locus-tag	class	description
GFB59_RS00010	COG0592	DNA-directed DNA polymerase activity
GFB59_RS00015	COG2501	S4 domain
GFB59_RS00025	COG0187	DNA topoisomerase II activity
GFB59_RS00050	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
GFB59_RS00065	COG0629	single-stranded DNA binding
GFB59_RS00075	COG0693	protein deglycase activity
GFB59_RS00080	COG1271	oxidase subunit
GFB59_RS00085	COG1294	oxidase, subunit
GFB59_RS00100	COG1266	CAAX protease self-immunity
GFB59_RS00125	COG4555	ABC transporter
GFB59_RS00130	COG0004	ammonium transporteR
GFB59_RS00150	COG1136	(ABC) transporter
GFB59_RS00150	COG0577	efflux transmembrane transporter activity
GFB59_RS00160	COG0561	phosphatase activity
GFB59_RS00180	COG0110	maltose O-acetyltransferase activity
GFB59_RS00220	COG3409	Peptidoglycan-binding domain 1 protein
GFB59_RS00235	COG3250	beta-galactosidase activity
GFB59_RS00250	COG2801	Transposase and inactivated derivatives
GFB59_RS00255	COG0800	Aldolase
GFB59_RS00260	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GFB59_RS00270	COG1312	Catalyzes the dehydration of D-mannonate
GFB59_RS00275	COG0246	Mannitol dehydrogenase
GFB59_RS00310	COG2814	Major facilitator Superfamily
GFB59_RS00330	COG2409	Drug exporters of the RND superfamily
GFB59_RS00330	COG1033	growth of symbiont in host cell
GFB59_RS00335	COG1309	transcriptional regulator
GFB59_RS00345	COG0402	S-adenosylhomocysteine deaminase activity
GFB59_RS00400	COG2217	Heavy metal translocating P-type atpase
GFB59_RS00410	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GFB59_RS00430	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GFB59_RS00430	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GFB59_RS00430	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GFB59_RS00435	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GFB59_RS00435	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GFB59_RS00435	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GFB59_RS00440	COG0383	alpha-mannosidase activity
GFB59_RS00450	COG2723	6-phospho-beta-galactosidase activity
GFB59_RS00455	COG1940	carbohydrate kinase activity
GFB59_RS00520	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
GFB59_RS00540	COG0019	diaminopimelate decarboxylase activity
GFB59_RS00545	COG0527	aspartate kinase activity
GFB59_RS00555	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
GFB59_RS00565	COG1396	sequence-specific DNA binding
GFB59_RS00570	COG0494	nUDIX hydrolase
GFB59_RS00590	COG0305	Participates in initiation and elongation during chromosome replication
GFB59_RS00600	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GFB59_RS00600	COG1263	PTS System
GFB59_RS00605	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
GFB59_RS00620	COG1309	transcriptional regulator
GFB59_RS00625	COG1136	(ABC) transporter
GFB59_RS00625	COG0577	efflux transmembrane transporter activity
GFB59_RS00645	COG2217	Heavy metal translocating P-type atpase
GFB59_RS00650	COG0640	Transcriptional regulator
GFB59_RS00660	COG3620	sequence-specific DNA binding
GFB59_RS00725	COG2814	Major facilitator Superfamily
GFB59_RS00735	COG5002	protein histidine kinase activity
GFB59_RS00735	COG3850	Histidine kinase
GFB59_RS00740	COG0745	RESPONSE REGULATOR receiver
GFB59_RS00745	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
GFB59_RS00755	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GFB59_RS00760	COG1447	Phosphotransferase system cellobiose-specific component IIA
GFB59_RS00770	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GFB59_RS00775	COG2723	6-phospho-beta-galactosidase activity
GFB59_RS00780	COG2188	Transcriptional regulator
GFB59_RS00800	COG2252	PERMEase
GFB59_RS00820	COG1116	anion transmembrane transporter activity
GFB59_RS00825	COG4521	taurine ABC transporter
GFB59_RS00830	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GFB59_RS00835	COG0446	pyridine nucleotide-disulphide oxidoreductase
GFB59_RS00840	COG2391	methyltransferase activity
GFB59_RS00850	COG0346	lactoylglutathione lyase activity
GFB59_RS00970	COG1126	abc transporter atp-binding protein
GFB59_RS00975	COG0765	amino acid transport
GFB59_RS00980	COG0765	amino acid transport
GFB59_RS00985	COG0778	Nitroreductase
GFB59_RS01105	COG3764	Sortase (surface protein transpeptidase)
GFB59_RS01120	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GFB59_RS01120	COG3711	transcriptional antiterminator
GFB59_RS01125	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GFB59_RS01125	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GFB59_RS01125	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GFB59_RS01130	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GFB59_RS01130	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GFB59_RS01130	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GFB59_RS01135	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GFB59_RS01140	COG0383	alpha-mannosidase activity
GFB59_RS01175	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
GFB59_RS01240	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
GFB59_RS01255	COG1472	Belongs to the glycosyl hydrolase 3 family
GFB59_RS01270	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
GFB59_RS01285	COG1070	Carbohydrate kinase
GFB59_RS01290	COG0191	fructose-bisphosphate aldolase activity
GFB59_RS01310	COG0477	Major facilitator Superfamily
GFB59_RS01325	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
GFB59_RS01330	COG4166	transmembrane transport
GFB59_RS01350	COG1131	(ABC) transporter
GFB59_RS01370	COG1132	(ABC) transporter
GFB59_RS01375	COG1396	sequence-specific DNA binding
GFB59_RS01385	COG0446	pyridine nucleotide-disulphide oxidoreductase
GFB59_RS01430	COG0716	FMN binding
GFB59_RS01445	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GFB59_RS01455	COG2261	transglycosylase associated protein
GFB59_RS01470	COG1302	Protein conserved in bacteria
GFB59_RS01510	COG3442	glutamine amidotransferase
GFB59_RS01535	COG1192	Involved in chromosome partitioning
GFB59_RS01540	COG1475	DNA binding
GFB59_RS01545	COG4481	Protein conserved in bacteria
GFB59_RS01550	COG0012	GTP binding
GFB59_RS01560	COG0517	IMP dehydrogenase activity
GFB59_RS01560	COG0516	GMP reductase activity
GFB59_RS01580	COG1686	Belongs to the peptidase S11 family
GFB59_RS01590	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
GFB59_RS01605	COG0656	L-ascorbic acid biosynthetic process
GFB59_RS01610	COG1349	DNA-binding transcription factor activity
GFB59_RS01615	COG2814	Major facilitator Superfamily
GFB59_RS01620	COG1012	belongs to the aldehyde dehydrogenase family
GFB59_RS01625	COG3718	enzyme involved in inositol metabolism
GFB59_RS01630	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GFB59_RS01635	COG3962	Belongs to the TPP enzyme family
GFB59_RS01640	COG0673	inositol 2-dehydrogenase activity
GFB59_RS01645	COG0673	inositol 2-dehydrogenase activity
GFB59_RS01655	COG0191	fructose-bisphosphate aldolase activity
GFB59_RS01660	COG1942	4-Oxalocrotonate Tautomerase
GFB59_RS01670	COG1082	Xylose isomerase domain protein TIM barrel
GFB59_RS01675	COG1737	Transcriptional regulator
GFB59_RS01680	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
GFB59_RS01690	COG2610	gluconate transmembrane transporter activity
GFB59_RS01705	COG1215	transferase activity, transferring glycosyl groups
GFB59_RS01715	COG2244	polysaccharide biosynthetic process
GFB59_RS01730	COG1121	(ABC) transporter
GFB59_RS01745	COG2084	Dehydrogenase
GFB59_RS01750	COG1164	Oligoendopeptidase f
GFB59_RS01755	COG1316	TRANSCRIPTIONal
GFB59_RS01760	COG1114	Component of the transport system for branched-chain amino acids
GFB59_RS01775	COG1216	Glycosyl transferase, family 2
GFB59_RS01800	COG0488	(ABC) transporter
GFB59_RS01825	COG3118	belongs to the thioredoxin family
GFB59_RS01860	COG0410	ABC transporter
GFB59_RS01865	COG1694	Mazg nucleotide pyrophosphohydrolase
GFB59_RS01890	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
GFB59_RS01895	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
GFB59_RS01910	COG0446	pyridine nucleotide-disulphide oxidoreductase
GFB59_RS01930	COG2182	Extracellular solute-binding protein
GFB59_RS01940	COG1482	cell wall glycoprotein biosynthetic process
GFB59_RS01945	COG2188	Transcriptional regulator
GFB59_RS01950	COG2222	sugar isomerase
