 122 3.0E-6 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 ALX04_RS13375 5b753cb5138fbefa9167f838f2b421d6 247 Pfam PF04397 LytTr DNA-binding domain 151 244 4.9E-18 T 28-03-2018 IPR007492 LytTR DNA-binding domain GO:0003677 ALX04_RS13375 5b753cb5138fbefa9167f838f2b421d6 247 SUPERFAMILY SSF52172 38 126 1.17E-7 T 28-03-2018 IPR011006 CheY-like superfamily ALX04_RS13375 5b753cb5138fbefa9167f838f2b421d6 247 SMART SM00850 150 245 8.9E-15 T 28-03-2018 IPR007492 LytTR DNA-binding domain GO:0003677 ALX04_RS13375 5b753cb5138fbefa9167f838f2b421d6 247 Pfam PF00072 Response regulator receiver domain 6 122 9.6E-9 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 ALX04_RS13375 5b753cb5138fbefa9167f838f2b421d6 247 Gene3D G3DSA:3.40.50.2300 2 127 2.5E-7 T 28-03-2018 ALX04_RS13375 5b753cb5138fbefa9167f838f2b421d6 247 Gene3D G3DSA:2.40.50.40 140 211 3.6E-10 T 28-03-2018 ALX04_RS00645 65cbce0a2563ddc8a12ecf54786cf484 245 SUPERFAMILY SSF52540 2 225 2.71E-53 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase ALX04_RS00645 65cbce0a2563ddc8a12ecf54786cf484 245 Pfam PF00005 ABC transporter 18 162 2.9E-31 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 ALX04_RS00645 65cbce0a2563ddc8a12ecf54786cf484 245 SMART SM00382 26 240 1.8E-10 T 28-03-2018 IPR003593 AAA+ ATPase domain ALX04_RS00645 65cbce0a2563ddc8a12ecf54786cf484 245 ProSitePatterns PS00211 ABC transporters family signature. 135 149 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 ALX04_RS00645 65cbce0a2563ddc8a12ecf54786cf484 245 Gene3D G3DSA:3.40.50.300 1 237 1.1E-56 T 28-03-2018 ALX04_RS07445 f066028204acbb8b806db8549290aa47 312 SUPERFAMILY SSF47413 1 58 6.94E-16 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 ALX04_RS07445 f066028204acbb8b806db8549290aa47 312 Gene3D G3DSA:3.40.50.2300 162 303 3.2E-17 T 28-03-2018 ALX04_RS07445 f066028204acbb8b806db8549290aa47 312 Gene3D G3DSA:1.10.260.40 2 60 8.0E-20 T 28-03-2018 ALX04_RS07445 f066028204acbb8b806db8549290aa47 312 Pfam PF00532 Periplasmic binding proteins and sugar binding domain of LacI family 59 257 3.9E-23 T 28-03-2018 IPR001761 Periplasmic binding protein/LacI sugar binding domain ALX04_RS07445 f066028204acbb8b806db8549290aa47 312 Pfam PF00356 Bacterial regulatory proteins, lacI family 4 48 1.4E-18 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 ALX04_RS07445 f066028204acbb8b806db8549290aa47 312 Gene3D G3DSA:3.40.50.2300 61 161 2.7E-18 T 28-03-2018 ALX04_RS07445 f066028204acbb8b806db8549290aa47 312 SMART SM00354 1 71 3.4E-34 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 ALX04_RS07445 f066028204acbb8b806db8549290aa47 312 SUPERFAMILY SSF53822 58 307 7.71E-37 T 28-03-2018 IPR028082 Periplasmic binding protein-like I ALX04_RS01555 d01b80d2a41d588da06459a37c03a783 172 SUPERFAMILY SSF55729 3 169 6.28E-24 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase ALX04_RS01555 d01b80d2a41d588da06459a37c03a783 172 Pfam PF00583 Acetyltransferase (GNAT) family 52 149 3.8E-10 T 28-03-2018 IPR000182 GNAT domain GO:0008080 ALX04_RS01555 d01b80d2a41d588da06459a37c03a783 172 Gene3D G3DSA:3.40.630.30 1 172 2.9E-23 T 28-03-2018 ALX04_RS02130 64b1f424bdf894259e306d6c0626729c 661 Gene3D G3DSA:2.40.10.220 514 625 2.1E-8 T 28-03-2018 ALX04_RS02130 64b1f424bdf894259e306d6c0626729c 661 Gene3D G3DSA:3.90.550.10 83 338 9.2E-35 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases ALX04_RS02130 64b1f424bdf894259e306d6c0626729c 661 Pfam PF13641 Glycosyltransferase like family 2 84 322 4.0E-17 T 28-03-2018 ALX04_RS02130 64b1f424bdf894259e306d6c0626729c 661 SUPERFAMILY SSF53448 85 372 1.03E-33 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases ALX04_RS02130 64b1f424bdf894259e306d6c0626729c 661 Pfam PF07238 PilZ domain 518 618 3.7E-9 T 28-03-2018 IPR009875 PilZ domain GO:0035438 ALX04_RS14095 491b1766075af115e93e29eb9b454b35 148 Pfam PF10263 SprT-like family 7 98 4.7E-13 T 28-03-2018 IPR006640 SprT-like ALX04_RS14095 491b1766075af115e93e29eb9b454b35 148 Hamap MF_00745 Protein SprT-like. 4 148 39.932 T 28-03-2018 IPR023524 Uncharacterised protein family SprT-like ALX04_RS14095 491b1766075af115e93e29eb9b454b35 148 SMART SM00731 4 148 6.8E-52 T 28-03-2018 IPR006640 SprT-like ALX04_RS12265 a4f32b484b6bf7d60033b942805fb9f0 170 Pfam PF12822 ECF transporter, substrate-specific component 10 156 2.4E-8 T 28-03-2018 IPR024529 ECF transporter, substrate-specific component GO:0005215 ALX04_RS12265 a4f32b484b6bf7d60033b942805fb9f0 170 TIGRFAM TIGR04518 ECF_S_folT_fam: ECF transporter S component, folate family 5 158 2.7E-29 T 28-03-2018 IPR030949 ECF transporter S component, folate family ALX04_RS03865 f241688db09244436ab8357ef8295375 163 PRINTS PR00070 Dihydrofolate reductase signature 27 35 1.4E-11 T 28-03-2018 IPR012259 Dihydrofolate reductase GO:0004146|GO:0006545|GO:0009165|GO:0050661|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-196757 ALX04_RS03865 f241688db09244436ab8357ef8295375 163 PRINTS PR00070 Dihydrofolate reductase signature 40 51 1.4E-11 T 28-03-2018 IPR012259 Dihydrofolate reductase GO:0004146|GO:0006545|GO:0009165|GO:0050661|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-196757 ALX04_RS03865 f241688db09244436ab8357ef8295375 163 PRINTS PR00070 Dihydrofolate reductase signature 94 108 1.4E-11 T 28-03-2018 IPR012259 Dihydrofolate reductase GO:0004146|GO:0006545|GO:0009165|GO:0050661|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-196757 ALX04_RS03865 f241688db09244436ab8357ef8295375 163 PRINTS PR00070 Dihydrofolate reductase signature 13 23 1.4E-11 T 28-03-2018 IPR012259 Dihydrofolate reductase GO:0004146|GO:0006545|GO:0009165|GO:0050661|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-196757 ALX04_RS03865 f241688db09244436ab8357ef8295375 163 SUPERFAMILY SSF53597 1 163 1.11E-53 T 28-03-2018 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 ALX04_RS03865 f241688db09244436ab8357ef8295375 163 Gene3D G3DSA:3.40.430.10 1 163 2.0E-47 T 28-03-2018 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 ALX04_RS03865 f241688db09244436ab8357ef8295375 163 PIRSF PIRSF000194 1 163 9.4E-56 T 28-03-2018 IPR012259 Dihydrofolate reductase GO:0004146|GO:0006545|GO:0009165|GO:0050661|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-196757 ALX04_RS03865 f241688db09244436ab8357ef8295375 163 Pfam PF00186 Dihydrofolate reductase 1 162 1.4E-57 T 28-03-2018 IPR001796 Dihydrofolate reductase domain GO:0004146|GO:0006545|GO:0009165|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-196757 ALX04_RS03865 f241688db09244436ab8357ef8295375 163 ProSitePatterns PS00075 Dihydrofolate reductase (DHFR) domain signature. 13 35 - T 28-03-2018 IPR017925 Dihydrofolate reductase conserved site GO:0004146|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-1474151|Reactome: R-HSA-196757|Reactome: R-HSA-539107 ALX04_RS01645 f7ca846b0864109d32f548499ad54295 216 SMART SM00014 91 201 2.0E-8 T 28-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase ALX04_RS01645 f7ca846b0864109d32f548499ad54295 216 Gene3D G3DSA:1.20.144.10 3 210 4.7E-23 T 28-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase ALX04_RS01645 f7ca846b0864109d32f548499ad54295 216 SUPERFAMILY SSF48317 5 208 7.06E-35 T 28-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase ALX04_RS01645 f7ca846b0864109d32f548499ad54295 216 Pfam PF01569 PAP2 superfamily 94 204 1.2E-14 T 28-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase ALX04_RS14130 33e137d0945727fb3c59b1f7e4735812 310 Pfam PF03613 PTS system mannose/fructose/sorbose family IID component 13 309 4.9E-115 T 28-03-2018 IPR004704 Phosphotransferase system, mannose/fructose/sorbose family IID component GO:0009401|GO:0016021 ALX04_RS05960 c9184ea472118fc175059d632b8ca7fd 163 SUPERFAMILY SSF54631 13 138 7.2E-27 T 28-03-2018 ALX04_RS05960 c9184ea472118fc175059d632b8ca7fd 163 Pfam PF00571 CBS domain 86 136 9.7E-6 T 28-03-2018 IPR000644 CBS domain ALX04_RS05960 c9184ea472118fc175059d632b8ca7fd 163 Gene3D G3DSA:3.10.580.10 1 154 6.1E-16 T 28-03-2018 ALX04_RS09700 2506ee7acfb173fa45d61114aa4e826f 1760 SUPERFAMILY SSF52540 1396 1737 1.8E-23 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase ALX04_RS09700 2506ee7acfb173fa45d61114aa4e826f 1760 Gene3D G3DSA:3.40.50.300 1281 1746 3.3E-15 T 28-03-2018 ALX04_RS09700 2506ee7acfb173fa45d61114aa4e826f 1760 Pfam PF01935 Domain of unknown function DUF87 1398 1619 2.6E-9 T 28-03-2018 IPR002789 Helicase HerA, central domain ALX04_RS02940 7ad8b3fa513007bc9edecae336c7b3ea 478 Pfam PF00425 chorismate binding enzyme 205 457 6.0E-80 T 28-03-2018 IPR015890 Chorismate-utilising enzyme, C-terminal ALX04_RS02940 7ad8b3fa513007bc9edecae336c7b3ea 478 PRINTS PR00095 Anthranilate synthase component I signature 305 318 2.1E-17 T 28-03-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 ALX04_RS02940 7ad8b3fa513007bc9edecae336c7b3ea 478 PRINTS PR00095 Anthranilate synthase component I signature 399 413 2.1E-17 T 28-03-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 ALX04_RS02940 7ad8b3fa513007bc9edecae336c7b3ea 478 PRINTS PR00095 Anthranilate synthase component I signature 319 332 2.1E-17 T 28-03-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 ALX04_RS02940 7ad8b3fa513007bc9edecae336c7b3ea 478 PRINTS PR00095 Anthranilate synthase component I signature 414 428 2.1E-17 T 28-03-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 ALX04_RS02940 7ad8b3fa513007bc9edecae336c7b3ea 478 SUPERFAMILY SSF56322 15 466 2.75E-116 T 28-03-2018 IPR005801 ADC synthase GO:0009058 ALX04_RS02940 7ad8b3fa513007bc9edecae336c7b3ea 478 Pfam PF04715 Anthranilate synthase component I, N terminal region 53 151 1.4E-14 T 28-03-2018 IPR006805 Anthranilate synthase component I, N-terminal GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 ALX04_RS02940 7ad8b3fa513007bc9edecae336c7b3ea 478 Gene3D G3DSA:3.60.120.10 32 474 6.1E-125 T 28-03-2018 IPR005801 ADC synthase GO:0009058 ALX04_RS13010 912e20b7992c0c6d852cc5490975d4ac 337 Pfam PF13346 ABC-2 family transporter protein 59 187 2.5E-6 T 28-03-2018 IPR025699 ABC-2 membrane transporter-like ALX04_RS11565 36030d70d0844bc23764759341c8d616 44 TIGRFAM TIGR01030 rpmH_bact: ribosomal protein bL34 1 44 4.6E-19 T 28-03-2018 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 ALX04_RS11565 36030d70d0844bc23764759341c8d616 44 ProDom PD003101 RIBOSOMAL L34 RIBONUCLEOPROTEIN 50S CHLOROPLAST PLASTID L34 MITOCHONDRIAL PEPTIDE SEQUENCING 2 42 3.0E-13 T 28-03-2018 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 ALX04_RS11565 36030d70d0844bc23764759341c8d616 44 Hamap MF_00391 50S ribosomal protein L34 [rpmH]. 1 44 15.222 T 28-03-2018 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 ALX04_RS11565 36030d70d0844bc23764759341c8d616 44 ProSitePatterns PS00784 Ribosomal protein L34 signature. 2 21 - T 28-03-2018 IPR020939 Ribosomal protein L34, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 ALX04_RS11565 36030d70d0844bc23764759341c8d616 44 Pfam PF00468 Ribosomal protein L34 1 44 1.0E-22 T 28-03-2018 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 ALX04_RS05325 7dc29339f8aa2782e8b7631f5b5f86d6 310 SUPERFAMILY SSF56327 149 301 6.79E-9 T 28-03-2018 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 ALX04_RS05325 7dc29339f8aa2782e8b7631f5b5f86d6 310 Gene3D G3DSA:3.90.110.10 140 306 1.1E-11 T 28-03-2018 ALX04_RS14640 e4341e7db88dec51da0f1f8f7298843d 150 Pfam PF11694 Protein of unknown function (DUF3290) 2 145 4.6E-48 T 28-03-2018 IPR021707 Protein of unknown function DUF3290 ALX04_RS14640 e4341e7db88dec51da0f1f8f7298843d 150 Gene3D G3DSA:1.10.287.980 2 87 8.7E-4 T 28-03-2018 ALX04_RS02830 a9306570e851b74fd39c7bbbb180b835 219 SMART SM00983 144 207 1.3E-15 T 28-03-2018 IPR007373 Thiamin pyrophosphokinase, vitamin B1-binding domain GO:0009229|GO:0030975 KEGG: 00730+2.7.6.2|MetaCyc: PWY-6898|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|Reactome: R-HSA-196819 ALX04_RS02830 a9306570e851b74fd39c7bbbb180b835 219 Pfam PF04263 Thiamin pyrophosphokinase, catalytic domain 27 119 1.2E-19 T 28-03-2018 IPR007371 Thiamin pyrophosphokinase, catalytic domain GO:0004788|GO:0005524|GO:0009229 KEGG: 00730+2.7.6.2|MetaCyc: PWY-6898|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|Reactome: R-HSA-196819 ALX04_RS02830 a9306570e851b74fd39c7bbbb180b835 219 Gene3D G3DSA:3.40.50.10240 2 117 1.1E-23 T 28-03-2018 IPR007371 Thiamin pyrophosphokinase, catalytic domain GO:0004788|GO:0005524|GO:0009229 KEGG: 00730+2.7.6.2|MetaCyc: PWY-6898|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|Reactome: R-HSA-196819 ALX04_RS02830 a9306570e851b74fd39c7bbbb180b835 219 Gene3D G3DSA:2.60.120.320 118 219 3.3E-7 T 28-03-2018 IPR007373 Thiamin pyrophosphokinase, vitamin B1-binding domain GO:0009229|GO:0030975 KEGG: 00730+2.7.6.2|MetaCyc: PWY-6898|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|Reactome: R-HSA-196819 ALX04_RS02830 a9306570e851b74fd39c7bbbb180b835 219 TIGRFAM TIGR01378 thi_PPkinase: thiamine pyrophosphokinase 6 209 1.2E-60 T 28-03-2018 IPR006282 Thiamin pyrophosphokinase GO:0004788|GO:0006772 KEGG: 00730+2.7.6.2|MetaCyc: PWY-6898|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|Reactome: R-HSA-196819 ALX04_RS02830 a9306570e851b74fd39c7bbbb180b835 219 SUPERFAMILY SSF63999 3 133 1.44E-35 T 28-03-2018 IPR007371 Thiamin pyrophosphokinase, catalytic domain GO:0004788|GO:0005524|GO:0009229 KEGG: 00730+2.7.6.2|MetaCyc: PWY-6898|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|Reactome: R-HSA-196819 ALX04_RS04620 6b1b974dfeb575646e70f2e7a781caee 425 SMART SM00228 192 262 1.9E-4 T 28-03-2018 IPR001478 PDZ domain GO:0005515 ALX04_RS04620 6b1b974dfeb575646e70f2e7a781caee 425 SUPERFAMILY SSF50156 176 271 7.62E-17 T 28-03-2018 IPR001478 PDZ domain GO:0005515 ALX04_RS04620 6b1b974dfeb575646e70f2e7a781caee 425 Pfam PF02163 Peptidase family M50 7 411 2.8E-78 T 28-03-2018 IPR008915 Peptidase M50 GO:0004222|GO:0006508 Reactome: R-HSA-1655829|Reactome: R-HSA-381033|Reactome: R-HSA-8874211|Reactome: R-HSA-8963889|Reactome: R-MMU-8963889 ALX04_RS04620 6b1b974dfeb575646e70f2e7a781caee 425 Pfam PF13180 PDZ domain 207 270 2.9E-9 T 28-03-2018 IPR001478 PDZ domain GO:0005515 ALX04_RS04620 6b1b974dfeb575646e70f2e7a781caee 425 Gene3D G3DSA:2.30.42.10 201 291 1.8E-18 T 28-03-2018 ALX04_RS04620 6b1b974dfeb575646e70f2e7a781caee 425 TIGRFAM TIGR00054 TIGR00054: RIP metalloprotease RseP 3 424 1.1E-88 T 28-03-2018 IPR004387 Peptidase M50, putative membrane-associated zinc metallopeptidase GO:0004222|GO:0006508|GO:0016021 ALX04_RS09880 0c6dd88537344df46ff061a82852c2d8 241 Pfam PF06570 Protein of unknown function (DUF1129) 32 238 1.1E-64 T 28-03-2018 IPR009214 Protein of unknown function DUF1129 ALX04_RS09880 0c6dd88537344df46ff061a82852c2d8 241 Gene3D G3DSA:1.10.1900.10 20 95 4.4E-5 T 28-03-2018 ALX04_RS09880 0c6dd88537344df46ff061a82852c2d8 241 PIRSF PIRSF033111 17 241 7.2E-46 T 28-03-2018 IPR009214 Protein of unknown function DUF1129 ALX04_RS08400 665b63212beffb33128eed5a8cd7edfc 395 Pfam PF07690 Major Facilitator Superfamily 15 252 3.4E-22 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 ALX04_RS08400 665b63212beffb33128eed5a8cd7edfc 395 SUPERFAMILY SSF103473 7 391 6.93E-56 T 28-03-2018 IPR020846 Major facilitator superfamily domain ALX04_RS08400 665b63212beffb33128eed5a8cd7edfc 395 Gene3D G3DSA:1.20.1250.20 2 197 5.0E-20 T 28-03-2018 ALX04_RS08400 665b63212beffb33128eed5a8cd7edfc 395 Gene3D G3DSA:1.20.1250.20 198 392 5.4E-24 T 28-03-2018 ALX04_RS10255 3c24d37a3f0d86780f9f18906fb90bb9 372 SUPERFAMILY SSF51726 13 370 2.09E-78 T 28-03-2018 ALX04_RS10255 3c24d37a3f0d86780f9f18906fb90bb9 372 Pfam PF01717 Cobalamin-independent synthase, Catalytic domain 14 345 9.9E-17 T 28-03-2018 IPR002629 Cobalamin-independent methionine synthase MetE, C-terminal/archaeal GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 ALX04_RS10255 3c24d37a3f0d86780f9f18906fb90bb9 372 Gene3D G3DSA:3.20.20.210 4 372 3.1E-90 T 28-03-2018 ALX04_RS11950 5d6824cc873527d466224e9496b093af 144 Gene3D G3DSA:2.30.110.10 1 144 1.8E-7 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 ALX04_RS11950 5d6824cc873527d466224e9496b093af 144 SUPERFAMILY SSF50475 1 72 1.73E-5 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 ALX04_RS14790 aefc85307dae6811afa21a40f36c3ffe 249 Gene3D G3DSA:3.40.50.1820 1 249 3.8E-31 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold ALX04_RS14790 aefc85307dae6811afa21a40f36c3ffe 249 PIRSF PIRSF017388 1 249 2.5E-75 T 28-03-2018 IPR012354 Esterase/lipase GO:0052689 ALX04_RS14790 aefc85307dae6811afa21a40f36c3ffe 249 Pfam PF12146 Serine aminopeptidase, S33 15 227 9.5E-18 T 28-03-2018 IPR022742 Serine aminopeptidase, S33 ALX04_RS14790 aefc85307dae6811afa21a40f36c3ffe 249 SUPERFAMILY SSF53474 15 247 1.33E-32 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold ALX04_RS10805 cd0eb46953a3be07908c8681113f0c18 317 Pfam PF04261 Dyp-type peroxidase family 11 307 8.6E-67 T 28-03-2018 IPR006314 Dyp-type peroxidase GO:0004601|GO:0020037|GO:0055114 ALX04_RS10805 cd0eb46953a3be07908c8681113f0c18 317 SUPERFAMILY SSF54909 8 312 3.93E-87 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel ALX04_RS10805 cd0eb46953a3be07908c8681113f0c18 317 TIGRFAM TIGR01413 Dyp_perox_fam: Dyp-type peroxidase family 13 306 1.5E-59 T 28-03-2018 IPR006314 Dyp-type peroxidase GO:0004601|GO:0020037|GO:0055114 ALX04_RS06945 9a31a620b9ae28b67dce1a9a61794bf2 266 Pfam PF08708 Primase C terminal 1 (PriCT-1) 200 262 3.3E-12 T 28-03-2018 IPR014820 Primase, C-terminal 1 ALX04_RS06945 9a31a620b9ae28b67dce1a9a61794bf2 266 SMART SM00942 198 263 4.0E-22 T 28-03-2018 IPR014820 Primase, C-terminal 1 ALX04_RS06945 9a31a620b9ae28b67dce1a9a61794bf2 266 SUPERFAMILY SSF56747 7 173 7.19E-23 T 28-03-2018 ALX04_RS06945 9a31a620b9ae28b67dce1a9a61794bf2 266 SMART SM00943 10 167 3.0E-44 T 28-03-2018 IPR015330 DNA primase/polymerase, bifunctional, N-terminal ALX04_RS06945 9a31a620b9ae28b67dce1a9a61794bf2 266 Pfam PF09250 Bifunctional DNA primase/polymerase, N-terminal 10 166 5.1E-27 T 28-03-2018 IPR015330 DNA primase/polymerase, bifunctional, N-terminal ALX04_RS15475 677c930f730b883fe466aec4c00cb157 16 TIGRFAM TIGR03715 KxYKxGKxW: KxYKxGKxW signal peptide 1 16 1.5E-7 T 28-03-2018 IPR022263 KxYKxGKxW signal peptide ALX04_RS12255 e00a385dd3c7beb239a3477312095d8d 220 Gene3D G3DSA:1.10.357.10 65 213 6.0E-15 T 28-03-2018 ALX04_RS12255 e00a385dd3c7beb239a3477312095d8d 220 Gene3D G3DSA:1.10.10.60 4 64 5.5E-12 T 28-03-2018 ALX04_RS12255 e00a385dd3c7beb239a3477312095d8d 220 SUPERFAMILY SSF48498 84 212 3.34E-26 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal ALX04_RS12255 e00a385dd3c7beb239a3477312095d8d 220 SUPERFAMILY SSF46689 7 83 1.64E-15 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 ALX04_RS12255 e00a385dd3c7beb239a3477312095d8d 220 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 38 61 1.1E-6 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 ALX04_RS12255 e00a385dd3c7beb239a3477312095d8d 220 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 17 30 1.1E-6 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 ALX04_RS12255 e00a385dd3c7beb239a3477312095d8d 220 Pfam PF00440 Bacterial regulatory proteins, tetR family 17 62 1.7E-10 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 ALX04_RS12080 c55d53caa1cbb2f56f2bcbc12506d017 260 Pfam PF12697 Alpha/beta hydrolase family 22 249 5.3E-13 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 ALX04_RS12080 c55d53caa1cbb2f56f2bcbc12506d017 260 Gene3D G3DSA:3.40.50.1820 1 260 7.7E-35 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold ALX04_RS12080 c55d53caa1cbb2f56f2bcbc12506d017 260 SUPERFAMILY SSF53474 1 258 3.37E-47 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold ALX04_RS14720 bcc7f67af68e57136609fe77357ee84b 550 Gene3D G3DSA:3.90.76.10 67 197 1.8E-36 T 28-03-2018 ALX04_RS14720 bcc7f67af68e57136609fe77357ee84b 550 Gene3D G3DSA:3.40.190.10 200 301 2.1E-15 T 28-03-2018 ALX04_RS14720 bcc7f67af68e57136609fe77357ee84b 550 Gene3D G3DSA:3.10.105.10 302 520 5.5E-45 T 28-03-2018 ALX04_RS14720 bcc7f67af68e57136609fe77357ee84b 550 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 79 469 8.1E-70 T 28-03-2018 IPR000914 Solute-binding protein family 5 domain ALX04_RS14720 bcc7f67af68e57136609fe77357ee84b 550 SUPERFAMILY SSF53850 39 548 8.22E-112 T 28-03-2018 ALX04_RS14720 bcc7f67af68e57136609fe77357ee84b 550 PIRSF PIRSF002741 1 550 5.1E-87 T 28-03-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 ALX04_RS01615 07adebc32d83cac696cad7226e5f1ab5 544 SUPERFAMILY SSF48208 222 403 4.76E-8 T 28-03-2018 IPR008928 Six-hairpin glycosidase-like GO:0003824 ALX04_RS01615 07adebc32d83cac696cad7226e5f1ab5 544 Gene3D G3DSA:1.50.10.10 196 494 3.6E-14 T 28-03-2018 ALX04_RS00110 24f63233496863e4883adc9eb037ae6d 254 PIRSF PIRSF031503 1 254 2.1E-111 T 28-03-2018 IPR014564 Uncharacterised conserved protein UCP031503, transmembrane ALX04_RS00110 24f63233496863e4883adc9eb037ae6d 254 Pfam PF07907 YibE/F-like protein 4 243 5.1E-59 T 28-03-2018 IPR012507 YibE/F-like ALX04_RS03800 ad43ce6f699d8954e7b209164355484b 255 SUPERFAMILY SSF53098 61 252 1.67E-67 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 ALX04_RS03800 ad43ce6f699d8954e7b209164355484b 255 Gene3D G3DSA:3.30.420.10 47 254 3.0E-68 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 ALX04_RS03800 ad43ce6f699d8954e7b209164355484b 255 Pfam PF01351 Ribonuclease HII 73 248 5.8E-38 T 28-03-2018 IPR024567 Ribonuclease HII/HIII domain ALX04_RS03800 ad43ce6f699d8954e7b209164355484b 255 Hamap MF_00052_B Ribonuclease HII [rnhB]. 71 249 35.107 T 28-03-2018 IPR022898 Ribonuclease HII GO:0004523 ALX04_RS14885 e879925a3759efab0e32d30204cb8af1 280 Hamap MF_01499 Diadenylate cyclase [dacA]. 9 255 32.259 T 28-03-2018 IPR034701 Diadenylate cyclase CdaA GO:0004016|GO:0006171 ALX04_RS14885 e879925a3759efab0e32d30204cb8af1 280 Pfam PF02457 DisA bacterial checkpoint controller nucleotide-binding 119 236 1.7E-42 T 28-03-2018 IPR003390 DNA integrity scanning protein, DisA, N-terminal ALX04_RS14885 e879925a3759efab0e32d30204cb8af1 280 PIRSF PIRSF004793 6 270 2.1E-86 T 28-03-2018 IPR014046 Diadenylate cyclase GO:0004016|GO:0006171 ALX04_RS14885 e879925a3759efab0e32d30204cb8af1 280 TIGRFAM TIGR00159 TIGR00159: TIGR00159 family protein 10 246 5.6E-87 T 28-03-2018 IPR034701 Diadenylate cyclase CdaA GO:0004016|GO:0006171 ALX04_RS14885 e879925a3759efab0e32d30204cb8af1 280 SUPERFAMILY SSF143597 42 240 3.27E-69 T 28-03-2018 IPR003390 DNA integrity scanning protein, DisA, N-terminal ALX04_RS14885 e879925a3759efab0e32d30204cb8af1 280 Gene3D G3DSA:3.40.1700.10 112 239 1.1E-35 T 28-03-2018 IPR003390 DNA integrity scanning protein, DisA, N-terminal ALX04_RS00690 b946d1285cb53c2ff72443a05c0f9e76 96 ProDom PD015389 LYASE CITRATE ACYL CARRIER GAMMA CHAIN CITD PRECURSOR SIGNAL DIRECT 10 77 6.0E-33 T 28-03-2018 IPR006495 Citrate lyase acyl carrier protein CitD GO:0005737 ALX04_RS00690 b946d1285cb53c2ff72443a05c0f9e76 96 PIRSF PIRSF002736 1 96 8.1E-41 T 28-03-2018 IPR006495 Citrate lyase acyl carrier protein CitD GO:0005737 ALX04_RS00690 b946d1285cb53c2ff72443a05c0f9e76 96 Pfam PF06857 Malonate decarboxylase delta subunit (MdcD) 5 85 2.9E-30 T 28-03-2018 IPR023439 Malonate decarboxylase/citrate lyase acyl carrier protein ALX04_RS00690 b946d1285cb53c2ff72443a05c0f9e76 96 Hamap MF_00805 Citrate lyase acyl carrier protein [citD]. 1 96 26.29 T 28-03-2018 IPR006495 Citrate lyase acyl carrier protein CitD GO:0005737 ALX04_RS00690 b946d1285cb53c2ff72443a05c0f9e76 96 TIGRFAM TIGR01608 citD: citrate lyase acyl carrier protein 1 93 4.6E-36 T 28-03-2018 IPR006495 Citrate lyase acyl carrier protein CitD GO:0005737 ALX04_RS08180 765e3b02ab1f3e575257c04bc560851f 224 SUPERFAMILY SSF53254 1 220 1.91E-48 T 28-03-2018 IPR029033 Histidine phosphatase superfamily ALX04_RS08180 765e3b02ab1f3e575257c04bc560851f 224 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 134 218 2.3E-9 T 28-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 ALX04_RS08180 765e3b02ab1f3e575257c04bc560851f 224 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 6 106 3.5E-28 T 28-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 ALX04_RS08180 765e3b02ab1f3e575257c04bc560851f 224 PIRSF PIRSF000709 2 104 1.0E-6 T 28-03-2018 ALX04_RS08180 765e3b02ab1f3e575257c04bc560851f 224 PIRSF PIRSF000709 164 193 39.0 T 28-03-2018 ALX04_RS08180 765e3b02ab1f3e575257c04bc560851f 224 SMART SM00855 5 182 6.9E-19 T 28-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 ALX04_RS08180 765e3b02ab1f3e575257c04bc560851f 224 Gene3D G3DSA:3.40.50.1240 1 220 1.2E-43 T 28-03-2018 IPR029033 Histidine phosphatase superfamily ALX04_RS08180 765e3b02ab1f3e575257c04bc560851f 224 ProSitePatterns PS00175 Phosphoglycerate mutase family phosphohistidine signature. 8 17 - T 28-03-2018 IPR001345 Phosphoglycerate/bisphosphoglycerate mutase, active site GO:0003824|GO:0008152 ALX04_RS11290 2ffe0835fa8e2fec651325a84e7b4dd7 132 SUPERFAMILY SSF160515 7 131 9.02E-37 T 28-03-2018 ALX04_RS11290 2ffe0835fa8e2fec651325a84e7b4dd7 132 Gene3D G3DSA:3.30.1330.30 6 128 1.2E-33 T 28-03-2018 IPR029064 50S ribosomal protein L30e-like ALX04_RS11290 2ffe0835fa8e2fec651325a84e7b4dd7 132 Pfam PF07997 Protein of unknown function (DUF1694) 7 124 4.4E-35 T 28-03-2018 IPR012543 Protein of unknown function DUF1694 ALX04_RS11290 2ffe0835fa8e2fec651325a84e7b4dd7 132 PIRSF PIRSF034303 3 132 2.2E-52 T 28-03-2018 IPR012543 Protein of unknown function DUF1694 ALX04_RS02840 4eeac44e0ac8665cfe9f768158f9aaa9 120 Pfam PF03780 Asp23 family, cell envelope-related function 10 116 6.0E-34 T 28-03-2018 IPR005531 Alkaline shock protein Asp23 ALX04_RS02050 57c252f94c2399bf4ccaeb63e0f117f0 315 Gene3D G3DSA:3.40.190.10 198 275 4.4E-17 T 28-03-2018 ALX04_RS02050 57c252f94c2399bf4ccaeb63e0f117f0 315 Pfam PF03466 LysR substrate binding domain 93 302 1.3E-33 T 28-03-2018 IPR005119 LysR, substrate-binding ALX04_RS02050 57c252f94c2399bf4ccaeb63e0f117f0 315 Gene3D G3DSA:1.10.10.10 4 96 4.6E-14 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS02050 57c252f94c2399bf4ccaeb63e0f117f0 315 SUPERFAMILY SSF53850 94 305 8.57E-33 T 28-03-2018 ALX04_RS02050 57c252f94c2399bf4ccaeb63e0f117f0 315 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 11 66 7.9E-15 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 ALX04_RS02050 57c252f94c2399bf4ccaeb63e0f117f0 315 Gene3D G3DSA:3.40.190.10 97 197 1.9E-13 T 28-03-2018 ALX04_RS02050 57c252f94c2399bf4ccaeb63e0f117f0 315 SUPERFAMILY SSF46785 10 114 9.33E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS02050 57c252f94c2399bf4ccaeb63e0f117f0 315 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 22 33 1.8E-6 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 ALX04_RS02050 57c252f94c2399bf4ccaeb63e0f117f0 315 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 43 54 1.8E-6 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 ALX04_RS02050 57c252f94c2399bf4ccaeb63e0f117f0 315 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 33 43 1.8E-6 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 ALX04_RS00260 119cde2652c5047426bf5eab89c7b024 181 SUPERFAMILY SSF55729 4 160 6.1E-30 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase ALX04_RS00260 119cde2652c5047426bf5eab89c7b024 181 Gene3D G3DSA:3.40.630.30 4 178 3.6E-20 T 28-03-2018 ALX04_RS00260 119cde2652c5047426bf5eab89c7b024 181 Pfam PF13302 Acetyltransferase (GNAT) domain 13 152 3.8E-25 T 28-03-2018 IPR000182 GNAT domain GO:0008080 ALX04_RS14415 8e55e7a537e9b221904a758b05866bce 331 TIGRFAM TIGR01179 galE: UDP-glucose 4-epimerase GalE 3 326 7.5E-133 T 28-03-2018 IPR005886 UDP-glucose 4-epimerase GO:0003978|GO:0006012 KEGG: 00052+5.1.3.2|KEGG: 00520+5.1.3.2|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6397|MetaCyc: PWY-6527|MetaCyc: PWY-7328|MetaCyc: PWY-7344|Reactome: R-HSA-70370 ALX04_RS14415 8e55e7a537e9b221904a758b05866bce 331 Gene3D G3DSA:3.90.25.10 312 328 0.031 T 28-03-2018 ALX04_RS14415 8e55e7a537e9b221904a758b05866bce 331 Gene3D G3DSA:3.90.25.10 227 311 3.3E-21 T 28-03-2018 ALX04_RS14415 8e55e7a537e9b221904a758b05866bce 331 SUPERFAMILY SSF51735 1 327 2.56E-98 T 28-03-2018 IPR016040 NAD(P)-binding domain ALX04_RS14415 8e55e7a537e9b221904a758b05866bce 331 Gene3D G3DSA:3.40.50.720 2 226 1.2E-48 T 28-03-2018 ALX04_RS14415 8e55e7a537e9b221904a758b05866bce 331 Pfam PF01370 NAD dependent epimerase/dehydratase family 3 252 8.8E-62 T 28-03-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 ALX04_RS06210 c919458706bd7973ae3d678959ff10c1 412 Pfam PF04262 Glutamate-cysteine ligase 248 317 7.5E-10 T 28-03-2018 IPR007370 Glutamate--cysteine ligase GO:0004357|GO:0006750 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 ALX04_RS06210 c919458706bd7973ae3d678959ff10c1 412 Pfam PF04262 Glutamate-cysteine ligase 16 244 5.5E-49 T 28-03-2018 IPR007370 Glutamate--cysteine ligase GO:0004357|GO:0006750 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 ALX04_RS06210 c919458706bd7973ae3d678959ff10c1 412 SUPERFAMILY SSF55931 2 405 2.16E-105 T 28-03-2018 ALX04_RS11125 c9040d485199588f2b15203cd3dfc02b 263 Gene3D G3DSA:3.40.50.1820 1 257 1.1E-33 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold ALX04_RS11125 c9040d485199588f2b15203cd3dfc02b 263 SUPERFAMILY SSF53474 3 256 3.32E-47 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold ALX04_RS11125 c9040d485199588f2b15203cd3dfc02b 263 Pfam PF00756 Putative esterase 33 251 1.3E-23 T 28-03-2018 IPR000801 Putative esterase Reactome: R-HSA-156590 ALX04_RS14150 e16011ce4f0b7c6548fff4426484e345 172 Pfam PF03830 PTS system sorbose subfamily IIB component 5 153 7.0E-44 T 28-03-2018 IPR004720 Phosphotransferase system, sorbose subfamily IIB component GO:0005737|GO:0008982|GO:0009401 ALX04_RS14150 e16011ce4f0b7c6548fff4426484e345 172 Gene3D G3DSA:3.40.35.10 4 162 1.3E-46 T 28-03-2018 IPR004720 Phosphotransferase system, sorbose subfamily IIB component GO:0005737|GO:0008982|GO:0009401 ALX04_RS14150 e16011ce4f0b7c6548fff4426484e345 172 SUPERFAMILY SSF52728 3 165 1.96E-47 T 28-03-2018 IPR004720 Phosphotransferase system, sorbose subfamily IIB component GO:0005737|GO:0008982|GO:0009401 ALX04_RS11765 3c3ba9556d2e2b9cf6a78a3591191926 210 SUPERFAMILY SSF52141 21 207 1.73E-45 T 28-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 ALX04_RS11765 3c3ba9556d2e2b9cf6a78a3591191926 210 Gene3D G3DSA:3.40.470.10 16 210 9.7E-37 T 28-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 ALX04_RS11765 3c3ba9556d2e2b9cf6a78a3591191926 210 SMART SM00986 46 202 5.7E-20 T 28-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 ALX04_RS11765 3c3ba9556d2e2b9cf6a78a3591191926 210 SMART SM00987 46 202 5.7E-20 T 28-03-2018 ALX04_RS11765 3c3ba9556d2e2b9cf6a78a3591191926 210 Pfam PF03167 Uracil DNA glycosylase superfamily 50 202 1.1E-19 T 28-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 ALX04_RS12110 962f648af244ce833fe85dd2dda674f3 252 Pfam PF01048 Phosphorylase superfamily 64 224 1.7E-23 T 28-03-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 ALX04_RS12110 962f648af244ce833fe85dd2dda674f3 252 Gene3D G3DSA:3.40.50.1580 35 248 9.6E-20 T 28-03-2018 ALX04_RS12110 962f648af244ce833fe85dd2dda674f3 252 SUPERFAMILY SSF53167 35 249 1.18E-45 T 28-03-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 ALX04_RS04120 44513f71f06cdd333361d117e083b02b 133 Gene3D G3DSA:3.40.30.10 1 128 1.2E-29 T 28-03-2018 ALX04_RS04120 44513f71f06cdd333361d117e083b02b 133 TIGRFAM TIGR01617 arsC_related: transcriptional regulator, Spx/MgsR family 2 114 2.6E-29 T 28-03-2018 IPR006504 Transcriptional regulator Spx/MgsR ALX04_RS04120 44513f71f06cdd333361d117e083b02b 133 SUPERFAMILY SSF52833 1 125 2.92E-30 T 28-03-2018 IPR012336 Thioredoxin-like fold ALX04_RS04120 44513f71f06cdd333361d117e083b02b 133 Pfam PF03960 ArsC family 38 113 1.3E-14 T 28-03-2018 IPR006660 Arsenate reductase-like ALX04_RS04530 7493a1b9537a9a13903cbe11862202f9 347 SUPERFAMILY SSF55781 73 342 7.06E-64 T 28-03-2018 IPR029016 GAF domain-like ALX04_RS04530 7493a1b9537a9a13903cbe11862202f9 347 Pfam PF03444 Winged helix-turn-helix transcription repressor, HrcA DNA-binding 4 73 1.3E-4 T 28-03-2018 IPR005104 Winged helix-turn-helix transcription repressor, HrcA DNA-binding domain GO:0003677|GO:0006355 ALX04_RS04530 7493a1b9537a9a13903cbe11862202f9 347 Gene3D G3DSA:3.30.390.60 130 204 5.7E-17 T 28-03-2018 IPR023120 Winged helix-turn-helix transcription repressor, HrcA, inserted dimerising domain ALX04_RS04530 7493a1b9537a9a13903cbe11862202f9 347 Gene3D G3DSA:1.10.10.10 1 87 4.9E-30 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS04530 7493a1b9537a9a13903cbe11862202f9 347 Hamap MF_00081 Heat-inducible transcription repressor HrcA [hrcA]. 3 331 28.988 T 28-03-2018 IPR002571 Heat-inducible transcription repressor HrcA GO:0003677|GO:0006355 ALX04_RS04530 7493a1b9537a9a13903cbe11862202f9 347 SUPERFAMILY SSF46785 4 86 3.18E-24 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS04530 7493a1b9537a9a13903cbe11862202f9 347 TIGRFAM TIGR00331 hrcA: heat-inducible transcription repressor HrcA 5 337 2.9E-94 T 28-03-2018 IPR002571 Heat-inducible transcription repressor HrcA GO:0003677|GO:0006355 ALX04_RS04530 7493a1b9537a9a13903cbe11862202f9 347 Gene3D G3DSA:3.30.450.40 205 344 1.1E-31 T 28-03-2018 IPR029016 GAF domain-like ALX04_RS04530 7493a1b9537a9a13903cbe11862202f9 347 Pfam PF01628 HrcA protein C terminal domain 106 324 1.8E-48 T 28-03-2018 IPR021153 Heat-inducible transcription repressor HrcA, C-terminal GO:0003677|GO:0006355 ALX04_RS04530 7493a1b9537a9a13903cbe11862202f9 347 PIRSF PIRSF005485 1 342 3.7E-96 T 28-03-2018 IPR002571 Heat-inducible transcription repressor HrcA GO:0003677|GO:0006355 ALX04_RS01985 a93a59f24c014442c0a13b1281c1c0fc 80 SUPERFAMILY SSF47336 3 79 1.96E-15 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain ALX04_RS01985 a93a59f24c014442c0a13b1281c1c0fc 80 Pfam PF00550 Phosphopantetheine attachment site 9 74 4.0E-12 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain ALX04_RS01985 a93a59f24c014442c0a13b1281c1c0fc 80 Gene3D G3DSA:1.10.1200.10 4 80 6.4E-14 T 28-03-2018 ALX04_RS01985 a93a59f24c014442c0a13b1281c1c0fc 80 Hamap MF_00565 D-alanine--poly(phosphoribitol) ligase subunit 2 [dltC]. 