locus-tag	class	description
LOCK908_RS00010	COG0592	DNA-directed DNA polymerase activity
LOCK908_RS00020	COG2501	S4 domain
LOCK908_RS00030	COG0187	DNA topoisomerase II activity
LOCK908_RS00070	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
LOCK908_RS00085	COG0629	single-stranded DNA binding
LOCK908_RS00095	COG0693	protein deglycase activity
LOCK908_RS00100	COG1271	oxidase subunit
LOCK908_RS00105	COG1294	oxidase, subunit
LOCK908_RS00120	COG1266	CAAX protease self-immunity
LOCK908_RS00140	COG4555	ABC transporter
LOCK908_RS00145	COG0004	ammonium transporteR
LOCK908_RS00165	COG0577	efflux transmembrane transporter activity
LOCK908_RS00165	COG1136	(ABC) transporter
LOCK908_RS00175	COG0561	phosphatase activity
LOCK908_RS00195	COG0110	maltose O-acetyltransferase activity
LOCK908_RS00230	COG3409	Peptidoglycan-binding domain 1 protein
LOCK908_RS00245	COG3250	beta-galactosidase activity
LOCK908_RS00250	COG1511	domain protein
LOCK908_RS00250	COG4372	Transposase
LOCK908_RS00250	COG1196	nuclear chromosome segregation
LOCK908_RS00255	COG0800	Aldolase
LOCK908_RS00260	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LOCK908_RS00265	COG1904	glucuronate isomerase
LOCK908_RS00270	COG1312	Catalyzes the dehydration of D-mannonate
LOCK908_RS00275	COG0246	Mannitol dehydrogenase
LOCK908_RS00315	COG2814	Major facilitator Superfamily
LOCK908_RS00345	COG1033	growth of symbiont in host cell
LOCK908_RS00345	COG2409	Drug exporters of the RND superfamily
LOCK908_RS00350	COG1309	transcriptional regulator
LOCK908_RS00405	COG2217	Heavy metal translocating P-type atpase
LOCK908_RS00415	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
LOCK908_RS00430	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
LOCK908_RS00430	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LOCK908_RS00430	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LOCK908_RS00435	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LOCK908_RS00435	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
LOCK908_RS00435	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LOCK908_RS00440	COG0383	alpha-mannosidase activity
LOCK908_RS00450	COG2723	6-phospho-beta-galactosidase activity
LOCK908_RS00455	COG1940	carbohydrate kinase activity
LOCK908_RS00460	COG0159	tryptophan synthase activity
LOCK908_RS00510	COG1131	(ABC) transporter
LOCK908_RS00525	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
LOCK908_RS00545	COG0019	diaminopimelate decarboxylase activity
LOCK908_RS00550	COG0527	aspartate kinase activity
LOCK908_RS00560	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
LOCK908_RS00570	COG0494	nUDIX hydrolase
LOCK908_RS00610	COG1131	(ABC) transporter
LOCK908_RS00625	COG0305	Participates in initiation and elongation during chromosome replication
LOCK908_RS00635	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LOCK908_RS00635	COG1263	PTS System
LOCK908_RS00640	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
LOCK908_RS00655	COG1309	transcriptional regulator
LOCK908_RS00660	COG1136	(ABC) transporter
LOCK908_RS00660	COG0577	efflux transmembrane transporter activity
LOCK908_RS00680	COG2217	Heavy metal translocating P-type atpase
LOCK908_RS00685	COG0640	Transcriptional regulator
LOCK908_RS00695	COG3620	sequence-specific DNA binding
LOCK908_RS00705	COG1131	(ABC) transporter
LOCK908_RS00760	COG2814	Major facilitator Superfamily
LOCK908_RS00770	COG5002	protein histidine kinase activity
LOCK908_RS00770	COG3850	Histidine kinase
LOCK908_RS00775	COG0745	RESPONSE REGULATOR receiver
LOCK908_RS00780	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
LOCK908_RS00790	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
LOCK908_RS00795	COG1447	Phosphotransferase system cellobiose-specific component IIA
LOCK908_RS00805	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
LOCK908_RS00810	COG2723	6-phospho-beta-galactosidase activity
LOCK908_RS00815	COG2188	Transcriptional regulator
LOCK908_RS00835	COG2252	PERMEase
LOCK908_RS00845	COG0346	lactoylglutathione lyase activity
LOCK908_RS00900	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
LOCK908_RS00915	COG1070	Carbohydrate kinase
LOCK908_RS00920	COG0191	fructose-bisphosphate aldolase activity
LOCK908_RS00940	COG0477	Major facilitator Superfamily
LOCK908_RS00975	COG1131	(ABC) transporter
LOCK908_RS00980	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
LOCK908_RS00985	COG4166	transmembrane transport
LOCK908_RS01005	COG1131	(ABC) transporter
LOCK908_RS01030	COG0446	pyridine nucleotide-disulphide oxidoreductase
LOCK908_RS01070	COG0716	FMN binding
LOCK908_RS01085	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LOCK908_RS01095	COG2261	transglycosylase associated protein
LOCK908_RS01110	COG1302	Protein conserved in bacteria
LOCK908_RS01145	COG3442	glutamine amidotransferase
LOCK908_RS01165	COG1192	Involved in chromosome partitioning
LOCK908_RS01170	COG1475	DNA binding
LOCK908_RS01175	COG4481	Protein conserved in bacteria
LOCK908_RS01180	COG0012	GTP binding
LOCK908_RS01190	COG0517	IMP dehydrogenase activity
LOCK908_RS01190	COG0516	GMP reductase activity
LOCK908_RS01210	COG1686	Belongs to the peptidase S11 family
LOCK908_RS01215	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
LOCK908_RS01225	COG1794	racemase activity, acting on amino acids and derivatives
LOCK908_RS01230	COG0656	L-ascorbic acid biosynthetic process
LOCK908_RS01235	COG1349	DNA-binding transcription factor activity
LOCK908_RS01240	COG2814	Major facilitator Superfamily
LOCK908_RS01245	COG1012	belongs to the aldehyde dehydrogenase family
LOCK908_RS01250	COG3718	enzyme involved in inositol metabolism
LOCK908_RS01255	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LOCK908_RS01260	COG3962	Belongs to the TPP enzyme family
LOCK908_RS01265	COG0673	inositol 2-dehydrogenase activity
LOCK908_RS01270	COG0673	inositol 2-dehydrogenase activity
LOCK908_RS01280	COG0191	fructose-bisphosphate aldolase activity
LOCK908_RS01285	COG1942	4-Oxalocrotonate Tautomerase
LOCK908_RS01295	COG1082	Xylose isomerase domain protein TIM barrel
LOCK908_RS01300	COG1737	Transcriptional regulator
LOCK908_RS01305	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
LOCK908_RS01315	COG2610	gluconate transmembrane transporter activity
LOCK908_RS01325	COG1121	(ABC) transporter
LOCK908_RS01340	COG2084	Dehydrogenase
LOCK908_RS01345	COG1164	Oligoendopeptidase f
LOCK908_RS01350	COG1316	TRANSCRIPTIONal
LOCK908_RS01355	COG1114	Component of the transport system for branched-chain amino acids
LOCK908_RS01370	COG1216	Glycosyl transferase, family 2
LOCK908_RS01395	COG0488	(ABC) transporter
LOCK908_RS01420	COG3118	belongs to the thioredoxin family
LOCK908_RS01455	COG0410	ABC transporter
LOCK908_RS01460	COG1694	Mazg nucleotide pyrophosphohydrolase
LOCK908_RS01475	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
LOCK908_RS01480	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
LOCK908_RS01495	COG0446	pyridine nucleotide-disulphide oxidoreductase
LOCK908_RS01500	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
LOCK908_RS01500	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
LOCK908_RS01505	COG3711	transcriptional antiterminator
LOCK908_RS01510	COG1447	Phosphotransferase system cellobiose-specific component IIA
LOCK908_RS01515	COG2723	6-phospho-beta-galactosidase activity
LOCK908_RS01535	COG2182	Extracellular solute-binding protein
LOCK908_RS01545	COG3711	transcriptional antiterminator
LOCK908_RS01545	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
LOCK908_RS01555	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
LOCK908_RS01555	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LOCK908_RS01555	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LOCK908_RS01560	COG1482	cell wall glycoprotein biosynthetic process
LOCK908_RS01565	COG2188	Transcriptional regulator
LOCK908_RS01570	COG2222	sugar isomerase
LOCK908_RS01585	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LOCK908_RS01590	COG3715	PTS system
LOCK908_RS01595	COG3716	PTS system mannose fructose sorbose family IID component
LOCK908_RS01600	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LOCK908_RS01600	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
LOCK908_RS01620	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
LOCK908_RS01625	COG0006	proline dipeptidase activity
LOCK908_RS01630	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
LOCK908_RS01635	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
LOCK908_RS01645	COG1363	Peptidase, m42
