locus-tag	class	description
CYG41_RS00010	COG0592	DNA-directed DNA polymerase activity
CYG41_RS00015	COG2501	S4 domain
CYG41_RS00025	COG0187	DNA topoisomerase II activity
CYG41_RS00055	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
CYG41_RS00070	COG0629	single-stranded DNA binding
CYG41_RS00085	COG0693	protein deglycase activity
CYG41_RS00090	COG1271	oxidase subunit
CYG41_RS00095	COG1294	oxidase, subunit
CYG41_RS00120	COG1266	CAAX protease self-immunity
CYG41_RS00160	COG4555	ABC transporter
CYG41_RS00165	COG0004	ammonium transporteR
CYG41_RS00185	COG0577	efflux transmembrane transporter activity
CYG41_RS00185	COG1136	(ABC) transporter
CYG41_RS00195	COG0561	phosphatase activity
CYG41_RS00215	COG0110	maltose O-acetyltransferase activity
CYG41_RS00265	COG3409	Peptidoglycan-binding domain 1 protein
CYG41_RS00280	COG3250	beta-galactosidase activity
CYG41_RS00285	COG1196	nuclear chromosome segregation
CYG41_RS00285	COG1511	domain protein
CYG41_RS00285	COG4372	Transposase
CYG41_RS00290	COG0800	Aldolase
CYG41_RS00295	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CYG41_RS00305	COG1312	Catalyzes the dehydration of D-mannonate
CYG41_RS00310	COG0246	Mannitol dehydrogenase
CYG41_RS00345	COG2814	Major facilitator Superfamily
CYG41_RS00365	COG2409	Drug exporters of the RND superfamily
CYG41_RS00365	COG1033	growth of symbiont in host cell
CYG41_RS00370	COG1309	transcriptional regulator
CYG41_RS00380	COG0402	S-adenosylhomocysteine deaminase activity
CYG41_RS00440	COG2217	Heavy metal translocating P-type atpase
CYG41_RS00450	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CYG41_RS00480	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CYG41_RS00480	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CYG41_RS00480	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CYG41_RS00485	COG0383	alpha-mannosidase activity
CYG41_RS00495	COG2723	6-phospho-beta-galactosidase activity
CYG41_RS00500	COG1940	carbohydrate kinase activity
CYG41_RS00505	COG0159	tryptophan synthase activity
CYG41_RS00560	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
CYG41_RS00585	COG0019	diaminopimelate decarboxylase activity
CYG41_RS00595	COG0527	aspartate kinase activity
CYG41_RS00605	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CYG41_RS00615	COG1396	sequence-specific DNA binding
CYG41_RS00620	COG0494	nUDIX hydrolase
CYG41_RS00645	COG0305	Participates in initiation and elongation during chromosome replication
CYG41_RS00655	COG1263	PTS System
CYG41_RS00655	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CYG41_RS00660	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
CYG41_RS00675	COG1309	transcriptional regulator
CYG41_RS00680	COG1136	(ABC) transporter
CYG41_RS00680	COG0577	efflux transmembrane transporter activity
CYG41_RS00705	COG2217	Heavy metal translocating P-type atpase
CYG41_RS00710	COG0640	Transcriptional regulator
CYG41_RS00755	COG3464	Transposase
CYG41_RS00760	COG3547	Transposase (IS116 IS110 IS902 family)
CYG41_RS00800	COG2814	Major facilitator Superfamily
CYG41_RS00815	COG5002	protein histidine kinase activity
CYG41_RS00815	COG3850	Histidine kinase
CYG41_RS00820	COG0745	RESPONSE REGULATOR receiver
CYG41_RS00825	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CYG41_RS00835	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CYG41_RS00840	COG1447	Phosphotransferase system cellobiose-specific component IIA
CYG41_RS00850	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CYG41_RS00855	COG2723	6-phospho-beta-galactosidase activity
CYG41_RS00860	COG2188	Transcriptional regulator
CYG41_RS00880	COG2252	PERMEase
CYG41_RS00900	COG1116	anion transmembrane transporter activity
CYG41_RS00905	COG4521	taurine ABC transporter
CYG41_RS00910	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CYG41_RS00915	COG0446	pyridine nucleotide-disulphide oxidoreductase
CYG41_RS00920	COG2391	methyltransferase activity
CYG41_RS00930	COG0346	lactoylglutathione lyase activity
CYG41_RS00985	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CYG41_RS01015	COG0191	fructose-bisphosphate aldolase activity
CYG41_RS01035	COG0477	Major facilitator Superfamily
CYG41_RS01040	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
CYG41_RS01045	COG4166	transmembrane transport
CYG41_RS01065	COG1131	(ABC) transporter
CYG41_RS01085	COG1132	(ABC) transporter
CYG41_RS01090	COG1396	sequence-specific DNA binding
CYG41_RS01100	COG0446	pyridine nucleotide-disulphide oxidoreductase
CYG41_RS01150	COG0716	FMN binding
CYG41_RS01165	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CYG41_RS01175	COG2261	transglycosylase associated protein
CYG41_RS01190	COG1302	Protein conserved in bacteria
CYG41_RS01245	COG3442	glutamine amidotransferase
CYG41_RS01270	COG1192	Involved in chromosome partitioning
CYG41_RS01275	COG1475	DNA binding
CYG41_RS01280	COG4481	Protein conserved in bacteria
CYG41_RS01285	COG0012	GTP binding
CYG41_RS01295	COG0517	IMP dehydrogenase activity
CYG41_RS01295	COG0516	GMP reductase activity
CYG41_RS01320	COG1686	Belongs to the peptidase S11 family
CYG41_RS01330	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CYG41_RS01345	COG0656	L-ascorbic acid biosynthetic process
CYG41_RS01350	COG1349	DNA-binding transcription factor activity
CYG41_RS01355	COG2814	Major facilitator Superfamily
CYG41_RS01365	COG1012	belongs to the aldehyde dehydrogenase family
CYG41_RS01370	COG3718	enzyme involved in inositol metabolism
CYG41_RS01375	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CYG41_RS01380	COG3962	Belongs to the TPP enzyme family
CYG41_RS01385	COG0673	inositol 2-dehydrogenase activity
CYG41_RS01390	COG0673	inositol 2-dehydrogenase activity
CYG41_RS01400	COG0191	fructose-bisphosphate aldolase activity
CYG41_RS01405	COG1942	4-Oxalocrotonate Tautomerase
CYG41_RS01415	COG1082	Xylose isomerase domain protein TIM barrel
CYG41_RS01420	COG1737	Transcriptional regulator
CYG41_RS01425	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
CYG41_RS01440	COG2610	gluconate transmembrane transporter activity
CYG41_RS01455	COG1215	transferase activity, transferring glycosyl groups
CYG41_RS01465	COG2244	polysaccharide biosynthetic process
CYG41_RS01480	COG1121	(ABC) transporter
CYG41_RS01495	COG2084	Dehydrogenase
CYG41_RS01500	COG1164	Oligoendopeptidase f
CYG41_RS01505	COG1316	TRANSCRIPTIONal
CYG41_RS01510	COG1114	Component of the transport system for branched-chain amino acids
CYG41_RS01525	COG1216	Glycosyl transferase, family 2
CYG41_RS01550	COG0488	(ABC) transporter
CYG41_RS01575	COG3118	belongs to the thioredoxin family
CYG41_RS01610	COG0410	ABC transporter
CYG41_RS01615	COG1694	Mazg nucleotide pyrophosphohydrolase
CYG41_RS01630	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
CYG41_RS01635	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
CYG41_RS01650	COG0446	pyridine nucleotide-disulphide oxidoreductase
CYG41_RS01670	COG2182	Extracellular solute-binding protein
CYG41_RS01680	COG1482	cell wall glycoprotein biosynthetic process
CYG41_RS01685	COG2188	Transcriptional regulator
CYG41_RS01690	COG2222	sugar isomerase
CYG41_RS01710	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CYG41_RS01720	COG3716	PTS system mannose fructose sorbose family IID component
CYG41_RS01725	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
CYG41_RS01725	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CYG41_RS01740	COG3775	system Galactitol-specific IIC component
CYG41_RS01755	COG3414	Phosphotransferase system galactitol-specific IIB component
CYG41_RS01780	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
CYG41_RS01785	COG0006	proline dipeptidase activity
CYG41_RS01790	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CYG41_RS01795	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CYG41_RS01805	COG1363	Peptidase, m42
CYG41_RS01815	COG2195	Cleaves the N-terminal amino acid of tripeptides
CYG41_RS01820	COG4166	transmembrane transport
CYG41_RS01840	COG1122	ATPase activity