GFB59_RS01965	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GFB59_RS01970	COG3715	PTS system
GFB59_RS01975	COG3716	PTS system mannose fructose sorbose family IID component
GFB59_RS01980	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
GFB59_RS01980	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GFB59_RS01995	COG3775	system Galactitol-specific IIC component
GFB59_RS02005	COG3414	Phosphotransferase system galactitol-specific IIB component
GFB59_RS02030	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
GFB59_RS02035	COG0006	proline dipeptidase activity
GFB59_RS02040	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GFB59_RS02045	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GFB59_RS02055	COG1363	Peptidase, m42
GFB59_RS02065	COG2195	Cleaves the N-terminal amino acid of tripeptides
GFB59_RS02070	COG4166	transmembrane transport
GFB59_RS02095	COG4172	Belongs to the ABC transporter superfamily
GFB59_RS02105	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
GFB59_RS02125	COG0351	phosphomethylpyrimidine kinase
GFB59_RS02130	COG0531	amino acid
GFB59_RS02135	COG1609	Transcriptional regulator
GFB59_RS02150	COG1172	Belongs to the binding-protein-dependent transport system permease family
GFB59_RS02155	COG1879	ABC-type sugar transport system periplasmic component
GFB59_RS02165	COG1598	PFAM Uncharacterised protein family UPF0150
GFB59_RS02180	COG1131	(ABC) transporter
GFB59_RS02225	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GFB59_RS02260	COG3069	C4-dicarboxylate transmembrane transporter activity
GFB59_RS02270	COG2188	Transcriptional regulator
GFB59_RS02285	COG1070	Carbohydrate kinase
GFB59_RS02290	COG1028	Short-chain dehydrogenase reductase Sdr
GFB59_RS02295	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GFB59_RS02300	COG3775	system Galactitol-specific IIC component
GFB59_RS02305	COG3711	transcriptional antiterminator
GFB59_RS02310	COG0191	fructose-bisphosphate aldolase activity
GFB59_RS02315	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GFB59_RS02315	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GFB59_RS02315	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GFB59_RS02325	COG2390	Transcriptional regulator
GFB59_RS02335	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
GFB59_RS02340	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GFB59_RS02345	COG3715	PTS system
GFB59_RS02350	COG3716	PTS system mannose fructose sorbose family IID component
GFB59_RS02370	COG1122	ATPase activity
GFB59_RS02380	COG1609	Transcriptional regulator
GFB59_RS02385	COG2211	Major facilitator Superfamily
GFB59_RS02390	COG0366	Alpha amylase catalytic
GFB59_RS02395	COG1053	succinate dehydrogenase
GFB59_RS02410	COG3775	system Galactitol-specific IIC component
GFB59_RS02425	COG1349	DNA-binding transcription factor activity
GFB59_RS02460	COG0561	phosphatase activity
GFB59_RS02470	COG1263	PTS System
GFB59_RS02470	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GFB59_RS02475	COG1737	Transcriptional regulator
GFB59_RS02485	COG1263	PTS System
GFB59_RS02485	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GFB59_RS02490	COG1263	PTS System
GFB59_RS02490	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GFB59_RS02490	COG2190	(PTS) system
GFB59_RS02500	COG3711	transcriptional antiterminator
GFB59_RS02515	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GFB59_RS02515	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GFB59_RS02515	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GFB59_RS02520	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GFB59_RS02545	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GFB59_RS02545	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GFB59_RS02545	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GFB59_RS02550	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GFB59_RS02550	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GFB59_RS02555	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
GFB59_RS02575	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GFB59_RS02590	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GFB59_RS02600	COG2213	PTS system mannitol-specific
GFB59_RS02600	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
GFB59_RS02630	COG3942	CHAP domain
GFB59_RS02645	COG1136	(ABC) transporter
GFB59_RS02650	COG0446	pyridine nucleotide-disulphide oxidoreductase
GFB59_RS02655	COG0561	phosphatase activity
GFB59_RS02695	COG1464	Belongs to the NlpA lipoprotein family
GFB59_RS02700	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
GFB59_RS02720	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
GFB59_RS02725	COG1461	Dihydroxyacetone kinase
GFB59_RS02730	COG2376	Dihydroxyacetone kinase
GFB59_RS02740	COG1131	(ABC) transporter
GFB59_RS02780	COG2814	Major facilitator Superfamily
GFB59_RS02800	COG0028	Belongs to the TPP enzyme family
GFB59_RS02815	COG4948	Mandelate Racemase Muconate Lactonizing
GFB59_RS02820	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
GFB59_RS02830	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
GFB59_RS02840	COG0174	glutamine synthetase
GFB59_RS02850	COG1113	amino acid transport
GFB59_RS02855	COG0789	Transcriptional regulator
GFB59_RS02860	COG0656	L-ascorbic acid biosynthetic process
GFB59_RS02865	COG0604	alcohol dehydrogenase
GFB59_RS02870	COG1733	regulation of RNA biosynthetic process
GFB59_RS02885	COG1131	(ABC) transporter
GFB59_RS02905	COG1131	(ABC) transporter
GFB59_RS02920	COG0308	aminopeptidase N
GFB59_RS02925	COG0531	amino acid
GFB59_RS02940	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
GFB59_RS02965	COG0626	cystathionine gamma-synthase activity
GFB59_RS02970	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GFB59_RS02975	COG0765	amino acid transport
GFB59_RS02985	COG1114	Component of the transport system for branched-chain amino acids
GFB59_RS03010	COG0697	spore germination
GFB59_RS03020	COG1131	(ABC) transporter
GFB59_RS03035	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
GFB59_RS03045	COG1132	(ABC) transporter
GFB59_RS03050	COG1132	(ABC) transporter
GFB59_RS03060	COG2188	Transcriptional regulator
GFB59_RS03065	COG0366	Alpha amylase catalytic
GFB59_RS03070	COG2190	(PTS) system
GFB59_RS03070	COG1263	PTS System
GFB59_RS03070	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GFB59_RS03080	COG0531	amino acid
GFB59_RS03085	COG0039	L-malate dehydrogenase activity
GFB59_RS03090	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
GFB59_RS03095	COG1278	Cold shock
GFB59_RS03110	COG0488	(ABC) transporter
GFB59_RS03115	COG0702	epimerase
GFB59_RS03120	COG0656	L-ascorbic acid biosynthetic process
GFB59_RS03125	COG1113	amino acid transport
GFB59_RS03135	COG0025	NhaP-type Na H and K H
GFB59_RS03165	COG3338	carbonate dehydratase activity
GFB59_RS03185	COG0004	ammonium transporteR
GFB59_RS03195	COG1285	pathogenesis
GFB59_RS03205	COG0488	(ABC) transporter
GFB59_RS03210	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
GFB59_RS03215	COG1573	uracil-dna glycosylase
GFB59_RS03220	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
GFB59_RS03225	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
GFB59_RS03230	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
GFB59_RS03235	COG1215	transferase activity, transferring glycosyl groups
GFB59_RS03235	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
GFB59_RS03240	COG3711	transcriptional antiterminator
GFB59_RS03250	COG2723	6-phospho-beta-galactosidase activity
GFB59_RS03255	COG1447	Phosphotransferase system cellobiose-specific component IIA
GFB59_RS03265	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
GFB59_RS03275	COG1609	Transcriptional regulator
GFB59_RS03280	COG2017	converts alpha-aldose to the beta-anomer
GFB59_RS03290	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GFB59_RS03295	COG3715	PTS system
GFB59_RS03300	COG3716	PTS system mannose fructose sorbose family IID component
GFB59_RS03335	COG3684	Belongs to the aldolase LacD family
GFB59_RS03350	COG1349	DNA-binding transcription factor activity
GFB59_RS03360	COG0420	3'-5' exonuclease activity
GFB59_RS03365	COG0419	ATPase involved in DNA repair
GFB59_RS03380	COG1194	a g-specific adenine glycosylase
GFB59_RS03390	COG2249	NAD(P)H dehydrogenase (quinone) activity
GFB59_RS03405	COG0351	phosphomethylpyrimidine kinase