LOCK908_RS01655	COG2195	Cleaves the N-terminal amino acid of tripeptides
LOCK908_RS01660	COG4166	transmembrane transport
LOCK908_RS01700	COG1122	ATPase activity
LOCK908_RS01710	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
LOCK908_RS01730	COG0351	phosphomethylpyrimidine kinase
LOCK908_RS01735	COG0531	amino acid
LOCK908_RS01745	COG1609	Transcriptional regulator
LOCK908_RS01760	COG1172	Belongs to the binding-protein-dependent transport system permease family
LOCK908_RS01765	COG1879	ABC-type sugar transport system periplasmic component
LOCK908_RS01775	COG1598	PFAM Uncharacterised protein family UPF0150
LOCK908_RS01815	COG1131	(ABC) transporter
LOCK908_RS01860	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
LOCK908_RS01895	COG3069	C4-dicarboxylate transmembrane transporter activity
LOCK908_RS01905	COG2188	Transcriptional regulator
LOCK908_RS01920	COG1070	Carbohydrate kinase
LOCK908_RS01925	COG1028	Short-chain dehydrogenase reductase Sdr
LOCK908_RS01930	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LOCK908_RS01935	COG3775	system Galactitol-specific IIC component
LOCK908_RS01940	COG3711	transcriptional antiterminator
LOCK908_RS01945	COG0191	fructose-bisphosphate aldolase activity
LOCK908_RS01950	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LOCK908_RS01950	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LOCK908_RS01950	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
LOCK908_RS01960	COG2390	Transcriptional regulator
LOCK908_RS01970	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
LOCK908_RS01975	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LOCK908_RS01980	COG3715	PTS system
LOCK908_RS01985	COG3716	PTS system mannose fructose sorbose family IID component
LOCK908_RS01995	COG0471	metal ion transport
LOCK908_RS02000	COG0445	tRNA wobble uridine modification
LOCK908_RS02005	COG0583	DNA-binding transcription factor activity
LOCK908_RS02020	COG1122	ATPase activity
LOCK908_RS02030	COG1609	Transcriptional regulator
LOCK908_RS02035	COG2211	Major facilitator Superfamily
LOCK908_RS02045	COG1053	succinate dehydrogenase
LOCK908_RS02060	COG3775	system Galactitol-specific IIC component
LOCK908_RS02075	COG1349	DNA-binding transcription factor activity
LOCK908_RS02110	COG0561	phosphatase activity
LOCK908_RS02120	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LOCK908_RS02120	COG1263	PTS System
LOCK908_RS02125	COG1737	Transcriptional regulator
LOCK908_RS02135	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LOCK908_RS02135	COG1263	PTS System
LOCK908_RS02140	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LOCK908_RS02140	COG1263	PTS System
LOCK908_RS02140	COG2190	(PTS) system
LOCK908_RS02150	COG3711	transcriptional antiterminator
LOCK908_RS02155	COG2190	(PTS) system
LOCK908_RS02155	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LOCK908_RS02155	COG1263	PTS System
LOCK908_RS02160	COG2723	6-phospho-beta-galactosidase activity
LOCK908_RS02165	COG3711	transcriptional antiterminator
LOCK908_RS02180	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
LOCK908_RS02180	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LOCK908_RS02180	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LOCK908_RS02185	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LOCK908_RS02190	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
LOCK908_RS02190	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LOCK908_RS02190	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LOCK908_RS02210	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LOCK908_RS02210	COG1263	PTS System
LOCK908_RS02215	COG3394	polysaccharide catabolic process
LOCK908_RS02220	COG1486	melibiose metabolic process
LOCK908_RS02225	COG1737	Transcriptional regulator
LOCK908_RS02230	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LOCK908_RS02230	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
LOCK908_RS02230	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LOCK908_RS02235	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LOCK908_RS02235	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LOCK908_RS02240	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
LOCK908_RS02255	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
LOCK908_RS02270	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
LOCK908_RS02280	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
LOCK908_RS02280	COG2213	PTS system mannitol-specific
LOCK908_RS02305	COG3942	CHAP domain
LOCK908_RS02320	COG1136	(ABC) transporter
LOCK908_RS02325	COG0446	pyridine nucleotide-disulphide oxidoreductase
LOCK908_RS02330	COG0561	phosphatase activity
LOCK908_RS02340	COG1609	Transcriptional regulator
LOCK908_RS02345	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LOCK908_RS02355	COG3716	PTS system mannose fructose sorbose family IID component
LOCK908_RS02370	COG0366	Alpha amylase catalytic
LOCK908_RS02390	COG1464	Belongs to the NlpA lipoprotein family
LOCK908_RS02395	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
LOCK908_RS02415	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
LOCK908_RS02420	COG1461	Dihydroxyacetone kinase
LOCK908_RS02425	COG2376	Dihydroxyacetone kinase
LOCK908_RS02475	COG2814	Major facilitator Superfamily
LOCK908_RS02515	COG0028	Belongs to the TPP enzyme family
LOCK908_RS02530	COG4948	Mandelate Racemase Muconate Lactonizing
LOCK908_RS02535	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
LOCK908_RS02540	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
LOCK908_RS02555	COG0174	glutamine synthetase
LOCK908_RS02570	COG0789	Transcriptional regulator
LOCK908_RS02575	COG0656	L-ascorbic acid biosynthetic process
LOCK908_RS02580	COG0604	alcohol dehydrogenase
LOCK908_RS02585	COG1733	regulation of RNA biosynthetic process
LOCK908_RS02600	COG1131	(ABC) transporter
LOCK908_RS02620	COG1131	(ABC) transporter
LOCK908_RS02635	COG0308	aminopeptidase N
LOCK908_RS02640	COG0531	amino acid
LOCK908_RS02655	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
LOCK908_RS02680	COG0626	cystathionine gamma-synthase activity
LOCK908_RS02685	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LOCK908_RS02690	COG0765	amino acid transport
LOCK908_RS02700	COG1114	Component of the transport system for branched-chain amino acids
LOCK908_RS02745	COG0697	spore germination
LOCK908_RS02755	COG1131	(ABC) transporter
LOCK908_RS02770	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
LOCK908_RS02775	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
LOCK908_RS02780	COG1132	(ABC) transporter
LOCK908_RS02785	COG1132	(ABC) transporter
LOCK908_RS02795	COG2188	Transcriptional regulator
LOCK908_RS02800	COG0366	Alpha amylase catalytic
LOCK908_RS02805	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LOCK908_RS02805	COG1263	PTS System
LOCK908_RS02805	COG2190	(PTS) system
LOCK908_RS02815	COG0531	amino acid
LOCK908_RS02820	COG0039	L-malate dehydrogenase activity
LOCK908_RS02825	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
LOCK908_RS02830	COG1278	Cold shock
LOCK908_RS02845	COG0488	(ABC) transporter
LOCK908_RS02850	COG0702	epimerase
LOCK908_RS02855	COG0656	L-ascorbic acid biosynthetic process
LOCK908_RS02860	COG1113	amino acid transport
LOCK908_RS02870	COG0025	NhaP-type Na H and K H
LOCK908_RS02900	COG3338	carbonate dehydratase activity
LOCK908_RS02910	COG2816	NAD+ diphosphatase activity
LOCK908_RS02920	COG0004	ammonium transporteR
LOCK908_RS02930	COG1285	pathogenesis
LOCK908_RS02940	COG0488	(ABC) transporter
LOCK908_RS02945	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
LOCK908_RS02950	COG1573	uracil-dna glycosylase
LOCK908_RS02955	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
LOCK908_RS02960	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
LOCK908_RS02965	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
LOCK908_RS02970	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
LOCK908_RS02970	COG1215	transferase activity, transferring glycosyl groups
LOCK908_RS02975	COG3711	transcriptional antiterminator
LOCK908_RS02980	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
LOCK908_RS02980	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
LOCK908_RS02985	COG2723	6-phospho-beta-galactosidase activity
LOCK908_RS02990	COG1447	Phosphotransferase system cellobiose-specific component IIA
LOCK908_RS03000	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
LOCK908_RS03010	COG1609	Transcriptional regulator
LOCK908_RS03015	COG2017	converts alpha-aldose to the beta-anomer