CYG41_RS01850	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
CYG41_RS01870	COG0351	phosphomethylpyrimidine kinase
CYG41_RS01875	COG0531	amino acid
CYG41_RS01885	COG1609	Transcriptional regulator
CYG41_RS01895	COG1598	PFAM Uncharacterised protein family UPF0150
CYG41_RS02005	COG3711	transcriptional antiterminator
CYG41_RS02015	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CYG41_RS02015	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CYG41_RS02015	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CYG41_RS02020	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CYG41_RS02030	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CYG41_RS02035	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CYG41_RS02040	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CYG41_RS02070	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
CYG41_RS02075	COG1940	carbohydrate kinase activity
CYG41_RS02080	COG1349	DNA-binding transcription factor activity
CYG41_RS02085	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CYG41_RS02085	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CYG41_RS02085	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CYG41_RS02090	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CYG41_RS02095	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CYG41_RS02095	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CYG41_RS02110	COG0191	fructose-bisphosphate aldolase activity
CYG41_RS02120	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CYG41_RS02120	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
CYG41_RS02135	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CYG41_RS02140	COG1609	Transcriptional regulator
CYG41_RS02145	COG2188	Transcriptional regulator
CYG41_RS02165	COG1735	metal-dependent hydrolase with the TIM-barrel fold
CYG41_RS02170	COG0626	cystathionine gamma-synthase activity
CYG41_RS02175	COG3457	Alanine racemase
CYG41_RS02180	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
CYG41_RS02195	COG1122	ATPase activity
CYG41_RS02205	COG4948	Mandelate Racemase Muconate Lactonizing
CYG41_RS02210	COG1472	Belongs to the glycosyl hydrolase 3 family
CYG41_RS02230	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
CYG41_RS02310	COG2801	Transposase and inactivated derivatives
CYG41_RS02315	COG2801	Transposase and inactivated derivatives
CYG41_RS02335	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
CYG41_RS02380	COG2271	Major facilitator Superfamily
CYG41_RS02400	COG3250	beta-galactosidase activity
CYG41_RS02405	COG0531	amino acid
CYG41_RS02410	COG0833	amino acid
CYG41_RS02415	COG2207	Transcriptional regulator
CYG41_RS02425	COG2271	Major facilitator Superfamily
CYG41_RS02430	COG1473	amidohydrolase
CYG41_RS02440	COG1126	abc transporter atp-binding protein
CYG41_RS02445	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CYG41_RS02450	COG0765	amino acid transport
CYG41_RS02455	COG0765	amino acid transport
CYG41_RS02480	COG3942	CHAP domain
CYG41_RS02500	COG1136	(ABC) transporter
CYG41_RS02505	COG0446	pyridine nucleotide-disulphide oxidoreductase
CYG41_RS02510	COG0561	phosphatase activity
CYG41_RS02545	COG1464	Belongs to the NlpA lipoprotein family
CYG41_RS02550	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
CYG41_RS02575	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
CYG41_RS02580	COG1461	Dihydroxyacetone kinase
CYG41_RS02585	COG2376	Dihydroxyacetone kinase
CYG41_RS02595	COG1131	(ABC) transporter
CYG41_RS02665	COG2814	Major facilitator Superfamily
CYG41_RS02685	COG0028	Belongs to the TPP enzyme family
CYG41_RS02705	COG4948	Mandelate Racemase Muconate Lactonizing
CYG41_RS02710	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CYG41_RS02720	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
CYG41_RS02730	COG0174	glutamine synthetase
CYG41_RS02740	COG1113	amino acid transport
CYG41_RS02745	COG0789	Transcriptional regulator
CYG41_RS02750	COG0656	L-ascorbic acid biosynthetic process
CYG41_RS02760	COG0604	alcohol dehydrogenase
CYG41_RS02765	COG1733	regulation of RNA biosynthetic process
CYG41_RS02780	COG1131	(ABC) transporter
CYG41_RS02800	COG1131	(ABC) transporter
CYG41_RS02820	COG0308	aminopeptidase N
CYG41_RS02825	COG0531	amino acid
CYG41_RS02860	COG1028	Short-chain dehydrogenase reductase Sdr
CYG41_RS02870	COG2271	Major facilitator Superfamily
CYG41_RS02875	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CYG41_RS02880	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
CYG41_RS02905	COG0626	cystathionine gamma-synthase activity
CYG41_RS02910	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CYG41_RS02915	COG0765	amino acid transport
CYG41_RS02925	COG1114	Component of the transport system for branched-chain amino acids
CYG41_RS02995	COG0697	spore germination
CYG41_RS03000	COG3464	Transposase
CYG41_RS03010	COG1131	(ABC) transporter
CYG41_RS03035	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
CYG41_RS03040	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
CYG41_RS03050	COG1132	(ABC) transporter
CYG41_RS03055	COG1132	(ABC) transporter
CYG41_RS03065	COG2188	Transcriptional regulator
CYG41_RS03070	COG0366	Alpha amylase catalytic
CYG41_RS03075	COG2190	(PTS) system
CYG41_RS03075	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CYG41_RS03075	COG1263	PTS System
CYG41_RS03085	COG0531	amino acid
CYG41_RS03090	COG0039	L-malate dehydrogenase activity
CYG41_RS03095	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CYG41_RS03100	COG1278	Cold shock
CYG41_RS03120	COG0488	(ABC) transporter
CYG41_RS03135	COG0656	L-ascorbic acid biosynthetic process
CYG41_RS03140	COG1113	amino acid transport
CYG41_RS03150	COG0025	NhaP-type Na H and K H
CYG41_RS03180	COG3338	carbonate dehydratase activity
CYG41_RS03200	COG0745	RESPONSE REGULATOR receiver
CYG41_RS03205	COG5002	protein histidine kinase activity
CYG41_RS03210	COG1131	(ABC) transporter
CYG41_RS03225	COG0004	ammonium transporteR
CYG41_RS03235	COG1285	pathogenesis
CYG41_RS03255	COG0488	(ABC) transporter
CYG41_RS03265	COG1573	uracil-dna glycosylase
CYG41_RS03270	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
CYG41_RS03275	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
CYG41_RS03280	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CYG41_RS03305	COG3711	transcriptional antiterminator
CYG41_RS03310	COG3711	transcriptional antiterminator
CYG41_RS03315	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CYG41_RS03315	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CYG41_RS03325	COG1447	Phosphotransferase system cellobiose-specific component IIA
CYG41_RS03335	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CYG41_RS03345	COG1609	Transcriptional regulator
CYG41_RS03350	COG2017	converts alpha-aldose to the beta-anomer
CYG41_RS03360	COG3775	system Galactitol-specific IIC component
CYG41_RS03390	COG3684	Belongs to the aldolase LacD family
CYG41_RS03405	COG1349	DNA-binding transcription factor activity
CYG41_RS03420	COG0420	3'-5' exonuclease activity
CYG41_RS03425	COG0419	ATPase involved in DNA repair
CYG41_RS03445	COG1194	a g-specific adenine glycosylase
CYG41_RS03455	COG2249	NAD(P)H dehydrogenase (quinone) activity
CYG41_RS03470	COG0351	phosphomethylpyrimidine kinase
CYG41_RS03485	COG2910	NAD(P)H-binding
CYG41_RS03490	COG1472	Belongs to the glycosyl hydrolase 3 family
CYG41_RS03515	COG4120	Belongs to the binding-protein-dependent transport system permease family
CYG41_RS03520	COG1122	ATPase activity
CYG41_RS03525	COG0604	alcohol dehydrogenase
CYG41_RS03545	COG0463	Glycosyl transferase, family 2
CYG41_RS03550	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
CYG41_RS03565	COG0745	RESPONSE REGULATOR receiver
CYG41_RS03570	COG5002	protein histidine kinase activity
CYG41_RS03580	COG2508	Transcriptional regulator
CYG41_RS03585	COG1028	Short-chain dehydrogenase reductase Sdr
CYG41_RS03595	COG0778	Nitroreductase
CYG41_RS03600	COG1304	FMN binding
CYG41_RS03635	COG0604	alcohol dehydrogenase
CYG41_RS03650	COG0628	permease
