locus-tag	class	description
GSF71_RS00010	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
GSF71_RS00015	COG0828	Belongs to the bacterial ribosomal protein bS21 family
GSF71_RS00020	COG1610	YqeY-like protein
GSF71_RS00025	COG1702	phosphate starvation-inducible protein PhoH
GSF71_RS00030	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
GSF71_RS00035	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
GSF71_RS00045	COG1381	Involved in DNA repair and RecF pathway recombination
GSF71_RS00050	COG0752	glycyl-tRNA synthetase alpha subunit
GSF71_RS00055	COG0751	glycine-tRNA ligase activity
GSF71_RS00060	COG3189	MarR family transcriptional regulator
GSF71_RS00065	COG0358	DNA primase activity
GSF71_RS00070	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
GSF71_RS00080	COG2384	SAM-dependent methyltransferase
GSF71_RS00085	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
GSF71_RS00090	COG2195	Cleaves the N-terminal amino acid of tripeptides
GSF71_RS00095	COG0710	3-dehydroquinate dehydratase activity
GSF71_RS00110	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
GSF71_RS00115	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
GSF71_RS00120	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
GSF71_RS00125	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
GSF71_RS00145	COG1942	4-Oxalocrotonate Tautomerase
GSF71_RS00150	COG0561	phosphatase activity
GSF71_RS00155	COG2151	metal-sulfur cluster biosynthetic enzyme
GSF71_RS00170	COG1304	FMN binding
GSF71_RS00185	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
GSF71_RS00190	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
GSF71_RS00195	COG1074	ATP-dependent DNA helicase activity
GSF71_RS00200	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
GSF71_RS00200	COG1199	ATP-dependent helicase activity
GSF71_RS00210	COG0017	Asparaginyl-tRNA synthetase
GSF71_RS00220	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
GSF71_RS00225	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GSF71_RS00230	COG3331	DNA recombination
GSF71_RS00235	COG4474	Belongs to the UPF0398 family
GSF71_RS00240	COG3599	regulation of cell shape
GSF71_RS00250	COG0116	Belongs to the methyltransferase superfamily
GSF71_RS00255	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GSF71_RS00265	COG0582	viral genome integration into host DNA
GSF71_RS00285	COG2188	Transcriptional regulator
GSF71_RS00290	COG1131	(ABC) transporter
GSF71_RS00305	COG1131	(ABC) transporter
GSF71_RS00325	COG0095	Lipoate-protein ligase
GSF71_RS00330	COG3655	Transcriptional regulator
GSF71_RS00365	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GSF71_RS00380	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GSF71_RS00385	COG0328	RNA-DNA hybrid ribonuclease activity
GSF71_RS00395	COG1278	Cold shock
GSF71_RS00400	COG2759	Belongs to the formate--tetrahydrofolate ligase family
GSF71_RS00405	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
GSF71_RS00410	COG0564	pseudouridine synthase activity
GSF71_RS00415	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
GSF71_RS00425	COG0540	Belongs to the ATCase OTCase family
GSF71_RS00430	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
GSF71_RS00435	COG0505	Belongs to the CarA family
GSF71_RS00445	COG0543	2 iron, 2 sulfur cluster binding
GSF71_RS00450	COG0167	dihydroorotate dehydrogenase activity
GSF71_RS00455	COG0284	orotidine-5'-phosphate decarboxylase activity
GSF71_RS00465	COG1293	RNA-binding protein homologous to eukaryotic snRNP
GSF71_RS00470	COG1307	EDD domain protein, DegV family
GSF71_RS00480	COG1272	protein, Hemolysin III
GSF71_RS00485	COG1307	EDD domain protein, DegV family
GSF71_RS00500	COG4974	Belongs to the 'phage' integrase family
GSF71_RS00520	COG1227	inorganic diphosphatase activity
GSF71_RS00525	COG0583	DNA-binding transcription factor activity
GSF71_RS00530	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
GSF71_RS00535	COG1882	Formate acetyltransferase
GSF71_RS00540	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
GSF71_RS00545	COG0187	DNA topoisomerase II activity
GSF71_RS00550	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
GSF71_RS00555	COG0390	transport system, permease component
GSF71_RS00560	COG4619	ABC transporter
GSF71_RS00565	COG0351	phosphomethylpyrimidine kinase
GSF71_RS00570	COG3527	Alpha-acetolactate decarboxylase
GSF71_RS00575	COG0028	Belongs to the TPP enzyme family
GSF71_RS00585	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
GSF71_RS00600	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
GSF71_RS00605	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
GSF71_RS00610	COG1959	2 iron, 2 sulfur cluster binding
GSF71_RS00615	COG0702	epimerase
GSF71_RS00620	COG0758	DNA mediated transformation
GSF71_RS00625	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
GSF71_RS00650	COG4479	Belongs to the UPF0346 family
GSF71_RS00660	COG2755	lipolytic protein G-D-S-L family
GSF71_RS00665	COG1307	EDD domain protein, DegV family
GSF71_RS00675	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
GSF71_RS00680	COG0488	(ABC) transporter
GSF71_RS00690	COG0617	tRNA 3'-terminal CCA addition
GSF71_RS00695	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GSF71_RS00705	COG1733	regulation of RNA biosynthetic process
GSF71_RS00710	COG3397	chitin binding
GSF71_RS00715	COG2814	Major facilitator Superfamily
GSF71_RS00730	COG1136	(ABC) transporter
GSF71_RS00730	COG0577	efflux transmembrane transporter activity
GSF71_RS00735	COG0457	Tetratricopeptide repeat
GSF71_RS00745	COG1160	GTP binding
GSF71_RS00750	COG0539	negative regulation of cytoplasmic translation
GSF71_RS00755	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
GSF71_RS00765	COG0514	ATP-dependent DNA helicase (RecQ)
GSF71_RS00780	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
GSF71_RS00785	COG1187	pseudouridine synthase activity
GSF71_RS00790	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
GSF71_RS00795	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
GSF71_RS00810	COG0735	belongs to the Fur family
GSF71_RS00815	COG2996	Protein conserved in bacteria
GSF71_RS00820	COG2707	UPF0756 membrane protein
GSF71_RS00835	COG0587	DNA-directed DNA polymerase activity
GSF71_RS00850	COG0531	amino acid
GSF71_RS00860	COG0333	Belongs to the bacterial ribosomal protein bL32 family
GSF71_RS00865	COG0542	response to heat
GSF71_RS00870	COG5416	Lipopolysaccharide assembly protein A domain
GSF71_RS00875	COG0300	oxidoreductase activity
GSF71_RS00880	COG1234	tRNA 3'-trailer cleavage
GSF71_RS00890	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
GSF71_RS00900	COG1349	DNA-binding transcription factor activity
GSF71_RS00905	COG1105	Belongs to the carbohydrate kinase PfkB family
GSF71_RS00915	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
GSF71_RS00925	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GSF71_RS00930	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
GSF71_RS00940	COG0322	excinuclease ABC activity
GSF71_RS00945	COG1126	abc transporter atp-binding protein
GSF71_RS00950	COG0765	amino acid transport
GSF71_RS00960	COG0218	Necessary for normal cell division and for the maintenance of normal septation
GSF71_RS00965	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
GSF71_RS00970	COG0544	peptidyl-prolyl cis-trans isomerase activity
GSF71_RS00975	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
GSF71_RS00990	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
GSF71_RS00995	COG0268	Binds directly to 16S ribosomal RNA
GSF71_RS01000	COG1466	dna polymerase III delta subunit
GSF71_RS01005	COG0658	competence protein
GSF71_RS01005	COG2333	competence protein COMEC