GFB59_RS03420	COG2910	NAD(P)H-binding
GFB59_RS03425	COG1472	Belongs to the glycosyl hydrolase 3 family
GFB59_RS03440	COG4120	Belongs to the binding-protein-dependent transport system permease family
GFB59_RS03450	COG0604	alcohol dehydrogenase
GFB59_RS03455	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
GFB59_RS03460	COG0463	Glycosyl transferase, family 2
GFB59_RS03465	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
GFB59_RS03475	COG0745	RESPONSE REGULATOR receiver
GFB59_RS03480	COG5002	protein histidine kinase activity
GFB59_RS03490	COG0778	Nitroreductase
GFB59_RS03495	COG1304	FMN binding
GFB59_RS03530	COG0604	alcohol dehydrogenase
GFB59_RS03545	COG0628	permease
GFB59_RS03570	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
GFB59_RS03580	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
GFB59_RS03585	COG3189	MarR family transcriptional regulator
GFB59_RS03610	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
GFB59_RS03635	COG0105	UTP biosynthetic process
GFB59_RS03645	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
GFB59_RS03650	COG2267	carboxylic ester hydrolase activity
GFB59_RS03685	COG2267	carboxylic ester hydrolase activity
GFB59_RS03720	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
GFB59_RS03745	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
GFB59_RS03750	COG0343	queuine tRNA-ribosyltransferase activity
GFB59_RS03755	COG1862	Preprotein translocase
GFB59_RS03760	COG1012	belongs to the aldehyde dehydrogenase family
GFB59_RS03760	COG1454	alcohol dehydrogenase
GFB59_RS03770	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
GFB59_RS03775	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
GFB59_RS03780	COG4109	DRTGG domain
GFB59_RS03785	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
GFB59_RS03790	COG0513	Belongs to the DEAD box helicase family
GFB59_RS03840	COG3118	belongs to the thioredoxin family
GFB59_RS03850	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GFB59_RS03855	COG1696	Membrane protein involved in D-alanine export
GFB59_RS03860	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GFB59_RS03865	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
GFB59_RS03870	COG1719	4-vinyl reductase, 4VR
GFB59_RS03875	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
GFB59_RS03885	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
GFB59_RS03900	COG0668	transmembrane transport
GFB59_RS03915	COG1827	regulation of RNA biosynthetic process
GFB59_RS03920	COG0006	proline dipeptidase activity
GFB59_RS03925	COG1609	Transcriptional regulator
GFB59_RS03930	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GFB59_RS03935	COG1011	Hydrolase
GFB59_RS03975	COG0737	Belongs to the 5'-nucleotidase family
GFB59_RS03980	COG4470	Protein conserved in bacteria
GFB59_RS03985	COG0647	UMP catabolic process
GFB59_RS03995	COG0586	Pfam SNARE associated Golgi protein
GFB59_RS04000	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
GFB59_RS04015	COG1098	S1 RNA binding domain
GFB59_RS04165	COG0531	amino acid
GFB59_RS04170	COG0438	transferase activity, transferring glycosyl groups
GFB59_RS04175	COG0438	transferase activity, transferring glycosyl groups
GFB59_RS04185	COG0436	Aminotransferase
GFB59_RS04195	COG1368	sulfuric ester hydrolase activity
GFB59_RS04200	COG0735	belongs to the Fur family
GFB59_RS04245	COG0477	Major facilitator Superfamily
GFB59_RS04255	COG2814	Major facilitator Superfamily
GFB59_RS04265	COG0671	phosphoesterase, PA-phosphatase related
GFB59_RS04275	COG2244	polysaccharide biosynthetic process
GFB59_RS04280	COG1187	pseudouridine synthase activity
GFB59_RS04290	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
GFB59_RS04310	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
GFB59_RS04320	COG3830	Belongs to the UPF0237 family
GFB59_RS04350	COG2357	RelA SpoT domain protein
GFB59_RS04360	COG0564	pseudouridine synthase activity
GFB59_RS04370	COG3142	Participates in the control of copper homeostasis
GFB59_RS04380	COG2706	6-phosphogluconolactonase activity
GFB59_RS04390	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
GFB59_RS04415	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
GFB59_RS04425	COG1674	ftsk spoiiie
GFB59_RS04430	COG0612	Peptidase, M16
GFB59_RS04435	COG0612	Peptidase, M16
GFB59_RS04440	COG1028	Short-chain dehydrogenase reductase Sdr
GFB59_RS04445	COG1426	Protein conserved in bacteria
GFB59_RS04450	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
GFB59_RS04460	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
GFB59_RS04470	COG1739	Uncharacterized protein family UPF0029
GFB59_RS04475	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
GFB59_RS04505	COG2884	Cell division ATP-binding protein ftsE
GFB59_RS04510	COG2177	Part of the ABC transporter FtsEX involved in
GFB59_RS04520	COG0745	RESPONSE REGULATOR receiver
GFB59_RS04525	COG5002	protein histidine kinase activity
GFB59_RS04535	COG0573	inorganic phosphate transmembrane transporter activity
GFB59_RS04540	COG0581	inorganic phosphate transmembrane transporter activity
GFB59_RS04545	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
GFB59_RS04550	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
GFB59_RS04555	COG0704	Plays a role in the regulation of phosphate uptake
GFB59_RS04575	COG1950	PFAM Membrane protein of
GFB59_RS04585	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
GFB59_RS04595	COG0492	ferredoxin-NADP+ reductase activity
GFB59_RS04600	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GFB59_RS04605	COG0745	RESPONSE REGULATOR receiver
GFB59_RS04615	COG0577	efflux transmembrane transporter activity
GFB59_RS04615	COG1136	(ABC) transporter
GFB59_RS04635	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
GFB59_RS04650	COG0391	Required for morphogenesis under gluconeogenic growth conditions
GFB59_RS04675	COG2390	Transcriptional regulator
GFB59_RS04715	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
GFB59_RS04725	COG0557	exoribonuclease II activity
GFB59_RS04745	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GFB59_RS04770	COG0395	ABC-type sugar transport system, permease component
GFB59_RS04775	COG1175	transmembrane transport
GFB59_RS04780	COG3842	ATPase activity
GFB59_RS04795	COG0561	phosphatase activity
GFB59_RS04805	COG0280	phosphate acetyltransferase
GFB59_RS04810	COG0802	atpase or kinase
GFB59_RS04815	COG4152	abc transporter atp-binding protein
GFB59_RS04820	COG1668	transmembrane transport
GFB59_RS04830	COG0708	Exodeoxyribonuclease III
GFB59_RS04835	COG0812	UDP-N-acetylmuramate dehydrogenase activity
GFB59_RS04845	COG1396	sequence-specific DNA binding
GFB59_RS04845	COG3800	Transcriptional regulator
GFB59_RS04855	COG1176	ABC-type spermidine putrescine transport system, permease component I
GFB59_RS04860	COG1177	transmembrane transport
GFB59_RS04865	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
GFB59_RS04870	COG2336	PFAM SpoVT AbrB
GFB59_RS04880	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
GFB59_RS04885	COG1309	transcriptional regulator
GFB59_RS04915	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
GFB59_RS04935	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
GFB59_RS04940	COG1459	type II secretion system
GFB59_RS04980	COG1113	amino acid transport
GFB59_RS05105	COG2261	transglycosylase associated protein
GFB59_RS05120	COG0745	RESPONSE REGULATOR receiver
GFB59_RS05125	COG5002	protein histidine kinase activity
GFB59_RS05125	COG3850	Histidine kinase
GFB59_RS05155	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
GFB59_RS05215	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GFB59_RS05240	COG2814	Major facilitator Superfamily
GFB59_RS05245	COG0561	phosphatase activity
GFB59_RS05250	COG2326	polyphosphate kinase activity
GFB59_RS05255	COG3590	peptidase
GFB59_RS05300	COG0673	inositol 2-dehydrogenase activity
GFB59_RS05310	COG1447	Phosphotransferase system cellobiose-specific component IIA
GFB59_RS05330	COG0514	ATP-dependent DNA helicase (RecQ)
GFB59_RS05340	COG2309	aminopeptidase activity
GFB59_RS05355	COG1295	ribonuclease BN
GFB59_RS05360	COG0716	FMN binding
GFB59_RS05370	COG0024	Methionine aminopeptidase
GFB59_RS05375	COG0463	Glycosyl transferase, family 2
GFB59_RS05395	COG1210	Utp--glucose-1-phosphate uridylyltransferase