CYG41_RS03680	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CYG41_RS03690	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
CYG41_RS03695	COG3189	MarR family transcriptional regulator
CYG41_RS03725	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
CYG41_RS03740	COG1132	(ABC) transporter
CYG41_RS03750	COG0105	UTP biosynthetic process
CYG41_RS03760	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
CYG41_RS03765	COG2267	carboxylic ester hydrolase activity
CYG41_RS03800	COG2267	carboxylic ester hydrolase activity
CYG41_RS03835	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
CYG41_RS03860	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
CYG41_RS03865	COG0343	queuine tRNA-ribosyltransferase activity
CYG41_RS03870	COG1862	Preprotein translocase
CYG41_RS03875	COG1012	belongs to the aldehyde dehydrogenase family
CYG41_RS03875	COG1454	alcohol dehydrogenase
CYG41_RS03885	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
CYG41_RS03890	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CYG41_RS03900	COG4109	DRTGG domain
CYG41_RS03905	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
CYG41_RS03910	COG0513	Belongs to the DEAD box helicase family
CYG41_RS03970	COG3118	belongs to the thioredoxin family
CYG41_RS03980	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CYG41_RS03985	COG1696	Membrane protein involved in D-alanine export
CYG41_RS03990	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CYG41_RS03995	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
CYG41_RS04000	COG1719	4-vinyl reductase, 4VR
CYG41_RS04005	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
CYG41_RS04015	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
CYG41_RS04030	COG0668	transmembrane transport
CYG41_RS04060	COG1827	regulation of RNA biosynthetic process
CYG41_RS04065	COG0006	proline dipeptidase activity
CYG41_RS04070	COG1609	Transcriptional regulator
CYG41_RS04075	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CYG41_RS04085	COG1011	Hydrolase
CYG41_RS04125	COG0737	Belongs to the 5'-nucleotidase family
CYG41_RS04130	COG4470	Protein conserved in bacteria
CYG41_RS04135	COG0647	UMP catabolic process
CYG41_RS04145	COG0586	Pfam SNARE associated Golgi protein
CYG41_RS04150	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
CYG41_RS04165	COG1098	S1 RNA binding domain
CYG41_RS04315	COG0531	amino acid
CYG41_RS04320	COG0438	transferase activity, transferring glycosyl groups
CYG41_RS04325	COG0438	transferase activity, transferring glycosyl groups
CYG41_RS04335	COG0436	Aminotransferase
CYG41_RS04345	COG1368	sulfuric ester hydrolase activity
CYG41_RS04350	COG0735	belongs to the Fur family
CYG41_RS04395	COG0477	Major facilitator Superfamily
CYG41_RS04405	COG2814	Major facilitator Superfamily
CYG41_RS04415	COG0671	phosphoesterase, PA-phosphatase related
CYG41_RS04430	COG2244	polysaccharide biosynthetic process
CYG41_RS04435	COG1187	pseudouridine synthase activity
CYG41_RS04445	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
CYG41_RS04465	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
CYG41_RS04475	COG3830	Belongs to the UPF0237 family
CYG41_RS04510	COG2357	RelA SpoT domain protein
CYG41_RS04520	COG0564	pseudouridine synthase activity
CYG41_RS04530	COG3142	Participates in the control of copper homeostasis
CYG41_RS04540	COG2706	6-phosphogluconolactonase activity
CYG41_RS04550	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
CYG41_RS04575	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
CYG41_RS04595	COG1674	ftsk spoiiie
CYG41_RS04600	COG0612	Peptidase, M16
CYG41_RS04605	COG0612	Peptidase, M16
CYG41_RS04610	COG1028	Short-chain dehydrogenase reductase Sdr
CYG41_RS04615	COG1426	Protein conserved in bacteria
CYG41_RS04620	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CYG41_RS04630	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
CYG41_RS04645	COG1739	Uncharacterized protein family UPF0029
CYG41_RS04650	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
CYG41_RS04685	COG2884	Cell division ATP-binding protein ftsE
CYG41_RS04690	COG2177	Part of the ABC transporter FtsEX involved in
CYG41_RS04700	COG0745	RESPONSE REGULATOR receiver
CYG41_RS04705	COG5002	protein histidine kinase activity
CYG41_RS04715	COG0573	inorganic phosphate transmembrane transporter activity
CYG41_RS04720	COG0581	inorganic phosphate transmembrane transporter activity
CYG41_RS04725	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CYG41_RS04730	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CYG41_RS04735	COG0704	Plays a role in the regulation of phosphate uptake
CYG41_RS04740	COG2801	Transposase and inactivated derivatives
CYG41_RS04760	COG1950	PFAM Membrane protein of
CYG41_RS04770	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
CYG41_RS04780	COG0492	ferredoxin-NADP+ reductase activity
CYG41_RS04785	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CYG41_RS04800	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CYG41_RS04830	COG0391	Required for morphogenesis under gluconeogenic growth conditions
CYG41_RS04840	COG1846	Transcriptional regulator
CYG41_RS04855	COG2390	Transcriptional regulator
CYG41_RS04900	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CYG41_RS04910	COG0557	exoribonuclease II activity
CYG41_RS04930	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CYG41_RS04950	COG3464	Transposase
CYG41_RS04960	COG0395	ABC-type sugar transport system, permease component
CYG41_RS04965	COG1175	transmembrane transport
CYG41_RS04970	COG3842	ATPase activity
CYG41_RS04985	COG0561	phosphatase activity
CYG41_RS04995	COG0280	phosphate acetyltransferase
CYG41_RS05000	COG0802	atpase or kinase
CYG41_RS05005	COG4152	abc transporter atp-binding protein
CYG41_RS05010	COG1668	transmembrane transport
CYG41_RS05020	COG0708	Exodeoxyribonuclease III
CYG41_RS05025	COG3464	Transposase
CYG41_RS05030	COG0812	UDP-N-acetylmuramate dehydrogenase activity
CYG41_RS05040	COG3800	Transcriptional regulator
CYG41_RS05040	COG1396	sequence-specific DNA binding
CYG41_RS05050	COG1176	ABC-type spermidine putrescine transport system, permease component I
CYG41_RS05055	COG1177	transmembrane transport
CYG41_RS05060	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
CYG41_RS05080	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
CYG41_RS05085	COG1309	transcriptional regulator
CYG41_RS05120	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CYG41_RS05140	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CYG41_RS05145	COG1459	type II secretion system
CYG41_RS05180	COG0827	DNA restriction-modification system
CYG41_RS05190	COG1113	amino acid transport
CYG41_RS05230	COG0745	RESPONSE REGULATOR receiver
CYG41_RS05235	COG3850	Histidine kinase
CYG41_RS05235	COG5002	protein histidine kinase activity
CYG41_RS05265	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CYG41_RS05335	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CYG41_RS05355	COG2814	Major facilitator Superfamily
CYG41_RS05360	COG0561	phosphatase activity
CYG41_RS05365	COG2326	polyphosphate kinase activity
CYG41_RS05370	COG3590	peptidase
CYG41_RS05425	COG0673	inositol 2-dehydrogenase activity
CYG41_RS05435	COG1447	Phosphotransferase system cellobiose-specific component IIA
CYG41_RS05460	COG0514	ATP-dependent DNA helicase (RecQ)
CYG41_RS05470	COG2309	aminopeptidase activity
CYG41_RS05490	COG1295	ribonuclease BN
CYG41_RS05495	COG0716	FMN binding
CYG41_RS05505	COG0024	Methionine aminopeptidase
CYG41_RS05510	COG0463	Glycosyl transferase, family 2
CYG41_RS05535	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CYG41_RS05545	COG2723	6-phospho-beta-galactosidase activity
CYG41_RS05550	COG1263	PTS System
CYG41_RS05550	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CYG41_RS05550	COG2190	(PTS) system
CYG41_RS05555	COG4485	Bacterial membrane protein, YfhO
CYG41_RS05570	COG0463	Glycosyl transferase, family 2
CYG41_RS05580	COG4129	membrane
CYG41_RS05585	COG1278	Cold shock