LOCK908_RS03035	COG3775	system Galactitol-specific IIC component
LOCK908_RS03065	COG3684	Belongs to the aldolase LacD family
LOCK908_RS03080	COG1349	DNA-binding transcription factor activity
LOCK908_RS03090	COG0420	3'-5' exonuclease activity
LOCK908_RS03095	COG0419	ATPase involved in DNA repair
LOCK908_RS03105	COG1194	a g-specific adenine glycosylase
LOCK908_RS03115	COG2249	NAD(P)H dehydrogenase (quinone) activity
LOCK908_RS03130	COG0351	phosphomethylpyrimidine kinase
LOCK908_RS03145	COG2910	NAD(P)H-binding
LOCK908_RS03155	COG1472	Belongs to the glycosyl hydrolase 3 family
LOCK908_RS03180	COG4120	Belongs to the binding-protein-dependent transport system permease family
LOCK908_RS03190	COG0604	alcohol dehydrogenase
LOCK908_RS03200	COG0463	Glycosyl transferase, family 2
LOCK908_RS03205	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
LOCK908_RS03215	COG0745	RESPONSE REGULATOR receiver
LOCK908_RS03220	COG5002	protein histidine kinase activity
LOCK908_RS03230	COG0778	Nitroreductase
LOCK908_RS03235	COG1304	FMN binding
LOCK908_RS03285	COG0604	alcohol dehydrogenase
LOCK908_RS03300	COG0628	permease
LOCK908_RS03325	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
LOCK908_RS03335	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
LOCK908_RS03340	COG3189	MarR family transcriptional regulator
LOCK908_RS03365	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
LOCK908_RS03390	COG0105	UTP biosynthetic process
LOCK908_RS03400	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
LOCK908_RS03405	COG2267	carboxylic ester hydrolase activity
LOCK908_RS03435	COG2267	carboxylic ester hydrolase activity
LOCK908_RS03470	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
LOCK908_RS03495	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
LOCK908_RS03500	COG0343	queuine tRNA-ribosyltransferase activity
LOCK908_RS03505	COG1862	Preprotein translocase
LOCK908_RS03510	COG1012	belongs to the aldehyde dehydrogenase family
LOCK908_RS03510	COG1454	alcohol dehydrogenase
LOCK908_RS03520	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
LOCK908_RS03525	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
LOCK908_RS03530	COG4109	DRTGG domain
LOCK908_RS03535	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
LOCK908_RS03540	COG0513	Belongs to the DEAD box helicase family
LOCK908_RS03595	COG3118	belongs to the thioredoxin family
LOCK908_RS03605	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LOCK908_RS03610	COG1696	Membrane protein involved in D-alanine export
LOCK908_RS03615	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LOCK908_RS03620	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
LOCK908_RS03625	COG1719	4-vinyl reductase, 4VR
LOCK908_RS03630	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
LOCK908_RS03640	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
LOCK908_RS03655	COG0668	transmembrane transport
LOCK908_RS03670	COG1827	regulation of RNA biosynthetic process
LOCK908_RS03675	COG0006	proline dipeptidase activity
LOCK908_RS03680	COG1609	Transcriptional regulator
LOCK908_RS03685	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
LOCK908_RS03690	COG1011	Hydrolase
LOCK908_RS03730	COG0737	Belongs to the 5'-nucleotidase family
LOCK908_RS03735	COG4470	Protein conserved in bacteria
LOCK908_RS03740	COG0647	UMP catabolic process
LOCK908_RS03750	COG0586	Pfam SNARE associated Golgi protein
LOCK908_RS03755	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
LOCK908_RS03770	COG1098	S1 RNA binding domain
LOCK908_RS03920	COG0531	amino acid
LOCK908_RS03925	COG0438	transferase activity, transferring glycosyl groups
LOCK908_RS03930	COG0438	transferase activity, transferring glycosyl groups
LOCK908_RS03940	COG0436	Aminotransferase
LOCK908_RS03950	COG1368	sulfuric ester hydrolase activity
LOCK908_RS03955	COG0735	belongs to the Fur family
LOCK908_RS04000	COG0732	type I restriction modification DNA specificity domain
LOCK908_RS04010	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
LOCK908_RS04060	COG0305	Participates in initiation and elongation during chromosome replication
LOCK908_RS04270	COG0477	Major facilitator Superfamily
LOCK908_RS04290	COG0671	phosphoesterase, PA-phosphatase related
LOCK908_RS04300	COG2244	polysaccharide biosynthetic process
LOCK908_RS04305	COG1187	pseudouridine synthase activity
LOCK908_RS04315	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
LOCK908_RS04335	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
LOCK908_RS04345	COG3830	Belongs to the UPF0237 family
LOCK908_RS04370	COG2357	RelA SpoT domain protein
LOCK908_RS04380	COG0564	pseudouridine synthase activity
LOCK908_RS04390	COG3142	Participates in the control of copper homeostasis
LOCK908_RS04400	COG2706	6-phosphogluconolactonase activity
LOCK908_RS04410	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
LOCK908_RS04430	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
LOCK908_RS04440	COG1674	ftsk spoiiie
LOCK908_RS04445	COG0612	Peptidase, M16
LOCK908_RS04450	COG0612	Peptidase, M16
LOCK908_RS04455	COG1028	Short-chain dehydrogenase reductase Sdr
LOCK908_RS04460	COG1426	Protein conserved in bacteria
LOCK908_RS04465	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
LOCK908_RS04475	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
LOCK908_RS04485	COG1739	Uncharacterized protein family UPF0029
LOCK908_RS04490	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
LOCK908_RS04510	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
LOCK908_RS04515	COG2884	Cell division ATP-binding protein ftsE
LOCK908_RS04520	COG2177	Part of the ABC transporter FtsEX involved in
LOCK908_RS04530	COG0745	RESPONSE REGULATOR receiver
LOCK908_RS04535	COG5002	protein histidine kinase activity
LOCK908_RS04545	COG0573	inorganic phosphate transmembrane transporter activity
LOCK908_RS04550	COG0581	inorganic phosphate transmembrane transporter activity
LOCK908_RS04555	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
LOCK908_RS04560	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
LOCK908_RS04565	COG0704	Plays a role in the regulation of phosphate uptake
LOCK908_RS04580	COG1950	PFAM Membrane protein of
LOCK908_RS04590	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
LOCK908_RS04600	COG0492	ferredoxin-NADP+ reductase activity
LOCK908_RS04605	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
LOCK908_RS04610	COG0745	RESPONSE REGULATOR receiver
LOCK908_RS04620	COG0577	efflux transmembrane transporter activity
LOCK908_RS04620	COG1136	(ABC) transporter
LOCK908_RS04640	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
LOCK908_RS04655	COG0391	Required for morphogenesis under gluconeogenic growth conditions
LOCK908_RS04680	COG2390	Transcriptional regulator
LOCK908_RS04720	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
LOCK908_RS04730	COG0557	exoribonuclease II activity
LOCK908_RS04750	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
LOCK908_RS04780	COG0395	ABC-type sugar transport system, permease component
LOCK908_RS04785	COG1175	transmembrane transport
LOCK908_RS04805	COG0561	phosphatase activity
LOCK908_RS04815	COG0280	phosphate acetyltransferase
LOCK908_RS04820	COG0802	atpase or kinase
LOCK908_RS04825	COG4152	abc transporter atp-binding protein
LOCK908_RS04830	COG1668	transmembrane transport
LOCK908_RS04840	COG0708	Exodeoxyribonuclease III
LOCK908_RS04845	COG0812	UDP-N-acetylmuramate dehydrogenase activity
LOCK908_RS04855	COG1396	sequence-specific DNA binding
LOCK908_RS04855	COG3800	Transcriptional regulator
LOCK908_RS04865	COG1176	ABC-type spermidine putrescine transport system, permease component I
LOCK908_RS04870	COG1177	transmembrane transport
LOCK908_RS04875	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
LOCK908_RS04895	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
LOCK908_RS04900	COG1309	transcriptional regulator
LOCK908_RS04930	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
LOCK908_RS04950	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
LOCK908_RS04955	COG1459	type II secretion system
LOCK908_RS04985	COG0827	DNA restriction-modification system
LOCK908_RS04995	COG1113	amino acid transport
LOCK908_RS05095	COG4695	Portal protein
LOCK908_RS05115	COG2261	transglycosylase associated protein
LOCK908_RS05130	COG0745	RESPONSE REGULATOR receiver
LOCK908_RS05135	COG3850	Histidine kinase
LOCK908_RS05135	COG5002	protein histidine kinase activity
LOCK908_RS05165	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