GFB59_RS05405	COG2801	Transposase and inactivated derivatives
GFB59_RS05415	COG2723	6-phospho-beta-galactosidase activity
GFB59_RS05420	COG2190	(PTS) system
GFB59_RS05420	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GFB59_RS05420	COG1263	PTS System
GFB59_RS05425	COG4485	Bacterial membrane protein, YfhO
GFB59_RS05440	COG0463	Glycosyl transferase, family 2
GFB59_RS05450	COG4129	membrane
GFB59_RS05455	COG1278	Cold shock
GFB59_RS05470	COG1705	Flagellar rod assembly protein muramidase FlgJ
GFB59_RS05485	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
GFB59_RS05490	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
GFB59_RS05505	COG1368	sulfuric ester hydrolase activity
GFB59_RS05515	COG4975	Glucose uptake
GFB59_RS05550	COG0590	tRNA wobble adenosine to inosine editing
GFB59_RS05565	COG2814	Major facilitator Superfamily
GFB59_RS05590	COG0588	phosphoglycerate mutase activity
GFB59_RS05615	COG2514	catechol 2,3-dioxygenase activity
GFB59_RS05620	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
GFB59_RS05625	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
GFB59_RS05630	COG1435	thymidine kinase activity
GFB59_RS05640	COG2890	protein-(glutamine-N5) methyltransferase activity
GFB59_RS05645	COG0009	L-threonylcarbamoyladenylate synthase
GFB59_RS05660	COG0356	it plays a direct role in the translocation of protons across the membrane
GFB59_RS05710	COG1077	Cell shape determining protein MreB Mrl
GFB59_RS05730	COG0772	Belongs to the SEDS family
GFB59_RS05735	COG0509	glycine decarboxylation via glycine cleavage system
GFB59_RS05740	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GFB59_RS05745	COG1464	Belongs to the NlpA lipoprotein family
GFB59_RS05765	COG2011	ABC-type metal ion transport system permease component
GFB59_RS05775	COG0719	Fe-S assembly protein
GFB59_RS05780	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
GFB59_RS05785	COG0822	iron-sulfur transferase activity
GFB59_RS05790	COG0719	Fe-S assembly protein
GFB59_RS05825	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
GFB59_RS05830	COG2918	glutathione biosynthetic process
GFB59_RS05830	COG1181	Belongs to the D-alanine--D-alanine ligase family
GFB59_RS05835	COG5506	Protein of unknown function (DUF1694)
GFB59_RS05845	COG1760	l-serine dehydratase
GFB59_RS05850	COG1760	l-serine dehydratase
GFB59_RS05855	COG0406	alpha-ribazole phosphatase activity
GFB59_RS05860	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GFB59_RS05865	COG4221	oxidoreductase activity
GFB59_RS05875	COG1428	Deoxynucleoside kinase
GFB59_RS05885	COG4166	transmembrane transport
GFB59_RS05890	COG2205	protein histidine kinase activity
GFB59_RS05895	COG0745	RESPONSE REGULATOR receiver
GFB59_RS05940	COG3321	synthase
GFB59_RS05940	COG1028	Short-chain dehydrogenase reductase Sdr
GFB59_RS05940	COG0604	alcohol dehydrogenase
GFB59_RS05950	COG0456	acetyltransferase
GFB59_RS05950	COG1214	PFAM Peptidase M22, glycoprotease
GFB59_RS05960	COG1307	EDD domain protein, DegV family
GFB59_RS05970	COG2197	response regulator
GFB59_RS05975	COG4585	Histidine kinase
GFB59_RS05985	COG1131	(ABC) transporter
GFB59_RS06015	COG2183	response to ionizing radiation
GFB59_RS06025	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
GFB59_RS06035	COG3620	sequence-specific DNA binding
GFB59_RS06045	COG1956	GAF domain-containing protein
GFB59_RS06050	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
GFB59_RS06055	COG1104	cysteine desulfurase activity
GFB59_RS06065	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
GFB59_RS06070	COG0525	valine-tRNA ligase activity
GFB59_RS06085	COG2003	Belongs to the UPF0758 family
GFB59_RS06090	COG1077	Cell shape determining protein MreB Mrl
GFB59_RS06095	COG1792	Involved in formation and maintenance of cell shape
GFB59_RS06105	COG0850	regulation of cytokinetic process
GFB59_RS06110	COG2894	cell division
GFB59_RS06115	COG0765	amino acid transport
GFB59_RS06120	COG1126	abc transporter atp-binding protein
GFB59_RS06125	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GFB59_RS06135	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GFB59_RS06155	COG2001	Belongs to the MraZ family
GFB59_RS06170	COG0768	penicillin binding
GFB59_RS06195	COG0849	cell division
GFB59_RS06210	COG0762	integral membrane protein
GFB59_RS06220	COG3599	regulation of cell shape
GFB59_RS06230	COG1278	Cold shock
GFB59_RS06240	COG2814	Major facilitator Superfamily
GFB59_RS06245	COG3853	Toxic anion resistance protein (TelA)
GFB59_RS06270	COG1104	cysteine desulfurase activity
GFB59_RS06285	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
GFB59_RS06305	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
GFB59_RS06315	COG1597	lipid kinase activity
GFB59_RS06355	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
GFB59_RS06380	COG4476	Belongs to the UPF0223 family
GFB59_RS06385	COG0483	inositol monophosphate 1-phosphatase activity
GFB59_RS06390	COG1217	gtp-binding protein TYPA
GFB59_RS06400	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
GFB59_RS06405	COG4471	UPF0298 protein
GFB59_RS06410	COG0742	ribosomal rna small subunit methyltransferase
GFB59_RS06420	COG3480	Lon protease (S16) C-terminal proteolytic domain
GFB59_RS06430	COG2333	competence protein COMEC
GFB59_RS06430	COG0658	competence protein
GFB59_RS06435	COG1466	dna polymerase III delta subunit
GFB59_RS06490	COG1132	(ABC) transporter
GFB59_RS06500	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
GFB59_RS06520	COG0765	amino acid transport
GFB59_RS06525	COG1126	abc transporter atp-binding protein
GFB59_RS06535	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GFB59_RS06535	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GFB59_RS06535	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GFB59_RS06540	COG1105	Belongs to the carbohydrate kinase PfkB family
GFB59_RS06545	COG1349	DNA-binding transcription factor activity
GFB59_RS06555	COG2755	lipolytic protein G-D-S-L family
GFB59_RS06555	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
GFB59_RS06565	COG0300	oxidoreductase activity
GFB59_RS06570	COG5416	Lipopolysaccharide assembly protein A domain
GFB59_RS06575	COG0542	response to heat
GFB59_RS06590	COG0737	Belongs to the 5'-nucleotidase family
GFB59_RS06605	COG0587	DNA-directed DNA polymerase activity
GFB59_RS06625	COG2996	Protein conserved in bacteria
GFB59_RS06640	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
GFB59_RS06645	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
GFB59_RS06650	COG1187	pseudouridine synthase activity
GFB59_RS06655	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
GFB59_RS06670	COG0514	ATP-dependent DNA helicase (RecQ)
GFB59_RS06685	COG0539	negative regulation of cytoplasmic translation
GFB59_RS06705	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GFB59_RS06720	COG0488	(ABC) transporter
GFB59_RS06725	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
GFB59_RS06735	COG1272	protein, Hemolysin III
GFB59_RS06740	COG1307	EDD domain protein, DegV family
GFB59_RS06745	COG2755	lipolytic protein G-D-S-L family
GFB59_RS06750	COG4698	Protein conserved in bacteria
GFB59_RS06755	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GFB59_RS06765	COG3409	Peptidoglycan-binding domain 1 protein
GFB59_RS06765	COG0793	Belongs to the peptidase S41A family
GFB59_RS06805	COG0758	DNA mediated transformation
GFB59_RS06810	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
GFB59_RS06830	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
GFB59_RS06845	COG0187	DNA topoisomerase II activity
GFB59_RS06850	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
GFB59_RS06860	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
GFB59_RS06865	COG0583	DNA-binding transcription factor activity
GFB59_RS06870	COG1227	inorganic diphosphatase activity
GFB59_RS06875	COG4974	Belongs to the 'phage' integrase family
GFB59_RS06880	COG0577	efflux transmembrane transporter activity
GFB59_RS06885	COG1136	(ABC) transporter
GFB59_RS06890	COG5002	protein histidine kinase activity
GFB59_RS06895	COG0745	RESPONSE REGULATOR receiver
GFB59_RS06915	COG0778	Nitroreductase
GFB59_RS06925	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
GFB59_RS06960	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
GFB59_RS06975	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