CYG41_RS05600	COG1705	Flagellar rod assembly protein muramidase FlgJ
CYG41_RS05615	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
CYG41_RS05620	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CYG41_RS05635	COG1368	sulfuric ester hydrolase activity
CYG41_RS05650	COG4975	Glucose uptake
CYG41_RS05660	COG0582	viral genome integration into host DNA
CYG41_RS05705	COG1396	sequence-specific DNA binding
CYG41_RS05785	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
CYG41_RS05960	COG3942	CHAP domain
CYG41_RS05990	COG0590	tRNA wobble adenosine to inosine editing
CYG41_RS06060	COG0588	phosphoglycerate mutase activity
CYG41_RS06085	COG2514	catechol 2,3-dioxygenase activity
CYG41_RS06090	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CYG41_RS06095	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
CYG41_RS06100	COG1435	thymidine kinase activity
CYG41_RS06115	COG2890	protein-(glutamine-N5) methyltransferase activity
CYG41_RS06120	COG0009	L-threonylcarbamoyladenylate synthase
CYG41_RS06140	COG0356	it plays a direct role in the translocation of protons across the membrane
CYG41_RS06210	COG1077	Cell shape determining protein MreB Mrl
CYG41_RS06230	COG0772	Belongs to the SEDS family
CYG41_RS06235	COG0509	glycine decarboxylation via glycine cleavage system
CYG41_RS06240	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CYG41_RS06245	COG1464	Belongs to the NlpA lipoprotein family
CYG41_RS06270	COG2011	ABC-type metal ion transport system permease component
CYG41_RS06280	COG0719	Fe-S assembly protein
CYG41_RS06285	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CYG41_RS06290	COG0822	iron-sulfur transferase activity
CYG41_RS06295	COG0719	Fe-S assembly protein
CYG41_RS06335	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CYG41_RS06345	COG2918	glutathione biosynthetic process
CYG41_RS06345	COG1181	Belongs to the D-alanine--D-alanine ligase family
CYG41_RS06360	COG1760	l-serine dehydratase
CYG41_RS06365	COG1760	l-serine dehydratase
CYG41_RS06375	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CYG41_RS06380	COG4221	oxidoreductase activity
CYG41_RS06390	COG1428	Deoxynucleoside kinase
CYG41_RS06400	COG4166	transmembrane transport
CYG41_RS06405	COG2205	protein histidine kinase activity
CYG41_RS06410	COG0745	RESPONSE REGULATOR receiver
CYG41_RS06455	COG1307	EDD domain protein, DegV family
CYG41_RS06465	COG2197	response regulator
CYG41_RS06470	COG4585	Histidine kinase
CYG41_RS06480	COG1131	(ABC) transporter
CYG41_RS06520	COG2183	response to ionizing radiation
CYG41_RS06530	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
CYG41_RS06540	COG3620	sequence-specific DNA binding
CYG41_RS06545	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
CYG41_RS06545	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CYG41_RS06555	COG1956	GAF domain-containing protein
CYG41_RS06560	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
CYG41_RS06570	COG1104	cysteine desulfurase activity
CYG41_RS06580	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
CYG41_RS06585	COG0525	valine-tRNA ligase activity
CYG41_RS06600	COG2003	Belongs to the UPF0758 family
CYG41_RS06605	COG1077	Cell shape determining protein MreB Mrl
CYG41_RS06610	COG1792	Involved in formation and maintenance of cell shape
CYG41_RS06620	COG0850	regulation of cytokinetic process
CYG41_RS06625	COG2894	cell division
CYG41_RS06630	COG0765	amino acid transport
CYG41_RS06635	COG1126	abc transporter atp-binding protein
CYG41_RS06640	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CYG41_RS06650	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CYG41_RS06675	COG2001	Belongs to the MraZ family
CYG41_RS06690	COG0768	penicillin binding
CYG41_RS06715	COG0849	cell division
CYG41_RS06730	COG0762	integral membrane protein
CYG41_RS06740	COG3599	regulation of cell shape
CYG41_RS06750	COG1278	Cold shock
CYG41_RS06760	COG2814	Major facilitator Superfamily
CYG41_RS06765	COG3853	Toxic anion resistance protein (TelA)
CYG41_RS06790	COG1104	cysteine desulfurase activity
CYG41_RS06805	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CYG41_RS06825	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CYG41_RS06835	COG1597	lipid kinase activity
CYG41_RS06900	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
CYG41_RS06925	COG4476	Belongs to the UPF0223 family
CYG41_RS06930	COG0483	inositol monophosphate 1-phosphatase activity
CYG41_RS06935	COG1217	gtp-binding protein TYPA
CYG41_RS06945	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
CYG41_RS06950	COG4471	UPF0298 protein
CYG41_RS06955	COG0742	ribosomal rna small subunit methyltransferase
CYG41_RS06965	COG3480	Lon protease (S16) C-terminal proteolytic domain
CYG41_RS06975	COG2333	competence protein COMEC
CYG41_RS06975	COG0658	competence protein
CYG41_RS06980	COG1466	dna polymerase III delta subunit
CYG41_RS07040	COG1132	(ABC) transporter
CYG41_RS07050	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
CYG41_RS07070	COG0765	amino acid transport
CYG41_RS07075	COG1126	abc transporter atp-binding protein
CYG41_RS07085	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CYG41_RS07085	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CYG41_RS07085	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CYG41_RS07090	COG1105	Belongs to the carbohydrate kinase PfkB family
CYG41_RS07095	COG1349	DNA-binding transcription factor activity
CYG41_RS07105	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
CYG41_RS07105	COG2755	lipolytic protein G-D-S-L family
CYG41_RS07115	COG0300	oxidoreductase activity
CYG41_RS07120	COG5416	Lipopolysaccharide assembly protein A domain
CYG41_RS07125	COG0542	response to heat
CYG41_RS07140	COG0737	Belongs to the 5'-nucleotidase family
CYG41_RS07155	COG0587	DNA-directed DNA polymerase activity
CYG41_RS07175	COG2996	Protein conserved in bacteria
CYG41_RS07190	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
CYG41_RS07195	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
CYG41_RS07200	COG1187	pseudouridine synthase activity
CYG41_RS07205	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
CYG41_RS07220	COG0514	ATP-dependent DNA helicase (RecQ)
CYG41_RS07235	COG0539	negative regulation of cytoplasmic translation
CYG41_RS07255	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CYG41_RS07270	COG0488	(ABC) transporter
CYG41_RS07275	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
CYG41_RS07285	COG1272	protein, Hemolysin III
CYG41_RS07290	COG1307	EDD domain protein, DegV family
CYG41_RS07295	COG2755	lipolytic protein G-D-S-L family
CYG41_RS07300	COG4698	Protein conserved in bacteria
CYG41_RS07305	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CYG41_RS07315	COG3409	Peptidoglycan-binding domain 1 protein
CYG41_RS07315	COG0793	Belongs to the peptidase S41A family
CYG41_RS07345	COG0758	DNA mediated transformation
CYG41_RS07350	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CYG41_RS07375	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
CYG41_RS07390	COG0187	DNA topoisomerase II activity
CYG41_RS07395	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CYG41_RS07405	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
CYG41_RS07410	COG0583	DNA-binding transcription factor activity
CYG41_RS07415	COG1227	inorganic diphosphatase activity
CYG41_RS07420	COG4974	Belongs to the 'phage' integrase family
CYG41_RS07425	COG0577	efflux transmembrane transporter activity
CYG41_RS07430	COG1136	(ABC) transporter
CYG41_RS07435	COG5002	protein histidine kinase activity
CYG41_RS07440	COG0745	RESPONSE REGULATOR receiver
CYG41_RS07460	COG0778	Nitroreductase
CYG41_RS07470	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CYG41_RS07510	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
CYG41_RS07525	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CYG41_RS07535	COG1307	EDD domain protein, DegV family
CYG41_RS07550	COG1293	RNA-binding protein homologous to eukaryotic snRNP
CYG41_RS07565	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