1 80 45.251 T 28-03-2018 IPR003230 D-alanine--poly(phosphoribitol) ligase subunit 2 GO:0019350|GO:0036370 KEGG: 00473+6.1.1.13 ALX04_RS01985 a93a59f24c014442c0a13b1281c1c0fc 80 TIGRFAM TIGR01688 dltC: D-alanine--poly(phosphoribitol) ligase, subunit 2 7 76 2.0E-29 T 28-03-2018 IPR003230 D-alanine--poly(phosphoribitol) ligase subunit 2 GO:0019350|GO:0036370 KEGG: 00473+6.1.1.13 ALX04_RS03725 e65e9a679dc0366302951e551a2da664 66 SUPERFAMILY SSF140652 1 65 9.55E-10 T 28-03-2018 IPR023089 YozE SAM-like domain ALX04_RS03725 e65e9a679dc0366302951e551a2da664 66 Gene3D G3DSA:1.10.150.260 1 66 5.8E-11 T 28-03-2018 IPR023089 YozE SAM-like domain ALX04_RS03725 e65e9a679dc0366302951e551a2da664 66 Pfam PF06855 YozE SAM-like fold 2 64 2.2E-13 T 28-03-2018 IPR023089 YozE SAM-like domain ALX04_RS09385 2d4006c36528d4413725d081af8dbb55 494 Pfam PF13520 Amino acid permease 10 476 7.7E-31 T 28-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 ALX04_RS09385 2d4006c36528d4413725d081af8dbb55 494 PIRSF PIRSF006060 1 494 1.9E-54 T 28-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 ALX04_RS04400 5673796c11b75fe9373466db5fc22d12 386 Pfam PF04464 CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase 96 374 1.9E-46 T 28-03-2018 IPR007554 CDP-glycerol glycerophosphotransferase GO:0016020|GO:0047355 ALX04_RS15210 1ccc5b0ce4980a0ceead3c45cae04f82 385 SUPERFAMILY SSF103473 12 383 1.31E-51 T 28-03-2018 IPR020846 Major facilitator superfamily domain ALX04_RS15210 1ccc5b0ce4980a0ceead3c45cae04f82 385 Pfam PF07690 Major Facilitator Superfamily 15 288 3.5E-30 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 ALX04_RS15210 1ccc5b0ce4980a0ceead3c45cae04f82 385 Gene3D G3DSA:1.20.1250.20 3 186 1.4E-29 T 28-03-2018 ALX04_RS15210 1ccc5b0ce4980a0ceead3c45cae04f82 385 Gene3D G3DSA:1.20.1250.20 199 383 9.2E-14 T 28-03-2018 ALX04_RS05465 6f4b5a8a47983ba7b8f71fb119e6a0a0 134 Pfam PF11457 Protein of unknown function (DUF3021) 1 121 5.7E-16 T 28-03-2018 IPR021560 Protein of unknown function DUF3021 ALX04_RS12055 8cf7d074eb935aa529be8b8861c07ca1 246 SUPERFAMILY SSF52317 28 245 1.45E-40 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like ALX04_RS12055 8cf7d074eb935aa529be8b8861c07ca1 246 Gene3D G3DSA:3.40.50.880 1 246 1.8E-42 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like ALX04_RS12055 8cf7d074eb935aa529be8b8861c07ca1 246 Pfam PF07722 Peptidase C26 4 224 2.8E-68 T 28-03-2018 IPR011697 Peptidase C26 GO:0016787 Reactome: R-HSA-6798695 ALX04_RS14635 3cb38838c4eda7cdf1ae068f74242f39 210 Pfam PF04239 Protein of unknown function (DUF421) 88 189 1.7E-30 T 28-03-2018 IPR007353 Protein of unknown function DUF421 ALX04_RS14635 3cb38838c4eda7cdf1ae068f74242f39 210 Gene3D G3DSA:3.30.240.20 156 209 1.2E-10 T 28-03-2018 IPR023090 Uncharacterised domain UPF0702, alpha/beta domain ALX04_RS14635 3cb38838c4eda7cdf1ae068f74242f39 210 Gene3D G3DSA:3.30.240.20 82 151 3.5E-16 T 28-03-2018 IPR023090 Uncharacterised domain UPF0702, alpha/beta domain ALX04_RS14315 9e0f95218c3e50ddbe1f226bddb446c6 325 Pfam PF13930 DNA/RNA non-specific endonuclease 162 293 3.9E-45 T 28-03-2018 ALX04_RS09830 4d13375666cd38661e68f694de4aebf2 240 Pfam PF01925 Sulfite exporter TauE/SafE 7 234 1.1E-21 T 28-03-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 ALX04_RS04205 c5b33f2623eb77082e97ad5ed5f41be7 284 Gene3D G3DSA:3.40.50.1820 35 282 2.2E-24 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold ALX04_RS04205 c5b33f2623eb77082e97ad5ed5f41be7 284 SUPERFAMILY SSF53474 41 244 1.23E-15 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold ALX04_RS04205 c5b33f2623eb77082e97ad5ed5f41be7 284 Pfam PF06028 Alpha/beta hydrolase of unknown function (DUF915) 35 281 1.3E-76 T 28-03-2018 IPR010315 Protein of unknown function DUF915, hydrolase-like ALX04_RS03740 32fafde39ef20da217cce384be6b8d33 309 SUPERFAMILY SSF64182 3 307 1.27E-79 T 28-03-2018 ALX04_RS03740 32fafde39ef20da217cce384be6b8d33 309 Pfam PF02833 DHHA2 domain 183 306 8.0E-19 T 28-03-2018 IPR004097 DHHA2 domain GO:0005737|GO:0016462 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 ALX04_RS03740 32fafde39ef20da217cce384be6b8d33 309 Gene3D G3DSA:3.90.1640.10 1 188 2.0E-61 T 28-03-2018 ALX04_RS03740 32fafde39ef20da217cce384be6b8d33 309 Pfam PF01368 DHH family 5 146 5.8E-25 T 28-03-2018 IPR001667 DDH domain KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 ALX04_RS03740 32fafde39ef20da217cce384be6b8d33 309 SMART SM01131 181 307 1.5E-59 T 28-03-2018 IPR004097 DHHA2 domain GO:0005737|GO:0016462 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 ALX04_RS03740 32fafde39ef20da217cce384be6b8d33 309 Hamap MF_00207 Probable manganese-dependent inorganic pyrophosphatase [ppaC]. 3 309 42.354 T 28-03-2018 IPR022934 Manganese-dependent inorganic pyrophosphatase, probable GO:0004427 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 ALX04_RS13545 0f2c7198beac8afa3e39a9cb0da0e9d7 83 Gene3D G3DSA:2.30.30.100 3 76 1.5E-30 T 28-03-2018 ALX04_RS13545 0f2c7198beac8afa3e39a9cb0da0e9d7 83 PIRSF PIRSF037257 1 83 9.5E-36 T 28-03-2018 IPR009366 Protein Veg GO:0042710 ALX04_RS13545 0f2c7198beac8afa3e39a9cb0da0e9d7 83 Pfam PF06257 Biofilm formation stimulator VEG 4 74 5.6E-30 T 28-03-2018 IPR009366 Protein Veg GO:0042710 ALX04_RS10490 3ba62795bdac01337f631a188e6630b5 166 SUPERFAMILY SSF101307 11 165 3.92E-46 T 28-03-2018 IPR007686 YutG/PgpA domain GO:0006629|GO:0008962 ALX04_RS10490 3ba62795bdac01337f631a188e6630b5 166 Pfam PF04608 Phosphatidylglycerophosphatase A 26 162 1.0E-13 T 28-03-2018 IPR007686 YutG/PgpA domain GO:0006629|GO:0008962 ALX04_RS10490 3ba62795bdac01337f631a188e6630b5 166 Gene3D G3DSA:1.10.3760.10 4 166 8.5E-49 T 28-03-2018 IPR007686 YutG/PgpA domain GO:0006629|GO:0008962 ALX04_RS10490 3ba62795bdac01337f631a188e6630b5 166 PIRSF PIRSF019587 9 166 4.1E-61 T 28-03-2018 IPR026038 Putative phosphatidylglycerophosphatase ALX04_RS01625 c2487df7e4b65af9430ef157d6948973 508 SUPERFAMILY SSF53756 215 498 3.45E-49 T 28-03-2018 ALX04_RS01625 c2487df7e4b65af9430ef157d6948973 508 Pfam PF00534 Glycosyl transferases group 1 323 481 1.8E-31 T 28-03-2018 IPR001296 Glycosyl transferase, family 1 ALX04_RS01625 c2487df7e4b65af9430ef157d6948973 508 Gene3D G3DSA:3.40.50.2000 263 486 6.8E-35 T 28-03-2018 ALX04_RS07675 ab56500517990001f4f63844abbede2b 218 Pfam PF01966 HD domain 28 127 1.8E-9 T 28-03-2018 IPR006674 HD domain ALX04_RS07675 ab56500517990001f4f63844abbede2b 218 Gene3D G3DSA:1.10.3210.10 3 215 9.9E-18 T 28-03-2018 ALX04_RS07675 ab56500517990001f4f63844abbede2b 218 SMART SM00471 22 137 4.5E-7 T 28-03-2018 IPR003607 HD/PDEase domain ALX04_RS07675 ab56500517990001f4f63844abbede2b 218 SUPERFAMILY SSF109604 1 213 1.69E-68 T 28-03-2018 ALX04_RS11850 bfcd11cac7827e9fdff117615474be61 248 ProSitePatterns PS00383 Tyrosine specific protein phosphatases active site. 137 147 - T 28-03-2018 IPR016130 Protein-tyrosine phosphatase, active site GO:0004725|GO:0016311 ALX04_RS11850 bfcd11cac7827e9fdff117615474be61 248 Gene3D G3DSA:3.90.190.10 13 191 3.4E-26 T 28-03-2018 IPR029021 Protein-tyrosine phosphatase-like ALX04_RS11850 bfcd11cac7827e9fdff117615474be61 248 Pfam PF13350 Tyrosine phosphatase family 1 246 9.8E-64 T 28-03-2018 IPR026893 Tyrosine/serine-protein phosphatase IphP-type ALX04_RS11850 bfcd11cac7827e9fdff117615474be61 248 SUPERFAMILY SSF52799 2 246 2.97E-56 T 28-03-2018 IPR029021 Protein-tyrosine phosphatase-like ALX04_RS04980 8029d6ffc8f40eab82a9be772f60488d 112 Pfam PF12844 Helix-turn-helix domain 6 64 5.0E-8 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 ALX04_RS04980 8029d6ffc8f40eab82a9be772f60488d 112 SUPERFAMILY SSF47413 3 67 8.45E-11 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 ALX04_RS04980 8029d6ffc8f40eab82a9be772f60488d 112 SMART SM00530 6 59 3.9E-7 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 ALX04_RS04980 8029d6ffc8f40eab82a9be772f60488d 112 Gene3D G3DSA:1.10.260.40 3 111 5.7E-18 T 28-03-2018 ALX04_RS07950 d827a74ab4aed915ccf5c50e8288dc09 336 Pfam PF03099 Biotin/lipoate A/B protein ligase family 48 155 2.0E-7 T 28-03-2018 IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain GO:0006464 ALX04_RS07950 d827a74ab4aed915ccf5c50e8288dc09 336 Gene3D G3DSA:3.30.930.10 1 252 1.4E-60 T 28-03-2018 ALX04_RS07950 d827a74ab4aed915ccf5c50e8288dc09 336 Gene3D G3DSA:3.30.390.50 253 336 3.8E-23 T 28-03-2018 ALX04_RS07950 d827a74ab4aed915ccf5c50e8288dc09 336 Pfam PF10437 Bacterial lipoate protein ligase C-terminus 249 333 9.2E-26 T 28-03-2018 IPR019491 Lipoate protein ligase, C-terminal KEGG: 00785+6.3.1.20 ALX04_RS07950 d827a74ab4aed915ccf5c50e8288dc09 336 SUPERFAMILY SSF55681 1 247 5.88E-69 T 28-03-2018 ALX04_RS07950 d827a74ab4aed915ccf5c50e8288dc09 336 TIGRFAM TIGR00545 lipoyltrans: lipoyltransferase and lipoate-protein ligase 4 326 1.8E-96 T 28-03-2018 IPR004562 Lipoyltransferase/lipoate-protein ligase GO:0009249 KEGG: 00785+6.3.1.20|Reactome: R-HSA-389661 ALX04_RS07950 d827a74ab4aed915ccf5c50e8288dc09 336 SUPERFAMILY SSF82649 248 334 3.92E-23 T 28-03-2018 ALX04_RS05440 d59191c602e8d68f04645a525dd56c97 386 Gene3D G3DSA:3.90.1150.10 264 384 3.3E-27 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 ALX04_RS05440 d59191c602e8d68f04645a525dd56c97 386 PIRSF PIRSF005572 1 384 7.0E-111 T 28-03-2018 IPR016454 Cysteine desulfurase KEGG: 00730+2.8.1.7|MetaCyc: PWY-6823|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7250 ALX04_RS05440 d59191c602e8d68f04645a525dd56c97 386 Gene3D G3DSA:3.40.640.10 12 256 1.2E-51 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 ALX04_RS05440 d59191c602e8d68f04645a525dd56c97 386 Pfam PF00266 Aminotransferase class-V 4 369 5.0E-76 T 28-03-2018 IPR000192 Aminotransferase class V domain ALX04_RS05440 d59191c602e8d68f04645a525dd56c97 386 SUPERFAMILY SSF53383 3 378 2.04E-96 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase ALX04_RS06680 0ed557752754033f279afcf2921f8b0a 508 TIGRFAM TIGR01542 A118_put_portal: phage portal protein, putative, A118 family 18 492 4.2E-163 T 28-03-2018 IPR006432 Portal protein, putative, A118-type ALX04_RS06680 0ed557752754033f279afcf2921f8b0a 508 PIRSF PIRSF011911 1 506 1.7E-227 T 28-03-2018 IPR006432 Portal protein, putative, A118-type ALX04_RS06680 0ed557752754033f279afcf2921f8b0a 508 Pfam PF05133 Phage portal protein, SPP1 Gp6-like 33 488 2.3E-61 T 28-03-2018 IPR021145 Portal protein ALX04_RS05145 e1c0bd5f2495ffe75f28f76b50754f64 313 Gene3D G3DSA:3.90.25.10 174 313 2.7E-37 T 28-03-2018 ALX04_RS05145 e1c0bd5f2495ffe75f28f76b50754f64 313 Pfam PF01370 NAD dependent epimerase/dehydratase family 3 241 3.9E-62 T 28-03-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 ALX04_RS05145 e1c0bd5f2495ffe75f28f76b50754f64 313 Gene3D G3DSA:3.40.50.720 2 173 3.8E-35 T 28-03-2018 ALX04_RS05145 e1c0bd5f2495ffe75f28f76b50754f64 313 SUPERFAMILY SSF51735 1 309 1.1E-85 T 28-03-2018 IPR016040 NAD(P)-binding domain ALX04_RS13775 29c4629787e8ca28e05fb4a5d2b898b0 248 SUPERFAMILY SSF53633 2 243 3.4E-51 T 28-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase ALX04_RS13775 29c4629787e8ca28e05fb4a5d2b898b0 248 PIRSF PIRSF000728 1 245 3.5E-73 T 28-03-2018 IPR004662 Acetylglutamate kinase GO:0003991|GO:0005737|GO:0006526 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400 ALX04_RS13775 29c4629787e8ca28e05fb4a5d2b898b0 248 Gene3D G3DSA:3.40.1160.10 1 245 3.5E-44 T 28-03-2018 ALX04_RS13775 29c4629787e8ca28e05fb4a5d2b898b0 248 Hamap MF_00082_B Acetylglutamate kinase [argB]. 1 244 25.389 T 28-03-2018 IPR004662 Acetylglutamate kinase GO:0003991|GO:0005737|GO:0006526 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400 ALX04_RS13775 29c4629787e8ca28e05fb4a5d2b898b0 248 Pfam PF00696 Amino acid kinase family 3 233 5.7E-41 T 28-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase ALX04_RS13775 29c4629787e8ca28e05fb4a5d2b898b0 248 TIGRFAM TIGR00761 argB: acetylglutamate kinase 5 231 2.6E-85 T 28-03-2018 IPR004662 Acetylglutamate kinase GO:0003991|GO:0005737|GO:0006526 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400 ALX04_RS11670 a245b2aa76f168750425f0b79fe74a74 790 SUPERFAMILY SSF53756 4 785 9.42E-271 T 28-03-2018 ALX04_RS11670 a245b2aa76f168750425f0b79fe74a74 790 Gene3D G3DSA:3.40.50.2000 5 449 1.0E-161 T 28-03-2018 ALX04_RS11670 a245b2aa76f168750425f0b79fe74a74 790 Pfam PF00343 Carbohydrate phosphorylase 93 784 1.3E-282 T 28-03-2018 IPR000811 Glycosyl transferase, family 35 GO:0005975|GO:0008184 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 ALX04_RS11670 a245b2aa76f168750425f0b79fe74a74 790 TIGRFAM TIGR02093 P_ylase: glycogen/starch/alpha-glucan phosphorylases 5 784 0.0 T 28-03-2018 IPR011833 Glycogen/starch/alpha-glucan phosphorylase GO:0004645|GO:0005975|GO:0030170 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 ALX04_RS11670 a245b2aa76f168750425f0b79fe74a74 790 Gene3D G3DSA:3.40.50.2000 450 769 2.8E-115 T 28-03-2018 ALX04_RS11670 a245b2aa76f168750425f0b79fe74a74 790 PIRSF PIRSF000460 2 790 3.1E-200 T 28-03-2018 IPR000811 Glycosyl transferase, family 35 GO:0005975|GO:0008184 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 ALX04_RS13835 28f11c1a610e3e8b5df5fd811bca3076 179 SMART SM00316 4 74 2.5E-24 T 28-03-2018 IPR022967 RNA-binding domain, S1 ALX04_RS13835 28f11c1a610e3e8b5df5fd811bca3076 179 Pfam PF00575 S1 RNA binding domain 4 74 4.4E-19 T 28-03-2018 IPR003029 S1 domain GO:0003676 ALX04_RS13835 28f11c1a610e3e8b5df5fd811bca3076 179 SUPERFAMILY SSF50249 2 76 1.03E-22 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold ALX04_RS13835 28f11c1a610e3e8b5df5fd811bca3076 179 Gene3D G3DSA:2.40.50.140 7 117 4.7E-26 T 28-03-2018 ALX04_RS04810 7a53f878ed12f3ec1e5ded2ec487b3af 126 Pfam PF06896 Phage tail assembly chaperone proteins, TAC 15 113 7.6E-19 T 28-03-2018 IPR009681 Phage tail assembly chaperone protein, Siphoviridae ALX04_RS15325 68d2091746c8a60704728fbdb33177c9 84 Pfam PF04226 Transglycosylase associated protein 34 78 9.6E-12 T 28-03-2018 IPR007341 Transglycosylase-associated protein GO:0016021 ALX04_RS12130 aec5f88044362f6cf02d80ee5419abc6 140 Gene3D G3DSA:2.60.40.790 3 140 1.5E-28 T 28-03-2018 IPR008978 HSP20-like chaperone ALX04_RS12130 aec5f88044362f6cf02d80ee5419abc6 140 Pfam PF00011 Hsp20/alpha crystallin family 38 140 5.9E-22 T 28-03-2018 IPR002068 Alpha crystallin/Hsp20 domain ALX04_RS12130 aec5f88044362f6cf02d80ee5419abc6 140 SUPERFAMILY SSF49764 11 132 4.01E-28 T 28-03-2018 IPR008978 HSP20-like chaperone ALX04_RS09670 7cd82766074c2ce34d8243e48d70fd96 85 SUPERFAMILY SSF46689 3 84 4.66E-12 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 ALX04_RS09670 7cd82766074c2ce34d8243e48d70fd96 85 Pfam PF08765 Mor transcription activator family 15 83 2.7E-8 T 28-03-2018 IPR014875 Mor transcription activator ALX04_RS09670 7cd82766074c2ce34d8243e48d70fd96 85 Gene3D G3DSA:1.10.10.60 47 85 1.2E-7 T 28-03-2018 ALX04_RS13810 c452a32078399252afebe35539a0b585 185 Hamap MF_00083 Peptidyl-tRNA hydrolase [pth]. 1 177 36.621 T 28-03-2018 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 ALX04_RS13810 c452a32078399252afebe35539a0b585 185 ProSitePatterns PS01195 Peptidyl-tRNA hydrolase signature 1. 14 27 - T 28-03-2018 IPR018171 Peptidyl-tRNA hydrolase, conserved site GO:0004045 MetaCyc: PWY-6308 ALX04_RS13810 c452a32078399252afebe35539a0b585 185 SUPERFAMILY SSF53178 1 185 1.7E-66 T 28-03-2018 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 ALX04_RS13810 c452a32078399252afebe35539a0b585 185 ProSitePatterns PS01196 Peptidyl-tRNA hydrolase signature 2. 107 117 - T 28-03-2018 IPR018171 Peptidyl-tRNA hydrolase, conserved site GO:0004045 MetaCyc: PWY-6308 ALX04_RS13810 c452a32078399252afebe35539a0b585 185 Pfam PF01195 Peptidyl-tRNA hydrolase 3 185 1.1E-59 T 28-03-2018 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 ALX04_RS13810 c452a32078399252afebe35539a0b585 185 Gene3D G3DSA:3.40.50.1470 1 185 4.4E-71 T 28-03-2018 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 ALX04_RS13810 c452a32078399252afebe35539a0b585 185 TIGRFAM TIGR00447 pth: aminoacyl-tRNA hydrolase 1 185 1.4E-67 T 28-03-2018 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 ALX04_RS04490 72931e59a473d4ef9658bdb41f50b722 80 Pfam PF00550 Phosphopantetheine attachment site 9 74 3.8E-12 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain ALX04_RS04490 72931e59a473d4ef9658bdb41f50b722 80 SUPERFAMILY SSF47336 2 79 8.24E-16 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain ALX04_RS04490 72931e59a473d4ef9658bdb41f50b722 80 TIGRFAM TIGR01688 dltC: D-alanine--poly(phosphoribitol) ligase, subunit 2 7 77 2.0E-31 T 28-03-2018 IPR003230 D-alanine--poly(phosphoribitol) ligase subunit 2 GO:0019350|GO:0036370 KEGG: 00473+6.1.1.13 ALX04_RS04490 72931e59a473d4ef9658bdb41f50b722 80 Gene3D G3DSA:1.10.1200.10 4 80 3.4E-13 T 28-03-2018 ALX04_RS04490 72931e59a473d4ef9658bdb41f50b722 80 Hamap MF_00565 D-alanine--poly(phosphoribitol) ligase subunit 2 [dltC]. 1 80 47.896 T 28-03-2018 IPR003230 D-alanine--poly(phosphoribitol) ligase subunit 2 GO:0019350|GO:0036370 KEGG: 00473+6.1.1.13 ALX04_RS11820 c8286772c00ae9da0768615d2443b7fe 217 Pfam PF00881 Nitroreductase family 19 196 3.9E-25 T 28-03-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 ALX04_RS11820 c8286772c00ae9da0768615d2443b7fe 217 SUPERFAMILY SSF55469 11 209 3.66E-52 T 28-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 ALX04_RS11820 c8286772c00ae9da0768615d2443b7fe 217 Gene3D G3DSA:3.40.109.10 2 215 3.0E-37 T 28-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 ALX04_RS14335 14df5a6398c88a3a55b79473a4ce5c08 336 Gene3D G3DSA:1.10.620.20 4 305 1.1E-71 T 28-03-2018 ALX04_RS14335 14df5a6398c88a3a55b79473a4ce5c08 336 SUPERFAMILY SSF47240 12 330 2.98E-95 T 28-03-2018 IPR009078 Ferritin-like superfamily ALX04_RS14335 14df5a6398c88a3a55b79473a4ce5c08 336 TIGRFAM TIGR04171 RNR_1b_NrdF: ribonucleoside-diphosphate reductase, class 1b, beta subunit 17 330 5.0E-143 T 28-03-2018 IPR026494 Ribonucleoside reductase subunit beta, NrdF GO:0005971|GO:0009263 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227 ALX04_RS14335 14df5a6398c88a3a55b79473a4ce5c08 336 Pfam PF00268 Ribonucleotide reductase, small chain 20 293 1.5E-78 T 28-03-2018 IPR000358 Ribonucleotide reductase small subunit family GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 ALX04_RS10435 593d277b4aeb6d5102cdc27d1e933f68 555 Pfam PF02028 BCCT, betaine/carnitine/choline family transporter 18 505 1.1E-122 T 28-03-2018 IPR000060 BCCT transporter family GO:0005215|GO:0006810|GO:0016020 ALX04_RS13130 c47e8774052a368ff45255cfde033cae 122 Pfam PF06993 Protein of unknown function (DUF1304) 10 119 4.8E-35 T 28-03-2018 IPR009732 Protein of unknown function DUF1304 ALX04_RS01780 b35642071b082cc72d5349d4fb37950f 420 SUPERFAMILY SSF55874 285 397 9.39E-10 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain ALX04_RS01780 b35642071b082cc72d5349d4fb37950f 420 Gene3D G3DSA:3.30.565.10 270 418 2.1E-11 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain ALX04_RS01780 b35642071b082cc72d5349d4fb37950f 420 Gene3D G3DSA:1.10.287.130 205 267 2.7E-10 T 28-03-2018 ALX04_RS01780 b35642071b082cc72d5349d4fb37950f 420 Pfam PF14501 GHKL domain 316 415 1.7E-9 T 28-03-2018 IPR032834 Sensor histidine kinase NatK, C-terminal domain ALX04_RS08435 f6c1f8ccb71a94bda4aca345a0a872f1 502 Pfam PF16993 Accessory Sec system protein Asp1 22 198 6.8E-11 T 28-03-2018 IPR022372 Accessory secretory system protein Asp1 GO:0015031 ALX04_RS08435 f6c1f8ccb71a94bda4aca345a0a872f1 502 SUPERFAMILY SSF53756 133 499 5.23E-45 T 28-03-2018 ALX04_RS08435 f6c1f8ccb71a94bda4aca345a0a872f1 502 Pfam PF00534 Glycosyl transferases group 1 331 482 5.6E-32 T 28-03-2018 IPR001296 Glycosyl transferase, family 1 ALX04_RS08435 f6c1f8ccb71a94bda4aca345a0a872f1 502 Gene3D G3DSA:3.40.50.2000 307 489 1.6E-31 T 28-03-2018 ALX04_RS11235 ba9a1f6c8335d330f1fbb4f75080b3a2 456 Pfam PF03611 PTS system sugar-specific permease component 11 407 1.8E-136 T 28-03-2018 IPR004703 Phosphotransferase system, sugar-specific permease component GO:0009401|GO:0016021 ALX04_RS02680 a08333cd598c0f48cc795d993d487b54 209 Pfam PF14278 Transcriptional regulator C-terminal region 101 174 2.0E-7 T 28-03-2018 ALX04_RS02680 a08333cd598c0f48cc795d993d487b54 209 Gene3D G3DSA:1.10.10.60 52 150 9.8E-6 T 28-03-2018 ALX04_RS02680 a08333cd598c0f48cc795d993d487b54 209 Gene3D G3DSA:1.10.10.60 10 51 4.2E-11 T 28-03-2018 ALX04_RS02680 a08333cd598c0f48cc795d993d487b54 209 SUPERFAMILY SSF46689 7 72 7.7E-13 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 ALX04_RS15500 6437a115a242a1c1469e0006af1f3b5c 216 Pfam PF01323 DSBA-like thioredoxin domain 3 208 8.5E-40 T 28-03-2018 IPR001853 DSBA-like thioredoxin domain GO:0015035 Reactome: R-HSA-156590 ALX04_RS15500 6437a115a242a1c1469e0006af1f3b5c 216 SUPERFAMILY SSF52833 1 213 1.18E-39 T 28-03-2018 IPR012336 Thioredoxin-like fold ALX04_RS15500 6437a115a242a1c1469e0006af1f3b5c 216 Gene3D G3DSA:3.40.30.10 1 209 2.2E-48 T 28-03-2018 ALX04_RS11335 12b6d111bc2b8e31013bc8e3cbb9c0d6 123 TIGRFAM TIGR02328 TIGR02328: conserved hypothetical protein 1 120 5.1E-69 T 28-03-2018 IPR012650 Conserved hypothetical protein CHP02328 ALX04_RS11335 12b6d111bc2b8e31013bc8e3cbb9c0d6 123 Gene3D G3DSA:1.10.440.10 2 94 3.0E-6 T 28-03-2018 IPR024796 T4 endonuclease V ALX04_RS11335 12b6d111bc2b8e31013bc8e3cbb9c0d6 123 Pfam PF03013 Pyrimidine dimer DNA glycosylase 1 109 8.2E-37 T 28-03-2018 IPR004260 Pyrimidine dimer DNA glycosylase ALX04_RS11335 12b6d111bc2b8e31013bc8e3cbb9c0d6 123 SUPERFAMILY SSF47077 10 80 8.37E-5 T 28-03-2018 ALX04_RS11475 fa9e944d307ff6ac078ab2dca44545fc 153 Pfam PF00582 Universal stress protein family 12 153 5.3E-15 T 28-03-2018 IPR006016 UspA GO:0006950 ALX04_RS11475 fa9e944d307ff6ac078ab2dca44545fc 153 SUPERFAMILY SSF52402 12 153 3.18E-16 T 28-03-2018 ALX04_RS11475 fa9e944d307ff6ac078ab2dca44545fc 153 PRINTS PR01438 Universal stress protein signature 114 126 2.9E-5 T 28-03-2018 IPR006015 Universal stress protein A ALX04_RS11475 fa9e944d307ff6ac078ab2dca44545fc 153 PRINTS PR01438 Universal stress protein signature 12 30 2.9E-5 T 28-03-2018 IPR006015 Universal stress protein A ALX04_RS11475 fa9e944d307ff6ac078ab2dca44545fc 153 PRINTS PR01438 Universal stress protein signature 131 153 2.9E-5 T 28-03-2018 IPR006015 Universal stress protein A ALX04_RS11475 fa9e944d307ff6ac078ab2dca44545fc 153 Gene3D G3DSA:3.40.50.620 14 153 5.1E-19 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold ALX04_RS01920 76b81e2cfc4a650c68445a3821b612c5 148 Pfam PF13673 Acetyltransferase (GNAT) domain 46 146 1.2E-14 T 28-03-2018 IPR000182 GNAT domain GO:0008080 ALX04_RS01920 76b81e2cfc4a650c68445a3821b612c5 148 SUPERFAMILY SSF55729 2 147 4.25E-30 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase ALX04_RS01920 76b81e2cfc4a650c68445a3821b612c5 148 Gene3D G3DSA:3.40.630.30 1 148 2.1E-26 T 28-03-2018 ALX04_RS05155 2d4ddd153159c007f79c49c7d05b4294 235 Pfam PF10609 NUBPL iron-transfer P-loop NTPase 48 216 4.0E-12 T 28-03-2018 IPR033756 Flagellum site-determining protein YlxH/ Fe-S cluster assembling factor NBP35 ALX04_RS05155 2d4ddd153159c007f79c49c7d05b4294 235 TIGRFAM TIGR01007 eps_fam: capsular exopolysaccharide family 28 231 7.8E-56 T 28-03-2018 IPR005702 Exopolysaccharide synthesis protein GO:0045226 ALX04_RS05155 2d4ddd153159c007f79c49c7d05b4294 235 SUPERFAMILY SSF52540 47 227 3.44E-38 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase ALX04_RS05155 2d4ddd153159c007f79c49c7d05b4294 235 Gene3D G3DSA:3.40.50.300 17 229 1.6E-37 T 28-03-2018 ALX04_RS04790 96d2000dd7b3f8e9a64727e0881c60c4 789 TIGRFAM TIGR01665 put_anti_recept: phage minor structural protein, N-terminal region 68 379 1.9E-23 T 28-03-2018 IPR007119 Phage minor structural protein, N-terminal domain ALX04_RS08795 faedf441613875819452f61d6945f1e3 276 SUPERFAMILY SSF56112 15 231 6.12E-20 T 28-03-2018 IPR011009 Protein kinase-like domain ALX04_RS08795 faedf441613875819452f61d6945f1e3 276 Gene3D G3DSA:3.90.1200.10 82 263 5.9E-13 T 28-03-2018 ALX04_RS08795 faedf441613875819452f61d6945f1e3 276 Pfam PF01636 Phosphotransferase enzyme family 39 227 1.7E-8 T 28-03-2018 IPR002575 Aminoglycoside phosphotransferase ALX04_RS11970 053ab2df2c0289f66fd852814859742f 259 SUPERFAMILY SSF81301 23 85 1.1E-8 T 28-03-2018 ALX04_RS11970 053ab2df2c0289f66fd852814859742f 259 Pfam PF13427 Domain of unknown function (DUF4111) 150 252 1.0E-31 T 28-03-2018 IPR025184 Domain of unknown function DUF4111 ALX04_RS11970 053ab2df2c0289f66fd852814859742f 259 Gene3D G3DSA:3.30.460.10 3 198 8.6E-10 T 28-03-2018 ALX04_RS11970 053ab2df2c0289f66fd852814859742f 259 Pfam PF01909 Nucleotidyltransferase domain 25 56 2.4E-5 T 28-03-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 ALX04_RS11970 053ab2df2c0289f66fd852814859742f 259 PIRSF PIRSF000819 3 254 5.1E-56 T 28-03-2018 IPR024172 Streptomycin 3''-adenylyltransferase GO:0009012|GO:0046677 ALX04_RS15155 bbd89fcc41dd32cf1e63fef974064711 217 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 13 110 1.2E-26 T 28-03-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 ALX04_RS15155 bbd89fcc41dd32cf1e63fef974064711 217 Gene3D G3DSA:1.10.3720.10 1 217 1.2E-40 T 28-03-2018 ALX04_RS15155 bbd89fcc41dd32cf1e63fef974064711 217 SUPERFAMILY SSF161098 15 211 1.83E-42 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 ALX04_RS15155 bbd89fcc41dd32cf1e63fef974064711 217 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 36 216 1.3E-19 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 ALX04_RS11990 9598579c2627f84fab492415b4e994c3 328 Pfam PF01891 Cobalt uptake substrate-specific transmembrane region 2 215 9.2E-56 T 28-03-2018 IPR002751 Cobalamin (vitamin B12) biosynthesis CbiM family GO:0000041|GO:0016021 ALX04_RS11990 9598579c2627f84fab492415b4e994c3 328 ProDom PD074023 BIOSYNTHESIS COBALAMIN CBIM COBALT PRECURSOR SIGNAL NICKEL MEMBRANE ABC PROTEIN 249 320 6.0E-35 T 28-03-2018 IPR020486 Uncharacterised protein family MJ1570 ALX04_RS11990 9598579c2627f84fab492415b4e994c3 328 Pfam PF13190 PDGLE domain 237 318 9.2E-10 T 28-03-2018 IPR025937 PDGLE domain ALX04_RS01900 d2836b11f9120341280d5af9624ee891 463 Pfam PF01554 MatE 19 178 1.3E-33 T 28-03-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 ALX04_RS01900 d2836b11f9120341280d5af9624ee891 463 Pfam PF01554 MatE 241 393 4.8E-19 T 28-03-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 ALX04_RS01900 d2836b11f9120341280d5af9624ee891 463 PIRSF PIRSF006603 1 432 8.1E-93 T 28-03-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 ALX04_RS01900 d2836b11f9120341280d5af9624ee891 463 TIGRFAM TIGR00797 matE: MATE efflux family protein 19 392 2.8E-59 T 28-03-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 ALX04_RS15775 ff589b0e4115816ef26d083d6b26c515 223 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 27 40 6.5E-10 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 ALX04_RS15775 ff589b0e4115816ef26d083d6b26c515 223 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 48 71 6.5E-10 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 ALX04_RS15775 ff589b0e4115816ef26d083d6b26c515 223 Gene3D G3DSA:1.10.357.10 77 217 3.5E-7 T 28-03-2018 ALX04_RS15775 ff589b0e4115816ef26d083d6b26c515 223 Pfam PF00440 Bacterial regulatory proteins, tetR family 27 73 1.7E-16 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 ALX04_RS15775 ff589b0e4115816ef26d083d6b26c515 223 Gene3D G3DSA:1.10.260.40 55 76 2.5E-5 T 28-03-2018 ALX04_RS15775 ff589b0e4115816ef26d083d6b26c515 223 SUPERFAMILY SSF46689 23 87 2.82E-16 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 ALX04_RS15775 ff589b0e4115816ef26d083d6b26c515 223 Gene3D G3DSA:1.10.10.60 2 54 2.4E-16 T 28-03-2018 ALX04_RS06860 6800ec5014c5d3f0dccd6b9778a6473a 373 Gene3D G3DSA:1.10.150.130 55 170 2.5E-14 T 28-03-2018 IPR023109 Integrase/recombinase, N-terminal ALX04_RS06860 6800ec5014c5d3f0dccd6b9778a6473a 373 Gene3D G3DSA:1.10.443.10 171 359 1.0E-31 T 28-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 ALX04_RS06860 6800ec5014c5d3f0dccd6b9778a6473a 373 SUPERFAMILY SSF56349 60 357 1.4E-50 T 28-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 ALX04_RS06860 6800ec5014c5d3f0dccd6b9778a6473a 373 Pfam PF14659 Phage integrase, N-terminal SAM-like domain 61 115 3.2E-6 T 28-03-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 ALX04_RS06860 6800ec5014c5d3f0dccd6b9778a6473a 373 Pfam PF00589 Phage integrase family 167 353 1.5E-21 T 28-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 ALX04_RS02295 5103b03141d7b6617630c09c39a7dc76 295 SMART SM00530 5 59 2.1E-6 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 ALX04_RS02295 5103b03141d7b6617630c09c39a7dc76 295 Gene3D G3DSA:1.25.40.10 110 272 0.063 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 ALX04_RS02295 5103b03141d7b6617630c09c39a7dc76 295 SUPERFAMILY SSF47413 8 59 7.7E-8 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 ALX04_RS02295 5103b03141d7b6617630c09c39a7dc76 295 Gene3D G3DSA:1.10.3100.10 1 109 4.0E-10 T 28-03-2018 IPR027910 YdiL-like domain ALX04_RS09900 a1c3eaf19f523b7c4588b46eefa0f111 255 SUPERFAMILY SSF52540 1 251 1.93E-69 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase ALX04_RS09900 a1c3eaf19f523b7c4588b46eefa0f111 255 Gene3D G3DSA:3.40.50.300 2 255 6.9E-65 T 28-03-2018 ALX04_RS09900 a1c3eaf19f523b7c4588b46eefa0f111 255 Pfam PF13614 AAA domain 3 178 2.8E-69 T 28-03-2018 IPR025669 AAA domain ALX04_RS09900 a1c3eaf19f523b7c4588b46eefa0f111 255 PIRSF PIRSF009320 2 85 3.1E-15 T 28-03-2018 ALX04_RS09900 a1c3eaf19f523b7c4588b46eefa0f111 255 PIRSF PIRSF009320 92 254 2.2E-7 T 28-03-2018 ALX04_RS09890 50e057d3e00ba3c050125e8223bbeb8d 63 PIRSF PIRSF037263 1 62 2.0E-37 T 28-03-2018 IPR009296 Protein of unknown function DUF951 ALX04_RS09890 50e057d3e00ba3c050125e8223bbeb8d 63 Pfam PF06107 Bacterial protein of unknown function (DUF951) 2 55 1.8E-32 T 28-03-2018 IPR009296 Protein of unknown function DUF951 ALX04_RS14320 5e8d4039a37fa546e39a9ab1f56f707e 222 Gene3D G3DSA:3.40.10.10 45 222 4.9E-12 T 28-03-2018 IPR035451 Ada-like domain ALX04_RS14320 5e8d4039a37fa546e39a9ab1f56f707e 222 SUPERFAMILY SSF57884 174 220 6.93E-6 T 28-03-2018 IPR004026 Ada DNA repair, metal-binding GO:0003677|GO:0006281|GO:0006355|GO:0008168|GO:0008270 ALX04_RS14345 697ea12a4caf0a4fed48430f30b21255 76 Gene3D G3DSA:3.40.30.10 2 75 2.8E-15 T 28-03-2018 ALX04_RS14345 697ea12a4caf0a4fed48430f30b21255 76 TIGRFAM TIGR02194 GlrX_NrdH: glutaredoxin-like protein NrdH 4 75 5.2E-38 T 28-03-2018 IPR011909 Glutaredoxin-like protein NrdH GO:0045454 ALX04_RS14345 697ea12a4caf0a4fed48430f30b21255 76 SUPERFAMILY SSF52833 3 73 2.96E-18 T 28-03-2018 IPR012336 Thioredoxin-like fold ALX04_RS14345 697ea12a4caf0a4fed48430f30b21255 76 Pfam PF00462 Glutaredoxin 4 60 3.6E-15 T 28-03-2018 IPR002109 Glutaredoxin GO:0009055|GO:0015035|GO:0045454 ALX04_RS07655 83749a497ff8fc9bfe94b68a33766363 282 SUPERFAMILY SSF53474 4 265 6.15E-37 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold ALX04_RS07655 83749a497ff8fc9bfe94b68a33766363 282 Gene3D G3DSA:3.40.50.1820 1 267 5.1E-26 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold ALX04_RS07655 83749a497ff8fc9bfe94b68a33766363 282 Pfam PF00756 Putative esterase 39 264 1.0E-17 T 28-03-2018 IPR000801 Putative esterase Reactome: R-HSA-156590 ALX04_RS15770 d65d69517df662b553fd87fa4e00dc90 415 Pfam PF12698 ABC-2 family transporter protein 18 406 7.3E-38 T 28-03-2018 ALX04_RS15185 c162c8775594b2b9e46f811aee23d3cb 443 Pfam PF13520 Amino acid permease 14 410 4.7E-63 T 28-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 ALX04_RS15185 c162c8775594b2b9e46f811aee23d3cb 443 PIRSF PIRSF006060 1 442 1.0E-82 T 28-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 ALX04_RS14875 ef02cf48225bd243392c3b41f47062c0 170 SMART SM00347 29 128 2.6E-11 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 ALX04_RS14875 ef02cf48225bd243392c3b41f47062c0 170 Pfam PF12802 MarR family 34 91 2.1E-7 T 28-03-2018 ALX04_RS14875 ef02cf48225bd243392c3b41f47062c0 170 SUPERFAMILY SSF46785 6 115 7.75E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS14875 ef02cf48225bd243392c3b41f47062c0 170 Gene3D G3DSA:1.10.10.10 2 155 1.1E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS12765 3c9738fdb947ce04d22a5bd5160abfec 229 Gene3D G3DSA:1.10.10.60 16 74 2.5E-19 T 28-03-2018 ALX04_RS12765 3c9738fdb947ce04d22a5bd5160abfec 229 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 28 41 1.3E-11 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 ALX04_RS12765 3c9738fdb947ce04d22a5bd5160abfec 229 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 49 72 1.3E-11 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 ALX04_RS12765 3c9738fdb947ce04d22a5bd5160abfec 229 SUPERFAMILY SSF46689 20 91 1.85E-17 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 ALX04_RS12765 3c9738fdb947ce04d22a5bd5160abfec 229 Gene3D G3DSA:1.10.357.10 75 220 8.6E-10 T 28-03-2018 ALX04_RS12765 3c9738fdb947ce04d22a5bd5160abfec 229 Pfam PF00440 Bacterial regulatory proteins, tetR family 28 74 4.6E-18 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 ALX04_RS11605 e6a3a0dad2d2c2a35b191f8270926cf7 200 Pfam PF00436 Single-strand binding protein family 2 102 3.2E-36 T 28-03-2018 IPR000424 Primosome PriB/single-strand DNA-binding GO:0003697 Reactome: R-HSA-2151201 ALX04_RS11605 e6a3a0dad2d2c2a35b191f8270926cf7 200 TIGRFAM TIGR00621 ssb: single-stranded DNA-binding protein 1 200 2.5E-45 T 28-03-2018 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Reactome: R-HSA-2151201 ALX04_RS11605 e6a3a0dad2d2c2a35b191f8270926cf7 200 PIRSF PIRSF002070 146 197 110.0 T 28-03-2018 ALX04_RS11605 e6a3a0dad2d2c2a35b191f8270926cf7 200 PIRSF PIRSF002070 1 157 1.2E-38 T 28-03-2018 ALX04_RS11605 e6a3a0dad2d2c2a35b191f8270926cf7 200 Gene3D G3DSA:2.40.50.140 1 111 3.0E-39 T 28-03-2018 ALX04_RS11605 e6a3a0dad2d2c2a35b191f8270926cf7 200 Hamap MF_00984 Single-stranded DNA-binding protein. 2 107 35.236 T 28-03-2018 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Reactome: R-HSA-2151201 ALX04_RS11605 e6a3a0dad2d2c2a35b191f8270926cf7 200 SUPERFAMILY SSF50249 1 161 6.28E-50 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold ALX04_RS10005 33463957a472dc583c13095713bb87ba 251 TIGRFAM TIGR00245 TIGR00245: TIGR00245 family protein 6 250 4.2E-80 T 28-03-2018 IPR005226 UPF0014 family ALX04_RS10005 33463957a472dc583c13095713bb87ba 251 Pfam PF03649 Uncharacterised protein family (UPF0014) 8 244 2.7E-81 T 28-03-2018 IPR005226 UPF0014 family ALX04_RS15265 1560877f6ca616b3b849c4aa8c7d209e 215 Pfam PF09335 SNARE associated Golgi protein 46 170 3.8E-20 T 28-03-2018 IPR032816 SNARE associated Golgi protein ALX04_RS13865 4b316423ce459322c8eeac8752684c9b 499 Hamap MF_00252 Lysine--tRNA ligase [lysS]. 