LOCK908_RS05225	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
LOCK908_RS05230	COG2814	Major facilitator Superfamily
LOCK908_RS05235	COG0561	phosphatase activity
LOCK908_RS05240	COG2326	polyphosphate kinase activity
LOCK908_RS05245	COG3590	peptidase
LOCK908_RS05285	COG0673	inositol 2-dehydrogenase activity
LOCK908_RS05295	COG1447	Phosphotransferase system cellobiose-specific component IIA
LOCK908_RS05315	COG0514	ATP-dependent DNA helicase (RecQ)
LOCK908_RS05320	COG2309	aminopeptidase activity
LOCK908_RS05340	COG1295	ribonuclease BN
LOCK908_RS05345	COG0716	FMN binding
LOCK908_RS05350	COG0024	Methionine aminopeptidase
LOCK908_RS05355	COG0463	Glycosyl transferase, family 2
LOCK908_RS05375	COG1210	Utp--glucose-1-phosphate uridylyltransferase
LOCK908_RS05385	COG1442	glycosyl transferase family 8
LOCK908_RS05385	COG1216	Glycosyl transferase, family 2
LOCK908_RS05390	COG1442	glycosyl transferase family 8
LOCK908_RS05400	COG0653	protein targeting
LOCK908_RS05405	COG2723	6-phospho-beta-galactosidase activity
LOCK908_RS05410	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LOCK908_RS05410	COG2190	(PTS) system
LOCK908_RS05410	COG1263	PTS System
LOCK908_RS05415	COG4485	Bacterial membrane protein, YfhO
LOCK908_RS05430	COG0463	Glycosyl transferase, family 2
LOCK908_RS05440	COG4129	membrane
LOCK908_RS05445	COG1278	Cold shock
LOCK908_RS05460	COG1705	Flagellar rod assembly protein muramidase FlgJ
LOCK908_RS05475	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
LOCK908_RS05480	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
LOCK908_RS05505	COG1368	sulfuric ester hydrolase activity
LOCK908_RS05515	COG4975	Glucose uptake
LOCK908_RS05550	COG0590	tRNA wobble adenosine to inosine editing
LOCK908_RS05585	COG2814	Major facilitator Superfamily
LOCK908_RS05615	COG0588	phosphoglycerate mutase activity
LOCK908_RS05640	COG2514	catechol 2,3-dioxygenase activity
LOCK908_RS05645	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
LOCK908_RS05650	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
LOCK908_RS05655	COG1435	thymidine kinase activity
LOCK908_RS05665	COG2890	protein-(glutamine-N5) methyltransferase activity
LOCK908_RS05670	COG0009	L-threonylcarbamoyladenylate synthase
LOCK908_RS05685	COG0356	it plays a direct role in the translocation of protons across the membrane
LOCK908_RS05735	COG1077	Cell shape determining protein MreB Mrl
LOCK908_RS05755	COG0772	Belongs to the SEDS family
LOCK908_RS05760	COG0509	glycine decarboxylation via glycine cleavage system
LOCK908_RS05765	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
LOCK908_RS05770	COG1464	Belongs to the NlpA lipoprotein family
LOCK908_RS05785	COG2011	ABC-type metal ion transport system permease component
LOCK908_RS05795	COG0719	Fe-S assembly protein
LOCK908_RS05800	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
LOCK908_RS05805	COG0822	iron-sulfur transferase activity
LOCK908_RS05810	COG0719	Fe-S assembly protein
LOCK908_RS05845	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
LOCK908_RS05850	COG2918	glutathione biosynthetic process
LOCK908_RS05850	COG1181	Belongs to the D-alanine--D-alanine ligase family
LOCK908_RS05855	COG5506	Protein of unknown function (DUF1694)
LOCK908_RS05865	COG1760	l-serine dehydratase
LOCK908_RS05870	COG1760	l-serine dehydratase
LOCK908_RS05880	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
LOCK908_RS05885	COG1028	Short-chain dehydrogenase reductase Sdr
LOCK908_RS05895	COG1428	Deoxynucleoside kinase
LOCK908_RS05905	COG4166	transmembrane transport
LOCK908_RS05910	COG2205	protein histidine kinase activity
LOCK908_RS05915	COG0745	RESPONSE REGULATOR receiver
LOCK908_RS05965	COG1307	EDD domain protein, DegV family
LOCK908_RS05975	COG2197	response regulator
LOCK908_RS05980	COG4585	Histidine kinase
LOCK908_RS05990	COG1131	(ABC) transporter
LOCK908_RS06010	COG2183	response to ionizing radiation
LOCK908_RS06015	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
LOCK908_RS06050	COG1956	GAF domain-containing protein
LOCK908_RS06055	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
LOCK908_RS06060	COG1104	cysteine desulfurase activity
LOCK908_RS06070	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
LOCK908_RS06075	COG0525	valine-tRNA ligase activity
LOCK908_RS06090	COG2003	Belongs to the UPF0758 family
LOCK908_RS06095	COG1077	Cell shape determining protein MreB Mrl
LOCK908_RS06100	COG1792	Involved in formation and maintenance of cell shape
LOCK908_RS06110	COG0850	regulation of cytokinetic process
LOCK908_RS06115	COG2894	cell division
LOCK908_RS06120	COG0765	amino acid transport
LOCK908_RS06125	COG1126	abc transporter atp-binding protein
LOCK908_RS06130	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LOCK908_RS06145	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LOCK908_RS06155	COG2001	Belongs to the MraZ family
LOCK908_RS06170	COG0768	penicillin binding
LOCK908_RS06195	COG0849	cell division
LOCK908_RS06210	COG0762	integral membrane protein
LOCK908_RS06220	COG3599	regulation of cell shape
LOCK908_RS06230	COG1278	Cold shock
LOCK908_RS06240	COG2814	Major facilitator Superfamily
LOCK908_RS06245	COG3853	Toxic anion resistance protein (TelA)
LOCK908_RS06270	COG1104	cysteine desulfurase activity
LOCK908_RS06280	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
LOCK908_RS06300	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
LOCK908_RS06310	COG1597	lipid kinase activity
LOCK908_RS06350	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
LOCK908_RS06375	COG4476	Belongs to the UPF0223 family
LOCK908_RS06380	COG0483	inositol monophosphate 1-phosphatase activity
LOCK908_RS06385	COG1217	gtp-binding protein TYPA
LOCK908_RS06395	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
LOCK908_RS06400	COG4471	UPF0298 protein
LOCK908_RS06405	COG0742	ribosomal rna small subunit methyltransferase
LOCK908_RS06415	COG3480	Lon protease (S16) C-terminal proteolytic domain
LOCK908_RS06425	COG2333	competence protein COMEC
LOCK908_RS06425	COG0658	competence protein
LOCK908_RS06430	COG1466	dna polymerase III delta subunit
LOCK908_RS06485	COG1132	(ABC) transporter
LOCK908_RS06495	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
LOCK908_RS06510	COG0765	amino acid transport
LOCK908_RS06515	COG1126	abc transporter atp-binding protein
LOCK908_RS06525	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
LOCK908_RS06525	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LOCK908_RS06525	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LOCK908_RS06530	COG1105	Belongs to the carbohydrate kinase PfkB family
LOCK908_RS06535	COG1349	DNA-binding transcription factor activity
LOCK908_RS06545	COG2755	lipolytic protein G-D-S-L family
LOCK908_RS06545	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
LOCK908_RS06555	COG0300	oxidoreductase activity
LOCK908_RS06560	COG5416	Lipopolysaccharide assembly protein A domain
LOCK908_RS06565	COG0542	response to heat
LOCK908_RS06580	COG0737	Belongs to the 5'-nucleotidase family
LOCK908_RS06595	COG0587	DNA-directed DNA polymerase activity
LOCK908_RS06615	COG2996	Protein conserved in bacteria
LOCK908_RS06630	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
LOCK908_RS06635	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
LOCK908_RS06640	COG1187	pseudouridine synthase activity
LOCK908_RS06645	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
LOCK908_RS06660	COG0514	ATP-dependent DNA helicase (RecQ)
LOCK908_RS06675	COG0539	negative regulation of cytoplasmic translation
LOCK908_RS06700	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
LOCK908_RS06715	COG0488	(ABC) transporter
LOCK908_RS06720	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
LOCK908_RS06730	COG1272	protein, Hemolysin III
LOCK908_RS06735	COG1307	EDD domain protein, DegV family
LOCK908_RS06740	COG2755	lipolytic protein G-D-S-L family
LOCK908_RS06745	COG4698	Protein conserved in bacteria
LOCK908_RS06750	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
LOCK908_RS06760	COG3409	Peptidoglycan-binding domain 1 protein
LOCK908_RS06760	COG0793	Belongs to the peptidase S41A family
LOCK908_RS06805	COG0758	DNA mediated transformation
LOCK908_RS06810	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
LOCK908_RS06830	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
LOCK908_RS06845	COG0187	DNA topoisomerase II activity
LOCK908_RS06850	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
LOCK908_RS06860	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