CYG41_RS07570	COG0284	orotidine-5'-phosphate decarboxylase activity
CYG41_RS07585	COG0505	Belongs to the CarA family
CYG41_RS07590	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
CYG41_RS07600	COG2233	PERMEase
CYG41_RS07605	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
CYG41_RS07615	COG0564	pseudouridine synthase activity
CYG41_RS07620	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
CYG41_RS07640	COG0328	RNA-DNA hybrid ribonuclease activity
CYG41_RS07650	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CYG41_RS07670	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CYG41_RS07675	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CYG41_RS07680	COG0583	DNA-binding transcription factor activity
CYG41_RS07690	COG3590	peptidase
CYG41_RS07695	COG0095	Lipoate-protein ligase
CYG41_RS07710	COG0116	Belongs to the methyltransferase superfamily
CYG41_RS07740	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CYG41_RS07745	COG2131	deaminase
CYG41_RS07750	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CYG41_RS07765	COG0436	Aminotransferase
CYG41_RS07780	COG1199	ATP-dependent helicase activity
CYG41_RS07780	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CYG41_RS07795	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
CYG41_RS07810	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CYG41_RS07810	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
CYG41_RS07830	COG2151	metal-sulfur cluster biosynthetic enzyme
CYG41_RS07835	COG1942	4-Oxalocrotonate Tautomerase
CYG41_RS07845	COG2274	protein secretion by the type I secretion system
CYG41_RS07845	COG3271	cysteine-type peptidase activity
CYG41_RS07855	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
CYG41_RS07860	COG2384	SAM-dependent methyltransferase
CYG41_RS07865	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CYG41_RS07870	COG0358	DNA primase activity
CYG41_RS07940	COG3953	SLT domain
CYG41_RS07940	COG5280	Phage tail tape measure protein TP901
CYG41_RS08015	COG1215	transferase activity, transferring glycosyl groups
CYG41_RS08085	COG1381	Involved in DNA repair and RecF pathway recombination
CYG41_RS08095	COG0295	cytidine deaminase activity
CYG41_RS08110	COG1702	phosphate starvation-inducible protein PhoH
CYG41_RS08130	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
CYG41_RS08135	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CYG41_RS08140	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CYG41_RS08175	COG0860	N-Acetylmuramoyl-L-alanine amidase
CYG41_RS08175	COG4991	sh3 domain protein
CYG41_RS08175	COG3103	Sh3 type 3 domain protein
CYG41_RS08190	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CYG41_RS08205	COG1385	rRNA (uridine-N3-)-methyltransferase activity
CYG41_RS08220	COG2094	Belongs to the DNA glycosylase MPG family
CYG41_RS08250	COG2249	NAD(P)H dehydrogenase (quinone) activity
CYG41_RS08280	COG0438	transferase activity, transferring glycosyl groups
CYG41_RS08330	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CYG41_RS08340	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
CYG41_RS08340	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
CYG41_RS08380	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
CYG41_RS08390	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CYG41_RS08395	COG0196	riboflavin kinase activity
CYG41_RS08405	COG0861	Integral membrane protein TerC family
CYG41_RS08430	COG0195	Participates in both transcription termination and antitermination
CYG41_RS08450	COG0750	zinc metalloprotease
CYG41_RS08455	COG4589	Belongs to the CDS family
CYG41_RS08460	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CYG41_RS08470	COG2801	Transposase and inactivated derivatives
CYG41_RS08505	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
CYG41_RS08510	COG0204	Acyl-transferase
CYG41_RS08515	COG0531	amino acid
CYG41_RS08525	COG1132	(ABC) transporter
CYG41_RS08530	COG1132	(ABC) transporter
CYG41_RS08535	COG3763	UPF0154 protein
CYG41_RS08540	COG4224	UPF0291 protein
CYG41_RS08565	COG1837	Belongs to the UPF0109 family
CYG41_RS08575	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CYG41_RS08600	COG0552	protein localization to endoplasmic reticulum
CYG41_RS08605	COG1196	nuclear chromosome segregation
CYG41_RS08610	COG0571	ribonuclease III activity
CYG41_RS08620	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CYG41_RS08625	COG0601	transmembrane transport
CYG41_RS08630	COG4608	Belongs to the ABC transporter superfamily
CYG41_RS08640	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CYG41_RS08650	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CYG41_RS08655	COG1461	Dihydroxyacetone kinase
CYG41_RS08670	COG1564	THIamine pyrophosphokinase
CYG41_RS08675	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CYG41_RS08680	COG1162	GTPase activity
CYG41_RS08685	COG0515	serine threonine protein kinase
CYG41_RS08685	COG2815	serine threonine protein kinase
CYG41_RS08695	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CYG41_RS08695	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CYG41_RS08705	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CYG41_RS08710	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CYG41_RS08720	COG0194	GDP metabolic process
CYG41_RS08735	COG0497	DNA recombination
CYG41_RS08740	COG1438	arginine binding
CYG41_RS08745	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
CYG41_RS08755	COG1722	exodeoxyribonuclease VII activity
CYG41_RS08775	COG1302	Protein conserved in bacteria
CYG41_RS08780	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
CYG41_RS08785	COG0006	proline dipeptidase activity
CYG41_RS08790	COG0211	Belongs to the bacterial ribosomal protein bL27 family
CYG41_RS08795	COG2868	ribosomal protein
CYG41_RS08800	COG0261	This protein binds to 23S rRNA in the presence of protein L20
CYG41_RS08830	COG2936	dipeptidyl-peptidase activity
CYG41_RS08840	COG0789	Transcriptional regulator
CYG41_RS08845	COG1982	Orn Lys Arg decarboxylase major
CYG41_RS08850	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
CYG41_RS08865	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CYG41_RS08870	COG1940	carbohydrate kinase activity
CYG41_RS08880	COG0457	Tetratricopeptide repeat
CYG41_RS08880	COG0705	Rhomboid family
CYG41_RS08885	COG0768	penicillin binding
CYG41_RS08890	COG3464	Transposase
CYG41_RS08900	COG4841	protein insertion into membrane
CYG41_RS08905	COG2197	response regulator
CYG41_RS08910	COG4585	Histidine kinase
CYG41_RS08920	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CYG41_RS08925	COG0572	uridine kinase
CYG41_RS08930	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CYG41_RS08940	COG0072	phenylalanine-tRNA ligase activity
CYG41_RS08950	COG1733	regulation of RNA biosynthetic process
CYG41_RS08960	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CYG41_RS08970	COG0706	membrane insertase activity
CYG41_RS08975	COG5002	protein histidine kinase activity
CYG41_RS08980	COG0745	RESPONSE REGULATOR receiver
CYG41_RS08985	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
CYG41_RS08990	COG1196	nuclear chromosome segregation
CYG41_RS08990	COG0741	lytic transglycosylase activity
CYG41_RS08990	COG0739	heme binding
CYG41_RS09015	COG2226	methyltransferase
CYG41_RS09020	COG0799	negative regulation of ribosome biogenesis
CYG41_RS09030	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
CYG41_RS09035	COG1534	Rna-binding protein
CYG41_RS09040	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
CYG41_RS09045	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
CYG41_RS09050	COG0346	lactoylglutathione lyase activity
CYG41_RS09060	COG0400	carboxylic ester hydrolase activity
CYG41_RS09085	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
CYG41_RS09130	COG1484	DNA-dependent DNA replication
CYG41_RS09145	COG0237	dephospho-CoA kinase activity
CYG41_RS09150	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