GSF71_RS01010	COG2131	deaminase
GSF71_RS01015	COG1555	photosystem II stabilization
GSF71_RS01015	COG1596	polysaccharide export
GSF71_RS01025	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
GSF71_RS01030	COG0742	ribosomal rna small subunit methyltransferase
GSF71_RS01035	COG4471	UPF0298 protein
GSF71_RS01050	COG4838	Belongs to the UPF0358 family
GSF71_RS01060	COG0483	inositol monophosphate 1-phosphatase activity
GSF71_RS01095	COG0242	peptide deformylase activity
GSF71_RS01125	COG1597	lipid kinase activity
GSF71_RS01135	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
GSF71_RS01145	COG1051	belongs to the nudix hydrolase family
GSF71_RS01150	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
GSF71_RS01160	COG0302	gtp cyclohydrolase
GSF71_RS01165	COG0302	gtp cyclohydrolase
GSF71_RS01165	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
GSF71_RS01190	COG5290	Psort location Cytoplasmic, score
GSF71_RS01205	COG0719	Fe-S assembly protein
GSF71_RS01215	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
GSF71_RS01220	COG0719	Fe-S assembly protein
GSF71_RS01235	COG2011	ABC-type metal ion transport system permease component
GSF71_RS01240	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
GSF71_RS01245	COG0509	glycine decarboxylation via glycine cleavage system
GSF71_RS01250	COG0772	Belongs to the SEDS family
GSF71_RS01260	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
GSF71_RS01275	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
GSF71_RS01285	COG0355	proton-transporting ATP synthase activity, rotational mechanism
GSF71_RS01290	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
GSF71_RS01295	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
GSF71_RS01300	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
GSF71_RS01305	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
GSF71_RS01310	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
GSF71_RS01315	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
GSF71_RS01320	COG0356	it plays a direct role in the translocation of protons across the membrane
GSF71_RS01325	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
GSF71_RS01330	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
GSF71_RS01335	COG0009	L-threonylcarbamoyladenylate synthase
GSF71_RS01340	COG2890	protein-(glutamine-N5) methyltransferase activity
GSF71_RS01345	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
GSF71_RS01350	COG1435	thymidine kinase activity
GSF71_RS01355	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
GSF71_RS01360	COG3442	glutamine amidotransferase
GSF71_RS01365	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
GSF71_RS01365	COG0574	Belongs to the PEP-utilizing enzyme family
GSF71_RS01370	COG0517	IMP dehydrogenase activity
GSF71_RS01375	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
GSF71_RS01385	COG1418	mRNA catabolic process
GSF71_RS01390	COG1482	cell wall glycoprotein biosynthetic process
GSF71_RS01395	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
GSF71_RS01400	COG1132	(ABC) transporter
GSF71_RS01410	COG1309	transcriptional regulator
GSF71_RS01415	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
GSF71_RS01420	COG1278	Cold shock
GSF71_RS01445	COG1803	Methylglyoxal synthase
GSF71_RS01485	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
GSF71_RS01505	COG3158	transport of potassium into the cell
GSF71_RS01515	COG2723	6-phospho-beta-galactosidase activity
GSF71_RS01520	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
GSF71_RS01535	COG0589	response to stress
GSF71_RS01560	COG0166	Belongs to the GPI family
GSF71_RS01570	COG4120	Belongs to the binding-protein-dependent transport system permease family
GSF71_RS01575	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
GSF71_RS01580	COG0028	Belongs to the TPP enzyme family
GSF71_RS01625	COG3394	polysaccharide catabolic process
GSF71_RS01635	COG0366	Alpha amylase catalytic
GSF71_RS01645	COG2188	Transcriptional regulator
GSF71_RS01655	COG4485	Bacterial membrane protein, YfhO
GSF71_RS01660	COG4975	Glucose uptake
GSF71_RS01675	COG1368	sulfuric ester hydrolase activity
GSF71_RS01695	COG0402	S-adenosylhomocysteine deaminase activity
GSF71_RS01705	COG0745	RESPONSE REGULATOR receiver
GSF71_RS01715	COG0561	phosphatase activity
GSF71_RS01720	COG0531	amino acid
GSF71_RS01725	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
GSF71_RS01735	COG5016	pyruvate
GSF71_RS01735	COG0511	ligase activity, forming carbon-carbon bonds
GSF71_RS01755	COG3052	prosthetic group binding
GSF71_RS01770	COG0511	ligase activity, forming carbon-carbon bonds
GSF71_RS01780	COG2851	Citrate transporter
GSF71_RS01820	COG0635	Involved in the biosynthesis of porphyrin-containing compound
GSF71_RS01825	COG0196	riboflavin kinase activity
GSF71_RS01830	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
GSF71_RS01850	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
GSF71_RS01855	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
GSF71_RS01865	COG2740	Nucleic-acid-binding protein implicated in transcription termination
GSF71_RS01880	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GSF71_RS01915	COG4974	Belongs to the 'phage' integrase family
GSF71_RS01950	COG2176	DNA-directed DNA polymerase activity
GSF71_RS01955	COG0442	prolyl-tRNA aminoacylation
GSF71_RS01960	COG0750	zinc metalloprotease
GSF71_RS01965	COG4589	Belongs to the CDS family
GSF71_RS01970	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
GSF71_RS01980	COG0233	cytoplasmic translational termination
GSF71_RS01985	COG0528	UMP kinase activity
GSF71_RS01990	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
GSF71_RS01995	COG0052	Belongs to the universal ribosomal protein uS2 family
GSF71_RS02000	COG2827	Endonuclease containing a URI domain
GSF71_RS02005	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
GSF71_RS02010	COG0204	Acyl-transferase
GSF71_RS02015	COG1073	alpha beta
GSF71_RS02020	COG1132	(ABC) transporter
GSF71_RS02025	COG1132	(ABC) transporter
GSF71_RS02030	COG3763	UPF0154 protein
GSF71_RS02035	COG4224	UPF0291 protein
GSF71_RS02040	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
GSF71_RS02045	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
GSF71_RS02050	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
GSF71_RS02050	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
GSF71_RS02055	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
GSF71_RS02060	COG3759	membrane
GSF71_RS02065	COG0393	Putative heavy-metal-binding
GSF71_RS02100	COG0481	GTPase activity
GSF71_RS02125	COG3152	Membrane
GSF71_RS02140	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
GSF71_RS02145	COG0827	DNA restriction-modification system
GSF71_RS02175	COG1459	type II secretion system
GSF71_RS02180	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
GSF71_RS02185	COG0217	transcriptional regulatory protein
GSF71_RS02220	COG2855	membrane
GSF71_RS02225	COG0583	DNA-binding transcription factor activity
GSF71_RS02230	COG0534	Mate efflux family protein
GSF71_RS02240	COG0564	pseudouridine synthase activity
GSF71_RS02245	COG0431	NADPH-dependent FMN reductase
GSF71_RS02255	COG2249	NAD(P)H dehydrogenase (quinone) activity
GSF71_RS02260	COG0174	glutamine synthetase
GSF71_RS02265	COG0789	Transcriptional regulator
GSF71_RS02270	COG0519	Catalyzes the synthesis of GMP from XMP
GSF71_RS02280	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
GSF71_RS02285	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
GSF71_RS02300	COG1940	carbohydrate kinase activity
GSF71_RS02315	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
GSF71_RS02320	COG0267	Belongs to the bacterial ribosomal protein bL33 family