GFB59_RS06985	COG1307	EDD domain protein, DegV family
GFB59_RS06995	COG1293	RNA-binding protein homologous to eukaryotic snRNP
GFB59_RS07010	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
GFB59_RS07015	COG0284	orotidine-5'-phosphate decarboxylase activity
GFB59_RS07030	COG0505	Belongs to the CarA family
GFB59_RS07035	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
GFB59_RS07045	COG2233	PERMEase
GFB59_RS07050	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
GFB59_RS07055	COG0564	pseudouridine synthase activity
GFB59_RS07060	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
GFB59_RS07075	COG0328	RNA-DNA hybrid ribonuclease activity
GFB59_RS07085	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GFB59_RS07105	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GFB59_RS07110	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GFB59_RS07115	COG0583	DNA-binding transcription factor activity
GFB59_RS07120	COG3590	peptidase
GFB59_RS07125	COG0095	Lipoate-protein ligase
GFB59_RS07140	COG0116	Belongs to the methyltransferase superfamily
GFB59_RS07165	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GFB59_RS07170	COG2131	deaminase
GFB59_RS07175	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
GFB59_RS07190	COG0436	Aminotransferase
GFB59_RS07200	COG1199	ATP-dependent helicase activity
GFB59_RS07200	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
GFB59_RS07215	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
GFB59_RS07230	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
GFB59_RS07230	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
GFB59_RS07245	COG2151	metal-sulfur cluster biosynthetic enzyme
GFB59_RS07255	COG1942	4-Oxalocrotonate Tautomerase
GFB59_RS07260	COG2274	protein secretion by the type I secretion system
GFB59_RS07260	COG3271	cysteine-type peptidase activity
GFB59_RS07270	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
GFB59_RS07275	COG2384	SAM-dependent methyltransferase
GFB59_RS07280	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
GFB59_RS07285	COG0358	DNA primase activity
GFB59_RS07350	COG3953	SLT domain
GFB59_RS07350	COG5280	Phage tail tape measure protein TP901
GFB59_RS07440	COG0629	single-stranded DNA binding
GFB59_RS07495	COG1381	Involved in DNA repair and RecF pathway recombination
GFB59_RS07505	COG0295	cytidine deaminase activity
GFB59_RS07520	COG1702	phosphate starvation-inducible protein PhoH
GFB59_RS07540	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
GFB59_RS07545	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GFB59_RS07550	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GFB59_RS07580	COG4991	sh3 domain protein
GFB59_RS07580	COG0860	N-Acetylmuramoyl-L-alanine amidase
GFB59_RS07580	COG3103	Sh3 type 3 domain protein
GFB59_RS07595	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
GFB59_RS07605	COG1385	rRNA (uridine-N3-)-methyltransferase activity
GFB59_RS07620	COG2094	Belongs to the DNA glycosylase MPG family
GFB59_RS07650	COG2249	NAD(P)H dehydrogenase (quinone) activity
GFB59_RS07700	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
GFB59_RS07710	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
GFB59_RS07710	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
GFB59_RS07745	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
GFB59_RS07755	COG0635	Involved in the biosynthesis of porphyrin-containing compound
GFB59_RS07760	COG0196	riboflavin kinase activity
GFB59_RS07770	COG0861	Integral membrane protein TerC family
GFB59_RS07800	COG0195	Participates in both transcription termination and antitermination
GFB59_RS07820	COG0750	zinc metalloprotease
GFB59_RS07825	COG4589	Belongs to the CDS family
GFB59_RS07830	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
GFB59_RS07840	COG2801	Transposase and inactivated derivatives
GFB59_RS07870	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
GFB59_RS07875	COG0204	Acyl-transferase
GFB59_RS07880	COG0531	amino acid
GFB59_RS07890	COG1132	(ABC) transporter
GFB59_RS07895	COG1132	(ABC) transporter
GFB59_RS07900	COG3763	UPF0154 protein
GFB59_RS07905	COG4224	UPF0291 protein
GFB59_RS07930	COG1837	Belongs to the UPF0109 family
GFB59_RS07940	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
GFB59_RS07960	COG0552	protein localization to endoplasmic reticulum
GFB59_RS07965	COG1196	nuclear chromosome segregation
GFB59_RS07970	COG0571	ribonuclease III activity
GFB59_RS07980	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GFB59_RS07985	COG0601	transmembrane transport
GFB59_RS07990	COG4608	Belongs to the ABC transporter superfamily
GFB59_RS08000	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GFB59_RS08010	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
GFB59_RS08015	COG1461	Dihydroxyacetone kinase
GFB59_RS08030	COG1564	THIamine pyrophosphokinase
GFB59_RS08035	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
GFB59_RS08040	COG1162	GTPase activity
GFB59_RS08045	COG2815	serine threonine protein kinase
GFB59_RS08045	COG0515	serine threonine protein kinase
GFB59_RS08055	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
GFB59_RS08055	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
GFB59_RS08065	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
GFB59_RS08070	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
GFB59_RS08080	COG0194	GDP metabolic process
GFB59_RS08095	COG0497	DNA recombination
GFB59_RS08100	COG1438	arginine binding
GFB59_RS08105	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
GFB59_RS08115	COG1722	exodeoxyribonuclease VII activity
GFB59_RS08135	COG1302	Protein conserved in bacteria
GFB59_RS08140	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
GFB59_RS08145	COG0006	proline dipeptidase activity
GFB59_RS08150	COG0211	Belongs to the bacterial ribosomal protein bL27 family
GFB59_RS08155	COG2868	ribosomal protein
GFB59_RS08160	COG0261	This protein binds to 23S rRNA in the presence of protein L20
GFB59_RS08185	COG2936	dipeptidyl-peptidase activity
GFB59_RS08195	COG0789	Transcriptional regulator
GFB59_RS08200	COG1982	Orn Lys Arg decarboxylase major
GFB59_RS08205	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
GFB59_RS08220	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GFB59_RS08225	COG1940	carbohydrate kinase activity
GFB59_RS08235	COG0705	Rhomboid family
GFB59_RS08235	COG0457	Tetratricopeptide repeat
GFB59_RS08240	COG0768	penicillin binding
GFB59_RS08250	COG4841	protein insertion into membrane
GFB59_RS08255	COG2197	response regulator
GFB59_RS08260	COG4585	Histidine kinase
GFB59_RS08270	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
GFB59_RS08275	COG0572	uridine kinase
GFB59_RS08280	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
GFB59_RS08285	COG0072	phenylalanine-tRNA ligase activity
GFB59_RS08295	COG1733	regulation of RNA biosynthetic process
GFB59_RS08305	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GFB59_RS08315	COG0706	membrane insertase activity
GFB59_RS08320	COG5002	protein histidine kinase activity
GFB59_RS08325	COG0745	RESPONSE REGULATOR receiver
GFB59_RS08330	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
GFB59_RS08335	COG0741	lytic transglycosylase activity
GFB59_RS08335	COG1196	nuclear chromosome segregation
GFB59_RS08335	COG0739	heme binding
GFB59_RS08360	COG2226	methyltransferase
GFB59_RS08365	COG0799	negative regulation of ribosome biogenesis
GFB59_RS08375	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
GFB59_RS08380	COG1534	Rna-binding protein
GFB59_RS08385	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
GFB59_RS08390	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
GFB59_RS08395	COG0346	lactoylglutathione lyase activity
GFB59_RS08405	COG0400	carboxylic ester hydrolase activity
GFB59_RS08430	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
GFB59_RS08475	COG1484	DNA-dependent DNA replication
GFB59_RS08490	COG0237	dephospho-CoA kinase activity
GFB59_RS08495	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
GFB59_RS08500	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GFB59_RS08500	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GFB59_RS08505	COG0670	Belongs to the BI1 family
GFB59_RS08540	COG1674	ftsk spoiiie