LOCK908_RS06865	COG0583	DNA-binding transcription factor activity
LOCK908_RS06870	COG1227	inorganic diphosphatase activity
LOCK908_RS06875	COG4974	Belongs to the 'phage' integrase family
LOCK908_RS06880	COG0577	efflux transmembrane transporter activity
LOCK908_RS06885	COG1136	(ABC) transporter
LOCK908_RS06890	COG5002	protein histidine kinase activity
LOCK908_RS06895	COG0745	RESPONSE REGULATOR receiver
LOCK908_RS06915	COG0778	Nitroreductase
LOCK908_RS06925	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
LOCK908_RS06960	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
LOCK908_RS06975	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
LOCK908_RS06985	COG1307	EDD domain protein, DegV family
LOCK908_RS06995	COG1293	RNA-binding protein homologous to eukaryotic snRNP
LOCK908_RS07010	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
LOCK908_RS07015	COG0284	orotidine-5'-phosphate decarboxylase activity
LOCK908_RS07030	COG0505	Belongs to the CarA family
LOCK908_RS07035	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
LOCK908_RS07045	COG2233	PERMEase
LOCK908_RS07050	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
LOCK908_RS07055	COG0564	pseudouridine synthase activity
LOCK908_RS07060	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
LOCK908_RS07075	COG0328	RNA-DNA hybrid ribonuclease activity
LOCK908_RS07085	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LOCK908_RS07105	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LOCK908_RS07110	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LOCK908_RS07115	COG0583	DNA-binding transcription factor activity
LOCK908_RS07120	COG3590	peptidase
LOCK908_RS07125	COG0095	Lipoate-protein ligase
LOCK908_RS07140	COG0116	Belongs to the methyltransferase superfamily
LOCK908_RS07160	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
LOCK908_RS07165	COG2131	deaminase
LOCK908_RS07170	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
LOCK908_RS07185	COG0436	Aminotransferase
LOCK908_RS07200	COG1199	ATP-dependent helicase activity
LOCK908_RS07200	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
LOCK908_RS07215	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
LOCK908_RS07230	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
LOCK908_RS07230	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
LOCK908_RS07245	COG2151	metal-sulfur cluster biosynthetic enzyme
LOCK908_RS07250	COG1942	4-Oxalocrotonate Tautomerase
LOCK908_RS07255	COG3271	cysteine-type peptidase activity
LOCK908_RS07255	COG2274	protein secretion by the type I secretion system
LOCK908_RS07260	COG3842	ATPase activity
LOCK908_RS07265	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
LOCK908_RS07270	COG2384	SAM-dependent methyltransferase
LOCK908_RS07275	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
LOCK908_RS07280	COG0358	DNA primase activity
LOCK908_RS07315	COG1121	(ABC) transporter
LOCK908_RS07325	COG1381	Involved in DNA repair and RecF pathway recombination
LOCK908_RS07335	COG0295	cytidine deaminase activity
LOCK908_RS07350	COG1702	phosphate starvation-inducible protein PhoH
LOCK908_RS07370	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
LOCK908_RS07375	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
LOCK908_RS07380	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
LOCK908_RS07410	COG0860	N-Acetylmuramoyl-L-alanine amidase
LOCK908_RS07410	COG3103	Sh3 type 3 domain protein
LOCK908_RS07410	COG4991	sh3 domain protein
LOCK908_RS07425	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
LOCK908_RS07435	COG1385	rRNA (uridine-N3-)-methyltransferase activity
LOCK908_RS07450	COG2094	Belongs to the DNA glycosylase MPG family
LOCK908_RS07480	COG2249	NAD(P)H dehydrogenase (quinone) activity
LOCK908_RS07490	COG0673	inositol 2-dehydrogenase activity
LOCK908_RS07495	COG0438	transferase activity, transferring glycosyl groups
LOCK908_RS07545	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
LOCK908_RS07555	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
LOCK908_RS07555	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
LOCK908_RS07590	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
LOCK908_RS07600	COG0635	Involved in the biosynthesis of porphyrin-containing compound
LOCK908_RS07605	COG0196	riboflavin kinase activity
LOCK908_RS07615	COG0861	Integral membrane protein TerC family
LOCK908_RS07640	COG0195	Participates in both transcription termination and antitermination
LOCK908_RS07660	COG0750	zinc metalloprotease
LOCK908_RS07665	COG4589	Belongs to the CDS family
LOCK908_RS07670	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
LOCK908_RS07700	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
LOCK908_RS07705	COG0204	Acyl-transferase
LOCK908_RS07710	COG0531	amino acid
LOCK908_RS07720	COG1132	(ABC) transporter
LOCK908_RS07725	COG1132	(ABC) transporter
LOCK908_RS07730	COG3763	UPF0154 protein
LOCK908_RS07735	COG4224	UPF0291 protein
LOCK908_RS07755	COG1837	Belongs to the UPF0109 family
LOCK908_RS07765	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
LOCK908_RS07785	COG0552	protein localization to endoplasmic reticulum
LOCK908_RS07790	COG1196	nuclear chromosome segregation
LOCK908_RS07795	COG0571	ribonuclease III activity
LOCK908_RS07805	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LOCK908_RS07810	COG0601	transmembrane transport
LOCK908_RS07815	COG4608	Belongs to the ABC transporter superfamily
LOCK908_RS07825	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LOCK908_RS07835	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
LOCK908_RS07840	COG1461	Dihydroxyacetone kinase
LOCK908_RS07855	COG1564	THIamine pyrophosphokinase
LOCK908_RS07860	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
LOCK908_RS07865	COG1162	GTPase activity
LOCK908_RS07870	COG2815	serine threonine protein kinase
LOCK908_RS07870	COG0515	serine threonine protein kinase
LOCK908_RS07880	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
LOCK908_RS07880	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
LOCK908_RS07890	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
LOCK908_RS07895	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
LOCK908_RS07905	COG0194	GDP metabolic process
LOCK908_RS07920	COG0497	DNA recombination
LOCK908_RS07925	COG1438	arginine binding
LOCK908_RS07930	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
LOCK908_RS07940	COG1722	exodeoxyribonuclease VII activity
LOCK908_RS07960	COG1302	Protein conserved in bacteria
LOCK908_RS07965	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
LOCK908_RS07970	COG0006	proline dipeptidase activity
LOCK908_RS07975	COG0211	Belongs to the bacterial ribosomal protein bL27 family
LOCK908_RS07980	COG2868	ribosomal protein
LOCK908_RS07985	COG0261	This protein binds to 23S rRNA in the presence of protein L20
LOCK908_RS08010	COG2936	dipeptidyl-peptidase activity
LOCK908_RS08020	COG0789	Transcriptional regulator
LOCK908_RS08025	COG1982	Orn Lys Arg decarboxylase major
LOCK908_RS08030	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
LOCK908_RS08045	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
LOCK908_RS08050	COG1940	carbohydrate kinase activity
LOCK908_RS08060	COG0705	Rhomboid family
LOCK908_RS08060	COG0457	Tetratricopeptide repeat
LOCK908_RS08065	COG0768	penicillin binding
LOCK908_RS08075	COG4841	protein insertion into membrane
LOCK908_RS08080	COG2197	response regulator
LOCK908_RS08085	COG4585	Histidine kinase
LOCK908_RS08095	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
LOCK908_RS08100	COG0572	uridine kinase
LOCK908_RS08105	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
LOCK908_RS08110	COG0072	phenylalanine-tRNA ligase activity
LOCK908_RS08120	COG1733	regulation of RNA biosynthetic process
LOCK908_RS08130	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LOCK908_RS08140	COG0706	membrane insertase activity
LOCK908_RS08145	COG5002	protein histidine kinase activity
LOCK908_RS08150	COG0745	RESPONSE REGULATOR receiver
LOCK908_RS08155	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
LOCK908_RS08170	COG2226	methyltransferase
LOCK908_RS08175	COG0799	negative regulation of ribosome biogenesis
LOCK908_RS08185	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
LOCK908_RS08190	COG1534	Rna-binding protein
LOCK908_RS08195	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
LOCK908_RS08200	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
LOCK908_RS08205	COG0346	lactoylglutathione lyase activity