14 496 44.196 T 28-03-2018 IPR002313 Lysine-tRNA ligase, class II GO:0004824|GO:0005524|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 ALX04_RS13865 4b316423ce459322c8eeac8752684c9b 499 PRINTS PR00982 Lysyl-tRNA synthetase signature 255 272 1.4E-38 T 28-03-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 ALX04_RS13865 4b316423ce459322c8eeac8752684c9b 499 PRINTS PR00982 Lysyl-tRNA synthetase signature 378 394 1.4E-38 T 28-03-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 ALX04_RS13865 4b316423ce459322c8eeac8752684c9b 499 PRINTS PR00982 Lysyl-tRNA synthetase signature 208 224 1.4E-38 T 28-03-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 ALX04_RS13865 4b316423ce459322c8eeac8752684c9b 499 PRINTS PR00982 Lysyl-tRNA synthetase signature 237 250 1.4E-38 T 28-03-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 ALX04_RS13865 4b316423ce459322c8eeac8752684c9b 499 PRINTS PR00982 Lysyl-tRNA synthetase signature 192 202 1.4E-38 T 28-03-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 ALX04_RS13865 4b316423ce459322c8eeac8752684c9b 499 Gene3D G3DSA:2.40.50.140 8 148 5.6E-37 T 28-03-2018 ALX04_RS13865 4b316423ce459322c8eeac8752684c9b 499 TIGRFAM TIGR00499 lysS_bact: lysine--tRNA ligase 8 496 8.1E-209 T 28-03-2018 IPR002313 Lysine-tRNA ligase, class II GO:0004824|GO:0005524|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 ALX04_RS13865 4b316423ce459322c8eeac8752684c9b 499 Pfam PF00152 tRNA synthetases class II (D, K and N) 157 493 2.0E-81 T 28-03-2018 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 ALX04_RS13865 4b316423ce459322c8eeac8752684c9b 499 Gene3D G3DSA:3.30.930.10 149 493 5.1E-105 T 28-03-2018 ALX04_RS13865 4b316423ce459322c8eeac8752684c9b 499 SUPERFAMILY SSF55681 155 494 9.96E-120 T 28-03-2018 ALX04_RS13865 4b316423ce459322c8eeac8752684c9b 499 Pfam PF01336 OB-fold nucleic acid binding domain 63 137 2.4E-12 T 28-03-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 ALX04_RS13865 4b316423ce459322c8eeac8752684c9b 499 SUPERFAMILY SSF50249 6 148 3.92E-43 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold ALX04_RS11295 4a26c8feac12777b311dc6e56f498d4f 186 Pfam PF14602 Hexapeptide repeat of succinyl-transferase 95 108 0.08 T 28-03-2018 IPR001451 Hexapeptide repeat ALX04_RS11295 4a26c8feac12777b311dc6e56f498d4f 186 SUPERFAMILY SSF51161 6 185 4.3E-43 T 28-03-2018 IPR011004 Trimeric LpxA-like ALX04_RS11295 4a26c8feac12777b311dc6e56f498d4f 186 SMART SM01266 6 60 6.2E-18 T 28-03-2018 IPR024688 Maltose/galactoside acetyltransferase GO:0016407 ALX04_RS11295 4a26c8feac12777b311dc6e56f498d4f 186 Pfam PF12464 Maltose acetyltransferase 8 59 5.2E-14 T 28-03-2018 IPR024688 Maltose/galactoside acetyltransferase GO:0016407 ALX04_RS11295 4a26c8feac12777b311dc6e56f498d4f 186 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 133 167 2.3E-7 T 28-03-2018 IPR001451 Hexapeptide repeat ALX04_RS11295 4a26c8feac12777b311dc6e56f498d4f 186 Gene3D G3DSA:2.160.10.10 2 186 5.7E-43 T 28-03-2018 ALX04_RS00015 01367524c7812fb4097775bf04f10bf5 164 Gene3D G3DSA:3.40.50.300 2 163 2.6E-13 T 28-03-2018 ALX04_RS00015 01367524c7812fb4097775bf04f10bf5 164 SUPERFAMILY SSF52540 5 131 4.26E-15 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase ALX04_RS00015 01367524c7812fb4097775bf04f10bf5 164 Pfam PF13671 AAA domain 5 119 3.9E-9 T 28-03-2018 ALX04_RS03315 79c378667f5a6a8e63b62604a8247611 312 Gene3D G3DSA:3.30.70.890 183 310 1.5E-29 T 28-03-2018 IPR013750 GHMP kinase, C-terminal domain ALX04_RS03315 79c378667f5a6a8e63b62604a8247611 312 SUPERFAMILY SSF55060 172 307 9.71E-32 T 28-03-2018 IPR013750 GHMP kinase, C-terminal domain ALX04_RS03315 79c378667f5a6a8e63b62604a8247611 312 Pfam PF08544 GHMP kinases C terminal 221 299 1.5E-13 T 28-03-2018 IPR013750 GHMP kinase, C-terminal domain ALX04_RS03315 79c378667f5a6a8e63b62604a8247611 312 PRINTS PR00959 Mevalonate kinase family signature 136 155 7.8E-20 T 28-03-2018 ALX04_RS03315 79c378667f5a6a8e63b62604a8247611 312 PRINTS PR00959 Mevalonate kinase family signature 93 115 7.8E-20 T 28-03-2018 ALX04_RS03315 79c378667f5a6a8e63b62604a8247611 312 PRINTS PR00959 Mevalonate kinase family signature 266 283 7.8E-20 T 28-03-2018 ALX04_RS03315 79c378667f5a6a8e63b62604a8247611 312 PRINTS PR00959 Mevalonate kinase family signature 9 33 7.8E-20 T 28-03-2018 ALX04_RS03315 79c378667f5a6a8e63b62604a8247611 312 Pfam PF00288 GHMP kinases N terminal domain 88 151 3.5E-15 T 28-03-2018 IPR006204 GHMP kinase N-terminal domain GO:0005524 ALX04_RS03315 79c378667f5a6a8e63b62604a8247611 312 Gene3D G3DSA:3.30.230.10 64 182 1.6E-27 T 28-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup ALX04_RS03315 79c378667f5a6a8e63b62604a8247611 312 Gene3D G3DSA:3.30.230.10 3 63 1.4E-5 T 28-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup ALX04_RS03315 79c378667f5a6a8e63b62604a8247611 312 TIGRFAM TIGR00549 mevalon_kin: mevalonate kinase 9 281 2.4E-79 T 28-03-2018 IPR006205 Mevalonate kinase GO:0004496|GO:0005524|GO:0005737|GO:0008299 KEGG: 00900+2.7.1.36|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-2426168 ALX04_RS03315 79c378667f5a6a8e63b62604a8247611 312 SUPERFAMILY SSF54211 6 188 4.1E-39 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold ALX04_RS15880 8cb9849b1b6b6c8f72ba996d6f99b981 321 SUPERFAMILY SSF53098 163 312 1.63E-19 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 ALX04_RS15880 8cb9849b1b6b6c8f72ba996d6f99b981 321 Pfam PF00665 Integrase core domain 164 268 1.8E-8 T 28-03-2018 IPR001584 Integrase, catalytic core GO:0015074 ALX04_RS15880 8cb9849b1b6b6c8f72ba996d6f99b981 321 Gene3D G3DSA:3.30.420.10 156 320 8.3E-19 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 ALX04_RS01310 25486fce5b44fe9b72f9e5829a099ee6 451 TIGRFAM TIGR00791 gntP: transporter, gluconate:H+ symporter (GntP) family 1 449 7.2E-172 T 28-03-2018 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 ALX04_RS01310 25486fce5b44fe9b72f9e5829a099ee6 451 Pfam PF02447 GntP family permease 1 448 4.6E-159 T 28-03-2018 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 ALX04_RS01310 25486fce5b44fe9b72f9e5829a099ee6 451 PIRSF PIRSF002746 1 451 8.5E-164 T 28-03-2018 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 ALX04_RS07210 1dbef0b1937ff3926543964f3a6b6bfa 298 Pfam PF02645 Uncharacterised protein, DegV family COG1307 2 281 4.6E-60 T 28-03-2018 IPR003797 DegV ALX04_RS07210 1dbef0b1937ff3926543964f3a6b6bfa 298 SUPERFAMILY SSF82549 1 284 1.74E-72 T 28-03-2018 ALX04_RS07210 1dbef0b1937ff3926543964f3a6b6bfa 298 TIGRFAM TIGR00762 DegV: EDD domain protein, DegV family 3 281 4.6E-78 T 28-03-2018 IPR003797 DegV ALX04_RS07210 1dbef0b1937ff3926543964f3a6b6bfa 298 Gene3D G3DSA:3.40.50.10170 1 153 2.7E-40 T 28-03-2018 ALX04_RS07210 1dbef0b1937ff3926543964f3a6b6bfa 298 Gene3D G3DSA:3.30.1180.10 154 289 5.3E-23 T 28-03-2018 ALX04_RS07495 617d2b3caf9b6ed92c7a8a9192d89662 129 Gene3D G3DSA:1.10.10.10 1 74 2.9E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS07495 617d2b3caf9b6ed92c7a8a9192d89662 129 SMART SM00345 13 72 6.6E-16 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 ALX04_RS07495 617d2b3caf9b6ed92c7a8a9192d89662 129 SUPERFAMILY SSF46785 2 76 9.62E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS07495 617d2b3caf9b6ed92c7a8a9192d89662 129 Pfam PF00392 Bacterial regulatory proteins, gntR family 10 72 1.0E-14 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 ALX04_RS11455 6a539c60b0833e21f8551e57d66c2919 131 Hamap MF_01661 D-ribose pyranase [rbsD]. 1 131 31.558 T 28-03-2018 IPR023064 D-ribose pyranase GO:0016872 ALX04_RS11455 6a539c60b0833e21f8551e57d66c2919 131 Pfam PF05025 RbsD / FucU transport protein family 1 130 3.7E-47 T 28-03-2018 IPR007721 D-ribose pyranase RbsD/L-fucose mutarotase FucU GO:0005996|GO:0016853|GO:0048029 Reactome: R-HSA-6787639 ALX04_RS11455 6a539c60b0833e21f8551e57d66c2919 131 SUPERFAMILY SSF102546 1 131 8.63E-45 T 28-03-2018 IPR023750 RbsD-like domain GO:0005996|GO:0016853|GO:0048029 Reactome: R-HSA-6787639 ALX04_RS11455 6a539c60b0833e21f8551e57d66c2919 131 Gene3D G3DSA:3.40.1650.10 2 131 5.1E-36 T 28-03-2018 IPR023750 RbsD-like domain GO:0005996|GO:0016853|GO:0048029 Reactome: R-HSA-6787639 ALX04_RS03265 e4915293398dff8322ad7c48e0281fd9 499 PIRSF PIRSF006060 10 493 5.6E-83 T 28-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 ALX04_RS03265 e4915293398dff8322ad7c48e0281fd9 499 Pfam PF13520 Amino acid permease 33 440 4.5E-51 T 28-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 ALX04_RS10850 51c1ab8c6e562d47e1aa8ff828c1691e 184 Pfam PF00210 Ferritin-like domain 31 172 4.8E-12 T 28-03-2018 IPR008331 Ferritin/DPS protein domain GO:0006879|GO:0008199 ALX04_RS10850 51c1ab8c6e562d47e1aa8ff828c1691e 184 Gene3D G3DSA:1.20.1260.10 1 184 7.1E-36 T 28-03-2018 IPR012347 Ferritin-related ALX04_RS10850 51c1ab8c6e562d47e1aa8ff828c1691e 184 SUPERFAMILY SSF47240 3 174 7.22E-63 T 28-03-2018 IPR009078 Ferritin-like superfamily ALX04_RS01230 d1aa4c79d726db2e794bea3927ff55e3 100 Pfam PF02397 Bacterial sugar transferase 31 96 6.5E-22 T 28-03-2018 IPR003362 Bacterial sugar transferase ALX04_RS13200 91aa5f7041c16d1089bf3698a5f06db2 609 Pfam PF01266 FAD dependent oxidoreductase 21 349 4.4E-53 T 28-03-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 ALX04_RS13200 91aa5f7041c16d1089bf3698a5f06db2 609 SUPERFAMILY SSF54373 253 349 2.88E-12 T 28-03-2018 ALX04_RS13200 91aa5f7041c16d1089bf3698a5f06db2 609 SUPERFAMILY SSF51905 5 124 3.18E-30 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ALX04_RS13200 91aa5f7041c16d1089bf3698a5f06db2 609 SUPERFAMILY SSF51905 160 250 3.18E-30 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ALX04_RS13200 91aa5f7041c16d1089bf3698a5f06db2 609 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 94 106 1.2E-26 T 28-03-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 ALX04_RS13200 91aa5f7041c16d1089bf3698a5f06db2 609 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 33 43 1.2E-26 T 28-03-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 ALX04_RS13200 91aa5f7041c16d1089bf3698a5f06db2 609 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 425 437 1.2E-26 T 28-03-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 ALX04_RS13200 91aa5f7041c16d1089bf3698a5f06db2 609 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 20 32 1.2E-26 T 28-03-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 ALX04_RS13200 91aa5f7041c16d1089bf3698a5f06db2 609 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 49 61 1.2E-26 T 28-03-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 ALX04_RS13200 91aa5f7041c16d1089bf3698a5f06db2 609 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 343 349 1.2E-26 T 28-03-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 ALX04_RS13200 91aa5f7041c16d1089bf3698a5f06db2 609 Gene3D G3DSA:3.30.9.10 222 350 2.0E-42 T 28-03-2018 ALX04_RS13200 91aa5f7041c16d1089bf3698a5f06db2 609 Gene3D G3DSA:3.50.50.60 3 221 1.0E-10 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ALX04_RS13200 91aa5f7041c16d1089bf3698a5f06db2 609 Pfam PF16901 C-terminal domain of alpha-glycerophosphate oxidase 464 586 7.4E-17 T 28-03-2018 IPR031656 Alpha-glycerophosphate oxidase, C-terminal KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 ALX04_RS06460 a3d9dc152f240b0a9e28bb94923be863 412 Gene3D G3DSA:3.40.640.10 32 269 1.1E-47 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 ALX04_RS06460 a3d9dc152f240b0a9e28bb94923be863 412 Hamap MF_00051 Serine hydroxymethyltransferase [glyA]. 2 411 51.045 T 28-03-2018 IPR001085 Serine hydroxymethyltransferase GO:0004372|GO:0006545|GO:0035999 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 ALX04_RS06460 a3d9dc152f240b0a9e28bb94923be863 412 SUPERFAMILY SSF53383 4 409 2.06E-169 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase ALX04_RS06460 a3d9dc152f240b0a9e28bb94923be863 412 Gene3D G3DSA:3.90.1150.10 270 410 1.3E-49 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 ALX04_RS06460 a3d9dc152f240b0a9e28bb94923be863 412 Pfam PF00464 Serine hydroxymethyltransferase 4 380 2.3E-167 T 28-03-2018 ALX04_RS06460 a3d9dc152f240b0a9e28bb94923be863 412 ProSitePatterns PS00096 Serine hydroxymethyltransferase pyridoxal-phosphate attachment site. 217 233 - T 28-03-2018 IPR019798 Serine hydroxymethyltransferase, pyridoxal phosphate binding site GO:0030170 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 ALX04_RS06460 a3d9dc152f240b0a9e28bb94923be863 412 PIRSF PIRSF000412 1 410 1.3E-161 T 28-03-2018 IPR001085 Serine hydroxymethyltransferase GO:0004372|GO:0006545|GO:0035999 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 ALX04_RS03115 886e023ad6c1cfbb0fb63fce3dddb571 288 Pfam PF01145 SPFH domain / Band 7 family 60 231 3.0E-21 T 28-03-2018 IPR001107 Band 7 domain ALX04_RS03115 886e023ad6c1cfbb0fb63fce3dddb571 288 SMART SM00244 56 221 8.3E-14 T 28-03-2018 IPR001107 Band 7 domain ALX04_RS03115 886e023ad6c1cfbb0fb63fce3dddb571 288 SUPERFAMILY SSF117892 95 222 4.05E-10 T 28-03-2018 IPR001107 Band 7 domain ALX04_RS12615 48b89cc03b99a2b52ae128990da631b9 182 Gene3D G3DSA:3.40.50.360 1 181 3.6E-35 T 28-03-2018 IPR029039 Flavoprotein-like domain ALX04_RS12615 48b89cc03b99a2b52ae128990da631b9 182 Pfam PF03358 NADPH-dependent FMN reductase 3 146 9.3E-32 T 28-03-2018 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 ALX04_RS12615 48b89cc03b99a2b52ae128990da631b9 182 SUPERFAMILY SSF52218 3 173 7.16E-46 T 28-03-2018 IPR029039 Flavoprotein-like domain ALX04_RS01725 6722a5bf13088a7b4040373e011ea83f 245 Pfam PF12679 ABC-2 family transporter protein 34 241 4.3E-8 T 28-03-2018 IPR032688 ABC-2 family transporter protein GO:0006810 ALX04_RS12885 55d132eadb7c1519dcdc34f6df917318 253 Pfam PF02517 CAAX protease self-immunity 101 199 6.3E-16 T 28-03-2018 IPR003675 CAAX amino terminal protease GO:0016020 Reactome: R-HSA-5689880 ALX04_RS14820 eba2d930a95a117ea859891f7777e918 187 SUPERFAMILY SSF54518 10 151 3.66E-11 T 28-03-2018 IPR025659 Tubby C-terminal-like domain ALX04_RS01800 5b2dab08d8b30b91a65bcc990035023c 221 Pfam PF02517 CAAX protease self-immunity 125 212 1.3E-16 T 28-03-2018 IPR003675 CAAX amino terminal protease GO:0016020 Reactome: R-HSA-5689880 ALX04_RS01255 83c214e72cfc1953d70b02652e9ee814 182 Gene3D G3DSA:1.10.1740.10 1 82 3.3E-7 T 28-03-2018 ALX04_RS01255 83c214e72cfc1953d70b02652e9ee814 182 Gene3D G3DSA:1.10.10.60 83 178 5.0E-5 T 28-03-2018 ALX04_RS15425 a4871210cdd303cbbfaee8a0a1a28b19 140 Gene3D G3DSA:1.10.10.60 30 76 2.7E-9 T 28-03-2018 ALX04_RS15425 a4871210cdd303cbbfaee8a0a1a28b19 140 Gene3D G3DSA:1.10.10.60 80 135 5.1E-4 T 28-03-2018 ALX04_RS15425 a4871210cdd303cbbfaee8a0a1a28b19 140 Pfam PF13936 Helix-turn-helix domain 32 70 1.6E-9 T 28-03-2018 IPR025246 Transposase IS30-like HTH domain ALX04_RS14045 392624b691b12de8164b7615d0f0c7e2 273 TIGRFAM TIGR01528 NMN_trans_PnuC: nicotinamide mononucleotide transporter PnuC 75 260 6.4E-27 T 28-03-2018 IPR006419 Nicotinamide mononucleotide transporter PnuC GO:0016020|GO:0034257|GO:0034258 ALX04_RS14045 392624b691b12de8164b7615d0f0c7e2 273 Pfam PF04973 Nicotinamide mononucleotide transporter 75 259 3.6E-26 T 28-03-2018 IPR006419 Nicotinamide mononucleotide transporter PnuC GO:0016020|GO:0034257|GO:0034258 ALX04_RS04850 16cf9f7065935b421536d9c973310da2 382 TIGRFAM TIGR01537 portal_HK97: phage portal protein, HK97 family 39 353 2.1E-47 T 28-03-2018 IPR006427 Phage portal protein, HK97 ALX04_RS04850 16cf9f7065935b421536d9c973310da2 382 Pfam PF04860 Phage portal protein 48 353 2.2E-45 T 28-03-2018 IPR006944 Bacteriophage/Gene transfer agent portal protein ALX04_RS08945 4a4b5c4b7d503453797e62c83eecab80 490 Pfam PF01977 3-octaprenyl-4-hydroxybenzoate carboxy-lyase 21 433 3.2E-98 T 28-03-2018 IPR002830 UbiD decarboxylyase family GO:0016831 KEGG: 00130+4.1.1.98|MetaCyc: PWY-5855|MetaCyc: PWY-5856|MetaCyc: PWY-5857|MetaCyc: PWY-6708|MetaCyc: PWY-6978 ALX04_RS08945 4a4b5c4b7d503453797e62c83eecab80 490 SUPERFAMILY SSF50475 7 321 2.86E-58 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 ALX04_RS08945 4a4b5c4b7d503453797e62c83eecab80 490 Gene3D G3DSA:3.40.1670.10 323 478 2.2E-34 T 28-03-2018 ALX04_RS08945 4a4b5c4b7d503453797e62c83eecab80 490 SUPERFAMILY SSF143968 325 482 1.83E-35 T 28-03-2018 ALX04_RS07905 99063d018401f48029467c2f91ab359f 484 Hamap MF_01931 Amidophosphoribosyltransferase [purF]. 11 457 45.071 T 28-03-2018 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 ALX04_RS07905 99063d018401f48029467c2f91ab359f 484 Pfam PF00156 Phosphoribosyl transferase domain 286 383 1.1E-8 T 28-03-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 ALX04_RS07905 99063d018401f48029467c2f91ab359f 484 SUPERFAMILY SSF56235 12 265 4.03E-63 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal ALX04_RS07905 99063d018401f48029467c2f91ab359f 484 Gene3D G3DSA:3.60.20.10 12 254 9.4E-55 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal ALX04_RS07905 99063d018401f48029467c2f91ab359f 484 PIRSF PIRSF000485 8 473 2.4E-167 T 28-03-2018 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 ALX04_RS07905 99063d018401f48029467c2f91ab359f 484 SUPERFAMILY SSF53271 248 465 1.31E-71 T 28-03-2018 IPR029057 Phosphoribosyltransferase-like ALX04_RS07905 99063d018401f48029467c2f91ab359f 484 Gene3D G3DSA:3.40.50.2020 268 436 1.2E-31 T 28-03-2018 ALX04_RS07905 99063d018401f48029467c2f91ab359f 484 Pfam PF13522 Glutamine amidotransferase domain 75 205 1.4E-18 T 28-03-2018 ALX04_RS07905 99063d018401f48029467c2f91ab359f 484 TIGRFAM TIGR01134 purF: amidophosphoribosyltransferase 12 458 3.7E-154 T 28-03-2018 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 ALX04_RS09810 8402fad31c524aca9ed121ae6938c7b5 120 Pfam PF13273 Protein of unknown function (DUF4064) 16 97 1.5E-11 T 28-03-2018 IPR025273 Domain of unknown function DUF4064 ALX04_RS09810 8402fad31c524aca9ed121ae6938c7b5 120 Gene3D G3DSA:1.20.1070.10 1 114 3.8E-4 T 28-03-2018 ALX04_RS02895 d5896cb26292cab5696f6ff8f53ad9fb 85 Gene3D G3DSA:3.30.300.20 1 79 1.5E-13 T 28-03-2018 IPR015946 K homology domain-like, alpha/beta ALX04_RS02895 d5896cb26292cab5696f6ff8f53ad9fb 85 Hamap MF_00088 UPF0109 protein . 4 78 18.801 T 28-03-2018 IPR020627 Uncharacterised protein family UPF0109 ALX04_RS02895 d5896cb26292cab5696f6ff8f53ad9fb 85 Pfam PF13083 KH domain 5 77 4.9E-20 T 28-03-2018 ALX04_RS12650 2be2e558663f6b9451b021d43b4fbf81 244 TIGRFAM TIGR03581 EF_0839: conserved hypothetical protein EF_0839/AHA_3917 10 243 3.5E-117 T 28-03-2018 IPR010763 2-dehydro-3-deoxy-phosphogluconate aldolase KEGG: 00030+4.1.2.14|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 ALX04_RS12650 2be2e558663f6b9451b021d43b4fbf81 244 Pfam PF07071 KDGP aldolase 10 224 1.7E-97 T 28-03-2018 IPR010763 2-dehydro-3-deoxy-phosphogluconate aldolase KEGG: 00030+4.1.2.14|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 ALX04_RS12650 2be2e558663f6b9451b021d43b4fbf81 244 Gene3D G3DSA:3.20.20.70 4 244 4.1E-107 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 ALX04_RS09365 708aa412e9735595c3219fb8df827d01 399 Pfam PF01546 Peptidase family M20/M25/M40 76 387 5.6E-25 T 28-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 ALX04_RS09365 708aa412e9735595c3219fb8df827d01 399 TIGRFAM TIGR01891 amidohydrolases: amidohydrolase 18 380 5.6E-97 T 28-03-2018 IPR017439 Amidohydrolase GO:0016787 ALX04_RS09365 708aa412e9735595c3219fb8df827d01 399 Pfam PF07687 Peptidase dimerisation domain 184 283 7.7E-12 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain ALX04_RS09365 708aa412e9735595c3219fb8df827d01 399 Gene3D G3DSA:3.40.630.10 1 270 8.2E-64 T 28-03-2018 ALX04_RS09365 708aa412e9735595c3219fb8df827d01 399 Gene3D G3DSA:3.40.630.10 271 399 1.5E-17 T 28-03-2018 ALX04_RS09365 708aa412e9735595c3219fb8df827d01 399 PIRSF PIRSF005962 2 396 1.9E-111 T 28-03-2018 IPR017439 Amidohydrolase GO:0016787 ALX04_RS09365 708aa412e9735595c3219fb8df827d01 399 SUPERFAMILY SSF55031 188 300 1.96E-27 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain ALX04_RS09365 708aa412e9735595c3219fb8df827d01 399 SUPERFAMILY SSF53187 302 394 3.43E-78 T 28-03-2018 ALX04_RS09365 708aa412e9735595c3219fb8df827d01 399 SUPERFAMILY SSF53187 6 201 3.43E-78 T 28-03-2018 ALX04_RS14430 ed474afde541ef4b0b8ad36566e6dd12 284 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 108 276 1.7E-14 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 ALX04_RS14430 ed474afde541ef4b0b8ad36566e6dd12 284 SUPERFAMILY SSF161098 84 267 5.76E-26 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 ALX04_RS14430 ed474afde541ef4b0b8ad36566e6dd12 284 Gene3D G3DSA:1.10.3720.10 31 284 1.4E-23 T 28-03-2018 ALX04_RS07240 63e28d5e9c25499dc306a5a566af6bd5 302 Gene3D G3DSA:1.10.3470.10 1 283 1.6E-33 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like ALX04_RS07240 63e28d5e9c25499dc306a5a566af6bd5 302 Pfam PF02653 Branched-chain amino acid transport system / permease component 4 275 5.4E-25 T 28-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 ALX04_RS00995 93ed75d3fea30c4728689164139c735c 372 Gene3D G3DSA:3.40.50.2000 207 352 4.6E-35 T 28-03-2018 ALX04_RS00995 93ed75d3fea30c4728689164139c735c 372 Gene3D G3DSA:3.40.50.2000 5 206 3.1E-77 T 28-03-2018 ALX04_RS00995 93ed75d3fea30c4728689164139c735c 372 SUPERFAMILY SSF53756 4 367 1.44E-134 T 28-03-2018 ALX04_RS00995 93ed75d3fea30c4728689164139c735c 372 Pfam PF02350 UDP-N-acetylglucosamine 2-epimerase 26 365 5.8E-117 T 28-03-2018 IPR003331 UDP-N-acetylglucosamine 2-epimerase domain Reactome: R-HSA-4085001 ALX04_RS00995 93ed75d3fea30c4728689164139c735c 372 TIGRFAM TIGR00236 wecB: UDP-N-acetylglucosamine 2-epimerase 5 366 1.6E-156 T 28-03-2018 IPR029767 UDP-N-acetylglucosamine 2-epimerase WecB-like GO:0008761 ALX04_RS13935 4108da1f95245568c4073fbf9c7d723e 64 Gene3D G3DSA:1.10.260.40 1 62 1.5E-7 T 28-03-2018 ALX04_RS13935 4108da1f95245568c4073fbf9c7d723e 64 Pfam PF01381 Helix-turn-helix 14 56 1.8E-6 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 ALX04_RS13935 4108da1f95245568c4073fbf9c7d723e 64 SUPERFAMILY SSF47413 4 60 6.22E-8 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 ALX04_RS10815 9f6601512d6fbaec85d48ed1a70b189c 231 Pfam PF02698 DUF218 domain 28 152 3.2E-14 T 28-03-2018 IPR003848 Domain of unknown function DUF218 ALX04_RS10815 9f6601512d6fbaec85d48ed1a70b189c 231 Gene3D G3DSA:1.10.3620.10 126 226 1.7E-24 T 28-03-2018 ALX04_RS07685 bcbc73997749ad1bb63191592eed507c 174 Pfam PF08876 Domain of unknown function (DUF1836) 20 116 2.0E-29 T 28-03-2018 IPR014975 Protein of unknown function DUF1836 ALX04_RS08420 1f8d9ccc53609b437441429fa46a7a66 185 SUPERFAMILY SSF55729 6 152 8.7E-31 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase ALX04_RS08420 1f8d9ccc53609b437441429fa46a7a66 185 Pfam PF13302 Acetyltransferase (GNAT) domain 12 150 2.8E-21 T 28-03-2018 IPR000182 GNAT domain GO:0008080 ALX04_RS08420 1f8d9ccc53609b437441429fa46a7a66 185 Gene3D G3DSA:3.40.630.30 2 183 2.9E-20 T 28-03-2018 ALX04_RS07860 1c995efda7e768d6663b256903b7e5b3 300 Gene3D G3DSA:3.40.50.720 1 283 2.8E-14 T 28-03-2018 ALX04_RS07860 1c995efda7e768d6663b256903b7e5b3 300 SUPERFAMILY SSF51735 1 287 2.98E-30 T 28-03-2018 IPR016040 NAD(P)-binding domain ALX04_RS07860 1c995efda7e768d6663b256903b7e5b3 300 Pfam PF05368 NmrA-like family 3 221 8.0E-13 T 28-03-2018 IPR008030 NmrA-like domain Reactome: R-HSA-70635 ALX04_RS04750 a29df41e574a07a7ea38b6692e202387 403 Pfam PF01098 Cell cycle protein 22 386 3.3E-71 T 28-03-2018 IPR001182 Probable peptidoglycan glycosyltransferase FtsW/RodA GO:0016021|GO:0051301 ALX04_RS04750 a29df41e574a07a7ea38b6692e202387 403 ProSitePatterns PS00428 Cell cycle proteins ftsW / rodA / spoVE signature. 349 373 - T 28-03-2018 IPR018365 Cell cycle, FtsW / RodA / SpoVE, conserved site GO:0007049|GO:0016021 ALX04_RS02485 62cc317ba84c2a514220ff0808adf82d 393 Gene3D G3DSA:3.60.21.10 72 278 1.1E-21 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like ALX04_RS02485 62cc317ba84c2a514220ff0808adf82d 393 Gene3D G3DSA:3.60.21.10 1 71 3.2E-14 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like ALX04_RS02485 62cc317ba84c2a514220ff0808adf82d 393 Pfam PF12320 Type 5 capsule protein repressor C-terminal domain 278 367 3.9E-8 T 28-03-2018 IPR026843 Nuclease SbcCD subunit D, C-terminal domain ALX04_RS02485 62cc317ba84c2a514220ff0808adf82d 393 Pfam PF00149 Calcineurin-like phosphoesterase 1 225 1.2E-14 T 28-03-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 ALX04_RS02485 62cc317ba84c2a514220ff0808adf82d 393 SUPERFAMILY SSF56300 1 315 8.36E-48 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like ALX04_RS02485 62cc317ba84c2a514220ff0808adf82d 393 TIGRFAM TIGR00619 sbcd: exonuclease SbcCD, D subunit 1 250 5.7E-44 T 28-03-2018 IPR004593 Nuclease SbcCD subunit D GO:0004519|GO:0006259|GO:0008408 ALX04_RS02405 713a66aec5d44330ede6b8ba1243c840 104 Pfam PF01985 CRS1 / YhbY (CRM) domain 4 86 6.0E-19 T 28-03-2018 IPR001890 RNA-binding, CRM domain GO:0003723 ALX04_RS02405 713a66aec5d44330ede6b8ba1243c840 104 ProDom PD010559 RNA-BINDING YHBY UPF0044 PREDICTED RNA RIBOSOMAL CONTAINING KH BINDING DOMAIN 11 88 2.0E-39 T 28-03-2018 IPR001890 RNA-binding, CRM domain GO:0003723 ALX04_RS02405 713a66aec5d44330ede6b8ba1243c840 104 SUPERFAMILY SSF75471 3 92 1.96E-25 T 28-03-2018 IPR001890 RNA-binding, CRM domain GO:0003723 ALX04_RS02405 713a66aec5d44330ede6b8ba1243c840 104 TIGRFAM TIGR00253 RNA_bind_YhbY: putative RNA-binding protein, YhbY family 4 91 3.8E-25 T 28-03-2018 IPR017924 RNA-binding protein YhbY GO:0003723 ALX04_RS02405 713a66aec5d44330ede6b8ba1243c840 104 Gene3D G3DSA:3.30.110.60 3 98 7.8E-24 T 28-03-2018 IPR001890 RNA-binding, CRM domain GO:0003723 ALX04_RS02405 713a66aec5d44330ede6b8ba1243c840 104 SMART SM01103 4 87 1.6E-34 T 28-03-2018 IPR001890 RNA-binding, CRM domain GO:0003723 ALX04_RS15020 042e63629780d4729a3fe3c61c52c002 435 Pfam PF00860 Permease family 20 394 9.6E-45 T 28-03-2018 IPR006043 Xanthine/uracil/vitamin C permease GO:0005215|GO:0006810|GO:0016020|GO:0055085 ALX04_RS15020 042e63629780d4729a3fe3c61c52c002 435 PIRSF PIRSF005353 1 435 7.2E-167 T 28-03-2018 IPR026033 Purine permease PbuG-like ALX04_RS01115 2202220e548cd0069424d892a32b4309 218 Pfam PF02397 Bacterial sugar transferase 21 212 4.3E-60 T 28-03-2018 IPR003362 Bacterial sugar transferase ALX04_RS04860 4da354a29ad85d3e28dc8ef169359e95 628 Pfam PF03354 Phage Terminase 106 594 3.5E-57 T 28-03-2018 IPR005021 Terminase large subunit, Lambdalikevirus-type ALX04_RS15385 0777f8763aedde02daa577bf13a208fb 396 SUPERFAMILY SSF116734 7 207 9.48E-37 T 28-03-2018 ALX04_RS15385 0777f8763aedde02daa577bf13a208fb 396 Gene3D G3DSA:3.90.220.20 176 381 3.8E-20 T 28-03-2018 ALX04_RS15385 0777f8763aedde02daa577bf13a208fb 396 SUPERFAMILY SSF116734 198 395 2.94E-28 T 28-03-2018 ALX04_RS15385 0777f8763aedde02daa577bf13a208fb 396 Gene3D G3DSA:3.90.220.20 1 160 1.4E-24 T 28-03-2018 ALX04_RS15385 0777f8763aedde02daa577bf13a208fb 396 Pfam PF01420 Type I restriction modification DNA specificity domain 18 185 7.0E-9 T 28-03-2018 IPR000055 Restriction endonuclease, type I, HsdS GO:0003677|GO:0006304 ALX04_RS15385 0777f8763aedde02daa577bf13a208fb 396 Pfam PF01420 Type I restriction modification DNA specificity domain 249 385 2.7E-6 T 28-03-2018 IPR000055 Restriction endonuclease, type I, HsdS GO:0003677|GO:0006304 ALX04_RS10010 6091e5f176e808d39c486ad013dde49e 216 Pfam PF00005 ABC transporter 20 163 1.6E-30 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 ALX04_RS10010 6091e5f176e808d39c486ad013dde49e 216 Gene3D G3DSA:3.40.50.300 1 216 7.6E-58 T 28-03-2018 ALX04_RS10010 6091e5f176e808d39c486ad013dde49e 216 SMART SM00382 29 211 3.3E-12 T 28-03-2018 IPR003593 AAA+ ATPase domain ALX04_RS10010 6091e5f176e808d39c486ad013dde49e 216 ProSitePatterns PS00211 ABC transporters family signature. 135 149 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 ALX04_RS10010 6091e5f176e808d39c486ad013dde49e 216 SUPERFAMILY SSF52540 4 212 5.98E-55 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase ALX04_RS08600 3c790df9f417e7876e2332e2d6e92acc 283 ProSitePatterns PS00798 Aldo/keto reductase family signature 1. 39 56 - T 28-03-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 ALX04_RS08600 3c790df9f417e7876e2332e2d6e92acc 283 PIRSF PIRSF000097 1 115 4.1E-36 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 ALX04_RS08600 3c790df9f417e7876e2332e2d6e92acc 283 PIRSF PIRSF000097 111 275 1.8E-40 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 ALX04_RS08600 3c790df9f417e7876e2332e2d6e92acc 283 Gene3D G3DSA:3.20.20.100 1 273 4.1E-93 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain ALX04_RS08600 3c790df9f417e7876e2332e2d6e92acc 283 SUPERFAMILY SSF51430 2 261 9.69E-88 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain ALX04_RS08600 3c790df9f417e7876e2332e2d6e92acc 283 ProSitePatterns PS00062 Aldo/keto reductase family signature 2. 120 137 - T 28-03-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 ALX04_RS08600 3c790df9f417e7876e2332e2d6e92acc 283 Pfam PF00248 Aldo/keto reductase family 15 258 2.7E-53 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain ALX04_RS08600 3c790df9f417e7876e2332e2d6e92acc 283 ProSitePatterns PS00063 Aldo/keto reductase family putative active site signature. 226 241 - T 28-03-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 ALX04_RS08600 3c790df9f417e7876e2332e2d6e92acc 283 PRINTS PR00069 Aldo-keto reductase signature 35 59 2.3E-42 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 ALX04_RS08600 3c790df9f417e7876e2332e2d6e92acc 283 PRINTS PR00069 Aldo-keto reductase signature 91 109 2.3E-42 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 ALX04_RS08600 3c790df9f417e7876e2332e2d6e92acc 283 PRINTS PR00069 Aldo-keto reductase signature 120 137 2.3E-42 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 ALX04_RS08600 3c790df9f417e7876e2332e2d6e92acc 283 PRINTS PR00069 Aldo-keto reductase signature 154 183 2.3E-42 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 ALX04_RS08600 3c790df9f417e7876e2332e2d6e92acc 283 PRINTS PR00069 Aldo-keto reductase signature 193 217 2.3E-42 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 ALX04_RS08445 9c4a5998f428c7baa8d218f2c2dd2372 327 Gene3D G3DSA:3.10.350.10 22 77 1.0E-12 T 28-03-2018 ALX04_RS08445 9c4a5998f428c7baa8d218f2c2dd2372 327 SMART SM00257 28 72 8.3E-11 T 28-03-2018 IPR018392 LysM domain ALX04_RS08445 9c4a5998f428c7baa8d218f2c2dd2372 327 Pfam PF01476 LysM domain 30 70 8.5E-11 T 28-03-2018 IPR018392 LysM domain ALX04_RS08445 9c4a5998f428c7baa8d218f2c2dd2372 327 SUPERFAMILY SSF54106 27 72 1.26E-7 T 28-03-2018 IPR018392 LysM domain ALX04_RS13450 affb3d8a30bb416e9d52691dd64ba9c0 453 PIRSF PIRSF006351 1 451 2.8E-128 T 28-03-2018 IPR004796 Phosphotransferase system, cellobiose-type IIC component GO:0008982|GO:0009401|GO:0016021 ALX04_RS13450 affb3d8a30bb416e9d52691dd64ba9c0 453 TIGRFAM TIGR00410 lacE: PTS system, lactose/cellobiose family IIC component 12 447 6.9E-105 T 28-03-2018 IPR004501 Phosphotransferase system, EIIC component, type 3 GO:0008982|GO:0009401|GO:0016021 ALX04_RS13450 affb3d8a30bb416e9d52691dd64ba9c0 453 Pfam PF02378 Phosphotransferase system, EIIC 29 379 2.7E-55 T 28-03-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 ALX04_RS04035 39c31f47e261073ba9824309b568ce45 256 Pfam PF01061 ABC-2 type transporter 12 220 8.5E-26 T 28-03-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 ALX04_RS04035 39c31f47e261073ba9824309b568ce45 256 PIRSF PIRSF006648 1 255 3.4E-63 T 28-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 ALX04_RS15765 51e467111561033851dab2a53c84fdcb 247 SUPERFAMILY SSF52540 7 224 4.41E-58 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase ALX04_RS15765 51e467111561033851dab2a53c84fdcb 247 SMART SM00382 30 209 7.0E-9 T 28-03-2018 IPR003593 AAA+ ATPase domain ALX04_RS15765 51e467111561033851dab2a53c84fdcb 247 Pfam PF00005 ABC transporter 21 162 1.9E-28 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 ALX04_RS15765 51e467111561033851dab2a53c84fdcb 247 Gene3D G3DSA:3.40.50.300 2 247 1.1E-60 T 28-03-2018 ALX04_RS15765 51e467111561033851dab2a53c84fdcb 247 ProSitePatterns PS00211 ABC transporters family signature. 135 149 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 ALX04_RS03240 c476c2dbb6f256a211621bdbebf0dffa 258 Gene3D G3DSA:1.10.287.70 115 255 1.4E-22 T 28-03-2018 ALX04_RS03240 c476c2dbb6f256a211621bdbebf0dffa 258 Pfam PF07885 Ion channel 135 207 1.3E-15 T 28-03-2018 IPR013099 Potassium channel domain ALX04_RS03240 c476c2dbb6f256a211621bdbebf0dffa 258 SUPERFAMILY SSF81324 12 207 7.46E-35 T 28-03-2018 ALX04_RS15530 e899ff67eab11e9a5e6ff3ae6094716d 145 SUPERFAMILY SSF82784 3 139 3.8E-29 T 28-03-2018 IPR003718 OsmC/Ohr family ALX04_RS15530 e899ff67eab11e9a5e6ff3ae6094716d 145 Gene3D G3DSA:3.30.300.20 1 143 1.1E-21 T 28-03-2018 IPR015946 K homology domain-like, alpha/beta ALX04_RS15530 e899ff67eab11e9a5e6ff3ae6094716d 145 Pfam PF02566 OsmC-like protein 36 139 2.1E-15 T 28-03-2018 IPR003718 OsmC/Ohr family ALX04_RS02190 71f098460a552129be6f0aa897cb971d 234 Pfam PF13731 WxL domain surface cell wall-binding 24 230 2.1E-40 T 28-03-2018 IPR027994 WxL domain ALX04_RS13745 4c1f385a89b0e5f10c345e8c483b0f52 337 Gene3D G3DSA:1.10.3720.10 62 334 2.7E-30 T 28-03-2018 ALX04_RS13745 4c1f385a89b0e5f10c345e8c483b0f52 337 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 157 326 4.1E-24 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 ALX04_RS13745 4c1f385a89b0e5f10c345e8c483b0f52 337 SUPERFAMILY SSF161098 136 318 7.98E-34 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 ALX04_RS11840 515f24197a7ddb0446229612bf065005 338 Gene3D G3DSA:3.60.60.10 2 333 5.8E-78 T 28-03-2018 ALX04_RS11840 515f24197a7ddb0446229612bf065005 338 SUPERFAMILY SSF56235 2 322 9.26E-95 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal ALX04_RS11840 515f24197a7ddb0446229612bf065005 338 Pfam PF02275 Linear amide C-N hydrolases, choloylglycine hydrolase family 2 309 5.0E-77 T 28-03-2018 IPR029132 Choloylglycine hydrolase/NAAA C-terminal ALX04_RS06150 4d26ba79b2737ee1ddd722aa92d9d285 279 SUPERFAMILY SSF53850 1 274 7.24E-67 T 28-03-2018 ALX04_RS06150 4d26ba79b2737ee1ddd722aa92d9d285 279 Gene3D G3DSA:3.40.190.10 5 171 2.0E-35 T 28-03-2018 ALX04_RS06150 4d26ba79b2737ee1ddd722aa92d9d285 279 Gene3D G3DSA:3.40.190.10 172 277 7.2E-16 T 28-03-2018 ALX04_RS06150 4d26ba79b2737ee1ddd722aa92d9d285 279 SMART SM00062 47 275 1.1E-60 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF ALX04_RS06150 4d26ba79b2737ee1ddd722aa92d9d285 279 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 48 274 1.4E-59 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF ALX04_RS00045 458986b4a2bc30f68820c8f231c1cd48 209 Gene3D G3DSA:3.40.50.360 2 209 3.3E-37 T 28-03-2018 IPR029039 Flavoprotein-like domain ALX04_RS00045 458986b4a2bc30f68820c8f231c1cd48 209 Pfam PF02525 Flavodoxin-like fold 2 204 2.8E-39 T 28-03-2018 IPR003680 Flavodoxin-like fold ALX04_RS00045 458986b4a2bc30f68820c8f231c1cd48 209 SUPERFAMILY SSF52218 1 209 3.99E-47 T 28-03-2018 IPR029039 Flavoprotein-like domain ALX04_RS00045 458986b4a2bc30f68820c8f231c1cd48 209 Hamap MF_01216 FMN-dependent NADH-azoreductase [azoR]. 2 206 25.703 T 28-03-2018 IPR023048 NADH-azoreductase, FMN-dependent GO:0016661|GO:0055114 ALX04_RS03135 b90f5ed5121a15f36404c29eb31c8f49 112 SUPERFAMILY SSF109797 14 102 1.15E-5 T 28-03-2018 ALX04_RS00620 477f494ea427041263af320d9fd270b7 108 Pfam PF01883 Iron-sulfur cluster assembly protein 11 82 3.1E-16 T 28-03-2018 IPR002744 MIP18 family-like ALX04_RS00620 477f494ea427041263af320d9fd270b7 108 Gene3D G3DSA:3.30.300.130 7 107 1.2E-24 T 28-03-2018 IPR034904 Fe-S cluster assembly domain ALX04_RS00620 477f494ea427041263af320d9fd270b7 108 SUPERFAMILY SSF117916 9 106 1.96E-28 T 28-03-2018 IPR034904 Fe-S cluster assembly domain ALX04_RS12505 6afaf7ff74731a9ff0fba5a5a923ce89 189 Pfam PF09819 ABC-type cobalt transport system, permease component 11 134 2.3E-40 T 28-03-2018 IPR017195 ABC-type thiamin-related transport system, permease component 1, predicted ALX04_RS12505 6afaf7ff74731a9ff0fba5a5a923ce89 189 PIRSF PIRSF037394 1 189 2.6E-68 T 28-03-2018 IPR017195 ABC-type thiamin-related transport system, permease component 1, predicted ALX04_RS04245 8a5e414fd256dd96dfeb74442ffcf225 367 Gene3D G3DSA:3.30.565.10 221 367 2.7E-10 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain ALX04_RS04245 8a5e414fd256dd96dfeb74442ffcf225 367 SUPERFAMILY SSF55874 275 365 2.17E-7 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain ALX04_RS04245 8a5e414fd256dd96dfeb74442ffcf225 367 Pfam PF07730 Histidine kinase 179 245 5.6E-20 T 28-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 ALX04_RS14275 b289fb936fd037e5fbed1a19c195d0b7 49 SUPERFAMILY SSF57829 4 49 9.77E-16 T 28-03-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 ALX04_RS14275 b289fb936fd037e5fbed1a19c195d0b7 49 Pfam PF00471 Ribosomal protein L33 4 49 2.1E-20 T 28-03-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 ALX04_RS14275 b289fb936fd037e5fbed1a19c195d0b7 49 TIGRFAM TIGR01023 rpmG_bact: ribosomal protein bL33 3 49 2.4E-16 T 28-03-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 ALX04_RS14275 b289fb936fd037e5fbed1a19c195d0b7 49 Hamap MF_00294 50S ribosomal protein L33 [rpmG]. 