GFB59_RS08550	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GFB59_RS08555	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GFB59_RS08580	COG1131	(ABC) transporter
GFB59_RS08585	COG0537	adenosine 5'-monophosphoramidase activity
GFB59_RS08595	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GFB59_RS08600	COG3481	metal-dependent phosphohydrolase, HD sub domain
GFB59_RS08610	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GFB59_RS08615	COG0564	pseudouridine synthase activity
GFB59_RS08620	COG1438	arginine binding
GFB59_RS08625	COG0018	arginyl-trna synthetase
GFB59_RS08645	COG0167	dihydroorotate dehydrogenase activity
GFB59_RS08660	COG1393	Belongs to the ArsC family
GFB59_RS08665	COG1234	tRNA 3'-trailer cleavage
GFB59_RS08680	COG1136	(ABC) transporter
GFB59_RS08685	COG0745	RESPONSE REGULATOR receiver
GFB59_RS08690	COG0642	Histidine kinase
GFB59_RS08695	COG0602	queuosine metabolic process
GFB59_RS08705	COG3682	Transcriptional regulator
GFB59_RS08710	COG0151	Belongs to the GarS family
GFB59_RS08720	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
GFB59_RS08725	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
GFB59_RS08745	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
GFB59_RS08755	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
GFB59_RS08770	COG2814	Major facilitator Superfamily
GFB59_RS08780	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
GFB59_RS08790	COG0542	response to heat
GFB59_RS08805	COG1253	flavin adenine dinucleotide binding
GFB59_RS08810	COG0628	permease
GFB59_RS08815	COG2153	protein acetylation
GFB59_RS08825	COG3557	Belongs to the UPF0374 family
GFB59_RS08845	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GFB59_RS08855	COG0028	Belongs to the TPP enzyme family
GFB59_RS08860	COG3425	synthase
GFB59_RS08870	COG0183	Belongs to the thiolase family
GFB59_RS08890	COG2017	converts alpha-aldose to the beta-anomer
GFB59_RS08895	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GFB59_RS08915	COG3091	SprT-like family
GFB59_RS08920	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
GFB59_RS08925	COG4120	Belongs to the binding-protein-dependent transport system permease family
GFB59_RS08960	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
GFB59_RS08965	COG2188	Transcriptional regulator
GFB59_RS08970	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
GFB59_RS08975	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
GFB59_RS08980	COG4946	Tricorn protease homolog
GFB59_RS08980	COG1506	peptidase
GFB59_RS08980	COG0823	Involved in the tonB-independent uptake of proteins
GFB59_RS09015	COG3104	oligopeptide transport
GFB59_RS09020	COG0577	efflux transmembrane transporter activity
GFB59_RS09020	COG1136	(ABC) transporter
GFB59_RS09035	COG2211	Major facilitator Superfamily
GFB59_RS09070	COG2755	lipolytic protein G-D-S-L family
GFB59_RS09070	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
GFB59_RS09150	COG0833	amino acid
GFB59_RS09160	COG0028	Belongs to the TPP enzyme family
GFB59_RS09190	COG3177	Filamentation induced by cAMP protein fic
GFB59_RS09195	COG0564	pseudouridine synthase activity
GFB59_RS09215	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
GFB59_RS09265	COG0511	ligase activity, forming carbon-carbon bonds
GFB59_RS09275	COG2851	Citrate transporter
GFB59_RS09310	COG0778	Nitroreductase
GFB59_RS09315	COG1131	(ABC) transporter
GFB59_RS09325	COG1309	transcriptional regulator
GFB59_RS09330	COG2814	Major facilitator Superfamily
GFB59_RS09350	COG2801	Transposase and inactivated derivatives
GFB59_RS09365	COG1131	(ABC) transporter
GFB59_RS09375	COG4608	Belongs to the ABC transporter superfamily
GFB59_RS09380	COG0444	Belongs to the ABC transporter superfamily
GFB59_RS09390	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GFB59_RS09395	COG0601	transmembrane transport
GFB59_RS09400	COG4166	transmembrane transport
GFB59_RS09410	COG1132	(ABC) transporter
GFB59_RS09415	COG1121	(ABC) transporter
GFB59_RS09435	COG5549	protein import
GFB59_RS09435	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GFB59_RS09495	COG0519	Catalyzes the synthesis of GMP from XMP
GFB59_RS09515	COG4690	dipeptidase activity
GFB59_RS09520	COG1607	acyl-coa hydrolase
GFB59_RS09525	COG3973	AAA domain
GFB59_RS09535	COG0569	domain protein
GFB59_RS09535	COG0475	glutathione-regulated potassium exporter activity
GFB59_RS09540	COG2267	carboxylic ester hydrolase activity
GFB59_RS09550	COG1914	H( )-stimulated, divalent metal cation uptake system
GFB59_RS09560	COG0588	phosphoglycerate mutase activity
GFB59_RS09565	COG0235	Class ii aldolase
GFB59_RS09575	COG1136	(ABC) transporter
GFB59_RS09580	COG0531	amino acid
GFB59_RS09590	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
GFB59_RS09595	COG0726	polysaccharide deacetylase
GFB59_RS09610	COG0489	protein tyrosine kinase activity
GFB59_RS09630	COG1216	Glycosyl transferase, family 2
GFB59_RS09630	COG1442	glycosyl transferase family 8
GFB59_RS09655	COG0463	Glycosyl transferase, family 2
GFB59_RS09660	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
GFB59_RS09670	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
GFB59_RS09680	COG0463	Glycosyl transferase, family 2
GFB59_RS09690	COG0765	amino acid transport
GFB59_RS09695	COG0765	amino acid transport
GFB59_RS09700	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GFB59_RS09720	COG0735	belongs to the Fur family
GFB59_RS09730	COG0194	GDP metabolic process
GFB59_RS09735	COG0456	acetyltransferase
GFB59_RS09750	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
GFB59_RS09775	COG0058	SHG alpha-glucan phosphorylase activity
GFB59_RS09785	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
GFB59_RS09795	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
GFB59_RS09800	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
GFB59_RS09810	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GFB59_RS09820	COG1393	Belongs to the ArsC family
GFB59_RS09830	COG4464	protein tyrosine phosphatase activity
GFB59_RS09835	COG1316	TRANSCRIPTIONal
GFB59_RS09840	COG1088	dTDP-glucose 4,6-dehydratase activity
GFB59_RS09865	COG1442	glycosyl transferase family 8
GFB59_RS09865	COG1216	Glycosyl transferase, family 2
GFB59_RS09870	COG0438	transferase activity, transferring glycosyl groups
GFB59_RS09940	COG0562	UDP-galactopyranose mutase
GFB59_RS09945	COG0489	protein tyrosine kinase activity
GFB59_RS09960	COG4708	membrane
GFB59_RS09965	COG1028	Short-chain dehydrogenase reductase Sdr
GFB59_RS09985	COG4608	Belongs to the ABC transporter superfamily
GFB59_RS09990	COG0444	Belongs to the ABC transporter superfamily
GFB59_RS09995	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GFB59_RS10000	COG0601	transmembrane transport
GFB59_RS10005	COG4166	transmembrane transport
GFB59_RS10010	COG4166	transmembrane transport
GFB59_RS10015	COG2814	Major facilitator Superfamily
GFB59_RS10020	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
GFB59_RS10025	COG1556	Lactate utilization protein
GFB59_RS10030	COG1139	Iron-sulfur cluster binding protein
GFB59_RS10035	COG0247	lactate metabolic process
GFB59_RS10045	COG1447	Phosphotransferase system cellobiose-specific component IIA
GFB59_RS10065	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GFB59_RS10100	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GFB59_RS10190	COG0366	Alpha amylase catalytic
GFB59_RS10195	COG1609	Transcriptional regulator
GFB59_RS10210	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
GFB59_RS10225	COG0439	Biotin carboxylase
GFB59_RS10235	COG0511	ligase activity, forming carbon-carbon bonds
GFB59_RS10240	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GFB59_RS10245	COG1028	Short-chain dehydrogenase reductase Sdr
GFB59_RS10255	COG2070	2-Nitropropane dioxygenase
GFB59_RS10265	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GFB59_RS10275	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
GFB59_RS10285	COG1979	alcohol dehydrogenase
GFB59_RS10320	COG1846	Transcriptional regulator
GFB59_RS10325	COG0494	nUDIX hydrolase
GFB59_RS10335	COG0640	Transcriptional regulator
GFB59_RS10340	COG0588	phosphoglycerate mutase activity
GFB59_RS10360	COG0628	permease
GFB59_RS10370	COG2246	polysaccharide biosynthetic process
GFB59_RS10375	COG0028	Belongs to the TPP enzyme family
GFB59_RS10420	COG0460	homoserine dehydrogenase
GFB59_RS10425	COG0527	aspartate kinase activity