LOCK908_RS08215	COG0400	carboxylic ester hydrolase activity
LOCK908_RS08240	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
LOCK908_RS08245	COG0464	growth
LOCK908_RS08275	COG1484	DNA-dependent DNA replication
LOCK908_RS08290	COG0237	dephospho-CoA kinase activity
LOCK908_RS08295	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
LOCK908_RS08300	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
LOCK908_RS08300	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
LOCK908_RS08305	COG0670	Belongs to the BI1 family
LOCK908_RS08340	COG1674	ftsk spoiiie
LOCK908_RS08345	COG1674	ftsk spoiiie
LOCK908_RS08355	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LOCK908_RS08360	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LOCK908_RS08385	COG1131	(ABC) transporter
LOCK908_RS08390	COG0537	adenosine 5'-monophosphoramidase activity
LOCK908_RS08400	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
LOCK908_RS08405	COG3481	metal-dependent phosphohydrolase, HD sub domain
LOCK908_RS08415	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
LOCK908_RS08420	COG0564	pseudouridine synthase activity
LOCK908_RS08425	COG1438	arginine binding
LOCK908_RS08430	COG0018	arginyl-trna synthetase
LOCK908_RS08450	COG0167	dihydroorotate dehydrogenase activity
LOCK908_RS08465	COG1393	Belongs to the ArsC family
LOCK908_RS08470	COG1234	tRNA 3'-trailer cleavage
LOCK908_RS08485	COG1136	(ABC) transporter
LOCK908_RS08490	COG0745	RESPONSE REGULATOR receiver
LOCK908_RS08495	COG0642	Histidine kinase
LOCK908_RS08500	COG0602	queuosine metabolic process
LOCK908_RS08510	COG3682	Transcriptional regulator
LOCK908_RS08515	COG0151	Belongs to the GarS family
LOCK908_RS08525	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
LOCK908_RS08530	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
LOCK908_RS08550	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
LOCK908_RS08560	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
LOCK908_RS08575	COG2814	Major facilitator Superfamily
LOCK908_RS08585	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
LOCK908_RS08595	COG0542	response to heat
LOCK908_RS08610	COG1253	flavin adenine dinucleotide binding
LOCK908_RS08615	COG0628	permease
LOCK908_RS08620	COG2153	protein acetylation
LOCK908_RS08630	COG3557	Belongs to the UPF0374 family
LOCK908_RS08650	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
LOCK908_RS08660	COG0028	Belongs to the TPP enzyme family
LOCK908_RS08665	COG3425	synthase
LOCK908_RS08675	COG0183	Belongs to the thiolase family
LOCK908_RS08695	COG2017	converts alpha-aldose to the beta-anomer
LOCK908_RS08700	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
LOCK908_RS08720	COG3091	SprT-like family
LOCK908_RS08725	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
LOCK908_RS08730	COG4120	Belongs to the binding-protein-dependent transport system permease family
LOCK908_RS08765	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
LOCK908_RS08770	COG2188	Transcriptional regulator
LOCK908_RS08775	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
LOCK908_RS08780	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
LOCK908_RS08785	COG0823	Involved in the tonB-independent uptake of proteins
LOCK908_RS08785	COG4946	Tricorn protease homolog
LOCK908_RS08785	COG1506	peptidase
LOCK908_RS08810	COG3104	oligopeptide transport
LOCK908_RS08815	COG0577	efflux transmembrane transporter activity
LOCK908_RS08815	COG1136	(ABC) transporter
LOCK908_RS08830	COG2211	Major facilitator Superfamily
LOCK908_RS08945	COG0833	amino acid
LOCK908_RS08950	COG3527	Alpha-acetolactate decarboxylase
LOCK908_RS08955	COG0028	Belongs to the TPP enzyme family
LOCK908_RS08990	COG0564	pseudouridine synthase activity
LOCK908_RS09015	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
LOCK908_RS09065	COG0511	ligase activity, forming carbon-carbon bonds
LOCK908_RS09075	COG2851	Citrate transporter
LOCK908_RS09110	COG0778	Nitroreductase
LOCK908_RS09115	COG1131	(ABC) transporter
LOCK908_RS09125	COG1309	transcriptional regulator
LOCK908_RS09130	COG2814	Major facilitator Superfamily
LOCK908_RS09155	COG1131	(ABC) transporter
LOCK908_RS09185	COG0577	efflux transmembrane transporter activity
LOCK908_RS09185	COG1136	(ABC) transporter
LOCK908_RS09190	COG4608	Belongs to the ABC transporter superfamily
LOCK908_RS09195	COG0444	Belongs to the ABC transporter superfamily
LOCK908_RS09205	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LOCK908_RS09210	COG0601	transmembrane transport
LOCK908_RS09215	COG4166	transmembrane transport
LOCK908_RS09225	COG1132	(ABC) transporter
LOCK908_RS09230	COG1132	(ABC) transporter
LOCK908_RS09245	COG5549	protein import
LOCK908_RS09245	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LOCK908_RS09250	COG3620	sequence-specific DNA binding
LOCK908_RS09305	COG0791	NLP P60 protein
LOCK908_RS09305	COG1388	LysM domain
LOCK908_RS09305	COG3103	Sh3 type 3 domain protein
LOCK908_RS09355	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
LOCK908_RS09360	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
LOCK908_RS09365	COG1061	Type III restriction enzyme res subunit
LOCK908_RS09370	COG1002	Type II restriction enzyme, methylase subunits
LOCK908_RS09375	COG0519	Catalyzes the synthesis of GMP from XMP
LOCK908_RS09395	COG4690	dipeptidase activity
LOCK908_RS09400	COG1607	acyl-coa hydrolase
LOCK908_RS09405	COG3973	AAA domain
LOCK908_RS09415	COG0569	domain protein
LOCK908_RS09415	COG0475	glutathione-regulated potassium exporter activity
LOCK908_RS09420	COG2267	carboxylic ester hydrolase activity
LOCK908_RS09430	COG1914	H( )-stimulated, divalent metal cation uptake system
LOCK908_RS09440	COG0588	phosphoglycerate mutase activity
LOCK908_RS09445	COG0235	Class ii aldolase
LOCK908_RS09455	COG1136	(ABC) transporter
LOCK908_RS09460	COG0531	amino acid
LOCK908_RS09470	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
LOCK908_RS09475	COG0726	polysaccharide deacetylase
LOCK908_RS09490	COG0489	protein tyrosine kinase activity
LOCK908_RS09510	COG1216	Glycosyl transferase, family 2
LOCK908_RS09510	COG1442	glycosyl transferase family 8
LOCK908_RS09535	COG0463	Glycosyl transferase, family 2
LOCK908_RS09540	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
LOCK908_RS09550	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
LOCK908_RS09560	COG0463	Glycosyl transferase, family 2
LOCK908_RS09570	COG0765	amino acid transport
LOCK908_RS09575	COG0765	amino acid transport
LOCK908_RS09580	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LOCK908_RS09600	COG0735	belongs to the Fur family
LOCK908_RS09605	COG0194	GDP metabolic process
LOCK908_RS09610	COG0456	acetyltransferase
LOCK908_RS09620	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
LOCK908_RS09645	COG0058	SHG alpha-glucan phosphorylase activity
LOCK908_RS09665	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
LOCK908_RS09670	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
LOCK908_RS09680	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
LOCK908_RS09690	COG1393	Belongs to the ArsC family
LOCK908_RS09700	COG4464	protein tyrosine phosphatase activity
LOCK908_RS09705	COG1316	TRANSCRIPTIONal
LOCK908_RS09710	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
LOCK908_RS09715	COG1091	dTDP-4-dehydrorhamnose reductase activity
LOCK908_RS09720	COG1088	dTDP-glucose 4,6-dehydratase activity
LOCK908_RS09730	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
LOCK908_RS09740	COG0297	glycogen (starch) synthase activity
LOCK908_RS09775	COG0489	protein tyrosine kinase activity
LOCK908_RS09790	COG4708	membrane
LOCK908_RS09795	COG1028	Short-chain dehydrogenase reductase Sdr
LOCK908_RS09815	COG4608	Belongs to the ABC transporter superfamily
LOCK908_RS09820	COG0444	Belongs to the ABC transporter superfamily
LOCK908_RS09825	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LOCK908_RS09830	COG0601	transmembrane transport
LOCK908_RS09835	COG4166	transmembrane transport
LOCK908_RS09840	COG2814	Major facilitator Superfamily
LOCK908_RS09845	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
LOCK908_RS09850	COG1556	Lactate utilization protein
LOCK908_RS09855	COG1139	Iron-sulfur cluster binding protein
LOCK908_RS09860	COG0247	lactate metabolic process
LOCK908_RS09870	COG1447	Phosphotransferase system cellobiose-specific component IIA
LOCK908_RS09885	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
LOCK908_RS09920	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LOCK908_RS09975	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