2 49 16.035 T 28-03-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 ALX04_RS05650 8aa13a5b92c719deb1d418721d856262 603 SUPERFAMILY SSF55486 58 601 2.69E-131 T 28-03-2018 ALX04_RS05650 8aa13a5b92c719deb1d418721d856262 603 Pfam PF08439 Oligopeptidase F 118 186 3.0E-18 T 28-03-2018 IPR013647 Oligopeptidase F, N-terminal domain ALX04_RS05650 8aa13a5b92c719deb1d418721d856262 603 Pfam PF01432 Peptidase family M3 207 587 1.3E-73 T 28-03-2018 IPR001567 Peptidase M3A/M3B catalytic domain GO:0004222|GO:0006508 ALX04_RS05650 8aa13a5b92c719deb1d418721d856262 603 Gene3D G3DSA:1.10.1370.10 84 599 7.2E-36 T 28-03-2018 ALX04_RS05650 8aa13a5b92c719deb1d418721d856262 603 TIGRFAM TIGR00181 pepF: oligoendopeptidase F 10 598 2.4E-185 T 28-03-2018 IPR004438 Peptidase M3B, oligoendopeptidase F GO:0004222|GO:0006508 ALX04_RS04215 2a73853270b299ffcf63bf7c284709f5 144 Pfam PF10012 Uncharacterized protein conserved in bacteria (DUF2255) 22 135 1.3E-40 T 28-03-2018 IPR016888 Uncharacterised conserved protein UCP028498 ALX04_RS04215 2a73853270b299ffcf63bf7c284709f5 144 PIRSF PIRSF028498 12 143 1.5E-66 T 28-03-2018 IPR016888 Uncharacterised conserved protein UCP028498 ALX04_RS15345 f495eca94d584b2bf4381b2462d24134 146 Pfam PF03780 Asp23 family, cell envelope-related function 11 116 1.7E-24 T 28-03-2018 IPR005531 Alkaline shock protein Asp23 ALX04_RS10375 d0e996d2c9c4a540500b52f5d53478b2 171 Pfam PF04892 VanZ like family 38 160 8.3E-16 T 28-03-2018 IPR006976 VanZ-like ALX04_RS07190 5f692e6ee80bd3a82736301c6ed03380 149 Gene3D G3DSA:3.10.180.10 30 149 3.3E-21 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase ALX04_RS07190 5f692e6ee80bd3a82736301c6ed03380 149 SUPERFAMILY SSF54593 26 145 3.71E-21 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase ALX04_RS07190 5f692e6ee80bd3a82736301c6ed03380 149 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 29 145 1.4E-10 T 28-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain ALX04_RS01085 8e5af6bbdda486b369a23d9319655827 280 TIGRFAM TIGR01214 rmlD: dTDP-4-dehydrorhamnose reductase 3 278 7.1E-85 T 28-03-2018 IPR005913 dTDP-4-dehydrorhamnose reductase family Reactome: R-HSA-156581|Reactome: R-HSA-5689880 ALX04_RS01085 8e5af6bbdda486b369a23d9319655827 280 Gene3D G3DSA:3.40.50.720 2 198 7.4E-31 T 28-03-2018 ALX04_RS01085 8e5af6bbdda486b369a23d9319655827 280 SUPERFAMILY SSF51735 1 279 1.59E-88 T 28-03-2018 IPR016040 NAD(P)-binding domain ALX04_RS01085 8e5af6bbdda486b369a23d9319655827 280 Gene3D G3DSA:3.90.25.10 199 266 3.5E-20 T 28-03-2018 ALX04_RS01085 8e5af6bbdda486b369a23d9319655827 280 Pfam PF04321 RmlD substrate binding domain 3 279 2.2E-104 T 28-03-2018 IPR029903 RmlD-like substrate binding domain Reactome: R-HSA-156581|Reactome: R-HSA-5689880 ALX04_RS04315 56f91f016510fdccfee154ac4547443b 297 ProSitePatterns PS00211 ABC transporters family signature. 128 142 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 ALX04_RS04315 56f91f016510fdccfee154ac4547443b 297 Pfam PF00005 ABC transporter 18 155 7.5E-19 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 ALX04_RS04315 56f91f016510fdccfee154ac4547443b 297 SUPERFAMILY SSF52540 3 219 4.96E-43 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase ALX04_RS04315 56f91f016510fdccfee154ac4547443b 297 Gene3D G3DSA:3.40.50.300 1 228 1.6E-42 T 28-03-2018 ALX04_RS04315 56f91f016510fdccfee154ac4547443b 297 SMART SM00382 27 249 4.8E-10 T 28-03-2018 IPR003593 AAA+ ATPase domain ALX04_RS10205 273a5e80e1786d46abcd19753c933eb2 485 SUPERFAMILY SSF56024 86 315 3.08E-54 T 28-03-2018 ALX04_RS10205 273a5e80e1786d46abcd19753c933eb2 485 SMART SM00155 220 247 0.0019 T 28-03-2018 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 ALX04_RS10205 273a5e80e1786d46abcd19753c933eb2 485 SMART SM00155 398 425 7.5E-7 T 28-03-2018 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 ALX04_RS10205 273a5e80e1786d46abcd19753c933eb2 485 Hamap MF_01916 Cardiolipin synthase. 12 485 43.398 T 28-03-2018 IPR030874 Cardiolipin synthase, Firmicutes-type GO:0008808|GO:0032049 ALX04_RS10205 273a5e80e1786d46abcd19753c933eb2 485 Pfam PF13091 PLD-like domain 326 451 1.6E-31 T 28-03-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 ALX04_RS10205 273a5e80e1786d46abcd19753c933eb2 485 Pfam PF13091 PLD-like domain 139 280 5.9E-12 T 28-03-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 ALX04_RS10205 273a5e80e1786d46abcd19753c933eb2 485 Gene3D G3DSA:3.30.870.10 289 470 4.6E-34 T 28-03-2018 ALX04_RS10205 273a5e80e1786d46abcd19753c933eb2 485 Gene3D G3DSA:3.30.870.10 64 288 2.4E-35 T 28-03-2018 ALX04_RS10205 273a5e80e1786d46abcd19753c933eb2 485 Pfam PF13396 Phospholipase_D-nuclease N-terminal 17 60 1.5E-10 T 28-03-2018 IPR027379 Cardiolipin synthase N-terminal ALX04_RS10205 273a5e80e1786d46abcd19753c933eb2 485 TIGRFAM TIGR04265 bac_cardiolipin: cardiolipin synthase 10 485 5.2E-166 T 28-03-2018 IPR022924 Cardiolipin synthase GO:0008808|GO:0016780|GO:0032049 ALX04_RS10205 273a5e80e1786d46abcd19753c933eb2 485 SUPERFAMILY SSF56024 272 472 6.73E-55 T 28-03-2018 ALX04_RS13560 ea1fd63faaa337bb6308770113814d05 232 SMART SM00382 30 217 1.4E-10 T 28-03-2018 IPR003593 AAA+ ATPase domain ALX04_RS13560 ea1fd63faaa337bb6308770113814d05 232 SUPERFAMILY SSF52540 1 211 1.56E-48 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase ALX04_RS13560 ea1fd63faaa337bb6308770113814d05 232 Pfam PF00005 ABC transporter 22 161 9.7E-26 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 ALX04_RS13560 ea1fd63faaa337bb6308770113814d05 232 Gene3D G3DSA:3.40.50.300 1 231 1.0E-49 T 28-03-2018 ALX04_RS08670 792a137f038af2b0171f75520622b7d8 444 Gene3D G3DSA:1.20.1250.20 249 443 1.0E-21 T 28-03-2018 ALX04_RS08670 792a137f038af2b0171f75520622b7d8 444 Pfam PF07690 Major Facilitator Superfamily 15 401 9.2E-54 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 ALX04_RS08670 792a137f038af2b0171f75520622b7d8 444 SUPERFAMILY SSF103473 238 439 3.79E-61 T 28-03-2018 IPR020846 Major facilitator superfamily domain ALX04_RS08670 792a137f038af2b0171f75520622b7d8 444 SUPERFAMILY SSF103473 8 194 3.79E-61 T 28-03-2018 IPR020846 Major facilitator superfamily domain ALX04_RS08670 792a137f038af2b0171f75520622b7d8 444 Gene3D G3DSA:1.20.1250.20 9 197 3.9E-33 T 28-03-2018 ALX04_RS00280 80ddab27147aaef44e880fd261d1419c 257 Pfam PF02557 D-alanyl-D-alanine carboxypeptidase 88 229 3.4E-34 T 28-03-2018 IPR003709 Peptidase M15B GO:0006508|GO:0008233 ALX04_RS00280 80ddab27147aaef44e880fd261d1419c 257 Gene3D G3DSA:3.30.1380.10 53 241 1.2E-30 T 28-03-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 ALX04_RS00280 80ddab27147aaef44e880fd261d1419c 257 SUPERFAMILY SSF55166 79 237 8.37E-28 T 28-03-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 ALX04_RS12535 12378df9c5b2425374d03143aa44c790 237 Hamap MF_01241 Glucosamine-6-phosphate deaminase [nagB]. 1 233 40.319 T 28-03-2018 IPR004547 Glucosamine-6-phosphate isomerase GO:0004342|GO:0006044 KEGG: 00520+3.5.99.6|MetaCyc: PWY-5514|MetaCyc: PWY-6855|MetaCyc: PWY-6906|Reactome: R-HSA-70326 ALX04_RS12535 12378df9c5b2425374d03143aa44c790 237 Pfam PF01182 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase 28 220 7.6E-15 T 28-03-2018 IPR006148 Glucosamine/galactosamine-6-phosphate isomerase GO:0005975 KEGG: 00520+3.5.99.6|MetaCyc: PWY-5514|MetaCyc: PWY-6855|MetaCyc: PWY-6906 ALX04_RS12535 12378df9c5b2425374d03143aa44c790 237 Gene3D G3DSA:3.40.50.1360 1 237 2.8E-64 T 28-03-2018 ALX04_RS12535 12378df9c5b2425374d03143aa44c790 237 SUPERFAMILY SSF100950 1 236 2.56E-82 T 28-03-2018 ALX04_RS12535 12378df9c5b2425374d03143aa44c790 237 ProSitePatterns PS01161 Glucosamine/galactosamine-6-phosphate isomerases signature. 112 130 - T 28-03-2018 IPR018321 Glucosamine-6-phosphate isomerase, conserved site GO:0004342|GO:0006044 KEGG: 00520+3.5.99.6|MetaCyc: PWY-5514|MetaCyc: PWY-6855|MetaCyc: PWY-6906|Reactome: R-HSA-70326 ALX04_RS06670 927e89811b4c59988d2d8be269feec76 204 Gene3D G3DSA:1.20.5.730 15 115 2.7E-5 T 28-03-2018 ALX04_RS06670 927e89811b4c59988d2d8be269feec76 204 Pfam PF06810 Phage minor structural protein GP20 15 153 1.2E-37 T 28-03-2018 IPR009636 Capsid assembly scaffolding protein GO:0019069|GO:0046806 ALX04_RS11695 d1481cccb4c626d0bef10696c327fc26 149 SUPERFAMILY SSF50475 5 129 1.27E-16 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 ALX04_RS11695 d1481cccb4c626d0bef10696c327fc26 149 Gene3D G3DSA:2.30.110.10 1 133 6.5E-16 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 ALX04_RS11695 d1481cccb4c626d0bef10696c327fc26 149 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 7 89 2.4E-10 T 28-03-2018 IPR011576 Pyridoxamine 5'-phosphate oxidase, putative KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 ALX04_RS15080 a1d46ae03464ed3d91f8ba54bb2a5bdd 272 Pfam PF08543 Phosphomethylpyrimidine kinase 69 251 3.6E-22 T 28-03-2018 IPR013749 Pyridoxamine kinase/Phosphomethylpyrimidine kinase Reactome: R-HSA-6798695|Reactome: R-HSA-964975 ALX04_RS15080 a1d46ae03464ed3d91f8ba54bb2a5bdd 272 SUPERFAMILY SSF53613 4 249 5.24E-40 T 28-03-2018 IPR029056 Ribokinase-like ALX04_RS15080 a1d46ae03464ed3d91f8ba54bb2a5bdd 272 Gene3D G3DSA:3.40.1190.20 2 271 7.2E-37 T 28-03-2018 IPR029056 Ribokinase-like ALX04_RS11185 b07b3581a3c51823d9a3f5ef71b9620c 282 SUPERFAMILY SSF50151 3 50 2.22E-13 T 28-03-2018 IPR004341 CAT RNA-binding domain GO:0003723 ALX04_RS11185 b07b3581a3c51823d9a3f5ef71b9620c 282 Gene3D G3DSA:1.10.1790.10 65 163 6.0E-17 T 28-03-2018 IPR011608 PRD domain GO:0006355 ALX04_RS11185 b07b3581a3c51823d9a3f5ef71b9620c 282 Pfam PF03123 CAT RNA binding domain 4 52 2.3E-15 T 28-03-2018 IPR004341 CAT RNA-binding domain GO:0003723 ALX04_RS11185 b07b3581a3c51823d9a3f5ef71b9620c 282 SUPERFAMILY SSF63520 171 275 2.49E-20 T 28-03-2018 IPR011608 PRD domain GO:0006355 ALX04_RS11185 b07b3581a3c51823d9a3f5ef71b9620c 282 Gene3D G3DSA:2.30.24.10 1 64 1.4E-17 T 28-03-2018 IPR004341 CAT RNA-binding domain GO:0003723 ALX04_RS11185 b07b3581a3c51823d9a3f5ef71b9620c 282 Pfam PF00874 PRD domain 182 272 7.6E-14 T 28-03-2018 IPR011608 PRD domain GO:0006355 ALX04_RS11185 b07b3581a3c51823d9a3f5ef71b9620c 282 Pfam PF00874 PRD domain 74 162 2.4E-16 T 28-03-2018 IPR011608 PRD domain GO:0006355 ALX04_RS11185 b07b3581a3c51823d9a3f5ef71b9620c 282 SMART SM01061 1 61 2.9E-17 T 28-03-2018 IPR004341 CAT RNA-binding domain GO:0003723 ALX04_RS11185 b07b3581a3c51823d9a3f5ef71b9620c 282 Gene3D G3DSA:1.10.1790.10 164 279 8.7E-19 T 28-03-2018 IPR011608 PRD domain GO:0006355 ALX04_RS11185 b07b3581a3c51823d9a3f5ef71b9620c 282 SUPERFAMILY SSF63520 71 162 2.09E-19 T 28-03-2018 IPR011608 PRD domain GO:0006355 ALX04_RS13515 b3e9de3c12f846750ff6f18e8eaf387a 129 Pfam PF00293 NUDIX domain 11 113 4.7E-13 T 28-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 ALX04_RS13515 b3e9de3c12f846750ff6f18e8eaf387a 129 SUPERFAMILY SSF55811 10 111 6.23E-22 T 28-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 ALX04_RS13515 b3e9de3c12f846750ff6f18e8eaf387a 129 Gene3D G3DSA:3.90.79.10 4 128 2.7E-17 T 28-03-2018 ALX04_RS10895 4cb8517fee7d93b00e5b06dff158046e 337 Pfam PF11797 Protein of unknown function C-terminal (DUF3324) 160 296 2.9E-49 T 28-03-2018 IPR021759 Domain of unknown function DUF3324, C-terminal ALX04_RS10895 4cb8517fee7d93b00e5b06dff158046e 337 Pfam PF06030 Bacterial protein of unknown function (DUF916) 30 148 1.9E-39 T 28-03-2018 IPR010317 Protein of unknown function DUF916, cell surface putative ALX04_RS10895 4cb8517fee7d93b00e5b06dff158046e 337 Gene3D G3DSA:2.60.40.1710 38 163 6.7E-13 T 28-03-2018 ALX04_RS11050 f5fc3672e5258ff006bbdb6d592187e7 340 Gene3D G3DSA:3.20.20.100 14 331 1.6E-82 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain ALX04_RS11050 f5fc3672e5258ff006bbdb6d592187e7 340 Pfam PF00248 Aldo/keto reductase family 27 327 1.4E-64 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain ALX04_RS11050 f5fc3672e5258ff006bbdb6d592187e7 340 SUPERFAMILY SSF51430 12 331 1.96E-86 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain ALX04_RS06415 d1ce6331fa1097f7d313f944844a1311 314 Gene3D G3DSA:1.10.287.80 267 308 3.8E-12 T 28-03-2018 ALX04_RS06415 d1ce6331fa1097f7d313f944844a1311 314 Pfam PF00231 ATP synthase 4 310 9.0E-85 T 28-03-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 ALX04_RS06415 d1ce6331fa1097f7d313f944844a1311 314 PRINTS PR00126 ATP synthase gamma subunit signature 88 107 1.5E-30 T 28-03-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 ALX04_RS06415 d1ce6331fa1097f7d313f944844a1311 314 PRINTS PR00126 ATP synthase gamma subunit signature 181 198 1.5E-30 T 28-03-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 ALX04_RS06415 d1ce6331fa1097f7d313f944844a1311 314 PRINTS PR00126 ATP synthase gamma subunit signature 291 312 1.5E-30 T 28-03-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 ALX04_RS06415 d1ce6331fa1097f7d313f944844a1311 314 PRINTS PR00126 ATP synthase gamma subunit signature 260 279 1.5E-30 T 28-03-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 ALX04_RS06415 d1ce6331fa1097f7d313f944844a1311 314 TIGRFAM TIGR01146 ATPsyn_F1gamma: ATP synthase F1, gamma subunit 4 311 3.1E-88 T 28-03-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 ALX04_RS06415 d1ce6331fa1097f7d313f944844a1311 314 Hamap MF_00815 ATP synthase gamma chain [atpG]. 2 313 32.089 T 28-03-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 ALX04_RS06415 d1ce6331fa1097f7d313f944844a1311 314 SUPERFAMILY SSF52943 4 310 1.27E-79 T 28-03-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 ALX04_RS06415 d1ce6331fa1097f7d313f944844a1311 314 Gene3D G3DSA:3.40.1380.10 28 266 6.7E-63 T 28-03-2018 ALX04_RS06725 5da131860a839c8205080050382bad98 149 TIGRFAM TIGR01637 phage_arpU: phage transcriptional regulator, ArpU family 10 136 8.7E-18 T 28-03-2018 IPR006524 Transcription activator, ArpU family ALX04_RS05055 329041170ba45f6e61e32c47ab6f4c02 194 SUPERFAMILY SSF46785 3 131 2.72E-8 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS05055 329041170ba45f6e61e32c47ab6f4c02 194 Pfam PF12840 Helix-turn-helix domain 7 63 1.2E-8 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS05055 329041170ba45f6e61e32c47ab6f4c02 194 Gene3D G3DSA:1.10.10.10 1 137 3.3E-5 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS03495 0552ff300f0923730c4c7d4650490395 128 Gene3D G3DSA:3.30.420.10 1 128 6.8E-16 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 ALX04_RS03495 0552ff300f0923730c4c7d4650490395 128 SUPERFAMILY SSF53098 2 125 9.61E-19 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 ALX04_RS03495 0552ff300f0923730c4c7d4650490395 128 Pfam PF00075 RNase H 2 82 5.7E-10 T 28-03-2018 IPR002156 Ribonuclease H domain GO:0003676|GO:0004523 ALX04_RS10050 9f5a9b910f29be3616e23243c5d08d8e 106 SUPERFAMILY SSF52794 3 98 1.26E-30 T 28-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 ALX04_RS10050 9f5a9b910f29be3616e23243c5d08d8e 106 Gene3D G3DSA:3.40.50.2300 2 101 1.7E-32 T 28-03-2018 ALX04_RS10050 9f5a9b910f29be3616e23243c5d08d8e 106 TIGRFAM TIGR00829 FRU: PTS system, Fru family, IIB component 4 88 9.3E-27 T 28-03-2018 IPR003353 Phosphotransferase system, fructose-specific IIB subunit GO:0009401|GO:0022877 KEGG: 00051+2.7.1.202|KEGG: 00230+2.7.1.20|MetaCyc: PWY-6619 ALX04_RS10050 9f5a9b910f29be3616e23243c5d08d8e 106 Pfam PF02302 PTS system, Lactose/Cellobiose specific IIB subunit 5 96 2.2E-17 T 28-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 ALX04_RS03010 253a4f62a553e9ab757e16568d78fa0f 270 Pfam PF00106 short chain dehydrogenase 3 180 2.2E-47 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR ALX04_RS03010 253a4f62a553e9ab757e16568d78fa0f 270 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 144 163 9.8E-25 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR ALX04_RS03010 253a4f62a553e9ab757e16568d78fa0f 270 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 71 82 9.8E-25 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR ALX04_RS03010 253a4f62a553e9ab757e16568d78fa0f 270 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 118 134 9.8E-25 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR ALX04_RS03010 253a4f62a553e9ab757e16568d78fa0f 270 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 3 20 9.8E-25 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR ALX04_RS03010 253a4f62a553e9ab757e16568d78fa0f 270 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 165 182 9.8E-25 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR ALX04_RS03010 253a4f62a553e9ab757e16568d78fa0f 270 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 71 82 2.7E-10 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR ALX04_RS03010 253a4f62a553e9ab757e16568d78fa0f 270 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 124 132 2.7E-10 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR ALX04_RS03010 253a4f62a553e9ab757e16568d78fa0f 270 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 144 163 2.7E-10 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR ALX04_RS03010 253a4f62a553e9ab757e16568d78fa0f 270 SUPERFAMILY SSF51735 3 246 1.18E-63 T 28-03-2018 IPR016040 NAD(P)-binding domain ALX04_RS03010 253a4f62a553e9ab757e16568d78fa0f 270 Gene3D G3DSA:3.40.50.720 2 261 6.5E-63 T 28-03-2018 ALX04_RS12450 48d4fb4c0781cf08555588bc8d6db9eb 329 SUPERFAMILY SSF51430 14 328 6.42E-85 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain ALX04_RS12450 48d4fb4c0781cf08555588bc8d6db9eb 329 Pfam PF00248 Aldo/keto reductase family 28 328 5.0E-68 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain ALX04_RS12450 48d4fb4c0781cf08555588bc8d6db9eb 329 PRINTS PR01577 KCNAB voltage-gated K+ channel beta subunit family signature 126 136 4.8E-5 T 28-03-2018 IPR005399 Potassium channel, voltage-dependent, beta subunit, KCNAB-related Reactome: R-HSA-1296072 ALX04_RS12450 48d4fb4c0781cf08555588bc8d6db9eb 329 PRINTS PR01577 KCNAB voltage-gated K+ channel beta subunit family signature 270 282 4.8E-5 T 28-03-2018 IPR005399 Potassium channel, voltage-dependent, beta subunit, KCNAB-related Reactome: R-HSA-1296072 ALX04_RS12450 48d4fb4c0781cf08555588bc8d6db9eb 329 PRINTS PR01577 KCNAB voltage-gated K+ channel beta subunit family signature 283 296 4.8E-5 T 28-03-2018 IPR005399 Potassium channel, voltage-dependent, beta subunit, KCNAB-related Reactome: R-HSA-1296072 ALX04_RS12450 48d4fb4c0781cf08555588bc8d6db9eb 329 Gene3D G3DSA:3.20.20.100 15 329 2.3E-82 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain ALX04_RS07990 40739446da9016dcc1466ca13bc96f0b 123 SUPERFAMILY SSF46785 4 88 2.25E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS07990 40739446da9016dcc1466ca13bc96f0b 123 Gene3D G3DSA:1.10.287.100 77 118 1.4E-16 T 28-03-2018 ALX04_RS07990 40739446da9016dcc1466ca13bc96f0b 123 Pfam PF00392 Bacterial regulatory proteins, gntR family 12 74 8.5E-12 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 ALX04_RS07990 40739446da9016dcc1466ca13bc96f0b 123 SMART SM00345 15 74 6.5E-9 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 ALX04_RS07990 40739446da9016dcc1466ca13bc96f0b 123 Gene3D G3DSA:1.10.10.10 2 76 2.3E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS11555 4dc8ad5659b769875717c70e97da3190 277 TIGRFAM TIGR03592 yidC_oxa1_cterm: membrane protein insertase, YidC/Oxa1 family 58 241 6.6E-59 T 28-03-2018 IPR028055 Membrane insertase YidC/Oxa1, C-terminal ALX04_RS11555 4dc8ad5659b769875717c70e97da3190 277 Pfam PF02096 60Kd inner membrane protein 59 241 7.3E-52 T 28-03-2018 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 ALX04_RS11555 4dc8ad5659b769875717c70e97da3190 277 PRINTS PR00701 60kDa inner membrane protein signature 124 147 8.4E-10 T 28-03-2018 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 ALX04_RS11555 4dc8ad5659b769875717c70e97da3190 277 PRINTS PR00701 60kDa inner membrane protein signature 208 231 8.4E-10 T 28-03-2018 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 ALX04_RS11555 4dc8ad5659b769875717c70e97da3190 277 Hamap MF_01811 Membrane protein insertase YidC [yidC]. 2 245 32.543 T 28-03-2018 IPR023060 Membrane insertase YidC/YidC1/YidC2, Firmicutes ALX04_RS11555 4dc8ad5659b769875717c70e97da3190 277 Gene3D G3DSA:3.40.190.10 2 52 0.0019 T 28-03-2018 ALX04_RS06915 8635b6140a83be20c41848b1188441f9 567 Pfam PF03354 Phage Terminase 69 539 1.9E-96 T 28-03-2018 IPR005021 Terminase large subunit, Lambdalikevirus-type ALX04_RS05645 b0b9c2e6f84a22234d0978fa6b85bacf 211 Pfam PF13743 Thioredoxin 5 178 1.5E-48 T 28-03-2018 ALX04_RS05645 b0b9c2e6f84a22234d0978fa6b85bacf 211 SUPERFAMILY SSF52833 73 158 4.31E-5 T 28-03-2018 IPR012336 Thioredoxin-like fold ALX04_RS05645 b0b9c2e6f84a22234d0978fa6b85bacf 211 Gene3D G3DSA:3.40.30.10 1 176 2.4E-8 T 28-03-2018 ALX04_RS07150 ce8c71f1bee50cb6e049a443d9b3e612 297 Pfam PF00877 NlpC/P60 family 190 295 2.2E-22 T 28-03-2018 IPR000064 Endopeptidase, NLPC/P60 domain ALX04_RS07150 ce8c71f1bee50cb6e049a443d9b3e612 297 Gene3D G3DSA:2.30.30.40 39 104 4.2E-4 T 28-03-2018 ALX04_RS07150 ce8c71f1bee50cb6e049a443d9b3e612 297 SUPERFAMILY SSF54001 177 296 3.92E-35 T 28-03-2018 ALX04_RS07150 ce8c71f1bee50cb6e049a443d9b3e612 297 Gene3D G3DSA:3.90.1720.10 173 297 6.9E-31 T 28-03-2018 ALX04_RS05135 bd3a75c3898d975b0c9ee555c427b85f 363 Pfam PF13439 Glycosyltransferase Family 4 12 177 6.4E-22 T 28-03-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193 ALX04_RS05135 bd3a75c3898d975b0c9ee555c427b85f 363 Gene3D G3DSA:3.40.50.2000 2 191 1.3E-17 T 28-03-2018 ALX04_RS05135 bd3a75c3898d975b0c9ee555c427b85f 363 Gene3D G3DSA:3.40.50.2000 192 353 1.3E-35 T 28-03-2018 ALX04_RS05135 bd3a75c3898d975b0c9ee555c427b85f 363 SUPERFAMILY SSF53756 3 362 1.19E-67 T 28-03-2018 ALX04_RS05135 bd3a75c3898d975b0c9ee555c427b85f 363 Pfam PF00534 Glycosyl transferases group 1 183 329 3.1E-28 T 28-03-2018 IPR001296 Glycosyl transferase, family 1 ALX04_RS08390 ca422000dedba8ab7abc65e1f99e6f0b 308 Pfam PF03547 Membrane transport protein 160 300 1.2E-8 T 28-03-2018 IPR004776 Membrane transport protein GO:0016021|GO:0055085 ALX04_RS08390 ca422000dedba8ab7abc65e1f99e6f0b 308 Pfam PF03547 Membrane transport protein 9 152 5.7E-13 T 28-03-2018 IPR004776 Membrane transport protein GO:0016021|GO:0055085 ALX04_RS11265 9bad28ee3a5ae7246465fc41d50cefac 423 PIRSF PIRSF006304 4 423 1.2E-153 T 28-03-2018 IPR013853 Galactitol permease IIC component GO:0015577|GO:0015796 ALX04_RS11265 9bad28ee3a5ae7246465fc41d50cefac 423 Pfam PF03611 PTS system sugar-specific permease component 11 391 2.1E-82 T 28-03-2018 IPR004703 Phosphotransferase system, sugar-specific permease component GO:0009401|GO:0016021 ALX04_RS05045 c0fb39c5c15db002bb6f0066eb8ea6c7 115 SUPERFAMILY SSF117782 5 104 4.45E-33 T 28-03-2018 IPR002765 Uncharacterised protein family UPF0145 ALX04_RS05045 c0fb39c5c15db002bb6f0066eb8ea6c7 115 Hamap MF_00338 UPF0145 protein YbjQ [ybjQ]. 4 105 23.052 T 28-03-2018 IPR002765 Uncharacterised protein family UPF0145 ALX04_RS05045 c0fb39c5c15db002bb6f0066eb8ea6c7 115 Gene3D G3DSA:3.30.110.70 4 105 8.0E-30 T 28-03-2018 IPR035439 Uncharacterised protein family UPF0145/C2CD5 Reactome: R-HSA-1445148 ALX04_RS05045 c0fb39c5c15db002bb6f0066eb8ea6c7 115 Pfam PF01906 Putative heavy-metal-binding 5 104 1.2E-35 T 28-03-2018 IPR002765 Uncharacterised protein family UPF0145 ALX04_RS01620 40724d4391c56d218c082089e6f5f09e 502 Gene3D G3DSA:3.40.50.2000 310 485 1.3E-29 T 28-03-2018 ALX04_RS01620 40724d4391c56d218c082089e6f5f09e 502 SUPERFAMILY SSF53756 274 498 1.62E-38 T 28-03-2018 ALX04_RS01620 40724d4391c56d218c082089e6f5f09e 502 Pfam PF00534 Glycosyl transferases group 1 323 480 8.3E-28 T 28-03-2018 IPR001296 Glycosyl transferase, family 1 ALX04_RS10180 34e108bc28c7504a59fb76c888c84fd0 109 Gene3D G3DSA:1.20.1440.50 4 92 3.8E-14 T 28-03-2018 IPR023130 Ta0600-like domain ALX04_RS10180 34e108bc28c7504a59fb76c888c84fd0 109 SUPERFAMILY SSF109797 1 80 5.23E-5 T 28-03-2018 ALX04_RS10180 34e108bc28c7504a59fb76c888c84fd0 109 Pfam PF08951 Enterocin A Immunity 8 76 1.9E-12 T 28-03-2018 IPR015046 Enterocin A Immunity ALX04_RS07235 514c4efaab2af2c4fb4f32c897fbf489 332 Pfam PF04392 ABC transporter substrate binding protein 35 325 4.2E-85 T 28-03-2018 IPR007487 ABC transporter, substrate-binding protein ALX04_RS07235 514c4efaab2af2c4fb4f32c897fbf489 332 Gene3D G3DSA:3.40.50.2300 11 158 3.7E-19 T 28-03-2018 ALX04_RS07235 514c4efaab2af2c4fb4f32c897fbf489 332 SUPERFAMILY SSF53822 43 301 1.45E-17 T 28-03-2018 IPR028082 Periplasmic binding protein-like I ALX04_RS07235 514c4efaab2af2c4fb4f32c897fbf489 332 Gene3D G3DSA:3.40.50.2300 159 294 4.4E-22 T 28-03-2018 ALX04_RS01145 f6157fb98cbfe0aac78aa742372abb3a 478 Pfam PF14667 Polysaccharide biosynthesis C-terminal domain 330 464 3.5E-7 T 28-03-2018 IPR029303 Polysaccharide biosynthesis protein, C-terminal domain ALX04_RS01145 f6157fb98cbfe0aac78aa742372abb3a 478 Pfam PF01943 Polysaccharide biosynthesis protein 13 273 1.1E-20 T 28-03-2018 IPR002797 Polysaccharide biosynthesis protein GO:0016020 ALX04_RS12395 5fc369159a64cecab5f05fc49447eaf3 466 Pfam PF03553 Na+/H+ antiporter family 162 455 3.3E-45 T 28-03-2018 IPR018461 Na+/H+ antiporter, NhaC-like, C-terminal GO:0016021 ALX04_RS12395 5fc369159a64cecab5f05fc49447eaf3 466 TIGRFAM TIGR00931 antiport_nhaC: Na+/H+ antiporter NhaC 12 458 4.5E-120 T 28-03-2018 IPR004770 Na+/H+ antiporter NhaC GO:0015297|GO:0016021 ALX04_RS13800 fd347c10cf1eee723f8bc1db8e900578 464 SUPERFAMILY SSF143985 215 332 6.15E-36 T 28-03-2018 ALX04_RS13800 fd347c10cf1eee723f8bc1db8e900578 464 SUPERFAMILY SSF141523 337 463 1.7E-34 T 28-03-2018 ALX04_RS13800 fd347c10cf1eee723f8bc1db8e900578 464 Gene3D G3DSA:2.40.440.10 339 464 1.7E-29 T 28-03-2018 ALX04_RS13800 fd347c10cf1eee723f8bc1db8e900578 464 Pfam PF12229 Putative peptidoglycan binding domain 205 319 1.2E-20 T 28-03-2018 IPR022029 Putative peptidoglycan binding domain ALX04_RS13800 fd347c10cf1eee723f8bc1db8e900578 464 Pfam PF12229 Putative peptidoglycan binding domain 78 191 3.2E-6 T 28-03-2018 IPR022029 Putative peptidoglycan binding domain ALX04_RS13800 fd347c10cf1eee723f8bc1db8e900578 464 Pfam PF03734 L,D-transpeptidase catalytic domain 340 463 2.0E-19 T 28-03-2018 IPR005490 L,D-transpeptidase catalytic domain GO:0016740 ALX04_RS12905 10a6df87bfd0672df3ad36e89488a6b6 124 Pfam PF01597 Glycine cleavage H-protein 24 123 1.2E-12 T 28-03-2018 IPR033753 Glycine cleavage system H-protein/Simiate ALX04_RS12905 10a6df87bfd0672df3ad36e89488a6b6 124 SUPERFAMILY SSF51230 30 123 5.02E-17 T 28-03-2018 IPR011053 Single hybrid motif ALX04_RS12905 10a6df87bfd0672df3ad36e89488a6b6 124 Gene3D G3DSA:2.40.50.100 17 124 4.4E-15 T 28-03-2018 ALX04_RS09195 cc704721d14415f01f9979d522d6b33a 278 Gene3D G3DSA:3.60.21.10 2 258 7.8E-30 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like ALX04_RS09195 cc704721d14415f01f9979d522d6b33a 278 SUPERFAMILY SSF56300 1 240 4.88E-49 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like ALX04_RS09195 cc704721d14415f01f9979d522d6b33a 278 Pfam PF12850 Calcineurin-like phosphoesterase superfamily domain 4 207 2.7E-18 T 28-03-2018 IPR024654 Calcineurin-like phosphoesterase domain, lpxH type Reactome: R-HSA-3238698 ALX04_RS09195 cc704721d14415f01f9979d522d6b33a 278 PIRSF PIRSF000883 3 251 1.4E-77 T 28-03-2018 IPR011152 Phosphoesterase MJ0912 ALX04_RS08520 7c0123516406eb3d549e8c3dde35bd3d 216 SMART SM00478 39 187 1.3E-44 T 28-03-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 ALX04_RS08520 7c0123516406eb3d549e8c3dde35bd3d 216 PIRSF PIRSF001435 1 214 1.8E-42 T 28-03-2018 ALX04_RS08520 7c0123516406eb3d549e8c3dde35bd3d 216 Gene3D G3DSA:1.10.340.30 23 118 7.9E-23 T 28-03-2018 ALX04_RS08520 7c0123516406eb3d549e8c3dde35bd3d 216 Hamap MF_00942 Endonuclease III [nth]. 1 211 31.526 T 28-03-2018 IPR005759 Endonuclease III GO:0003906|GO:0006284 ALX04_RS08520 7c0123516406eb3d549e8c3dde35bd3d 216 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 35 168 5.9E-24 T 28-03-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 ALX04_RS08520 7c0123516406eb3d549e8c3dde35bd3d 216 SUPERFAMILY SSF48150 3 207 2.51E-53 T 28-03-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 ALX04_RS08520 7c0123516406eb3d549e8c3dde35bd3d 216 Gene3D G3DSA:1.10.1670.10 119 216 1.3E-20 T 28-03-2018 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 ALX04_RS05110 34bc5f5bcbeefcb1221b5d9d0f70cf26 440 Gene3D G3DSA:3.60.21.10 24 350 2.6E-29 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like ALX04_RS05110 34bc5f5bcbeefcb1221b5d9d0f70cf26 440 SUPERFAMILY SSF56300 39 319 6.87E-31 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like ALX04_RS05110 34bc5f5bcbeefcb1221b5d9d0f70cf26 440 PIRSF PIRSF034890 1 440 2.3E-247 T 28-03-2018 IPR012365 Phosphoesterase, lmo2642-related ALX04_RS05110 34bc5f5bcbeefcb1221b5d9d0f70cf26 440 Pfam PF00149 Calcineurin-like phosphoesterase 42 282 6.7E-16 T 28-03-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 ALX04_RS05915 fbb65d71966fdb0713e7231da948f4cb 290 Gene3D G3DSA:3.20.20.150 15 280 9.9E-23 T 28-03-2018 ALX04_RS05915 fbb65d71966fdb0713e7231da948f4cb 290 SUPERFAMILY SSF51658 69 275 7.77E-17 T 28-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain ALX04_RS05915 fbb65d71966fdb0713e7231da948f4cb 290 Pfam PF01261 Xylose isomerase-like TIM barrel 37 237 2.2E-8 T 28-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain ALX04_RS14970 4be2d0965f90f5d91fa21b1e0f588975 140 SUPERFAMILY SSF52833 3 130 9.69E-34 T 28-03-2018 IPR012336 Thioredoxin-like fold ALX04_RS14970 4be2d0965f90f5d91fa21b1e0f588975 140 Gene3D G3DSA:3.40.30.10 1 140 6.6E-34 T 28-03-2018 ALX04_RS14970 4be2d0965f90f5d91fa21b1e0f588975 140 Pfam PF03960 ArsC family 11 114 1.9E-21 T 28-03-2018 IPR006660 Arsenate reductase-like ALX04_RS14970 4be2d0965f90f5d91fa21b1e0f588975 140 TIGRFAM TIGR01617 arsC_related: transcriptional regulator, Spx/MgsR family 4 115 1.9E-33 T 28-03-2018 IPR006504 Transcriptional regulator Spx/MgsR ALX04_RS12175 1756f994c75b6629cfe2b7987ecef5c2 564 Gene3D G3DSA:3.50.50.60 2 542 2.4E-6 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ALX04_RS12175 1756f994c75b6629cfe2b7987ecef5c2 564 Pfam PF06100 MCRA family 4 532 1.1E-174 T 28-03-2018 IPR010354 Oleate hydratase GO:0006631|GO:0050151|GO:0071949 ALX04_RS12175 1756f994c75b6629cfe2b7987ecef5c2 564 SUPERFAMILY SSF51905 179 297 9.72E-9 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ALX04_RS12175 1756f994c75b6629cfe2b7987ecef5c2 564 SUPERFAMILY SSF51905 6 138 9.72E-9 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ALX04_RS13505 70737d83daa7ce0938560d332fd3416e 234 Pfam PF02146 Sir2 family 22 190 3.0E-37 T 28-03-2018 IPR003000 Sirtuin family GO:0070403 ALX04_RS13505 70737d83daa7ce0938560d332fd3416e 234 Gene3D G3DSA:3.40.50.1220 1 233 9.7E-49 T 28-03-2018 IPR029035 DHS-like NAD/FAD-binding domain ALX04_RS13505 70737d83daa7ce0938560d332fd3416e 234 Hamap MF_01968 NAD-dependent protein deacetylase [cobB]. 6 234 56.617 T 28-03-2018 IPR028628 Sirtuin, class U GO:0034979|GO:0051287 ALX04_RS13505 70737d83daa7ce0938560d332fd3416e 234 SUPERFAMILY SSF52467 3 223 5.01E-63 T 28-03-2018 IPR029035 DHS-like NAD/FAD-binding domain ALX04_RS06250 057d05e4a1c177fa44391241ba547dad 154 Pfam PF07997 Protein of unknown function (DUF1694) 10 124 2.4E-38 T 28-03-2018 IPR012543 Protein of unknown function DUF1694 ALX04_RS06250 057d05e4a1c177fa44391241ba547dad 154 PIRSF PIRSF034303 3 154 3.7E-53 T 28-03-2018 IPR012543 Protein of unknown function DUF1694 ALX04_RS06250 057d05e4a1c177fa44391241ba547dad 154 Gene3D G3DSA:3.30.1330.30 7 128 2.6E-40 T 28-03-2018 IPR029064 50S ribosomal protein L30e-like ALX04_RS06250 057d05e4a1c177fa44391241ba547dad 154 SUPERFAMILY SSF160515 10 132 5.62E-39 T 28-03-2018 ALX04_RS15540 5735f4b2bde5f6a3d9b8916ea06e5a25 344 Gene3D G3DSA:1.10.10.60 12 56 1.5E-14 T 28-03-2018 ALX04_RS15540 5735f4b2bde5f6a3d9b8916ea06e5a25 344 SUPERFAMILY SSF53098 193 338 1.44E-14 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 ALX04_RS15540 5735f4b2bde5f6a3d9b8916ea06e5a25 344 Pfam PF13936 Helix-turn-helix domain 12 55 3.8E-15 T 28-03-2018 IPR025246 Transposase IS30-like HTH domain ALX04_RS15540 5735f4b2bde5f6a3d9b8916ea06e5a25 344 Gene3D G3DSA:3.30.420.10 185 343 2.6E-14 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 ALX04_RS12295 d5190139e1c5299208734c905302122f 235 Gene3D G3DSA:1.20.1080.10 1 235 1.8E-67 T 28-03-2018 IPR023271 Aquaporin-like Reactome: R-HSA-432047 ALX04_RS12295 d5190139e1c5299208734c905302122f 235 SUPERFAMILY SSF81338 2 230 4.32E-59 T 28-03-2018 IPR023271 Aquaporin-like Reactome: R-HSA-432047 ALX04_RS12295 d5190139e1c5299208734c905302122f 235 Pfam PF00230 Major intrinsic protein 4 228 4.7E-41 T 28-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 ALX04_RS12295 d5190139e1c5299208734c905302122f 235 ProSitePatterns PS00221 MIP family signature. 63 71 - T 28-03-2018 IPR022357 Major intrinsic protein, conserved site GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 ALX04_RS12295 d5190139e1c5299208734c905302122f 235 PRINTS PR00783 Major intrinsic protein family signature 82 101 7.9E-35 T 28-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 ALX04_RS12295 d5190139e1c5299208734c905302122f 235 PRINTS PR00783 Major intrinsic protein family signature 2 21 7.9E-35 T 28-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 ALX04_RS12295 d5190139e1c5299208734c905302122f 235 PRINTS PR00783 Major intrinsic protein family signature 45 69 7.9E-35 T 28-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 ALX04_RS12295 d5190139e1c5299208734c905302122f 235 PRINTS PR00783 Major intrinsic protein family signature 139 157 7.9E-35 T 28-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 ALX04_RS12295 d5190139e1c5299208734c905302122f 235 PRINTS PR00783 Major intrinsic protein family signature 167 189 7.9E-35 T 28-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 ALX04_RS12295 d5190139e1c5299208734c905302122f 235 PRINTS PR00783 Major intrinsic protein family signature 214 234 7.9E-35 T 28-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 ALX04_RS03775 18c979f4f384284a3da1d9920ec6c144 180 TIGRFAM TIGR03692 ATP_dep_HslV: ATP-dependent protease HslVU, peptidase subunit 8 180 3.9E-79 T 28-03-2018 IPR022281 ATP-dependent protease, HslV subunit GO:0004298|GO:0006508|GO:0009376 ALX04_RS03775 18c979f4f384284a3da1d9920ec6c144 180 Pfam PF00227 Proteasome subunit 7 176 6.4E-24 T 28-03-2018 IPR001353 Proteasome, subunit alpha/beta GO:0004298|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-446652|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8941858|Reactome: R-HSA-8951664|Reactome: R-HSA-983168 ALX04_RS03775 18c979f4f384284a3da1d9920ec6c144 180 Hamap MF_00248 ATP-dependent protease subunit HslV [hslV]. 7 180 39.371 T 28-03-2018 IPR022281 ATP-dependent protease, HslV subunit GO:0004298|GO:0006508|GO:0009376 ALX04_RS03775 18c979f4f384284a3da1d9920ec6c144 180 Gene3D G3DSA:3.60.20.10 8 180 9.0E-26 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal ALX04_RS03775 18c979f4f384284a3da1d9920ec6c144 180 SUPERFAMILY SSF56235 5 179 8.55E-54 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal ALX04_RS14175 bcddd1f6ade4bb424f015831a7e055a6 257 SUPERFAMILY SSF52096 4 248 1.15E-45 T 28-03-2018 IPR029045 ClpP/crotonase-like domain ALX04_RS14175 bcddd1f6ade4bb424f015831a7e055a6 257 Gene3D G3DSA:3.90.226.10 2 252 8.8E-32 T 28-03-2018 ALX04_RS14175 bcddd1f6ade4bb424f015831a7e055a6 257 Pfam PF03255 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit 8 92 1.6E-12 T 28-03-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 ALX04_RS14175 bcddd1f6ade4bb424f015831a7e055a6 257 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 98 111 4.4E-19 T 28-03-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 ALX04_RS14175 bcddd1f6ade4bb424f015831a7e055a6 257 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 32 43 4.4E-19 T 28-03-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 ALX04_RS14175 bcddd1f6ade4bb424f015831a7e055a6 257 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 79 95 4.4E-19 T 28-03-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 ALX04_RS14175 bcddd1f6ade4bb424f015831a7e055a6 257 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 142 151 4.4E-19 T 28-03-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 ALX04_RS14175 bcddd1f6ade4bb424f015831a7e055a6 257 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 58 76 4.4E-19 T 28-03-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 ALX04_RS14175 bcddd1f6ade4bb424f015831a7e055a6 257 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 114 127 4.4E-19 T 28-03-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 ALX04_RS15200 9dbf60260f5dc8d6dead3b97be15f8b4 293 Pfam PF01925 Sulfite exporter TauE/SafE 173 288 1.5E-9 T 28-03-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 ALX04_RS04625 f89544c0b55cb9f68bbdb0b35a532f11 261 ProSitePatterns PS01315 Phosphatidate cytidylyltransferase signature. 