GFB59_RS10430	COG2268	Band 7 protein
GFB59_RS10450	COG0436	Aminotransferase
GFB59_RS10460	COG0596	Alpha beta hydrolase
GFB59_RS10465	COG1309	transcriptional regulator
GFB59_RS10470	COG1511	domain protein
GFB59_RS10470	COG1511	domain protein
GFB59_RS10480	COG0367	asparagine synthase
GFB59_RS10495	COG0142	geranyltranstransferase activity
GFB59_RS10505	COG4152	abc transporter atp-binding protein
GFB59_RS10520	COG1131	(ABC) transporter
GFB59_RS10530	COG1028	Short-chain dehydrogenase reductase Sdr
GFB59_RS10535	COG2723	6-phospho-beta-galactosidase activity
GFB59_RS10540	COG2190	(PTS) system
GFB59_RS10540	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GFB59_RS10540	COG1263	PTS System
GFB59_RS10545	COG3711	transcriptional antiterminator
GFB59_RS10550	COG1132	(ABC) transporter
GFB59_RS10555	COG1132	(ABC) transporter
GFB59_RS10585	COG1518	maintenance of DNA repeat elements
GFB59_RS10590	COG3513	CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
GFB59_RS10595	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
GFB59_RS10600	COG4988	ABC transporter
GFB59_RS10605	COG1294	oxidase, subunit
GFB59_RS10610	COG1271	oxidase subunit
GFB59_RS10640	COG0697	spore germination
GFB59_RS10645	COG0519	Catalyzes the synthesis of GMP from XMP
GFB59_RS10660	COG2365	Tyrosine phosphatase family
GFB59_RS10665	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
GFB59_RS10675	COG1268	BioY protein
GFB59_RS10695	COG0505	Belongs to the CarA family
GFB59_RS10705	COG1253	flavin adenine dinucleotide binding
GFB59_RS10720	COG2814	Major facilitator Superfamily
GFB59_RS10745	COG0531	amino acid
GFB59_RS10765	COG1266	CAAX protease self-immunity
GFB59_RS10770	COG1316	TRANSCRIPTIONal
GFB59_RS10780	COG1131	(ABC) transporter
GFB59_RS10785	COG1725	Transcriptional regulator
GFB59_RS10790	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
GFB59_RS10795	COG0488	(ABC) transporter
GFB59_RS10800	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GFB59_RS10815	COG1214	PFAM Peptidase M22, glycoprotease
GFB59_RS10850	COG0470	DNA polymerase III
GFB59_RS10855	COG3870	Protein conserved in bacteria
GFB59_RS10880	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
GFB59_RS10890	COG0590	tRNA wobble adenosine to inosine editing
GFB59_RS10900	COG2813	Specifically methylates the guanine in position
GFB59_RS10905	COG0392	lysyltransferase activity
GFB59_RS10905	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
GFB59_RS10915	COG1609	Transcriptional regulator
GFB59_RS10955	COG0477	Major facilitator Superfamily
GFB59_RS10970	COG0438	transferase activity, transferring glycosyl groups
GFB59_RS10975	COG0438	transferase activity, transferring glycosyl groups
GFB59_RS10980	COG1012	belongs to the aldehyde dehydrogenase family
GFB59_RS11000	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
GFB59_RS11010	COG2096	Adenosyltransferase
GFB59_RS11040	COG0250	Participates in transcription elongation, termination and antitermination
GFB59_RS11075	COG4939	FMN-binding domain protein
GFB59_RS11120	COG1131	(ABC) transporter
GFB59_RS11145	COG3688	RNA-binding protein containing a PIN domain
GFB59_RS11155	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
GFB59_RS11165	COG1396	sequence-specific DNA binding
GFB59_RS11170	COG0277	FAD linked oxidase domain protein
GFB59_RS11185	COG4377	Putative membrane peptidase family (DUF2324)
GFB59_RS11195	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GFB59_RS11200	COG4932	domain protein
GFB59_RS11200	COG4886	Leucine-rich repeat (LRR) protein
GFB59_RS11205	COG4956	integral membrane protein (PIN domain superfamily)
GFB59_RS11210	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
GFB59_RS11215	COG0756	dUTP diphosphatase activity
GFB59_RS11220	COG2388	GCN5-related N-acetyl-transferase
GFB59_RS11245	COG1131	(ABC) transporter
GFB59_RS11255	COG0574	Belongs to the PEP-utilizing enzyme family
GFB59_RS11255	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
GFB59_RS11260	COG0517	IMP dehydrogenase activity
GFB59_RS11265	COG0588	phosphoglycerate mutase activity
GFB59_RS11280	COG1304	FMN binding
GFB59_RS11330	COG1309	transcriptional regulator
GFB59_RS11340	COG1131	(ABC) transporter
GFB59_RS11345	COG0783	Belongs to the Dps family
GFB59_RS11450	COG1695	Transcriptional regulator
GFB59_RS11475	COG2801	Transposase and inactivated derivatives
GFB59_RS11500	COG2274	protein secretion by the type I secretion system
GFB59_RS11515	COG3279	Response regulator of the LytR AlgR family
GFB59_RS11575	COG4989	oxidoreductase activity
GFB59_RS11580	COG4221	oxidoreductase activity
GFB59_RS11585	COG1902	pentaerythritol trinitrate reductase activity
GFB59_RS11595	COG0114	fumarate hydratase activity
GFB59_RS11620	COG1914	H( )-stimulated, divalent metal cation uptake system
GFB59_RS11625	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
GFB59_RS11635	COG2814	Major facilitator Superfamily
GFB59_RS11665	COG1108	ABC-type Mn2 Zn2 transport systems permease components
GFB59_RS11670	COG1121	(ABC) transporter
GFB59_RS11700	COG0803	Belongs to the bacterial solute-binding protein 9 family
GFB59_RS11710	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
GFB59_RS11745	COG1116	anion transmembrane transporter activity
GFB59_RS11750	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GFB59_RS11780	COG2801	Transposase and inactivated derivatives
GFB59_RS11810	COG1136	(ABC) transporter
GFB59_RS11820	COG0789	Transcriptional regulator
GFB59_RS11895	COG0200	Binds to the 23S rRNA
GFB59_RS12005	COG0450	alkyl hydroperoxide reductase
GFB59_RS12045	COG0542	response to heat
GFB59_RS12050	COG4463	regulation of RNA biosynthetic process
GFB59_RS12120	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
GFB59_RS12125	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
GFB59_RS12140	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
GFB59_RS12145	COG0037	tRNA processing
GFB59_RS12150	COG1098	S1 RNA binding domain
GFB59_RS12160	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
GFB59_RS12165	COG2244	polysaccharide biosynthetic process
GFB59_RS12170	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
GFB59_RS12180	COG0039	L-malate dehydrogenase activity
GFB59_RS12195	COG1511	domain protein
GFB59_RS12195	COG1511	domain protein
GFB59_RS12210	COG1376	ErfK ybiS ycfS ynhG family protein
GFB59_RS12215	COG0493	'glutamate synthase
GFB59_RS12220	COG0070	glutamate synthase
GFB59_RS12220	COG0067	glutamate synthase
GFB59_RS12220	COG0069	glutamate synthase activity
GFB59_RS12225	COG4708	membrane
GFB59_RS12235	COG2337	Toxic component of a toxin-antitoxin (TA) module
GFB59_RS12260	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
GFB59_RS12290	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
GFB59_RS12300	COG0504	CTP synthase activity
GFB59_RS12310	COG1252	NADH dehydrogenase
GFB59_RS12340	COG0095	Lipoate-protein ligase
GFB59_RS12345	COG1078	dGTPase activity
GFB59_RS12375	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
GFB59_RS12380	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
GFB59_RS12390	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
GFB59_RS12395	COG4619	ABC transporter
GFB59_RS12400	COG0390	transport system, permease component
GFB59_RS12410	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
GFB59_RS12415	COG4466	Protein conserved in bacteria
GFB59_RS12420	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
GFB59_RS12425	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
GFB59_RS12430	COG0084	hydrolase, TatD family'
GFB59_RS12440	COG3684	Belongs to the aldolase LacD family
GFB59_RS12450	COG3279	Response regulator of the LytR AlgR family
GFB59_RS12455	COG3290	protein histidine kinase activity
GFB59_RS12460	COG1132	(ABC) transporter
GFB59_RS12465	COG1132	(ABC) transporter
GFB59_RS12480	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GFB59_RS12480	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GFB59_RS12490	COG1801	Protein of unknown function DUF72
GFB59_RS12510	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
GFB59_RS12525	COG1881	PFAM PEBP family protein
GFB59_RS12535	COG4086	secreted protein
GFB59_RS12540	COG0248	Ppx GppA phosphatase
GFB59_RS12545	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
GFB59_RS12555	COG4989	oxidoreductase activity
GFB59_RS12560	COG2226	methyltransferase