LOCK908_RS09990	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LOCK908_RS09990	COG2190	(PTS) system
LOCK908_RS09990	COG1263	PTS System
LOCK908_RS09995	COG0366	Alpha amylase catalytic
LOCK908_RS10000	COG1609	Transcriptional regulator
LOCK908_RS10015	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
LOCK908_RS10030	COG0439	Biotin carboxylase
LOCK908_RS10045	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
LOCK908_RS10050	COG1028	Short-chain dehydrogenase reductase Sdr
LOCK908_RS10060	COG2070	2-Nitropropane dioxygenase
LOCK908_RS10070	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
LOCK908_RS10080	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
LOCK908_RS10090	COG1979	alcohol dehydrogenase
LOCK908_RS10115	COG1215	transferase activity, transferring glycosyl groups
LOCK908_RS10135	COG3706	GGDEF domain
LOCK908_RS10140	COG0446	pyridine nucleotide-disulphide oxidoreductase
LOCK908_RS10175	COG1846	Transcriptional regulator
LOCK908_RS10180	COG0494	nUDIX hydrolase
LOCK908_RS10185	COG0588	phosphoglycerate mutase activity
LOCK908_RS10205	COG0628	permease
LOCK908_RS10215	COG2246	polysaccharide biosynthetic process
LOCK908_RS10220	COG0028	Belongs to the TPP enzyme family
LOCK908_RS10265	COG0460	homoserine dehydrogenase
LOCK908_RS10270	COG0527	aspartate kinase activity
LOCK908_RS10275	COG2268	Band 7 protein
LOCK908_RS10295	COG0436	Aminotransferase
LOCK908_RS10305	COG0596	Alpha beta hydrolase
LOCK908_RS10315	COG1511	domain protein
LOCK908_RS10315	COG1511	domain protein
LOCK908_RS10325	COG0367	asparagine synthase
LOCK908_RS10345	COG0142	geranyltranstransferase activity
LOCK908_RS10355	COG4152	abc transporter atp-binding protein
LOCK908_RS10370	COG1131	(ABC) transporter
LOCK908_RS10380	COG1028	Short-chain dehydrogenase reductase Sdr
LOCK908_RS10385	COG2723	6-phospho-beta-galactosidase activity
LOCK908_RS10390	COG1263	PTS System
LOCK908_RS10390	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LOCK908_RS10390	COG2190	(PTS) system
LOCK908_RS10395	COG3711	transcriptional antiterminator
LOCK908_RS10400	COG1132	(ABC) transporter
LOCK908_RS10405	COG1132	(ABC) transporter
LOCK908_RS10420	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
LOCK908_RS10425	COG4988	ABC transporter
LOCK908_RS10430	COG1294	oxidase, subunit
LOCK908_RS10435	COG1271	oxidase subunit
LOCK908_RS10460	COG0697	spore germination
LOCK908_RS10465	COG0519	Catalyzes the synthesis of GMP from XMP
LOCK908_RS10480	COG2365	Tyrosine phosphatase family
LOCK908_RS10485	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
LOCK908_RS10495	COG1268	BioY protein
LOCK908_RS10515	COG0505	Belongs to the CarA family
LOCK908_RS10525	COG1253	flavin adenine dinucleotide binding
LOCK908_RS10540	COG2814	Major facilitator Superfamily
LOCK908_RS10565	COG0531	amino acid
LOCK908_RS10585	COG1266	CAAX protease self-immunity
LOCK908_RS10590	COG1316	TRANSCRIPTIONal
LOCK908_RS10600	COG1131	(ABC) transporter
LOCK908_RS10605	COG1725	Transcriptional regulator
LOCK908_RS10610	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
LOCK908_RS10615	COG0488	(ABC) transporter
LOCK908_RS10620	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
LOCK908_RS10635	COG1214	PFAM Peptidase M22, glycoprotease
LOCK908_RS10670	COG0470	DNA polymerase III
LOCK908_RS10675	COG3870	Protein conserved in bacteria
LOCK908_RS10700	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
LOCK908_RS10705	COG0590	tRNA wobble adenosine to inosine editing
LOCK908_RS10715	COG2813	Specifically methylates the guanine in position
LOCK908_RS10720	COG0392	lysyltransferase activity
LOCK908_RS10720	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
LOCK908_RS10735	COG1609	Transcriptional regulator
LOCK908_RS10765	COG0477	Major facilitator Superfamily
LOCK908_RS10780	COG0438	transferase activity, transferring glycosyl groups
LOCK908_RS10785	COG0438	transferase activity, transferring glycosyl groups
LOCK908_RS10790	COG1012	belongs to the aldehyde dehydrogenase family
LOCK908_RS10810	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
LOCK908_RS10820	COG2096	Adenosyltransferase
LOCK908_RS10850	COG0250	Participates in transcription elongation, termination and antitermination
LOCK908_RS10885	COG4939	FMN-binding domain protein
LOCK908_RS10950	COG1131	(ABC) transporter
LOCK908_RS10975	COG3688	RNA-binding protein containing a PIN domain
LOCK908_RS10980	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LOCK908_RS10985	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
LOCK908_RS10995	COG0277	FAD linked oxidase domain protein
LOCK908_RS11010	COG4377	Putative membrane peptidase family (DUF2324)
LOCK908_RS11020	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LOCK908_RS11040	COG1131	(ABC) transporter
LOCK908_RS11050	COG4956	integral membrane protein (PIN domain superfamily)
LOCK908_RS11055	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
LOCK908_RS11060	COG0756	dUTP diphosphatase activity
LOCK908_RS11065	COG2388	GCN5-related N-acetyl-transferase
LOCK908_RS11090	COG1131	(ABC) transporter
LOCK908_RS11100	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
LOCK908_RS11100	COG0574	Belongs to the PEP-utilizing enzyme family
LOCK908_RS11105	COG0517	IMP dehydrogenase activity
LOCK908_RS11110	COG0588	phosphoglycerate mutase activity
LOCK908_RS11135	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
LOCK908_RS11140	COG2814	Major facilitator Superfamily
LOCK908_RS11150	COG2814	Major facilitator Superfamily
LOCK908_RS11200	COG1136	(ABC) transporter
LOCK908_RS11200	COG0577	efflux transmembrane transporter activity
LOCK908_RS11205	COG1136	(ABC) transporter
LOCK908_RS11255	COG1695	Transcriptional regulator
LOCK908_RS11275	COG0667	Aldo Keto reductase
LOCK908_RS11325	COG3279	Response regulator of the LytR AlgR family
LOCK908_RS11390	COG4989	oxidoreductase activity
LOCK908_RS11395	COG4221	oxidoreductase activity
LOCK908_RS11400	COG1902	pentaerythritol trinitrate reductase activity
LOCK908_RS11410	COG0114	fumarate hydratase activity
LOCK908_RS11420	COG1914	H( )-stimulated, divalent metal cation uptake system
LOCK908_RS11425	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
LOCK908_RS11435	COG2814	Major facilitator Superfamily
LOCK908_RS11465	COG1108	ABC-type Mn2 Zn2 transport systems permease components
LOCK908_RS11470	COG1121	(ABC) transporter
LOCK908_RS11495	COG0803	Belongs to the bacterial solute-binding protein 9 family
LOCK908_RS11510	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
LOCK908_RS11545	COG1116	anion transmembrane transporter activity
LOCK908_RS11550	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
LOCK908_RS11575	COG1132	(ABC) transporter
LOCK908_RS11605	COG1136	(ABC) transporter
LOCK908_RS11615	COG0789	Transcriptional regulator
LOCK908_RS11680	COG0200	Binds to the 23S rRNA
LOCK908_RS11785	COG0450	alkyl hydroperoxide reductase
LOCK908_RS11835	COG0542	response to heat
LOCK908_RS11840	COG4463	regulation of RNA biosynthetic process
LOCK908_RS11910	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
LOCK908_RS11915	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
LOCK908_RS11935	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
LOCK908_RS11940	COG0037	tRNA processing
LOCK908_RS11945	COG1098	S1 RNA binding domain
LOCK908_RS11955	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
LOCK908_RS11960	COG2244	polysaccharide biosynthetic process
LOCK908_RS11965	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
LOCK908_RS11975	COG0039	L-malate dehydrogenase activity
LOCK908_RS11990	COG1511	domain protein
LOCK908_RS11990	COG1511	domain protein
LOCK908_RS12005	COG1376	ErfK ybiS ycfS ynhG family protein
LOCK908_RS12010	COG0493	'glutamate synthase
LOCK908_RS12015	COG0067	glutamate synthase
LOCK908_RS12015	COG0069	glutamate synthase activity
LOCK908_RS12015	COG0070	glutamate synthase
LOCK908_RS12020	COG4708	membrane
LOCK908_RS12030	COG2337	Toxic component of a toxin-antitoxin (TA) module
LOCK908_RS12055	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
LOCK908_RS12085	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
LOCK908_RS12095	COG0504	CTP synthase activity
LOCK908_RS12100	COG1252	NADH dehydrogenase
LOCK908_RS12130	COG0095	Lipoate-protein ligase
LOCK908_RS12135	COG1078	dGTPase activity
LOCK908_RS12165	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
LOCK908_RS12170	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
LOCK908_RS12180	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