CYG41_RS09155	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CYG41_RS09155	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CYG41_RS09165	COG0670	Belongs to the BI1 family
CYG41_RS09200	COG1674	ftsk spoiiie
CYG41_RS09210	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CYG41_RS09215	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CYG41_RS09240	COG4473	ABC transporter
CYG41_RS09245	COG1131	(ABC) transporter
CYG41_RS09250	COG0537	adenosine 5'-monophosphoramidase activity
CYG41_RS09260	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CYG41_RS09265	COG3481	metal-dependent phosphohydrolase, HD sub domain
CYG41_RS09275	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CYG41_RS09280	COG0564	pseudouridine synthase activity
CYG41_RS09285	COG1438	arginine binding
CYG41_RS09290	COG0018	arginyl-trna synthetase
CYG41_RS09310	COG0167	dihydroorotate dehydrogenase activity
CYG41_RS09325	COG1393	Belongs to the ArsC family
CYG41_RS09330	COG1234	tRNA 3'-trailer cleavage
CYG41_RS09345	COG1136	(ABC) transporter
CYG41_RS09360	COG0745	RESPONSE REGULATOR receiver
CYG41_RS09365	COG0642	Histidine kinase
CYG41_RS09370	COG0602	queuosine metabolic process
CYG41_RS09380	COG3682	Transcriptional regulator
CYG41_RS09385	COG0151	Belongs to the GarS family
CYG41_RS09400	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
CYG41_RS09405	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
CYG41_RS09425	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CYG41_RS09435	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
CYG41_RS09460	COG2814	Major facilitator Superfamily
CYG41_RS09480	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CYG41_RS09490	COG0542	response to heat
CYG41_RS09505	COG1253	flavin adenine dinucleotide binding
CYG41_RS09510	COG0628	permease
CYG41_RS09515	COG2153	protein acetylation
CYG41_RS09525	COG3557	Belongs to the UPF0374 family
CYG41_RS09545	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CYG41_RS09555	COG0028	Belongs to the TPP enzyme family
CYG41_RS09565	COG3425	synthase
CYG41_RS09575	COG0183	Belongs to the thiolase family
CYG41_RS09610	COG2017	converts alpha-aldose to the beta-anomer
CYG41_RS09615	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CYG41_RS09640	COG3091	SprT-like family
CYG41_RS09645	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
CYG41_RS09650	COG4120	Belongs to the binding-protein-dependent transport system permease family
CYG41_RS09690	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
CYG41_RS09700	COG2188	Transcriptional regulator
CYG41_RS09705	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
CYG41_RS09710	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CYG41_RS09715	COG4946	Tricorn protease homolog
CYG41_RS09715	COG0823	Involved in the tonB-independent uptake of proteins
CYG41_RS09715	COG1506	peptidase
CYG41_RS09740	COG3104	oligopeptide transport
CYG41_RS09745	COG0577	efflux transmembrane transporter activity
CYG41_RS09745	COG1136	(ABC) transporter
CYG41_RS09760	COG2211	Major facilitator Superfamily
CYG41_RS09800	COG2755	lipolytic protein G-D-S-L family
CYG41_RS09800	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
CYG41_RS09885	COG0833	amino acid
CYG41_RS09895	COG3527	Alpha-acetolactate decarboxylase
CYG41_RS09900	COG0028	Belongs to the TPP enzyme family
CYG41_RS09945	COG3177	Filamentation induced by cAMP protein fic
CYG41_RS09950	COG0564	pseudouridine synthase activity
CYG41_RS09970	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
CYG41_RS10025	COG0511	ligase activity, forming carbon-carbon bonds
CYG41_RS10035	COG2851	Citrate transporter
CYG41_RS10070	COG0778	Nitroreductase
CYG41_RS10075	COG1131	(ABC) transporter
CYG41_RS10085	COG1309	transcriptional regulator
CYG41_RS10090	COG2814	Major facilitator Superfamily
CYG41_RS10120	COG1131	(ABC) transporter
CYG41_RS10130	COG4608	Belongs to the ABC transporter superfamily
CYG41_RS10135	COG0444	Belongs to the ABC transporter superfamily
CYG41_RS10145	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CYG41_RS10150	COG0601	transmembrane transport
CYG41_RS10155	COG4166	transmembrane transport
CYG41_RS10170	COG1132	(ABC) transporter
CYG41_RS10175	COG1121	(ABC) transporter
CYG41_RS10195	COG5549	protein import
CYG41_RS10195	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CYG41_RS10280	COG0519	Catalyzes the synthesis of GMP from XMP
CYG41_RS10300	COG4690	dipeptidase activity
CYG41_RS10305	COG1607	acyl-coa hydrolase
CYG41_RS10310	COG3973	AAA domain
CYG41_RS10330	COG0569	domain protein
CYG41_RS10330	COG0475	glutathione-regulated potassium exporter activity
CYG41_RS10335	COG2267	carboxylic ester hydrolase activity
CYG41_RS10345	COG1914	H( )-stimulated, divalent metal cation uptake system
CYG41_RS10355	COG0588	phosphoglycerate mutase activity
CYG41_RS10360	COG0235	Class ii aldolase
CYG41_RS10370	COG1136	(ABC) transporter
CYG41_RS10375	COG0531	amino acid
CYG41_RS10385	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CYG41_RS10390	COG0726	polysaccharide deacetylase
CYG41_RS10415	COG1091	dTDP-4-dehydrorhamnose reductase activity
CYG41_RS10420	COG1088	dTDP-glucose 4,6-dehydratase activity
CYG41_RS10430	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
CYG41_RS10455	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CYG41_RS10470	COG0765	amino acid transport
CYG41_RS10475	COG0765	amino acid transport
CYG41_RS10480	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CYG41_RS10500	COG0735	belongs to the Fur family
CYG41_RS10510	COG0194	GDP metabolic process
CYG41_RS10515	COG0456	acetyltransferase
CYG41_RS10525	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CYG41_RS10550	COG0058	SHG alpha-glucan phosphorylase activity
CYG41_RS10560	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
CYG41_RS10570	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
CYG41_RS10575	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CYG41_RS10585	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CYG41_RS10600	COG1393	Belongs to the ArsC family
CYG41_RS10615	COG4464	protein tyrosine phosphatase activity
CYG41_RS10620	COG1316	TRANSCRIPTIONal
CYG41_RS10625	COG1088	dTDP-glucose 4,6-dehydratase activity
CYG41_RS10665	COG0463	Glycosyl transferase, family 2
CYG41_RS10680	COG2244	polysaccharide biosynthetic process
CYG41_RS10685	COG0562	UDP-galactopyranose mutase
CYG41_RS10695	COG0489	protein tyrosine kinase activity
CYG41_RS10720	COG4708	membrane
CYG41_RS10725	COG1028	Short-chain dehydrogenase reductase Sdr
CYG41_RS10745	COG4608	Belongs to the ABC transporter superfamily
CYG41_RS10750	COG0444	Belongs to the ABC transporter superfamily
CYG41_RS10755	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CYG41_RS10760	COG0601	transmembrane transport
CYG41_RS10765	COG4166	transmembrane transport
CYG41_RS10770	COG2814	Major facilitator Superfamily
CYG41_RS10775	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
CYG41_RS10780	COG1556	Lactate utilization protein
CYG41_RS10785	COG1139	Iron-sulfur cluster binding protein
CYG41_RS10790	COG0247	lactate metabolic process
CYG41_RS10805	COG1447	Phosphotransferase system cellobiose-specific component IIA
CYG41_RS10820	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CYG41_RS10860	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CYG41_RS10955	COG0366	Alpha amylase catalytic
CYG41_RS10960	COG1609	Transcriptional regulator
CYG41_RS10975	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CYG41_RS10995	COG0439	Biotin carboxylase
CYG41_RS11005	COG0511	ligase activity, forming carbon-carbon bonds
CYG41_RS11010	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CYG41_RS11015	COG1028	Short-chain dehydrogenase reductase Sdr
CYG41_RS11025	COG2070	2-Nitropropane dioxygenase
CYG41_RS11035	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CYG41_RS11045	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CYG41_RS11060	COG1979	alcohol dehydrogenase
CYG41_RS11100	COG1846	Transcriptional regulator
CYG41_RS11105	COG0494	nUDIX hydrolase