GSF71_RS02340	COG0812	UDP-N-acetylmuramate dehydrogenase activity
GSF71_RS02345	COG0708	Exodeoxyribonuclease III
GSF71_RS02350	COG2176	DNA-directed DNA polymerase activity
GSF71_RS02355	COG0697	spore germination
GSF71_RS02365	COG0802	atpase or kinase
GSF71_RS02370	COG0280	phosphate acetyltransferase
GSF71_RS02375	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
GSF71_RS02380	COG0561	phosphatase activity
GSF71_RS02390	COG1811	Na channel or pump
GSF71_RS02405	COG0517	IMP dehydrogenase activity
GSF71_RS02405	COG0516	GMP reductase activity
GSF71_RS02410	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GSF71_RS02415	COG0351	phosphomethylpyrimidine kinase
GSF71_RS02425	COG4475	Protein of unknown function (DUF436)
GSF71_RS02430	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
GSF71_RS02440	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GSF71_RS02460	COG1177	transmembrane transport
GSF71_RS02465	COG1176	ABC-type spermidine putrescine transport system, permease component I
GSF71_RS02470	COG3842	ATPase activity
GSF71_RS02475	COG0604	alcohol dehydrogenase
GSF71_RS02485	COG1136	(ABC) transporter
GSF71_RS02490	COG0577	efflux transmembrane transporter activity
GSF71_RS02505	COG4585	Histidine kinase
GSF71_RS02515	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
GSF71_RS02520	COG0572	uridine kinase
GSF71_RS02525	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
GSF71_RS02530	COG0072	phenylalanine-tRNA ligase activity
GSF71_RS02535	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
GSF71_RS02540	COG1733	regulation of RNA biosynthetic process
GSF71_RS02550	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GSF71_RS02555	COG1254	Belongs to the acylphosphatase family
GSF71_RS02560	COG0706	membrane insertase activity
GSF71_RS02565	COG5002	protein histidine kinase activity
GSF71_RS02570	COG0745	RESPONSE REGULATOR receiver
GSF71_RS02575	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
GSF71_RS02585	COG1323	Belongs to the UPF0348 family
GSF71_RS02590	COG2226	methyltransferase
GSF71_RS02595	COG0799	negative regulation of ribosome biogenesis
GSF71_RS02600	COG1713	HD superfamily hydrolase involved in NAD metabolism
GSF71_RS02605	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
GSF71_RS02615	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
GSF71_RS02630	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
GSF71_RS02635	COG0291	Belongs to the bacterial ribosomal protein bL35 family
GSF71_RS02640	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
GSF71_RS02645	COG1304	FMN binding
GSF71_RS02650	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
GSF71_RS02655	COG1484	DNA-dependent DNA replication
GSF71_RS02660	COG3611	Membrane attachment protein
GSF71_RS02665	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
GSF71_RS02670	COG0237	dephospho-CoA kinase activity
GSF71_RS02675	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
GSF71_RS02680	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GSF71_RS02680	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GSF71_RS02695	COG3583	domain protein
GSF71_RS02695	COG3584	3D domain protein
GSF71_RS02700	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
GSF71_RS02705	COG0557	exoribonuclease II activity
GSF71_RS02715	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
GSF71_RS02725	COG0531	amino acid
GSF71_RS02740	COG1725	Transcriptional regulator
GSF71_RS02745	COG1073	alpha beta
GSF71_RS02750	COG0018	arginyl-trna synthetase
GSF71_RS02755	COG0577	efflux transmembrane transporter activity
GSF71_RS02755	COG1136	(ABC) transporter
GSF71_RS02770	COG0531	amino acid
GSF71_RS02775	COG2267	carboxylic ester hydrolase activity
GSF71_RS02780	COG0561	phosphatase activity
GSF71_RS02795	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
GSF71_RS02805	COG1187	pseudouridine synthase activity
GSF71_RS02810	COG2244	polysaccharide biosynthetic process
GSF71_RS02815	COG2814	Major facilitator Superfamily
GSF71_RS02820	COG1733	regulation of RNA biosynthetic process
GSF71_RS02825	COG1113	amino acid transport
GSF71_RS02830	COG0495	leucyl-tRNA aminoacylation
GSF71_RS02835	COG1705	Flagellar rod assembly protein muramidase FlgJ
GSF71_RS02835	COG1388	LysM domain
GSF71_RS02840	COG0671	phosphoesterase, PA-phosphatase related
GSF71_RS02845	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
GSF71_RS02850	COG3142	Participates in the control of copper homeostasis
GSF71_RS02860	COG0564	pseudouridine synthase activity
GSF71_RS02865	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
GSF71_RS02870	COG2357	RelA SpoT domain protein
GSF71_RS02890	COG4862	establishment of competence for transformation
GSF71_RS02895	COG1393	Belongs to the ArsC family
GSF71_RS02900	COG1234	tRNA 3'-trailer cleavage
GSF71_RS02915	COG1136	(ABC) transporter
GSF71_RS02920	COG0745	RESPONSE REGULATOR receiver
GSF71_RS02925	COG0642	Histidine kinase
GSF71_RS02935	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GSF71_RS02940	COG0602	queuosine metabolic process
GSF71_RS02950	COG2217	Heavy metal translocating P-type atpase
GSF71_RS02975	COG0542	response to heat
GSF71_RS02995	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
GSF71_RS03000	COG1253	flavin adenine dinucleotide binding
GSF71_RS03005	COG0628	permease
GSF71_RS03010	COG2153	protein acetylation
GSF71_RS03020	COG1442	glycosyl transferase family 8
GSF71_RS03025	COG3557	Belongs to the UPF0374 family
GSF71_RS03030	COG1194	a g-specific adenine glycosylase
GSF71_RS03035	COG2137	regulation of response to DNA damage stimulus
GSF71_RS03045	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GSF71_RS03065	COG3425	synthase
GSF71_RS03075	COG0183	Belongs to the thiolase family
GSF71_RS03105	COG1597	lipid kinase activity
GSF71_RS03115	COG1088	dTDP-glucose 4,6-dehydratase activity
GSF71_RS03125	COG0765	amino acid transport
GSF71_RS03135	COG0242	peptide deformylase activity
GSF71_RS03160	COG1210	Utp--glucose-1-phosphate uridylyltransferase
GSF71_RS03200	COG0438	transferase activity, transferring glycosyl groups
GSF71_RS03205	COG1442	glycosyl transferase family 8
GSF71_RS03210	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
GSF71_RS03215	COG0489	protein tyrosine kinase activity
GSF71_RS03225	COG1316	TRANSCRIPTIONal
GSF71_RS03235	COG0024	Methionine aminopeptidase
GSF71_RS03240	COG0716	FMN binding
GSF71_RS03245	COG2246	polysaccharide biosynthetic process
GSF71_RS03250	COG2246	polysaccharide biosynthetic process
GSF71_RS03255	COG0463	Glycosyl transferase, family 2
GSF71_RS03260	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
GSF71_RS03270	COG2309	aminopeptidase activity
GSF71_RS03285	COG2076	Multidrug Resistance protein
GSF71_RS03305	COG0477	Major facilitator Superfamily
GSF71_RS03310	COG1827	regulation of RNA biosynthetic process
GSF71_RS03315	COG2723	6-phospho-beta-galactosidase activity
GSF71_RS03325	COG1447	Phosphotransferase system cellobiose-specific component IIA
GSF71_RS03335	COG0673	inositol 2-dehydrogenase activity
GSF71_RS03375	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GSF71_RS03380	COG1597	lipid kinase activity
GSF71_RS03385	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
GSF71_RS03390	COG0154	amidase activity
GSF71_RS03415	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
GSF71_RS03430	COG1609	Transcriptional regulator
GSF71_RS03435	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
GSF71_RS03440	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
GSF71_RS03445	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
GSF71_RS03450	COG1705	Flagellar rod assembly protein muramidase FlgJ
GSF71_RS03455	COG0673	inositol 2-dehydrogenase activity