LOCK908_RS12185	COG4619	ABC transporter
LOCK908_RS12190	COG0390	transport system, permease component
LOCK908_RS12200	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
LOCK908_RS12205	COG4466	Protein conserved in bacteria
LOCK908_RS12210	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
LOCK908_RS12215	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
LOCK908_RS12220	COG0084	hydrolase, TatD family'
LOCK908_RS12230	COG3684	Belongs to the aldolase LacD family
LOCK908_RS12240	COG3279	Response regulator of the LytR AlgR family
LOCK908_RS12245	COG3290	protein histidine kinase activity
LOCK908_RS12250	COG1132	(ABC) transporter
LOCK908_RS12255	COG1132	(ABC) transporter
LOCK908_RS12270	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LOCK908_RS12270	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LOCK908_RS12280	COG1801	Protein of unknown function DUF72
LOCK908_RS12300	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
LOCK908_RS12310	COG1881	PFAM PEBP family protein
LOCK908_RS12320	COG4086	secreted protein
LOCK908_RS12325	COG0248	Ppx GppA phosphatase
LOCK908_RS12330	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
LOCK908_RS12340	COG4989	oxidoreductase activity
LOCK908_RS12345	COG2226	methyltransferase
LOCK908_RS12355	COG0534	Mate efflux family protein
LOCK908_RS12360	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
LOCK908_RS12365	COG1704	LemA family
LOCK908_RS12380	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LOCK908_RS12390	COG1174	glycine betaine transport
LOCK908_RS12395	COG3973	AAA domain
LOCK908_RS12400	COG0583	DNA-binding transcription factor activity
LOCK908_RS12420	COG0640	Transcriptional regulator
LOCK908_RS12440	COG1418	mRNA catabolic process
LOCK908_RS12450	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
LOCK908_RS12455	COG0667	Aldo Keto reductase
LOCK908_RS12480	COG0588	phosphoglycerate mutase activity
LOCK908_RS12485	COG0561	phosphatase activity
LOCK908_RS12500	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LOCK908_RS12515	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
LOCK908_RS12520	COG1811	Na channel or pump
LOCK908_RS12540	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
LOCK908_RS12540	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LOCK908_RS12540	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LOCK908_RS12545	COG1105	Belongs to the carbohydrate kinase PfkB family
LOCK908_RS12555	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
LOCK908_RS12565	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
LOCK908_RS12570	COG0163	prenyltransferase activity
LOCK908_RS12595	COG0477	Major facilitator Superfamily
LOCK908_RS12610	COG3775	system Galactitol-specific IIC component
LOCK908_RS12625	COG1349	DNA-binding transcription factor activity
LOCK908_RS12640	COG0235	Class ii aldolase
LOCK908_RS12645	COG4806	L-rhamnose isomerase
LOCK908_RS12650	COG3254	rhamnose metabolic process
LOCK908_RS12655	COG1070	Carbohydrate kinase
LOCK908_RS12660	COG2814	Major facilitator Superfamily
LOCK908_RS12685	COG0366	Alpha amylase catalytic
LOCK908_RS12715	COG3716	PTS system mannose fructose sorbose family IID component
LOCK908_RS12720	COG3715	PTS system
LOCK908_RS12730	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
LOCK908_RS12740	COG1414	Transcriptional regulator
LOCK908_RS12750	COG1028	Short-chain dehydrogenase reductase Sdr
LOCK908_RS12770	COG5492	domain, Protein
LOCK908_RS12775	COG3345	alpha-galactosidase
LOCK908_RS12785	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LOCK908_RS12785	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
LOCK908_RS12790	COG3716	PTS system mannose fructose sorbose family IID component
LOCK908_RS12795	COG3715	PTS system
LOCK908_RS12810	COG1609	Transcriptional regulator
LOCK908_RS12820	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LOCK908_RS12820	COG1263	PTS System
LOCK908_RS12825	COG1132	(ABC) transporter
LOCK908_RS12840	COG2190	(PTS) system
LOCK908_RS12840	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LOCK908_RS12840	COG1263	PTS System
LOCK908_RS12860	COG3964	amidohydrolase
LOCK908_RS12905	COG3732	PTS system glucitol sorbitol-specific
LOCK908_RS12910	COG3730	PTS system glucitol sorbitol-specific
LOCK908_RS12920	COG3711	transcriptional antiterminator
LOCK908_RS12920	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
LOCK908_RS12950	COG0561	phosphatase activity
LOCK908_RS12955	COG3623	hexulose-6-phosphate isomerase
LOCK908_RS12965	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
LOCK908_RS12980	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
LOCK908_RS13005	COG1446	asparaginase
LOCK908_RS13015	COG2188	Transcriptional regulator
LOCK908_RS13035	COG1051	belongs to the nudix hydrolase family
LOCK908_RS13060	COG1335	isochorismatase
LOCK908_RS13065	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
LOCK908_RS13070	COG0584	glycerophosphoryl diester phosphodiesterase
LOCK908_RS13075	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
LOCK908_RS13085	COG0395	ABC-type sugar transport system, permease component
LOCK908_RS13095	COG3842	ATPase activity
LOCK908_RS13110	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
LOCK908_RS13120	COG1737	Transcriptional regulator
LOCK908_RS13125	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LOCK908_RS13130	COG3716	PTS system mannose fructose sorbose family IID component
LOCK908_RS13145	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
LOCK908_RS13150	COG0656	L-ascorbic acid biosynthetic process
LOCK908_RS13155	COG0789	Transcriptional regulator
LOCK908_RS13165	COG2076	Multidrug Resistance protein
LOCK908_RS13175	COG1132	(ABC) transporter
LOCK908_RS13205	COG2365	Tyrosine phosphatase family
LOCK908_RS13245	COG4166	transmembrane transport
LOCK908_RS13260	COG2211	Major facilitator Superfamily
LOCK908_RS13270	COG2217	Heavy metal translocating P-type atpase
LOCK908_RS13275	COG0071	Belongs to the small heat shock protein (HSP20) family
LOCK908_RS13285	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LOCK908_RS13290	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
LOCK908_RS13305	COG5002	protein histidine kinase activity
LOCK908_RS13310	COG0745	RESPONSE REGULATOR receiver
LOCK908_RS13320	COG0765	amino acid transport
LOCK908_RS13345	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
LOCK908_RS13350	COG2188	Transcriptional regulator
LOCK908_RS13355	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
LOCK908_RS13360	COG1447	Phosphotransferase system cellobiose-specific component IIA
LOCK908_RS13380	COG1335	isochorismatase
LOCK908_RS13385	COG2814	Major facilitator Superfamily
LOCK908_RS13390	COG2807	transmembrane transport
LOCK908_RS13395	COG0667	Aldo Keto reductase
LOCK908_RS13405	COG3716	PTS system mannose fructose sorbose family IID component
LOCK908_RS13410	COG3715	PTS system
LOCK908_RS13465	COG3409	Peptidoglycan-binding domain 1 protein
LOCK908_RS13470	COG0765	amino acid transport
LOCK908_RS13475	COG1126	abc transporter atp-binding protein
LOCK908_RS13515	COG4778	phosphonate C-P lyase system protein PhnL
LOCK908_RS13520	COG3001	Fructosamine kinase
LOCK908_RS13525	COG1126	abc transporter atp-binding protein
LOCK908_RS13530	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LOCK908_RS13535	COG0765	amino acid transport
LOCK908_RS13550	COG0714	Associated with various cellular activities
LOCK908_RS13560	COG1305	Transglutaminase-like
LOCK908_RS13565	COG0438	transferase activity, transferring glycosyl groups
LOCK908_RS13595	COG3493	citrate carrier protein
LOCK908_RS13600	COG3290	protein histidine kinase activity
LOCK908_RS13605	COG4565	transcriptional regulatory protein
LOCK908_RS13615	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LOCK908_RS13650	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
LOCK908_RS13670	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
LOCK908_RS13675	COG3711	transcriptional antiterminator
LOCK908_RS13680	COG2213	PTS system mannitol-specific
LOCK908_RS13690	COG0561	phosphatase activity
LOCK908_RS13715	COG0577	efflux transmembrane transporter activity
LOCK908_RS13715	COG1136	(ABC) transporter
LOCK908_RS13725	COG0604	alcohol dehydrogenase
LOCK908_RS13755	COG0436	Aminotransferase
LOCK908_RS13760	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
LOCK908_RS13780	COG0371	Dehydrogenase
LOCK908_RS13790	COG1473	amidohydrolase
LOCK908_RS13815	COG1132	(ABC) transporter
LOCK908_RS13835	COG0706	membrane insertase activity