CYG41_RS11110	COG0588	phosphoglycerate mutase activity
CYG41_RS11130	COG0628	permease
CYG41_RS11140	COG2246	polysaccharide biosynthetic process
CYG41_RS11145	COG0028	Belongs to the TPP enzyme family
CYG41_RS11200	COG0460	homoserine dehydrogenase
CYG41_RS11205	COG0527	aspartate kinase activity
CYG41_RS11210	COG2268	Band 7 protein
CYG41_RS11240	COG0436	Aminotransferase
CYG41_RS11260	COG0596	Alpha beta hydrolase
CYG41_RS11270	COG1511	domain protein
CYG41_RS11270	COG1511	domain protein
CYG41_RS11290	COG0367	asparagine synthase
CYG41_RS11325	COG0142	geranyltranstransferase activity
CYG41_RS11335	COG4152	abc transporter atp-binding protein
CYG41_RS11350	COG1131	(ABC) transporter
CYG41_RS11360	COG1028	Short-chain dehydrogenase reductase Sdr
CYG41_RS11370	COG1263	PTS System
CYG41_RS11370	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CYG41_RS11370	COG2190	(PTS) system
CYG41_RS11380	COG3711	transcriptional antiterminator
CYG41_RS11385	COG1132	(ABC) transporter
CYG41_RS11390	COG1132	(ABC) transporter
CYG41_RS11420	COG1518	maintenance of DNA repeat elements
CYG41_RS11425	COG3513	CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
CYG41_RS11430	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
CYG41_RS11435	COG4988	ABC transporter
CYG41_RS11440	COG1294	oxidase, subunit
CYG41_RS11445	COG1271	oxidase subunit
CYG41_RS11475	COG0697	spore germination
CYG41_RS11480	COG0519	Catalyzes the synthesis of GMP from XMP
CYG41_RS11505	COG2365	Tyrosine phosphatase family
CYG41_RS11510	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
CYG41_RS11520	COG1268	BioY protein
CYG41_RS11550	COG1253	flavin adenine dinucleotide binding
CYG41_RS11565	COG2814	Major facilitator Superfamily
CYG41_RS11595	COG0531	amino acid
CYG41_RS11615	COG1266	CAAX protease self-immunity
CYG41_RS11620	COG1316	TRANSCRIPTIONal
CYG41_RS11635	COG1131	(ABC) transporter
CYG41_RS11640	COG1725	Transcriptional regulator
CYG41_RS11645	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
CYG41_RS11650	COG0488	(ABC) transporter
CYG41_RS11655	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CYG41_RS11665	COG1214	PFAM Peptidase M22, glycoprotease
CYG41_RS11665	COG0456	acetyltransferase
CYG41_RS11670	COG1214	PFAM Peptidase M22, glycoprotease
CYG41_RS11715	COG0470	DNA polymerase III
CYG41_RS11720	COG3870	Protein conserved in bacteria
CYG41_RS11745	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CYG41_RS11755	COG0590	tRNA wobble adenosine to inosine editing
CYG41_RS11765	COG2813	Specifically methylates the guanine in position
CYG41_RS11770	COG0392	lysyltransferase activity
CYG41_RS11770	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
CYG41_RS11790	COG1609	Transcriptional regulator
CYG41_RS11835	COG0477	Major facilitator Superfamily
CYG41_RS11850	COG0438	transferase activity, transferring glycosyl groups
CYG41_RS11855	COG0438	transferase activity, transferring glycosyl groups
CYG41_RS11860	COG1012	belongs to the aldehyde dehydrogenase family
CYG41_RS11880	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
CYG41_RS11890	COG2096	Adenosyltransferase
CYG41_RS11920	COG0250	Participates in transcription elongation, termination and antitermination
CYG41_RS11970	COG4939	FMN-binding domain protein
CYG41_RS12025	COG1131	(ABC) transporter
CYG41_RS12050	COG3688	RNA-binding protein containing a PIN domain
CYG41_RS12055	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CYG41_RS12060	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
CYG41_RS12070	COG1396	sequence-specific DNA binding
CYG41_RS12100	COG4377	Putative membrane peptidase family (DUF2324)
CYG41_RS12110	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CYG41_RS12130	COG4956	integral membrane protein (PIN domain superfamily)
CYG41_RS12135	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
CYG41_RS12140	COG0756	dUTP diphosphatase activity
CYG41_RS12155	COG2388	GCN5-related N-acetyl-transferase
CYG41_RS12185	COG1131	(ABC) transporter
CYG41_RS12195	COG0574	Belongs to the PEP-utilizing enzyme family
CYG41_RS12195	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CYG41_RS12200	COG0517	IMP dehydrogenase activity
CYG41_RS12205	COG0588	phosphoglycerate mutase activity
CYG41_RS12220	COG1304	FMN binding
CYG41_RS12320	COG1695	Transcriptional regulator
CYG41_RS12340	COG0667	Aldo Keto reductase
CYG41_RS12365	COG2274	protein secretion by the type I secretion system
CYG41_RS12380	COG3279	Response regulator of the LytR AlgR family
CYG41_RS12465	COG4989	oxidoreductase activity
CYG41_RS12475	COG4221	oxidoreductase activity
CYG41_RS12480	COG1902	pentaerythritol trinitrate reductase activity
CYG41_RS12490	COG0114	fumarate hydratase activity
CYG41_RS12515	COG1914	H( )-stimulated, divalent metal cation uptake system
CYG41_RS12520	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
CYG41_RS12530	COG2814	Major facilitator Superfamily
CYG41_RS12560	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CYG41_RS12565	COG1121	(ABC) transporter
CYG41_RS12595	COG0803	Belongs to the bacterial solute-binding protein 9 family
CYG41_RS12620	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CYG41_RS12660	COG1116	anion transmembrane transporter activity
CYG41_RS12665	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CYG41_RS12700	COG2801	Transposase and inactivated derivatives
CYG41_RS12730	COG1136	(ABC) transporter
CYG41_RS12750	COG0789	Transcriptional regulator
CYG41_RS12820	COG0200	Binds to the 23S rRNA
CYG41_RS12930	COG0450	alkyl hydroperoxide reductase
CYG41_RS12980	COG0542	response to heat
CYG41_RS12985	COG4463	regulation of RNA biosynthetic process
CYG41_RS13055	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
CYG41_RS13060	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CYG41_RS13085	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
CYG41_RS13090	COG0037	tRNA processing
CYG41_RS13095	COG1098	S1 RNA binding domain
CYG41_RS13105	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
CYG41_RS13110	COG2244	polysaccharide biosynthetic process
CYG41_RS13115	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CYG41_RS13125	COG0039	L-malate dehydrogenase activity
CYG41_RS13140	COG1511	domain protein
CYG41_RS13140	COG1511	domain protein
CYG41_RS13155	COG1376	ErfK ybiS ycfS ynhG family protein
CYG41_RS13160	COG0493	'glutamate synthase
CYG41_RS13165	COG0069	glutamate synthase activity
CYG41_RS13165	COG0067	glutamate synthase
CYG41_RS13165	COG0070	glutamate synthase
CYG41_RS13170	COG4708	membrane
CYG41_RS13185	COG2337	Toxic component of a toxin-antitoxin (TA) module
CYG41_RS13210	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
CYG41_RS13240	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CYG41_RS13250	COG0504	CTP synthase activity
CYG41_RS13255	COG1252	NADH dehydrogenase
CYG41_RS13290	COG0095	Lipoate-protein ligase
CYG41_RS13295	COG1078	dGTPase activity
CYG41_RS13325	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CYG41_RS13330	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
CYG41_RS13350	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CYG41_RS13355	COG4619	ABC transporter
CYG41_RS13360	COG0390	transport system, permease component
CYG41_RS13370	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
CYG41_RS13375	COG4466	Protein conserved in bacteria
CYG41_RS13390	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
CYG41_RS13395	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
CYG41_RS13400	COG0084	hydrolase, TatD family'
CYG41_RS13410	COG3684	Belongs to the aldolase LacD family
CYG41_RS13430	COG3279	Response regulator of the LytR AlgR family
CYG41_RS13435	COG3290	protein histidine kinase activity
CYG41_RS13440	COG1132	(ABC) transporter
CYG41_RS13445	COG1132	(ABC) transporter
CYG41_RS13460	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CYG41_RS13460	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CYG41_RS13490	COG1801	Protein of unknown function DUF72
CYG41_RS13510	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