GSF71_RS03465	COG1278	Cold shock
GSF71_RS03490	COG3091	SprT-like family
GSF71_RS03495	COG2183	response to ionizing radiation
GSF71_RS03515	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
GSF71_RS03520	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
GSF71_RS03530	COG1215	transferase activity, transferring glycosyl groups
GSF71_RS03540	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
GSF71_RS03550	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
GSF71_RS03565	COG2826	transposase and inactivated derivatives, IS30 family
GSF71_RS03590	COG2826	transposase and inactivated derivatives, IS30 family
GSF71_RS03600	COG2188	Transcriptional regulator
GSF71_RS03615	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
GSF71_RS03635	COG3104	oligopeptide transport
GSF71_RS03640	COG0494	nUDIX hydrolase
GSF71_RS03675	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
GSF71_RS03680	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
GSF71_RS03685	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
GSF71_RS03700	COG0037	tRNA processing
GSF71_RS03705	COG1098	S1 RNA binding domain
GSF71_RS03715	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
GSF71_RS03725	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
GSF71_RS03730	COG0193	aminoacyl-tRNA hydrolase activity
GSF71_RS03735	COG0039	L-malate dehydrogenase activity
GSF71_RS03755	COG4708	membrane
GSF71_RS03760	COG2337	Toxic component of a toxin-antitoxin (TA) module
GSF71_RS03770	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
GSF71_RS03775	COG0736	holo-[acyl-carrier-protein] synthase activity
GSF71_RS03785	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
GSF71_RS03795	COG0501	Belongs to the peptidase M48B family
GSF71_RS03800	COG1704	LemA family
GSF71_RS03810	COG2814	Major facilitator Superfamily
GSF71_RS03820	COG3548	integral membrane protein
GSF71_RS03830	COG0254	rRNA binding
GSF71_RS03835	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
GSF71_RS03840	COG0504	CTP synthase activity
GSF71_RS03845	COG1940	carbohydrate kinase activity
GSF71_RS03850	COG3343	RNA polymerase activity
GSF71_RS03860	COG0095	Lipoate-protein ligase
GSF71_RS03865	COG1078	dGTPase activity
GSF71_RS03870	COG0561	phosphatase activity
GSF71_RS03880	COG0861	Integral membrane protein TerC family
GSF71_RS03885	COG1970	mechanosensitive ion channel activity
GSF71_RS03890	COG1737	Transcriptional regulator
GSF71_RS03895	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
GSF71_RS03900	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
GSF71_RS03905	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
GSF71_RS03910	COG1376	ErfK ybiS ycfS ynhG family protein
GSF71_RS03915	COG1309	transcriptional regulator
GSF71_RS03920	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
GSF71_RS03925	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
GSF71_RS03935	COG4466	Protein conserved in bacteria
GSF71_RS03940	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
GSF71_RS03950	COG0084	hydrolase, TatD family'
GSF71_RS03955	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GSF71_RS03955	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GSF71_RS03960	COG1801	Protein of unknown function DUF72
GSF71_RS03985	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
GSF71_RS03990	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GSF71_RS03995	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
GSF71_RS04000	COG0222	ribosome binding
GSF71_RS04005	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
GSF71_RS04015	COG2252	PERMEase
GSF71_RS04020	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
GSF71_RS04025	COG0081	regulation of translation
GSF71_RS04030	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
GSF71_RS04040	COG0250	Participates in transcription elongation, termination and antitermination
GSF71_RS04050	COG0267	Belongs to the bacterial ribosomal protein bL33 family
GSF71_RS04060	COG3688	RNA-binding protein containing a PIN domain
GSF71_RS04065	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GSF71_RS04070	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
GSF71_RS04075	COG0215	cysteine-tRNA ligase activity
GSF71_RS04080	COG4956	integral membrane protein (PIN domain superfamily)
GSF71_RS04085	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
GSF71_RS04090	COG0756	dUTP diphosphatase activity
GSF71_RS04110	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GSF71_RS04115	COG1363	Peptidase, m42
GSF71_RS04120	COG1363	Peptidase, m42
GSF71_RS04130	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GSF71_RS04135	COG2188	Transcriptional regulator
GSF71_RS04140	COG1446	asparaginase
GSF71_RS04165	COG1285	pathogenesis
GSF71_RS04170	COG1914	H( )-stimulated, divalent metal cation uptake system
GSF71_RS04180	COG3479	Phenolic acid decarboxylase
GSF71_RS04185	COG1064	alcohol dehydrogenase
GSF71_RS04195	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
GSF71_RS04250	COG1396	sequence-specific DNA binding
GSF71_RS04270	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GSF71_RS04275	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
GSF71_RS04280	COG0101	tRNA pseudouridine synthase activity
GSF71_RS04340	COG1122	ATPase activity
GSF71_RS04345	COG1122	ATPase activity
GSF71_RS04350	COG0203	ribosomal protein L17
GSF71_RS04355	COG0202	RNA polymerase activity
GSF71_RS04360	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
GSF71_RS04365	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
GSF71_RS04370	COG0257	Belongs to the bacterial ribosomal protein bL36 family
GSF71_RS04375	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
GSF71_RS04380	COG0563	adenylate kinase activity
GSF71_RS04390	COG0200	Binds to the 23S rRNA
GSF71_RS04395	COG1841	ribosomal large subunit assembly
GSF71_RS04400	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
GSF71_RS04405	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
GSF71_RS04410	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
GSF71_RS04415	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
GSF71_RS04425	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
GSF71_RS04430	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
GSF71_RS04435	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
GSF71_RS04440	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
GSF71_RS04445	COG0255	Belongs to the universal ribosomal protein uL29 family
GSF71_RS04450	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
GSF71_RS04455	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
GSF71_RS04460	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
GSF71_RS04465	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
GSF71_RS04470	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
GSF71_RS04475	COG0089	rRNA binding
GSF71_RS04480	COG0088	Forms part of the polypeptide exit tunnel
GSF71_RS04485	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
GSF71_RS04490	COG0051	transcription antitermination factor activity, RNA binding
GSF71_RS04495	COG1335	isochorismatase
GSF71_RS04500	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
GSF71_RS04505	COG0049	tRNA binding
GSF71_RS04510	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
GSF71_RS04515	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
GSF71_RS04525	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
GSF71_RS04530	COG0085	RNA polymerase activity
GSF71_RS04535	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
GSF71_RS04545	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
GSF71_RS04550	COG0542	response to heat
GSF71_RS04555	COG4463	regulation of RNA biosynthetic process