220 246 - T 28-03-2018 IPR000374 Phosphatidate cytidylyltransferase GO:0016020|GO:0016772 KEGG: 00564+2.7.7.41|KEGG: 04070+2.7.7.41|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7817 ALX04_RS04625 f89544c0b55cb9f68bbdb0b35a532f11 261 Pfam PF01148 Cytidylyltransferase family 3 258 1.6E-62 T 28-03-2018 ALX04_RS13590 7b7611d209c511fe01170e4e2d59535e 340 Gene3D G3DSA:3.40.50.620 155 298 1.3E-31 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold ALX04_RS13590 7b7611d209c511fe01170e4e2d59535e 340 Pfam PF02698 DUF218 domain 163 311 1.5E-30 T 28-03-2018 IPR003848 Domain of unknown function DUF218 ALX04_RS09750 4b46fca9115ea52dce85ee8bd79b1933 497 Gene3D G3DSA:3.40.1710.10 39 321 2.8E-21 T 28-03-2018 ALX04_RS09750 4b46fca9115ea52dce85ee8bd79b1933 497 TIGRFAM TIGR03061 pip_yhgE_Nterm: YhgE/Pip N-terminal domain 5 165 5.0E-52 T 28-03-2018 IPR017500 Phage infection protein, YhgE, N-terminal ALX04_RS09750 4b46fca9115ea52dce85ee8bd79b1933 497 Pfam PF12698 ABC-2 family transporter protein 20 476 4.5E-19 T 28-03-2018 ALX04_RS09750 4b46fca9115ea52dce85ee8bd79b1933 497 TIGRFAM TIGR03062 pip_yhgE_Cterm: YhgE/Pip C-terminal domain 286 478 4.5E-49 T 28-03-2018 IPR017501 Phage infection protein, YhgE, C-terminal ALX04_RS15050 e8b159692779c894083f9f632c1af746 660 Pfam PF01757 Acyltransferase family 30 361 2.8E-22 T 28-03-2018 IPR002656 Acyltransferase 3 GO:0016747 ALX04_RS15050 e8b159692779c894083f9f632c1af746 660 Gene3D G3DSA:3.40.50.1110 417 657 2.8E-18 T 28-03-2018 ALX04_RS15050 e8b159692779c894083f9f632c1af746 660 SUPERFAMILY SSF52266 499 655 3.21E-15 T 28-03-2018 IPR013830 SGNH hydrolase-type esterase domain ALX04_RS10115 c834767f24d5a8f46503619928f10eb4 75 Pfam PF13396 Phospholipase_D-nuclease N-terminal 33 73 3.0E-6 T 28-03-2018 IPR027379 Cardiolipin synthase N-terminal ALX04_RS06485 506e52a65aaeac7df3880a3fa30496b3 448 SUPERFAMILY SSF53623 225 297 1.72E-35 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 ALX04_RS06485 506e52a65aaeac7df3880a3fa30496b3 448 SUPERFAMILY SSF53623 40 191 1.72E-35 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 ALX04_RS06485 506e52a65aaeac7df3880a3fa30496b3 448 Gene3D G3DSA:3.40.1190.10 40 297 1.3E-38 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 ALX04_RS06485 506e52a65aaeac7df3880a3fa30496b3 448 Pfam PF08245 Mur ligase middle domain 54 188 5.5E-9 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 ALX04_RS06485 506e52a65aaeac7df3880a3fa30496b3 448 Pfam PF08353 Domain of unknown function (DUF1727) 320 430 6.9E-33 T 28-03-2018 IPR013564 Domain of unknown function DUF1727 ALX04_RS07565 301b49a7d7cd4646b3445eb2bfe90858 106 SUPERFAMILY SSF52833 6 102 9.74E-23 T 28-03-2018 IPR012336 Thioredoxin-like fold ALX04_RS07565 301b49a7d7cd4646b3445eb2bfe90858 106 Gene3D G3DSA:3.40.30.10 3 65 1.2E-14 T 28-03-2018 ALX04_RS07565 301b49a7d7cd4646b3445eb2bfe90858 106 Pfam PF00085 Thioredoxin 5 101 2.2E-14 T 28-03-2018 IPR013766 Thioredoxin domain GO:0045454 ALX04_RS07565 301b49a7d7cd4646b3445eb2bfe90858 106 Gene3D G3DSA:3.40.30.10 66 106 0.0089 T 28-03-2018 ALX04_RS09340 dc62c2de54534d72b0e59271799014fc 218 SUPERFAMILY SSF51735 1 192 3.1E-25 T 28-03-2018 IPR016040 NAD(P)-binding domain ALX04_RS09340 dc62c2de54534d72b0e59271799014fc 218 Pfam PF13460 NAD(P)H-binding 8 189 2.8E-38 T 28-03-2018 IPR016040 NAD(P)-binding domain ALX04_RS09340 dc62c2de54534d72b0e59271799014fc 218 Gene3D G3DSA:3.40.50.720 1 200 3.1E-18 T 28-03-2018 ALX04_RS09320 78d36ce07d01811c8d6a0e18d7fb4d23 164 TIGRFAM TIGR00481 TIGR00481: Raf kinase inhibitor-like protein, YbhB/YbcL family 21 161 4.4E-26 T 28-03-2018 IPR005247 YbhB/YbcL ALX04_RS09320 78d36ce07d01811c8d6a0e18d7fb4d23 164 SUPERFAMILY SSF49777 8 158 1.06E-30 T 28-03-2018 IPR008914 Phosphatidylethanolamine-binding protein ALX04_RS09320 78d36ce07d01811c8d6a0e18d7fb4d23 164 Gene3D G3DSA:3.90.280.10 2 161 3.9E-31 T 28-03-2018 IPR008914 Phosphatidylethanolamine-binding protein ALX04_RS09320 78d36ce07d01811c8d6a0e18d7fb4d23 164 Pfam PF01161 Phosphatidylethanolamine-binding protein 26 159 2.9E-25 T 28-03-2018 IPR008914 Phosphatidylethanolamine-binding protein ALX04_RS10240 5e1c615240107da27e7d9130c9f64ac3 680 Hamap MF_01522 Low affinity potassium transport system protein kup [kup]. 6 654 27.168 T 28-03-2018 IPR023051 Potassium uptake protein, low affinity, Kup ALX04_RS10240 5e1c615240107da27e7d9130c9f64ac3 680 Pfam PF02705 K+ potassium transporter 15 555 1.3E-164 T 28-03-2018 IPR003855 Potassium transporter GO:0015079|GO:0016020|GO:0071805 ALX04_RS10125 0a04bc460edad6d34636720c747cc5ad 183 SUPERFAMILY SSF55729 4 171 6.45E-35 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase ALX04_RS10125 0a04bc460edad6d34636720c747cc5ad 183 Pfam PF13302 Acetyltransferase (GNAT) domain 13 148 2.9E-17 T 28-03-2018 IPR000182 GNAT domain GO:0008080 ALX04_RS10125 0a04bc460edad6d34636720c747cc5ad 183 Gene3D G3DSA:3.40.630.30 2 180 6.6E-27 T 28-03-2018 ALX04_RS15640 71fe65c0dfa9f1db09beeae4eaa9357f 74 Gene3D G3DSA:1.10.10.10 1 73 4.7E-10 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS15640 71fe65c0dfa9f1db09beeae4eaa9357f 74 Pfam PF01051 Initiator Replication protein 2 68 5.3E-8 T 28-03-2018 IPR000525 Initiator Rep protein GO:0003887|GO:0005727|GO:0006270 ALX04_RS07480 708f6a2cea0427ad1c4b3b0f8411e131 184 SUPERFAMILY SSF52499 3 183 2.75E-55 T 28-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 ALX04_RS07480 708f6a2cea0427ad1c4b3b0f8411e131 184 Pfam PF00857 Isochorismatase family 6 181 4.4E-43 T 28-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 ALX04_RS07480 708f6a2cea0427ad1c4b3b0f8411e131 184 Gene3D G3DSA:3.40.50.850 1 184 1.3E-50 T 28-03-2018 ALX04_RS08885 f7ebb4ecd3c494238ffb074e270ccc4f 226 Gene3D G3DSA:3.20.20.450 2 224 9.9E-29 T 28-03-2018 IPR001633 EAL domain ALX04_RS08885 f7ebb4ecd3c494238ffb074e270ccc4f 226 SMART SM00052 2 217 3.5E-5 T 28-03-2018 IPR001633 EAL domain ALX04_RS08885 f7ebb4ecd3c494238ffb074e270ccc4f 226 SUPERFAMILY SSF141868 3 221 1.57E-32 T 28-03-2018 IPR001633 EAL domain ALX04_RS08885 f7ebb4ecd3c494238ffb074e270ccc4f 226 Pfam PF00563 EAL domain 4 212 8.5E-20 T 28-03-2018 IPR001633 EAL domain ALX04_RS07110 0e9d0dbb0204d2e7f7292a64a02cdd0b 312 SUPERFAMILY SSF103481 46 151 3.53E-11 T 28-03-2018 ALX04_RS07110 0e9d0dbb0204d2e7f7292a64a02cdd0b 312 SUPERFAMILY SSF103481 194 296 8.5E-10 T 28-03-2018 ALX04_RS07110 0e9d0dbb0204d2e7f7292a64a02cdd0b 312 Pfam PF00892 EamA-like transporter family 163 293 1.8E-17 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 ALX04_RS07110 0e9d0dbb0204d2e7f7292a64a02cdd0b 312 Pfam PF00892 EamA-like transporter family 8 148 3.8E-17 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 ALX04_RS08830 727ca7b620156d75c27bbf3beb0ddd86 303 SMART SM00530 7 61 5.0E-7 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 ALX04_RS08830 727ca7b620156d75c27bbf3beb0ddd86 303 SUPERFAMILY SSF47413 3 64 2.45E-12 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 ALX04_RS08830 727ca7b620156d75c27bbf3beb0ddd86 303 Gene3D G3DSA:1.10.3100.10 1 115 9.0E-11 T 28-03-2018 IPR027910 YdiL-like domain ALX04_RS08830 727ca7b620156d75c27bbf3beb0ddd86 303 Pfam PF01381 Helix-turn-helix 8 61 1.2E-5 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 ALX04_RS03950 72668d5073043339e958d1011953ca75 204 PIRSF PIRSF037778 2 189 2.0E-37 T 28-03-2018 IPR025720 ECF transporter, Riboflavin transporter RibU GO:0005886|GO:0032217|GO:0032218 ALX04_RS03950 72668d5073043339e958d1011953ca75 204 Pfam PF12822 ECF transporter, substrate-specific component 8 177 1.7E-17 T 28-03-2018 IPR024529 ECF transporter, substrate-specific component GO:0005215 ALX04_RS14365 b8e579fb9b6a59863d2f3930f694fe71 565 Pfam PF12169 DNA polymerase III subunits gamma and tau domain III 232 359 1.8E-10 T 28-03-2018 IPR022754 DNA polymerase III, gamma subunit, domain III GO:0003887 ALX04_RS14365 b8e579fb9b6a59863d2f3930f694fe71 565 Gene3D G3DSA:1.10.8.60 166 241 4.1E-19 T 28-03-2018 ALX04_RS14365 b8e579fb9b6a59863d2f3930f694fe71 565 Pfam PF13177 DNA polymerase III, delta subunit 19 177 2.8E-44 T 28-03-2018 ALX04_RS14365 b8e579fb9b6a59863d2f3930f694fe71 565 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 40 58 1.4E-5 T 28-03-2018 IPR001270 ClpA/B family GO:0005524 ALX04_RS14365 b8e579fb9b6a59863d2f3930f694fe71 565 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 123 141 1.4E-5 T 28-03-2018 IPR001270 ClpA/B family GO:0005524 ALX04_RS14365 b8e579fb9b6a59863d2f3930f694fe71 565 Gene3D G3DSA:1.20.272.10 242 363 1.0E-16 T 28-03-2018 ALX04_RS14365 b8e579fb9b6a59863d2f3930f694fe71 565 SUPERFAMILY SSF48019 243 359 6.21E-21 T 28-03-2018 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 ALX04_RS14365 b8e579fb9b6a59863d2f3930f694fe71 565 SMART SM00382 36 178 2.2E-13 T 28-03-2018 IPR003593 AAA+ ATPase domain ALX04_RS14365 b8e579fb9b6a59863d2f3930f694fe71 565 SUPERFAMILY SSF52540 32 220 3.1E-57 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase ALX04_RS14365 b8e579fb9b6a59863d2f3930f694fe71 565 TIGRFAM TIGR02397 dnaX_nterm: DNA polymerase III, subunit gamma and tau 2 356 7.0E-140 T 28-03-2018 IPR012763 DNA polymerase III, subunit gamma/ tau GO:0003887|GO:0005524|GO:0006260|GO:0009360 ALX04_RS14365 b8e579fb9b6a59863d2f3930f694fe71 565 Gene3D G3DSA:3.40.50.300 14 165 3.4E-40 T 28-03-2018 ALX04_RS02510 ec1c133ec125b53f1cfe8cb4ee38bfce 169 Gene3D G3DSA:1.10.3210.10 16 166 1.3E-15 T 28-03-2018 ALX04_RS02510 ec1c133ec125b53f1cfe8cb4ee38bfce 169 SUPERFAMILY SSF109604 17 144 1.04E-17 T 28-03-2018 ALX04_RS15295 5c659b46acb770aa4a72350a1610dca0 122 SMART SM00530 12 68 1.2E-11 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 ALX04_RS15295 5c659b46acb770aa4a72350a1610dca0 122 Pfam PF01381 Helix-turn-helix 15 68 1.6E-11 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 ALX04_RS15295 5c659b46acb770aa4a72350a1610dca0 122 Gene3D G3DSA:1.10.260.40 2 122 6.6E-18 T 28-03-2018 ALX04_RS15295 5c659b46acb770aa4a72350a1610dca0 122 SUPERFAMILY SSF47413 6 73 9.38E-13 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 ALX04_RS02235 a295c2025b65222ce6175ff80e3867a4 213 Pfam PF01588 Putative tRNA binding domain 97 196 2.2E-16 T 28-03-2018 IPR002547 tRNA-binding domain GO:0000049 Reactome: R-HSA-379716 ALX04_RS02235 a295c2025b65222ce6175ff80e3867a4 213 Gene3D G3DSA:3.30.1940.10 23 91 9.2E-25 T 28-03-2018 IPR027855 Domain of unknown function DUF4479 ALX04_RS02235 a295c2025b65222ce6175ff80e3867a4 213 SUPERFAMILY SSF50249 94 203 7.59E-27 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold ALX04_RS02235 a295c2025b65222ce6175ff80e3867a4 213 Pfam PF14794 Domain of unknown function (DUF4479) 21 92 1.0E-25 T 28-03-2018 IPR027855 Domain of unknown function DUF4479 ALX04_RS02235 a295c2025b65222ce6175ff80e3867a4 213 Gene3D G3DSA:2.40.50.140 92 205 4.5E-29 T 28-03-2018 ALX04_RS00175 5ee1fe020609788529b95d2b284cca9b 72 Pfam PF13411 MerR HTH family regulatory protein 1 63 8.8E-8 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 ALX04_RS00175 5ee1fe020609788529b95d2b284cca9b 72 SUPERFAMILY SSF46955 1 66 4.03E-7 T 28-03-2018 IPR009061 Putative DNA-binding domain ALX04_RS00175 5ee1fe020609788529b95d2b284cca9b 72 Gene3D G3DSA:1.10.1660.10 1 68 1.7E-4 T 28-03-2018 ALX04_RS13310 7174be2f23e7b8407da00e1dc8857d1e 384 Gene3D G3DSA:1.20.1250.20 199 380 1.7E-7 T 28-03-2018 ALX04_RS13310 7174be2f23e7b8407da00e1dc8857d1e 384 Pfam PF07690 Major Facilitator Superfamily 20 308 6.0E-25 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 ALX04_RS13310 7174be2f23e7b8407da00e1dc8857d1e 384 Gene3D G3DSA:1.20.1250.20 4 197 2.1E-24 T 28-03-2018 ALX04_RS13310 7174be2f23e7b8407da00e1dc8857d1e 384 SUPERFAMILY SSF103473 5 375 5.62E-41 T 28-03-2018 IPR020846 Major facilitator superfamily domain ALX04_RS13015 0654106c248f866544b2baa58f0a18cf 455 SUPERFAMILY SSF53720 13 454 1.7E-75 T 28-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 ALX04_RS13015 0654106c248f866544b2baa58f0a18cf 455 Gene3D G3DSA:3.40.309.10 235 412 1.4E-24 T 28-03-2018 ALX04_RS13015 0654106c248f866544b2baa58f0a18cf 455 Pfam PF00171 Aldehyde dehydrogenase family 12 271 2.5E-21 T 28-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 ALX04_RS13015 0654106c248f866544b2baa58f0a18cf 455 Gene3D G3DSA:3.40.605.10 3 234 1.5E-28 T 28-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 ALX04_RS08910 67155de5078284956859f259585f99a7 333 Pfam PF02424 ApbE family 28 298 1.8E-64 T 28-03-2018 IPR024932 Flavin transferase ApbE GO:0017013 ALX04_RS08910 67155de5078284956859f259585f99a7 333 PIRSF PIRSF006268 1 328 8.6E-78 T 28-03-2018 IPR024932 Flavin transferase ApbE GO:0017013 ALX04_RS08910 67155de5078284956859f259585f99a7 333 SUPERFAMILY SSF143631 21 311 1.91E-77 T 28-03-2018 IPR003374 ApbE-like domain ALX04_RS08910 67155de5078284956859f259585f99a7 333 Gene3D G3DSA:3.10.520.10 9 320 3.1E-41 T 28-03-2018 ALX04_RS08220 a19f59a0f05100326f87dfea4190ef89 148 Pfam PF00258 Flavodoxin 6 119 7.0E-17 T 28-03-2018 IPR008254 Flavodoxin/nitric oxide synthase GO:0010181 ALX04_RS08220 a19f59a0f05100326f87dfea4190ef89 148 Gene3D G3DSA:3.40.50.360 5 146 1.1E-25 T 28-03-2018 IPR029039 Flavoprotein-like domain ALX04_RS08220 a19f59a0f05100326f87dfea4190ef89 148 SUPERFAMILY SSF52218 1 146 2.93E-32 T 28-03-2018 IPR029039 Flavoprotein-like domain ALX04_RS05870 c3d98afab57259ef2ef6c2b22bee3ed9 194 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 37 57 - T 28-03-2018 IPR012902 Prokaryotic N-terminal methylation site ALX04_RS05870 c3d98afab57259ef2ef6c2b22bee3ed9 194 Pfam PF07963 Prokaryotic N-terminal methylation motif 33 58 2.7E-7 T 28-03-2018 IPR012902 Prokaryotic N-terminal methylation site ALX04_RS05870 c3d98afab57259ef2ef6c2b22bee3ed9 194 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 36 56 2.8E-5 T 28-03-2018 IPR012902 Prokaryotic N-terminal methylation site ALX04_RS10715 c290c7196a8ca019929300e58a456176 1136 Gene3D G3DSA:2.60.40.10 715 805 0.45 T 28-03-2018 IPR013783 Immunoglobulin-like fold ALX04_RS10715 c290c7196a8ca019929300e58a456176 1136 Pfam PF13731 WxL domain surface cell wall-binding 924 1134 2.1E-31 T 28-03-2018 IPR027994 WxL domain ALX04_RS10715 c290c7196a8ca019929300e58a456176 1136 Gene3D G3DSA:2.60.40.1310 806 916 1.1E-8 T 28-03-2018 ALX04_RS11895 340540524440d1962623cedf06a883ff 294 SUPERFAMILY SSF103481 186 286 1.7E-9 T 28-03-2018 ALX04_RS11895 340540524440d1962623cedf06a883ff 294 SUPERFAMILY SSF103481 44 139 4.97E-11 T 28-03-2018 ALX04_RS11895 340540524440d1962623cedf06a883ff 294 Pfam PF00892 EamA-like transporter family 7 139 9.0E-11 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 ALX04_RS11895 340540524440d1962623cedf06a883ff 294 Pfam PF00892 EamA-like transporter family 152 283 7.3E-10 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 ALX04_RS03330 4b917cdd7798ae2e570a56c97c0b844e 166 SUPERFAMILY SSF54403 39 103 1.22E-13 T 28-03-2018 ALX04_RS03330 4b917cdd7798ae2e570a56c97c0b844e 166 Gene3D G3DSA:3.10.450.40 34 98 6.0E-17 T 28-03-2018 ALX04_RS03330 4b917cdd7798ae2e570a56c97c0b844e 166 Gene3D G3DSA:3.10.450.40 103 165 4.3E-11 T 28-03-2018 ALX04_RS03330 4b917cdd7798ae2e570a56c97c0b844e 166 SUPERFAMILY SSF54403 103 163 5.27E-16 T 28-03-2018 ALX04_RS13335 b6a2bc75e3dd0d1af75fe05765aff025 394 Pfam PF00999 Sodium/hydrogen exchanger family 8 374 6.4E-75 T 28-03-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 ALX04_RS13335 b6a2bc75e3dd0d1af75fe05765aff025 394 Gene3D G3DSA:1.20.91.10 229 308 4.7E-13 T 28-03-2018 ALX04_RS10095 e44d552d31c2ebf599ae2d6c4e45c8a4 424 SUPERFAMILY SSF52777 14 141 2.22E-5 T 28-03-2018 ALX04_RS10095 e44d552d31c2ebf599ae2d6c4e45c8a4 424 SUPERFAMILY SSF52777 185 347 1.22E-11 T 28-03-2018 ALX04_RS08090 7a49b89dd19a0718f4e49d88153bbb83 122 PRINTS PR00332 Histidine triad family signature 86 96 2.0E-7 T 28-03-2018 IPR001310 Histidine triad (HIT) protein ALX04_RS08090 7a49b89dd19a0718f4e49d88153bbb83 122 PRINTS PR00332 Histidine triad family signature 19 37 2.0E-7 T 28-03-2018 IPR001310 Histidine triad (HIT) protein ALX04_RS08090 7a49b89dd19a0718f4e49d88153bbb83 122 Pfam PF01230 HIT domain 11 100 6.4E-22 T 28-03-2018 IPR001310 Histidine triad (HIT) protein ALX04_RS08090 7a49b89dd19a0718f4e49d88153bbb83 122 Gene3D G3DSA:3.30.428.10 1 116 1.5E-30 T 28-03-2018 IPR011146 HIT-like domain GO:0003824 ALX04_RS08090 7a49b89dd19a0718f4e49d88153bbb83 122 SUPERFAMILY SSF54197 1 114 9.43E-36 T 28-03-2018 IPR011146 HIT-like domain GO:0003824 ALX04_RS02285 afa64b4b43eb99837e874523bf7772f8 468 SUPERFAMILY SSF101960 36 465 1.2E-136 T 28-03-2018 ALX04_RS02285 afa64b4b43eb99837e874523bf7772f8 468 TIGRFAM TIGR01980 sufB: FeS assembly protein SufB 13 459 1.0E-210 T 28-03-2018 IPR010231 SUF system FeS cluster assembly, SufB GO:0016226 ALX04_RS02285 afa64b4b43eb99837e874523bf7772f8 468 Pfam PF01458 Uncharacterized protein family (UPF0051) 214 439 3.1E-72 T 28-03-2018 IPR000825 SUF system FeS cluster assembly, SufBD GO:0016226 ALX04_RS06175 bfb4064de14eeef507b333b5ed982cda 172 TIGRFAM TIGR03426 shape_MreD: rod shape-determining protein MreD 11 165 8.3E-25 T 28-03-2018 IPR007227 Cell shape-determining protein MreD GO:0008360|GO:0016021 ALX04_RS06175 bfb4064de14eeef507b333b5ed982cda 172 Pfam PF04093 rod shape-determining protein MreD 9 168 3.3E-15 T 28-03-2018 IPR007227 Cell shape-determining protein MreD GO:0008360|GO:0016021 ALX04_RS00955 c946d22924d721d2928e0a584da456df 146 SUPERFAMILY SSF52402 5 146 8.37E-30 T 28-03-2018 ALX04_RS00955 c946d22924d721d2928e0a584da456df 146 PRINTS PR01438 Universal stress protein signature 124 146 9.4E-15 T 28-03-2018 IPR006015 Universal stress protein A ALX04_RS00955 c946d22924d721d2928e0a584da456df 146 PRINTS PR01438 Universal stress protein signature 5 23 9.4E-15 T 28-03-2018 IPR006015 Universal stress protein A ALX04_RS00955 c946d22924d721d2928e0a584da456df 146 PRINTS PR01438 Universal stress protein signature 106 118 9.4E-15 T 28-03-2018 IPR006015 Universal stress protein A ALX04_RS00955 c946d22924d721d2928e0a584da456df 146 Gene3D G3DSA:3.40.50.620 1 146 1.4E-33 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold ALX04_RS00955 c946d22924d721d2928e0a584da456df 146 Pfam PF00582 Universal stress protein family 5 146 1.7E-29 T 28-03-2018 IPR006016 UspA GO:0006950 ALX04_RS00955 c946d22924d721d2928e0a584da456df 146 PIRSF PIRSF006276 1 146 3.5E-17 T 28-03-2018 IPR006015 Universal stress protein A ALX04_RS07145 e48a62561d00504cc4cc773990b973b8 287 Gene3D G3DSA:3.40.50.1820 43 287 6.1E-21 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold ALX04_RS07145 e48a62561d00504cc4cc773990b973b8 287 SUPERFAMILY SSF53474 45 224 3.21E-11 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold ALX04_RS07145 e48a62561d00504cc4cc773990b973b8 287 Pfam PF06028 Alpha/beta hydrolase of unknown function (DUF915) 38 286 4.8E-67 T 28-03-2018 IPR010315 Protein of unknown function DUF915, hydrolase-like ALX04_RS09155 48517fc21007f91e532078ce925c25a2 226 Pfam PF09335 SNARE associated Golgi protein 75 187 7.5E-12 T 28-03-2018 IPR032816 SNARE associated Golgi protein ALX04_RS11500 5e5ed754d3c878180f4399222ae611b3 288 SUPERFAMILY SSF82549 1 284 3.92E-85 T 28-03-2018 ALX04_RS11500 5e5ed754d3c878180f4399222ae611b3 288 Pfam PF02645 Uncharacterised protein, DegV family COG1307 2 280 5.5E-77 T 28-03-2018 IPR003797 DegV ALX04_RS11500 5e5ed754d3c878180f4399222ae611b3 288 TIGRFAM TIGR00762 DegV: EDD domain protein, DegV family 3 279 3.3E-90 T 28-03-2018 IPR003797 DegV ALX04_RS11500 5e5ed754d3c878180f4399222ae611b3 288 Gene3D G3DSA:3.30.1180.10 154 287 1.7E-32 T 28-03-2018 ALX04_RS11500 5e5ed754d3c878180f4399222ae611b3 288 Gene3D G3DSA:3.40.50.10170 1 153 7.8E-44 T 28-03-2018 ALX04_RS03825 5125e2d821fec9bc9a5d4e728f434cff 232 Gene3D G3DSA:3.40.50.720 5 223 3.4E-18 T 28-03-2018 ALX04_RS03825 5125e2d821fec9bc9a5d4e728f434cff 232 Pfam PF03807 NADP oxidoreductase coenzyme F420-dependent 6 94 1.9E-13 T 28-03-2018 IPR028939 Pyrroline-5-carboxylate reductase, catalytic, N-terminal ALX04_RS03825 5125e2d821fec9bc9a5d4e728f434cff 232 SUPERFAMILY SSF51735 6 196 3.29E-26 T 28-03-2018 IPR016040 NAD(P)-binding domain ALX04_RS01815 33b53a12f0d7de98359d67ab7eaef182 95 SUPERFAMILY SSF117782 1 92 1.44E-6 T 28-03-2018 IPR002765 Uncharacterised protein family UPF0145 ALX04_RS01815 33b53a12f0d7de98359d67ab7eaef182 95 Gene3D G3DSA:3.30.110.70 25 90 0.0018 T 28-03-2018 IPR035439 Uncharacterised protein family UPF0145/C2CD5 Reactome: R-HSA-1445148 ALX04_RS02570 c85cba3af63810bd2e77c6b55da029f5 881 Pfam PF09586 Bacterial membrane protein YfhO 17 861 2.7E-261 T 28-03-2018 IPR018580 Uncharacterised protein family YfhO ALX04_RS08305 3ffcc4eda40c30b414fecca09fc0f8cb 432 SUPERFAMILY SSF51445 28 222 2.0E-34 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily ALX04_RS08305 3ffcc4eda40c30b414fecca09fc0f8cb 432 Pfam PF01183 Glycosyl hydrolases family 25 32 200 5.4E-19 T 28-03-2018 IPR002053 Glycoside hydrolase, family 25 GO:0003796|GO:0009253|GO:0016998 ALX04_RS08305 3ffcc4eda40c30b414fecca09fc0f8cb 432 Gene3D G3DSA:3.20.20.80 14 214 1.2E-26 T 28-03-2018 ALX04_RS16020 0752f283a1885a08a7498d8fdca4f52a 678 Pfam PF02705 K+ potassium transporter 14 555 8.2E-168 T 28-03-2018 IPR003855 Potassium transporter GO:0015079|GO:0016020|GO:0071805 ALX04_RS16020 0752f283a1885a08a7498d8fdca4f52a 678 Hamap MF_01522 Low affinity potassium transport system protein kup [kup]. 5 654 27.157 T 28-03-2018 IPR023051 Potassium uptake protein, low affinity, Kup ALX04_RS06205 fcb026fb51f731b06143fe41b724a93b 164 Gene3D G3DSA:3.40.30.10 3 164 2.7E-25 T 28-03-2018 ALX04_RS06205 fcb026fb51f731b06143fe41b724a93b 164 SUPERFAMILY SSF52833 2 158 1.18E-33 T 28-03-2018 IPR012336 Thioredoxin-like fold ALX04_RS06205 fcb026fb51f731b06143fe41b724a93b 164 Pfam PF00578 AhpC/TSA family 20 140 9.8E-16 T 28-03-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 ALX04_RS08005 525af37884d7d3811960c63b37e2522f 156 Pfam PF00582 Universal stress protein family 5 146 3.0E-26 T 28-03-2018 IPR006016 UspA GO:0006950 ALX04_RS08005 525af37884d7d3811960c63b37e2522f 156 PRINTS PR01438 Universal stress protein signature 5 23 5.3E-14 T 28-03-2018 IPR006015 Universal stress protein A ALX04_RS08005 525af37884d7d3811960c63b37e2522f 156 PRINTS PR01438 Universal stress protein signature 106 118 5.3E-14 T 28-03-2018 IPR006015 Universal stress protein A ALX04_RS08005 525af37884d7d3811960c63b37e2522f 156 PRINTS PR01438 Universal stress protein signature 124 146 5.3E-14 T 28-03-2018 IPR006015 Universal stress protein A ALX04_RS08005 525af37884d7d3811960c63b37e2522f 156 Gene3D G3DSA:3.40.50.620 2 152 4.8E-28 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold ALX04_RS08005 525af37884d7d3811960c63b37e2522f 156 SUPERFAMILY SSF52402 5 150 6.03E-29 T 28-03-2018 ALX04_RS07490 f05fb31dc2bfbc1979c98365d61a132c 236 Pfam PF00005 ABC transporter 19 153 6.4E-20 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 ALX04_RS07490 f05fb31dc2bfbc1979c98365d61a132c 236 SUPERFAMILY SSF52540 3 218 2.71E-39 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase ALX04_RS07490 f05fb31dc2bfbc1979c98365d61a132c 236 SMART SM00382 28 202 2.4E-9 T 28-03-2018 IPR003593 AAA+ ATPase domain ALX04_RS07490 f05fb31dc2bfbc1979c98365d61a132c 236 Gene3D G3DSA:3.40.50.300 1 229 1.5E-38 T 28-03-2018 ALX04_RS02070 f17fea795a86b39ed8626f5f10f9e15d 146 Gene3D G3DSA:3.40.50.450 1 146 8.1E-31 T 28-03-2018 ALX04_RS02070 f17fea795a86b39ed8626f5f10f9e15d 146 Pfam PF05014 Nucleoside 2-deoxyribosyltransferase 4 110 1.0E-18 T 28-03-2018 IPR007710 Nucleoside 2-deoxyribosyltransferase GO:0009159|GO:0050144|GO:0070694 Reactome: R-HSA-74259 ALX04_RS02070 f17fea795a86b39ed8626f5f10f9e15d 146 SUPERFAMILY SSF52309 1 144 1.19E-41 T 28-03-2018 ALX04_RS01975 236686225f1b1f5ead1c06839e971d44 394 Gene3D G3DSA:1.20.1250.20 199 394 9.2E-8 T 28-03-2018 ALX04_RS01975 236686225f1b1f5ead1c06839e971d44 394 Gene3D G3DSA:1.20.1250.20 1 197 1.5E-10 T 28-03-2018 ALX04_RS01975 236686225f1b1f5ead1c06839e971d44 394 SUPERFAMILY SSF103473 8 383 1.57E-20 T 28-03-2018 IPR020846 Major facilitator superfamily domain ALX04_RS01950 e50f760e4fbd176efda16fcc5c654e49 156 Pfam PF11687 Domain of unknown function (DUF3284) 8 118 1.2E-25 T 28-03-2018 IPR021701 Protein of unknown function DUF3284 ALX04_RS03095 9862bec84001e25c80790ebe23ccad2d 166 SUPERFAMILY SSF54637 1 147 2.49E-26 T 28-03-2018 IPR029069 HotDog domain ALX04_RS03095 9862bec84001e25c80790ebe23ccad2d 166 Pfam PF03061 Thioesterase superfamily 26 93 9.2E-8 T 28-03-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 ALX04_RS03095 9862bec84001e25c80790ebe23ccad2d 166 Gene3D G3DSA:3.10.129.10 1 157 1.2E-25 T 28-03-2018 ALX04_RS10425 32d562579df6024b6c25d71e38904ee6 213 SUPERFAMILY SSF52266 10 212 5.8E-43 T 28-03-2018 IPR013830 SGNH hydrolase-type esterase domain ALX04_RS10425 32d562579df6024b6c25d71e38904ee6 213 Gene3D G3DSA:3.40.50.1110 7 213 4.0E-27 T 28-03-2018 ALX04_RS10425 32d562579df6024b6c25d71e38904ee6 213 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 16 200 4.3E-17 T 28-03-2018 IPR013830 SGNH hydrolase-type esterase domain ALX04_RS08165 107c8beead417b74d06f37ee5b8c00a7 105 Pfam PF02302 PTS system, Lactose/Cellobiose specific IIB subunit 6 96 1.9E-25 T 28-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 ALX04_RS08165 107c8beead417b74d06f37ee5b8c00a7 105 SUPERFAMILY SSF52794 4 102 1.96E-34 T 28-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 ALX04_RS08165 107c8beead417b74d06f37ee5b8c00a7 105 Gene3D G3DSA:3.40.50.2300 5 105 2.1E-36 T 28-03-2018 ALX04_RS02495 e7bfda5dd7da999849adc99c2f4c6f4c 307 TIGRFAM TIGR03592 yidC_oxa1_cterm: membrane protein insertase, YidC/Oxa1 family 58 247 5.9E-47 T 28-03-2018 IPR028055 Membrane insertase YidC/Oxa1, C-terminal ALX04_RS02495 e7bfda5dd7da999849adc99c2f4c6f4c 307 Gene3D G3DSA:1.20.1250.20 2 266 4.4E-5 T 28-03-2018 ALX04_RS02495 e7bfda5dd7da999849adc99c2f4c6f4c 307 Pfam PF02096 60Kd inner membrane protein 59 247 1.2E-42 T 28-03-2018 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 ALX04_RS02495 e7bfda5dd7da999849adc99c2f4c6f4c 307 Hamap MF_01811 Membrane protein insertase YidC [yidC]. 4 250 28.161 T 28-03-2018 IPR023060 Membrane insertase YidC/YidC1/YidC2, Firmicutes ALX04_RS02495 e7bfda5dd7da999849adc99c2f4c6f4c 307 PRINTS PR00701 60kDa inner membrane protein signature 131 154 8.6E-8 T 28-03-2018 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 ALX04_RS02495 e7bfda5dd7da999849adc99c2f4c6f4c 307 PRINTS PR00701 60kDa inner membrane protein signature 214 237 8.6E-8 T 28-03-2018 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 ALX04_RS08625 1ec1974ddaeb5e8a1690eb5ead505527 212 SUPERFAMILY SSF51735 1 196 3.41E-23 T 28-03-2018 IPR016040 NAD(P)-binding domain ALX04_RS08625 1ec1974ddaeb5e8a1690eb5ead505527 212 Pfam PF13460 NAD(P)H-binding 7 187 2.8E-37 T 28-03-2018 IPR016040 NAD(P)-binding domain ALX04_RS08625 1ec1974ddaeb5e8a1690eb5ead505527 212 Gene3D G3DSA:3.40.50.720 1 134 1.5E-15 T 28-03-2018 ALX04_RS05410 723863ae7c45c8197b981d056d1e9e6d 344 Gene3D G3DSA:2.60.40.1710 47 171 8.8E-8 T 28-03-2018 ALX04_RS05410 723863ae7c45c8197b981d056d1e9e6d 344 Pfam PF06030 Bacterial protein of unknown function (DUF916) 38 155 2.5E-29 T 28-03-2018 IPR010317 Protein of unknown function DUF916, cell surface putative ALX04_RS05410 723863ae7c45c8197b981d056d1e9e6d 344 Pfam PF11797 Protein of unknown function C-terminal (DUF3324) 168 305 5.2E-38 T 28-03-2018 IPR021759 Domain of unknown function DUF3324, C-terminal ALX04_RS08675 f9e1767240d9b3e6c83788ef0f17ea87 212 SUPERFAMILY SSF51735 1 193 7.31E-23 T 28-03-2018 IPR016040 NAD(P)-binding domain ALX04_RS08675 f9e1767240d9b3e6c83788ef0f17ea87 212 Pfam PF13460 NAD(P)H-binding 7 187 2.0E-37 T 28-03-2018 IPR016040 NAD(P)-binding domain ALX04_RS08675 f9e1767240d9b3e6c83788ef0f17ea87 212 Gene3D G3DSA:3.40.50.720 1 134 1.2E-16 T 28-03-2018 ALX04_RS06690 35019dd5fa03af732c626e2040dd7d6c 172 Pfam PF03592 Terminase small subunit 5 135 3.3E-30 T 28-03-2018 IPR005335 Terminase small subunit GO:0006323 ALX04_RS14030 dfe1b47028b092c3e96d027854853844 111 Gene3D G3DSA:2.60.120.10 1 111 2.3E-20 T 28-03-2018 IPR014710 RmlC-like jelly roll fold ALX04_RS14030 dfe1b47028b092c3e96d027854853844 111 Pfam PF07883 Cupin domain 43 107 6.0E-8 T 28-03-2018 IPR013096 Cupin 2, conserved barrel ALX04_RS14030 dfe1b47028b092c3e96d027854853844 111 SUPERFAMILY SSF51182 3 109 5.35E-23 T 28-03-2018 IPR011051 RmlC-like cupin domain ALX04_RS01220 81f7b3c2b7f20aef2b670661fb851146 127 Pfam PF02397 Bacterial sugar transferase 6 121 9.7E-44 T 28-03-2018 IPR003362 Bacterial sugar transferase ALX04_RS11085 a8531a2f8e935a641889844356ccf6c0 413 SUPERFAMILY SSF103473 13 398 8.11E-36 T 28-03-2018 IPR020846 Major facilitator superfamily domain ALX04_RS11085 a8531a2f8e935a641889844356ccf6c0 413 Gene3D G3DSA:1.20.1250.20 217 399 2.4E-8 T 28-03-2018 ALX04_RS11085 a8531a2f8e935a641889844356ccf6c0 413 Pfam PF07690 Major Facilitator Superfamily 15 249 4.8E-18 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 ALX04_RS11085 a8531a2f8e935a641889844356ccf6c0 413 Gene3D G3DSA:1.20.1250.20 2 216 6.7E-27 T 28-03-2018 ALX04_RS11085 a8531a2f8e935a641889844356ccf6c0 413 ProSitePatterns PS00216 Sugar transport proteins signature 1. 76 92 - T 28-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 ALX04_RS08775 dccfef50a71fdc90532e65b65dd31e36 567 Gene3D G3DSA:3.90.350.10 230 491 4.3E-8 T 28-03-2018 IPR014736 Transposase, Tn5-like, core ALX04_RS08775 dccfef50a71fdc90532e65b65dd31e36 567 Pfam PF01609 Transposase DDE domain 257 508 9.4E-33 T 28-03-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 ALX04_RS08775 dccfef50a71fdc90532e65b65dd31e36 567 Pfam PF05598 Transposase domain (DUF772) 45 101 1.7E-11 T 28-03-2018 IPR008490 Transposase InsH, N-terminal ALX04_RS04375 cb610bc53ed1d819cd62376f4982f6d7 147 SUPERFAMILY SSF89095 1 147 7.85E-46 T 28-03-2018 IPR003789 Aspartyl/glutamyl-tRNA amidotransferase subunit B-related GO:0016884 ALX04_RS04375 cb610bc53ed1d819cd62376f4982f6d7 147 Gene3D G3DSA:1.10.1510.10 1 90 2.7E-29 T 28-03-2018 ALX04_RS04375 cb610bc53ed1d819cd62376f4982f6d7 147 Pfam PF09424 Yqey-like protein 5 146 1.4E-54 T 28-03-2018 IPR019004 Uncharacterised domain YOR215C, mitochondrial ALX04_RS04375 cb610bc53ed1d819cd62376f4982f6d7 147 Gene3D G3DSA:1.10.10.410 91 147 1.8E-21 T 28-03-2018 IPR023168 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, C-terminal ALX04_RS13005 df39557242a98673d0ae22604ac55601 297 SMART SM00382 27 205 3.2E-9 T 28-03-2018 IPR003593 AAA+ ATPase domain ALX04_RS13005 df39557242a98673d0ae22604ac55601 297 Pfam PF00005 ABC transporter 18 155 3.2E-18 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 ALX04_RS13005 df39557242a98673d0ae22604ac55601 297 Gene3D G3DSA:3.40.50.300 1 237 1.0E-39 T 28-03-2018 ALX04_RS13005 df39557242a98673d0ae22604ac55601 297 SUPERFAMILY SSF52540 3 221 2.76E-41 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase ALX04_RS12095 bc94e6ee0ad1cf42d8093e8c55163ee9 101 SUPERFAMILY SSF143430 1 83 8.37E-14 T 28-03-2018 ALX04_RS12095 bc94e6ee0ad1cf42d8093e8c55163ee9 101 TIGRFAM TIGR01573 cas2: CRISPR-associated endonuclease Cas2 1 91 5.8E-21 T 28-03-2018 IPR021127 CRISPR-associated endonuclease Cas2 GO:0004521|GO:0043571 ALX04_RS12095 bc94e6ee0ad1cf42d8093e8c55163ee9 101 Hamap MF_01471 CRISPR-associated endoribonuclease Cas2 [cas2]. 1 92 12.9 T 28-03-2018 IPR021127 CRISPR-associated endonuclease Cas2 GO:0004521|GO:0043571 ALX04_RS12095 bc94e6ee0ad1cf42d8093e8c55163ee9 101 Pfam PF09827 CRISPR associated protein Cas2 1 79 7.5E-17 T 28-03-2018 IPR019199 Virulence-associated protein D / CRISPR associated protein Cas2 ALX04_RS12095 bc94e6ee0ad1cf42d8093e8c55163ee9 101 Gene3D G3DSA:3.30.70.240 1 100 3.4E-15 T 28-03-2018 ALX04_RS14350 5f1de3645baad14e8791a663048cc42e 202 Pfam PF05175 Methyltransferase small domain 28 197 8.7E-47 T 28-03-2018 IPR007848 Methyltransferase small domain GO:0008168 ALX04_RS14350 5f1de3645baad14e8791a663048cc42e 202 Gene3D G3DSA:3.40.50.150 19 202 4.5E-25 T 28-03-2018 ALX04_RS14350 5f1de3645baad14e8791a663048cc42e 202 SUPERFAMILY SSF53335 8 200 3.47E-32 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase ALX04_RS15100 75f1278b11d1645344887efa688123d8 147 Pfam PF01475 Ferric uptake regulator family 15 133 4.7E-22 T 28-03-2018 IPR002481 Ferric-uptake regulator GO:0003700|GO:0006355 ALX04_RS15100 75f1278b11d1645344887efa688123d8 147 SUPERFAMILY SSF46785 6 137 6.89E-30 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS15100 75f1278b11d1645344887efa688123d8 147 Gene3D G3DSA:1.10.10.10 8 96 8.5E-13 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS06190 48541751c7ee27487bf91fdc79a7b693 211 SUPERFAMILY SSF102712 119 182 7.98E-6 T 28-03-2018 ALX04_RS06190 48541751c7ee27487bf91fdc79a7b693 211 Gene3D G3DSA:3.40.140.10 82 205 2.4E-40 T 28-03-2018 ALX04_RS06190 48541751c7ee27487bf91fdc79a7b693 211 Pfam PF04002 RadC-like JAB domain 87 203 3.8E-39 T 28-03-2018 IPR025657 RadC-like JAB domain ALX04_RS06190 48541751c7ee27487bf91fdc79a7b693 211 ProSitePatterns PS01302 Uncharacterized protein family UPF0758 signature. 154 159 - T 28-03-2018 IPR020891 Uncharacterised protein family UPF0758, conserved site ALX04_RS10055 5eb3c69ce432b6aeaf098e4bc04e90ab 153 TIGRFAM TIGR00848 fruA: PTS system, fructose subfamily, IIA component 5 132 1.7E-33 T 28-03-2018 IPR004715 Phosphotransferase system, IIA component fructose subfamily GO:0008982|GO:0009401|GO:0016021 ALX04_RS10055 5eb3c69ce432b6aeaf098e4bc04e90ab 153 SUPERFAMILY SSF55804 2 147 1.7E-35 T 28-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 ALX04_RS10055 5eb3c69ce432b6aeaf098e4bc04e90ab 153 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 3 147 2.0E-34 T 28-03-2018 IPR002178 PTS EIIA type-2 domain ALX04_RS10055 5eb3c69ce432b6aeaf098e4bc04e90ab 153 Gene3D G3DSA:3.40.930.10 1 149 1.7E-34 T 28-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 ALX04_RS06345 f16e63167efb4711e7544300f1ba96e7 324 Pfam PF10978 Protein of unknown function (DUF2785) 130 304 3.3E-57 T 28-03-2018 IPR021247 Protein of unknown function DUF2785 ALX04_RS04125 a646aa9d87dc34c6bf992061574de3c7 129 Pfam PF08349 Protein of unknown function (DUF1722) 12 120 4.9E-23 T 28-03-2018 IPR013560 Domain of unknown function DUF1722 ALX04_RS04125 a646aa9d87dc34c6bf992061574de3c7 129 PIRSF PIRSF032441 1 124 2.4E-51 T 28-03-2018 IPR016996 Uncharacterised conserved protein UCP032441 ALX04_RS09210 5dc45631dcae066b9d2d14f62346f086 555 Pfam PF05598 Transposase domain (DUF772) 45 101 2.2E-11 T 28-03-2018 IPR008490 Transposase InsH, N-terminal ALX04_RS09210 5dc45631dcae066b9d2d14f62346f086 555 Pfam PF01609 Transposase DDE domain 257 508 9.1E-33 T 28-03-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 ALX04_RS09210 5dc45631dcae066b9d2d14f62346f086 555 Gene3D G3DSA:3.90.350.10 230 491 4.3E-8 T 28-03-2018 IPR014736 Transposase, Tn5-like, core ALX04_RS11945 5ebf8739337b93891e4e3317cf9f3be2 248 Pfam PF03883 Peroxide stress protein YaaA 1 235 4.5E-79 T 28-03-2018 IPR005583 Peroxide stress protein YaaA ALX04_RS11945 5ebf8739337b93891e4e3317cf9f3be2 248 Hamap MF_00652 UPF0246 protein YaaA [yaaA]. 