CYG41_RS13525	COG1881	PFAM PEBP family protein
CYG41_RS13535	COG4086	secreted protein
CYG41_RS13540	COG0248	Ppx GppA phosphatase
CYG41_RS13545	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
CYG41_RS13555	COG4989	oxidoreductase activity
CYG41_RS13560	COG2226	methyltransferase
CYG41_RS13570	COG0534	Mate efflux family protein
CYG41_RS13580	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
CYG41_RS13585	COG1704	LemA family
CYG41_RS13610	COG1131	(ABC) transporter
CYG41_RS13620	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CYG41_RS13630	COG1174	glycine betaine transport
CYG41_RS13645	COG3973	AAA domain
CYG41_RS13650	COG0583	DNA-binding transcription factor activity
CYG41_RS13680	COG0640	Transcriptional regulator
CYG41_RS13700	COG1418	mRNA catabolic process
CYG41_RS13710	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CYG41_RS13715	COG0667	Aldo Keto reductase
CYG41_RS13740	COG0588	phosphoglycerate mutase activity
CYG41_RS13745	COG0561	phosphatase activity
CYG41_RS13760	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CYG41_RS13780	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
CYG41_RS13785	COG1811	Na channel or pump
CYG41_RS13800	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CYG41_RS13800	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CYG41_RS13800	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CYG41_RS13805	COG1105	Belongs to the carbohydrate kinase PfkB family
CYG41_RS13815	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CYG41_RS13835	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
CYG41_RS13835	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CYG41_RS13840	COG3715	PTS system
CYG41_RS13845	COG3716	PTS system mannose fructose sorbose family IID component
CYG41_RS13850	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
CYG41_RS13855	COG0163	prenyltransferase activity
CYG41_RS13880	COG0477	Major facilitator Superfamily
CYG41_RS13890	COG4948	Mandelate Racemase Muconate Lactonizing
CYG41_RS13895	COG3775	system Galactitol-specific IIC component
CYG41_RS13900	COG3414	Phosphotransferase system galactitol-specific IIB component
CYG41_RS13905	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CYG41_RS13910	COG0800	Aldolase
CYG41_RS13920	COG1447	Phosphotransferase system cellobiose-specific component IIA
CYG41_RS13930	COG2723	6-phospho-beta-galactosidase activity
CYG41_RS13960	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CYG41_RS13965	COG2188	Transcriptional regulator
CYG41_RS13985	COG2814	Major facilitator Superfamily
CYG41_RS13990	COG1070	Carbohydrate kinase
CYG41_RS14000	COG0235	Class ii aldolase
CYG41_RS14005	COG4806	L-rhamnose isomerase
CYG41_RS14010	COG3254	rhamnose metabolic process
CYG41_RS14015	COG1070	Carbohydrate kinase
CYG41_RS14020	COG2814	Major facilitator Superfamily
CYG41_RS14045	COG0366	Alpha amylase catalytic
CYG41_RS14050	COG2801	Transposase and inactivated derivatives
CYG41_RS14075	COG1263	PTS System
CYG41_RS14075	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CYG41_RS14090	COG2190	(PTS) system
CYG41_RS14090	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CYG41_RS14090	COG1263	PTS System
CYG41_RS14110	COG3964	amidohydrolase
CYG41_RS14155	COG3732	PTS system glucitol sorbitol-specific
CYG41_RS14160	COG3730	PTS system glucitol sorbitol-specific
CYG41_RS14170	COG3711	transcriptional antiterminator
CYG41_RS14170	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CYG41_RS14185	COG0561	phosphatase activity
CYG41_RS14190	COG3623	hexulose-6-phosphate isomerase
CYG41_RS14205	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
CYG41_RS14225	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CYG41_RS14250	COG1446	asparaginase
CYG41_RS14255	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CYG41_RS14260	COG2188	Transcriptional regulator
CYG41_RS14280	COG1070	Carbohydrate kinase
CYG41_RS14285	COG1063	alcohol dehydrogenase
CYG41_RS14290	COG3716	PTS system mannose fructose sorbose family IID component
CYG41_RS14300	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CYG41_RS14300	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
CYG41_RS14330	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CYG41_RS14335	COG3775	system Galactitol-specific IIC component
CYG41_RS14350	COG0191	fructose-bisphosphate aldolase activity
CYG41_RS14355	COG2188	Transcriptional regulator
CYG41_RS14365	COG1051	belongs to the nudix hydrolase family
CYG41_RS14390	COG1335	isochorismatase
CYG41_RS14395	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
CYG41_RS14400	COG0584	glycerophosphoryl diester phosphodiesterase
CYG41_RS14405	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CYG41_RS14415	COG0395	ABC-type sugar transport system, permease component
CYG41_RS14425	COG3842	ATPase activity
CYG41_RS14440	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CYG41_RS14450	COG1737	Transcriptional regulator
CYG41_RS14455	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CYG41_RS14460	COG3716	PTS system mannose fructose sorbose family IID component
CYG41_RS14480	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
CYG41_RS14485	COG0656	L-ascorbic acid biosynthetic process
CYG41_RS14490	COG0789	Transcriptional regulator
CYG41_RS14505	COG2076	Multidrug Resistance protein
CYG41_RS14535	COG2365	Tyrosine phosphatase family
CYG41_RS14575	COG4166	transmembrane transport
CYG41_RS14590	COG2217	Heavy metal translocating P-type atpase
CYG41_RS14595	COG0071	Belongs to the small heat shock protein (HSP20) family
CYG41_RS14610	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CYG41_RS14620	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
CYG41_RS14635	COG5002	protein histidine kinase activity
CYG41_RS14640	COG0745	RESPONSE REGULATOR receiver
CYG41_RS14650	COG0765	amino acid transport
CYG41_RS14675	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CYG41_RS14680	COG2188	Transcriptional regulator
CYG41_RS14685	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CYG41_RS14690	COG1447	Phosphotransferase system cellobiose-specific component IIA
CYG41_RS14720	COG1335	isochorismatase
CYG41_RS14725	COG2814	Major facilitator Superfamily
CYG41_RS14730	COG2807	transmembrane transport
CYG41_RS14735	COG0667	Aldo Keto reductase
CYG41_RS14750	COG3716	PTS system mannose fructose sorbose family IID component
CYG41_RS14755	COG3715	PTS system
CYG41_RS14810	COG3409	Peptidoglycan-binding domain 1 protein
CYG41_RS14820	COG0765	amino acid transport
CYG41_RS14825	COG1126	abc transporter atp-binding protein
CYG41_RS14875	COG4778	phosphonate C-P lyase system protein PhnL
CYG41_RS14880	COG3001	Fructosamine kinase
CYG41_RS14885	COG1126	abc transporter atp-binding protein
CYG41_RS14890	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CYG41_RS14895	COG0765	amino acid transport
CYG41_RS14915	COG0714	Associated with various cellular activities
CYG41_RS14925	COG1305	Transglutaminase-like
CYG41_RS14930	COG0438	transferase activity, transferring glycosyl groups
CYG41_RS14940	COG2801	Transposase and inactivated derivatives
CYG41_RS14975	COG3493	citrate carrier protein
CYG41_RS14980	COG3290	protein histidine kinase activity
CYG41_RS14985	COG4565	transcriptional regulatory protein
CYG41_RS15095	COG4695	Portal protein
CYG41_RS15120	COG2261	transglycosylase associated protein
CYG41_RS15130	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CYG41_RS15150	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
CYG41_RS15155	COG3711	transcriptional antiterminator
CYG41_RS15160	COG2213	PTS system mannitol-specific
CYG41_RS15170	COG0561	phosphatase activity
CYG41_RS15195	COG1136	(ABC) transporter
CYG41_RS15195	COG0577	efflux transmembrane transporter activity
CYG41_RS15215	COG0436	Aminotransferase
CYG41_RS15220	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CYG41_RS15240	COG0371	Dehydrogenase
CYG41_RS15255	COG1473	amidohydrolase
CYG41_RS15280	COG1132	(ABC) transporter
CYG41_RS15305	COG0706	membrane insertase activity