GSF71_RS04635	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GSF71_RS04655	COG5617	Psort location CytoplasmicMembrane, score
GSF71_RS04665	COG1940	carbohydrate kinase activity
GSF71_RS04670	COG0366	Alpha amylase catalytic
GSF71_RS04680	COG1621	beta-fructofuranosidase activity
GSF71_RS04695	COG0662	Cupin 2, conserved barrel domain protein
GSF71_RS04695	COG2207	Transcriptional regulator
GSF71_RS04700	COG0789	Transcriptional regulator
GSF71_RS04710	COG2188	Transcriptional regulator
GSF71_RS04715	COG1511	domain protein
GSF71_RS04720	COG1511	domain protein
GSF71_RS04735	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
GSF71_RS04745	COG1428	Deoxynucleoside kinase
GSF71_RS04820	COG0833	amino acid
GSF71_RS04850	COG1959	2 iron, 2 sulfur cluster binding
GSF71_RS04880	COG0028	Belongs to the TPP enzyme family
GSF71_RS04885	COG2837	iron assimilation
GSF71_RS04935	COG0577	efflux transmembrane transporter activity
GSF71_RS04940	COG1136	(ABC) transporter
GSF71_RS04945	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
GSF71_RS04950	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
GSF71_RS04955	COG0514	ATP-dependent DNA helicase (RecQ)
GSF71_RS04970	COG1881	PFAM PEBP family protein
GSF71_RS04980	COG1335	isochorismatase
GSF71_RS04985	COG1522	sequence-specific DNA binding
GSF71_RS05000	COG2160	L-arabinose isomerase activity
GSF71_RS05020	COG1609	Transcriptional regulator
GSF71_RS05040	COG0110	maltose O-acetyltransferase activity
GSF71_RS05050	COG1174	glycine betaine transport
GSF71_RS05060	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GSF71_RS05065	COG2814	Major facilitator Superfamily
GSF71_RS05080	COG1063	alcohol dehydrogenase
GSF71_RS05090	COG0561	phosphatase activity
GSF71_RS05125	COG0488	(ABC) transporter
GSF71_RS05130	COG0445	tRNA wobble uridine modification
GSF71_RS05135	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
GSF71_RS05140	COG1847	R3H domain protein
GSF71_RS05155	COG0706	membrane insertase activity
GSF71_RS05160	COG0594	ribonuclease P activity
GSF71_RS05165	COG0230	Belongs to the bacterial ribosomal protein bL34 family
GSF71_RS05170	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
GSF71_RS05175	COG0592	DNA-directed DNA polymerase activity
GSF71_RS05180	COG2501	S4 domain
GSF71_RS05185	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
GSF71_RS05190	COG0187	DNA topoisomerase II activity
GSF71_RS05195	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
GSF71_RS05200	COG0360	Binds together with S18 to 16S ribosomal RNA
GSF71_RS05205	COG0629	single-stranded DNA binding
GSF71_RS05210	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
GSF71_RS05220	COG0359	binds to the 23S rRNA
GSF71_RS05225	COG0305	Participates in initiation and elongation during chromosome replication
GSF71_RS05235	COG0357	Ribosomal RNA small subunit methyltransferase G
GSF71_RS05240	COG1475	DNA binding
GSF71_RS05245	COG1192	Involved in chromosome partitioning
GSF71_RS05250	COG1475	DNA binding
GSF71_RS05255	COG4481	Protein conserved in bacteria
GSF71_RS05260	COG0012	GTP binding
GSF71_RS05270	COG1073	alpha beta
GSF71_RS05280	COG1780	Probably involved in ribonucleotide reductase function
GSF71_RS05305	COG1307	EDD domain protein, DegV family
GSF71_RS05310	COG1253	flavin adenine dinucleotide binding
GSF71_RS05315	COG0656	L-ascorbic acid biosynthetic process
GSF71_RS05330	COG2814	Major facilitator Superfamily
GSF71_RS05335	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
GSF71_RS05340	COG2365	Tyrosine phosphatase family
GSF71_RS05355	COG2818	Glycosylase
GSF71_RS05365	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
GSF71_RS05385	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
GSF71_RS05390	COG0628	permease
GSF71_RS05405	COG1181	Belongs to the D-alanine--D-alanine ligase family
GSF71_RS05410	COG0071	Belongs to the small heat shock protein (HSP20) family
GSF71_RS05415	COG4152	abc transporter atp-binding protein
GSF71_RS05425	COG3590	peptidase
GSF71_RS05430	COG0110	maltose O-acetyltransferase activity
GSF71_RS05440	COG0352	thiamine-phosphate diphosphorylase activity
GSF71_RS05445	COG0351	phosphomethylpyrimidine kinase
GSF71_RS05450	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
GSF71_RS05455	COG2190	(PTS) system
GSF71_RS05455	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GSF71_RS05455	COG1263	PTS System
GSF71_RS05470	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
GSF71_RS05475	COG2252	PERMEase
GSF71_RS05485	COG3764	Sortase (surface protein transpeptidase)
GSF71_RS05490	COG3620	sequence-specific DNA binding
GSF71_RS05495	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
GSF71_RS05505	COG0745	RESPONSE REGULATOR receiver
GSF71_RS05525	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
GSF71_RS05530	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GSF71_RS05535	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
GSF71_RS05545	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
GSF71_RS05550	COG2252	PERMEase
GSF71_RS05555	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
GSF71_RS05560	COG0697	spore germination
GSF71_RS05575	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GSF71_RS05580	COG2814	Major facilitator Superfamily
GSF71_RS05585	COG1288	antiporter activity
GSF71_RS05605	COG1794	racemase activity, acting on amino acids and derivatives
GSF71_RS05610	COG0588	phosphoglycerate mutase activity
GSF71_RS05630	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
GSF71_RS05645	COG0194	GDP metabolic process
GSF71_RS05655	COG0735	belongs to the Fur family
GSF71_RS05720	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
GSF71_RS05730	COG2814	Major facilitator Superfamily
GSF71_RS05735	COG1070	Carbohydrate kinase
GSF71_RS05740	COG3254	rhamnose metabolic process
GSF71_RS05745	COG4806	L-rhamnose isomerase
GSF71_RS05750	COG0235	Class ii aldolase
GSF71_RS05765	COG1940	carbohydrate kinase activity
GSF71_RS05770	COG0531	amino acid
GSF71_RS05775	COG0531	amino acid
GSF71_RS05780	COG1136	(ABC) transporter
GSF71_RS05785	COG0577	efflux transmembrane transporter activity
GSF71_RS05790	COG1904	glucuronate isomerase
GSF71_RS05795	COG1609	Transcriptional regulator
GSF71_RS05800	COG0588	phosphoglycerate mutase activity
GSF71_RS05815	COG0475	glutathione-regulated potassium exporter activity
GSF71_RS05815	COG0569	domain protein
GSF71_RS05820	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
GSF71_RS05825	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
GSF71_RS05835	COG1072	(Pantothenic acid kinase))
GSF71_RS05840	COG0519	Catalyzes the synthesis of GMP from XMP
GSF71_RS05860	COG0494	nUDIX hydrolase
GSF71_RS05890	COG3681	Belongs to the UPF0597 family
GSF71_RS05895	COG0814	amino acid
GSF71_RS05910	COG0640	Transcriptional regulator
GSF71_RS05915	COG1442	glycosyl transferase family 8
GSF71_RS05935	COG1028	Short-chain dehydrogenase reductase Sdr
GSF71_RS05940	COG2261	transglycosylase associated protein
GSF71_RS05955	COG1302	Protein conserved in bacteria
GSF71_RS06005	COG4690	dipeptidase activity
GSF71_RS06010	COG1121	(ABC) transporter
GSF71_RS06015	COG1108	ABC-type Mn2 Zn2 transport systems permease components
GSF71_RS06030	COG0477	Major facilitator Superfamily
GSF71_RS06045	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GSF71_RS06055	COG1940	carbohydrate kinase activity
GSF71_RS06065	COG2190	(PTS) system
GSF71_RS06065	COG2211	Major facilitator Superfamily
GSF71_RS06075	COG0488	(ABC) transporter
GSF71_RS06080	COG0531	amino acid
GSF71_RS06125	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
GSF71_RS06135	COG4975	Glucose uptake
GSF71_RS06140	COG1869	D-ribose catabolic process
GSF71_RS06215	COG0583	DNA-binding transcription factor activity