1 247 30.804 T 28-03-2018 IPR005583 Peroxide stress protein YaaA ALX04_RS05050 781d1eaace948673cd3e2a1b5e0e1bbd 403 Pfam PF07690 Major Facilitator Superfamily 18 368 6.4E-10 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 ALX04_RS05050 781d1eaace948673cd3e2a1b5e0e1bbd 403 SUPERFAMILY SSF103473 2 402 7.85E-23 T 28-03-2018 IPR020846 Major facilitator superfamily domain ALX04_RS05050 781d1eaace948673cd3e2a1b5e0e1bbd 403 Gene3D G3DSA:1.20.1250.20 1 195 2.2E-13 T 28-03-2018 ALX04_RS05050 781d1eaace948673cd3e2a1b5e0e1bbd 403 Gene3D G3DSA:1.20.1250.20 213 403 1.1E-7 T 28-03-2018 ALX04_RS01970 d915b1a79b9a913648b5594f08cc622c 490 PRINTS PR00131 Glycosyl hydrolase family 1 signature 314 328 4.2E-14 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 ALX04_RS01970 d915b1a79b9a913648b5594f08cc622c 490 PRINTS PR00131 Glycosyl hydrolase family 1 signature 446 458 4.2E-14 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 ALX04_RS01970 d915b1a79b9a913648b5594f08cc622c 490 PRINTS PR00131 Glycosyl hydrolase family 1 signature 379 387 4.2E-14 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 ALX04_RS01970 d915b1a79b9a913648b5594f08cc622c 490 PRINTS PR00131 Glycosyl hydrolase family 1 signature 400 411 4.2E-14 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 ALX04_RS01970 d915b1a79b9a913648b5594f08cc622c 490 PRINTS PR00131 Glycosyl hydrolase family 1 signature 421 438 4.2E-14 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 ALX04_RS01970 d915b1a79b9a913648b5594f08cc622c 490 Pfam PF00232 Glycosyl hydrolase family 1 2 481 1.1E-117 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 ALX04_RS01970 d915b1a79b9a913648b5594f08cc622c 490 Gene3D G3DSA:3.20.20.80 1 489 1.5E-140 T 28-03-2018 ALX04_RS01970 d915b1a79b9a913648b5594f08cc622c 490 SUPERFAMILY SSF51445 1 44 2.67E-150 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily ALX04_RS01970 d915b1a79b9a913648b5594f08cc622c 490 SUPERFAMILY SSF51445 74 483 2.67E-150 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily ALX04_RS01970 d915b1a79b9a913648b5594f08cc622c 490 ProSitePatterns PS00653 Glycosyl hydrolases family 1 N-terminal signature. 7 21 - T 28-03-2018 IPR033132 Glycosyl hydrolases family 1, N-terminal conserved site ALX04_RS15490 b975cac874b69c6bdf8560f977f3ef63 94 Gene3D G3DSA:3.40.30.10 6 94 7.0E-16 T 28-03-2018 ALX04_RS15490 b975cac874b69c6bdf8560f977f3ef63 94 SUPERFAMILY SSF52833 5 93 3.31E-18 T 28-03-2018 IPR012336 Thioredoxin-like fold ALX04_RS15490 b975cac874b69c6bdf8560f977f3ef63 94 Pfam PF00085 Thioredoxin 11 90 2.4E-11 T 28-03-2018 IPR013766 Thioredoxin domain GO:0045454 ALX04_RS03540 1e401dd5e5c02f9b91885e165077aa94 136 Pfam PF08818 Domain of unknown function (DU1801) 30 122 2.9E-8 T 28-03-2018 IPR014922 Domain of unknown function DUF1801 ALX04_RS03540 1e401dd5e5c02f9b91885e165077aa94 136 SUPERFAMILY SSF159888 19 135 1.7E-31 T 28-03-2018 ALX04_RS12070 eff7fb197323d1cc1a226cc475a9b064 454 Pfam PF00324 Amino acid permease 10 441 5.6E-91 T 28-03-2018 IPR004841 Amino acid permease/ SLC12A domain GO:0006810|GO:0016020|GO:0055085 ALX04_RS12070 eff7fb197323d1cc1a226cc475a9b064 454 PIRSF PIRSF006060 1 452 5.2E-60 T 28-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 ALX04_RS12070 eff7fb197323d1cc1a226cc475a9b064 454 ProSitePatterns PS00218 Amino acid permeases signature. 34 64 - T 28-03-2018 IPR004840 Amino acid permease, conserved site GO:0006865|GO:0016021|GO:0055085 ALX04_RS10685 6efc6008425928890c7e5632f52c7f81 113 SUPERFAMILY SSF159121 30 112 4.71E-13 T 28-03-2018 IPR006542 Protein of unknown function DUF1093 ALX04_RS10685 6efc6008425928890c7e5632f52c7f81 113 Pfam PF06486 Protein of unknown function (DUF1093) 31 112 1.4E-11 T 28-03-2018 IPR006542 Protein of unknown function DUF1093 ALX04_RS10685 6efc6008425928890c7e5632f52c7f81 113 TIGRFAM TIGR01655 yxeA_fam: conserved hypothetical protein 12 112 2.3E-12 T 28-03-2018 IPR006542 Protein of unknown function DUF1093 ALX04_RS07100 6acc706c539201cd7bb2ed688a59ab70 447 Pfam PF05167 Uncharacterised ACR (DUF711) 12 411 8.0E-173 T 28-03-2018 IPR007841 Uncharacterised protein family UPF0210 ALX04_RS07100 6acc706c539201cd7bb2ed688a59ab70 447 Hamap MF_01221 UPF0210 protein . 1 447 50.369 T 28-03-2018 IPR007841 Uncharacterised protein family UPF0210 ALX04_RS07100 6acc706c539201cd7bb2ed688a59ab70 447 Gene3D G3DSA:3.20.70.20 13 424 1.2E-179 T 28-03-2018 ALX04_RS07100 6acc706c539201cd7bb2ed688a59ab70 447 SUPERFAMILY SSF51998 3 442 6.41E-176 T 28-03-2018 ALX04_RS09625 06fcce38b522ef474dc19afbb46f550d 314 SUPERFAMILY SSF56672 142 221 4.8E-7 T 28-03-2018 ALX04_RS09625 06fcce38b522ef474dc19afbb46f550d 314 PRINTS PR00866 RNA-dependent DNA-polymerase (msDNA) signature 46 58 2.0E-17 T 28-03-2018 IPR000123 RNA-directed DNA polymerase (reverse transcriptase), msDNA GO:0003723|GO:0003964|GO:0006278 ALX04_RS09625 06fcce38b522ef474dc19afbb46f550d 314 PRINTS PR00866 RNA-dependent DNA-polymerase (msDNA) signature 76 90 2.0E-17 T 28-03-2018 IPR000123 RNA-directed DNA polymerase (reverse transcriptase), msDNA GO:0003723|GO:0003964|GO:0006278 ALX04_RS09625 06fcce38b522ef474dc19afbb46f550d 314 PRINTS PR00866 RNA-dependent DNA-polymerase (msDNA) signature 178 189 2.0E-17 T 28-03-2018 IPR000123 RNA-directed DNA polymerase (reverse transcriptase), msDNA GO:0003723|GO:0003964|GO:0006278 ALX04_RS09625 06fcce38b522ef474dc19afbb46f550d 314 PRINTS PR00866 RNA-dependent DNA-polymerase (msDNA) signature 92 110 2.0E-17 T 28-03-2018 IPR000123 RNA-directed DNA polymerase (reverse transcriptase), msDNA GO:0003723|GO:0003964|GO:0006278 ALX04_RS09625 06fcce38b522ef474dc19afbb46f550d 314 PRINTS PR00866 RNA-dependent DNA-polymerase (msDNA) signature 145 158 2.0E-17 T 28-03-2018 IPR000123 RNA-directed DNA polymerase (reverse transcriptase), msDNA GO:0003723|GO:0003964|GO:0006278 ALX04_RS09625 06fcce38b522ef474dc19afbb46f550d 314 PRINTS PR00866 RNA-dependent DNA-polymerase (msDNA) signature 232 238 2.0E-17 T 28-03-2018 IPR000123 RNA-directed DNA polymerase (reverse transcriptase), msDNA GO:0003723|GO:0003964|GO:0006278 ALX04_RS09625 06fcce38b522ef474dc19afbb46f550d 314 Pfam PF00078 Reverse transcriptase (RNA-dependent DNA polymerase) 42 235 4.5E-15 T 28-03-2018 IPR000477 Reverse transcriptase domain ALX04_RS09625 06fcce38b522ef474dc19afbb46f550d 314 Gene3D G3DSA:3.30.70.270 68 236 9.5E-15 T 28-03-2018 ALX04_RS08695 684b32b8b2f61bb7f71404809f1fed86 147 Pfam PF00582 Universal stress protein family 9 147 5.4E-27 T 28-03-2018 IPR006016 UspA GO:0006950 ALX04_RS08695 684b32b8b2f61bb7f71404809f1fed86 147 PIRSF PIRSF006276 4 147 1.1E-18 T 28-03-2018 IPR006015 Universal stress protein A ALX04_RS08695 684b32b8b2f61bb7f71404809f1fed86 147 PRINTS PR01438 Universal stress protein signature 108 120 1.7E-9 T 28-03-2018 IPR006015 Universal stress protein A ALX04_RS08695 684b32b8b2f61bb7f71404809f1fed86 147 PRINTS PR01438 Universal stress protein signature 125 147 1.7E-9 T 28-03-2018 IPR006015 Universal stress protein A ALX04_RS08695 684b32b8b2f61bb7f71404809f1fed86 147 PRINTS PR01438 Universal stress protein signature 9 27 1.7E-9 T 28-03-2018 IPR006015 Universal stress protein A ALX04_RS08695 684b32b8b2f61bb7f71404809f1fed86 147 SUPERFAMILY SSF52402 9 147 1.09E-28 T 28-03-2018 ALX04_RS08695 684b32b8b2f61bb7f71404809f1fed86 147 Gene3D G3DSA:3.40.50.620 1 147 6.6E-30 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold ALX04_RS03830 fac02d57c692f7307fa93354c3e28627 352 TIGRFAM TIGR03858 LLM_2I7G: probable oxidoreductase, LLM family 8 341 7.8E-147 T 28-03-2018 IPR022290 Conserved hypothetical protein CHP03858, luciferase-like monooxygenase, putative ALX04_RS03830 fac02d57c692f7307fa93354c3e28627 352 Gene3D G3DSA:3.20.20.30 2 351 2.7E-68 T 28-03-2018 ALX04_RS03830 fac02d57c692f7307fa93354c3e28627 352 Pfam PF00296 Luciferase-like monooxygenase 22 257 2.8E-40 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 ALX04_RS03830 fac02d57c692f7307fa93354c3e28627 352 SUPERFAMILY SSF51679 8 341 5.1E-68 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 ALX04_RS06180 28b9bff36ef9461953ec51a6742c0ec4 281 TIGRFAM TIGR00219 mreC: rod shape-determining protein MreC 10 278 2.3E-49 T 28-03-2018 IPR007221 Rod shape-determining protein MreC GO:0008360 ALX04_RS06180 28b9bff36ef9461953ec51a6742c0ec4 281 PIRSF PIRSF038471 1 281 5.5E-74 T 28-03-2018 IPR007221 Rod shape-determining protein MreC GO:0008360 ALX04_RS06180 28b9bff36ef9461953ec51a6742c0ec4 281 Pfam PF04085 rod shape-determining protein MreC 126 279 2.9E-41 T 28-03-2018 IPR007221 Rod shape-determining protein MreC GO:0008360 ALX04_RS08725 2f879c12bf7aef535805dccf6fa54da2 288 Pfam PF12541 Protein of unknown function (DUF3737) 2 276 2.3E-126 T 28-03-2018 IPR022208 Protein of unknown function DUF3737 ALX04_RS08725 2f879c12bf7aef535805dccf6fa54da2 288 SUPERFAMILY SSF51126 30 58 1.08E-17 T 28-03-2018 IPR011050 Pectin lyase fold/virulence factor ALX04_RS08725 2f879c12bf7aef535805dccf6fa54da2 288 SUPERFAMILY SSF51126 86 264 1.08E-17 T 28-03-2018 IPR011050 Pectin lyase fold/virulence factor ALX04_RS08725 2f879c12bf7aef535805dccf6fa54da2 288 Gene3D G3DSA:2.160.20.10 6 282 8.5E-13 T 28-03-2018 IPR012334 Pectin lyase fold ALX04_RS09100 080fe26e3a13245b0dd324f757239076 259 Pfam PF00005 ABC transporter 22 185 1.5E-26 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 ALX04_RS09100 080fe26e3a13245b0dd324f757239076 259 SMART SM00382 30 231 1.2E-7 T 28-03-2018 IPR003593 AAA+ ATPase domain ALX04_RS09100 080fe26e3a13245b0dd324f757239076 259 Gene3D G3DSA:3.40.50.300 2 256 2.1E-51 T 28-03-2018 ALX04_RS09100 080fe26e3a13245b0dd324f757239076 259 SUPERFAMILY SSF52540 5 256 6.88E-56 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase ALX04_RS09100 080fe26e3a13245b0dd324f757239076 259 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 236 257 2.4E-9 T 28-03-2018 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal ALX04_RS00915 453089cfc9b86dd29bf09bb9b8877f00 294 Pfam PF06028 Alpha/beta hydrolase of unknown function (DUF915) 47 277 8.5E-61 T 28-03-2018 IPR010315 Protein of unknown function DUF915, hydrolase-like ALX04_RS00915 453089cfc9b86dd29bf09bb9b8877f00 294 SUPERFAMILY SSF53474 117 242 4.81E-13 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold ALX04_RS00915 453089cfc9b86dd29bf09bb9b8877f00 294 SUPERFAMILY SSF53474 52 79 4.81E-13 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold ALX04_RS00915 453089cfc9b86dd29bf09bb9b8877f00 294 Gene3D G3DSA:3.40.50.1820 47 290 1.4E-21 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold ALX04_RS04690 d95928ebf9293e6ea7f0490f9b1b6483 79 Gene3D G3DSA:1.10.287.540 4 56 4.2E-23 T 28-03-2018 ALX04_RS04690 d95928ebf9293e6ea7f0490f9b1b6483 79 Pfam PF05979 Bacterial protein of unknown function (DUF896) 5 68 4.9E-30 T 28-03-2018 IPR009242 Protein of unknown function DUF896 ALX04_RS04690 d95928ebf9293e6ea7f0490f9b1b6483 79 SUPERFAMILY SSF158221 2 42 1.44E-13 T 28-03-2018 ALX04_RS04690 d95928ebf9293e6ea7f0490f9b1b6483 79 Hamap MF_01103 UPF0291 protein . 2 60 16.225 T 28-03-2018 IPR009242 Protein of unknown function DUF896 ALX04_RS12100 173cec9fd87aa27b14122a06188815b9 225 TIGRFAM TIGR01866 cas_Csn2: CRISPR type II-A/NMEMI-associated protein Csn2 2 221 8.9E-39 T 28-03-2018 IPR010146 CRISPR-associated protein, Csn2-type ALX04_RS12100 173cec9fd87aa27b14122a06188815b9 225 Pfam PF09711 CRISPR-associated protein (Cas_Csn2) 67 217 2.5E-7 T 28-03-2018 IPR010146 CRISPR-associated protein, Csn2-type ALX04_RS02320 bd6b6d0c30129368c4083e83373bb102 171 Pfam PF03477 ATP cone domain 50 136 2.8E-18 T 28-03-2018 IPR005144 ATP-cone domain Reactome: R-HSA-499943 ALX04_RS02320 bd6b6d0c30129368c4083e83373bb102 171 Hamap MF_00440 Transcriptional repressor NrdR [nrdR]. 1 154 85.225 T 28-03-2018 IPR003796 Ribonucleotide reductase regulator NrdR-like GO:0008270|GO:0045892 ALX04_RS02320 bd6b6d0c30129368c4083e83373bb102 171 TIGRFAM TIGR00244 TIGR00244: transcriptional regulator NrdR 1 146 9.3E-62 T 28-03-2018 IPR003796 Ribonucleotide reductase regulator NrdR-like GO:0008270|GO:0045892 ALX04_RS01060 27c49304af2c239906ac7cb7aef26d8f 249 SUPERFAMILY SSF52266 139 246 3.66E-8 T 28-03-2018 IPR013830 SGNH hydrolase-type esterase domain ALX04_RS01060 27c49304af2c239906ac7cb7aef26d8f 249 Gene3D G3DSA:3.40.50.1110 17 247 2.9E-7 T 28-03-2018 ALX04_RS08375 d5b255374d52eb82128bb1035ede7526 179 Pfam PF01872 RibD C-terminal domain 3 167 2.8E-17 T 28-03-2018 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 ALX04_RS08375 d5b255374d52eb82128bb1035ede7526 179 Gene3D G3DSA:3.40.430.10 1 176 2.1E-36 T 28-03-2018 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 ALX04_RS08375 d5b255374d52eb82128bb1035ede7526 179 SUPERFAMILY SSF53597 3 175 1.44E-32 T 28-03-2018 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 ALX04_RS07715 e19d343f1560c666a0b363c67033a05a 530 Pfam PF00999 Sodium/hydrogen exchanger family 9 397 1.7E-32 T 28-03-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 ALX04_RS04345 5d5a4abc6dc583894c68c37a4be6e1b6 299 Gene3D G3DSA:3.30.930.10 1 208 2.6E-80 T 28-03-2018 ALX04_RS04345 5d5a4abc6dc583894c68c37a4be6e1b6 299 Gene3D G3DSA:1.20.58.180 210 286 9.5E-34 T 28-03-2018 ALX04_RS04345 5d5a4abc6dc583894c68c37a4be6e1b6 299 Hamap MF_00254 Glycine--tRNA ligase alpha subunit [glyQ]. 5 285 56.602 T 28-03-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 ALX04_RS04345 5d5a4abc6dc583894c68c37a4be6e1b6 299 SUPERFAMILY SSF55681 6 284 4.97E-127 T 28-03-2018 ALX04_RS04345 5d5a4abc6dc583894c68c37a4be6e1b6 299 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 245 261 1.6E-63 T 28-03-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 ALX04_RS04345 5d5a4abc6dc583894c68c37a4be6e1b6 299 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 59 74 1.6E-63 T 28-03-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 ALX04_RS04345 5d5a4abc6dc583894c68c37a4be6e1b6 299 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 160 175 1.6E-63 T 28-03-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 ALX04_RS04345 5d5a4abc6dc583894c68c37a4be6e1b6 299 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 80 100 1.6E-63 T 28-03-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 ALX04_RS04345 5d5a4abc6dc583894c68c37a4be6e1b6 299 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 111 135 1.6E-63 T 28-03-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 ALX04_RS04345 5d5a4abc6dc583894c68c37a4be6e1b6 299 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 137 157 1.6E-63 T 28-03-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 ALX04_RS04345 5d5a4abc6dc583894c68c37a4be6e1b6 299 TIGRFAM TIGR00388 glyQ: glycine--tRNA ligase, alpha subunit 7 292 3.8E-151 T 28-03-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 ALX04_RS04345 5d5a4abc6dc583894c68c37a4be6e1b6 299 Pfam PF02091 Glycyl-tRNA synthetase alpha subunit 7 284 3.7E-144 T 28-03-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 ALX04_RS00650 6377bce3c0e2d1a3450874dbd6708a00 290 SUPERFAMILY SSF81345 10 262 2.22E-44 T 28-03-2018 IPR029022 ABC transporter, BtuC-like ALX04_RS00650 6377bce3c0e2d1a3450874dbd6708a00 290 Pfam PF00950 ABC 3 transport family 13 268 1.9E-82 T 28-03-2018 IPR001626 ABC transporter, TroCD-like GO:0005887|GO:0042626|GO:0043190|GO:0055085 ALX04_RS00650 6377bce3c0e2d1a3450874dbd6708a00 290 Gene3D G3DSA:1.10.3470.10 8 275 1.2E-30 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like ALX04_RS02475 34f94690636c83b298f73e733f7971e8 322 Pfam PF01040 UbiA prenyltransferase family 29 290 3.8E-18 T 28-03-2018 IPR000537 UbiA prenyltransferase family GO:0016021|GO:0016765 ALX04_RS09925 dc99078b427bc66be5d123d75bc40a1a 277 Pfam PF06028 Alpha/beta hydrolase of unknown function (DUF915) 44 276 1.6E-30 T 28-03-2018 IPR010315 Protein of unknown function DUF915, hydrolase-like ALX04_RS09925 dc99078b427bc66be5d123d75bc40a1a 277 Gene3D G3DSA:3.40.50.1820 31 252 1.7E-8 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold ALX04_RS01980 f0aaa3e4b29e7a7c02238a4a38d01792 203 Pfam PF03734 L,D-transpeptidase catalytic domain 81 202 2.1E-18 T 28-03-2018 IPR005490 L,D-transpeptidase catalytic domain GO:0016740 ALX04_RS01980 f0aaa3e4b29e7a7c02238a4a38d01792 203 SUPERFAMILY SSF141523 76 202 4.71E-27 T 28-03-2018 ALX04_RS01980 f0aaa3e4b29e7a7c02238a4a38d01792 203 Gene3D G3DSA:2.40.440.10 72 203 9.3E-28 T 28-03-2018 ALX04_RS09140 cdff0a084f007ce3311c19a9a307188b 530 TIGRFAM TIGR01197 nramp: metal ion transporter, metal ion (Mn2+/Fe2+) transporter (Nramp) family 42 435 9.3E-102 T 28-03-2018 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-425410 ALX04_RS09140 cdff0a084f007ce3311c19a9a307188b 530 PRINTS PR00447 Natural resistance-associated macrophage protein signature 347 366 2.0E-44 T 28-03-2018 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-425410 ALX04_RS09140 cdff0a084f007ce3311c19a9a307188b 530 PRINTS PR00447 Natural resistance-associated macrophage protein signature 149 168 2.0E-44 T 28-03-2018 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-425410 ALX04_RS09140 cdff0a084f007ce3311c19a9a307188b 530 PRINTS PR00447 Natural resistance-associated macrophage protein signature 121 147 2.0E-44 T 28-03-2018 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-425410 ALX04_RS09140 cdff0a084f007ce3311c19a9a307188b 530 PRINTS PR00447 Natural resistance-associated macrophage protein signature 232 255 2.0E-44 T 28-03-2018 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-425410 ALX04_RS09140 cdff0a084f007ce3311c19a9a307188b 530 PRINTS PR00447 Natural resistance-associated macrophage protein signature 375 392 2.0E-44 T 28-03-2018 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-425410 ALX04_RS09140 cdff0a084f007ce3311c19a9a307188b 530 Pfam PF01566 Natural resistance-associated macrophage protein 62 444 3.6E-112 T 28-03-2018 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-425410 ALX04_RS07875 441b34ace3d2ba00171076b080f4a38c 442 Pfam PF00535 Glycosyl transferase family 2 68 239 1.3E-28 T 28-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 ALX04_RS07875 441b34ace3d2ba00171076b080f4a38c 442 SUPERFAMILY SSF53448 59 343 2.51E-48 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases ALX04_RS07875 441b34ace3d2ba00171076b080f4a38c 442 Gene3D G3DSA:3.90.550.10 41 323 5.2E-47 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases ALX04_RS06910 03e34dcaa1ada2476de68365f984ae02 66 Gene3D G3DSA:1.20.1560.10 2 65 3.4E-4 T 28-03-2018 ALX04_RS04885 85474069c3a54393fe9cacbdeaddcf83 142 TIGRFAM TIGR01636 phage_rinA: phage transcriptional regulator, RinA family 2 137 2.9E-28 T 28-03-2018 IPR006523 Transcription activator RinA ALX04_RS13340 964d8d3788150aa266a75393f5afc7e7 57 Pfam PF03047 COMC family 1 22 6.6E-5 T 28-03-2018 IPR004288 Competence protein, ComC GO:0005186 ALX04_RS10820 4a6b7d29996213d871125cf15caeac55 213 Gene3D G3DSA:3.40.50.1110 19 213 2.3E-16 T 28-03-2018 ALX04_RS10820 4a6b7d29996213d871125cf15caeac55 213 SUPERFAMILY SSF52266 24 205 9.92E-18 T 28-03-2018 IPR013830 SGNH hydrolase-type esterase domain ALX04_RS10820 4a6b7d29996213d871125cf15caeac55 213 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 30 152 7.0E-12 T 28-03-2018 IPR013830 SGNH hydrolase-type esterase domain ALX04_RS00235 c12a3855fe4b8cb507eb97dd3c688cb0 249 Pfam PF06738 Putative threonine/serine exporter 12 248 6.1E-68 T 28-03-2018 IPR010619 Putative threonine/serine exporter ALX04_RS04800 3d06e57fff61bbcd5e56b42cc63b6e71 1801 Gene3D G3DSA:1.20.120.330 29 191 1.0E-4 T 28-03-2018 ALX04_RS04800 3d06e57fff61bbcd5e56b42cc63b6e71 1801 Pfam PF10145 Phage-related minor tail protein 312 521 8.7E-38 T 28-03-2018 IPR010090 Phage tail tape measure protein ALX04_RS04800 3d06e57fff61bbcd5e56b42cc63b6e71 1801 SUPERFAMILY SSF57997 30 245 1.31E-6 T 28-03-2018 ALX04_RS04800 3d06e57fff61bbcd5e56b42cc63b6e71 1801 TIGRFAM TIGR01760 tape_meas_TP901: phage tail tape measure protein, TP901 family, core region 301 605 1.6E-42 T 28-03-2018 IPR010090 Phage tail tape measure protein ALX04_RS03965 a94799cfc14de7f74b6804c55c17187a 255 Hamap MF_01805 Segregation and condensation protein A [scpA]. 9 248 25.048 T 28-03-2018 IPR003768 Segregation and condensation protein A ALX04_RS03965 a94799cfc14de7f74b6804c55c17187a 255 Gene3D G3DSA:1.10.10.580 180 245 2.6E-12 T 28-03-2018 ALX04_RS03965 a94799cfc14de7f74b6804c55c17187a 255 Pfam PF02616 Segregation and condensation protein ScpA 26 243 7.9E-41 T 28-03-2018 IPR003768 Segregation and condensation protein A ALX04_RS05600 66e1ccf2a1c037f4b0c808e41ef3e656 284 PIRSF PIRSF018249 3 284 8.2E-92 T 28-03-2018 IPR016718 rRNA (guanine-N1-)-methyltransferase A, predicted GO:0008168 ALX04_RS05600 66e1ccf2a1c037f4b0c808e41ef3e656 284 Pfam PF13649 Methyltransferase domain 97 182 1.7E-7 T 28-03-2018 ALX04_RS05600 66e1ccf2a1c037f4b0c808e41ef3e656 284 SUPERFAMILY SSF53335 36 274 2.41E-25 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase ALX04_RS05600 66e1ccf2a1c037f4b0c808e41ef3e656 284 Gene3D G3DSA:3.40.50.150 16 284 7.0E-29 T 28-03-2018 ALX04_RS00870 1f957371107b8e80d238c29f213ed089 391 PIRSF PIRSF012509 2 386 5.1E-148 T 28-03-2018 IPR011426 CamS sex pheromone cAM373 ALX04_RS00870 1f957371107b8e80d238c29f213ed089 391 Pfam PF07537 CamS sex pheromone cAM373 precursor 65 376 4.8E-125 T 28-03-2018 IPR011426 CamS sex pheromone cAM373 ALX04_RS00870 1f957371107b8e80d238c29f213ed089 391 Gene3D G3DSA:3.10.570.10 41 386 5.0E-130 T 28-03-2018 ALX04_RS04730 11092bdaadac1aa80215cba43f826022 190 SUPERFAMILY SSF48295 104 158 4.03E-10 T 28-03-2018 IPR010921 Trp repressor/replication initiator GO:0043565 ALX04_RS04730 11092bdaadac1aa80215cba43f826022 190 Gene3D G3DSA:1.10.10.10 98 180 1.1E-6 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS13470 feac093684dacbc4f638d2f5d267caa8 478 ProSitePatterns PS00572 Glycosyl hydrolases family 1 active site. 371 379 - T 28-03-2018 IPR018120 Glycoside hydrolase family 1, active site ALX04_RS13470 feac093684dacbc4f638d2f5d267caa8 478 Pfam PF00232 Glycosyl hydrolase family 1 7 474 8.3E-132 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 ALX04_RS13470 feac093684dacbc4f638d2f5d267caa8 478 Gene3D G3DSA:3.20.20.80 1 478 2.9E-155 T 28-03-2018 ALX04_RS13470 feac093684dacbc4f638d2f5d267caa8 478 SUPERFAMILY SSF51445 7 470 4.83E-165 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily ALX04_RS13470 feac093684dacbc4f638d2f5d267caa8 478 PRINTS PR00131 Glycosyl hydrolase family 1 signature 439 451 5.8E-17 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 ALX04_RS13470 feac093684dacbc4f638d2f5d267caa8 478 PRINTS PR00131 Glycosyl hydrolase family 1 signature 392 403 5.8E-17 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 ALX04_RS13470 feac093684dacbc4f638d2f5d267caa8 478 PRINTS PR00131 Glycosyl hydrolase family 1 signature 308 322 5.8E-17 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 ALX04_RS13470 feac093684dacbc4f638d2f5d267caa8 478 PRINTS PR00131 Glycosyl hydrolase family 1 signature 371 379 5.8E-17 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 ALX04_RS13470 feac093684dacbc4f638d2f5d267caa8 478 PRINTS PR00131 Glycosyl hydrolase family 1 signature 414 431 5.8E-17 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 ALX04_RS13470 feac093684dacbc4f638d2f5d267caa8 478 ProSitePatterns PS00653 Glycosyl hydrolases family 1 N-terminal signature. 12 26 - T 28-03-2018 IPR033132 Glycosyl hydrolases family 1, N-terminal conserved site ALX04_RS07350 50b274455b472be39bb4de1cf60425c7 171 Gene3D G3DSA:3.30.530.20 15 171 2.9E-6 T 28-03-2018 IPR023393 START-like domain ALX04_RS01445 d9a906d109079cb9f648f8668d33b80d 78 PIRSF PIRSF037356 1 76 1.3E-32 T 28-03-2018 IPR014904 Protein of unknown function DUF1797 ALX04_RS01445 d9a906d109079cb9f648f8668d33b80d 78 Pfam PF08796 Protein of unknown function (DUF1797) 9 75 2.9E-29 T 28-03-2018 IPR014904 Protein of unknown function DUF1797 ALX04_RS01445 d9a906d109079cb9f648f8668d33b80d 78 SUPERFAMILY SSF143567 4 75 1.28E-24 T 28-03-2018 ALX04_RS11630 e2b0a697a40ca0cf47820d94cc8dff81 407 Gene3D G3DSA:1.20.1250.20 194 407 1.8E-25 T 28-03-2018 ALX04_RS11630 e2b0a697a40ca0cf47820d94cc8dff81 407 Gene3D G3DSA:1.20.1250.20 4 182 6.2E-20 T 28-03-2018 ALX04_RS11630 e2b0a697a40ca0cf47820d94cc8dff81 407 SUPERFAMILY SSF103473 10 383 7.06E-47 T 28-03-2018 IPR020846 Major facilitator superfamily domain ALX04_RS11630 e2b0a697a40ca0cf47820d94cc8dff81 407 Pfam PF07690 Major Facilitator Superfamily 13 292 3.5E-19 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 ALX04_RS02400 b077c4ccce159619b561f3cf2969b757 378 SUPERFAMILY SSF52540 76 255 4.6E-30 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase ALX04_RS02400 b077c4ccce159619b561f3cf2969b757 378 TIGRFAM TIGR03597 GTPase_YqeH: ribosome biogenesis GTPase YqeH 11 375 4.7E-150 T 28-03-2018 IPR019988 GTP-binding protein, riobosome biogenesis, YqeH ALX04_RS02400 b077c4ccce159619b561f3cf2969b757 378 Gene3D G3DSA:3.40.50.300 66 234 5.6E-31 T 28-03-2018 ALX04_RS02400 b077c4ccce159619b561f3cf2969b757 378 Pfam PF01926 50S ribosome-binding GTPase 173 234 3.6E-13 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 ALX04_RS12985 62f5c6c4530bc226c35d8c250bacd9ac 161 SUPERFAMILY SSF55729 1 146 3.72E-20 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase ALX04_RS12985 62f5c6c4530bc226c35d8c250bacd9ac 161 Gene3D G3DSA:3.40.630.30 1 156 3.7E-23 T 28-03-2018 ALX04_RS12985 62f5c6c4530bc226c35d8c250bacd9ac 161 Pfam PF00583 Acetyltransferase (GNAT) family 18 138 2.6E-12 T 28-03-2018 IPR000182 GNAT domain GO:0008080 ALX04_RS09125 2bc2650b5f610821e6b104d4bfda8b6c 266 Pfam PF00413 Matrixin 191 262 5.5E-13 T 28-03-2018 IPR001818 Peptidase M10, metallopeptidase GO:0004222|GO:0006508|GO:0008270|GO:0031012 ALX04_RS09125 2bc2650b5f610821e6b104d4bfda8b6c 266 SMART SM00235 112 264 0.0039 T 28-03-2018 IPR006026 Peptidase, metallopeptidase GO:0006508|GO:0008237|GO:0008270 ALX04_RS09125 2bc2650b5f610821e6b104d4bfda8b6c 266 SUPERFAMILY SSF55486 117 265 9.12E-23 T 28-03-2018 ALX04_RS09125 2bc2650b5f610821e6b104d4bfda8b6c 266 Gene3D G3DSA:3.40.390.10 33 266 9.5E-23 T 28-03-2018 IPR024079 Metallopeptidase, catalytic domain GO:0008237 ALX04_RS08980 8eb3ea71833ca1c6924d3689a6f13918 249 PRINTS PR00111 Alpha/beta hydrolase fold signature 120 133 3.3E-6 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 ALX04_RS08980 8eb3ea71833ca1c6924d3689a6f13918 249 PRINTS PR00111 Alpha/beta hydrolase fold signature 106 119 3.3E-6 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 ALX04_RS08980 8eb3ea71833ca1c6924d3689a6f13918 249 PRINTS PR00111 Alpha/beta hydrolase fold signature 59 74 3.3E-6 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 ALX04_RS08980 8eb3ea71833ca1c6924d3689a6f13918 249 SUPERFAMILY SSF53474 182 248 6.56E-44 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold ALX04_RS08980 8eb3ea71833ca1c6924d3689a6f13918 249 SUPERFAMILY SSF53474 6 139 6.56E-44 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold ALX04_RS08980 8eb3ea71833ca1c6924d3689a6f13918 249 Gene3D G3DSA:3.40.50.1820 2 249 3.7E-43 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold ALX04_RS08980 8eb3ea71833ca1c6924d3689a6f13918 249 Pfam PF12146 Serine aminopeptidase, S33 27 142 2.4E-18 T 28-03-2018 IPR022742 Serine aminopeptidase, S33 ALX04_RS01130 31359469138a030ea96163deff27f4af 269 Pfam PF00535 Glycosyl transferase family 2 21 115 4.3E-7 T 28-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 ALX04_RS01130 31359469138a030ea96163deff27f4af 269 SUPERFAMILY SSF53448 22 244 5.51E-16 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases ALX04_RS01130 31359469138a030ea96163deff27f4af 269 Gene3D G3DSA:3.90.550.10 7 217 4.2E-11 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases ALX04_RS08790 c1519d4c4047bfbfde7de066da652f2d 175 Pfam PF13302 Acetyltransferase (GNAT) domain 8 142 4.5E-25 T 28-03-2018 IPR000182 GNAT domain GO:0008080 ALX04_RS08790 c1519d4c4047bfbfde7de066da652f2d 175 Gene3D G3DSA:3.40.630.30 1 174 9.4E-28 T 28-03-2018 ALX04_RS08790 c1519d4c4047bfbfde7de066da652f2d 175 SUPERFAMILY SSF55729 3 163 3.36E-34 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase ALX04_RS09025 71ee3b5303dcf50509a14caf5d7cc962 100 Gene3D G3DSA:1.10.10.10 14 99 7.6E-5 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS09025 71ee3b5303dcf50509a14caf5d7cc962 100 SUPERFAMILY SSF46785 11 96 3.03E-10 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS09025 71ee3b5303dcf50509a14caf5d7cc962 100 Pfam PF01638 HxlR-like helix-turn-helix 16 96 1.2E-5 T 28-03-2018 IPR002577 Helix-turn-helix, HxlR type ALX04_RS14590 239f7902d60cb49d54d92e1c575fe612 103 Pfam PF04024 PspC domain 8 63 3.1E-17 T 28-03-2018 IPR007168 Phage shock protein, PspC, N-terminal ALX04_RS09760 c6282c177b83a1afb172f57652a12a1e 240 Pfam PF00753 Metallo-beta-lactamase superfamily 22 212 4.0E-26 T 28-03-2018 IPR001279 Metallo-beta-lactamase ALX04_RS09760 c6282c177b83a1afb172f57652a12a1e 240 Gene3D G3DSA:3.60.15.10 5 235 5.6E-32 T 28-03-2018 IPR001279 Metallo-beta-lactamase ALX04_RS09760 c6282c177b83a1afb172f57652a12a1e 240 SUPERFAMILY SSF56281 22 234 1.1E-39 T 28-03-2018 IPR001279 Metallo-beta-lactamase ALX04_RS09760 c6282c177b83a1afb172f57652a12a1e 240 SMART SM00849 24 216 1.5E-22 T 28-03-2018 IPR001279 Metallo-beta-lactamase ALX04_RS02890 eba6872bb31f4b45765b5934d9480ad4 90 Hamap MF_00385 30S ribosomal protein S16 [rpsP]. 2 77 25.371 T 28-03-2018 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 ALX04_RS02890 eba6872bb31f4b45765b5934d9480ad4 90 Gene3D G3DSA:3.30.1320.10 2 85 1.4E-35 T 28-03-2018 IPR023803 Ribosomal protein S16 domain Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 ALX04_RS02890 eba6872bb31f4b45765b5934d9480ad4 90 SUPERFAMILY SSF54565 3 86 2.62E-35 T 28-03-2018 IPR023803 Ribosomal protein S16 domain Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 ALX04_RS02890 eba6872bb31f4b45765b5934d9480ad4 90 TIGRFAM TIGR00002 S16: ribosomal protein bS16 3 80 1.2E-36 T 28-03-2018 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 ALX04_RS02890 eba6872bb31f4b45765b5934d9480ad4 90 Pfam PF00886 Ribosomal protein S16 9 67 9.4E-26 T 28-03-2018 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 ALX04_RS13075 7f3c73c4e390ece9a24185ab504c67ee 271 Pfam PF01061 ABC-2 type transporter 19 227 5.2E-19 T 28-03-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 ALX04_RS15810 8e5ba7ba3fea465bca5e520f9f3ac541 674 SUPERFAMILY SSF53756 406 639 1.57E-17 T 28-03-2018 ALX04_RS15810 8e5ba7ba3fea465bca5e520f9f3ac541 674 Pfam PF04464 CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase 299 667 1.4E-121 T 28-03-2018 IPR007554 CDP-glycerol glycerophosphotransferase GO:0016020|GO:0047355 ALX04_RS11905 77ae9a32ddd58888283ee5e54aad1f12 224 SUPERFAMILY SSF52317 1 224 3.82E-67 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like ALX04_RS11905 77ae9a32ddd58888283ee5e54aad1f12 224 Gene3D G3DSA:3.40.50.880 1 224 2.0E-45 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like ALX04_RS11905 77ae9a32ddd58888283ee5e54aad1f12 224 Pfam PF01965 DJ-1/PfpI family 27 222 8.5E-10 T 28-03-2018 IPR002818 DJ-1/PfpI ALX04_RS04505 b0cd27da5f39a5691945c658210e2616 49 Pfam PF12459 D-Ala-teichoic acid biosynthesis protein 8 49 1.4E-22 T 28-03-2018 IPR021008 Protein of unknown function DUF3687 ALX04_RS08785 97c53148b22200318b16242ac282e3ab 181 Pfam PF13302 Acetyltransferase (GNAT) domain 5 148 1.0E-12 T 28-03-2018 IPR000182 GNAT domain GO:0008080 ALX04_RS08785 97c53148b22200318b16242ac282e3ab 181 SUPERFAMILY SSF55729 1 178 3.15E-23 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase ALX04_RS08785 97c53148b22200318b16242ac282e3ab 181 Gene3D G3DSA:3.40.630.30 1 180 6.9E-23 T 28-03-2018 ALX04_RS03125 f0eeca95876bde4fa7f0542dae4e2529 164 Pfam PF13787 Protein of unknown function with HXXEE motif 8 118 2.0E-16 T 28-03-2018 IPR025671 Protein of unknown function with HXXEE motif ALX04_RS08240 4b0184e0ab45d047ce10706f4f44c586 249 Gene3D G3DSA:3.20.20.70 1 245 3.8E-36 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 ALX04_RS08240 4b0184e0ab45d047ce10706f4f44c586 249 SUPERFAMILY SSF51569 2 243 2.23E-35 T 28-03-2018 ALX04_RS08240 4b0184e0ab45d047ce10706f4f44c586 249 Pfam PF01487 Type I 3-dehydroquinase 21 240 5.8E-33 T 28-03-2018 IPR001381 3-dehydroquinate dehydratase type I GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 ALX04_RS11240 c7d98bfc8dc361ad32dd6e03df512ede 98 Pfam PF02302 PTS system, Lactose/Cellobiose specific IIB subunit 4 82 1.5E-9 T 28-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 ALX04_RS11240 c7d98bfc8dc361ad32dd6e03df512ede 98 Gene3D G3DSA:3.40.50.2300 1 95 1.8E-15 T 28-03-2018 ALX04_RS11240 c7d98bfc8dc361ad32dd6e03df512ede 98 SUPERFAMILY SSF52794 1 91 3.03E-16 T 28-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 ALX04_RS08450 55ab53536f6a2e8419f8d2e38af12d70 347 SUPERFAMILY SSF54106 28 71 1.18E-7 T 28-03-2018 IPR018392 LysM domain ALX04_RS08450 55ab53536f6a2e8419f8d2e38af12d70 347 SMART SM00257 28 72 9.7E-12 T 28-03-2018 IPR018392 LysM domain ALX04_RS08450 55ab53536f6a2e8419f8d2e38af12d70 347 Gene3D G3DSA:3.10.350.10 22 77 4.9E-13 T 28-03-2018 ALX04_RS08450 55ab53536f6a2e8419f8d2e38af12d70 347 Pfam PF01476 LysM domain 29 71 9.8E-11 T 28-03-2018 IPR018392 LysM domain ALX04_RS09110 27e2783075e6f7001459c78830fd1414 292 Pfam PF02653 Branched-chain amino acid transport system / permease component 8 276 4.0E-49 T 28-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 ALX04_RS09110 27e2783075e6f7001459c78830fd1414 292 Gene3D G3DSA:1.10.3470.10 1 287 8.2E-55 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like ALX04_RS03080 92f86b2c467da67e0cc7edc983f20c47 183 SUPERFAMILY SSF56214 22 72 3.49E-6 T 28-03-2018 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 ALX04_RS03080 92f86b2c467da67e0cc7edc983f20c47 183 Gene3D G3DSA:3.90.470.20 87 177 5.1E-13 T 28-03-2018 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 ALX04_RS03080 92f86b2c467da67e0cc7edc983f20c47 183 Gene3D G3DSA:3.90.470.20 9 86 3.0E-10 T 28-03-2018 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 ALX04_RS03080 92f86b2c467da67e0cc7edc983f20c47 183 Pfam PF01648 4'-phosphopantetheinyl transferase superfamily 80 151 1.2E-13 T 28-03-2018 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 ALX04_RS03080 92f86b2c467da67e0cc7edc983f20c47 183 SUPERFAMILY SSF56214 79 156 2.88E-19 T 28-03-2018 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 ALX04_RS11270 88c2a36c44776cd95300ee4e7937f33b 98 Gene3D G3DSA:3.40.50.2300 1 93 1.9E-22 T 28-03-2018 ALX04_RS11270 88c2a36c44776cd95300ee4e7937f33b 98 Pfam PF02302 PTS system, Lactose/Cellobiose specific IIB subunit 5 69 1.7E-12 T 28-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 ALX04_RS11270 88c2a36c44776cd95300ee4e7937f33b 98 SUPERFAMILY SSF52794 1 91 4.45E-19 T 28-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 ALX04_RS01585 22d38856897f9f53291a9a2691205218 309 Gene3D G3DSA:3.20.20.330 2 308 5.6E-106 T 28-03-2018 IPR003726 Homocysteine-binding domain Reactome: R-HSA-1614635 ALX04_RS01585 22d38856897f9f53291a9a2691205218 309 SUPERFAMILY SSF82282 3 302 3.14E-89 T 28-03-2018 IPR003726 Homocysteine-binding domain Reactome: R-HSA-1614635 ALX04_RS01585 22d38856897f9f53291a9a2691205218 309 Pfam PF02574 Homocysteine S-methyltransferase 14 300 1.9E-82 T 