GFB59_RS12570	COG0534	Mate efflux family protein
GFB59_RS12580	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
GFB59_RS12585	COG1704	LemA family
GFB59_RS12600	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GFB59_RS12610	COG1174	glycine betaine transport
GFB59_RS12620	COG3973	AAA domain
GFB59_RS12625	COG0583	DNA-binding transcription factor activity
GFB59_RS12650	COG0640	Transcriptional regulator
GFB59_RS12670	COG1418	mRNA catabolic process
GFB59_RS12680	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
GFB59_RS12685	COG0667	Aldo Keto reductase
GFB59_RS12690	COG0561	phosphatase activity
GFB59_RS12735	COG0588	phosphoglycerate mutase activity
GFB59_RS12740	COG0561	phosphatase activity
GFB59_RS12755	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GFB59_RS12770	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
GFB59_RS12775	COG1811	Na channel or pump
GFB59_RS12785	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GFB59_RS12785	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GFB59_RS12785	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GFB59_RS12790	COG1105	Belongs to the carbohydrate kinase PfkB family
GFB59_RS12800	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
GFB59_RS12815	COG2801	Transposase and inactivated derivatives
GFB59_RS12830	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
GFB59_RS12830	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GFB59_RS12835	COG3715	PTS system
GFB59_RS12840	COG3716	PTS system mannose fructose sorbose family IID component
GFB59_RS12845	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
GFB59_RS12850	COG0163	prenyltransferase activity
GFB59_RS12875	COG0477	Major facilitator Superfamily
GFB59_RS12885	COG4948	Mandelate Racemase Muconate Lactonizing
GFB59_RS12890	COG3775	system Galactitol-specific IIC component
GFB59_RS12895	COG3414	Phosphotransferase system galactitol-specific IIB component
GFB59_RS12900	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GFB59_RS12905	COG0800	Aldolase
GFB59_RS12915	COG1447	Phosphotransferase system cellobiose-specific component IIA
GFB59_RS12925	COG2723	6-phospho-beta-galactosidase activity
GFB59_RS12945	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GFB59_RS12950	COG2188	Transcriptional regulator
GFB59_RS12970	COG2814	Major facilitator Superfamily
GFB59_RS12975	COG1070	Carbohydrate kinase
GFB59_RS12985	COG0235	Class ii aldolase
GFB59_RS12990	COG4806	L-rhamnose isomerase
GFB59_RS12995	COG3254	rhamnose metabolic process
GFB59_RS13000	COG1070	Carbohydrate kinase
GFB59_RS13005	COG2814	Major facilitator Superfamily
GFB59_RS13030	COG0366	Alpha amylase catalytic
GFB59_RS13040	COG2801	Transposase and inactivated derivatives
GFB59_RS13060	COG1263	PTS System
GFB59_RS13060	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GFB59_RS13075	COG1263	PTS System
GFB59_RS13075	COG2190	(PTS) system
GFB59_RS13075	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GFB59_RS13095	COG3964	amidohydrolase
GFB59_RS13140	COG3732	PTS system glucitol sorbitol-specific
GFB59_RS13145	COG3730	PTS system glucitol sorbitol-specific
GFB59_RS13155	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GFB59_RS13155	COG3711	transcriptional antiterminator
GFB59_RS13180	COG0561	phosphatase activity
GFB59_RS13185	COG3623	hexulose-6-phosphate isomerase
GFB59_RS13195	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
GFB59_RS13210	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GFB59_RS13240	COG1446	asparaginase
GFB59_RS13245	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GFB59_RS13250	COG2188	Transcriptional regulator
GFB59_RS13270	COG1070	Carbohydrate kinase
GFB59_RS13275	COG1063	alcohol dehydrogenase
GFB59_RS13280	COG3716	PTS system mannose fructose sorbose family IID component
GFB59_RS13290	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
GFB59_RS13290	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GFB59_RS13305	COG3711	transcriptional antiterminator
GFB59_RS13305	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GFB59_RS13315	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
GFB59_RS13320	COG3775	system Galactitol-specific IIC component
GFB59_RS13335	COG0191	fructose-bisphosphate aldolase activity
GFB59_RS13340	COG2188	Transcriptional regulator
GFB59_RS13350	COG1051	belongs to the nudix hydrolase family
GFB59_RS13375	COG1335	isochorismatase
GFB59_RS13380	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
GFB59_RS13385	COG0584	glycerophosphoryl diester phosphodiesterase
GFB59_RS13390	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
GFB59_RS13400	COG0395	ABC-type sugar transport system, permease component
GFB59_RS13410	COG3842	ATPase activity
GFB59_RS13425	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
GFB59_RS13440	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GFB59_RS13445	COG3716	PTS system mannose fructose sorbose family IID component
GFB59_RS13460	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
GFB59_RS13465	COG0656	L-ascorbic acid biosynthetic process
GFB59_RS13470	COG0789	Transcriptional regulator
GFB59_RS13485	COG2076	Multidrug Resistance protein
GFB59_RS13515	COG2365	Tyrosine phosphatase family
GFB59_RS13565	COG2217	Heavy metal translocating P-type atpase
GFB59_RS13570	COG0071	Belongs to the small heat shock protein (HSP20) family
GFB59_RS13580	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GFB59_RS13585	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
GFB59_RS13600	COG5002	protein histidine kinase activity
GFB59_RS13605	COG0745	RESPONSE REGULATOR receiver
GFB59_RS13615	COG0765	amino acid transport
GFB59_RS13640	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GFB59_RS13645	COG2188	Transcriptional regulator
GFB59_RS13650	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GFB59_RS13655	COG1447	Phosphotransferase system cellobiose-specific component IIA
GFB59_RS13675	COG1335	isochorismatase
GFB59_RS13680	COG2814	Major facilitator Superfamily
GFB59_RS13685	COG2807	transmembrane transport
GFB59_RS13690	COG0667	Aldo Keto reductase
GFB59_RS13705	COG3716	PTS system mannose fructose sorbose family IID component
GFB59_RS13710	COG3715	PTS system
GFB59_RS13750	COG3409	Peptidoglycan-binding domain 1 protein
GFB59_RS13760	COG0765	amino acid transport
GFB59_RS13765	COG1126	abc transporter atp-binding protein
GFB59_RS13805	COG4778	phosphonate C-P lyase system protein PhnL
GFB59_RS13810	COG3001	Fructosamine kinase
GFB59_RS13815	COG1126	abc transporter atp-binding protein
GFB59_RS13820	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GFB59_RS13825	COG0765	amino acid transport
GFB59_RS13840	COG0714	Associated with various cellular activities
GFB59_RS13850	COG1305	Transglutaminase-like
GFB59_RS13855	COG0438	transferase activity, transferring glycosyl groups
GFB59_RS13865	COG2801	Transposase and inactivated derivatives
GFB59_RS13900	COG3493	citrate carrier protein
GFB59_RS13905	COG3290	protein histidine kinase activity
GFB59_RS13910	COG4565	transcriptional regulatory protein
GFB59_RS13945	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
GFB59_RS13965	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
GFB59_RS13970	COG3711	transcriptional antiterminator
GFB59_RS13975	COG2213	PTS system mannitol-specific
GFB59_RS13990	COG0561	phosphatase activity
GFB59_RS14020	COG0577	efflux transmembrane transporter activity
GFB59_RS14020	COG1136	(ABC) transporter
GFB59_RS14040	COG0436	Aminotransferase
GFB59_RS14045	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
GFB59_RS14055	COG0371	Dehydrogenase
GFB59_RS14070	COG1473	amidohydrolase
GFB59_RS14095	COG1132	(ABC) transporter
GFB59_RS14115	COG0706	membrane insertase activity
GFB59_RS14135	COG1472	Belongs to the glycosyl hydrolase 3 family
GFB59_RS14150	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
GFB59_RS14165	COG1447	Phosphotransferase system cellobiose-specific component IIA
GFB59_RS14175	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GFB59_RS14175	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GFB59_RS14180	COG3711	transcriptional antiterminator
GFB59_RS14185	COG1215	transferase activity, transferring glycosyl groups
GFB59_RS14230	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GFB59_RS14340	COG1192	Involved in chromosome partitioning