GSF71_RS06255	COG2409	Drug exporters of the RND superfamily
GSF71_RS06255	COG1033	growth of symbiont in host cell
GSF71_RS06275	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
GSF71_RS06280	COG2826	transposase and inactivated derivatives, IS30 family
GSF71_RS06310	COG0446	pyridine nucleotide-disulphide oxidoreductase
GSF71_RS06375	COG3118	belongs to the thioredoxin family
GSF71_RS06380	COG1396	sequence-specific DNA binding
GSF71_RS06385	COG2807	transmembrane transport
GSF71_RS06410	COG1940	carbohydrate kinase activity
GSF71_RS06420	COG1131	(ABC) transporter
GSF71_RS06435	COG0583	DNA-binding transcription factor activity
GSF71_RS06440	COG0110	maltose O-acetyltransferase activity
GSF71_RS06445	COG4221	oxidoreductase activity
GSF71_RS06450	COG0308	aminopeptidase N
GSF71_RS06465	COG0789	Transcriptional regulator
GSF71_RS06470	COG1846	Transcriptional regulator
GSF71_RS06475	COG1132	(ABC) transporter
GSF71_RS06500	COG0656	L-ascorbic acid biosynthetic process
GSF71_RS06505	COG0789	Transcriptional regulator
GSF71_RS06540	COG1914	H( )-stimulated, divalent metal cation uptake system
GSF71_RS06565	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
GSF71_RS06570	COG1957	nucleoside hydrolase
GSF71_RS06575	COG1522	sequence-specific DNA binding
GSF71_RS06575	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GSF71_RS06580	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GSF71_RS06585	COG0135	phosphoribosylanthranilate isomerase activity
GSF71_RS06605	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
GSF71_RS06610	COG0667	Aldo Keto reductase
GSF71_RS06625	COG1695	Transcriptional regulator
GSF71_RS06630	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
GSF71_RS06635	COG2814	Major facilitator Superfamily
GSF71_RS06645	COG1132	(ABC) transporter
GSF71_RS06650	COG1132	(ABC) transporter
GSF71_RS06655	COG3973	AAA domain
GSF71_RS06660	COG2365	Tyrosine phosphatase family
GSF71_RS06665	COG0516	GMP reductase activity
GSF71_RS06665	COG0517	IMP dehydrogenase activity
GSF71_RS06675	COG5002	protein histidine kinase activity
GSF71_RS06680	COG1686	Belongs to the peptidase S11 family
GSF71_RS06685	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
GSF71_RS06700	COG1121	(ABC) transporter
GSF71_RS06705	COG1108	ABC-type Mn2 Zn2 transport systems permease components
GSF71_RS06715	COG1316	TRANSCRIPTIONal
GSF71_RS06720	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
GSF71_RS06730	COG2188	Transcriptional regulator
GSF71_RS06735	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
GSF71_RS06740	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
GSF71_RS06770	COG1737	Transcriptional regulator
GSF71_RS06775	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
GSF71_RS06785	COG2610	gluconate transmembrane transporter activity
GSF71_RS06805	COG0488	(ABC) transporter
GSF71_RS06835	COG2814	Major facilitator Superfamily
GSF71_RS06870	COG0702	epimerase
GSF71_RS06875	COG1760	l-serine dehydratase
GSF71_RS06885	COG1297	OPT oligopeptide transporter protein
GSF71_RS06900	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GSF71_RS06910	COG0561	phosphatase activity
GSF71_RS06920	COG3973	AAA domain
GSF71_RS06945	COG0392	lysyltransferase activity
GSF71_RS06945	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
GSF71_RS06950	COG2813	Specifically methylates the guanine in position
GSF71_RS06960	COG0590	tRNA wobble adenosine to inosine editing
GSF71_RS06970	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
GSF71_RS06975	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
GSF71_RS06980	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
GSF71_RS06990	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
GSF71_RS06995	COG3870	Protein conserved in bacteria
GSF71_RS07000	COG0470	DNA polymerase III
GSF71_RS07005	COG4467	Involved in initiation control of chromosome replication
GSF71_RS07030	COG1214	PFAM Peptidase M22, glycoprotease
GSF71_RS07040	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
GSF71_RS07050	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GSF71_RS07060	COG0488	(ABC) transporter
GSF71_RS07070	COG1266	CAAX protease self-immunity
GSF71_RS07075	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
GSF71_RS07080	COG0459	protein refolding
GSF71_RS07085	COG0531	amino acid
GSF71_RS07090	COG1692	metallophosphoesterase
GSF71_RS07095	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
GSF71_RS07105	COG0424	maF-like protein
GSF71_RS07115	COG0632	four-way junction helicase activity
GSF71_RS07120	COG2255	four-way junction helicase activity
GSF71_RS07125	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
GSF71_RS07135	COG2235	arginine
GSF71_RS07150	COG0436	Aminotransferase
GSF71_RS07165	COG1288	antiporter activity
GSF71_RS07170	COG0343	queuine tRNA-ribosyltransferase activity
GSF71_RS07175	COG1862	Preprotein translocase
GSF71_RS07180	COG1012	belongs to the aldehyde dehydrogenase family
GSF71_RS07180	COG1454	alcohol dehydrogenase
GSF71_RS07185	COG1321	iron dependent repressor
GSF71_RS07190	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
GSF71_RS07195	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
GSF71_RS07200	COG4109	DRTGG domain
GSF71_RS07205	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
GSF71_RS07210	COG0513	Belongs to the DEAD box helicase family
GSF71_RS07220	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
GSF71_RS07225	COG4472	Bacterial protein of unknown function (DUF965)
GSF71_RS07230	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
GSF71_RS07235	COG3906	Belongs to the UPF0473 family
GSF71_RS07240	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
GSF71_RS07250	COG1193	negative regulation of DNA recombination
GSF71_RS07255	COG3118	belongs to the thioredoxin family
GSF71_RS07270	COG1696	Membrane protein involved in D-alanine export
GSF71_RS07275	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GSF71_RS07280	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
GSF71_RS07285	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GSF71_RS07290	COG1120	ATPase activity
GSF71_RS07295	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GSF71_RS07300	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GSF71_RS07305	COG0492	ferredoxin-NADP+ reductase activity
GSF71_RS07315	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
GSF71_RS07320	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
GSF71_RS07340	COG0668	transmembrane transport
GSF71_RS07355	COG0006	proline dipeptidase activity
GSF71_RS07360	COG1609	Transcriptional regulator
GSF71_RS07365	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GSF71_RS07370	COG0363	glucosamine-6-phosphate deaminase activity
GSF71_RS07380	COG2814	Major facilitator Superfamily
GSF71_RS07400	COG2217	Heavy metal translocating P-type atpase
GSF71_RS07405	COG0640	Transcriptional regulator
GSF71_RS07420	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
GSF71_RS07430	COG4470	Protein conserved in bacteria
GSF71_RS07435	COG0647	UMP catabolic process
GSF71_RS07445	COG0586	Pfam SNARE associated Golgi protein
GSF71_RS07450	COG0492	ferredoxin-NADP+ reductase activity
GSF71_RS07460	COG1098	S1 RNA binding domain
GSF71_RS07635	COG0583	DNA-binding transcription factor activity
GSF71_RS07650	COG0251	oxidation-reduction process
GSF71_RS07665	COG0167	dihydroorotate dehydrogenase activity
GSF71_RS07670	COG1011	Hydrolase
GSF71_RS07685	COG3715	PTS system
GSF71_RS07690	COG3716	PTS system mannose fructose sorbose family IID component
GSF71_RS07705	COG1028	Short-chain dehydrogenase reductase Sdr
GSF71_RS07735	COG0438	transferase activity, transferring glycosyl groups