28-03-2018 IPR003726 Homocysteine-binding domain Reactome: R-HSA-1614635 ALX04_RS01585 22d38856897f9f53291a9a2691205218 309 PIRSF PIRSF037505 2 242 1.8E-14 T 28-03-2018 IPR017226 Betaine-homocysteine S-methyltransferase, BHMT GO:0005737|GO:0008270|GO:0009086|GO:0047150 Reactome: R-HSA-1614635 ALX04_RS01585 22d38856897f9f53291a9a2691205218 309 PIRSF PIRSF037505 259 307 1.3 T 28-03-2018 IPR017226 Betaine-homocysteine S-methyltransferase, BHMT GO:0005737|GO:0008270|GO:0009086|GO:0047150 Reactome: R-HSA-1614635 ALX04_RS04485 1e29c604e86ca535d2858c592d3815e9 425 TIGRFAM TIGR04092 LTA_DltD: D-alanyl-lipoteichoic acid biosynthesis protein DltD 11 393 3.6E-151 T 28-03-2018 IPR023896 D-alanyl-lipoteichoic acid biosynthesis DltD, Firmicutes ALX04_RS04485 1e29c604e86ca535d2858c592d3815e9 425 PIRSF PIRSF021438 3 396 1.8E-140 T 28-03-2018 IPR023896 D-alanyl-lipoteichoic acid biosynthesis DltD, Firmicutes ALX04_RS04485 1e29c604e86ca535d2858c592d3815e9 425 Gene3D G3DSA:3.40.50.1110 47 399 6.1E-4 T 28-03-2018 ALX04_RS04485 1e29c604e86ca535d2858c592d3815e9 425 Pfam PF04914 DltD protein 46 393 1.8E-131 T 28-03-2018 IPR006998 DltD ALX04_RS04210 dcfce8a979d2479364dfc924ce4990c3 213 Gene3D G3DSA:3.40.50.720 2 208 1.2E-24 T 28-03-2018 ALX04_RS04210 dcfce8a979d2479364dfc924ce4990c3 213 Pfam PF13460 NAD(P)H-binding 8 190 3.3E-47 T 28-03-2018 IPR016040 NAD(P)-binding domain ALX04_RS04210 dcfce8a979d2479364dfc924ce4990c3 213 SUPERFAMILY SSF51735 1 195 8.45E-28 T 28-03-2018 IPR016040 NAD(P)-binding domain ALX04_RS08055 424a23dc46a5dc9da55f8cf43854f625 551 Gene3D G3DSA:3.90.350.10 228 491 4.8E-8 T 28-03-2018 IPR014736 Transposase, Tn5-like, core ALX04_RS08055 424a23dc46a5dc9da55f8cf43854f625 551 Pfam PF01609 Transposase DDE domain 257 508 8.9E-33 T 28-03-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 ALX04_RS08055 424a23dc46a5dc9da55f8cf43854f625 551 Pfam PF05598 Transposase domain (DUF772) 45 101 2.2E-11 T 28-03-2018 IPR008490 Transposase InsH, N-terminal ALX04_RS01155 da96f1b262de067b6403e0c1d7fe57af 65 Pfam PF04221 RelB antitoxin 10 56 1.0E-7 T 28-03-2018 IPR007337 RelB antitoxin/Antitoxin DinJ ALX04_RS01155 da96f1b262de067b6403e0c1d7fe57af 65 TIGRFAM TIGR02384 RelB_DinJ: addiction module antitoxin, RelB/DinJ family 10 59 1.2E-12 T 28-03-2018 IPR007337 RelB antitoxin/Antitoxin DinJ ALX04_RS05560 6ab97c8741ca85d69af2f3e9e5ad4bcf 122 Pfam PF11877 Protein of unknown function (DUF3397) 8 117 2.3E-25 T 28-03-2018 IPR024515 Protein of unknown function DUF3397 ALX04_RS09355 82e2dce62fb3fa3a2beadf6733331b84 574 SUPERFAMILY SSF52540 324 565 3.48E-80 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase ALX04_RS09355 82e2dce62fb3fa3a2beadf6733331b84 574 SUPERFAMILY SSF90123 3 313 3.14E-55 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 ALX04_RS09355 82e2dce62fb3fa3a2beadf6733331b84 574 Pfam PF00664 ABC transporter transmembrane region 15 284 3.6E-32 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 ALX04_RS09355 82e2dce62fb3fa3a2beadf6733331b84 574 Pfam PF00005 ABC transporter 346 495 7.9E-31 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 ALX04_RS09355 82e2dce62fb3fa3a2beadf6733331b84 574 SMART SM00382 355 541 8.8E-17 T 28-03-2018 IPR003593 AAA+ ATPase domain ALX04_RS09355 82e2dce62fb3fa3a2beadf6733331b84 574 Gene3D G3DSA:3.40.50.300 316 571 2.5E-67 T 28-03-2018 ALX04_RS09355 82e2dce62fb3fa3a2beadf6733331b84 574 Gene3D G3DSA:1.20.1560.10 1 314 1.9E-53 T 28-03-2018 ALX04_RS04865 89dce79491d9e9a81488f3ebd92ad71d 160 TIGRFAM TIGR01558 sm_term_P27: putative phage terminase, small subunit, P27 family 38 153 3.0E-17 T 28-03-2018 IPR006448 Putative phage terminase, small subunit, P27 family ALX04_RS04865 89dce79491d9e9a81488f3ebd92ad71d 160 Pfam PF05119 Phage terminase, small subunit 46 133 4.1E-15 T 28-03-2018 IPR006448 Putative phage terminase, small subunit, P27 family ALX04_RS08690 e8821e24e313ad6994391c8a93db1e2e 73 SUPERFAMILY SSF89447 1 55 3.71E-7 T 28-03-2018 ALX04_RS08690 e8821e24e313ad6994391c8a93db1e2e 73 Gene3D G3DSA:2.10.260.10 3 41 2.5E-6 T 28-03-2018 ALX04_RS05495 4b67a307cf5d5efc9e5a26ec82f50ebe 261 Gene3D G3DSA:3.10.290.10 159 233 3.0E-6 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 ALX04_RS05495 4b67a307cf5d5efc9e5a26ec82f50ebe 261 SUPERFAMILY SSF55174 180 253 2.83E-25 T 28-03-2018 ALX04_RS05495 4b67a307cf5d5efc9e5a26ec82f50ebe 261 SUPERFAMILY SSF55174 38 128 2.83E-25 T 28-03-2018 ALX04_RS16005 34feb7d07c621e666b313defade14893 359 Pfam PF08867 FRG domain 34 123 1.1E-18 T 28-03-2018 IPR014966 FRG domain ALX04_RS16005 34feb7d07c621e666b313defade14893 359 SMART SM00901 31 133 9.1E-24 T 28-03-2018 IPR014966 FRG domain ALX04_RS00525 2dc82f1d8261da46958496fd92060040 189 PIRSF PIRSF027391 6 184 2.1E-73 T 28-03-2018 IPR014535 Predicted heptaprenyl diphosphate synthase, component I ALX04_RS00525 2dc82f1d8261da46958496fd92060040 189 Pfam PF07456 Heptaprenyl diphosphate synthase component I 20 166 5.5E-47 T 28-03-2018 IPR010898 Heptaprenyl diphosphate synthase component I ALX04_RS06695 aab277df2d17237e9ec8837bccc6c698 106 Gene3D G3DSA:3.40.390.10 2 102 1.1E-4 T 28-03-2018 IPR024079 Metallopeptidase, catalytic domain GO:0008237 ALX04_RS06630 65dfd60d05523e7b6f5264c08e5a9d10 207 Pfam PF06854 Bacteriophage Gp15 protein 4 180 3.2E-39 T 28-03-2018 IPR009660 Bacteriophage A500, Gp15 ALX04_RS02445 3fb252fabc5f88fd7031f3d221ed1daf 194 Gene3D G3DSA:3.10.450.40 52 112 4.7E-11 T 28-03-2018 ALX04_RS02445 3fb252fabc5f88fd7031f3d221ed1daf 194 Gene3D G3DSA:3.10.450.40 133 192 9.5E-14 T 28-03-2018 ALX04_RS02445 3fb252fabc5f88fd7031f3d221ed1daf 194 Pfam PF03413 Peptidase propeptide and YPEB domain 133 191 7.7E-8 T 28-03-2018 IPR025711 PepSY domain ALX04_RS02445 3fb252fabc5f88fd7031f3d221ed1daf 194 Pfam PF03413 Peptidase propeptide and YPEB domain 51 109 9.7E-7 T 28-03-2018 IPR025711 PepSY domain ALX04_RS08605 a819fd5c64136616fce1ad5811d0e069 192 Pfam PF06736 Protein of unknown function (DUF1211) 5 89 5.6E-22 T 28-03-2018 IPR010617 Endosomal/lysomomal potassium channel TMEM175 GO:0005267 ALX04_RS11010 bbbdf0d65ebbd2ced9385511aeef2d43 334 TIGRFAM TIGR01179 galE: UDP-glucose 4-epimerase GalE 2 326 4.4E-132 T 28-03-2018 IPR005886 UDP-glucose 4-epimerase GO:0003978|GO:0006012 KEGG: 00052+5.1.3.2|KEGG: 00520+5.1.3.2|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6397|MetaCyc: PWY-6527|MetaCyc: PWY-7328|MetaCyc: PWY-7344|Reactome: R-HSA-70370 ALX04_RS11010 bbbdf0d65ebbd2ced9385511aeef2d43 334 Gene3D G3DSA:3.90.25.10 165 331 7.9E-40 T 28-03-2018 ALX04_RS11010 bbbdf0d65ebbd2ced9385511aeef2d43 334 Gene3D G3DSA:3.40.50.720 2 164 1.4E-33 T 28-03-2018 ALX04_RS11010 bbbdf0d65ebbd2ced9385511aeef2d43 334 Pfam PF01370 NAD dependent epimerase/dehydratase family 3 252 3.2E-62 T 28-03-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 ALX04_RS11010 bbbdf0d65ebbd2ced9385511aeef2d43 334 SUPERFAMILY SSF51735 1 327 1.41E-97 T 28-03-2018 IPR016040 NAD(P)-binding domain ALX04_RS02215 73893a3a2dc30f0591abf0670fa1994e 401 PIRSF PIRSF037259 1 401 1.7E-133 T 28-03-2018 IPR010288 Bacterial ABC transporter EcsB GO:0016021 ALX04_RS02215 73893a3a2dc30f0591abf0670fa1994e 401 Pfam PF05975 Bacterial ABC transporter protein EcsB 2 384 1.7E-120 T 28-03-2018 IPR010288 Bacterial ABC transporter EcsB GO:0016021 ALX04_RS09640 8d09d1cee3ef443ca17743fac23e6f1f 208 Pfam PF07799 Protein of unknown function (DUF1643) 30 162 5.7E-9 T 28-03-2018 IPR012441 Protein of unknown function DUF1643 ALX04_RS11345 7127304bd4a3b0e3cebfbac77b50445a 182 TIGRFAM TIGR04518 ECF_S_folT_fam: ECF transporter S component, folate family 16 171 8.0E-25 T 28-03-2018 IPR030949 ECF transporter S component, folate family ALX04_RS03595 2884d22a4094063357f5ffde70f8f01e 245 Pfam PF06161 Protein of unknown function (DUF975) 158 243 5.0E-22 T 28-03-2018 IPR010380 Protein of unknown function DUF975 ALX04_RS03595 2884d22a4094063357f5ffde70f8f01e 245 Pfam PF06161 Protein of unknown function (DUF975) 1 162 8.9E-12 T 28-03-2018 IPR010380 Protein of unknown function DUF975 ALX04_RS10615 9b7b2a6313befcd10e124c780d70a1ca 127 SUPERFAMILY SSF160419 2 123 2.88E-33 T 28-03-2018 IPR009833 Uncharacterised protein DUF1398 ALX04_RS10615 9b7b2a6313befcd10e124c780d70a1ca 127 Gene3D G3DSA:3.30.1810.10 3 124 2.1E-22 T 28-03-2018 IPR009833 Uncharacterised protein DUF1398 ALX04_RS10615 9b7b2a6313befcd10e124c780d70a1ca 127 Pfam PF07166 Protein of unknown function (DUF1398) 15 121 1.4E-14 T 28-03-2018 IPR009833 Uncharacterised protein DUF1398 ALX04_RS11825 ad4f0e8b172b6a678b4739f6b73246bc 511 Pfam PF13556 PucR C-terminal helix-turn-helix domain 432 489 4.9E-21 T 28-03-2018 IPR025736 PucR C-terminal helix-turn-helix domain ALX04_RS11825 ad4f0e8b172b6a678b4739f6b73246bc 511 Gene3D G3DSA:3.30.450.40 78 247 1.1E-5 T 28-03-2018 IPR029016 GAF domain-like ALX04_RS11825 ad4f0e8b172b6a678b4739f6b73246bc 511 Gene3D G3DSA:1.10.10.60 415 469 1.3E-5 T 28-03-2018 ALX04_RS06520 88c73b6def3cdc0e4a727398cd793590 323 Gene3D G3DSA:1.20.120.330 107 297 5.0E-5 T 28-03-2018 ALX04_RS14785 40092540d8b2e956398f01665f0f2bfd 78 PRINTS PR01651 Protein-export SecG membrane protein signature 56 78 1.8E-11 T 28-03-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 ALX04_RS14785 40092540d8b2e956398f01665f0f2bfd 78 PRINTS PR01651 Protein-export SecG membrane protein signature 3 23 1.8E-11 T 28-03-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 ALX04_RS14785 40092540d8b2e956398f01665f0f2bfd 78 PRINTS PR01651 Protein-export SecG membrane protein signature 23 37 1.8E-11 T 28-03-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 ALX04_RS14785 40092540d8b2e956398f01665f0f2bfd 78 Pfam PF03840 Preprotein translocase SecG subunit 4 74 6.9E-21 T 28-03-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 ALX04_RS14785 40092540d8b2e956398f01665f0f2bfd 78 TIGRFAM TIGR00810 secG: preprotein translocase, SecG subunit 2 75 5.0E-23 T 28-03-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 ALX04_RS15610 12116ccac7a2f3d95c92541e92fc9093 92 Gene3D G3DSA:1.20.5.780 7 92 4.6E-6 T 28-03-2018 ALX04_RS15610 12116ccac7a2f3d95c92541e92fc9093 92 Pfam PF04221 RelB antitoxin 8 49 3.8E-5 T 28-03-2018 IPR007337 RelB antitoxin/Antitoxin DinJ ALX04_RS03520 ac62e5806eca48a859d792719346b9d3 174 Pfam PF00156 Phosphoribosyl transferase domain 2 145 3.8E-29 T 28-03-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 ALX04_RS03520 ac62e5806eca48a859d792719346b9d3 174 Gene3D G3DSA:3.40.50.2020 1 174 6.1E-37 T 28-03-2018 ALX04_RS03520 ac62e5806eca48a859d792719346b9d3 174 SUPERFAMILY SSF53271 3 168 1.23E-39 T 28-03-2018 IPR029057 Phosphoribosyltransferase-like ALX04_RS03520 ac62e5806eca48a859d792719346b9d3 174 Hamap MF_01219 Bifunctional protein PyrR [pyrR]. 2 174 35.181 T 28-03-2018 IPR023050 Bifunctional protein PyrR KEGG: 00240+2.4.2.9|MetaCyc: PWY-7183 ALX04_RS07465 b969b2d1389d8941c19ec078e46af979 667 Pfam PF00999 Sodium/hydrogen exchanger family 7 406 1.8E-53 T 28-03-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 ALX04_RS07465 b969b2d1389d8941c19ec078e46af979 667 TIGRFAM TIGR00831 a_cpa1: Na+/H+ antiporter 7 432 7.7E-85 T 28-03-2018 IPR004705 Cation/H+ exchanger, CPA1 family, bacteria GO:0006812|GO:0015299|GO:0016021 ALX04_RS01045 b18ac6cb537107d148fc8e3aebd11b51 392 Gene3D G3DSA:3.40.50.2000 214 381 6.3E-12 T 28-03-2018 ALX04_RS01045 b18ac6cb537107d148fc8e3aebd11b51 392 Pfam PF00534 Glycosyl transferases group 1 203 363 1.5E-9 T 28-03-2018 IPR001296 Glycosyl transferase, family 1 ALX04_RS01045 b18ac6cb537107d148fc8e3aebd11b51 392 Pfam PF09314 Domain of unknown function (DUF1972) 6 189 3.9E-81 T 28-03-2018 IPR015393 Domain of unknown function DUF1972 ALX04_RS01045 b18ac6cb537107d148fc8e3aebd11b51 392 SUPERFAMILY SSF53756 14 389 1.94E-28 T 28-03-2018 ALX04_RS01205 f9d85ba52b45b70778c3d3e98be37d5f 359 Pfam PF01757 Acyltransferase family 6 322 8.3E-24 T 28-03-2018 IPR002656 Acyltransferase 3 GO:0016747 ALX04_RS15320 6436f5b2baa9a228045c83a0ee119947 615 SUPERFAMILY SSF52266 430 604 5.31E-12 T 28-03-2018 IPR013830 SGNH hydrolase-type esterase domain ALX04_RS15320 6436f5b2baa9a228045c83a0ee119947 615 Pfam PF01757 Acyltransferase family 16 349 9.6E-23 T 28-03-2018 IPR002656 Acyltransferase 3 GO:0016747 ALX04_RS15320 6436f5b2baa9a228045c83a0ee119947 615 Gene3D G3DSA:3.40.50.1110 416 607 2.3E-10 T 28-03-2018 ALX04_RS12220 fd04d51caf4998fffa27a5de981441c9 109 Gene3D G3DSA:1.10.10.10 4 107 1.3E-6 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS12220 fd04d51caf4998fffa27a5de981441c9 109 Pfam PF03551 Transcriptional regulator PadR-like family 27 91 2.2E-5 T 28-03-2018 IPR005149 Transcription regulator PadR, N-terminal ALX04_RS12220 fd04d51caf4998fffa27a5de981441c9 109 SUPERFAMILY SSF46785 20 99 6.26E-6 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS10930 7dd585dacf934184d063966084b41155 397 Gene3D G3DSA:3.40.50.300 4 183 1.1E-11 T 28-03-2018 ALX04_RS10930 7dd585dacf934184d063966084b41155 397 SUPERFAMILY SSF52540 9 59 2.01E-10 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase ALX04_RS10930 7dd585dacf934184d063966084b41155 397 SUPERFAMILY SSF52540 86 208 2.01E-10 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase ALX04_RS15970 b41876de9b58f48f9baa80624dc416ba 81 Pfam PF01548 Transposase 6 81 2.0E-11 T 28-03-2018 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 ALX04_RS04825 5fd454fc908edbf8c88380ed98666073 128 TIGRFAM TIGR01725 phge_HK97_gp10: phage protein, HK97 gp10 family 20 113 4.5E-8 T 28-03-2018 IPR010064 Bacteriophage HK97-gp10, putative tail-component ALX04_RS04825 5fd454fc908edbf8c88380ed98666073 128 Pfam PF04883 Bacteriophage HK97-gp10, putative tail-component 23 92 3.6E-7 T 28-03-2018 IPR010064 Bacteriophage HK97-gp10, putative tail-component ALX04_RS08105 d09d348d63c6faee62c5e60a12ab4123 363 Pfam PF05913 Bacterial protein of unknown function (DUF871) 3 359 2.0E-137 T 28-03-2018 IPR008589 Protein of unknown function DUF871, prokaryotic ALX04_RS08105 d09d348d63c6faee62c5e60a12ab4123 363 Gene3D G3DSA:3.20.20.70 3 238 3.5E-94 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 ALX04_RS08105 d09d348d63c6faee62c5e60a12ab4123 363 SUPERFAMILY SSF51445 1 240 6.06E-94 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily ALX04_RS08105 d09d348d63c6faee62c5e60a12ab4123 363 Gene3D G3DSA:2.40.100.10 247 360 1.5E-37 T 28-03-2018 IPR029000 Cyclophilin-like domain ALX04_RS08105 d09d348d63c6faee62c5e60a12ab4123 363 SUPERFAMILY SSF50891 245 360 7.96E-37 T 28-03-2018 IPR029000 Cyclophilin-like domain ALX04_RS01870 023107d89454503f9ef9fb9330c2db27 545 Gene3D G3DSA:3.40.50.300 15 249 1.1E-17 T 28-03-2018 ALX04_RS01870 023107d89454503f9ef9fb9330c2db27 545 SUPERFAMILY SSF52540 13 292 1.56E-19 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase ALX04_RS07645 e5c2b333b1741dd39f22cda351fc9393 391 SUPERFAMILY SSF53756 18 370 3.77E-51 T 28-03-2018 ALX04_RS07645 e5c2b333b1741dd39f22cda351fc9393 391 Gene3D G3DSA:3.40.50.2000 183 356 4.0E-35 T 28-03-2018 ALX04_RS07645 e5c2b333b1741dd39f22cda351fc9393 391 Pfam PF00534 Glycosyl transferases group 1 194 351 1.9E-24 T 28-03-2018 IPR001296 Glycosyl transferase, family 1 ALX04_RS07245 5000e9e98f656e59b7902d82e39140d0 260 Pfam PF00005 ABC transporter 29 185 3.0E-25 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 ALX04_RS07245 5000e9e98f656e59b7902d82e39140d0 260 Gene3D G3DSA:3.40.50.300 5 254 1.5E-49 T 28-03-2018 ALX04_RS07245 5000e9e98f656e59b7902d82e39140d0 260 SMART SM00382 38 233 1.6E-9 T 28-03-2018 IPR003593 AAA+ ATPase domain ALX04_RS07245 5000e9e98f656e59b7902d82e39140d0 260 ProSitePatterns PS00211 ABC transporters family signature. 157 171 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 ALX04_RS07245 5000e9e98f656e59b7902d82e39140d0 260 SUPERFAMILY SSF52540 7 240 4.46E-50 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase ALX04_RS13510 82a018e0565026ed425df048fd01319d 280 Pfam PF01904 Protein of unknown function DUF72 21 263 3.2E-57 T 28-03-2018 IPR002763 Protein of unknown function DUF72 ALX04_RS13510 82a018e0565026ed425df048fd01319d 280 SUPERFAMILY SSF117396 1 266 1.44E-75 T 28-03-2018 IPR002763 Protein of unknown function DUF72 ALX04_RS13510 82a018e0565026ed425df048fd01319d 280 Gene3D G3DSA:3.20.20.410 1 280 7.4E-73 T 28-03-2018 IPR002763 Protein of unknown function DUF72 ALX04_RS08585 9c5ebee7bc494eebfc774d2edf8e19c6 198 SUPERFAMILY SSF51735 1 187 1.04E-31 T 28-03-2018 IPR016040 NAD(P)-binding domain ALX04_RS08585 9c5ebee7bc494eebfc774d2edf8e19c6 198 Pfam PF13460 NAD(P)H-binding 8 183 7.8E-43 T 28-03-2018 IPR016040 NAD(P)-binding domain ALX04_RS08585 9c5ebee7bc494eebfc774d2edf8e19c6 198 Gene3D G3DSA:3.40.50.720 1 197 1.0E-20 T 28-03-2018 ALX04_RS07500 a20e9613d60c636dcc4d76c3a59c1cec 93 Pfam PF08951 Enterocin A Immunity 9 62 7.6E-7 T 28-03-2018 IPR015046 Enterocin A Immunity ALX04_RS07500 a20e9613d60c636dcc4d76c3a59c1cec 93 Gene3D G3DSA:1.20.1440.50 9 77 9.4E-16 T 28-03-2018 IPR023130 Ta0600-like domain ALX04_RS07500 a20e9613d60c636dcc4d76c3a59c1cec 93 SUPERFAMILY SSF109797 3 91 9.94E-22 T 28-03-2018 ALX04_RS00105 2cbbc05fcbc74c5ec5ffcb9568ce0f84 416 Pfam PF07907 YibE/F-like protein 175 407 1.3E-63 T 28-03-2018 IPR012507 YibE/F-like ALX04_RS00795 70877508d11155424339dec8df2ecd92 479 Pfam PF01654 Cytochrome bd terminal oxidase subunit I 10 456 3.9E-159 T 28-03-2018 IPR002585 Cytochrome ubiquinol oxidase subunit 1 GO:0009055|GO:0019646|GO:0070069 ALX04_RS00795 70877508d11155424339dec8df2ecd92 479 PIRSF PIRSF006446 3 477 8.3E-153 T 28-03-2018 IPR002585 Cytochrome ubiquinol oxidase subunit 1 GO:0009055|GO:0019646|GO:0070069 ALX04_RS13635 cc5565618496007a1fbfd3f59f3483b3 426 Pfam PF03222 Tryptophan/tyrosine permease family 19 411 1.0E-15 T 28-03-2018 IPR018227 Amino acid/polyamine transporter 2 GO:0003333 ALX04_RS01685 d33eaf059ac87e101726b96fb842ff47 321 Gene3D G3DSA:1.20.58.370 24 72 4.5E-8 T 28-03-2018 IPR035277 Maltose transport system permease protein MalF N-terminal domain ALX04_RS01685 d33eaf059ac87e101726b96fb842ff47 321 Gene3D G3DSA:1.10.3720.10 89 320 1.7E-38 T 28-03-2018 ALX04_RS01685 d33eaf059ac87e101726b96fb842ff47 321 SUPERFAMILY SSF161098 83 310 2.88E-52 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 ALX04_RS01685 d33eaf059ac87e101726b96fb842ff47 321 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 115 319 2.3E-16 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 ALX04_RS01685 d33eaf059ac87e101726b96fb842ff47 321 SUPERFAMILY SSF160964 34 68 4.32E-6 T 28-03-2018 ALX04_RS00830 752a050bfeeea73cd689f0ae84072ba1 304 PIRSF PIRSF005355 2 304 1.5E-38 T 28-03-2018 IPR026046 UbiA prenyltransferase domain containing protein 1 GO:0004659 Reactome: R-HSA-6806664 ALX04_RS00830 752a050bfeeea73cd689f0ae84072ba1 304 Pfam PF01040 UbiA prenyltransferase family 19 271 1.3E-17 T 28-03-2018 IPR000537 UbiA prenyltransferase family GO:0016021|GO:0016765 ALX04_RS04030 3b6a7a09c9e950887063351871fb2bc8 401 Pfam PF04932 O-Antigen ligase 199 323 4.0E-7 T 28-03-2018 IPR007016 O-antigen ligase-related ALX04_RS08985 025af7712c6742159ac936dbcf51d170 364 Pfam PF13303 Phosphotransferase system, EIIC 21 360 3.7E-87 T 28-03-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 ALX04_RS00630 f9885ce4621c987952a36c330c94a196 310 Pfam PF05681 Fumarate hydratase (Fumerase) 24 289 4.5E-73 T 28-03-2018 IPR004646 Fe-S hydro-lyase, tartrate dehydratase alpha-type, catalytic domain GO:0016829 ALX04_RS00630 f9885ce4621c987952a36c330c94a196 310 TIGRFAM TIGR00722 ttdA_fumA_fumB: hydrolyase, tartrate alpha subunit/fumarate domain protein, Fe-S type 20 291 5.5E-90 T 28-03-2018 IPR004646 Fe-S hydro-lyase, tartrate dehydratase alpha-type, catalytic domain GO:0016829 ALX04_RS07850 f78537ac9c8f96e8c5231233ee86a907 446 TIGRFAM TIGR00801 ncs2: uracil-xanthine permease 11 423 6.5E-131 T 28-03-2018 IPR006042 Xanthine/uracil permease GO:0005215|GO:0016020|GO:0055085 Reactome: R-HSA-196836 ALX04_RS07850 f78537ac9c8f96e8c5231233ee86a907 446 Pfam PF00860 Permease family 14 392 2.1E-109 T 28-03-2018 IPR006043 Xanthine/uracil/vitamin C permease GO:0005215|GO:0006810|GO:0016020|GO:0055085 ALX04_RS07850 f78537ac9c8f96e8c5231233ee86a907 446 TIGRFAM TIGR03173 pbuX: xanthine permease 18 425 1.8E-156 T 28-03-2018 IPR017588 Uric acid permease UacT-like GO:0006810|GO:0016021 ALX04_RS07850 f78537ac9c8f96e8c5231233ee86a907 446 ProSitePatterns PS01116 Xanthine/uracil permeases family signature. 340 360 - T 28-03-2018 IPR006042 Xanthine/uracil permease GO:0005215|GO:0016020|GO:0055085 Reactome: R-HSA-196836 ALX04_RS02260 888e070d707b0e13b82a613e9f538f7e 74 SUPERFAMILY SSF50037 12 66 1.95E-10 T 28-03-2018 IPR008988 Transcriptional repressor, C-terminal ALX04_RS02260 888e070d707b0e13b82a613e9f538f7e 74 Pfam PF04023 FeoA domain 11 66 1.9E-9 T 28-03-2018 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 ALX04_RS02260 888e070d707b0e13b82a613e9f538f7e 74 SMART SM00899 1 74 0.0014 T 28-03-2018 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 ALX04_RS02260 888e070d707b0e13b82a613e9f538f7e 74 Gene3D G3DSA:2.30.30.90 5 71 2.7E-10 T 28-03-2018 ALX04_RS01390 f7b7eccf8c01382d39c2b1bcf9c4bb67 129 Pfam PF01047 MarR family 31 87 3.5E-9 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 ALX04_RS01390 f7b7eccf8c01382d39c2b1bcf9c4bb67 129 SMART SM00347 24 129 2.2E-9 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 ALX04_RS01390 f7b7eccf8c01382d39c2b1bcf9c4bb67 129 Gene3D G3DSA:1.10.10.10 5 122 8.7E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS01390 f7b7eccf8c01382d39c2b1bcf9c4bb67 129 SUPERFAMILY SSF46785 6 114 7.49E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS06655 5b58102befdf88a03f2a47b8c187a364 117 Pfam PF10665 Minor capsid protein 7 116 9.7E-17 T 28-03-2018 IPR019612 Minor capsid protein, putative ALX04_RS11730 fcef39ee826bad5a73833ee906b027b5 284 Pfam PF09648 YycH protein 32 255 1.3E-53 T 28-03-2018 IPR018604 Regulatory protein YycH-like GO:0016021 ALX04_RS07880 a033896142d5924e9011a0d3b8f3d03e 222 Gene3D G3DSA:3.20.20.210 34 222 2.2E-16 T 28-03-2018 ALX04_RS07880 a033896142d5924e9011a0d3b8f3d03e 222 SUPERFAMILY SSF51726 35 214 1.44E-13 T 28-03-2018 ALX04_RS00925 4a054de3f7bcc0252e6d759876fc3b96 258 SUPERFAMILY SSF51445 54 252 4.49E-30 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily ALX04_RS00925 4a054de3f7bcc0252e6d759876fc3b96 258 Gene3D G3DSA:3.20.20.80 42 256 2.2E-28 T 28-03-2018 ALX04_RS00925 4a054de3f7bcc0252e6d759876fc3b96 258 SMART SM00641 56 162 2.3E-4 T 28-03-2018 IPR018077 Glycoside hydrolase, family 25 subgroup ALX04_RS00925 4a054de3f7bcc0252e6d759876fc3b96 258 Pfam PF01183 Glycosyl hydrolases family 25 61 215 2.5E-15 T 28-03-2018 IPR002053 Glycoside hydrolase, family 25 GO:0003796|GO:0009253|GO:0016998 ALX04_RS10340 8a0627340e239bb0fcc9815c7d2c0fe9 177 Pfam PF02674 Colicin V production protein 3 156 2.7E-27 T 28-03-2018 IPR003825 Colicin V production, CvpA GO:0009403|GO:0016020 ALX04_RS08100 ea727934738aadaaa59c87a9113566e7 73 Pfam PF11195 Protein of unknown function (DUF2829) 2 72 4.7E-26 T 28-03-2018 IPR021361 Protein of unknown function DUF2829 ALX04_RS04760 be2207bb85d37243c609fb0f6a519149 176 Pfam PF04531 Bacteriophage holin 14 71 2.0E-4 T 28-03-2018 IPR006485 Bacteriophage holin ALX04_RS11725 d8cbfed04a729ebedf81ddbe29978dc0 441 Pfam PF07435 YycH protein 13 433 6.5E-45 T 28-03-2018 IPR009996 Regulatory protein YycH ALX04_RS06490 504be70cbe8b6cd3c958c0e959be12ea 240 Pfam PF07685 CobB/CobQ-like glutamine amidotransferase domain 8 201 1.2E-43 T 28-03-2018 IPR011698 CobB/CobQ-like glutamine amidotransferase GO:0003824|GO:0009236 ALX04_RS06490 504be70cbe8b6cd3c958c0e959be12ea 240 Gene3D G3DSA:3.40.50.880 14 219 5.7E-18 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like ALX04_RS06490 504be70cbe8b6cd3c958c0e959be12ea 240 SUPERFAMILY SSF52317 21 194 3.2E-26 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like ALX04_RS11435 828550423505ee121c44851a54462ba2 168 Pfam PF06923 Glucitol operon activator protein (GutM) 5 111 3.5E-32 T 28-03-2018 IPR009693 Glucitol operon activator ALX04_RS11435 828550423505ee121c44851a54462ba2 168 PIRSF PIRSF011474 1 160 2.0E-63 T 28-03-2018 IPR009693 Glucitol operon activator ALX04_RS05890 157c6a2e160e3b7034024e17a47be8f2 349 Pfam PF00482 Type II secretion system (T2SS), protein F 34 150 4.8E-10 T 28-03-2018 IPR018076 Type II secretion system F domain ALX04_RS05890 157c6a2e160e3b7034024e17a47be8f2 349 PRINTS PR00812 Bacterial general secretion pathway protein F signature 312 326 7.6E-6 T 28-03-2018 IPR003004 GspF/PilC family ALX04_RS05890 157c6a2e160e3b7034024e17a47be8f2 349 PRINTS PR00812 Bacterial general secretion pathway protein F signature 122 150 7.6E-6 T 28-03-2018 IPR003004 GspF/PilC family ALX04_RS05890 157c6a2e160e3b7034024e17a47be8f2 349 PRINTS PR00812 Bacterial general secretion pathway protein F signature 328 347 7.6E-6 T 28-03-2018 IPR003004 GspF/PilC family ALX04_RS09820 b37185e8791cc37683e91011dc7ed0df 144 Gene3D G3DSA:1.10.260.40 13 130 4.1E-5 T 28-03-2018 ALX04_RS08715 d58bffe6811686dc8571d303c293cf6f 197 Gene3D G3DSA:3.40.50.720 1 190 5.9E-22 T 28-03-2018 ALX04_RS08715 d58bffe6811686dc8571d303c293cf6f 197 SUPERFAMILY SSF51735 1 179 6.47E-27 T 28-03-2018 IPR016040 NAD(P)-binding domain ALX04_RS08715 d58bffe6811686dc8571d303c293cf6f 197 Pfam PF03807 NADP oxidoreductase coenzyme F420-dependent 3 91 4.3E-14 T 28-03-2018 IPR028939 Pyrroline-5-carboxylate reductase, catalytic, N-terminal ALX04_RS08850 9ff8791cc5d361be5b54d76ab3e1a85d 431 SUPERFAMILY SSF53649 4 413 2.62E-93 T 28-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 ALX04_RS08850 9ff8791cc5d361be5b54d76ab3e1a85d 431 Gene3D G3DSA:3.40.720.10 5 431 9.5E-47 T 28-03-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 ALX04_RS08850 9ff8791cc5d361be5b54d76ab3e1a85d 431 Pfam PF01663 Type I phosphodiesterase / nucleotide pyrophosphatase 7 373 3.7E-54 T 28-03-2018 IPR002591 Type I phosphodiesterase/nucleotide pyrophosphatase/phosphate transferase GO:0003824 ALX04_RS10680 65d02031090e81d85f242c1f62746919 153 Pfam PF12821 Threonine/Serine exporter, ThrE 12 145 1.1E-40 T 28-03-2018 IPR024528 Threonine/Serine exporter, ThrE ALX04_RS10705 52280d3ebdd32d0f3440f95786bb8d06 107 ProDom PD070949 MEMBRANE PROTEIN YVLA SPANNING SIMILAR SE2241 LMO0604 LMO2177 LIN2280 INTEGRAL 1 104 3.0E-32 T 28-03-2018 ALX04_RS06770 fd120bec1d4d897654ba064d6cc44763 299 Pfam PF03837 RecT family 32 233 1.1E-43 T 28-03-2018 IPR018330 RecT family GO:0003677|GO:0006259 ALX04_RS06770 fd120bec1d4d897654ba064d6cc44763 299 TIGRFAM TIGR00616 rect: recombinase, phage RecT family 45 204 1.4E-20 T 28-03-2018 IPR004590 DNA single-strand annealing protein RecT GO:0003677|GO:0006259 ALX04_RS01340 072c0c793bc086710cec377d93e5ee84 484 Gene3D G3DSA:2.140.10.30 49 452 3.1E-8 T 28-03-2018 ALX04_RS01340 072c0c793bc086710cec377d93e5ee84 484 SUPERFAMILY SSF75011 215 386 1.24E-6 T 28-03-2018 ALX04_RS01260 935bc3f9c0e09b1cca902a9f32508779 252 Pfam PF06338 ComK protein 115 199 2.4E-5 T 28-03-2018 IPR010461 Competence protein ComK GO:0030420 ALX04_RS00420 b7853e618bfff2fdb08e9abd847863f4 64 Gene3D G3DSA:1.10.287.310 1 64 7.6E-22 T 28-03-2018 ALX04_RS00420 b7853e618bfff2fdb08e9abd847863f4 64 Pfam PF00831 Ribosomal L29 protein 4 59 2.9E-23 T 28-03-2018 IPR001854 Ribosomal protein L29/L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 ALX04_RS00420 b7853e618bfff2fdb08e9abd847863f4 64 Hamap MF_00374 50S ribosomal protein L29 [rpmC]. 1 60 18.055 T 28-03-2018 IPR001854 Ribosomal protein L29/L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 ALX04_RS00420 b7853e618bfff2fdb08e9abd847863f4 64 ProSitePatterns PS00579 Ribosomal protein L29 signature. 39 53 - T 28-03-2018 IPR018254 Ribosomal protein L29, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 ALX04_RS00420 b7853e618bfff2fdb08e9abd847863f4 64 TIGRFAM TIGR00012 L29: ribosomal protein uL29 5 60 1.9E-21 T 28-03-2018 IPR001854 Ribosomal protein L29/L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 ALX04_RS00420 b7853e618bfff2fdb08e9abd847863f4 64 SUPERFAMILY SSF46561 1 63 6.02E-22 T 28-03-2018 IPR001854 Ribosomal protein L29/L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 ALX04_RS07805 84096911da20aeb97b94297ebed1466f 212 SUPERFAMILY SSF53271 12 209 9.83E-52 T 28-03-2018 IPR029057 Phosphoribosyltransferase-like ALX04_RS07805 84096911da20aeb97b94297ebed1466f 212 Gene3D G3DSA:3.40.50.2020 4 211 1.6E-37 T 28-03-2018 ALX04_RS07805 84096911da20aeb97b94297ebed1466f 212 Pfam PF00156 Phosphoribosyl transferase domain 47 145 1.2E-13 T 28-03-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 ALX04_RS07805 84096911da20aeb97b94297ebed1466f 212 Hamap MF_01208 Orotate phosphoribosyltransferase [pyrE]. 1 212 30.253 T 28-03-2018 IPR023031 Orotate phosphoribosyltransferase GO:0004588|GO:0006221 KEGG: 00240+2.4.2.10|KEGG: 00983+2.4.2.10|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 ALX04_RS07805 84096911da20aeb97b94297ebed1466f 212 TIGRFAM TIGR00336 pyrE: orotate phosphoribosyltransferase 18 177 2.5E-44 T 28-03-2018 IPR004467 Orotate phosphoribosyl transferase domain GO:0004588 KEGG: 00240+2.4.2.10|KEGG: 00983+2.4.2.10|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 ALX04_RS03660 71f5015a6626319ef03b55e90cb76b3b 530 Pfam PF02652 L-lactate permease 4 521 1.5E-88 T 28-03-2018 IPR003804 L-lactate permease GO:0005887|GO:0015129|GO:0015727 ALX04_RS12015 d7d6de57b616b9bab7bbe121471b1e4d 163 Gene3D G3DSA:3.10.20.300 99 163 2.4E-17 T 28-03-2018 ALX04_RS12015 d7d6de57b616b9bab7bbe121471b1e4d 163 Pfam PF01969 Protein of unknown function DUF111 13 149 5.4E-46 T 28-03-2018 IPR035108 LarC/UPF0272 ALX04_RS12015 d7d6de57b616b9bab7bbe121471b1e4d 163 Gene3D G3DSA:3.30.70.1380 15 97 9.7E-31 T 28-03-2018 ALX04_RS12580 d85cfd68bc44e4ae922d3d2a2d6b450f 183 Gene3D G3DSA:1.10.1660.10 12 177 5.6E-11 T 28-03-2018 ALX04_RS00240 77d55d9c4477cf4122e061140609207d 153 Pfam PF12821 Threonine/Serine exporter, ThrE 7 134 3.9E-39 T 28-03-2018 IPR024528 Threonine/Serine exporter, ThrE ALX04_RS06940 f27edc9a6fe4f1abbe2335a1d1763ab3 464 Pfam PF05272 Virulence-associated protein E 132 327 9.3E-62 T 28-03-2018 IPR007936 Virulence-associated E ALX04_RS15305 14a16d2a96b7c00e689e7b28b72585ad 230 Pfam PF02517 CAAX protease self-immunity 125 218 3.0E-14 T 28-03-2018 IPR003675 CAAX amino terminal protease GO:0016020 Reactome: R-HSA-5689880 ALX04_RS05825 34b6f49b431ec8c6b480d47ef82ae5ab 213 TIGRFAM TIGR01906 integ_TIGR01906: integral membrane protein TIGR01906 17 210 1.1E-35 T 28-03-2018 IPR010178 Integral membrane protein 1906 ALX04_RS05825 34b6f49b431ec8c6b480d47ef82ae5ab 213 Pfam PF07314 Protein of unknown function (DUF1461) 13 183 3.0E-42 T 28-03-2018 IPR010178 Integral membrane protein 1906 ALX04_RS13215 9ab964bc1854269e6feb8862a8fffa3a 459 Pfam PF14449 Pre-toxin TG 267 326 2.1E-11 T 28-03-2018 IPR027797 Pre-toxin TG domain ALX04_RS04155 bfac85f28e3a9c57764725f86f4df612 174 Pfam PF06028 Alpha/beta hydrolase of unknown function (DUF915) 2 173 3.5E-40 T 28-03-2018 IPR010315 Protein of unknown function DUF915, hydrolase-like ALX04_RS04155 bfac85f28e3a9c57764725f86f4df612 174 Gene3D G3DSA:3.40.50.1820 2 174 6.5E-18 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold ALX04_RS04155 bfac85f28e3a9c57764725f86f4df612 174 SUPERFAMILY SSF53474 15 130 2.58E-11 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold ALX04_RS15005 cff3c83a91958aa7b2d2aacb26f05683 269 Pfam PF04991 LicD family 21 242 9.4E-60 T 28-03-2018 IPR007074 LicD family ALX04_RS14435 854ad9ff9dfb98783c2c50e02994e94a 262 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 90 261 2.0E-12 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 ALX04_RS14435 854ad9ff9dfb98783c2c50e02994e94a 262 SUPERFAMILY SSF161098 67 255 1.1E-29 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 ALX04_RS14435 854ad9ff9dfb98783c2c50e02994e94a 262 Gene3D G3DSA:1.10.3720.10 12 262 8.9E-26 T 28-03-2018 ALX04_RS14435 854ad9ff9dfb98783c2c50e02994e94a 262 TIGRFAM TIGR01097 PhnE: phosphonate ABC transporter, permease protein PhnE 9 261 1.7E-72 T 28-03-2018 IPR005769 ABC transporter, permease PhnE/PtxC GO:0005887|GO:0015604|GO:0015716 ALX04_RS02200 98decbe12efbac25014c6d418aaa574a 113 Gene3D G3DSA:1.20.1170.10 15 113 5.0E-5 T 28-03-2018 ALX04_RS04765 4a1902400b1e390422c7e6617b1f39d8 87 Gene3D G3DSA:1.20.5.110 2 86 3.6E-5 T 28-03-2018 ALX04_RS04765 4a1902400b1e390422c7e6617b1f39d8 87 Pfam PF10779 Haemolysin XhlA 13 82 2.5E-15 T 28-03-2018 IPR019715 Haemolysin XhlA ALX04_RS00060 6c9d8110dcad4a17ff2a4a8e9b5a3445 468 Gene3D G3DSA:3.60.60.10 9 298 7.0E-55 T 28-03-2018 ALX04_RS00060 6c9d8110dcad4a17ff2a4a8e9b5a3445 468 Pfam PF03577 Peptidase family C69 8 402 3.6E-178 T 28-03-2018 IPR005322 Peptidase C69, dipeptidase A GO:0006508|GO:0016805 ALX04_RS13415 fe42ae4ad77c26a15121f9919f9e1ccc 226 Pfam PF02517 CAAX protease self-immunity 125 220 2.5E-9 T 28-03-2018 IPR003675 CAAX amino terminal protease GO:0016020 Reactome: R-HSA-5689880 ALX04_RS05425 976669049bb9c832e354c70a9bd8dd81 452 Pfam PF02386 Cation transport protein 24 431 8.7E-55 T 28-03-2018 IPR003445 Cation transporter GO:0006812|GO:0008324|GO:0055085 ALX04_RS04300 8d9f168883cc73a53a8ab5e778382193 250 Pfam PF12679 ABC-2 family transporter protein 55 248 4.0E-13 T 28-03-2018 IPR032688 ABC-2 family transporter protein GO:0006810 ALX04_RS11520 9cd49a10146e4c515d18f48d615c5299 512 Gene3D G3DSA:2.60.40.10 233 375 0.0049 T 28-03-2018 IPR013783 Immunoglobulin-like fold ALX04_RS06995 33356e0e9edffbdf9e77469fd6129946 658 Gene3D G3DSA:1.10.287.620 225 518 2.4E-7 T 28-03-2018 ALX04_RS06995 33356e0e9edffbdf9e77469fd6129946 658 Gene3D G3DSA:1.20.5.340 80 215 1.7E-4 T 28-03-2018 ALX04_RS09115 ad379d73db39a04cca6bbfdb7887be22 397 Gene3D G3DSA:3.40.50.2300 198 381 3.8E-30 T 28-03-2018 ALX04_RS09115 ad379d73db39a04cca6bbfdb7887be22 397 Gene3D G3DSA:3.40.50.2300 27 197 3.6E-33 T 28-03-2018 ALX04_RS09115 ad379d73db39a04cca6bbfdb7887be22 397 Pfam PF13458 Periplasmic binding protein 40 386 7.4E-59 T 28-03-2018 IPR028081 Leucine-binding protein domain ALX04_RS09115 ad379d73db39a04cca6bbfdb7887be22 397 SUPERFAMILY SSF53822 40 393 2.83E-84 T 28-03-2018 IPR028082 Periplasmic binding protein-like I ALX04_RS14180 10431450aa6f56c82d088a168186d15a 397 Pfam PF03816 Cell envelope-related transcriptional attenuator domain 111 252 9.3E-43 T 28-03-2018 IPR004474 Cell envelope-related transcriptional attenuator domain ALX04_RS14180 10431450aa6f56c82d088a168186d15a 397 TIGRFAM TIGR00350 lytR_cpsA_psr: cell envelope-related function transcriptional attenuator common domain 110 252 5.3E-41 T 28-03-2018 IPR004474 Cell envelope-related transcriptional attenuator domain ALX04_RS00355 6679314eeb6542861a30e789b717a2ba 226 Pfam PF06750 Bacterial Peptidase A24 N-terminal domain 8 87 6.0E-24 T 28-03-2018 IPR010627 Peptidase A24A, N-terminal ALX04_RS12775 5eb4545e143d3e0f7379a3005cd62aeb 215 Gene3D G3DSA:3.40.50.980 1 202 7.6E-5 T 28-03-2018 ALX04_RS11780 82a57b9c3050e8e1c16b3508d230a64e 215 Pfam PF07299 Elongation factor G-binding protein, N-terminal 4 87 7.2E-23 T 28-03-2018 IPR010841 Elongation factor G-binding protein, N-terminal ALX04_RS11780 82a57b9c3050e8e1c16b3508d230a64e 215 Pfam PF16571 FBP C-terminal treble-clef zinc-finger 100 200 1.0E-8 T 28-03-2018 IPR032330 Elongation factor G-binding protein, C-terminal treble-clef zinc-finger ALX04_RS02430 fc3a089edeaadf979055adf9ef82db79 383 SUPERFAMILY SSF52374 10 105 1.97E-19 T 28-03-2018 ALX04_RS02430 fc3a089edeaadf979055adf9ef82db79 383 SUPERFAMILY SSF52374 156 230 1.97E-19 T 28-03-2018 ALX04_RS02430 fc3a089edeaadf979055adf9ef82db79 383 Gene3D G3DSA:3.40.50.620 1 229 9.9E-47 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold ALX04_RS02430 fc3a089edeaadf979055adf9ef82db79 383 Hamap MF_01539 UPF0348 protein . 2 377 37.115 T 28-03-2018 IPR008513 Uncharacterised protein family UPF0348 ALX04_RS02430 fc3a089edeaadf979055adf9ef82db79 383 Pfam PF05636 HIGH Nucleotidyl Transferase 1 368 1.7E-118 T 28-03-2018 IPR008513 Uncharacterised protein family UPF0348 ALX04_RS04170 ee2232ccd9790bee67cb71e20fdf203f 97 Pfam PF06028 Alpha/beta hydrolase of unknown function (DUF915) 38 95 4.1E-9 T 28-03-2018 IPR010315 Protein of unknown function DUF915, hydrolase-like ALX04_RS15355 826cafdf2d25f269a6e9a34c70b7c5a2 309 Pfam PF15983 Domain of unknown function (DUF4767) 61 195 8.2E-43 T 28-03-2018 IPR031927 Domain of unknown function DUF4767 ALX04_RS03690 8647524b5886f54ef9f27d9b7ea00c43 175 SUPERFAMILY SSF55729 1 164 5.4E-29 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase ALX04_RS03690 8647524b5886f54ef9f27d9b7ea00c43 175 Gene3D G3DSA:3.40.630.30 1 175 6.3E-30 T 28-03-2018 ALX04_RS03690 8647524b5886f54ef9f27d9b7ea00c43 175 Pfam PF00583 Acetyltransferase (GNAT) family 55 148 2.5E-14 T 28-03-2018 IPR000182 GNAT domain GO:0008080 ALX04_RS04895 c36704b2e073a7c5621d11a7334106b1 142 Pfam PF07852 Protein of unknown function (DUF1642) 80 141 1.8E-6 T 28-03-2018 IPR012865 Protein of unknown function DUF1642 ALX04_RS08245 c0031a8d3b67bb921b2885dfbf5b2dbc 478 PIRSF PIRSF006060 1 477 1.3E-47 T 28-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 ALX04_RS08245 c0031a8d3b67bb921b2885dfbf5b2dbc 478 Pfam PF13520 Amino acid permease 9 449 4.8E-30 T 28-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 ALX04_RS10635 824c65f4a002cef7687068d2b81fb027 156 Pfam PF08876 Domain of unknown function (DUF1836) 14 107 1.5E-20 T 28-03-2018 IPR014975 Protein of unknown function DUF1836 ALX04_RS01355 6d3641c327916683cfe8ff8c9968976b 281 Pfam PF01925 Sulfite exporter TauE/SafE 9 272 6.4E-49 T 28-03-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 ALX04_RS13285 e65a138b0b003ca3f83c77cee2cb4abe 91 Pfam PF15605 Bacterial toxin 28 19 80 1.8E-9 T 28-03-2018 IPR028948 Bacterial toxin 28 ALX04_RS06825 f97e6e5450ecab3128ca203bad84b117 304 Pfam PF07553 Host cell surface-exposed lipoprotein 255 302 2.2E-23 T 28-03-2018 IPR011434 Domain of unknown function DUF1535 ALX04_RS06825 f97e6e5450ecab3128ca203bad84b117 304 Pfam PF07553 Host cell surface-exposed lipoprotein 205 251 2.6E-21 T 28-03-2018 IPR011434 Domain of unknown function DUF1535 ALX04_RS10105 1fcc6f2eda3f349974b3d67ca325857a 160 Pfam PF01475 Ferric uptake regulator family 17 133 2.9E-33 T 28-03-2018 IPR002481 Ferric-uptake regulator GO:0003700|GO:0006355 ALX04_RS10105 1fcc6f2eda3f349974b3d67ca325857a 160 Gene3D G3DSA:1.10.10.10 1 87 1.9E-24 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS10105 1fcc6f2eda3f349974b3d67ca325857a 160 SUPERFAMILY SSF46785 8 138 5.26E-40 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS01360 b666583152544acf9a99ce155276db3b 126 Pfam PF07843 Protein of unknown function (DUF1634) 19 119 3.9E-32 T 28-03-2018 IPR012861 Protein of unknown function DUF1634 ALX04_RS09430 2924b32c1828122a91bc130d4d376964 1357 Gene3D G3DSA:3.10.20.320 1062 1170 1.4E-5 T 28-03-2018 ALX04_RS09430 2924b32c1828122a91bc130d4d376964 1357 Gene3D G3DSA:3.10.20.320 673 797 0.19 T 28-03-2018 ALX04_RS09430 2924b32c1828122a91bc130d4d376964 1357 Gene3D G3DSA:3.10.20.320 798 924 0.14 T 28-03-2018 ALX04_RS09430 2924b32c1828122a91bc130d4d376964 1357 TIGRFAM TIGR01167 LPXTG_anchor: LPXTG cell wall anchor domain 1323 1352 0.0014 T 28-03-2018 ALX04_RS12010 faa67dd25ffe55d9d5028b5b6458d257 263 Pfam PF01969 Protein of unknown function DUF111 4 259 5.7E-84 T 28-03-2018 IPR035108 LarC/UPF0272 ALX04_RS08335 9a9462b5a1fac65916fc33882d26f237 225 Pfam PF04474 Protein of unknown function (DUF554) 2 218 9.4E-61 T 28-03-2018 IPR007563 Protein of unknown function DUF554 ALX04_RS08620 d79c54826f83f61cfe679cb80edd64f4 284 SUPERFAMILY SSF103481 40 138 3.01E-6 T 28-03-2018 ALX04_RS08620 d79c54826f83f61cfe679cb80edd64f4 284 Pfam PF06800 Sugar transport protein 7 284 3.9E-87 T 28-03-2018 IPR010651 Sugar transport protein GO:0015144|GO:0016021|GO:0034219 ALX04_RS08620 d79c54826f83f61cfe679cb80edd64f4 284 SUPERFAMILY SSF103481 189 282 3.53E-7 T 28-03-2018 ALX04_RS10135 46e332cd43eb2dc63457c54f36624040 242 Pfam PF04172 LrgB-like family 15 237 9.7E-56 T 28-03-2018 IPR007300 CidB/LrgB family ALX04_RS01175 2a7ec4edf6165aa4c3337b004db6922a 310 Pfam PF00535 Glycosyl transferase family 2 6 153 1.2E-22 T 28-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 ALX04_RS01175 2a7ec4edf6165aa4c3337b004db6922a 310 SUPERFAMILY SSF53448 5 271 1.13E-36 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases ALX04_RS01175 2a7ec4edf6165aa4c3337b004db6922a 310 Gene3D G3DSA:3.90.550.10 4 302 6.0E-28 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases ALX04_RS13820 b6f34f2f1f2680960393b5ce6adab134 534 Pfam PF01943 Polysaccharide biosynthesis protein 10 305 3.9E-32 T 28-03-2018 IPR002797 Polysaccharide biosynthesis protein GO:0016020 ALX04_RS13820 b6f34f2f1f2680960393b5ce6adab134 534 Pfam PF14667 Polysaccharide biosynthesis C-terminal domain 357 505 1.1E-20 T 28-03-2018 IPR029303 Polysaccharide biosynthesis protein, C-terminal domain ALX04_RS09755 075150578a2e3a85ed62b2688f2c6d39 121 Pfam PF14079 Domain of unknown function (DUF4260) 16 117 3.0E-21 T 28-03-2018 IPR025356 Protein of unknown function DUF4260 ALX04_RS09370 36a0ca962da53f835b3fbca45ad921df 296 Gene3D G3DSA:3.40.50.720 4 296 1.0E-71 T 28-03-2018 ALX04_RS09370 36a0ca962da53f835b3fbca45ad921df 296 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 201 220 4.4E-8 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR ALX04_RS09370 36a0ca962da53f835b3fbca45ad921df 296 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 181 189 4.4E-8 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR ALX04_RS09370 36a0ca962da53f835b3fbca45ad921df 296 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 129 140 4.4E-8 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR ALX04_RS09370 36a0ca962da53f835b3fbca45ad921df 296 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 188 216 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 ALX04_RS09370 36a0ca962da53f835b3fbca45ad921df 296 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 129 140 1.2E-33 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR ALX04_RS09370 36a0ca962da53f835b3fbca45ad921df 296 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 175 191 1.2E-33 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR ALX04_RS09370 36a0ca962da53f835b3fbca45ad921df 296 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 222 239 1.2E-33 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR ALX04_RS09370 36a0ca962da53f835b3fbca45ad921df 296 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 53 70 1.2E-33 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR ALX04_RS09370 36a0ca962da53f835b3fbca45ad921df 296 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 201 220 1.2E-33 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR ALX04_RS09370 36a0ca962da53f835b3fbca45ad921df 296 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 257 277 1.2E-33 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR ALX04_RS09370 36a0ca962da53f835b3fbca45ad921df 296 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 61 292 1.0E-56 T 28-03-2018 ALX04_RS09370 36a0ca962da53f835b3fbca45ad921df 296 SUPERFAMILY SSF51735 51 293 4.6E-74 T 28-03-2018 IPR016040 NAD(P)-binding domain ALX04_RS07770 173383e7c62888e87c9f2a0d1a309b1f 257 Pfam PF01925 Sulfite exporter TauE/SafE 12 249 1.2E-34 T 28-03-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 ALX04_RS09470 e98f2cc4f15f207083ae4a6db79a3c05 234 Pfam PF13731 WxL domain surface cell wall-binding 28 232 1.4E-39 T 28-03-2018 IPR027994 WxL domain ALX04_RS06920 3ad3a4f33feb155d75d06c5c992103a2 157 Pfam PF05119 Phage terminase, small subunit 48 144 2.1E-25 T 28-03-2018 IPR006448 Putative phage terminase, small subunit, P27 family ALX04_RS06920 3ad3a4f33feb155d75d06c5c992103a2 157 TIGRFAM TIGR01558 sm_term_P27: putative phage terminase, small subunit, P27 family 40 153 4.4E-25 T 28-03-2018 IPR006448 Putative phage terminase, small subunit, P27 family ALX04_RS10595 7d59affe7e26d21797c72fecab5755a2 138 Gene3D G3DSA:2.10.290.10 67 138 3.6E-4 T 28-03-2018 ALX04_RS12050 de38d16b3869f7d47d12ab1598534470 399 TIGRFAM TIGR02358 thia_cytX: putative hydroxymethylpyrimidine transporter CytX 8 390 3.2E-155 T 28-03-2018 IPR012732 Hydroxymethylpyrimidine transporter CytX ALX04_RS12050 de38d16b3869f7d47d12ab1598534470 399 Pfam PF02133 Permease for cytosine/purines, uracil, thiamine, allantoin 9 335 9.7E-13 T 28-03-2018 IPR001248 Purine-cytosine permease GO:0005215|GO:0016020|GO:0055085 ALX04_RS09105 c1d7f7974a4aa7448271d3c137520656 320 Pfam PF02653 Branched-chain amino acid transport system / permease component 35 290 5.2E-43 T 28-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 ALX04_RS09105 c1d7f7974a4aa7448271d3c137520656 320 Gene3D G3DSA:1.10.3470.10 26 297 1.6E-34 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like ALX04_RS10730 af819fc1266f894b08bebb205b9a3492 245 SUPERFAMILY SSF46689 189 236 3.67E-11 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 ALX04_RS10730 af819fc1266f894b08bebb205b9a3492 245 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 204 219 5.3E-5 T 28-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 ALX04_RS10730 af819fc1266f894b08bebb205b9a3492 245 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 219 235 5.3E-5 T 28-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 ALX04_RS10730 af819fc1266f894b08bebb205b9a3492 245 Gene3D G3DSA:1.10.10.60 191 240 6.3E-13 T 28-03-2018 ALX04_RS10730 af819fc1266f894b08bebb205b9a3492 245 SMART SM00342 152 235 5.9E-19 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 ALX04_RS10730 af819fc1266f894b08bebb205b9a3492 245 Pfam PF12833 Helix-turn-helix domain 161 236 2.0E-17 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 ALX04_RS10730 af819fc1266f894b08bebb205b9a3492 245 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 189 231 - T 28-03-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 ALX04_RS10730 af819fc1266f894b08bebb205b9a3492 245 Gene3D G3DSA:1.10.10.60 76 190 1.0E-6 T 28-03-2018 ALX04_RS12355 e77e32ad515b7241af7a55a57656f356 90 Pfam PF03083 Sugar efflux transporter for intercellular exchange 11 86 2.2E-6 T 28-03-2018 IPR004316 SWEET sugar transporter GO:0016021 Reactome: R-HSA-70153 ALX04_RS10130 5f2b1c78259e070cb9076f9a18816450 139 Pfam PF03788 LrgA family 22 113 1.7E-21 T 28-03-2018 IPR005538 LrgA/CidA family GO:0016021 ALX04_RS05620 c215753253e0f261f3c18dbd5a3af1bd 339 SUPERFAMILY SSF51004 36 339 7.85E-45 T 28-03-2018 IPR011048 Cytochrome cd1-nitrite reductase-like, haem d1 domain ALX04_RS05620 c215753253e0f261f3c18dbd5a3af1bd 339 Gene3D G3DSA:2.130.10.10 1 339 1.5E-50 T 28-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 ALX04_RS05620 c215753253e0f261f3c18dbd5a3af1bd 339 Pfam PF10282 Lactonase, 7-bladed beta-propeller 5 339 1.6E-119 T 28-03-2018 IPR019405 Lactonase, 7-bladed beta propeller ALX04_RS02230 4ee8640ea5410dbfd7398bf8f3100f07 107 Pfam PF03413 Peptidase propeptide and YPEB domain 36 105 5.7E-6 T 28-03-2018 IPR025711 PepSY domain ALX04_RS10675 a6b74290a80a78871ae39a1356af5699 250 Pfam PF06738 Putative threonine/serine exporter 11 247 1.3E-67 T 28-03-2018 IPR010619 Putative threonine/serine exporter ALX04_RS08045 3c598f1bbb974194e2f8a9eda55e5df6 212 SUPERFAMILY SSF56935 44 178 3.11E-5 T 28-03-2018 ALX04_RS08510 d636da8d9af29be422fe44b371924f02 863 Pfam PF02687 FtsX-like permease family 365 449 1.1E-5 T 28-03-2018 IPR003838 ABC transporter permease protein domain GO:0016020 ALX04_RS08510 d636da8d9af29be422fe44b371924f02 863 Pfam PF02687 FtsX-like permease family 763 853 7.9E-8 T 28-03-2018 IPR003838 ABC transporter permease protein domain GO:0016020 ALX04_RS14135 468e153256be73cf25365cda47aec7b8 128 Pfam PF06115 Domain of unknown function (DUF956) 1 116 7.6E-53 T 28-03-2018 IPR010360 Protein of unknown function DUF956 ALX04_RS14135 468e153256be73cf25365cda47aec7b8 128 PIRSF PIRSF021265 1 123 4.0E-53 T 28-03-2018 IPR010360 Protein of unknown function DUF956 ALX04_RS12875 d21c3772e2d632a379c2aa3b9a6bf3ce 492 Pfam PF02687 FtsX-like permease family 341 486 2.4E-10 T 28-03-2018 IPR003838 ABC transporter permease protein domain GO:0016020 ALX04_RS06555 c55cdf580688a5f8159515774d37f44b 76 SMART SM00257 32 76 4.9E-12 T 28-03-2018 IPR018392 LysM domain ALX04_RS06555 c55cdf580688a5f8159515774d37f44b 76 Pfam PF01476 LysM domain 33 75 6.3E-11 T 28-03-2018 IPR018392 LysM domain ALX04_RS06555 c55cdf580688a5f8159515774d37f44b 76 Gene3D G3DSA:3.10.350.10 29 75 5.0E-12 T 28-03-2018 ALX04_RS06555 c55cdf580688a5f8159515774d37f44b 76 SUPERFAMILY SSF54106 30 75 5.89E-11 T 28-03-2018 IPR018392 LysM domain ALX04_RS04925 d90e988c42862aa3ba6ae3870f7d1712 85 Gene3D G3DSA:1.10.10.10 37 85 0.0015 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS15180 fac5437fdfe07c6d3c7824379826ec6e 252 Pfam PF04794 YdjC-like protein 4 240 3.7E-48 T 28-03-2018 IPR006879 Carbohydrate deacetylase YdjC-like ALX04_RS15180 fac5437fdfe07c6d3c7824379826ec6e 252 SUPERFAMILY SSF88713 1 252 6.23E-61 T 28-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 ALX04_RS15180 fac5437fdfe07c6d3c7824379826ec6e 252 Gene3D G3DSA:3.20.20.370 1 252 4.5E-62 T 28-03-2018 ALX04_RS06930 100c5f8fb406f6aaa66350e33d1c0b8d 112 TIGRFAM TIGR01563 gp16_SPP1: putative phage head-tail adaptor 9 105 4.7E-8 T 28-03-2018 IPR008767 Bacteriophage SPP1, head-tail adaptor ALX04_RS06930 100c5f8fb406f6aaa66350e33d1c0b8d 112 Pfam PF05521 Phage head-tail joining protein 10 104 1.6E-13 T 28-03-2018 IPR008767 Bacteriophage SPP1, head-tail adaptor ALX04_RS15220 4134b3145bebe5a38d735cf6a49d8e52 186 Gene3D G3DSA:1.10.10.60 1 45 1.6E-15 T 28-03-2018 ALX04_RS15220 4134b3145bebe5a38d735cf6a49d8e52 186 Gene3D G3DSA:1.10.10.60 46 175 1.5E-9 T 28-03-2018 ALX04_RS15220 4134b3145bebe5a38d735cf6a49d8e52 186 Pfam PF00440 Bacterial regulatory proteins, tetR family 12 57 3.8E-13 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 ALX04_RS15220 4134b3145bebe5a38d735cf6a49d8e52 186 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 33 56 8.2E-8 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 ALX04_RS15220 4134b3145bebe5a38d735cf6a49d8e52 186 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 12 25 8.2E-8 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 ALX04_RS15220 4134b3145bebe5a38d735cf6a49d8e52 186 SUPERFAMILY SSF46689 1 67 1.25E-16 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 ALX04_RS00535 23151c3d49bfd7e2b67ccc9da520bd17 636 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 5 326 7.7E-44 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ALX04_RS00535 23151c3d49bfd7e2b67ccc9da520bd17 636 Gene3D G3DSA:3.50.50.60 2 129 1.6E-16 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ALX04_RS00535 23151c3d49bfd7e2b67ccc9da520bd17 636 SUPERFAMILY SSF51905 153 337 1.14E-12 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ALX04_RS00535 23151c3d49bfd7e2b67ccc9da520bd17 636 SUPERFAMILY SSF51905 3 208 2.87E-28 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ALX04_RS00535 23151c3d49bfd7e2b67ccc9da520bd17 636 Gene3D G3DSA:3.50.50.60 130 337 6.7E-20 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ALX04_RS07640 44a23b17c73595d89c654fb76dfc488d 65 Pfam PF11151 Protein of unknown function (DUF2929) 10 56 2.9E-5 T 28-03-2018 IPR021324 Protein of unknown function DUF2929 ALX04_RS13400 c68579375ef69c4ebebd3c5ab2210974 458 Gene3D G3DSA:1.20.1170.10 140 421 1.4E-7 T 28-03-2018 ALX04_RS13400 c68579375ef69c4ebebd3c5ab2210974 458 Pfam PF13437 HlyD family secretion protein 319 432 1.7E-11 T 28-03-2018 ALX04_RS13400 c68579375ef69c4ebebd3c5ab2210974 458 TIGRFAM TIGR01000 bacteriocin_acc: bacteriocin secretion accessory protein 1 458 5.4E-175 T 28-03-2018 IPR005696 Mesentericin y105 secretion protein GO:0005215|GO:0006810 ALX04_RS10840 e13d892b1ab148a781f8948a5a7496c0 89 Pfam PF02583 Metal-sensitive transcriptional repressor 10 81 3.2E-21 T 28-03-2018 IPR003735 Metal-sensitive transcriptional repressor GO:0003677|GO:0006355|GO:0046872 ALX04_RS01300 daae16d675dda2dcc3ead94f016f0728 397 Pfam PF01594 AI-2E family transporter 24 355 6.4E-78 T 28-03-2018 IPR002549 Transmembrane protein TqsA-like ALX04_RS09835 3f82cfafc103db4b009d6a9c6bb2d033 116 Pfam PF05437 Branched-chain amino acid transport protein (AzlD) 13 110 5.1E-23 T 28-03-2018 IPR008407 Branched-chain amino acid transport, AzlD ALX04_RS12555 ba8bcedb9b0d23d846d5d2e663f102a2 471 Pfam PF03577 Peptidase family C69 7 405 1.4E-155 T 28-03-2018 IPR005322 Peptidase C69, dipeptidase A GO:0006508|GO:0016805 ALX04_RS12555 ba8bcedb9b0d23d846d5d2e663f102a2 471 Gene3D G3DSA:3.60.60.10 7 331 1.2E-46 T 28-03-2018 ALX04_RS15460 370dcf897fec1996e7ea97d44783944f 99 Pfam PF03609 PTS system sorbose-specific iic component 3 71 4.7E-15 T 28-03-2018 IPR004700 Phosphotransferase system, mannose/fructose/sorbose family, IIC subunit GO:0009401|GO:0016021 ALX04_RS02615 9ba61f97e8cc8389db6600f0fa31b121 58 Pfam PF11240 Protein of unknown function (DUF3042) 1 54 6.0E-28 T 28-03-2018 IPR021402 Protein of unknown function DUF3042 ALX04_RS10725 c7ca02b2b343879664e836573328009a 269 Pfam PF13731 WxL domain surface cell wall-binding 34 267 1.1E-41 T 28-03-2018 IPR027994 WxL domain ALX04_RS12000 33de926a05b3641261640060f163684a 424 Pfam PF09861 Domain of unknown function (DUF2088) 8 213 2.3E-76 T 28-03-2018 IPR018657 LarA-like, N-terminal ALX04_RS03235 0b5a6f112bf7ede26eeacb2793f08af9 305 Pfam PF01040 UbiA prenyltransferase family 25 279 1.6E-19 T 28-03-2018 IPR000537 UbiA prenyltransferase family GO:0016021|GO:0016765 ALX04_RS03235 0b5a6f112bf7ede26eeacb2793f08af9 305 PIRSF PIRSF005355 2 304 4.6E-33 T 28-03-2018 IPR026046 UbiA prenyltransferase domain containing protein 1 GO:0004659 Reactome: R-HSA-6806664 ALX04_RS09780 1d5f8b20e4bfa23d388b1826909ffb0e 360 Pfam PF01594 AI-2E family transporter 22 333 1.3E-40 T 28-03-2018 IPR002549 Transmembrane protein TqsA-like ALX04_RS15625 cd4036ea6eadce0326b1e8e0156f8f3d 92 Gene3D G3DSA:1.10.10.10 1 59 6.1E-5 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS15625 cd4036ea6eadce0326b1e8e0156f8f3d 92 Pfam PF09862 Protein of unknown function (DUF2089) 2 83 8.1E-16 T 28-03-2018 IPR018658 Protein of unknown function DUF2089 ALX04_RS09330 0f6f665c504e45c715a72476121f4d43 117 Pfam PF04126 Cyclophilin-like 2 100 3.8E-11 T 28-03-2018 IPR025658 Cyclophilin TM1367-like domain ALX04_RS09330 0f6f665c504e45c715a72476121f4d43 117 SUPERFAMILY SSF50891 3 116 1.71E-23 T 28-03-2018 IPR029000 Cyclophilin-like domain ALX04_RS06740 573cf292d180edbda3c97230fea5465e 144 Pfam PF11672 zinc-finger-containing domain 18 131 7.5E-32 T 28-03-2018 IPR021686 Protein of unkown function DUF3268 ALX04_RS04995 76c2dfb148b99cf048e7b80887f0af92 232 Gene3D G3DSA:2.60.40.1240 92 232 7.1E-10 T 28-03-2018 IPR029050 Immunoprotective extracellular, immunoglobulin-like domain ALX04_RS04795 0b7b11e120f33bb69a7fbd68541e82af 589 Pfam PF05709 Phage tail protein 29 584 1.6E-16 T 28-03-2018 IPR008841 Siphovirus-type tail component ALX04_RS11355 1b0e6b5d5fd184955ebd8f3ec1091998 81 Pfam PF04226 Transglycosylase associated protein 33 76 3.9E-9 T 28-03-2018 IPR007341 Transglycosylase-associated protein GO:0016021 ALX04_RS12900 2428b275b09574560f1a9e1ee22f06f0 210 Pfam PF01476 LysM domain 29 70 2.9E-12 T 28-03-2018 IPR018392 LysM domain ALX04_RS12900 2428b275b09574560f1a9e1ee22f06f0 210 SUPERFAMILY SSF54106 27 72 7.72E-9 T 28-03-2018 IPR018392 LysM domain ALX04_RS12900 2428b275b09574560f1a9e1ee22f06f0 210 SMART SM00257 28 72 1.3E-11 T 28-03-2018 IPR018392 LysM domain ALX04_RS12900 2428b275b09574560f1a9e1ee22f06f0 210 Gene3D G3DSA:3.10.350.10 22 77 3.0E-15 T 28-03-2018 ALX04_RS15950 0a384203d9e613a32f646430fc743174 686 Pfam PF03389 MobA/MobL family 17 240 1.5E-82 T 28-03-2018 IPR005053 MobA/MobL protein ALX04_RS03500 57f341a675f4cc96859978f2e9877b36 128 Pfam PF17255 Family of unknown function (DUF5322) 4 123 2.0E-20 T 28-03-2018 IPR020215 Pore-forming protein, EbsA ALX04_RS05820 e98aaffff7ce4b64d42042d445afe82a 218 Pfam PF09335 SNARE associated Golgi protein 46 174 1.6E-21 T 28-03-2018 IPR032816 SNARE associated Golgi protein ALX04_RS10415 d76ebb64dd8d1a5f5de7ca29b89dd579 81 Pfam PF13376 Bacteriocin-protection, YdeI or OmpD-Associated 16 61 5.2E-10 T 28-03-2018 ALX04_RS02250 a01b6c54a64769d271df2c7e8bca6f5a 62 Pfam PF12669 Virus attachment protein p12 family 6 41 5.9E-9 T 28-03-2018 ALX04_RS00160 5a1b2d9f0ecd2589ba6ad705448fc829 233 Pfam PF03591 AzlC protein 16 157 2.7E-40 T 28-03-2018 IPR011606 Branched-chain amino acid transport, permease ALX04_RS05675 5daa8b34b5de2f21683ea7acc911e5f8 166 Gene3D G3DSA:3.30.70.100 69 163 4.2E-7 T 28-03-2018 ALX04_RS05675 5daa8b34b5de2f21683ea7acc911e5f8 166 SUPERFAMILY SSF54909 74 147 3.26E-10 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel ALX04_RS04145 92a8cf59866323971d00a08486372894 424 Gene3D G3DSA:3.40.1710.10 31 246 1.9E-25 T 28-03-2018 ALX04_RS00245 4e8ad16b135a8ab442ecfd917e2798e4 345 Pfam PF03816 Cell envelope-related transcriptional attenuator domain 107 251 8.5E-43 T 28-03-2018 IPR004474 Cell envelope-related transcriptional attenuator domain ALX04_RS00245 4e8ad16b135a8ab442ecfd917e2798e4 345 TIGRFAM TIGR00350 lytR_cpsA_psr: cell envelope-related function transcriptional attenuator common domain 106 252 3.8E-39 T 28-03-2018 IPR004474 Cell envelope-related transcriptional attenuator domain ALX04_RS12835 ffbc019ac44ad13576b50511345479a5 356 Pfam PF03816 Cell envelope-related transcriptional attenuator domain 76 221 2.0E-48 T 28-03-2018 IPR004474 Cell envelope-related transcriptional attenuator domain ALX04_RS12835 ffbc019ac44ad13576b50511345479a5 356 TIGRFAM TIGR00350 lytR_cpsA_psr: cell envelope-related function transcriptional attenuator common domain 75 220 2.9E-45 T 28-03-2018 IPR004474 Cell envelope-related transcriptional attenuator domain ALX04_RS06615 b656f76ca38a80c4e3b20220c414786f 372 Pfam PF06605 Prophage endopeptidase tail 29 324 1.3E-40 T 28-03-2018 IPR010572 Prophage tail endopeptidase ALX04_RS00205 443b989a0c7b139b7015d65e394be755 240 Pfam PF16069 Domain of unknown function (DUF4811) 23 174 2.0E-56 T 28-03-2018 IPR032083 Protein of unknown function DUF4811 ALX04_RS01430 2b9a6ddd54264be824604a0abac7efba 351 TIGRFAM TIGR00374 TIGR00374: TIGR00374 family protein 29 330 2.4E-23 T 28-03-2018 IPR022791 Lysylphosphatidylglycerol synthetase/glycosyltransferase AglD ALX04_RS01430 2b9a6ddd54264be824604a0abac7efba 351 Pfam PF03706 Lysylphosphatidylglycerol synthase TM region 10 324 1.3E-48 T 28-03-2018 IPR022791 Lysylphosphatidylglycerol synthetase/glycosyltransferase AglD ALX04_RS10220 45db74da5053fa04ee51a19caee02950 194 Pfam PF06736 Protein of unknown function (DUF1211) 8 94 2.5E-20 T 28-03-2018 IPR010617 Endosomal/lysomomal potassium channel TMEM175 GO:0005267 ALX04_RS11055 67d812823b2eac4883f32ba3851f3694 122 Gene3D G3DSA:2.30.110.10 1 122 1.9E-11 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 ALX04_RS11055 67d812823b2eac4883f32ba3851f3694 122 SUPERFAMILY SSF50475 1 120 7.85E-31 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 ALX04_RS15235 3beb8fa839905a13ca8b8cb45b4380bc 104 SUPERFAMILY SSF103481 4 102 1.96E-19 T 28-03-2018 ALX04_RS15235 3beb8fa839905a13ca8b8cb45b4380bc 104 Pfam PF00893 Small Multidrug Resistance protein 1 93 2.2E-27 T 28-03-2018 IPR000390 Small multidrug resistance protein family GO:0016021 ALX04_RS00770 6fdcfe672b05c0e90951d55b5932ae53 323 Pfam PF03547 Membrane transport protein 175 316 6.5E-10 T 28-03-2018 IPR004776 Membrane transport protein GO:0016021|GO:0055085 ALX04_RS00770 6fdcfe672b05c0e90951d55b5932ae53 323 Pfam PF03547 Membrane transport protein 8 152 8.6E-18 T 28-03-2018 IPR004776 Membrane transport protein GO:0016021|GO:0055085 ALX04_RS03555 ff074cf2bbad70486b9e4901a6963399 241 Pfam PF09860 Uncharacterized protein conserved in bacteria (DUF2087) 167 235 2.0E-22 T 28-03-2018 IPR018656 Domain of unknown function DUF2087 ALX04_RS07585 43dd4b2f80e22bc97bb6edac02989627 168 Pfam PF11391 Protein of unknown function (DUF2798) 14 71 1.4E-12 T 28-03-2018 IPR021529 Protein of unknown function DUF2798 ALX04_RS06000 b5283978937cbc3a49e249df87c7eaec 98 Hamap MF_01448 UPF0473 protein . 9 93 22.339 T 28-03-2018 IPR009711 Uncharacterised protein family UPF0473 ALX04_RS06000 b5283978937cbc3a49e249df87c7eaec 98 Pfam PF06949 Protein of unknown function (DUF1292) 18 91 1.3E-17 T 28-03-2018 IPR009711 Uncharacterised protein family UPF0473 ALX04_RS12760 e03ae79683f0fcfc4e02022dac5243c9 146 Pfam PF02082 Transcriptional regulator 1 81 1.8E-17 T 28-03-2018 IPR000944 Transcription regulator Rrf2-type ALX04_RS12760 e03ae79683f0fcfc4e02022dac5243c9 146 SUPERFAMILY SSF46785 5 132 2.04E-29 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS12760 e03ae79683f0fcfc4e02022dac5243c9 146 Gene3D G3DSA:1.10.10.10 1 146 5.9E-25 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS15700 577e44c87b9a81cce5c086c8238c90c6 140 Pfam PF01609 Transposase DDE domain 1 131 3.1E-18 T 28-03-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 ALX04_RS00840 b53711cc5eb7603d27414eaafe651b9e 213 Gene3D G3DSA:1.10.530.10 56 210 2.3E-39 T 28-03-2018 ALX04_RS00840 b53711cc5eb7603d27414eaafe651b9e 213 SMART SM00047 56 211 9.3E-43 T 28-03-2018 IPR002901 Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like domain GO:0004040 ALX04_RS00840 b53711cc5eb7603d27414eaafe651b9e 213 Pfam PF01832 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase 73 206 1.0E-24 T 28-03-2018 IPR002901 Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like domain GO:0004040 ALX04_RS00840 b53711cc5eb7603d27414eaafe651b9e 213 PRINTS PR01002 Flagellar protein FlgJ signature 168 187 3.0E-12 T 28-03-2018 ALX04_RS00840 b53711cc5eb7603d27414eaafe651b9e 213 PRINTS PR01002 Flagellar protein FlgJ signature 86 104 3.0E-12 T 28-03-2018 ALX04_RS00840 b53711cc5eb7603d27414eaafe651b9e 213 PRINTS PR01002 Flagellar protein FlgJ signature 188 206 3.0E-12 T 28-03-2018 ALX04_RS03085 1b765bde6a63fa0f2cd257552c4de054 241 Pfam PF04474 Protein of unknown function (DUF554) 3 231 2.5E-57 T 28-03-2018 IPR007563 Protein of unknown function DUF554 ALX04_RS15450 cb51bfbc35af735ddc8b6f8120168d83 183 Pfam PF03609 PTS system sorbose-specific iic component 5 182 1.9E-39 T 28-03-2018 IPR004700 Phosphotransferase system, mannose/fructose/sorbose family, IIC subunit GO:0009401|GO:0016021 ALX04_RS13830 a071458892fb5f0df5c32cc29abe7f2e 132 Pfam PF04977 Septum formation initiator 48 123 2.0E-18 T 28-03-2018 IPR007060 Septum formation initiator FtsL/DivIC GO:0007049 ALX04_RS06965 ed862daa945142283a6155ef53efbbe0 67 Gene3D G3DSA:1.10.260.40 9 67 2.5E-4 T 28-03-2018 ALX04_RS14265 0e20ff99cd74ee687136702147ddd21e 181 Pfam PF05991 YacP-like NYN domain 6 168 2.2E-48 T 28-03-2018 IPR010298 Protein of unknown function DUF901 ALX04_RS06380 3b286d6f5d260b2def8af1fcaf73800b 75 Pfam PF11184 Protein of unknown function (DUF2969) 2 73 5.5E-25 T 28-03-2018 IPR021351 Protein of unknown function DUF2969 ALX04_RS09920 04409dbd628959a76bee69862e598576 983 Pfam PF09586 Bacterial membrane protein YfhO 15 958 1.4E-158 T 28-03-2018 IPR018580 Uncharacterised protein family YfhO ALX04_RS12495 d8815a8d71e9f8f88934c8a9f10760f5 219 Pfam PF02361 Cobalt transport protein 8 188 3.4E-11 T 28-03-2018 IPR003339 ABC/ECF transporter, transmembrane component ALX04_RS09970 ca6f7063b20a9045f1a75b1e9b9e61ea 212 Pfam PF08006 Protein of unknown function (DUF1700) 2 187 6.1E-14 T 28-03-2018 IPR012963 Protein of unknown function DUF1700 ALX04_RS07800 836b01272441051db8fbceab98a87c63 369 Pfam PF04657 Putative inner membrane exporter, YdcZ 50 189 4.2E-41 T 28-03-2018 IPR006750 Putative inner membrane exporter, YdcZ ALX04_RS07800 836b01272441051db8fbceab98a87c63 369 Pfam PF04657 Putative inner membrane exporter, YdcZ 226 365 8.4E-40 T 28-03-2018 IPR006750 Putative inner membrane exporter, YdcZ ALX04_RS08355 0fad6758fb7095bc21a03ed682622ae9 355 Pfam PF02687 FtsX-like permease family 267 350 4.9E-6 T 28-03-2018 IPR003838 ABC transporter permease protein domain GO:0016020 ALX04_RS04785 dc474d1ba96b3e476ebbf960884958c1 929 Gene3D G3DSA:1.10.10.10 801 929 1.8E-4 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain ALX04_RS06805 97a83c4d84c88122f35778b7591dfc54 137 Pfam PF06114 IrrE N-terminal-like domain 24 104 7.8E-11 T 28-03-2018 IPR010359 IrrE N-terminal-like domain ALX04_RS11495 f5a140dd61213e20214a07a3df52edc7 160 Pfam PF13673 Acetyltransferase (GNAT) domain 44 126 4.0E-13 T 28-03-2018 IPR000182 GNAT domain GO:0008080 ALX04_RS11495 f5a140dd61213e20214a07a3df52edc7 160 Gene3D G3DSA:3.40.630.30 1 149 9.4E-24 T 28-03-2018 ALX04_RS11495 f5a140dd61213e20214a07a3df52edc7 160 SUPERFAMILY SSF55729 1 135 1.89E-22 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase ALX04_RS12115 b53a3c746e27433107e1f0b5afb34a59 64 Pfam PF04024 PspC domain 6 58 5.5E-19 T 28-03-2018 IPR007168 Phage shock protein, PspC, N-terminal ALX04_RS02710 935585a5857c2f74d59671e5b78512e7 152 Pfam PF03780 Asp23 family, cell envelope-related function 16 121 1.0E-32 T 28-03-2018 IPR005531 Alkaline shock protein Asp23 ALX04_RS06585 d667c88d74482a89403788dab323ea9b 48 Pfam PF09693 Phage uncharacterised protein (Phage_XkdX) 12 42 1.0E-7 T 28-03-2018 IPR010022 Protein of unknown function XkdX ALX04_RS10570 3571c100e9006371296200a577d81ba0 225 Pfam PF01988 VIT family 14 221 4.2E-51 T 28-03-2018 IPR008217 Ccc1 family ALX04_RS04975 2b9d142375aae1886190694cfa02f1c4 73 Gene3D G3DSA:1.10.260.40 2 73 8.7E-6 T 28-03-2018 ALX04_RS05500 c26a8fc5df48416039a51862aa1c32a3 86 Pfam PF02325 YGGT family 9 75 6.5E-23 T 28-03-2018 IPR003425 CCB3/YggT GO:0016020 ALX04_RS04175 0977229a5bbe3e67d6ced2e73f33e91d 193 Pfam PF02378 Phosphotransferase system, EIIC 43 111 2.0E-9 T 28-03-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 ALX04_RS06645 db463ad70552e226e8e81c9ded3cee0a 134 Pfam PF12691 Minor capsid protein from bacteriophage 1 127 6.6E-28 T 28-03-2018 IPR024411 Minor capsid protein, bacteriophage ALX04_RS06650 a7f77c4a1e20b507520ae87c194a1c38 115 Pfam PF11114 Minor capsid protein 4 114 5.2E-36 T 28-03-2018 IPR021080 Minor capsid protein ALX04_RS13380 0dc9caf57b1e21e38cced2d3227f9e54 257 Pfam PF02517 CAAX protease self-immunity 94 198 7.1E-13 T 28-03-2018 IPR003675 CAAX amino terminal protease GO:0016020 Reactome: R-HSA-5689880 ALX04_RS15730 a573bc731ba7771af0eecfd3008590ef 297 Pfam PF13612 Transposase DDE domain 112 263 1.6E-28 T 28-03-2018 IPR025668 Transposase DDE domain ALX04_RS14980 605ad50126aae8cf59ead77aedc9f404 170 Pfam PF04892 VanZ like family 39 155 2.4E-12 T 28-03-2018 IPR006976 VanZ-like ALX04_RS07620 f3058aee3b9cbca13045a12a3ec71283 384 Pfam PF11770 GRB2-binding adapter (GAPT) 6 95 2.2E-4 T 28-03-2018 IPR021082 Protein GAPT GO:0016021 ALX04_RS13405 cb7aadaa0d64d5c142c6447ac5f8d014 229 Pfam PF02517 CAAX protease self-immunity 126 220 4.2E-15 T 28-03-2018 IPR003675 CAAX amino terminal protease GO:0016020 Reactome: R-HSA-5689880 ALX04_RS15340 89976dce98fa836ad4feeec900b21382 140 Pfam PF03780 Asp23 family, cell envelope-related function 10 115 1.4E-32 T 28-03-2018 IPR005531 Alkaline shock protein Asp23 ALX04_RS15705 876f7ea8d7baf77f08ac91e13ebdf2aa 391 Pfam PF00872 Transposase, Mutator family 6 363 1.4E-109 T 28-03-2018 IPR001207 Transposase, mutator type GO:0003677|GO:0004803|GO:0006313 ALX04_RS03105 d62a91fbdfb7ddf06c13246a38f6c644 183 SUPERFAMILY SSF46689 5 70 9.71E-11 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 ALX04_RS03105 d62a91fbdfb7ddf06c13246a38f6c644 183 Gene3D G3DSA:1.10.357.10 2 183 1.2E-13 T 28-03-2018 ALX04_RS03005 39d0b209b72f33dc599b530dd1aa04d7 120 Pfam PF07853 Protein of unknown function (DUF1648) 11 56 5.6E-10 T 28-03-2018 IPR012867 Domain of unknown function DUF1648 ALX04_RS09165 7db0d0b2ef78a5e76a8d34d05ff76781 188 Pfam PF03596 Cadmium resistance transporter 13 186 1.5E-14 T 28-03-2018 IPR004676 Cadmium resistance transporter ALX04_RS01850 8e174a1e5e3be148265e1a2c86e0b9ff 171 Pfam PF04138 GtrA-like protein 32 148 6.6E-18 T 28-03-2018 IPR007267 GtrA-like protein GO:0000271|GO:0006810|GO:0016021 ALX04_RS02175 90b24f666fb1624cd8331b1e3813a276 123 TIGRFAM TIGR01167 LPXTG_anchor: LPXTG cell wall anchor domain 89 122 1.7E-4 T 28-03-2018 ALX04_RS10790 6889ca2428d6f169581e9cdfa9f65063 103 Pfam PF10078 Uncharacterized protein conserved in bacteria (DUF2316) 1 89 9.0E-38 T 28-03-2018 IPR018757 Protein of unknown function DUF2316 ALX04_RS03630 b9cfd66c6d462e5b93613c66fff8848e 245 Pfam PF06210 Protein of unknown function (DUF1003) 113 210 5.7E-38 T 28-03-2018 IPR010406 Protein of unknown function DUF1003 ALX04_RS10455 354cbe20ea31e6326e52ac344ac43127 394 Pfam PF10087 Uncharacterized protein conserved in bacteria (DUF2325) 277 368 1.5E-9 T 28-03-2018 IPR016772 Uncharacterised conserved protein UCP020408 ALX04_RS03185 101c0b7b4aa8a4a2244836f36d82c53f 121 Pfam PF05656 Protein of unknown function (DUF805) 13 118 3.9E-21 T 28-03-2018 IPR008523 Protein of unknown function DUF805 GO:0016021 ALX04_RS14125 6834e6c0bcdc8089d0e8016324ece2c2 268 Pfam PF03609 PTS system sorbose-specific iic component 5 238 8.1E-72 T 28-03-2018 IPR004700 Phosphotransferase system, mannose/fructose/sorbose family, IIC subunit GO:0009401|GO:0016021 ALX04_RS03850 cbb33ff4f1a78d8e995cb3f45859a0d0 214 Pfam PF09911 Uncharacterized protein conserved in bacteria (DUF2140) 23 208 9.1E-61 T 28-03-2018 IPR018672 Protein of unknown function DUF2140 ALX04_RS14870 d7cc42bab6149fccb4f43ec9a8f47ea5 709 Pfam PF00999 Sodium/hydrogen exchanger family 6 410 4.8E-49 T 28-03-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 ALX04_RS12330 eb1dc33c5882ffb925bfbd93bb91a09e 276 PIRSF PIRSF009136 5 272 2.4E-119 T 28-03-2018 IPR016546 Maltodextrose utilization protein MalA ALX04_RS10250 7072c4e823ef4ee15e5c747209ef52ca 348 Pfam PF01594 AI-2E family transporter 16 329 1.3E-35 T 28-03-2018 IPR002549 Transmembrane protein TqsA-like ALX04_RS14775 3a937435044c9bf5e1aa1383d445b8da 243 SUPERFAMILY SSF56112 23 198 6.12E-8 T 28-03-2018 IPR011009 Protein kinase-like domain ALX04_RS09865 529584dd893b2fcdbb3f2f42e329f52d 229 Pfam PF06912 Protein of unknown function (DUF1275) 16 212 3.7E-37 T 28-03-2018 IPR010699 Protein of unknown function DUF1275 ALX04_RS07690 4ffb9ca795d090242698c4cbc830d5ea 120 Gene3D G3DSA:3.10.450.150 2 104 1.4E-11 T 28-03-2018 ALX04_RS08415 12bd1c623820c6b9804ef6642089b1ae 166 Pfam PF16069 Domain of unknown function (DUF4811) 26 165 2.9E-39 T 28-03-2018 IPR032083 Protein of unknown function DUF4811 ALX04_RS06560 cea89e981ce31dbdaf8e03871cde66d7 124 Pfam PF04531 Bacteriophage holin 17 69 8.8E-8 T 28-03-2018 IPR006485 Bacteriophage holin ALX04_RS06550 71c85dbd2b1c098c0c59b042b64e5f2e 292 Pfam PF07751 Abi-like protein 35 216 2.4E-43 T 28-03-2018 IPR011664 Abortive infection system protein AbiD/AbiF-like ALX04_RS07120 2bde9e868a70bfd8ea4959f97c55c1e4 186 Pfam PF07155 ECF-type riboflavin transporter, S component 7 173 8.2E-17 T 28-03-2018 IPR009825 ECF transporter, substrate-specific component-like GO:0016020 ALX04_RS11985 2a53810e0043b13cde171d86aa3f674b 273 Pfam PF02361 Cobalt transport protein 57 240 6.5E-16 T 28-03-2018 IPR003339 ABC/ECF transporter, transmembrane component