GSF71_RS07745	COG2084	Dehydrogenase
GSF71_RS07755	COG1368	sulfuric ester hydrolase activity
GSF71_RS07760	COG0735	belongs to the Fur family
GSF71_RS07810	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
GSF71_RS07815	COG0477	Major facilitator Superfamily
GSF71_RS07820	COG2706	6-phosphogluconolactonase activity
GSF71_RS07830	COG0628	permease
GSF71_RS07840	COG0516	GMP reductase activity
GSF71_RS07865	COG1674	ftsk spoiiie
GSF71_RS07870	COG0612	Peptidase, M16
GSF71_RS07875	COG0612	Peptidase, M16
GSF71_RS07880	COG1028	Short-chain dehydrogenase reductase Sdr
GSF71_RS07885	COG1426	Protein conserved in bacteria
GSF71_RS07890	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
GSF71_RS07895	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
GSF71_RS07900	COG1418	mRNA catabolic process
GSF71_RS07905	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
GSF71_RS07910	COG1739	Uncharacterized protein family UPF0029
GSF71_RS07915	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
GSF71_RS07930	COG0653	protein targeting
GSF71_RS07940	COG2884	Cell division ATP-binding protein ftsE
GSF71_RS07945	COG2177	Part of the ABC transporter FtsEX involved in
GSF71_RS07955	COG0745	RESPONSE REGULATOR receiver
GSF71_RS07960	COG5002	protein histidine kinase activity
GSF71_RS07970	COG0573	inorganic phosphate transmembrane transporter activity
GSF71_RS07975	COG0581	inorganic phosphate transmembrane transporter activity
GSF71_RS07980	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
GSF71_RS07985	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
GSF71_RS07990	COG0704	Plays a role in the regulation of phosphate uptake
GSF71_RS08005	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GSF71_RS08015	COG1983	PspC domain protein
GSF71_RS08025	COG1950	PFAM Membrane protein of
GSF71_RS08030	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
GSF71_RS08035	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
GSF71_RS08040	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
GSF71_RS08050	COG0492	ferredoxin-NADP+ reductase activity
GSF71_RS08055	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GSF71_RS08065	COG0556	nucleotide-excision repair
GSF71_RS08080	COG1660	Displays ATPase and GTPase activities
GSF71_RS08085	COG0391	Required for morphogenesis under gluconeogenic growth conditions
GSF71_RS08090	COG1481	regulation of sporulation
GSF71_RS08095	COG1846	Transcriptional regulator
GSF71_RS08105	COG0740	serine-type endopeptidase activity
GSF71_RS08110	COG1705	Flagellar rod assembly protein muramidase FlgJ
GSF71_RS08115	COG1705	Flagellar rod assembly protein muramidase FlgJ
GSF71_RS08120	COG1957	nucleoside hydrolase
GSF71_RS08135	COG0702	epimerase
GSF71_RS08140	COG1733	regulation of RNA biosynthetic process
GSF71_RS08145	COG4221	oxidoreductase activity
GSF71_RS08150	COG0789	Transcriptional regulator
GSF71_RS08165	COG0604	alcohol dehydrogenase
GSF71_RS08185	COG2094	Belongs to the DNA glycosylase MPG family
GSF71_RS08190	COG1131	(ABC) transporter
GSF71_RS08205	COG4585	Histidine kinase
GSF71_RS08210	COG2197	response regulator
GSF71_RS08225	COG1764	response to oxidative stress
GSF71_RS08235	COG2826	transposase and inactivated derivatives, IS30 family
GSF71_RS08255	COG3279	Response regulator of the LytR AlgR family
GSF71_RS08280	COG3279	Response regulator of the LytR AlgR family
GSF71_RS08335	COG0446	pyridine nucleotide-disulphide oxidoreductase
GSF71_RS08345	COG1811	Na channel or pump
GSF71_RS08350	COG0583	DNA-binding transcription factor activity
GSF71_RS08355	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
GSF71_RS08360	COG0163	prenyltransferase activity
GSF71_RS08370	COG0584	glycerophosphoryl diester phosphodiesterase
GSF71_RS08375	COG4690	dipeptidase activity
GSF71_RS08390	COG2390	Transcriptional regulator
GSF71_RS08400	COG0126	phosphoglycerate kinase activity
GSF71_RS08405	COG0149	triose-phosphate isomerase activity
GSF71_RS08410	COG0148	phosphopyruvate hydratase activity
GSF71_RS08445	COG1438	arginine binding
GSF71_RS08470	COG0564	pseudouridine synthase activity
GSF71_RS08475	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GSF71_RS08480	COG3679	Belongs to the UPF0342 family
GSF71_RS08485	COG0420	3'-5' exonuclease activity
GSF71_RS08490	COG4717	serine-type aminopeptidase activity
GSF71_RS08495	COG3481	metal-dependent phosphohydrolase, HD sub domain
GSF71_RS08500	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GSF71_RS08510	COG0537	adenosine 5'-monophosphoramidase activity
GSF71_RS08515	COG1131	(ABC) transporter
GSF71_RS08520	COG4473	ABC transporter
GSF71_RS08525	COG0510	thiamine kinase activity
GSF71_RS08530	COG0220	tRNA (guanine-N7-)-methyltransferase activity
GSF71_RS08540	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GSF71_RS08545	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GSF71_RS08550	COG0367	asparagine synthase
GSF71_RS08555	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
GSF71_RS08585	COG2936	dipeptidyl-peptidase activity
GSF71_RS08590	COG1607	acyl-coa hydrolase
GSF71_RS08600	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
GSF71_RS08600	COG2755	lipolytic protein G-D-S-L family
GSF71_RS08605	COG3942	CHAP domain
GSF71_RS08615	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
GSF71_RS08620	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
GSF71_RS08625	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
GSF71_RS08630	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
GSF71_RS08635	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
GSF71_RS08640	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
GSF71_RS08645	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
GSF71_RS08650	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
GSF71_RS08655	COG0047	phosphoribosylformylglycinamidine synthase activity
GSF71_RS08660	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
GSF71_RS08665	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
GSF71_RS08670	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
GSF71_RS08675	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
GSF71_RS08680	COG0138	bifunctional purine biosynthesis protein purh
GSF71_RS08685	COG0151	Belongs to the GarS family
GSF71_RS08690	COG1304	FMN binding
GSF71_RS08710	COG0261	This protein binds to 23S rRNA in the presence of protein L20
GSF71_RS08720	COG0211	Belongs to the bacterial ribosomal protein bL27 family
GSF71_RS08725	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
GSF71_RS08730	COG1302	Protein conserved in bacteria
GSF71_RS08735	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
GSF71_RS08740	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
GSF71_RS08745	COG1570	exodeoxyribonuclease VII activity
GSF71_RS08750	COG1722	exodeoxyribonuclease VII activity
GSF71_RS08755	COG0142	geranyltranstransferase activity
GSF71_RS08760	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
GSF71_RS08765	COG1438	arginine binding
GSF71_RS08785	COG0194	GDP metabolic process
GSF71_RS08790	COG1758	RNA polymerase activity
GSF71_RS08795	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
GSF71_RS08800	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
GSF71_RS08805	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
GSF71_RS08810	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
GSF71_RS08810	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
GSF71_RS08820	COG0515	serine threonine protein kinase
GSF71_RS08820	COG2815	serine threonine protein kinase
GSF71_RS08825	COG1162	GTPase activity
GSF71_RS08830	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
GSF71_RS08835	COG1564	THIamine pyrophosphokinase
GSF71_RS08840	COG0227	Belongs to the bacterial ribosomal protein bL28 family
GSF71_RS08845	COG1302	Protein conserved in bacteria
GSF71_RS08850	COG1461	Dihydroxyacetone kinase
GSF71_RS08855	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
GSF71_RS08860	COG0416	fatty acid biosynthetic process
GSF71_RS08865	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GSF71_RS08870	COG4166	transmembrane transport
GSF71_RS08875	COG0601	transmembrane transport
GSF71_RS08880	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GSF71_RS08885	COG0444	Belongs to the ABC transporter superfamily
GSF71_RS08890	COG4608	Belongs to the ABC transporter superfamily
GSF71_RS08895	COG0571	ribonuclease III activity
GSF71_RS08900	COG1196	nuclear chromosome segregation
GSF71_RS08905	COG0552	protein localization to endoplasmic reticulum
GSF71_RS08925	COG3493	citrate carrier protein
GSF71_RS08935	COG3052	prosthetic group binding
GSF71_RS08955	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
GSF71_RS08960	COG1929	Belongs to the glycerate kinase type-1 family
GSF71_RS08965	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
GSF71_RS08970	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
GSF71_RS08975	COG0228	four-way junction DNA binding
GSF71_RS08980	COG1837	Belongs to the UPF0109 family
GSF71_RS08985	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
GSF71_RS08990	COG0336	Belongs to the RNA methyltransferase TrmD family
GSF71_RS08995	COG0335	large ribosomal subunit rRNA binding
GSF71_RS09060	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
GSF71_RS09080	COG2264	protein methyltransferase activity
GSF71_RS09085	COG1385	rRNA (uridine-N3-)-methyltransferase activity
GSF71_RS09095	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
GSF71_RS09100	COG1490	D-aminoacyl-tRNA deacylase activity
GSF71_RS09120	COG2001	Belongs to the MraZ family
GSF71_RS09125	COG0275	rRNA processing
GSF71_RS09140	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
GSF71_RS09145	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
GSF71_RS09150	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
GSF71_RS09165	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
GSF71_RS09170	COG1799	cell septum assembly
GSF71_RS09180	COG2302	S4 RNA-binding domain
GSF71_RS09185	COG3599	regulation of cell shape
GSF71_RS09190	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
GSF71_RS09220	COG1312	Catalyzes the dehydration of D-mannonate
GSF71_RS09225	COG1904	glucuronate isomerase
GSF71_RS09235	COG3775	system Galactitol-specific IIC component
GSF71_RS09240	COG0800	Aldolase
GSF71_RS09245	COG1414	Transcriptional regulator
GSF71_RS09250	COG0246	Mannitol dehydrogenase
GSF71_RS09255	COG2721	sulfolactate sulfo-lyase activity
GSF71_RS09260	COG2211	Major facilitator Superfamily
GSF71_RS09270	COG1874	Beta-galactosidase
GSF71_RS09275	COG2211	Major facilitator Superfamily
GSF71_RS09285	COG2211	Major facilitator Superfamily
GSF71_RS09295	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
GSF71_RS09330	COG1070	Carbohydrate kinase
GSF71_RS09335	COG3254	rhamnose metabolic process
GSF71_RS09340	COG4806	L-rhamnose isomerase
GSF71_RS09345	COG0235	Class ii aldolase
GSF71_RS09355	COG1028	Short-chain dehydrogenase reductase Sdr
GSF71_RS09360	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GSF71_RS09395	COG2211	Major facilitator Superfamily
GSF71_RS09400	COG3507	Belongs to the glycosyl hydrolase 43 family
GSF71_RS09405	COG2115	Belongs to the xylose isomerase family
GSF71_RS09430	COG0445	tRNA wobble uridine modification
GSF71_RS09435	COG2271	Major facilitator Superfamily
GSF71_RS09440	COG1609	Transcriptional regulator
GSF71_RS09450	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
GSF71_RS09455	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
GSF71_RS09460	COG2017	converts alpha-aldose to the beta-anomer
GSF71_RS09465	COG1278	Cold shock
GSF71_RS09470	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
GSF71_RS09475	COG2814	Major facilitator Superfamily
GSF71_RS09480	COG3853	Toxic anion resistance protein (TelA)
GSF71_RS09490	COG0494	nUDIX hydrolase
GSF71_RS09500	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
GSF71_RS09515	COG1619	proteins homologs of microcin C7 resistance protein MccF
GSF71_RS09520	COG1122	ATPase activity
GSF71_RS09530	COG0310	cobalt ion transport
GSF71_RS09535	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GSF71_RS09540	COG3875	lactate racemase activity
GSF71_RS09545	COG1691	(AIR) carboxylase
GSF71_RS09550	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
GSF71_RS09555	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
GSF71_RS09560	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
GSF71_RS09570	COG1606	tRNA processing
GSF71_RS09575	COG1104	cysteine desulfurase activity
GSF71_RS09585	COG0482	sulfurtransferase activity
GSF71_RS09590	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
GSF71_RS09595	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
GSF71_RS09600	COG0813	purine-nucleoside phosphorylase activity
GSF71_RS09605	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
GSF71_RS09615	COG2390	Transcriptional regulator
GSF71_RS09620	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
GSF71_RS09625	COG0446	pyridine nucleotide-disulphide oxidoreductase
GSF71_RS09640	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
GSF71_RS09660	COG4335	DNA alkylation repair
GSF71_RS09680	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
GSF71_RS09685	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GSF71_RS09690	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GSF71_RS09700	COG1028	Short-chain dehydrogenase reductase Sdr
GSF71_RS09705	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GSF71_RS09710	COG0511	ligase activity, forming carbon-carbon bonds
GSF71_RS09715	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
GSF71_RS09720	COG0439	Biotin carboxylase
GSF71_RS09725	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
GSF71_RS09735	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
GSF71_RS09745	COG1268	BioY protein
GSF71_RS09785	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GSF71_RS09805	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
GSF71_RS09820	COG4493	Belongs to the UPF0637 family
GSF71_RS09825	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
GSF71_RS09830	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
GSF71_RS09835	COG1104	cysteine desulfurase activity
GSF71_RS09840	COG0301	tRNA thio-modification
GSF71_RS09845	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
GSF71_RS09850	COG0525	valine-tRNA ligase activity
GSF71_RS09860	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GSF71_RS09865	COG2003	Belongs to the UPF0758 family
GSF71_RS09870	COG1077	Cell shape determining protein MreB Mrl
GSF71_RS09875	COG1792	Involved in formation and maintenance of cell shape
GSF71_RS09885	COG0850	regulation of cytokinetic process
GSF71_RS09890	COG2894	cell division
GSF71_RS09895	COG0765	amino acid transport
GSF71_RS09900	COG1126	abc transporter atp-binding protein
GSF71_RS09905	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GSF71_RS09910	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GSF71_RS09915	COG3103	Sh3 type 3 domain protein
GSF71_RS09915	COG4991	sh3 domain protein
GSF71_RS09915	COG0860	N-Acetylmuramoyl-L-alanine amidase
GSF71_RS09920	COG0124	histidyl-tRNA synthetase
GSF71_RS09925	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
GSF71_RS09935	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GSF71_RS09940	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GSF71_RS09945	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin